LOCUS       DAPSKH010000001       143450 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPSKH010000001 DAPSKH010000000
VERSION     DAPSKH010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 143450)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 143450)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..143450
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.001"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(91..1527)
                     /locus_tag="RPH49_000001"
     CDS             complement(91..1527)
                     /locus_tag="RPH49_000001"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDY5123203.1"
                     /translation="MTKLPQNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKA
                     RQITESIDPNHYYPNHEGIDFYHRYKEDIALFKEMGLKCLRTSIAWTRIFPNGDEDVP
                     NEEGLAFYDRIFDELIAQGIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVV
                     FERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLAS
                     ALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYP
                     SYAKKMLARKGYDFGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGG
                     LNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIH
                     DDYRIEYLKVHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDN
                     DGHGTMERLKKDSFYWYKQVIASNGDKL"
     gene            complement(1543..2334)
                     /locus_tag="RPH49_000002"
     CDS             complement(1543..2334)
                     /locus_tag="RPH49_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDY5123204.1"
                     /translation="MSNKYKDQAQDILTAVGGVENIVDVTYDTKGITIHMQHTIPSTA
                     NEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKDANVEEGANTDNINSQDTS
                     YTPQAKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGL
                     ISMIVPTKHAIGIRSEEGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQ
                     QYIQEQGYNSDVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN"
     gene            2483..3187
                     /locus_tag="RPH49_000003"
     CDS             2483..3187
                     /locus_tag="RPH49_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5123205.1"
                     /translation="MLKYEHIAKQLNAFIHHSNFKPGDKLPSVTQLKERYQVSKSTII
                     KALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEI
                     ATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIF
                     DYLESNMKLRIGFSDIFFNVDQLNSSEAALLQLSKGEPCLRYHQTFYTMTGKPFDSSD
                     IVFHYRHAQFYIPSKK"
     gene            complement(3413..5704)
                     /locus_tag="RPH49_000004"
     CDS             complement(3413..5704)
                     /locus_tag="RPH49_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cbb3-type cytochrome c oxidase subunit I"
                     /protein_id="HDY5123206.1"
                     /translation="MSMQSSYKRLVKVLLTILVIVFSILLVGGWYIFKNEAPRPTKIV
                     DQQGHTLVTKGELISGQAIYEKYGLTDYGSYLGNGSYLGPDYTAEALHHYLIGMRKYY
                     AQDIYHKQLHKLNHAELAVVKDKVMKEIRINRYSEKEDQLVLTPGQVYGLKYLQDYYK
                     KEFVNNPKQVGLNENMIKQFQNDDYMVAGNKVEHLSQFFFWGAWLSSTDRPGKTFSYT
                     NNWPYDVDAGNTLPSAGILWTAISVTLLIAGLAFIIYIQKRYQFDMKPTYESERELPK
                     IEVDRKITDSQRKVGKYLVVVMLLFLVQILLGELLAHYYVENKFFGIEIQRLFPFNIA
                     KTWHVQLVIFWVATTWLAAGIYIVPKVLGKEPKKQGVLVDILFWALIIVVMGSMIGEW
                     GHILGWIDSHWWLFGHFGWEYIELGKFWQILFIVGMVLWVIILCRGFLPAIRNKVQVN
                     HDKRHLLTLLFVGAIAIPLFYLASLFIMPNSHVTFADYWRWWIVHLWVEGIFEAFAVV
                     LIGFLMVNMKLTTIETTIRALYFQLILLLGTGIVGMGHHYYWQGDHSIWLALGSCFSA
                     LEVVPLCLLIWEAYTHYRLYKNSDIAFPYKGTFIFLASTGLWNAIGAGALGFLINTPA
                     VNYFEHGTQWTAAHAHGSMAGVYGMFSIAIALYVFKNITKKEFWTPKVEKWIKISCWA
                     LNIGLAGMVFVTLMPVGYIQLKDALEHGYWHSRLTSFYEQPLVKAIMWGRMPWDIIFT
                     VGVIILVVIFIRGYRHLKPKYRV"
     gene            complement(6045..6746)
                     /gene="lrgB"
                     /locus_tag="RPH49_000005"
     CDS             complement(6045..6746)
                     /gene="lrgB"
                     /locus_tag="RPH49_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiholin-like protein LrgB"
                     /protein_id="HDY5123207.1"
                     /translation="MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSM
                     VFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIG
                     IGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILN
                     GVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVG
                     VVVVAVVPVFVAIFF"
     gene            complement(6739..7182)
                     /gene="lrgA"
                     /locus_tag="RPH49_000006"
     CDS             complement(6739..7182)
                     /gene="lrgA"
                     /locus_tag="RPH49_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiholin-like murein hydrolase modulator LrgA"
                     /protein_id="HDY5123208.1"
                     /translation="MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPASV
                     IGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIG
                     LIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD"
     gene            complement(7295..8035)
                     /locus_tag="RPH49_000007"
     CDS             complement(7295..8035)
                     /locus_tag="RPH49_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor LytR"
                     /protein_id="HDY5123209.1"
                     /translation="MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLI
                     NQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKP
                     FGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGI
                     GTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYT
                     YMVILTNGVKMQVGRSFMKDFKASIGLL"
     gene            complement(8038..9792)
                     /locus_tag="RPH49_000008"
     CDS             complement(8038..9792)
                     /locus_tag="RPH49_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDY5123210.1"
                     /translation="MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQL
                     CIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVG
                     LFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIV
                     MEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAV
                     QTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSD
                     HHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTL
                     KMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFF
                     FNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQ
                     ARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETAT
                     HVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFEST
                     SSGTTFWCVLPYERQEEE"
     gene            complement(10038..10712)
                     /gene="scdA"
                     /locus_tag="RPH49_000009"
     CDS             complement(10038..10712)
                     /gene="scdA"
                     /locus_tag="RPH49_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair di-iron protein ScdA"
                     /protein_id="HDY5123211.1"
                     /translation="MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAAVLEK
                     KNVDLNELLQRLNEVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVT
                     KLSKVHGPNHPYLVELKATYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVI
                     DDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHV
                     LFKKVS"
     gene            complement(10856..12577)
                     /gene="tarS"
                     /locus_tag="RPH49_000010"
     CDS             complement(10856..12577)
                     /gene="tarS"
                     /locus_tag="RPH49_000010"
                     /EC_number="2.4.1.355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(ribitol-phosphate)
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDY5123212.1"
                     /translation="MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCST
                     DQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETL
                     KDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRT
                     ALLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVS
                     PEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWI
                     NALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGK
                     LNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHS
                     RNKKHTMYVPLTVNANKQYRFNIMLEDIKADLPKEKIWDVFLEVQIGTEVFEVRVGNQ
                     RNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISMKLKGKNKII
                     LTGLDRGYVFEEGMASVVLKDDMVMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTA
                     HMTYSLK"
     gene            complement(12610..14298)
                     /locus_tag="RPH49_000011"
     CDS             complement(12610..14298)
                     /locus_tag="RPH49_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDY5123213.1"
                     /translation="MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRT
                     MKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQN
                     LKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDV
                     VVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSD
                     SRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIF
                     VDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYV
                     SSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVIL
                     FAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYF
                     VDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYE
                     SFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS"
     gene            complement(14320..15345)
                     /locus_tag="RPH49_000012"
     CDS             complement(14320..15345)
                     /locus_tag="RPH49_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDY5123214.1"
                     /translation="MINQVYQLVAPRQFEVTYNNVDIYSDYVIVRPLYMSICAADQRY
                     YTGSRDENVLSQKLPMSLIHEGVGEVVFDSKGVFNKGTKVVMVPNTPTEKDDVIAENY
                     LKSSYFRSSGHDGFMQDFVLLNHDRAVPLPDDIDLSIISYTELVTVSLHAIRRFEKKS
                     ISNKNTFGIWGDGNLGYITAILLRKLYPESKIYVFGKTDYKLSHFSFVDDVFFINKIP
                     EGLTFDHAFECVGGRGSQSAINQMIDYISPEGSIALLGVSEFPVEVNTRLVLEKGLTL
                     IGSSRSGSKDFQDVVDLYIQYPDIVDKLALLKGQEFEIATINDLTEAFEADLSTSWGK
                     TVLKWIM"
     gene            complement(15338..16054)
                     /locus_tag="RPH49_000013"
     CDS             complement(15338..16054)
                     /locus_tag="RPH49_000013"
                     /EC_number="2.7.7.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribitol-5-phosphate cytidylyltransferase"
                     /protein_id="HDY5123215.1"
                     /translation="MKYAGILAGGIGSRMGNVPLPKQFLDLDNKPILIHTLEKFILIN
                     DFEKIIIATPQQWMTHTKDTLRKFKISDERIEVIQGGSDRNDTIMNIVKHIESTNGIN
                     DDDVIVTHDAVRPFLTHRIIKENIQAALEYGAVDTVIDAIDTIVTSKDNQTIDAIPVR
                     NEMYQGQTPQSFNINLLKESYAQLSDEQKSILSDACKIIVETNKPVRLVKGELYNIKV
                     TTPYDLKVANAIIRGGIADD"
     gene            complement(16330..17499)
                     /locus_tag="RPH49_000014"
     CDS             complement(16330..17499)
                     /locus_tag="RPH49_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDY5123216.1"
                     /translation="MIKTTIKKLIEHSIYTTFKLLSKLPNKNLIYFESFHGKQYSDNP
                     KALYEYLTEHSDAQLIWGVKKGYEHIFQQHNVPYVKKFSMKWFLAMPRAKAWMINTRT
                     PDWLYKSPRTTYLQTWHGTPLKKIGLDISNVKMLGTNTQNYQDGFTKESQRWDYLVSP
                     NPYSTSIFQHAFHVSRDKILETGYPRNDKLSHKRNDTEYINGIKTRLNIPLDKKVIMY
                     APTWRDDEAIREGSYQFNVNFDIEALRQALDDDYVILLRMHYLVVTRIDEHDDFVKDV
                     SDYEDISDLYLISDALVTDYSSVMFDFGVLKRPQIFYAYDLDKYGDELRGFYMDYKKE
                     LPGPIVENQTALIDALKQIDETANEYIEARTVFYQKFCSLEDGKASQRICQTIFK"
     gene            complement(17928..19622)
                     /locus_tag="RPH49_000015"
     CDS             complement(17928..19622)
                     /locus_tag="RPH49_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDY5123217.1"
                     /translation="MTKTKQAIHIDNIYWERVQLYIEGHSEGVDLTSGQFVLRNLTET
                     KTLEANEMKIDGNTFICRFNVAILDDGYYLPMDKYLFVYHDQLEYIGQLNPNIIDQAY
                     AALNEEQIEEYNELTTQNGKANYVLANEAKVFRKGGVSQHTVYTITPEIASDVNEFVF
                     DIEITLPQEKSGVIATSAHWLHKQGHKASFESRSFLFKAIFNITKLLHIKRSKTILFT
                     SDSRPNLSGNFKYVYDELLRQKVDFDYDIKTVFKANITDRRKWRDKFRLPYLLGKADY
                     IFVDDFHPLIYTVRFRPSQEIIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKA
                     YVSSETDIPFYAEAFGIREENVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKV
                     ILFAPTFRGNGHGTAHYPFFKIDFERLARYCEKHNAVVLFKMHPFAKNRLNISREHRQ
                     YFIDVSDHREVNDILFVTDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEP
                     YESFVPGKIVQSFDALMDALDNEDYEVEKVVPFLDKHFKYQDGRSSERLVKDLFRR"
     gene            complement(19644..20669)
                     /locus_tag="RPH49_000016"
     CDS             complement(19644..20669)
                     /locus_tag="RPH49_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDY5123218.1"
                     /translation="MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRY
                     YTGRRDENVLRQKLPMSLVHEAVGEVVFDSTGVFEKGTKVVMVPNTPTEQHHIIAENY
                     LASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKS
                     IPLKTSFGIWGDGNLGYITAILLRKLYPEAKIYVFGKTDYKLSHFSFVDDIFTVNQIP
                     DDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTL
                     IGSSRSGSKDFEQVVDLYHKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGK
                     TVLKWTI"
     gene            complement(20662..21378)
                     /locus_tag="RPH49_000017"
     CDS             complement(20662..21378)
                     /locus_tag="RPH49_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDY5123219.1"
                     /translation="MIYAGILAGGIGSRMGNVPLPKQFLDIDNKPILIHTIEKFILVS
                     EFNEIIIATPAQWISHTQDILKKYNITDQRVKVVAGGTDRNETIMNIIDHIRNINGIN
                     NDDVIVTHDAVRPFLTQRIIKENIEVAAKYGAVDTVIEAIDTIVMSKDKQNIHSIPVR
                     NEMYQGQTPQSFNIKLLQDSYRALSSEQKEILSDACKIIVESGHPVKLVRGELYNIKV
                     TTPYDLKVANAIIQGDIADD"
     gene            complement(21906..22949)
                     /locus_tag="RPH49_000018"
     CDS             complement(21906..22949)
                     /locus_tag="RPH49_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDY5123220.1"
                     /translation="MKALKLYGVEDLRYEDNDKPVIESANDVIVKVRATGICGSVTSR
                     YKKMGPYIQGMPFGHEFSGVVDAIGSDVTHVKVGDKVTGCPAIPCYQCEYCLKGEYAR
                     CEKLFVIGSYEPGSFAEYVKLPAQNVLKVPDNVDYIEAAMVEPSAVVAHGFYKSNIQP
                     GMTVAVMGCGSIGLLAIQWARIFGAAHIIAIDIDAHKLDIATSLGAHQTINSKEEDLE
                     KFIENHYANQIDLAIESSGAKVTIGQILTLPKKGGEVVLLGIPYDDIEIDRVHFEKIL
                     RNELTVCGSWNCLSSDFPGKEWTATLHYMKTKDINVKPIISHFLPLEKGPETFDKLVN
                     KKERFDKVMFTIY"
     gene            complement(22973..23119)
                     /locus_tag="RPH49_000019"
     CDS             complement(22973..23119)
                     /locus_tag="RPH49_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123221.1"
                     /translation="MVESMLTFMLGPLRQITDFYMEHLLVSNSIVIAGYFATGIFKKK
                     KVVN"
     gene            complement(23121..24176)
                     /locus_tag="RPH49_000020"
     CDS             complement(23121..24176)
                     /locus_tag="RPH49_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDY5123222.1"
                     /translation="MKALVKTREGHGNLELLDKEVATPLDDKVKIKVHYAGICGTDIH
                     TYEGHYKVNFPVTLGHEFSGEIVEVGADVKDFKVGDRVTSETTFYICNECEYCESKDY
                     NLCNHRKGIGTQVDGAFTNYVIAREESLHHIPDEVSYQSAAMTEPLACAHHGVSKIQV
                     NSGDVAVVMGPGPIGLLVAQVLKSKGATVVVTGLDNDKVRLDKAEALHMDYVVNLQQT
                     DLKTYINGITDGYGADVVVECSGAVPAARQGLDILRKKGFYSQIGIFKDAEIPFDMEK
                     VIQKEITVVGSRSQKPADWEPSLRLMADGLVNAEALVTKIYDISKWDEAYQHLKSGEG
                     IKALLKPLDLDENEGEN"
     gene            complement(24194..25453)
                     /locus_tag="RPH49_000021"
     CDS             complement(24194..25453)
                     /locus_tag="RPH49_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDY5123223.1"
                     /translation="MSYFTDFVRGFLDLGATVILPVVIFLLGLFFRQKIGAAFRSGLT
                     IGVAFVGIFLVIDLLVKNLGPAAQAMVKNLGVSLNVIDVGWPATSSIAWASSVAAFII
                     PLGIIVNVVLLVTKVTKTMNVDIWNFWHYTFTAAMVYAVSGSIWQALLAAVIFQVICL
                     KVADWTAPMMSEFFDLPGVSIATGSTISYAPGIYLVKLLQKVPGLNKLDADPETIQKR
                     FGAFGESIFVGLILGLGIGVLAGYKPGDIINLGMSMAAVMVLMPRMVKILMEGLMPVS
                     ESARTWLNKRFGEREIYIGLDAAVALGHPAVISTALILVPITVLLAVILPGNQVLPFG
                     DLATIPFVVAFIVGAARGNIIHSVIVGTIMIAISLYIATDVAPIFTDMAKGTNVQMPK
                     GSSEISSIDQGGNIVNYLIFKLFSLFN"
     gene            complement(25680..25958)
                     /locus_tag="RPH49_000022"
     CDS             complement(25680..25958)
                     /locus_tag="RPH49_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDY5123224.1"
                     /translation="MKQVLVACGAGIATSTVVNNAIEEIAKEHNIKVDIKQIKITEVG
                     PYEDTADLLVTTAMTKKEYKFPVINARNFLTGIGIEETKQQILTELQK"
     gene            complement(25981..26448)
                     /locus_tag="RPH49_000023"
     CDS             complement(25981..26448)
                     /locus_tag="RPH49_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDY5123225.1"
                     /translation="MGQQLVHKENIMLNLSATDKESVLSQMSDVLFQNGFVKSTFKDA
                     VIDREKEFATGLPTHLCSVAIPHTDVEHINHRTIGVAVLEKEVPFIEMGTLDQQTEVK
                     IVFMLAMDKVDDQLKLLQQLMQIFQSEEKLEQILRTKDETILATLINDYLEYN"
     gene            complement(26433..28529)
                     /locus_tag="RPH49_000024"
     CDS             complement(26433..28529)
                     /locus_tag="RPH49_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDY5123226.1"
                     /translation="MNGDNQQILREIVLNPTIHGKELESIFGLSRRQLGYRIQKINLW
                     LEQEGYPKLERTSQGNFIVSSEIMTLFKRDVSEQQMLNGNNVIFSIETRRYYLMLMLF
                     SKENAMSLNHFSIDLQVSKNTVIHDINHVKEQLENHGLSLKYSRKHGYEIVGDEFEVR
                     RFFIKLIDQRLNHDITKSEVLKALNLTFEDIAYQKDKIKQVEQFLKSRFIDKSLSSLP
                     YVLCVIRRRIQSGHVMNPLNINYQYLRDTKEYQATEIMTQHEPDLPEAEKLYLTLHLL
                     STSVQWTDLQESDSISNLTMAIAQMIHHFEQITFINIKDKEKLSQQLLLHLTPAFYRI
                     KYNLTDRDELINPLQGNYQSLFHMVKQSCQSLTEYFGKSLPDNEIAYLTMLFGGSLRR
                     QDENFDGKIKAIIVCTQGTSVSQMMLYELRNLFPEIIFLDAISLRTFENYTLDYDIVF
                     SPMFVLTHKKLFITKVALSENEQRKLRKEVMKYINKESADIDKEINKLMALIERTTTV
                     NDITELRDGLEDFIANYNSISTINGSIVTQNKTLDLADLIPARHVKRIHHVENIDEAI
                     AKASDVLVANHFIDIKYIHEMQQVFDDSYMVIMQNIAIPHAYSEKHVHKTAMSMLILQ
                     EPIYMSDGTAIHIIVPIAAVDKVTHLRALLQLRDVAQDNDAIKRIIQSRKNSDVNEIL
                     KNYSNKEARENGWDSN"
     gene            complement(28654..28751)
                     /locus_tag="RPH49_000025"
                     /pseudo
     CDS             complement(28654..28751)
                     /locus_tag="RPH49_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498807.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28861..29796)
                     /locus_tag="RPH49_000026"
     CDS             complement(28861..29796)
                     /locus_tag="RPH49_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDY5123227.1"
                     /translation="MKRKIIMDCDPGHDDAIALILAGAIDSPLEILAVTTVAGNQSVD
                     KNTTNALNVLDIMGRQDIAVAKGADRPLIKSAAFASEIHGESGLDGPKLPSTPSRQAV
                     AMPASDMIINKVMTSDTPVTIVATGPLTNVATALIREPRIAEHIESITLMGGGTFGNW
                     TPTAEFNIWVDAEAAKRVFESGITINVFGLDVTHQVLADDLVIERFESINNPVAQFVV
                     ELLQFFKKTYKTHFNMDGGPIHDACTILYLLQPELFTMVPVNIDIEHQSPLTYGTMAV
                     DLNHVTGKPANAYFATAVDVEEVWNLIDYKLRTYE"
     gene            30158..31687
                     /locus_tag="RPH49_000027"
     CDS             30158..31687
                     /locus_tag="RPH49_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDY5123228.1"
                     /translation="MKSLFEKAQQFGKSFMLPIAILPAAGLLLGIGGALSNPNTVKAY
                     PILDITLLQNIFTLMSAAGSIVFQNLPVIFAIGVAIGLSRSDKGTAGLAALLGFLIMN
                     ATMNGLLTITGTLAKDQLAQNGQGMVLGIQTVETGVFGGITTGIMTAILHNKYHKVVL
                     PPYLGFFGGSRFVPIVTAFAAIFLGVLMFFIWPSIQAGIYHVGGFVTKTGAIGTFVYG
                     FILRLLGPLGLHHIFYLPFWQTALGGTLEVKGHLVQGTQNIFFAQLGDPDVTKYYSGV
                     SRFMSGRFITMMFGLCGAALAIYHTAKPEHKKVVGGLMLSAALTSFLTGITEPLEFSF
                     LFVAPILYVIHAFFDGLAFMMADIFNITIGQTFSGGFIDFLLFGVLQGNSKTNYLYVI
                     PIGIVWFCLYYIVFRFLITKFNFKTPGREDKAAAQQVEATERAQTIVAGLGGQDNIEI
                     VDCCATRLRVTLHQNDKVDKVLLESTGAKGVIQQGTGVQVIYGPHVTVIKNEIEELLG
                     D"
     gene            complement(32008..32961)
                     /locus_tag="RPH49_000028"
     CDS             complement(32008..32961)
                     /locus_tag="RPH49_000028"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDY5123229.1"
                     /translation="MNKFKGNKVVLIGNGAVGSSYAFSLVNQSIVDELVIIDLDTEKV
                     RGDVMDLKHATPYSPTTVRVKAGEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKI
                     FKSIVGEVMASKFDGIFLVATNPVDILAYATWKFSGLPKERVIGSGTILDSARFRLLL
                     SEAFDVAPRSVDAQIIGEHGDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQT
                     RDAAYDIIQAKGATYYGVAMGLARITEAIFRNEDAVLTVSALLEGEYDEEDVYIGVPA
                     VINRNGIRNVVEIPLNDEEQSKFAHSAKTLKDIMAESEELK"
     gene            complement(33272..33379)
                     /locus_tag="RPH49_000029"
                     /pseudo
     CDS             complement(33272..33379)
                     /locus_tag="RPH49_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498802.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            33534..34679
                     /locus_tag="RPH49_000030"
     CDS             33534..34679
                     /locus_tag="RPH49_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide dioxygenase"
                     /protein_id="HDY5123230.1"
                     /translation="MLTEQEKDIIKQTVPLLKEKGTEITSIFYPKMFKAHPELLNMFN
                     QTNQKRGMQSSALAQAVMAAAVNIDNLSVIKPVIMPVAYKHCALQVYAEHYPIVGENL
                     LKAIQDVTGLEENDPVIQAWAKAYGVIADVFIQIEKEIYDQMMWIGFKPFKITNIKQE
                     SEDIKSFTVETEEYDFSEFTPGQYITVDVSSDKLPYRAKRHYSIVSGDKNHLTFGVKR
                     DVTTEHEGEVSTILHDEIKEGDMINLAAPVGGFVLENTTEPQLFLGSGIGVTPLVAMY
                     EAASAKGLDTQMVQVAENEQHLPFKDNFNSIASHHDNAKLYTHLKDKQGYIGAEELKA
                     FLANKPEIYICGGTKFLQSMIEALKSLNYDMDRVHYETFIPRLSVAV"
     gene            34705..34878
                     /locus_tag="RPH49_000031"
     CDS             34705..34878
                     /locus_tag="RPH49_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123231.1"
                     /translation="MKLNQRYVKVFALYFVSIVTANIVVKNNNLIKTLIQTLAGYTVF
                     AVGLKYLTKRKNK"
     gene            35035..35391
                     /locus_tag="RPH49_000032"
     CDS             35035..35391
                     /locus_tag="RPH49_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDY5123232.1"
                     /translation="MTVDIGRIYDNKDNTDAIRILVDRVWPRGISKRTANLDYWLKDI
                     APSTELRQWFQHDPKLFGAFKEKYEKELRDQDVQKEAFEKLKDIVNQHNHVLLLYSAK
                     DTKHNQAVVLQQLLNT"
     gene            35589..37064
                     /locus_tag="RPH49_000033"
     CDS             35589..37064
                     /locus_tag="RPH49_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDY5123233.1"
                     /translation="MKFKRLATIFSAVLVLSGCGSMHSSGKDLNISLPLKTKSIAPYE
                     TDVPVKIGAAESLFKTNDQGKIEKVLVKSYHQPNDKTLDIELKDNIKFQNGQKLTAEK
                     VKSSLENSMKKSDLVKYSLPISSITAKGQKLTIKTNYAYPELVSELANPFMAIYDTDA
                     KSDVNQTPVGTGPYQIKDYKQSRKISLSNFKDYWQGKPKLDHITVTYQEDGNNRVRNL
                     ESQKDDLITDVPVNKVQDIENNQNLKVSKESGFRTSLLMYNHTNKKMTKSVREALDHI
                     IDRQGIADHIYQGYAKPATSPFNDKIPYIKEPKLTKQNIEQAKALLAKDGYTKEHPLK
                     IKLITYDGRPELSKIAQVLQSDAKKANIEIDIKSVDDIEGYLKDRSAWDATMYSFGTI
                     PRGDTGYFFNQAYKKDGAINKGDYNNSNVDDLINQLNHTVDIKERHNISNDIIKLSSR
                     DVPNSYIAYNDQIVAANSKVKNYKVTPEGIYLIDYRTTIER"
     gene            complement(37377..38519)
                     /locus_tag="RPH49_000034"
     CDS             complement(37377..38519)
                     /locus_tag="RPH49_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HDY5123234.1"
                     /translation="MSSASTQSTKTSDIHNESIDKQMEAKAHETAQNTDLKNEARSLF
                     DNATKSIGRLAGNDESLNLNLKDMFSEVFKPHTKNEADEIFIAGTAKTTPAICDISEE
                     WGKPWLFSRVFIAFTVTFIGLWVMAAIFNNTNAIPGLIFIGALTVPLSGLFFFYESNA
                     FKNISIFEVIIMFFIGGVFSLLSTMVLYRFVVFSDQFERFGSLTFFDAFLVGLVEETG
                     KALIIVYFVNKLKTNKILNGLLIGAAIGAGFAVFESAGYILNFALGENVPLLDIVFTR
                     AWTAIGGHLVWSAIVGAAIVIAKEQHGFEFKDIFDKRFLIFFLSAVGLHGIWDTSLTV
                     LGSDTLKIFILIVIVWILVFILMGAGLKQVNLLQKEFKEQQKKVDE"
     gene            complement(38742..39413)
                     /locus_tag="RPH49_000035"
     CDS             complement(38742..39413)
                     /locus_tag="RPH49_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDY5123235.1"
                     /translation="MRVNVLQHTPNEGVGYIGEWAKESGHEVYIYHPYMNDGVLPLAE
                     ETDMLVILGGPMNPDDEMPWIQSERELILVLMAQNKPIYGACFGAQQISKALGYAVLK
                     SPVKEVGWDDVYLESEIIPNIPSRLKALHWHEDMFQIPQQAELLFSGNHIRNQGFIID
                     HHVIGLQFHFEPGPDDVREIVLNDAQYINHSILEQSAEDILAFEVPKQNRQAIFRILD
                     FITQA"
     gene            39772..41349
                     /locus_tag="RPH49_000036"
     CDS             39772..41349
                     /locus_tag="RPH49_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDY5123236.1"
                     /translation="MEVTCLKQITWHDLQHIIKDGDVIGLPALAVANLPAEVLRAVLA
                     QHDTYHTPNDLTFILANDIHSLGAAPDLDDFIERRMIKRVIMSILTASSKTAQAMKNN
                     DIEAYFLPQGIIATHYRQSNQLLPGVITKIGLNTAVDPRYGGGKVNTRTTDDLVSLVT
                     INDETYLHYTFPSVDVALLRGTYADQQGNIYLTQEAYLSECYHVALNTKANHGKVIVQ
                     VKALVDDYQLKPNEVVIPGNLVDYVYVTEDEKNHRQVIQSHYLPALSGEERIDGIPEP
                     ALPFNSRKLILRRAAQFLTYGDTISIGYGINNELSNLLHEECVEHDVQPILDVGIFGG
                     FVGSREHFGMNYNADVRMPHDRAWDFIYNNGVSVAYLSFAEVDQHGNVNVSYFNDRLN
                     GCGGFIDITQSVNKIIFSGTFVAGSHVSCHNQRLNIETEGQNQKFVSDVSHIDFNAQY
                     SQSLEQEVYFVTDRAVFELTNQGLKLIEIAPGLDLHKDILNQMAFKPIIADHLKLIDT
                     SIYKEKWGQLKQSIHKV"
     gene            41375..42880
                     /locus_tag="RPH49_000037"
     CDS             41375..42880
                     /locus_tag="RPH49_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl--CoA ligase"
                     /protein_id="HDY5123237.1"
                     /translation="MNFDWIKTRSDFDDDKPAVIDHAKQTSWTYQQLNARADNMAHYL
                     TSQGVKKGDVIGIFAPNDIAILDLLFACFKTGAVFLPLNWRLNPKEIAAIVEDAQLKL
                     LFYAEKHLSSLTDIDQNLLHMDIDVAQYDEIVNPDYHQPFQATPVEPQDLAALIYTSG
                     TTGSPKGVMFSYESFVHNGANLELTYKFNSNYITIVSTPMFHVLGFNDTVLPVLMSGG
                     TLILQRYFNGEELNDMIAQYHPTFIIMIPTMYYSTLRASNFNPENFKAMDYIIQGGSQ
                     PLPSIQAAFKQYGINIINGYGLTEAPLVLVNTPENSKRKPMSIGKAVMFVDARILDDN
                     GEEVPTGEIGELAIKAKNVTPGYWNKPAETAKAFHGRYLLTGDLAKMDDDGDIFIIDR
                     KKELIITGGENVLPSEVENALAEHPLVDRCVVVGYDHPKYGESIAAAIILREDEPHYA
                     EILDQHMRSRLAGYKVPRMYVPVTHMPLNSTQKPDKLAIRQMMNDKVSQTL"
     gene            42992..44203
                     /locus_tag="RPH49_000038"
     CDS             42992..44203
                     /locus_tag="RPH49_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="HDY5123238.1"
                     /translation="MTFEKETVLKTLFPEDVLSIAKGLTDGEVEFLQQVDSLLESKYR
                     ENINQHWIDATVPEDFFKNLGELNYFNNPLLYKDRPNAKMPSQLFQFFMSYLLARFDI
                     SLATLLGVHQGLGHNTFYFGGSKEQIAKYVPKLQSHELRTCFALTEPEHGSDVAGGLE
                     TVAERQGDTWVINGEKKWIGGAHVSDVIPVFAVNKETGKPHCFVVRPEQDGVDIEVID
                     NKIALRIVPNALIKLTNVKVDEADRLQNITSFKDIAKILYSTRAGVAYMATGGMAGAL
                     RATLDYVTERKQFGKPISKYQLIQEKLAMMQGNLAQAMATCAQLANMQAHGEYDEVAT
                     STAKMMNALRLRETVAMGRGITGGNGILADDYDIARFFSDAEAIYTYEGTHEINALVI
                     GRALTGDSAFV"
     gene            44390..46651
                     /locus_tag="RPH49_000039"
     CDS             44390..46651
                     /locus_tag="RPH49_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDY5123239.1"
                     /translation="MTINKVTVLGAGTMGAQLAALFVNAGLKVKLLDIVVDKNDPNLI
                     AKKSYDKITDKKRPLLFDLNLASHLTYGNFDDDLVNDDADLYIEAVKEDIEIKHAVWQ
                     QVLQHAKEDALFATNTSGIPINAIAQVFNEKDQERFFGLHFFNPPRIMKLVELIPTSH
                     TKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDIMYRAEQHKLSIVDVD
                     ALTGQAIGRPKTGTYALSDLVGLDIAVSVIKGMQQVPEETPYFHDVKIVNTLFDNGAL
                     GRKTKQGFYKKDKETKARLVYDVEKQDYVPVSQPQLPILNEFNKDLAHNLDVIFNAQD
                     EAGLFLWETLRNNFYYSAINVPKATDDFRDIDRALVWGFNWKLGPFQLWDAMGYVRVK
                     KRMEDEFGDLPQWISDLDGGFYKKDETIEYATPVSHFVKDELWDKGDAKLSVTHDDQL
                     LLKLQSKNNVITDEFNDALVDAIDLLENDHYTSMVIYADGNNFSVGANLFLMKKAHED
                     GLVDDVVAQSIDKLHYSFNRLKYSLKPVVTAVQGRALGGGCELVLYSPIVVAASETYI
                     GLVEAGVGLLPSGGGLAEMADRILRTSHKFDDKQASMTKVLTNIAFAKVSTNAFEARR
                     YGYLRDTDTIIFNTAQRVEVALKRAKYEAETNYIPNPRHQYIALGEDFKAFIQGQLDA
                     QRRGHFISDHDYHIALNIATILAGGDLPRNTFINQRYIQSLEKIGFIDLLKSKKSYER
                     IAHMLKTGKPLRN"
     gene            46681..47865
                     /locus_tag="RPH49_000040"
     CDS             46681..47865
                     /locus_tag="RPH49_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDY5123240.1"
                     /translation="MQEAYIVAYGRSAAAKAKQGALFHERPDDVAAKVLQGVLKRIDG
                     KFNKNMIEDVIVGTAFPEGLQGQNIARTIALRTGLSDTVPGQTVNRYCSSGLQTIAIA
                     ANQIMAGQGDILVAGGVELMSAVPMGGNEPTNNPTLQYDDIGASYPMGLTAENVASQF
                     DVSREDQDAYAVRSHQRAYDAQRDGRFKNEIIPIQVNSVEYTNAGPKVHTNIFDQDEF
                     IRPDTTMEALAKLRTVFKADGTVTAGTSAPLSDGAGFVVLMSGDKVKELGVTPIARFV
                     GYKAVGVDPKIMGIGPAYAIPEVLSLSNLSVEDIDLIELNEAFASQTIASIKEVGLDI
                     SRTNVNGGAIALGHPLGATGAMLTARLLNEMGRRPDSRYGMVTMCIGVGMGAAAIFEY
                     VR"
     gene            48179..48286
                     /locus_tag="RPH49_000041"
     CDS             48179..48286
                     /locus_tag="RPH49_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123241.1"
                     /translation="MCVRTRLVSSSSVRLSKAIIIAVIVVYHLDVRGLF"
     gene            complement(48468..50438)
                     /gene="coa"
                     /locus_tag="RPH49_000042"
     CDS             complement(48468..50438)
                     /gene="coa"
                     /locus_tag="RPH49_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylocoagulase"
                     /protein_id="HDY5123242.1"
                     /translation="MKKQIISLGALAVASSLFTWDNKADAIVTKDYNGKSQVKKESKN
                     GTLIDSRYYWEKIEALEKQFSSALALTDEYQYGGNEYKEAKDKLMERILGEDQYLLKK
                     KIDEYDYYKKWYKATYPNDNSKMYSFHKYNVYYLTMNEYNEISNSLKDAVEKFNNEVR
                     DIQSKNEDLKPYDENTEKQETDKIYEFVSEIDTVFAAYYSHEKFGIHAKELRAKLDII
                     LGDVHNPNRITNERIKKEMMEDLNSIVDDFFMETNQNRPTTIKKYDPNIHDYTKKKEN
                     KENFDKLVKETREAVEKADESWKNKTVKKYEETVTKSPFVKEEKKVEEPQLPKVGNQQ
                     EVKTTAGKAEETTQPLVKIPQGTITGEIVKGPDYPTMENKTLQGEIVQGPDFPTMEQN
                     RPSLSDNYTQPTTTNPILEGLEGSSSKLEIKPQGTESTLQGTQGESSDIEVKPQATET
                     TEASQYGPRPQFNKTPKYVKYRDAGTGIREYNDGTFGYEARPRFNKPSETNAYNVTTN
                     QDGTVTYGARPTQNKPSKTNAYNVTTHANGQVSYGARPTYKKPSETNAYNVTTHANGQ
                     VSYGARPTQNKASETNAYNVTTHANGQVSYGARPTQNKPSKTNAYNVTTHGNGQVSYG
                     ARPTYKKPSETNAYNVTTHADGTATYGPRVTK"
     gene            50628..50972
                     /locus_tag="RPH49_000043"
     CDS             50628..50972
                     /locus_tag="RPH49_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN family protein"
                     /protein_id="HDY5123243.1"
                     /translation="MTTQMKIKTYLVAGIKAALLDTTGIKLASKSETTSHTYQHQALV
                     DQLYELIANTDLNKLSYLNLDAFQKRDILAAHYIAKSAIRTKNLDQMTKAKHRLESIY
                     DSISNPLHSQKN"
     gene            complement(51136..52899)
                     /locus_tag="RPH49_000044"
     CDS             complement(51136..52899)
                     /locus_tag="RPH49_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase
                     membrane domain-containing protein"
                     /protein_id="HDY5123244.1"
                     /translation="MKRISKDIWAVFKLLYQNKGRFSINALLLQLIMIFISSTYLILL
                     FNMMLKVAGQSQLTINNWMEIVSHPASVILLIIFILSVAFLIYVEFSLLVYMVYAGFD
                     RQIITFKSIFKNAFVNVRKLIGVPVIFFVIYLMLMIPIANLGLSSVLTKNIYIPKFLT
                     EELMKTTKGIIIYGTFMIAVFILNFKLIFTLPLTILNRQSLFKNMRLSWQITKRNKFR
                     LVIEIVILELIIGAILTLIISGATYLAICVDEEGDKFLVSSILFVVLKSALFFYYLFT
                     KLSLISVLVLHLKQENVLDQPGLEFKYPKPKRKSRFFIISMVLAVTCFIGYNMYLLYN
                     NTINTNISIIGHRGFEDKGVENSIPSLKAAAKANVEYIELDTIMTKDKQFVVSHDNNL
                     KRLTGVNKNISESNFKDVVGLKMRQNGHEAKLVSLDEFIETAKQSNVKLLVELKPHGK
                     EPADYTQRVIDILKKHGVEHQYRVMSLDYDVMTKLKKEAPYLKCGYIIPLQFGHFKET
                     SLDFFVIEDFSYSPRLVNQAHMENKEVYTWTINGEEDLTKYLQTNVDGIITDDPALAD
                     QIKEEKKDETYFDRSIRILFE"
     gene            complement(53235..53990)
                     /gene="pflA"
                     /locus_tag="RPH49_000045"
     CDS             complement(53235..53990)
                     /gene="pflA"
                     /locus_tag="RPH49_000045"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDY5123245.1"
                     /translation="MLKGHLHSVESLGTVDGPGLRYILFTQGCLLRCLYCHNPDTWKI
                     SEPSREVTVDEMVNEILPYKPYFDASGGGVTVSGGEPLLQMPFLEKLFAELKENGVHT
                     CLDTSAGCANDTKAFQRHFEELQKHTDLILLDIKHIDNDKHIRLTGKPNTHILNFARK
                     LSDMKQPVWIRHVLVPGYSDDKDDLIKLGEFINSLDNVEKFEILPYHQLGVHKWKTLG
                     IAYELEDVEAPDDEAVKAAYRYVNFKGKIPVEL"
     gene            complement(54013..56262)
                     /gene="pflB"
                     /locus_tag="RPH49_000046"
     CDS             complement(54013..56262)
                     /gene="pflB"
                     /locus_tag="RPH49_000046"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDY5123246.1"
                     /translation="MLETNKNHATAWQGFKNGRWNRHVDVREFIQLNYTLYEGNDSFL
                     AGPTEATSKLWEQVMQLSKEERERGGMWDMDTKVASTITSHDAGYLDKDLETIVGVQT
                     EKPFKRSMQPFGGIRMAKAACEAYGYELDEETEKIFTDYRKTHNQGVFDAYSREMLNC
                     RKAGVITGLPDAYGRGRIIGDYRRVALYGVDFLMEEKMHDFNTMSTEMSEDVIRLREE
                     LSEQYRALKELKELGQKYGFDLSRPAENFKEAVQWLYLAYLAAIKEQNGAAMSLGRTS
                     TFLDIYAERDLKAGVITESEVQEIIDHFIMKLRIVKFARTPDYNELFSGDPTWVTESI
                     GGVGIDGRPLVTKNSFRFLHSLDNLGPAPEPNLTVLWSVRLPDNFKTYCAKMSIKTSS
                     IQYENDDIMRESYGDDYGIACCVSAMTIGKQMQFFGARANLAKTLLYAINGGKDEKSG
                     AQVGPNFEGINSEVLEYDEVFKKFDQMMDWLAGVYINSLNVIHYMHDKYSYERIEMAL
                     HDTEIVRTMATGIAGLSVAADSLSAIKYAQVKPIRNEEGLVVDFEIEGDFPKYGNNDD
                     RVDDIAVDLVERFMTKLRSHKTYRDSEHTMSVLTITSNVVYGKKTGNTPDGRKAGEPF
                     APGANPMHGRDQKGALSSLSSVAKIPYDCCKDGISNTFSIVPKSLGKEPEDQNRNLTS
                     MLDGYAMQCGHHLNINVFNRETLIDAMEHPEEYPQLTIRVSGYAVNFIKLTREQQLDV
                     ISRTFHESM"
     gene            56850..57818
                     /locus_tag="RPH49_000047"
     CDS             56850..57818
                     /locus_tag="RPH49_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDY5123247.1"
                     /translation="MKSKIYILLLFLIFLSACANTRHSESDKNVLTVYSPYQSNLIRP
                     ILNDFEKQEHVKIEIKHGSTQVLLSNLHNEDLSERGDVFMGGVLSETIDHPEDFVPYQ
                     DTSVTQQLEDYRSNNKYVTSFLLMPTVIVVNSDLQGDITIRGYQDLLKPILKGKIAYS
                     NPNTTTTGYQHMRAIYSMHHRVSDVHQFQDHAMQLSKTSKVIEDVAKGKYYAGLSYEQ
                     DARTWKNKGYPVSIVYPIEGTMLNVDGIALVKNAHPHPKRKKLVQYLTSRSVQQRLVA
                     EFDAKSIRKDVSEQSDQSIENLKNIPLIPKSKLPDIPHHKFLEMIQ"
     gene            57815..59371
                     /locus_tag="RPH49_000048"
     CDS             57815..59371
                     /locus_tag="RPH49_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDY5123248.1"
                     /translation="MTAYKPYRHQLRRSLFASTIFPVFLVLIIGLVSFYAIYIWIEHR
                     TIHQHVDESQSSLHHTEKQIQTFITQHNNSFQELDLTNHHDVTATKRELLKLIHQQPA
                     TLYYELSGPNQFITNNYEHLNTKNMYLFSTHQLKFKNSTYMLKIYMANTPRLIEIKKD
                     SRQFALIVDQYDNILYANDDRFTIGEKYRPQQFGFMNESVKLNHADHRLIIYKDIHEN
                     IEDGITLLIVMAVVLVLLVIFGFISADNMAKRQTKDIETIIQKIYYAKNRHLGTYTPL
                     KNNSELEEINNYIYDLFESNEQLIHSIEHTERRLRDIQLKEIERQFQPHFLFNTMQTI
                     QYLITLSPKLAQTVVQQLSQMLRYSLRTNSHTVELNEELNYIEQYVAIQNIRFDDMIK
                     LHIESSEEARHQTIGKMMLQPLIENAIKHGRDTESLDITIRLTLARQNLHVLVCDNGI
                     GMSSSRLQYVRQSLNNDVFDTKHLGLNHLHNKAMIQYGSHARLHIFSKRNQGTLICYK
                     IPLSRGNVDV"
     gene            59364..60122
                     /locus_tag="RPH49_000049"
     CDS             59364..60122
                     /locus_tag="RPH49_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5123249.1"
                     /translation="MFKVVICDDERIIREGLKQIIPWGDYHFNTIYTAKDGVEALSLI
                     QQHQPELVITDIRMPRKNGVDLLNDIAHLDCNVIILSSYDDFEYMKAGIQHHVLDYLL
                     KPVDHAQLEVILGRLVRTLLEQQSQNGRSLASCHDAFQPLLKVEYDDYYVNQIVDQIK
                     QSYQTKVTVSDLIQHIDVSESYAMRTFKDHVGITIVDYLNRYRILQSLQLLDRHYKHY
                     EIADKVGFSEYKMFSYHFKKYLQMSPSDYCKQAK"
     gene            complement(60481..61860)
                     /gene="uhpT"
                     /locus_tag="RPH49_000050"
     CDS             complement(60481..61860)
                     /gene="uhpT"
                     /locus_tag="RPH49_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDY5123250.1"
                     /translation="MNFFDIHKIPNKGIPLSVQRKLWLRNFMQAFFVVFFVYMAMYLI
                     RNNFKAAQPFLKEEIGLSTLELGYIGLAFSITYGLGKTLLGYFVDGRNTKRIISFLLI
                     LSAITVLIMGFVLSYFGSVMGLLIVLWGLNGVFQSVGGPASYSTISRWAPRTKRGRYL
                     GFWNTSHNIGGAIAGGVALWGANVFFHGNVIGMFIFPSVIALLIGIATLFIGKDDPEE
                     LGWNRAEEIWEEPVDKENIDSQGMTKWEIFKKYILGNPVIWILCVSNVFVYIVRIGID
                     NWAPLYVSEHLHFSKGDAVNTIFYFEIGALVASLLWGYVSDLLKGRRAIVAIGCMFMI
                     TFVVLFYTNATSVMMVNISLFALGALIFGPQLLIGVSLTGFVPKNAISVANGMTGSFA
                     YLFGDSMAKVGLAAIADPTRNGLNIFGYTLSGWTDVFIVFYVALFLGMILLGIVAFYE
                     EKKIRSLKI"
     gene            62093..62587
                     /locus_tag="RPH49_000051"
     CDS             62093..62587
                     /locus_tag="RPH49_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002454321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HDY5123251.1"
                     /translation="MILSILLIFFCIRLVSLKISINHSKQLKADGAVEYGVKNSKFLA
                     ITHVLIYVLAGVEAFINKDTFSFANGIGLVILIFAYIMLFMVIKTLGGIWTLKLFILP
                     NHPIIKSGLYKITKHPNYFLNIIPELIGVLLLTHATYTTILLVPYAYFLYVRIKQEEK
                     LMNI"
     gene            complement(62948..63916)
                     /locus_tag="RPH49_000052"
     CDS             complement(62948..63916)
                     /locus_tag="RPH49_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDY5123252.1"
                     /translation="MKIGVFSVLFYDKNFEDMLDYVAESGLDMIEVGTGGNPGDKFCK
                     LDELLENEDKRQAFMKSITDRGLQISGFSCHNNPISPDPIEAKEADETLRKTIRLANL
                     LDVPVVNTFSGIAGSDDTAKKPNWPVTPWPTAYSEIYDYQWNEKLIPYWQDLAEFAKE
                     QDVKIAIELHAGFLVHTPYTMLKLREATNEYIGANLDPSHLWWQGIDPIAAIRILGQA
                     NAIHHFHAKDTYINQENVNMYGLTDMQPYGNVATRAWTFRTVGYGHSPYVWADIISQL
                     IINGYDYVLSIEHEDPIMSVEEGFQKACQTLKSVNIYDKPADMWWA"
     gene            complement(63971..65011)
                     /locus_tag="RPH49_000053"
     CDS             complement(63971..65011)
                     /locus_tag="RPH49_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDY5123253.1"
                     /translation="MTKLKVGVIGVGGIAQDRHIPALLKLKDTVSLVAVQDINTVQMI
                     DVAKRFNIPQAVETPSELFKLVDAVVICTPNKFHADLSIEALNHGVHVLCEKPMAMTT
                     EECDRMIEAANKNHKLLTVAYHYRHTDVAMTAKKAIEAGVVGKPLVARVQAMRRRKVP
                     GWGVFTNKALQGGGSLIDYGCHLLDLSLWLLGKDMVPHEVLGKTYNQLSKQPNQINDW
                     GTFDHTKFDVDDHVTSYMTFANRASMQFECSWSANIKEDKVHVSLSGEDGGINLFPFE
                     IYEPRFGTIFESKANVEHNEDIAGERQARNFVNACLGIEEIVVKPEEARNVNALIEAI
                     YRSDLDNKSIQL"
     gene            complement(65036..66112)
                     /locus_tag="RPH49_000054"
     CDS             complement(65036..66112)
                     /locus_tag="RPH49_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDY5123254.1"
                     /translation="MTIKVGIIGCGGIANGKHMPSLQKVENVEMIAFCDVDISKAASA
                     AEAYGTDNAKVYDDYKALLKDDTIDVIHVCTPNDSHCEITVAGLHAGKHVMCEKPMAK
                     TTAEAQKMIDTAKSTGKKLTIGYQNRFRPDSQFLHQAAQRGDLGDIYFGKAHAIRRRA
                     VPTWGVFLDEEAQGGGPLIDIGTHALDLTLWMMDNYEPESVMGSTFHKLNKQHHAANA
                     WGSWNPDEFTVEDSAFGFIKMKNGATIILESAWAINSLEVDEAKCSLSGTKAGADMKD
                     GLRIHGEDMGTLYTKHVELENKGVDFYEGNEVDEAEEEAKAWIDAVVNDTEPVVKPEQ
                     AMVVTKILEAIYQSAKSGKAIYFE"
     gene            complement(66186..67025)
                     /locus_tag="RPH49_000055"
     CDS             complement(66186..67025)
                     /locus_tag="RPH49_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDY5123255.1"
                     /translation="MTKKKNILKAIGIYSFIAMMFVIILYPLLWTFGISLNPGTNLYG
                     AKMIPDNATFKNYAFLLFDDSSQYLTWYKNTLIVASANALFSVIFVTLTAYAFSRYRF
                     VGRKYGLITFLILQMFPVLMAMVAIYILLNTIGLLDSLFGLTLVYIGGSIPMNAFLVK
                     GYFDTIPKELDESAKIDGAGHMRIFLQIMLPLAKPILAVVALFNFMGPFMDFILPKIL
                     LRSPEKFTLAVGLFNFINDKYANNFTVFAAGAIMIAVPIAIVFLFLQRYLVSGLTTGA
                     TKG"
     gene            complement(67027..68295)
                     /locus_tag="RPH49_000056"
     CDS             complement(67027..68295)
                     /locus_tag="RPH49_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDY5123256.1"
                     /translation="MTKRNPKLAALLSVIPGLGQFYNKRPIKGTIFFIFFISFISVFY
                     SFLNIGFWGLFTLGTVPKLDDSRVLLAQGIISILLVAFAIMLYVINILDAYRNAERFN
                     RNEEIKDPKARMVATWDKTFPYLLISPGTFLLIFVVVFPLIFMFGVAFTNYNLYNAPP
                     RHTLEWVGLDNFKTLFTIGVWRKTFFSVITWTLVWTLVATTLQIALGLFLAIIVNHPV
                     VKGKKFIRTVLILPWAVPSFVTILIFVALFNDEFGAINNDILQPLLGVAPAWLSDPFW
                     AKVALIGIQVWLGFPFVFALFTGVLQSISSDWYEAADMDGASSWQKFRNITFPHVIYA
                     TAPLLIMQYAGNFNNFNLIYLFNKGGPPVSGQNAGSTDILISWVYNLTFEFNNFNMGA
                     VVSLIIGFIVAIVAFIQFRRTSTFKDEGGL"
     gene            complement(68298..69569)
                     /locus_tag="RPH49_000057"
     CDS             complement(68298..69569)
                     /locus_tag="RPH49_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDY5123257.1"
                     /translation="MSKILKCITLAVVMLLIVTACGPNRSKEDIDKALNKDNSKDKPN
                     QLTMWVDGDKQMAFYKKITDQYTKKTGIKVKLVNIGQNDQLENISLDAPVGKGPDIFF
                     LAHDNTGSAYLQGLAAEIKLSKDELKGFNKQALKAMNYDNKQLALPAIVETTALFYNK
                     KLVKNAPQTLEEVEANAAKLTDSKKKQYGMLFDAKNFYFNYPFLFGNDDYIFKKNGSE
                     YDIHQLGLNSKHVVKNAERLQKWYDKGYLPKAATHDVMIGLFKEGKVGQFVTGPWNIN
                     EYQETFGKDLGVTTLPTDGGKPMKPFLGVRGWYLSEYSKHKYWAKDLMLYITSKDTLQ
                     KYTDEMSEITGRVDVKSSNPNLKVFEKQARHAEPMPNIPEMRQVWEPMGNASIFISNG
                     KNPKQALDEATNDITQNIKILHPSQNDKKGD"
     gene            complement(69582..70679)
                     /gene="ugpC"
                     /locus_tag="RPH49_000058"
     CDS             complement(69582..70679)
                     /gene="ugpC"
                     /locus_tag="RPH49_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDY5123258.1"
                     /translation="MAELKLEHIKKTYDNNNTVVKDFNLHITDKEFIVFVGPSGCGKS
                     TTLRMVAGLESITSGDFYIDGERMNDVEPKNRDIAMVFQNYALYPHMTVFENMAFGLK
                     LRKVNKKEIEQKVNEAAEILGLTEYLGRKPKALSGGQRQRVALGRAIVRDAKVFLMDE
                     PLSNLDAKLRVQMRTEILKLHKRLNTTTIYVTHDQTEALTMASRIVVLKDGDIMQVGT
                     PREIYDAPNCIFVAQFIGSPAMNMLNATVEMDGLKVGTHHFKLHNKKFEKLKAAGYLD
                     KEIILGIRAEDIHEEPIFIQTSPETQFESEVVVSELLGSEIMVHSTFQGMELISKLDS
                     RTQVMANDKITLAFDMNKCHFFDEKTGNRIV"
     gene            complement(71062..71640)
                     /locus_tag="RPH49_000059"
     CDS             complement(71062..71640)
                     /locus_tag="RPH49_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDY5123259.1"
                     /translation="MTKRPKRILATIIIFLSLLFTIIYIDDIQKWFNQYTDKLTQNHK
                     GQGHSKWEDFFRGSRITETFGKYQHSPFDGKHYGIDFALPKGTPIKAPTNGKVTRFFN
                     NELGGKVLQIAEDNGEYHQWYLHLDKYNVKVGDRVKAGDIIAYSGNTGKQTTGAHLHF
                     QRMKGGVGNAYAEDPKPFIDQLPDGERSLYDL"
     gene            71849..72475
                     /locus_tag="RPH49_000060"
     CDS             71849..72475
                     /locus_tag="RPH49_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDY5123260.1"
                     /translation="MAKVLYITAHPFNELVSNSMAAGKAFIETYQQQHPDDEVKHIDL
                     FETYIPVIDKDVLTGWGKMSNGETLTDDEQMKVSRLSDILEEFLSADKYVFVTPMWNL
                     SFPPVVKAYIDAISIAGKTFKYSAEGPQGLLTDKKVLHIQSRGGYYTEGPAADFEMGD
                     RYLRTIMTFLGVPSYETIIIEGHNAEPHKTEEIKATSINNAEKLATTF"
     gene            72665..73438
                     /locus_tag="RPH49_000061"
     CDS             72665..73438
                     /locus_tag="RPH49_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5123261.1"
                     /translation="MKAHKIFWLNLAAIIIISIVVSGGMFLAMKWEQIHLKDGLKKVL
                     STYPIKNLETLYEIDGHDNPHYENNDQDTWYIESSYSVVGSDELFKEDRMLLKVDKNT
                     HKITGEYDTTTNDRKNATDSTYKSYPVKVVNNKIVFTKDVKDPTLKQKIENNQFLIQN
                     GDLTSILNSNDLKVTHDPTTDYYNLSGKLSNDNPNVKQLKRRYNIPRNASTKVELKGM
                     SDLKGNNHQDQKLYFYFSSPGKNQIIYTESLTYNKLSEH"
     gene            complement(73751..75757)
                     /gene="ggt"
                     /locus_tag="RPH49_000062"
     CDS             complement(73751..75757)
                     /gene="ggt"
                     /locus_tag="RPH49_000062"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDY5123262.1"
                     /translation="MVINLNDKQTKTSKEGLISVSHPLAAKIGKDVLDQGGNAMDAVI
                     AIQLALNVVEPFASGIGGGGYLLYYEQSTGSITAFDARETAPAHVDKQFYLDDSGEYK
                     SFFDMTTHGKTVAVPAIPKLFDYIHKRYAKLSLEDLINPAIELAIEGHSANWATEKYS
                     RQQHARLTKYHETAQVFTHENQYWREGDWIVQPELGKTFQILREQGFNAFYKGDIAKQ
                     LVNVVKACGGTITLEDLAKYDIQIKAPISATFKDYDIYSMGPSSSGGITVIQILKLLE
                     HVDLPSMGPRSVDYLHHLIQAMHLAYSDRAQYLADDNFHEVPVQSLIDDDYLKARSTL
                     IDSNKANIDIEHGVVSDCISHTDVEENHTETTHFCVIDKEGNIASFTTSIGMIYGSGI
                     TIPGYGVLLNTTMDGFDVVDGGINEIAPYKRPLSNMAPTIVMYHGKPILTVGAPGAIS
                     IIASVAQTLINVLVFGMDIQQAIDEPRVYSSHPNRIEWEPQFSQSTILALIARGHAME
                     HKPDAYIGDVHGLQVDLNTRDASGGADDTREGTVIGGDVLSIRKEPLPSPKIYDNDTH
                     RVYFNDMQLPLYAEQVRWMYDKYWVDESVIRIIFPEVSVHIEDLRSYEIAGKNYIDIA
                     WLARKKGYQVTLKDDSLYLTDETYHSVKANTNAYYRYDRDSITR"
     gene            complement(75795..77570)
                     /locus_tag="RPH49_000063"
     CDS             complement(75795..77570)
                     /locus_tag="RPH49_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5123263.1"
                     /translation="MKKIISIAIIVLALVLSGCGVPTKSEVAQKSSKVEVKGERPTIH
                     FLGQASYENDMNIVKDQLENAGFNVKMNIQPDYGSYRTQRQAGNYDIQIDDWMTVFGD
                     PNYAMTALFSSTGSNSLLKDKHVDQLLNKASTQNEADVKQTYKQIEDEVVFDKGYMAP
                     LYGSKKNLVYDNKVLDKNSVGLPNSRALIWQQFDYNNSRERDTRPLVMTQQDGEIPTL
                     DPIRSIAPSVYSINMNMYTRLLLLDENDHLTTKGSLSRDYAVNKDNKAFYFLLRDDDY
                     FAKVVNGQARNTGERVSAEDVKFSLDRARDKKSVPNNNTYNMHKHINDIKILKDEDID
                     QLRKEKDKDDKSIYDKLIKAYNVKSLTTDGQKVNNKDGIYQIVKITTDQSMPREVNYL
                     THSSAGILSKKFVNQVNQEYPKGYGDSSTIPANSDGKNALYASGAYIMTQKNAYQATF
                     QRNPGFNETEKGSYGPAKIKNITLKFNGDPNNALSELRNHSIDMLADVNQKHFDLIKS
                     DKNLSIIRKNGRKSVFLMLNIKKGIFKTHPNLRQAVVNAINQDQFIKFYRGDKFKIAS
                     PITPLVDTGNEQRQDLEKVEKAINQ"
     gene            complement(77587..78750)
                     /locus_tag="RPH49_000064"
     CDS             complement(77587..78750)
                     /locus_tag="RPH49_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123264.1"
                     /translation="MVKLTTKIASLKLFASYAIATYILVILTSALNLFKGYVADTFYI
                     AETLLIVLTIILIIILTTEQTWKHHDLWRRIVEVLLLLMTLTGNVFTLLMFVSIRRYE
                     RTSQIHSYNGWESFIRKTTRHRIAIIGLLILVYMLTLSIVSQFTFDTTLATKNQFNAL
                     LHGPSLAYPFGTDDFGRDLFTRVVVGTKLTFSISIISVVIAVIFGVLLGTIAGYFNHI
                     DNLIMRILDVVFAIPSLLLAVAIIASFGASIPNLIIALSIGNIPSFARTMRASVLEIK
                     RMEYVDAARITGENTWNIIWRYILPNAIAPMIVRFSLNIGVVVLTTSSLSFLGLGVAP
                     DVAEWGNILRTGSNYLETHSNLAIVPGVCIMFVVLAFNFIGDAVRDALDPRIH"
     gene            complement(78756..80234)
                     /locus_tag="RPH49_000065"
     CDS             complement(78756..80234)
                     /locus_tag="RPH49_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123265.1"
                     /translation="MNCTFRLLTSNKFDMMLCLPIHKCVNLFYTFVYHSNLLKIILQG
                     VIIIITYLESFKSLYHKAFYKFVLSVLSLPIFLYAVIKFFFSAKRKNFYANNSEISEI
                     EQALHQKYKYLSQQKLSTQIHKEALKIFKAQSSNTNSKNIEQAHFSTYFENVLFHKFI
                     IIKVILALPMFILLTIYLQPLVRYIFERIVMAVIVIIGVIVSVFTILYFSPLDAAYSI
                     LGQNATKAQIHQFNVLHHLNEPYFIQLWDTIKGVFTFDLGTTYKGNEVVTKAVGERIP
                     ITIIVAVLALIVALIIAIPIGIISAMKRNSWLDITLMIIALIGLSIPSFWQGLLFILA
                     FSLKLDILPPSYMPEHPISLILPVLVIGTSIAASITRMTRSSVLEVMRSDYVLTAYAK
                     GLSTTQVVIKHILKNAIIPIVTLVGLLVAELLGGSAVTEQVFNINGIGRYIVQKQLIP
                     DIPAVMGGVVYISIVISLANLIIDIFYALIDPKLRSEINERK"
     gene            80191..81783
                     /locus_tag="RPH49_000066"
     CDS             80191..81783
                     /locus_tag="RPH49_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123266.1"
                     /translation="MSNLLEVNSLNVQFNYDETTVQAVKNVSFELRKKHILGIVGESG
                     SGKSITAKSILGLLPDYPDHTLTGEIIFNGQSLTNLSTSALQQIRGKDISMIFQDPLS
                     SLNPRLTIGKQITEVLFQHKRVSKSEAKSMTIDILEKVGIKHATRQFDAYPHELSGGM
                     RQRVMIAMALILKPQILIADEPTTALDASTQNQLLQLMKSLYEYTETSIIFITHDLGA
                     VYQFCDDVIVMKDGSVVESGTVESIFKSPQHTYTKRLIDAIPDIHQTRPPRPLNNDIL
                     LKFDRVSVDYKLPSGSLYRAVNDINLAIRKGETLGIVGESGSGKSTLAKTVVGLKEVS
                     EGFIWYNELPLSLFKDDELKALRQEIQMIFQDPFASINPRFKVIDVIKRPLIIHGKVK
                     DNDDIIEIIVSLLEKVGLDQSFLYRYPHELSGGQRQRVSIARALAVESKVIVCDEAVS
                     ALDVSIQKDIIELLKQLQLDFGITYLFITHDMGVINEICDRVAVMKNGEIVELNNTED
                     IIKHPQSDYAKQLISEVAVIAK"
     gene            complement(82048..83160)
                     /locus_tag="RPH49_000067"
     CDS             complement(82048..83160)
                     /locus_tag="RPH49_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RES family NAD+ phosphorylase"
                     /protein_id="HDY5123267.1"
                     /translation="MKICEKCFNNTEIVEIIANDNSKIDNCDIDNNHLGVKIFDTTKD
                     KDKLELIRDYLRPALELYDISINLPDTFSPKEGKKIEIALKDDWSIFKVEEAQISCIL
                     NELFKDDENLDRRVLEDLVGAKIINDKKYTNENLIVANNDWDGFCESLKYNNRFHNNM
                     INLENLAFFLDITTNYYSIEEFRERFEPLYRSRIVKFITEKSELMSPPKGFATAGRLN
                     SKWISVLYLSTKEQVSIEEVKPKHNDIIYIGKVKLQKNVTKEKLKIANLTNLTSNAIK
                     AGDDGFRKYFVNYQTLKKIHKGITNPSDEQGIDYLPFQYLADYIRSLKYDGIMYESIL
                     QDGTFNFVFFDQSLFECVNYERKRVSDVKYTLTKLS"
     gene            complement(83147..84070)
                     /locus_tag="RPH49_000068"
     CDS             complement(83147..84070)
                     /locus_tag="RPH49_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDY5123268.1"
                     /translation="MYYPYLRGKQNELFAIKELLEKGLIGDCIQPIIEPIKYTTTFKN
                     TLQYCGEKAFSINLVVNSKLTEEEISNETVEHLTEIITKNKSVIQKAYLGPSDEGNDR
                     LKQQFSSNSLAILTSVDDWEMFGDKNKLEMVFIPDDRHIKRKLRNIPNKGIIMDPFNK
                     LSRNVDYLDNDDEFYSDDHLYYKEDGYVAFSDYSVIGGEYVDGGFSPLAIAIHIVYFD
                     EANELRVKHFVSDSNNDRSNPGKKFFEAVDKLVTWSKNLDIKNRSYALGQFEELNENN
                     KYPGLGLIKRLSIMHHLEIMNRYLESQNENM"
     gene            complement(84072..84914)
                     /locus_tag="RPH49_000069"
     CDS             complement(84072..84914)
                     /locus_tag="RPH49_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7726 family protein"
                     /protein_id="HDY5123269.1"
                     /translation="MDNRNMINRVFSQKILHQIAIKNKSDVVDEAYDFYIQGPKNINV
                     IQKMKSLYNYLKKSYRNEYFYKNTMLNKLLLGRHSVNTTTALSEMPIGKSIADFILLN
                     GKGVVYEIKTELDKLDRLDNQINDYYEVFNYVVVITNNKHLNKVMARYKDTTVGILVL
                     TTRNTLSEVQKPKENNSLLNTKAMYNFLRKEERKRVIAQNHMDVPTYNDFTEYDVLFD
                     VFKEIPMTKLHNNMISELKKRGNMKEYKDEFLAAPTEIKFLLYFAKMTKKDKNKLYHF
                     LKED"
     gene            complement(85114..87903)
                     /locus_tag="RPH49_000070"
     CDS             complement(85114..87903)
                     /locus_tag="RPH49_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDY5123270.1"
                     /translation="MAYQSEYALENEMMNQLEQLGYERVTIRDNKQLLDNFRTILNER
                     HADKLEGNPLTDKEFQRLLTMIDGKSIFESARILRDKLPLRRDDESEIYLSFLDTKSW
                     CKNKFQVTNQVSVEDTYKARYDVTILINGLPLVQVELKRRGIDINEAFNQVKRYRKQN
                     YTGLFRYIQMFIISNGVETRYFSNNDSELLKSHMFYWSDKQNNRINTLQSFAESFMRP
                     CQLAKMISRYMIINETDRILMAMRPYQVYAVEALIQQATETGNNGYIWHTTGSGKTLT
                     SFKASQILSQQDDIKKVIFLVDRKDLDSQTEEEFNKFAKGAVDKTFNTSQLVRQLNDK
                     SLPLIVTTIQKMAKAIQGNAHLLEQYKTNKVVFIIDECHRSQFGDMHRLVKQHFKNAQ
                     YFGFTGTPRFPENSSQDGRTTADIFGRCLHTYLIRDAIHDGNVLGFSVDYINTFKNKA
                     LKAEDNSMVEAIDTEEVWLADKRVELVTRHIINNHDKYTRNRQYSSIFTVQSIHALIK
                     YYETFKRLNKKLEQPLTVAGIFTFKPNEDDRDGEVPYHSREKLEIMISDYNKKFETNF
                     STDTTNEYFNHISKNVKKGVKDSKIDILIVVNMFLTGFDSKVLNTLYVDKNLMYHDLI
                     QAYSRTNRVEKESKPFGKIVNYRDLKKETDDALRVFSQTNDTDTILMRSYEEYKKEFM
                     DAYRELKMIVPTPHMVDDIQDEEELKRFVEAYRLLAKIILRLKAFDEFEFTIDEIGMD
                     EQENEDYKSKYLAVYDQVKRATAEKNKVSILNDIDFEIEMMRNDTINVNYIMNILRQI
                     DLEDKAEQRRNQEQIRRILDHADDPTLRLKRDLIREFIDNVVPSLNKDDDIDQEYVNF
                     ESIKKEAEFKGFAGERSIDEQALKTISNDYQYSGVVNPHHLKKMIGDLPLKEKRKARK
                     AIESFVAETTEKYGV"
     gene            complement(88082..88936)
                     /locus_tag="RPH49_000071"
     CDS             complement(88082..88936)
                     /locus_tag="RPH49_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123271.1"
                     /translation="MELNEMINFVKENNKIMVTLSLTIFTSVIFPELKSWYSKIINTE
                     NKYRIFDRAIIMIGTVLPMYFLLGFLNYKIYIKLLERPHSEFINTIWFSLIGISYGLI
                     LFIAISTYRNYLAIVNRFQLYKMCENCDYIHPYRFVVNKESTLIKDCFKVGNNDLYEP
                     GSNYKIINLNQTIYGHYEKVESFYQNKNDKIFHIITLNRKNLIRSWLFINNWSIILCR
                     FTMPIVFTLFIFSLSYFDNGIYNAFIPIVMYIFTFVFQSIIFNKIYTENKQLRTQYIQ
                     KLNSGIEV"
     gene            complement(89159..90034)
                     /locus_tag="RPH49_000072"
     CDS             complement(89159..90034)
                     /locus_tag="RPH49_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDY5123272.1"
                     /translation="MTNILYRIDKQLSDFTKTEKIIADYILKNPHKIIDMTVNDLADV
                     TNVSTASIVRFSRKMTHQGFQELKIAISRYLPEDIATNPHLELIENEPVETLKNKMIA
                     RATNTMRFVATNIMDAQIDAICDVLKNARTIFLFGFGASSLTIGDLFQKLSRIGLNVR
                     LLHETHLLVSTFATHDDRDCMIFVTNQGSHSELQSIAQVATHYSIPIITISSTANNPV
                     AQIADYALIYGRTDENEMRMAATTSLFAQLFTVDILYYRFVALNYHAILDCITQSKMA
                     LDNYRKHLATIDFKH"
     gene            complement(90037..91491)
                     /locus_tag="RPH49_000073"
     CDS             complement(90037..91491)
                     /locus_tag="RPH49_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDY5123273.1"
                     /translation="MTKEQQLAERIIAAVGGMDNIDSVMNCMTRVRIKVLDENKVDDQ
                     ELRHIDGVMGVIHDERIQVVVGPGTVNKVANHMAELSGVKLGDPIPHHHNDSEKMDYK
                     SYAADKAKANKEAHKAKQKNGKSNKVLKSIANIFIPLIPAFIGAGLIGGIAAVLSNLM
                     VAGYISGAWITQLITVFNVIKDGMLAYLAIFTGINAAKEFGATPGLGGVIGGTTLLTG
                     IAGKNILMNVFTGEPLQPGQGGIIGVIFAVWILSIVEKRLHKIVPNAIDIIVTPTIAL
                     LIVGLLTIFIFMPLAGFVSDSLVSVVNGIISIGGVFSGFIIGASFLPLVMLGLHHIFT
                     PIHIEMINQSGATYLLPIAAMAGAGQVGAALALWVRCKRNTTLRNTLKGALPVGFLGI
                     GEPLIYGVTLPLGRPFLTACIGGGIGGAVIGGIGHIGAKAIGPSGVSLLPLISDNMYL
                     GYIAGLLAAYAGGFVCTYLFGTTKAMRQTDLLGD"
     gene            complement(91503..92399)
                     /gene="murQ"
                     /locus_tag="RPH49_000074"
     CDS             complement(91503..92399)
                     /gene="murQ"
                     /locus_tag="RPH49_000074"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDY5123274.1"
                     /translation="MENSTTEARNEATMHLDEMTVEEALITMNKEDQQVPLAVRKAIP
                     QLTKVIKKTIAQYKKGGRLIYIGAGTSGRLGVLDAAECVPTFNTDPHEIIGIIAGGQH
                     AMTMAVEGAEDHKKLAEEDLKNIDLTSKDVVIGIAASGKTPYVIGGLTFANTIGATTV
                     SISCNEHAVISEIAQYPVEVKVGPEVLTGSTRLKSGTAQKLILNMISTITMVGVGKVY
                     DNLMIDVKATNQKLIDRSVRIIQEICAITYDEAMALYQVSEHDVKVATVMGMCGISKE
                     EATRRLLNNGDIVKRAIRDRQP"
     gene            complement(92399..93454)
                     /locus_tag="RPH49_000075"
     CDS             complement(92399..93454)
                     /locus_tag="RPH49_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDY5123275.1"
                     /translation="MTGFSVYLGQPLDEAYIKRMIKQGYQMIFTSVQIPEEDDETKYH
                     YFTKLLNLLKHEQVTYLIDANPSILTPSFYEHLRQYDAQFMIRIDHSTSIEAIEAIMA
                     QGLKCCLNASIISRELLTSLHQQLNDFTLLSFCHNYYPRPDTGLSVDLVNKKNELIYQ
                     FNPKAQIYGFIVGSGLRGPLHKGLPTIEATRHSHPVVAAKLLQETGVSEVLVGDSLIE
                     MRQAKQLIDFCKHRHFTLCIEEVFDTTVTYLFDMCHKVRPDNPENVIRSETSRQICPH
                     SIQPQFTTQRRIGSVTVDNLNNGRYQGEMQIVRQTLSAHDNVNVVAQIIKEDLPLLSC
                     IEPNDTFDFQKTRECKK"
     gene            94039..96084
                     /locus_tag="RPH49_000076"
     CDS             94039..96084
                     /locus_tag="RPH49_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIABC"
                     /protein_id="HDY5123276.1"
                     /translation="MRKKLFGQLQRIGKALMLPVAILPAAGLLLAIGTAMQGESLQHY
                     LPFIQNGGVQTVAKLMTGAGGIIFDNLPMIFALGVAIGLAGGDGVAAIAAFVGYIIMN
                     KTMGDFLQVTPKNIGDPASGYASILGIPTLQTGVFGGIIIGALAAWCYNKFYNINLPS
                     YLGFFAGKRFVPIMMATTSFILAFPMALIWPTIQTGLNAFSTGLLDSNTGVAVFLFGF
                     IKRLLIPFGLHHIFHAPFWFEFGSWKNAAGEIIHGDQRIFIEQIREGAHLTAGKFMQG
                     EFPVMMFGLPAAALAIYHTAKPENKKVVAGLMGSAALTSFLTGITEPLEFSFLFVAPL
                     LFFIHAVLDGLSFLTLYLLDLHLGYTFSGGFIDYFLLGILPNKTQWWLVIPVGLVYAV
                     IYYFVFRFLIVKLKYKTPGREDKQSQAATASATELPYAVLEAMGGKANIKHLDACITR
                     LRVEVNDKSKVDVPGLKDLGASGVLEVGNNMQAIFGPKSDQIKHEMQQIMNGQVVENP
                     TTMEDDKDETVVVAEDKSATSELSHIVHAPLTGEVTPLSEVPDQVFSEKMMGDGIAIK
                     PSQGEVRAPFNGKVQMIFPTKHAIGLVSDSGLELLIHIGLDTVKLNGEGFTLHVEEGQ
                     EVKQGDLLINFDLDYIRNHAKSDITPIIVTQGNITNLDFKQGEHGNISFGNQLFEAK"
     gene            complement(96063..96164)
                     /locus_tag="RPH49_000077"
     CDS             complement(96063..96164)
                     /locus_tag="RPH49_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123277.1"
                     /translation="MIPQNTIAKKKQARHLMKVYAPVYSKHYLASNN"
     gene            96357..97997
                     /locus_tag="RPH49_000078"
     CDS             96357..97997
                     /locus_tag="RPH49_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-keto acid decarboxylase family protein"
                     /protein_id="HDY5123278.1"
                     /translation="MKQRIGAYLIDAIHRAGVDKIFGVPGDFNLAFLDDIISNPNVDW
                     VGNTNELNASYAADGYARLNGLAALVTTFGVGELSAVNGIAGSYAERIPVIAITGAPT
                     RAVEQAGKYVHHSLGEGTFDDYRKMFAHITVAQGYITPENATTEIPRLINTAIAERRP
                     VHLHLPIDVAISEIEIPTPFEVTATKDTDASTYIELLATKLHQAKQPIIITGHEINSF
                     HLHQELEDFVNQTQIPVAQLSLGKGAFNEENPYYMGIYDGKIAEDKIRDYVDNSDLIL
                     NIGAKLTDSATAGFSYQFNIDDVVMLNHHNIKIDDFTNDEISLPSLLKQLSNISYTNN
                     ASFPAYHRPTSPDYTVGTEPLTQQTYFKMMQNFLKPNDVIIADQGTSFFGAYDLALYK
                     NNTFIGQPLWGSIGYTLPATLGSQLADKDRRNLLLIGDGSLQLTVQAISTMIRQHIKP
                     VLFVINNDGYTVERLIHGMYEPYNEIHMWDYKALPAVFGGKNVEIHDVESSKDLQDTF
                     NAINGHPDVMHFVEVKMSVEDAPKKLIDIAKAFSQQNK"
     gene            98064..98621
                     /locus_tag="RPH49_000079"
     CDS             98064..98621
                     /locus_tag="RPH49_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase family protein"
                     /protein_id="HDY5123279.1"
                     /translation="MINFNKTALVLIDLQEGILKMDYAPHTAENVVQNANKLIDVFRK
                     NNGFIAFVRVNFYDGKDVLQPNAMISLPPKEGDDYSRFHHLLDKRDDDFVIDKRHFSA
                     FVGTDLDLQLRRRGIDTIVLGGVATHIGVDTTARDAYQLNYNQFFVTDMMSAQNETLH
                     QFPIDNVFPLMGQTITTNDFLNILN"
     gene            98897..100252
                     /gene="brnQ"
                     /locus_tag="RPH49_000080"
     CDS             98897..100252
                     /gene="brnQ"
                     /locus_tag="RPH49_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDY5123280.1"
                     /translation="MKKKLTFKENMFIGSMLFGLFFGAGNLIFPIHLGQAAGSNVFIA
                     NLGFLITAIGLPFLGIIAIGISKTSGLFEIASRVNKTYAYIFTIALYLVIGPFFALPR
                     LATTSFEIAFSPFLSPKQITLYLFIFSFVFFVIAWFFARKPSRILEYIGKFLNPVFLV
                     LLAIILLFAFIHPLGGISDAPISKQYQSHALFNGFLDGYNTLDALASLAFGIIIVATI
                     KKLGIENPTDIAKETIKSGTISIIMMGIIYTLLAIMGTLSIGHFKLSENGGIALAQIT
                     QYYLGNYGIVLLSLIVMVACLKTAIGLITAFSETFEHLFPKMNYLAIATVVSFISFLF
                     ANVGLTKIIMYSVPVLMFLYPLAIALIVLTLFSSKFHHSKIIYQCTIFFTMIAALVDG
                     LKASPEFISSTSFSQTLINFSQKYLPLSDIGMGWVVLSLIGFIIGFIIFKIKHRKIPQ
                     A"
     gene            100505..101689
                     /gene="rocD"
                     /locus_tag="RPH49_000081"
     CDS             100505..101689
                     /gene="rocD"
                     /locus_tag="RPH49_000081"
                     /EC_number="2.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="HDY5123281.1"
                     /translation="MNSIIELTDYYSSNNYAPLKLVISKGKGVKVWDTDGKQYIDCIS
                     GFSVANQGHCHPTIVKAMTEQASKLSIISRVLYSDNLGKWEEKICHLAKKDKVLPLNS
                     GTEAVEAAIKIARKWGSEVKGITDGQVEIIAMNNNFHGRTLGSLSLSNHDAYKAGFHP
                     LLQGTTTVDFGDIEQLTQAISPNTAAIILEPIQGEGGVNIPPKGYIQAVRQLCDKHQI
                     LLIADEIQVGLGRTGKWFAMEWEQVVPDIYILGKALGGGLYPVSAVLANNDVMRVLTP
                     GTHGSTFGGNPLAIAISTAALDVLKDEQLVERSERLGSFLLKALLQLKHPSIKEIRGR
                     GLFIGIELNTDAAPFVDQLIQRGILCKDTHRTIIRLSPPLVIDREEINQIVAAFQDVF
                     KN"
     gene            101728..102759
                     /locus_tag="RPH49_000082"
     CDS             101728..102759
                     /locus_tag="RPH49_000082"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDY5123282.1"
                     /translation="MIKVGIVGGSGYGAIELIRLLQTHPHITIAHIYSHSKVDEPLKL
                     TFPHLQHIMQHFEALTVDNNDCDVIFFATPAPVSKTCIPPLVEKGIHVIDLSGAFRIK
                     NREIYEAYYKETAAAQDDLNHAIYSISEWQSFDNNGTKLISNPGCFPTATLLALHPLI
                     SEKIVDLSSIIIDAKTGVSGAGRSLSQRVHFSEMNENLSAYAIGNHKHKPEIEQYLSI
                     VAGQDVSVIFTPHLVPMTRGILSTIYVKLSSEYTTESLHKLMTSYYANQPFVRIRDIG
                     TFPTTKEVLGSNYCDIGIYVDETTQTAILVSVIDNLVKGASGQAIQNLNILYNFEVTT
                     GLKQSPVYP"
     gene            102771..104012
                     /gene="argJ"
                     /locus_tag="RPH49_000083"
     CDS             102771..104012
                     /gene="argJ"
                     /locus_tag="RPH49_000083"
                     /EC_number="2.3.1.1"
                     /EC_number="2.3.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate
                     N-acetyltransferase/amino-acid acetyltransferase ArgJ"
                     /protein_id="HDY5123283.1"
                     /translation="MKHQETTSQQYNFSIIKHGDISTPQGFTAGGMHIGLRANKKDFG
                     WIYSSSLASAAAVYTLNQFKAAPLIVTEDTLQKSKGKLQALVVNSANANSCTGQQGID
                     DARQTQTWVAQQLQIPSEHVAVASTGVIGEYLPMDKIKNGTDHIKDTKYTTPGAFNEA
                     ILTTDTCTKHIAVSLKIDGKTVTIGGSAKGSGMIHPNMATMLAFITTDAAIESNTLHQ
                     LLKSSTDHTFNMITVDGDTSTNDMVLVMANHQVEHQILNQDHPQWETFVDAFNFVCTF
                     LAKAIARDGEGATKLISVNVSGAKSISDARKIGKTIVSSNLVKSAIFGEDANFGRIIT
                     AIGYSGCEIDPNCTYVQLNQIPVVDKGMAVLFDEQAMSNTLTHEHVTIDVQLGLGNAT
                     ATAYGCDLSYDYVRINASYRT"
     gene            104028..104792
                     /gene="argB"
                     /locus_tag="RPH49_000084"
     CDS             104028..104792
                     /gene="argB"
                     /locus_tag="RPH49_000084"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDY5123284.1"
                     /translation="MKFIVIKIGGSTLSDMHPSIINNIKHLRSNNIYPIIVHGGGPFI
                     NDALSNQQIEPHFVNGLRVTDKATMTITKRTLIADVNTALVAQFNQHQCSAIGLCGVD
                     AQLFEITSFDQQYGYVGVPTALNKDALQYICDKFVPIINSIGFNNHDGEFYNINADTL
                     AYFIASSLKAPIYVLSNIAGVLINDVVIPHLPLGDINQYIEHGDIYGGMIPKVLDAKN
                     AIENGCPKVIIASGNKPNIIESIYNNDFVGTTILNS"
     gene            105060..105539
                     /locus_tag="RPH49_000085"
     CDS             105060..105539
                     /locus_tag="RPH49_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDY5123285.1"
                     /translation="MGIFIYAGIIGGLLSGIVKLGWEVMFPPRTPERNATNPPQELLQ
                     QLGFSSEFTHQTYTFSNMELPWVSFIVHFSFSIVIAIIYCILVKKYAYLAMGQGAVFG
                     IAIWVLFHLIIMPIMHTVPAVWDQPFQEHLSEFFGHIVWMMTIELVRQHFVYRYKLN"
     gene            complement(105867..106511)
                     /locus_tag="RPH49_000086"
     CDS             complement(105867..106511)
                     /locus_tag="RPH49_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDY5123286.1"
                     /translation="MTVFVMQLQSNLKSIEELISQSRWSYKKPRTVNYRYNQDKLMHR
                     LGDILVQYGIQHDTGLLPHEWHYHISPRGKADIVQHNRDGQPIYVSLSYSYPYIVCVV
                     DKEPVGIDIEKISQRLDWRTLVTCFSTNEAHQICSLNDFYQIWTQKESFTKLIGEGLI
                     KGLDIYDMTQSHFYQSREVKFKQFIFDQFMVQVCFLGQAPWGYKKVSVFQLLSS"
     gene            complement(106524..113699)
                     /locus_tag="RPH49_000087"
     CDS             complement(106524..113699)
                     /locus_tag="RPH49_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid adenylation domain-containing
                     protein"
                     /protein_id="HDY5123287.1"
                     /translation="MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMY
                     ALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPTSSANYDLEAFFKQELS
                     TYHFNDSPLFKFKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTR
                     QHAHLNRNDDKHNQDASHIALDSNYFRLENNSDIHIDSYLPIKHPFEQALYQTYLIDD
                     MTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQ
                     RFTTDFNKCVLQNMSQLQCANSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLA
                     DIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTE
                     RDIQLYDDINVSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDL
                     AHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKD
                     ATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNP
                     KGTLIPHRGIVRLVHQNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKK
                     EQLLNPIALEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVD
                     LLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGECRCG
                     VGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLY
                     RKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNK
                     IKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHL
                     LCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFE
                     LAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSG
                     LNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQRIVADVVADFEEVNTHFTDEQEIMR
                     QFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLL
                     PLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFT
                     MNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQM
                     LGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRN
                     PLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYIINIEYNTD
                     LYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGN
                     KSIISYFNEAVSRQGNHVALVMNDLTMTYETLHNYVDAIAHMLLSNGVGNGQRVALFT
                     ERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVI
                     QLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLL
                     NLVHAWSTELQLGNNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPAQLQ
                     QLINKHRVTVASIPLQMCSVMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPS
                     ESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAI
                     GYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELD
                     EIENAILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDHLPKYMIPKT
                     ITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVG
                     VDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALP
                     DNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGVTGFLGAYLIEALQGYSHRIYCF
                     IRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHA
                     GARTDHFGDDDEFEKVNVQGTVDAIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSE
                     ADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTN
                     RFSMVMNDLLQLDCIGVSLAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMP
                     VKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMN
                     HISEKWPTITNNWLHHWAQYIKTIFNK"
     gene            complement(114146..115396)
                     /locus_tag="RPH49_000088"
     CDS             complement(114146..115396)
                     /locus_tag="RPH49_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5123288.1"
                     /translation="MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGI
                     YLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGIFGSHQLWQIIGFC
                     VAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGY
                     SMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLV
                     LKDRNYMLLISGFSIIMMGEFSISSYIAIRLKNQFETISIGSYDITGAKMLAILLMIN
                     TVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGE
                     IIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGAFLTSLQMGLYMF
                     IVLTIGASMLVAGVFGGQKQVNTN"
     gene            complement(115782..116807)
                     /locus_tag="RPH49_000089"
     CDS             complement(115782..116807)
                     /locus_tag="RPH49_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent formate dehydrogenase"
                     /protein_id="HDY5123289.1"
                     /translation="MKIVALFPEAVEGQENQLLNTKKALGLKTFLEERGHEFIILADN
                     GEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNI
                     GVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIG
                     IFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSTSDAITIHAPLT
                     PETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAP
                     ADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIA
                     SKSYTAK"
     gene            complement(116980..117339)
                     /locus_tag="RPH49_000090"
     CDS             complement(116980..117339)
                     /locus_tag="RPH49_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2294 domain-containing protein"
                     /protein_id="HDY5123290.1"
                     /translation="MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAH
                     MTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDID
                     LNDDEVISIFVFDKSIE"
     gene            complement(117556..118587)
                     /locus_tag="RPH49_000091"
     CDS             complement(117556..118587)
                     /locus_tag="RPH49_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA/acyl-ACP dehydrogenase"
                     /protein_id="HDY5123291.1"
                     /translation="MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALR
                     KNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLS
                     NPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFIL
                     RANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQ
                     IPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTS
                     HLSELISLKKNIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHL
                     GKLEAELKG"
     gene            complement(118600..119361)
                     /locus_tag="RPH49_000092"
     CDS             complement(118600..119361)
                     /locus_tag="RPH49_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123292.1"
                     /translation="MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPVLVG
                     KSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLI
                     RPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLN
                     LTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLN
                     LEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE"
     gene            complement(119358..120332)
                     /locus_tag="RPH49_000093"
     CDS             complement(119358..120332)
                     /locus_tag="RPH49_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDY5123293.1"
                     /translation="MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPI
                     THSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQ
                     KGSNIKAVALGHHEGNVIMGQKGMHLNEFNNNGDDYHFGIPHRYSTHYLLLEELRKQL
                     KIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDA
                     YCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSA
                     AWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS"
     gene            complement(120346..121086)
                     /locus_tag="RPH49_000094"
     CDS             complement(120346..121086)
                     /locus_tag="RPH49_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123294.1"
                     /translation="MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLL
                     NIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDE
                     EINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRY
                     KLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRN
                     DSHLLKIRNEIMETFALNHHQVEPEYYL"
     gene            complement(121428..121940)
                     /locus_tag="RPH49_000095"
     CDS             complement(121428..121940)
                     /locus_tag="RPH49_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4242 domain-containing protein"
                     /protein_id="HDY5123295.1"
                     /translation="MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENL
                     THGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIP
                     EGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAV
                     DTPIDGIEKL"
     gene            122119..122322
                     /locus_tag="RPH49_000096"
     CDS             122119..122322
                     /locus_tag="RPH49_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123296.1"
                     /translation="MDKESVVASLARNKKIAVETMTGQRYIIERILHTNDEKHIHILK
                     PKDVVLDVDTIKDIDENHLDDAT"
     gene            complement(122384..123343)
                     /locus_tag="RPH49_000097"
     CDS             complement(122384..123343)
                     /locus_tag="RPH49_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDY5123297.1"
                     /translation="MNGKKANTINRYKYFHHVDHQKIQQSSKKTLWASLIITLLFTVI
                     EFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILAAF
                     LNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTVILVRSLKQED
                     NINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRN
                     AWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEG
                     DDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT"
     gene            complement(123990..125477)
                     /locus_tag="RPH49_000098"
     CDS             complement(123990..125477)
                     /locus_tag="RPH49_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDY5123298.1"
                     /translation="MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHI
                     TRAKDKDVDYAVEVAQEAFESWSLTSKSERAQMLRDICDKLMAQKDKIAMIETLNNGK
                     PIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNF
                     PMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESG
                     NAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVE
                     GIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTG
                     KDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEI
                     FGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQ
                     VPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY"
     gene            125903..126286
                     /locus_tag="RPH49_000099"
     CDS             125903..126286
                     /locus_tag="RPH49_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HDY5123299.1"
                     /translation="MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDR
                     FYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLII
                     MVIIQTAVLFTFVKTLPKSNHKIEE"
     gene            126293..126619
                     /gene="isdI"
                     /locus_tag="RPH49_000100"
     CDS             126293..126619
                     /gene="isdI"
                     /locus_tag="RPH49_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylobilin-forming heme oxygenase IsdI"
                     /protein_id="HDY5123300.1"
                     /translation="MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLN
                     TEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDI
                     GYHYQK"
     gene            complement(126684..127829)
                     /gene="cap8P"
                     /locus_tag="RPH49_000101"
     CDS             complement(126684..127829)
                     /gene="cap8P"
                     /locus_tag="RPH49_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8P"
                     /protein_id="HDY5123301.1"
                     /translation="MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDML
                     DSVLSIFDIQADHDLNIMQDQQTLADLTANTLAKLDSIINEEQPDMILVHGDTTTTFV
                     GSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFE
                     NKDKESIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIF
                     KAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSY
                     LVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIED
                     DEAYQRMSQANNPYGDGQASQRICEAIEYYFGLRSDKPDEFIPLRHK"
     gene            complement(127906..129168)
                     /gene="cap8O"
                     /locus_tag="RPH49_000102"
     CDS             complement(127906..129168)
                     /gene="cap8O"
                     /locus_tag="RPH49_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8O"
                     /protein_id="HDY5123302.1"
                     /translation="MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQI
                     SIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMHALD
                     SILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILE
                     ELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNISLA
                     NELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKL
                     IQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLN
                     QEPDIEVCAYDPHVALDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVI
                     FDTKNVVKSSFEDVSYYNYGNIFNFIDK"
     gene            complement(129222..130109)
                     /gene="capN"
                     /locus_tag="RPH49_000103"
     CDS             complement(129222..130109)
                     /gene="capN"
                     /locus_tag="RPH49_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide type 5/8 biosynthesis
                     epimerase CapN"
                     /protein_id="HDY5123303.1"
                     /translation="MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSF
                     KDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYG
                     KEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCP
                     GNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTS
                     SVMYEIRRQSHHKTVLINMPSMLNKYFNKLLVFRKLFGNLIYSNTLYENNNALEVIPG
                     KMSLVIADIMDETTTKDKA"
     gene            complement(130109..130666)
                     /gene="cap8M"
                     /locus_tag="RPH49_000104"
     CDS             complement(130109..130666)
                     /gene="cap8M"
                     /locus_tag="RPH49_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8M"
                     /protein_id="HDY5123304.1"
                     /translation="MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPT
                     INNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEM
                     SIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTH
                     QSMMLDMYIIYKTIKNIVTSEGVHH"
     gene            complement(130677..131882)
                     /gene="cap8L"
                     /locus_tag="RPH49_000105"
     CDS             complement(130677..131882)
                     /gene="cap8L"
                     /locus_tag="RPH49_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8L"
                     /protein_id="HDY5123305.1"
                     /translation="MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGW
                     PYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKY
                     DQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYI
                     NRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKA
                     YREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDH
                     RIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMD
                     KQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREIN
                     TMKYYNLLK"
     gene            complement(131883..133088)
                     /locus_tag="RPH49_000106"
     CDS             complement(131883..133088)
                     /locus_tag="RPH49_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HDY5123306.1"
                     /translation="MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSI
                     LTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVLILLISILIESIALIIVFL
                     YFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLLLYY
                     LTQNWIVCFITSELFATIYTLVKLRGLTIGAYQSEDNNVVKDYVMLLSTNSLNNLNLY
                     LDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSHISVNESDNIKKQYLKT
                     NLFAIAALCLVMIICYPITIIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLN
                     TKHASITLQANYMTFHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKS
                     KFINKKDVD"
     gene            complement(133081..134247)
                     /locus_tag="RPH49_000107"
     CDS             complement(133081..134247)
                     /locus_tag="RPH49_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDY5123307.1"
                     /translation="MKFFVLCAIISMNIFIVISTFTKEVLGFPIEPVYYSTMVGIALI
                     TTVFAIYKIIVTQEIPRGLILLIAICLLYLAFYYFSPDKEEKLAKNNILFFLTWAVPA
                     AISGIYIKYINKATVERFFKLVFFIFSVSFIFVILIPKLTGEIPSYINFGLMNYQNAS
                     YLSAFTAGLGIYFIMKGSVKHKWIYVLFTIIDIPIVFIPGGRGGAILLILYGLFAFIL
                     ITFKRGIPIAVKSIMYISALSISSVLIYFLFTKGSNTRTFSYLQGGTLNLEGTSGRGP
                     IYEKGIYFIQQSPLLGYGPFNYYKLIGNIPHNIIIELILSFGLLGFFIIMICILLLVY
                     KMIRNYDPNTIDLLVMFIAIYPITLLMFSSNYLVVSEFWFVLFYFITKGRRHHG"
     gene            complement(134261..135370)
                     /locus_tag="RPH49_000108"
     CDS             complement(134261..135370)
                     /locus_tag="RPH49_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDY5123308.1"
                     /translation="MRILNIVSSNIVQDPRVLKQIETIKGVTNDYKIVGMNNSQATNK
                     RLENLDCNYRLLGSKVDPKNILSKLIKRIRFATGVIREIKAYKPDVIHANDFDVLLMV
                     YLSNYKKANIVYDAHEIYAKNAFINKVPLISKFVESIEKHIVKHRVNAFVTVSHAAKE
                     YYQSKGYKKEANVITNAPILNDSREFKEIENFKSIVYQGQIVMDRGYEEFIIASSAFK
                     QNAPSFIIRGFGPHEEVIKELISYNPENIRLDKPVEVKELVDKLAESNVGVVLTKPVS
                     INFEYTVSNKIFECIHAGLPVILSPVKEHIYLNEKYKFGIVLKEVTPLEIEKAVRKLR
                     DNHDLFNHLRQNAIKASKILNWQIESERLVKLYKF"
     gene            complement(135375..136001)
                     /locus_tag="RPH49_000109"
     CDS             complement(135375..136001)
                     /locus_tag="RPH49_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic acetyltransferase"
                     /protein_id="HDY5123309.1"
                     /translation="MRIAIEKIIGLLKNQSSKESNVKIHRLAYITNSKFDGNNYIDRW
                     CKIRNSHIGEYSYIGFGSDFNNVEVGRYCSISSDVKIGLGKHPTHFFSSSPIFYSNNN
                     PFNIKQKFIDFNDQPSRTTIKNDVWIGANVIIMDGLTINTGAVIAAGSVVTKNVGAYE
                     VVGGVPAKVIKKRFDNKTIEKLLESKWWEKTPDKLKGFSVEYLNKKDT"
     gene            complement(136004..137128)
                     /gene="cap8G"
                     /locus_tag="RPH49_000110"
     CDS             complement(136004..137128)
                     /gene="cap8G"
                     /locus_tag="RPH49_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8G"
                     /protein_id="HDY5123310.1"
                     /translation="MEKLKLMTIVGTRPEIIRLSSTIKACDQYFNQILVHTGQNYDYT
                     LNQIFFDDLELRQPDHYLEAVGSNLGETMGNIIAKTYDVLLREQPDALLILGDTNSCL
                     AAVSAKRLKIPVFHMEAGNRCFDQNVPEEINRKIVDHVSDVNLPYTEHSRRYLLDEGF
                     NKANIFVTGSPMTEVIEAHRDKINHSDVLNKLGLEPQQYILVSAHREENIDNEKNFKS
                     LMNAINDIAKKYKMPVIYSTHPRSWKKIEESKFEFDPLVKQLKPFGFFDYNALQKDAF
                     VVLSDSGTLSEESSILKFPGVLIRTSTERPEVLDKGTVIVGGITYNNLIQSVELAREM
                     QNNNEPMIDAIDYKDTNVSTKVVKIIQSYKDIINRNTWRK"
     gene            complement(137132..138241)
                     /gene="cap8F"
                     /locus_tag="RPH49_000111"
     CDS             complement(137132..138241)
                     /gene="cap8F"
                     /locus_tag="RPH49_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8F"
                     /protein_id="HDY5123311.1"
                     /translation="MNIVITGAKGFVGKNLKADLTSTTDYHIFEVHRQTKEEELESAL
                     LKADFVVHLAGVNRPEHDKEFSLGNVSYLDHVLDILTRNKKKPAILLSSSIQATQDNP
                     YGESKLQGEQLLREYSEEYGNTVYIYRWPNLFGKWCKPNYNSVIATFCYKIARNEEIQ
                     VNDRNVELTLNYVDDIVAEIKRAIEGTPTIENGVPTVPNVFKVTLGEIVDLLYKFKQS
                     RLDRTLPKLDNLFEKDLYSTYLSYLPSTDFSYPLLMNVDDRGSFTEFIKTPDRGQVSV
                     NISKPGITKGNHWHHTKNEKFLVVSGKGVIRFRHVNDDEIIEYYVSGDKLEVVDIPVG
                     YTHNIENLGDTDMVTIMWVNEMFDPNQPDTYFLEV"
     gene            complement(138254..139282)
                     /gene="cap8E"
                     /locus_tag="RPH49_000112"
     CDS             complement(138254..139282)
                     /gene="cap8E"
                     /locus_tag="RPH49_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8E"
                     /protein_id="HDY5123312.1"
                     /translation="MFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIFSRDEKKQDD
                     IRKKYNNSKLKFYIGDVRDSQSVETAMRDVDYVFHAAALKQVPSCEFFPVEAVKTNII
                     GTENVLQSAIHQNVKKVICLSTDKAAYPINAMGISKAMMEKVFIAKSRNIRSEQTLIC
                     GTRYGNVMASRGSVIPLFIDKIKAGEPLTITDPDMTRFLMSLEDAVELVVHAFKHAET
                     GDIMVQKAPSSTVGDLATALLELFEADNAIEIIGTRHGEKKAETLLTREEYAQCEDMG
                     DYFRVPADSRDLNYSNYVETGNEKITQSYEYNSDNTHILTVEEIKEKLLTLEYVRNEL
                     NDYKASMR"
     gene            complement(139272..141095)
                     /gene="cap8D"
                     /locus_tag="RPH49_000113"
     CDS             complement(139272..141095)
                     /gene="cap8D"
                     /locus_tag="RPH49_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8D"
                     /protein_id="HDY5123313.1"
                     /translation="MAHLSVKLRLLILALIDSLIVTFSVFVSYYILEPYFKTYSVKLL
                     ILAAISLFISHHISAFIFNMYHRAWEYASVSELILIVKAVTTSIVITMVVVTIVTGNR
                     PFFRLYLITWMMHLILIGGSRLFWRIYRKYLGGKSFNKKPTLVVGAGQAGSMLIRQML
                     KSDEMKLEPVLAVDDDEHKRNITITEGVKVQGEIADIPELVRKYKIKKIIIAIPTIGQ
                     ERLKEINNICHMDGVELLKMPNIEDVMSGELEVNQLKKVEVEDLLGRDPVELDMDMIS
                     NELTNKTILVTGAGGSIGSEICRQVCNFYPERIILLGHGENSIYLINRELRNRFGKNV
                     DIVPIIADVQNRARMFEILEMYKPYAVYHAAAHKHVPLMEDNPEEAVRNNILGTKNTA
                     EAAKNAEVKKFVMISTDKAVNPPNVMGASKRIAEMIIQSLNDETHQTNFVAVRFGNVL
                     GSRGSVIPLFKSQIEEGGPVTVTHPEMTRYFMTIPEASRLVLQAGALAEGGEVFVLDM
                     GEPVKIVDLARNLIKLSGKKEDDIRITYTGIRSGEKMFEELMNKDEVHPEQVFEKIYR
                     GKVQHMKCNEVEAIIQDIVNDFSKEKIINYANGKKGDNYVR"
     gene            complement(141115..141879)
                     /gene="cap8C"
                     /locus_tag="RPH49_000114"
     CDS             complement(141115..141879)
                     /gene="cap8C"
                     /locus_tag="RPH49_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8C"
                     /protein_id="HDY5123314.1"
                     /translation="MIDIHNHILPNIDDGPTNETEMLDLLKQATTQGVTEIIVTSHHL
                     HPRYTTPIEKVKSCLNHIESLEEVQALNLKFYYGQEIRITDQILNDIDRKVITGINDS
                     RYLLIEFPSNEVPHYTDQLFFELQSKGFVPIIAHPERNKAISQNLDILYDLINKGALS
                     QVTTASLAGISGKKIRKLAIQMIENNLTHFIGSDAHNTEIRPFLMKDLFNDKKLRDYY
                     EDMNGFISNAKLVVDDKKIPKRMPQQDYKQKRWFGL"
     gene            complement(141882..142568)
                     /gene="cap8B"
                     /locus_tag="RPH49_000115"
     CDS             complement(141882..142568)
                     /gene="cap8B"
                     /locus_tag="RPH49_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 8 capsular polysaccharide synthesis protein
                     Cap8B"
                     /protein_id="HDY5123315.1"
                     /translation="MSKKENTTTTLFVYEKPKSTISEKFRGIRSNIMFSKANGEVKRL
                     LVTSEKPGAGKSTVVSNVAITYAQAGYKTLIIDGDMRKPTQNYIFNEQNNNGLSNLII
                     GRTTMSEAITTTEIDNLDLLTAGPVPPNPTELIGSERFKELVDLFNKRYNIIIVDTPP
                     VNTVTDAQLYARAIKDSLLVIDSEKNDKNEVKKAKILMEKAGSNILGVILNKAKVDKS
                     SSYYHYYGDE"
     gene            complement(142584..143252)
                     /gene="capA"
                     /locus_tag="RPH49_000116"
     CDS             complement(142584..143252)
                     /gene="capA"
                     /locus_tag="RPH49_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide type 5/8 biosynthesis
                     protein CapA"
                     /protein_id="HDY5123316.1"
                     /translation="MESTLELTKIKEVLQKNLKILIILPLLFLIISAIVTFFVLSPKY
                     QANTQILVNQTKGDNPQFMAQEVQSNIQLVNTYKEIVKSPRILDEVSKDLNDKYSPSK
                     LSSMLTITNQENTQLINIQVKSGHKEDSEKIANSFAKVTSKQIPKIMSVDNVSILSKA
                     DGTAVKVAPKTVVNLIGAFFLGLVVALIYIFFKVIFDKRIKDEEDVEKELGLPVLGSI
                     QKFN"
BASE COUNT        45835 a        26880 c        21838 g        48897 t
ORIGIN      
        1 tgcgttgggg gcccgccaat acaacacttt agatcctact atattaattt atgtctcggg
       61 ctctaactct aaaatactta taatatacct ttataattta tctccatttg atgctatcac
      121 ttgtttatac caatagaacg aatctttttt caagcgttcc atcgtgccat gaccatcatt
      181 atctcgatca acatatatta aaccatagcg tttcttcatt tcaccagttg taaatgaaac
      241 aatatcaatg attccccacg gcgtataacc gattaaatct acaccatctt gatcaactgc
      301 ttctatcgct gctgtaatat gtacttttaa atattcaatg cgataatcat catgaatatg
      361 tccatctacc acttcatcaa ctgcaccaaa accattttcc acaataaaaa gtggcaactg
      421 ataacgatca tataacacat tcaatgtata tcttaagcca tctggatcaa tcgcccaacc
      481 ccaatcactc gttgcgatat gcggattctc cacagaatga ttcaaaccac cgttgacgat
      541 gttgttttca actgtagtat caacatcatg ttttacagcc gtagacatgt aataactaaa
      601 gccaatataa tcaaccgtgc cctgctgtaa aatactgtcg tccccttctt gccatccaaa
      661 atcatatcct tttcgtgcca acattttttt agcatagctt ggataataac ctcttacttg
      721 aacatccggg aaaaagaaac gtaagcgatt cgcaatttgt gcttccatca tatctttcgg
      781 atgacacgaa tatggataaa tgggtacatg tgaaatcatt gttccaatct taaatttcgg
      841 attaatctct ttaccaagac gaaccgctaa agcactggct aaaagttcat gatgtgctac
      901 ttgatacaag acttcttcgg gattatcatt ttctgttaat gctaccccag aatttgtcca
      961 taaaaagata ggatttgatg tgtccatctg attattaatt tcattaaacg tcatccaata
     1021 tgtcacttta tctttatatc tttcaaatac aacacgcgca aaatgcacaa aataatcgac
     1081 aacttctcta tttctaaatc caccataatg tttcgctaaa tgaagtggca tctcaaaatg
     1141 tgataacgtc acaacaggtt caataccttg tgcaattaat tcatcaaaga tacgatcata
     1201 aaaggcaagt ccttcttcat ttggcacatc ttcatcccca ttcggaaaga tacgtgtcca
     1261 cgcaatcgac gtacgtaaac atttcaatcc catttcttta aacaaggcaa tatcttcctt
     1321 ataacgatga taaaaatcaa taccttcatg atttggataa tagtgatttg gatctataga
     1381 ttctgtaatc tgacgtgctt tgccatgtgc accactcgtc ataacatcaa ttacacttaa
     1441 tcctttgcca cctttatcat atccaccttc aaattgattt gcggcaagag cgccacccca
     1501 cataaaattt tgcggtaatt ttgtcattat tacaacacac tcctagtttt taaatatttt
     1561 aaaaataaca tcttcagtcg taatgatttc attcattgtc agttctactt ttcctaaatc
     1621 ggcagagttg ctaataacga caataacgtc tgagttataa ccttgttcct gaatatattg
     1681 ttgatcgaat tgtaacagtg tttgcccagc ttcaacacga tcattttgct ttacaaagca
     1741 cttgaatcct ttaccttcca agtcaactgt attcacgcca atatgaatga ctatgtccac
     1801 accttcttct gaacgaatac cgatagcatg tttagtaggt acaatcatag atattaaacc
     1861 attgaacggt gcgattactt tggattcttc atgagctttg attgccaagc cttcacctac
     1921 cattttctct ctaaaaattg aatctcttac ttctttaagt aaaatacgac gaccagcgat
     1981 tggtgctttc actaaaatcg gtgttgtcac ttttgcttga ggtgtataac ttgtatcttg
     2041 gctattaata ttgtcagtat tcgcaccctc ttcaacatta gcatccttaa ttaatcgctg
     2101 taattgctga tacacttcat cgacatttcc gtttaatttt atgactaact gcgcatcatt
     2161 ttctgctaca gatgtcacat caactatttg tttcacttca tttgctgtag aaggaattgt
     2221 atgttgcata tgaattgtaa tgcccttcgt gtcatacgtt acatcaacaa tgttttcgac
     2281 accacccaca gctgtaagaa tgtcttgggc ttggtcttta tatttattac tcataaatat
     2341 taccccctca acttgatagt agaatgaaaa tgtatttact tacctccaat tataattgta
     2401 ccggttcatt ttgtaaatga cgatacaatt ataatatttt gtgctataat aattacagac
     2461 aaagtgaaat gaggataaaa tattgttaaa gtacgaacat attgctaagc aacttaatgc
     2521 gtttatacat cattctaatt tcaaacctgg tgataagttg ccaagtgtaa cgcaattaaa
     2581 agaacgttat caagtaagta agagtactat cattaaagca ttaggcttat tggaacaaga
     2641 tggtttgatc tatcaggcac aaggtagcgg tatatatgtg agaaatattg cagatgcaaa
     2701 tcgtatcaat gtttttaaga ccaatggttt ttctaaaagt ttaggcgaac atcgaatgac
     2761 aagtaaggtg cttgttttta aggagattgc aacgccacct aaatctgtac aagatgaact
     2821 ccaattaaat gcagatgata ccgtctacta tttagagcga ttaagattcg tggacgatga
     2881 tgttttatgt atcgaatatt cttattatca taaagaaatc gtgaaatatt taaatgatga
     2941 tattgctaag ggctctatct tcgactattt agaatcaaac atgaaacttc gtattggttt
     3001 ttcagatatt ttctttaatg tagatcaact caattcaagt gaagcggcat tactacaatt
     3061 atctaagggc gaaccatgtt tacgttatca ccaaacgttt tatacaatga ctggcaaacc
     3121 ttttgattcg tctgacatcg tatttcatta tcgtcatgca cagttttata ttcctagtaa
     3181 aaagtaatac atacatcaaa acgtctatat tccagttata aaccggagta tagacgtttt
     3241 ataagacata atttctttaa aaacagtgag aagtacattt ttaatcagaa aattacttta
     3301 tactgttctt tatgtttaca tgatctaaga acttatagtt tgaatcctat tgtataatat
     3361 ctcttcccct caaacgttaa aacacactaa aatcactcgg taatatgatg atctatactc
     3421 tgtattttgg ttttaagtgt ctgtatcccc ttataaaaat aactactaat ataatgacac
     3481 ctactgtgaa tataatgtcc caaggcattc tcccccacat gattgctttt acaagtggtt
     3541 gttcataaaa tgacgttagt cttgaatgcc aataaccatg ttctaatgca tctttaagtt
     3601 ggatataacc tactggcatt aatgtaacga acaccatacc tgccaagcca atatttaaag
     3661 cccaacatga tattttaatc catttttcaa ctttcggtgt ccaaaattct tttttagtaa
     3721 tatttttaaa aacatacaac gcaattgcaa ttgagaacat accatacacg ccagccatag
     3781 aaccatgggc atgtgctgca gtccattgcg taccatgttc aaagtagtta actgctggtg
     3841 tgttaattaa aaagcctaat gctccagcac caattgcatt ccacaatcct gttgaagcaa
     3901 gaaaaataaa tgtacctttg taaggaaaag cgatgtcact attcttatat aagcgatagt
     3961 gtgtgtatgc ttcccaaatt aataaacaaa gcggcacgac ttctaatgct gaaaaacaag
     4021 aacccagtgc tagccatatg gaatgatcac cttgccaata gtaatgatga cccataccaa
     4081 caatacctgt acctagtaat aagattaatt gaaaatataa tgcacgaatc gtcgtttcaa
     4141 tggtagttaa tttcatatta accattaaga aaccaatcaa cactacggca aatgcttcaa
     4201 atataccttc aacccataag tgaacaatcc accatcgcca gtaatcggca aacgtcacat
     4261 gtgaattcgg cattataaat aatgatgcaa gataaaataa cggaattgca attgctccaa
     4321 caaacaatag cgtcaataag tgacgtttat catgattcac ttgtactttg ttgcgaatag
     4381 ctggtaaaaa acctcgacaa agaatgataa cccataagac catacctact ataaataata
     4441 tttgccaaaa tttacctaat tctatatatt cccaaccaaa gtgcccgaat agccaccaat
     4501 gagaatcaat ccaacctaaa atatgacccc attctccaat catgctgccc atcacaacta
     4561 tgattaaggc ccaaaacaag atatctacta atacgccttg tttctttggt tctttgccca
     4621 atactttagg tacaatgtat attcctgctg ctaaccaagt cgtagcaacc cagaaaataa
     4681 ctaattgcac atgccatgtc ttcgcaatat taaatggaaa gagcctttgt atttctatac
     4741 caaaaaattt attctctaca taataatgtg ccagtaattc gcctaataat atttgaacca
     4801 aaaatagtaa catgacaacg actaaatatt tcccaacttt tcgttgacta tcagtgattt
     4861 tacgatccac ttcaatcttt ggtagttccc gttccgactc atacgtcggc ttcatgtcaa
     4921 attgataacg cttttgaata tatataatga atgccaagcc tgcaatcagt aatgttacag
     4981 atatagcagt ccataaaatc cctgcactag gcaacgtatt tcctgcatcc acatcgtatg
     5041 gccaattatt tgtatatgaa aatgtttttc caggtctatc tgttgacgat agccaagcac
     5101 cccagaaaaa gaattgactt aaatgttcaa ctttatttcc tgcgaccata taatcatcat
     5161 tttgaaactg tttaatcata ttttcattta accctacttg tttagggtta ttaacaaact
     5221 cttttttata ataatcttgc aaatatttta gaccgtatac ttgtcctggc gttaatacaa
     5281 gttgatcttc tttttcagaa taacgattaa tccgtatttc tttcatcact ttatctttaa
     5341 ctacggctaa ctctgcatga tttaatttat gaagttgctt atgataaata tcttgtgcat
     5401 aatatttacg catgccaatc aggtaatgat gtaatgcctc tgctgtataa tctggaccta
     5461 aataggaacc attgcctagg taggagccat aatctgttaa cccatatttc tcatatatcg
     5521 cttgcccact gatcagctcg ccttttgtaa caagcgtatg accttgttga tctactatct
     5581 ttgttggacg aggtgcttca tttttaaaaa tataccaacc acctactagt aaaattgaaa
     5641 acacaatcac taaaatcgtt agtagcactt taactaaacg tttatatgaa ctttgcatac
     5701 tcatttataa aatctcctct taattgcatt cttacatata agcatacgcc gtttttttat
     5761 aaagtgttga tgacattaag taatttcaag aatttgtcga aaaatattta attgaaattt
     5821 cacaaatgat ataacttaca ttttaattct tgtttaaatt aattcgttct accatttttc
     5881 aaaagtggca atacataaaa cgaacgccta aataccataa ttcctagtaa aaagtaatac
     5941 atacataaaa acgtctatat cccagttata aaccggagta tagacgtttt tttacgataa
     6001 taacaatggc tcaaattgct attatcttgc ttaggttttt cgttttagaa gaatattgct
     6061 acaaagacag gcacaactgc tacaacaact acaccaacta acactaaagc tatacttgcc
     6121 attgattctt ctacaggtcc taattctttg gctggtgcta cacctaatgt gtgaccactt
     6181 gttccaagtg ctaatcctcg ggcaataggg ttagtaattc ggaaaagctt caagaattta
     6241 ttacctaggg cataaataat gacaccattt aaaataactg ctaatgatgt taattctttt
     6301 ataccaccga taccagctga tactggtaac gcaatcgctg tagttgctgc ttgaggtaac
     6361 attgataaaa taacatcatt ggcaaattgt gctaacttcg caaaagttaa aataattaat
     6421 aacgctacaa ctgtaccgat accaatacct ccgatgatac gatgccaatg tttaacaagc
     6481 acttcacgct ttttatataa cggaatcgca aaacagattg ttgccggttc taagaagaag
     6541 taaataatat ctccacctat tttgtaagtc ttatacggaa tgcctgttaa atagaggaag
     6601 gccacaccaa ataccatact gacaaatagc ggtgcgaata agaagaaacg attagttttt
     6661 tcaaataata tggtcgctaa gaaaaatggt ataacggata acagtattcc gaagtaaggt
     6721 gtgtttagtg ctaagtggtt aatcatgagc ttgtgcctcc tctattttga tcttttttgt
     6781 gactttgtca cctttagatc tcgaagtaac tttcataata atttgtgtga catagccagt
     6841 acaaataagt aatagtattg ttgagacgat tattagtcca atgattaaaa atggtgcttg
     6901 gctaatgaca cctaaagagt taacaactga gataccggct ggtacgaaga gtaagccaat
     6961 gttatttgtt agtgtcgttc ctactttttc gacttcgcct aacttaacag caccagtaca
     7021 taataataca aataataata ctaaaccgat tactgatgca ggcataggaa ttggcataaa
     7081 tgattcaatt attttcgata caaagagtac taaagcaatt acaatgactt ggtgaaaaaa
     7141 gtgtgctggt tttgatgcgt ctttttgttg tttcacgacc attgcctcct acgtttgatt
     7201 taactaaagt atagatggct cacttcgatt tgcgtgattt ttagtccgaa atacaaaata
     7261 tcataggtaa aatgcataaa aaaaaggatt actgttaaag taatcctatc gacgctttaa
     7321 aatctttcat aaatgaacgt ccaacttgca tcttgacacc atttgtcaat attaccatat
     7381 aagtgtagtt aaaccattgt tgcacttctt taatgtgttt cgtgttaata atatatgaac
     7441 gatgaatacg tatgaaataa gcgggattca atcgtttttc ataacgattc aatggctctg
     7501 ttgtttcgta tttatgattt gttgtatgta tggttgtaat accattatgt gtgccaatcc
     7561 caataatatt ttgttgcttt aacatgtgaa ttttatcgtc aatttcaaca ggtaaacttt
     7621 gatcaaaatt cgccgacata tcattcgcaa ttgcacttgc gctattatca tctttggctt
     7681 tagtcgcacg aactttattg actgcttgtt caatacgttt ttgaccaaac ggtttcaaaa
     7741 tataatctgt cgcatttaat tcaaatgcct gtactgcgta ttggtcatgt gcagttgcaa
     7801 aaataatcgc aggtggctct ttcatctttt gaattttagc tcctaattcg ataccatttt
     7861 catccattaa attgacatct aaaaatataa tgtcatattg atttatcagt agtgcttcca
     7921 atgtttcttt tacattttct gcctcattaa tttcttcaaa accaccaatt tcatttaata
     7981 aatatgttaa ttcattacgt gctaatggct catcatctat gattaatgct ttcatattta
     8041 ttcctcctct tgtctttcat aaggaagtac acaccaaaaa gtggtaccgc tcgatgtcga
     8101 ttcaaattgt aatgctgcgg attttccaaa taatcctttt aggcgtaagt ttaaattttc
     8161 taaagcacta ccagttccag actctgattc tacagatgtt tctcccaaca aatgcatttt
     8221 atctttagaa ataccctgac cattatcttg tacaataata cgtacatgtg ttgcagtttc
     8281 tttaatcact gacacgtcaa tatcgttacc ttgctttcga ttcgtaaacg catgtttgat
     8341 ggcattttca actaaaattt gaattaaaaa tggtggtaca agcacatcgc gatacttgtc
     8401 ttcaacatta atattgatat taaatcttcc tggataacgt gcttgttcga gtgataagta
     8461 tgcacgcact tgacttaact ctttatctaa agtaatcgta tgttgctttg agccttgtaa
     8521 attcgctctg aaaaaataac tcaattctaa tagtaactct cgtgcctttt cgctatttat
     8581 tctaactaaa gctgaaatcg tgttaattga attgaagaaa aaatgcggac tcacttgtgc
     8641 ctgcaatgac ttaatttcag catctttcaa taacttactt tgcgtttcgg cttcaccaag
     8701 ttcaatttgg ctactaaaaa tatttgccaa tccttctgca agttgacgtt ccacaaaagt
     8761 taaatcatta gggtttgtaa aatacatctt caatgtaccg acgatagaac catgcatctc
     8821 aagtggtatc acgatagctg ctctaagcgg gcaattcgga tgactacaac caatctcttc
     8881 tttagtatga acttctttca actttcctga tttcaataca tctttagaca gacttgttaa
     8941 tatttcattt gttggtatgt gatgatcact acctgcacct acatgcgata agatttcatt
     9001 tttgcttgta attgctacgg cagatacttt cattaaattt ttaataatca tcgcaatttg
     9061 ctgtgccgat tctctattca atccttcttt aaaatacggc aatgtctggt tcatcaattg
     9121 cagtacatca tgtgtttgaa cagccttcat ttgctcctct tgctttaatg ttgaaatgat
     9181 aatagacata aaaatcgccg taccaacgct attaacaata atcattggta gtgcaattaa
     9241 tgatatgagg tcaaccgcat atgctttgtc gtgggaaaat gttaaaatgc tcaacatttg
     9301 aatcatttcc ataacaattc caatcatggc acttttcgca atactcgggt aacgcttgcg
     9361 tctttgagct tgtaaaccaa aataaccagc aattataccg ataaatatag atgagataag
     9421 ataaacttgt gcatccgccc cacccatata cactctgaaa atacctgaaa taacgccaac
     9481 aaatagacct acaaaagggc caccaactaa tcctgcgaca cctattgtca atacacgtgt
     9541 gttagctaaa gatacatcat catctaaacg gaagtacaca cttcctgaca aactatgttg
     9601 atgatcgatg acgataccag ttaaattaga cattaaggca aacaaactga aaataataca
     9661 taattgccaa cgtgctttcc atgtacgtcg acgattcatt aagtttttaa aatatggaat
     9721 attcatcaac acataggcca aaataataat taaacctaca cgctcaagta ataacattgt
     9781 tagcgatagc acgatagcac ctcagtgaat tataattatg tttattttat cataatagtg
     9841 catgtaaaat tcatgaataa attattaaaa aaacacgata ctatttaatt acctatacca
     9901 ttaaaatttc atatcaattc ttatgctaag ttgacaattt tccttttcaa aataatgact
     9961 atcatgtcac taaatttctg ttaagtatag cgaaaaactg ctgacattac tttgccaaca
    10021 gtttctaatc gcgttattta tgatactttt ttaaataaaa catgattctc taaatgaaca
    10081 tgctcatgtg ttaacacttc aagtgctttt aatctctgat aaacgagtcg ccaagtacca
    10141 catgcctcta tcggtggttc atagcttgat gttaaatcgc tcattttcac taacaattgt
    10201 cccgttgcaa tgtgatcaga tactaaatca tcaatcactg tattaatatc gtctactact
    10261 tcaccttgtt catatttaat gagttttgga aaatcaacat catcttcttt ttgcatatgc
    10321 tctaacatgc catttttaaa tgtatcgtat gttgctttta actcaactaa atatggatga
    10381 ttaggtccat gtactttcga taactttgtc acataaggtg ttaaattttt aaattcttct
    10441 cttagaggtt catgatatgc tgcttgaata tattgaataa gtgatgaaac atttaaaaat
    10501 ttaggattta acgaacctgg tgtattcgtt tgttcaactt cattgagacg ttgtaataat
    10561 tcgttcaaat ctacattttt cttttctaag actgctgctt ctatacttac ttgtccgcca
    10621 caacaaaaat ctattcccac acttctaaaa atatctgctg ctttcggata atcagttact
    10681 acatctgcta ctatgtcatt tttatttatc attatagata acctcctcat tttcagtgta
    10741 tacaatttaa tgtatttgaa aatgataaac gaggaaatgt cataatcatg tcataaacag
    10801 caaaataaaa ccctcaaatc atgttagttc acatagattt gagggcattt attatttatt
    10861 ttagcgagta agtcatatgt gcagtgttta acttaacaat atttttgaag tctcgcttct
    10921 taatatcttt actaagtaag atttccactt cgttttctga cgtttggctt aacattccca
    10981 tcaccatgtc gtcttttagc acgacactag ccataccttc ttcaaataca taaccacgat
    11041 ccagaccggt taaaatgatt ttgtttttac cttttaactt cattgagatt gaatccgtta
    11101 atgtaatagc tgtaaagtat aacgaaatgt tattaaagtc ttttgtgaaa tacggtgtta
    11161 atctataaaa atcattattc aaatgaatta atgcacttgt ttctgcagta tatgcatatt
    11221 tattacgttg attaccaaca cgcacttcaa atacttccgt acctatttgg acttctaaga
    11281 aaacatccca aattttttct ttaggtaaat ccgctttaat atcttctaac ataatgttaa
    11341 aacgatattg tttattcgca ttgacagtta aaggtacata cattgtgtgc ttcttgtttc
    11401 gtgaatgtaa tttaagtctg acatcataat gtccttcgcc aatcataaat tcatttaacg
    11461 ttagctctgt aacaatttta tgattatcaa atttaaatgc tgtcattttc acttttggct
    11521 tagcgatatc aatgccttca aagtatggtt cgccttcatt gaattgaatg tttaatttac
    11581 catctacaat atcaaaacgg tagtattgac cttgacggta actttcttct acagttctat
    11641 agttgtctat atccttcgct ctcgcgtagt gcaacaatgg tcgtaattta ctcatcacca
    11701 atgcatctac acgttctgga actgcttgta taaagtctcc tagagcatta atccattgcg
    11761 gttgatcttc tagtttaact ttaagtgaga agccattcgt acgagaaaaa ctaaaatgac
    11821 gatttaaaaa ttctgctaag atttgatctt tatgagcttc ttctaaatct gcatttaata
    11881 tttctacagc aatcaatctc atgacttcgt aaaagtcttc aggtgaaaca tacgcactac
    11941 tcatatgttc cccttcacgc tttgtagcat aataatacgc tttatcactt aacacactga
    12001 ttcgatttgc attcaaatat gctttcattg taaataattg atcttctgca ctctttaatt
    12061 cttctggaaa ataaatgtca ttatctttta gtaatgctgt tctatagatt ttagtcgggc
    12121 ttaaagtata gataattctt gaatttaaca atgtaacttc aggtgctgtt tctttaaaca
    12181 tagattgtgg tacaccacga ccattaacac ctttcatttt aatcaataag acatctgagt
    12241 gatgttcatc aataaatgct gctgcatcct ttaaagtctc tttgtttata tagtcatcgg
    12301 agtccacaaa taatacaaat tcaccttctg cttgttttaa cgccacattt ctaggtttac
    12361 ctggaccacc agaatttgtt tcgagttgac ttactttcaa gttcaattta ttgcgatact
    12421 tttcaactat ttgtaacgtt tgatctgttg aacagtcatc aactacaacc acttcaaatt
    12481 cagttttcgg aaaatcttgt ttcgcaaggc tattaagtaa ttctgttata tacttttctg
    12541 aattgtatgt tggaactatt actgaaaatt tcatcattat acctctccca ctttgaatac
    12601 tatataaact tagctaccaa ataaatttct gactaaacgc tcacttgatc ggccatcttg
    12661 atatttaaaa tgtttatcta agaatggaat gactttttct ccttcataat cttcattgtc
    12721 caaggcgtcc attaatgcgt caaatgattg cacaatttta cctggaacaa atgattcata
    12781 tggttcataa aaatcacgcg tcgtaatata atcttctaaa tcaaatgcat agaaaatcat
    12841 tggcttttta aatactgcat attcatatat taaagatgaa tagtcactaa ttaataaatc
    12901 tgttatgaac agtatatcat taacttctct aaagtcagaa acgtcaacaa aatattgttt
    12961 atgtttgtct gcaatattaa gtctattttt cacaaatgga tgcattttaa ataatacaac
    13021 cgcgttattt ttttcgcaat atcttgctaa acgttcgaaa tcaattttga aaaatgggta
    13081 atgtgctgta ccatgaccac tacctctaaa tgttggtgcg aaaagaatga ctttcttacc
    13141 tttaataatt ggtaattcat cttccatctc ttgtttgatc tgtgtcgcat aagcttcatc
    13201 aaatagtaca tcagtacgtg gaacacctgt aggcactaca tttttctctt taataccaaa
    13261 tgcttcagcg tagaatggaa tatcggtttc agatgataca taagcttttg tatagctacg
    13321 atgatttaat gaatcaataa atggtccacc ctttttacca gtacgactaa agccaactgt
    13381 tttaaaggca ccaacggcat gccatacttg aataacttct tgagaacgtc taaaacgcac
    13441 tgtataaatc aatgggtgaa agtcatcaac aaagatgtag tctgccttcc caagtaaata
    13501 tggcaatcta aacttgtcga tgatgccacg tctatctgta atattcgctt taaaaacagt
    13561 gtgaatatca tactttttat ctaaattttg acgtaacatt tcgttataga tgtattcaaa
    13621 gtttccagac atcgttggtc tagagtctga tgtgaacaac accgtattcc cttttttcaa
    13681 gtggaaaaat ttcgtcgtat taaatatcgc tttaaaaata aattgtcttg tattaaatga
    13741 ttgtttgcgg aaatacttac gtaattcttt atatttacga acgatataaa tacttttaac
    13801 ttccggagtc gttacaacaa catcaaggac aaattcatta acatcgctag aaatttcagg
    13861 tgtaacagta taaaccgttt tcttcgaaat gccgcctttt ctaaattctt ttaggtaagt
    13921 ctgcaataag aaattgattt taccattttg tgtttctaat tcgttgtatt cttcttcttg
    13981 ttctggcttt agattttgat atgcatcatt aatcacatct gggtttaact gtgcaatata
    14041 atcaagttct tgctcattca ctaataagta cttatcttca ggtaagtaat aaccattatc
    14101 taagatagct acattgaaac gacaaacgaa ttgattccca tctattttga catcattcgc
    14161 cttcattgta cgtgtctcag ttaaatttct taatacaaaa ttactatctt ctaaatctag
    14221 gttttcacta tgtccttcaa cgaataactg aacacgttcc caatagattt tatctatata
    14281 tatcttactt ttaaccaacg ttaattcatc cttttctatt tacataatcc attttaatac
    14341 tgttttaccc caagatgtag acaggtctgc ttcaaaagct tctgtaagat cattaattgt
    14401 tgcaatttca aattcttggc cttttaacaa cgctaattta tctacaatat ctgggtattg
    14461 aatgtataag tctacaacat cttggaaatc ttttgaacca cttcgactac taccaatcaa
    14521 cgttagtcct ttttccaata ctagacgtgt attaacttct actgggaact cacttacacc
    14581 taacagtgca atgcttcctt ctggtgaaat gtaatcgatc atttgattta tggctgattg
    14641 actaccgcga ccacccacac actcaaatgc atgatcaaat gttaagcctt caggtatttt
    14701 attaataaag aagacatcat caacaaatga gaagtgactc aatttataat ctgttttacc
    14761 aaagacatat attttagact ctggatataa tttacgtaat aaaatggctg taatgtaacc
    14821 taagttacca tcaccccaaa taccaaatgt atttttattt gaaatagatt tcttttcaaa
    14881 acgacgaata gcatgcaaac ttactgttac aagctctgta tatgaaataa tacttaaatc
    14941 aatatcatca ggtagtggta cagctctatc atgatttagc aacacaaaat cttgcataaa
    15001 cccatcatgt ccacttgatc tgaagtagct cgattttaaa tagttttcag caatgacatc
    15061 gtctttttct gtcggcgtat tcggtaccat aactactttt gtacctttat taaacacacc
    15121 tttactgtca aatacgacct caccaacacc ttcatgaatt aaagacattg gcaatttctg
    15181 agataagaca ttctcatcac ggctaccagt ataatatctt tgatcggcag cacaaattga
    15241 catatataaa ggacgtacaa tgacatagtc actgtaaata tctacgttgt tatacgtaac
    15301 ttcaaattgt ctaggtgcaa ctaattgata tacttgatta atcatcggca ataccacctc
    15361 gaataatagc attcgctact tttaaatcgt aaggtgttgt tactttaatg ttatataact
    15421 caccttttac aagtcgaacc ggtttgtttg tttctacaat aatcttacaa gcatcagata
    15481 aaatactctt ttgctcatca ctcaactgtg catagctttc ttttaataaa tttatattaa
    15541 acgattgagg tgtttgacct tggtacattt cattacgcac tggaattgca tcaatcgttt
    15601 gattatcttt agatgtaaca atcgtatcta tagcatcaat cactgtgtct actgcaccgt
    15661 actctaaagc agcttgaata ttttctttaa taatacgatg cgttaaaaat ggtctaactg
    15721 catcatgtgt cacaataaca tcgtcatcgt taataccatt tgttgattca atatgtttaa
    15781 cgatattcat aattgtatcg ttacgatcgc taccaccttg aatgacttca attctttcat
    15841 cagaaatttt gaattttcta agtgtatctt tcgtatgcgt catccattgt tgtggcgtcg
    15901 cgataataat tttttcaaaa tcattaatta aaataaattt ttctaatgta tggattaaaa
    15961 tcggtttgtt gtctaaatct aaaaattgtt taggtaaagg tacgttaccc attcttgagc
    16021 ctatacctcc agctagaata ccagcgtatt tcataaaata cttcctccat tcaactatat
    16081 ctatatttaa ttatttaaat ttcgttgcat tttccaattg aaaactcatt ttaaaatcaa
    16141 aactctaaat gtctatgtat tacttaaaat tatacatatt ttgcttatat tttagcatat
    16201 tttgtttaaa cctatattac attatatcag acgttttcat acacaaataa taacatacaa
    16261 gcaaacattt cgtttattat ttatatcact taactaatta atttataatt ttttattgtt
    16321 tttaagttat cacttaaaaa tcgtttggca aattcgttgt gacgcctttc catcttctaa
    16381 tgaacagaat ttttgataaa ataccgttcg tgcttcaata tactcatttg cagtctcatc
    16441 gatttgtttt aatgcatcaa tgagtgctgt ttgattttca acaattggac ctggcaactc
    16501 ttttttataa tccatgtaaa aacctctaag ctcatcgcca tatttatcta agtcatacgc
    16561 atagaaaatt tgcggacgct ttaatacacc gaagtcgaac atgacagatg agtagtcggt
    16621 aactaacgca tcgctgatta agtataaatc cgaaatgtct tcataatctg aaacgtcttt
    16681 cacaaaatca tcatgttcat caatacgtgt cacaactaaa taatgcatgc gtaataaaat
    16741 aacataatca tcatccagcg cttgacgcaa agcttctata tcaaagttaa cattaaattg
    16801 atatgaacct tctcgaatcg cttcatcgtc acgccaagtt ggcgcgtaca taatcacttt
    16861 tttatctaat ggaatattta atcttgtctt aataccatta atatattcag tatcattgcg
    16921 tttatgtgat aatttatcat ttcttggata acctgtttcc aaaatcttat ctcgactaac
    16981 atgaaatgca tgttgaaata tcgatgtcga atatggatta ggtgacacta gataatccca
    17041 acgctggctt tcttttgtaa agccatcttg gtaattttga gtatttgttc ctagcatttt
    17101 aacgttacta atatccaaac caatcttttt caatggcgtg ccatgccatg tttgtaagta
    17161 cgtcgttcgc ggtgatttat ataaccaatc tggtgtacgt gtgttaatca tccacgcttt
    17221 cgctcttggc atcgctaaaa accatttcat tgaaaacttt ttaacatatg gtacattgtg
    17281 ctgttggaat atgtgttcat atcctttttt cacaccccat attaattggg catcactatg
    17341 ttcagttaag tattcatata atgctttggg gttgtcgctg tattgtttac catgaaagct
    17401 ttcaaaataa attagattct tgtttggcaa ttttgatagt aatttaaatg tcgtatatat
    17461 actatgttct atcaattttt taattgtagt tttaatcatg tcgtacctcc gacgtgtttt
    17521 tgtaattata ttaatatgta tgagcaagct cattgtaacc atgcttatta tagcatttca
    17581 tcataaaata catttaacca ttacacttgt cgttaattat catacgaaat acatgattaa
    17641 tgtaccactt taacataaca aaaaatcgtt atccattcat aacgtatgtg tttacacgtt
    17701 tatgaattag ataacgattg gattgattat tttattttac aaaatgacaa ttcagttgga
    17761 agggtgatta cttttgattg aatcgcctta tgcatgaaaa atcaaaaggt tattctcatt
    17821 gtatagtcct gcttctcatc atgacatgtt gctcacttca ttgtcagaac ccttcttgaa
    17881 aactatgcct tatgactcat ttgcatggca agtaatatat gccaacatta gcgtctaaac
    17941 aaatctttga ctaaacgttc acttgagcga ccatcttgat atttaaaatg tttatctaag
    18001 aatggcacaa ctttttcaac ctcataatct tcattgtcca aagcatccat taatgcatca
    18061 aaggactgta caattttacc tggaacaaat gattcatatg gttcatagaa atcacgcgtc
    18121 gtaatgtaat cttctaagtc aaatgcatag aaaatcatcg gctttttaaa tactgcatat
    18181 tcatatatta aagatgaata atcactaatc aacaagtctg taacaaagag aatatcgtta
    18241 acttcacgat gatctgacac atcgataaag tattgtctat gttcacgtga aatattaagt
    18301 ctattttttg cgaacggatg cattttgaat aacacaactg cattatgctt ctcgcagtat
    18361 cttgctaaac gttcaaaatc aattttaaaa aatggataat gtgccgtacc gtgaccatta
    18421 cctctaaatg tcggtgcgaa tagaataact ttcttacctt ttataattgg caattcatct
    18481 tccatctctt gtttaatttg tgttgcataa gcttcatcaa atagtacatc agtacgtggt
    18541 acacctgttg gtacaacatt ttcttctcta attccaaatg cttcagcata aaatggaata
    18601 tcggtttctg atgaaacata tgctttcgtg taactacgat ggtttaatga atcgataaac
    18661 ggaccacctt ttttacctgt acgactaaag ccaactgttt taaaagcacc aactgcatgc
    18721 cacacttgaa taatttcttg tgatggtcta aagcgaaccg tataaattaa tggatggaaa
    18781 tcatcgacaa aaatataatc ggccttacca agtaaatatg gcaatctaaa cttgtctctc
    18841 catttacgtc tatccgtaat attcgcctta aataccgttt taatatcata atcaaaatct
    18901 actttttggc gtagtaactc atcatataca tatttaaagt tacctgataa attcggacgt
    18961 gaatctgatg tgaataatat tgttttgctt cttttaatat gtagtaactt tgtaatatta
    19021 aaaatagctt taaataagaa acttctactt tcaaatgaag ctttatggcc ttgtttatga
    19081 agccagtgtg cgcttgtcgc aatgacccct gatttctctt gaggtaaggt gatttcaata
    19141 tcaaatacaa attcgttaac gtcacttgct atttctggag taatggtata aaccgtatgt
    19201 tgtgatacgc cacctttgcg gaaaacttta gcttcgttgg ctaacacata gtttgctttt
    19261 ccattttgtg tagtcagctc attgtattct tcaatttgct cttcatttaa tgccgcataa
    19321 gcttgatcaa taatatttgg attaagttgt ccaatatact ctaactggtc atgataaaca
    19381 aacaaatatt tatccattgg taaataatac ccatcgtcta atattgcgac gttgaatcta
    19441 catataaatg tattaccgtc tattttcatt tcatttgctt ctaatgtttt tgtttcggtt
    19501 aaattcctca gaacaaattg tcctgatgtt aaatctacac cttcactatg tccttcaata
    19561 tataactgaa cacgttccca gtatatgtta tcaatatgta ttgcttgttt cgtttttgtc
    19621 attgttattc ccccattggt ttattaaatc gtccatttca atactgtttt tccccaagat
    19681 gtcgataaat ccatttcaaa cgcttggacg atatcttgca tcgtacatac attaatttca
    19741 tgtcctttta ataaggctaa cttttcaaca atgtctgggt acttatgata taaatcaaca
    19801 acttgctcaa aatctttaga gccgcttcga ctactaccaa tcaacgttaa tcctttttca
    19861 agtactaatc gtgtattcac ttccacgggt aattcactta cgcctaacaa agcaatactg
    19921 ccttctggtg aaatatgttc aactatttgt tgaagtgcaa cttgacttcc tttacctcca
    19981 acacattcaa atgcatgatc aattttaaga tcatctggta tttgatttac tgtaaagatg
    20041 tcatctacaa atgaaaaatg acttaattta tagtctgtct taccaaatac ataaatttta
    20101 gcttctgggt acaacttacg tagcaaaata gcagtaatat aacctaagtt accatcaccc
    20161 caaataccaa agctggtttt caaaggtata gatttacgtt caaatcgttg tatagcatga
    20221 taacttactg acactaattc tgtgtatgaa atcgtactca aatcaatgtc attaggcagc
    20281 ggaacgatac gatcatgtgc catcacaacg tagtcttgca taaaaccatc ataaccacta
    20341 gatctaaaat aactagaggc taagtaattc tccgcaataa tatgatgttg ctctgtaggt
    20401 gtattcggca ccattactac tttcgtacct ttttcaaata cccctgtact atcgaataca
    20461 acttcaccaa cagcttcatg aactaatgac attggtaatt tttggcgcag tacattttca
    20521 tctcttcgac ctgtgtaata cctttgatca gctgcacaaa tagacaagta taaaggtctt
    20581 acgatgacat gattaccata aatatcaaca ttattatatg tgacgtcgaa ctgtctcggt
    20641 gcaacgagtt gatatacttg attaatcatc ggcaatatca ccttgaataa tggcatttgc
    20701 tacttttaaa tcatacggtg ttgtcacttt aatgttgtat agttctccac gtaccaattt
    20761 aactggatgt ccagattcga caatgatttt acatgcatct gataagattt ctttttgttc
    20821 actacttaag gcgcgataac tatcttgtaa taatttaata ttaaatgatt gtggtgtttg
    20881 gccttgatac atttcattcc ttacagggat actgtgtatg ttctgtttat ctttagacat
    20941 tacaatcgta tcaattgctt caatgactgt atctactgca ccatattttg ctgctacttc
    21001 aatattctct ttaataatac gttgagttaa aaatggtctt acggcatcat gagttacaat
    21061 cacatcatca ttattaattc catttatatt gcgaatgtgg tcgataatgt tcataattgt
    21121 ttcgtttcga tccgtgccac ctgcaactac tttgacacgt tgatctgtaa tgttatattt
    21181 ttttaaaata tcctgtgtat gggaaatcca ctgtgctggc gttgcgataa taatctcatt
    21241 aaattcactc actaaaataa acttctcaat tgtatggatt aaaatcggtt tattatcaat
    21301 atctaaaaat tgttttggta atggcacgtt ccccattctc gaaccaatac ctcctgctaa
    21361 aatacctgca taaatcatgt tgtcctccat tctgtcatta catcatttcc atttatacat
    21421 tactgaccta tgcccgcaca taagcctaac ctattgctca cttgcctcta ttattaagcc
    21481 aaaggtagtt gtcacaatag tgtgataatt ttttataaaa atgtattttt gtaactgacc
    21541 attctaagtt gttttgccat gcagttaatc attaacactg acgatattaa attgttaaag
    21601 gtattaatgt ttactctttt tcaaattcat tattactgcc atcattttac catatattat
    21661 aataaattta tcttattaag tggctgtact tgattttcac tttaaaaatt atcaaatatt
    21721 gccatctcat tttaagtata caaaatgcaa aacaaccgat tcacaagcat atttcacaca
    21781 agtaaaccgg ctatttagca acgtatattc gaagatgaat tatttcgata gtatctgtag
    21841 accagacggc attcgcactt tcatagctat aactatacca gcgttttcgt cctcgaaggt
    21901 gcatactaat aaatcgtaaa catgacttta tcaaatcgtt ctttcttgtt aactaattta
    21961 tcaaatgtct ctgggccttt ttctaacggt aaaaaatgag aaataatagg ctttacatta
    22021 atatctttcg tcttcatata atgtaaggtt gccgtccact ctttgcccgg aaaatcactg
    22081 gacaaacagt tccaagagcc acatactgtc aactcgttac gcagaatttt ttcaaaatga
    22141 acgcgatcaa tctcaatatc atcatatggt attccgagta ataccacctc gccacctttt
    22201 ttaggtagcg tcaatatttg accaatcgta actttagcac ctgatgattc tatagctaaa
    22261 tcgatttgat tggcgtaatg attttcgatg aatttctcaa gatcttcttc ttttgaattg
    22321 attgtttgat gtgcgcccaa tgatgtagca atatctagtt tatgcgcatc tatatctata
    22381 gcgatgatat gtgcagcacc aaatattcgt gcccattgaa tagctaacaa tcctatactg
    22441 ccacacccca ttactgcaac agtcatacca ggttgtatat tcgatttata aaatccatgc
    22501 gcaacaacgg ctgatggctc aaccattgct gcttcaatgt aatcaacatt gtctggaacc
    22561 tttaaaacat tttgcgctgg caatttgaca tattccgcga acgatccagg ttcatatgag
    22621 ccaatgacga acaacttttc acatcgtgca tattcacctt tcaaacagta ctcacattga
    22681 taacaaggta tggctggaca acctgtcact ttgtcgccga ccttaacatg cgtaacatca
    22741 cttccaatgg catctacaac acctgaaaat tcatgaccaa atggcatacc ttgaatgtat
    22801 gggcccattt ttttgtatcg tgacgtgact gaaccacata tacccgttgc gcgcacttta
    22861 acaataacgt cattcgcact ttcaatgact ggcttatcat tatcctcata ccgtaaatct
    22921 tccacgccat ataatttcaa agctttcact tgtaaatcac ctcaactctg atttaattca
    22981 caactttttt ctttttaaaa atacctgtcg caaaataacc tgcaatgaca atggaattac
    23041 ttacgagtaa atgttccata taaaaatcag tgatttgtct taatggccca agcataaaag
    23101 ttagcattga ttctaccata ttaattctct ccttcatttt catctaaatc gagcggctta
    23161 agtaatgctt taataccttc gcctgatttt aaatgttgat acgcctcgtc ccatttcgaa
    23221 atatcatata tttttgtcac caaagcttca gcatttacta aaccatccgc cataagtcgc
    23281 aatgaaggtt cccaatctgc tggcttttga cttctactac caacaactgt tatttctttt
    23341 tgaatcactt tttccatatc aaatggaatt tcagcatcct taaaaatacc tatttgactg
    23401 tagaaacctt ttttgcgtaa aatatccaaa ccttgtcgtg ctgctggaac tgcacctgaa
    23461 cattcaacaa caacatctgc accgtaaccg tctgtaatgc cattgatata cgtttttaag
    23521 tctgtttgtt gtaaattgac tacataatcc atgtgcaatg cttctgcttt atctaatctg
    23581 actttgtcat tgtccaatcc agttaccaca acagttgcgc ctttactttt caacacttgt
    23641 gctacaagta atccgattgg cccaggtccc attacaactg ctacatcgcc tgaattgact
    23701 tgaatcttag aaacaccatg atgtgcacat gctaatggtt ctgtcatagc tgcagactga
    23761 tacgatactt cgtctggaat atgatgcaaa ctttcttcac gtgcaatgac ataattagta
    23821 aatgcgccat caacttgtgt tccaatacct tttcgatggt tgcataaatt atagtctttt
    23881 gattcacagt attcacactc attacaaata tagaatgtcg tttcagaagt gacacggtca
    23941 ccaactttaa aatctttaac gtctgctcca acttcaacga tttcaccaga aaattcatga
    24001 cctaatgtca ctggaaaatt aactttataa tgaccttcat aagtatgaat atctgtgcca
    24061 caaattcctg cataatgtac tttaatcttt actttatcat ctagcggtgt tgcaacttct
    24121 ttatcaagaa gttctaagtt gccatgtcct tctcttgttt ttactaaagc tttcaccaca
    24181 aacacctcga tttttaattg aatagactaa atagtttaaa gataagatag ttaacgatat
    24241 taccaccttg atcaatactt gaaatttcag atgaaccttt tggcatttgt acattcgtac
    24301 ctttcgccat atctgtgaaa atgggtgcta cgtctgttgc aatatatagt gaaattgcaa
    24361 tcataatcgt acccacaatg acagaatgaa taatgtttcc tcttgctgca ccaacaataa
    24421 acgcgacaac aaatggtata gttgctaagt caccaaaagg tagtacttgg tttcctggta
    24481 aaataacggc taataaaaca gtgataggta ctaaaattaa ggctgtcgaa ataaccgctg
    24541 gatgacctaa tgctacagcc gcatccaatc caatataaat ttcacgttcg ccaaaacgtt
    24601 tgtttagcca tgttcttgca gactctgaaa ctggcattaa accttccatt aagattttta
    24661 ccattctagg cattaatacc attactgcag ccattgacat tcctaaatta atgatgtctc
    24721 caggtttgta acctgctaac acaccaatac ctaaacctaa aattaagccg acaaagatag
    24781 attctccaaa tgcgccaaaa cgtttttgaa ttgtttcagg atcagcatct aacttattca
    24841 gaccgggtac tttttgtaac aatttaacta agtaaatacc tggtgcataa gaaattgtac
    24901 ttcctgtagc aatcgataca cctggtaaat caaagaactc actcatcatc ggtgctgtcc
    24961 aatctgctac tttcaaacag ataacttgga aaataactgc tgctaataac gcttgccaaa
    25021 tactgcctga tacggcataa accattgctg ctgtaaacgt ataatgccaa aaattccaaa
    25081 tatctacatt catcgtcttt gtcactttag ttactagcaa tacaacgtta actatgattc
    25141 cgagtggaat aataaatgct gcgacagatg atgcccaagc gatagatgat gttgctggcc
    25201 aacctacatc aatcacattc agactgacgc ctaaattttt aaccatcgct tgtgctgctg
    25261 gccctaaatt tttaactaat aaatcgatga ctaagaaaat ccctacaaaa gccacaccta
    25321 ttgttaaacc agacctaaat gccgctccaa ttttctgcct aaagaatagg ccaagcaaga
    25381 atatgacaac cggtaaaata acagttgcac ctaaatctaa aaatcccctt acaaaatcag
    25441 tgaagtaact catatttaaa ccctccctgt tatatatgca ttgtcacgat actttccgat
    25501 tgtgattaca tttgacgtta cagtcatttc aacgacaacc cttgctacat tcgactgcag
    25561 tccctttgaa ttacagtcac tgcgtttcta tgtcatcaac aatcatttgt cgtgatagtc
    25621 atttatatgc aatttgcata tatttatatg ttattgaacc acgttacata tcaattccgt
    25681 tatttttgta actctgttaa gatttgttgt tttgtttctt caataccaat accagttaag
    25741 aaattacgtg cgttgataac tgggaattta tattcttttt ttgtcattgc agttgtaact
    25801 aataaatctg cagtgtcttc ataaggtcca acttctgtaa ttttgatttg tttaatatct
    25861 actttaatat tgtgttcctt tgctatttcc tcaattgcat tatttactac tgttgacgtt
    25921 gcaatacctg caccacatgc tactaatact tgtttcattt tcaattcctc caattaattt
    25981 ttagttatat tccaaataat cattgattag tgttgctaaa attgtttcat ctttcgttcg
    26041 cagaatctgc tccaattttt cttcactttg aaaaatttgc atcaactgtt gtaacagctt
    26101 aagttgatca tctactttat ccattgctaa cataaaaacg attttcactt ctgtctgttg
    26161 atcaagtgtt cccatttcaa taaacggcac ttctttttct agaacagcca cacctatcgt
    26221 tctatggtta atatgttcga catctgtatg cggtatagcg accgaacata gatgcgttgg
    26281 taaaccagta gcaaattctt tttctctgtc gatgactgca tctttaaacg ttgacttcac
    26341 gaacccattt tgaaataaca catctgacat ttgtgacaat acggattctt tatcagttgc
    26401 cgacaaattg agcattatat tttctttatg cactaattgc tgtcccatcc attttccctc
    26461 gcttctttat ttgaataatt ttttaaaatc tcatttacat cagaattttt gcgactttgt
    26521 atgatgcgct taattgcatc attgtcttgc gccacatctc tcaattgtag taacgctctt
    26581 aagtgtgtca ctttatcaac agcagcaata ggtacaataa tatggattgc tgtgccatct
    26641 gacatgtata ttggttcttg taatatcaac atactcatcg ccgttttatg tacatgcttt
    26701 tcagagtatg catgtggaat agcaatattt tgcatgataa ccatatacga atcatcaaat
    26761 acctgttgca tctcatgaat atatttaata tcaataaaat gattagcaac taacacatca
    26821 cttgctttag caatagcttc atcaatattt tcaacatgat gtattctttt cacgtgcctt
    26881 gctggtatca agtcagctaa atctaatgtc ttattttgtg tgacaatcga tccattaatg
    26941 gttgaaattg aattataatt cgcaataaaa tcttctaaac catcacgtag ttctgtaatg
    27001 tcattaactg tcgttgtgcg ttcaattaat gccattaact tgtttatttc cttatcaatg
    27061 tcagccgatt ccttattaat gtacttcatc acttctttac gtaactttcg ttgctcattt
    27121 tcagataaag ctacttttgt gataaataat tttttatgtg ttaggacaaa cattggtgaa
    27181 aagacgatgt cataatctaa tgtgtaattt tcaaatgttc taagtgaaat cgcatctaag
    27241 aaaataattt ctggaaataa gtttcgcaac tcgtataaca tcatttgtga tactgacgtg
    27301 ccttgtgtac acacgataat agcttttatc ttgccatcga agttttcatc ttgacgtctc
    27361 aaactacctc cgaacaacat ggttaaatat gctatttcat tatcaggcaa cgattttccg
    27421 aaatattcag ttaacgattg gcatgattgt ttcaccatat gaaataagga ttgataattt
    27481 ccttgtaaag gattgattaa ttcatcacga tccgttaagt tatatttaat cctataaaaa
    27541 gcaggcgtta aatgtaacaa gagttgctgt gataatttct ccttatcttt aatgttaata
    27601 aaagtgattt gttcaaaatg gtgaatcatt tgagcgatgg ccatcgttaa attcgatatg
    27661 ctatctgatt cttgcaaatc agtccattgc acacttgttg aaagtaagtg taatgtcaaa
    27721 tataactttt ccgcttctgg caaatccggc tcatgttgcg tcataatctc cgttgcttga
    27781 tattctttcg tatccctcaa atactgataa ttaatattta atggattcat cacatgacca
    27841 ctttgaattc gtctacgaat cacacaaagg acataaggca gtgaactaag tgatttgtct
    27901 ataaagcgac tcttcaaaaa ttgttctacc tgtttgattt tgtctttttg atatgcgata
    27961 tcttcgaatg ttaagttgag cgcctttaaa acttcgcttt tagtaatatc atgattcaac
    28021 ctttgatcaa tcaatttaat gaagaaacgg cgaacttcaa attcatcacc aacaatttca
    28081 taaccatgtt ttcgagaata cttaagtgac aaaccatgat tttccaattg ctctttcaca
    28141 tgatttatat cgtgaatgac agtattttta ctgacttgta aatcaattga aaaatggttt
    28201 agagacattg cgttttcctt actaaaaagc atgagcatta aataataacg acgtgtttct
    28261 atgctaaaaa tgacattgtt accgtttaac atttgctgct ccgatacatc tcgcttgaat
    28321 aacgtcatga tttcagaact tacaataaaa tttccttggc ttgttctttc aagttttgga
    28381 taaccctctt gttcaagcca caaattgatt ttttgaatgc gatatcctag ttgtctacga
    28441 gataaaccaa atatcgattc aagttcttta ccatgaatag taggattcaa tacaatttct
    28501 ctgagtattt gctgattatc cccgttcatg ttcgatcctc ctttgagcat ctgagctcaa
    28561 tttatcatca atcgtcacac cgatgtacac actttgaaca catattttca aaatgagtat
    28621 gtacatcatt gtgatgtttc gacaacattc caattatatc ggtattcttt gtgattttaa
    28681 tcttttaaaa taaagcaatt gaaattttta catatatttt tgtgtttttt tgaagcattt
    28741 ttaacataca tatctcaatc attatcaaat tgtcatgacc attgtaatcc aatacaaaaa
    28801 ccctaaggac gcttatatca ggcgccttag ggctaactgt atctatttaa ttaagtatta
    28861 ttattcgtaa gtacgtaact tataatctat caagttccac acttcttcaa catcaactgc
    28921 tgtagcaaaa taagcattgg caggcttacc tgtaacatga tttaaatcga cagccatagt
    28981 accataagtt agtggacttt gatgttcaat gtcgatatta acgggtacca ttgtaaacaa
    29041 ttctggttgt aacaaataca aaattgtaca agcatcatgt attggaccac cgtccatatt
    29101 aaagtgagtc ttgtatgtct tcttaaagaa ttgcaataat tctacgacga actgtgcaac
    29161 aggattattg atactttcaa agcgttcaat cacgagatcg tcggctaaaa cttgatgtgt
    29221 tacatctaaa ccaaacacat ttatagtaat cccactttca aaaacgcgct tcgctgcttc
    29281 agcatcaacc caaatattga attctgctgt aggcgtccaa tttccaaatg taccaccacc
    29341 catcaaagta atagattcaa tatgctcagc gattcttggc tcacgaatca atgccgttgc
    29401 tacattcgta agaggacctg tcgctacaat tgttacaggt gtatcactcg tcatcacttt
    29461 gtttataatc atatctgatg ctggcattgc aactgcttga cgtgatggtg tcgacggtag
    29521 tttcgggcca tctaatccag attccccatg tatttcagaa gcaaaggcag ctgatttaat
    29581 taacggccta tccgcacctt tcgctactgc tatatcttga cgtcccataa tatccaatac
    29641 gttcaaggcg tttgtcgtat tcttgtcaac tgattgatta cctgcgactg ttgttacagc
    29701 taatatctct agtggactgt caattgcccc cgctaaaatt aatgctattg catcatcgtg
    29761 tcctggatca caatccataa taatctttct tttcatttat atatccacct ttcttaagtt
    29821 gttatcgata gcttatgtat atttatttat gtggtgaatc atgtttattt tgaaaaatag
    29881 ttttaacttt ctcatatttt tggatacaaa cactatttat ctattttatg gcttataaat
    29941 ttatccgata tgccttatca acctacctcg ctaaaaatag gatgtctaca tatctatacc
    30001 gacttttgtc aactcatttt cacaacaata taaacagcaa tttatatgat tgttacatga
    30061 ttcaaacaat ttttatgaaa aatattttca tacacagaat atatattgat attaaatttc
    30121 tcaaaagcta tattgagaat aattaggagg gatgttgatg aaatctttat ttgaaaaagc
    30181 acagcagttc ggcaagtcct ttatgctacc tatcgcaatc ttaccagctg caggtctatt
    30241 gttgggtatc ggtggtgcat taagtaatcc aaacaccgtt aaagcatacc ctattttaga
    30301 tattacctta ttacaaaata tttttacatt aatgtcagct gcaggtagta ttgttttcca
    30361 aaatttaccg gtcatctttg caattggtgt cgcaatcgga ttatctagaa gcgataaagg
    30421 tactgcaggt ttagctgcgc tgctcggttt cttaattatg aacgcaacta tgaatggctt
    30481 attaactatc acgggcacat tggcaaaaga tcagcttgca caaaatggac aaggcatggt
    30541 gctcggtata caaacggttg aaaccggtgt ttttggcggt attaccacag gtattatgac
    30601 cgcaatactt cacaacaaat atcacaaagt ggtattacca ccgtatttag gtttctttgg
    30661 tggctctaga tttgtcccta ttgtcacagc atttgccgca atctttttag gtgtattgat
    30721 gtttttcatt tggccaagca tacaagccgg catttatcat gttggtggat ttgtaacgaa
    30781 aacaggtgcc atcggtactt ttgtttatgg cttcatctta agattgttag gtccactcgg
    30841 tttacatcat attttttact taccgttttg gcagacggca cttggtggta ctttagaagt
    30901 caaagggcac ttagttcaag gtacgcagaa catcttcttt gctcaactcg gtgatccaga
    30961 tgtgacgaag tattattcag gtgtgtcacg ctttatgtca ggccgtttta ttacgatgat
    31021 gttcggctta tgtggtgccg cacttgcaat ttatcacaca gctaaacctg aacataaaaa
    31081 agttgtcggc ggtttaatgt tatccgctgc actcacttca tttttaacag gtattaccga
    31141 acctttagag tttagtttct tgtttgtcgc acctattctt tatgtaatcc atgccttctt
    31201 tgatggatta gcatttatga tggcagacat tttcaacatt acaattggtc aaaccttcag
    31261 tggaggcttt atcgatttct tactttttgg tgtgctacaa ggtaatagta aaacaaacta
    31321 cctatacgtc atacctattg gaattgtgtg gttctgtttg tattacatcg ttttcagatt
    31381 cttaattacg aaatttaatt tcaaaacacc tggtcgagaa gataaagctg cagcacaaca
    31441 agttgaggct actgaaagag cacaaactat tgttgctggt ttgggaggcc aagataacat
    31501 tgaaatcgtt gactgttgtg caacgagact acgcgtcaca cttcatcaaa atgacaaagt
    31561 cgataaagta ttactcgaaa gtactggtgc caaaggtgta atccagcaag gcactggtgt
    31621 gcaagtaatt tatgggcctc acgttacagt tatcaaaaat gaaattgaag aattgctcgg
    31681 ggattaagac taaccgaaat atcaacagaa ctaatggcaa cgatgtacga agtaagaagt
    31741 gacatcgttg cttttatttt taatgttaca tttgaagcat taagttcatc atgcactgta
    31801 gtgagcccgc aaatcgcctc tgctagacaa tcatcttaat gctatgatta acgcttaagt
    31861 gccagatttg aatttaattt caacaacgac tttcactaca ttaaaaatag ggctactcga
    31921 cacatatagt tgtatcaaat agccctttat acaatttttt ggggtaaggt tttacaattt
    31981 ttggaatggt atagatttta taaaaagtta tttaagttct tctgattcag ccataatatc
    32041 ttttaatgtt ttagctgaat gtgcgaactt gctttgttct tcgtcgttta atgggatttc
    32101 tacgacgttg cgaataccgt ttctattgat gactgctgga acaccaatgt aaacatcttc
    32161 ttcatcatat tcgccttcta ataatgctga tacagtcaat acggcatctt catttctgaa
    32221 aatcgcttca gtaattctag ctaatcccat tgcaacacca taataagtgg cacctttagc
    32281 ttgaataatg tcatatgctg catcacgtgt ttgaacaaaa atttgttcaa tttgcgcttt
    32341 gccctcagga cgttgttcaa gtaatgtctt caaaggttga cccgcaatat tagcgtgtga
    32401 ccatactggt aattcagtgt caccatgttc accaataatt tgagcatcga cactacgtgg
    32461 cgcaacatcg aacgcttcgc ttaacaataa tctaaagcgt gcagagtcta aaattgtacc
    32521 agaacctata acacgttctt taggtaaacc agagaatttc catgttgcat acgctaaaat
    32581 atcaacagga tttgtagcta ccaagaaaat accatcaaat tttgatgcca ttacttcacc
    32641 aacaattgat ttaaatattt tcaagttttt agatactaaa tctaaacgtg tttctccagg
    32701 tttttgtgca gcaccagcac agatgacaac tagatccgca tcatgacaat cactgtattc
    32761 gccagctttc acacgaactg ttgttggaga atatggtgtg gcatgtttta aatccataac
    32821 atctcctcga actttttcag tgtctaaatc aatgatgact aattcatcaa caatgctttg
    32881 gttcactaat gaaaatgcgt agcttgaacc tactgcacca ttacctatta atacaacttt
    32941 gttcccttta aatttgttca ttacaaaaac tcccttatga ttaattcact aacatacgtg
    33001 tagcttcaaa tatgttagtt taatgctgct tattgacgat acaaaagcaa ataaacatct
    33061 cttttatttt caacgcataa cttaaaaggt catgtgtcat ccgcttttaa gtttgtgatt
    33121 tatttcacat ataaaatgta acacgcatta agtactgggt caatattaaa ttgtgattta
    33181 tttcacattt tattttaatt tttacacctt tttaatttgt atacgattac atcttagatg
    33241 tctttagtct tcgtacttcg ccagtgattt tttacacttt cacattttta ttatcatgtt
    33301 taattttttc taagaaaaca acaatgtttt ttgaattagt caaataagtg cacgcaatcg
    33361 ttggggttca aatacacaat tgtacacaat gcttattgat aagtatttaa aaaattaaaa
    33421 atgtcataca attatcaaat ttgccatttt atttatattt tctcaaacca attaattgaa
    33481 tatcgaaatt tttagtagaa taatcaaagt agacagatta aaggaggagt atcatgctta
    33541 cagaacaaga gaaagacatt atcaaacaaa cggtgccttt acttaaagag aaaggaacag
    33601 aaattacgtc aatcttttat ccaaaaatgt ttaaagcgca tcctgaactt ttaaacatgt
    33661 ttaatcaaac gaaccaaaaa cgaggcatgc aatcttcagc attagcacaa gctgtaatgg
    33721 ccgcagcggt taatatcgat aacttaagtg ttattaagcc agtcattatg ccagtcgcat
    33781 ataaacactg tgcattacaa gtttatgctg agcattatcc aattgtgggg gaaaatttat
    33841 taaaagccat tcaagacgtg acaggattag aagaaaacga ccctgtcatt caagcttggg
    33901 cgaaagcata tggcgtcatt gcggatgtgt tcatccaaat tgaaaaagaa atttatgatc
    33961 aaatgatgtg gattggtttt aaacctttca aaattaccaa tattaaacaa gaatctgaag
    34021 acattaaatc atttacagtt gaaactgaag aatatgactt tagtgaattt acaccaggcc
    34081 aatacatcac agttgatgtt tctagtgata aacttccata tagagctaaa cgtcactatt
    34141 ctatcgtatc aggtgataaa aaccatttaa cttttggcgt taaacgtgat gtcacaacag
    34201 aacatgaagg cgaagtttca acaatattac acgacgagat taaagaaggc gatatgatta
    34261 atctagctgc gcctgtaggt ggattcgtat tagagaatac gactgaacca caacttttct
    34321 taggttcagg aattggtgtt acacctttag tagctatgta tgaagctgcc tctgccaaag
    34381 gtttagatac acagatggtt caagttgctg aaaatgaaca acatttacct ttcaaagaca
    34441 acttcaacag tatcgcaagc catcatgaca acgctaaatt atatacacac ttaaaagata
    34501 aacaaggcta tattggcgct gaagaattaa aagcattttt agcaaataaa cctgaaattt
    34561 atatctgtgg tggtacaaaa ttcttacaat ctatgattga agcacttaaa tctttaaatt
    34621 acgatatgga tcgcgtacac tacgaaacat ttattccaag actaagcgtt gcagtataac
    34681 tgagaaaaga ggtttagtac tcatatgaaa cttaatcaac gttacgttaa agtatttgca
    34741 ttatatttcg taagtattgt tactgcaaat attgttgtca aaaataacaa tttaatcaaa
    34801 acattgattc aaacacttgc cggttacacc gtctttgcag ttggtttgaa gtatttaact
    34861 aaacgtaaaa ataaataaca tatatacaaa aacagctatg actttacttt gtcatggctg
    34921 ttttttaatt gggagtggga cagtaatgat attttcgcaa aatttatttc gtcgtcccac
    34981 cacaacatgc attgatgtat gctcactgaa tttcataaga aaggagttca caagatgacc
    35041 gtagatattg gacggattta tgacaataaa gataataccg acgctattcg tatcctagtc
    35101 gatagagtct ggccgagagg tatttcgaaa agaactgcta acctagatta ttggttaaaa
    35161 gacattgccc cttctactga gttgcgacaa tggttccaac atgatcctaa actttttgga
    35221 gcttttaaag aaaaatatga aaaagaatta cgtgatcagg atgtgcaaaa agaggctttt
    35281 gaaaaattaa aggatattgt aaatcagcat aatcatgttc tattgttata ttcagcaaaa
    35341 gatactaaac ataaccaagc tgtagtacta cagcagttgc tcaatactta ggtatatatg
    35401 tttgtcttga atcactatac atgtcgctaa cttcatttct aatatttatt tttaaaaagc
    35461 ataattacta caattaattg aactttaata atcactaaac ttgaacaaca ttttactcta
    35521 acaaaataaa gttttaaaat attaattatt gggttttaca tagtaattag aaagagagtg
    35581 ttaatgaaat gaagtttaaa agactagcaa ctatattttc agcagtatta gtgttatcag
    35641 gatgtggctc aatgcattca tctggcaaag acttgaatat ttcgttaccg ttaaaaacaa
    35701 agtctattgc accttatgaa acagatgtac cagttaagat tggtgctgca gaatcattat
    35761 ttaaaacaaa tgatcaagga aaaatagaaa aagtattagt gaaatcgtat catcaaccaa
    35821 atgataaaac gttagatata gaattaaaag ataatattaa atttcaaaac ggtcaaaaat
    35881 tgactgcaga aaaagtgaaa tctagccttg aaaatagcat gaaaaaaagc gacttggtca
    35941 aatattcatt accaatatca tcaattaccg ctaaaggtca aaaactgaca attaaaacca
    36001 actacgctta ccctgaactt gtatctgaat tagctaatcc ttttatggca atttatgata
    36061 cagatgctaa atcagatgtt aatcaaactc ctgttggtac aggcccttac caaataaaag
    36121 attataagca atctcgaaaa atatcattgt cgaattttaa ggactattgg caaggtaaac
    36181 cgaaacttga tcatattact gtgacgtacc aagaagacgg caataatcgc gtcagaaatt
    36241 tagaatctca aaaagatgat ttaataactg atgtcccagt taataaagtt caagacatag
    36301 aaaataatca aaatttaaaa gtgtcaaaag aatctggatt tagaacttct ttacttatgt
    36361 ataatcatac taataaaaaa atgactaaat ccgttcgtga agcattagat catatcattg
    36421 atagacaagg tattgcagat catatttatc aaggttacgc gaaacctgca acgagtccat
    36481 ttaatgataa aattccatat attaaagaac ctaagttaac caaacaaaat atcgaacaag
    36541 caaaagcgtt attagctaaa gatggttata caaaagaaca ccctttaaaa attaagttaa
    36601 ttacgtatga cggtcgtcca gagctatcga aaattgcgca agtattacaa tcagatgcta
    36661 aaaaagctaa tattgaaatc gacattaaaa gtgttgatga catagaaggt tacttaaaag
    36721 accgttctgc ctgggatgca acgatgtata gtttcggaac gattcctcgt ggagatacag
    36781 gctatttctt taatcaagca tataaaaaag atggtgctat taataaagga gactacaata
    36841 atagcaacgt tgatgattta attaatcaat tgaatcatac tgtagatatt aaggaacgtc
    36901 acaatatttc taatgatatt attaaattat caagtcgaga tgtaccaaac agttatattg
    36961 cttacaacga tcaaatagtc gctgctaact ctaaggttaa aaattataaa gtaacacctg
    37021 aaggtatcta tttaatcgat tatcgaacaa cgattgaacg ataagggagt gtgggacatt
    37081 gatttatgtc tcagccccgc ttcaactata aaaaccacgc cgaggtcatt caatatgatt
    37141 atggcgtggt ttaatttgct tatatgattg tattactttc tgtttgatga atttcaataa
    37201 aatgattatt acatattttt agtgaatcat gttcatttta tataaatcta attgtcacta
    37261 tttgtttaac gtgaaacact ttttaactcc aaaaagtatt ccacttccac tcttttagag
    37321 acaaattata aaaatagctt atgtcacaaa catatgagca acataagctt taattattat
    37381 tcgtctactt ttttctgttg ttctttaaat tctttctgca gtaaattaac ttgttttaaa
    37441 cctgccccca ttaaaatgaa tacaagtatc cacacaataa cgattaaaat aaatattttc
    37501 aacgtatcac tgccaagtac agttaaagat gtatcccaaa tgccatgtaa accaacggct
    37561 gataaaaaga atattaaaaa gcgtttatca aaaatatctt tgaattcaaa gccatgctgt
    37621 tctttcgcaa taactattgc agcaccaaca atcgctgacc aaactaaatg gccaccaatc
    37681 gcagtccacg cacgtgtgaa gacaatatct aataatggga cattttcccc taaagcgaaa
    37741 ttcaaaatat aacctgctga ttcaaaaact gcgaaccctg caccaatagc agcaccgatt
    37801 aataatccat tcaaaatctt atttgttttc aatttattga cgaaataaac aataatgagt
    37861 gcttttccag tttcttcaac taatcctact aaaaatgcat cgaaaaatgt taaagaacca
    37921 aacctttcga attgatcact aaaaacgaca aatctatata ataccatcgt acttagtaat
    37981 gaaaatactc cgccaataaa gaacatgata ataacttcaa aaatgctaat atttttaaac
    38041 gcatttgatt cataaaagaa gaacaaaccc gataatggta ctgttaaagc cccaataaaa
    38101 atgagacccg gaatcgcgtt agtgttatta aaaatcgctg ccatgaccca taatccaata
    38161 aatgttactg tgaaagcgat gaatactcga gaaaagagcc atggcttccc ccattcttct
    38221 gatatgtcac aaattgctgg cgtagtttta gcagtacccg ctataaatat ttcatctgct
    38281 tcgtttttag tatgtggctt aaatacttct gaaaacatat cttttaaatt aagatttaag
    38341 ctttcatcat tgccggctag tctaccgatt gatttggttg cattatcaaa taaacttctt
    38401 gcttcgtttt ttaaatctgt attttgcgct gtttcatgcg ctttggcttc catttgttta
    38461 tcgatagatt cattatgtat gtcggacgtc ttagttgatt gtgtacttgc tgatgacatc
    38521 ccctcttcac ctgtattagg tgcaactgat tgcgtttgtg ttgtctcttc tttttctgta
    38581 tttcttcgat gattaagacc ttccatagac ttacctactt tcacttttca taataaaact
    38641 attttaattt aatattgatg gattttccat atatttatat aactactttg ttcgattgtg
    38701 tacattcgtt tttttactca ttttaaaata caactcacat cttacgcttg agtaataaaa
    38761 tcaagtattc ggaaaatggc ctgcctattc tgtttaggca cctcaaaggc taatatgtcc
    38821 tccgccgatt gctctaaaat agaatgattg atgtattggg catcatttag tactatttct
    38881 ctgacatcgt ctggaccagg ctcaaaatga aattgtaatc caatcacatg atgatcgatg
    38941 ataaatcctt ggtttctaat atgattccct gaaaataata attctgcttg ttgcggtatt
    39001 tgaaacatat cctcatgcca atgtagtgcc ttcaatcgac ttggtatatt cggaatgatt
    39061 tctgattcta agtaaacatc atcccaacct acttccttta ctggtgattt taacaccgca
    39121 taacctaatg ctttcgaaat ttgttgtgca ccaaagcaag caccataaat tggtttgttt
    39181 tgtgccatca atactaaaat taattcgcgc tctgattgaa tccaaggcat ctcatcgtct
    39241 ggattcattg gcccaccaag tatcactaac atatctgttt cttccgcaag aggtagcacg
    39301 ccatcattca tatatgggtg ataaatatag acttcgtgcc cgctttcctt cgcccactca
    39361 cctatgtatc caacaccttc atttggtgta tgttgtaaaa cattgactct catatgttca
    39421 acatctcctt caactctcca atgatttcat cagttacatt atacaccact gattgtacgc
    39481 tgatcatcct caccttactg atgcatcaaa atgataatta gtctttgcat tttttaaata
    39541 aacatgggtt gttttttata ttccgagcaa tatttttata taagtatttt aatgatattc
    39601 aattcattac aaacccttga tattacaatt gttatcaacc atcaaaatgt gtctatactg
    39661 tgtctattat cagaataaaa agatatttct aattgatttt aaatgtcgtt atgttatatt
    39721 tcttgtaagg gtttatacaa agtgtaaaaa cgctatattt tatcaaatgt gatggaggtg
    39781 acttgcttga aacaaatcac atggcacgac ttacaacata tcattaaaga tggtgatgtg
    39841 attggtttac cagcattagc tgtagccaac ttacccgccg aagttctacg tgctgtgtta
    39901 gcgcaacatg acacatatca tacgcccaat gatttaacgt ttatattagc gaatgatatc
    39961 catagtttag gtgccgcacc ggatttagat gattttatag aacgtcgcat gattaaacgt
    40021 gtcattatga gtattttaac ggcttcttcc aaaacggcac aagcaatgaa aaataatgac
    40081 attgaagctt attttttacc acaaggtatc attgcaactc attatcgtca gagtaatcaa
    40141 ttattacctg gagttattac taaaatcgga ttaaacacag ctgttgatcc tagatacggt
    40201 ggcggtaaag taaatacacg aacaactgat gatttagttt cattagtaac catcaacgat
    40261 gaaacatact tacactacac attccctagc gttgatgtgg cactactgag aggaacatac
    40321 gcagatcaac aaggtaacat ttatttaact caagaagcgt acttgagcga gtgttatcat
    40381 gtcgcattaa acacgaaagc caatcatggg aaagttattg tacaagttaa agctttagtt
    40441 gacgactatc aactaaagcc gaatgaagtt gttatcccag gaaatcttgt cgattatgta
    40501 tacgtcacag aagatgaaaa gaatcaccgt caagtaattc agagtcatta tttaccagcc
    40561 ttgtctggag aagaacgaat tgatggaata cctgaacccg cattaccttt taatagtcgc
    40621 aaattgattc tccgacgtgc tgctcagttt ttaacttatg gcgatacaat tagcatcggt
    40681 tatggcatca ataatgaact ctctaattta ttgcatgaag aatgtgttga acatgatgtg
    40741 caaccgattt tagatgttgg cattttcggt ggattcgttg ggagtcgtga acattttggt
    40801 atgaattaca atgcagatgt gcgcatgcct catgatcgag catgggattt tatttataac
    40861 aatggtgtat cagttgccta tcttagcttt gctgaagttg atcaacacgg caatgtcaac
    40921 gtgtcatact tcaatgaccg actaaatgga tgtggcggct ttatagacat tacgcaatct
    40981 gtaaataaaa ttatcttttc aggtactttt gtagccggta gtcatgtctc atgtcataat
    41041 caacgattaa acattgaaac tgaaggacaa aaccagaaat ttgtatcaga tgtgagccat
    41101 atcgacttta atgcacaata ttcacaatca ctcgagcaag aagtctattt tgttactgat
    41161 cgtgcagtat tcgagctcac caatcaaggc ttgaaactaa ttgaaattgc tccaggtctt
    41221 gatttgcata aagatatttt gaatcaaatg gcttttaaac caattattgc tgatcattta
    41281 aaattaattg ataccagcat ttacaaagaa aaatggggac aacttaaaca atcaattcat
    41341 aaagtatgaa agtgaagcta aagggggtat actaatgaat ttcgattgga taaaaacacg
    41401 ttcagacttc gatgatgaca agcctgccgt tattgatcac gcaaaacaaa catcttggac
    41461 ataccaacaa ctcaatgcac gcgctgataa tatggcacat tatttaacat ctcaaggtgt
    41521 taaaaaaggc gatgttatcg gtatttttgc gccaaatgat attgcaatat tagatttact
    41581 atttgcttgt tttaaaacag gtgcggtttt tttaccattg aattggcggc ttaacccaaa
    41641 agaaattgca gccattgtgg aagatgcaca attaaaactg ctcttctatg ctgaaaaaca
    41701 tttaagttca ctcaccgata ttgaccaaaa cttattgcat atggatattg atgtagcgca
    41761 atatgatgaa atcgtaaatc cagattatca ccaacctttt caagcaacac ctgttgaacc
    41821 acaagatctt gcagcattaa tttatacaag tggtacaacc ggatcaccta aaggtgtgat
    41881 gttctcatat gaatcatttg ttcataacgg cgcaaactta gagctgacgt ataagttcaa
    41941 ttcaaactat attacgattg tatcaacacc aatgttccat gttttagggt ttaacgatac
    42001 tgtattacca gtattaatgt caggtggcac acttattctt caacgttact ttaacggcga
    42061 agaattgaat gacatgattg cacaatatca ccctacattt attatcatga ttccgacaat
    42121 gtattatagt acgctacgtg ctagtaattt taatcctgaa aattttaaag ctatggatta
    42181 tatcatccaa ggtggttcac aaccattacc aagtatccaa gcagctttta aacaatatgg
    42241 cataaacatt attaacggct atggtttaac tgaagcacct cttgtacttg ttaatacacc
    42301 ggaaaattca aaacgtaagc caatgagtat tggtaaagca gtcatgttcg ttgatgcacg
    42361 tatccttgat gataacggtg aggaagtacc tactggtgag attggcgaac ttgcaattaa
    42421 ggctaaaaat gtcacgccag gatattggaa taaaccagca gagactgcca aagcatttca
    42481 tggtcgttat ttattaactg gtgacttagc gaagatggac gacgatggcg atatatttat
    42541 tattgaccgc aaaaaagaat taatcataac tggtggcgaa aatgtcttac catccgaagt
    42601 cgaaaatgct ttagctgagc atccactagt agaccggtgt gtggtcgttg gctatgatca
    42661 cccaaaatat ggtgaatcaa ttgctgcagc cattatactt cgcgaagatg aacctcatta
    42721 cgctgaaatt ttagatcaac atatgcgaag tcgtttagca ggttataaag tcccaagaat
    42781 gtatgtacca gtgacacata tgccgttaaa cagtacgcag aaaccagata aacttgcgat
    42841 tcgacaaatg atgaatgaca aagtctcaca aacactttaa aggtgataaa aatttttagt
    42901 atttagtgta agcgtttaca aataaagcgt gttgtttttg aattaaatgc atttcacatt
    42961 agtattcata ttatttttag gaggaattta tatgacattt gaaaaagaaa cagtcttaaa
    43021 aacattattt cctgaagatg tacttagtat tgctaaaggt ttaacagacg gtgaagtcga
    43081 atttttacaa caagtagatt cattgctaga aagtaagtac cgtgaaaata ttaatcaaca
    43141 ttggatagac gctactgtac ccgaggactt ttttaaaaat ctgggagaat taaattattt
    43201 taacaatcca ttactttaca aggatcgtcc aaacgccaaa atgcctagtc aactatttca
    43261 gtttttcatg tcttacctac tcgcgcgatt tgatatttcc ttagctaccc tactcggtgt
    43321 tcaccaaggt ttagggcata acactttcta tttcggaggt agcaaagaac aaattgcgaa
    43381 atatgtacct aaattacagt cacatgaact gcgtacatgc tttgctttaa ctgaaccaga
    43441 acacggttcg gacgttgcgg gaggtcttga aacagtcgct gaacgccagg gcgatacttg
    43501 ggttatcaat ggtgaaaaga aatggattgg tggtgcacat gtatctgatg tcattccagt
    43561 attcgcagta aataaagaaa ctggcaaacc ccattgcttt gtagtcagac cagaacaaga
    43621 tggcgtcgat attgaagtca ttgataataa aatcgcactt cgcattgttc ctaacgcact
    43681 aattaaatta actaatgtca aagtagatga agcggatcgc ttacaaaaca taacaagctt
    43741 taaagatatt gccaaaattc tttattcaac gagagcaggc gttgcttata tggctacagg
    43801 tggtatggct ggcgctttac gtgccacatt agattatgtc actgagcgta agcaattcgg
    43861 caaaccaatt agtaaatatc agttaataca agaaaagcta gcaatgatgc aaggtaattt
    43921 agctcaagca atggcaacat gtgctcaatt agctaatatg caagcacatg gtgaatatga
    43981 cgaggttgca acttcaacgg cgaagatgat gaatgcctta cgtttgcgtg agacagtagc
    44041 tatgggccgc ggtattacag gtggtaatgg catactagct gacgattatg atattgcacg
    44101 tttcttctct gatgcagaag cgatttacac gtacgaaggt acacatgaaa ttaatgcctt
    44161 agtaattgga cgcgctttga ctggagattc tgctttcgta taaatagcaa agaattatat
    44221 aagatacagt aatttcacta aaaacagact tattttaagc ataaagcttt ttccttaaat
    44281 aagaggctaa gatgactgtc aaagatacct aattaatttt ataaaatagc aacgttattc
    44341 caattatctt aatggttatc ttatcctcaa ctaaattgga ggaatcacta tgacaattaa
    44401 taaagtaacc gttcttggcg caggcacaat gggcgctcaa ctggcagcac tctttgtgaa
    44461 tgctggactt aaagtaaaac tattagatat tgtagtagac aaaaacgatc caaatctcat
    44521 tgcgaaaaaa tcttacgata aaattacaga taagaaacgg ccgctactat tcgacttaaa
    44581 tctagcgagt catttaacat atggtaattt tgatgatgac ttggtaaatg atgatgctga
    44641 tttatatatc gaagcagtca aagaagatat tgaaattaag catgctgttt ggcaacaagt
    44701 tctacaacat gctaaagaag atgctttatt cgctacaaat acatcaggta ttccaattaa
    44761 tgcgattgct caagtattta acgagaagga tcaagaacga ttctttggtc tacatttctt
    44821 taacccacca cgtattatga aattagtgga gttaatacct acgtcacaca cgaaggaatc
    44881 tatcatatta gatgtaaaaa atttcgcgca aaatgtgtta ggtaaaggtg tcattgtcgt
    44941 caatgatgta cctggctttg tcgcaaatag agtcggcacg caaacaatga atgatattat
    45001 gtatcgcgcc gagcaacaca agttaagcat tgtagatgtg gatgctttaa ctggacaagc
    45061 gattggtcgt cctaaaacag gtacatatgc gctatctgac ctagtcggtt tagatattgc
    45121 agtgtctgta attaaaggca tgcaacaagt acctgaagaa acaccttatt ttcatgatgt
    45181 caaaattgta aatacgttgt ttgacaatgg cgcactcgga cgtaaaacga aacaaggatt
    45241 ttacaaaaag gataaagaaa ctaaagctcg acttgtttac gatgttgaaa aacaagatta
    45301 tgtacctgta tcgcaaccac aattaccaat tttaaatgaa tttaataaag acttagcgca
    45361 taaccttgat gtcatattca atgcgcaaga cgaagcggga ctatttttat gggagacatt
    45421 acgtaataat ttctattact ctgctatcaa tgtacctaaa gctaccgatg atttccgaga
    45481 catagaccgt gcgcttgtct gggggttcaa ctggaaactt ggtccattcc aattatggga
    45541 tgcaatggga tatgtacgtg ttaaaaaacg tatggaagac gaatttggag acttaccaca
    45601 atggattagt gatttagatg gtggctttta taaaaaagat gagaccatcg aatatgcaac
    45661 acctgtttct cacttcgtaa aagatgaact ttgggataaa ggtgatgcca aactttccgt
    45721 aactcatgat gatcaactgt tactgaaatt acaaagtaaa aataatgtca ttaccgatga
    45781 attcaacgat gcgttagttg atgcgattga tttactggaa aatgaccatt acacaagtat
    45841 ggttatttat gcagatggta acaatttcag tgtgggtgct aaccttttct taatgaaaaa
    45901 ggcgcatgaa gacggtcttg tagatgatgt cgttgcacaa tcaattgata aattacatta
    45961 tagctttaat cgtttgaagt atagtttgaa accagtagtc acagctgttc aaggtcgtgc
    46021 cttaggcggt ggctgtgagc ttgtacttta ctcacctatt gttgtcgctg caagtgaaac
    46081 gtatatcggt cttgttgaag caggcgttgg cttattaccg agtggcggtg gccttgcaga
    46141 aatggctgat cgcatattac gcacatcgca taagtttgat gacaaacaag cttccatgac
    46201 aaaagtactg acgaatatcg catttgcgaa agtctctaca aatgcctttg aggcacgtcg
    46261 ttatggttat ttacgtgata cagatacgat tattttcaat acagcacaac gtgtcgaagt
    46321 tgcgctcaaa cgtgcgaaat atgaagcaga aacaaactat attccgaatc ctagacatca
    46381 atatatcgct ttaggtgaag acttcaaagc atttatccaa ggacaattag atgcgcaaag
    46441 acggggtcat tttattagcg accatgatta tcatatcgcc ttaaatattg ccacaatttt
    46501 agcgggtggt gatttaccaa gaaatacatt tatcaatcaa cgttacattc aatcgttgga
    46561 gaaaattggc tttattgact tactaaaatc taaaaaatca tatgaaagaa ttgcacatat
    46621 gttaaaaact ggtaagccat tacgtaatta aaagatagtc attaagagag gatgataacc
    46681 atgcaagaag catacattgt agcttatggg cgttcagccg cagcgaaagc aaagcaaggc
    46741 gcattattcc acgaaagacc tgatgatgtc gcagccaaag tattacaagg cgtattgaaa
    46801 cgtattgacg gaaaattcaa taagaatatg attgaagatg tcattgttgg tacggctttt
    46861 ccagaaggat tacaaggaca aaacattgca cgaacgattg cattgcgtac gggattatct
    46921 gacacggtac cgggtcaaac agtgaatcgc tactgctcat caggattaca aaccatcgcg
    46981 attgcagcca atcaaattat ggctggtcaa ggagatatac ttgtagctgg tggcgttgaa
    47041 ttgatgagtg ccgtaccaat gggtggcaac gagcccacaa acaatcccac cttacaatat
    47101 gatgatatag gtgcgtcata tcctatgggt ttaactgctg aaaatgtagc atcccaattt
    47161 gacgtatcac gcgaagatca agatgcttat gctgtcagaa gtcatcaacg tgcctatgac
    47221 gcacaacgtg atggtcggtt caaaaatgaa attattccaa tacaagtaaa ctcagttgaa
    47281 tatacaaacg caggaccaaa agtacacaca aatatctttg accaagatga atttatacga
    47341 cctgacacca cgatggaggc attagccaaa ttacgtacag tatttaaagc tgacggcact
    47401 gtgactgcgg gaacatctgc cccactttct gatggtgcag gatttgtagt tttaatgtct
    47461 ggagataaag tgaaagaact cggcgtgaca cctattgcac gattcgttgg ttataaggca
    47521 gtaggcgttg acccgaaaat tatgggtatt gggcctgcat atgcgattcc tgaagtattg
    47581 tcactcagca atctatctgt tgaagatatt gatttgatcg aattgaacga agcatttgct
    47641 tctcaaacga ttgcatctat taaagaagta ggtctagata tatcacgtac gaatgtgaat
    47701 ggtggcgcta ttgctttagg tcatccatta ggtgctacag gcgcaatgtt aaccgcgcgt
    47761 ttacttaatg aaatgggtag acgtcccgat agccgttacg gcatggttac gatgtgtatt
    47821 ggtgtcggta tgggtgcagc tgctatattt gagtatgtgc gttagaatgg ttgattttgg
    47881 atgaagcgga ttcgttttgt tattaaatga agtaggctga agttgaagca ggttgaagtt
    47941 gaagcgggtt gaagcaattt cgttttatta atgaagctat gtgaaacata gtgattgaac
    48001 aaaaaagtgg tttaatggga tggtgggtat ttccgtttta gaatttaaca tttacacgtc
    48061 taattttaat cattgtttta aattttatga atcgaagccc tttgatttaa taatatttgc
    48121 taatgctagt aacttatctg attgttcatg tttaaaataa agaaaaccac tcacatcagt
    48181 gtgtgttcga actagacttg taagttccag ttcggtacga ctttctaaag caattattat
    48241 tgctgtgatt gtcgtatatc acttagatgt gcgtggttta ttttaatagg ttagtaatat
    48301 attaggtcat gttatgttta agactataat gaataaataa tttagaaata tgcttccgat
    48361 tgttcgatgc tttaattcag ttagaagcat catagaatgc atgattactg ttgtaaagat
    48421 acgtaatgtt ttgtattgac tgtatatctt tggatagagt tacaaactta ttttgttact
    48481 ctaggcccat atgtcgcagt accatctgca tgtgttgtta cattgtatgc atttgtttcg
    48541 cttggcttct tgtatgtcgg gcgagctccg tatgatactt ggccatttcc gtgtgttgtt
    48601 acgttatatg cgtttgtttt gcttggcttg ttttgtgtcg gacgagcgcc atatgatact
    48661 tgaccatttg catgtgttgt tacgttgtat gcatttgttt cgcttgcctt gttttgtgtc
    48721 ggacgagcgc catatgatac ttgaccgttt gcatgtgttg ttacgttata tgcattcgtt
    48781 tcgcttggct tcttgtatgt cggacgagct ccgtatgata cttgaccgtt tgcatgtgtt
    48841 gttacgttat atgcgtttgt tttgcttggc ttgttttgtg ttggacgagc gccatatgtt
    48901 actgtgccat cttgatttgt cgttacgttg tatgcgtttg tttctgatgg cttattgaat
    48961 cttggtctcg cttcatatcc aaatgttcca tcgttgtatt cacggatacc tgtaccagca
    49021 tctctatatt taacatattt aggtgttttg ttaaattgcg gtctcggacc atattgagaa
    49081 gcttctgttg tttcagttgc ttgaggttta acttcaatat cacttgattc tccttgagta
    49141 ccttgtaacg ttgattcagt accttgtggt tttatttcaa gtttagatga gctaccttca
    49201 agaccttcta aaatagggtt cgttgtcgtc ggttgagtat aattatcgct taaagatggt
    49261 ctgttttgtt ccattgttgg gaaatctgga ccttgaacga tttcaccttg taacgtttta
    49321 ttttccatag ttggatagtc tggacctttt acaatttcac ctgtaattgt gccctgtgga
    49381 attttaacta atggttgtgt tgtttcttca gctttaccag ccgtagtttt aacctcttgc
    49441 tggttcccaa ctttaggtaa ttgaggttct tcaactttct tctcttcttt tacaaaagga
    49501 gattttgtta cagtttcctc gtattttttg acagttttat ttttccaaga ttcgtctgct
    49561 ttttcaactg cttctcttgt ttctttaact aacttatcaa aattttcttt attctctttt
    49621 ttctttgtat aatcatgaat attggggtca tatttcttta ttgttgtagg tctattctga
    49681 tttgtttcca taaagaaatc atcgactatt gaatttaagt cttccatcat ttcttttttt
    49741 atacgttcat tagtgattct attcgggtta tgcacgtcac ctagtattat gtctaatttt
    49801 gctcgtaatt ctttagcatg tataccaaat ttttcatgac tataatacgc tgcaaaaact
    49861 gtatctattt cactaacaaa ttcatatatt ttatcagttt cttgtttttc agtattttcg
    49921 tcataaggct ttaagtcttc atttttagat tgaatatctc ttacttcatt attaaatttt
    49981 tccacagcgt cttttaatga atttgagatt tcattatatt cattcattgt taaatagtaa
    50041 acattatact tatgaaatga atacattttt gaattatcgt ttgggtaagt tgctttatac
    50101 cattttttat aataatcgta ttcatctatt tttttcttta ataaatattg atcttctcct
    50161 aatatccttt ccattaattt atcttttgcc tctttatatt cattaccacc atattgatac
    50221 tcatctgtta atgccaatgc acttgaaaac tgcttttcta gagcttctat tttttcccaa
    50281 taatatctgc tatctattaa tgtcccattt ttactctctt ttttaacttg tgatttccca
    50341 ttataatcct ttgttactat cgcatctgct ttgttatccc atgtaaataa gctagatgca
    50401 actgctaatg cgcctagcga aattatttgc tttttcataa ttttttaatt cctccaaaat
    50461 gtaattgccc aatctacatt aaagaaacaa aatattaaaa gacattaact atatattaac
    50521 tagaataaac aaagcattaa ctatcttttt gttatagtta attagctttg caatatacaa
    50581 tagtgtataa tttttttgat taatgtacat caaaggagta acaaagcatg acaacacaaa
    50641 tgaaaatcaa aacatattta gttgctggta ttaaagcggc gctccttgat acgactggta
    50701 ttaaattagc aagcaaatct gaaactacat cacatacgta tcaacatcaa gcgcttgtag
    50761 atcaattata tgaattaata gcaaacactg acttaaataa attatcgtac ctaaatttag
    50821 atgcgtttca aaaacgcgat attttagctg cgcactatat tgcaaaatca gctatacgca
    50881 ctaaaaattt ggatcaaatg actaaagcga aacatagatt agaaagtatt tacgattcaa
    50941 tttctaaccc tttgcattca caaaaaaatt aataattcac caataaatca tgtaagtgtt
    51001 tgtgacgcca aatttcctta taaatccttg tcatatgatt ataaacgaat gaaacgattg
    51061 cctatcccat aggtgacaat gttaaaaaga cctctgaagg tatcatcttg ataactttag
    51121 aggtctttgt ttatattatt caaacaaaat tcttatagaa cgatcgaagt atgtttcgtc
    51181 tttcttttct tctttaatct gatcagctaa tgctgggtca tctgtgataa taccatcaac
    51241 attggtttgt aagtatttcg ttaaatcttc ttcgccgtta atggtccaag tatagacttc
    51301 tttattttcc atgtgtgctt gattaacaag tcttggcgaa taagaaaaat cttcgatgac
    51361 aaagaaatct aatgatgttt ctttaaaatg accaaactgt aacgggatga tataaccaca
    51421 cttgagatat ggcgcttctt tttttaactt agtcatcaca tcataatcca atgacatcac
    51481 acgatattga tgttcaacac catgcttttt caaaatatca ataacacgtt gtgtataatc
    51541 tgctggttct ttaccatgtg gctttaactc tactagtagc ttcacatttg attgtttagc
    51601 cgtttcaata aattcgtcta aggataccag ttttgcttca tgtccatttt gacgcatttt
    51661 caaaccgacg acatctttga aattagattc agaaatgttt ttattaacac ctgttaaacg
    51721 tttcaaattg ttatcatgac taacaacaaa ttgtttatct ttcgtcataa ttgtatctaa
    51781 ctcaatatat tcgacattcg cttttgcagc agctttcaat gacggaatag aattttcaac
    51841 gcctttatct tcgaaaccac gatggccaat aatggatata tttgtattga tagtattatt
    51901 gtaaagtaag tacatgttat aaccgataaa acatgtcact gcaagcacca ttgaaattat
    51961 aaagaaccta gatttccgtt tcggttttgg gtatttaaat tctaagcccg gttggtctaa
    52021 tacattctct tgttttaagt gcagtactaa cacactgatt aatgataatt tcgtaaataa
    52081 ataatagaag aacaatgcgc ttttcaatac aacaaataaa attgatgaga ctaaaaactt
    52141 atctccttct tcatctacac aaatagcaag atatgttgct cctgaaataa ttaatgttaa
    52201 aatcgcacca atgatgagtt ccaatataac tatttctata acaagtcgaa acttatttcg
    52261 cttcgtaatt tgccaactta gtctcatatt tttaaataac gactggcggt ttaaaatcgt
    52321 taacggtaga gtaaatatta atttaaagtt taatataaat acagcaatca taaaggtacc
    52381 gtaaatgatt ataccttttg tcgttttcat aagttcttcc gttaaaaatt taggtatgta
    52441 aatatttttt gttaatactg aacttagtcc taggttagca atgggtatca ttaacattaa
    52501 ataaatgaca aagaaaataa ctggtacacc tatgagttta cgcacattta caaaggcatt
    52561 tttaaaaatg gatttaaatg taataatctg tcgatcaaag ccggcataaa ccatataaac
    52621 taacaatgaa aactctacat aaatcagaaa ggcaacactt aatatgaata taataagaag
    52681 tatcacactg gcagggtgac ttacgatttc catccaattg ttaatcgtaa gttggctttg
    52741 cccagctact tttaacatca tattaaatag taaaattaag tatgtactac taataaaaat
    52801 catgattaac tgcaatagta aggcgttaat gctaaaacgc cctttatttt gatacagtaa
    52861 tttaaatact gcccatatat ctttactaat tctcttcata atcacgctcc gcattgcttt
    52921 aatattaagt ttcatcttaa tatttttcat tactcagggt caataaaaat ttgaaaagac
    52981 tcatattcat atgcaagtag caaataataa cccattcaac atcagctaaa tgatgatatt
    53041 ggaaccccac ctttaacaag gcttcacatt ctttatcagc atagctactt acaaaaatgt
    53101 cttccttcaa ccattgtaga agttgtctca tatacctact acgtcttgct attactctat
    53161 actcaattga aaaagaagca tatgcccctt cactcttgaa gttacatatg ctttcttttc
    53221 ggtctgaatt gtatttataa ttcaacggga attttccctt tgaagttaac ataacggtag
    53281 gctgctttaa cagcttcatc atcgggcgct tcgacatctt ctaattcata tgcaatgccc
    53341 aatgttttcc acttatgaac acctaactga tgatatggca gaatttcaaa cttttcgacg
    53401 ttatcaagag aattaataaa ttcccctagt ttaattaaat cgtctttatc atcagaataa
    53461 ccaggcacaa ggacatgtcg aatccataca ggttgtttca tatctgacag tttgcgcgcg
    53521 aagttaagga tgtgtgtatt aggctttccc gtcaatctaa tatgtttgtc attatcaata
    53581 tgttttatat ctaataatat caagtctgta tgtttttgta attcttcaaa atgcctttga
    53641 aatgcttttg tatcattagc acatccagcc gatgtgtcta agcaagtgtg cacaccattt
    53701 tcttttaatt ctgcaaataa tttttctaag aatggcattt gtaacaatgg ttcgccacca
    53761 ctgactgtta caccgccacc cgatgcatca aagtatggtt tgtatggtaa tatttcattc
    53821 accatttcat caactgtgac ttctcttgat ggctcactaa ttttccaagt atctggattg
    53881 tggcaataca agcatctaag taagcatcct tgtgtaaata atatatatct taatcccggt
    53941 ccatcgacag tacctaaact ttcgacagaa tgtaagtgtc ccttaagcat agtgctccca
    54001 ccttaaattt tgttacatac tttcatggaa tgtacgagaa attacatcta attgttgttc
    54061 acgtgttaat ttaatgaagt taacagcgta accagataca cggattgtta actgtggata
    54121 ttcttctgga tgttccattg catctattaa tgtttcacgg ttaaatacgt taatatttaa
    54181 gtggtgacca cattgcattg cgtaaccatc taacatacta gttaagttac ggttttgatc
    54241 ttctggttct ttacctaatg attttggtac gatactgaat gtatttgaaa taccatcttt
    54301 acagcaatcg taagggatct tagctacaga acttaatgaa gataatgcac ctttttggtc
    54361 acggccatgc attgggtttg cacctggtgc aaatggttcg ccagctttac gtccgtctgg
    54421 tgtgttacca gttttcttac cgtatacaac gtttgaagta attgttaata cactcattgt
    54481 atgttctgaa tcacgatatg ttttatgact acgtaattta gtcataaagc gttctactaa
    54541 atcaactgcg atatcatcta cacggtcgtc attgttaccg tatttaggga agtcgccttc
    54601 gatttcaaag tctactacaa gaccttcttc gttacgaatt ggtttaactt gtgcatattt
    54661 aattgcagat aatgagtcag ctgctactga taaaccagcg atacctgttg ccattgtacg
    54721 tacaatttct gtatcatgta atgccatttc aatacgttca tagctgtatt tatcgtgcat
    54781 gtagtgaata acatttaatg agttaatgta aacacctgct agccaatcca tcatttgatc
    54841 aaatttcttg aatacttcgt catattctaa tacttcgctg ttaatacctt cgaagtttgg
    54901 accaacttgt gcaccagatt tttcatcttt accaccattg atagcgtaaa gtaatgtttt
    54961 agctaagttc gcacgtgcac cgaagaattg catttgttta ccaattgtca tcgctgatac
    55021 acaacatgcg ataccatagt catcgccata gctttcacgc ataatgtcat cattttcata
    55081 ttggatagaa cttgttttaa tactcatttt tgcacagtat gttttgaagt tgtcaggtaa
    55141 acgtactgac cataatactg ttaagtttgg ttctggtgct ggacctaagt tatctaatga
    55201 gtgtaagaaa cggaatgagt ttttcgtaac aagtggacgt ccgtcaatac ctacaccacc
    55261 gatagattca gttacccaag ttgggtctcc agagaataat tcattgtaat caggtgtacg
    55321 agcaaattta acaatacgta atttcatgat gaagtggtca ataatttctt gaacttcgct
    55381 ttcagtaata acgcctgctt taaggtcacg ttcagcatag atatctaaga atgttgatgt
    55441 acgacctaaa ctcattgctg caccgttttg ttctttaatt gcagcaaggt atgctaagta
    55501 taaccattga actgcttctt tgaagttttc tgctggacgg cttaaatcga aaccatattt
    55561 ttgtccaagt tcttttaatt cttttaatgc acgatattgt tctgataatt cttcacgtaa
    55621 acgaattaca tcttctgaca tttctgtaga catcgtgttg aagtcgtgca ttttttcttc
    55681 cattaagaaa tctacaccat ataaagctac acgacgatag tcaccgataa tacgtccacg
    55741 tccgtatgca tcaggtaaac cagtgattac acctgcttta cggcagttca acatttctct
    55801 agaatatgca tcgaatacac cttggttatg tgttttacga taatctgtaa agattttttc
    55861 agtttcttcg tctaattcgt aaccgtaagc ttcacaagct gctttcgcca tacgaatacc
    55921 accgaatggt tgcattgaac gtttgaatgg cttttcagtt tgtacaccta caattgtttc
    55981 taaatctttg tctaaataac cagcatcatg agatgtgatt gttgaagcta ctttcgtgtc
    56041 catatcccac atgccgccac gttcacgttc ttctttcgat aactgcatta cttgttccca
    56101 aagtttagaa gttgcttctg ttggtcctgc taaaaatgaa tcattacctt cataaagagt
    56161 gtagtttaat tggataaact ctcttacatc tacgtgtctg ttccatcttc catttttaaa
    56221 tccttgccaa gctgttgcat gatttttatt tgtttctaac atactaaacg cctccatctg
    56281 tataatgttg tgaatttgaa atgctatgtt aacgttttca tagtcattgt agcatgtttg
    56341 ttgtgatttt tttcacataa attatgtaca attttcatca aatgtatgtc aaaacataga
    56401 aactgtacta atttgtgtaa cagtaatatg ctaattgcat tctgttacac aacagttata
    56461 atgttcacta ttttcattgc tttaaaagtt aatttatgag tatatatttg tttataaaaa
    56521 atgattgttg ataagcgtta aatcaacact tagaaagatt tacttttata tatgaagaga
    56581 ctggattaaa tacttttatt gacgtaaaaa ttcacttttg aaccgttcaa tatcttgccg
    56641 atttttatat aacagctaca aataaaatat aacagtttga ttttacagcc tcggtaaatc
    56701 gtcttgacaa acaaaaattt tttgctatca caacatttgc aacgtcttaa caagtcatct
    56761 ataaacattt ctaaatattt aacattactt atgcgtcatt tattgctaaa attattgtat
    56821 taaaatatac atagaattga tgggatatca tgaaatcaaa aatttatatc ttgctattat
    56881 ttctcatttt tttatcagca tgcgctaata cgcgtcactc tgaatccgat aaaaatgtat
    56941 taacagttta ttctccgtat caatcaaact tgattcgtcc aattttaaat gattttgaaa
    57001 aacaagagca tgtcaaaatt gaaatcaaac atggatctac tcaagtactg ctttcaaact
    57061 tgcataatga agatctttcg gagcgtggtg atgtctttat gggtggtgtg ttgtcagaaa
    57121 caattgatca tccagaagat tttgttccct atcaagatac atctgtaaca cagcaattag
    57181 aggattatcg ctcgaacaat aaatatgtta ctagttttct attaatgcca acagttatag
    57241 tagttaattc agatttacaa ggagatatta cgattcgagg ttatcaagat ttattaaaac
    57301 ctatacttaa aggtaaaatt gcgtactcaa atccaaatac aacaacgaca ggctatcaac
    57361 atatgcgtgc tatttatagc atgcatcatc gagtaagtga tgtgcatcaa ttccaagacc
    57421 atgcgatgca actgtcaaag acgtctaaag tcattgaaga tgttgctaaa ggtaaatatt
    57481 acgcaggtct aagctacgaa caagatgcac gcacatggaa aaacaaaggt tatcctgtat
    57541 caatcgttta tcctattgaa ggaacaatgt taaatgtcga tggtattgct ttagttaaaa
    57601 atgcacaccc tcatcctaag cgtaaaaagt tagtgcaata tttaacaagc cgctcagtac
    57661 aacaacgatt agttgcagag ttcgatgcca agtcaattcg aaaggatgtt agtgaacaaa
    57721 gcgatcagtc tatcgaaaat cttaagaaca tacctttaat accgaaatct aaattaccgg
    57781 acattccaca tcataaattt ttggagatga ttcaatgacg gcatacaaac cttatagaca
    57841 tcaattgaga cgatcgttat ttgcgtctac tatttttcca gtatttttag tccttattat
    57901 tggactagta agcttctatg ccatctatat ttggatagag catcgtacga ttcatcaaca
    57961 tgttgatgaa agtcagtcat ctttacatca cactgaaaag cagattcaga catttattac
    58021 acagcataat aattcgtttc aagagctcga tttaacaaat catcatgatg ttaccgctac
    58081 aaaacgtgaa ttattaaaat taatacacca acagcccgca acactttatt atgaattatc
    58141 tggaccaaat cagtttataa ccaataatta tgaacattta aacactaaaa atatgtattt
    58201 attttcaacg catcagctta aattcaaaaa tagtacatat atgcttaaaa tttatatggc
    58261 taacacccca cgtttaattg aaattaagaa agatagccga caattcgcac ttatcgttga
    58321 tcaatatgac aatattttat acgccaatga tgaccgtttt actataggtg aaaagtatag
    58381 accacaacaa ttcggattta tgaatgaatc tgtaaaatta aaccatgctg accatcgtct
    58441 cattatttat aaagatatac atgaaaacat tgaagatggt atcacgttgt taattgttat
    58501 ggccgtagtt cttgttttac tagtaatatt tggtttcatt agcgcagata atatggctaa
    58561 acgacaaaca aaagatatcg aaacgattat tcaaaaaatt tactatgcca aaaatcgtca
    58621 tctaggtaca tatacgcctt taaaaaacaa cagtgaacta gaagaaatta ataattatat
    58681 ttacgattta tttgaatcaa atgagcaact gatccattct atcgagcata cagaacgtcg
    58741 cttgcgtgat attcagttaa aggaaataga acgccaattc caacctcatt tcctattcaa
    58801 tacgatgcaa acaatacaat atttaattac gttatctccg aaattagcac aaactgtggt
    58861 ccaacaatta tcgcaaatgt tacgttactc attacgtaca aactcacata cagtggaatt
    58921 aaacgaagag ttgaactaca ttgaacagta tgttgcgata caaaacatcc gttttgatga
    58981 catgattaag ctccatatcg aaagttctga agaagcgcgt caccagacaa ttggtaaaat
    59041 gatgcttcag ccactcatag aaaatgctat taaacatggt agagatactg agtcattgga
    59101 cattactata cgcctgacat tggcacgtca gaatttacat gttttagttt gcgacaatgg
    59161 tatcgggatg tcgtcatctc gcctgcaata tgtacgccaa tctcttaata atgatgtatt
    59221 tgatactaag catttgggat taaatcattt acacaataaa gcaatgattc aatatggttc
    59281 acatgcacga ctccatattt tttcaaagcg taatcaaggt acgttaattt gttataaaat
    59341 accactttca agggggaatg tagatgttta aggtagttat ttgtgatgat gaacgaatta
    59401 ttcgagaagg tttaaagcaa atcattcctt ggggagacta tcatttcaat acaatataca
    59461 ctgctaaaga tggtgttgaa gcattatcac taattcaaca acatcagcca gaattagtaa
    59521 ttactgatat tcgtatgcca cgtaaaaatg gcgtcgattt actcaatgat attgcgcatc
    59581 tagattgtaa tgtcatcata ttatcgagtt acgatgactt tgaatatatg aaagccggca
    59641 ttcaacatca tgttcttgat tatttattaa aaccagtaga ccatgcacaa ttagaagtta
    59701 ttttaggaag acttgtccgt accttattag agcaacaatc acagaacggc cgtagcttag
    59761 catcttgtca tgatgccttc caaccactat taaaagtaga atacgatgat tattatgtaa
    59821 atcagattgt tgatcaaatt aagcaatctt atcaaacgaa agtgactgtt tcagatttaa
    59881 ttcaacatat cgatgttagt gaatcgtatg cgatgcgaac atttaaagat catgttggta
    59941 ttacaattgt cgattattta aatcgctatc gtattttaca atctctgcaa ttgttagatc
    60001 gacattacaa acactatgaa attgcagaca aagtaggctt ttcagagtat aaaatgttta
    60061 gctatcattt taaaaaatat ttacaaatgt cgccaagtga ttattgtaag caagctaaat
    60121 agattagcaa ataactaatg attatggcgc ctacattttg ttctatgaaa aagcggactg
    60181 atagagaagt tttcactttt ctttcagtcc gctttttaga gagtttaaat ataaaacaat
    60241 actccctaca atatcgacac cgctatatgt ctttattgta aggagtaaat tcattgagtc
    60301 accctaagtc gggcaaataa ggatacttca taacagggaa ttatgatctg ccccgagaca
    60361 tagagatgat atatttgcaa gggtagaagc agtatctttc atctcttcac gcacatgccg
    60421 tcggggcagg attgccaact atattgcaat agattggcga tacttttaat ccgattgata
    60481 ttagattttt aaacttctaa ttttcttttc ttcatagaaa gcaacgattc ctaatagaat
    60541 catgcctagg aataatgcaa catagaagac gatgaaaaca tctgtccatc cacttaatgt
    60601 atatccaaag atgtttaaac cgttacgtgt tggatcagca atagccgcca aaccaacttt
    60661 cgccattgag tcaccgaata gatacgcgaa tgaacctgtc attccgtttg ctacactgat
    60721 ggcattttta ggaacaaaac cagtcaatga tacaccaatt aataattgcg gaccaaagat
    60781 taacgcacct aatgcaaaca atgaaatgtt aaccatcatt acacttgtag catttgtgta
    60841 gaataagaca acaaatgtaa tcataaacat acagccaata gctacaattg cacgacgacc
    60901 ttttaataag tctgatacgt agccccataa taaacttgca actaatgcac caatttcaaa
    60961 gtagaatatc gtattaactg catcgccttt actaaagtgt aaatgctctg acacatataa
    61021 cggtgcccag ttatcaatac cgattcgtac aatgtataca aagacgtttg aaacacatag
    61081 aatccatata acaggatttc ccaggatata ttttttaaag atctcccatt tcgtcatacc
    61141 ttgagaatca atattttctt tatcgaccgg ctcttcccaa atttcttcag cacgattcca
    61201 tcctaattct tctggatcat cttttccgat aaataatgtt gcgataccaa taagtaatgc
    61261 aatcaccgat gggaaaatga acatccctat aacatttcca tggaagaata cattagcacc
    61321 ccaaagtgca acaccacctg caatggcacc accgatatta tgtgatgtat tccaaaatcc
    61381 taagtatcgg ccacgtttcg ttcttggcgc ccatcttgaa atcgttgaat aacttgcagg
    61441 tccaccaact gattggaaca ccccgttaag tccccaaagt acaattaata atcccattac
    61501 agaaccaaag taacttaaaa caaatcccat aattaaaact gtaatcgcag ataagataag
    61561 taagaacgag ataatacgtt ttgtgttacg tccatcgaca aaatatccaa gtaatgtttt
    61621 ccctaaaccg tacgtgatac taaatgctaa tccgatataa ccaagttcta atgtagataa
    61681 tccaatttcc tcttttaaaa acggttgtgc cgccttaaag ttgtttcgaa ttaaatacat
    61741 agccatataa acaaagaaca ctacaaagaa agcttgcata aagtttctaa gccataattt
    61801 acgttgtacc gataatggaa tgcctttgtt cggaatctta tggatatcaa aaaagttcat
    61861 ctctgtcacc tcaatcattt tcgttaagcc aaatatatca cgtcggtgta agcgcttaat
    61921 atccttaaaa ttattaaatt atccaaaata ctgaacataa acacatactt agaaacattt
    61981 ttatgtacta aaattaataa atagttaata gtatttgaca agttttatct ataaaatact
    62041 ttatgttgtc aaaatcaacg tttatacata tgacataatg acggaggaca tcatgattct
    62101 atctatatta cttatctttt tctgtatcag acttgtcagc ttaaagatat ctattaatca
    62161 ctcaaaacaa ttaaaagcag acggtgcagt tgaatatggc gttaaaaatt cgaagttttt
    62221 agcaataaca cacgttttaa tttatgtatt ggctggtgta gaggcattta ttaataaaga
    62281 tacatttagc tttgcaaatg gtattggctt agttatatta atctttgctt atatcatgtt
    62341 atttatggtt attaaaactt taggtggtat ttggacatta aaattattca ttttacctaa
    62401 ccatcctatt attaaatctg gattatataa aattacaaaa cacccaaatt acttcttaaa
    62461 catcattcct gaattaatcg gtgtattatt attaacacac gcaacatata caactatttt
    62521 attagtaccg tatgcgtatt tcttatatgt acgtattaaa caagaagaga aattaatgaa
    62581 tatttaaaaa gatgaaagcc tgtcatcaca ttagtcgaca tcgacgtcca tctttaaagt
    62641 gcgttctgaa atattatatt cagaaacctt taaagtatgt cgtgtctatg accattgtga
    62701 caacaggctt tttttattat catatacctc actatcgaaa aggttatata ctcttttcaa
    62761 tggtgaggat tgttactgtg aatgggtatg accatcgcta aacacttata taaagtacac
    62821 cttctttaca aacaatgaca tgatttaagg tgtgaaattt ttggcaatgg cttggcgaca
    62881 tatgcattca ttcaacactg ccatcagtct tacttcagac aaacttcaga ctaacctcga
    62941 gttcgtatta tgcccaccac atgtctgctg gcttgtcgta aatattaaca gatttcaaag
    63001 tttgacaagc tttttggaaa ccttcttcta ctgacataat aggatcttca tgttcaatac
    63061 ttaatacata atcatatcca ttaataataa gttgacttat gatatctgcc catacatatg
    63121 gactatgtcc ataaccaact gtacggaatg tccatgctct tgtcgcaacg ttaccatatg
    63181 gttgcatatc agttagacca tacatattta cattttcttg attaatatac gtatctttag
    63241 catggaagtg atgaattgca tttgcttggc ctaatatgcg aatcgcagca attgggtcaa
    63301 taccttgcca ccataaatga ctaggatcta agttagcacc gatatattca tttgtagcct
    63361 cacgtaactt caacattgta tatggtgtat gcactaaaaa tcctgcatgc aactctatgg
    63421 caatttttac atcttgctct tttgcaaact cagctaaatc ttgccaatat ggtatcaact
    63481 tttcattcca ctgataatca taaatttcag agtaggctgt tggccaaggt gtaacaggcc
    63541 aattaggctt tttagcggta tcatctgacc ctgcaatgcc agaaaatgta ttaacaactg
    63601 gcacgtctaa tagatttgct aaacggattg ttttacgtaa cgtttcatcg gcttctttcg
    63661 cttctatcgg atctggagaa attggattgt tatgacaact gaaaccactt atttgtaagc
    63721 ctctgtctgt gattgacttc ataaatgctt gtcgcttgtc ttcattttct aacaactcat
    63781 ctaacttaca aaatttatct cctgggttac cacctgttcc aacttcaatc atatccaatc
    63841 cagattctgc gacataatct aacatatctt caaaattttt atcgtaaaat aatactgaaa
    63901 atacacctat tttcattgaa aagcactcct tctttttata ttgagaattt tgtatcatat
    63961 atgataatca ttaaagttgt atactcttat tatcaagatc actacgataa atcgcttcta
    64021 taagggcatt tacattgcgt gcttcttccg gtttcaccac aatctcttct atacctaaac
    64081 acgcattgac aaagttacgc gcctgtctct caccagcaat gtcttcgtta tgctcaacat
    64141 tagctttgct ttcaaaaata gttccaaagc ggggctcata tatttcaaat ggaaataaat
    64201 tgataccgcc atcttctcct gataaactaa cgtgtacctt atcttccttt atatttgcag
    64261 accacgaaca ttcaaactgc atgcttgctc gattggcaaa tgtcatataa ctagtaacat
    64321 gatcatcgac atcaaattta gtgtgatcaa atgttcccca atcattaatt tgattcggtt
    64381 gtttgctcaa ttgattatat gtttttccta gcacttcatg cggcaccata tctttaccta
    64441 atagccacaa agataagtct aacaagtggc aaccataatc gattaaacta ccgccacctt
    64501 gcaacgcttt attggtaaaa acgccccacc caggtacttt acgcctacgc atcgcttgta
    64561 cacgtgctac taatggttta ccaaccacac ctgcttcaat tgctttttta gcagtcatag
    64621 cgacatctgt gtgacgataa tgataagcga cagttaataa tttgtgattt ttattagccg
    64681 cttcaatcat gcgatcacac tcttccgtcg tcattgccat tggcttttcg cataagacat
    64741 ggacaccatg gttcaatgct tctatagaaa gatcagcatg gaatttattg ggtgtacaaa
    64801 tgaccaccgc atcaacaagt ttaaacagct cgctaggtgt ctcaactgcc tgaggtatat
    64861 taaagcgctt cgcaacatca atcatctgca ctgtattaat atcttgtact gcaactaatg
    64921 agactgtgtc tttgagtttc agcaatgctg gaatatgacg gtcttgtgca ataccaccaa
    64981 cacctatcac accaactttt aattttgtca tgatgtgcct ccttaccgta tgatgttatt
    65041 caaagtaaat tgctttgcct gattttgcag actgataaat cgcttcaaga atttttgtaa
    65101 ctaccattgc ttgttccggt ttcacaactg gttcagtatc atttacaact gcatcaatcc
    65161 aagcttttgc ttcttcttca gcttcatcca cttcattacc ttcataaaag tcgacgcctt
    65221 tgttttccaa ttcaacgtgt ttggtataaa gtgtgcccat gtcttcacca tgaatacgta
    65281 gaccatcttt catatcagca cctgctttcg ttcctgataa tgaacatttt gcctcatcca
    65341 cttctaaaga attaatcgcc caagcggatt ctaaaatgat cgtcgctcca ttcttcattt
    65401 taataaatcc aaacgcagaa tcttcaactg taaattcatc tggattccat gaaccccaag
    65461 cgtttgccgc atgatgctgt ttatttaatt tatggaatgt tgaacccatc actgattctg
    65521 gctcataatt atccatcatc cataacgtta aatctaaagc gtgtgtaccg atatcgatta
    65581 atggtcctcc accttgagct tcttcgtcta gaaagacacc ccatgttggt actgctcgac
    65641 gacgaatggc atgtgccttt ccgaagtaaa tgtctcctaa gtcgccacgt tgcgctgctt
    65701 gatgtaaaaa ttgactatct ggtctgaagc gattttgata acctattgtt aattttttac
    65761 ctgttgattt agctgtatct atcatttttt gagcttctgc tgtcgtttta gccattggtt
    65821 tttcacacat cacatgttta ccggcatgca accctgctac agtaatttca caatgcgagt
    65881 catttggcgt acaaacatgg ataacatcaa tcgtgtcatc ttttaacaat gctttgtaat
    65941 catcataaac ctttgcattg tcagttccgt atgcttctgc cgcactcgct gctttcgaaa
    66001 tgtctacgtc acaaaatgcg atcatttcaa cattttcaac tttttgtaaa cttggcatgt
    66061 gcttgccatt cgcaatacca ccacacccaa tgattccaac tttaatcgtc atcataacgt
    66121 cctcctttta atctttatcg tcattagtgg ttctttatca attctgcccc actcctaatt
    66181 tcaaactaac cttttgtcgc acctgttgtt aaacctgata ctaaatagcg ttgcaagaac
    66241 aagaatacga ttgctatagg tactgcaatc ataattgccc ctgctgcaaa cactgtgaaa
    66301 ttatttgcat acttatcatt aataaagttg aacaatccaa ctgctaatgt gaatttttca
    66361 ggacttctta atagtatttt aggtaatata aagtccataa atggccccat aaaattgaac
    66421 aaagcaacaa ctgctaaaat cggcttagct aatggaagca taatttgtaa gaaaatacgc
    66481 atatgccctg caccatcaat tttggcagat tcatcaagtt cttttggaat cgtatcgaag
    66541 taacctttca ctaaaaaggc attcatcggt attgatccac caatatatac cagtgttagt
    66601 ccaaataaag aatctaataa tccaattgta tttagcaaaa tatagattgc gaccattgcc
    66661 attaatacag ggaacatttg taaaatcaaa aatgtaatca gcccgtattt acgaccaaca
    66721 aagcgatatc tagaaaaagc atatgctgtt aacgtgacaa atatcacact aaacagtgca
    66781 tttgcagatg ctacgataag cgtattttta taccaagtca ggtattgact actgtcatcg
    66841 aatagtaaga atgcataatt tttaaatgtt gcattgtctg gtatcatttt ggcaccatac
    66901 aagttcgtac ctggattaag ggaaatgcca aatgtccaca gtagtggata taaaatgatg
    66961 acaaacatca tcgctataaa actgtaaata ccgattgctt ttaatatgtt tttcttcttt
    67021 gtcatcttat aaacctccct catctttaaa cgtacttgta cgtctgaatt gaataaatgc
    67081 gacaatagca acaataaatc caataattaa tgacacaact gcacccatgt taaagttgtt
    67141 aaactcaaat gtcagattat acacccaaga tatcaagata tctgtacttc cagcattctg
    67201 ccctgacact ggtggaccac ctttattaaa tagataaata agattaaaat tattgaaatt
    67261 acctgcatat tgcataatta acaatggcgc tgtggcgtaa atgacatgtg gaaatgtgat
    67321 atttctaaac ttttgccaac tagacgcacc atccatatct gctgcttcgt accaatctga
    67381 tgaaatactt tgcagtacac cagtgaacag tgcaaagaca aatgggaaac caagccatac
    67441 ttgaatgccg attaatgcca cttttgccca aaacggatca cttaaccatg ctggtgctac
    67501 acctaataaa ggttgcaaaa tatcattatt tatcgcacca aattcatcat taaataacgc
    67561 tacaaatatt aaaattgtca caaatgatgg tacagcccaa ggtaggatta acacagtacg
    67621 gataaatttc ttacctttga caacagggtg atttacaata attgccaaaa acagccctaa
    67681 tgcaatttga agtgtcgttg caacaagcgt ccatactaat gtccaagtaa taacactgaa
    67741 aaatgtttta cgccaaacgc caattgtgaa taacgttttg aagttatcta aaccgaccca
    67801 ttctaatgtg tgtctcggag gcgcgttgta taaattgtaa tttgtaaatg ctactccaaa
    67861 cataaatatt aatggaaata caactacaaa tatcaataag aatgtacctg gtgagattag
    67921 taagtatggg aaagtcttat cccatgttgc aaccatacgt gccttcggat cttttatttc
    67981 ctcattgcga ttaaatcgtt cagcattacg atatgcatct aaaatattaa tgacatatag
    68041 catgattgca aaagcaacga gtaagataga aataatacct tgtgcaagta agacacgaga
    68101 atcgtctaac ttaggtactg tccctaatgt gaacaatccc caaaaaccaa tatttaaaaa
    68161 gctataaaat acagaaataa aactgatgaa aaagataaaa aatatcgtcc ctttaatggg
    68221 tcttttatta taaaactgtc ccaaaccagg tataacagat aataatgctg ctaatttagg
    68281 gttacgtttc gtcataacta atctcctttc ttatcatttt gtgatggatg aagaatctta
    68341 atattttgcg ttatatcatt cgtcgcctca tctaacgctt gtttaggatt cttaccattt
    68401 gagataaata tgcttgcatt gcccatcggt tcccaaactt gtcgcatttc aggaatatta
    68461 ggcatcggtt cagcatgacg tgcttgcttt tcaaacactt ttaaatttgg attagatgat
    68521 ttcacgtcaa cacgtccagt aatttcgctc atttcatctg tatatttttg taatgtatct
    68581 ttactagtga tatacaacat taaatcttta gcccaatact tatgtttact atattcagat
    68641 aaataccaac cacgtacacc gagaaatggt ttcataggtt tgccaccatc tgtaggtaat
    68701 gttgttactc ctaaatcttt accaaacgtt tcttgatatt cattaatgtt ccacggtcca
    68761 gtgacaaatt gtcctacttt tccttcttta aaaagaccaa tcatgacatc atgtgttgct
    68821 gccttaggaa gatacccttt gtcgtaccat ttttgtaatc gttcagcatt tttgacgaca
    68881 tgttttgaat ttagtcctag ctgatgaata tcatattcac tgccattttt cttgaaaata
    68941 taatcatcat tgccgaataa aaacggataa ttaaaataga aatttttagc atcaaataac
    69001 ataccgtatt gtttcttttt actatcagtt agtttggcag cattagcttc aacttcttct
    69061 aacgtttgcg gtgcattttt cactaatttt ttattataga aaagtgcggt tgtttctacg
    69121 atagctggca atgctagttg cttattgtca taattcatcg ctttaagtgc ttgcttattg
    69181 aaacctttca actcatcttt tgataatttg atttcagcag ctaagccttg tagataggca
    69241 cttccagtat tatcatgtgc taagaaaaag atatctggac cttttcctac aggagcgtct
    69301 agcgaaatat tttctagttg atcattttga ccaatattta caagctttac tttgatgcca
    69361 gtttttttag tatattgatc cgtaattttt ttataaaacg ccatttgctt gtcgccatcc
    69421 acccacatcg taagttggtt aggcttgtct ttagaattat ctttattcaa tgctttatca
    69481 atatcttctt tcgaacgatt agggccacat gcagttacga ttaataacat taccacggct
    69541 aacgtgatac attttaaaat tttagacatg aatactcccc cttagacgat acgatttcct
    69601 gttttttcat caaaaaagtg acacttattc atatcaaatg ctagtgtaat cttgtcgttc
    69661 gccatcactt gtgttcttga atctaattta gaaatcaatt ccattccttg gaatgtgcta
    69721 tgtaccataa tttctgaacc taacagttcg gatacaacta cttcagattc aaattgtgtc
    69781 tctggagagg tttgaataaa tattggttct tcatgaatgt cttcagctcg aatacctaaa
    69841 ataatttcct tatctaagta gccagcagct tttaactttt caaatttttt attatgtaat
    69901 ttaaaatggt gtgttcctac cttcaatccg tccatttcaa ctgtagcatt caacatattc
    69961 attgctggtg agccgataaa ttgcgccaca aatatgcaat taggggcatc atatatttct
    70021 ctaggtgtgc cgacttgcat aatgtcgcca tctttcaaaa caacaattcg actagccatc
    70081 gtcaatgctt cagtttgatc atgtgtaaca taaattgtcg tagtattaag tcgcttatgt
    70141 aatttcaata tttctgtgcg catttgtact cgaagcttcg catcaagatt cgataatggt
    70201 tcatccatta aaaagacttt cgcatcccta acaatagctc tacctaaagc aacacgttga
    70261 cgctgtccac cagataacgc ttttggttta cgaccaagat actcagttaa tcctaatatt
    70321 tcagctgctt cattaacttt ttgttcaatc tcttttttat ttactttacg tagctttagc
    70381 ccaaatgcca tattttcaaa aacagtcata tgtggatata atgcatagtt ttgaaatacc
    70441 atcgcaatat ctctattctt tggttcaaca tcgttcatgc gttccccatc aatataaaaa
    70501 tctccagatg tgatagactc tagtccagca accattcgta atgttgttga tttaccacat
    70561 cccgatggtc caacaaatac aatgaattct ttgtcagtaa tatgtagatt gaaatctttc
    70621 actacagtat tgttgttatc atacgtcttt ttaatatgct ctaactttag ttctgccatg
    70681 ttatgcctcc catactttgt ttacagtttg attgtgcaat acactttgtg aaaacgtttg
    70741 cataaatact tacataaatc atatagtcac ttattattaa tgtcaatcat aaattgtaaa
    70801 cgtttacatt actgtcagaa ttaaactttt atacagaaaa ttgatatagc gcacaactat
    70861 ttttggtgtg gcaataatga ttttttacgt gcgatatttc actgccaatg ctaacaacct
    70921 tgtcttacat tttaagtaat atctaaatca aacaattatg ccttagcatt tcgattttca
    70981 ttgaaaaaag caatcattgt gtaagtatca tactcacaca atgattgctt aattttttag
    71041 actgcgggca ctcttctata gctacaaatc atataggcta cgttccccat caggtaactg
    71101 atcaataaac ggtttaggat cttctgcata tgcattacct acgccaccct tcattctttg
    71161 aaaatgtaaa tgtgcgcctg tcgtttgttt acctgtattg cctgaatatg caataatatc
    71221 acctgctttg actcgatcac ctactttgac attatatttg tctaagtgta gataccactg
    71281 gtgatattct ccattgtctt cggcaatctg taataccttg ccgcctaatt cattattaaa
    71341 gaaacgtgtt actttaccat tcgtcggcgc tttaattggt gtaccttttg gcaatgcaaa
    71401 atcaatgcca taatgcttac catcaaatgg tgaatgttga tatttaccaa aagtctcagt
    71461 aatccgactc cctctaaaaa agtcttccca ttttgagtgt ccttgtcctt tatgattttg
    71521 tgtcaattta tcggtatatt ggttaaacca tttttgaatg tcatctatat aaataatcgt
    71581 aaataatagt gaaagaaaaa tgataattgt tgccaaaata cgttttggtc gctttgtcat
    71641 agtggcatcc atccttcata tattttgggt attaagtata tattctaaat caactatttc
    71701 ataattaaat gcactcatac tttagtagta ctgccaaata tagatgaaga aaatgatggt
    71761 aatttgaata tttttattga tatcaaattt tatatctagt ataataatta tacttaagaa
    71821 aataacagaa ccagaggaga attttcaaat ggcaaaagta ttatatatta cagcacaccc
    71881 ttttaatgaa ctggtatcaa attctatggc ggctggtaaa gcatttatcg aaacatatca
    71941 acaacaacat cctgatgatg aagtgaaaca tattgattta tttgaaactt atattccagt
    72001 tattgacaaa gatgtattaa ctggttgggg aaaaatgagc aatggcgaaa cgttaactga
    72061 tgatgaacaa atgaaagttt caagattgag tgacatttta gaagaatttt taagcgcaga
    72121 taaatatgta tttgtaacgc cgatgtggaa cctttctttc ccacctgtag tcaaagcata
    72181 tattgatgcc atttcaattg caggtaaaac ttttaaatat tctgctgaag gacctcaagg
    72241 tttgttaact gacaaaaaag tattacacat tcaatcacgt ggtggatatt atactgaagg
    72301 acctgctgct gattttgaaa tgggtgaccg ttatttaaga acaattatga cattcttagg
    72361 tgtgccatca tatgaaacaa tcattattga aggacacaat gctgaacctc ataagactga
    72421 agaaattaaa gcaactagta ttaataatgc tgaaaaatta gcaacaactt tttaaatttt
    72481 taattacact gtgtgactcc tcaaacgtca cacagttttt aattgtatgc atttcctact
    72541 tttttataaa tacctattat ttccacacat ttaaagtttg atattcactt taatactgat
    72601 gtaaatattt ttaaaatata ttattatagt gttaattaag tattttaaga aaaggtgtga
    72661 atgtatgaaa gcacataaaa ttttctggtt aaacttagca gcaattatta ttatttcaat
    72721 tgtagtcagt ggcggtatgt ttttggcaat gaagtgggaa caaattcatt tgaaagatgg
    72781 tcttaaaaaa gtactaagta catatcctat taaaaactta gaaacgcttt atgaaattga
    72841 tggtcacgat aatccccatt atgaaaataa tgatcaagac acatggtaca tagaatcctc
    72901 ttattcagtt gttggatcag atgagctttt taaagaagac cgtatgttgt taaaggtaga
    72961 taagaacaca cataaaataa ctggtgaata tgacacaact acaaacgata gaaaaaatgc
    73021 tactgactcg acatacaaaa gttatccagt aaaagtagtt aataataaaa tcgttttcac
    73081 aaaagacgta aaagatccca cgctgaaaca aaaaatcgaa aacaatcaat ttttgattca
    73141 aaatggtgat ttaacaagca ttttaaatag caatgatttg aaagtcacac atgatcctac
    73201 cactgattat tataatttat ctggtaagtt gtcgaatgat aatccaaacg ttaaacaatt
    73261 aaaacgtaga tataatattc ccagaaatgc atcaacaaag gtggaattaa agggaatgag
    73321 tgatttaaaa ggcaataatc atcaagatca gaaactttat ttttattttt caagtcctgg
    73381 aaaaaaccaa attatataca cagaaagcct tacttataat aaattaagtg aacattaata
    73441 cttatgatat aattatagaa ataaccaaat catttattat cgtttaacat actaaaatca
    73501 cacattataa aaacgcctca catcattcat ttaattgtac cgaatcacat caagttagat
    73561 tttagactaa ctattgtggt gtacatcaaa aacgaatttg tggggcgttt tatattttac
    73621 aaaggcgact agcgtttctt ataacaactt caacattact acactcaagc atcactctaa
    73681 agtttgaaat cgaacccttt cgttcaacaa aaatcaaaat ccacttcaaa ctatatatca
    73741 aatacataaa ttatcttgtg atactatctc gatcatatct atagtatgca tttgtgtttg
    73801 ctttcactga atgatacgtt tcatcagtta agtataaact gtcatccttt aaggtaactt
    73861 gataaccttt cttccgtgcc aaccaggcaa tatctatata attttttccg gcgatttcat
    73921 aacttcttaa atcttcaata tgcacactaa cttcagggaa aatgattcta ataacacttt
    73981 catcaaccca atatttgtca tacatccacc gcacttgttc agcatataat ggcaactgca
    74041 tatcattgaa atatactcga tgggtgtcat tatcgtatat tttcggacta ggtaatggtt
    74101 cttttctaat tgataataca tcgccaccta tcactgtgcc ttctctcgta tcatcagcac
    74161 ctcccgacgc gtcacgtgta ttcaagtcaa cctgtagtcc atgtacatct ccaatatagg
    74221 catctggttt atgttccatt gcatgtccac gtgcaatcaa tgctaatatt gtagattgtg
    74281 aaaattgagg ctcccattca atgcgattag gatggctact ataaactcta ggttcatcta
    74341 tagcctgctg aatatccatg ccaaacacta atacattgat taatgtttgc gcaacactag
    74401 caatgatact tatggcacca ggtgcaccta ctgttaatat cggcttcccg tgatacatca
    74461 caatcgttgg agccatgtta cttagtggtc gtttatatgg tgcaatttca ttaataccac
    74521 catctactac atcaaagcca tccattgtcg tattcaataa cacaccgtag cctggaatcg
    74581 taatacctga accataaatc ataccaattg atgtcgtaaa tgaagcaata ttaccttcct
    74641 tatcaatcac acaaaaatga gttgtttcgg tatgattttc ttcaacatct gtatgactaa
    74701 tgcaatcaga cacaacacca tgctctatat caatatttgc tttattgcta tcaatgagcg
    74761 tactgcgtgc ttttaaataa tcgtcatcaa ttaatgactg tacaggcacc tcatgaaaat
    74821 tatcatccgc caagtattgc gcacgatcac tatatgctaa atgcatcgct tgtatcaaat
    74881 gatgcaagta atcaacagat cttggaccca tagatggtaa atcgacatgt tctaataact
    74941 tcaatatttg aattaccgtg ataccgccag aactagatgg tcccattgaa taaatgtcat
    75001 agtctttaaa tgttgcactg attggcgctt taatctgaat gtcatatttg gctagatcct
    75061 ctaaagtgat tgtcccacca catgctttga caacattgac taattgtttc gcaatgtcac
    75121 ctttataaaa tgcattaaac ccttgttctc ttaatatttg aaatgtctta cctaattcgg
    75181 gttgtacaat ccaatcacct tcacgccaat attgattttc atgcgtaaat acttgcgccg
    75241 tttcgtgata ctttgtcaat cgtgcgtgtt gctggcgcga atatttttca gtagcccaat
    75301 tggctgaatg accttcaatg gctagttcaa ttgcaggatt aattaaatct tccaatgaca
    75361 atttagcata acgcttgtga atataatcaa acagctttgg aattgctggc acagcgacag
    75421 ttttaccatg tgtagtcata tcaaaaaatg atttatattc gcctgaatca tctagataaa
    75481 attgtttgtc tacatgtgca ggggctgtct cacgcgcatc aaacgcagtt atactgccag
    75541 tactttgctc ataatataac aagtacccgc caccaccaat acctgatgca aatggttcta
    75601 ccacattcaa tgccagttga attgcaatca ctgcatccat ggcgttgcca ccttgatcta
    75661 atacatcctt accaatttta gccgcaagag gatgtgatac ggaaattaac ccttctttag
    75721 atgtttttgt ctgtttgtca tttaagttaa tgaccattct atatcctcct actttctgtt
    75781 aaatatttaa aacattattg attaatggct ttttctactt tttctaaatc ttgacgttgc
    75841 tcgttaccag tatcgacaag tggtgtaatc ggtgatgcaa ttttaaattt atcgccacga
    75901 taaaacttaa taaattgatc ctgatttatc gcattaacta ctgcttgtct caagtttgga
    75961 tgcgtcttaa atataccttt tttaatattt agcattaaaa agactgattt gcgtccattt
    76021 ttgcgaataa tgcttaaatt tttatccgac ttaattaaat caaaatgttt ttgattcaca
    76081 tctgccaaca tatcaattga atgatttcta agttctgaca atgcattatt cgggtcacca
    76141 ttaaacttca atgtaatatt tttaatttta gctggtccat aactaccttt ttctgtttcg
    76201 ttgaatcctg gattacgttg aaacgttgct tgatatgcat ttttctgtgt cataatgtat
    76261 gcaccacttg cataaagcgc attttttcca tctgaatttg caggaattgt actgctatcc
    76321 ccatatcctt ttggatattc ttgatttact tgattaacaa attttttaga taaaatgcct
    76381 gccgaagagt gtgttaagta atttacctct cgaggcatcg attgatctgt cgtaatttta
    76441 acaatttgat aaataccgtc tttattattt actttttgac catctgtcgt taacgatttg
    76501 acgttatacg ctttaatcaa cttatcatag attgatttat cgtccttgtc tttctcttta
    76561 cgcaactgat cgatgtcctc atcttttaat atcttgatgt catttatatg tttgtgcata
    76621 ttgtaagtat tattgttagg cacagacttt ttatcacgtg ctctatctaa agaaaactta
    76681 acatcttcag ccgatacacg ctctccagta ttacgtgctt gtccattgac cactttcgca
    76741 aaataatcat catctcttaa caagaaataa aacgctttat tgtccttatt cacagcataa
    76801 tcacgactta acgaaccttt cgttgttaag tgatcatttt catctaataa taataacctt
    76861 gtgtacatat tcatattaat tgaatatact gacggcgcaa ttgaacgtat tggatccaat
    76921 gtaggaattt caccatcttg ttgtgtcatc acaagtggcc gcgtatctcg ttctctacta
    76981 ttgttgtaat caaattgttg ccatattaat gcacgtgaat ttggcaatcc aacactattt
    77041 ttatctaaca ctttattgtc atatactaaa ttcttttttg atccatataa tggcgccata
    77101 taccctttat caaatacaac ttcatcttca atttgcttat atgtttgttt aacatctgct
    77161 tcattttgag tagaagcttt atttaacaac tggtctacat gtttatcttt caataaacta
    77221 tttgatcctg tagaactaaa taatgccgtc atagcatagt tcgggtcacc aaaaactgtc
    77281 atccagtcat cgatttggat atcataattg ccggcttgac gttgtgtacg atagctacca
    77341 taatctggtt ggatattcat cttcacgtta aatcctgcat tttccaattg atctttgacg
    77401 atattcatat cattttcata acttgcttgt cctaggaaat gtattgttgg tcgctcgcct
    77461 ttcacttcaa ctttcgatga cttttgagcc acttctgatt tcgtagggac accacaacca
    77521 cttaatacca acgctaaaac tataattgcg atactaatga ttttcttcac atctatccct
    77581 acctttttaa tgaattcttg gatctagtgc atcacgcact gcatcaccta taaaattaaa
    77641 tgctaaaacg acgaacataa tacaaacacc aggtacaata gctaaattac tgtgcgtttc
    77701 caagtagtta ctaccggtac gtaaaatgtt gccccattca gctacatcag gtgcaacacc
    77761 aagtcctagg aaacttaaac tacttgttgt taatacaacc acacctatat ttaatgaaaa
    77821 acgtacaatc ataggcgcaa tcgcattcgg taaaatataa cgccatatga tattccaagt
    77881 gttttcacca gtgatacgcg ctgcatctac atattccatg cgtttaattt ctaaaacact
    77941 ggcacgcatt gtccgtgcaa atgatggtat attaccgata cttaaagcaa taattaaatt
    78001 gggaatactt gctccaaatg atgcaataat tgccaccgct aacaataatg atggaattgc
    78061 aaacactaca tctaaaattc gcattattaa attatcaata tgattaaaat aacctgcgat
    78121 agtgcctagt aacacaccaa aaataactgc aataactact gaaataattg aaattgaaaa
    78181 tgtcagcttc gttccgacaa ctacgcgtgt aaataagtct ctaccgaaat catcagtacc
    78241 aaacggatag gctagactcg gtccatgtaa cagtgcattg aactgatttt tagtagccaa
    78301 tgtcgtatca aatgtaaatt gtgacacaat tgataatgtc agcatgtaga ctaaaataag
    78361 taacccgata atcgcaatac gatgtctagt agtttttcgt ataaacgatt cccagccgtt
    78421 ataactatgt atttgcgatg tacgttcata acgtctaata cttacaaaca ttaataatgt
    78481 aaatacgttg cctgttaatg tcatcaataa taacaacact tcgacaatac gtcgccatag
    78541 gtcatgatgc ttccatgttt gttccgttgt taagatgata attaaaatga tagttaaaac
    78601 gattagcaat gtttcagcaa tatagaacgt atcggccaca taacctttaa aaagatttaa
    78661 tgcactcgtt aatataacta aaatataagt tgcaatagca taacttgcga atagttttaa
    78721 ggaagctatc tttgttgtaa gttttaccat atgcctcact tcctttcgtt aatttcacta
    78781 cgtaattttg gatcgattaa agcataaaat atatcaataa ttaagtttgc taaagatatt
    78841 acaattgata tatatacgac cccacccatg actgctggga tatcaggtat tagttgtttt
    78901 tggacgatat aacgaccgat accattaatg ttaaatactt gttccgtcac tgctgaaccg
    78961 cctagtaact ctgccactag aagaccaact agcgttacaa ttggaataat ggcatttttc
    79021 aaaatatgtt taataactac ttgtgtcgtc gataatcctt ttgcataagc agttaaaaca
    79081 taatcactgc gcattacttc aagtacagaa gaccttgtca tacgcgtgat agaagcagca
    79141 atacttgttc caatgacaag tacaggtaaa atcaacgata ttggatgttc tggcatataa
    79201 gatggtggca aaatatccaa tttcaatgag aacgctaaaa tgaataatag cccttgccag
    79261 aaacttggaa tagataaacc aattaatgca attatcatta acgtgatatc aagccaacta
    79321 tttcgcttca tcgcactgat aattccaatt ggtatcgcaa taattaatgc cacaattagc
    79381 gctaatactg cgacaattat tgtaattgga attctttcgc caactgcttt agtcacaacc
    79441 tcattccctt tgtaagtcgt acctaagtca aaagtaaaaa cacccttgat ggtatcccac
    79501 aattgaataa aataaggttc gttaagatga tgtaatacat tgaattgatg tatctgtgcc
    79561 tttgttgcat tttgtcccag tatgctataa gccgcatcaa gcggtgaaaa atacagaatg
    79621 gtaaacacac tgacaataac accaatgatg acaatcacag ccatgacaat tcgctcaaaa
    79681 atatatctaa ctaatggctg taaataaata gtcaataaga tgaacatcgg taaggccaat
    79741 atcactttga taatgatgaa cttatgaaat aatacatttt caaagtatgt tgaaaaatgt
    79801 gcttgttcaa tattctttga attcgtatta gaactttgtg ccttgaatat ttttaatgct
    79861 tctttatgta tttgtgtgga taacttttgc tgcgataaat atttatattt ttgatgtaac
    79921 gcctgttcga tttctgaaat ttcagaatta ttagcgtaaa aatttttcct cttagcagaa
    79981 aagaaaaact ttatcactgc atataaaaat attggcaagc ttaataccga taatacaaac
    80041 ttgtaaaatg ccttgtgata caacgactta aaagattcta aataagtaat tatgataatc
    80101 actccttgta aaataatctt gagtagatta ctatgatata caaaagtata gaataaattt
    80161 acacatttgt gaatagggag gcacaacatc atgtcaaatt tattagaagt caacagtctg
    80221 aatgtacaat tcaattatga tgaaactaca gttcaagcgg taaaaaacgt ctctttcgaa
    80281 ttacgaaaaa aacatatcct aggtattgtt ggtgaatcag gatcaggaaa aagtattact
    80341 gctaaatcta ttttagggct actaccagat tatccagatc acacattaac aggagaaatt
    80401 atttttaatg ggcaatcgtt aactaattta tcaacttcag cgttacaaca aattcgaggc
    80461 aaggatattt caatgatttt tcaagatcca ctctcttcgt tgaatccaag attaacgatt
    80521 ggcaaacaaa ttacagaagt actatttcaa cataaacgtg tatctaaatc tgaagcaaag
    80581 tcgatgacaa tagacatttt agaaaaagta ggtataaaac atgcaactcg acaatttgat
    80641 gcttatccac atgaactttc tggtggtatg cgtcaacgtg tcatgatagc aatggcattg
    80701 attttaaagc cacaaatttt aatcgcagat gaaccaacaa cggcattaga tgccagtaca
    80761 caaaatcaat tactgcagtt aatgaagtcc ctttatgagt acacagaaac atctattatt
    80821 tttatcactc acgatttagg cgctgtgtat caattttgcg acgatgtgat tgtaatgaaa
    80881 gatggaagtg tcgttgaaag tggcacggtt gaaagtattt ttaaatcgcc acaacatacc
    80941 tatacgaaac gcttaataga tgcgattcca gatattcatc aaacgcgtcc gccaagaccg
    81001 ttaaacaatg atattttatt aaaattcgat cgcgtgagcg tggattacaa gttaccaagt
    81061 ggcagcctat accgagcagt taatgatatt aacttggcta ttagaaaagg cgaaacatta
    81121 ggcattgtcg gtgagtcagg gtcagggaaa tcgacattag ctaagacggt cgtcggtcta
    81181 aaggaagtgt cagaaggctt tatttggtat aacgaattac cattaagttt atttaaagat
    81241 gatgaattga aagctttacg acaagagata caaatgattt tccaagatcc attcgcatct
    81301 attaatccaa gatttaaagt cattgatgtg attaaacgac cactaatcat tcacgggaaa
    81361 gtcaaagata atgatgatat tattgaaatt atcgtatcgt tgttagaaaa agttggccta
    81421 gatcaaagtt tcttatatcg ctatccacac gaattatctg gtgggcaacg ccagcgtgta
    81481 agtatcgcga gagcacttgc tgtagaatct aaagtgattg tttgcgacga ggcagtgtcc
    81541 gctttagacg tttcaattca aaaagatatc atcgagttat taaaacaatt acagttagac
    81601 ttcggcatta cttatttatt catcacacat gacatgggtg ttatcaatga aatatgtgat
    81661 cgcgttgcag ttatgaaaaa tggcgaaatc gttgaactta ataacacaga agatattatc
    81721 aaacatccgc agtcagacta tgcaaagcaa cttatttcag aagtagcagt tattgctaaa
    81781 taaaagtcat gcgttgtgta actttatcac tgtatggtct ggaataaatc aggcaatctc
    81841 tgatgtgtta tgttagatga ctttgtcata ctaactatat tgtgttaagt tagggctcgg
    81901 caccatatca agttttaggt gctttgccat gatttaagag tcacccccat actttgggca
    81961 ttttgacgcc agaataaatc ccccgctact atgtgaagtg cgggggatta tttatatttt
    82021 attagaatat tcagattttt gagtgtgtca acttagctta gtcaatgtat atttaacatc
    82081 acttactctt tttctttcat aattaacaca ttcaaataaa ctttgatcaa aaaacacaaa
    82141 gttaaaagta ccatcttgca atatgctctc atacattatc ccgtcatatt taaggcttcg
    82201 aatataatca gctaaatatt gaaatggcaa ataatctatt ccttgttcat cgcttggatt
    82261 tgttattcct ttatgaatct tttttaatgt ttggtaattt acaaaatact ttctaaatcc
    82321 atcatcgcca gctttgattg cattactagt taaattagtt aaattcgcaa ttttcaattt
    82381 ctcttttgta acgttttttt gtaacttaac cttacctata taaataatgt cattatgctt
    82441 aggtttaact tcttctatac tgacctgttc ttttgtacta aggtataata cgcttatcca
    82501 tttagaattc aatcttcctg ccgttgcaaa tccctttggt ggtgacatta gttcactttt
    82561 ctctgtaatg aacttaacta ttctagatct atataatggt tcaaatcttt ctctaaattc
    82621 ctcaatacta tagtaattag tagtgatatc gagaaagaac gctaaattct ctaaattaat
    82681 catattatta tgaaatctat tgttatactt caagctctca caaaatccat cccagtcatt
    82741 atttgctaca attagatttt catttgtata ttttttatcg tttatgattt tagcgcctac
    82801 taaatcttcc aacactcgtc tatctaaatt ttcatcatct ttaaaaagtt catttaaaat
    82861 acaacttatt tgagcttcct caactttaaa tatactccag tcgtctttta atgctatttc
    82921 aatcttttta ccttcttttg ggctaaaagt atctggtaaa tttatactaa tatcatataa
    82981 ttctaatgct ggtcttaaat aatctctaat aagttctaat ttatctttgt ccttagtcgt
    83041 atcaaatatt ttaacaccaa gatgattgtt atcaatatca caattgtcaa ttttgctatt
    83101 atcatttgca atgatttcta cgatttcagt attattaaaa catttttcac atattttcat
    83161 tttgagactc caagtatcta ttcataattt ctagatgatg catgatagat aaccttttaa
    83221 ttaaacctaa gcctggatac ttattatttt catttaattc ttcaaattgt ccaagcgcat
    83281 aagatctatt tttaatatct aagttttttg accatgttac taatttatct acagcctcaa
    83341 aaaacttttt acctggattt gatctatcat tattagaatc agagacaaaa tgcttaactc
    83401 ttagctcatt agcctcatca aaatagacaa tatgtatcgc aatagctaat ggcgaaaagc
    83461 caccgtctac atattctcca cctataacag aatagtctga aaatgctacg tatccatctt
    83521 ccttataata aaggtgatcg tcgctataaa actcgtcatc attatctaaa taatcaacat
    83581 tacgacttag tttattaaaa ggatccataa tgatgccttt gtttggaata ttacgcaatt
    83641 tacgtttaat gtgtctatca tctggtataa aaaccatttc aagtttattt ttatctccaa
    83701 acatttccca gtcatctaca cttgttaaaa tagctaaact attacttgaa aattgctgtt
    83761 tcaacctatc attgccttca tcagaaggac ccaagtaagc tttttgaata acacttttgt
    83821 tttttgttat tatttcagtt aaatgttcaa cagtttcgtt actaatctct tcttcagtta
    83881 actttgaatt tactactaaa tttatagaga atgctttttc accacagtat tgcaaagtat
    83941 ttttaaatgt ggttgtatat ttaattggtt caattatagg ttgaatacaa tcaccaatca
    84001 aacctttctc taacaattct ttaattgcaa atagttcatt ttgtttccca cgcaaataag
    84061 gataatacat attaatcctc cttaagaaaa tgatatagtt tatttttatc tttctttgtc
    84121 atttttgcga aatataacaa gaacttaatt tcagtcggag ctgctaaaaa ttcatctttg
    84181 tattctttca tgttgcctct ttttttcaac tcagaaatca tattgttatg cagtttcgtc
    84241 attggtattt ctttaaacac gtcaaataac acatcatact ctgtgaaatc attataagtt
    84301 ggtacatcca tatgattttg tgcaataact ctttttcttt cttcttttcg taaaaagttg
    84361 tacatcgctt tcgtgtttaa gagactattg ttttctttag gtttttgaac ttcactcagt
    84421 gtatttctag ttgttaacac taaaattcca actgttgtat ctttgtatct agccataact
    84481 ttattcagat gtttgttatt tgtaatgact acgacataat taaacacttc ataataatca
    84541 ttaatttgat tatctaatct atccaactta tctaattctg ttttaatctc atagacaacg
    84601 cctttgccgt ttaacaatat aaaatcagca atacttttcc ctatgggcat ctcagaaagt
    84661 gcagtagttg tattaacaga atgtcgtcct agaaggagtt tattaagcat tgtgtttttg
    84721 taaaaatatt cgttacgata agacttttta agatagttat ataaagactt cattttctgt
    84781 attacattga tatttttagg tccctgtata taaaaatcat atgcctcatc aacaacatca
    84841 cttttatttt tgattgcaat ttgatgtaat atcttttgac taaaaacacg attaatcata
    84901 tttctattat ccatagctac gcacctcctt caacatacat ttaatactta tcctgttaat
    84961 attataaact attttaaatg cctatagaca ttatttctat acacatacga tgataaaatt
    85021 ttattgaaac caagtgatga ttgcaaaata aatgagcctt ttctaatgaa ataattatgc
    85081 cccctacact aatctagcga gggggctgaa tcattacaca ccgtattttt cagttgtttc
    85141 tgccacgaaa gattcaatgg cttttcttgc tttacgtttt tcttttaatg gcaaatcacc
    85201 aatcattttt ttaaggtgat gtgggtttac aacaccacta tactgatagt catttgaaat
    85261 tgtttttagg gcttgttcat cgatagatct ctctccagca aatcctttga actccgcttc
    85321 ttttttaata ctttcgaaat taacatattc ttgatcgata tcatcatcct tatttaaaga
    85381 aggtacaaca ttgtcgatga attctctaat tagatctcgt tttaacctca atgtcggatc
    85441 atctgcatga tctaaaatgc gtctaatttg ttcttggtta cgacgttgtt ccgctttgtc
    85501 ttcaagatca atttgtctca atatattcat aatataattc acattaatcg tatcattacg
    85561 catcatttct atttcgaaat caatatcatt taaaatggat actttatttt tctcagccgt
    85621 cgctcttttt acttgatcgt acacagctaa atatttactt ttatagtctt cattctcttg
    85681 ttcatccatt ccaatttcat caattgtaaa ctcaaactcg tcaaatgctt ttaaacgtaa
    85741 tattatttta gctaataaac gataagcttc aacaaagcgc tttagctctt cttcatcttg
    85801 aatgtcatca accatgtgtg gtgtcggcac aatcatttta agctcacgat aagcgtccat
    85861 aaattctttt ttatactctt cataactacg cattaaaatt gtatccgtat catttgtttg
    85921 tgagaatact ctcagtgcat cgtctgtctc ttttttcaag tcacgatagt ttacaatttt
    85981 accaaatggc tttgattctt tttcaaccct atttgtacgt gaatacgctt gaattaaatc
    86041 atgatacatt aaattcttat caacatataa agtgttcagt actttactat caaaaccagt
    86101 taagaacata ttaacaacga ttaagatatc aattttacta tctttaacgc cctttttaac
    86161 gttttttgaa atatgattaa aatactcatt agttgtgtct gttgaaaaat tcgtctcgaa
    86221 ctttttatta taatcgctaa tcattatctc taatttttca cgtgaatgat atggcacttc
    86281 accatcacga tcatcttcat taggtttaaa cgtaaatata ccagctaccg ttaatggttg
    86341 ttccaacttt ttgttaagtc gcttaaatgt ctcataatat ttaataagcg cgtgaatact
    86401 ttggactgta aatatacttg aatattgacg attacgtgta tatttatcat gattattgat
    86461 gatatgtcgt gttactaatt ccacacgttt atccgctaac catacttctt ccgtatcaat
    86521 tgcttcaacc atgctgttat cttctgcttt taaagcttta tttttaaaag tattaatata
    86581 gtcaactgag aaaccaagta cattaccatc atgaatggca tctctaatta aatacgtatg
    86641 taagcatcta ccgaaaatat ctgcagttgt tctaccatct tgactactat tttctggaaa
    86701 acgtggcgta ccagtgaacc caaagtattg ggcatttttg aaatgttgtt taactagacg
    86761 atgcatgtca ccaaattgac tgcgatgaca ctcatcaata ataaatacaa ctttattcgt
    86821 tttatactgt tctaataaat gggcattacc ttgaatcgct ttagccattt tttgaatcgt
    86881 cgttacaata agtggcaaac ttttatcatt tagttggcgt accagttgcg aggtattaaa
    86941 agttttgtct acagcaccct tagcaaattt attaaattcc tcttctgttt gactatccaa
    87001 gtctttgcgg tcaaccaaaa agataacttt cttaatgtca tcttgctgtg ataaaatctg
    87061 actcgcttta aaagaagtca acgtcttacc acttccagtt gtatgccaaa tatatccatt
    87121 attccctgtc tcagtcgctt gttgaattag tgcttctacc gcatacactt gatacgggcg
    87181 cattgccatc agtattctat ctgtttcatt aataatcata tagcgcgata tcatcttagc
    87241 taattgacaa ggtctcataa atgactcagc aaacgattgt aatgtattga ttcggttatt
    87301 ctgtttatca ctccaataaa acatgtgact cttcaatagt tcgctatcat tattagaaaa
    87361 gtatcgcgtt tcaacaccat tactaatgat aaacatttgt atgtagcgga ataagcctgt
    87421 gtaattttgt ttacggtaac gttttacttg gttaaacgcc tcattaatat caatgcctcg
    87481 acgtttcaat tcaacttgga caaggggtag tccattgatt aatatcgtta catcataacg
    87541 tgctttatat gtatcctcga cagatacttg attcgtcact tgaaacttat ttttacacca
    87601 acttttcgta tctaaaaacg acaaataaat ctcagactca tcatcacgtc taagtggtaa
    87661 tttatcacgt aaaatacggg cactctcgaa aatacttttc ccatcaatca tcgttaacag
    87721 acgttgaaat tctttatctg ttaagggatt gccttctaat ttgtccgcat gacgctcatt
    87781 taaaatcgtt ctaaaattat caagcaattg cttattatca cgtatcgtta ctctttcgta
    87841 acccaattgt tcaagttgat tcatcatttc attttctaat gcgtattcac tttggtatgc
    87901 cattcatatc cccttccata cactttctat tgctctaaat atatcataaa ctttaatgaa
    87961 aaatgtttgt tttttatctt caaacgtaaa tttattctaa ttttattgtc ttatctttta
    88021 atatttgtct ttgaggtaag tcgtatacta aaaacaccaa cacacactat cctttatatt
    88081 tttatacttc tatgccagag ttcaactttt gaatatattg tgtcctcaat tgtttgttct
    88141 ctgtatatat tttattgaat atgattgatt gaaaaacaaa agtgaaaatg tacatcacaa
    88201 ttggaataaa agcattataa atgccattat caaaatagga taaagaaaaa ataaataaag
    88261 tgaacactat cggcattgta aaacgacata aaataataga ccaattattt ataaaaagcc
    88321 aacttcttat taagtttttt ctattcagcg taatgatatg gaatattttg tcgtttttat
    88381 tttgataaaa actttcaact ttttcatagt gtccatatat ggtttgattt aggttaatta
    88441 ttttgtagtt tgatccaggt tcgtaaaggt cattattgcc aactttaaaa caatctttaa
    88501 ttaatgtact ttctttgttt acaacaaacc tatagggatg tatgtaatca caattttcac
    88561 acattttata taattgaaat ctattaacaa tcgctaaata atttctgtaa gttgaaatag
    88621 ctataaataa gattaatcca taacttatgc ctattaatga aaaccatatt gtattaataa
    88681 attcactatg aggtctttct agcagtttaa tatatatttt ataattcaaa aatcctaaaa
    88741 gaaaatacat tggtaacact gtgccaatca taataattgc cctatcgaat attctatatt
    88801 tattttcagt attaatgatt tttgaatacc aactttttaa ctcaggaaat attacagacg
    88861 tgaaaattgt tagcgataaa gtaaccatta tcttattgtt ttcttttaca aaattaatca
    88921 tctcgttaag ttccaaatta attccccctt aataacagca tttaatttcc atctatgaaa
    88981 aaagcaaagc tcaaatctga actttgcttt aatttgtcac gcctttatca ttttcaaaat
    89041 agcctctatg ccagttttac aaacttgtag caacaatttt tcatcaagca actgaatcac
    89101 atcaaaaact tcaattgttt acgttgcaac taactttata ttagaacgcg cacaatatct
    89161 aatgtttaaa atctatcgtc gcaagatgct tcctgtaatt atcaagtgcc attttcgatt
    89221 gggttataca atctagaatc gcatgataat ttaatgctac aaatcgatag tacaatatat
    89281 ctaccgtgaa taactgtgca aatagtgacg ttgtagccgc catacgcatt tcattttcat
    89341 cagttctgcc ataaatcaat gcatagtctg caatttgagc cactggatta ttagctgtac
    89401 tagatatagt tatgatggga atactgtaat gtgtggccac ctgtgcaatt gactgcaatt
    89461 cactatgact accttgattc gtcacaaaaa tcatgcaatc tctatcatca tgcgtcgcaa
    89521 atgttgacac aagtaaatgc gtttcatgta ataacctgac atttaagcca atacgagata
    89581 acttttgaaa aagatcacca atagtcaaac tcgatgcgcc aaatccaaat aaaaatattg
    89641 tcctggcatt tttcaacaca tcacaaattg catcaatttg cgcatccata atattagtag
    89701 ctacaaatcg catcgtattc gttgctctag caatcatttt atttttcaaa gtttctacag
    89761 gttcattttc aatcaattcc aaatgtggat tggttgcaat atcttcgggt aagtatcgag
    89821 atatcgcaat ctttagctct tgaaaacctt gatgtgtcat tttccgacta aatctaacaa
    89881 ttgatgctgt actaacattc gtaacatctg ccaaatcatt cacagtcata tcaatgattt
    89941 tatgtggatt ctttaaaatg taatcagcga ttatcttttc tgtcttcgta aaatcactca
    90001 actgcttatc aatgcgatat aaaatatttg tcatcattaa tcacccaaca aatctgtctg
    90061 tcgcatcgcc tttgtcgttc caaataaata tgtacaaacg aatccaccag catacgcagc
    90121 aagtaaccct gcaatataac ctaaatacat attatctgag attaatggta atagtgacac
    90181 accacttggg cctattgctt tggcaccaat atgtccaatt ccacctatta cagcaccacc
    90241 aataccaccg ccaatacaag cagttaagaa aggtcgacct aatggcaaag tcacaccata
    90301 gattaatggt tctccaatac ctaggaaacc aactggcaat gcacctttta aagtattacg
    90361 taatgttgtg ttgcgtttac atcttaccca aagtgctaat gcggcaccta cttgtccagc
    90421 accagccatc gctgctattg gcaataagta agtagcacca gattggttaa tcatttctat
    90481 atgaattggc gtaaaaatat gatgaagccc taacataact aacggtagga agcttgcacc
    90541 aatgataaat ccactaaata cgccaccaat actaataatt ccgttaacta ctgaaactaa
    90601 actgtctgaa acaaaacctg ctaatggcat aaagataaag atagttaata gtcctacgat
    90661 caacaatgca atagtcggcg ttacaataat atcaatcgca tttggcacaa ttttatgcaa
    90721 tctcttttcg acaatactta aaatccaaac ggcaaaaata acgccaataa ttccaccttg
    90781 tccaggttgc aatggttctc cagtgaagac attcattaaa atatttttac cagcaatacc
    90841 cgttaataac gttgtaccac caatcacgcc accaagtcct ggtgtcgcac caaattcttt
    90901 agccgcatta ataccagtga aaatagctaa gtatgctaac ataccgtctt taatgacatt
    90961 aaatactgtt ataagttgcg taatccaagc acctgaaata taacctgcca ccattaagtt
    91021 actcagtact gctgcaatac caccaattaa tccagctcca ataaatgcag gaatcaacgg
    91081 tataaagata ttggcaattg atttcaatac tttattcgac ttaccattct tttgttttgc
    91141 tttatgtgct tctttattcg cctttgcttt atcagctgca tatgatttat agtccatttt
    91201 ttcactatca ttgtgatggt gtggtattgg gtcacctagt ttaacaccac ttaattccgc
    91261 catatgatta gccactttat tgactgtacc aggtccaacc acaacttgaa tgcgttcatc
    91321 gtgtataaca cccatgacac catcaatatg ccttagttct tgatcatcta ctttattttc
    91381 atctaatact ttaatacgca cacgtgtcat acagttcatg acactatcta tattatccat
    91441 accacctact gcagcaataa ttcgttctgc aagttgttgt tctttggtca tttaaatccc
    91501 tcctaaggtt gtctatctct gattgctcgt ttaacaatgt caccattgtt tagtaaccgt
    91561 cttgttgctt cttccttaga aatgccacac atacccataa ctgtcgcaac tttcacatca
    91621 tgctcagata cctgatataa cgccattgct tcatcatatg tgatagcaca tatttcttga
    91681 ataatacgca ctgaacggtc gatcagtttt tgattggttg ctttaacatc aatcatgagg
    91741 ttatcgtaaa cttttccgac accaaccatt gtgatggttg aaatcatatt taaaattaat
    91801 ttttgtgctg taccagactt taaacgcgtt gaaccagtta atacttctgg accaacttta
    91861 acttctactg gatactgcgc aatttcactt ataactgcat gttcattgca tgaaatagat
    91921 actgttgtag caccgattgt gttagcaaat gttaaaccgc ctataacata tggcgttttg
    91981 ccactcgcgg caattcctat aacgacatct tttgatgtta aatctatatt tttcaaatct
    92041 tcttccgcta attttttgtg atcttccgca ccttctacag ccatcgtcat agcatgttgt
    92101 ccaccagcaa taatacctat aatttcatga gggtcagtat tgaatgtagg tacacactcc
    92161 gctgcatcta agacacccaa tcttccactt gtacctgcac cgatatagat caatcgtcca
    92221 ccctttttat actgtgcaat tgttttttta attacttttg tcaattgtgg tattgccttt
    92281 cgaactgcta acgggacttg ctgatcttct ttattcatcg taattaaagc ctcttccaca
    92341 gtcatttcat caagatgcat cgtcgcttca ttacgcgctt cggtcgtact attttccatc
    92401 acttcttaca ctccctagtt ttttgaaaat caaatgtatc attcggctcg atacaactta
    92461 acagtggtaa gtcttcttta ataatttgtg caacaacatt cacattgtca tgtgcactaa
    92521 gcgtttgtct cacaatttgc atttcacctt gataacgtcc gttattcaaa ttatcaacgg
    92581 ttactgaacc aatgcgtcgt tgcgtcgtaa actgtggttg aatcgaatgt ggacatattt
    92641 gtcttgacgt ttccgaacga atgacatttt ccggattatc cgggcgtact ttatgacaca
    92701 tatcgaaaag gtaagtcacc gtcgtatcaa acacttcttc aatacataac gtgaaatgcc
    92761 tatgcttgca aaaatctata agttgttttg cctgcctcat ttcaatcaat gagtctccaa
    92821 ctaacacttc agatacacca gtttcttgta gtaatttagc tgcaacgaca ggatgactat
    92881 gtctcgttgc ttcaattgtt ggcaagcctt tatgcaaagg acctcgcaaa ccactcccta
    92941 caataaaacc atatatttgt gcctttggat taaattgata aatgagttca tttttcttat
    93001 tgaccaagtc aacagataat cccgtatctg gtcttggata atagttatga caaaatgaaa
    93061 gtaatgtaaa atcattcaat tgttgatgta agcttgttaa caattcccgg gaaataatac
    93121 ttgcattcaa acagcacttt aaaccctgtg ccattatcgc ttcgattgcc tcaattgatg
    93181 tactatgatc gatacgaatc ataaattgtg catcatattg ccgaagatgc tcataaaaag
    93241 atggtgttaa aatagatgga ttagcatcta tgaggtaagt cacttgttca tgttttaata
    93301 aattgagtag ttttgtgaaa taatgatatt ttgtctcgtc atcttcttct ggtatttgta
    93361 cagatgtaaa aatcatttgg taaccttgtt taatcattcg cttaatatac gcttcatcta
    93421 aaggttgtcc taaatacact gaaaagcctg tcaaagtagc cctccttaac aatataatta
    93481 ttaggaaaat atagttgagt tgtgtaatcg cttacatttt actataagag aaaacacatt
    93541 acaatattaa tcagttaaag cctgttcatt gtaataatct tacatatttt tgtcacaagt
    93601 taattattac accatcaaag attatccttt cttttaagtg ctgataatag ctgctattgc
    93661 tgaattgtta caacaacttt tatacatttt attcaagatt atcttatatt atgttttaat
    93721 aataatctgt gaacaattaa gagatttgaa attgaattta ataattgtat tgaaaacgca
    93781 tacttcacca tgctaaaata ggagtcgcaa acaaataaga ttcaataaga tgtgatggta
    93841 agctagataa actaacgtat ccgttttata tactacttag tcaattgctt cttttacatt
    93901 aattacatac accaacgtgt tactaagtaa gattaggcat gagttaaatt aagctgtgat
    93961 ggttaccaac acagtctatt tgctcgtgcc ttttttattg aatcttaaat aataaataca
    94021 actttggagg ttggacaagt gaggaagaaa cttttcggtc aattgcaacg tattggtaaa
    94081 gcgctaatgt tacctgttgc gattttacca gcagctggtc tgttattagc tatcggtaca
    94141 gctatgcaag gtgaatcatt acaacactac ttgccgttta tacaaaatgg tggcgtacaa
    94201 actgtcgcta aattaatgac gggtgctggt ggtatcattt ttgataactt gcctatgatt
    94261 ttcgcattag gtgtcgcaat cggattagct ggcggtgatg gtgtagcagc tatcgcagca
    94321 ttcgtcggtt acataatcat gaacaaaaca atgggtgact ttttacaagt aacacctaag
    94381 aacattggtg atccagcgag tggttacgct agcattttag gtatcccaac attacaaaca
    94441 ggtgtgttcg gcggtattat aatcggggcc ctggcagctt ggtgttataa caagttctat
    94501 aacattaact taccatctta tttaggtttc ttcgctggta agcgtttcgt acctattatg
    94561 atggctacaa catcatttat tttagcattc ccaatggcat taatttggcc aacgattcaa
    94621 acaggattaa atgcattcag tacaggatta ttagactcaa atactggtgt tgccgtattc
    94681 ttatttggtt tcatcaagcg tttattaatt ccattcggtc tacatcacat tttccacgca
    94741 ccgttctggt tcgagtttgg ttcatggaaa aatgcagctg gtgaaattat tcacggtgac
    94801 caacgtatct ttatcgaaca aattcgtgaa ggcgcacatt tgacagctgg taaattcatg
    94861 caaggtgaat tccctgttat gatgttcggt ttacctgcag cagctttagc aatttatcac
    94921 acagctaaac ctgaaaacaa gaaagtagta gcaggtttaa tgggttctgc tgctttaaca
    94981 tcattcttaa ctggtattac agaaccttta gaattctcat tcttatttgt agcaccatta
    95041 ttattcttta ttcacgcagt acttgatggt ttatcattct taacattgta cttattagat
    95101 cttcatctag gttatacatt ctcaggtggt ttcatcgact acttcttact cggtatacta
    95161 cctaataaga cacaatggtg gttagttatt cctgtaggtc ttgtatacgc agttatttac
    95221 tacttcgtat tccgattctt aattgtaaaa ttaaaataca aaacaccagg tcgtgaagat
    95281 aaacaatcac aagcggctac tgcttcagca actgaattac catatgcagt attagaagct
    95341 atgggtggca aagcaaacat taaacattta gacgcttgta tcacacgtct acgtgttgaa
    95401 gtcaacgata aatctaaagt tgatgttcct ggtttgaaag atttaggtgc atccggtgta
    95461 ttagaagtcg gtaataatat gcaagcaatt tttggtccaa aatctgacca aatcaaacat
    95521 gaaatgcaac agattatgaa tggtcaagta gtagaaaatc ctactactat ggaagacgat
    95581 aaagacgaaa ctgttgttgt tgcagaagat aaatctgcaa caagcgaatt gagccatatc
    95641 gtgcatgcac cattaactgg tgaagtaaca ccattatcag aagtgcctga tcaagtgttc
    95701 agcgaaaaaa tgatgggtga cggtatcgct atcaaacctt cacaaggtga agttcgtgca
    95761 ccattcaacg gtaaagtaca aatgattttc ccaacaaaac atgcaattgg tcttgtatca
    95821 gatagtggtt tagaactatt aatccacatc ggtttagaca ctgttaaatt aaacggagaa
    95881 ggctttactt tacatgttga ggaaggtcaa gaagttaaac aaggtgattt attaatcaac
    95941 tttgatttag actacatccg caatcatgca aagagtgata ttacgcctat tatcgtgaca
    96001 caaggaaaca ttacaaacct tgattttaaa caaggtgaac atggcaacat ttcatttggc
    96061 aatcaattat ttgaagctaa ataatgctta ctataaacag gtgcgtatac cttcataagg
    96121 tgacgcgcct gttttttctt tgctattgta ttttgcggta tcattgatag ttcgctctcc
    96181 ccttaaattt tgaattttaa gatcatcaat taaagccccc cttcatactc atttcctaaa
    96241 aaatattaat tgttcactat cgttagcgtt ttcacaacaa agtcaactta cttgacctta
    96301 cactgtattc gaggctatca ttttaagtgt aaatatagag aaaaggtggt ttttttatga
    96361 aacaacgcat tggagcttac ttaattgacg ctattcatcg agcaggcgtc gataaaattt
    96421 ttggtgttcc tggtgatttt aatctcgctt ttctagacga tattatcagc aatcccaatg
    96481 tagattgggt aggaaataca aatgaattaa acgcaagtta cgcagcggac ggttatgccc
    96541 gtcttaatgg actcgctgca ttagttacta catttggtgt tggcgaatta agtgccgtca
    96601 acggtatcgc aggttcatat gctgaacgca tacctgtcat tgcgattaca ggtgcgccga
    96661 cacgtgctgt tgaacaagcc ggtaaatatg tacatcactc acttggtgaa ggtacatttg
    96721 acgactaccg aaaaatgttt gcacatataa ccgttgcaca aggttatatc acacctgaaa
    96781 atgcaacaac cgaaatacca cgtttaatta atacagcaat cgccgaaaga cgcccagttc
    96841 atttacattt accaatcgat gtcgcaatct ctgaaattga gataccgaca ccatttgaag
    96901 tgacggcaac taaagatacg gatgcatcaa catatataga gttattagca actaaactgc
    96961 atcaagcgaa gcagcctatc atcattactg gacatgaaat taacagtttt cacctccatc
    97021 aagaattaga agattttgta aatcaaacac agataccagt agcacaactt tcattaggaa
    97081 aaggtgcttt taatgaggaa aatccatatt atatgggtat ttacgatggg aaaattgccg
    97141 aagataaaat acgagattat gtggacaaca gcgatttaat tttaaatatt ggagccaaat
    97201 taacagattc agcaacagca ggattttcat accaattcaa tatcgatgat gtcgttatgt
    97261 taaatcatca taatatcaaa attgacgatt ttacaaatga cgaaatatct ctaccatcgt
    97321 tgttaaaaca gttatccaat atttcatata cgaataacgc atcgttccct gcttatcatc
    97381 gtccaacatc acccgattat actgttggca cagaaccatt aacacaacaa acttatttta
    97441 aaatgatgca aaatttctta aaaccaaatg atgtcattat tgctgatcaa ggtacatcat
    97501 tctttggtgc ttatgattta gcattataca aaaacaatac ttttataggg caaccgttat
    97561 ggggttctat cggctataca ttacctgcaa cattaggttc acaattagca gacaaagatc
    97621 gtcgtaactt attattaatt ggtgatggct cattgcaact aactgttcaa gctatttcaa
    97681 ctatgattag acagcatatt aaaccggtat tatttgtgat taataatgac ggctatacgg
    97741 tagaacgact tattcacggc atgtatgaac cttataatga aattcacatg tgggattata
    97801 aagctttacc agctgtattt ggtggtaaaa atgttgaaat tcatgacgtt gaatcatcaa
    97861 aagatttaca agacacgttt aatgcaatta atggtcatcc cgatgtgatg cattttgtcg
    97921 aagtcaaaat gtctgtcgaa gacgcaccga agaaactgat cgatatcgct aaagcttttt
    97981 cacaacaaaa taaataattt catcgtatac agggtataag tttaagcgaa tactttatta
    98041 aacgaaaagg actctgatat aagatgatta attttaataa aaccgcttta gtgttaatcg
    98101 acctgcaaga aggtatactt aagatggatt atgcgccaca tacagctgaa aatgtcgttc
    98161 aaaacgctaa taaattaata gatgttttta gaaaaaacaa tggctttatc gcttttgttc
    98221 gcgtgaattt ctatgatggt aaagatgtat tgcaaccaaa tgcaatgatc tcattaccac
    98281 caaaagaagg cgacgactac agtcgtttcc atcatttatt agacaagaga gatgacgatt
    98341 ttgtcataga caaacgacat tttagtgcat ttgtaggaac agatttggac ttacaattgc
    98401 gacgtcgagg aattgatacg attgttcttg gtggtgtcgc aacgcatatt ggcgtagata
    98461 cgacagcgcg agatgcctat caattaaact acaatcagtt ttttgttaca gatatgatga
    98521 gtgcacaaaa cgaaacgcta catcaatttc caatagataa tgtattccca ttgatgggac
    98581 aaacaataac tacaaacgac tttctaaata tattgaacta aacatatact tccccccttc
    98641 gatcatgttg agggggatct ttatttcaca aagtattaat acgtcgggtt gtctaacctt
    98701 ctatatttaa catattctat atctgttaaa tcgttcttaa cttacgcccc tactacataa
    98761 gaaacagtat ttattccgga attttcaaaa aatttagtat ttattgcaaa attatgtatc
    98821 actttatgtt taatttttga tattatctta attaagtaga tttttataag ttctaaaaag
    98881 gagaacaaat acatatatga agaagaaact aacatttaaa gaaaacatgt ttataggttc
    98941 tatgttattt ggtttattct ttggtgccgg caatcttatc ttcccaatac acttgggtca
    99001 agctgctggt tctaacgttt ttatcgctaa cttaggattt ttaattacag caattggctt
    99061 accatttcta ggtatcattg ctattggcat ttcaaagaca tctggtttat ttgaaattgc
    99121 atcgcgtgtt aataaaacat atgcttacat tttcacgatt gccttatatc tagttatcgg
    99181 accatttttc gccttaccta gactggcaac gacatcattt gaaattgcat tttcgccatt
    99241 tttatcacca aagcaaatca ctttatattt atttattttt agcttcgtct tctttgtgat
    99301 tgcatggttt tttgcgagaa agccatcaag aattttagaa tatatcggta aatttttaaa
    99361 tccggtattc ttagtattat tagcaattat tttattattt gcttttatcc atccattagg
    99421 tggcatatct gatgcaccta ttagtaaaca atatcaatca catgccttat ttaacggctt
    99481 tttagatgga tacaatacct tagatgcgct agcgtcattg gcatttggta tcatcattgt
    99541 tgcaacgatt aaaaagttag gtatcgaaaa tccaactgat atcgctaaag aaacaattaa
    99601 gtctggtact atcagtatca ttatgatggg gatcatttat accctactag caatcatggg
    99661 tacattaagt attggtcatt tcaaacttag tgaaaatggt ggtattgcct tagcgcaaat
    99721 tacgcaatac tacttaggta actacggtat tgtcctgttg tcacttatcg ttatggttgc
    99781 ttgtttaaaa acagccatcg gtttgattac ggcattttca gaaacattcg aacacctttt
    99841 ccctaaaatg aattacctag cgattgcaac agttgtaagc tttatttcgt tcttattcgc
    99901 gaatgttggt ttaactaaga ttattatgta ctcagtccca gtgttaatgt tcttatatcc
    99961 attagcaatt gccttgattg tactaacatt atttagtagc aaattccatc attcaaaaat
   100021 tatttatcaa tgtaccattt tctttacaat gattgctgca ttagtagatg gattaaaagc
   100081 tagtccagag ttcatttcaa gcacatcatt ctcacaaact ttgattaatt tcagccaaaa
   100141 atatttacca ttatcagaca ttggtatggg ctgggttgtt ctcagtttga ttggtttcat
   100201 tatcggcttc attattttta aaattaagca tcgtaaaatt ccacaagcat aatactatgc
   100261 cacagtcata tgttaaacat atgcttgtgg cattttttat tcatactaca ttaaactgca
   100321 atcgtataca tacatatcaa tgattatcca caaaaaatat tagtactttc attttacaaa
   100381 tcacattaat acaaacacaa ccttatcttt atattattaa atttacattt gacacttata
   100441 ttgaacaact gtaatatatt aatattaatt ctttaaattg tataaatata aaggagggag
   100501 accgatgaat tcaatcattg aattaactga ttattatagc tctaataatt atgcaccact
   100561 taagcttgtc atttctaaag gtaaaggtgt caaagtttgg gatactgatg gcaaacaata
   100621 tatagattgc atctcaggtt tttcagttgc aaaccaaggc cattgtcatc caacaattgt
   100681 taaagcgatg actgaacaag cttcaaagtt gtctatcatt tcacgtgtcc tttatagtga
   100741 caatctcggg aaatgggaag aaaaaatttg tcatcttgct aagaaagaca aagtactccc
   100801 ccttaactct ggtactgaag ctgttgaagc agccattaaa attgctagaa aatggggctc
   100861 tgaagttaaa ggcattactg acggacaagt tgaaatcatc gctatgaata acaattttca
   100921 cggtcgtaca cttggctcat tatcactatc taaccacgac gcatataaag caggatttca
   100981 ccccctactt caaggcacta caacagtaga ttttggagac attgaacaat taacacaagc
   101041 tatttcaccg aatacagcag caattatttt ggaaccaatt caaggtgaag gtggcgttaa
   101101 tataccaccg aaaggatata ttcaagctgt gcgtcaacta tgtgataaac atcaaatatt
   101161 attgattgca gatgaaattc aagttggtct tggtagaact gggaaatggt ttgctatgga
   101221 atgggagcaa gtcgttccag acatttatat tttaggtaag gcattgggtg gcggcttata
   101281 ccctgtatct gctgtacttg caaataatga tgtcatgcgt gttctaacac caggtacaca
   101341 tggttcaaca tttggtggta accctttagc cattgcaata tcgacggcag cgcttgatgt
   101401 acttaaagat gaacaactgg ttgaacgatc agaacgctta ggttcatttt tattaaaagc
   101461 gttgctacaa cttaaacatc ctagtattaa agaaattaga ggtcgtggtt tatttatagg
   101521 catagagctt aacacagatg ctgcaccttt tgtggatcaa ctgattcaac gtggaatctt
   101581 atgcaaagac acgcatcgta ctatcattcg attgtctcca cctctagtca ttgatagaga
   101641 ggaaatcaat caaattgttg cagcttttca agacgttttt aaaaattaac aattaatcat
   101701 ttatatatga cataggaggg attcatgatg attaaagtag gtatcgttgg cggtagcggt
   101761 tatggcgcaa ttgaattaat tcgattatta caaacacatc ctcatataac gattgcacac
   101821 atctactcac attcaaaagt agatgaaccg ttgaaattaa catttccaca tttacaacat
   101881 attatgcaac atttcgaagc acttacagtg gacaataatg actgtgatgt aattttcttt
   101941 gcgacaccag cacccgtaag taaaacatgt atccctccct tagtagaaaa aggtattcat
   102001 gttatcgatt tatctggcgc atttagaatt aagaatcgtg aaatatatga agcatattac
   102061 aaagaaactg ctgcagcaca agatgatttg aatcatgcta tttacagcat ttcagaatgg
   102121 caatcgtttg ataacaatgg aacgaagctc atttctaatc ctggctgttt ccctacagca
   102181 acattattag cattacatcc acttattagc gaaaaaatag tagatttgtc atctattatt
   102241 attgatgcta agaccggcgt gtcaggtgct ggtcgttcat tatcacaacg tgttcatttt
   102301 tcagaaatga atgaaaatct aagcgcttat gcaatcggaa accataaaca caaaccggaa
   102361 atcgagcaat atttatctat cgttgcgggt caagatgtat cagtcatatt tacaccacat
   102421 ctcgtaccaa tgacacgagg tattttatca acaatttatg tcaaattatc atctgaatat
   102481 acaactgaat cattacataa attaatgacc tcttattatg ctaatcagcc atttgtcaga
   102541 attagagata ttgggacttt tccaaccaca aaagaagtac tcggtagtaa ctactgcgat
   102601 atcggtatct atgtagatga aacaacgcaa acagcaattt tagtatcagt gattgataac
   102661 cttgtcaaag gggcaagtgg tcaagccatt caaaacttaa atatattata taattttgaa
   102721 gttacgactg gcctaaaaca atcaccagtt tatccataag gggtgttaga atgaaacatc
   102781 aagaaacgac atcacaacaa tataactttt caattattaa acatggcgat attagtacac
   102841 ctcaaggctt cacggctggt ggtatgcaca tcggtttacg cgctaacaaa aaagactttg
   102901 gctggattta ctcatcgtct ttggcaagtg cagctgccgt atatacttta aatcagttta
   102961 aagctgcacc acttattgtc actgaagaca ctttacaaaa gtctaaagga aaattacaag
   103021 cacttgttgt taattcagct aatgcaaatt cttgtaccgg tcaacaaggc atagatgatg
   103081 cacgacaaac acaaacatgg gttgctcaac aacttcaaat accatctgag catgttgctg
   103141 ttgcttcaac tggggttatt ggtgaatatt tgcctatgga taaaattaag aatgggaccg
   103201 atcatattaa ggatactaag tacacaacgc caggtgcgtt taacgaggca attttaacaa
   103261 ctgatacatg tacaaaacat atcgctgtat cactaaaaat cgatggtaaa accgttacaa
   103321 ttggtggtag cgccaaaggt tcaggtatga ttcacccaaa tatggctacc atgcttgctt
   103381 ttataacaac cgatgcagcg attgaatcga atacacttca tcaattatta aaatcttcga
   103441 ctgaccatac atttaatatg attactgttg atggcgatac aagtacaaat gacatggtat
   103501 tagtcatggc aaatcaccaa gttgaacacc aaatacttaa tcaagaccat ccacaatggg
   103561 aaacatttgt tgatgcattc aattttgtct gtacattttt agctaaagct atagctagag
   103621 atggcgaagg cgcaacaaag ttaatcagcg tcaatgtgtc aggtgctaag tcaatatcag
   103681 atgcaagaaa aatcggtaaa actatcgtaa gttcaaatct agtaaaatca gctatttttg
   103741 gcgaagatgc caattttggt cgaatcatta cagctattgg ctatagcgga tgtgaaattg
   103801 atcctaactg cacatatgtt caactgaacc aaatacctgt cgttgataaa ggtatggctg
   103861 tactatttga tgagcaagct atgtcgaata cattaactca tgaacatgtc acaattgacg
   103921 ttcagcttgg tttaggtaac gctacagcga ctgcatacgg ttgtgattta tcctatgatt
   103981 atgtgcgtat taacgcatca tatcgaacat aaggtggtgt tggttagatg aaatttattg
   104041 tcattaaaat tggtggcagt acacttagtg acatgcatcc atcaattatt aacaatatta
   104101 agcatttacg atcaaacaac atctacccta ttatcgttca tggcggtggc ccttttatta
   104161 atgatgcatt atcaaaccag caaatcgagc cacactttgt taatggccta agagtgactg
   104221 ataaagcaac catgacgatt actaaacgca cgctcattgc agacgttaac acggcattag
   104281 tagctcaatt taaccagcac caatgttctg caataggctt atgtggtgta gatgcacagc
   104341 tgtttgaaat tacatctttt gatcaacaat atggatatgt cggagttccg accgctttaa
   104401 ataaggatgc tttacagtat atatgtgata aatttgtacc tatcattaat tcgattggtt
   104461 tcaataacca tgatggagaa ttttacaata ttaatgctga cacgcttgcc tattttattg
   104521 catcatcatt aaaagcacct atttatgtat taagtaatat tgcaggtgta ctcatcaatg
   104581 atgttgttat acctcatcta ccattaggtg atattaatca gtatattgag catggtgata
   104641 tttatggagg tatgattccc aaagtgcttg atgctaaaaa tgcgattgaa aatggctgtc
   104701 ctaaagttat cattgcatca ggaaacaagc caaatattat cgaatctatt tacaataatg
   104761 attttgttgg cacaacaatc cttaattcat aaccatgaaa ttaaggacta acaagttttg
   104821 acacgcgatg attccagttc gtttatccat tgcgctgaaa catttattta ccgttcatct
   104881 cgtcaataat tccgaataca gtatgataca atatgagatg taaaaaacta ataacctttt
   104941 acaaatttgt ttatcaaaat attttaagtt ttgcaaagct tttcattgtg attattttca
   105001 caaaatacta taatgaggat agtaaataga gaggagtcct taagttgacg aaacgacaaa
   105061 tgggtatatt catttatgct ggaattatcg gtggcttgtt atctggaatt gtaaaattag
   105121 gttgggaggt catgtttcca cctcgcacac cagaacgtaa tgcaacaaac ccacctcaag
   105181 agttattgca acaattagga tttagtagtg agtttacgca tcaaacatat acattttcaa
   105241 atatggaatt gccttgggta agctttattg tccactttag tttttctatc gtcattgcaa
   105301 ttatttactg catattagtt aaaaaatacg cttacttagc gatgggacaa ggtgctgtat
   105361 ttggtattgc tatttgggta ttattccacc ttatcattat gccaatcatg catactgtac
   105421 ctgctgtgtg ggatcaacca ttccaagagc atctgtcaga attctttggc catatcgtct
   105481 ggatgatgac aattgaatta gtgcgacaac attttgtcta tcgctataaa ttaaattaat
   105541 acactgacta acattaacgt gagttttaaa tcatcgtttg agtatgatga ttgatgctca
   105601 cgttatttta ttaactgaca tgatatgatt ccagccaact tacgtgagca ttaaagtctc
   105661 aaatgcgtcg taacaaacta ttattttcgg taatttcaat attgctcagt atattttcac
   105721 cttatcactt actttaatct cgtcatgatt ttgaatgatg ccatcgtgta ttcacctttc
   105781 atttttccaa taaaaaaaca tctaacagta aacatttagg cagtatagtt taaaatcact
   105841 gcgcaatgat actgtcagac gtcatattaa ctactcaata actgaaatac agacactttt
   105901 ttataacccc agggtgcctg tcctaagaaa catacctgta ccataaactg atcaaaaata
   105961 aattgtttga acttcacttc acgtgattga taaaagtgtg attgtgtcat atcataaatg
   106021 tccaatcctt tgattaaacc ttcaccaatc aattttgtaa aactttcttt ttgtgtccat
   106081 atttgataaa aatcatttaa actacatatt tgatgtgctt cgtttgtaga gaaacacgtc
   106141 actaacgtac gccagtctaa acgttgtgat atcttttcga tatctatacc aactggttct
   106201 ttatcgacaa cacacacgat ataaggataa ctatatgata agctcacata gatgggctgt
   106261 ccatcacgat tgtgttgaac aatatctgcc ttacctcgtg gcgaaatgtg ataatgccat
   106321 tcatgtggta ataaacctgt gtcatgttga attccatatt gcactaaaat atctcccaat
   106381 ctgtgcatga gtttatcttg attgtatcta tagttgactg tacgtggttt tttatatgac
   106441 caacgacttt gtgatattaa ttcttcaata cttttcaagt tactctgtaa ttgcattaca
   106501 aatactgtca taactttccc tacttactta ttgaatattg ttttgatata ttgcgcccaa
   106561 tgatgcagcc aattgttagt tatcgttggc catttttcac tgatgtgatt cattattttt
   106621 aatgttaatg ttgtatctat cattgctagt tgttgttcac ggtcaacact agttaatcca
   106681 atcgtttcgt acatgtcttg tttctgtaaa atttcattaa atgattcatc gctgacgagt
   106741 tcaatttctt tgcgcttaac gcattctaac aaagatttca ccggcatttt attaggtgat
   106801 agcacatggt aaatgatttg tggtgtgttg acctgtgcta atgcgacaat ttgtcttgca
   106861 gtcgtatcca caaaagaaaa atctacaggc atttcagcca ggctaacccc gatacaatcc
   106921 agttgtaaca aatcattcat taccattgaa aaacggttag tctttatatt tctcatatgc
   106981 catcttccat tgtaaggact cgtcaaatta ccaacacgta caatccgacc atctaagcca
   107041 ttatttacag cttctaatac ttttaattca ctataaaatt tactccgtgt atatggtgat
   107101 gttagtagtt gtcctttata gacatccgct tctgaaaatg tcacatcttc tgtgtctata
   107161 tcaaaataag ttcccacact tatcgtagac acatatatta accttgcatg atgttgttgt
   107221 gccaaacgta tggcatcaac agtaccttga acatttactt tttcaaattc atcatcatca
   107281 ccaaaatgat ctgtacgagc acctgcatga ataatcgtat ccatgttttc tggtaaaaca
   107341 acatcatcca tacactcgaa atcaccaaca atgacttcaa tgtttgataa catcatttca
   107401 accgtctctt ctgaaaaata atcatttaaa ttcgtcatca acttatacca tgctatttcc
   107461 tcattatcag cacgtatgaa acaataaatg cgatgactgt atccttgtag tgcttcaatc
   107521 agataagcac ctaaaaaacc tgtcacgcca gtcaatagtg tatttcctag aggtcgatga
   107581 cttagactat cctctaaaat acccaagtta taacgagaca taacaatctt ttgtaattcc
   107641 gaaagattat ccggtaatgc aactaatgat tgttgatttt ggtacatata attaacaatc
   107701 tgtcgcacgg ttttatattg gtataatgtc tgcattgaaa tatgatggcc aaatcgtttt
   107761 aaatgcgaga caactaacat cgcctctaat gagttaccac caagttcaaa gaaatcatcg
   107821 tcaacaccga catcattttg tttcaatacc tctccaaata catcaacaaa tgtctgctca
   107881 atttcattag agggttcgct atacacttta ttagactgtt gtataggtga tggatttggc
   107941 aaacgcgtag tatccacctt gtcattcgtg gttaatggca tacaatcgat atgcgttata
   108001 gtcttaggaa tcatatactt aggcagatga tcatttaaat attgcttcaa atcctgctcc
   108061 acttgttgct ctccgacata ataagcattc aatatatcat gcgtatcaaa gtgacttact
   108121 gttacaacac aatcagatat accacgaata gctaatattg cattttcaat ttcatcaagt
   108181 tcaatacggt acccgttaac tttcacttgt ttatctattc ttcctaaaaa ttcaatttga
   108241 ccatcagatg tataacgtgc taaatcacca ctatgataca actttccttt accaaatgga
   108301 ttattttgcc atttatcagc cattaattct ggacggttaa tatatcctat cgctaaacta
   108361 tcacctgcaa tacacaactc gcctggcata ccaataccgc ataacaaacc atctgacata
   108421 atatacactt ggatgttaga taagggtttg ccaattggaa tcgtctcagg tatcaaatca
   108481 ccacaatgat gtgaccaata cgatgtgatg actgttgact cagatggtcc ataggcattg
   108541 aaatacgtgc cacaatgctt ctcaatatat ttaacaaagg atgccgtact agttgccccg
   108601 cctgtaatca acttttcaat ataaaagtct tccataacac tacacatctg taacggaatc
   108661 gacgccaccg tcacacgatg cttattaatg agttgttgta actgtgctgg attaacacgt
   108721 tcctctctat ctggaatcac aagcgtatga ccatttaaca aacaacaata aatctccata
   108781 actgatgcat caaaaacaat atttgcatgt tgcaaaaata cttcattgtt gcctaattgc
   108841 aattcagttg accatgcatg cactaaattc aacaaatttc gttgtcgtat ggcaacccct
   108901 ttaggcatcc cggtcgtacc agatgtgtaa atagcataca tctcattatc taacatcgct
   108961 gtgttttcaa gttgattgcc atgtaaatca tcatattgtt cattttcctt tgattcaaca
   109021 aagcctttag cattttccaa ttgaatgact ggtaatgtcg tttcaatttc aacgccataa
   109081 gacatgactg cagttacttt agcatcctcc aaaattgcac cttgtcgttt attcggaaaa
   109141 tcaatatcga taggtatata agatgcacct actttaactg tcgccaacat cgccgcaatc
   109201 atttcaaaac tacgttctgt aaacaaggca acccgttgac cattgcccac accatttgat
   109261 aggagcatgt gcgcaatggc atccacatag ttgtgtaatg tttcatacgt cattgtcaaa
   109321 tcattcatga ctagcgcaac atgattacct tgtcgtgaga cagcttcatt aaagtaactt
   109381 atgatagatt tatttcccgg gacattaagc attcgatcgt taacatgcgt attgacccaa
   109441 tttagaagtt cctccgtgcc gtttggtata tcacaaattt gtagtgtatc ttgatgcttc
   109501 aaaatataat caatcataat catacattga ttacccatgt gacgaactgt ttctgagtga
   109561 tataaatcgg tattatactc gatattgatt atatagtcat cgcgatcttc ttcaatgatg
   109621 aaagataaat caaatttcgc cgtcactgat ttgggttgaa tgtgtgttaa tttactatgc
   109681 ccaaaatgag catgattcgt ttcattgttt tgtagtacta acatgacatc aaataatgga
   109741 ttccgtgagg catcatgtga ttgatctaag tcatttacta aacattcgaa tgggtattct
   109801 tgatgctcgt atgcctccaa actcatttcc ttaacctctt gtaaaaactg tgtccacatt
   109861 ttatcaggtg acggttgccc tctatatacc aacgtattag caaacatgcc tagcatttgc
   109921 tccgtgcctt tatgcatacg cgcactcatc acactaccga caacaacatc atcttttcga
   109981 gcatatctgc ttaacaacgt catgaccaca ctcataaaga acataaaatc agtaatttga
   110041 tgcttttcta catacttttg aagtagctgt ctcatttgtt gattcattgt aaatgacatc
   110101 attgctccat ttgtcgtttt aatatttggt ctaacatagt ctgtcggtaa gcttaaaata
   110161 ggtacttcat ctttgaattg agataaccaa tattgtctat gtttcgtcat atcacgatgc
   110221 gacatccact cactatagtc tttatattgc aatttaagtg gtaacaataa tttatgttga
   110281 taaagtgcgt taagatcatt cattaattgt atattactca taccgtcatt aatgatatga
   110341 tgtgtatcta taaacaggta tgcatgtaag ggacttctaa tgtatctcac tctaatttga
   110401 cttggctttt ccaaattaaa aggtgccaca aattggcgca tgatttcttg ttcatccgta
   110461 aaatgcgtgt taacttcttc aaagtcagct acaacatctg ccacaatacg ttgtcgaacc
   110521 tcatcatcta caacaatata ttgtgttcgt agaatctcat gtcgcgctat caaatgctga
   110581 actgcttgtt gcaattgagc tacattaagt cctgatgata accgccataa aaaaggtacg
   110641 ttatacaccg tatctttatg gtttgatttc cataataaat acatacgctt ttgtgcagag
   110701 ctcagcacat aatcatcttt aactatagct tctggaatca cttcatagtt ttgttcttga
   110761 accttagcaa tcgcttgtgc tagttcaaat acagttggct tttgtaataa atcaccaatt
   110821 tgtaatcgtt tcccagtaga tgcctctatc cgattcacca ctaacgttgc ttttaatgaa
   110881 tggccaccta attcaaagaa attatcatga atacctactt gattcacatg taaaatatct
   110941 gcaaaaattt ggcatagcaa gtgttcggta tctgtactcg gtgctacata ggcatccgta
   111001 tcgacatagt ccatgatagg caatgccttc ttatctaatt tcccattaat agtaatagga
   111061 atttgctcaa tatgcatgaa attaactggt atcatgtact ccggtaaggt catacgtaat
   111121 tgtgatttaa tcttattatg tgataatgta tgcatcgctt cataataagc aacgatatac
   111181 tgatcttgat catgattttg aacaataaca actgctttat taataccttg tatacgctcg
   111241 agcgcatgct caacctctga caactcaatc ctaaaccctc gaatcttaac ttgtttgtcc
   111301 tttcgatata aataatctat gttgccatcg ggtaatagac gaacgatatc accacttcta
   111361 tacatcagct gatttatatt tgaatctttg ataaatttat ctgctgtcaa ttctggctga
   111421 tttaaataac ctgcagctaa cccaaagcca cttgtacata attctccagg aataccaacg
   111481 ccacatcgac actcgccttg catgatataa acatgagtac caagaatcgg tttaccaata
   111541 ggaatacgat ttggaacttt gttaggtata ttatacgtcg ttgtaaatgt tgtattttca
   111601 gttggtccat aaccattaat aatttgagga tgcttcggtt tttgattaag caaatccacc
   111661 cacttagcat tcaatacttc tccaccaatt aataagtact ttaacggtac caatacttct
   111721 attcgttcac tagcaatctg attaaataat gaggaggtta accacatagt attaacgtca
   111781 ttttcattga ttaattgttc taacgctatt ggatttaata attgttcttt tttagcaaca
   111841 atcagctttc caccattgag caatgcacca tatatttcaa atgttgcagc atcaaaggct
   111901 atagttcctg ataacaaaat cgtcgtctct tcatttaatg gtacataatg attttgatgg
   111961 accaagcgaa caatacctcg gtgcggaatt agtgtacctt ttgggttacc agttgtcccc
   112021 gacgtgtaaa taacataagc atgatcttct aacgtgttac atttagaaag attatcaata
   112081 tttttccacg ctatcttatt caaatcaatg tgattaatat tttgtttacc attttcatat
   112141 aaagcttggt acgttattac aactttaggc gttgcatctt ttaaaatgta ctcctgacga
   112201 tcacttggat agttcggatc aattggcacg taagccccac cagctttcaa cacacctatc
   112261 atcgctatta tcatctcaat acttttttca gctatgacag cgacacgatc attaggttca
   112321 acaccatact ggtttctcaa acggtgtgct aaatcattcg cgcgtgcatt caatgtttga
   112381 tatgttataa acactccgtc aaattgcaca gcgacatgat tcggcgttgc ttcaacttgt
   112441 tgctcaaata aggtaacaac tgtttgcgca tcatctatct caggcaaact tacattgata
   112501 tcgtcatata attgaatatc acgttctgtc atcaaattaa gttcatctac agttgttcgt
   112561 ttatttccat tttcttcagt aatttgcaaa taaatatttc gaactaagtc actcagcgtc
   112621 tcgattgaga gcaaatcata tgctgcactg ttatatataa ttttgaaccc gtgttgatgt
   112681 ggaaaaattt caatatccgc taaagatgta tgtgcatcat gtatttgatg tacatcctca
   112741 ataacatcat tacaacaaga catcatatga tgataacaat gaaaaatagt ctctagtgaa
   112801 agcgaagaat tcgcgcactg taattgcgac atattttgca acacacattt attaaaatct
   112861 gttgtaaaac gttgacatac atcttttgca tcgattgtta acgttaacgg cacaatattt
   112921 ccgtgtaaat catttggtaa atgtgatggt acatgtatac ctaatgtgac atcatgttgt
   112981 tgactcatta tatgattagc taaatacaca ctaacagcca acgatgccat atctattgat
   113041 gtcatatcat caatcaaata cgtttgatat aaagcttgct caaatggatg cttaattggt
   113101 aaataactat caatatggat gtcagagtta ttctctaacc gaaaatagtt tgagtctaat
   113161 gctatatgcg atgcatcttg attgtgctta tcatcatttc tatttaaatg tgcatgctgt
   113221 cgagtattgt taataacagt attgccacga tatgcattgc ataaatcatc aagaaaaata
   113281 tcaatttgac tatcatcgaa aatggacaca tgaaaatcta atagtatata tgcagcatca
   113341 gcgaactgaa acaatttaaa tttgaataaa ggtgaatcat taaaatggta agtacttaat
   113401 tcttgcttaa aaaaagcttc taaatcatag tttgcggaag aagttggaac ttgttttatc
   113461 tcaataaaag gcagaaattc atgaagtatc attgttaaat tgtcatcggt agtaacatca
   113521 aaaaaatgtc ttatagatgc atgttgttgc acaattgtcg ataatgcata catcatttta
   113581 gtagcttcaa catttttagc gagtttaacc caatacgcat tacggtgtgt cgttgattct
   113641 gtattatttt tgtatatacg aaaatattcc tgctgaaatc tcaaattacc cataatcata
   113701 aaaagtcctt ctttcatatc ataatactca ttacttactg aaattgcatg atgatatgat
   113761 aaccgacgaa atgttaatta actcgttatg taatgattaa tataaaacac cattcgcaac
   113821 atatgagcga tatattctac cctaaaatac atcttgtatc atcgttacaa ttggtatatt
   113881 tttcaatgta aattacatac atcttcgata aatagtacac tacaactcgt taatcacttt
   113941 ctgttgttca catctcattg caaattcaat attgttgtta caaaatatcc atgaagcaag
   114001 tttatattaa acaaacaact cgcataaaac aattgttatc cttaaatttt aacaaattct
   114061 taataaattt atctctattt taattacgac cgaattaata ggttttcaat ataaaaagat
   114121 gcataaaata aatatttaaa taaattcaat ttgtattcac ttgtttttgt cccccgaata
   114181 caccagcaac aagcatgcta gcaccaattg ttaaaacgat aaacatatac agtcccattt
   114241 gtaatgacgt taagaaagca cccaacacaa tccctaacct agctagtgtt tctgaaaaat
   114301 gaatacctaa tgcattaact gcactatatg ttcctctttt agctttagga ataattttaa
   114361 agcgttgttc tgaaactata ggcgaataaa taatttcacc tacagtcgca attatcataa
   114421 aaacaactaa taagccaaac tgattaagat aggttagacc actataacca acaatataaa
   114481 tcagcaaacc agtgattaaa gcttttttaa aatctatttt caatacaact ttcgagattg
   114541 aatacgtgag taaaatgacg acgaccgtat taatcattag caagattgct aacatcttag
   114601 cacctgtaat atcatatgaa cctatactta ttgtttcaaa ctgattcttt agtctaatag
   114661 caatatatga ggagattgaa aattcaccca tcatgatgat actgaacccc gaaatcaata
   114721 acatataatt acggtctttc aaaactaatt tataactgcg aaatatattc attatttgta
   114781 atttttgata acgacttgca tgcctcttgt catcactttg ctttacttga tttcggtctt
   114841 gaggtaacca aatatataaa ataaagagta caattaaaaa tatacaagct gctattaaga
   114901 aaagtagtaa catactgtag ccatacatca agccgcctaa caatgcccca atagctaccg
   114961 ataagttcgt catccaatag ctaatcttgt aaatataatg ttccacgtct tcggtaattg
   115021 catccataat taatgtgtcc ataactggaa attgtaatcc ccaaacgatt gtaaatatgg
   115081 catatgcaac acaaaaacca ataatttgcc acaattgatg tgacccaaat atgcccatga
   115141 acacaagcat tatcaccatc gtcgcttgat aaataagtac tagcaacttt ttcggaaata
   115201 tctcaataag gtaaccagat ataatggaca atggaaattt tagaaccact aaaccaacaa
   115261 gatatatacc gacaattgat tgacttaaca tatctgttaa atatagtgct ataaacggta
   115321 taaatgctgt cgtaataatt agctgtaaaa aattgctaat caatcgtact ttcaaagtcg
   115381 tacttaagcg tttcattaat aactacaccc ctatccacat atatacacac taccatttat
   115441 ataaaatcta ttattagatt atacgttgaa acaaagaatt tttagttata caaagttatt
   115501 taacaaacaa atgcatcgac tttacaatgc atcttgcata taatgcctca aaaaaattag
   115561 cactatatga ctatatatta ttccaaatga atgaaattta tcaataattg cgtaagtgaa
   115621 cacatatgtg cgtaaatgtt aaatcattgt cctaacatag ccgtgactat acttagatgt
   115681 aatcataaaa aaactactgc catctttaca acagcagtag tgcttatata attcatttat
   115741 ataaaattga aagcgttaat cgctagccca gcatccttat tctatttagc tgtataactt
   115801 ttactagcaa tacgaccact tgcaacaata atatctttat cttggaaagg ttcatgattg
   115861 aagaaacgct ctaaaatatc tttaactcca tcttcaatac gtttttgtgc ttctaaagtc
   115921 atacctgaat agtgaactgt catagcattt ctaggcattg ttctccatgg atgatcagca
   115981 ggtgcaggtt gtggatacca aacatcacca gcatatcctt gtaaatgctc ggatgctaac
   116041 gcttcaacta acgcatcgcg atttacaatt ttaccacgtg cagtattcac taaataactg
   116101 tgttttttca tacgacttaa aacatcttta tcaaataagt tatcagtttc tggtgttaat
   116161 ggtgcatgaa ttgtaatcgc atcacttgtt gaaacaagtt catcaaagct tacaaattta
   116221 gacaatttat ggtcttgttg attgattgga tcatagtgtt gtaatgttac attaaatggc
   116281 gctaatcttt cagcaacaag ttgtccaatt cgaccaaatc caaaaatacc aattgttttg
   116341 tgttgtaatt catgcgcatg attacctact tgagacaagt tccattcacc ttctactgat
   116401 tgacgatgac cttcttcata gtttctaaga agtattaata aatccataac cgcatgttct
   116461 gccacactaa ctgtattact tcctgtaact tcaacgacac caatattgtg ttcacttgct
   116521 gccgctaaat ctacatggtc agatcctaca cctgctgtaa ttgctaattt caagttcggt
   116581 gctttttcaa tacgttcacg agtcatatat gcaggataaa atggcgcact aataatcaca
   116641 tccatatctg gtaaatgttt atctaagtct tcaccattat ctgctaatat aatgaactca
   116701 tgtcctcttt cctctaaaaa tgtttttaat cctaatgctt ttttagtatt aagtaattga
   116761 ttttcttgac cttctactgc ttctggaaat aacgctacga ttttcatatc catctctcct
   116821 aaatgataaa ttttgacttc cttaaagtac gtgttgcatg ttgcttgttt taaaaatatg
   116881 acaaaaaaac ggcaccgttt gacataccac ccccttgaat tattgttaaa ttcaaagcga
   116941 agttagcaaa cagcaccgtg taccttacac cagcaacact tattctattg acttatcgaa
   117001 aacaaatatt gaaatgactt catcatcatt caaatcaata tctgtaaata attttacgaa
   117061 cttagcgcct acaagacttt ccatctcatt tacatctatt tctttataca tctgtttaat
   117121 cttctctgtg cgtgtataat ggagcatcga ttcattgcgt ttgtcgttta ggtaaaaact
   117181 ctcaacttta ctcaaaacac ctgtcatatg tgcaatcgcc caattatctt taaacgacac
   117241 tcgaatacta ttgggtcctt tacccacgta ttctttacga taagatctta ctagattcga
   117301 gaattgttgt tctttagtat gcgtatctat agtattcacc ttctttaaaa taagaagttc
   117361 attaattgtt cacattttca ttatacacct tataaacact ttttcaatga taacgattat
   117421 tattattacg aaatgtatat tttcctagtt aaaaggatat aacaaataaa cagaaaatgt
   117481 ttataaacta agatttatat tattttaaaa aatgtttcaa caaacgcatc taaacaacag
   117541 atcagcatat catacttacc ccttcaactc tgcctcaagt ttacctaaat gtcttaatgt
   117601 tggtgtcaat gctgcgaaga agaatccttc ttttaacttg cgaacttgtg gcgaatatgg
   117661 tgtgtacgct cttgaaccac cattgacaac agaagcttga tttacatcta acaataaata
   117721 gccaatgttc ttcttcaatg atattaattc acttaaatgt gaagttaagt taccgtcatc
   117781 taatattgca taatattcct ctctaagttg acgataacgt tttttaaaag cttcaacatc
   117841 atactctaaa tattgattta ttccgttttg cgcatttgaa aatgcatcaa ttaactctaa
   117901 agaactttta attgagccta atcctattgg aatttggtaa gcaataaatt gcgggcgaat
   117961 agttgccgca aactgcttcg catcatgcgt gatgatttgt gattgtggca ctacgacttg
   118021 attcaatgtg atttgatacg ttgctgaccc gttgacccct aaaaaatttg ttttttcaac
   118081 gagagtgata ccatcttgat tggcacgtag aatgaacatg acaaattcat ctgatgattc
   118141 atgtttcgaa atcgcaccaa aataatggtc ttcttgaata ttacttacag ctggcatacg
   118201 tccactgaca accaattgtc catcaacata agtgtgttca aggttcaact tttctaaatc
   118261 attaaatgac ttcatcggat tagacaatcc ggtagcacct aatatttctc cagataacaa
   118321 ttgctgttgt aagtcattat ttaaatgtgg ctgcgtggca ttttctaaat acgttgaaaa
   118381 agctaattgg caccataaac aaaatcctgt tgtcaaacaa gactgcgata cagcttcgat
   118441 tacttcagca ttttttctca atgccgcctc accgaaataa ccatctacaa ataattgttg
   118501 aataaatgtt ctcggataat acgtcccttc atcaacttct actaaatgag gatctaattg
   118561 ttctttgata agcgtttcta aagtcatcat catctctcct tattcaccaa atcttctaag
   118621 tataaactgc tcaatataac taatgaatcg atcaataata aaaccaaata atccgataaa
   118681 gaatattgct gctaaaacat cttctaagtt caacatattt cgtgcatcaa cgattaaaaa
   118741 acctaatccc gattgtgcac caatcatttc accagaaact aaaaatatcc aacttgttcc
   118801 taccgccata tgtatcccag ccatgatttg tttaaatgcc ccgggaaata atatattgcg
   118861 atacaatgac cacccagtta aatttaaatt tgccgctatt tttaaatatt gaggttcaat
   118921 gtctctaacg cctttaatag tattgaacac aattgggaaa aaagcagcga taaaaataat
   118981 cgcaatcgct ggcaaactac caataccaaa ccatagaaca acaaatggtg cccatgctat
   119041 cggagatatc ggcctaatca attgaaatag cggttcgata gcgttgtata gccaacgatt
   119101 ccttccaagc aagaagccca atggaatagc aaccaacaat gcgacaacaa agcccgctac
   119161 aaatctccat aaactaattg ctaaatgttg gaaaatttct ccagtaacaa tgaaagtcca
   119221 tatacttttt cctacaagaa caggaccagg taacaataca ggttggtaat gcccaataat
   119281 aatgaccatt tcccaaatgc ctaagaaaat aataaatgtg ataataggta atataaattt
   119341 gttatttgtg ggacgtgtca tgaacgcgat gcctccttat acaatgacgg ttcaacaaag
   119401 tcatcatatg caggtggatt aaacaaatga tgttgtttta ccaatgtcgt aatttcttga
   119461 tagccggatg gcttaattgt taaatcacca taggatgtcc atgccgctga ctgtgttaaa
   119521 acgtcacgac tttgtttaaa atgatgcgtc ataatgtcta cactttgctt gcgatcattc
   119581 attttaaagc cagacttttt ataatcttgt acaaatgctt gcgctacatc cttgtgttga
   119641 tcaagcaatt cccctctcag tactagcaca cagcaatacg catcaggtat aacgtcatca
   119701 ccatgtttca aagtcttacc tttgcctaac ttttcaccca gtgcaccgaa tggttcggct
   119761 acagaatacc ctgtaattct gtgttcactc aatgcggctg gcatttctgc tggcgacatt
   119821 tcatgatagc taaaatgccc cggtttaatc tttaattgtt tacgtaattc ctcaagtaaa
   119881 agataatgtg ttgaataacg atgtggtata ccaaaatggt aatcatcgcc attattatta
   119941 aattcattta agtgcatacc tttttgtccc ataatgacat tgccttcatg atggcccaat
   120001 gccacagcct ttatatttga gcccttctgt tttgatttca tcgctagctc tattaaagtt
   120061 gatgcaccat caatacgacc actgtttaat gcgtccatta aatctggcca attattgaat
   120121 ttaactaatt ctagtttata tttcggatga ttgtattgtg ataataattt tttagtcatc
   120181 atcaaattag ctgaatgtgt aatcggcaaa tatccaattt taatcacttg ctgattttgg
   120241 gcatttttag acggttcttt agacgtcctt tgccaatcgc atcctgtaat tataaagatt
   120301 ccaatgatga cgattatgct taaccttttc atcgtcactc actccttata aataatattc
   120361 aggttcaact tgatgatgat tcaatgcaaa tgtttccata atttcattac gaatcttaag
   120421 taggtggcta tcattacgac tgcgtggatg tgatgctgta atttcatatt gagaaataat
   120481 attgcaccct tcacctaaca gaacaatgcg gtcggaaaga taaatagctt catcaatgtc
   120541 atgcgtcact aaaataatag ttgattgcgt tttatgtttt agttgcacta gttgatcctg
   120601 aagtttataa cgtgtaaatg catctaatgc acctaatggc tcatccatca atataacgtt
   120661 aggcttatgc acatgcgctc gacatagtgc cacacgttgt ttcatacccc cggacagttg
   120721 ctcgggaaaa tgctttcccc tgccttctaa atcaactaat ttaagctgtg cgttaatctc
   120781 ttcatcacta attttctgtt ggaatccaat cctaatgttg tcattaatcg ttttccatgg
   120841 cagcagatta tgatgttgaa atagcattaa acaatctgga gacggctgtt gtttaatttc
   120901 gttatcaata atgacacgac cagatgatgg atgaataaat ccaccgatga tattgagtaa
   120961 agtagacttt ccgcaaccac tttttcctat gaaagtgact atttctccct tgctaatgtc
   121021 caaattaaag ttatgaatta ctttatgtga tccaaagtga tgttgtaatt gttgaatttt
   121081 aatcatgaca agcccccttt taatccctac tattttaata ggaattaagt gtatatctaa
   121141 agggctatgc caaacacagc ccttatatcg tgaattgtta tatctataga tgattatggt
   121201 ttggtatgag tgctcttata acataagcgt tattcaatta acgacgttat attaatttca
   121261 gctctactaa atttcaataa aatgattgtt ttagacaata cttgcattta gttcattagt
   121321 ttcttcatat caactactta catttatagc attgagctat tctaattaac tgcaatcgaa
   121381 atccacgtca aacctatata catatatctc atcaacttgt tgtcttatta aagtttttcg
   121441 atgccatcaa tcggtgtatc aactgctttg cgcgcgcgac gtaccgcttc ttcatcaggt
   121501 gcgttgtata aacaaataca tttagacata tcttcacata catatgtgcg tttaaattca
   121561 acttctggca cttcttcata atgaacagaa tttttctttt tacgtgctaa atattgatcc
   121621 atcgtaatgc cttccggaat gttccaagtt acaaggtaat caacatgtgc atcaccattt
   121681 ttaacttcat ctaaatcttt accaactaag cgtacttctt tgactaattg aatactaata
   121741 tctgcttctg ttaaaaattg tttagcttct gcttcgtcat ttgcttccac aataaaataa
   121801 ccatgagtta aattttcagt agcttgtact tcaattaatg ttggaattgt cttcgtagat
   121861 agtgatgctg cctttgcttc tagttcttct ttcgttgatg caaaatcaag attgttagct
   121921 tctaataaaa ataatgtcat taataagacc tcctataaca atggttgaaa aaatattact
   121981 ataattctta tcagattaca aggatattaa gctatttttt taaatattta gataaaattc
   122041 tgtaaaatat attttcaaag agtataaaaa taatgttagg gtataagtaa ataaacatat
   122101 atataggggg ctatcattat ggataaagaa tctgtcgtag caagtttagc aagaaacaaa
   122161 aagattgctg tagaaacaat gaccggtcaa aggtacatca tagaacgcat tttacataca
   122221 aatgatgaaa aacatattca tattttgaaa cctaaagatg tcgtgttaga tgtagatacc
   122281 atcaaagaca tcgacgaaaa tcatttagat gatgcaacat aagtataaaa cgaaacgtgc
   122341 gcctatgaca tagattaatg ttttaggcgc tacaatgttt tatttatgtt aatttgtcga
   122401 agtatggctc atctaatgga ttcaattgca agttttcaat ttgcaacgtt gaatgtgcaa
   122461 tgccatattt ttctttcaac aatgatgata cttgatcaat cgcttgataa tcatcaccct
   122521 catatttttt atctaacaca acatgggcgc ttaatgaata atgctctgtt gtaatactcc
   122581 acaaatgaaa ttcatgtaca tctaatatgc catctatgtt tttaatatct gccataattt
   122641 gatcagtatc caaatgttga ggcacacttt ccattaaaat taaccacgca ttacgcgtaa
   122701 ttttataacc accacgtaaa atgatgagtg aaattacaat actaatgatt gggtcgatga
   122761 tgcgccatcc tgtaaagtaa atcaatacaa ctgcaacgat gacaccaata gagttcaata
   122821 agtctcccat gaaatgccat aatgcacttt gaatattgat attgtcttct tgttttaaag
   122881 accttacaag gataacagtc aaaataatat tgacgagtaa accaatacta gcaatcataa
   122941 acataatgcc actttcaatg ggttgcggat aaataatacg tacaatagct tcatataaaa
   123001 tccaaattga aatcacaatt aatgctaatc catttaaaaa tgccgctaat atctcaaatc
   123061 ttaaatatcc gaatgtgtag cgtgcagtcg gcttcttact agcaaaataa attgccaaca
   123121 ttgacaaacc gagtgctaat acatcactaa gcatatgaaa tgagtctgac agcaatgcta
   123181 atgaattaga tactaaacct ccaacaaatt caatcactgt aaataatagt gtgatgataa
   123241 gtgatgccca tagcgtcttt ttagaacttt gttgaatttt ttgatgatcg acatgatgaa
   123301 aatatttgta tctgtttatc gtattcgcct ttttcccatt catacgtttg ccactcctaa
   123361 ataaatgcgt cgtatttaat attgtcgctt ttaaaaataa ttctttatag cttctcagat
   123421 taatattaat gcttccggaa ttaaccataa tttatacacc atcgttcttc tcatgacaac
   123481 tcattaatct ttacccttta tacctttatg taatatcacc ttggaaaaaa ttttgcagca
   123541 cactcgctct ttgctttaac cctagcatat agaaattttt aataatgtac gagattattg
   123601 tgtgagttac ataaaaatga caaaaaagta tctcaaattt attgtttagt ttcattaagt
   123661 tcaaaaaatc gcaataactt ttatgattgt tccacatatt aaaacaaacg atgactttgc
   123721 atattgaact tcatatttct aaatcaccat aattcataaa caactctgtc cttataatag
   123781 ccgcatcgca aattagcata attaaaaaca gcagtaagat gatttgcaat taaaaaccat
   123841 cctactgcta ttattttagt cattatatcc taatatcatg atacgtgttc ctaaatattt
   123901 tgtttcgctt aaaatctaaa caactccgta aacatgctaa gacttaccgc tagactgcct
   123961 gcaaacacgc ttcagaaacg atatttattc tagtacaaac cttttaaagc attgcttgta
   124021 tcaatataaa tatttttaac ttgttgatag ttacttaacg cacctttata agtttctcga
   124081 ccgatacctg attttttata accaccaaat ggtgcgcctt ctggtacttg gttgtaagtg
   124141 ttaatccaaa tacgtcctgt acgaacagct ttagcaatat ttaatgcacg tgtgatattt
   124201 tgagaaaata cgccgcctgc taaaccatac tctgaatcat tagctatatc aattgcttct
   124261 tgatcgtcct tcactttaat cactgttaac actggtccaa atatttcttc ttgcgctaat
   124321 ttgtgatgat tatctggcac agcaattaat gtcggttcaa agaagaatcc tttatctaac
   124381 ccattttcag ttaaacgatg accgcctgct aaaatttgtg catctgattc ttttgctgca
   124441 tcaatatatg attgaatttt atctaattga tccttaccag tttgactacc catttgtgta
   124501 gcttcatctt gtggatctcc aactttaata tttgaaaatg cctcttgtaa acgtggcacc
   124561 aattgatcat aaattttttc atgaactaat aatcgagaac ctgcactaca tacttcacct
   124621 tggttgaata aaatacctaa ctgaatgcct tcaactgcaa ggtctaaatt agcatcatct
   124681 aatatgatat tggcgctttt accaccaagt tctaatgtag cgggtactag atgttttgct
   124741 gcagcttcgg caacttgata acctacatca gttgagcccg taaatgataa tttatctaca
   124801 ccatcatgat tgaaaattgc attacctgat tctgaacctt tacccgttag tatattgaca
   124861 acacctttag gtaatacctc ttggaaaatt ttagcaactt ccaataaact taatggtgtt
   124921 gaagacgaag gttgaatcac aattgtatta cctgcagcaa tggctggcgc aatcttccat
   124981 gcagctaata gcattgggaa gttccaagca acaacagcac ctacgacgcc aatcggctca
   125041 tgtcgtacga tactcattgt gtctttatcg atatcattca ctgtaccttc ttctgtttca
   125101 ataacacttg cgaaataatg gaaatgtctt gcagcaaatg gaatatcaat tgctgttgtc
   125161 tcacgaatcg gtttaccatt atttaatgtt tcaatcattg caattttatc tttttgtgcc
   125221 attaatttat cacaaatatc acgcaacatt tgtgcacgtt ctgatttaga agttaatgac
   125281 catgattcaa atgcctcttg cgccacttcg actgcataat cgacatcttt atcttttgct
   125341 cttgtaatat gtgatagtgt ttctccagtt gctggattag tcacttcgat tgtttcgtca
   125401 ctgctacctt taacaaattc cccattgata aataaaccat aattctctgc tatataatct
   125461 cgaacgttta ctgccatatt atctctcctt tgtttattgg ctataatata aatctcttag
   125521 catcatattt aataatgctt ttaaacgata tgattcacat tatatagtaa gcgtttacat
   125581 tttataaaat aatcagctca cagaagtctc atttttaaaa cttttgcgtc gtttttgcac
   125641 ataaaaataa tcttattttc gaaaacatat tgcacttttc aaaaataaaa cacataatat
   125701 aactataata cttgagaata attctcatta aatagtttag ttgttatgaa agcgcgctta
   125761 aaacgcgtta atgggacaag gataattcaa caacgtttca ttttactgag tcattgcact
   125821 tatcatacac attatattta gcatgagtta tattactaaa ataatattac atgcgcaata
   125881 gtactagaat ggagtttttt caatgcgact tattttaatc gtcattggct taatatttac
   125941 agcgcttggt attgcaggtg ccgtattacc tttactgcca acgacccctt ttttactcgt
   126001 agcagttttt tgttttgctc gaagttcaga tcgcttttac aattggctta ttaatcaaaa
   126061 aatttataaa gaatatgtag aaaactttta tttacatcga ggctacacgc tacaacagaa
   126121 aattaaaatt ttaattagct tatacattgt aataggtttt tcaatttata tggtggatgt
   126181 tcttgcagtc cgtgtaggat taatcatcat ggttatcata cagaccgctg tactctttac
   126241 atttgtaaaa acattaccca aatcaaatca taaaatagag gagtgattgc ccatgtttat
   126301 ggcagaaaat agattacaat tacaaaaagg cagtgcggaa gaaacgattg aacgttttta
   126361 caatagacaa ggtattgaaa ctattgaagg cttccaacaa atgtttgtca ctaaaacatt
   126421 aaataccgag gatacagacg aagttaaaat cttaactatt tgggaatctg aagatagctt
   126481 taataattgg ttgaattccg atgtatttaa agaagctcat aaaaatgtac gtttaaaaag
   126541 tgatgacgat ggacagcaaa gtccaatatt atcaaataaa gtattcaaat atgatattgg
   126601 ctaccactat caaaaataaa tatattaaaa acccctagtc accgctggtt gtctaaacca
   126661 acttcatgat taggggtttt ttattatttg tgacgtaaag gtatgaattc atccggcttg
   126721 tctgagcgca atccaaaata atattctatt gcttcacaaa tacgttgtga tgcttgtcca
   126781 tcaccatatg gattattcgc ttgactcata cgttgatacg cttcatcatc ctcaatcaat
   126841 tgtttcacat ttcgaacaat attgtcataa tctgtgccaa ttactctcga tgttcccgcc
   126901 tcaacgcctt cgggacgctc tgtatgattc cttaatacca acacaggttt tccaaatgta
   126961 ggagcctcct cttgaatacc accagaatct gtcagcacga ggtacgattg atttgtaaaa
   127021 ttatggaact caatcgcatc taatggctca attaattcaa tccgatttct cccagataaa
   127081 tatttttcgg caatcgctct tacctttgga ttacgatgca ttggataaat gaagacaaca
   127141 tctttatatt catctgccaa atctcttact gctttaaaaa tctgatgcat cggttcccca
   127201 atattttcac gacgatgcgc tgttagtaaa ataactttct tgcctttatg tttattaata
   127261 atcgttgaaa caaaatcatt ttgaactgtt gttgacaatg cgtcaataac tgtatttcca
   127321 gtaataaaga tactctcttt gtctttgttt tcaaaaagta aatttttagc tgcaattact
   127381 gttggtgcaa aattcaattc agcaatatta cttaccatga ctcgatttaa ctcttcagga
   127441 aatggcgagt atttctgatg tgttcgaagt ccagcttcta catgtccgac cggaatttga
   127501 tgataaaatg ctgccaaact tcctacaaaa gtcgttgtag tatcaccatg tactaaaatc
   127561 atatccggct gttcctcatt aatgatgcta tcaagtttag caagcgtatt cgcggtaagg
   127621 tccgctaacg tttgttgatc ttgcataata tttaaatcat gatcagcttg aatatcaaat
   127681 atacttaaca cactatctaa catatctcta tgttgtgctg taatcacaat gttcgcttca
   127741 aagttcccat tatgatcaat ttcttttact aatggcgcca tttttattgc ttcgggtctc
   127801 gtaccgaaaa taaccataat ttttttcata acattatcct ctctgaagtt caaacacata
   127861 acagcttatc tttccttaat catgtatgcc ctagtttgac acattttatt tgtcgataaa
   127921 attaaatata ttgccataat tataatacga tacatcttca aatgatgatt tcacaacatt
   127981 ttttgtatca aaaatcactt tatgcttcat tttatcaaaa tgactgtccg ataaattttt
   128041 aaattctgag tggtcactta aaatcaatac tagcgatgcg tctttgacag catgtgacat
   128101 atcatgttct acaaaatcta atgcaacatg tggatcataa gcacatactt ctatgtctgg
   128161 ttcttgattt aatagctcat aaatatcaaa tgctggtgat tctcttatat catcaacatc
   128221 acctttataa gttaaaccaa atactgtgac tttattcccg ctcaacgctt taatgatttg
   128281 tttcgttgta tcaacaacat aggccggcat tgaattatta atttcacgtc cagtttgaat
   128341 taactttgca ttttcagggt ctttagcaat aataaagtac ggatcaacag ctaaacaatg
   128401 accgcctaca cctggaccag gttgatggat attaacacgc ggatgtttgt ttgccatttc
   128461 aatcacatct aatacattaa tatttaagtt attgcaaatt tttgttaatt cattagctaa
   128521 agaaatgttc acgtctctat atgtgttttc cattagctta ctcatttcag cagtacgtgc
   128581 atctgtttca atcatttctc cctgaacgaa tgtgcgatag acacgtttac ccgcttcaat
   128641 acaagcttta gtcacaccgc caatgatgcg attgttatga actaattctt ctaaaatttt
   128701 tcctggcagt acacgttctg gacaatgtac taaataaata tcttcaccta ttgtaaaccc
   128761 taaattttca atgaccggtt ttacaaaatc atccatcgtt ttaggcgcaa ttgtcgactc
   128821 tacaataatg gtatttcctt tttctaaaaa tggtaaaata ctatctaatg catgcataac
   128881 tagcgaaatg tcacatgacc ggtactgatc atcattattc ggcgtcggaa cggcaatgat
   128941 aaaaacatca gatgcttctg gcgttgtaga taccttcaat tttcccgatg acagtacctc
   129001 ttcataaacc tcttgtaatc caggttcttc aatactaatt tgaccacttt gtaacttatc
   129061 aatcgtttgc tgattaatat caacaccaag cacatcgacg ccatgctttg caaacataat
   129121 tgatgttggt aaaccaatat aacctaagcc aactactgtt aacttcatac tataacctcc
   129181 aaataaaacg atttgtatgt tgattttatt taatagatga cttatgcctt atctttggtt
   129241 gtcgtttcat ccatgatgtc cgcaataaca agtgacattt ttccaggaat aacttcaagt
   129301 gcattattat tttcatataa cgtattgctg tatattaaat tgccgaataa ttttctaaag
   129361 accaacaact tattaaaata cttatttagc attgaaggca tgttgatcaa taccgtttta
   129421 tgatgtgatt ggcgacgtat ttcatacatt actgacgatg tatcaaagta aaaactatct
   129481 tgaggatgat acacgcctgt cacttctaat gatattaatt gatcaataaa tgctgtcaga
   129541 tgtttaatat ataatgcact gcgctgattg ttaatatttg gaatgattgg caatcgcttt
   129601 gacaattgca ttaaccgttg gaaatttcct gggcaatgtg caccataaat cattggtggt
   129661 ctcacaattg ctactttaaa cgaatcacta atcaactctt gtaatgcttg ttcagcgaac
   129721 tttttggaaa taccataatt ggtcgtaggg ttcattggtg tttgtgtatc aatttgatct
   129781 gatttaccaa cctgaccttc ttttccataa actgccatag tactcataaa aataaattgt
   129841 ttaacgtctt cagctttagc cttttgtgcc aattgtttcg taagcaacat attcacttgc
   129901 atataatcag atagccttgc ttgaggtgaa ttgttgtgaa ccaaagctgc tgtatgaatt
   129961 aaaacatcat aatctttgaa cgaggtcgac ttccataatt gattcctaac attaatttga
   130021 tctacttgat gtccttgttc aataagctta tcttttaaag cattaccgat atatccatgt
   130081 acgcctgtaa ttaaaatatt ttttctcatt agtgatgcac accttctgaa gtaacgatat
   130141 ttttaattgt tttatatatg atatacatat caagcatcat agattgatgt gttaagtaat
   130201 aatgatcata cgctactttt tgatcatcag taatatcatc tctccccatc acttgagcta
   130261 gtcctgtcac acctggtcta atcgtatgca cgttcgcttt tgtacgtttt tcgattaatt
   130321 cgtattgatt ataaagcgct ggtctaggac ctacaattga catttctcct tttaaaacat
   130381 tcaataattg tggcaattca tcaatagagg tcttacgaat gaccttccct gtctttgtta
   130441 tatacgatgt tgaatccatt aaatcagttg caacattagg tgtgtctatt ttcattgatc
   130501 taaacttata aatattaaac aattcattat taatcgtcgg tcttttttgt ttgaaaatgg
   130561 ctggtccagg tgattccatt ttaattagta atgctgtaat taacagaatc ggacttaaaa
   130621 ctactaaacc atatattgaa ctcactacat cgaataatcg cttcataatt atctcctcac
   130681 ttcaacagat tgtaatactt catagtatta atttctctcg tatatttatc tttaaacagt
   130741 tgatgtgcgc gctcacccat ctcgtgcaat tccttactcg agtgagtgtt gatgaagtta
   130801 taaatggcat gtgcatcgcc attatcaatt tggatacccg catcatattg ttcaacatgt
   130861 tgaacgatat cagattgctt atccatgatg agtaccaacg gtttcttagc tgcaaggtag
   130921 ccataattct tgctcggcac gcctaaaccg acgccttctt taatcagcga tgcaatacat
   130981 acatccgcaa tttttaatac gtcagcatag tctgtacctg ttaaaaactc aaacatttta
   131041 acattttcaa tacgatggtc ttctattgcc gttttgacat ctgcaaattt cttaccatga
   131101 ccacaaagta ttgttaacgt ttgaggctga tccttattta attttaaaaa tgagataagt
   131161 gtctccatat cctgtaactg ccccatatta ccgctataca ataaaatttt gtcgtattgc
   131221 tcacggtaag ctttaaatgt gtcattatag atacgattgt cttgtaattg acgcatgtca
   131281 taccagttag gaatcacatg gatattgtca gcatttttag aaatttgatg atttagtaag
   131341 tagtttttca tttccgtacc aaggacaatg acattttcag cattcttgta gacatgtcta
   131401 ttaatgtaac gcatcagctt atcaatcatg ctacctggac gagttgcacc tgtcttaatc
   131461 gcattatcag gtgctatatc atacaccaca aaagaatatt ttttcttaag cagtctgtgt
   131521 aaaacgtctg gtattaatgg caagattggt ggattagagt aaacaagaat ctgatcatat
   131581 ttcaacattt taggtatatt aatcacgaat tttgaaaata aactaaagaa attgatgatc
   131641 cttccaacct tacttttgtt attaaacctc gaatacttga gacgtcgaat gcgaatacca
   131701 cgatgcatct cggttttaga aacctgttta tgattactat attcatatgg ccatccacac
   131761 atgacatcga cattaatgtg attcgcaatt aaatcttccg ccaattgagt tggtaacgtc
   131821 gcagaagata catattccgg ataaaaatac tgacataaaa tcaaaatctt tttttcactc
   131881 atctaatcga cgtccttttt attaatgaat ttagacttta aacctataat atttaaaatc
   131941 acatacttaa taatgttgct gaacagcgtt gtccaaaaga atccatttag accaaacgca
   132001 attgtcatta aaatagttat gaatataaat gtaatcgtgt gaaacgtcat ataattcgct
   132061 tgtaatgtta ttgatgcgtg ttttgtattt aaagtttgga tcataatact cactgcattg
   132121 aataaaacac ctatattacc taaaataata aacttcgaat ataaacttga atcaatgtta
   132181 tacagtaaag agacaataat tattgtaatt ggataacata taatcatgac taaacatagg
   132241 gcagctatag caaatagatt agttttcaaa tattgtttct ttatattgtc actttcattt
   132301 acagaaatat gtgaaagcac tacattatta atcggataca gaaatgtagc taacattttc
   132361 ccaataaatg ttgaaagaaa tgatatagtt acagctgttc cacctataat tggtaataag
   132421 attaatctat ctaagtagag attcaaatta ttaaggctat ttgtactcag tagcatcaca
   132481 taatctttta ccacattatt atcttcactt tgatacgcgc ctatagttaa tccccgtaat
   132541 ttaaccaatg tatatatcgt tgcaaacaat tcactggtaa taaaacaaac aatccagttt
   132601 tgggttaaat aatatagaag tagtcctatc aacaaaccta aaaattgaat aagagcaata
   132661 tacaaaatct gattatattt taaagtcatc ctaaaaaata cattcagata aatccttaag
   132721 cacattaaaa tattaagtag aattaaaaag ataatatcga tggtgttcaa attaaaaaag
   132781 taaagaaata caataattaa agctatactc tcaatcagaa ttgaaattaa aagtatcaac
   132841 acaaatttcc agtagtaatg attggatttg tatagattca tattaatcaa tcgtatattg
   132901 ttaagcgtat tgcctaatac aacactcgtg attgttatta ttgtataaat cgttaaaata
   132961 gaaccaaacg cttcattacc tactcgttga ttaataattg gataagctaa aaattgtaat
   133021 cctaaagcta taagcaacgt accaattatt gtctttacac tatccataat aaaaactttc
   133081 ttaaccatga tgacgccgtc cttttgtaat aaaatagaac aacacaaacc aaaattcact
   133141 tacaactaaa taatttgaac taaacattaa taatgtgatt ggatagattg ctataaacat
   133201 aacgagtaaa tctatagtgt ttggatcata gttcctaatc attttataaa ctagtagcaa
   133261 aatgcaaatc attatgataa aaaaccctaa taagccaaat gatagaatca actcaataat
   133321 gatgttatgt ggtatatttc cgattagttt ataatagtta aatggcccat agcctaataa
   133381 cggactttgt tgaataaagt aaataccttt ttcataaatc ggtcctcttc cagaagtacc
   133441 ttctaaatta agtgttccac cttgtagata tgaaaatgtt ctagtattcg aaccttttgt
   133501 aaaaagaaag taaatcaata cactagatat gcttaatgca gaaatataca taatgctttt
   133561 tactgcaata ggtattcctc ttttaaacgt aataagtata aatgcaaata agccgtaaag
   133621 aattaataaa atagcacctc cacgccctcc tggtataaac acaataggga tatcaattat
   133681 tgtaaataga acatatatcc acttatgttt cactgaacct ttcataatga aataaatgcc
   133741 taatccggca gtaaatgctg aaaggtacga agcgttttga tagttcataa gtccaaaatt
   133801 gatatagcta ggtatctcac ctgtaagttt tggtattaaa attacaaaaa taaatgaaac
   133861 agaaaatatg aaaaatacta atttaaaaaa tctttctacc gtagccttgt ttatatattt
   133921 aatataaata ccactaattg ccgctggaac tgcccatgtt aaaaagaata gaatattatt
   133981 tttagctagt ttctcttcct tatctggtga aaaataataa aaagctagat aaagcaaaca
   134041 tatagcaatt aataatatta accctcgcgg aatttcttgc gtgacaatta tcttataaat
   134101 agcaaacacc gtagtaatta atgctatacc aaccatggtt gagtaataca ccggctctat
   134161 agggaaccct aatacttctt tagtaaatgt agagattact ataaatatgt tcatgctgat
   134221 aattgcacaa agtacaaaaa atttcatagt ttacctctct ttaaaattta tataatttta
   134281 ctaatcgttc actttctatt tgccaattca aaattttaga cgccttaatt gcattttgac
   134341 gtaaatgatt aaacaaatcg tgattatctc ttaattttct aaccgccttt tcaatttcta
   134401 acggcgtaac ttcctttaga acaatgccaa atttatattt ttcattgaga taaatatgct
   134461 ctttgacagg agataaaatt actggtaaac cagcatgtat acattcaaaa attttattag
   134521 atactgtata ttcaaaatta atagatacag gtttcgtcaa gacaacacca acattacttt
   134581 ctgctaactt atcaaccaat tcttttactt caactggttt atccaaccta atattttccg
   134641 ggttataact aatcagttct tttatcactt cttcatgcgg accaaaccct cgaattatga
   134701 atgaaggggc attttgttta aaagctgatg aagctataat aaactcttca tatcctctgt
   134761 ccattacaat ttgaccttga tatacgattg atttaaagtt ttcgatttct ttaaattctc
   134821 tgctatcatt taaaataggt gcattcgtaa taacattcgc ttccttctta tatcctttag
   134881 attgataata ttcttttgct gcatgactta ctgttacgaa ggcattaaca cgatgtttta
   134941 caatgtgttt ttctatactt tctacaaact ttgaaataag tggaacttta ttaataaagg
   135001 catttttcgc atatatttca tgcgcatcat aaacaatatt agctttttta taattgctta
   135061 aatagaccat taataatacg tcgaaatcat ttgcatgtat cacgtcaggt ttataagctt
   135121 taatttctcg gataacacct gttgcaaatc ttatacgctt aattaattta gaaagaatat
   135181 tttttggatc taccttgcta cctaacaaac gataattaca atctaaattt tccaatcgct
   135241 tattagtagc ttgtgaatta ttcattccaa caattttata atcattcgta acgcctttaa
   135301 ttgtttctat ttgtttaagt acccttgggt cttgaacaat attactcgat acaatattta
   135361 aaattctcat atcattaagt atccttttta tttaaatatt caaccgaaaa tccttttagt
   135421 ttgtcaggcg ttttctccca ccacttgctt tccaaaagtt tttcaattgt tttattgtca
   135481 aatcgcttct taatcacttt tgcaggaacc ccaccaacaa cctcatatgc tcctacattt
   135541 ttagtaacaa ctgagccggc tgctatgact gcaccagtat ttattgttaa tccatccata
   135601 ataattacat ttgcaccaat ccacacatca tttttaattg ttgtacggct tggttggtca
   135661 ttaaagtcta taaacttttg ctttatgtta aatggattat tattagaata aaaaatcggt
   135721 gatgagctaa aaaagtgtgt aggatgtttt cctaacccaa tttttacatc cgaagatatc
   135781 gaacaatatc ttcctacttc tacattatta aaatcactac caaatccaat ataactgtat
   135841 tcaccaatgt gagaattcct gattttacac catctatcta tatagttatt gccatcaaat
   135901 tttgagtttg taatatacgc caagcgatga atcttaacat tcgattcttt agaggactgg
   135961 tttttcagca aaccaattat cttttcaatc gctatcctca tcgtcatttc ctccaagtat
   136021 ttcgattgat aatatcttta tagctttgaa taattttaac tacctttgtc gaaacattag
   136081 tgtctttata atcaatagca tcaatcatcg gttcgttatt gttttgcatc tctcttgcta
   136141 gttcaacgga ttggattaga ttgttatagg taataccacc tacaataacc gtacctttat
   136201 ctagtacttc cggtctttct gtggaagttc gaataaggac accagggaac ttcaaaatag
   136261 acgactcttc tgacaatgtt ccactatctg atagcacaac aaatgcatct ttttgcaatg
   136321 cattataatc aaagaaacca aatggcttta actgtttaac tagtggatca aattcaaatt
   136381 tactttcttc aattttcttc caacttcttg gatgcgttga ataaatcaca ggcattttat
   136441 actttttggc aatatcattt atcgcattca ttaatgattt aaaattcttt tcattatcga
   136501 tattctcttc tctatgcgca gatactaaaa tgtattgttg cggttctaat cctagtttat
   136561 ttaaaacgtc actgtgatta attttatctc gatgcgcttc tatcacttct gtcatcggtg
   136621 atcctgtcac aaagatattc gctttattga agccttcatc taataaataa cgtctgctat
   136681 gttccgtata aggtagattc acatcactga catggtcaac aattttacga ttgatttctt
   136741 caggtacatt ctgatcaaag catctattac ccgcttccat gtggaataca ggaattttta
   136801 atcgtttagc agatactgct gctaaacaac tatttgtatc accaagaatt aaaagtgcat
   136861 ctggttgttc gcgtaataaa acgtcatatg tcttcgcaat aatattcccc atcgtttctc
   136921 caaggttact tccaactgcc tctaagtagt ggtccggttg tcttaattcc aaatcatcaa
   136981 agaaaatttg attcaatgta taatcataat tttgaccagt gtgtactaat atctgattaa
   137041 aatattgatc acatgcttta atcgttgatg ataaacgaat gatttcaggc cttgtaccaa
   137101 ctattgtcat taatttcagt ttttccatgc gctatacctc caagaaatac gtatctggct
   137161 gatttggatc aaacatttca ttcacccaca taatagttac catatctgtg tcgcctaaat
   137221 tttcaatatt atgtgtgtat cctactggta tgtctacaac ttctaatttg tcgccagaaa
   137281 cgtaatattc aatgatttca tcatcattaa catgtctaaa acgaattacc cctttacctg
   137341 atacgactag aaatttttcg tttttagtat gatgccagtg attaccttta gtaatacctg
   137401 gtttagaaat atttacagaa acttgaccac gatccggtgt ttttataaat tctgtaaaag
   137461 aacccctatc atccacattc ataagtaagg gataactaaa gtctgtacta ggtagatagc
   137521 ttaaatacgt actatacaaa tctttttcaa acaagttatc taatttcggc aatgttcgat
   137581 cgagacgtga ctgtttgaac ttgtataata aatctacaat ttctcccaat gtcactttaa
   137641 atacgtttgg tactgtaggt acaccatttt caatcgttgg agttccttca atagcacgtt
   137701 ttatttcagc gacgatatca tccacgtagt ttagcgtcag ttcaacattc cgatcattaa
   137761 cttgaatctc ttcgttacgt gcaattttgt aacaaaatgt tgcaatcact gagttataat
   137821 tcggcttaca ccacttaccg aataaatttg gccatcgata aatataaacc gtattgccat
   137881 actcttcgga atactctctt aatagctgtt ccccttgcaa cttactctca ccataaggat
   137941 tatcttgtgt tgcttgtatt gaagacgata ataatatcgc cggctttttc ttatttctag
   138001 ttaatatatc aagtacatga tctaaataac tcacgtttcc taagctgaat tctttgtcgt
   138061 gttcaggtcg attaacacct gctaaatgca cgacaaagtc tgctttcaac aacgctgact
   138121 ctaattcttc ctctttagtt tgtcgatgta cttcgaaaat atgataatct gtcgttgatg
   138181 ttaaatctgc tttcaagttt tttcctacaa aaccctttgc tcctgtaatt acaatattca
   138241 acgtcaatct ctcctatctc attgaagctt tataatcgtt caattcgttt ctaacatatt
   138301 ctagtgttaa aagtttttct tttatctctt ccaccgttaa aatatgtgta ttatcggagt
   138361 tatattcata agattgcgta atcttttcgt taccggtttc aacataatta ctataattta
   138421 aatctctgga gtctgccggc actctaaaat aatcacccat atcttcacat tgtgcgtatt
   138481 cttctctcgt caacaatgtt tctgcttttt tctctccatg tcgcgtacca atgatttcaa
   138541 ttgcattatc agcttcaaac aattctaata atgcggtcgc aagatcccct actgttgagc
   138601 ttggtgcttt ttgaaccatg atatcgcctg tctctgcatg cttaaatgca tgaacaacta
   138661 gttccacggc atcttctaaa ctcattaaaa atcttgtcat atcaggatct gtaatcgtta
   138721 aaggttctcc agctttgatt ttgtcgataa acaaaggaat tactgatcct cttgaagcca
   138781 tcacattacc gtatcttgta ccacaaataa gcgtttgttc actacgaata tttcttgatt
   138841 tggctatgaa tactttttcc atcattgctt tcgaaatacc catagcatta ataggatacg
   138901 ctgccttatc tgtagataaa catatgactt ttttaacatt ttgatgaata gcactttgta
   138961 agacattttc tgtaccaata atatttgtct tcactgcctc aactggaaag aattcacatg
   139021 acggcacttg ttttaaagct gctgcatgga atacgtaatc aacatctcgc attgctgttt
   139081 ctacactttg actatcacgc acatcaccaa tgtagaactt taattttgaa ttattatatt
   139141 tttttcgaat gtcatcttgt tttttctcat cgcgtgaaaa aatacgaatt tctttaatat
   139201 tagaatctaa aaaccgtttc ataacagcat taccgaatga tcctgtgccc ccagtaatta
   139261 ataaaatttt gtcatcgaac ataattatct ccctttttgc cattggcata gttaataatt
   139321 ttttctttac taaagtcatt gacgatgtct tgaataatgg cttcaacttc attacatttc
   139381 atatgttgta ctttgccacg ataaattttt tcaaatactt gttcaggatg aacttcatct
   139441 ttattcataa gctcttcaaa cattttttcg ccggatctaa tccctgtata agtaatgcgt
   139501 atgtcgtctt cttttttacc acttagctta attaaattac gtgccaaatc tacaattttc
   139561 actggttctc ccatatctag cacaaatact tcgccacctt ctgctaatgc ccctgcctgc
   139621 aaaactagtc tagaagcttc aggaattgtc ataaagtaac gtgtcatttc aggatgtgtc
   139681 acagtaactg gcccaccttc ttcaatttga cttttgaaaa gtggaatcac agaccctctc
   139741 gatccaagta cattaccaaa tctcactgca acaaaatttg tttgatgtgt ttcatcattt
   139801 aaactttgaa taatcatttc tgcaattcgc tttgaagctc ccatgacatt aggcggatta
   139861 acggctttat ccgtcgaaat cataacgaat ttctttacct ctgcattttt agcagcttca
   139921 gcagtatttt tcgtacctaa aatattatta cgtactgctt cttcagggtt gtcttccatt
   139981 aacggcacgt gcttgtgtgc tgctgcatga taaactgcgt atggtttata catttccaaa
   140041 atttcaaaca tacgcgctct attttgcaca tccgctataa taggaacgat atcaacattt
   140101 tttccgaagc gatttcgcaa ttcacgattg attaaataaa tactgttttc accatggcca
   140161 agtagaataa tacgttctgg atagaaatta caaacttgtc tacaaatttc tgatcctatt
   140221 gaaccacctg cacccgtaac taaaatagtt ttattcgtca attcatttga tatcatatcc
   140281 atatctaatt caacaggatc tctgcctagt aaatcttcta cttcaacttt tttaagttgg
   140341 ttcacttcta actcaccaga catgacgtct tctatatttg gcattttcaa taactcaacg
   140401 ccatccatat ggcaaatatt attaatttct ttcaaacgct cttgaccaat agttggaatt
   140461 gcaatgatga tttttttaat cttatatttc ctcactagtt ctggaatatc cgcaatttca
   140521 ccttggactt ttacaccctc agtaattgtg atattgcgtt tatgttcgtc atcatcgact
   140581 gctaataccg gttcaagttt catttcgtca cttttcaaca tttgtctaat cagcattgaa
   140641 cctgcttggc cagcaccaac aactaaagtt ggcttcttat taaatgactt acctccaagg
   140701 tatttccgat aaatacgcca aaataacctt gagccaccta ttaaaatcaa gtgcatcatc
   140761 caagtaatta aatacaatct aaaaaacggt ctattgcctg taacaattgt cacgaccacc
   140821 atcgtaataa cgatagatgt cgtcacagct ttaacaatta aaatcaattc actcacactg
   140881 gcatattccc acgctcgatg atacatatta aaaataaatg ctgaaatatg atgcgatatg
   140941 aatagtgata tagctgccaa tattaataat ttgacagaat atgttttgaa atacggttct
   141001 aaaatgtaat aacttacgaa tactgaaaat gtcactatca gtgaatcgat taatgctagt
   141061 attaaaagcc gcaatttcac agataaatgt gccataaaac ccctcatttg ctgtttataa
   141121 cccaaaccat cttttctgtt tataatcttg ttgtggcatt cgtttaggaa tttttttatc
   141181 atcaacaact aacttcgcat tactaataaa tccgttcata tcttcataat aatcacgtaa
   141241 tttcttatca ttaaataagt ctttcattaa gaacggtctg atttctgtgt tatgcgcatc
   141301 tgaaccgatg aaatgtgtca gattgttttc aatcatttga attgctaatt ttctaatttt
   141361 tttaccggaa atacccgcta atgacgccgt tgtcacttga cttaaagcac ctttgttaat
   141421 taaatcgtat agtatgtcaa ggttttgact tattgcttta ttccgctctg gatgtgcaat
   141481 aatcggtaca aagcctttac tttgtaattc gaaaaataat tgatcagtat agtgtggaac
   141541 ttcatttgat ggaaattcta ttagtaaata gcgtgaatca ttaataccgg taataacttt
   141601 tcgatcaata tcattaagga tttgatcggt aattcttatt tcctgaccat aataaaactt
   141661 tagattcagt gcttgtactt cctctaagct ttcaatatgg tttaaacatg atttcacttt
   141721 ttctataggt gtggtatatc gaggatgtaa gtgatgtgat gttacaatga tttctgtaac
   141781 accttgtgtt gtcgcttgtt ttaaaagatc tagcatctct gtttcatttg tcggaccgtc
   141841 atcgatatta ggcaatatat gattatgaat atcaatcata cttattcatc tccataatag
   141901 tgataataac tagaagattt atctactttt gccttattta aaatgacgcc cagaatgtta
   141961 ctgcctgctt tttccataag tattttagct tttttaactt catttttatc atttttttca
   142021 ctatcaatga ctaacagact atctttaata gcacgcgcat atagttgtgc atcagtcacg
   142081 gtattaactg gcggtgtatc gacaataata atgttgtaac gtttattgaa aagatcaact
   142141 aactctttaa atctttcaga accaattaat tctgttggat taggaggtac aggaccagct
   142201 gttagtaaat ctaaattatc aatttctgtc gtcgtaatag cttctgacat agtcgttcta
   142261 ccaatgatta aattcgataa tccattatta ttttgttcat taaaaatata gttttgtgtt
   142321 ggcttacgca tatccccatc gataattaac gttttataac ctgcttgtgc atacgtaatc
   142381 gctacattgg atacgactgt acttttacct gcaccaggtt tttcagaagt aactaataag
   142441 cgctttactt cgccatttgc ttttgaaaac atgatgtttg aacgtatacc ccgaaacttt
   142501 tcactaattg ttgattttgg tttttcatac acaaatagtg ttgttgtcgt attttccttt
   142561 tttgacataa gtagcaacca tccttaatta aatttttgaa ttgaacccaa tacaggcaat
   142621 cctaattctt tctctacatc ttcttcatct ttaattcgct tatcgaaaat tactttgaag
   142681 aagatatata taagcgcgac aactaatcct aaaaagaatg caccgattag attcactaca
   142741 gtttttggtg cgactttaac tgctgtaccg tctgctttag ataaaattga tacgttatct
   142801 acactcataa tcttcggaat ttgtttactt gtcactttgg caaagctatt cgcaattttt
   142861 tccgaatctt ccttatgacc acttttaact tggatgttga taagttgtgt attttcttga
   142921 ttcgtaattg tcaacatgct cgacaattta gatggtgaat acttatcatt taagtccttt
   142981 gacacttcat ctaaaattct aggactttta acaatttctt tatacgtatt tacaagttga
   143041 atattacttt gaacctcttg tgccataaac tgaggattgt cacccttagt ttgattcact
   143101 aagatttgag tattagcttg atatttaggt gataagacga aaaatgtaac aatagcgcta
   143161 attattaaaa ataatagcgg taaaataatt aaaattttca agtttttttg taatacttct
   143221 ttaatttttg ttaattctaa tgtactttcc attatttacc tcccttaaaa attttcatta
   143281 aaattggtat tatatatata tagtatttac atattacata tcatttaaac aattaattac
   143341 ttttaaatcg cattatttac gcatattcat ttatatgaaa ttaaaaataa ttatactcta
   143401 aagtagtaat agtttgtgaa atgagtatca atcttaatat tttctttatt
//
LOCUS       DAPSKH010000002       107713 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPSKH010000002 DAPSKH010000000
VERSION     DAPSKH010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 107713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 107713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..107713
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.002"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            98..1327
                     /locus_tag="RPH49_000117"
     CDS             98..1327
                     /locus_tag="RPH49_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDY5123317.1"
                     /translation="MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPC
                     KDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGIN
                     GMPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQ
                     HGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRG
                     AIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMA
                     DNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEAT
                     HINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIE
                     VDPQDVYDKTMKLTDLQ"
     gene            1522..2379
                     /locus_tag="RPH49_000118"
     CDS             1522..2379
                     /locus_tag="RPH49_000118"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDY5123318.1"
                     /translation="MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKE
                     LAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQ
                     QKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFI
                     LFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGD
                     INLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNDMRQTLSEI
                     LKIHQEVTK"
     gene            2379..3323
                     /locus_tag="RPH49_000119"
     CDS             2379..3323
                     /locus_tag="RPH49_000119"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit alpha"
                     /protein_id="HDY5123319.1"
                     /translation="MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERET
                     KKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLN
                     GRAVTVIGQQRGKDTKDNIYRNFGMSHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAY
                     PGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTY
                     SVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQA
                     LAIKSAFVEQLDSLESLSRDEIANDRFEKFRNIGSYIE"
     gene            3592..4560
                     /gene="pfkA"
                     /locus_tag="RPH49_000120"
     CDS             3592..4560
                     /gene="pfkA"
                     /locus_tag="RPH49_000120"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002462395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDY5123320.1"
                     /translation="MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGL
                     LNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGG
                     DGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTAS
                     SHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHS
                     IVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDL
                     LMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI"
     gene            4582..6339
                     /gene="pyk"
                     /locus_tag="RPH49_000121"
     CDS             4582..6339
                     /gene="pyk"
                     /locus_tag="RPH49_000121"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDY5123321.1"
                     /translation="MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHK
                     GRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPE
                     KFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNL
                     PGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFP
                     KIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITA
                     TQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSA
                     EAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYR
                     PHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVTNGDLI
                     IITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDK
                     VIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNM
                     LVTIDAAQGKIFEGYANVL"
     gene            complement(6689..8050)
                     /locus_tag="RPH49_000122"
     CDS             complement(6689..8050)
                     /locus_tag="RPH49_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5123322.1"
                     /translation="MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILL
                     TYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGM
                     AEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIG
                     LIVVGFVMILFAYKTQFGHASFTNLYEHGVFPKGASGFFMSFQMALFSFVGIEMIGVT
                     AGETKNPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGI
                     PFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFA
                     SSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKKA
                     TYKLFGGKYMGYLIFVFFIFVFGLLFINVETRRAIYFIPIWFILLGFMYLRYKRIAAK
                     SNN"
     gene            8398..9519
                     /locus_tag="RPH49_000123"
     CDS             8398..9519
                     /locus_tag="RPH49_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001662816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate synthase"
                     /protein_id="HDY5123323.1"
                     /translation="MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEE
                     VIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYI
                     AHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYM
                     LRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPL
                     HGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSR
                     QITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSR
                     SAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK"
     gene            9568..10836
                     /gene="icd"
                     /locus_tag="RPH49_000124"
     CDS             9568..10836
                     /gene="icd"
                     /locus_tag="RPH49_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDY5123324.1"
                     /translation="MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAA
                     VEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIR
                     SLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTT
                     EVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLV
                     HKGNIMKFTEGSFKQWGYDLALTEFGDQVFTWQQYDEIVEKEGRDAANSAQEKAEKEG
                     KIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYE
                     TGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASK
                     VVTYDFARLMDGAEEVSTSAFADELIKNLK"
     gene            11226..11930
                     /locus_tag="RPH49_000125"
     CDS             11226..11930
                     /locus_tag="RPH49_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5123325.1"
                     /translation="MSQKVLVVDDEHSIVTLLKYNLETAGYEVVVAFDGDEALEKVEN
                     EQPDLIILDVMLPKKDGIDVCKTVRTNKNLVPILMLTAKNDEFDRVLGLELGADDYMT
                     KPFSPREVVARVKAILRRSQFVKEVEEIDDDITIGSIRIRPDYFEVYKHNELLELTPK
                     EFELLLYLIERQGRVITREHMLNTVWNYEFAGDSRIVDVHISHLRDKLEDNPKEPQLI
                     KTVRGLGYKLERPKEQ"
     gene            11930..13591
                     /locus_tag="RPH49_000126"
     CDS             11930..13591
                     /locus_tag="RPH49_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAS domain S-box protein"
                     /protein_id="HDY5123326.1"
                     /translation="MKFHHRLMLLISSILIISFVTLGIIIHASITYVLSEKHEQALAT
                     DARSYIYLVQDNEIDKVKEIVKQQNIDLLITKNDKKVFSSGKLKATQNSDSYIQKKDV
                     FIFNKKVNGYHVWIKGYNNDITEMHWTLWKYLILTCLVVLICLYFASRSFKRTLIRPI
                     QEVTYATQLLANGYYHIRVPESNVIETKALFVSTNDLARRLQKLNNEQKMQSNRLKTT
                     IENIPSAILMIDRNGKIVVANKAYYEQFNISHNIEQVGYHGYVNTEIEQLILESFKVE
                     KPIYEQLEVAINQVHAKYFDISCVPILTRSQKSLQGILVVMHDITNLKQLENLRREFV
                     ANVSHELKTPITSIKGFAETLIDGAKNDAESLDMFLNIILKESNRIESLVTDLLDLSH
                     IEQHTELDTDYMNLSDLTRRIIDNMMTQANQKNISIHTDIEKDVIVKAQESKIAQVIT
                     NLLTNAINYSYEDGDINVRVYRDDFRVIFEVQDFGIGIKLEDQQRIFERFYRVDKARS
                     RDSGGTGLGLSITKHIVEAHQGNIEMNSQVGKGSTFKVILKDYKE"
     gene            14090..15577
                     /locus_tag="RPH49_000127"
     CDS             14090..15577
                     /locus_tag="RPH49_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123327.1"
                     /translation="MKTIQLHKTTLILIAILLFYTFMGILLPLMHDDLQWFSNYNTDI
                     LKVGFASLNGRYIGNIFEIIAVHVSWLRWLSYGLISMGIIWMIMHITRCKAWTSYYLL
                     AFSLMLILPSAIYADTYGWFAGFYNYATSTLISLFIIYYCINAIIYKEKQPVSVTVLF
                     YVLCFFGQLFMENVTLFHCIILILAFLYEFTANRTLNYKLLFSFMIATIGTIIMFSNP
                     NYRKILFEGSEYQQVSNNQGIFSKFAEMISTSLPYGVIFSQIIILSMIAALIIYLLLR
                     SDRYVHLTILKRRIIMIGFITLPLYYLLFYNQFLLNKNTDIGLVGFVNVIVCGYFAFS
                     IFVGIYLSINDRKTQITLYSLLIAICVSASTLVIVTPIEPGNFLIVYTIHVIILIILL
                     KEFRKYKSINVNFIKVASLVLAMIYLSAFIYVHYEHEKRVQLLKQQIKDHPRQEVYTV
                     ESLPFEHYMHHPSPINKNYQEWFNNYEELPKMTKVKYIPFGSDDS"
     gene            15871..18501
                     /gene="polA"
                     /locus_tag="RPH49_000128"
     CDS             15871..18501
                     /gene="polA"
                     /locus_tag="RPH49_000128"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDY5123328.1"
                     /translation="MNKLVLIDGNSLSFRAFYALPLLSNKAGIHTNAVYGFAMLLEKI
                     LKEEKPNHFLVAFDAGKTTFRHEKYSEYKGGRQKTPPELSEQFPYIRQLLDAYHIKRY
                     ELDNYEADDIIGTLSKEADKAGFQTIIITGDRDLTQLATDNVTIYYTKKGVTDVDHYT
                     PDFIAEKYNGLTPNQIIDMKGLMGDTSDNIPGVAGVGEKTAIKLLNQFDTVEGVYEHL
                     DEISGKKLKEKLQNSKEDALMSKELATINVDSPIEVKLEDTLMTHQDEQQEKIELFKK
                     LEFKQLLADIDQSASVEDAIEKTIEIETSFDNVDFTSLKEAAIHFELDGGNYLRNNIL
                     KFSLFTGEKHIVINADDINNYAELVSWLENPNTKKVVYDAKKTYVASHRLGIDIQNIS
                     FDIMLASYIIDPSRTISDVQSVVSLYGQSFVKDDVSIYGKGKKFKVPEDDVLNPYVAS
                     ITDAIYFAKPNMDKQLEEYNQVELLADLELPLAKILSEMEEIGIFTDVHDLEEMEKEI
                     QEKLDVLIRNIHDAAGEDFNINSPKQLGVVLFETLQLPVIKKTKTGYSTAVDVLEQLQ
                     GEHPIIDYILEYRQLSKLQSTYVEGLQKVISDDQRIHTRFNQTLAQTGRLSSVDPNLQ
                     NIPVRLEEGRKIRKAFKPTSKDSVILSADYSQIELRVLAHITQDESMKEAFINGDDIH
                     TATAMKVFGVEADQVDSLMRRQAKAVNFGIVYGISDYGLSQSLGITRKKAKAFIDDYL
                     ASFPGVKQYMSDIVKDAKALGYVETLLHRRRYIPDITSRNFNLRGFAERTAMNTPIQG
                     SAADIIKLAMVKFAQKMKETTYQAKLLLQVHDELIFEVPKSEVDSFSEFVEEIMENAL
                     QLDVPLKVDSSYGATWYDAK"
     gene            18517..19389
                     /gene="mutM"
                     /locus_tag="RPH49_000129"
     CDS             18517..19389
                     /gene="mutM"
                     /locus_tag="RPH49_000129"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDY5123329.1"
                     /translation="MPELPEVEHVKRGIEPYVINQKIEHVKFSDKVIEGKAQGKETII
                     KGIELDTFKTLSEGYTITNVERRSKYIVFQLDNKREQRTLISHLGMAGGFFIVDELED
                     IMIPNYRKHWHVIFELSNDKKLIYSDIRRFGEIRNVASVASYPSFLEIAPEPFSNEAL
                     TYYLNRIHQQSNKNKPIKQVILDHKVIAGCGNIYACEALFRAGVLPDKKVKDLTHQQQ
                     EMVFYYVREVLEEGIKYGGTSISDYRHADGKTGEMQLHLNVYKQPVCKVCGSQIETKI
                     IATRNSHYCPVCQK"
     gene            19405..20028
                     /locus_tag="RPH49_000130"
     CDS             19405..20028
                     /locus_tag="RPH49_000130"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDY5123330.1"
                     /translation="MPKVIGLTGGIASGKSTVSELLSVFGFKVVDADKAAREAVKKGS
                     KGLAQVREVFGDEAIDENGEMNRRYMGDLVFNHPEKRLELNAIIHPIVRDIMEEEKQE
                     YLKQGYNVIMDIPLLFENELENTVDEVWVVYTSESIQMDRLMQRNNLSLEDAKARVYS
                     QISIDKKSRMADHVIDNLGDKLELKQNLERLLEEEGYIEKPNYGEED"
     gene            20198..21223
                     /gene="gap"
                     /locus_tag="RPH49_000131"
     CDS             20198..21223
                     /gene="gap"
                     /locus_tag="RPH49_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDY5123331.1"
                     /translation="MSTNIAINGMGRIGRMVLRIALQNKNLNVVAINASYPPETIAHL
                     INYDTTHGKYNLKVEPIENGLQVGDHKIKLVADRNPENLPWKELDIDIAIDATGKFNH
                     GDKAIAHIKAGAKKVLLTGPSKGGHVQMVVKGVNDDQLDIEAFDIFSNASCTTNCIGP
                     VAKVLNNQFGIVNGLMTTVHAITNDQKNIDNPHKDLRRARSCNESIIPTSTGAAKALK
                     EVLPELEGKLHGMALRVPTKNVSLVDLVVDLEKEVTAEEVNQAFENAGLEGIIEVEHQ
                     PLVSVDFNTNPHSAIIDAKSTMVMSGNKVKVIAWYDNEWGYSNRVVDVAEQIGALLTS
                     KETVSAS"
     gene            21433..21903
                     /gene="nrdR"
                     /locus_tag="RPH49_000132"
     CDS             21433..21903
                     /gene="nrdR"
                     /locus_tag="RPH49_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDY5123332.1"
                     /translation="MKCPKCNSTQSKVVDSRHADELNAIRRRRECENCGTRFTTFEHI
                     EVSQLIVVKKDGTREQFSREKILNGLVRSCEKRPVRYQQLEDITNKVEWQLRDEGHTE
                     VSSRDIGEHVMNLLMHVDQVSYVRFASVYKEFKDVDQLLASMQGILSENKRSDA"
     gene            21904..23304
                     /locus_tag="RPH49_000133"
     CDS             21904..23304
                     /locus_tag="RPH49_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HDY5123333.1"
                     /translation="MGRQAFEFGLRPKDQFKVMQHFDLNTNHLEVLNRLYTPLIGTQA
                     VGLYHFMTQFVKESHNETLILSHYIFMNELKINLLEFRQQMDLLEAIGLLKAFVKHDE
                     QETQFVYQLIQPPSAHLFFNDPMLSIFLYSEVEHRRFHELKKYFEYQQIDLSEFKQVT
                     RQFTDVFKVPSTKIDIDTSDIPINEPYQGIDLSNESFDFEMLRQMLGKHFISQDIVTK
                     DAKRLITQLATLYGLTADGMKHVILNSITSGQQLSFEEMRKQARSYYLMEHENQMPKL
                     QVKSPVTSSSTGKSSEVNPKPQSDEWFELLEQTSPIDMLASWSESEPTISQKTMVEEL
                     IEREKMSFGVINILLQFVMLKEDMKLPKAYILEIASNWKKKGIKTAKEAYNYAKKVNQ
                     PKNEGSSGNYQKRGSYYGQRNRISKEKTPKWLENRDKPSEEDSAKDNSVDDQQLEQDR
                     QAFLDKLSKKWEEDSQ"
     gene            23304..24224
                     /gene="dnaI"
                     /locus_tag="RPH49_000134"
     CDS             23304..24224
                     /gene="dnaI"
                     /locus_tag="RPH49_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDY5123334.1"
                     /translation="MKQFKSIINTSQDFEKRIEKIKKEVINDPDVKQFLEAHRAELTN
                     AMIDEDLNVLQEYKDQQKHYDGHKFADCPNFVKGHVPELYVDNNRIKIRYLQCPCKIK
                     YDEERFEAELITSHHMQRDTLNAKLKDIYMNHRDRLDVAMAADDICTAITNGEQVKGL
                     YLYGPFGTGKSFILGAIANQLKSKKVRSTIIYLPEFIRTLKGGFKDGSFEKKLHRVRE
                     ANILMLDDIGAEEVTPWVRDEVIGPLLHYRMVHELPTFFSSNFDYSELEHHLAMTRDG
                     EEKTKAARIIERVKSLSTPYFLSGENFRNN"
     gene            24317..24439
                     /locus_tag="RPH49_000135"
     CDS             24317..24439
                     /locus_tag="RPH49_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123335.1"
                     /translation="MFDENMVNKLGDYYFIYGICNEYPDQDRYLKQRYLIHKLY"
     gene            24637..26574
                     /gene="thrS"
                     /locus_tag="RPH49_000136"
     CDS             24637..26574
                     /gene="thrS"
                     /locus_tag="RPH49_000136"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDY5123336.1"
                     /translation="MEQINIQFPDGNKKAFDKGTTTEDIAQSISPGLRKKAVAGKFNG
                     QLVDLTKPLETDGSIEIVTPGSEEALEVLRHSTAHLMAHAIKRLYGNVKFGVGPVIEG
                     GFYYDFDIDQNISSDDFEQIEKTMKQIVNENMKIERKVVSRDEAKELFSNDEYKLELI
                     DAIPEDENVTLYSQGDFTDLCRGVHVPSTAKIKEFKLLSTAGAYWRGDSNNKMLQRIY
                     GTAFFDKKELKAHLQMLEERKERDHRKIGKELELFTNSQLVGAGLPLWLPNGATIRRE
                     IERYIVDKEVSMGYDHVYTPVLANVDLYKTSGHWDHYQEDMFPPMQLDETESMVLRPM
                     NCPHHMMIYANKPHSYRELPIRIAELGTMHRYEASGAVSGLQRVRGMTLNDSHIFVRP
                     DQIKEEFKRVVNMIIDVYKDFGFEDYSFRLSYRDPEDKEKYFDDDDMWNKAENMLKEA
                     ADELGLSYEEAIGEAAFYGPKLDVQVKTAMGKEETLSTAQLDFLLPERFDLTYIGQDG
                     EHHRPVVIHRGVVSTMERFVAFLTEETKGAFPTWLAPKQVQIIPVNVDLHYDYARQLQ
                     DELKSQGVRVSIDDRNEKMGYKIREAQMQKIPYQIVVGDKEVENNQVNVRQYGSQDQE
                     TVEKDEFIWNLVDEIRLKKHR"
     gene            27000..28493
                     /locus_tag="RPH49_000137"
     CDS             27000..28493
                     /locus_tag="RPH49_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5123337.1"
                     /translation="MSKVQNESNNVVKRGLKDRHISMIAIGGCIGTGLFVTSGGAIHD
                     AGALGALIGYAIIGIMVFFLMTSLGEMATYLPVSGSFSTYATRFVDPSLGFALGWNYW
                     FNWVVTVAADITIAAQVIQYWTPLQGIPAWAWSALFLVIIFSLNSLSVRVYGESEYWL
                     ALIKVVTVIVFIAIGLLTIVGIMGGHVVGFEIFNKGEGPILGGNLGGSLLSILGVFLI
                     AGFSFQGTELIGITAGESENPERAVPKAIKQVFWRILLFYILAIFVIGMLIPYDSSAL
                     MGGSDNVATSPFTLVFKNAGFAFAASFMNAVILTSVLSAGNSGMYASTRMLYSMSKDK
                     LAFEAFGKTNKNGVPYMSLLVTAIIVVIIFVLQSLTKGAYEYIVAASGLTGFIAWVGI
                     AVSHYRFRRAFDKQNYDKSKLKYTAKLFPFGPLFAGFLCIVVIIGQDVDFIKTGDFNF
                     SRFLITYMGIPVFLAFFIYHKLRYKTKKIPLEQVDLRQDVSMDEIKG"
     misc_feature    28568..28693
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            28722..29249
                     /gene="infC"
                     /locus_tag="RPH49_000138"
     CDS             28722..29249
                     /gene="infC"
                     /locus_tag="RPH49_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDY5123338.1"
                     /translation="MSTIAKDQTQINDKIRAKELRLIGQDGEQIGVKSKREALEMAER
                     VDLDLVVVAPNAKPPVARIMDYGKFKFEQQKKEKEMKKKQKIINVKEIRLSPTIEEHD
                     FQTKLKNGRKFLTKGDKCKVSIRFRGRAITHKEIGQRVLEKYADECKDIATVEQKPKM
                     DGRQMFIMLAPTAEK"
     gene            29278..29478
                     /gene="rpmI"
                     /locus_tag="RPH49_000139"
     CDS             29278..29478
                     /gene="rpmI"
                     /locus_tag="RPH49_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDY5123339.1"
                     /translation="MPKMKTHRGAAKRVKRTASGQLKRSRAFTSHLFANKSTKQKRQL
                     RKARLVSKSDMKRVKQLLAYKK"
     gene            29525..29881
                     /gene="rplT"
                     /locus_tag="RPH49_000140"
     CDS             29525..29881
                     /gene="rplT"
                     /locus_tag="RPH49_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDY5123340.1"
                     /translation="MPRVKGGTVTRARRKKTIKLAKGYFGSKHTLYKVAKQQVMKSGQ
                     YAFRDRRQRKRDFRKLWITRINAAARQHEMSYSRLMNGLKKAGIDINRKMLSEIAISD
                     EKAFAQLVTKAKDALK"
     gene            30023..30631
                     /locus_tag="RPH49_000141"
     CDS             30023..30631
                     /locus_tag="RPH49_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDY5123341.1"
                     /translation="MSKFDEQIIVVPREIIFNNEKNTFNGFLNKNKPEGQNIFDALSQ
                     YEVKRRGDMEEDPSYKQLISYCLLENEHGEILVYERLSGGGEARLHGQSSIGVGGHMN
                     DVPGAESINEVLRVNAQRELEEEVGLSEQDSQNMEYIGFINDDNNEVGKVHIGVVFKI
                     TVSTNDVEAKETDTLRIKWVEKGNIESYDDFETWSALILQDL"
     gene            30650..31579
                     /locus_tag="RPH49_000142"
     CDS             30650..31579
                     /locus_tag="RPH49_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123342.1"
                     /translation="MSDIIQFPNSSIKLYKDIKRAEQDQNYDLMYEYIVQYERQFELT
                     EEIAMMKCRMLYETGSFLELREETIVLLKTGIQQYDALMIYYVKSLIGLGQYFEAVEV
                     IHQIIDEVKDHKTRMALHPLKEFAKSKLIEDEKRLTQSLTDFDTLSMREQTHLILKLI
                     DIGHFQFQETVLYILKSNTYSYNLISLMIEYLRFANCTQELTIEKYGMDVTFVPANLN
                     GLEHTTLKEKVIPNVMETLNDGALHIAEEAHHIMNNHSIMIYPIDIETLFETNKWINA
                     YECYFKNMLGLKCELQSIDAFNFIQQLDLNNNS"
     gene            31584..31694
                     /locus_tag="RPH49_000143"
     CDS             31584..31694
                     /locus_tag="RPH49_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123343.1"
                     /translation="MQNNTQHFNIVLTKKVDLQIYKRCDFNVCIGNRPMI"
     gene            31742..33043
                     /locus_tag="RPH49_000144"
     CDS             31742..33043
                     /locus_tag="RPH49_000144"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDY5123344.1"
                     /translation="MTATWEKKEGNEGLLTVTVPAEKVNKALDQAFKKVVKQINVPGF
                     RKGKVPRPIFEQRFGVEALYQDAIDILLPDAYGEAIDETDIKPVAQPEVSVTQIEKGK
                     DFIFEATVTVEPEVKLGDYKGLEIEKQETELSDDELQEAIDHSLGHLAEMVVKEDGVV
                     ENGDTVNIDFSGSVDGEEFEGGQAEGYDLEIGSGSFIPGFEEQLEGMKVDEEKDVVVT
                     FPEEYHAEELAGKEATFKTKVNEIKFKEVPELTDEIANELDAEANTVDEYKENLRKRL
                     AEQKATDAENVEKEEAITKATDNTTIDIPEAMVNTELDRMVSEFAQRIQQQGLDLQTY
                     FQISGQDESQLREQMKDDAEQRVKTNLTLTAIAEAEKIEATDEDIDKELEKMSKQFNI
                     SVEDIKNTLGNTDIIKNDVRIQKVIDLLRDNAKFVEGTKED"
     gene            33194..34456
                     /gene="clpX"
                     /locus_tag="RPH49_000145"
     CDS             33194..34456
                     /gene="clpX"
                     /locus_tag="RPH49_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDY5123345.1"
                     /translation="MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSE
                     IVEEELAQNTSEAITELPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPK
                     EDDVELQKSNIALIGPTGSGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENIL
                     LRLIQAADFDIDKAEKGIIYVDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTA
                     SVPPQGGRKHPNQEMIQIDTTNILFILGGAFDGIEEVIKRRLGEKVIGFSSNEADKYD
                     EQALLAQIRPEDLQAYGLIPEFIGRVPIVANLETLDVTALKNILTQPKNALVKQYTKM
                     LELDDVDLEFTEEALSAISEKAIERKTGARGLRSIIEESLIDIMFDVPSNENVTKVVI
                     TAQTINEETEPELYDAEGNLINNSKTSA"
     gene            34610..35200
                     /locus_tag="RPH49_000146"
     CDS             34610..35200
                     /locus_tag="RPH49_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDY5123346.1"
                     /translation="MKVNPNNIELIISAVKEEQYPETELSEVALSGRSNVGKSTFINS
                     MIGRKNMARTSQQPGKTQTLNFYNIDEQLIFVDVPGYGYAKVSKTQREKFGKMIEEYI
                     TKRENLQLVIQLVDLRHDPTQDDILMYNYLKHFDIPTLVICTKEDKIPKGKVQKHIKN
                     IKTQLDMDPDDTIVSYSSIKNNKQQQIWNLIEPYIS"
     gene            35417..36763
                     /locus_tag="RPH49_000147"
     CDS             35417..36763
                     /locus_tag="RPH49_000147"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDY5123347.1"
                     /translation="MHFIAISINHRTADVALREQVAFRDDALRIAHEDLYETKSILEN
                     VILSTCNRTEVYAVVDQIHTGRYYIQRFLARAFGFEVDDIKAMSEVKVGDEAVEHLLR
                     VTSGLDSIVLGETQILGQIRDAFFLAQSTGTTGTIFNHLFKQAITFAKRAHNETDIAD
                     NAVSVSYAAVELAKKVFGKLKSKQAIIIGAGEMSELSLLNLLGSGITDITVVNRTIEN
                     AMKLAAKHQVKYDELSSLPNLLESADIVISSTSAQSYIITNEMIERIAENRKQDSLVL
                     IDIAVPRDIEPGISAITNIFNYDVDDLKGLVDANLRERQLAAATISEQIPAEIHAHNE
                     WISMLGVVPVIRALREKAMTIQAETMDSIDRKLPGLSERERKIISKHTKSIINQMLKD
                     PIKQAKELSSDKKSNEKLELFQNIFDIEAECPHEQAKQQKESKVKEISARRIFSFE"
     gene            36785..37600
                     /gene="ccsA"
                     /locus_tag="RPH49_000148"
     CDS             36785..37600
                     /gene="ccsA"
                     /locus_tag="RPH49_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis protein CcsA"
                     /protein_id="HDY5123348.1"
                     /translation="MQENLFIRFNEIILLIYLISIICYFYDFVQKSHKIRSLGIYLLG
                     IVWVLQTISLSIFIIQTRHIPLGSISDVFYTLSWLIISISLILNLIKVLNFSVFFLNL
                     IGLTLLGMNTFQPTHYTNKVQKIAVVDELLLVHIGLAVLSYVFFALAFVNALLYIMQY
                     RNLKEKRFDQKYFRIGSVATLESIVFYSTLSGWIILIFSIILGTQWGVISVGERIFID
                     PKVILSSIITVLYGSYILLRINKWLNSRYLIYYNIILFCLNMINLFFATHFVN"
     gene            37642..38568
                     /gene="hemC"
                     /locus_tag="RPH49_000149"
     CDS             37642..38568
                     /gene="hemC"
                     /locus_tag="RPH49_000149"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDY5123349.1"
                     /translation="MRKLVVGSRRSKLALTQSQQFIDKLKAVEPNLEIEIKEIVTKGD
                     RIVDKQLSKVGGKGLFVKEIQHELFEKNIDMAIHSLKDVPSVIPEGLTLGCIPDRELP
                     FDAYISKTHTPLSQLPEGSIIGTSSLRRGAQILSKYPNLEIKWIRGNIDTRLEKLQTE
                     DYDAIILAAAGLRRMGWSDDIVTSYLDRDTLLPAIGQGALGIECRSDDEELLTLLSKV
                     HNDEVAKCVTAERTFLAEMDGSCQVPIAGYATISDQKEIEFTGLIMTPDGKERFEYTM
                     NGTDPVELGKTVSNKLKEQGAYEIIKRLNEQH"
     gene            38590..39258
                     /locus_tag="RPH49_000150"
     CDS             38590..39258
                     /locus_tag="RPH49_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDY5123350.1"
                     /translation="MKPVVVMTQTNDMQSDLVSIIHKPFIDIKPLNFDIHLLNQRYDW
                     LVFSSKNAVKFFYKYLKGINVDNIAVIGSKTAQYCESLGIRVDFMPNDFSQEGFLKSF
                     NQTNQKILLPSSELARPLLLAALSKNNEVVKIDLYTSVPNKQNIQDVKEMIEHQQIDA
                     LTFSSSSAVRYYFNEGFVPKFKSYFAIGEQTARTIKSYQQPVTIAEIQTLESLIEKIL
                     ESRG"
     gene            39261..40235
                     /gene="hemB"
                     /locus_tag="RPH49_000151"
     CDS             39261..40235
                     /gene="hemB"
                     /locus_tag="RPH49_000151"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001633925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDY5123351.1"
                     /translation="MKFDRHRRLRSSATMRDMVRENHVRKEDLIYPIFVVEKDDVKKE
                     IKSLPGVYQISLNLLESELKEAYDLGIRAIMFFGVPNSKDDIGTGAYIHDGVIQQATR
                     IAKKMYDDLLIVADTCLCEYTDHGHCGVIDDHTHDVDNDKSLPLLVKTAISQVEAGAD
                     IIAPSNMMDGFVAEIRRGLDEAGYYNIPIMSYGVKYASSFFGPFRDAADSAPSFGDRK
                     TYQMDPANRLEALRELESDLKEGCDMMIVKPALSYLDIVRDVKNHTNVPVVAYNVSGE
                     YSMTKAAAQNGWIDEERVVMEQMVSMKRAGADMIITYFAKDICRYLDK"
     gene            40283..41569
                     /gene="hemL"
                     /locus_tag="RPH49_000152"
     CDS             40283..41569
                     /gene="hemL"
                     /locus_tag="RPH49_000152"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDY5123352.1"
                     /translation="MRYTKSEEAMKVAETLMPGGVNSPVRAFKSVDTPAIFMDHGKGS
                     KIYDIDGNEYIDYVLSWGPLILGHRDPQVISHLHEAIDKGTSFGASTLLENKLAQLVI
                     DRVPSIEKVRMVSSGTEATLDTLRLARGYTGRNKIVKFEGCYHGHSDSLLIKAGSGVA
                     TLGLPDSPGVPEGIAKNTITVPYNDLDALKIAFEKFGDDIAGVIVEPVAGNMGVVPPI
                     EGFLQGLRDITTEYGALLIFDEVMTGFRVGYHCAQGHFGVTPDLTCLGKVIGGGLPVG
                     AFGGKKEIMDHIAPLGNIYQAGTLSGNPLAMTSGYETLSQLTPETYEYFNMLGDILED
                     GLKRVFAKHNVPITVNRAGSMIGYFLNEGPVTNFEQANKSDLKLFAEMYREMAKEGVF
                     LPPSQFEGTFLSTAHTKEDIEKTIQAFDTALSRIVK"
     gene            41630..41731
                     /locus_tag="RPH49_000153"
     CDS             41630..41731
                     /locus_tag="RPH49_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123353.1"
                     /translation="MGGDLIVKVHICFVVKTASGYCYLNKREAQAAI"
     gene            41765..42838
                     /locus_tag="RPH49_000154"
     CDS             41765..42838
                     /locus_tag="RPH49_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDY5123354.1"
                     /translation="MTMIYRNNFIVFVLSFFISIILYSSHVLLPFMFGPIIASIICVK
                     VFKLDIKWPFLLSELGIVLLGVQIGSTFTKNVVMDIKDNWLSIIVVSISILLIALVMA
                     FIFKKIARINTETAILSVIPGALTQMLVMAEQDKRANLLVVSLTQTSRIIFVVVLVPF
                     ISYFFHDGNMHANGKLTKVLPLSQVLNIGQIVILAIAIFIVYLIMSKIKFPTFQLLAP
                     LIVLIVWNFSTDLTFTLDHWLLNMAQLIYMIRIGVQIAHLLSDLKGRLAIAITIQNIM
                     LIIGALIMVYVIHFFDNNPINELFLGAAPGGVNQIVLVALATGADVAMITSYHIFRIF
                     FILFIIAPGINYFLKYRSNKRED"
     gene            complement(43061..43621)
                     /locus_tag="RPH49_000155"
     CDS             complement(43061..43621)
                     /locus_tag="RPH49_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDY5123355.1"
                     /translation="MNDCAFGTKDPVYLDYHDYVWGQPLYDSKALFKLLALESQHAGL
                     SWLTILKKKEAYEEAFYDFEPEKVAQMTAQDIDRLMTFPNIVHHRKKLEAIVNQAQGY
                     LKIEQAYGSFSKFLWSYVNGKPKDLQYEHASDRITVDDTATQLSKDLKQYGFKFLGPV
                     TVFSFLEAAGLYDAHLKDCPSKPKHN"
     misc_binding    43679..43980
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            44025..46655
                     /locus_tag="RPH49_000156"
     CDS             44025..46655
                     /locus_tag="RPH49_000156"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDY5123356.1"
                     /translation="MEMKPKYDPREVEAGRYEEWVKNGYFKPSEDKSKETYTIVIPPP
                     NVTGKLHLGHAWDTTLQDIITRMKRMQGYDTLYLPGMDHAGIATQAKVEAKLNEQGIT
                     RYDLGREKFLEQAWDWKEEYASFIRAQWAKLGLGLDYSRERFTLDEGLSKAVKKVFVD
                     LYNKGIIYRGERIINWDPKARTALSDIEVIHEDVQGAFYHFKYPYADGEGFIEIATTR
                     PETMLGDTAIVVNPNDERYKDVIGKTVILPIVGRELPILADEYVDIDFGSGAMKVTPA
                     HDPNDFEIGQRHQLENIIVMDENGKMNDKAGKYEGMDRFDCRKQLVEDLKEQDLVIKI
                     EDHVHSVGHSERSGAVVEPYLSTQWFVRMEDLAKRSLDNQKTDDRIDFYPQRFEHTFN
                     QWMENIRDWTISRQLWWGHQIPAWYHKETGEIYVGEEAPTDIENWQQDEDVLDTWFSS
                     ALWPFSTLGWPDLESEDFKRYYPTNALVTGYDIIFFWVARMIFQGLEFTDRRPFNDVL
                     LHGLVRAEDGRKMSKSLGNGVDPMDVIDEYGADSLRYFLATGSSPGHDLRYSTEKVES
                     VWNFINKIWNGARFSLMNIGEDFKVEDIDLSGNLSLADKWILTRLNETIATVTDLSDK
                     YEFGEVGRALYNFIWDDFCDWYIEMSKIPMNGNDEEQKQVTRSVLSYTLDNIMRMLHP
                     FMPFVTEKIWQSLPHEGDTIVKASWPEVRESLIFEESKQTMQQLVEIIKSVRQSRVEV
                     NTPLSKEIPILIQAKDKEIETTLSQNKDYLIKFCNPSTLNISTDVEIPEKAMTSVVIA
                     GKVVLPLEGLIDMDKEISRLEKELAKLQSELDRVDKKLSNENFVSKAPEKVINEEKRK
                     KQDYQEKYDGVKARIEQLKA"
     gene            46668..47939
                     /locus_tag="RPH49_000157"
     CDS             46668..47939
                     /locus_tag="RPH49_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDY5123357.1"
                     /translation="MNYLESLYWIHERTKFGIKPGVKRMEWMLAQFNNPQNNIKGIHV
                     GGTNGKGSTVAYLRTALVENGYEVGTFTSPFIETFNERISLNGVPISNDAIVELVSRI
                     KPVSEMMERETDLGVATEFEIITAMMFLYFGEIHPVDFVIVEAGLGIKNDSTNVFTPV
                     LSILTSIGLDHTDILGGTYLDIARDKGAIIKPNVPVIYAVKNEDALKYVRERAIEQHA
                     KPIELDREIVVVSQNDEFTYRYKDYELETIILSMLGEHQKQNAALAITALIELNEQGL
                     IELDFNKMIDGIESVRWTGRIEQVHDKPLIILDGAHNSESIDALIDTIKQYHDKEKVD
                     ILFSAINGKPINEMVKHLSLIAHTFYATEFDFPKALRKEEIVGSIENDEIQLVDDYVE
                     FIKNYQGDTLVITGSLYFISEVKSKLDFEAL"
     gene            48209..48916
                     /locus_tag="RPH49_000158"
     CDS             48209..48916
                     /locus_tag="RPH49_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDY5123358.1"
                     /translation="MVVLLSYSCSCIFSFLYQFISIEETSFDYLHRRSKCDYCNSSLK
                     WYELMPIISFLLLKGRCRNCRKRISLTHFLGETFAIIPIVFIKYDFTYVNATLFITTY
                     VFLLIFTMTDITSLMLDCRLIIIYCIVSLSLSMIYPVAFIIISMTTHIFYFLFRAYIG
                     YGDVLLISALSLFFPLQFTIYVILFTFVIAGLVALITMIFKPIKLLPLVPFIFISFFI
                     NSLFYNDIHQFLGGVYF"
     gene            48913..49599
                     /gene="radC"
                     /locus_tag="RPH49_000159"
     CDS             48913..49599
                     /gene="radC"
                     /locus_tag="RPH49_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDY5123359.1"
                     /translation="MKIKEMVTSEMPRERLLSHGAKSLSNTELLAILINTGRKGFSSI
                     DISNELLKSASNLNELKKSSINDLIQVKGIGLQKAITLKAAFELGERMGRRAENNRIK
                     ITQPSDVADYMIPTMKDLTQEHFVILLLNSKNVVIKETCVFKGTLNSSIVHPREIFSI
                     AVRENANAIIAVHNHPSGDVTPSQEDIITTMRLKECGLILGIDLLDHIIIGDNRFTSL
                     VEAGYFDEND"
     gene            49667..49951
                     /locus_tag="RPH49_000160"
     CDS             49667..49951
                     /locus_tag="RPH49_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123360.1"
                     /translation="MTLFIIIGVLVPMVYTMQLNIKNEPVTKRNLLITLALSTLGILV
                     TALAGVIVTKQAFPLLSVAIGSIFTGIVWGLLLSGSYALIRFLSNAFGRK"
     gene            complement(50068..50265)
                     /locus_tag="RPH49_000161"
     CDS             complement(50068..50265)
                     /locus_tag="RPH49_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123361.1"
                     /translation="MSILTIILIALLVILLFRVGLSILRFLIYVGLVLLCIYLGYQGL
                     IWLLDFFQINSGFLPHFQFNN"
     gene            50425..50898
                     /locus_tag="RPH49_000162"
     CDS             50425..50898
                     /locus_tag="RPH49_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4930 family protein"
                     /protein_id="HDY5123362.1"
                     /translation="MRLIFSMIKNIIAVIAIVIIVYIALKYAPFLKEQDWNPVNHDND
                     QMNQVTQPTNDAQHVYVSGEKYSLKENDLIKNVPLSQIKNVFKMIDKQEFMAVSGMNR
                     MAYNDQYIIGQRGDEFILYKFGDESMRVYNTEFEMQQDLNELGQNLQLKPENAYQ"
     gene            50972..51091
                     /locus_tag="RPH49_000163"
     CDS             50972..51091
                     /locus_tag="RPH49_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123363.1"
                     /translation="MAEQSKQKQANEQQKAQNLFARWRQLQNSNSESSNDTNK"
     gene            51291..52133
                     /gene="mreC"
                     /locus_tag="RPH49_000164"
     CDS             51291..52133
                     /gene="mreC"
                     /locus_tag="RPH49_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDY5123364.1"
                     /translation="MLKFFKNNKLIVVLCAIIVFIALIGLSIRSQSQSPPEQYIGDSV
                     SFGQRVVSYPVNFVAGTIGDFFKKGDSKESKNKISQLESKNQQLEAENEKLKKELDLK
                     DISKFDPISTTVLARNPDQWMNTIVIDKGSKSGITSNMAVMTSKGFVGRVTKVNKFSS
                     QVDLISTNTRAGKLSVNIQHGSKNIFGLIDRYDEKNSELVISDINNRDNISKGDKVVT
                     SGLADQLPSNLYIGEVTKVQNDQYGLAKEVRVKTGADLTDLSHVYVAKRDPKTIPDDE
                     SRDK"
     gene            52133..52663
                     /gene="mreD"
                     /locus_tag="RPH49_000165"
     CDS             52133..52663
                     /gene="mreD"
                     /locus_tag="RPH49_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDY5123365.1"
                     /translation="MRTLYYFLIGILLFYIDTAIGLLIPMNIGKFELVFVPHLTFMYI
                     LMMVVYRGFGVSLLLSIFLGVMTDVYFGSIYGVYLFGYILFLALIDRFFKIFYKDHSM
                     LFIIILASTLLLEVYVALIYGMLGFIQFDIIHFVVFRLLPTLIMNFVLLIMLYPLIIK
                     FLKKTNNDIDMKRRQW"
     misc_feature    52690..52886
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            52899..53207
                     /gene="rplU"
                     /locus_tag="RPH49_000166"
     CDS             52899..53207
                     /gene="rplU"
                     /locus_tag="RPH49_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDY5123366.1"
                     /translation="MFAIIETGGKQIKVEEGQEIFVEKLDVNEGDTFTFDKVLFVGGD
                     SVKVGAPTVEGATVTATVNKQGRGKKITVFTYKRRKNSKRKKGHRQPYTKLTIDKINA
                     "
     gene            53213..53533
                     /locus_tag="RPH49_000167"
     CDS             53213..53533
                     /locus_tag="RPH49_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDY5123367.1"
                     /translation="MITVDITVNDEGKVTDVIMDGHADHGEYGHDIVCAGASAVLFGS
                     VNAIIGLTSERPDINYDDNGGHFHIRSVDTNNDEAQLILQTMLVSLQTIEEEYNENIR
                     LNYK"
     gene            53545..53829
                     /gene="rpmA"
                     /locus_tag="RPH49_000168"
     CDS             53545..53829
                     /gene="rpmA"
                     /locus_tag="RPH49_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009382703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDY5123368.1"
                     /translation="MLKLNLQFFASKKGVSSTKNGRDSESKRLGAKRADGQFVTGGSI
                     LYRQRGTKIYPGENVGRGGDDTLFAKIDGVVKFERKGRDKKQVSVYAVAE"
     gene            54049..55341
                     /gene="obgE"
                     /locus_tag="RPH49_000169"
     CDS             54049..55341
                     /gene="obgE"
                     /locus_tag="RPH49_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDY5123369.1"
                     /translation="MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASV
                     VFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDE
                     VLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
                     VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIE
                     GASDGVGLGHQFLRHVERTKVIVHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRP
                     QIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDV
                     DFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAV
                     RRFARQMRSMGIDDALRERGCKNGDIVRILGGEFEFVE"
     gene            55354..55809
                     /locus_tag="RPH49_000170"
     CDS             55354..55809
                     /locus_tag="RPH49_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDY5123370.1"
                     /translation="MDNKDYKKFYLIREDVLPESVVKTLKIKDALKSDPTLSIYDAVK
                     QFDLSRSAFYKYRETIFPVDDKMLDHREFTLILYVTDIVGMLARVLDVISKLELSVLT
                     IHQSIPMEEKATITLSLNAKSKETAVEDVIGALRNLDYVSKVELISMSM"
     gene            55823..56425
                     /gene="ruvA"
                     /locus_tag="RPH49_000171"
     CDS             55823..56425
                     /gene="ruvA"
                     /locus_tag="RPH49_000171"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDY5123371.1"
                     /translation="MYAYVKGKLTHLYPTHVVVETAGVGYEIQTPNSYRFQKQLDHEV
                     LIHTSLIVREDAQLLYGFSSEEEKDMFLSLIKVTGIGPKSALAILATSTPNEVKRAIE
                     NENDTYLTKFPGIGKKTARQIVLDLKGKVKITEEDSDSLLQVDATSTVQDQFVQEAML
                     ALEALGYSKRELAKVEKTLNKNKYDSVDEAVKAGLQLVVS"
     gene            56457..57461
                     /gene="ruvB"
                     /locus_tag="RPH49_000172"
     CDS             56457..57461
                     /gene="ruvB"
                     /locus_tag="RPH49_000172"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDY5123372.1"
                     /translation="MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIK
                     AAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGL
                     QPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATT
                     RAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTP
                     RVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNG
                     GPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERE
                     "
     gene            57463..58488
                     /gene="queA"
                     /locus_tag="RPH49_000173"
     CDS             57463..58488
                     /gene="queA"
                     /locus_tag="RPH49_000173"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDY5123373.1"
                     /translation="MNFEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFK
                     DIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRI
                     KVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDD
                     PDRYQTVYAKESGSAAAPTAGLHFTDELLTEIKNKGVNIAFVTLHVGLGTFRPVSVDD
                     VNDHEMHSEYYQMTQETADLLNDTESKGHRIISVGTTSTRTLETIRRDHDKFVETSGW
                     TNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSTRENVLNAYKTAVNLEYRFFSF
                     GDAMLII"
     gene            58511..59650
                     /gene="tgt"
                     /locus_tag="RPH49_000174"
     CDS             58511..59650
                     /gene="tgt"
                     /locus_tag="RPH49_000174"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016425271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDY5123374.1"
                     /translation="MPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVK
                     TMSPEELRQIEAKIILGNTYHLWLQPGNDIIKHAGGLHKFMNWDGPILTDSGGFQVFS
                     LSNLRKITEEGVEFRHHTNGSKLFLSPEKSMQIQNDLGSDIMMAFDECPPMPAEYDYV
                     KKSIERTTRWAKRCLDAHQRPEDQALFGIIQGGEYEDLREQSAKDLVELDFPGYAIGG
                     LSVGEPKPVMYKMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIA
                     RNGTCMTSQGRLVIKNAKFADDLRPLDENCDCYTCQNYSRAYIRHLIKAEETFGIRLT
                     TIHNLHFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF"
     gene            59669..59929
                     /gene="yajC"
                     /locus_tag="RPH49_000175"
     CDS             59669..59929
                     /gene="yajC"
                     /locus_tag="RPH49_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDY5123375.1"
                     /translation="MQFSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRI
                     TTIGGIKGTVKAVDETTVVITVNGHGTELTFEKPAIKQVDPS"
     gene            60204..62483
                     /gene="secDF"
                     /locus_tag="RPH49_000176"
     CDS             60204..62483
                     /gene="secDF"
                     /locus_tag="RPH49_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500252.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecDF"
                     /protein_id="HDY5123376.1"
                     /translation="MKKSSRIIAFLLLVVLLFAGMAATYKSVIKNVNLGLDLQGGFEV
                     LYQVDPLNKGDKIDKKALQSTAQTLENRVNVLGVSEPKIQVEEPNRIRVQLAGVTDQN
                     EARKILSSQANLTIRDAEDKVKLSGSDIKQGSAKQEFKQETNQPTVTFKVKDKNKFKK
                     VTEEISKKRDNVMVVWLDFKKGDSYKKEAQKKNPKFISAASVDQPINSDSVEISGGFK
                     GQEGVKKAKQIAELLNAGSLPVDLKEIYSNSVGAQFGQDALDKTVFASFIGVALIYLF
                     MLGFYRLPGLVAIIALTTYIYLTLVAFNFISGVLTLPGLAALVLGVGMAVDANIIMYE
                     RIKDELRIGRTIKQAFSKANKSSFLTIFDSNLTTVIAAAVLFFFGESSVKGFATMLLL
                     GILMIFVTAVFLSRFLLSLLVSSNIFKNQFWLFGVKKNKRHDINEGVDVHDLKTSFEK
                     WNFVKLAKPLIGVSILIVVVGLVILYIFKLNLGIDFSSGTRVDFQSKQAITQQKVEQV
                     VKDSGLKADQIQINGKDNKVATVQFKDDLTRAQDNKLSDNIKSKFGDTPQINTVSPII
                     GQELAKNAMLALIYASIGIIIYVSLRFEWRMGLSSVLALLHDVFIIVAIFSLFRIEVD
                     LTFIAAVLTIVGYSINDTIVTFDRVRENLQKVKVITTTEQIDDIVNRSIRQTMTRSIN
                     TVLTVIVVVVAILFFGAPTIFNFTLALFIGLISGVFSSIFIAVPLWGIMKKRQLKKSP
                     KHKLVVYKEKKSNDEKILV"
     gene            62686..64959
                     /gene="recJ"
                     /locus_tag="RPH49_000177"
     CDS             62686..64959
                     /gene="recJ"
                     /locus_tag="RPH49_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDY5123377.1"
                     /translation="MIKPKYKWKLTKPAEYISDELTSKLKLTPIVKKILESKSIIDEQ
                     TIEAIISDTDINHDALQLSDMTKTIERIKRAIANDEKILVYGDYDADGVTSTTILVTT
                     LQLLGAQVGWHIPNRFTEGYGPNELAFRNAHDEGITLIITVDNGIQGHNEIKMVQDLG
                     VDVIVTDHHEIGSTLPEAYAIVHPMHPSFNYPFQQLCGAGVAYKLAQALIENVPDYFK
                     ALVAIGTIADLVSLTDENRSLVKQGLKVLNDQCPTSVKALLKEAGYNDNIDEETIGFI
                     IGPRLNAVGRLDDASLACELLMTDDEEEAAFLAEQVEHFNRERKDIVATITEEAMAMA
                     ETKVKKGDLFLLLAKENWHEGVLGIVASKIVETFALPTLILNIDREQNHAKGSARSID
                     QVSMFEILSAHQELIAKFGGHHMAAGMTMDIENIESLAEGLNKWMKELSKTTSLDPVK
                     PVDVLLTENDITIKNIRDMNRLRPFGTDFSRPIFEMDDLSVSSVKAIGQQKNHLKLTL
                     GESNIAALFWQNGHLEPELQDEQPINILGSVQINEWNGNQSPQLIIQDIAMNEQQILD
                     YRSKRKSLPFTENDENIVVLIHPKSDKVNANEYYYGEEIKHQTDKVVLRDLPTSMEDL
                     SNSLQQLQFSQLYIVLQHNHSIYFDGIPNMDIFKKCYKALITKQETNIQKEGMLLCQH
                     LSVKPDTLKFMLKVFLDLKFVTQEDGLIRINQQPDKRSIDSSKVYQLRQQRMDVEKQL
                     LYQDFSEIKNWIKSQLS"
     gene            64981..65499
                     /locus_tag="RPH49_000178"
     CDS             64981..65499
                     /locus_tag="RPH49_000178"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009559512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDY5123378.1"
                     /translation="MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYA
                     KDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLT
                     MHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIK
                     DYDVMSLISYDE"
     gene            65927..68116
                     /locus_tag="RPH49_000179"
     CDS             65927..68116
                     /locus_tag="RPH49_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDY5123379.1"
                     /translation="MNNEYPYSADEVLHKAKSYLSADEYEYVLKSYHIAYEAHKGQFR
                     KNGLPYIMHPIQVAGILTEMRLDGPTIVAGFLHDVIEDTPYTFEDVKEMFNEEVARIV
                     DGVTKLKKVKYRSKEEQQAENHRKLFIAIAKDVRVILVKLADRLHNMRTLKAMPREKQ
                     IRISRETLEIYAPLAHRLGINTIKWELEDTALRYIDNVQYFRIVNLMKKKRSEREAYI
                     ETAIDRIRTEMDRMNIEGDINGRPKHIYSIYRKMMKQKKQFDQIFDLLAIRVIVNSIN
                     DCYAILGLVHTLWKPMPGRFKDYIAMPKQNLYQSLHTTVVGPNGDPLEIQIRTFDMHE
                     IAEHGVAAHWAYKEGKKVSEKDQTYQNKLNWLKELAEADHTSSDAQEFMETLKYDLQS
                     DKVYAFTPASDVIELPYGAVPIDFAYAIHSEVGNKMIGAKVNGKIVPIDYILQTGDIV
                     EIRTSKHSYGPSRDWLKIVKSSSAKGKIKSFFKKQDRSSNIEKGRMMVEAEIKEQGFR
                     VEDILTEKNIQVVNEKYNFANEDDLFAAVGFGGVTSLQIVNKLTERQRILDKQRALNE
                     AQEVTKSLPIKDNIITDSGVYVEGLENVLIKLSKCCNPIPGDDIVGYITKGHGIKVHR
                     TDCPNIKNETERLINVEWVKSKDATQKYQVDLEVTAYDRNGLLNEVLQAVSSTAGNLI
                     KVSGRSDIDKNAIINISVMVKNVNDVYRVVEKIKQLGDVYTVTRVWN"
     gene            68128..68580
                     /locus_tag="RPH49_000180"
     CDS             68128..68580
                     /locus_tag="RPH49_000180"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDY5123380.1"
                     /translation="MKVVVQRVKEASVTNDTLNNQIKKGYCLLVGIGQNSTEQDADVI
                     AKKIANARLFEDDNNKLNFNIQQMNGEILSVSQFTLYADVKKGNRPGFSNSKNPDQAV
                     KIYEYFNDALRAYGLTVKTGEFGTHMNVSINNDGPVTIIYESQDGKIQ"
     gene            68577..69452
                     /locus_tag="RPH49_000181"
     CDS             68577..69452
                     /locus_tag="RPH49_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDY5123381.1"
                     /translation="MKKIEAWLSKKGLKNKRTLIVVIAFVLFIIFLFLLLNSNSEDSG
                     NITITENAELRTGPNAAYPVIYKVEKGDHFKKIGKVGKWIEVEDTSSNEKGWIAGWHT
                     NLDIVADNTKEKNPLQGKTIVLDPGHGGSDQGASSNTKYKSLEKDYTLKTAKELQRTL
                     EKEGATVKMTRTDDTYVSLENRDIKGDAYLSIHNDALESSNANGMTVYWYHDNQRALA
                     DTLDATIQKKGLLSNRGSRQENYQVLRQTKVPAVLLELGYISNPTDETMIKDQLHRQI
                     LEQAIVDGLKIYFSA"
     gene            69913..71175
                     /locus_tag="RPH49_000182"
     CDS             69913..71175
                     /locus_tag="RPH49_000182"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDY5123382.1"
                     /translation="MIKIPRGTQDILPEDSKKWRYIENQLDELMTFYNYKEIRTPIFE
                     STDLFARGVGDSTDVVQKEMYTFKDKGDRSITLRPEGTAAVVRSYIEHKMQGNPNQPI
                     KLYYNGPMFRYERKQKGRYRQFNQFGVEAIGAENPSVDAEVLAMVMHIYQSFGLKHLK
                     LVINSVGDMASRKEYNEALVKHFEPVIHEFCSDCQSRLHTNPMRILDCKVDRDKEAIK
                     TAPRITDFLNEESKAYYEQVKAYLDDLGIPYIEDPNLVRGLDYYTHTAFELMMDNPNY
                     DGAITTLCGGGRYNGLLELLDGPSETGIGFALSIERLLLALEEEGIELDIEENLDLFI
                     VTMGDQADRYAVKLLNHLRHNGIKADKDYLQRKIKGQMKQADRLGAKFTIVIGDQELE
                     NNKIDVKNMTTGESETIELDALVEYFKK"
     gene            71191..72957
                     /gene="aspS"
                     /locus_tag="RPH49_000183"
     CDS             71191..72957
                     /gene="aspS"
                     /locus_tag="RPH49_000183"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDY5123383.1"
                     /translation="MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDRE
                     GIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNI
                     KVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDD
                     EGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQI
                     VKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPR
                     MTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAE
                     QYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGD
                     LVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAA
                     HHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGF
                     TKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCL
                     LTNAPGEVSDKQLEELSLRIRH"
     gene            73035..73225
                     /gene="ssrS"
                     /locus_tag="RPH49_000184"
     ncRNA           73035..73225
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RPH49_000184"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            73290..73418
                     /locus_tag="RPH49_000185"
     CDS             73290..73418
                     /locus_tag="RPH49_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123384.1"
                     /translation="MGLIAFNKCFFVEFLKNNQSNNAKYKILSYYVLMYKSVKEVK"
     gene            73418..74191
                     /locus_tag="RPH49_000186"
     CDS             73418..74191
                     /locus_tag="RPH49_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA threonylcarbamoyladenosine dehydratase"
                     /protein_id="HDY5123385.1"
                     /translation="MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALART
                     NIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYT
                     EETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTIS
                     DISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQ
                     MPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ"
     gene            complement(74352..75626)
                     /locus_tag="RPH49_000187"
     CDS             complement(74352..75626)
                     /locus_tag="RPH49_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500242.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDY5123386.1"
                     /translation="MSTEPLASRMRPKNIDEIISQQHLVGPRGIIRRMVDTKKLTSMI
                     FYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIH
                     RLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQAL
                     TRAIEDDENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHV
                     TLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTI
                     VRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSA
                     MSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPD
                     KLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP"
     gene            75711..76133
                     /locus_tag="RPH49_000188"
     CDS             75711..76133
                     /locus_tag="RPH49_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDY5123387.1"
                     /translation="MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQ
                     LVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQ
                     LWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI"
     gene            76233..76415
                     /locus_tag="RPH49_000189"
     CDS             76233..76415
                     /locus_tag="RPH49_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDY5123388.1"
                     /translation="MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVV
                     ENAKNKITDAIDKLKK"
     gene            76455..76601
                     /locus_tag="RPH49_000190"
     CDS             76455..76601
                     /locus_tag="RPH49_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123389.1"
                     /translation="MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENE
                     DKEK"
     gene            complement(76838..77851)
                     /locus_tag="RPH49_000191"
     CDS             complement(76838..77851)
                     /locus_tag="RPH49_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDY5123390.1"
                     /translation="MAIKYSALNLVPIREGEDERTAINDMVKLAQHLDELSYERYWIA
                     EHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNR
                     VDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGK
                     NVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVI
                     VCLNTIVAENDEEAQYLASSMAQVMVSITRGRMQPVQPPTHDLQNILTPREYAMAMER
                     QKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEK
                     NTL"
     gene            78163..79305
                     /locus_tag="RPH49_000192"
     CDS             78163..79305
                     /locus_tag="RPH49_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDY5123391.1"
                     /translation="MEIYADYAATTPVKPEVVDAMMTIYNSHYGNPSSIHAKGRDARK
                     YLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSV
                     LHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYD
                     IQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVT
                     LDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQE
                     RAIPFELNGSMTDATGHIVNLYFPFVEVETMLTLLDMAQIYVSSGSACTAGSTQPSHV
                     LDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES"
     gene            79306..80424
                     /gene="mnmA"
                     /locus_tag="RPH49_000193"
     CDS             79306..80424
                     /gene="mnmA"
                     /locus_tag="RPH49_000193"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDY5123392.1"
                     /translation="MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTD
                     ENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMC
                     NKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQ
                     QQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQP
                     GDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHD
                     ALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEP
                     VRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV"
     gene            80941..81609
                     /locus_tag="RPH49_000194"
     CDS             80941..81609
                     /locus_tag="RPH49_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDY5123393.1"
                     /translation="MIDQQTIYQYIQNGKIEEALQALFGNIEEDPTIIENYINAGIVL
                     ADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQV
                     DCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQL
                     KHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKM
                     KEEE"
     gene            81611..84088
                     /locus_tag="RPH49_000195"
     CDS             81611..84088
                     /locus_tag="RPH49_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDY5123394.1"
                     /translation="MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDT
                     MPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLF
                     KGVGKKTAQNIVNALGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIM
                     IRLHDLGFGPKLSMAIYQFYLGDTLTILDQNPYQLIYDIKGIGFNKADQLARNIGIAY
                     NDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQY
                     LNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDA
                     NQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVN
                     DDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDE
                     MSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVY
                     RQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTM
                     ADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPN
                     DNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQ
                     GSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQ
                     LCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMPSNDSEEVTSDSTKTDTN
                     VLTEATMFKIDPMINMGEITPYDFIER"
     gene            84431..87061
                     /gene="alaS"
                     /locus_tag="RPH49_000196"
     CDS             84431..87061
                     /gene="alaS"
                     /locus_tag="RPH49_000196"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDY5123395.1"
                     /translation="MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSG
                     VATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQ
                     EAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWD
                     IGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYT
                     PLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNSEQDVAFK
                     VIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVAD
                     IMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAF
                     KLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLK
                     NITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVAD
                     TGIVYNGNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHS
                     ATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTKDEIDQVERLVNEEIWKG
                     IDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFK
                     IVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDE
                     EKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSK
                     LQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGG
                     TQPENISKSLSFIKDYIKNL"
     gene            87124..87384
                     /locus_tag="RPH49_000197"
     CDS             87124..87384
                     /locus_tag="RPH49_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDY5123396.1"
                     /translation="MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVG
                     YLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK"
     gene            87388..87816
                     /gene="ruvX"
                     /locus_tag="RPH49_000198"
     CDS             87388..87816
                     /gene="ruvX"
                     /locus_tag="RPH49_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDY5123397.1"
                     /translation="MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELG
                     IDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERL
                     STMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH"
     gene            87831..88139
                     /locus_tag="RPH49_000199"
     CDS             87831..88139
                     /locus_tag="RPH49_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDY5123398.1"
                     /translation="MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKK
                     EYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
                     "
     gene            88424..89062
                     /locus_tag="RPH49_000200"
     CDS             88424..89062
                     /locus_tag="RPH49_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDY5123399.1"
                     /translation="MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIK
                     QLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFEN
                     QVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYH
                     GFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE"
     gene            89065..89988
                     /locus_tag="RPH49_000201"
     CDS             89065..89988
                     /locus_tag="RPH49_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDY5123400.1"
                     /translation="MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQ
                     MTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVK
                     AQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQ
                     VQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTH
                     IMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYE
                     DEKFMLMDPIEEIQPDHRPFDEGFLYKQTVY"
     gene            90000..91268
                     /locus_tag="RPH49_000202"
     CDS             90000..91268
                     /locus_tag="RPH49_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDY5123401.1"
                     /translation="MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLG
                     GQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKT
                     GATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGA
                     MEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLE
                     VDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATV
                     VSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSK
                     KSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNS
                     LDAARHPLQIVQIKVDRPIYPNNMMRKEIG"
     gene            91268..91891
                     /gene="udk"
                     /locus_tag="RPH49_000203"
     CDS             91268..91891
                     /gene="udk"
                     /locus_tag="RPH49_000203"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDY5123402.1"
                     /translation="MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKD
                     QKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFK
                     PKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQY
                     LSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ"
     gene            91919..92395
                     /gene="greA"
                     /locus_tag="RPH49_000204"
     CDS             91919..92395
                     /gene="greA"
                     /locus_tag="RPH49_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDY5123403.1"
                     /translation="MENQKQYPMTQEGFEKLERELEELKTVKRPEVVEKIKVARSFGD
                     LSENSEYDAAKDEQGFIEQDIQRIEHMLRNALIIEDTGDNNVVKIGKTVTFVELPGDE
                     EESYQIVGSAESDAFNGKISNESPMAKALIGKGLDDEVRVPLPNGGEMNVKIVNIQ"
     gene            92722..93456
                     /gene="pxpB"
                     /locus_tag="RPH49_000205"
     CDS             92722..93456
                     /gene="pxpB"
                     /locus_tag="RPH49_000205"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDY5123404.1"
                     /translation="MDVRFINEQTIMIYFENNISEETYRNVTAMVRWIREKEILEIQD
                     IVPSYRAVLIYFDEQAITSSKLIENLELNKFNEKNVHAVNQTNRIIKIPVQYGGTYGP
                     DIEEVAKHNRITVEQVIEKHTSKPYLIYMLGFMPGFPYLGGLDQQLHTPRRNQPRLKI
                     HAGSVGIANNQTGLYPSDSPGGWQIIGRTPLKVFSSEREPMSMYEAGEWIQFYAIDEQ
                     EFIQIERDISDGNFNVDDWVVIENVN"
     gene            93446..94456
                     /locus_tag="RPH49_000206"
     CDS             93446..94456
                     /locus_tag="RPH49_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HDY5123405.1"
                     /translation="MSIKILQPGLFSTVQDLGRKGYEHIGFSGSGAMDQFSFKVAQSL
                     INNDGPAIEYTLIGPTIQFNTQNTFVITGGSVNASLNNKTISMNSVILAEKGDILKIG
                     AITKGARGYLTFGHSINVPSIAESYATHTRSSIGGFKGRKLLANDVITVKINNDFKEN
                     IGKTIHLQDDLLPENNIIHILQGPQFEAFSEEARAKIVNYPYLITEQSDRMGYRLEGD
                     SVAPINQADIISEPVALGSVQVPNDGQPIILLNDKQTIGGYTKIATVCKFDLPKLAQM
                     KPQDTIQFKWISFQEAVDKNREQMSLFNEILKSHQKTPIFDTSSLRHTSKKLATILKG
                     DL"
     gene            94458..94907
                     /locus_tag="RPH49_000207"
     CDS             94458..94907
                     /locus_tag="RPH49_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="HDY5123406.1"
                     /translation="MNIEKIEQIIKLVKENDVKKFKYKNFEDEIEINFTDSNHLAAHS
                     NQSNQSMNNNDLTASKANDNSDVSTNDYHDIKSPMVGTFFLQDSKELTEPIVKVGDKV
                     NKGDIIGYVEAMKVLNEVTTDVAGEITEIVADHGTNVEYDQVLVRIK"
     gene            94921..96282
                     /locus_tag="RPH49_000208"
     CDS             94921..96282
                     /locus_tag="RPH49_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDY5123407.1"
                     /translation="MLRCLIANRGEIAVRIIRACREYGIETVAVYAKRDEQSLHVHLA
                     DQAICIGEANALDSYLNIDRIISAAQITGANAIHPGYGFLSESTKFAQTVEEQGIAFI
                     GPTKKTMEMMGDKITARQTVHHAGVPVIPGSNGAVNHVSEIEKLAKDIGYPVVIKAAS
                     GGGGKGIRIVKKAEDLEKAFKEAKSEGKKYFDDDRVYVEAFIPVAKHVEVQVMGDGQD
                     NYVHLGERDCSVQRKNQKLIEESPCAALTEERRQQICNDAVKVARAANYRSAGTIEFL
                     VTDTAHYFIEMNARIQVEHTVTEMRAERDLVAAQLYLLEHNHLPFSQSDIQFNGHVIE
                     ARINAENPEKKFQPTPGKVTALHLPQGFNVRVDSLLYHGYQVSPYYDSLVAKVIVKSH
                     DRASAIDKLKATLDEMVIDGFSTTADFLYAVLNYPLYRDGDAKDVDIKFLEKHQIVKG
                     VEL"
     gene            96282..97034
                     /gene="pxpA"
                     /locus_tag="RPH49_000209"
     CDS             96282..97034
                     /gene="pxpA"
                     /locus_tag="RPH49_000209"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDY5123408.1"
                     /translation="MRVDLNCDLGEAFGNYSFGGDHQIIPLITSANVACGFHAGDENV
                     MNETVKLAKAHNVAVGAHPGLPDLKGFGRRNIDISNDEIYNLMIYQLGALQGFCRIHQ
                     VKINHVKPHGALYQMGAKDREIASVIAQAVYDFDPSLVLVGLANSYLISEAKNVGLIT
                     ASEVFADRRYEDDGQLVSRKESDAVITDTDEALKQVLKMVKENKVISKNNKEVTLQAD
                     TICVHGDGEHALLFVSKIREILMKEGIDIQSL"
     gene            97046..98278
                     /locus_tag="RPH49_000210"
     CDS             97046..98278
                     /locus_tag="RPH49_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HDY5123409.1"
                     /translation="MGRNLKLKHRESDFEFTKNHKRLLLGSVFLMATSAIGPAFLTQT
                     AVFTSQFLASFAFAILLSIIIDIGAQINIWRILVVTGLRGQEISNKVVPGLGTVISIL
                     IAFGGLAFNIGNIAGAGLGLNAIFGLDVKWGAAITAIFAILIFVSKSGQKIMDVVSMI
                     LGIVMILVVAYVMFVSNPPYGDAFVHTFAPEHPMKLVLPIITLVGGTVGGYITFAGAH
                     RILDSGIKGKQYLPFVNQSAIAGILTTGIMRTLLFLAVLGVVVTGVTLSSENPPASVF
                     EHAIGPIGKNIFGIVLFAAAMSSVIGSAYTSATFLKTLHKSLDERSNLIVIVFIVIST
                     MIFLFIGKPISLLIIAGAINGWILPITLGAILIASKKKSIVGDYKHPNWMFIFGIVAV
                     LVTILTGIFSFKEVLQLF"
     gene            98570..99790
                     /locus_tag="RPH49_000211"
     CDS             98570..99790
                     /locus_tag="RPH49_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDY5123410.1"
                     /translation="MGYRTLKSIFHEHNESKMKDEYTKRFNSLASFNTNINIIPMENG
                     KKVNDLEYPLFFMVTKNLSKKQELISINSRKIDRALNSLPYAAREQYFNDLLIDELQS
                     TNEIENVFSTKQEIAHALNNQASEFLKFRGLVDQYKEIELNKKIKVDNVRDIRAIYDK
                     LVSNEINEQDKLDGELFRKNFVGVHDGSTNKYIHVGLQPETKIVEYIGEMLTFLKYFD
                     APQPFKIMASHYLFEYIHPFYDGNGRVGRFIIAKLLSDYYDNYTALTFSYVINRNKSK
                     YYKAFMTASNHLNCGDLTEFIDTMLELLIAGQERILDELIPKMDATEKLTLYLTSHYK
                     QIDYEFLYLLSMDKLFGNKRNRLTLIDLENILGVGRVKINNTIKKFGNYLVKIKSRPT
                     IYEISDEFLNSIIK"
     gene            100393..101144
                     /locus_tag="RPH49_000212"
                     /pseudo
     CDS             100393..101144
                     /locus_tag="RPH49_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503564.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="exotoxin"
     gene            complement(101346..101615)
                     /locus_tag="RPH49_000213"
     CDS             complement(101346..101615)
                     /locus_tag="RPH49_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123411.1"
                     /translation="MAENNQNSLVTKIATYGSFIAIASFVILFISIFLKFSFNIEFTA
                     TIMNICRYTLILGFILMSLPDVVDKNIKKIIFDAFIIIVFIFFLL"
     gene            101929..102615
                     /gene="mtnN"
                     /locus_tag="RPH49_000214"
     CDS             101929..102615
                     /gene="mtnN"
                     /locus_tag="RPH49_000214"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDY5123412.1"
                     /translation="MIGIIGAMEEEVTILKNKLTQLSEISVAHVKFYTGILKDREVVI
                     TQSGIGKVNAAISTTLLINKFKPDIIINTGSAGALDESLNVGDVLISDDVKYHDADAT
                     AFGYEYGQVPQMPVAFQSSKPLIDKVSQVVQQQQLTAKVGLIVSGDSFIGSVEQRQKI
                     KKAFPNAMAVEMEATAIAQTCYQFNVPFVVVRAVSDLANGEAEMSFEAFLEKAAVSSS
                     QTVEALVSQL"
     gene            102635..103162
                     /locus_tag="RPH49_000215"
     CDS             102635..103162
                     /locus_tag="RPH49_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDY5123413.1"
                     /translation="MGLVRKFFMPNSYVQSIFQIDLDKLVDKGVKGIITDLDNTLVGW
                     DVKEPTERVKAWFKEANEKGITITIVSNNNESRVASFSQHLDIDFIFKARKPMGKAFD
                     KAITKMNIRPDQTVVIGDQMLTDVFGGNRRGLYTIMVVPVKRTDGFITKFNRLIERRL
                     LRHFSKKGYITWEEN"
     gene            103163..104263
                     /gene="yqeH"
                     /locus_tag="RPH49_000216"
     CDS             103163..104263
                     /gene="yqeH"
                     /locus_tag="RPH49_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDY5123414.1"
                     /translation="MSDILKCIGCGAPLQSEDKNKPGFVPEHNMFRDDVICRRCFRLK
                     NYNEVQDVGLESEDFLKLLSGLADKKGIVVNVVDVFDFEGSFINAVKRIVGNKKIILA
                     ANKLDLLPKQINKRRVKEWLKRTARKYGLEADDVVLISAEKGWGIDDLLSSIANIREN
                     EDVYIVGTTNVGKSTLINKLIEASVGEKDVVTTSRFPGTTLDMIDIPLDETSFMYDTP
                     GIIQDHQMTHLVSEKELKIIMPKKEIKQRVYQLNEAQTLFFGGLARIDYVSGGKRPLV
                     CFFSNDLNIHRTKTEKANDLWRNQLGDLLTPPGNPQNFDLNEVKAVRLETGKEKRDVM
                     ISGLGFITIGPGAKVIVRVPKNVDVVLRNSIL"
     gene            104277..105083
                     /gene="aroE"
                     /locus_tag="RPH49_000217"
     CDS             104277..105083
                     /gene="aroE"
                     /locus_tag="RPH49_000217"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDY5123415.1"
                     /translation="MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHL
                     IKEIISKKELDGFNITIPHKERIIPYLDHVDEQAINAGAVNTVLIKDGKWIGYNTDGI
                     GYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
                     INQISIADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPI
                     LEEAERKGNHIYNGLDMFVYQGAESFKIWTNKDADINSMKTAVLQQLKGE"
     gene            105087..105377
                     /gene="yhbY"
                     /locus_tag="RPH49_000218"
     CDS             105087..105377
                     /gene="yhbY"
                     /locus_tag="RPH49_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDY5123416.1"
                     /translation="MLTGKQKRYLRSLAHNIDPIFQIGKGGINENMIKQIDDTLENRE
                     LIKVHVLQNNFDDKKELAETLSEATRSELVQVIGSMIVIYRESKENKEIELP"
     gene            105380..105949
                     /gene="nadD"
                     /locus_tag="RPH49_000219"
     CDS             105380..105949
                     /gene="nadD"
                     /locus_tag="RPH49_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate (nicotinamide) nucleotide
                     adenylyltransferase"
                     /protein_id="HDY5123417.1"
                     /translation="MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPL
                     KKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELY
                     FVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIR
                     QRVSEGKSIQVLVPKSVENYIKGEGLYEH"
     gene            105939..106523
                     /gene="yqeK"
                     /locus_tag="RPH49_000220"
     CDS             105939..106523
                     /gene="yqeK"
                     /locus_tag="RPH49_000220"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDY5123418.1"
                     /translation="MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVE
                     LAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEV
                     LMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISK
                     RTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD"
     gene            106524..106877
                     /gene="rsfS"
                     /locus_tag="RPH49_000221"
     CDS             106524..106877
                     /gene="rsfS"
                     /locus_tag="RPH49_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDY5123419.1"
                     /translation="MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNN
                     ERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEK
                     LYQDAPLESYSQVAY"
     gene            106880..107596
                     /locus_tag="RPH49_000222"
     CDS             106880..107596
                     /locus_tag="RPH49_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5123420.1"
                     /translation="MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGT
                     GSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDS
                     LNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWD
                     AVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKQVETFT
                     DFNIDEHNEDAERLFFIAKK"
     gene            107636..>107713
                     /locus_tag="RPH49_000223"
     CDS             107636..>107713
                     /locus_tag="RPH49_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HDY5123421.1"
                     /translation="MVLLYQFLLRYKDFLTQWKLYIISAV"
BASE COUNT        38806 a        14626 c        20681 g        33600 t
ORIGIN      
        1 ctcattcaga tttacccaat atttttactt ttataatgta atgcgtttta tccaagttat
       61 ttttttaaaa ataaatattg aattaggggc tgatttcatg tcattaagag atgaagcatt
      121 ggaaatgcac aaacgtaatc aaggtaaatt agaagttaaa ccaaatgtaa aagttactaa
      181 taaagaggaa ttaagtttag catattcacc tggcgttgct gaaccgtgta aagatatata
      241 tgaagataaa agaaaagtgt atgattacac aatcaaaggg aatacagttg cagttattac
      301 tgatggaaca gcggtattag gtttaggtaa cattggacct gaagcaagta ttcctgtaat
      361 ggaaggtaaa gcagtattat tcaaaagctt cgctggtatc aatgggatgc ctattgcgtt
      421 aaatacaact gataccgaag aaatcattaa aacagttaag ttgttagaac ctaattatgg
      481 tggtattaat ttagaggata tttcggcacc acgttgtttt gaaattgaag aacgattgaa
      541 aaaagaaact aatattccgg tattccatga cgatcaacat ggtacagcaa ttgtaacaat
      601 ggcaggtttg gtaaatgcat tgagagttgt taacaaagat attgctaaaa taaaagttgt
      661 actaaatggt gctggtgcag caggaatagc cattgttaaa ttactatacg cgtatggtgt
      721 aagaaatatg gttatgtgtg actcaagagg cgcaattttt gaaggacgtt catatggtat
      781 gaatcctacg aaagatgttg tagctaaatg gacaaataaa gataagattg aagggtcttt
      841 agaagaagtc gtaaaagacg cagatgtatt tatcggagtt tctgtagcta atgcgctgtc
      901 acaagatatg gttaagagta tggcagataa tccaattata tttgcaatgg ctaatccaaa
      961 tcctgaaata atacctgatg atgccaaagc ggcaggtgca cgcgttgttg gtactggacg
     1021 ttcagattat cctaaccaaa ttaataatgt attagctttc cctggtattt ttagaggtgc
     1081 attagaggtt gaagctacac atataaatga agaaatgaaa aaagcagctg tagaagcgat
     1141 tgctgattta atcgatagtt ctgaattaaa tgaagactac tgtatcccag gaccgtttga
     1201 taaacgtgta gcgccatcag ttgctcgtaa tgttgctaaa gcggcaatgg aatctggagt
     1261 agctaggatt gaagttgatc cgcaagatgt gtatgataaa acaatgaaac ttacagattt
     1321 acaataaaaa taattaacgt ttaattaaat tgcttaaaag ttagcaataa agattcatta
     1381 aaatgatgaa aatgaaagtt tatgataaac attcaacagt caaacgaata taaatcaaat
     1441 aaatttaaac ccgtttttaa ctggtcaagt tcagtttaag gctctaaatg gttagaacag
     1501 aggttatttg gaggttttcc tatgtttaaa gattttttta atcgaacaaa gaaaaagaaa
     1561 tatcttacag tacaagactc taaaaataat gatgtgcctg caggtattat gactaagtgt
     1621 ccaaagtgta agaaaattat gtacacaaaa gaattagctg aaaatttaaa tgtgtgcttt
     1681 aattgtgatc atcatattgc tttaactgcg tataaacgta tagaagcaat ttctgatgaa
     1741 ggatcattta cagaattcga taagggaatg acctctgcga atccattaga ttttccaagt
     1801 tatttagaaa aaattgaaaa ggaccaacaa aagacaggtc ttaaagaagc agttgtgact
     1861 ggtacagcgc aactagatgg tatgaaattt ggcgttgctg tcatggattc acgttttaga
     1921 atgggaagta tgggatcggt tatcggtgaa aagatatgtc gcatcattga ttactgcact
     1981 gagaaccgtt taccatttat tcttttctct gcaagtggtg gtgcacgtat gcaagaaggt
     2041 attatttcct tgatgcaaat gggtaaaacc agtgtatctt taaaacgtca ttctgacgct
     2101 ggactattat atatatcata tttaacacat ccaactactg gtggtgtatc tgcaagcttt
     2161 gcatcagttg gtgatataaa tttaagtgag ccaaaagcgt tgataggttt tgcaggtcgt
     2221 cgagttattg aacagacaat aaacgaaaaa ttgccagatg atttccaaac tgcagaattt
     2281 ttattagagc atggacaatt ggacaaagtt gtacatcgta atgatatgcg tcaaacattg
     2341 tctgaaattc taaaaatcca tcaagaggtg actaaataat gttagatttt gaaaaaccac
     2401 tttttgaaat tcgaaataaa attgaatctt tgaaagaatc tcaagataaa aatgatgtgg
     2461 atttacaaga agaaattgac atgcttgaag cgtcattgga acgagaaact aaaaaaatat
     2521 atacaaatct aaaaccatgg gatcgtgtgc aaattgcgcg tttgcaagaa agacctacga
     2581 ccctagatta tattccatat atctttgatt cgtttatgga acttcatggt gatcgtaatt
     2641 ttagagatga tccagcaatg attggtggca ttggcttttt aaatggtcgc gctgttacgg
     2701 ttattggaca acaacgcgga aaagatacaa aagataatat ttatcgaaat tttggtatgt
     2761 cgcatccaga aggttatcga aaagcattac gtttaatgaa acaagctgaa aagttcaatc
     2821 gtcctatctt tacatttata gatacaaaag gtgcatatcc tggtaaagct gcggaagaac
     2881 gtggacaaag tgaatctatc gcaacaaatt tgattgagat ggcttcacta aaagtaccag
     2941 ttattgcgat tgtcattggt gaaggtggca gtggaggtgc tctaggtatt ggtattgcca
     3001 ataaagtatt gatgttagag aatagtactt actctgttat atctcctgaa ggtgcagcgg
     3061 cattattatg gaaagacagt aatttggcta aaattgcagc tgaaacaatg aaaattactg
     3121 cccatgatat taagcaatta ggtattatag atgatgtcat ttctgaacca cttggcggtg
     3181 cacataaaga tattgaacag caagctttag ctattaaatc agcgtttgtt gaacagttag
     3241 attcacttga gtcattatca cgtgatgaaa ttgctaatga tcggtttgaa aaattcagaa
     3301 atatcggttc ttatatagaa taatcaactt gagcattttt atgttaaatc gatactgggt
     3361 tttaccataa attgaagtac attagaacaa taatttaata tttagatact gaattttaac
     3421 taagattagt agtcaaaatt gtggctacta atcttttttt aattaagtta aaataaaatt
     3481 caatatttaa aacgtttaca tcaattcaat acattagttt tgatggaatg acatatcaat
     3541 ttgtggtaat ttagagttaa agataaatca gttatagaaa ggtatgtcgt catgaagaaa
     3601 attgcagttt taactagtgg tggagattca cctggaatga atgctgcggt aagagcagtt
     3661 gttcgtacag caatttacaa tgaaattgaa gtttatggtg tgtatcatgg ttaccaagga
     3721 ttgttaaatg atgatattca taaacttgaa ttaggatcag ttggggatac gattcagcgt
     3781 ggaggtacat tcttgtattc agcaagatgt ccagagttta aggagcaaga agtacgtaaa
     3841 gttgcaatcg aaaacttacg taaaagaggg attgagggcc ttgtagttat tggtggtgac
     3901 ggtagttatc gcggtgcaca acgcatcagt gaggaatgta aagaaattca aactatcggt
     3961 attcctggta cgattgacaa tgatatcaat ggtactgatt ttacaattgg atttgacaca
     4021 gcattaaata cgattattgg cttagtcgac aaaattagag atactgcgtc aagtcacgca
     4081 cgaacattta tcattgaagc aatgggccgt gattgtggag atctagcatt atgggctgga
     4141 ttatcagttg gtgctgagac aattgtagta ccagaagtga aaacagatat taaagaaata
     4201 gctgataaaa ttgaacaagg tattaaacgt ggtaagaaac actcaatcgt tcttgtagca
     4261 gaaggttgca tgactgcgca agattgtcaa aaagaattat cacaatacat caatgttgat
     4321 aatagagtgt ctgtgttagg tcacgttcaa cgtggtggta gcccaacagg tgcggataga
     4381 gttttagcat cacgtttagg tggatatgcg gtagacttat taatgcaagg tgaaacagct
     4441 aagggtgttg gaattaagaa caataaaatt gtagcaacat cttttgatga aatttttgat
     4501 ggtaaagatc ataaatttga ttatagtcta tatgaacttg ctaacaagtt atctatataa
     4561 gatttcagga ggaattataa aatgagaaaa actaaaattg tatgtacaat tggaccagct
     4621 tcagaatcag aagaaatgat tgagaaatta atcaatgctg gtatgaacgt tgcacgatta
     4681 aacttttcac atggtagtca tgaagagcat aaaggtagaa ttgatacaat tcgtaaagta
     4741 gctaaaagat tagacaaaat tgtagcaatt ttattagata cgaaaggtcc agaaattcgt
     4801 acgcataata tgaaagacgg tatcattgaa cttgaacgtg gtaacgaagt tattgttagc
     4861 atgaatgaag ttgaaggaac accggaaaag ttctcagtaa catatgaaaa cttaattaac
     4921 gatgttcaag taggttcata cattttactt gatgatggct taattgaatt acaagttaaa
     4981 gatattgacc atgctaaaaa agaagttaaa tgtgatattt taaactctgg tgagcttaaa
     5041 aacaaaaaag gtgttaactt acctggtgta agagtaagtt tacctggtat tacagaaaaa
     5101 gatgctgaag atatccgttt cggtattaaa gaaaatgttg acttcattgc agcaagtttc
     5161 gtacgtcgtc ctagtgatgt tttagaaatt cgtgaaattt tagaagaaca aaaagctaac
     5221 atttcagtat tccctaaaat tgaaaaccaa gaaggtattg ataatattgc ggaaattctt
     5281 gaagtgtctg atggtttaat ggttgcacgt ggtgacatgg gtgttgaaat tccacctgaa
     5341 aaagtaccaa tggttcaaaa agatttaatc agacaatgta acaaattagg taaaccagtt
     5401 attacagcta cacaaatgtt agattctatg caacgtaacc cacgtgctac acgtgcagaa
     5461 gctagtgacg ttgccaacgc aatctatgat ggtacagatg cagtaatgtt atctggtgaa
     5521 actgctgctg gtttatatcc tgaagaagct gttaaaacaa tgagaaatat tgctgtatca
     5581 gctgaagcag cccaagatta caaaaagtta ttgtcagatc gtactaaatt agttgaaact
     5641 tcattagtga atgcaatcgg tatttcggtt gcacatacag ctttaaactt aaatgttaaa
     5701 gcaattgtag ctgctactga aagtggttca acggcacgta ctatctctaa atatcgtccg
     5761 cattcagaca ttattgcagt gactccaagt gaagaaactg cacgtcaatg ttcaattgtt
     5821 tggggtgttc aacctgtagt taaaaaagga cgtaagagta cagatgcatt gttaaacaat
     5881 gcagttgcaa cagctgttga aactggtaga gtaactaatg gtgatttaat cattattact
     5941 gctggtgtac caactggtga aactggaact actaatatga tgaaaatcca cctagttggt
     6001 gacgaaattg ctaatggtca aggtattgga cgtggatcag ttgttggaac tacgttagtt
     6061 gctgaaactg ttaaagattt agaaggtaaa gatttatctg acaaagttat cgttactaac
     6121 tcaatcgatg aaacttttgt accttatgta gaaaaagctt taggcttaat tacagaagaa
     6181 aatggtatta catcaccaag tgcaattgtt ggtttagaaa aaggtattcc aacagttgta
     6241 ggtgtagaaa aagctgttaa aaacataagc aataacatgt tagttacgat tgatgctgct
     6301 caaggtaaaa tctttgaagg atatgcaaac gtactataat ttataaataa agacgtcttt
     6361 ccatttatca actatggaaa gacgtttttt tggtttatct ggtattttat gactcaatta
     6421 ataggttatt tgataaagat aatgtatgaa tagcaatcta tataaatatt tatatctttt
     6481 atacatgtac attatcagct ttaaactttc actcatttta ctttggaaag ttattataaa
     6541 atagaaatat ggatgtattt ctgaaatgat acattattaa atagatgaga aagtaaaagt
     6601 attgagccaa gttcgcaatt taatatataa gttgcatata aaaacccctg ttgaacttta
     6661 atatattcaa caggggtaaa acttgttatt agttatttga tttagcagcg atacgtttat
     6721 atcttaagta cataaatcct aatagtataa accaaatggg aataaagtat atcgcacgtc
     6781 ttgtttcaac attgataaac aataggccaa acacaaaaat aaagaataca aaaatgagat
     6841 agcccatata ttttccgcca aataatttat acgtagcctt tttatgaagg tctggatttt
     6901 tacgactata attgatataa gcgatgataa tcagtcccca aacaactaag aataatactg
     6961 tagagattgt tgtcacatac gtaaatacct tagtagcatc agggaaaata tagtttaata
     7021 atgctgccac gagtaacaat gccgatgaag caaagattgc tacatgtgga acgccatact
     7081 tattcgtctt agagaaattc ggtggtgctt gttgttgact tgataaaccg aacagcatac
     7141 gactattcga gaaaatacca ctgttacatg atgaagcagc agcagttagt actacaaaat
     7201 taatcaagcc tgcagcaaat ggaattccaa ttaatgcgaa caattttacg aatggactgt
     7261 tatcaggatc aacttgttgc caaggaataa tcgacatgat aaccgctaga gcaccgacat
     7321 aaaatattaa aattctaata ggaacactat taatagcttt tggtattgtt ttaacaggat
     7381 ttttcgtttc acctgccgta acaccaatca tttcgattcc cacgaatgag aataaggcca
     7441 tttggaatga cataaagaat ccagatgctc ctttagggaa tacaccgtgc tcgtataggt
     7501 ttgtgaaact cgcatgtcca aattgagttt tatatgcaaa tagaatcata acgaaaccta
     7561 cgacaattaa accaatgatt gttgctattt taatgataga gaaccaaaat tctaactctc
     7621 caaatagtct cgcactcaat aagttaaaag acattaataa caatacgcaa aaaagtgcac
     7681 taatccagtt tggaatttct gggaaccaga agcttacata ctttgctaca gctgttactt
     7741 cagccatacc tgtaataatc caacagaacc agtatgtcca accggttacg aatcctgcaa
     7801 aaggcccaat gtatgtattg gttacatctg cgaaagattt aaattcagta ttttgaatga
     7861 tgatttcacc taaacctcgc ataaacataa ataacataaa tccaataatg atatatgtta
     7921 gtaatataga agggccagtt aatgcaatcg tttgaccagc gcctaagaat aagcctgtac
     7981 caattgcgcc accaatagca attaattgaa tgtggcgatt gctcagttcc ctttgtaatt
     8041 tttcagccat aatacatctc ccttaaatat agatatgttt attatgcact tatattagga
     8101 tatatacaat tattttcggt aaaaatgtgt aaaattccat gttaatatac tttggatttt
     8161 ataatcatat ataataacca attgaaaatt ttattctatg ctaaaagttg gtgatgaata
     8221 taatcttgaa aaagctttaa tagagctatt tgtggctatt ctgtgacatt tacatagaat
     8281 tccaaaataa ttgttgcaca tataatgcca gtttttatat ttcacaaacg aataacgttt
     8341 agctataata ttagttgaaa gccatttcat aaagaaacag taaaggggaa atttatcatg
     8401 gcagaattac aaagaggttt agaaggggtt atcgcagcgg agactaagat aagttcaatt
     8461 attgaaagtc aattaacata tgccggctat gatattgatg atctagctga aaacgcgcaa
     8521 tttgaagaag tcattttcct attatggaat tacagattgc caaatgaaga agagctagct
     8581 catttaaagg ggaaattaaa tcaatacatg acattaaatc ctcgtgtgta tacacatttt
     8641 gaggagtatg ttacagatca cgtgcatcca atgacagcat tacgtacgtc attatcatat
     8701 attgcacatt tcgatcctga tgcagaaaat gaatcagatg aaaatcgtta tgaaagagca
     8761 atgcgtatac aggctaaagt agcatcatta gttacagcgt ttgctcgagt aagacaagat
     8821 aaagaaccac ttaagcctaa tcctgactta agttatgcgg caaacttcct atatatgtta
     8881 cgtggggaat taccaacaga tatagaagta gaagccttca ataaagcact tattttacac
     8941 gctgatcatg agttgaacgc atctgcattt acagcacgtt gtgcggtatc atcattgtca
     9001 gatatgtact caggtattgt agcagctgta ggttctctga aagggccatt acatggtggt
     9061 gcaaacgaac aagttatgac gatgttatct gagattgggt caattgaaaa tgttgatgct
     9121 tacttagatg aaaaatttgc gaataaagat aaagtaatgg gcttcggtca tcgtgtatat
     9181 aaagatggtg atcctagagc gaaatattta agagaaatga gccgtcaaat tacgaaagac
     9241 gctggtcgtg aagaattatt tgaaatgtca gtgaaaatgg aaaaacgtat ggcagaagaa
     9301 aaaggattaa ttcctaatgt tgatttttat agtgcgagtg tttatcactg tatggaaata
     9361 cctcatgatt tattcacgcc aatctttgct gtaagtcgtt ctgcaggatg gattgctcat
     9421 attttagaac aatataaaga taatagaatt atgcgtccta gagcaaaata tattggcgaa
     9481 acgaatcgta agtatattcc gcttgaagaa agaaaataat cgatacaaat taaaaatgaa
     9541 gatgtaaaat ttggaggtaa aataactatg actgcagaaa aaattactca aggaactgaa
     9601 ggattaaacg tacctaatga accaattatc ccatttatta tcggtgatgg aattggaccg
     9661 gatatttgga aggcagcaag ccgagtgata gatgctgctg ttgagaaagc ttataatggc
     9721 gaaaaacgca ttgaatggaa agaagtgcta gctggccaaa aagcatttga tacaactggc
     9781 gaatggttac ctcaagaaac acttgataca attaaagaat atttaattgc tgttaaagga
     9841 cctttaacaa caccaattgg tggtggtatt agatcattaa atgtggcttt acgccaagaa
     9901 ttagatttat ttacttgttt aagaccggta cgttggttta aaggagtacc atcacctgtt
     9961 aaacgtccac aagatgttga tatggttatt ttccgtgaaa atactgaaga catttatgct
    10021 ggtattgaat ttaaagaagg tacaacagaa gttaaaaagg taattgactt cttacaaaac
    10081 gaaatgggtg cgacaaacat tcgattccca gaaacttcag gtattggtat taaaccagtt
    10141 tctaaagaag gtactgagcg attagttaga gcagctattc aatatgctat cgataataac
    10201 cgtaaatcag ttactttagt tcataaaggt aatattatga aatttacaga aggctcattt
    10261 aagcagtggg gttacgattt agcattaact gaatttggtg atcaagtatt tacttggcaa
    10321 caatatgacg aaattgttga aaaagaaggc agagatgctg ctaattctgc acaagaaaaa
    10381 gctgaaaaag aaggcaagat tatcattaaa gattctattg ctgacatttt cttacaacaa
    10441 attttaactc gtccagctga gcatgatgtt gtagcaacta tgaacttgaa tggtgactat
    10501 atttcagatg ctttagctgc acaagttggt ggtattggta ttgcgccagg tgcaaacatt
    10561 aattatgaaa caggtcatgc tatttttgaa gcaacacatg gtacagctcc aaaatatgca
    10621 ggtttaaata aagtgaatcc atcttcagta attttaagtt ctgtattaat gttagaacat
    10681 ttaggatggc aagaagcggc agataagatt acagattcaa ttgaagatac aattgcttca
    10741 aaagttgtta cttatgactt tgcccgttta atggatggtg ctgaagaagt ttctacatca
    10801 gcatttgcag atgaattgat taaaaattta aaataaatac taattattta ggtgagtcta
    10861 gctactttaa ttgctaggtt cgccttttta aatgaattga agttggcagc aggacagaaa
    10921 taataaagag tcactaatga ttgattatat agtgtttctt acacattaga caaagcgatt
    10981 gtgtacataa gtttaggaat aaatgagtaa aactcatgca taggtagtgg catagaaatg
    11041 atattttcac aaagtttatt tcgttgtccc agagtaagtc atgtaaatta tagaaggaaa
    11101 tataagaagt attttattta tgtgtaaagt aatgtaaaaa atgtgtaaag ataatgtgta
    11161 ggatgttatt tttataaata gttcggttat aatgtaaata taattataag ttagggaggc
    11221 ataccatgtc gcaaaaagtg ttggtagtag atgacgaaca ttcaatcgta acattactta
    11281 aatataactt agaaacagct ggttatgaag ttgttgtcgc atttgatggt gatgaggctt
    11341 tagaaaaggt ggaaaatgaa cagccagatt taattatttt agatgttatg ctacctaaaa
    11401 aagatggcat tgacgtatgt aagactgtaa gaacaaataa aaatttagtc cctatattaa
    11461 tgttaacggc gaaaaatgat gaatttgatc gggtattagg tttagaatta ggtgccgatg
    11521 actatatgac taagcctttt tcacctagag aagttgttgc ccgtgtgaaa gccattttaa
    11581 gacgttctca atttgtaaaa gaagtagaag agattgacga tgatattacc atcggatcga
    11641 tacgtattag acccgattat tttgaagtat ataagcataa tgagctattg gagctaacac
    11701 cgaaagaatt tgaactgttg ctttatttga tagaaagaca aggcagagtc attacgagag
    11761 agcatatgtt aaatacggta tggaattatg aatttgcagg agactcaaga attgttgatg
    11821 tacatatcag tcatttaaga gataaattag aagataatcc taaggagcca caacttatta
    11881 aaactgtgcg tggcttaggc tataaattgg aaagacctaa agaacaatga tgaagtttca
    11941 ccaccgctta atgttattga taagcagtat attaattatc agttttgtta cattaggcat
    12001 tattattcac gcttccatca catatgtgtt atcagaaaaa cacgaacaag ctctagcaac
    12061 agatgcaaga tcatatattt atttagtcca agataatgag attgataaag ttaaagaaat
    12121 tgtaaaacag caaaatatag atttattgat aactaaaaat gataaaaagg tgtttagtag
    12181 tggcaaactg aaagccactc aaaatagtga tagctatatt caaaaaaagg acgtttttat
    12241 ttttaataag aaggttaacg gttatcatgt atggattaaa ggttacaata acgatattac
    12301 agaaatgcat tggacgttgt ggaaatatct tattttgaca tgtttagttg tactcatttg
    12361 tctgtatttt gcaagccgta gttttaagcg tacattaatc cgtcccattc aagaagttac
    12421 ttatgcaaca caattgttgg caaatggtta ttatcacata cgtgtacctg aaagtaatgt
    12481 tatagaaact aaagcgcttt ttgtgtctac caatgatcta gcacgacgcc ttcaaaagct
    12541 taataatgag caaaaaatgc aatccaatcg tttaaaaaca acgattgaaa atattccaag
    12601 tgctatttta atgatagatc gaaatggaaa aatcgttgtt gcaaataaag cgtattatga
    12661 acagttcaac atctcgcata atattgaaca agtaggctat cacggttatg ttaatactga
    12721 aattgagcaa ttaattttag aaagttttaa agttgaaaaa cctatttatg aacaattgga
    12781 agttgcaata aaccaagtcc atgccaagta ctttgatatt tcatgcgttc cgattttaac
    12841 taggtctcaa aaaagtttgc aagggatttt agttgtgatg catgacataa caaatctgaa
    12901 acaacttgaa aatctaagac gtgaatttgt agcaaatgtt tcacatgaat taaaaacacc
    12961 tattacttca attaaggggt ttgctgaaac gcttattgat ggtgcaaaaa atgatgcgga
    13021 atcattagac atgtttttaa acataatttt aaaagaatca aatcgaatag aatctttagt
    13081 aacagatctg ttagatttat cgcatattga gcaacataca gagttagata cagactatat
    13141 gaatttatca gatttaacgc ggcgtattat tgataatatg atgactcaag ccaatcaaaa
    13201 aaatatttcc attcatactg atattgaaaa agatgtcatt gttaaagcac aagaaagtaa
    13261 aattgctcaa gttatcacga atttgttaac gaatgcaatt aactattctt atgaagatgg
    13321 agatattaac gttcgtgtgt atcgagatga ctttcgtgtc attttcgaag tacaagattt
    13381 tggtataggt attaaattag aagaccaaca acgtattttt gaaagatttt atagagtaga
    13441 taaagcacga agtagagatt ctggtgggac aggtcttgga ttatcaatta caaagcatat
    13501 agtagaggcc caccaaggca atattgaaat gaatagtcaa gttggcaaag gctcaacgtt
    13561 caaagttatt ctaaaagatt ataaagaata aaaattaaag tggtaacagc gcgtgtattt
    13621 ttcacgaagt tgttgctgct tttttatttc gttcaaatct ctattggtat taaattagag
    13681 ttaatgaagt ggaataaatt cggttgtcaa ttttgtcatt tgcatatgtc gatttgtaag
    13741 ttataagtaa tagattgttg tgaatcaagc aattttataa tatatttatt ataataaaga
    13801 aattttagta acgcgcttaa aatagatgct taattaaaaa gtaataagtt ttatttgaac
    13861 ggaaataaat cttaatttaa acacttgaat agacaagtgt aatcattcgt catagaaaaa
    13921 gacgaggggc gatttagata aattgttgaa agtaatatta aataccttgt ttatctaatt
    13981 tgattgagga aacatgcata ggtgaaaatt agaaatacat taaaaatatt gaattaattt
    14041 ttcgacctac aagttgagga aaatttaact agatttgagg attagcaaag tgaaaacaat
    14101 tcaattacac aagacaactt tgatattaat tgcgatatta ttgttttata cttttatggg
    14161 tatcttacta ccactcatgc acgatgattt acaatggttt agcaattata atactgatat
    14221 tttaaaagta ggatttgcat cacttaatgg tcgctatatc ggaaatatct ttgaaattat
    14281 agctgtacat gtaagctggt tacgttggct ttcatatggt ctcattagta tgggcatcat
    14341 ttggatgatt atgcacatta cacgttgtaa agcgtggaca agctattatt tgttagcatt
    14401 ttctttaatg ttaattttac caagtgctat ttatgcagat acatatggct ggtttgcagg
    14461 attttataat tatgcgacat caacactaat ttcactcttt attatttatt attgtattaa
    14521 tgcaattata tataaagaaa agcagccggt aagtgttact gtactattct atgttttatg
    14581 cttcttcggt caattattta tggagaatgt gacattattc cactgtatca ttttaatttt
    14641 agcttttctg tatgaattta ctgcaaatcg aacacttaat tataaattat tgttttcatt
    14701 tatgattgct actataggta caatcattat gttttccaat ccaaattatc gcaaaatttt
    14761 atttgaagga tcagaatatc aacaagtttc aaataatcaa ggtatctttt caaaatttgc
    14821 agaaatgata tcaacgtcac ttccatatgg tgtcattttc agtcagatta taattttaag
    14881 tatgattgca gcgcttatta tttatctact gcttagaagt gatcggtatg tacatttaac
    14941 aatattaaag cgtcgtatca ttatgatagg atttatcact ttaccgcttt attatttact
    15001 attttacaat cagtttttat taaataaaaa tacagatatt ggattggttg gttttgtgaa
    15061 cgtaattgta tgtggttact ttgcgttttc gatatttgta ggtatttatt tgtctattaa
    15121 tgatcgtaaa acacaaatca ctttatattc cttacttatt gcaatatgtg tttcggcgtc
    15181 gacactagtc attgttactc caatagaacc aggtaatttt ttgattgttt atacgataca
    15241 tgtaatcatt ttaattattt tattaaaaga atttcggaaa tataagtcaa tcaatgttaa
    15301 ttttattaaa gttgcatcac tagttttagc tatgatatat cttagtgcat ttatttatgt
    15361 tcattatgaa catgaaaaaa gagttcagtt attaaaacaa caaattaaag atcatccacg
    15421 acaagaggtt tatacagtgg aatcattgcc gtttgaacat tatatgcatc atccgtcacc
    15481 aatcaataaa aattaccaag agtggtttaa taattatgaa gaattaccga aaatgaccaa
    15541 agttaaatat attccatttg gttctgacga ttcataactt attcttacct ataaaaattt
    15601 aaaatagcag cataaaaata ttaaaaagta gacataatca tgaaatgata atgtgcatct
    15661 caaaagttgg acttttaacc tgactttatg gagtgctaat caagaacaat catgattatg
    15721 tcatttttat tttttagctt agtctatata gtcacttgtt ttatttgaaa ttaggtcgtg
    15781 tataaatact ctatgagata gtttctttaa ttacgacatc acagtcgaat atgctaaaat
    15841 atatataaat tagttctgga ggttaaaatt gtgaataaat tagtattaat cgatggtaat
    15901 agcttaagtt ttagagcttt ttatgcatta cctttgttat caaacaaagc aggcattcat
    15961 accaatgcag tatatggttt tgcaatgtta ctagagaaga ttttaaaaga agaaaagcca
    16021 aatcattttt tagtagcgtt tgatgcaggt aaaacgactt tcagacatga aaaatatagt
    16081 gaatataaag gtggacgcca gaaaacgccg cctgaactaa gtgagcaatt tccttatata
    16141 cgccaattat tagatgcata tcatattaaa cgttatgaat tagataacta tgaggcagat
    16201 gatattatcg gaactttaag taaagaagca gataaagcgg gctttcagac aattattatt
    16261 acgggagacc gagatttaac acaacttgca acggataatg taaccattta ttacactaaa
    16321 aaaggtgtta ctgatgttga tcattataca cctgacttta ttgcggaaaa atacaacggg
    16381 ttaacaccta atcaaattat tgatatgaaa ggattaatgg gagatacttc tgataatata
    16441 ccaggtgttg caggtgttgg agagaaaaca gcaataaaat tgctaaacca atttgacaca
    16501 gtagaaggtg tctatgaaca tttagatgaa atttcaggta aaaagttaaa agagaaactt
    16561 caaaatagca aagaagatgc attaatgagt aaagaattag caacgattaa tgtagatagt
    16621 ccgattgaag taaaacttga agatacgtta atgactcatc aagatgaaca acaagaaaaa
    16681 atcgaattgt ttaagaagtt agaattcaaa caattgttgg ctgacattga tcaatcagca
    16741 agcgttgaag atgcaataga aaagacaatt gaaattgaaa cgtcttttga taatgttgat
    16801 tttacttcat tgaaagaagc ggccatccat ttcgaattag acggtggtaa ctatttgcga
    16861 aataatattt taaaattctc tttatttaca ggtgagaaac atattgtaat taatgcggat
    16921 gacataaata attatgccga actagtttca tggttagaaa atccgaatac gaaaaaagtc
    16981 gtatatgatg ctaaaaaaac atatgtagca tcacatagat tgggaattga tattcaaaat
    17041 atttctttcg atattatgtt ggccagttat ataattgatc catctcgtac gattagtgat
    17101 gttcaatcag ttgtttcatt gtacggtcaa agttttgtga aagacgatgt gagtatatat
    17161 ggaaaaggta agaaatttaa ggtacctgaa gatgatgttt taaatccata tgttgcttct
    17221 attactgatg caatttactt tgcgaaacca aatatggata aacaattaga agaatacaat
    17281 caggtagaac tcttagctga tttagagcta ccgctagcta agattttaag tgaaatggaa
    17341 gaaattggta tatttacaga tgttcatgat ttagaagaaa tggaaaaaga aattcaagaa
    17401 aaattagacg tcttgattcg aaatatccat gatgcagctg gtgaagattt taatataaat
    17461 tctcctaagc aattaggtgt tgtattgttt gagacattac aattacctgt tattaaaaag
    17521 acgaaaacag gatattctac tgctgtagat gtcttagagc aattgcaagg tgaacatcct
    17581 atcattgatt atattttaga atatcgtcaa ttatctaagt tacagtctac ttatgttgaa
    17641 ggattgcaaa aggtaattag tgatgatcaa cgtatccata cacgttttaa ccaaacttta
    17701 gcgcaaactg gacgtttatc aagtgtagat cctaatttac aaaatattcc ggttagactt
    17761 gaagaagggc gtaaaataag aaaagccttt aaaccaactt caaaagatag cgttatatta
    17821 tcagcagatt attctcaaat tgaattgcgt gtattagcac acattacaca agatgagagt
    17881 atgaaagaag catttatcaa cggcgatgat attcatacag caactgctat gaaagtattt
    17941 ggtgtagaag ctgatcaagt cgatagttta atgcgtcgtc aagcaaaagc ggttaacttt
    18001 ggaattgttt atgggataag tgattatggt ttaagtcaaa gtttaggtat tactcgtaaa
    18061 aaagcaaaag cattcattga tgattattta gctagtttcc caggtgtaaa acaatatatg
    18121 tctgatattg taaaagatgc caaagcttta ggttatgtgg aaacattgct acatcgtcga
    18181 cgctatattc ctgatattac gagtcgtaac tttaatttac gcggctttgc tgaacgtact
    18241 gctatgaata cgccaataca aggcagtgct gcagatatca ttaaactggc aatggttaaa
    18301 tttgcacaaa aaatgaaaga gacaacatat caagctaaac tattattaca agtacacgat
    18361 gaattaattt ttgaagtacc taagtcagaa gtagattcat ttagtgaatt tgtagaagag
    18421 ataatggaaa atgcattgca attagatgtt ccattaaaag tagactcaag ttatggtgca
    18481 acttggtatg atgcaaaata aagtgaggtt aatggtatgc ccgaattacc agaagtagaa
    18541 catgtaaaaa gaggaattga accctacgtt ataaatcaaa aaattgaaca cgttaaattt
    18601 tcggataaag taattgaagg taaagctcaa ggcaaggaaa caattataaa aggaattgaa
    18661 ttagatactt ttaaaacttt atcggaaggc tataccatta caaatgtaga acgaagaagt
    18721 aaatatatcg tttttcagct agataataaa cgagaacaac gtacattaat tagtcattta
    18781 ggtatggcgg gtggtttttt cattgtagat gaacttgaag atattatgat acctaattat
    18841 cgtaagcatt ggcatgttat ttttgagttg tcaaatgaca aaaagttaat ttattcagat
    18901 atacggcgtt ttggagaaat tagaaatgtt gcgtctgtag catcttaccc ttcattttta
    18961 gaaatagcgc ctgaaccttt ttcaaatgaa gcattgacgt attatttaaa tcgaattcat
    19021 caacagtcta ataagaataa accaatcaaa caagtgattt tggatcataa agtaatcgca
    19081 ggttgtggaa atatttacgc atgtgaagcg ttgtttcgtg caggtgtttt accagataaa
    19141 aaagtaaaag acttaacaca ccaacaacaa gaaatggttt tttattatgt tagagaagta
    19201 ctagaagaag gtattaaata tggcggtaca agtatttcag attatcgtca tgctgatgga
    19261 aaaactggtg agatgcaatt gcatcttaat gtatataagc agccggtatg caaagtgtgt
    19321 ggaagtcaaa ttgaaacaaa aatcatcgcg acaagaaata gtcattattg tccagtatgt
    19381 caaaaataaa gaaagagtga aattatgccg aaagttattg gtctaacagg tggaatcgcc
    19441 tcaggaaaat caacagtatc agaactctta tccgtattcg gttttaaagt agtagatgct
    19501 gataaagcag ccagggaagc tgttaaaaag gggagtaaag gtttagctca agtacgagaa
    19561 gtctttggtg atgaagcaat tgatgaaaat ggcgagatga atcgtcgtta tatgggtgat
    19621 ttagtgttta accatccaga aaaacgctta gaattaaatg ctatcataca tcctatcgtg
    19681 cgagatatta tggaagaaga aaagcaagaa tatttaaaac aaggatataa tgtaatcatg
    19741 gatattccat tattatttga aaatgaattg gaaaatacag tagacgaagt gtgggttgta
    19801 tacacttctg aaagtataca aatggatcgt ttaatgcaac gtaataattt gtcattagaa
    19861 gatgcgaaag ctcgtgtcta tagccaaatt tctattgata aaaaaagccg aatggccgat
    19921 catgttatcg ataatttagg ggataaactt gaattaaaac aaaaccttga gagattgtta
    19981 gaagaagaag gttatattga aaagccgaat tacggagaag aagattaata ttacactata
    20041 aataagtcat tactttacgt acgggttgat gtatgtaagt aatgactatt ttttataaaa
    20101 aagataaata aatcgacgga aaacgctttc aaatttcata taatatgcta tactaattcc
    20161 ataaagtata acacataaaa atcaaggggt gcttttaatg tcaacgaata ttgcaattaa
    20221 tggtatgggt agaattggaa gaatggtatt acgtattgca ttacaaaata aaaatttaaa
    20281 tgtagtagcg attaatgcta gttatccacc cgaaacaatt gcacatttaa tcaattacga
    20341 tacaacacat ggaaaatata atctaaaagt agaaccaatt gaaaacggat tgcaagttgg
    20401 tgatcataaa attaaattgg ttgctgatcg caatcctgaa aacttgccat ggaaagaatt
    20461 agatatcgat attgctatag atgcaactgg taaatttaat catggtgata aagccatcgc
    20521 acatattaaa gcaggtgcca aaaaagtatt gttaactggt ccttcaaaag gtggacatgt
    20581 tcaaatggta gttaaaggcg taaatgatga ccaattagat atagaagcat ttgacatttt
    20641 tagtaatgct tcatgtacta ctaattgcat tggtccagtt gcaaaagttt taaataatca
    20701 gtttggaata gttaatggtt taatgactac tgttcacgct attacaaatg accaaaaaaa
    20761 tattgataat ccacataaag atttaagacg tgcacgctca tgtaatgaaa gcattattcc
    20821 tacttctact ggtgcggcga aagctttaaa agaagtattg ccagaattag aaggtaaatt
    20881 acacggcatg gcattacgtg taccaacaaa gaatgtatcg ctcgttgatt tagttgttga
    20941 tttagaaaaa gaagtaacgg cagaagaagt aaaccaagct tttgaaaatg ctggtttaga
    21001 aggtatcata gaagtcgaac atcaaccact agtgtctgtt gatttcaata ctaatccaca
    21061 ttcagctatt attgatgcaa aatcaacaat ggtcatgtca gggaataaag taaaagttat
    21121 tgcttggtat gataatgaat ggggttattc aaatagagtt gtagatgttg ctgagcaaat
    21181 tggagcactt ttgacatcaa aagaaactgt aagtgcaagt taatacaatt atttaatagc
    21241 ctgactctga cttcggagtt aggtttttta tttttaatac aataatattg tcatgcatat
    21301 tacttaataa gtaacgatat aatgtttttt attgtttcat tatttggtta aatgaattaa
    21361 attgagggat tcttttttca tctctagatt tatagtataa ttaggcataa tcaaaataaa
    21421 gagggtgatg taatgaaatg cccgaaatgt aattctacac aatctaaagt tgtagattca
    21481 aggcatgccg atgaattaaa tgccattcga agacgaagag aatgtgaaaa ttgtggaaca
    21541 cgtttcacta catttgaaca tatcgaagtt agtcagctta tagttgtgaa aaaagatggc
    21601 acaagagagc agttttcaag agaaaagata cttaatggac ttgtgcgttc ttgtgagaaa
    21661 cgaccagtta gatatcaaca acttgaagac ataactaaca aggttgaatg gcaattacga
    21721 gatgaaggtc atacggaagt gtcttcacga gatataggtg aacacgttat gaacttgtta
    21781 atgcatgttg atcaagtttc atatgttaga tttgcatcag tctataaaga atttaaagat
    21841 gttgatcaat tgttagcatc gatgcaaggg attttaagcg aaaacaaacg gagtgatgct
    21901 taaatgggac gacaagcctt cgaattcggc ttaagaccaa aggatcaatt caaagttatg
    21961 caacactttg atttaaatac gaatcattta gaggtattga atcgactgta tacaccgcta
    22021 attggaacac aagcagtggg tttataccat tttatgacac aattcgttaa agaaagtcat
    22081 aatgaaacat tgattctttc tcattatatt tttatgaatg aacttaaaat taatttacta
    22141 gagtttagac aacaaatgga cttacttgaa gcgattggat tgttaaaggc gtttgtcaaa
    22201 catgatgaac aagaaacaca atttgtttac caattaattc aaccgccttc agcacattta
    22261 ttttttaatg atccaatgtt gtcaatcttt ttatatagtg aagtcgagca tcgtcgattt
    22321 catgagttga agaaatactt tgagtatcaa caaattgatt tgagtgaatt taaacaggta
    22381 acaagacaat ttactgatgt ttttaaagtg ccgtctacaa aaatagatat cgatacaagt
    22441 gatattccga ttaatgaacc gtaccaaggt atcgatttat caaatgaatc ttttgacttt
    22501 gaaatgttga gacaaatgtt aggtaaacat tttattagtc aagacattgt taccaaagat
    22561 gcaaagcgtt taattacaca actcgcgact ttatatggtt taacagcaga tggcatgaag
    22621 catgttattt taaattcaat tacaagtgga caacagttat cctttgaaga aatgcgtaaa
    22681 caagcacgct cgtattactt aatggaacac gaaaatcaaa tgcctaaatt acaggtgaaa
    22741 tctcctgtta catcatcttc gacgggcaaa tcttcagaag tgaatccaaa gccacaaagt
    22801 gatgaatggt ttgagttact tgaacaaacg agtccaattg atatgttagc ttcttggtct
    22861 gaatcagaac caactatatc gcaaaagaca atggttgaag aattaattga acgtgaaaaa
    22921 atgtcttttg gcgtcattaa tattttgttg caatttgtca tgttaaaaga agatatgaaa
    22981 cttcctaaag cgtatatttt ggaaatagca tcaaattgga agaaaaaagg tattaagaca
    23041 gctaaagaag catataatta cgctaaaaaa gttaatcaac ctaaaaatga gggttctagc
    23101 ggaaattacc aaaagcgtgg ttcatactat gggcagcgta atcgtatttc aaaagaaaaa
    23161 acacctaaat ggttagaaaa tagagataaa cctagtgaag aagattcggc taaagataat
    23221 agcgtagatg atcaacaatt agagcaagat cgacaagcat ttctagataa attatctaaa
    23281 aaatgggagg aggacagtca ataatgaagc aatttaaaag tataattaac acgtcgcagg
    23341 actttgaaaa aagaatagaa aagataaaaa aagaagtaat caatgaccca gatgttaagc
    23401 aatttttgga agcgcatcga gctgaattaa cgaatgctat gattgatgaa gacttaaatg
    23461 tgttacaaga gtataaagat caacaaaaac attatgacgg tcataaattt gctgattgtc
    23521 caaatttcgt aaaggggcat gtgcctgagt tatatgttga taataaccga attaaaatac
    23581 gctatttaca atgcccatgt aaaatcaagt acgacgaaga acgctttgaa gctgagctaa
    23641 ttacatctca tcatatgcaa cgagatactt taaatgccaa attgaaagat atttatatga
    23701 atcatcgaga ccgtcttgat gtagctatgg cagcagatga tatttgtaca gcaataacta
    23761 atggggaaca agtgaaaggc ctttaccttt atggtccatt tgggacaggt aaatctttta
    23821 ttctaggtgc aattgcgaat cagctcaaat ctaagaaggt acgttcgaca attatttatt
    23881 taccggaatt tattagaaca ttaaaaggtg gctttaaaga tggttctttt gaaaagaaat
    23941 tacatcgcgt aagagaagca aacattttaa tgcttgatga tattggggct gaagaagtga
    24001 ctccatgggt gagagatgag gtaattggac ctttgctaca ttatcgaatg gttcatgaat
    24061 taccaacatt ctttagttct aattttgact atagtgaatt ggaacatcat ttagcgatga
    24121 ctcgtgatgg tgaagagaag actaaagcag cacgtattat tgaacgtgtc aaatctttgt
    24181 caacaccata ctttttatca ggagaaaatt tcagaaacaa ttgaatttta aaatgattgg
    24241 tgtataatga atacaaatct aaatcgttta aatgattgaa gacaagatga tctaatcaat
    24301 attacacaga aagccattgt ttgatgagaa tatggttaat aaattaggtg attactactt
    24361 catttatggt atttgtaatg aatacccgga tcaagaccgt tatcttaagc agagatattt
    24421 aatacataaa ttgtattaaa taactagggt ggtaccacga cgatctcgtc ccttgtatag
    24481 gggcgggatt ttttgttttt ttcagacaaa aatgttcgtt ggtttcataa attccctgtt
    24541 tattgttaat aggtttaatg ttaaaacgat gattgttgtt caatttttta acgaggtcag
    24601 ataaaagtat ttataaagca aataggaggg tttaacatgg aacaaattaa tattcaattt
    24661 ccagatggta ataaaaaggc gtttgataaa ggtactacta ctgaagatat agcacaatca
    24721 attagtcctg gattacgtaa aaaagctgtt gccggcaaat ttaacgggca acttgtagat
    24781 ttaactaaac cgcttgaaac tgatggatca attgaaattg tgacaccagg tagtgaagaa
    24841 gcgttagagg tattacgtca ttctactgca catttaatgg cacacgcgat taaaaggtta
    24901 tatggtaatg ttaaatttgg tgtaggtcct gtaatagaag gtggattcta ctatgacttc
    24961 gacattgacc aaaacatctc atctgatgac tttgaacaaa ttgaaaaaac aatgaaacaa
    25021 atcgttaacg aaaatatgaa aatcgaacga aaagtggttt cacgagatga agcgaaagag
    25081 ttattcagca atgatgaata caaattagaa ttaatcgacg cgattcctga agatgaaaat
    25141 gtaacattat atagtcaagg tgattttact gatttatgtc gtggcgttca cgttccatca
    25201 acagctaaaa ttaaagagtt taaactatta tctacagcag gtgcatactg gcgtggagat
    25261 agtaacaaca aaatgttaca acgtatatac ggtactgctt tctttgataa aaaagaatta
    25321 aaagcacatt tacaaatgtt agaagagcgt aaagaacgtg atcatcgtaa aattggtaaa
    25381 gagttagaac tattcacaaa tagccaatta gttggtgctg gtttgccatt atggttacct
    25441 aacggtgcaa caattagacg tgaaattgaa cgttacattg ttgataaaga agttagcatg
    25501 ggatatgacc acgtttatac accagtactt gctaatgttg atttatacaa aacatctggt
    25561 cactgggatc actatcaaga agatatgttc ccaccaatgc agttagatga aacagaatct
    25621 atggtattac gtccaatgaa ctgtccacat catatgatga tttatgcgaa taaaccacat
    25681 tcatatcgtg aattacctat ccgtatcgct gagctaggaa cgatgcatag atatgaagca
    25741 agtggtgctg tatcaggatt acaacgtgtt cgtggtatga ctttaaatga ttcacatatc
    25801 tttgttcgac ctgatcaaat taaagaagaa ttcaaacgcg ttgtaaacat gattattgat
    25861 gtgtataaag actttggttt cgaggattat agctttagat taagttatag agaccctgaa
    25921 gataaagaaa agtactttga tgatgatgat atgtggaata aagctgaaaa tatgcttaaa
    25981 gaggcagcgg atgagcttgg cttatcgtac gaagaagcga ttggtgaagc ggcattctat
    26041 ggtccgaaac tagatgttca agttaaaaca gcgatgggta aagaagagac attatcaaca
    26101 gcacaacttg atttcttatt accagaacgt tttgatttaa cttatattgg tcaagatggt
    26161 gaacatcatc gtccagttgt tattcatcgt ggtgttgtat caacaatgga acgatttgta
    26221 gcatttttaa ctgaagaaac taaaggtgca ttcccaactt ggttagcgcc aaaacaagtt
    26281 caaatcattc cagttaacgt tgatttacat tatgattatg cgcgccaatt acaagatgaa
    26341 ttgaaatctc aaggcgttcg tgtaagtatt gatgaccgta atgaaaaaat gggttataaa
    26401 attagagaag ctcaaatgca aaaaatacct tatcaaatcg tagttgggga taaggaagtt
    26461 gaaaataatc aagtgaatgt gcgtcaatat ggatcgcaag accaagaaac agttgaaaaa
    26521 gatgaattta tctggaatct agttgatgaa attcgtttaa aaaaacatag atagacagtt
    26581 gtcgcaataa aatgctttga aatttttatt gcgtatcaag tttcacaggg ttgattatgc
    26641 gtgatgaatc ctgtatatta caagttagtt aaaatattaa attgagttag aggttgcatg
    26701 tttaattagt aacttgtcag aagtatttat ggtacataag ttgaacaagt gaaaggtaaa
    26761 gatgccgaaa tagatataaa ccataaatta tatctattgg gacagttttc gaataggaac
    26821 tgtactgtca cagaatgtga tgtgctacct tatatagata attgccaaag tggttgcata
    26881 tcttaaaggt atgtagccac ttttttactt ttaatatcac tatgttctgt aaaaaagggt
    26941 atgaaagtga ataaaggtta tttatttctt ggcctctaaa acatggaaag ggagcttata
    27001 tgtcaaaagt tcaaaatgaa agtaacaatg ttgtcaaaag gggacttaaa gatcgtcata
    27061 tttctatgat tgcgattggg ggttgtattg gtacaggttt atttgtaact tctggtggag
    27121 caattcatga tgcaggtgct ttgggtgcat taataggata cgcaattatc ggaataatgg
    27181 tatttttctt aatgacgtca cttggcgaaa tggctacgta tttgccagta tcaggttcat
    27241 ttagtacata tgctacaaga tttgttgatc catctttagg atttgcgctt ggctggaact
    27301 attggtttaa ctgggtagta actgtagcag cagatattac gattgcagca caagtcattc
    27361 aatattggac accattgcaa ggcatacccg cttgggcatg gagtgcgttg ttcttagtta
    27421 taatttttag tctgaattcg ttatcagttc gcgtctatgg tgaaagtgaa tactggttgg
    27481 cattgataaa agtggttaca gttattgttt tcattgcaat tggtttatta acgattgtcg
    27541 gaatcatggg tggtcatgtt gtaggattcg aaatatttaa taaaggtgaa ggtcctattc
    27601 ttggtggcaa tctaggcgga agtttgttat caattctagg tgtattctta atcgctggtt
    27661 tctcattcca aggtactgag ttaattggta ttacggctgg tgaatcagaa aatcctgaac
    27721 gtgctgtgcc gaaagcaatt aaacaagtat tctggagaat tttattattt tacattttag
    27781 ccatttttgt tatcggtatg ttaattcctt atgatagtag tgcattaatg ggtggtagtg
    27841 ataatgtagc aacgtctcca ttcacattag tgtttaaaaa tgctggattt gcgtttgcag
    27901 catcatttat gaatgcagtc attttaacgt ctgtgttatc agcaggtaac tcaggtatgt
    27961 atgcttcaac tcgaatgcta tattcaatga gtaaagataa attagcgttt gaagcatttg
    28021 gtaaaacaaa taaaaacggt gtgccatata tgtcgttact cgttacagca atcattgtag
    28081 tgattatttt cgtattacaa agccttacaa aaggtgcata cgaatatatc gttgcagcaa
    28141 gtggtttaac tggttttatt gcttgggtag gtatagcagt aagtcattat cgatttagaa
    28201 gagcatttga taaacaaaat tatgacaaat ctaaattaaa atatactgct aaattattcc
    28261 cattcggacc attatttgct ggctttttat gtattgtagt aattattggt caagatgttg
    28321 actttattaa aacaggagat tttaatttta gtcgcttctt aattacgtat atgggaattc
    28381 cagtattttt agcattcttt atttatcata agcttcgata taaaacgaaa aaaattccat
    28441 tagaacaagt agatttacgt caagacgtgt caatggatga aataaaaggt taaaataaaa
    28501 ataattacag ttatagtgtt gacttaaatg tgaattgttg atatgattaa caacgttgaa
    28561 tacgaaacga accaagtaga agcacccgct tctcacctgt agcgacgcat aaagcagttg
    28621 gcaggttaat cacattacac atatctgtgt ataaggaaga gcgggtattt tatacctgct
    28681 cttccttttt gcttggtgca aatttcgtaa aaattttgga ggtgtcaacc atagcaaaag
    28741 atcaaactca aatcaatgac aaaattcgtg caaaagaatt acgtttaatc ggtcaagatg
    28801 gtgaacaaat tggtgttaaa tcaaagcgag aagctttaga aatggctgaa cgtgtagatt
    28861 tagacttagt ggtcgttgca ccgaatgcga aaccaccagt tgcaagaatt atggattacg
    28921 gtaaattcaa attcgaacaa cagaaaaaag aaaaagaaat gaaaaagaaa caaaaaatta
    28981 tcaatgttaa agaaattcgt ttaagtccaa caattgagga acatgatttc caaactaagt
    29041 tgaaaaacgg acgtaaattc ttaactaaag gcgataaatg taaagtatct attcgtttca
    29101 gagggcgtgc cattacgcat aaggaaattg gtcaacgtgt gctagaaaaa tatgcagatg
    29161 aatgcaaaga tatagcaaca gttgaacaaa aacctaaaat ggacgggcgt caaatgttta
    29221 tcatgttagc gccaacagct gaaaaataat taaagctatt acaggaggac ttatattatg
    29281 ccaaaaatga aaactcaccg cggagcagct aaacgtgtta aaagaactgc ttcaggtcaa
    29341 ttaaaacgtt caagagcttt cacatctcac ttattcgcaa acaagagcac taaacaaaaa
    29401 cgtcaattac gtaaagctag attagtgtct aagagcgaca tgaaacgtgt aaaacaatta
    29461 ttagcataca aaaaataaga acaaatacag aaatcggtag gaattaccta aggaggaatt
    29521 ttttatgcca cgagttaaag gtggaacagt aacaagagcg cgtcgtaaaa aaacgattaa
    29581 attagctaaa ggttacttcg gttcaaaaca tacattatac aaagtagcta agcaacaagt
    29641 aatgaaatca ggtcaatacg ctttccgtga ccgtcgtcaa cgtaaacgtg acttccgtaa
    29701 attatggatt acacgtatca acgcagcagc tcgtcaacat gaaatgagct actcacgttt
    29761 aatgaacggt ttgaaaaaag ctggtatcga cattaaccgt aaaatgttat cagaaattgc
    29821 aatttctgat gaaaaagcat ttgctcaatt agtaactaaa gctaaagatg ctttaaaata
    29881 ataacactta taaaaaagag atggcattgt catctctttt ttatttttta aatagcaaaa
    29941 tgccacattt aatcgctaaa atatgacata tttgctaaaa tgcatttaag agaacaaaca
    30001 ttaaagtgag gagttttata cgatgtctaa atttgatgaa caaatcattg tagtacctag
    30061 agaaattatt tttaataatg aaaagaatac ttttaatggg tttttaaata agaataaacc
    30121 agaaggtcaa aatatttttg atgcgctaag tcaatatgaa gttaagcgac gcggcgatat
    30181 ggaagaggat ccatcatata aacaactcat ttcttattgt ttacttgaaa atgagcatgg
    30241 cgagatatta gtgtatgaac gattatctgg cggtggagaa gctcgattgc atggacaatc
    30301 ttcaataggt gtaggcggtc atatgaatga tgttccagga gcagaatcta ttaacgaagt
    30361 attgagagtt aatgctcaga gagaattaga agaagaagta ggtttaagtg agcaagattc
    30421 acaaaatatg gagtatatcg gttttattaa tgacgataat aatgaagtgg gcaaggtaca
    30481 tattggtgtt gtatttaaaa tcactgtaag tacgaatgat gtagaagcta aagaaacaga
    30541 tactttacga ataaaatggg ttgaaaaagg caacatagag tcatatgatg atttcgaaac
    30601 gtggagcgca ttaatccttc aagatttata atcaaacgag gtgacatata tgtcagatat
    30661 tattcagttt cctaactctt cgataaagtt atataaagat ataaaacgtg ctgaacaaga
    30721 ccaaaactat gacctgatgt atgaatatat tgtgcaatat gaacgtcaat ttgaactcac
    30781 tgaagaaata gcaatgatga aatgccgtat gttatatgag acggggtcat ttcttgaatt
    30841 aagagaagaa acaattgtct tattgaaaac tggcatacaa caatatgatg cattgatgat
    30901 ttattacgtg aaaagtttga ttggtttggg acaatatttt gaagcggtag aagtaattca
    30961 tcaaattatt gatgaagtca aagatcacaa aacaagaatg gcattacatc ctcttaaaga
    31021 atttgctaag tcaaaattaa ttgaagatga aaaacgattg actcagtcat taactgattt
    31081 tgatacgtta tcaatgaggg aacagacgca cttgattttg aagttaatag acattggtca
    31141 ttttcaattt caagaaacgg tattatatat attaaaatct aatacgtaca gttataacct
    31201 aattagttta atgattgagt atttaaggtt tgcaaattgt acacaagaac tgacaattga
    31261 aaagtatggt atggatgtaa cttttgtacc agctaattta aatgggctag aacatacaac
    31321 gctgaaagaa aaagttatac ctaacgttat ggaaacatta aatgatggtg ctttacatat
    31381 cgctgaagaa gcacaccata ttatgaataa tcactctatc atgatttatc caattgatat
    31441 tgaaactttg tttgaaacga ataaatggat taatgcatac gaatgttatt tcaaaaatat
    31501 gttaggactt aaatgtgaat tacaaagtat cgatgcattt aattttattc agcaattaga
    31561 tttgaataat aatagttaaa ttgttgcaaa ataatactca gcattttaat atagttttga
    31621 cgaaaaaagt tgatttacaa atatataaac gttgtgattt caatgtttgt atagggaata
    31681 gacctatgat ataataggga agttgaaaaa ataaattagt taatcatgga ggtatatata
    31741 catgacagca acttgggaaa aaaaggaagg taacgaaggt ttattaactg ttactgttcc
    31801 tgcagaaaaa gtaaacaaag cgttagatca agcattcaaa aaagtggtta aacaaattaa
    31861 cgtacctgga ttccgtaaag gtaaagtacc acgtccaatt ttcgaacaac gctttggtgt
    31921 agaagcatta tatcaagatg ctatcgacat tttattacca gatgcttatg gtgaagcaat
    31981 tgacgaaact gatattaaac cagttgcaca accagaagta agtgttactc aaattgaaaa
    32041 aggtaaagat tttatttttg aagcaacagt tacagttgag ccagaagtta aattaggaga
    32101 ctataaaggt cttgaaattg aaaaacaaga aactgaatta tctgatgatg agttacaaga
    32161 agcgattgac cacagcttag gacatttagc tgaaatggta gttaaagaag atggtgttgt
    32221 tgaaaatggc gacacagtta acatcgactt tagtggttca gttgacggag aagaattcga
    32281 aggtggacaa gctgaaggtt acgatttaga aatcggttca ggttcattca ttcctggttt
    32341 cgaagagcaa ttagaaggta tgaaagttga cgaagaaaaa gatgttgtcg taacattccc
    32401 agaagaatac catgctgaag aattagctgg taaagaagca acttttaaaa caaaagttaa
    32461 cgaaattaaa tttaaagaag ttccagaatt aacagatgaa attgctaatg aattagatgc
    32521 ggaagcaaat acagtagacg agtataaaga aaacttacgt aaacgtttag ctgaacaaaa
    32581 agctacagat gctgaaaatg ttgaaaaaga agaagcgatt acaaaagcta ctgataatac
    32641 aacaatcgat attcctgaag caatggttaa tactgaatta gatcgtatgg tgtctgaatt
    32701 tgcacaaaga attcaacaac aaggtttaga tttacaaacg tacttccaaa tctcaggtca
    32761 agatgaatct caattaagag agcaaatgaa agacgatgca gaacaacgtg ttaaaactaa
    32821 cttaacttta actgcgatcg ctgaagctga aaaaatcgaa gctactgatg aagatatcga
    32881 taaagaatta gaaaaaatga gtaaacaatt taatatctca gttgaagata tcaaaaatac
    32941 tttaggtaat actgatatca ttaaaaatga tgttcgtatc caaaaagtta tcgatttatt
    33001 aagagataac gcaaagttcg ttgaaggaac taaagaagat taatcttcat taaatattaa
    33061 attacaaaaa tgagtagcag atgcatagct tatgtatctg ctactattct ttaagcaaaa
    33121 agtttgtatg ttaatatgtt gcattgtaat atccaatcta gtatagtctt taacgaatag
    33181 gggtgtaaaa agaatgttta aattcaatga agatgaagaa aatttgaaat gctctttctg
    33241 cggaaaagac caagatcaag taaaaaaact tgtagcagga agtggtgtat atatttgtaa
    33301 tgagtgtatt gaattatgct cagaaatcgt cgaagaagaa ttagctcaaa atacttctga
    33361 agcgattaca gaattaccta ctcctaaaga aattatggat catttaaacg aatatgttat
    33421 tggtcaagaa aaagctaaaa aatctttagc tgtggctgtt tataaccact ataagcgtat
    33481 tcaacaatta ggaccaaaag aagatgatgt tgagttacaa aaaagtaaca ttgccttaat
    33541 tgggccaaca ggtagtggta aaacattatt agctcaaacc ttagccaaga cgttgaatgt
    33601 accatttgca attgcagatg cgacaagttt aactgaagct ggctatgtag gcgatgatgt
    33661 tgaaaatatc ttgttgagat taattcaagc agctgacttt gacattgata aagccgaaaa
    33721 aggtattatt tatgtagatg aaattgataa aattgcacgt aaatctgaaa acacatctat
    33781 aacacgtgac gtttcaggtg aaggtgttca acaagcattg cttaaaatct tagaaggcac
    33841 aactgcgagt gttccgccac aaggtggacg caaacatcca aaccaagaaa tgattcaaat
    33901 tgatacaaca aatatcttat ttattcttgg tggtgccttt gatggtattg aagaagtgat
    33961 taagcgccgt cttggtgaaa aagttattgg tttctcaagc aatgaagctg ataaatatga
    34021 cgaacaagca ttattagcac aaattcgccc agaagatttg caagcctatg gtttgattcc
    34081 tgaatttatc ggacgtgtgc caattgtagc taatttagaa acattagatg taactgcgtt
    34141 gaaaaacatc ttaacgcaac ctaaaaatgc acttgtgaaa caatatacta aaatgctgga
    34201 attagatgat gtggatttag agttcactga agaagcttta tcagcaatta gtgaaaaagc
    34261 aattgaaaga aaaacaggtg cgcgtggttt acgttcaatc atagaagaat cgttaatcga
    34321 tattatgttt gatgtgcctt ctaacgaaaa tgtaacgaag gtagttatta cagcacaaac
    34381 aattaatgaa gaaactgaac cagaactata cgacgcagaa ggtaatttaa ttaataatag
    34441 taaaacatca gcttaatcat tgatgtgtta taaaagtgaa aagctccaat caaagttgac
    34501 gctcaaatag tttaactttg atcggagctt ttttataatg tataccgaaa ggttcaaata
    34561 ttatataatg gtagagttga aagagaatat aaaaaagtga ggatataaaa tgaaagttaa
    34621 tcctaataat atagaattaa tcattagtgc agtaaaagaa gaacaatatc cagaaacaga
    34681 attgtctgaa gttgcactga gcggtcgatc taatgtaggt aagtctacat ttatcaatag
    34741 tatgattggc agaaaaaata tggcacgtac atcacagcaa cccggcaaaa cgcaaacgtt
    34801 aaatttttat aatatagatg aacaacttat ttttgtggat gttccagggt atggatatgc
    34861 taaagtaagt aaaacacaac gtgaaaaatt tgggaaaatg attgaggaat atataactaa
    34921 gagagagaat ttgcaattag ttattcaatt agttgattta agacatgatc caacacaaga
    34981 tgatatctta atgtacaatt atttgaagca ttttgatatt cctactttag ttatatgcac
    35041 taaagaagac aaaattccaa aaggtaaagt tcaaaagcat attaaaaata ttaagacaca
    35101 attagatatg gacccagacg atacaattgt aagttattca tcaattaaaa ataataaaca
    35161 acaacaaata tggaatttaa ttgaaccgta tatttcatag tttttgtacg acaaaactta
    35221 tacaaaaatt ttaaaaataa tgtaagcacg aaacttttaa ttagtacaca attgataaca
    35281 tttttcaacg ttcatcattt tgtcaaaaac tcaaaagtaa attagaaaga ttataattta
    35341 tttaagcatc gtacttaatt ggattttaaa ttatgttata atatttgtat tgttagtata
    35401 tatgggggcg tttcaaatgc attttattgc aattagtata aatcatcgca cagctgatgt
    35461 tgcactaaga gagcaagttg cttttagaga tgatgcctta cgaattgccc atgaagattt
    35521 atatgaaact aaatctattt tagaaaatgt catattatca acatgtaatc gaactgaagt
    35581 atatgctgtt gttgatcaaa ttcacacagg tcgttactat attcaacgat ttctagctcg
    35641 tgcatttgga tttgaagtag atgatattaa agcaatgtca gaagtaaaag tgggggacga
    35701 agcagtagaa catttattgc gtgtcacttc tggtttagat tcaatcgtac ttggagaaac
    35761 tcaaatttta ggtcaaataa gagatgcatt tttcttagcg caaagcacag gtacgacagg
    35821 aacaattttt aatcatctat ttaaacaggc aattactttt gcaaaaagag cacataatga
    35881 aacagatata gctgataatg ctgtaagtgt gtcttatgct gcggtcgagt tggcgaaaaa
    35941 agtatttggc aaattgaaaa gtaagcaagc tatcattatt ggtgcagggg aaatgagtga
    36001 attatcacta ttaaatcttc ttggttctgg aattactgat attacagtag taaatagaac
    36061 aattgaaaat gctatgaaat tagcagcaaa gcatcaagtg aaatatgatg aactatcatc
    36121 attaccaaat ttacttgaaa gtgcagatat tgtgattagt tcaacgagtg cacaatctta
    36181 tatcattaca aatgaaatga tagaaagaat tgcagaaaat agaaagcaag attcactagt
    36241 attgattgat attgcagttc ctcgagatat tgaacctggt attagtgcca tcacaaacat
    36301 ctttaattat gatgttgatg acttaaaagg tttagttgat gcaaacttac gtgagcgaca
    36361 attagcggct gcaacaattt cggaacaaat tcctgcagaa atacatgcac acaatgagtg
    36421 gattagtatg ttgggtgttg ttccagtgat tagagcttta cgtgaaaaag ctatgacaat
    36481 tcaagcagaa acgatggaca gtattgatcg taaattgcca gggttaagcg aaagagaacg
    36541 taaaattata tcaaaacata caaaaagtat catcaatcaa atgttgaaag atcctattaa
    36601 acaggccaaa gaattaagta gtgataagaa aagtaatgaa aaattagagc tatttcaaaa
    36661 tatatttgat atcgaagctg aatgtcctca tgagcaagcg aagcaacaaa aagaaagcaa
    36721 ggtcaaggaa atttcagcac gacgtatctt tagttttgaa taagcatatt aatatggtga
    36781 taatatgcaa gaaaacctgt ttattcgatt caatgaaatt atattattaa tatacttaat
    36841 cagtatcatt tgctattttt atgattttgt ccaaaaaagt cataagatta gaagtttagg
    36901 catatattta ttggggattg tttgggtttt acaaacaatc tctttatcta tttttattat
    36961 acaaactaga catattccat tagggtctat ttcagatgta ttctatactt taagttggct
    37021 gattatttca atctctttaa ttcttaacct tatcaaagtt ttgaatttct cagtgttttt
    37081 cttgaattta atagggctaa cacttttagg gatgaataca tttcaaccga cacattatac
    37141 taataaggtt cagaaaattg ctgttgtaga cgagttactg ttagtccata tcggtctagc
    37201 tgtgttaagt tatgtcttct ttgccttagc ttttgtcaat gcattactgt atatcatgca
    37261 ataccgtaat ttgaaggaaa agcgttttga tcaaaaatac tttagaatag gtagcgttgc
    37321 tacacttgaa tcaattgtgt tttactcaac gttaagtggg tggataattc tcatatttag
    37381 tattatttta ggtacacagt ggggtgtaat ttcagttggt gaacgtatat tcattgaccc
    37441 gaaggtaata ctctcttcaa ttattacagt attatatgga agttatattt tacttagaat
    37501 caacaaatgg ttgaattcaa gatatttaat atactataac attattttat tttgcttaaa
    37561 tatgattaat ttattttttg caacacattt tgtgaattga gaaaataatc tagagcaatc
    37621 cgttcctagg aggaattgaa catgcgtaaa ttagtcgttg gctccagaag aagtaaatta
    37681 gctttaacac aaagccagca atttattgat aaattaaaag ctgtcgagcc aaatctagaa
    37741 attgaaatta aagaaattgt cacgaaaggc gatcgtatag tagataaaca attgtctaaa
    37801 gtcggaggca aaggcttatt tgttaaagaa atacaacatg aactttttga aaaaaatatc
    37861 gatatggcaa tacactcact taaagacgta ccaagtgtaa ttccggaagg tttaacatta
    37921 ggttgtatcc ctgatagaga attacctttt gatgcgtata tttctaaaac acatacacca
    37981 ctatcccaat tgccagaagg cagtattatt ggtactagtt cattacgtcg tggtgcacaa
    38041 atattatcta agtatcctaa tttagagatt aaatggatta gaggtaatat agatacacga
    38101 ttagaaaagt tacaaactga agattatgat gcgattattt tagctgcagc tggtttaaga
    38161 agaatgggct ggtcagatga tattgtaaca tcttatcttg atagagatac attgttacct
    38221 gcaatcggac aaggtgcttt agggatagaa tgtcgtagtg acgatgaaga actattaaca
    38281 ttattaagca aagtacataa tgatgaagtt gcaaaatgtg tgactgctga acgaacgttt
    38341 ttagcagaaa tggatggtag ttgtcaggtg ccaattgcag gatatgctac aatctcagat
    38401 caaaaagaaa tcgaatttac aggtttaatt atgaccccag atggtaaaga acgatttgaa
    38461 tatacaatga acggaacaga tccggttgag ttaggcaaaa cagtgagtaa caaattaaaa
    38521 gagcaaggtg cttatgaaat tataaaacgc ttaaatgaac aacattaaat aatggagtga
    38581 cgtttaaata tgaagccagt tgtagttatg acacaaacaa atgacatgca aagtgattta
    38641 gtatcaatta ttcacaaacc ctttattgat ataaagccac taaattttga tattcatttg
    38701 ttaaatcaac gctatgactg gcttgttttt tcatctaaaa atgctgtgaa attcttttat
    38761 aaatatctaa aaggaattaa tgttgataac attgctgtga taggaagtaa gacagcgcaa
    38821 tattgtgaat cacttggcat tcgagttgat tttatgccaa acgacttttc tcaagaagga
    38881 tttttaaaat catttaatca aactaaccaa aaaatacttt tgccttcgag tgaattggcg
    38941 agaccattgt tattagcagc gttatctaaa aataatgaag ttgttaaaat agatttatat
    39001 acttcagtgc ctaacaaaca aaatatacaa gatgttaaag aaatgataga acatcaacaa
    39061 atcgatgcat taacattttc aagttcgtcg gcagtacgtt attattttaa tgaaggattt
    39121 gtaccaaaat tcaagtcgta ttttgctatt ggagaacaaa cagcacggac cattaaatca
    39181 tatcaacaac cagtaacaat tgcagaaatt caaacactcg aatcactaat tgaaaagatt
    39241 ttagaaagta ggggctaaaa atgaaatttg atagacatag aagattgaga tcatcagcga
    39301 caatgagaga tatggttaga gagaatcatg taagaaaaga agatttaata tatccaattt
    39361 ttgtagttga aaaagacgat gtgaaaaaag aaattaagtc attgccaggt gtataccaaa
    39421 tcagtttgaa tttacttgaa agtgaattaa aagaagctta tgacttaggc atacgtgcca
    39481 ttatgttttt cggtgttcca aactcaaaag atgatatagg tactggtgca tacattcacg
    39541 atggtgttat tcaacaggcg acacgtattg ctaaaaaaat gtatgatgac ttattaattg
    39601 ttgcagacac ttgtttatgt gaatatactg atcatggtca ttgtggtgtg attgatgacc
    39661 atacacatga cgttgacaat gataaatcat tgccactact tgttaaaaca gcaatttctc
    39721 aagtggaagc tggtgctgat attattgcgc caagtaatat gatggatggt tttgttgctg
    39781 aaattcgtcg tggattagat gaagccggct attacaatat tcctataatg agttatggtg
    39841 tcaagtatgc atcaagtttc tttggacctt ttagagatgc agcagattca gcgccatcat
    39901 ttggggatag aaaaacgtat cagatggacc ctgctaaccg tttggaagca cttcgtgaat
    39961 tagaaagtga tttaaaagaa gggtgcgaca tgatgattgt taaacctgct ctaagttatt
    40021 tagacatagt tcgagatgtt aaaaatcata cgaatgttcc agttgttgca tataatgtga
    40081 gtggagaata tagtatgact aaagcggcgg cacaaaatgg ttggatagat gaagaacgtg
    40141 tcgttatgga acaaatggtt tcaatgaaac gtgcaggtgc tgatatgatt attacgtatt
    40201 ttgcaaagga catttgtcgc tatttagata aataaggttt tatatgtatg attttccata
    40261 aactatagga ggaatttact ttatgagata tacgaaatca gaagaagcaa tgaaggttgc
    40321 tgaaacttta atgcctggtg gtgtaaatag tccagtacgc gcatttaaat cagtagatac
    40381 accagcaatt tttatggatc acggtaaagg ttcaaaaatt tatgatatcg atggtaacga
    40441 gtatatcgac tatgtactaa gttggggacc acttatttta ggacatagag accctcaagt
    40501 tattagtcat ttacatgaag caattgataa aggtacaagt tttggtgcat caacattact
    40561 tgaaaataaa ttggcgcagc tcgttattga ccgagtacct tcaatagaaa aagtgcgtat
    40621 ggtgtcatct ggtacagaag ctacattgga tactttaaga ttagcacgtg gttatactgg
    40681 cagaaataaa attgtgaaat ttgaaggttg ctatcatggt catagtgatt cgttattaat
    40741 caaagctggt tctggggtgg caacattagg attgccggat tctcctggtg tgcctgaagg
    40801 tattgctaaa aatacaatta cagttccata caatgattta gatgcactta aaatcgcttt
    40861 cgaaaaattt ggagacgata ttgctggggt aatcgtagaa cctgttgctg gtaatatggg
    40921 tgtcgtaccg ccgattgaag gttttttaca gggattaaga gatattacga ctgaatacgg
    40981 agcattgcta attttcgatg aagtaatgac tggtttcaga gtcggttatc attgtgcaca
    41041 aggtcacttt ggtgtgacac cagatttaac ttgcttagga aaagttatcg gtggaggact
    41101 acctgtaggt gcttttggtg gtaaaaaaga aatcatggat catatagcac cattaggaaa
    41161 tatttatcaa gcgggtacgt tatcaggaaa tcctcttgca atgacaagtg gttatgaaac
    41221 gttaagccaa ttaacgccag agacatatga gtattttaat atgttaggcg atatacttga
    41281 agacggttta aagcgtgtat ttgctaaaca caatgtacca ataactgtaa atagagcagg
    41341 ttcaatgatt ggttatttct taaatgaagg acctgtaact aattttgaac aagcgaataa
    41401 aagtgatttg aaattatttg cagaaatgta tcgagaaatg gcaaaagaag gtgtgttttt
    41461 accaccatct caatttgaag gtacattctt atctacggca cacacgaaag aagatattga
    41521 aaaaacgatt caagcatttg atacggcttt aagtcgtatt gtaaaataaa tatacggaca
    41581 aattgagagc ctgaactttg ttcaggctct ttttaaatgt atatcagaca tgggcggcga
    41641 cttgatagtg aaagtccata tatgctttgt agtcaaaact gctagcggat attgttatct
    41701 taacaaacgt gaagctcaag cagcaattta gtcattttat tttttattga aagaagtgga
    41761 aaacatgaca atgatatata gaaataattt cattgtgttc gttttatcat tttttattag
    41821 tattatattg tattcatcgc acgtattact cccatttatg tttggtccta ttatcgcatc
    41881 aatcatttgt gtgaaagttt tcaaacttga tattaaatgg ccattcttac ttagtgaatt
    41941 aggtattgta ctattaggtg tgcaaatcgg atcaacgttt acgaaaaatg tcgttatgga
    42001 tattaaagac aattggcttt cgattattgt tgtatctatt tcgatattat taattgcatt
    42061 agtaatggca tttattttta aaaaaattgc acgtattaat acagaaacag ctattttaag
    42121 tgttatacca ggagcactaa cacaaatgct ggtcatggct gaacaagaca aacgtgctaa
    42181 tttgttagtt gttagcttaa cgcaaacatc acgaattata tttgttgttg ttttagtacc
    42241 gttcatttca tatttttttc atgatggtaa catgcatgcg aatggaaagt taacaaaagt
    42301 cttgccttta tcacaagtat taaacatagg gcaaatagtt attttagcga tagctatctt
    42361 tatagtttat ctaattatgt ctaaaataaa gtttccaaca tttcaattat tagcaccact
    42421 cattgtatta attgtttgga atttttctac agatttaaca tttacactag atcattggtt
    42481 gttgaacatg gcacaactaa tatatatgat tagaattgga gttcaaattg cgcatttatt
    42541 gtcagattta aaaggtagac tagcaatcgc aattacaatt caaaatatta tgttgataat
    42601 tggtgcgcta atcatggttt atgttataca tttctttgat aataatccta ttaatgaatt
    42661 gtttcttggt gcagcaccag gaggggttaa tcagatagtt ttagttgcat tagctactgg
    42721 tgccgatgtt gctatgatta cgagttatca tattttccga atctttttca tcctatttat
    42781 tattgcacca ggaattaatt actttttaaa atatcgttcg aataagcgtg aagattagaa
    42841 actatcatcc atttaagttg aattatgctt aggatagaat tcattattaa ggtttaagca
    42901 aaggttgtac atctatattt agattaagat atctaatatt cgcagtgcat taacttggaa
    42961 ctttaactta tgatttgaat aaattttcac atcaaaaaac gagacagtct attagttaaa
    43021 aatagacgat gtctcgttta ttttatgatg ctatagcaaa ttaattgtgt ttaggctttg
    43081 atggacaatc ttttaaatgt gcatcatata aaccggctgc ttctaaaaac gaaaatactg
    43141 ttactggacc taaaaattta aacccgtatt gttttaaatc tttagatagt tgtgttgcag
    43201 tatcatcaac tgtgatacga tcagaagcat gttcatactg caaatcttta ggcttaccat
    43261 ttacatatga ccataaaaat ttactaaaac taccatatgc ttgttcaatt tttaaatacc
    43321 cttgagcttg attaacaatt gcttctaatt ttttacgatg atgaacgata tttggaaaag
    43381 tcattaagcg gtcgatatct tgagcggtca tttgcgctac cttttctggt tcgaaatcat
    43441 aaaatgcttc ttcataggct tctttctttt ttaaaatagt taaccaagat agcccagcat
    43501 gttgtgattc taatgctaaa agtttaaaca atgctttgct atcatagagc ggttgtcccc
    43561 atacataatc atgatagtct aagtagactg gatctttagt tccaaatgcg caatcattca
    43621 ttttattccc acctatacat tgacttattt tgtcaatcat tatactataa gttaagagtt
    43681 taatatatga tttgggaaga gtaagttcaa attattttaa agagagcata tgatttggtg
    43741 tgagtatgta aatgattttt actgaaggta gcccacagag tatcttagct gaacgtgatt
    43801 aatagtaggc taagacgtgt ttgagcgtta atcataatct agagtgcttg aagagatgaa
    43861 gcatttcaaa tttcacgatg atagtattgg tatgattatt ccaattatgt taaaagagtg
    43921 aatttgatat taatcatcct tcttgaatat aggtggtacc acggaatatc cgtcctattt
    43981 gtatatagga tggatatttt ttattttttt aggaggtata gcaaatggaa atgaaaccaa
    44041 aatatgatcc tcgtgaagtt gaagcgggac gttatgaaga atgggtaaag aatggttatt
    44101 ttaaaccgtc agaagataaa tcaaaagaaa catatacaat cgttatcccg ccaccaaatg
    44161 taactggtaa attacattta ggacatgcat gggatacaac tttacaagat atcattacac
    44221 gtatgaaacg tatgcaaggg tacgatacgt tatacttacc aggtatggat catgctggta
    44281 ttgcgacaca ggcaaaggta gaagctaaat taaatgaaca aggaataact agatatgatc
    44341 ttggtcgtga aaagttttta gaacaggcat gggattggaa agaagagtat gcgtcattta
    44401 ttcgtgcgca atgggctaaa ttaggtctag gtttagatta tagtagagaa cgttttactt
    44461 tagatgaagg tttaagtaaa gcagttaaaa aagtttttgt tgatttatac aataaaggaa
    44521 ttatttatcg tggcgaacgt attataaatt gggatcctaa agcacgtaca gctttatctg
    44581 atattgaagt aatacatgaa gatgttcaag gtgcgtttta tcattttaaa tatccttacg
    44641 ctgatggtga aggttttatt gaaattgcaa caacaagacc agaaacgatg ttaggtgata
    44701 cagcgattgt tgttaaccct aatgacgaac gatacaaaga tgtaatcggt aaaactgtta
    44761 tattaccaat cgtaggacgc gaactgccta ttttagcaga tgagtatgtt gatatagact
    44821 tcggttctgg tgctatgaaa gtgacaccag cacatgaccc taatgatttt gaaattggtc
    44881 aaagacatca attagaaaat attatcgtta tggatgaaaa tggtaaaatg aacgacaaag
    44941 ctggtaaata cgaaggtatg gaccgttttg attgtcgtaa acagctagtt gaagatttaa
    45001 aagaacaaga tttagttatc aagattgaag atcatgttca ttctgtaggt cattcagaac
    45061 gatctggcgc tgttgttgaa ccatatttat caacacaatg gtttgtgcgc atggaagact
    45121 tagcgaaacg ttcattagat aaccaaaaaa cagatgatcg tattgatttt tatccgcaac
    45181 gtttcgaaca tacatttaac caatggatgg aaaatattag agactggacg atttcaagac
    45241 aattatggtg gggtcatcaa attccggctt ggtatcataa agaaacaggc gaaatatatg
    45301 ttggagaaga agcgccaact gatattgaaa attggcaaca agatgaagat gtattagata
    45361 cgtggttctc aagtgcttta tggcctttct ctacgttagg ttggcctgat ttagaaagtg
    45421 aagactttaa acgatactac ccaacaaatg ccttagttac aggttacgat attatcttct
    45481 tctgggtagc acgcatgata ttccaaggct tagaatttac agatcgtcgt ccatttaatg
    45541 atgtattatt acacggttta gttcgtgctg aagacgggcg taagatgagt aaatcattag
    45601 gtaatggtgt ggatccaatg gatgttattg acgaatacgg tgctgatagc ttgcgttact
    45661 tcttagcaac gggttcatct ccaggacatg atttaagata ctcaactgaa aaagttgagt
    45721 cagtgtggaa ctttatcaat aaaatctgga atggggcacg tttcagttta atgaatatcg
    45781 gtgaagactt taaagttgaa gatatcgatt taagtggtaa cttatcatta gcagataaat
    45841 ggattctaac acgtttaaat gaaacgattg caacagttac tgatctaagt gacaaatatg
    45901 aattcggcga agttggacgt gcattatata atttcatttg ggatgatttc tgtgattggt
    45961 acattgaaat gagtaaaatt ccaatgaatg gtaatgatga agaacaaaaa caagttacac
    46021 gttcagtatt gagttatact ttagacaata ttatgagaat gctacatcca ttcatgccat
    46081 ttgtaacaga gaaaatatgg caaagtttac cacatgaagg tgacacaatt gttaaagctt
    46141 catggccaga agtgcgtgaa tcattgattt ttgaagaaag taaacaaaca atgcaacaac
    46201 ttgttgaaat cattaaatct gtaagacaat cacgtgtaga agtaaatacg ccattgtcta
    46261 aagaaatacc tattttaatt caagctaaag ataaagaaat tgaaacaact ttatcacaaa
    46321 acaaagatta tttaatcaaa ttctgtaatc ctagtacctt aaatattagc actgacgtgg
    46381 aaattcctga gaaagcaatg acatcagttg taattgcagg taaagtggta ttaccattag
    46441 aagggctaat tgatatggat aaggaaatca gccgtttgga aaaagaatta gctaaacttc
    46501 aaagcgaatt agatagagta gataaaaagc tctctaatga aaactttgta agtaaagcac
    46561 ctgaaaaggt tataaatgaa gaaaaacgta aaaaacaaga ttatcaagaa aaatatgatg
    46621 gtgtgaaggc aagaattgaa caattaaaag cataggagtt agtaacaatg aattacctag
    46681 agagcttgta ttggatacac gaaagaacta aatttggcat caaaccaggt gttaaacgta
    46741 tggaatggat gctagcacaa tttaataatc ctcaaaataa cattaagggt attcatgtag
    46801 gtggcacaaa tggtaaagga tctacagttg cttaccttag aacagcttta gttgaaaatg
    46861 gttatgaagt aggtacattt acgtcgccgt ttattgaaac atttaatgaa cgaattagtc
    46921 taaatggtgt gccaatatca aatgacgcta ttgtagaatt agtatcacgt attaaaccag
    46981 taagtgaaat gatggaacgt gaaacagatt taggtgttgc aactgaattc gaaataatca
    47041 cagcgatgat gtttttatat tttggtgaaa tacatcctgt tgattttgtc attgttgagg
    47101 ctggattggg tataaagaac gattcgacaa atgtctttac accggtttta tcaatcttaa
    47161 ctagtatcgg tctagaccat acagatattt taggtggtac gtatctagat attgctaggg
    47221 ataaaggcgc gattataaag cctaacgttc cagtgatata tgctgttaaa aatgaagatg
    47281 cattaaaata tgttcgtgaa cgcgcaattg aacaacatgc aaagccaatt gaattagata
    47341 gagaaattgt tgttgtatcg caaaatgatg aatttactta ccgttataaa gattatgaat
    47401 tagaaacaat cattttaagt atgttaggtg aacatcagaa acaaaatgct gcattagcca
    47461 taacagctct tattgaatta aatgaacaag gattaattga attagatttc aataagatga
    47521 tagacggtat tgaatcagtt cgttggactg gacgtattga gcaggtgcat gacaaacctt
    47581 taatcatttt ggatggcgca cataattcag agagtataga tgctctaatt gatacaatta
    47641 aacagtacca tgataaagaa aaagtagata ttttgttctc agcaataaac ggaaaaccga
    47701 ttaacgagat ggtcaaacat ttaagtttaa ttgcgcatac gttttatgca actgaatttg
    47761 attttccgaa agcgttacgc aaagaagaaa ttgtaggtag tattgaaaat gatgaaatac
    47821 aattagtaga tgactacgtt gaatttataa aaaattatca aggtgataca ttagtaatta
    47881 ccggtagtct gtatttcata agtgaagtta aatcaaaatt agactttgaa gcattataaa
    47941 actaaaacta aaatagccat gaagaatcta tttaatcaat aggtagagct tcatggttat
    48001 tttttatgct ctaaatcgta tgtgtttata aggttcaatt tcttgccatt attaattttg
    48061 ccgagcagta atgggctgtt aaagtatcca tcaattatgc ttagcaatat tgaaaaattt
    48121 aaatgaaaaa gcgattcaat tcttgaaaaa tagtgtatat ttacattttg ataataacta
    48181 actataattt acataaggag gttgtcattt ggtagtattg ttatcttata gttgcagttg
    48241 tatctttagt tttctatatc aatttatatc tatagaagaa acgtcatttg attatttaca
    48301 tagaagatcg aaatgtgatt attgtaattc atcactcaaa tggtatgaat taatgccgat
    48361 tattagtttt ttattattaa aagggcgatg tcgaaactgt cgaaagcgta tttccctaac
    48421 acatttctta ggggaaacct ttgctataat acctatcgtc tttattaagt atgatttcac
    48481 atacgtaaat gctacgctat ttataactac atatgttttt ctgcttattt ttactatgac
    48541 cgatatcact tctttaatgt tagattgtcg cttaattata atttattgta tcgtttctct
    48601 ctcgttaagt atgatttatc cagtagcttt tatcattatt agtatgacca cgcatatatt
    48661 ctacttttta tttcgggcat atattggtta tggtgacgtt ttactaatat ctgcactttc
    48721 tttgtttttc cctctccaat tcactattta tgtcatttta tttacatttg tcattgctgg
    48781 tttagttgct ttaattacca tgatatttaa gccgattaaa ctattacccc ttgttccatt
    48841 tatatttatt tcatttttta tcaattcact tttttataat gatatccatc aatttttagg
    48901 aggcgtatat ttttgaaaat taaagaaatg gtaacttcag aaatgccaag agaacgtttg
    48961 ttaagccatg gtgcaaaaag tctttcgaat acagaattat tagctatatt aattaacacc
    49021 ggaagaaaag gattctcgag catagacatt agtaatgaac tgcttaaatc tgcttcgaat
    49081 ctgaatgaat tgaaaaaatc ttcaattaac gatttgatac aagttaaagg gattggatta
    49141 caaaaagcaa ttactttaaa agcagcattt gagctagggg aaaggatggg gagaagagct
    49201 gaaaataatc gtataaaaat aacgcaacca agtgatgttg ctgattatat gattccaaca
    49261 atgaaagatt taacacaaga acattttgtc attttattgt taaattcaaa aaatgtagtg
    49321 attaaagaaa cctgtgtttt taaaggtaca ttaaatagtt cgattgtaca tccacgtgaa
    49381 atttttagta ttgcggtgag agaaaatgcc aatgcaatca tcgcagttca taatcatcca
    49441 tccggtgatg taacgccctc acaagaagat atcataacaa caatgaggtt gaaggagtgt
    49501 ggtttgattt tagggataga tttattggat catattataa tcggtgataa tagatttacg
    49561 agtcttgtag aagcgggtta ctttgatgaa aatgattgaa gttgatagaa ttaatgacgt
    49621 atcttgtgta taatacctac gaagtacttt cattggagga aaaatagtga ctctatttat
    49681 tattatcggg gttctcgtgc caatggttta taccatgcag ttaaatatta aaaatgaacc
    49741 tgtaacaaag cgcaatctat taataacatt agctttatct acgttaggta ttttagtaac
    49801 ggcattagca ggtgtgattg ttacaaaaca agcttttcct ttattaagtg tagcaatagg
    49861 ctcaattttt acaggaatcg tttggggcct tttactaagc ggtagctatg cgctgatacg
    49921 atttttatct aacgcatttg ggcgtaagta atagtaatct gttcatcaag tagtatacgt
    49981 gcttgaaaac aaattaaaac tcctaatgtg gaactagtta aaaaattcta aactagtaca
    50041 ttaggagttt tgttatgcag aataaattta attgttaaat tgaaagtgtg gtaaaaaccc
    50101 actatttatt tgaaaaaaat cgagcaacca tattaaacct tgatatccta agtaaataca
    50161 taataaaaca agtccgacat aaattaaaaa tcgcaaaata gaaagtccaa ctctaaaaag
    50221 gaggatgact aatagtgcta ttaaaataat tgttagtata ctcaatgcta caaacctcct
    50281 catatgcttt taaatcataa caaaattata agctatttta aatgaacgtg catcagtcct
    50341 aagatatatc atgattaagg ctgaagactg aggaaaatat acataataaa atatataatt
    50401 agatgaagac attggaggcg aactatgaga ttgatattta gtatgattaa aaacattata
    50461 gcagtaatag caattgtgat aattgtttat atcgccttga aatacgcacc ttttttaaaa
    50521 gaacaagatt ggaatcctgt aaatcacgat aatgatcaaa tgaatcaagt tacgcaaccc
    50581 actaatgatg cccaacatgt ttatgtaagt ggtgagaaat attcattaaa agaaaatgat
    50641 ttaataaaga atgtaccatt aagccaaatt aaaaatgtat ttaaaatgat agataaacaa
    50701 gagtttatgg ctgtgtctgg aatgaatcgc atggcttata atgatcaata tattataggt
    50761 caaagaggag acgaatttat tctttataaa tttggagatg agtcaatgcg tgtttacaat
    50821 actgaatttg aaatgcaaca agacttaaat gaattagggc aaaatttaca actaaaaccc
    50881 gaaaatgctt atcaatagga aattattgca taagaaatat attttagtta tcctgtcact
    50941 agaataaatt taaaaggttg gtgtagttca aatggcagaa caatcaaaac agaaacaagc
    51001 taatgaacaa caaaaggccc agaacttatt cgcacgttgg agacaacttc agaattcgaa
    51061 cagtgaatcc tcgaacgata caaacaaata attttaaaat ttaaatcgat tatttaaact
    51121 actagtgact ggaatgtttg ctagtagttt ttttgctttt aaaatgccac aaatttttta
    51181 cggagttgtt cattttcaaa ctaattcgta gttagtgctt tatttcataa tgggagtaat
    51241 ataaaataga aaaggatata caatattttg acataataga ggtgttctgg gtgcttaagt
    51301 tttttaaaaa taacaaatta attgttgttt tatgtgcaat tatcgttttt attgcattaa
    51361 ttgggctgtc catacgttca caatctcaat cacctcctga acaatatata ggtgattctg
    51421 tgtcttttgg acaacgagtt gtgagttatc cagttaattt tgttgctggt acgattgggg
    51481 acttttttaa aaaaggagat tctaaagaat ctaaaaataa gattagccag ttagaatcta
    51541 agaaccaaca attagaagcg gaaaatgaaa aattaaaaaa agagcttgat ttaaaagata
    51601 tttcaaaatt tgatcctatt tctactacgg ttttagcaag aaatccggat cagtggatga
    51661 atacaattgt tattgataag ggatctaaat caggtataac ttcaaatatg gctgtgatga
    51721 catcaaaagg ttttgttgga agagttacta aagttaataa attttcttca caagttgatt
    51781 taatctcaac taatacacgt gcgggtaaat tatctgtaaa tatacaacac ggctctaaaa
    51841 atatatttgg cttaattgat cgttatgatg aaaagaactc agaacttgta attagtgata
    51901 ttaataatag agataatatc tcaaaaggtg ataaagtcgt tacaagtgga ttagctgatc
    51961 aattaccaag taatttatat ataggagaag tgactaaggt tcaaaatgat caatatggct
    52021 tagctaaaga agttagggtt aagactggtg cagacttaac agatttgagt catgtttatg
    52081 ttgcaaaaag agatcctaaa acaattcctg atgatgaaag cagggataaa taatgcgtac
    52141 actgtattat tttttgatag gtattttact attttatata gatactgcaa ttgggcttct
    52201 tattccaatg aacataggta agtttgaact tgtatttgta ccacacctta catttatgta
    52261 tattttaatg atggtagtgt atcgtggctt tggcgtatca ttattgctca gcatattttt
    52321 aggcgtaatg actgatgtat actttggtag tatttatgga gtgtacttat ttggctatat
    52381 attgttttta gcacttatag atcgattctt taaaattttt tacaaagatc attcgatgtt
    52441 attcattatt atattagcca gcaccttatt attagaagtc tatgtggcat taatatacgg
    52501 tatgttagga ttcattcaat ttgatattat tcattttgta gtctttagat tattgccaac
    52561 attaattatg aattttgtac tgttgattat gctttatccg ttgattataa agttccttaa
    52621 aaaaacaaac aatgacattg acatgaaacg tcgtcaatgg taagatgcaa tagttgagta
    52681 gttataagta gctacataca accgctcaaa tataggttca agaacatttt taatgaagaa
    52741 agcgattttc aatcaaggcg ttgaaggaag aaacgagaag agtttatctt tataaatgac
    52801 tcgagttacg accgaaacaa cgtagagtgc aaacgcttga ctcaataacg aaatgtcacc
    52861 tatgtatggc gtgacttatt atacaggagg tgcaaagtat gtttgctatt attgaaacag
    52921 gtggaaaaca aatcaaagta gaagaaggtc aagaaatctt cgttgaaaaa ttagacgtaa
    52981 acgaaggaga tacttttaca tttgataaag tattatttgt aggtggagat tcagttaaag
    53041 ttggagcgcc aacagttgaa ggtgcaacag ttactgctac tgttaataaa caaggtcgcg
    53101 gtaaaaaaat tactgtattc acatacaaac gtcgtaaaaa ttcaaaacgt aaaaaaggcc
    53161 atcgtcaacc atacactaaa ttaacaatcg ataaaatcaa cgcgtaatta ttatgattac
    53221 tgttgatatt acagttaatg atgaaggcaa agtaacagac gttattatgg atggccatgc
    53281 tgaccatggt gaatatggtc atgatatcgt ttgtgctgga gcttcagctg tattgtttgg
    53341 tagtgttaat gcgattatag gattgacatc tgagagacca gatatcaatt atgacgacaa
    53401 tggtggtcat tttcatataa gaagcgttga tacaaataac gatgaagcgc aactaattct
    53461 tcaaacaatg cttgtgtctt tacaaactat tgaagaagaa tataatgaga atattagatt
    53521 aaattataag tgaggtgcat tccgatgtta aaattaaact tacaattctt cgcatctaaa
    53581 aaaggggtaa gttctacaaa aaacggacgt gactctgaat caaaacgctt aggtgctaaa
    53641 cgtgctgacg gtcaattcgt aacaggtggt tcaattttat atcgccaacg tggtactaaa
    53701 atttaccctg gtgaaaatgt aggtcgtggt ggcgatgata cattattcgc taaaatcgac
    53761 ggcgttgtta aattcgaacg taaaggtcgc gacaaaaaac aagtttctgt atatgcagta
    53821 gctgaataat tttgtctagt taacaccaga agtgaatctt ctggtgtttt ttacttttta
    53881 taaaacgttt ttcattatta ttttcatttt gttattaaaa aatgggaatt ttagacgtta
    53941 tactaaatgt gcgactgcat aagagcccct aatcgctaaa ctataagggg ctctaatatg
    54001 ctataattat tgggaaaatg aaaattatat gtaaaagagg tgagatatat gtttgtcgat
    54061 caagtcaaaa tatctcttaa agccggtgat ggtggtaatg gtattaccgc atacagaaga
    54121 gaaaaatatg taccatttgg tggaccagct ggcggtgacg gtggtaaagg tgcttcagtc
    54181 gtatttgaag tggatgaagg tttaagaacg ttattagatt ttagatatca acgtcatttt
    54241 aaagcaagca aaggtgaaaa tggccaaagt agtaatatgc atggtaaaaa tgcggaagat
    54301 ttagtattaa aagttccacc tggtacaatt attaaaaatg ttgaaacaga cgaagtgtta
    54361 gcagatcttg ttgaagatgg tcaaagagct gtagtagcga agggcggtcg aggtggccga
    54421 ggtaattcac gttttgcaac acctagaaac cctgcacctg acttcagtga aaaaggtgaa
    54481 ccaggcgagg aattagatgt atctttagaa ttgaaattat tagctgatgt aggattagta
    54541 ggtttcccta gtgtgggtaa atcgacttta ttatctatcg tttcaaaagc taagcctaaa
    54601 attggggcat atcattttac aacgattaaa ccaaatctag gtgttgtttc aacacctgat
    54661 caacgtagtt ttgttatggc agatttacca ggtttaattg aaggtgcatc tgatggcgtt
    54721 ggattaggac atcaattttt aagacatgta gagagaacaa aagttattgt tcacatgatt
    54781 gatatgagcg gttctgaagg tagagaacct attgaagatt ataaagtcat taatcaagaa
    54841 ttagctgcgt acgagcaacg tttagaagat agacctcaaa tcgtagtagc taacaagatg
    54901 gatttacctg aatcacaaga taatttaaac ttgtttaaag aagaaattgg cgaagatgtg
    54961 ccagttattc cagtttcaac aataacgcgt gataatattg atcaattatt atatgcaata
    55021 gcagataaat tagaagaata taaagatgtt gacttcacag ttgaagaaga ggagtcagtt
    55081 ggcattaacc gagtattata taaacataca ccgtcacaag ataaatttac aatttcaaga
    55141 gatgatgatg gtgcttatgt ggtaagtggt aatgctattg aaagaatgtt taaaatgact
    55201 gactttaaca gtgatccagc agtacgtcga tttgctcgtc aaatgcgttc gatgggtatt
    55261 gatgatgcac ttagagaacg tggttgtaaa aatggtgata tcgttagaat tcttggcgga
    55321 gaatttgaat tcgttgaata ggagcgtaac atgatggaca ataaagatta taaaaagttt
    55381 tatttaatta gagaagatgt cttgcctgaa tccgtggtta aaacattgaa gattaaagat
    55441 gccttaaaaa gtgatccgac attgtccatt tatgatgccg ttaaacagtt tgatctatct
    55501 agaagtgctt tttataaata tagagaaacg atatttccag tagacgataa aatgcttgac
    55561 catcgagaat ttacattaat tttatatgta acagatattg tgggtatgtt ggcacgtgta
    55621 ctagatgtta tatcaaagtt agaactatct gtattaacga ttcatcaaag tattccaatg
    55681 gaagaaaaag caacaataac attatcactg aatgctaaat ctaaagaaac tgcagtagaa
    55741 gatgttattg gcgctttgag aaatttagat tatgtatcaa aagtagaatt aattagtatg
    55801 agtatgtaag gatgtgccta taatgtacgc gtatgtcaaa ggtaagttaa cacatttata
    55861 tcctacacac gtagttgttg aaactgctgg tgttggttat gaaattcaaa caccaaattc
    55921 ttatcgtttt caaaagcaac tagatcatga agttttaatt catacatctt taattgttcg
    55981 tgaagatgca caattattgt atggatttag tagtgaagaa gagaaagata tgttcttgag
    56041 tttaattaaa gttactggta ttggtccgaa atcagcttta gctattttag cgacaagtac
    56101 gcctaatgaa gtaaaacgtg ccattgaaaa tgaaaatgat acgtatttaa ctaaattccc
    56161 aggaattggt aagaaaacgg caagacagat tgtcttagat ttaaaaggta aagtgaaaat
    56221 cactgaagaa gatagcgatt cattattaca agtagacgct acttcgacgg tgcaagatca
    56281 attcgtgcaa gaagcaatgt tagcgttaga agcattaggt tattctaaac gagagcttgc
    56341 aaaagttgag aaaacgttaa ataaaaataa atatgactca gttgatgaag ctgttaaggc
    56401 aggtcttcaa ttagttgtat cttaatttta aatagattaa taggggaagt gttgtcatga
    56461 atgagcgtat ggttgatcaa tcaatgcata gtgaagaaac tgatttcgaa ttgtcgctta
    56521 gacctacgag attacgacaa tatattggtc aaaattcaat aaaaagtaat ttagaagtat
    56581 ttattaaagc ggctaaactt cgtcatgaac cattagatca tgtattgctt tttggccccc
    56641 ctggattagg taagacaaca ttatctaata tcattgccaa tgaaatggaa gttaatatac
    56701 gtacagtatc agggccttca ttagaaagac ctggtgattt ggctgcaatt ttatcaggac
    56761 ttcaacctgg agatgttttg tttattgatg aaatacacag actgagtagt gttgttgaag
    56821 aagtgttata ccctgcaatg gaagatttct ttttagatat tatcattggt aaaggcgatg
    56881 aggctagaag tatccgtatc gacttacctc cattcacttt ggtaggtgca acaacgcgag
    56941 ctggcagctt aacaggtcca ctaagggatc gatttggtgt gcacttaaga ttagaatatt
    57001 ataatgaatc agatttaaaa gaaatcatta ttagaacagc tgaggtttta ggcacaggta
    57061 ttgatgaaga aagtgccatt gaacttgcta aacgttctag agggactcca agagtagcaa
    57121 atcgactatt gaagcgggta agagacttcc agcaagtgaa tgaagatgaa caaatataca
    57181 ttgaaacaac gaagcacgca ttaggtttac ttcaagttga tcaacacgga ctagattaca
    57241 ttgatcataa aatgatgaac tgtattatta agcagtataa tggtggacct gttggtttag
    57301 atacgattgc cgtaacaatt ggtgaagaac gtattacaat tgaggacgtt tatgagccat
    57361 ttcttattca gaaaggcttt ttagaacgta cgccacgtgg cagaaaagca acaccattag
    57421 cttatgaaca ttttgcaaag tcgaatgagg agagagaata acgtgaattt tgaagaattt
    57481 gactatgact taccagaatc attaattgct caaacgcctt taaaagatcg tgatcatagt
    57541 cgtttattag tcatggatag agaaactggt gaaatgaaac atttacattt caaagatatc
    57601 attgagtatt ttagacctgg tgatacatta gtgcttaacg atacgcgagt aatgccagct
    57661 agactttttg gtttaaaaga agaaactggt gcaaaagttg aaatgttaat gttaactcaa
    57721 attgaaggta atgattggga agtcttactg aaaccagcta agcgtattaa agttggtaat
    57781 aaattgaatt ttggtaatgg caaaattata gctgaatgca taaaagaaat ggatcaaggt
    57841 ggacgcatca tgcgtttaca ttatgaaggt attttacaag aaagattaga tgaattaggg
    57901 gaaatgccac tgccaccata catcaaagaa cgtttagatg atccagatcg ttatcaaaca
    57961 gtttacgcta aagaaagtgg ttcagcggca gcaccaacag caggattaca ttttactgat
    58021 gagttattaa ctgaaattaa aaataaaggt gttaatatcg catttgttac attacatgtt
    58081 gggttaggta cgtttagacc ggtgagcgtc gatgatgtga atgaccacga aatgcatagt
    58141 gaatattatc aaatgacaca agaaacagct gatttattaa atgatactga gtccaaagga
    58201 catcgcatta tatcagttgg tacaacttca acacgtacac ttgaaacaat tcgacgcgat
    58261 catgataaat ttgttgaaac gagtggctgg actaatatat ttatttatcc aggatttgat
    58321 tttaaagcaa ttgatggcca gattactaat tttcatttac caaaatcaac attagttatg
    58381 ctagtatcag cgtttagtac tcgtgaaaat gttctgaatg cttataaaac ggcagtaaat
    58441 ttagaatata gattctttag ttttggcgat gcaatgttaa ttatataaaa agaatgtgag
    58501 gattttgaat atgcctgcag taacatacga acacattaaa acttgtaaac aatcaggtgc
    58561 gcgtttaggt atcgtgcaca caccacacgg ttcatttgaa acacctatgt ttatgccagt
    58621 tggtactaaa gcaaccgtta aaacaatgag tccagaagag ttaagacaaa ttgaagcaaa
    58681 aatcattttg ggcaacacat atcatttgtg gttacaaccc ggaaatgata ttatcaaaca
    58741 cgctggggga ttacataaat tcatgaattg ggatggtccg attctaacag attcaggcgg
    58801 tttccaagtg tttagtttaa gtaatttacg taaaattaca gaagaaggcg tggaatttag
    58861 acatcatact aatgggtcta aattattttt gagtcctgag aaatcaatgc aaattcaaaa
    58921 tgatttaggt tctgatatta tgatggcatt tgatgaatgt ccaccaatgc ctgctgaata
    58981 tgattatgta aaaaaatcta ttgaacgtac aacacgttgg gcgaaaagat gtctagatgc
    59041 acaccaaaga cctgaagatc aagcattgtt cggcattata caaggtggcg aatatgaaga
    59101 tttaagagaa caaagtgcaa aggatttagt agaattagat tttcctggtt atgcaatcgg
    59161 cggtttgtca gttggtgaac ctaaaccggt tatgtataaa atggttgaac atacagagca
    59221 gtttatgcct aaagataaac caagatattt aatgggtgta ggatctccag atgcgttaat
    59281 cgaatgtagt attcgcggca tggatatgtt tgattgtgtc ttaccgacac gtattgccag
    59341 aaatggtact tgtatgacat cgcaaggtcg tttagttatt aaaaatgcaa aatttgcaga
    59401 tgatttaaga ccgttagatg agaattgtga ctgttataca tgtcaaaact attcaagagc
    59461 gtatatacgt catttaatca aggcagagga aacttttggt attcgtctta ctactattca
    59521 taatttacat tttctgctaa aattaatgga agatataaga caagccattc gagaagatcg
    59581 tcttttagat ttcaaagaag aattcttcga gcaatatgga ttaaatgttg agaacccaaa
    59641 aaacttttaa gcaagaggag cgtataaaat gcaattttca ttactaatat atatagtcgt
    59701 aatttttgcg gttatgtatt tcttgatgat tagaccacaa caaaaacgtg cgaaacagca
    59761 tcgtgagttg attaataaca ttcaatctgg tcaaagaatt acaactattg gtggtattaa
    59821 aggtactgtt aaagcagtag atgaaacaac tgttgttatt acagttaatg gtcatggtac
    59881 tgaattaact ttcgaaaaac ctgctattaa acaagttgac ccttcataac gagaagtggt
    59941 attaaaaagg atgaaacgaa tagcgtttca tcctttttaa gttataagta gtatgtagaa
    60001 tagcttattt ttattccaaa aaaagaaatt gtgatacata ataattgtta aatttaaatt
    60061 aaatatatct atgactattt ttactccctg ctctagtatg ttaatatgta taaggctaat
    60121 aaattttgta agaaagattt aacttgcgtt ataaaatagt attcaagtat tctaaataca
    60181 tacgtaaata atgaggtgtt catgtgaaga aaagtagtag aataattgcg ttcttgcttt
    60241 tagtcgtatt gttgtttgcc ggaatggctg caacttataa aagtgttata aagaatgtca
    60301 atttaggact tgatttgcaa ggtggatttg aggtgcttta tcaagtcgat cctttaaata
    60361 aaggcgacaa aatagataaa aaagccttac aatcaacagc gcaaacatta gaaaatcgtg
    60421 ttaacgtttt aggtgtttcc gaacctaaaa ttcaagttga agaacctaat agaattagag
    60481 ttcaacttgc tggtgtaaca gaccagaatg aagcacgtaa aattttatct tctcaggcta
    60541 atttaacaat tcgcgatgca gaagataaag taaaattaag cggttctgat attaaacagg
    60601 gatctgccaa acaagaattt aaacaggaaa caaaccagcc tacagttact tttaaagtaa
    60661 aagacaaaaa caaatttaaa aaagtaacgg aagaaatctc taagaaacgt gataatgtca
    60721 tggttgtttg gttagatttc aaaaaaggtg acagctataa aaaagaagca caaaagaaaa
    60781 accctaaatt tatttctgca gcaagtgttg atcaaccaat caattctgat agcgtagaaa
    60841 tctctggtgg atttaaagga caagaaggcg ttaaaaaagc aaaacaaatc gccgaattgt
    60901 taaatgcagg ttctttacca gttgacttga aagaaattta ttcaaactca gtaggtgcac
    60961 aatttggtca agatgcatta gataaaactg tgtttgcatc gtttattggt gtagcattaa
    61021 tttatttatt catgcttgga ttctaccgat tacctggttt agtagcgatt attgcattga
    61081 caacttatat ctatctaacg ttagtagcat ttaatttcat ttccggggtt ctaactttac
    61141 caggattagc ggcgttggta ttaggtgtag gtatggctgt agatgccaat attatcatgt
    61201 atgagcgtat taaggatgaa cttcgaatag gtagaacgat aaagcaagcc ttttctaaag
    61261 caaacaaaag ttcgttccta acaatttttg attctaactt aacaacagtt atcgccgcag
    61321 cagtattatt cttcttcggt gaaagttcag ttaaaggttt cgcgacaatg ttattattag
    61381 gtattctaat gatctttgtt acagccgtgt tcttatcaag attcttatta tcattacttg
    61441 tttcatcaaa tatattcaaa aatcaatttt ggttatttgg tgttaaaaag aataaacgac
    61501 atgatattaa tgaaggtgta gatgttcatg accttaaaac ttcattcgag aaatggaatt
    61561 ttgttaaatt agctaagcca ttaattggag taagtatttt aattgtagtt gtcggtttag
    61621 ttattcttta tatcttcaag ttaaacttag gaattgattt ctcaagtggt acacgtgtag
    61681 atttccaatc taaacaagca attactcaac aaaaggttga gcaagttgta aaagatagtg
    61741 gacttaaagc ggatcaaatt caaatcaatg gtaaagataa taaagtagca actgttcaat
    61801 ttaaagacga tttaacgcgt gctcaagata ataaattgag tgataatatt aaatcgaaat
    61861 tcggtgacac acctcaaatt aatactgtat caccaattat tggacaggaa ttagcaaaaa
    61921 atgcaatgct tgcattaatc tatgcatcga taggtatcat catctatgta tcattacgat
    61981 ttgaatggcg catgggtctt tcatctgtat tggcattatt acatgatgta ttcattatag
    62041 tagcgatttt cagtttattt agaattgaag tagatttaac atttatcgcc gctgtattaa
    62101 caattgtcgg ttattcaatt aatgatacaa tcgtaacgtt tgaccgtgta cgtgaaaact
    62161 tacaaaaggt taaagtgatt acgacaacag aacaaattga tgatatcgtt aatagatcaa
    62221 ttagacagac aatgacacgt tcaattaata cagtattaac agttattgta gtagtagttg
    62281 ctatactatt cttcggtgct cctacgatat tcaactttac tttagcatta tttatcggat
    62341 tgatttctgg tgtattctct tcaatcttca ttgccgttcc gctatgggga ataatgaaaa
    62401 aacgtcagct gaaaaaatcg ccgaaacaca aattagttgt atataaagaa aagaaatcga
    62461 acgatgaaaa gattttagtt taaaatgaat taagcggtat gtgaaacaat aaagagttca
    62521 cataccgctt tttactttgt ttaaatttaa caaaatatat ataaataagt tcccgcattc
    62581 atttttaaaa aatggtataa ttaaagtctt gattatttag ataagtgctt tttatttaaa
    62641 gtaattttag atataatgtc ttttggaaat gaggcgtaaa tatatatgat taaaccgaag
    62701 tataagtgga aattaactaa accagctgaa tacataagtg atgaattaac atcaaaatta
    62761 aagttaacgc caatcgtaaa aaaaatatta gaaagtaaat cgattattga tgaacaaaca
    62821 atagaagcca tcatctcaga tacagatatc aatcatgatg cactgcaatt gagcgatatg
    62881 actaagacta ttgaaagaat taaaagagcg atagcgaatg atgagaaaat cctagtttat
    62941 ggtgattacg atgccgacgg tgttacctca actacaattt tagtgacaac attacaactt
    63001 ttaggtgcac aagtaggatg gcatattcct aaccgcttta ccgaaggata tggaccaaac
    63061 gaactagcat ttagaaatgc tcatgatgaa ggcataacat taatcataac tgttgataat
    63121 ggcatacaag gtcataatga aattaaaatg gttcaagatt taggagttga tgtcattgta
    63181 actgatcatc atgaaattgg tagtacatta ccagaagcat atgcaatcgt acatccaatg
    63241 catccatcgt ttaattatcc gttccaacaa ttgtgtggtg caggtgttgc gtacaaatta
    63301 gcacaagcat tgattgaaaa tgtacctgat tattttaaag cattagttgc gataggtacc
    63361 attgcggatt tagtatcctt aactgatgaa aatcgatcat tagtgaaaca aggattaaaa
    63421 gtcttaaatg atcaatgtcc gacctctgtt aaagcgttgc taaaagaagc gggatacaat
    63481 gacaatattg atgaagaaac aattggtttt attattggac ctagacttaa tgctgtaggt
    63541 cgtttagatg acgcatcatt agcttgcgaa ttgttgatga ctgacgacga agaagaagct
    63601 gcatttttag cagaacaagt tgaacatttt aaccgtgaaa gaaaagatat tgtagcaact
    63661 atcacagaag aagcaatggc tatggcagaa acgaaagtta aaaagggaga tttattttta
    63721 cttttagcaa aagaaaattg gcatgaaggt gtcttaggta ttgttgcttc gaaaattgtc
    63781 gaaacatttg ctttgccaac attaatttta aatattgata gggagcaaaa tcatgcaaaa
    63841 ggttccgcca gatcaattga tcaagtgtcg atgtttgaaa tactatcagc acatcaagag
    63901 ttaatcgcta aatttggcgg ccatcatatg gctgcaggta tgacgatgga tattgaaaat
    63961 atagaatcgt tagctgaagg tttaaataaa tggatgaaag aattatctaa aacaacttcg
    64021 ttagatcccg taaagccagt agacgtatta ttaacagaaa atgatataac gattaaaaat
    64081 attcgtgata tgaatcgttt aagacccttc ggaacagatt tttctagacc tatttttgaa
    64141 atggatgatt tgtcagtttc ttcagttaag gcgatcggtc aacaaaaaaa tcatctaaaa
    64201 ttgacacttg gtgaaagtaa tatcgccgcg ctattttggc aaaatggtca cttagaacct
    64261 gagttacaag atgaacagcc aattaatata ttaggatctg ttcaaatcaa cgaatggaat
    64321 ggtaatcaat caccgcaatt aattattcaa gatattgcga tgaatgaaca gcaaatatta
    64381 gattatagaa gtaagcgaaa aagtttacct tttacagaaa atgatgaaaa tattgtcgtg
    64441 cttattcatc ctaaaagtga taaagtaaat gcgaatgaat attattatgg tgaagaaatt
    64501 aaacatcaaa ctgataaagt agtattaaga gatttaccaa cgtcaatgga agacttgtct
    64561 aattccttgc aacaactgca attttctcaa ctttatatag ttttgcaaca taatcattcg
    64621 atttacttcg atggtatacc taatatggat atttttaaaa agtgttataa agcattaata
    64681 actaaacaag aaacaaatat ccagaaagag ggtatgttat tgtgtcaaca tttaagtgtg
    64741 aaaccagata cacttaaatt catgttgaaa gttttcttag atttaaaatt tgtaacacaa
    64801 gaagatggtt taattcgaat caatcaacaa cctgataaaa gatcgattga ttccagcaaa
    64861 gtatatcaat taagacaaca acgtatggat gttgaaaagc aattattata tcaagatttt
    64921 tcagaaataa aaaattggat aaagtcacaa ttgtcgtgag caatttagga ggaaatatta
    64981 atggatttaa agcaatacgt atcagaagtt caagattggc cgaaaccagg tgttagtttc
    65041 aaggatatta ctacaattat ggataatggt gaagcatatg gctatgcaac agataaaatt
    65101 gtagaatacg caaaagacag agatgttgat atcgttgtag gacctgaagc gcgtggcttt
    65161 atcattggct gtcctgtagc ttattcaatg gggattggct ttgcacctgt tagaaaagaa
    65221 gggaaattac ctcgtgaagt cattcgttat gagtatgacc tagaatatgg tacaaatgtt
    65281 ttaacaatgc acaaagatgc aattaaacca ggtcaacgtg tgttaattac agatgattta
    65341 ttagctactg gtggtacgat tgaagcagca ataaaattag ttgaaaaatt aggcggtatc
    65401 gtagtaggta ttgcatttat aattgaattg aaatatttaa atggtattga aaaaattaaa
    65461 gattacgatg ttatgagttt aatctcatac gacgaataat aaataatata attttatcaa
    65521 atgaaatcct tcatcaaatg tataagaacc aatgacttaa ttaaaaaagt tgtttaagtt
    65581 ttcttaacat gagatgttag gattttttat ttactgaaaa tgttagatga ttgagcatta
    65641 taccttaata acatcgttta tttatttcat aaattgtagt atcatagaac taatatttaa
    65701 aaaatgaaac agtagattta ggtcgaattt ttgtaaaagt tttaaaagta ggaatagtat
    65761 acaaattaaa ctcgctcaag taaaattaat attacgatta atgacgacag gataaatatt
    65821 tatcgtcgac ggacgtatga ttggtgtggg acaaatacta ttcaacaaga gtacctaaat
    65881 cattgtttaa ggcgaagtaa taaatatgaa tggggtgtat catataatga acaacgaata
    65941 tccatatagt gcagatgaag ttcttcacaa agcaaaatca tatttgtcag cagatgaata
    66001 tgagtatgtt ttaaaaagct atcatattgc ttatgaagca cataaaggtc agttccgaaa
    66061 aaacggatta ccatacatta tgcatcctat acaagttgca ggtattttaa cagaaatgcg
    66121 attagacgga ccgacgattg tcgcaggttt tttgcatgat gtaattgaag atacaccgta
    66181 tacatttgaa gatgtaaaag aaatgttcaa tgaagaagtt gctcgaattg ttgatggtgt
    66241 gacgaagctt aaaaaagtaa aataccgctc aaaagaagaa caacaagctg aaaatcatcg
    66301 caagttattt attgcgattg ccaaagatgt acgcgtaatt ttggtgaaat tagcagacag
    66361 attacataat atgcgtacct tgaaagccat gccgcgtgaa aaacaaatta gaatttctcg
    66421 agaaacatta gaaatttatg cacctttagc acatcgtctt ggtattaata caattaaatg
    66481 ggaactagaa gatacagctc ttcgttatat tgataatgtg caatatttta gaatagtcaa
    66541 tttaatgaag aagaaacgta gtgaacgtga agcgtatatc gaaacggcta ttgatagaat
    66601 acgtactgaa atggaccgaa tgaatatcga aggcgatata aatggtagac ctaaacatat
    66661 ttacagtatt tatcggaaaa tgatgaagca gaaaaaacaa tttgatcaaa tttttgattt
    66721 gttggcgata cgtgttattg tcaattctat taatgattgt tatgcgatac ttgggttggt
    66781 gcatacgtta tggaaaccga tgccaggacg ttttaaagat tatattgcaa tgcctaaaca
    66841 aaatttgtat cagtcattgc atactacagt agtaggtcca aatggagacc cgctcgaaat
    66901 ccaaatacga acgtttgata tgcacgaaat tgctgagcat ggtgttgcag cacactgggc
    66961 ttacaaagaa ggtaaaaaag taagtgaaaa agatcaaact tatcaaaata agttaaattg
    67021 gttaaaagaa ttagctgaag cggatcatac atcgtctgac gctcaagaat ttatggaaac
    67081 cttaaaatat gacttacaga gtgacaaagt atacgcattt accccagcga gtgatgttat
    67141 tgagttgcca tatggtgctg tgccgattga ttttgcttat gcgattcaca gtgaagtagg
    67201 taataagatg attggtgcca aggtgaatgg caaaattgta ccaattgact atattttaca
    67261 aacaggcgat attgttgaaa tacgtactag taaacattca tatggaccaa gtcgtgattg
    67321 gttgaaaatt gttaaatcgt ctagtgccaa aggtaaaatt aaaagtttct tcaaaaaaca
    67381 agatcgttca tctaatattg aaaaaggccg aatgatggtt gaagctgaaa taaaagagca
    67441 aggatttaga gtcgaagata ttttgacaga gaaaaatatt caggttgtta atgaaaaata
    67501 taactttgca aatgaagatg atttattcgc agctgtagga tttggcggcg tgacatccct
    67561 acagattgtt aataaattaa ctgaaagaca acgtatttta gataaacaac gtgctttaaa
    67621 tgaagcacaa gaagttacga aatcattgcc tattaaagac aacatcatta ctgatagtgg
    67681 tgtctatgta gaaggtttag aaaatgtact tatcaagttg tcaaaatgtt gtaatcctat
    67741 accaggtgat gatattgtag gttatatcac caaaggtcac ggtattaaag tacatcgcac
    67801 tgattgccca aatattaaga acgaaactga acgactaatt aatgttgaat gggtaaaatc
    67861 aaaagacgca actcaaaaat atcaggttga tttagaggta actgcgtatg accgaaatgg
    67921 cttgttgaat gaagtactac aagctgttag ctcgacagcc ggcaatttaa ttaaagtttc
    67981 aggacgttca gatattgata aaaatgcaat aataaatatt agtgtcatgg tgaaaaacgt
    68041 gaatgatgtt tatcgtgtgg tagaaaagat caaacaactt ggtgatgttt atacagtaac
    68101 aagagtttgg aactagaggt gcaaaatatg aaagtagttg tacaaagagt taaagaagca
    68161 tcggtgacga atgatacatt aaataatcaa atcaaaaaag gatattgttt attagtcggt
    68221 atcggtcaga actctacaga gcaagatgca gatgtaattg caaagaaaat tgctaatgca
    68281 agattatttg aagatgacaa taataaatta aactttaata tccaacaaat gaatggtgaa
    68341 atactatcag tttcacaatt tactctctat gcagatgtaa aaaaaggtaa ccgtccaggt
    68401 ttctcaaatt ctaaaaatcc tgatcaagcg gtaaaaattt atgagtattt taatgatgcg
    68461 ctacgagcgt atggtcttac tgtgaaaaca ggtgaatttg gaacacacat gaatgttagc
    68521 ataaataatg atggtccagt cactattatt tatgaaagtc aggacggcaa aattcaatga
    68581 aaaaaataga ggcatggtta tctaaaaagg gtcttaaaaa taaacgtact ctaatagtag
    68641 tgattgcctt tgtcttattt atcatctttt tatttttatt gctgaatagc aatagtgaag
    68701 atagtgggaa catcacgata actgaaaatg ctgaattacg tacaggtcca aacgctgcgt
    68761 atccagtcat atataaagtt gagaaaggtg accattttaa aaagattggt aaagtaggta
    68821 aatggattga agttgaagat acatccagta atgaaaaagg ttggatagct ggatggcaca
    68881 caaatttaga tattgtcgcg gataatacga aggagaaaaa tcctttgcaa ggtaaaacaa
    68941 tagtgcttga tcctggtcat ggaggtagtg accagggtgc ttcaagcaat actaaatata
    69001 aaagtttaga aaaagactat acgttgaaaa cagcaaaaga attgcagcgt actttagaaa
    69061 aagaaggcgc aactgttaag atgacaagaa cagacgatac atatgtttca ctagaaaatc
    69121 gtgatatcaa aggcgatgcc tatttgagta tacataatga tgcattagaa tcatctaatg
    69181 caaatggaat gacagtttat tggtatcatg ataatcaaag agctttagca gatacgttag
    69241 acgctacgat tcagaagaaa ggtctacttt ctaatcgcgg ttcaagacaa gaaaattatc
    69301 aagtgttaag acaaacaaaa gttcctgctg ttttattaga attaggttat attagtaacc
    69361 caactgatga aacgatgatt aaagatcaat tacatagaca aattttagaa caagcaattg
    69421 ttgatggcct taaaatttat ttttctgcgt agggcttgca aaaatatgtg aaagtagtta
    69481 tcattgatat tgaattttat aactaaaacc gttagtattc ttgaaatggt aaatgaaata
    69541 ggtagcaatc taactaagat tgtgtaggaa tataatccat agactgaaag attatgctga
    69601 gtagtttata tacattgaac acaagaagag gtgctttatg aaaagtaaag ccgttaaacg
    69661 tacgttaaac gttttgagtg ggtttattta atgcacgctt ataaaaagta atgatgatta
    69721 caattaggca tgttttttaa accaatgagg gtggcaacac ggatattcgt cccttgtgca
    69781 gtttcaggct gtgcaagggc tttttctttt gcttttaaaa ttatgattta tcatgcaaag
    69841 ttaagtgatc gtatatagtt ttagttttaa aaaggtaatt aaataaaata gtttgccgag
    69901 ggagatgtca aaatgattaa aatacctaga gggacgcagg atattttacc tgaagattca
    69961 aagaaatggc gttacattga aaatcaatta gatgaattaa tgacatttta taattataaa
    70021 gaaataagaa caccaatttt tgaaagtaca gatctttttg caagaggtgt tggtgattca
    70081 accgatgtcg tacaaaaaga aatgtataca tttaaagata aaggcgatag aagtattaca
    70141 ttaagacctg aaggaacagc tgcagttgta cgttcatata ttgaacataa aatgcaaggt
    70201 aatccaaacc aaccaattaa actttattac aatggaccga tgtttagata tgaacgtaag
    70261 caaaaagggc gctatcgtca atttaatcaa tttggtgtag aagctattgg tgctgaaaat
    70321 cctagcgtag atgcagaagt attagctatg gttatgcata tttatcaatc atttggatta
    70381 aaacatttaa agcttgttat taatagtgta ggggatatgg cgtctcgaaa agaatataac
    70441 gaagcgttag tgaaacactt tgaaccagta attcatgaat tttgttcaga ttgtcaatca
    70501 cgtttgcata caaatccgat gcgaattttg gattgtaaag ttgaccgtga taaagaagcg
    70561 attaagactg cacctagaat cactgatttc ttaaatgagg aatctaaggc atattatgaa
    70621 caagtaaaag cttatttaga tgatttaggt attccatata ttgaagatcc taacttagtt
    70681 cgtggattgg attattatac acatacagca tttgaattaa tgatggataa ccctaactat
    70741 gatggtgcca ttacaacgct ttgtggtggt ggccgttata atggtttatt agaattgcta
    70801 gatggtccaa gtgaaacagg tattggtttt gcgctaagta tagaacgatt attgcttgca
    70861 cttgaagaag aaggtatcga attagatatt gaagaaaact tagatttatt cattgttaca
    70921 atgggtgatc aagcagatcg atatgctgtg aagttattaa atcatttgag acataatggt
    70981 attaaagcag ataaagacta cttacagcgt aaaattaaag gacaaatgaa acaagcagac
    71041 cgtttaggtg ccaagtttac aatcgttatt ggtgatcaag aattagaaaa taataaaatc
    71101 gatgttaaaa atatgacaac tggtgaatct gaaacaattg aattagacgc attagtcgaa
    71161 tattttaaga agtagagagg gcgttaaaat atgagtaaga gaacaactta ttgtggatta
    71221 gttactgaag catttttagg acaagaaatt acattaaaag gatgggttaa caatcgtcgt
    71281 gacctaggtg gattgatttt cgttgattta agagatagag aaggaattgt acaagtcgtg
    71341 tttaatcctg cattttcaga agaggcattg aaaattgctg aaacagtacg ttctgaatat
    71401 gttgtagaag ttcaaggtac agttacgaag cgtgaccctg aaacagttaa tcctaaaatt
    71461 aaaactggcc aagttgaagt acaagttaca aatattaaag tgattaataa atctgagaca
    71521 ccaccatttt ctataaatga agaaaatgtt aacgttgatg aaaatattcg attaaaatac
    71581 cgttatttag atttacgtcg tcaagagtta gcgcaaacat ttaaaatgag acatcaaatt
    71641 acacgttcta ttcgtcaata tttggatgat gaaggtttct ttgacatcga aacaccagta
    71701 ctaacgaagt caacacctga gggtgcacgt gactatttag taccatctcg tgttcatgat
    71761 ggtgaatttt atgcattacc acaatcacca caattattta agcaattatt gatgattagt
    71821 ggatttgaca aatactacca aatcgtaaaa tgcttccgtg acgaagattt acgtgcagat
    71881 cgtcaacctg aatttacaca agtcgatatt gaaatgagtt ttgtagacca agaagatgtg
    71941 atgcaaatgg gtgaagaaat gcttaaaaaa gttgttaaag aagttaaagg cgttgaaatt
    72001 aatggcgctt tcccacgcat gacatataaa gaagcgatgc gtcgctatgg ttctgataaa
    72061 ccagatacgc gttttgaaat ggaattaatt gacgtttctc aattaggacg tgatatggac
    72121 tttaaagtat ttaaagatac tgttgaaaat gatggtgaaa ttaaagcaat tgtcgctaaa
    72181 ggtgcggctg aacaatatac tcgtaaagat atggatgctt taacagaatt tgtaaacatc
    72241 tatggtgcta aaggattagc gtgggttaaa gttgtggaag atggtttgac aggtccaatt
    72301 ggacgtttct ttgaaacaga aaatgttgaa acattactta cattaactgg tgctgaagct
    72361 ggtgacttag taatgtttgt tgcagacaaa ccaaatgtcg ttgcacaaag tttaggtgca
    72421 ttacgtgtca aattagctaa agaattaggt ttaatcgatg aaacaaaatt aaacttctta
    72481 tgggtgacag attggccatt attagaatat gatgaagatg cgaaacgtta cgttgcagca
    72541 catcatccat ttacatctcc aaaagaagct gatattgcta agcttggcac tgcgccagaa
    72601 gaagctgagg caaatgctta tgacatagta ttaaatggtt atgaattagg tggcggttca
    72661 atcagaattc atgatggtga gttacaagaa aaaatgttcg aagttcttgg atttactaaa
    72721 gaacaagcac aagaacagtt cggcttctta ctagatgcat ttaaatatgg tgcaccacca
    72781 catggcggta ttgcattagg attagaccga ttagtcatgt tattgactaa tagaacaaac
    72841 ttgagagata caatcgcatt ccctaaaaca gcatctgcta catgtttatt aacgaatgcg
    72901 cctggtgaag tttctgataa acaattagaa gaactttctt tgcgaattcg tcactaaatt
    72961 ttaaaaaatc aataaacttt ggtttgttat aatttcatta attttaatta tgtggtaata
    73021 taacatcata agatagtcat ctgagttgtt cgtaagtttg ctttttaatt tgggcctaac
    73081 actctttgat caagggagcc caatgggttt tcttgcagcg tacacgcctt atatgaagga
    73141 cgtacaaaac aagaaacagg gcacccacct gtatataaca ggccgaatga tcaagctatt
    73201 ataactacgg caatacggac tctatcgata cgcaagactt tgtcttgcgt atttttatgc
    73261 gtttctttaa gtttttaata aagaattagt tgggtttaat agcgtttaat aaatgtttct
    73321 tcgttgaatt tttgaaaaat aatcaaagca ataatgctaa atataaaatt ttaagttact
    73381 atgtacttat gtataaatca gtgaaagagg taaaataatg aaacatcaat tttcaagaaa
    73441 tgaactagcg attggacaac aaggtttaga tttattgaag caacaaactg ttgtcatact
    73501 tggcgttgga ggtgttggtt catttgctgc tgaagcatta gcaagaacga atattggtca
    73561 tattatatta attgataaag atgatgttga tattacaaat gtaaacagac aattacatgc
    73621 tttaactaca acggtaggac aaagtaaagt ttctttgatg gaagaacgta ttaaattaat
    73681 taatccagat tgtaaagtca cacctttaca tatgttttat acagaagaga catatgaaga
    73741 aattttcgat aattacgata tagattattt tgtagatgca agtgatacaa taatgtacaa
    73801 agtacactta atgaaagagt gtcttgaccg agggattaaa gtgatttcca gtatgggtgc
    73861 tgcaaataaa acagatccaa cacgttttac aatttcagat atctctaaaa cacataccga
    73921 tccaatggcc aaaattattc gtcaaaaatt gaaaaaacta ggaattcgta aagggattcc
    73981 agttgtattt tcagatgaaa gtccaattgt cataagagaa gatgtaaaag atatagttgg
    74041 agataaaaat gctatcaatc gaaaaggaca aatgccacct tcttcaaatg cctttgtgcc
    74101 aagtgttgtt ggattaattt gtgcaagtta tgtggtgaat gacgtattaa aagatattcc
    74161 agttcgtcgc attaaagaca aagggcaata attaattttg aaagtcataa ttttcaacgt
    74221 aaggcaagtg taaccgcacc ataaaactaa aactgactag ttcgcaagca tagtagaata
    74281 tgcctcgtgt actagtcagt tttgatttga ttatagctaa aatatcaaag gtaatcgatt
    74341 taatcttatt tttacggcct ttgtttaagt aagttgttat atatttcttt aagttgttgt
    74401 tcacttttag atgtcgtttt tggttcataa taaattttgt ttttaagttt atcaggtaaa
    74461 tattgctgtg aaacatagcc attaacatat tggtgtggat atttgtaacc aatagatcgg
    74521 cctagatctt tagcaccttg ataatgtcca tcttttaaat ggtttggaat ttggcccaca
    74581 tgaccgtttc taatatcgga caatgcacta tcaatggcac tcattgctga atttgactta
    74641 ggtgataagc atagttcgat tactgcttgg cttagtggaa ttctagcttc tggtaaacct
    74701 agacgttctg ctgattcaat agcagcaagt gttctctgac cagcattagg tgaggctaag
    74761 cctatatcct catagctaat tacaagtaat cgtcgaacta ttgtaggtaa atctccagct
    74821 tcaattaatc gtgctaaata atgtaaagcg gcattgacgt cgctaccacg gatagatttt
    74881 tggaaagcgc tcataacatc gtaatgcatg tcaccatcct tatcacttac aaatgcacct
    74941 ttttgtaaac agtctttagc atcttgcaat gtaacatgtc gataaccgtc tttgtcatta
    75001 tctgcgctta atacagctaa ttccaatgca tttaacgcac tacgaacatc accttggctt
    75061 tgtgtagaaa agtaggtcat ggcatcttca tcaattttgg gttgatatgt tttcaaacca
    75121 ttctcatcat cttctattgc acgagttaac gcttggcgca catcttcgtc atttaaagga
    75181 tataactcga aaatttgcgc tcttgaacga atcgctggat tgatagcatg ataaggattt
    75241 gaagttgtag caccgatcaa gacgattttg ccattttcta aatgaggtaa taaaaagtct
    75301 tgtttagctt tatctagtcg atgtatttca tctaataaca agataacttg accagacatt
    75361 ttagcttctt caacaacaag ttgcatatct tttttagtgt tagttacagc attcaattgt
    75421 ctgaatttat attgcgtact gcccgaaatt gctttggcaa tacttgtttt gcctatacca
    75481 ggtggaccat aaaaaatcat tgaagttaat ttttttgtat caaccattct tctgataatg
    75541 cctcttggtc caactaaatg ttgttgggaa atgatttcat ctatattttt tgggcgcatt
    75601 ctcgatgcta atggttctgt actcacattt gtcacacctt tcttatacta tcttaactca
    75661 aaaaatgcta aaatgggaat atcaatattc gaattaagtg aggttataca atgaaaattt
    75721 ctactaaagg gagatatgga cttacattga tgatttctct tgctaaaaaa gaggggcaag
    75781 gatgtatatc attaaagtca attgctgaag aaaataattt gagtgattta tatttagaac
    75841 agcttgtagg tcctttaaga aatgcggggt taattcgaag tgtacgcggt gctaaaggtg
    75901 gataccaatt aagagtgcca gcggaagaaa tctcagcagg ggatattata agactgttgg
    75961 aaggtccaat tacatttgtt gaaagtattg aatcagaacc acctgcgcaa aaacaactat
    76021 ggattcgcat gagagatgca gtgagagatg ttttagataa tacaacattg aaatatttag
    76081 cggaatatgt agatacaagc gaagatttag acggatacat gttttatatt taatcgtata
    76141 aatactatac tataacataa aaacttcata ttataatgtt tagcgaacct ccttagtggt
    76201 atataaatat atacatccaa ggaggtttca ctatggcaga cgaaagtaag ttcgatcaat
    76261 ttaaaggaaa tgttaaagaa acagtaggta acgttactga taacaaagaa ttagaaaaag
    76321 aaggtcagca agataaagcg actggtaaag caaaagaagt tgttgaaaat gctaaaaaca
    76381 aaataactga tgcaattgat aaacttaaaa aataagttca attaaactaa ttaaatataa
    76441 gaggagcgat taatatgagt tttatggata aagctaaaga cgcagtagaa aaatttaaaa
    76501 atagcgataa tgaacaagtt aaaaatgtaa aagataagat aaatgaatat acaggatcga
    76561 ataacgaaga gaaaaaagaa aatgaagata aagagaaata aatttcttta aattttggat
    76621 atgcttttca atattttgaa agcgccccat caaataaaca ctaacacagt gtaaagttga
    76681 aggggcgctt tcatatttgc attagaattt taagtgaatt tgaatcatta ctaaaataaa
    76741 tgattgaaca ataaagacat cttttattca aaatgctgtt actgtttatt tttattaata
    76801 ttatggatac atactttcac ttagtttatt tatcacatta taaagtgttt ttttcattta
    76861 tctgatttat aacattcttg aaccgacgat aagagtctaa ttgcatatct ttatcataaa
    76921 tataacttat tgccataatt tcgttgactt caccataagt ttccataaaa tcttgaattt
    76981 tttgttgaac agtattttct gaacctatta atgatatttt ctgtctttcc atagccatcg
    77041 catattctct cggcgttaat atattttgta gatcatgtgt tggcggttga acgggctgca
    77101 ttctgccacg agtgatacta accataactt gtgccataga tgaagctaaa tattgtgctt
    77161 cttcatcatt ttcagcaacg attgtgttta aacatacaat aacataaggt tcgtctaata
    77221 catcagaagg ttcaaataac gttttgtaaa tttcgatagc ttctttcatt tgttgaggtg
    77281 caaaatgtcc agcgaacaca tatggaagcc ctttacgagc agctaaatgt gcagaatctg
    77341 ttgaagaacc aagaatatat aaaggcacat ttttacctac tgctggataa gcacgaacat
    77401 atgcttgttg gtgagcggga ccgaaatatt gttgtaataa tgaaacttct tccggaaatt
    77461 tataaacacc atcatgttga tctcgtctta atgcacttgc ggtcatcata tctgttccag
    77521 gtgcacgtcc taatcctaaa tcgacacgat ttggaaataa tgttgccatc gtgccaaatt
    77581 gttccgcaac gattaatgga gcatggttag gtaacatgat tcctccagaa cctacacgta
    77641 tgtgtttcgt atgttctaac gtatgttgaa tcaataaagc agtcgctgaa cttactaggt
    77701 tgggagcgtt atggtgttca gcaatccaat atctttcata tgataattcg tctaaatgtt
    77761 gtgcgagctt aaccatatca ttaattgctg ttcgttcatc ttcaccttct cgaattggga
    77821 caaggtttaa tgctgaatat ttaatcgcca tttttgtatc gtccttcctt ttgtatgata
    77881 taagaagtat accaatcgaa taaccagata aatattaaat tgctcataac caaaataata
    77941 gtacgttaca ttttacgaat gaaaaaatat ctgcaaatac taaaatttat aaaaaagaca
    78001 agaataaagc gataaactta aaaaagccta tcgaaaagca tgtgtagaaa atggtaaaat
    78061 ataattaaaa acattataaa taaagttaaa cagaaaagta gaaaaatagt atgtaaggtg
    78121 ctattattgg aacattgata aaattgtgag gagtgtccaa acatggaaat ttatgcagat
    78181 tatgctgcga ccacaccagt aaaacctgaa gtagtagatg cgatgatgac gatttacaat
    78241 tcgcattatg gtaatccatc atcaatacat gctaagggaa gagatgcgcg taaatattta
    78301 gatgagtcaa gacgtcaaat tgcacaatta cttggtgcag atacacatga aattatattt
    78361 acgagtggtg caacagaatc gaataatacg gcaattaaag gcatagtaaa agcaaatgaa
    78421 caattgggta atcacattat cacatcgaag attgaacatc attctgtgtt acatgttttt
    78481 gaacaattag agcgagaagg ttttgatgta acatatctag atgttgatga tacaggtgct
    78541 attgatttag atcaacttga agaaacaatt acagataaga cgattttagt atctattatg
    78601 tttgtaaata atgaagttgg cacagtgcaa caaatttatg atattcaaga tattattgct
    78661 gagacaaatg catatttcca tgttgatgcg gttcaagcaa ttggacatct tgatgttaag
    78721 tttgacgaat ttgagatcga cgcaatgagt attactgctc ataagtttgg cggaccaaaa
    78781 ggtgtcggtg cattattagt taaagaccat gtcacattag attatcctca acttggcggt
    78841 gaacaagaat tgaaacgccg tgcaggtact gaaaatcttg cacaaattgt cgggatggct
    78901 aaagcattac aattagcaga aaagaatcga gacgataaca atattcattt aatgaattta
    78961 aaagaacaat ttttagttaa attacaagaa agagcgattc catttgaatt aaatggttca
    79021 atgacggatg ctacaggcca tattgtaaat ctatattttc cgtttgttga agttgaaacg
    79081 atgttaacat tgttggatat ggcacaaatc tatgtgtcgt ctggatctgc atgtacagca
    79141 ggctctacac aaccgtcgca tgttttagat gcaatgttcg aagatgaaga gcgatcaaat
    79201 cattcgattc gatttagttt taacgaattg actactgaaa atgaaattaa tgcaattgta
    79261 gctgaaattc ataaaatata ttttaaattt aaggaggagt cataattgtc aaataaagat
    79321 atacgtgttg tcgttggtat gtcaggcggt gtagatagtt ctgtaacagc tcacgtctta
    79381 aaagaacaag gttatgatgt cattggcata tttatgaaaa actgggatga cactgacgaa
    79441 aatggcgtat gtactgcaac tgaagattac aacgatgtta ttgaagtgtg taatcaaatt
    79501 ggcattccat attacgctgt taattttgaa aaagaatatt gggataaagt ctttacgtat
    79561 ttcttagatg aatataaaaa aggtcgtact ccaaacccag acgttatgtg taataaagaa
    79621 attaagttta aagccttttt agatcatgcg atgaatttag gtgcagatta tgtagcaaca
    79681 gggcattacg cacgcataca tcgtcatgaa gatggtcatg ttgaaatgtt acgtggtgta
    79741 gataataata aagatcaaac atacttcttg aatcaattat cccaacaaca actttcaaaa
    79801 gtgatgttcc caattggcga catcgaaaag agtgaagtgc gtcgaattgc tgaagaacaa
    79861 ggactagtta ctgctaagaa aaaagattct acaggtattt gttttatcgg cgaaaaaaac
    79921 tttaaaacat ttttatctca atatttacct gcgcaaccgg gtgatatgat aacacttgat
    79981 ggtaagaaaa tgggtaaaca tagtgggttg atgtattaca caataggaca aagacatggt
    80041 ttaggtatag gtggagatgg cgatccttgg tttgttgtcg gtaaaaatct aaaagataat
    80101 gttttatatg tagaacaagg attccatcac gatgcattat acagtgatta cttaattgct
    80161 tcagactatt catttgtaaa tccagaagat aatgacttag atcaaggttt tgaatgtaca
    80221 gctaaattta gatatcgcca aaaagatacg aaagtttttg tgaaacgtga aaacgaccat
    80281 gcactacgtg ttacttttgc tgagccagta agagcaatca cacctggaca agcagttgtt
    80341 ttttatcaag gtgatgtgtg tcttggtgga gcaacaattg acgatgtgtt caaaaatgaa
    80401 ggtcaattaa attatgttgt ataaacaatg gcaacaataa attacttatt tgaagtttca
    80461 gcgttggaaa tgacgaaaga cagtttttga tgagaataat tcatgatgat agagtctggg
    80521 acatcacaat gtcctaggct ctacaatgtt atattggcgg ggccccaaca cagagaaatt
    80581 ggaaccccaa tttcaacagg caatggaagt tggcggggcc ccaacataga gaatttcgta
    80641 aagaaattca accggcaatg gaagttgggg taaacaaatt aattttgtaa aaatatcatt
    80701 tctgtcccac tccctatgca tgagtctaat tatgtattcc tatttttaag tacataatag
    80761 tggtggctaa tgtggaagaa ccattacata ataaaccgtt aatggttctt tagcatttct
    80821 attccattcc cgctttttca tgaatgaaga tgatattaga ttatatttta ttcgttgtta
    80881 agtgattcga gacatacaat ttatcaagat gttataattg atgagaaatg aggttcgtaa
    80941 atgatagatc aacaaacaat ttatcaatac atacaaaatg gaaaaataga agaagcgtta
    81001 caagcattgt tcggaaatat cgaagaagat cctacaatta ttgaaaatta tattaatgcc
    81061 ggtatcgtac ttgctgatgc gaatgagatt gaaaaggcag agcgcttttt ccaaaaagct
    81121 ttaacaatag atccgaagaa tggcgtagta ttttataatc tagcaaatgt atattataat
    81181 cagcagcgtt atcaagaagc tattaaatta tatcaacaag cattacaaac agagattgaa
    81241 caagttgatt gtaattatat gatcggtatg gcgtttaatc agttagaatc atttaagctg
    81301 gcattgccgt atttaatgac tgctgcggaa ctagataaag acaaagatgc agaagttcaa
    81361 tttcaatatg gtcttgtatt atgtcaatta gaaatgttta atgaagccat aactcaactt
    81421 aaacatgtat taacgattga taaaaatcat gttgatgcaa gatacaattt gggcttagcg
    81481 ttatttatga aaaatgaaga tattgatgaa gccataactc attttaaaga agctgtgact
    81541 atcgacccta aacacttatt aagtcagcat gcgctgaaaa cattcactaa aatgaaagag
    81601 gaggaatagc atgtcagacc ctacactatt tgattattca atgatcaaag gtactgttga
    81661 agcgatattg tttcaaaaca gtgataattt ttatacagtg cttaaagtag atactattga
    81721 aacaaatgaa gactttgata caatgccaac tgttgtaggg tttcttccga atattgttga
    81781 aggcgatgtc tacacattta aagggcaagt tgttgatcat ccacgttatg gtaaacaatt
    81841 aaaagcagag acttttgaaa aagaaatgcc acaaacgaaa gaagcaatta taagttattt
    81901 atcaagtgat ttgtttaaag gtgtaggtaa aaagacagct caaaatattg ttaatgcatt
    81961 aggtgacaat gcgataaatg atatcttaga tgaccattca gtgctagaaa aagtatcggg
    82021 attatctaaa aagaaacaga aacaaattgc agaacaaatt tcagcaaacc aagaatctga
    82081 aaaaataatg attcgtttac atgatttagg gtttggccct aaactttcaa tggcaattta
    82141 tcagttttat ctcggtgata cactgactat tttagaccaa aatccatatc aattgattta
    82201 tgatattaaa ggtattggtt ttaataaagc agatcaactt gctagaaata ttggtatcgc
    82261 ttataacgat aatgaacgat taaaagctgc gttgctctat acgttagaag aagaatgtat
    82321 taaacaggga catacatatt tgcctatcaa tgttgttata gatttaacgg ttgatgtatt
    82381 aaattatcaa gatgaagagg tcatcgaacc tgaaaaatta gacgaaatgt tgcaatactt
    82441 aaatgaggaa aaacgactaa ttattgacaa tgaacaagtt gcaattccaa gtttgtatta
    82501 ttctgaaatc aaaagtgttc aaaacttatt cagaataaag acgcatacaa ataaacttac
    82561 agaaattgaa cagtcagatt tacaaatgca tattggtgaa atagaagatg cgaatcaagt
    82621 gaactatgca gcttcacaaa aagaagcttt gcaaacggct atcaattcta aggtgatgct
    82681 attaaccggt ggaccgggaa ctggaaaaac gacagtaatt aaaggcattg tagaattata
    82741 tgctgagatt catggcttat cattagatta tgatgattat gtcaatgatg attatccagt
    82801 tgtattagca gcgccaacag gaagagcgtc caagagacta caagagtcaa ctggattaga
    82861 agctatgacg attcatcgtt taataggttg gaatcaagac acaaagccag aggatatatt
    82921 agaaaatgaa ataaacgcac gactcataat cattgatgag atgtctatgg tagatacttg
    82981 gttgtttcac caatttttaa gtgcagttcc tttagatgca caattgatat ttgtaggtga
    83041 tgaggaccaa ttgccttctg taggtcctgg tcaagtattt aaagatttaa ttgaatcgaa
    83101 agctatacca cgagttaatc tgactgaagt atatcgtcaa caagatggtt caagcattat
    83161 agaattagca catcgaatga aattgggtca gaaaattgat attacacagc gttttcatga
    83221 tagaagtttt attaactgtc aggcaaacca aataccaaca gttgttgaga aggtagttac
    83281 tagtgctgtt aataaagggt atactatggc tgatattcaa gtgcttgcac caatgtataa
    83341 aggaaatgcc ggtattaaac gtttaaatca agttttacaa gatattttaa accctaaaaa
    83401 gaaagacaca cgagaaattg agtttggtga tgtagtcttt agaaaaggtg acaaagtatt
    83461 acaacttgtt aataggccaa atgataacat attcaatggt gacataggag ttattgttgg
    83521 tattttttgg gcgaaagaaa atgcccttaa taaagatgta cttgttgtgg atttcgaagg
    83581 taatgaaatt acatttacga aacaagatat gatggaatta acgcatgctt attgtacatc
    83641 aatccataaa tcacaaggtt cagaatttcc tattgttatc atgcctattg ttaaacagta
    83701 ttttagaatg ttacaaagac cgatattata tactggttta actagagcga aaacgagttt
    83761 agttttactt ggtgatccag aagcatttga tattggattg aaaacaaatg gtcaagcgcg
    83821 tttaacacaa ttatgtacat tgttgaaaaa ttattttaat tcagaagatg aagaaatgct
    83881 agaaaacaca gcaactaatg atacaggagc ttcacaaacg acaatagatg atcaagtaga
    83941 agcgccaatg ccatcgaatg atagtgaaga agttacgtct gattcaacaa aaacagatac
    84001 aaatgtatta acggaagcta caatgtttaa aattgaccca atgattaata tgggagaaat
    84061 cacgccgtat gactttatag aacgttgaca acaagcgtaa atgtaactaa aatagaatta
    84121 aattcgtata aagatgagta gttaatgatt tgtttatcag agatgtactg gttggtgaaa
    84181 agtacaacaa acattagtga acgctacttt atgcacaact gtatagtcga tttaaagtga
    84241 taaatgtgtt gaattgcatt tataactagg gtggtaccgc gataacgttc gtcccttttg
    84301 aggatgggcg ttttttattt tttaataata aaaaatgata ttgatttata ctagtttttc
    84361 aaatcgacta tctgtgtcat caatttttat ggaatggtaa tttaaaaaca gtaaatagga
    84421 tgtgtaaatg atgaaaaagt taaaagcgag tgaaattaga caaaaatatc tagatttctt
    84481 tgttgaaaaa ggacatatgg ttgaaccttc tgcaccatta gtgccaattg atgatgatac
    84541 attattatgg attaattcag gtgtagcaac attaaagaaa tattttgatg gacgtgaaac
    84601 acctaaaaag ccaagaattg taaactctca aaaagctatt cgtacaaatg atattgaaaa
    84661 tgttggtttc acagcgcgtc accatacatt ctttgaaatg ttaggtaact tctcaattgg
    84721 tgattatttt aaacaagaag cgattgaatt tgcttgggaa tttttaacga gtgataaatg
    84781 gatgggaatg gagccagata aattgtacgt tacgattcat ccggaagata tggaagcata
    84841 caacatttgg cataaagata ttgggcttga agaaagtcgt attattcgca ttgaaggtaa
    84901 cttctgggat attggtgaag ggccttcagg accgaacact gagattttct atgatcgcgg
    84961 agaagcatat ggacaagacg atccggcaga agaaatgtat ccaggtggag aaaatgaacg
    85021 ctatcttgaa gtatggaact tagtatttag tgaattcaat cataataaag atcatagtta
    85081 cacaccatta cctaataaaa acattgatac tggcatgggg cttgagcgta tggcctcagt
    85141 ttctcaaaat gtacgtacta actatgaaac agatttattt atgcctataa tgaatgaaat
    85201 cgaaaaagta tcaggtaaac aatatttagt aaacagcgaa caggatgtgg catttaaagt
    85261 aattgctgac cacattcgta cgattgcatt tgcaatttct gatggtgcat tacctgccaa
    85321 tgaaggtaga ggatatgtat tacgtcgatt gttacgtcgt gccgttcgtt ttagtcaaac
    85381 gttaggaatc aatgagccat ttatgtacaa acttgttgat attgttgcag acattatgga
    85441 accatattat ccaaatgtta aggaaaaagc agatttcatt aagcgtgtta taaagtctga
    85501 agaagaacga ttccatgaaa cattagaaga tggcttagcg attttaaatg aattaattaa
    85561 aaaagctaaa gcgacaacaa atgaaattaa tgggaaagat gcatttaaat tgtatgatac
    85621 gtacgggttc ccaattgaat taactgaaga aatagcagtg caagcaggat tgaaagttga
    85681 tatgacaaca ttcgagtcag aaatgcaaca acaacgtgat cgtgcacgtc aagcacgtca
    85741 aaattctcaa tcaatgcaag ttcaaagtga agtattgaaa aatattacat ctgcaagtac
    85801 ttttgttggt tatgatactg cgacagctca aacaacacta acacacttga tatacaatgg
    85861 cgaagaagtt tcacaagttg aagcgggtga aacagtatac ttcatgttaa cggaaacacc
    85921 attttatgca gtcagtggtg gacaagttgc ggatacaggt attgtttata atggcaattt
    85981 tgaaattgct gttagtgaag taaccaaagc accaaatggt caaaacttgc ataaaggagt
    86041 agtacaattt ggccaagtaa atgttggcgc tacagtgtct gctgaagtga accaaaatga
    86101 tcgacgtgac attcaaaaga accatagtgc aacacattta ttacatgcag cgttgaaatc
    86161 agtactgggt gatcatgtta accaagctgg ttcactagta gaagcagatc gtttacgttt
    86221 tgatttctct cattttggtc caatgactaa ggatgaaatt gatcaagttg aacgcttagt
    86281 aaatgaagaa atttggaaag gtattgacgt taacattcaa gaaatggata ttgcttcagc
    86341 taaagaaatg ggcgcaatgg cattattcgg tgaaaaatat ggtgatgttg tgcgtgtagt
    86401 aaatatggca ccattttcaa ttgaattatg tggtggtatt catgtccgca atacttctga
    86461 aattggctta ttcaaaatag taagtgagtc aggtacagga gctggtgtgc gtcgtattga
    86521 agcattaaca ggtaaagcag ctttcttata tttagaagat attcaagaga aatttaatac
    86581 gatgaaatca cagctgaaag tgaaatctga tgatcaagta gtcgataagt taacacaatt
    86641 acaagatgaa gaaaaagcat tattaaaaca attagagcaa cgtgacaaag aaattacatc
    86701 acttaaaatg ggtaatattg aagatcaagt tgaagaaatc aatggctata aagtattggt
    86761 tactgaagtg gatgtaccaa atgcgaaagc aattcgctcg acaatggacg attttaaatc
    86821 taaactacaa gatacaatta tcattcttgc aagtaatgtt gatgataaag tatcgatggt
    86881 tgcaactgtc cctaaatctt taacaaataa cgttaaagcc ggtgatctta tcaaacaaat
    86941 ggcaccaatc gttggtggta aaggtggcgg tcgtccagat atggctcaag gtggcggtac
    87001 acaacctgaa aatatctcaa aatcattaag ctttattaaa gattacatta aaaatctata
    87061 atttatagcc ataatattgt atgatgatag tgagttatat ttgtaattaa aggagtgtcg
    87121 caaatggaaa actttgataa aacaatgaaa ttcgactatg aagaacttcc aacacaagat
    87181 gtaagagatg ttttaaataa tgtttatcga acattagatg aacgaggata taatgccgta
    87241 aaccaaattg taggttattt attatcaggt gaccctgcgt atattccacg ccaaaatgaa
    87301 gcaagaaatc aaattcgtca tattgataga gatgttatta tggaagagct tgtttcttac
    87361 tatttaaaag agcaaaataa ataatttatg ttacaacata aaattttagg actcgatgtc
    87421 ggtagtagaa cggtaggaat tgcaattagt gatataatgg gttggacggc acaaggatta
    87481 gacacactcc gaatcaatga agaaaataat gaattaggta ttgaccaatt agtagacatt
    87541 attaaaaaac ataatgtggg tacagtcgta ataggactac ctaaaaacat gaataattca
    87601 ataggatttc gaggcgaagc ttcgttaaca tataaagaaa aattattaga agcttatcct
    87661 tctattgaga ttgtgatgtg ggatgaaaga ttaagcacaa tggctgctga acgatcatta
    87721 ttagaagcag atgtttcaag acaaaaaaga aaacaagtga ttgataaaat ggcagcggta
    87781 tttattttac aaggctattt agattcacta cattaaaagg agattttact atgactgaac
    87841 ataatcatga ttcacaacta gaaattaata acgaagaaga attattaact ttattcgatg
    87901 aagagggaaa tgaagtttta taccgaaaag ttttagaatt ttatcatcct gaattcaaaa
    87961 aagagtatgt tatcttagct gaagaaggtg ctcaatcaga tgaagacgat atgattgagc
    88021 ttgtaccaat gatcaatgaa ccagatgagt caggtgacgg tggtaagtta gtaccaatcg
    88081 aaactgatga agaatgggac atgattgaag aagttgtaaa tactgaaatg gaagaataat
    88141 taaaaagatt ttactcttgc taaccttaag atggggaggc aagagtattt ttttaagtca
    88201 agcaatgtat aaataattaa cgcttataat tttattgaaa atatggtaaa atatctaaag
    88261 ttaaatttta tatgaatgat tcgcttctat aaataaaata gctttgcgtc taacacgaaa
    88321 tcagtcattt aattggttgg caaaatcata atcaattgtg aaggctgatt tattttattg
    88381 tcataatcat attgacttat tttacataaa ggaagtttaa aacatggatg acctaaataa
    88441 aaaatattta atagatttac atcaacatca aaatagttca atcgaagttt tgcgtgaatt
    88501 tgccgaagta aatgaagtgc caatcgtaga tcgtttaaca ttagatttaa ttaagcaatt
    88561 aattcgtatg aataatgtta aaaatatttt agaaattggt acagcaatcg gctatagttc
    88621 tatgcaattc gcttctatat ctgatgacat tcatgtcaca acgatagagc gtaatgaaac
    88681 gatgattcaa tatgctaaac aaaatttagc tacttatcat tttgaaaacc aggttcgaat
    88741 tattgaaggt aatgctttag agcaatttga aaatgtaaat gacaaagttt atgatatgat
    88801 atttattgat gcagcaaaag cgcaatcaaa gaaatttttt gaaatatata caccactttt
    88861 aaagcaccaa ggtctcgtaa ttacagataa tgttttatat cacggttttg tatcggatat
    88921 tgggattgtt agatcgagaa atgtaagaca aatggttaaa aaggttcaag attataatga
    88981 gtggttaata aagcaaccag gatatacaac gaatttttta aatatagacg atggattagc
    89041 gatttcaatt aaaggagaat gactatgaca gaattacttg tcacacccaa gtcattaagc
    89101 catatggaaa cacttattga tttaggtgca gatgcttttg taattggcga gcaaaagttt
    89161 ggtttaagac ttccagggga attcaataga caacaaatga cagaggctgt cgcattagct
    89221 cacaaaaacg ataaaaaagt atatgcggcg gtgaatggat tatttcataa ttatcattta
    89281 gatgctgtag aagattatat taatttttta catgaaatac gagttgacag aattattttc
    89341 ggggatccag cagtagtaat gtatgtgaag gcgcaagaga atccaatacc acttcattgg
    89401 aatgcagaga cgttagtaac taatcatttt caatgtaatt actgggggaa aagaggcgca
    89461 tcaagagctg tcttagcacg tgagctgaat ttggatgaaa ttattaatat aaaagaaaat
    89521 tcaaatgtgg aaattgaggt gcaagttcaa ggaatgactt gtatgttcca atcaaagcgt
    89581 atgctactag gcaattatta tacgttccaa gatcgccaaa tgaaaattga acgtcgcaat
    89641 gatgaacaat ctttattact ttatgatgaa gaaagacaaa ataattaccc agtttacgaa
    89701 gattacaatg gtacgcacat tatgtcacca aacgacattt gtttaattga agaattagca
    89761 ccattttttg aggcgggtat agattcattt aaaatcgatg gtattctaca aacggaagaa
    89821 tatattaatg tggtaacgga acagtatcgt caagcgatag atttgtacaa tgaagatcct
    89881 gaaatctatg aagatgagaa atttatgttg atggacccaa ttgaagaaat tcaacctgat
    89941 catcgaccat ttgacgaagg tttcttatat aaacaaacgg tatattaagg aggttaatca
    90001 tgaagacaat agaagagatt aaatcaactc ctaaaacagt tatgaagaaa ccagaattat
    90061 tagcacctgc tggaaactta gaaaagttaa aaatagcagt acattatggc gctgatgccg
    90121 tatttttagg tggtcaagaa tatggattac gttcaaatgc tgataatttc acgatggaag
    90181 aaatagctga aggtgttgaa tttgcgaacc gttacggtgc caaaatttat gttacgacaa
    90241 atattattgc acatgatgag aatattgaag gtctagaatc atatttgcgt aatttggaaa
    90301 agactggtgc gacaggtatc attgttgcag atcctttaat tatcgaaaca tgtaaagaag
    90361 ttgcgccaaa acttgaaatt catttatcta ctcaacaatc actttctaat tacaaagctg
    90421 tagaatattg gaaagaagaa ggattggatc gtgttgtatt agcacgtgag accggcgcga
    90481 tggaaatgcg tgaaatgaag gaaaaagtag atattgaaat cgaagcattt attcatggtg
    90541 ctatgtgtat cgcctattca ggtagatgta cattaagtaa tcatatgact gcaagggatt
    90601 ccaacagagg cggttgctgt caaagttgcc gttgggatta tgaattatta gaagttgatg
    90661 ataatggtga acttgatgta ttttataatc aaggtgaagt tacaccgttt gcgatgagtc
    90721 ctaaagattt aaaattaatc gaatcaattc ctcaaatgat ggatattggt gtggactcat
    90781 taaaaattga aggacgtatg aagtcaattc attatattgc aacagttgtc tcagtatatc
    90841 gtaaagtcat tgatgcgtat gcggcagatc ctgacaactt taagattaat ccggaatggt
    90901 taattgagtt agataaatgt gcaaatagag acactgcacc agcattcttt gagggtacac
    90961 ctggttatga agaacagatg tttggtcaac aacaatctaa aaaatcacca tttgattttt
    91021 gtggtttggt attagattat aatgaagata caaaaattgc gactattcaa caacgaaata
    91081 actttaaacc aggtcaagaa atagaattct ttggtccaga aattgaaaca tttacacaag
    91141 tagtagaagc aatttatgat gaagaaggta acagcttaga cgcggcgcgc catccattac
    91201 aaatcgttca aattaaagtg gatcgcccga tatatccaaa caacatgatg agaaaggaaa
    91261 ttggctaatg aaagctacta caatcattgg catagctggt ggatctggct caggaaaaac
    91321 aactgtaact aacgaaatta tgaaaaactt agaaggtcat agtgtcgctt tacttgctca
    91381 agattactat tataaagatc aaaagcactt gactttcgac gagcgcctag aaaccaatta
    91441 tgaccatcca tttgcatttg ataatgattt attaattgaa aatcttaaag acttgaaaaa
    91501 tggtaaagca gtagaagtac cgacatatga ttatgctagt catacaagaa gtgatattac
    91561 cattgatttt aaacctaaag atgttattat cgtagaaggt attttcgctt tagaaaataa
    91621 ggtattacgt gatatgatgg atgttaaaat atatgttgat acagatgcag acttaagaat
    91681 attacgccgt ttaacacgag atactaaaga gcgtgggcgt tcaatggact ctgttatcaa
    91741 tcaatattta agtgttgtta gacctatgca tgaccaattt attgaaccga ctaagaaata
    91801 tgctgatata attatacctg aaggtgggag caataaagtt gcaatagata ttatgacaac
    91861 aaaaattcag tctttagtta gcaagcaata gtataattca gtaaaggaag atgacaatat
    91921 ggaaaatcaa aagcaatatc caatgactca agaaggtttt gaaaaattag agcgtgaact
    91981 tgaagaatta aaaacagtta agcgtcctga agttgtagag aaaattaaag ttgcacgttc
    92041 atttggtgac ttatcagaga actctgagta tgatgcagca aaagatgaac aaggattcat
    92101 cgaacaagat attcaaagaa ttgagcatat gttaagaaat gcattaatca ttgaagatac
    92161 tggagataac aacgttgtta aaattggtaa aacagtaacg tttgtagaat taccaggtga
    92221 tgaagaggaa agttatcaaa tcgttggttc agctgaatca gatgcattta atggtaagat
    92281 ttcaaatgaa tcaccaatgg ctaaagcgtt aattggtaaa ggtttagatg atgaagttcg
    92341 tgttccacta cctaatggtg gcgaaatgaa cgtaaaaatt gttaatatcc aataaatgat
    92401 caaatagatt gtttaattgc gcgattgaag tgtgttaatg atacttcggt cgtgcttttt
    92461 tatattcaaa atcaaaaaat cggacagatg aaaagtaaaa attttccatc agaccgattg
    92521 atagcagaac ctaaattagt gtaagagttt caatattaac tactccattt taaaaaaagc
    92581 aaaatatttc caagaaaaca aattgattat aatttgttat tgtatgcgat ttgaattact
    92641 tattaaacaa cttgtgcttc tcaatgatac aatgaaaagg tattcaatac tggtttattg
    92701 caatacaaag ggggatttag agtggatgta agatttatta acgagcagac aattatgatt
    92761 tattttgaaa ataatatatc cgaagagaca tatcgaaatg tcacagcaat ggtacggtgg
    92821 atacgagaaa aagaaatatt agaaattcaa gacattgtcc cttcgtatcg agcagttcta
    92881 atatattttg atgaacaagc tataacatct tctaaattaa ttgaaaattt agaacttaac
    92941 aaatttaatg aaaaaaatgt tcatgctgtg aatcaaacca atcgaattat taaaatacct
    93001 gttcaatatg gtggtacata tggacctgat attgaggaag tagcaaagca taatcgaata
    93061 actgttgagc aagttattga aaaacataca agtaaacctt atttaatata tatgctagga
    93121 tttatgcctg gatttccata cttaggcgga cttgatcaac aactacatac acctagacgt
    93181 aatcagccaa ggttaaaaat tcatgcaggt tctgtaggta ttgcgaataa tcaaacagga
    93241 ctatatccat cagattctcc tggcggatgg caaattattg gacgcacacc gttaaaagta
    93301 tttagcagcg agcgtgaacc aatgtcaatg tacgaagcag gagaatggat acaattttat
    93361 gcaatagatg aacaggaatt tatacaaatc gaaagagata tatcagatgg caactttaat
    93421 gttgatgact gggtggtgat tgaaaatgtc aattaagatt ttacaaccag gtctcttttc
    93481 aacggtacaa gatctaggaa gaaaaggtta tgaacatatt ggattttcag gctcaggtgc
    93541 catggatcaa tttagtttta aggttgcgca gtcattaatt aacaatgatg gtccagcgat
    93601 tgaatatact ttgattggtc ctaccattca atttaatacg caaaatacat ttgttataac
    93661 cggtggtagt gttaatgcct cgctaaataa taaaactata tcaatgaatt ctgtcatatt
    93721 agctgagaaa ggtgacattt taaaaatagg tgctataacc aaaggtgcac gcggttatct
    93781 tacttttggt cattctatca acgtaccttc tattgctgaa agttatgcaa cacatacccg
    93841 aagcagtata ggaggattca aaggtagaaa gttattagct aatgacgtaa taacagtgaa
    93901 aataaataat gactttaaag aaaacattgg aaagactatt catttacagg acgatttatt
    93961 accagaaaat aatattatac acattcttca aggacctcaa ttcgaggcat tttctgaaga
    94021 ggctagagcg aaaattgtaa attatccata tttaataact gaacaatcag accgtatggg
    94081 gtatcgtttg gaaggtgaca gcgttgcacc aattaatcaa gcagatatca tttctgaacc
    94141 ggttgctctt ggcagtgttc aagtaccaaa tgatggtcaa cctattattc tgcttaatga
    94201 taaacaaacg ataggtggtt ataccaaaat tgcaactgta tgcaaatttg atctgccaaa
    94261 gttagcacag atgaaaccac aagatacaat tcaatttaaa tggatatcat tccaagaagc
    94321 tgtagataag aatcgggaac aaatgtctct gtttaatgaa attcttaaga gtcatcaaaa
    94381 gactccaatt tttgatacat ctagcttgcg acatacttcg aaaaaattag caacaatttt
    94441 aaaaggggat ttgtaaaatg aatattgaaa aaatcgaaca aataatcaaa ttagtgaagg
    94501 aaaatgatgt taagaaattt aaatataaaa attttgaaga tgaaatagaa attaacttca
    94561 ctgactcgaa tcatttggct gcacacagta atcaatcaaa tcaaagtatg aacaataatg
    94621 atttgacagc ttcaaaagcg aatgataact ccgatgtttc gacaaatgat tatcatgaca
    94681 ttaaatcacc aatggtaggt acattctttt tacaagatag taaagaatta actgaaccaa
    94741 ttgtgaaagt cggtgacaaa gttaacaagg gagatattat aggatatgtt gaagcgatga
    94801 aagtattaaa cgaggtaaca acagatgttg ctggagaaat tactgaaata gtagctgatc
    94861 acggcacaaa tgttgaatac gaccaagttt tggtacgtat taagtaaagg gggtaagtaa
    94921 atgcttcgtt gtttaattgc gaacagaggt gaaattgctg taaggattat aagagcttgc
    94981 agagaatatg ggattgaaac tgtagcagtt tatgcaaaac gggacgagca aagcttgcat
    95041 gtacatttag cagatcaagc tatatgtatt ggggaagcta atgctttaga tagttattta
    95101 aatattgacc gcatcatatc tgctgcacaa atcactggtg ctaatgcaat tcacccagga
    95161 tatggatttt tatcagaatc aacaaaattt gctcaaaccg ttgaggaaca aggcatagcg
    95221 tttatagggc ctactaaaaa aacgatggaa atgatggggg ataaaataac agcaagacaa
    95281 acagttcatc atgcaggtgt tcctgtgatt ccaggatcaa atggtgctgt gaatcatgtg
    95341 tctgaaattg agaagcttgc caaagacatc ggttatccag ttgttatcaa agctgccagt
    95401 ggcggtggtg gtaaaggtat acgtattgta aagaaagctg aagatttaga aaaggcattt
    95461 aaagaagcta aaagtgaagg aaaaaaatac tttgatgatg atcgtgttta tgttgaggct
    95521 tttatacctg ttgcaaaaca tgttgaagtt caagttatgg gggatgggca ggataattat
    95581 gtacatttag gggaacgtga ttgttctgta caacgtaaaa atcaaaaatt aatcgaagaa
    95641 tctccttgtg cagcattaac tgaagaaagg cgacaacaaa tatgtaatga tgctgttaaa
    95701 gttgcacgtg cagcaaatta tagaagtgca ggtacgattg aatttttagt aactgatacc
    95761 gcacattact ttattgaaat gaatgctcga attcaagttg aacatactgt tacagagatg
    95821 cgagcagaac gtgatttggt tgcagcacaa ctgtatttat tggaacataa tcatttacct
    95881 ttctcacaaa gcgatattca atttaatggt catgtgatag aagcgagaat aaatgccgaa
    95941 aatcctgaaa agaaatttca accaacacca ggtaaagtga cagcgttaca tttacctcaa
    96001 ggctttaatg tgcgagtcga ttctttacta tatcacggtt atcaagtttc accatattat
    96061 gattctttag tagctaaagt aattgtaaaa tctcatgata gagcttcagc aattgataag
    96121 ttgaaagcca ccttagatga aatggtgata gatggatttt ctacaactgc cgatttttta
    96181 tatgcagttt taaattatcc actatatcgt gatggagatg caaaagatgt tgatattaaa
    96241 tttttagaaa aacatcaaat tgttaaaggg gtggaattat aatgcgagtt gatttgaatt
    96301 gtgatttagg cgaagcattt ggaaattatt cctttggtgg tgatcatcaa attattccgt
    96361 taattacaag tgcgaatgtt gcttgtggtt ttcacgctgg tgatgaaaat gtaatgaatg
    96421 aaacggtaaa acttgccaaa gcacataatg ttgcagtagg tgcacatcct ggtttacctg
    96481 atttgaaagg ctttggcaga cgaaatatag atatctctaa cgacgagatt tataatttga
    96541 tgatttatca attaggtgca ttacaagggt tttgtcgcat tcatcaagtt aaaattaatc
    96601 atgttaaacc gcatggtgca ttgtatcaga tgggtgcaaa agacagagaa atagcaagcg
    96661 ttatagcaca agctgtttat gactttgatc catcactagt gttagtagga ttagcaaatt
    96721 catatctaat ttcagaagca aagaatgtcg gattaattac agcttctgaa gtgtttgctg
    96781 atagacgata cgaagatgat gggcagctcg ttagtagaaa agaaagtgat gctgtgatta
    96841 ctgatactga cgaagcactt aagcaggttt taaagatggt gaaggaaaat aaagttattt
    96901 caaaaaacaa taaggaagta acgttacaag cagatacaat ttgtgtgcat ggtgatggag
    96961 aacatgcatt attatttgtt tcgaaaatta gagaaatttt aatgaaagaa ggcattgata
    97021 ttcaatcctt atagggggct aaaaaatggg gagaaattta aagcttaaac atcgtgaaag
    97081 tgattttgaa tttactaaaa accataagag attattgtta ggttctgtat ttctgatggc
    97141 aacttctgca attgggccag catttttaac gcaaacagca gtatttacat cacaattttt
    97201 ggcgagtttt gcattcgcaa ttttactatc aatcattatt gatattggtg cacaaattaa
    97261 tatatggcgc atattggttg tcactggttt aagaggtcaa gaaatatcaa ataaagttgt
    97321 tcctgggctt ggtactgtta tctcaatatt gattgcattt ggaggtctag cttttaatat
    97381 tggtaatatt gctggtgccg gtttaggttt aaatgcaatt tttggattag atgtaaaatg
    97441 gggcgcagct attactgcaa tctttgcaat attaatcttt gtaagtaaaa gtggccaaaa
    97501 aattatggac gttgtttcaa tgattcttgg tattgtgatg attttagttg tggcatatgt
    97561 gatgtttgtt tctaatccac cttatggtga tgcttttgtg catacatttg cgccagaaca
    97621 tccaatgaaa ttagtcttgc caatcattac gttagttggt ggaactgtag gtggttatat
    97681 tacctttgca ggtgcacatc gtattttaga ctctggcatt aaaggtaagc aatatttacc
    97741 atttgtaaat caatcagcaa ttgctggtat tttaactaca ggtattatga gaacgttact
    97801 attcctagcg gtattaggag ttgttgtaac aggtgtgaca ctaagttctg aaaatccacc
    97861 agcgtcagtt tttgaacacg caattggacc aattggaaag aatatttttg gtattgtgtt
    97921 atttgctgca gctatgtcat cagtaattgg ctcagcatac acaagcgcaa catttttaaa
    97981 aacacttcat aaatcacttg acgaaagaag taatttaatt gtcattgtgt ttatcgttat
    98041 ttcaacaatg attttcttgt ttattggaaa accaatcagc cttttaatta tagcaggcgc
    98101 gataaatgga tggattttac ctattacgtt aggtgcaatt ttgattgcaa gtaaaaagaa
    98161 atcaattgtt ggtgattata aacacccaaa ttggatgttc atctttggta tcgttgcagt
    98221 acttgttaca atattgacag gtatattctc attcaaagaa gtacttcagt tattttaaaa
    98281 gacatttcga ataatagtat cactgtaaat gttgttagta ttaggcaaga tgtattttga
    98341 tttccggtga ttcatttata aagcataatt gaatatattt taagaaagag agtggtgcat
    98401 gataaatgta ctgctctttt ttgttatgat gaaaaatctt tttctattga tcgagaaaat
    98461 agttatttat atagttttta aagaaaaaaa gtgataatat ttagctaatc taatgaaaat
    98521 ggatttattg gacaaaaaat acattttaaa tgagtagagg aggctgcaaa tgggttacag
    98581 aactttaaaa agtatttttc atgagcataa cgaaagtaaa atgaaagacg agtatactaa
    98641 aagatttaat tctttagcat ctttcaatac taatattaat atcataccca tggaaaatgg
    98701 aaaaaaagtt aatgatttgg aatatcctct attctttatg gtgactaaaa atctatcaaa
    98761 aaaacaagaa ttaatatcaa ttaatagtag aaaaattgat agagcactta attctttgcc
    98821 ttatgcagct agagaacaat attttaatga tttattaatc gatgaattac aaagtactaa
    98881 tgaaattgaa aatgtattta gtactaaaca agagattgca catgcgttaa ataaccaagc
    98941 atcagaattt cttaagttca gaggcctcgt ggatcaatat aaagagatag aacttaataa
    99001 aaaaattaaa gttgataatg taagagacat tagagcgatt tatgataaat tagtttcaaa
    99061 tgaaattaac gaacaagata agttagatgg agagctattt cgtaaaaatt ttgtcggtgt
    99121 acatgatggg tcaacgaata aatatataca tgttgggtta caacctgaaa ccaaaattgt
    99181 tgaatatata ggtgaaatgc taacattttt aaaatatttt gatgcgcctc agccgttcaa
    99241 aatcatggct agtcattatc tgtttgaata tatacatcct ttttatgatg gcaatggtag
    99301 agttggaaga tttataattg ccaagctctt gagtgattat tatgataatt atactgcttt
    99361 gacattttca tatgttataa ataggaataa atcgaaatat tacaaggcgt ttatgactgc
    99421 ttcaaatcat ttgaattgcg gtgatttgac ggaatttatt gacacaatgc ttgagttatt
    99481 gatagcagga caagaaagaa tacttgatga attaatacca aaaatggatg cgactgaaaa
    99541 attaacgctt tatttaacta gtcattataa acagatagat tatgaatttt tgtatctcct
    99601 ttcaatggat aaattgtttg gaaataaaag aaatagatta acattaattg atttagaaaa
    99661 catattggga gtaggaagag taaaaattaa taatacaatt aaaaaatttg gtaactactt
    99721 agttaaaatt aaaagtagac caacaattta tgagataagt gatgaatttc taaattcgat
    99781 tataaaataa atgtaatatg tgattcagct atacttattg tatttgtaag attgcgtaat
    99841 tgcttcatta aaaaaatata tttgttgaga gtggtgcatg acaaatgtac tgctcttttt
    99901 gttgtgtatc agtattgtga tgttttaatg cgaatattat atgaatcatt atgaaattta
    99961 ataaaaataa ttgaaataat tatcattttt tctgatatac tgttaaacgg tttggaattt
   100021 ttaagtatac actgtattgg ttgatataac tcaactaata attgcgaaca gggtatttca
   100081 aattggaaag tattatgagc gtgatacata atcaaaattg taggctaaag aacctgagac
   100141 ataaatcaat gttcagtgct ctacaaagtt atattggcag tagttgactg aacgaaaata
   100201 cgcttgtaac aagctttttt caattctagt caaccttgcc ggcggggccc caacatagaa
   100261 gctggcgaaa agacagctta caataatgtg caagttgggg tgggacgacg aaataaattt
   100321 ttcgaaaata tcatttctgt cccactccct tatcatttat gtctcgctct caaatgtaaa
   100381 ttagtaattg ttttggggga gtttgaagtt aaatatttaa caggatttat tttaatatta
   100441 ttgttagaag gaatttttac aaattcagca agtgcaatcg aatattcaga cttacatcat
   100501 aaaagtgaac ttgattccaa gcgtctatat aatgctaagg tgtcatttgc taatccaact
   100561 cagcttgaaa ataaaaaaac aaacgataga ctgttgaagc atgatttgtt atttcatgac
   100621 atgttcgtaa atgatgcttg gaaaaaagat tttaaagttg aattcgaaaa tgaggcactt
   100681 tcaaagaaat ttgtaaataa ggatatcgat atatttgctg gaaattatgg atatggatgt
   100741 catgggggag aaaccaataa aacgctatgt agttatggtg gtgttacttt aagtgacaat
   100801 aataaatacg atgattataa gaatatacct tgtaatttat ggattgacgg acatcaaaca
   100861 ggaatagaac taactgcagt aaaaacgaaa aagaaaattg ttaccattca agaattagat
   100921 gttcaattaa gaaattattt gaatgagaag tataagttgt acgaactagg tggagacatt
   100981 gttaaagggt atgttaaata tcataatgat gatgaaaaaa tgtagaatat gatttttata
   101041 atttaaatgg tgagtatggt catgaggtat taaaaatgta tgctgataat aaaactatca
   101101 atagtgacaa attgcattta gatatctatt tattcaaatc ataatttaag taagttaatc
   101161 attaatgatc tttgacagtg aaatataaag tacctgtcat tttattgtta caaataaaaa
   101221 cagcagtaag gaggctatca ctcagaaaag tcttactgct gttttctatt agaattacct
   101281 ttaatgcaca caggaattcg atacgaaaca aatatgatta actgtgtaat tacaaaataa
   101341 aactactata gcaaaaagaa gataaagacg atgataataa atgcatcgaa tataattttc
   101401 ttgatgtttt tatcaacaac atcaggtaag gacataagta taaatcctag aattagagtg
   101461 tagcgacata tgttcataat tgttgctgta aactcgatat taaatgaaaa ctttaaaaat
   101521 atacttataa ataaaatgac aaacgacgca attgcaataa aactgccgta tgtagcaatc
   101581 tttgttacga gactattttg attattttca gccattgtag aatcctctta tttcatcatt
   101641 attattttaa acatatcatt ttcctgttat ttaataaagt ttcttgacac aattagctga
   101701 tgtaattgat ttgattagtt tttgaaaaat agacaattta gaagcatcga tttccttgtt
   101761 atgagttcat aaataattat ttatgatacc acgttattgt gaatgttttt ttaaaaaata
   101821 aagcaaaagt tttatacagt aacgaaaatc atgatacttg tcgttgtagt gattaaaatg
   101881 tgataaaata acaaatgcta ggatttttta aaagaggtga atcaaaggat gattggtata
   101941 attggtgcca tggaagaaga agtaacaata ttaaaaaata aattaacaca attaagcgaa
   102001 atttcagttg cacatgttaa attttatact ggcattttaa aagatagaga agtagtgatt
   102061 acccaaagcg gcattggaaa agttaatgct gcaatttcta cgacattatt aattaataag
   102121 tttaaaccgg acatcattat taatacaggt tctgctggag ctttagatga aagtttaaat
   102181 gtaggtgacg ttcttataag tgatgatgta aaatatcatg atgcagatgc aacagcattt
   102241 ggttatgaat atggacaagt accacagatg ccggtagcat ttcaatcaag taaaccttta
   102301 atagataaag tatctcaagt tgtacaacaa caacaattaa cagctaaagt aggcttaatt
   102361 gtaagtggtg atagctttat cggtagtgtt gaacaacgcc aaaaaattaa aaaagcattt
   102421 ccaaatgcga tggcggttga aatggaagca actgcaattg cacaaacatg ttatcaattt
   102481 aatgtaccat ttgttgtagt tcgtgcagtt tcagacttag caaatggaga agcggaaatg
   102541 agcttcgaag catttttaga aaaagcagct gtatcatcaa gtcaaactgt tgaagcatta
   102601 gtgtctcaat tataaaaagg taaaggtgag ttaaatgggt ttagttcgca agttttttat
   102661 gccgaattca tatgttcaat caatatttca aattgattta gacaagttag tggacaaagg
   102721 cgttaaaggt attattacag atttagataa tacgctagta ggttgggatg ttaaagaacc
   102781 tacagaacgt gttaaagcat ggtttaagga agctaatgaa aaaggaatca ctattacaat
   102841 cgtgtctaat aataatgagt ctcgtgttgc tagttttagt cagcatttag acatcgattt
   102901 tatttttaaa gcgagaaagc caatggggaa agcgtttgat aaagcaataa ctaagatgaa
   102961 tatcagacca gatcaaactg ttgttatagg tgaccaaatg cttactgatg tatttggtgg
   103021 taatcgtcga ggtttatata caattatggt cgttccagtt aaacgaactg atggctttat
   103081 tactaagttt aataggttaa ttgaaagacg attattacgt catttcagta aaaaaggtta
   103141 tatcacatgg gaggaaaatt gattgtctga cattttaaaa tgtatcggtt gtggtgcgcc
   103201 acttcaatct gaagataaaa ataaacctgg ttttgtacca gagcataata tgtttcgtga
   103261 tgacgtgatt tgcagacgtt gtttccgctt gaaaaattat aatgaagttc aagatgtagg
   103321 attagaaagt gaagactttt taaaattatt atcaggactt gcggataaaa agggtattgt
   103381 cgtcaatgtc gtggatgtat ttgactttga aggatcattt attaatgcag ttaaacgtat
   103441 tgtcggaaac aaaaaaatca ttttagcagc aaataaattg gatttattgc cgaaacaaat
   103501 taataaacgt cgagttaaag aatggttaaa acgaacagca agaaaatatg gtttggaagc
   103561 tgacgatgtc gtattaattt cagctgaaaa aggctggggc atagacgact tattatcatc
   103621 aattgcgaat attcgagaaa atgaagatgt gtatattgta gggacaacga atgttgggaa
   103681 atctacattg attaataaac tgattgaagc tagtgttggt gaaaaagatg tagtaacaac
   103741 ttcaagattt cctggaacaa ctttagatat gatagatatt cctttagatg aaacatcatt
   103801 tatgtatgat acaccaggta ttattcaaga tcatcaaatg acgcatttag ttagtgaaaa
   103861 agaattgaaa attattatgc ctaagaaaga aataaaacaa cgcgtatatc aattaaatga
   103921 ggcgcaaaca ttattcttcg gcggtctagc gcgcatagat tatgtatcag gtggtaaacg
   103981 tccgttagtt tgtttctttt ctaatgactt gaatatacat cgtactaaaa cggagaaggc
   104041 taatgattta tggcgtaatc aacttggcga tttattaacg ccacctggaa atccacaaaa
   104101 ttttgatctt aatgaggtaa aggctgttag acttgaaaca ggcaaagaga aacgcgatgt
   104161 tatgatctct ggtctaggct ttataactat aggaccagga gctaaagtaa tcgttcgtgt
   104221 tcctaaaaat gttgatgttg tattaagaaa ttctatttta taaggtgatt taaaaaatga
   104281 aatttgcagt tatcggaaat cctatttcac attccttgtc gcccgttatg catagagcaa
   104341 attttaattc tttaggatta gatgatactt atgaagcttt aaatattcca attgaagatt
   104401 ttcatttaat taaagaaatt atttcgaaaa aagaattaga tggctttaat atcacaattc
   104461 ctcataaaga gcgtatcata ccgtatttag atcatgttga tgaacaagcg attaatgcag
   104521 gtgcagttaa cactgttttg ataaaagatg gcaagtggat agggtataat acagatggta
   104581 ttggttatgt taaaggattg cacagcgttt atccagattt agaaaatgca tacattttaa
   104641 ttttgggcgc aggtggtgca agtaaaggta ttgcttatga attagcaaaa tttgtaaagc
   104701 ccaaattaac tgttgcgaat agaacgatgg ctcgttttga atcttggaat ttaaatataa
   104761 accaaatttc aatagcagat gctgaaaagt atttagctga attcgatatc gttattaata
   104821 caacaccagc gggtatggct ggaaataacg aaagtattat taatttaaag catctttctc
   104881 ccaatacttt aatgagtgat attgtttata taccgtataa aacacctatt ttagaggaag
   104941 cagagcgcaa gggaaaccat atttataatg gcttagatat gtttgtttac cagggtgcgg
   105001 aaagctttaa aatttggact aataaagatg ctgatattaa ttctatgaaa acagcagttt
   105061 tacaacaatt aaaaggagaa taacatatgc ttactggcaa acaaaaaaga tacttaagaa
   105121 gtttagcaca caatattgat ccgatttttc aaattggaaa aggcggtatc aacgaaaata
   105181 tgattaaaca aatagatgat acgttagaaa acagagaatt gattaaagtg catgtactac
   105241 aaaataactt tgatgataaa aaagaattag ctgaaacatt aagcgaagct acgcgtagtg
   105301 aattagtgca agtgattgga tctatgatag tgatttatag agaatctaaa gaaaataaag
   105361 aaattgaatt gccataataa tgaaaaagat agtactttac ggcggtcagt ttaaccctat
   105421 ccatactgca catatgatag tagctagcga agtatttcat gaattacagc cagatgaatt
   105481 ttatttttta cctagtttta tgtctccatt gaaaaagcac aataatttta tagatgttca
   105541 gcacagatta acaatgatac agatgattat cgacgagctt ggttttggag atatttgcga
   105601 cgatgaaatt aaacgtggtg gtcagagtta tacctatgac acgatcaagg cattcaagga
   105661 gcaacacaaa gacagtgagt tgtactttgt tattgggacg gatcagtata accaactaga
   105721 gaaatggtat caaattgaat acttaaaaga aatggttact tttgtagttg taaatcgaga
   105781 caaaaatagt caaaatgttg aaaatgctat gattgcaatt cagataccta gggtagatat
   105841 aagttcgaca atgattcgac aaagagttag tgaagggaaa tctatccaag ttcttgttcc
   105901 taaatccgtt gaaaactata ttaaggggga aggattatat gaacattgaa aaagcaaaac
   105961 ggcttgcaaa agagaaactg ccagagaaac gttataatca ttctttaaga gttgcagaaa
   106021 cagctattaa attggcagaa atttatgatg gagacactag taaagtagaa ttagcaggtg
   106081 tattacatga tttctgtaag tatgatgatt taggtaaaat gtatcaaatt gttcgacaat
   106141 acgaattagg taatgaccta ctgagttatg gtagtgaaat attgcatggc cctgtgtgtg
   106201 cagcaatcat ggaacatgaa tatggtatca atgatgagga agtattaatg gctatcaaat
   106261 accatactac tggacgtcaa caaatgacaa aaactgaaaa actgattttt attgcagatt
   106321 acatcgaacc tggaagaaca atcccaggag ttgatgatat tcgagatatg gcatacaatc
   106381 aaggtagttt agataagaca atttatgaaa tttctaaacg cacagtacta tttttaatac
   106441 agaaagatat tacggtatat aataagacga ttgactgttt aaattattat aactatagtg
   106501 acgaaagaat aaaggatgat taaatgaatt cacaagaatt attagcaatt gctgtggatg
   106561 caattgacaa taaaaaaggc gaagatacga tttctttaga aatgaaaggt atcagcgata
   106621 tgacagatta ttttgttgta acgcacggaa ataatgaacg acaagttcaa gcgattgcta
   106681 gagcggtgaa agaagtagcc aatgaacaaa atatagaagt aaaacgtatg gaaggataca
   106741 atgaagcgcg ttggatatta attgacttag ctgatgttgt ggtacatgtt ttccataaag
   106801 acgaaagaaa ttattataat attgaaaagt tatatcaaga tgcaccatta gaatcatata
   106861 gtcaggttgc gtattaatta tgtcgcaata tgcagaaatg agcctagtgt acgatcaatt
   106921 gactcaagat caaccatatg aaaaatggtt tgaaattgta aaaaatcact gcaaagatga
   106981 atcaaatatt ttagatattg gatgcggtac tggtagttta acagttcaat tagaagcttt
   107041 aggtaatgtt actggtatgg atttaagtgt tgatatgttg actgttgcag ctcaaaaatc
   107101 agcaaatgta aattggcttg aaggagatat gacatctttt gatttgcaac aacaatttga
   107161 tatcatcact attttttgtg actctctaaa ttatttgcaa gatgaaactg cagtgattga
   107221 aacattcatc aatgtttatc atcatctgac tgattcaggt gtatttattt ttgatgtaca
   107281 tactgtttat aaaatgatga ctttgtttaa taatcaaagt tatattgatg ataaagggga
   107341 cattttttta gcatgggatg ctgtgcaagg agatttacct ttaagtgttt atcatgatat
   107401 gacatttttc attcgacatg aagatgaaac atattcaagg tttgatgagt ctcattttca
   107461 gagaacattt gatgaaaaga catatttgtc ttggttagct caagttggtt ttaaacaagt
   107521 tgaaacattt actgatttta atatagatga acataatgaa gatgcagaaa gattgttttt
   107581 cattgcgaaa aaataaaagt aaaaccactc gctcagacgt gtataaagtt gaggagtggt
   107641 tttattgtat caatttttat tacgctataa agatttttta actcagtgga agttatatat
   107701 tataagtgct gtt
//
LOCUS       DAPSKH010000003        87463 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPSKH010000003 DAPSKH010000000
VERSION     DAPSKH010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 87463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 87463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..87463
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.003"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            161..361
                     /locus_tag="RPH49_000224"
     CDS             161..361
                     /locus_tag="RPH49_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDY5123422.1"
                     /translation="MNNGTVKWFNAEKGFGFIEREDGSDVFVHFSAIAEDGYKSLEEG
                     QKVEFDIVEGDRGEQAANVVKM"
     gene            complement(857..1075)
                     /locus_tag="RPH49_000225"
     CDS             complement(857..1075)
                     /locus_tag="RPH49_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123423.1"
                     /translation="MSEWHINNQSTKPFLIQQAEEQLSIVKPLPNGSFQILTEIDLEN
                     GNVNNIDHSLLVSVDLKALEISIFDAVN"
     gene            complement(1137..1421)
                     /locus_tag="RPH49_000226"
     CDS             complement(1137..1421)
                     /locus_tag="RPH49_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123424.1"
                     /translation="MNELTKEQKYTIAKFYKLYIERSNKGETETVANFFGDAKDAREN
                     YFCDRDYQDFLTNCQILIQNKYLTGEVLDDNIYNISILNKTFIEFEQNFG"
     gene            complement(1509..2078)
                     /locus_tag="RPH49_000227"
     CDS             complement(1509..2078)
                     /locus_tag="RPH49_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123425.1"
                     /translation="MNYIKRTIILLILFVVVSPINSPKTIADNKYSEIQDDKFQLKPG
                     DIIVTKGPVMWGFFGHCSIAIDDKTILQIEGPGDKPTTQSFESFKYNYASGKNDWMKV
                     YRCSYPGAGKKAAEWVKKNYENTNHRYLVTLNLNSKKFTYCTKIIYQAYKFGVSEKSV
                     KSYGLHIISPYAIKDNFIDPYKLRLVKAY"
     gene            complement(2266..2454)
                     /locus_tag="RPH49_000228"
     CDS             complement(2266..2454)
                     /locus_tag="RPH49_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123426.1"
                     /translation="MSLHFAILFWLALIFLVAATFILVLMKKTGKESKKESYLSFTVI
                     LYIFGFAILIYTFIFGVL"
     gene            complement(2483..2743)
                     /locus_tag="RPH49_000229"
     CDS             complement(2483..2743)
                     /locus_tag="RPH49_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123427.1"
                     /translation="MNNILLNAINIVITTTFVIFNILITYNKDLDDLCWLLPGIIICG
                     VILIVSFTIAMITKNWLSEILFFINIVLVLYYIYPIFYSFIG"
     gene            3083..3286
                     /locus_tag="RPH49_000230"
     CDS             3083..3286
                     /locus_tag="RPH49_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDY5123428.1"
                     /translation="MTFYNFIMGFQNDNTPFGILAEHVSEDKAFPRLEERHQVIRAYV
                     MSNYTDHQLIETTNRAISLYMAN"
     gene            complement(3283..3519)
                     /locus_tag="RPH49_000231"
     CDS             complement(3283..3519)
                     /locus_tag="RPH49_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123429.1"
                     /translation="MDNHNQCNYVNPQNVSLDWECFIISKSEMLLDGVPNELINTWLD
                     KDIITPFSIRNDEINFKTKDIWDALIHHNWYYSN"
     gene            3744..4325
                     /locus_tag="RPH49_000232"
     CDS             3744..4325
                     /locus_tag="RPH49_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDY5123430.1"
                     /translation="MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYY
                     ETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYK
                     PEDLFGDRIVPFKGEARQQVEDRIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKL
                     DEALKHNIGNCNILKFEYDNGTFKFVELIDPNL"
     gene            complement(4398..5015)
                     /locus_tag="RPH49_000233"
     CDS             complement(4398..5015)
                     /locus_tag="RPH49_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid transporter"
                     /protein_id="HDY5123431.1"
                     /translation="MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAII
                     TAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQ
                     IMSPMTQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFL
                     LAILGKMVGSIDKTGKLLTIINKISSIIIIIVALMILQKLIQLIF"
     gene            complement(5168..5662)
                     /locus_tag="RPH49_000234"
     CDS             complement(5168..5662)
                     /locus_tag="RPH49_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123432.1"
                     /translation="MIKIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDI
                     LNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINF
                     IINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYD
                     LINK"
     gene            complement(6061..6483)
                     /locus_tag="RPH49_000235"
     CDS             complement(6061..6483)
                     /locus_tag="RPH49_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDY5123433.1"
                     /translation="MAIHYETKATNVGGRKGHVYTDDRALDIDIVPPAQADGKATNPE
                     QLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDPDSESPKLSVSIDATIKN
                     VISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD"
     gene            6631..7347
                     /locus_tag="RPH49_000236"
     CDS             6631..7347
                     /locus_tag="RPH49_000236"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDY5123434.1"
                     /translation="MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENV
                     TVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFTNDLYLNLISDLANINGIDMID
                     IEWREDIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVK
                     LAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIG
                     EAQAPGQIDVTDLKAQVTLY"
     gene            7430..7969
                     /locus_tag="RPH49_000237"
     CDS             7430..7969
                     /locus_tag="RPH49_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="HDY5123435.1"
                     /translation="MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMRE
                     PWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQN
                     DENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTD
                     LEEDMPKAPRKNRNLITLY"
     gene            complement(8119..8439)
                     /locus_tag="RPH49_000238"
     CDS             complement(8119..8439)
                     /locus_tag="RPH49_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDY5123436.1"
                     /translation="MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVE
                     QYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLA
                     ETFK"
     gene            8583..8939
                     /locus_tag="RPH49_000239"
     CDS             8583..8939
                     /locus_tag="RPH49_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDY5123437.1"
                     /translation="MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKT
                     IIANTGVEINKLFNTHGAKYRELDLKNKLQTLSEDEKLELLSSDGMLVKRPLAVMGDK
                     ITLGFKEDQYKETWLA"
     gene            9097..9477
                     /gene="gcvH"
                     /locus_tag="RPH49_000240"
     CDS             9097..9477
                     /gene="gcvH"
                     /locus_tag="RPH49_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDY5123438.1"
                     /translation="MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELP
                     ETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVK
                     VEISDGSQLEALLTAEKYSEMIGE"
     gene            9656..10534
                     /locus_tag="RPH49_000241"
     CDS             9656..10534
                     /locus_tag="RPH49_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1963 domain-containing protein"
                     /protein_id="HDY5123439.1"
                     /translation="MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMDLKEMK
                     EETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDDLPEQQELFPVKEGILQFW
                     ISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAF
                     SIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEP
                     FNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTD
                     LEAMKFDDYMYSWDCS"
     gene            11009..11395
                     /locus_tag="RPH49_000242"
     CDS             11009..11395
                     /locus_tag="RPH49_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDY5123440.1"
                     /translation="MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDM
                     IESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLS
                     KHGFTCKKETPLLPNINNERLVLVNE"
     gene            11388..11684
                     /locus_tag="RPH49_000243"
     CDS             11388..11684
                     /locus_tag="RPH49_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDY5123441.1"
                     /translation="MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEI
                     LQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK"
     regulatory      11742..11845
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            11935..12960
                     /locus_tag="RPH49_000244"
     CDS             11935..12960
                     /locus_tag="RPH49_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDY5123442.1"
                     /translation="MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGK
                     STLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKN
                     IMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPT
                     VLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGK
                     VIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTT
                     EPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVK
                     MEVLRHG"
     gene            12953..13648
                     /locus_tag="RPH49_000245"
     CDS             12953..13648
                     /locus_tag="RPH49_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123443.1"
                     /translation="MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFIL
                     GLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISG
                     PTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPAL
                     VSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQ
                     FIGDWLTNKLDKR"
     gene            13666..14487
                     /locus_tag="RPH49_000246"
     CDS             13666..14487
                     /locus_tag="RPH49_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDY5123444.1"
                     /translation="MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAE
                     ILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKI
                     VSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGV
                     KIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDS
                     IAVESAKDNPYANLIAVKEGNQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK"
     gene            14838..15032
                     /locus_tag="RPH49_000247"
     CDS             14838..15032
                     /locus_tag="RPH49_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDY5123445.1"
                     /translation="MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFV
                     ENAKEKATDFIDKVKGNKGE"
     gene            complement(15266..16117)
                     /locus_tag="RPH49_000248"
     CDS             complement(15266..16117)
                     /locus_tag="RPH49_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDY5123446.1"
                     /translation="MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASIS
                     GIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYL
                     LKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMC
                     ASSAMLLPGISGSFMLLVFGVYGIVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISS
                     KIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLG
                     RITAENE"
     gene            16445..17206
                     /gene="sufC"
                     /locus_tag="RPH49_000249"
     CDS             16445..17206
                     /gene="sufC"
                     /locus_tag="RPH49_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDY5123447.1"
                     /translation="MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKS
                     TLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFM
                     RSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQL
                     MMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVH
                     VMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE"
     gene            17304..18611
                     /gene="sufD"
                     /locus_tag="RPH49_000250"
     CDS             17304..18611
                     /gene="sufD"
                     /locus_tag="RPH49_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDY5123448.1"
                     /translation="MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPK
                     PDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQ
                     VDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYV
                     PKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIIS
                     EVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNL
                     FGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYI
                     KHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMS
                     RGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK"
     gene            18717..19967
                     /locus_tag="RPH49_000251"
     CDS             18717..19967
                     /locus_tag="RPH49_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDY5123449.1"
                     /translation="MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQ
                     VLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTA
                     SINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNI
                     EDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDM
                     QEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLP
                     TKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPP
                     KDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIY
                     NTKEDIDQLINALKQTKEFFSYEF"
     gene            19957..20421
                     /locus_tag="RPH49_000252"
     CDS             19957..20421
                     /locus_tag="RPH49_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDY5123450.1"
                     /translation="MNFNNLDQLYRSVIMDHYKNPRNKGVLDNGSMTVDMNNPTCGDR
                     IRLTFDIEDGIIKDAKFEGEGCSISMASASMMTQAVKGHSLGEAMQMSQEFTKMMLGE
                     DYVITEEMGDIEALQGVSQFPARIKCATLAWKALEKGTVAKEGKAEGTTEEE"
     gene            20572..21969
                     /gene="sufB"
                     /locus_tag="RPH49_000253"
     CDS             20572..21969
                     /gene="sufB"
                     /locus_tag="RPH49_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDY5123451.1"
                     /translation="MAKKAPDVGDYKYGFHDDDVSIFRSERGLTENIVREISNMKNEP
                     EWMLDFRLKSLKLFYKMPMPQWGGDLSELNFDDITYYVKPSEQAERSWDEVPEEIKRT
                     FDKLGIPEAEQKYLAGVSAQYESEVVYHNMEKELEEKGIIFKDTDSALQENEELFKKY
                     FASVVPAADNKFAALNSAVWSGGSFIYVPKNIKLDTPLQAYFRINSENMGQFERTLII
                     ADEGASVHYVEGCTAPVYTTSSLHSAVVEIIVHKDAHVRYTTIQNWANNVYNLVTKRT
                     FVYENGNMEWVDGNLGSKLTMKYPNCVLLGEGAKGSTLSIAFAGKGQVQDAGAKMIHK
                     APNTSSTIVSKSISKNGGKVIYRGIVHFGRKAKGARSNIECDTLILDNESTSDTIPYN
                     EVFNDQISLEHEAKVSKVSEEQLFYLMSRGISEEEATEMIVMGFIEPFTKELPMEYAV
                     EMNRLIKFEMEGSIG"
     gene            22155..22294
                     /locus_tag="RPH49_000254"
                     /pseudo
     CDS             22155..22294
                     /locus_tag="RPH49_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499406.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22300..22614)
                     /locus_tag="RPH49_000255"
                     /pseudo
     CDS             complement(22300..22614)
                     /locus_tag="RPH49_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499407.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            22980..24020
                     /locus_tag="RPH49_000256"
     CDS             22980..24020
                     /locus_tag="RPH49_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDY5123452.1"
                     /translation="MIIAIIILIFISFFFSGSETALTAANKTKFKTEADKGDKKAKGI
                     VKLLEKPSEFITTILIGNNVANILLPTLVTIMALRWGISVGIASAVLTVVIILISEVI
                     PKSVAATFPDKITRLVYPIINICVIVFRPITLLLNKLTDSINRSLSKGQPQEHQFSKE
                     EFKTMLAIAGHEGALNEIETSRLEGVINFENLKVKDVDTTPRINVTAFASNATYEEVY
                     ETVMNKPYTRYPVYEGDIDNIIGVFHSKYLLAWSNKKEDQITNYSAKPLFVNEHNKAE
                     WVLRKMTISRKHLAIVLDEFGGTEAIVSHEDLIEELLGMEIEDEMDKKEKEKLSQQQI
                     QFQQRKNRNVSI"
     gene            24034..25101
                     /locus_tag="RPH49_000257"
     CDS             24034..25101
                     /locus_tag="RPH49_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitronate monooxygenase"
                     /protein_id="HDY5123453.1"
                     /translation="MWNKNRLTQMLSIEYPIIQAGMAGSTTPKLVASVSNSGGLGTIG
                     AGYFNTQQLEDEIDYVRQLTSNSFGVNVFVPSQQSYTSSQIENMNAWLKPYRRALHLE
                     EPVVKITEEQQFKCHIDTIIKKQVTVCCFTFGIPNESIIKRLKEANIKLIGTATSVDE
                     AIANEKAGMDAIVAQGSEAGGHRGSFLKPKNQLPMIGTISLVPQIVDVVSIPVIAAGG
                     IMDGRGVLASIVLGAEGVQMGTAFLTSQDSNASELLRDAIINSKETDTVVTKAFSGKL
                     ARGINNKFIEEMSQYEGDIPDYPIQNELTSSIRKAAANIGDKELTHMWSGQSPRLATT
                     HPANTIMSNIINQINQIMQYK"
     gene            25349..25432
                     /locus_tag="RPH49_000258"
     CDS             25349..25432
                     /locus_tag="RPH49_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123454.1"
                     /translation="MIIIKRKHQAEERRKILIKQKHQTKVR"
     gene            25480..26328
                     /locus_tag="RPH49_000259"
     CDS             25480..26328
                     /locus_tag="RPH49_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDY5123455.1"
                     /translation="MINIGLTGWGDHYSLYEDLERQTDKLKTYAGHFPVVELDATYYA
                     IQPERNILKWIKETPDTFEFVVKIHQALTLHADYKTFADTRQELFDQFKNMLEPLHTQ
                     KKLAMVLVQFPPWFDCNAQNIKYILYVRQQLQAFPMCVEFRHQSWFSDAFKEQTLAFL
                     TEHQIIHAVVDEPQVKDGSVPLVNRITNEIAFVRYHGRNHYGWTKKDMSDQEWRDVRY
                     LYDYNEQELIDLAQKAQILAQKAKKVYVIFNNNSGGHAANNAKTYQRLLNIEYEGLAP
                     QQLKLF"
     gene            26341..27168
                     /locus_tag="RPH49_000260"
     CDS             26341..27168
                     /locus_tag="RPH49_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDY5123456.1"
                     /translation="MLLTITLLVLIGGLSAIIGSIVGIGGGIIIVPTMVYLGVEHGLL
                     HNITTQVAIGTSSVILIVTGLSSSLGYLKTKQVDIKNGSIFLFGLLPGSLLGSFISRY
                     LTFESFNLYFGIFLIFVAILLMVRNKIKPFKIFDKPKYEKTYVDAKGKTYHYSVPPLF
                     AFVTTFLIGILTGLFGIGGGALMTPLMLIVFRFPPHVAVGTSMMMIFFSSVMSSIGHI
                     AQGHVAWGYAIILIISSYFGAKIGVKVNQSIKSDTVVTLLRTVMLLMGIYLIIRALI"
     gene            27195..28514
                     /locus_tag="RPH49_000261"
     CDS             27195..28514
                     /locus_tag="RPH49_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDY5123457.1"
                     /translation="MRLTIYHTNDIHSHLHEYERIKAYMAEHRPRLNHPSLYVDLGDH
                     VDLSAPITEATLGKKNVALLNEAKCDVATIGNNEGMTISHEALNHLYDEAKFIVTCSN
                     VIDESGHLPNNIVSSYIKDIDGVKILFVAATAPFTPFYRALDWIVTDPLESIKEEIEL
                     QRGKFDVLIVLSHCGIFFDETLCQELPEIDVIFGSHTHHYFEHGEINNGVLMAAAGKY
                     GNYLGEVNLTFEAHKVVHKTAKIIPLETLPEVETSFEEEGKTLMSNSVIQHPVVLKRS
                     MNHITEAAYLLAQSVCEYTHAQCAIINAGLLVKDIVKDEVTEYDIHQMLPHPINMVRV
                     RLSGVKLKEIIAKSNKQEYMYEHAQGLGFRGNIFGGYILYNLGYIHSTGRYYLNGEEI
                     EDDKEYVLGTIDMYTFGRYFPILKELPKEYLMPEFLRDIFKEKLLEY"
     gene            28598..29515
                     /gene="lipA"
                     /locus_tag="RPH49_000262"
     CDS             28598..29515
                     /gene="lipA"
                     /locus_tag="RPH49_000262"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDY5123458.1"
                     /translation="MATKNEEILRKPDWLKIKLNTNENYTGLKKMMREKNLNTVCEEA
                     KCPNIHECWGARRTATFMILGAVCTRACRFCAVKTGLPNELDLNEPERVAESVELMNL
                     KHVVITAVARDDLRDAGSNVYAETVRKVRERNPFTTIEILPSDMGGDYDALETLMASR
                     PDILNHNIETVRRLTPRVRARATYDRTLEFLRRSKELQPDIPTKSSIMVGLGETIEEI
                     YETMDDLRANDVDILTIGQYLQPSRKHLKVQKYYTPLEFGKLRKVAMDKGFKHCQAGP
                     LVRSSYHADEQVNEAAKEKQRQGEAQLNS"
     gene            29645..30028
                     /locus_tag="RPH49_000263"
     CDS             29645..30028
                     /locus_tag="RPH49_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDY5123459.1"
                     /translation="MIKVDQHYFELIENYRECFNEEQFIARYSDILDKYDYIVGDYGY
                     DQLRLKGFYKDSNKKAEMSKRFSNIQDYIFEYCNFGCPYFVLRHLSKQEVKKLIEEVH
                     PSDVIDDDNKLQDVKIKPTIQETEH"
     gene            complement(30107..30373)
                     /locus_tag="RPH49_000264"
     CDS             complement(30107..30373)
                     /locus_tag="RPH49_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3055 domain-containing protein"
                     /protein_id="HDY5123460.1"
                     /translation="MIDMYLYDDNEESQVQFVGFVGEHSRYDLMLVHTNRHYGKTLVL
                     NMQTNKFGIIGTDDLKEEGYIAHILGVNAEEGDEITEYLNEVIH"
     gene            30471..30905
                     /locus_tag="RPH49_000265"
     CDS             30471..30905
                     /locus_tag="RPH49_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF86 domain-containing protein"
                     /protein_id="HDY5123461.1"
                     /translation="MYFVDKDKLTQKLAYLQALTDDYHESKHNHYAFERIAQMLIESS
                     VDIGNMIIDAFILRDPGNYKDVIDILELENVITKETQQAINKTVDIRKQFTYDYTALD
                     IKVIMPMFDDALPYYKQFITEVTTFLHQENVPVTAFGKGENQ"
     gene            30905..31690
                     /locus_tag="RPH49_000266"
     CDS             30905..31690
                     /locus_tag="RPH49_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000816183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDY5123462.1"
                     /translation="MKQYKAYLIDLDGTMYMGTDEIDGAKQFIDYLNVKGIPHLYVTN
                     NSTKTPEQVTEKLREMHIDAKPEEVVTSALATADYISEQSPGASVYMLGGSGLNTALT
                     EAGLVIKNDEHVDYVVIGLDEQVTYEKLAIATLGVRNGATFISTNPDVSIPKERGFLP
                     GNGAITSVVSVSTGVSPQFIGKPEPIIMVKALEILGLDKSEVAMVGDLYDTDIMSGIN
                     VGMDTIHVQTGVSTLEDVQNKNVPPTYSFKDLNEAIAELEKYM"
     gene            31717..32676
                     /locus_tag="RPH49_000267"
     CDS             31717..32676
                     /locus_tag="RPH49_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycerate dehydrogenase"
                     /protein_id="HDY5123463.1"
                     /translation="MVKIVVSRKIPDKFYQQLSKLGDVVMWQKSLVPMPKDQFATALR
                     DADACFITLSEQIDTEILAQSPNLKVIANMAVGYDNIDVESATANNVVVTNTPNVLTE
                     TTAELGFTLMLAIARRIVEAEKYVEADAWQSWGPYLLSGKDVFNSTIGIYGMGDIGKA
                     FARRLQGFNTNILYHNRSRHKDAEADFNATYVSFEKLLAESDFIICTAPLTKETHHKF
                     NAEAFEQMKNDAIFINIGRGQIVDETALIDALDNKEILACGLDVLANEPIDHTHPLMG
                     RDNVLITPHIGSASVTTRDNMIQLCINNIEAVMTNQVPHTPVN"
     gene            32931..33041
                     /locus_tag="RPH49_000268"
     CDS             32931..33041
                     /locus_tag="RPH49_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123464.1"
                     /translation="MMTTNYYVESIKLKLNFIMNIDIMNCKKQILKRILY"
     gene            33089..33241
                     /locus_tag="RPH49_000269"
     CDS             33089..33241
                     /locus_tag="RPH49_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDY5123465.1"
                     /translation="MKSKSKQPPNKYVEAFKPYLLTLLYLAIFITLYLIYGSGDTHNN
                     FIYNEF"
     gene            33257..34714
                     /gene="dltA"
                     /locus_tag="RPH49_000270"
     CDS             33257..34714
                     /gene="dltA"
                     /locus_tag="RPH49_000270"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDY5123466.1"
                     /translation="MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRL
                     QGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQPEFVFNT
                     TDESFESLAGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYAS
                     LVQFTEWMLELNKSGNEQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKL
                     LNEMLTATPINIWVSTPSFMEMCLLLPTLNEEQYSSLNEFFFCGEILPHRAAKALVSR
                     FPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERPGAKLSTTDEGELVIEG
                     QSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRME
                     LEEIETQLRQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNSEMTKNIKNDLKSR
                     LPEYMIPRKFEWMEQLPLTSNGKIDRKKIAEVING"
     gene            34711..35925
                     /gene="dltB"
                     /locus_tag="RPH49_000271"
     CDS             34711..35925
                     /gene="dltB"
                     /locus_tag="RPH49_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PG:teichoic acid D-alanyltransferase DltB"
                     /protein_id="HDY5123467.1"
                     /translation="MIPYGDFTFFLIALIALLPVIILGFLGKRSYIYNGVVTAFMIVL
                     IFSSDKHNLFDQKYLSVQLISFIIYVVWQVLLIMFYYHSKPKNNSFSKFVTVMVLSIL
                     PLALVKVLQSTWLGGHQIHFHESKLIEFVGFLGISYVTFKSVQLIMEIRDGSIKEIKV
                     WKLIQFISFFPTISSGPIDRYKRFVKDDKKVPTGNEYRELVLKAIHMIMLGFLYKYIV
                     AYFINTYAIMPLQLDLHGFVNLWLYMYAYSLYLFFDFAGYSLFAIAFSYLFGIKTPPN
                     FDKPFKAKNIKDFWNRWHMTLSFWFRDCIYMRSLFYMSRKKLLKSQFAMSNVAFLINF
                     FIMGIWHGIEVYYIVYGLYHAALFIGYGYYERWRKKHPPRWQNGFTTALSIVITFHFV
                     TFGFLIFSGKLI"
     gene            35943..36179
                     /gene="dltC"
                     /locus_tag="RPH49_000272"
     CDS             35943..36179
                     /gene="dltC"
                     /locus_tag="RPH49_000272"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002433359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     2"
                     /protein_id="HDY5123468.1"
                     /translation="MEFREQVLNLLAEVAENDIVKENPDVEIFEEGIIDSFQTVGLLL
                     EIQNKLDIEVSIMDFDRDEWATPNKIVEALEELR"
     gene            36176..37351
                     /gene="dltD"
                     /locus_tag="RPH49_000273"
     CDS             36176..37351
                     /gene="dltD"
                     /locus_tag="RPH49_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDY5123469.1"
                     /translation="MKLKPFLPILISGAVFIVFLLLPASWFTGLVNEKTVEDNRTTLT
                     DQVLKGTLIQDKLYESNKYYPIYGSSELGKDDPFNPAIALNKHNANKKAFLLGAGGST
                     DLINAVELASQYDKLKGKKLTFIISPQWFTNHGLTNQNFDARMSQTQINQMFQQKNMS
                     TELKRRYAQRLLQFPHVHNKEYLKSYAKNPKETKDSYISGFKENQLIKIEAIKSLFAM
                     DKSPLEHVKPATKPDASWDEMKQKAVEIGKADTTSNKFGIRDQYWKLIQESKRKVRRD
                     YEFNVNSPEFQDLELLVKTMRAAGADVQYVSIPSNGVWYDHIGIDKERRQAVYKKIHS
                     TVVDNGGKIYDMTDKDYEKYVISDAVHIGWKGWVYMDEQIAKHMKGEPQPEVDKPKN"
     gene            complement(37609..37851)
                     /locus_tag="RPH49_000274"
     CDS             complement(37609..37851)
                     /locus_tag="RPH49_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU family protein"
                     /protein_id="HDY5123470.1"
                     /translation="MPTEDTTMFDQVAEVIERLRPFLLRDGGDCSLIDVEDGIVKLQL
                     HGACGTCPSSTITLKAGIERALHEEVPGVIEVEQVF"
     gene            37952..38275
                     /locus_tag="RPH49_000275"
     CDS             37952..38275
                     /locus_tag="RPH49_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YuzD family protein"
                     /protein_id="HDY5123471.1"
                     /translation="MEHVSVVVYGADVICASCVNAPTSKDIYDWLQPLLKRKYPNISF
                     KYTYIDITKDNDNLTDHDLQFIERIEQDELFYPLITMNDEYVADGYIQTKQITRFIDQ
                     KLVNE"
     gene            complement(38334..39398)
                     /locus_tag="RPH49_000276"
     CDS             complement(38334..39398)
                     /locus_tag="RPH49_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5123472.1"
                     /translation="MKNLVLLGGGYGNMRIMSRILTTSLPQDYTVTLVDRMPFHGLKP
                     EFYALAAGTKSDKDVRMKFPNHPQVNTVYGEINDIDLDAQIVSVGNSKIDYDELIIGL
                     GCEDKYHNVPGAEEYTHSIQTLSKARDTFHSISELPEGAKVGIVGAGLSGIELASELR
                     ESRSDLEIYLYDRGPRILRNFPEKLSKYVAKWFAKNNVTVVPNSNINKVEPGKIYNCD
                     EPKDIDLVVWTAGIQPVEVVRNLPIDINSNGRVIVNQYHQVPTYRNVYVVGDCADLPH
                     APSAQLAEVQGDQIADVLKKQWLNEPLPDKMPELKVQGIVGSLGDKQGFAYIMDRTVT
                     GRLASILKSGVLWLYKYHNG"
     gene            39714..39950
                     /locus_tag="RPH49_000277"
     CDS             39714..39950
                     /locus_tag="RPH49_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YuzB family protein"
                     /protein_id="HDY5123473.1"
                     /translation="MNPIVEFCLSNMAKGGDYVFNQLENDPDVDVLEYGCLTHCGICS
                     AGLYALVNGDIVEGDSPEELLQNIYAHIKETWIF"
     gene            39963..40322
                     /locus_tag="RPH49_000278"
     CDS             39963..40322
                     /locus_tag="RPH49_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly accessory protein"
                     /protein_id="HDY5123474.1"
                     /translation="MPTVILTEAAAYEVKDMLKANEMPDGYLKIKVNGGGCTGLTYGM
                     GAEEAPGENDEILEYFGLKVLVDKKDAPVLNGTTIDFKQSLMGGGFQIDNPNAIASCG
                     CGSSFRTAKVAGNPENC"
     gene            40776..41984
                     /locus_tag="RPH49_000279"
     CDS             40776..41984
                     /locus_tag="RPH49_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5123475.1"
                     /translation="MAQDRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYH
                     YEATWLHEASAGTLNYEDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVETNQGIYDF
                     DILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLS
                     ILVGGAGFTGVEFLGELTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHA
                     VSYLEDRGVEFKIATPIVACNEKGFVVEVDGEKQQLNAGTSVWAAGVRGSKLMEESFE
                     GVKRGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIK
                     RILNGESTEEFEYVDRGTVCSLGSHDGVGMVFGKPIAGKKAAFMKKVIDTRAVFKIGG
                     IGLAFKKGKF"
     gene            42115..43590
                     /locus_tag="RPH49_000280"
     CDS             42115..43590
                     /locus_tag="RPH49_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M17 family metallopeptidase"
                     /protein_id="HDY5123476.1"
                     /translation="MNFKLNNTLSNEINTLIIGIPEHLNQLERISFNHIDITESLERL
                     KHQHIIGSKVGKIYTTAFDVQDQTYRLITVGLGNLKARSYQDMLKIWGHLFQYIKSEH
                     IEDTYLLMDSFISKYDQLSDVLMACGIQSERATYEFDHYKSSKKAPFKTNLNLISESL
                     IELDFIHEGISIGQSINLARDFSNMPPNVLTPQTFAEDIVNHFKNTKVKVDVKDYDTL
                     VSEGFGLLQAVGKGSKHKPRLVTITYNGKDKDEAPIALVGKGITYDSGGYSIKTKNGM
                     ATMKFDMCGAANVVGIIEAASRLQLPVNIVGVLACAENMINEASMKPDDVFTALSGET
                     VEVMNTDAEGRLVLADAVYYANQYQPSVIMDFATLTGAAIVALGDDKAAAFESNSKVI
                     LNDILQISSKVDEMVFELPITATERASIKHSDIADLVNHTNGQGKALFAASFVTHFSG
                     QTPHIHFDIAGPATTNKASYNGPKGPTGFMIPTIVQWLKQQ"
     gene            44001..45317
                     /locus_tag="RPH49_000281"
     CDS             44001..45317
                     /locus_tag="RPH49_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter family protein"
                     /protein_id="HDY5123477.1"
                     /translation="MINAVVIAVILMIVLCLCRLNVVISLFISALVGGVVSGMSIEKV
                     INVFGKNIVDGAEVALSYALLGGFAALISYSGITDYLVGKIINAIHAENSRWSRVKVK
                     VTIIIALLAMSIMSQNLIPVHIAFIPIVIPPLLSLFNDLKIDRRLIGLIIGFGLCFPY
                     VLLPYGFGQIFQQIIQSGFAKANHPIEFNMIWKAMLIPSMGYIVGLLIGLYVYRKPRE
                     YETRKISDSDNVTELKPYILIVTIVAILATFLVQTFTDSMIFGALAGVLVFFISRAYN
                     WYELDAKFVEGIKIMAYIGVVILTANGFAGVMNATGDIDELVKTLTSITGDNKLFSII
                     VMYVIGLIVTLGIGSSFATIPIIASLFIPFGASIGLDTMALIALIGTASALGDSGSPA
                     SDSTLGPTAGLNVDGQHDHIRDTCVPNFLFYNIPLMIFGTIAAMVL"
     gene            45336..45710
                     /locus_tag="RPH49_000282"
     CDS             45336..45710
                     /locus_tag="RPH49_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HDY5123478.1"
                     /translation="MTHLLETFEMSIDHQEDGLVVISMPVTDKVKQPFGYLHGGASIA
                     LGETACSLGSANLIDTTKFIPLGLEMNANHIHSAKDGRVTATAEIIHQGKSTHVWDIK
                     IKNDKEQLITVMRGTVAIKPLK"
     gene            complement(45766..46932)
                     /locus_tag="RPH49_000283"
     CDS             complement(45766..46932)
                     /locus_tag="RPH49_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDY5123479.1"
                     /translation="MHWTIIGGGIQGTAIAQKLLSSGLTTDRLTIIDPHETFCQRFNS
                     FTNRIEMPYLRSPIVHHVHPQPFHLKQFAKQHQYTNAFYGPYQRPELTMFMDHIAHAS
                     KQYQLEDCLVQGLVQGLVQTLDKQEDKWHIKLEDGQIITTDCVVIAIGSTNIPFMPDI
                     LKDKQNVNHIFEKEHDQVVYDKTDHIVGSGITAAHLALKLLNHDNDKKIHLWLNKDIE
                     IHDFDADPGWLGPKNMSTFLSTKSMPERNAIVQRERHKGSMPHELYLRLKKHIKNGRI
                     NVHKTPITQISDGLINTENDSVPYQQIMVATGFEQDFMSQPLIKQLIQNYDAPINECN
                     YPVISEKLEWIPNLFVAGCFADLELGPFGRNVMGGRKAAERIEQAFLKLQQYSA"
     gene            complement(47181..47537)
                     /gene="mnhG1"
                     /locus_tag="RPH49_000284"
     CDS             complement(47181..47537)
                     /gene="mnhG1"
                     /locus_tag="RPH49_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit G"
                     /protein_id="HDY5123480.1"
                     /translation="MIKIILISLALIFVIIGALISALAAIGLLRLEDVYSRAHAAGKA
                     STLGAMSLLFGTFLYFIATQGFVNMQLIVAIIFVLITGPLSSHMIMKAAYNIKTPYTK
                     KTKVDEISEDLKDTKL"
     gene            complement(47515..47808)
                     /gene="mnhF1"
                     /locus_tag="RPH49_000285"
     CDS             complement(47515..47808)
                     /gene="mnhF1"
                     /locus_tag="RPH49_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit F"
                     /protein_id="HDY5123481.1"
                     /translation="MNHNVIIVIALIIVVISMLAMLIRVVLGPSLADRVVALDAIGLQ
                     LMAVIALFSILLNIKYMIVVIMMIGILAFLGTAVFSKFMDKGKVIEHDQNHTD"
     gene            complement(47808..48287)
                     /gene="mnhE1"
                     /locus_tag="RPH49_000286"
     CDS             complement(47808..48287)
                     /gene="mnhE1"
                     /locus_tag="RPH49_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit E"
                     /protein_id="HDY5123482.1"
                     /translation="MAVQLVLNFIIAVFWLFVTNSYTTNNFVLGFIFGLVLVYLLHRV
                     LPGRFYVITLYRIIKLVIIFLIELIKANFDVLKIIIKPSIKNEPGFFVYHTDLKKDWQ
                     IVLLSNLITLTPGTVVLGVSDDRTKIYIHAIDFSTKEQEVESIKTSLEKIVREVGEI"
     gene            complement(48289..49785)
                     /gene="mnhD1"
                     /locus_tag="RPH49_000287"
     CDS             complement(48289..49785)
                     /gene="mnhD1"
                     /locus_tag="RPH49_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit D"
                     /protein_id="HDY5123483.1"
                     /translation="MIESNMLVLTLVIPVITAILLVFIGKRPIIKRYVALGGTLLTLV
                     AAIINLANVVKHGPIRVELGSWKAPYSIVFVLDIFSALLIITSIIITAIVILYSYQTI
                     GIERERYYYYFSVLFMLIGIIGAFTTGDIFNLFVFFEVFLMSSYFLLVIGSTKIQLQE
                     TIKYVLVNVVSSSFFVMGVAILYSVVGTLNLADISNKLANLSAHDSGLVNIVFILFIF
                     VFATKAGVFPMFVWLPSAYYAPPIPIIAFFGALLTKVGVYAIARTLSLFFSDNVSFSH
                     YVILFLALLTIIFGCVGAVAYANIKKIILYNVMIAVGVILVGVAMMTESGMIGAIYYT
                     LHDMLVKLALFLLIGIMIKITGTADLRQFGGLIKRYPVLGWSFFIAALSLAGIPPLSG
                     FYGKFFIVQSTFERGFYLSGVIVLLSSLVVLYSVIRIFLQGFFGQPKGYDLNNKVDVK
                     YLTTIAIVAVVITVLYGLSADYLYPMVKAGAETFYNPSTYVKAVLGGK"
     gene            complement(49778..50119)
                     /gene="mnhC1"
                     /locus_tag="RPH49_000288"
     CDS             complement(49778..50119)
                     /gene="mnhC1"
                     /locus_tag="RPH49_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit C"
                     /protein_id="HDY5123484.1"
                     /translation="MEIIMIFVSGILTAISVYLVLSKSLIRIVMGTTLLTHAANLFLI
                     TMGGLKHGTVPIYEANVKSYVDPIPQALILTAIVIAFATTAFFLVLAFRTYKELGTDN
                     VESMKGVPEDD"
     gene            complement(50119..50547)
                     /gene="mnhB1"
                     /locus_tag="RPH49_000289"
     CDS             complement(50119..50547)
                     /gene="mnhB1"
                     /locus_tag="RPH49_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit B"
                     /protein_id="HDY5123485.1"
                     /translation="MNRQQNDLILQFAAVIIFFMVMVFGFSLFLAGHYTPGGGFVGGL
                     LFASSLVIITIAFDIETMRKIFPLDFKILIGIGLVFCIATPIASWFLGKNFFTHVTFD
                     IPLFILEPVHMTTAVFFDFGVLCAVVGTVMTIIISIGENE"
     gene            complement(50540..52945)
                     /gene="mnhA1"
                     /locus_tag="RPH49_000290"
     CDS             complement(50540..52945)
                     /gene="mnhA1"
                     /locus_tag="RPH49_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh1 subunit A"
                     /protein_id="HDY5123486.1"
                     /translation="MSLLHIAVILPLIFALIIPILYRFFKRIHLGWFVLPVPIVIFIY
                     MLTLIKTTMSGNTVMKTLNWMPHFGMNFDLYLDGLGLLFSLLISGIGSLVVLYSIGYL
                     SKSEQLGNFYCYLLLFMGAMLGVVLSDNVIILYLFWELTSFSSFLLISFWRERQASIY
                     GAQKSLIITVFGGLSLLGGIILLAIPTQSFSIQYMIQHASEIQNSPFFIFAMILIMIG
                     AFTKSAQFPFYIWLPDAMEAPTPVSAYLHSATMVKAGLYLIARMTPIFAASQGWIWTV
                     TLVGLITLFWASLNATKQQDLKGILAFSTVSQLGMIMAMLGIGAISYHYQGDDSKIYA
                     AAFTAAIFHLINHATFKGALFMITGAVDHSTGTRDVKKLGGLLTIMPISFTITVITAL
                     SMAGVPPFNGFLSKESFLETTFTASQANLFSVDTLGYLFPIIGIVGSVFTFVYSNKFI
                     MHIFFGQYKPEQLPKKAHEVSILMLLSPAILATLVIVFGLFPGILTNSIIEPATSSIN
                     HTVIDDVEFHMFHGLTPAFLSTLVIYILGILLIVTFSYWVKLLQRQPGKLTFNYWYNR
                     SANVIPNYSEKMTNSYVTDYSRNNLVIIFGTLILLTFVTIFSVPFNINFKDVSPIRIF
                     EVCIVILLLSAAFLILFAKSRLFSIIMLSAVGYAVSVLFIFFKAPDLALTQFVVESIS
                     TALFLLCFYHLPNLNRYNEKRSFQLTNALIAGGVGLSVIIIGLIAYGNRHFESISKFY
                     QEHVYDLAHGKNMVNVILVDFRGMDTLFESSVLGIAGLAVYTMIKLRKKRQTQGNEVK
                     NHE"
     gene            complement(53076..53459)
                     /locus_tag="RPH49_000291"
     CDS             complement(53076..53459)
                     /locus_tag="RPH49_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase-associated lipoprotein B"
                     /protein_id="HDY5123487.1"
                     /translation="MKLYRFSHKTGSYGVTIVEENGDDVLVKVEQVIKHPKQGDLHNP
                     TETEGVFFHERKALSHFEKRYTKRSQLRDFNVDVLRYEDSLQQAITDLETKLKAQQTK
                     HAEMSLASLARLKEDYSLQYKENFK"
     gene            53523..54116
                     /locus_tag="RPH49_000292"
     CDS             53523..54116
                     /locus_tag="RPH49_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDY5123488.1"
                     /translation="MANYPQLNKEVQQGEIKVVMHTNKGDMTFKLFPNIAPKTVENFV
                     THAKNGYYDGITFHRVINDFMIQGGDPTATGMGGESIYGGAFEDEFSLNAFNLYGALS
                     MANSGPNTNGSQFFIVQMKEVPQNMLSQLADGGWPQPIVDAYGEKGGTPWLDQKHTVF
                     GQIIDGETTLEDIANTKVGPQDKPLHDVVIESIDVEE"
     gene            54532..54909
                     /locus_tag="RPH49_000293"
     CDS             54532..54909
                     /locus_tag="RPH49_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDY5123489.1"
                     /translation="MNNYKIGQHIKVRVTGIQPYGAFVETPNHTEGLIHISEIMDDYV
                     HNLKKFLSEGQIVKAKILSIDDEGKLNLSLKDNDYFKNYERKKEKQSVLDEIRETEKY
                     GFQTLKERLPIWIKQSKQAIRND"
     gene            55271..56398
                     /locus_tag="RPH49_000294"
     CDS             55271..56398
                     /locus_tag="RPH49_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDY5123490.1"
                     /translation="MKSKYEPLFDKVELPNGVELRNRFVLAPLTHISSNDDGTISDVE
                     LPYIEKRSQDVGITINAASNVSDVGKAFPGQPSIAHDSDIEGLKRLATAMKKNGAKAL
                     VQIHHGGAQALPELTPGGDVVAPSPISLKSFGQKQEHSAREMTNEEIEQAIKDFGEAT
                     RRAIEAGFDGVEIHGANHYLIHQFVSPYYNSRNDVWANQYKFPVAVIEEVLKAKEAYG
                     NKDFIVGYRLSPEEAESPGITMEITEELVNKISHMPIDYIHVSMMDTHATTREGKYAG
                     QERLPLIHKWINGRMPLIGIGSIFTADEALDAVENVGVDLVAIGRELLLDYQFIEKIK
                     DGREDEIINYFDPEREDNHHLTPNLWHQFNEGFYPLPRKDK"
     gene            56706..57896
                     /locus_tag="RPH49_000295"
     CDS             56706..57896
                     /locus_tag="RPH49_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine--oxo-acid transaminase"
                     /protein_id="HDY5123491.1"
                     /translation="MTKSEKIIELTNHYGAHNYLPLPIVISEAEGVWVKDPEGNKYMD
                     MLSAYSAVNQGHRHPKIIQALKDQADKVTLVSRAFHSDNLGEWYEKICKLAGKDKALP
                     MNTGAEAVETALKAARRWAYDVKGIEPNKAEIIAFNGNFHGRTMAPVSLSSEAEYQRG
                     YGPLLDGFRKVDFGDVDALKAAINENTAAVLVEPIQGEAGINIPPEGYLKAIRELCDE
                     HNVLFIADEIQAGLGRSGKLFATDWDNVKPDVYILGKALGGGVFPISVVLADKEVLDV
                     FTPGSHGSTFGGNPLACAASIAALDVIVDEDLPGRSLELGDYFKEQLKQIDHPSIKEV
                     RGRGLFIGVELNESARPYCEALKEEGLLCKETHDTVIRFAPPLIITKEELDLALEKIR
                     HVFQ"
     gene            58005..59249
                     /locus_tag="RPH49_000296"
     CDS             58005..59249
                     /locus_tag="RPH49_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu/Leu/Phe/Val dehydrogenase"
                     /protein_id="HDY5123492.1"
                     /translation="MTENNNLVTSTQGIIKEALHKLGFDEGMYDLIKEPLRMLQVRIP
                     VRMDDGTVKTFTGYRAQHNDAVGPTKGGVRFHPDVDEEEVKALSMWMTLKCGIVNLPY
                     GGGKGGIVCDPRQMSIHEVERLSRGYVRAISQFVGPNKDIPAPDVFTNSQIMAWMMDE
                     YSALDKFNSPGFITGKPIVLGGSHGRDRSTALGVVIAIEQAAKRRNMQIEGAKVVIQG
                     FGNAGSFLAKFLYDLGAKIVGISDAYGALHDPNGLDIDYLLDRRDSFGTVTNLFEETI
                     SNKELFELDCDILVPAAISNQITEDNAHDIKASIVVEAANGPTTPEATRILTERGILL
                     VPDVLASAGGVTVSYFEWVQNNQGYYWSEEEVNEKLREKLEAAFDTIYELSQNRKIDM
                     RLAAYIIGIKRTAEAARYRGWA"
     gene            complement(59531..60460)
                     /locus_tag="RPH49_000297"
     CDS             complement(59531..60460)
                     /locus_tag="RPH49_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDY5123493.1"
                     /translation="MTNSSKSFTKFMAASAVFTMGFLSVPTAGAEQTNQIANKPQAIQ
                     WHTNLTNERFTTIAHRGASGYAPEHTFQAYDKSHNELKASYIEIDLQRTKDGHLVAMH
                     DETVNRTTNGHGKVEDYTLDELKQLDAGSWFNKKYPKYARASYKNAKVPTLDEILERY
                     GPNANYYIETKSPDVYPGMEEQLLASLKKHHLLNNNKLKNGHVMIQSFSDESLKKIHR
                     QNKHVPLVKLVDKGELQQFNDQRLKEIRSYAIGLGPDYTDLTEQNTHHLKDLGFIVHP
                     YTVNEKADMLRLNKYGVDGVFTNFADKYKEVIK"
     gene            complement(60702..62081)
                     /gene="argH"
                     /locus_tag="RPH49_000298"
     CDS             complement(60702..62081)
                     /gene="argH"
                     /locus_tag="RPH49_000298"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDY5123494.1"
                     /translation="MSNKAWGGRFEVQPEEWVDDFNASITFDQTLIDQDIEGSIAHAT
                     MLANQGIISQQDSEQIIQGLKSIQHDYHQDQIQFSASLEDIHLNIEHELIKRIGDAGG
                     KLHTGRSRNDQVATDMHLYTKKQVQDIIALIKSLQSVIVDIASNNVDTIMPGYTHLQR
                     AQPISFAHNIMTYFWMLQRDQQRFEDSLKRIDINPLGAAALSGTTYPIDRHETTALLN
                     FGSLYENSLDAVSDRDYIIETLHNISLTMVHLSRFAEEIIFWSTDEAKFITLSDAFST
                     GSSIMPQKKNPDMAELIRGKVGRTTGHLMSMLMTLKGLPLAYNKDMQEDKEGLFDAVH
                     TIKGSLRIFEGMIQTMTINKEQLNQTVKEDFSNATELADYLVTKNIPFRTAHEIVGKI
                     VLECIQQGHYLLDVPLATYQQHHSSIDADIYDYLQPENCLKRRQSYGSTGQSSVKQQL
                     DVAKQLLSQ"
     gene            complement(62071..63276)
                     /locus_tag="RPH49_000299"
     CDS             complement(62071..63276)
                     /locus_tag="RPH49_000299"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDY5123495.1"
                     /translation="MKEKIVLAYSGGLDTSVAVQWLIDKGYDVVACCLDVGEGKDLDI
                     VYKKALDMGAVECHIIDATKEFSDEYVSYAIKGNLMYENAYPLVSALSRPLIAKKLVE
                     IAEKTNSVGIAHGCTGKGNDQVRFEVAIKALNPSLKAFAPVREWAWSREEEIDYAIKH
                     NIPVSINHDSPYSIDQNLWGRANECGILEDPYAAPPEDAFDLTNALEETPDTADEIIL
                     TFDKGIPVQIDGKTYELDDLILTLNALAGKHGIGRIDHVENRLVGIKSREIYEAPAAE
                     VILKAHKALETITLTKDVAHFKPIIEKQFAEQLYNGLWFSPLTDSLKLFIDSTQQYVS
                     GDVRIKLFKGNTIVNGRKSPYTLYDEKLATYTKEDAFNQDAAVGFIDIYGLPTQVNAM
                     LHGGYSNEQ"
     gene            63627..64958
                     /locus_tag="RPH49_000300"
     CDS             63627..64958
                     /locus_tag="RPH49_000300"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDY5123496.1"
                     /translation="MTHIQLDFSKTLEFFGEHELKQQQEIVKSIHKTIHEGTGAGSDF
                     LGWVDLPVDYDKEEFSRIVEASKRIKENSDVLVVIGIGGSYLGARAAIEMLTSSFRNS
                     NEYPEIVFVGNHLSSTYTKELVDYLADKDFSVNVISKSGTTTEPAVAFRLFKQLVEER
                     YGKEEAQKRIFATTDKEKGALKQLATNEGYETFIVPDDVGGRYSFLTAVGLLPIATAG
                     INIEAMMIGAAKAREELSSDKLEENIAYQYATIRNILYAKGYTTEMLINYEPSMQYFN
                     EWWKQLFGESEGKDFKGIYPSSANYTTDLHSLGQYVQEGRRFLFETVVKVNHPKYDIT
                     IEKDSDDLDGLNYLAGKTIDEVNTKAFEGTLLAHTDGGVPNMVVNIPQLDEETFGYVV
                     YFFELACAMSGYQLGVNPFNQPGVEAYKQNMFALLGKPGFEDLKKELEERL"
     gene            65283..65858
                     /locus_tag="RPH49_000301"
     CDS             65283..65858
                     /locus_tag="RPH49_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDY5123497.1"
                     /translation="MSFHQVEEWFEIFRQFGYLPGFILLYIRAIIPVFPLALYILINI
                     QAYGPILGILISWLGLISGTFTVYLICKRWVNTERMQRIKQRTAVQRLISFIDRQGLI
                     PLFILLCFPFTPNTLINFVASLSHIRPKYYFIVLASSKLVSTIILGYLGKEITTILTQ
                     PLRGILMLVVLVVFWIVGKKLEQHFMGSKKE"
     gene            65863..66387
                     /gene="lepB"
                     /locus_tag="RPH49_000302"
     CDS             65863..66387
                     /gene="lepB"
                     /locus_tag="RPH49_000302"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDY5123498.1"
                     /translation="MKKVVKYLISLILAIIIVLFVQTFVIVGHVIPNNDMSPTLNKGD
                     RVIVNKIKVTFNQLNNGDIITYRRGNEIYTSRIIAKPGQSMAFRQGQLYRDDRPVDAS
                     YAKNRKIKDFSLRNFKELDGDIIPPNNFVVLNDYDNNQHDSRQFGLIDKKDIIGNISL
                     RYYPFSKWTIQFKS"
     gene            66403..66978
                     /gene="lepB"
                     /locus_tag="RPH49_000303"
     CDS             66403..66978
                     /gene="lepB"
                     /locus_tag="RPH49_000303"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDY5123499.1"
                     /translation="MKKELLEWIISIAVAFVILFIVGKFIVTPYMIKGESMDPTLKDG
                     ERVAVNIIGYKTGGLEKGNVVVFHANKNDDYVKRVIGVPGDKVEYKNDTLYVNGKKQD
                     EPYLNYNLKHKQGDYITGTFQVKDLPNANPKSNVIPKGKYLVLGDNREVSKDSRAFGL
                     IDEDQIVGKVSFRFWPFSEFKHNFNPENTKN"
     gene            67138..70614
                     /gene="addB"
                     /locus_tag="RPH49_000304"
     CDS             67138..70614
                     /gene="addB"
                     /locus_tag="RPH49_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddB"
                     /protein_id="HDY5123500.1"
                     /translation="MTLHAYLGRAGTGKSTKMLTEIKQKMKQDPLGDPIILIAPTQST
                     FQLEQAFVNDPELNGSLRTEVLHFERLSHRIFQEVGSYSEQKLSKAATEMMIYNIVQE
                     QQKYLKLYQSQAKYYGFSEKLTEQIQDFKKYAVTPEHLEHFIADKNMQTRTKNKLEDI
                     ALIYREFEQRIQNEFITGEDSLQYFIDCMPKSEWLKRADIYIDGFHNFSTIEYLIIKG
                     LIKYAKSVTIILTTDGNHDQFSLFRKPSEVLRHIEEIANELNISIERQYFKQLYRFNN
                     QDLKHLEQEFDALQINRVACQGHINILESATMREEINEIARRIIVDIRDKQLRYQDIA
                     ILYRDESYAYLFDSILPLYNIPYNIDTKRSMTHHPVMEMIRSLIEVIQSNWQVNPMLR
                     LLKTDVLTASYLKSAYLVDLLENFVLERGIYGKRWLDDELFNVEHFSKMGRKAHKLTE
                     DERNTFKQVVKLKKDVIDKILHFEKQMSQAETVKDFATAFYESMEYFELPNQLMTERD
                     ELDLNGNHEKAEEIDQIWNGLIQILDDLVLVFGDEPMSMERFLEVFDIGLEQLEFVMI
                     PQTLDQVSIGTMDLAKVDNKQHVYLVGMNDGTMPQPVTASSLITDEEKKYFEQQANVE
                     LSPTSDILQMDEAFVCYVAMTRAKGDVTFSYSLMGSSGDDKEISPFLNQIQSLFNQLE
                     ITNIPQYHEVNPLSLMQHAKQTKITLFEALRAWLDDEIVADSWLDAYQVIRDSDHLNQ
                     GLDYLMSALTFDNETVKLGETLSKDLYGKEINASVSRFEGYQQCPFKHYASHGLKLNE
                     RTKYELQNFDLGDIFHSVLKYISERINGDFKQLDLKKIRQLTNEALEQILPKVQFNLL
                     NSSAYYRYLSRRIGAIVETTLSALKYQGTYSKFMPKHFETSFRRKPRTNDELIAQTLT
                     TTQGIPINIRGQIDRIDTYTKNDTSFVNIIDYKSSEGSATLDLTKVYYGMQMQMMTYM
                     DIVLQNKQRLGLTDIVKPGGLLYFHVHEPRIKFKSWADIDEDKLEQDLIKKFKLSGLV
                     NADQTVIDALDIRLEPKFTSDIVPVGLNKDGSLSKRGSQVADEATIYKFIQHNKENFI
                     ETASNIMDGHTEVAPLKYKQKLPCAFCSYQSVCHVDGMIDSKRYRTVDETINPIEAIQ
                     NININDEFGGEQ"
     gene            70615..74268
                     /gene="addA"
                     /locus_tag="RPH49_000305"
     CDS             70615..74268
                     /gene="addA"
                     /locus_tag="RPH49_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDY5123501.1"
                     /translation="MTIPEKPQGVIWTDAQWQSIYATGQDVLVAAAAGSGKTAVLVER
                     IIQKILRDGIDVDRLLVVTFTNLSAREMKHRVDQRIQEASIADPANAHLKNQRIKIHQ
                     AQISTLHSFCLKLIQQHYDVLNIDPNFRTSSEAENILLLEQTIDEVIEQHYDILDPAF
                     IELTEQLSSDRSDDQFRMIIKQLYFFSVANPNPTNWLDQLVTPYEEEAQQAQLIQLLT
                     DLSKVFITAAYDALNKANDLFSMMDGVDKHLAVIEDERRLMGRVLEGGFIDIPYLTGH
                     EFGARLPNVTAKIKEANEMMVDALEDAKLQYKKYKSLIDKVKSDYFSREADDLKADMQ
                     QLAPRVKYLARIVKDVMSEFNRKKRSKNILDFSDYEHFALQILTNEDGSPSEIAESYR
                     QHFQEILVDEYQDTNRVQEKILSCIKTGAEHNGNLFMVGDVKQSIYKFRQADPSLFIE
                     KYQRFTINGDGTGRRIDLSQNFRSRKEVLSTTNYIFKHMMDEQVGEVNYDESAQLYYG
                     APYDESDHPVNLKVLVEADQEHSDLTGSEQEAHFIVEQVKDILEHQKVYDMKTGSYRS
                     ATYKDIVILERSFGQARNLQQAFKNEDIPFHVNSREGYFEQTEVRLVLSFLRAIDNPL
                     QDIYLVGLMRSVIYQFKEDELAQIRILSPNDDYFYQSIVNYINDEVADAILVDKLKMF
                     LSDIQSYQQYSKDHPVYQLIDKFYNDHYVIQYFSGLIGGRGRRANLYGLFNKAIEFEN
                     SSFRGLYQFIRFIDELIERGKDFGEENVVGPNDNVVRMMTIHSSKGLEFPFVIYSGLS
                     KDFNKRDLKQPVILNQQFGLGMDYFDVDKEMAFPSLASVAYKAVAEKELVSEEMRLVY
                     VALTRAKEQLYLIGRVKNDKSLLELEQLSISGEHIAVNERLTSPNPFHLIYSILSKHQ
                     SASIPDDLKFEKDIAQVEDSSRPNVNISIIYFEDVSTETILDNNEYRSVNQLETMQNG
                     NEDVKAQIKHQLDYQYPYVNDTKKPSKQSVSELKRQYETEESGTSYERVRQYRIGFST
                     YERPKFLSEQGKRKANEIGTLMHTVMQHLPFKKERISEVELHQYIDGLIDKHIIEADA
                     KKDIRMDEIMTFINSELYSIIAEAEQVYRELPFVVNQALVDQLPQGDEDVSIIQGMID
                     LIFVKDGVHYFVDYKTDAFNRRRGMTDEEIGTQLKNKYKIQMKYYQNTLQTILNKEVK
                     GYLYFFKFGTLQL"
     gene            74432..75334
                     /locus_tag="RPH49_000306"
     CDS             74432..75334
                     /locus_tag="RPH49_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDY5123502.1"
                     /translation="MKFLSFKYNDKTSYGVKVKREDAVWDLTQVFADFAEGDFHPKTL
                     LAGLQQNHTLDFQEQVRKAVVAAEDSGKAEDYKISFNDIEFLPPVTPPNNVIAFGRNY
                     KDHANELNHEVERLYVFTKAASSLTGDNATIPNHKDITDQLDYEGELGIVIGKSGEKI
                     PKALALDYVYGYTIINDITDRKAQSEQDQAFLSKSLTGGCPMGPYIVTKDELPLPENV
                     NIVTKVNNEIRQDGNTGEMILKIDELIEEISKYVALHPGDIIATGTPAGVGAGMQPPK
                     FLQPGDEVKVTIDNIGTLTTYIAK"
     gene            75659..76048
                     /locus_tag="RPH49_000307"
     CDS             75659..76048
                     /locus_tag="RPH49_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YisL family protein"
                     /protein_id="HDY5123503.1"
                     /translation="MLHLHILSWVLAIILFIATYLNISKNQGGSPFFKPLHMILRLFM
                     LLTLISGFWILIQSFMNGGANHMLLTLKMLCGVAVVGLMEVSIAKRKRHEQSHTMFWI
                     TIALIIITMVLGVILPLGPISKLFGIG"
     gene            complement(76219..77535)
                     /locus_tag="RPH49_000308"
     CDS             complement(76219..77535)
                     /locus_tag="RPH49_000308"
                     /EC_number="1.8.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-disulfide reductase"
                     /protein_id="HDY5123504.1"
                     /translation="MPKIVVVGAVAGGATCASQIRRLDKESDIIIFEKDRDMSFANCA
                     LPYVIGEVVEDRKYALAYTPEKFYDRKQITVKTYHEVIAINDERQTVTVLNRKTNEQF
                     EESYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVS
                     LEVLENLYERGLHPTLIHRSDKINKLMDTDMNQPILDELDKREIPYRLNEEIDAINGN
                     EITFKSGKVEHYDMIIEGVGTHPNSKFIESSNIKLDRKGFIPVNDKFETNVPNIYAIG
                     DIATSHYRHVDLTASVPLAWGAHRAASIVAEQIAGNDTIEFKGFLGNNIVKFFDYTFA
                     SVGVKPNELKQFDYKMVEVTQGAHANYYPGNSPLHLRVYYDTSNRQILRAAAVGKEGA
                     DKRIDVLSMAMMNQLTVDELTEFEVAYAPPYSHPKDLINMIGYKAK"
     gene            complement(77587..78411)
                     /locus_tag="RPH49_000309"
     CDS             complement(77587..78411)
                     /locus_tag="RPH49_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDY5123505.1"
                     /translation="MQPHLICLDLDGTLLNDNKEISSYTKQVLNELQQRGHQIMIATG
                     RPYRASQMYYHELNLTTPIVNFNGAYVHHPKDKNFKTCHEILDLGIAQNIIQGLQQYQ
                     VSNIIAEVKDYVFINNHDPRLFEGFSMGNPRIQTGNLLVHLKESPTSILIEAEESKIP
                     EIKNMLTHFYADHIEHRRWGAPFPVIEIVKLGINKARGIEQVRQFLNIDRNNIIAFGD
                     EDNDIEMIEYARHGVAMENGLQELKDVANNITFNNNEDGIGRYLNDFFNLNIRYYC"
     gene            78525..78833
                     /locus_tag="RPH49_000310"
     CDS             78525..78833
                     /locus_tag="RPH49_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDY5123506.1"
                     /translation="MEEALKDSILGALEMVIDPELGIDIVNLGLVYKVNVDDEGVCTV
                     DMTLTSMGCPMGPQIIDQVKTVLAEIPEIQDTEVNIVWSPPWTKDMMSRYAKIALGVS
                     "
     gene            79488..81302
                     /locus_tag="RPH49_000311"
     CDS             79488..81302
                     /locus_tag="RPH49_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDY5123507.1"
                     /translation="MNKTKGFTKYKKMRYMPGLDGLRAIAVLGIIIYHLNKQWLTGGF
                     LGVDTFFVISGYLITSLLLKEYDDTGIIKLKSFWIRRLKRLLPAVIVLLMVVGTATLL
                     LKSDNIIRVKHDIIAAIFYVSNWWYIAKDVNYFEQFSFMPLKHLWSLAIEEQFYIFFP
                     VILVTLLLTIKKRYKIGFIFLGVSIISLGLMMFIYSINGDHSRVYFGTDTRLQTLLLG
                     VILAFLWPPFKLKNDPPKVVKYVIDSIGSLSFIILILLFFIINDETNWIYDGGFYLIS
                     ILTLFIIASVVHPSTWIAKIFSNPVLVFIGKRSYSLYLWHFAVISFVHSYYVDGQIPV
                     YVYFIDISLTIIFAELSYRFIETPFRKEGIKALNWRPSYIPQFIRMAIVVTLLIPFML
                     ILVGAFNKYGKDIIGEKANSFDTTIEDNYLMRIAPIDNIHIDGLVSEKKKESSDVYNN
                     IKPLLIGDSVMVDIGESFKSSVPKSRIDGKVGRQLYQTLPLVKANYSQYKKSSDQVVL
                     ELGTNGDFTVKQLDDLLNQFGKAKIYLVNTRVPRIYEANVNRLLADAAKRKSNVTLID
                     WYKRSQGHSEYFAPDGVHLEYKGVLALKDEILKALKKK"
     gene            81506..84115
                     /gene="clpB"
                     /locus_tag="RPH49_000312"
     CDS             81506..84115
                     /gene="clpB"
                     /locus_tag="RPH49_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDY5123508.1"
                     /translation="MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESES
                     LYKSILERANIEVDQLNKAYEDKLNTYASVEGDNIQYGQYISQQANQLITKAESYMKE
                     YEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
                     AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGL
                     AQRIVKKDVPESLLDKTVFELDLSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFI
                     DEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYREYIEKDSALERRFQK
                     VAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDL
                     VDQACATIRTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANE
                     KEKQAALQSRVESEKEKIANLQEKRAQLDESRQALEDAQTNNNLEKAAELQYGTIPQL
                     EKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETEREKLLHL
                     SDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAA
                     SLFDSEKHMIRIDMSEYMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDE
                     VEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIMTSNIGSQVLLENVKETGEIT
                     ESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRIS
                     IEVSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNS
                     DNNLTFNVEKIHE"
     gene            complement(84174..85043)
                     /locus_tag="RPH49_000313"
     CDS             complement(84174..85043)
                     /locus_tag="RPH49_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5123509.1"
                     /translation="MNLDWYYTFVILAKTLNYRLASEEINLTIPSIHKQIKNLEQHLN
                     VKLFETYKNQIILTEDGHTFLPIAQSFIEQYESGIKHIQLKKTMFQSKLNVVVSSYIA
                     TFIMPKFLKSFFNEHPFIDVSLHVKNENIEKDINNHTYDIGISRNQPKLREVHSEKVC
                     EGKIVLIAPNKENNHLLTEASLFEKYKIISDNHPEYWSSLKNNILNIYEKAQFLSIND
                     VHTSIKLIEMNQGISFLPIYITTDSDYNISVINTKILQAPISFTYIYSKKESPEILAF
                     IRSFKKYIANEQL"
     gene            85153..86298
                     /locus_tag="RPH49_000314"
     CDS             85153..86298
                     /locus_tag="RPH49_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDY5123510.1"
                     /translation="MIRIQDNTIRDGMQQSNVRKSIIVKKEVLQEINKISINSVEVGM
                     CTTFEDEYNIHQYREILNNDKEIVVLTRLDENEINKILNLKIHNLAVKILLPISDLHI
                     KEKLNFTSEYYNERINKCLNMIKVNQVAIDICFEDATRCSLEKLCEYMEMISKFPIRT
                     VTFADTVGCSTPFEYGNIFKEFVKKYPNITFSAHCHNDLGLATANTFAAILNGAQQIE
                     TTFLGIGERAGNASIEEIIAILTKKQIVMTSLNLPDIYKTSMNISKILDIRLAENKPV
                     IGKNIFKHESGIHQDGTNKNISMYQYILPSDLGLKNSKAVQFPISNISSKKILKNKFK
                     SIVHPKDIEENISFYKLINKFIPEVVPEDTADLLQVIKGRSKDGNFK"
     gene            86282..86923
                     /locus_tag="RPH49_000315"
     CDS             86282..86923
                     /locus_tag="RPH49_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase"
                     /protein_id="HDY5123511.1"
                     /translation="MEILNESVESFEKLYLQLQNSYPIIVPTDTNYNLCSLPNNKICI
                     DRIFKYKKRSKDKPLSLFIDEPEDWKLYGENKNVELVDKLVNIFWPGPLNIILKNKTN
                     YNYMLNNSDSIAIGCVQNKTMRNLISYIQSPIAITSANISGTADDILITENEAIKHMG
                     NNVNYMLRSKNKSKYKSSSTIIKVTGNKIELLREGDIKFEEIKAKLGSGIQYE"
     gene            86916..>87463
                     /locus_tag="RPH49_000316"
     CDS             86916..>87463
                     /locus_tag="RPH49_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123512.1"
                     /translation="MNKLILGIYLYRILSRAYFYLPFLLIYFLAQNYSIMQLEILMAT
                     YGVAAFLFGLYKEKIFRIYQIKDAYKLIVSEVFKIIGLILLLYPSHFYILLVAQLLLG
                     LSYSIMAGVDTSIIKMNIKNHKLIQNKSNGYMFLSLLISGIIGSYLYGINIKWPIYMT
                     GLFSILTILVILLTLVENVDCN"
BASE COUNT        31204 a        12607 c        15500 g        28152 t
ORIGIN      
        1 ataaaataat gctttacttc tatatttaaa agtgtataat gaaagttaag taataaagag
       61 cgtgaagaaa aatgtgagtt atttatatag aatattctcc ttttcattta tgaatttgtt
      121 acaaaatatt tagtgcaaaa gcacgacgga ggtattcaat atgaataacg gtacagttaa
      181 atggtttaat gcagaaaaag gttttggttt catcgaaaga gaagatggta gcgacgtatt
      241 cgtacacttc tcagcaatcg ctgaagatgg atacaaatca ttagaagaag gccaaaaagt
      301 tgaattcgac atcgttgaag gcgaccgtgg cgagcaagct gcaaacgtag ttaaaatgta
      361 attttaactt tttcaaacag tccttagtat agggctgttt ttttatgctt taaatcgata
      421 acagttggtg tggtaaaagc actagctgtt acttttttgt ccaataaata taggtggaga
      481 tctaacaata tataatggtt ctaaaataaa tcgaactgat ggaaaagttt tttacttttc
      541 atctgtccga cttttgattt tgaataaaaa aaagcgccaa tacagaactt taataatgac
      601 gagaattaaa gtctgtatat ggcgataaca agaagtaatg ttaaacactc aaaatgttta
      661 acaataatag gataccacat cgcataatat cttactactt aattaataat ttaactaatc
      721 aactttttgt taatttttta ttaagactga ttaattattg agaatattta ttgtttttaa
      781 aatctcataa taattcagta atcttgtttt catttaaaag gcggaacatt aaaataatta
      841 aataaaaata ttgcgtttaa tttacagcgt caaatatact tatttctaat gctttgaggt
      901 ctacagaaac aagtagagaa tgatcgatgt tattaacatt gccattctcc aaatctattt
      961 ctgtgagtat ttgaaagcta ccattaggca atggtttaac aatagacaat tgctcctccg
     1021 cttgttgtat taaaaaaggt tttgtagatt gattattaat atgccattca ctcatgtatg
     1081 tttttcactc ctgctttaat atagggttaa aaagtttata gttgagacat tcatgctcaa
     1141 ccaaaatttt gttcaaattc aataaatgtc ttgtttaaaa tagaaatatt gtaaatgtta
     1201 tcgtccaaaa cttcaccagt taagtatttg ttttgaatta aaatttggca gttagttaag
     1261 aagtcttgat aatcacgatc gcaaaaatag ttttcacgtg catctttagc atcgccaaaa
     1321 aagttagcga ctgtttctgt ttctccctta ttcgaacgtt caatatataa tttgtaaaat
     1381 ttagctattg tatacttttg ttctttagtt agttcattca aaatattggg cctcctgaat
     1441 tatcatttgt aatctatacc caatttattg caaaacacaa actaatttaa ctatttgatg
     1501 aaactgtgtt aataagcttt aacaagcctt agtttgtatg gatctataaa attatcttta
     1561 attgcatagg gtgaaataat atgtagtccg taacttttaa ctgatttttc acttacacca
     1621 aatttataag cttggtagat aattttagta caatacgtaa attttttgct gttcaaattt
     1681 aatgtaacta gataacgatg atttgtattt tcatagtttt tcttaaccca ttcagccgct
     1741 tttttacctg caccaggata gctgcaacga taaactttca tccaatcatt tttgccactt
     1801 gcataattat atttaaaaga ttcgaaggat tgtgtagttg gtttgtcgcc aggcccctca
     1861 atttgtaaaa tcgttttatc atcaatcgcg atactacaat gaccaaaaaa tccccacatg
     1921 acagggcctt ttgtaacaat aatatcacca ggttttaatt ggaatttgtc atcttgaatt
     1981 tctgaatact tattatctgc aattgttttt ggtgagttta taggggatac gacaacgaat
     2041 aatataagta aaattatcgt tcgtttaata tagttcactt aaaagctcct tgctgaagaa
     2101 atatatgtga atagtcttaa attagaattg taatctttaa taagcattta agactaaaac
     2161 atatcttaaa tattaaagta tgagagtgtg aaatgtctat taagaataaa aaacagtctg
     2221 aaacatcatt ggaacgtttc agactggata taaaatgatt ttcatttata gcacaccaaa
     2281 tataaatgtg tatattaata tagcgaatcc aaaaatatag agaatgacag taaaacttaa
     2341 ataggactct tttttagatt ctttgccagt ttttttcatt aatacgagta taaacgtagc
     2401 ggcaactaag aaaattaatg ctagccaaaa cagaattgca aaatgtaaag acatgtgaaa
     2461 ccctccttat ataccgtaat tattaaccta taaaactata aaaaatagga taaatgtaat
     2521 agagaacgag tacgatattt ataaaaaata atatttcact taaccagttt ttagttatca
     2581 ttgcaatggt aaaggatacg atgagtatca caccacaaat gataatacca ggcaggagcc
     2641 aacataaatc atctaaatct ttattatatg tgattaaaat attaaagata acaaaagtgg
     2701 tagtaataac tatattgata gcatttaaca aaatgttatt catgactgac acctactagt
     2761 ataaaaatag cttcttaata aatatgataa cactattttc caataggtaa ataaaaagta
     2821 tagttatttt taaaatatta ttgtagaatg ctaaagttta ttaattcaaa caagtgagca
     2881 tatatagagg tgtgtagtat taatatgaaa agaatattta caaactaaaa acctttaaaa
     2941 ttgtataatt cgttaatatt tttagaatca gataacaaaa aaatgtgcaa aatcactttt
     3001 gcacatttac aaatactagt tttctgataa gattaataat aacactttaa atagcgctta
     3061 ataaatgaag ggggtaagtc ttatgacgtt ttacaatttc atcatgggtt ttcaaaatga
     3121 taacacacca tttggcatat tggccgaaca cgttagtgaa gataaagcat tccctcgatt
     3181 agaagaaaga caccaagtaa ttagagcata tgtgatgtct aattacacag atcatcaatt
     3241 aattgaaact acaaatagag ctattagctt atatatggca aattaatttg agtagtacca
     3301 attatgatgt attagtgcat cccaaatatc ttttgtttta aagtttattt catcatttct
     3361 tatcgaaaat ggtgtaataa tgtctttatc taaccaagtg ttgataagtt catttggtac
     3421 accatctaac aacatttcac ttttactaat tataaaacat tcccagtcaa gtgaaacatt
     3481 ttgtggattc acataattac attgattatg attatccata aacactcact cctttaaaat
     3541 tctgtactct tcattgcgtt ttaccccgtc acattatctt ttaaactaaa atcatcatta
     3601 cttatgaaaa aaatgttcat caaaagcaaa ggtttttgct accgaaaaag tttaaataat
     3661 ggtttaatat atttggtact cattttaata aaaagagaat acattttgag ctatcaatac
     3721 tttttattga agaggtgtta ttgttggcta aaacgttata tttaatgcgc cacggacaaa
     3781 ctttgtttaa ttttaaggga ctaattcagg gatttggaga ttcgccgcta acagaacttg
     3841 gaattgctca agctcaaaag gcacgtagtt attatgaaac taaggggata aacttcgatt
     3901 tatatgcatc atcaacgcaa gaacgcgcaa gtgacacact tgaaaatgtt gcacctaacc
     3961 aatcgtatca acgttttaag ggactgaagg aatggcattt tggattattt gaaggtgagt
     4021 cagtctatct atttgataat ctatacaagc ctgaggactt attcggagat cgaattgttc
     4081 ctttcaaagg agaggcaagg caacaagttg aagatcgcat tgtgaaaact ttacatgaca
     4141 ttatgtctca aacaaagaat aatgcattag tcgtgagtca tggaacaata atgggagtat
     4201 ttttaagata ttgccttaaa ctagatgaag cattaaagca taatatcggt aattgtaata
     4261 tcctgaaatt tgaatatgac aatggaacat ttaaatttgt tgagttaatt gatccaaatt
     4321 tataataaat aaagcgttat acatagacac aagtatgtct tttgtataac gcttttaaaa
     4381 tacaactata taacgcttta gaatattaat tgaataagtt tttgtaatat catcagagca
     4441 acaataataa ttattatgct tgatatttta ttgattattg ttaataattt tccggtttta
     4501 tcaattgatc caaccatttt tcctaaaatt gcgagtaaaa agaaccataa ccatgaaacg
     4561 ctaatacaag cgattgtaaa cgcaatttta ttgctgccac tatataatgc agcactacta
     4621 ccaattacac caattgtatc taaaatagca tgtggattga gtaatgaaac tgataaagca
     4681 aaacttactt gtgtcattgg agacataatt tgagcttctc catctgttga gggtttatca
     4741 tgccaaatgg tccaagccat atacatcaag aaaattaaac caactatata aataattgct
     4801 tgaagtacag gtaaagacat aataatgata gatactccta ccactgcaat aatgataagt
     4861 aagctgtctg acaacccggc tgtaattatt gcaggcaata catatctata ttttggttga
     4921 ttagctcctt ggttaaaaat aaatacattt tgtgcaccta aaggtaaaat tagaccaatc
     4981 gctaagataa atccatgaat aattgcggtt accattaagt tttgacaccc ctaaaacata
     5041 gaatattctg aaaaaactta ttgatatcat accaaaaaaa acaactactc aatagtagag
     5101 tagttgtatg aaaaatagaa cctatatgat ttgaatttat gagaaatgta gaatatataa
     5161 aactgtatta cttattaatc aaatcataaa aaagccaatg ttcatcgaaa taggtgtttc
     5221 cgattttaat tgcatttttc tcaaaaccaa gaatgtcgaa tcctagtgca ctatagaaaa
     5281 ctttagcacc tatgttgttt gacacaattg atgtaagtaa agattcgtaa ttgttctgcc
     5341 gtgcataatt aataatgaaa ttaatgagct cgctattaat cgatttatcg ttattagtaa
     5401 caaagttgta tttaattaat gatttatgtt cttttccaac gtatcgaatt tgttctaagg
     5461 cagctgttgc gataagtgtt tcgttttcat aacagccaaa tacaatacat ttcggtgaac
     5521 cttgatttaa aatgtcatgt attaaggtgt cagtcattgt ttgactataa tgtgaatctt
     5581 gagtgaattc ttcattgact gtcgaaacaa gtctcttata ctcattaaaa tcattattcg
     5641 ttaatgtttt aattttaatc attactgacc tccttaatca ttattaagaa agattttgta
     5701 ctaaaaaaat ttcttaatta catattaaaa tgtttattaa aattttgcaa tcattgattt
     5761 atatgcacat tcttgtaaat ggattatcaa tttaattata tttattttta agttcaggaa
     5821 attatggaat tggttattgg tcgacactgg acttttattt gtagacggta tgcgaagaag
     5881 tcaagccagt attggaaccg gtcacattta tgatgactaa gggacaatca ttttcagtta
     5941 aatattgcca gaaatttcaa tcacgaatag aaaaaataac caaccaaaaa tttttggttg
     6001 gcaaatttga attttatgtg aattttatta ataacgttga ataatctctt taagttaatg
     6061 ctaatctaca acatttacat ttaaatcgac attaatattt ccttgagtcg cttttgaata
     6121 tggacaaaat tcatgagcca tttgtaaata tttttcagct tcttcttgag atataacatt
     6181 tttaattgtc gcatcaattg aaacacttaa tttaggactt tctgagtctg gatcatcttc
     6241 tagtctcact gttagtgtta cttctggatg agcatcacgc actttgtttt gctttaaaat
     6301 taggtcgaag gcaccgttga agcaagatgc ataacctgct gcaaataatt gttcggggtt
     6361 agtagcttta ccatctgctt gagcaggcgg aacgatatca atatctaatg ctcgatcatc
     6421 agtataaaca tgtcctttac gtccgccaac attcgtcgct ttagtttcat aatgtattgc
     6481 catacttata acctcctaat ttaaaataca tttatgcttt acccattcga aaatacctta
     6541 atcattttca tttatagcat tgtttgattg aaggataaaa agttgttgtt tacaataaaa
     6601 ataatgagta tctgaaatga gggatttact atgacacatg tggaagtagt agcgactatc
     6661 gcgccacaat tatctatcga agaaacttta attcaaaaaa ttaatcatcg tattgatgca
     6721 atagacgtat tagaattacg aattgatcaa attgaaaatg tcacagttga tcaagtggca
     6781 gaaatgatta caaagctgaa ggttatgcaa gattcattca aattattggt tacgtatcgt
     6841 acaaagttac aaggtggcta tgggcaattt acaaatgact tgtatcttaa tttaatatca
     6901 gacttagcaa atatcaatgg catagatatg attgatatag aatggcgaga agatattgac
     6961 attgaaaaac atcaaagaat cattacacat ttgcaacagt ataataaaga ggtggtcata
     7021 tcacatcata atttcgaaag tacgcctcca ttagatgaat tgcaatttat attttttaaa
     7081 atgcaaaaat tcaacccaga atacgttaaa ttagcagtaa tgccacataa taaaaatgat
     7141 gtgttaaatt tattgcaggc aatgtctaca ttttcagata ctatggactg caaagttgtt
     7201 ggtatttcaa tgtctaaact tggactaata agtagaacgg ctcaaggcgt ttttggtggt
     7261 gcgttgactt atggttgtat cggagaagca caagctccag gacagattga tgttactgat
     7321 ttaaaagcac aagtgacttt atactaataa aatgaattag gttgcttttg tgtaagtgct
     7381 gtcttataat tgagaagtat tatcattgtt cgtggaggag cgattttaga tggaattaca
     7441 acaagcaata gctaatagaa gaagtgtgaa aaaatttaaa agagatatgc acatagatga
     7501 cgcattgcta tatcaagcaa ttgagaaagc tgctgatgct ccaaatcacg gaatgaggga
     7561 accatggaga gttgtgcatg ttccgaaaga cagattagga gatatgagta aggatatttc
     7621 taaatttgca tttcctaatg aattagataa gcaacaatgt cattatgatg cagtaacgaa
     7681 acttggtggc atgttattgc ttattttaaa aacagatcca agacaacgtc aaaatgatga
     7741 aaactacttt gcatttggtg catatgcaca aaatcttatg ttgttacttt atgaagcggg
     7801 aataggtaca tgttggaaat cgccattata tatctatgat cctaaagtaa gaaaaacact
     7861 tggtataaag aaagatgaag ttcttgctgg attcttatat ttaacggatt tagaagaaga
     7921 tatgcctaaa gcaccacgta aaaatagaaa cttaattaca ttatattaat atgtataatt
     7981 atagaaacat taataaaagc tgagtcatga attgatggac atctatcgag ttagagattt
     8041 aatctaactt actagagtcg gtacaatcac agtctcagct ttttattgtg cagtatatac
     8101 acatttttat tttagtattt atttaaaagt ttctgctaaa aatgattcaa cttgttcagg
     8161 tgacttagca tttgctgaat gaaggtgtgc aattttgtcg ccgtttttaa atactagcaa
     8221 gctagggata cccataactt cattttcaac aactacatct tctaattcat cacgattaac
     8281 agtataccat tggtaatcat tatattgttc tacgattggg tcaatccata aatccatagc
     8341 acgacagtct gggcaccatc ctgcctcaaa tttaacaatt acaggtgtat cgctattaat
     8401 tacagattta aatgattcat tacttttgat tgcttgcatt gtaacaactc ctctagatag
     8461 tttaataatt tttattatag ctaaatttat aacataataa aaaattttag cttcaaaatg
     8521 aaagcctttt gctatggaaa atgatatatt tattttaaat acataaagga ggttgcagtc
     8581 gtatgattaa attttaccaa tataagaatt gtacaacttg taaaaaggca gcaaagtttt
     8641 tagatgaata tggcgtaagt tatgaaccaa ttgatatcgt tcaacataca cctacaataa
     8701 atgaatttaa aacaataatt gcaaatacag gcgtagaaat taataaattg tttaatacac
     8761 acggcgcgaa atatcgtgag cttgatttga aaaataaatt acaaacctta tcagaagatg
     8821 aaaagttaga gttgttatca tctgatggta tgttagtaaa gcgtcctcta gcagtaatgg
     8881 gcgataagat aacattagga tttaaagaag atcaatataa agagacttgg ttagcgtaag
     8941 tgaaatgtaa acgtttacta aatatctcga tatttagatt cattacatgt aaaatgaaat
     9001 aagctataca attgttaatt tttataaata tagttgaata gcatctagcc ttatggcatc
     9061 attaatgatg taaagattaa ttaggagggg attctcttgg cagtaccaaa tgaattgaaa
     9121 tattcaaaag agcatgaatg ggttaaagtt gaaggtaatg tagcaacaat tggaatcaca
     9181 gaatacgcac aaagcgagtt aggtgatatt gttttcgttg aattaccgga aacagatgat
     9241 gaaattaatg aaggggatac gtttggtagc gtagaatcag ttaaaactgt atcagaatta
     9301 tatgcaccaa tctctggtaa agtagttgaa gtcaacgaag aactagaaga tagtcccgaa
     9361 tttgtaaatg aatctccata cgaaaaagca tggatggtaa aagtagaaat tagtgatgga
     9421 agtcagcttg aagctttatt aacagctgaa aaatattcag aaatgattgg tgaataatca
     9481 ccgtgtaact ccttaatcta agattgagga gtttattttt agtctgagta agtaaataat
     9541 atgaaagaaa atttattagg tactattatt tggagtattg ctacatttta ttattcaaga
     9601 atgatgaaaa taatgaattt agctatttta aaaataaaaa ttgggggaag ttaatatgct
     9661 aaacattcaa gacgttagtc atctttctaa aaaggagcaa aaagcatata accgtttcgt
     9721 agaatctgta gaaaacggta atttaccagt actaccatgt attgaaatgg atctaaaaga
     9781 gatgaaagaa gaaacattaa accagagtaa gattggtgga atgccatttt taaaatcttt
     9841 taaagatata ccattagatg aaaataatgt accaatggta ttgttagcgc agattaattt
     9901 ggatgatctt ccagaacaac aagaattatt tcctgtaaaa gaagggatat tgcagttttg
     9961 gattagttca gaagatcaaa tgtatggaat gtctgaaaat ttaaagggaa acaatataaa
    10021 ctcaaggctt gtttatataa aagagccaat tacagattta tcactcgaaa atattcaagc
    10081 gcatttgaag tcattagatg ctgataatga ggatatcccg ttcagtggag cattttctat
    10141 agaatttaga ttgtcgaaac aaactattac atgtactgat tataagtacg atgaggacgt
    10201 gcttgcattg tggaataaag tcaatccatc cttcgcgcta aaatcaatgt ttggtggtta
    10261 tgatgaattg atggaacctg tgtgtaacac atttactgct aaggaaccat ttaatcaact
    10321 tggtggttat ccatattttg accaaataga tccaagaacg aacgatcaag aactgaaaat
    10381 gtatgataga gtcttactgc aaattgattc tacaagagat ggtaattctt cgattatatg
    10441 gggtgattta ggtattgcca atatcttagt gaaatctact gaccttgagg ctatgaagtt
    10501 tgatgattac atgtattcat gggattgcag ctaagagaat catgaaaata tattacttta
    10561 ataagtgtag tatctataga tcaatctagg gagtgggaca gaaatgaaaa agaaccacta
    10621 gtgatttata atgtagtggt tctttttcat aagccacagc taatgtgtac ttaaaaatag
    10681 gaatacatga gtaaaactca tgcataagaa atactaattt ctaaagaaaa agtatttctt
    10741 tatgttgggg ccccgctata attgaaaagt ttgttatagg tgtattttct tttggttaac
    10801 tattggtaat ataacattgt agattttagg atgttgattt ttgacttagc ctttgtctgc
    10861 ttatgttaaa tgtcccagct agtcaaacat tgattttgta attattatat taagctagtt
    10921 taaatttttt gtgatttatg ttttattcat accaattttg tgaaatgata cagtgacaga
    10981 tgtttattga ttttaaaggg tgatgatgat ggctattgta aataaagtga taattgttga
    11041 aggaaaatct gataaaaaaa gggtgcaaca ggttattgca gaaccagtca atattatttg
    11101 tactcatgga acaatgagta tagataagct tgatgatatg atagaatcac tgtatgataa
    11161 acaagttttt gtattagccg attctgatga cgaaggagat cgaattagaa attggtttaa
    11221 acgttatttg agtgaaagtg aacatatatt tattgataaa acttactgtc aagttgcgaa
    11281 ttgccccaaa caatatttgg cgcatgtact ttcaaaacat ggctttactt gtaagaaaga
    11341 aacacctctt ttaccgaata taaataatga aaggttagtt ttagtaaatg aataattcat
    11401 tagacatcaa agatgtaact acattttatg aggaagacaa acatttaatc tttggttata
    11461 caccaacgtg tggtacttgt aaggtttcag aaagaatgtt agacattgct aatgaaatat
    11521 tgcagttgcc attattgaaa atagatttaa acttttatcc tcagttttgt aaagatatgc
    11581 aaatcatgtc tacgccgatt ttattgttga tgaataaaga taaagaagta aaacgaattt
    11641 atgcatttaa atcggtgact gatttgttag aaaatttaaa atagttattg acgaaatttt
    11701 actaaggtgt taggattaat acaaattaaa tgatgcgtaa actcttatcg agagtggtgg
    11761 agggatgtgc cctacgaagc ccggcaaccg tcttatatag aaatggtgcc aattcacata
    11821 aagttttaac ttttgaagat gagagaaaca atactactat tgctttctca atttttctat
    11881 cgatattgag aaagcatttt tttattttat taagcaacac agggaggaat caacgtgatt
    11941 gaattaaaag aagttgttaa agaatatcgg actaaaaata aagaagtcct tgctgtagat
    12001 cacgttaatt tatcgattcg agcaggatcg atttatggcg tcattggttt ttctggagca
    12061 ggaaaaagta ctttgattcg aatgtttaat catttagaag cgcctacatc aggtgaagtt
    12121 attatagatg gggaccatat aggtcaattg tccaaaaatg gattaagagc aaaaagacaa
    12181 aaagtaagta tgatcttcca acattttaat ttattatggt caaggactgt gttaaaaaat
    12241 attatgtttc cgcttgaaat tgcaggtgtc cctagaagga gagctaagca aaaagcatta
    12301 gaacttgtcg aacttgtcgg tttaaaaggt agagaaaaag cttatccatc agagttatca
    12361 ggtggacaaa agcaacgtgt tgggattgca cgagcgttag ctaatgatcc aacggtcttg
    12421 ctttgtgatg aggcaacaag tgcacttgat ccgcaaacaa cagatgaaat tttagatcta
    12481 ctactaaaaa ttagagaaca acaaaattta acaattgtac taattacgca tgaaatgcat
    12541 gtcattcgtc gtatttgtga tgaagttgca gttatggaaa gtggtaaagt gatagaacaa
    12601 ggaccggtga cacaggtttt tgaaaatccg caacacactg tgacaaaacg atttgtgaaa
    12661 gacgatttaa atgatgattt cgaaacatct ttaacagaat tagagccatt agaaaaagat
    12721 gcttatatcg ttagattagt tttcgctggt tcaacaacaa ccgagcctat tgtatcgagc
    12781 ctatcaactg cctatgatat taaaattaat attttagaag caaatattaa aaatacaaaa
    12841 aatggaacag tcggcttttt agttctgcat attccatata tttcaagtgt agatttcgga
    12901 aaattcgaaa aagagttaat tgagcgacaa gttaaaatgg aggtgttaag acatgggtaa
    12961 atcatttagt gaaattataa atgaaatgat tacaatgcct aatattcagt ggccagaagt
    13021 ttggactgca atagtcgaaa cactatacat gacagtcgtc tcaactatat ttgcatttat
    13081 acttggtctt attttaggtg tgttattatt cttgtctgct aaaggtaagt ctatcggtgc
    13141 aaggttattt tattctatcg tttctttcat tgttaactta tttagagcga taccatttat
    13201 tattttaatt ttattattaa ttccatttac aagtttgata cttggaacga taagtggtcc
    13261 gacaggtgcg ttaccagcct tgatcattgg cgcagcaccg ttttatgcaa ggctcgtaga
    13321 aattgctttt aaagaaattg ataaaggtgt catcgaagcg gcttggtcaa tgggtgctaa
    13381 tacttggaca gtaattcgta aagtcctttt acctgaagcc atgccagcgc tagtgtctgg
    13441 cattacagtt acagcaatcg ctttagttgg ttcaacagca gttgcaggtg taattggtgc
    13501 cggtggttta ggaaatttag catacttaac aggtttcact cgaaatcaaa atgatgtcat
    13561 tttagtatca acagttttta ttttaattat tgtatttata atccaattca ttggggattg
    13621 gcttacaaat aaacttgata aacgataaat tgggggtttc attttatgaa aaaattattt
    13681 ggtcttattt tagtattaac atttgcagtt gtattagcag cttgcggtaa tggaaacaaa
    13741 agtggcagtg acgacaagaa aataacagta ggtgcttcac cagcaccaca tgctgaaatt
    13801 ttagaaaaag caaaaccatt attagagaaa aaaggttatg aactagatat taaaacaatt
    13861 aacgattaca ctacgcctaa taaattacta gacaaaggtg aaattgacgc aaactatttc
    13921 caacatacac catatttaaa cacagagaaa aaggataaag gttacaaaat cgtaagtgcc
    13981 ggtgatgttc acttagaacc tatggctgta tactctaaaa agtataaaag tttaaaagaa
    14041 ttaccaaaag gtgcaacagt ttatgtgtct aataatccag ctgaacaagg acgcttctta
    14101 aaattcttcg ttgatgcagg tttaattaag atcaaaaaag gcgtaaaaat tgaagatgct
    14161 aagtttagtg atattacaga gaataaaaaa gatattaagt ttaataataa acaatcagca
    14221 gaattcttac ctaaaatata tcaaaatgaa gacgcggatg ctgttatcat taattcaaac
    14281 tttgcaatcg aacaaaaact aaatcctaaa aaagattcta ttgctgtaga aagtgcgaaa
    14341 gataatcctt atgcaaactt aattgctgtt aaagaaggaa atcaagatga taagaaaatc
    14401 aaagcattaa ttgaagtatt acaatctaaa gatattcaag acttcattaa tgaaaaatac
    14461 aatggtgcag ttattcctgc taaataatta ttaatggctc agtaacgtga tgttgctggg
    14521 ctttttaatt taaacaggta tttatatgat atttaggaat gagatgctat tacggataaa
    14581 gtaaaatcct atatgcatgc gttctactca tttattccta tttttaattt cacatggata
    14641 gtgactacta catcataaat cattagtgat tctttatcat ttctgtccca ctccctcaag
    14701 ttaatgatga atctatttcg ctagttataa aatgatgtca aatcaataac aaaaattatt
    14761 taagtaaaat gtttagataa tttttcagtg ggtaagtatt atatataaca tttaattatt
    14821 ccgaggaggc atttattatg gcagacgaaa gtaaattcga acaagcaaaa ggtaatgtta
    14881 aagaaacagt aggtaatgtt actgataata aaaatttaga aaacgaaggt aaagaagata
    14941 aagcttctgg taaagcgaaa gaattcgttg aaaatgcaaa agaaaaagca actgatttta
    15001 ttgataaagt aaaaggtaac aaaggcgagt aattttactt ttttattcct aatacactgc
    15061 acatgccact tagtcggtat aaccatcggc taggtggttt ttgtattaaa aaagtggata
    15121 ccaaaattta ttaataatta ttttaatgtt agaaaaaaac taaataaaaa ctcgctaatg
    15181 atatccaata atatgtatac aaaacgagac atatattgca tatgattaac gagatactga
    15241 aaatatttta tcacccctaa aatgactatt cattttcagc ggtaattcga cctaaagtca
    15301 aacttacaat aaaaccgatg ataaatacta ctaatgaaac aaaccacatc acgatattag
    15361 ttggtaaacc tggaaatact gcaaagaggg agccaacaac aaaaccaatg attaatgcaa
    15421 aagtcattag tttatgatgt gttaggaaat actggataat tttgcttgaa ataatgaatc
    15481 cagcaagcac gccaaatccg actgcaagta atataggaag acctgtaaag ttaagtttaa
    15541 caacttcaga tattgctagc atgactatgc catagacgcc aaatactaat aacataaatg
    15601 aacctgaaat acctgggagt aacatagcac tagatgcaca catacctgca ataaagtatt
    15661 taataataag accagttgat agagtaagtg tttctccagc atgtttatcg ccattattca
    15721 ttaatgtaat aacaattaag atagcgatac cagctataac catcatgtaa tgtttagttg
    15781 taaatgacgt tttatagtta gaaattttca ataaatatgg aacgatacca atgattaatc
    15841 caccaaagaa aaacatagtt ggaatatggt gttggcttaa taaataatta aaaagattac
    15901 ttagtgatcc cattgccagt aacattccaa ttataatggg gattaaaaat gtaaaacttg
    15961 gccaaaaacg tcgtgagaat atgccgctaa ttgaagcgat aaattgattg tatataccta
    16021 acaataatgc aatagtccca ccgctaacac caggcaccaa gtcactcgtt cccatagcaa
    16081 aaccttttag aatattaatc catttaaatt gttgcatgaa taactccttt caaacgattg
    16141 gaataaaatc ataaatagca tcataccata ttacaaatgt cctagtgaaa tgataacata
    16201 ttttaaattc ataaaatcca ttgagaaatt atgtgcactt attatcattt atatttttaa
    16261 agagagcgga ttagagttgt actttagagt tattaaaaat aataaaaagg gtttaagttg
    16321 tttatattaa ggtataagta agttataatt aactgaacgc attattacaa agtctttttg
    16381 actacaaatt aaaattatta taaactagtt aagaaaactt tatattttac ggagggaata
    16441 taaaatggca tcaacattag aaatcaaaga cctacatgtg tctattgagg ataaagaaat
    16501 cttaaaaggt gttaacttga caattaacac tgatgaaata catgcgatta tgggaccaaa
    16561 cgggacaggt aaatcaactt tatcatctgc aattatggga cacccaagct atgaagtaac
    16621 taaaggagaa gtacttttag acggtgtaaa tattttagaa ttagaagttg atgaaagagc
    16681 aaaagcagga ttattcttgg caatgcaata tccatcagaa attacaggtg ttacaaatgc
    16741 tgatttcatg cgttcagcaa tcaatgcgaa acgtgaagaa ggacaagaaa tcaacttaat
    16801 gcaatttatt aagaaattag ataaaaatat ggattttcta gacatagata aagacatggc
    16861 acaacgttat ttaaatgaag gtttctcagg tggagagaag aaacgtaacg aaatcttaca
    16921 attaatgatg ttagaaccta agtttgcaat cttagatgaa atcgattcag ggttagacat
    16981 cgatgcatta aaagttgtat ctaaaggtat taaccaaatg cgtggggaaa actttggtgc
    17041 attaatgatt acacactatc aacgattatt aaattacatt actcctgata aagtacatgt
    17101 aatgtatgct ggtaaagtcg ttaaatctgg tggtccagaa ttagcaaaac gtcttgaaga
    17161 agaaggatat gaatgggtta aagaagagtt cggttcagct gaataatctt attaatacag
    17221 tatccatgag atgttcatct atatatgatg aaaatgaaca tttatacgaa atagtaaatt
    17281 tcatcaagta ggaggaaaaa gttatgacaa ctgatatttt gaacatttct gaagaacaac
    17341 ttgttgatta ttctaaagcc cacaatgaac cttcttggat gacagaatta cgtaaaaaag
    17401 ctttgaaatt aacagaaact ttagaaatgc caaaacctga taaaacaaaa ttaagaaaat
    17461 gggattttga ttcttttaaa caacacgatg taaaaggtga tgtttatcaa tctttatcac
    17521 aattacctga gtcagtaaga gaaattattg acgtagatca ttctaaaaac ttagtaattc
    17581 aacataataa tacgattgcg tacacacaag ttgatgataa tgcatcgaaa gatggcgtta
    17641 tcgttgaagg tttagcagac gctcttatga accatagtga tttagtacaa aagtacttta
    17701 tgaaagatgc agtaacagta gatgaacatc gtatcacagc gctacacacg gcattagtta
    17761 atggtggcgt atttgtttat gttcctaaaa atgtggttgt agaacatcca gtacaatacg
    17821 ttgtgttgca cgacgacgaa aatgcaagct tttataacca tgttatcatc gttactgaag
    17881 aaagcgccga agtcacatat gttgaaaatt acttatcaaa tgcatctggt gaaggaaatc
    17941 aattaaatat tatttctgaa gtgattgctg gcgcaaactc caatatcaca tatggctcag
    18001 tggactatat ggataaaggc tttacaggtc atatcattcg acgtggtatt actgaagcgg
    18061 atgcctcaat taattgggca ttaggtttaa tgaatgaggg tagccaaatt attgataata
    18121 caacaaattt atttggtgat cgttcaacaa gttcacttaa atcagtagtt gtaggtacag
    18181 gcgaacaaaa aattaatcta acatctaaaa tcgtacaata tggtaaagaa acagatggtt
    18241 atatccttaa gcatggtgtt atgaaagaac atgcatcatc tgtatttaat ggtatcggct
    18301 acattaagca tggtggaact aaatcaattg ctaatcagga atcacgtgta ttaatgttat
    18361 ctgaacatgc tcgtggtgac gcgaatccta ttttattaat tgatgaagat gatgtacaag
    18421 ctggtcatgc tgcatcagta ggtcgtgttg atccagatca actttactat ttaatgagtc
    18481 gtggtatttc tcaaagagaa gcggaacgtc ttgttataca tggtttctta gatccagtag
    18541 tacgtgaatt acctatcgaa gacgttaaac gtcaattgag agaagtaatt gaacgcaaag
    18601 tttctaaata atattttgaa aataaaagtt tgtaatagat atagactgtc gatattggta
    18661 taagactaat acaacgtcag tatttaaatg attaggattt ttatttaaga aaggtcgtga
    18721 atgaagtggc cgaacactca tttgacgtta atgaagtaat caaggatttt ccgatattag
    18781 atcaaaaagt caatggcaaa cgtttagcat atcttgattc aacagcgaca agtcaaacgc
    18841 ctgtgcaagt gttaaatgtt ttagaggatt actacaagcg ttataattca aacgttcatc
    18901 gtggtgttca tacattagga tcattggcaa ctgatggtta tgaaaatgcc cgtgaaaccg
    18961 ttcgtcgttt tattaatgcg aagtattttg aagaaatcat tttcacacgc ggaacaactg
    19021 cgtcgattaa ccttgtagca catagctatg gtgatgcaaa tgttgaagag ggcgatgaaa
    19081 ttgttgtcac tgaaatggaa catcatgcca atattgttcc ttggcaacag ttagcaaagc
    19141 gtaaaaatgc gacattgaaa tttataccaa tgacagctga cggtgaatta aacatcgaag
    19201 atattaagca aacgattaat gataaaacaa agatcgttgc tattgcacat atttctaatg
    19261 tactcggtac aattaatgat gttaaaacca ttgcagaaat agctcatcaa catggcgcaa
    19321 ttatcagtgt tgatggggcg caagcagcac cacatatgaa acttgatatg caagaaatga
    19381 atgctgattt ttatagtttt agtggtcata aaatgcttgg accaacaggt attggcgtat
    19441 tatttggtaa acgtgagtta ctacaaaaaa tggaaccgat tgagttcggt ggcgacatga
    19501 ttgattttgt aagtaagtat gatgcaacat gggctgattt acctactaaa tttgaggcgg
    19561 gtactccatt aattgcacaa gcaattgggc ttgcagaagc tattcgctat ttagaacgca
    19621 taggttttga tgcaattcat aaatatgaac aagaattaac gatatatgct tatgagcaaa
    19681 tgtctgcaat tgaaggaatt gaaatttatg gcccgccaaa ggatcgtcgt gcaggtgtaa
    19741 taacgtttaa tttacaagat gtacatccac acgatgttgc tacagccgta gatacagaag
    19801 gtgtagcggt tagagctggg catcattgtg cgcaaccgtt aatgaaatgg ttaaatgtgt
    19861 cttcaacagc tagagcgagt ttttatatat acaacacgaa agaagacatt gatcagttaa
    19921 taaatgcctt gaaacaaacg aaggagtttt tctcttatga attttaataa tctagatcaa
    19981 ttatatagat ctgtcattat ggatcattat aaaaatccta gaaataaagg tgtattagat
    20041 aacgggtcta tgacagtaga tatgaataac ccgacatgcg gtgaccgtat acgactaaca
    20101 tttgatatag aagacggcat tataaaagat gctaagtttg aaggtgaagg ttgttcgatt
    20161 tcaatggcaa gtgcatcgat gatgacacaa gctgttaaag gtcattcact tggagaagca
    20221 atgcaaatga gccaagaatt tacgaaaatg atgcttggtg aagactatgt gattacagaa
    20281 gaaatgggag atattgaagc attgcaaggt gtatctcaat tcccagctcg tattaaatgt
    20341 gccacattag cttggaaagc attggaaaaa ggtactgttg ctaaagaagg taaagcagaa
    20401 ggtacgactg aagaagaata gaatgctgtt aatcatagat gattttgata ttagacatat
    20461 aaaagtataa aaatttttat aagatgtcat gtcattgtta taatatggtt tacatcatga
    20521 attaaaaact tacgcacgcc gttgtaaata tatttttaag gagtgattga aatggctaaa
    20581 aaagcacctg atgttgggga ttataaatat ggattccacg acgatgatgt gtccattttc
    20641 agatcagaac gtggtttaac tgagaatatc gttagagaaa tttctaacat gaaaaatgag
    20701 ccggaatgga tgttagattt ccgtcttaaa tcattaaaat tgttttataa aatgccaatg
    20761 cctcaatggg gtggcgactt atcagaattg aatttcgatg acattactta ctatgtaaag
    20821 ccttcagaac aagctgaacg ttcatgggat gaagtgccag aagaaatcaa aagaactttc
    20881 gataaattag gaattcctga agctgaacaa aaatatttag ctggtgtttc tgctcaatat
    20941 gaatctgaag ttgtttacca taatatggaa aaagaacttg aagaaaaagg tattatcttt
    21001 aaagatacag atagtgcttt acaagaaaat gaagaattat tcaaaaaata ctttgcttct
    21061 gtagtacctg cagcagataa caaatttgcg gcgttaaact cagcggtatg gtcaggtggt
    21121 tcgttcattt atgtacctaa aaatatcaaa ctagatacgc cactacaagc ttatttccgt
    21181 attaactctg agaacatggg tcaatttgaa cgtacattaa tcattgctga tgaaggtgct
    21241 tctgtacatt acgtagaagg ttgtactgca ccagtttata caactagttc tttacactct
    21301 gctgttgtgg aaatcattgt gcataaagat gcgcacgttc gttatactac gattcaaaac
    21361 tgggcgaaca atgtatacaa tttagttaca aaacgtactt ttgtttatga aaacggaaat
    21421 atggaatggg tagatggtaa cttaggttct aagttaacga tgaaatatcc aaactgtgtt
    21481 cttttaggtg aaggtgcaaa aggtagtaca ttatctattg catttgctgg taaaggacaa
    21541 gttcaagatg ccggtgctaa aatgattcat aaagcgccaa atacatcttc aacgattgtt
    21601 tctaaatcta tttctaaaaa tggtggtaaa gttatttatc gtggtattgt acattttgga
    21661 cgtaaagcaa aaggcgctcg ttcaaatatt gaatgtgata cattaatctt agataacgaa
    21721 tcaacatcag atacaattcc atataacgaa gtattcaacg atcaaatatc attagaacat
    21781 gaagccaagg tttcaaaagt ttctgaagaa caattattct atctaatgag tcgtggtatt
    21841 tctgaagaag aagcgacaga aatgattgtt atgggattca tcgaaccatt tacaaaagaa
    21901 cttccaatgg aatacgcggt cgaaatgaac cgtttaatca agttcgaaat ggaaggtagt
    21961 attggctagc tttaaaccgc gttgttaagc tattcttaac ttccggaaat aggtattgat
    22021 accatttcga tactgaatat aacaaaaagc cacattaatg tggctttttt tggttttata
    22081 actaaatcgg attgatagat aagctttgtg cgtatttata aatccgattt tttgattggt
    22141 gtaaaaaata atcattgatg gtggataaag cgacaacaca aatacaacat gattgtggca
    22201 ttagagtgct ggtctttatt aaattaattg aaaactacat caaatattct ttaaagataa
    22261 ttcgatatta gttcgattaa gattcgttgt ataagtgagt taaaataaga aaactattaa
    22321 taatattaag ttcactacag atgttgctaa tggaccgtaa gttttaaaga catctttact
    22381 tttataacca acaatcgcat ctaaaaattg aactaaaatc attgcaatgg atatagttat
    22441 caaaaatata gcactatgaa tgactaaaga aaaaatagct aattaaaata aaggtaagct
    22501 tcgactaagt gcataatatg catttatatt atggctagat gcacatgctt gaattgaata
    22561 acctaaactt atactggcac taatgattgt aaatatagct aaaacaaaat acatgttaat
    22621 ccttctttct atatttggat ataaacaagt acttgtctaa agttatttaa aagataatta
    22681 gaataaattt atgagaaact tgttgttatc attatagcgg tttcaaatca ttataactat
    22741 gtcataaact gaatttgtta aaattttttt attgtgtaaa tttattcgta acaatcaggt
    22801 cgaactatag catcatttta ctaatgaacg cattaaagta actatgacta aaaatgcata
    22861 ttaattatca ttattaagac tattctatat aatgaatttt aactggttta ttaaacgaga
    22921 acgtcgggaa ttaagtaact acaataaaaa taagatatga caataaggag actacacgcg
    22981 tgatcattgc cataattata ttgatattta tttcgttttt cttttcagga agcgagacgg
    23041 cattaacggc tgccaataaa acaaaattta aaactgaagc tgataaaggt gataaaaaag
    23101 caaaaggcat tgtaaagtta cttgaaaaac caagcgagtt tattacaacg attctaattg
    23161 ggaataatgt cgcgaatatt ttattaccaa cacttgttac aattatggct ttacgttggg
    23221 ggattagcgt tggtattgca tcagctgttt taacagttgt tatcattttg atttccgaag
    23281 tgattcccaa gtctgtcgct gcaacatttc cagataaaat aacaaggctt gtatatccaa
    23341 ttattaatat ttgtgtcatt gtgtttcgcc ctatcacatt acttttaaat aagttgacgg
    23401 acagtattaa tcgaagttta tctaagggcc aacctcaaga acatcaattt tcaaaagaag
    23461 aatttaaaac aatgttagca attgctggac atgaaggtgc tttaaatgaa attgagacga
    23521 gtaggttgga aggtgtcatt aattttgaaa atttaaaagt aaaagatgta gatacaacac
    23581 ctagaattaa tgtgacggca tttgcttcaa atgcgacata cgaagaagtt tatgaaacgg
    23641 ttatgaataa gccatacact agatatccag tatatgaggg agatattgat aacattattg
    23701 gggtgtttca ttctaaatat ctgttggctt ggagtaataa aaaagaagat caaattacaa
    23761 actattcagc taagccatta tttgtgaatg aacacaataa agctgaatgg gtattacgta
    23821 agatgactat ttctagaaaa catttagcaa ttgtgttgga cgaatttggt ggtaccgaag
    23881 cgatagtgtc acatgaagac ttaattgaag aattattagg tatggaaatt gaagatgaga
    23941 tggataaaaa ggaaaaagaa aaactttctc aacagcaaat tcaatttcaa caacggaaaa
    24001 atcgcaacgt atctatataa ggagcgaaca gctatgtgga ataagaatcg acttactcaa
    24061 atgttaagta ttgaatatcc aattatacaa gcaggtatgg caggaagtac gacaccgaaa
    24121 ttagttgcat cagtaagtaa cagtggtggg ttaggcacaa taggcgcagg ttactttaat
    24181 acgcagcaat tagaagacga aatagattat gtacgccaat taacgtcaaa ttcttttggc
    24241 gtaaatgtct ttgtaccaag tcaacaatca tataccagta gtcaaattga aaatatgaat
    24301 gcatggttaa aaccttatcg acgcgcatta catttagaag agccggttgt aaaaattacc
    24361 gaagaacaac aatttaagtg tcatattgat acgataatta aaaagcaagt gactgtatgt
    24421 tgttttactt ttggaattcc aaatgaatct attataaaaa gattgaaaga agcaaacatt
    24481 aagctaatag gtacagcaac aagtgttgat gaagctattg cgaatgaaaa agcgggtatg
    24541 gatgctatcg ttgctcaagg tagtgaagca ggtggacatc gtggttcatt tttaaaacct
    24601 aaaaatcaat tacctatgat tggaacaata tctttagtgc cacaaattgt agatgtcgtt
    24661 tcaattccgg tcattgccgc tggtggaatt atggacggta gaggagtttt ggcaagtatt
    24721 gtcttaggtg cagaaggggt acaaatgggc accgcatttt taacatcaca agatagtaat
    24781 gcatcagaac tactgcgaga cgcaattata aatagtaaag aaacagatac agtcgttaca
    24841 aaagcgttta gtggaaagct tgcacgcggt atcaacaata agtttatcga agaaatgtcc
    24901 caatacgaag gcgacatccc agattatcca atacaaaatg agctaacaag tagcataaga
    24961 aaagccgcag caaacatcgg cgacaaagag ttaacacata tgtggagtgg acaaagcccg
    25021 cgactagcaa caacgcatcc cgccaacacc atcatgtcca atataatcaa tcaaattaat
    25081 caaatcatgc aatataaata atcgaccgca atccacaaaa gcacaagcac ccccaaacat
    25141 tattttagtg cttgccattt ttgtggattg cgtttctatt ttaccaatct aatcaaacga
    25201 aattatcgag ctgaaggtca ccgaaatgat tataattaaa cgaaattatc gagctaaagt
    25261 tcgctgaaat gattatgatt aaacgaaatc atcaaacgaa agttcactga aatgattatg
    25321 atcaaacgaa atcatcatac gaactgaaat gattataatc aaacgaaaac atcaagctga
    25381 agaacgccga aagattttaa tcaagcaaaa acatcaaacg aaagttcgct gaaatgatta
    25441 tgataaaagt tatatggtat gatgacattg gtgatatata tgataaacat cggattaaca
    25501 ggttggggtg atcactattc attatatgaa gatttagaac gccaaaccga taaacttaaa
    25561 acatatgctg gacattttcc ggttgtcgaa ttagatgcga catactatgc gatacaaccg
    25621 gaaagaaata tattgaaatg gataaaagaa acgcctgata catttgaatt tgtggtcaaa
    25681 attcatcaag cactcacatt gcatgcagac tacaaaacat ttgcagatac aaggcaagaa
    25741 ctatttgatc aatttaagaa tatgttagag cccttacata cacagaaaaa attagcaatg
    25801 gtattagttc aatttccgcc atggtttgac tgcaatgcac aaaatatcaa atatattttg
    25861 tatgtaagac agcaattaca agcatttcca atgtgtgtag aatttaggca tcaatcatgg
    25921 tttagtgatg catttaaaga acaaacattg gcatttttaa cagaacatca aatcattcat
    25981 gcagtagttg atgaaccaca agtgaaagat ggcagtgtac ctttagtcaa tcgaatcaca
    26041 aatgaaattg cgtttgtacg ttatcatgga cgtaatcatt acggttggac taagaaagat
    26101 atgtcagatc aagaatggcg agatgtacgc tatttatatg attataatga gcaagaatta
    26161 atagacttgg cacaaaaggc acaaatatta gcacaaaaag ctaagaaagt ttacgtcata
    26221 tttaacaata attctggtgg tcatgcagca aataatgcca aaacatatca gcgattattg
    26281 aatatagaat atgaagggtt agcaccacaa caattaaaat tattttaaga ggcgacgact
    26341 atgttattaa caattacatt attagtttta atcggaggtt tgtcagcgat tatagggtca
    26401 atcgtaggca ttggaggcgg tattattatc gttccaacaa tggtttacct cggtgttgaa
    26461 catggattac tacataatat tacaacacaa gtagcgatag ggacgtcttc agtcattcta
    26521 attgtgacag gactttcttc atcacttgga tatttaaaaa caaaacaagt tgatattaaa
    26581 aatggttcca tctttttatt tggattatta ccaggttcat tgcttgggtc attcattagt
    26641 agatatttaa catttgagtc atttaactta tattttggaa tctttttaat tttcgtagcc
    26701 attttattaa tggtaagaaa taagattaaa ccgtttaaaa tatttgataa acctaagtat
    26761 gaaaaaactt atgtagatgc taaaggtaaa acatatcatt atagtgtacc gcctttattc
    26821 gcttttgtta ctacattttt aattggtatt ttgacaggtt tatttggtat tggaggtggc
    26881 gcacttatga cgccactaat gcttattgta tttagatttc cacctcatgt agctgttgga
    26941 acaagtatga tgatgatttt cttttcaagt gtcatgagtt ctatagggca cattgctcaa
    27001 ggtcacgtag cttggggtta tgcaatcatt ttaattattt ctagttattt tggtgcgaaa
    27061 atcggtgtca aagtgaatca atcaattaag tcagatacgg tagtaacatt attgagaaca
    27121 gtaatgttgt taatgggtat atatttaatt attcgtgcgt tgatttaata caactttaaa
    27181 aggaggacgt caatttgagg cttacaattt atcatacgaa cgatattcat agtcatttac
    27241 atgaatacga acgcattaaa gcatatatgg cagaacatcg gccacgactt aaccatcctt
    27301 ctttatatgt tgatctaggt gatcatgtag atttatccgc acctataact gaagcaactt
    27361 taggtaaaaa gaatgtggca ttactaaatg aagcaaaatg tgatgttgca acaatcggta
    27421 ataatgaagg gatgaccatt tcacacgaag ctttaaatca cctttacgac gaagcaaaat
    27481 ttatagtgac atgtagcaat gttatagatg aatcaggtca tttaccaaat aatatcgttt
    27541 cttcttatat taaggatata gacggtgtga aaatactatt cgttgcagcg acagcacctt
    27601 ttaccccatt ttatcgtgcg ctagattgga ttgttaccga tccacttgaa tctataaaag
    27661 aagaaattga acttcaacga ggtaaatttg atgtattaat cgtgctaagt cattgtggca
    27721 ttttcttcga tgaaacatta tgccaagaat tgcctgaaat tgatgtcatt tttggtagtc
    27781 atacgcatca ttattttgaa catggtgaaa ttaataatgg tgtactgatg gcggcagctg
    27841 gaaagtatgg taattatctt ggagaggtta atttaacttt tgaggcacat aaagtagtac
    27901 ataaaactgc aaagattatt cctttagaaa cattacctga agttgaaact tcatttgaag
    27961 aagaaggaaa aacgttaatg tccaattcag taattcaaca tccagtagtg cttaagcgta
    28021 gtatgaatca cataactgaa gctgcatact tattagctca aagtgtttgt gagtatacac
    28081 atgcacaatg tgccatcatc aatgccggct tactcgttaa agatattgta aaagatgaag
    28141 tgacagaata tgacattcat caaatgttac cgcatccgat taatatggta agggttagac
    28201 tttctggtgt gaaattaaaa gagattatag ctaaaagtaa taaacaagaa tatatgtatg
    28261 aacatgcaca aggtttgggt ttcagaggga atatatttgg aggatatatt ctttataatt
    28321 tagggtacat tcattctaca gggcgttact atctgaatgg agaagaaatc gaagacgaca
    28381 aagaatatgt attaggtacg atagatatgt atacgttcgg tcgttatttc ccaatattga
    28441 aagaattacc aaaagagtat ttaatgccag agtttttaag agatatattt aaagaaaaat
    28501 tattggaata ttaaaaagta agattattgg attttcattt gtcatgaatt tcgatataat
    28561 gtttaaagat acacttaaca ggagggtatg tgttgttatg gcgacaaaaa acgaggaaat
    28621 attacgtaaa ccggattggt tgaaaataaa attaaatacc aacgaaaact atacaggact
    28681 taagaagatg atgagggaaa aaaatcttaa tactgtatgt gaagaagcta aatgtcctaa
    28741 tatacatgaa tgttggggtg cacgtcgtac agcgacattt atgattttag gtgccgtatg
    28801 tacaagagct tgtcgttttt gtgcggttaa gacaggttta cctaatgaac ttgatttaaa
    28861 tgagcctgaa cgtgtagctg aatcagttga attaatgaat ttgaaacacg ttgttatcac
    28921 tgctgttgcg cgtgatgatt taagagatgc tggttcaaat gtttatgctg agacagtacg
    28981 taaagttaga gaaagaaatc catttacaac gattgaaatt ttaccatcag atatgggcgg
    29041 ggactatgat gcgttagaaa cattaatggc gtcaagacct gacattttaa accataatat
    29101 tgaaactgtt cgtcgcttaa caccgagagt tcgtgcgcgt gcgacttacg acagaacatt
    29161 agagttttta cgtcgttcaa aagaattaca accggatatc ccaactaaat caagtattat
    29221 ggttggatta ggtgaaacta tagaagaaat ttatgaaacg atggatgatt tacgtgcgaa
    29281 tgatgtagat attttaacga ttggtcaata tttacaacct tcacgtaaac atttaaaggt
    29341 tcaaaaatat tacacgcctt tagagtttgg taaattaaga aaagtggcaa tggataaagg
    29401 ttttaaacat tgccaagctg gacctttagt acgtagttct tatcatgcgg atgagcaagt
    29461 aaatgaagct gctaaagaaa agcaacgcca aggtgaggca cagttaaata gttaatattt
    29521 aaccattaat aaggcataaa ggcttagttt gtacaaaacg aacgtgtcat agaagtaatc
    29581 attattttta tgaaacacta aaagtataaa ctgagccttt cattgtcata gataggtgaa
    29641 gaatttgata aaagtagatc aacattactt tgaattaata gaaaattatc gcgaatgttt
    29701 taatgaagaa caatttattg ctaggtattc agatatttta gataaatatg attacatagt
    29761 tggtgactat ggttacgatc aattacgatt aaaaggcttt tacaaagatt ctaataaaaa
    29821 agcagagatg agtaaacgtt tttcaaatat tcaagattac atatttgaat attgtaactt
    29881 tggttgtcct tactttgtat taagacattt gtctaaacaa gaggttaaaa agttaataga
    29941 agaagttcat ccgtctgatg tgatagatga cgacaataaa cttcaagatg tgaagattaa
    30001 gccaaccatt caagaaactg aacattaata aaacccttag ctagattgaa aatgggaatc
    30061 atgcaattca agcatggacc tgtaatctag ttaggggttt ttatctttaa tgaatgactt
    30121 catttaaata ctcagtaatt tcatcgcctt cttcagcatt tacacctaaa atatgagcga
    30181 tatagccttc ttcttttaaa tcatcagtac cgataatacc gaatttattt gtttgcatat
    30241 taagtacgag tgtcttacca taatgcctat ttgtatggac taacattaaa tcatatcgac
    30301 tatgctcgcc aacaaaacca acaaactgaa cttgactctc ttcgttgtca tcatataaat
    30361 acatatcaat cattttgtag cgactccttt taaaagtagt aaagttagta taacgacaaa
    30421 tgaagtatac tgcaaaatta tgataatata taagcgagag gtgacaagga atgtattttg
    30481 tagacaaaga taaactaact cagaaattag cctatttaca agcattaact gatgattacc
    30541 atgagagcaa gcacaatcat tatgcatttg aacgcattgc tcaaatgttg atagaatcat
    30601 cggtagatat agggaatatg attatcgatg catttatttt aagggatcct ggtaattata
    30661 aagatgtgat tgatatatta gaactagaaa atgttattac taaagaaaca cagcaggcga
    30721 ttaataaaac tgtcgatatt cgtaaacaat ttacatatga ttacacagcc ttagatatta
    30781 aggttatcat gccaatgttt gatgacgcat taccttatta caaacaattt attacagaag
    30841 taacgacatt tttacatcaa gaaaatgtac cagtaacagc ttttggtaaa ggagaaaatc
    30901 aataatgaaa cagtataaag cgtatttaat cgatttagat ggcacaatgt atatgggaac
    30961 agatgagatt gatggagcaa aacaattcat cgattattta aatgtaaaag gcattcctca
    31021 tttatacgta actaataatt caacgaaaac acctgagcaa gtaactgaaa aattacgtga
    31081 aatgcacatt gatgctaaac cagaagaggt tgtaacgtca gcgttagcca ctgctgatta
    31141 tatttcagaa caatcaccag gagcatcagt atatatgtta ggtggtagtg gtttaaatac
    31201 tgcgttaacc gaagcgggac ttgtcattaa aaatgacgag catgttgatt atgtagttat
    31261 tggacttgac gaacaagtta catatgaaaa gcttgcgatt gcaacgttag gtgtaagaaa
    31321 tggagcaaca tttatttcta caaatccaga tgtgtcaatt ccaaaagaac gaggattttt
    31381 acctgggaat ggtgctatta caagtgttgt aagtgtatcg acaggcgtat cgccacaatt
    31441 tattggtaaa ccagaaccaa tcattatggt taaagcatta gaaattttag gattagataa
    31501 atccgaagtt gctatggtag gcgatttgta cgataccgat attatgtctg gtattaacgt
    31561 aggtatggat acgattcatg tacaaacagg tgtatctacg ttagaagatg tgcaaaataa
    31621 aaatgtgcca ccaacgtatt cttttaaaga tttaaatgaa gcaatagctg aattagaaaa
    31681 atatatgtag tcattttata aagtaggtga attgatttgg taaaaatagt tgtttcgagg
    31741 aaaattccag ataaatttta tcaacaatta agtaaacttg gtgacgttgt tatgtggcaa
    31801 aaatcattag tgcctatgcc taaagatcaa tttgcgacag cacttcgtga cgcagatgct
    31861 tgttttatca cattaagtga acagatcgat acagaaattt tagcacaatc accaaattta
    31921 aaagtaattg cgaatatggc tgtaggatat gacaacatcg atgttgaaag tgcaacagcg
    31981 aataacgtgg ttgtcacgaa tacaccaaat gtacttactg aaacaactgc agaattagga
    32041 tttacattaa tgcttgctat agcacgccgt attgtagaag ctgaaaaata tgtagaagca
    32101 gatgcatggc aaagctgggg tccttattta ttgtcaggta aagatgtttt caattcaact
    32161 attggaatat atggtatggg agatattggt aaagcttttg caagaaggtt gcaagggttt
    32221 aatactaata ttctttatca taatcgatca agacataaag atgcagaggc ggactttaat
    32281 gcaacatatg tttcttttga aaagctgtta gcagaaagtg attttatcat ctgtacagcg
    32341 ccacttacaa aagaaacaca tcataaattt aatgctgaag catttgaaca aatgaaaaat
    32401 gatgcaattt ttattaatat cggtagaggg caaattgtag atgaaacagc attaatcgat
    32461 gcactagaca ataaagaaat tttagcatgt ggtttagatg tattagcaaa tgaaccgatt
    32521 gatcatacac atccattaat gggacgtgat aatgttctga ttacaccaca cattggtagt
    32581 gcatcagtaa caacacggga caatatgatt caattatgta ttaataatat agaagcggtt
    32641 atgacaaatc aggtaccaca tactccagta aattgaaaat aagtatggtt tttaatcatt
    32701 ggtaaaacaa gcaaagcaat tgttaaatat gttacgcttg acttgcgaat gtatatattt
    32761 gcgctgatga taattcaata acattataaa ctcgtcatat taatgtgatg agtttatttg
    32821 atttttgacg tatataacaa aattgttata tagactgtaa ttgtttattg tttaaataac
    32881 ctttaaaatg aatgatgttc tcaacatagt gtatcattta caataattga gtgatgacaa
    32941 ccaattacta tgttgaatct ataaaattaa aattgaattt cattatgaat atcgatataa
    33001 tgaattgtaa aaaacaaatt ttaaaacgta ttttatattg aacggtcttt ataaaggcgt
    33061 ttttactaag aactttaaga ggtgcaatat gaaatctaaa agtaaacagc cacctaataa
    33121 atatgttgaa gcattcaaac catatttatt aacactattg tatttggcaa tatttattac
    33181 tttatattta atttatggca gtggcgacac acacaataac ttcatttata atgagttcta
    33241 atgagggaga cttaatatga cagatattat taataagctg caagcgtttg cggatgcaaa
    33301 tccacaaagc attgctgtta gacacacaac tgatgaatta acttatcaac agttaatgga
    33361 tgagtctagt aaattagcac atcgattaca aggtagtaag aaaccgatga ttttattcgg
    33421 tcacatgtca ccatatatga ttgttgggat gataggtgcc attaaagcag gatgtggata
    33481 tgtacctgta gacacttcaa ttcctgaaga ccgtattaaa atgattatta acaaggttca
    33541 accagagttt gtatttaata cgactgatga atcatttgaa agtttagcag gcgaagtatt
    33601 tacaatagaa gatattaaaa catctcaaga cccagtaatt tttgatagtc agattaaaga
    33661 taacgacaca gtatacacaa tctttacatc tggttctact ggggaaccta aaggtgttca
    33721 aattgaatat gcaagtttag ttcaatttac tgagtggatg ttagaactta ataaatcagg
    33781 aaatgaacaa caatggctta accaagcgcc attttcattt gacttatctg taatggctat
    33841 ttatccatgt ttagcatcag gcggtacatt aaatcttgta gataaaaaca tgattaataa
    33901 acctaaatta ttaaatgaaa tgctaacagc aacaccgatt aacatttggg tatcaacacc
    33961 atcatttatg gaaatgtgtt tattattacc aacgcttaat gaagaacagt atagtagtct
    34021 taacgaattc ttcttctgtg gtgaaattct acctcacaga gcagcaaaag cgttagtaag
    34081 ccgtttccca agtgcgacga tttacaacac atatggtcca actgaagcta cggtagcagt
    34141 tacaagtatt caaattacac aagaaatctt agatcaatat ccgacattac ctgttggtgt
    34201 tgaaagacca ggcgcaaaat tatctactac agatgaaggt gaacttgtta tcgaaggtca
    34261 aagtgtaagt ttaggatact taaaaaatga ccaaaaaaca gctgaagtat ttaatttcga
    34321 tgacggtatt cgtacttatc acactggtga taaagcgaag tttgaaaatg gtcaatggtt
    34381 cattcaaggt cgtattgatt tccaaatcaa attgaatggc tacagaatgg aattagaaga
    34441 aattgaaaca caattacgcc agtctgagtt cgtaaaagaa gcgattgttg tacctgtata
    34501 taaaaatgat aaagttattc atttaattgg tgcaattgtg ccaacgactg aagttacgga
    34561 caattcagaa atgactaaaa atattaaaaa tgacttgaaa tcacgcttac cagagtatat
    34621 gattcctaga aagtttgaat ggatggaaca attaccattg acttcaaatg gtaaaattga
    34681 cagaaagaaa attgcagagg taattaacgg atgattccat atggtgattt tacattcttc
    34741 ttaattgctt taattgcatt attaccagtc attatacttg gatttttagg taagcgaagt
    34801 tacatttata atggcgtagt tacagcattt atgattgtgt taatcttttc ttctgataaa
    34861 cataatctgt ttgaccaaaa gtatttaagt gttcaattaa ttagttttat tatttacgtc
    34921 gtatggcaag ttttattgat aatgttttat tatcattcaa aaccaaaaaa taattcattt
    34981 tcaaaatttg taactgtaat ggttttatca atattgccat tagcacttgt gaaagtgtta
    35041 caaagtacat ggttaggtgg gcatcagatt cacttccatg aaagcaaatt aattgaattt
    35101 gttggtttct taggaatttc ttatgttaca ttcaaaagtg tgcagttaat tatggaaatt
    35161 cgtgatggtt ctatcaaaga aattaaagta tggaaattaa ttcaatttat ttcattcttc
    35221 ccaacgattt catctggacc aatcgaccgt tacaaacgtt tcgttaaaga cgataaaaaa
    35281 gtaccaacag gcaatgaata tcgtgaatta gtattaaaag caattcacat gattatgctt
    35341 ggtttcttgt ataaatatat tgttgcttac tttattaaca catatgcaat catgccgtta
    35401 caattagact tacatggttt tgtcaatttg tggttatata tgtacgcata cagcttatat
    35461 ttattctttg actttgcagg ttatagttta tttgcgatag catttagtta tttattcggt
    35521 attaaaacac caccaaactt cgataaacct ttcaaagcga aaaatattaa agatttctgg
    35581 aatagatggc atatgacatt atcattctgg ttcagagatt gtatttacat gagatcttta
    35641 ttctacatgt ctcgtaaaaa attattgaag agtcaatttg caatgtctaa cgtggcattc
    35701 ttaatcaact tcttcataat gggaatttgg catggtatcg aagtgtatta cattgtttat
    35761 ggtttatacc atgcagcatt gtttataggt tatggctatt atgaacgttg gcgcaagaaa
    35821 catccgccac gttggcaaaa tggtttcaca acagcactta gcattgtgat cacattccac
    35881 tttgtaacat ttggcttttt aatcttctca ggtaaactta tataataaag gagaatttaa
    35941 ttatggaatt tagagaacaa gtattaaatt tattagcaga agtagcagaa aacgatattg
    36001 taaaagaaaa tccagacgta gaaatttttg aagaaggtat tattgattct ttccaaacag
    36061 ttggattatt attagagatt caaaataaac ttgatatcga agtatctatt atggactttg
    36121 atagagatga gtgggcaaca ccaaataaaa tcgttgaagc attagaagag ttacgatgaa
    36181 attaaaacct tttttaccca ttttaattag tggagcggta ttcattgtat ttctattatt
    36241 acctgctagt tggtttacag gattagtaaa tgaaaagact gtagaagata atagaactac
    36301 attgacagat caagtactaa aaggcacact cattcaagat aagttatacg aatcaaacaa
    36361 gtattatcct atatacggct ctagtgaatt aggtaaagat gacccattta atcctgcaat
    36421 tgcattaaat aagcataacg ccaacaaaaa agcattctta ttaggtgctg gtggttctac
    36481 agacttaatt aacgcagttg aacttgcatc acagtatgat aaattaaaag gtaagaaatt
    36541 aacatttatt atttcaccac aatggtttac aaaccatggt ttaacgaatc aaaactttga
    36601 tgctcgtatg tctcaaactc aaattaatca aatgttccag cagaaaaaca tgtctactga
    36661 attaaaacgt cgttatgcac aacgtttatt acagtttcca catgtacaca ataaagaata
    36721 cttgaaatct tatgctaaaa accctaaaga aactaaagat agttatattt ctggttttaa
    36781 agagaatcaa ttgattaaaa tagaagcgat taaatcattg tttgcaatgg ataaatctcc
    36841 attagaacat gttaaacctg ctacaaaacc agacgcttct tgggatgaga tgaaacaaaa
    36901 agcagttgaa attggtaaag ctgatactac atcgaataaa tttggtatta gagatcaata
    36961 ctggaaatta attcaagaaa gtaagcgtaa agttagacgt gactacgaat tcaatgttaa
    37021 ttctccagaa ttccaagatt tagaattact tgtaaaaaca atgcgtgctg ctggtgcaga
    37081 tgttcaatat gtaagtattc catcaaacgg tgtatggtat gaccacatag gtatcgataa
    37141 agaacgtcgt caagcagtgt ataaaaaaat ccattctact gttgtagata atggtggtaa
    37201 aatttacgat atgactgata aagattatga aaaatatgtt atcagtgatg ccgtacacat
    37261 cggttggaaa ggttgggttt atatggatga gcaaattgcg aaacatatga aaggtgaacc
    37321 acaacctgaa gtagataaac ctaaaaatta aaatacaaat agcacataac tcaacgattt
    37381 tgattgagcg tatgtgctat ttttatattt taaatttcat agaatagtaa tatgcgcttg
    37441 gatatgtggc aataataaaa taattaatca gataaatagt ataaaataac tttcccatca
    37501 gtccaatttg acagcgaaaa aagacaggta ataactgatt ataaataatt cagtattcct
    37561 gtctttgttg ttattcataa tatgttctgt taatttaata tctttatatt agaatacttg
    37621 ttctacttct attacaccag gcacttcttc gtgtaatgca cgctcaatac cagctttaag
    37681 agtgattgta gaacttgggc atgtaccaca tgcaccatgt aattgtaatt taacaatacc
    37741 gtcttccacg tcaatcaatg agcagtcgcc accatcacgt aataaaaatg ggcgaagacg
    37801 ttcaataact tctgctactt gatcaaacat cgttgtatct tcagtaggca tcaggcaagt
    37861 ctcctttcga gagatgaatt tgataatctt tattagtata ttataataga tagtgtaata
    37921 aaaatctatc aaaccaatgg gggataaata tatggagcac gtgagtgtgg tagtatatgg
    37981 ggcagatgtt atatgtgcaa gttgcgttaa tgcgccaaca tcgaaagata tttatgactg
    38041 gctacagccg ctattaaaaa gaaaataccc aaatatatca tttaaatata cgtatataga
    38101 tattacaaaa gataatgaca acttaacaga tcatgattta caatttattg aaagaataga
    38161 acaagatgaa ctattttatc cattaattac aatgaacgat gaatatgtag cagatggtta
    38221 tatacaaaca aagcaaatca ctcgatttat agaccaaaag cttgtgaatg aataatatac
    38281 acataacaaa aagcaatgtc agtaatagtg tgaactgaca ttgcttttta attttaacca
    38341 ttatgatatt tatataacca aagtacgccg gattttaaaa tagaagcgag tcgtcctgtt
    38401 acagtgcgat ccatgatata tgcaaaacct tgtttatctc ctaatgaccc aacgatacct
    38461 tgtaccttta gttccggcat tttgtcaggt aatggttcat ttagccattg ctttttaagc
    38521 acatcggcaa tttgatcacc ttgaacttcg gctaactgag cacttggcgc atgtggtaaa
    38581 tcagcacaat caccaactac atagacgtta cgatatgttg gtacttgatg atactggtta
    38641 actatcacgc gtccattact atttatatca atcggcaagt tacgaacaac ttcaacaggt
    38701 tgaattcctg ctgtccatac aactaaatca atatctttag gttcatcaca gttatatatt
    38761 ttaccaggtt caactttatt aatatttgaa tttggaacaa cggtaacatt atttttggcg
    38821 aaccatttcg caacatactt acttaatttt tctggaaaat ttcttaaaat tcgcggccca
    38881 cggtcataaa gatatatttc caagtctgat ctactttctc ttaattcgct ggcaagttct
    38941 atgccgctta atccagcacc aacgatacca actttagcac cttctggtag ttcactaata
    39001 ctatggaaag tatcccgagc ctttgagagt gtttgaatac tatgtgtata ttcttcggct
    39061 cctggaacgt tatgatattt atcttcacat cctaaaccaa tgattagctc atcataatca
    39121 attttagagt taccgactga gacaatttga gcatctaaat ctatgtcgtt aatttcacca
    39181 taaactgtat tcacttgtgg atgattaggg aatttcatgc gaacatcttt atctgatttc
    39241 gtgcccgcag ctaaagcata aaattctggt ttcaatccat gaaatggcat acgatcaact
    39301 aatgtgactg tataatcttg tggtaaagaa gtagttaaaa tgcgtgacat gatacgcata
    39361 ttaccatatc cgccgcctaa caaaactaag tttttcataa tgaagtaccc cttttatatg
    39421 ttaatattta ctttaatttt gaaaagatca aagtgcatag atatatttgt taatgaacag
    39481 ttataaaatg caagtgtctt tgattcatca ataaccccta aaaaagtaaa tatgtattta
    39541 tatgcttatt atatattttt ttgaaaatga ctacaaataa atatttgtac taactaaggc
    39601 actattacat aactgggata agaaacatca gttgttgtaa ttgagcacat catgttaaaa
    39661 taccagtttt aaaatgctat aatattgtaa caaatgaaat aagaaggtga agtatgaatc
    39721 cgatcgtaga attttgtctc tctaacatgg caaaaggtgg agattatgtt tttaatcaac
    39781 tggaaaatga cccagatgtc gatgtgttag agtatggttg cctgacacat tgtggtatat
    39841 gttcagccgg gttgtatgct ttagtaaatg gtgatattgt tgaaggtgat tcgccggaag
    39901 aattattaca aaatatatat gcacatataa aagaaacttg gattttttaa ggaggagtta
    39961 tcatgccaac agttatatta acagaagcag ctgcttacga agtaaaagat atgcttaaag
    40021 caaatgaaat gccagatggc tatttaaaaa ttaaagtgaa tggtggcggg tgcactggtt
    40081 taacatacgg tatgggtgca gaagaagcgc ctggtgaaaa tgatgaaatc ttagaatact
    40141 ttggattaaa agttttagta gacaaaaaag atgcacccgt attaaatggt acgactattg
    40201 attttaagca atcattaatg ggtggcggtt tccaaatcga caatcctaat gcaattgctt
    40261 catgtggctg tggtagttca tttagaactg caaaagttgc aggtaatcct gaaaactgct
    40321 aataaaataa ctttttaatg gttaacccaa tttttgggat acaaattgat atcaattatg
    40381 attagggaca tatttgatta tgtcctattt ttgcgtaaag atattttgtt ttattaaaaa
    40441 gcttattgaa aattaagaat ctgactataa atagtatttt aaatgatcgt gataacggat
    40501 acatttttaa tcgaaatcag gctacgaaaa aattaattaa ttttttcaca atctgactga
    40561 atcttgcttg aaaatataac ataaaagcta tagaattagt attggattaa aaatgtcttt
    40621 tttgtgaaca tcacaggttt ttacataatt taaaagactt aaataacaaa atgatgataa
    40681 actagtatac attgtggtaa aagtagtaat gaccagttgt tactagtaat tatcagcatt
    40741 tggttaaaaa aatatgaaag cttaggtgaa attaaatggc tcaagatcgt aaaaaagtac
    40801 ttgtacttgg tgctggttat gcaggtttac aaactgtaac taaattgcaa aaagcgatat
    40861 caacagaaga agcagaaatt acgcttatta ataaaaatga atatcactat gaagcaacat
    40921 ggttacatga agcatcagca ggtacactaa actatgaaga tgtattatat cctgtggaaa
    40981 gtgtcttgaa gaaagacaaa gtgaactttg ttcaagcaga agtaacaaaa attgaccgtg
    41041 atgctaaaaa ggtagaaaca aatcaaggta tttatgactt tgatatttta gtagtagcat
    41101 taggtttcgt tagtgaaaca ttcggcatcg aaggtatgaa agatcatgct ttccaaattg
    41161 aaaatgttat cacagcacgt gaattatcac gtcatatcga agacaaattt gctaactatg
    41221 cagcatcaaa agaaaaagat gataacgatt tatctatctt agttggtggt gctggattca
    41281 ctggtgttga attcttaggt gaattaacag acagaattcc tgaattatgt agcaaatatg
    41341 gtgtggatca aaataaagtt aaaatcactt gtgttgaagc agcacctaaa atgttaccaa
    41401 tgttctcaga agaattagtt aaccacgcag ttagctactt agaagaccgc ggtgttgaat
    41461 ttaaaattgc tacaccaatc gttgcttgta acgaaaaagg ttttgtagtt gaagtagatg
    41521 gtgaaaaaca acaattaaat gcaggtactt cagtatgggc agctggtgta cgtggtagta
    41581 aattaatgga agaatcattt gaaggcgtta aacgtggacg tatcgttaca aagcaagatt
    41641 taacaatcaa tggttacgac aacatttttg ttattggtga ctgttcagcg tttatcccag
    41701 ctggagaaga acgtccatta ccaactacag cacaaattgc aatgcaacaa ggtgaaagtg
    41761 ttgctaaaaa cattaaacgc atcttaaacg gtgaatcaac tgaagaattc gaatacgttg
    41821 atcgtggaac tgtttgttct ttaggttcac atgacggtgt aggtatggta tttggtaaac
    41881 ctatcgctgg taaaaaagca gcattcatga aaaaagtgat tgatacacgt gcggtattca
    41941 aaatcggtgg tatcggttta gcattcaaaa aaggtaaatt ctaggcttta aataaagttt
    42001 cagctaaaca cataaaatta aattattcat ttataaagtc cttcagtgtc actgaagggc
    42061 tttattgttg tacaatttga agtgagtaac atatcaaatc taaggaggta cattatgaat
    42121 tttaaattaa ataacacact aagcaacgaa ataaatacat tgattattgg tataccagaa
    42181 catttaaatc agttagagcg cattagtttt aatcatatcg atattacaga atcacttgaa
    42241 agactaaaac atcaacatat tattggtagt aaagttggga agatttatac aactgcattt
    42301 gatgtacaag atcaaacata tcgtttaatt acagttggtt taggaaactt aaaagcacgt
    42361 agttatcaag atatgttgaa aatatgggga catcttttcc aatacataaa gtcagaacac
    42421 attgaagata cttatttact tatggattca tttatttcaa aatatgatca gttatcagat
    42481 gtattaatgg catgcggtat tcaaagtgag cgtgcaacat atgaattcga tcattataaa
    42541 tcaagtaaga aggcaccgtt taagacgaat ttaaacctta ttagtgaatc attaattgaa
    42601 ttagatttca ttcatgaggg tatcagtatt ggccaatcca ttaatttggc aagagacttt
    42661 agtaatatgc caccgaatgt attaacacca caaacatttg cagaagatat tgttaatcat
    42721 tttaaaaata caaaggtcaa agtagatgtt aaagattatg acactttagt ttctgaagga
    42781 ttcggacttt tacaagcagt aggtaaaggt agtaagcata aaccgagatt agtaaccatc
    42841 acatataatg gcaaagacaa agatgaagca ccaattgcct tagttggtaa aggtataacg
    42901 tatgattctg gtggttatag tattaaaacg aagaatggca tggctacaat gaagtttgac
    42961 atgtgtggcg ctgcgaatgt cgttggtatc attgaagcgg ctagtcgttt acaactgcct
    43021 gtaaatattg tcggagtgct tgcttgtgct gaaaatatga taaatgaagc atcaatgaag
    43081 ccagatgatg tatttacagc attaagtggt gaaactgtag aagtaatgaa tacagacgct
    43141 gaaggtagat tagtccttgc agatgctgtg tattatgcaa atcaatatca gcctagtgtg
    43201 attatggact ttgctacatt aacgggtgca gcaattgttg cactaggcga tgataaagct
    43261 gctgcatttg aatcgaatag taaagtgata ttaaacgata tattacaaat aagttctaaa
    43321 gtcgatgaaa tggtatttga attaccgatt actgcaaccg aacgtgcaag tattaaacac
    43381 agtgatatcg ctgatttagt taaccatacg aatggacaag gtaaagcgct atttgcggca
    43441 agttttgtaa cacattttag tggtcaaaca cctcacattc atttcgatat tgcaggtcca
    43501 gcaacgacta ataaagcttc atataatggt ccaaaagggc caacaggatt tatgattccg
    43561 acgatagtac aatggttaaa acaacaataa tttaattatt tgcctgatac aacttgtgtc
    43621 ttgatataca tttctaattt aactcttgaa agtataaagg atcgcattgt atcaggcatt
    43681 ttcattgttg taagaaaata taaatcgcat atccttgtga gcataaatca acttgactag
    43741 cattgcaaaa aaatattata agcatatgtt cattcagtca acgactacta atattacatt
    43801 ttagaactta gtattttgat tggtgttcca agcttgtaaa attgtttaat ttaatgaaag
    43861 ataaaattat tttaagaaag acaattaact aaaaaataaa gattattggt atagtttgct
    43921 attgacaggt gttaaagcta ctgatactat gtagtctata aacgctttag ttcgatagag
    43981 tgataaagga tggttgtcat atgataaatg cagtagtaat agcagtaatt ttaatgattg
    44041 tgctatgttt atgtcgatta aacgtagtta taagcttatt tatcagtgcg ctagttggtg
    44101 gcgtagtatc aggtatgagc attgaaaaag taattaatgt attcggaaaa aatatagtcg
    44161 atggtgctga ggtagcatta agctatgcct tattaggtgg atttgcagca ttaatttcat
    44221 acagtggtat cacagactat ttagtaggaa aaattataaa tgcaatacac gctgaaaata
    44281 gtcgatggtc aagagttaaa gtaaaagtga caataattat tgcattatta gctatgagta
    44341 tcatgagtca aaacttaatt cctgtacata ttgcattcat tccaattgtc atcccaccat
    44401 tgttaagtct gtttaatgac ttaaaaatag atagacgttt aatcggtttg attatcggtt
    44461 ttggtttatg tttcccgtat gtgttattac cttatggatt cggtcaaatt ttccagcaaa
    44521 ttattcaaag tggctttgca aaggcgaatc acccaattga gtttaatatg atttggaaag
    44581 caatgcttat tccttcaatg gggtatattg ttggcttact tatcggttta tatgtatatc
    44641 gtaaaccacg tgaatatgaa acacgtaaaa tttcagatag tgacaatgtt acagagttaa
    44701 aaccatatat cttaatagta acaattgtag caatactagc tacattttta gtacaaacat
    44761 ttacagattc aatgattttt ggtgcactgg ccggggtact cgtattcttt atttcacgtg
    44821 catataattg gtatgaatta gatgctaagt ttgttgaagg tattaaaatt atggcttata
    44881 ttggtgtagt tattttaaca gcaaatggat ttgctggtgt aatgaatgct actggtgata
    44941 tagatgaatt agttaaaact ttaacaagta ttactggtga taataaatta tttagcatta
    45001 tcgtgatgta tgtgataggt ttaattgtca ctttaggtat tggatcatca tttgcaacca
    45061 ttcctattat cgcatcatta ttcattcctt ttggagcgtc aattggacta gatacaatgg
    45121 cattaatcgc attgattgga acagcgagtg cattaggtga ctcaggttca cctgcaagtg
    45181 attcaacatt aggaccaact gcgggattaa atgttgatgg ccaacatgat catatacgcg
    45241 atacatgtgt accaaacttc ttgttttata atattccttt aatgattttc ggtactattg
    45301 ctgctatggt actataagca taaagaggtg aaaatatgac gcatttatta gagacatttg
    45361 agatgtcaat agatcaccag gaagatggtt tagttgttat ttctatgcct gttactgata
    45421 aagtaaaaca accatttgga tatttacatg gtggtgcttc gattgcttta ggtgaaacag
    45481 catgttcatt aggatctgct aatctaattg atacaaccaa atttattcca ttaggtttag
    45541 agatgaatgc caatcatatt cattctgcta aagatggtcg tgttactgcg acagctgaaa
    45601 ttattcatca aggtaagtcg acacatgtat gggatataaa aattaagaat gacaaagaac
    45661 aattaattac agttatgcgt ggtacagttg ctattaaacc tttaaaataa aagaactgct
    45721 agctgaaatg ttatgagata ttcataacta cggctagcag tttttttatg cgctatattg
    45781 ttgtagtttt agaaatgctt gttcaatgcg ttcggcagct ttacggccac ccataacatt
    45841 tctaccaaat ggtcctaatt ctaagtctgc aaagcatcct gcgacaaata gatttggtat
    45901 ccattctaat ttttcggaaa taacagggta attacattcg ttaataggtg catcataatt
    45961 ttgtattaat tgcttaataa gtggttgtga cataaaatct tgttcaaaac cagttgcaac
    46021 cataatctgt tgatatggaa cagaatcatt ttcagtgtta attaaaccat cactaatttg
    46081 agtgataggt gttttatgca catttatacg accattttta atatgttttt taaggcgtaa
    46141 gtacagttcg tgaggcattg atcctttatg acgttcacgt tgtacaatgg catttctttc
    46201 aggcatgctt ttagtactta aaaatgtaga catattcttc ggacctaacc aaccaggatc
    46261 agcatcaaag tcatgtattt caatatcttt atttagccat aaatgaatct ttttatcgtt
    46321 atcatgattt aacaatttaa gtgcaagatg tgcagccgta atgccactac caacgatatg
    46381 atcggtctta tcatatacta cttgatcatg ttctttctcg aagatatgat ttacattctg
    46441 tttgtctttt aaaatgtcag gcataaacgg aatatttgta ctacctattg caataacgac
    46501 gcaatctgta gtgataattt gtccatcttc taacttgata tgccatttgt cttcttgttt
    46561 atctaaagtt tgaactaaac cttgaactaa accttgaacc aagcaatcct ctaattgata
    46621 ttgtttagaa gcatgtgcaa tatgatccat aaacattgtc aattcaggtc gttgataagg
    46681 accataaaaa gcatttgtat attggtgctg tttagcgaat tgttttagat ggaacggttg
    46741 tggatgtacg tgatgtacaa tcggtgatct taaataaggc atttctattc gatttgtaaa
    46801 tgagttaaac ctttggcaaa aagtttcgtg tgggtcaatg attgttaatc ggtctgttgt
    46861 taatccgctt gataatagtt tttgtgcgat tgcagttccc tgtatgccac cgccgataat
    46921 tgtccaatgc ataataaaac ctctctcttt ttaaagcgta atcgttacga tttataatta
    46981 ttattatcat aatacataac gacatgaaag gcaattaaat taaagagata tatgtagata
    47041 gggcgaagct gtagtcaaag aaaaaaccat tgaaaaagag gtaacaatgt caaaagaaaa
    47101 cagcagtaaa atcattccta atttggaatc atcttactgc tgtttgttgt tgatttatat
    47161 tcatgatttt gttatataat ctacaatttt gtgtctttta agtcttccga aatttcatcg
    47221 actttagtct ttttagtata aggcgtttta atattatatg ctgctttcat aatcatatga
    47281 cttgaaagag gacctgtaat taatacaaag ataatcgcaa cgattaattg catatttaca
    47341 aaaccttgag tagcaataaa atataaaaac gtaccaaata gtaatgacat tgcacctaat
    47401 gttgatgctt ttccggcagc atgtgcacgt gaatatacat cttcaagtct caataatcct
    47461 atagctgcta gggcgctaat taaagcaccg atgataacaa agataagtgc aagactaatc
    47521 agtatgattt tgatcatgtt caatcacctt acctttgtcc ataaatttag agaatactgc
    47581 agtacctaaa aaagctaata taccaatcat cataataacg acaatcatgt atttaatatt
    47641 taataaaata ctgaataatg ctataactgc cattaattga agaccaatcg catctaatgc
    47701 gacaacacga tcggcaagtg atgggcctag cacaacgcga atgagcatag ctaacataga
    47761 aatgacaact atgattaatg caataacgat aataacatta tgattcatta tatttcgccc
    47821 acctctctta caattttctc taatgatgtt ttaatacttt ctacttcttg ctctttagtt
    47881 gaaaaatcta tggcatgaat ataaattttt gtacgatcgt cacttacacc aagcactaca
    47941 gtaccaggtg ttaatgtaat taaattagac agcaagacaa tttgccaatc tttttttaaa
    48001 tcggtgtgat aaacaaagaa tcctggttca tttttaatcg aaggtttaat aataattttc
    48061 aaaacatcaa aattagcttt aatcagttcg attaagaaaa taataactaa tttaataata
    48121 cgatatagcg tgatgacata aaatctacct ggtaacactc tgtgtaagag gtaaacaaga
    48181 actaggccaa agatgaaacc taacacaaag ttatttgttg tgtaactatt tgttacaaac
    48241 aaccaaaaca ctgcgataat aaagtttaat actaattgta cagccatgtt atttacctcc
    48301 taatacagct ttaacgtagg ttgatggatt gtagaatgtt tctgcaccag cttttaccat
    48361 tggatataag taatctgctg acaatccata taaaacagtt atcacaactg caacgattgc
    48421 aatcgtagtt aaatatttga cgtcgacttt gttattaaga tcatatcctt ttggttgacc
    48481 gaaaaagcct tgtaggaata tgcgaatgac agaatataat acgactaaac ttgataataa
    48541 gacgatgaca ccacttaaat aaaatcctct ttcaaatgtt gattggacaa tgaaaaattt
    48601 tccataaaag ccactgagtg ggggaatgcc agctaaactt aatgctgcga taaagaatga
    48661 ccaaccaagt acaggatatc gtttaattaa gccaccaaat tgtcttaaat cagcagtgcc
    48721 tgtaatttta atcataattc cgataagcaa gaataatgca agttttacta acatgtcgtg
    48781 caatgtatag taaatagccc caatcatacc tgactctgtc atcattgcaa cgccgactaa
    48841 gatcacacct acagcaatca tgacattgta taggatgatt tttttaatgt tggcatatgc
    48901 aacagcaccg acacaaccaa agatgatcgt taatagtgct aagaataaaa tgacataatg
    48961 tgaaaagctt acattatcac taaagaatag gcttaatgtt ctagcgattg cataaacacc
    49021 aacttttgtt aacaaagcac caaagaatgc aatgattgga attggtggtg catagtatgc
    49081 actaggtaac caaacaaaca ttggaaatac gccagctttt gtagcaaaaa caaagataaa
    49141 tagtatgaaa acgatattga ctaagccact gtcatgcgct gaaaggttag ctaatttatt
    49201 gcttatatct gctagattca atgttcctac tactgaatat aaaatcgcta cacccattac
    49261 gaagaaggat gacgatacaa cgttaacaag aacatatttt attgtttcct gtagttgaat
    49321 ttttgtagaa ccaattacta ataagaaata agatgacatt aaaaatactt cgaaaaatac
    49381 gaataggttg aaaatgtcac cagttgtgaa tgcaccaatg atacctatta acataaatag
    49441 tactgaaaaa taataataat atctttcacg ttcaatacca attgtttggt atgaatataa
    49501 aatcacaata gctgtaataa taatactagt aattattagt agggcactga atatgtctaa
    49561 tacaaagaca atactgtatg gtgctttcca tgaacctagc tctacgcgta ttggtccatg
    49621 tttaacaaca tttgctaaat tgataattgc cgcgaccaag gttaataatg taccgcctag
    49681 tgcgacataa cgctttataa taggacgctt tccaataaag acaagtaata tggctgtaat
    49741 tactggaata actagcgtta acacaagcat attactttca atcatcttct ggaactcctt
    49801 tcatactctc aacgttatct gtgcctaatt ctttatatgt tctaaatgct aatactaaga
    49861 aaaaggctgt tgtcgcaaag gcgataacga ttgctgttaa aataagtgct tgcgggatag
    49921 gatcaacata gctttttacg ttcgcttcat aaattggaac agtaccatgt ttaagtccgc
    49981 ccatagttat taaaaataaa tttgctgcat gtgttaatag tgtagttccc ataacaattc
    50041 gtatcagact tttagacaaa acgagataga cactaattgc tgtgagaata ccactaacaa
    50101 aaatcataat aatttccact attcgttctc tccaatcgaa ataataattg tcatgacagt
    50161 accaactact gcacataaaa caccgaaatc aaagaatact gctgttgtca tatgaacagg
    50221 ttctaatata aataacggta tatcaaatgt gacatgcgta aagaaatttt tgcctaaaaa
    50281 ccaacttgcg ataggcgtcg caatacaaaa aactaatccg atacctatca agattttaaa
    50341 atctaacggg aaaattttac gcattgtttc tatatcaaat gcaatcgtaa tgataacaag
    50401 tgaacttgcg aataataacc cgccgacgaa accgccacca ggtgtataat gtcctgctaa
    50461 gaaaagtgaa aaaccaaaga ccattaccat gaaaaagata ataactgcag caaattgcaa
    50521 aattagatca ttttgttgtc tattcatgat ttttcacctc gttaccttgc gtttgacgct
    50581 ttttacgtaa tttaatcatt gtatatacag ctaatcctgc gataccaagt acagatgact
    50641 cgaataaagt atccatacca cggaaatcaa caagtatgac gtttaccatg tttttaccgt
    50701 gagctaaatc ataaacgtgc tcttgataaa acttagatat cgattcaaaa tgtctatttc
    50761 cgtatgcaat taaaccgata ataatgacgg acaaaccaac tccaccagca attaaagcat
    50821 tagtaagctg gaatgagcgc ttttcattat aacgatttaa atttggtaag tggtagaagc
    50881 ataataagaa caatgctgtt gaaatagatt caacgacaaa ctgtgtcaat gctaagtcgg
    50941 gtgctttaaa gaatataaac aatacagaca cagcatatcc aactgcactt aacataataa
    51001 tgctaaataa tcttgattta gcgaaaagaa ttaaaaaggc agcacttaat aataaaatta
    51061 cgatacaaac ttcgaaaatt ctaatcggac taacgtcttt aaaattaatg ttgaaaggta
    51121 ctgagaatat agtgacaaat gttaataaaa ttaatgtacc aaaaatgata actaaattat
    51181 tacgtgaata atcggtaaca tagctattcg tcatcttttc agagtagttt ggaataacat
    51241 ttgcacttct gttgtaccaa taattgaatg ttagtttacc aggttgtcgt tgcaacaatt
    51301 tcacccaata actaaatgtc acaattagta agatacctaa aatataaatc actaatgttg
    51361 ataaaaaggc aggcgttaat ccatggaaca tatggaattc aacatcatca attaccgtat
    51421 gattaatcga agatgtagca ggttcaataa tcgaattagt taaaatgcca gggaataaac
    51481 cgaatacaat tactaatgta gctaaaatag ctggtgataa aagcattaat attgatactt
    51541 cgtgtgcttt tttaggtaat tgttcaggtt tatattgtcc gaaaaatata tgcattataa
    51601 atttatttga atatacaaat gtgaagacac tgcccactat accaatgatt gggaataggt
    51661 agcctaatgt atcaacactg aataaatttg cttggcttgc tgtaaatgtt gtttctaaaa
    51721 atgattcttt tgataagaaa ccattgaacg gtggtacacc agccatactt aatgctgtaa
    51781 taacagtgat tgtaaatgaa ataggcataa ttgttagtaa gccacctaat ttcttaacat
    51841 cacgtgtacc agtagaatga tccactgcac ctgtaatcat aaatagggca cctttaaatg
    51901 ttgcatggtt gattaaatgg aatattgcag ccgtaaatgc agcagcatat attttgctat
    51961 catcgccttg atagtgataa ctaatggcac cgattccaag catcgccata atcataccta
    52021 attgggatac tgttgaaaat gccagtatac ctttcaagtc ttgttgtttt gttgcgttta
    52081 gcgaagccca gaataacgta attaaaccaa cgagtgtgac agtccatatc caaccttgcg
    52141 atgctgcgaa gattggtgtc attcgagcga ttaaatataa ccctgcttta accattgttg
    52201 ctgaatgaag ataagcactc actggtgtag gtgcttccat tgcatctggt agccaaatat
    52261 aaaatggaaa ctgagcagat tttgtaaaag caccaatcat gattaaaatc atcgcaaaaa
    52321 tgaagaatgg gctattttga atttcagaag catgttgaat catgtactga atgctaaatg
    52381 attgtgttgg tatagcgagt aagatgatac cacctaataa tgatagacca ccaaatactg
    52441 tgattatgag cgatttttga gcaccatata tagatgcttg tcgttcgcgc cagaatgaaa
    52501 taagtaaaaa actagaaaat gacgttagct cccagaataa atatagaata ataacattat
    52561 ctgaaagtac gacacctaac attgcaccca taaatagtaa taaataacaa taaaaattcc
    52621 ctagttgttc tgacttactt aagtagccga ttgaatataa tactactaaa ctgccgattc
    52681 ctgaaataag caaactaaag agtaaaccta agccatcaag atataaatca aagttcatac
    52741 caaaatgagg catccaattt aaggttttca ttacagtatt acctgacatc gtcgttttaa
    52801 ttaatgtaag catataaata aatatgacga tagggacagg taatacgaac catcctaaat
    52861 gtatacgttt aaaaaatcta tacaggatag gaataatgag tgcgaatatt aacggtaata
    52921 tcaccgcaat atgtaacaaa ctcactatgt tgtcctcctt taaaaaatat ttatgttatt
    52981 cattatacat gaatgatata gttctgaaaa acgtacacac tccttgttgt gctttatttt
    53041 cagaagtatt taaataagaa gaaacacgtc attttttatt taaaattttc tttgtattga
    53101 agtgaataat cttcttttaa gcgtgctaaa ctagctaaag acatttcagc atgttttgtt
    53161 tgctgagctt taagtttagt ttctaaatct gtaattgctt gttgaagtga atcttcatag
    53221 cgcaatacat caacattgaa gtcgcgtaat tgtgaacgtt tcgtatagcg tttttcaaaa
    53281 tggcttaatg ctttgcgttc atggaaaaat acaccttcag tttcagtagg gttatgtaaa
    53341 tcaccttgtt tcgggtgttt gataacttgt tcaactttaa caaggacatc gtctccattt
    53401 tcttcaacaa tcgtgacacc atagctacct gttttgtgtg aaaatcgata taacttcatg
    53461 ctattttcct cccttaaaag tatgttaata tatatgtatc ataacatgaa tggagaatat
    53521 aaatggctaa ctatccacag ttaaacaaag aagtacaaca aggtgaaatt aaagtggtta
    53581 tgcacacaaa taaaggtgac atgacattca aattatttcc aaatattgca ccaaaaacag
    53641 ttgaaaattt tgtgacacat gcaaaaaatg gttattatga tggaataaca ttccaccgtg
    53701 tcattaatga cttcatgatt caaggtggcg atccaacagc tactggtatg ggtggcgaaa
    53761 gtatttatgg cggtgctttt gaagatgaat tttcattaaa tgcatttaac ttatatggcg
    53821 cattatcaat ggctaactca ggacctaata caaatggttc acaatttttc attgttcaaa
    53881 tgaaagaagt acctcaaaat atgttaagtc aacttgcaga tggtggttgg ccacaaccaa
    53941 tcgttgatgc atatggcgag aagggtggta caccatggtt agatcaaaaa catactgtat
    54001 tcggtcaaat cattgatggt gaaactacat tagaagatat tgcaaataca aaagtgggac
    54061 cacaagataa accacttcat gatgttgtaa ttgaatctat tgatgttgaa gaataaaatc
    54121 taaacataat taactaccaa cattttaaac tcggataaag ctaatttatg aatggattag
    54181 tatatattcc aacgaaaaca aataaactaa catgatgagc aatctcaata tatttatcaa
    54241 gaaagcacag tttttaaata gatgtgtatt ctaaagataa tagttgaggt tgctttttat
    54301 gtttttacag agaattgcta ttcaaatagt taataaattg aaaacaaagt agctggatat
    54361 catattgatt tagataggaa tttgttgctg attttatttg taaatccaag tttgtagtat
    54421 tcttattcat ttataaaata atattcgtat gatttgatgt tttaattagt ccaccatttc
    54481 gatttgtgct atgataatag tgttaagtaa acgaaataag gggttattaa gttgaataac
    54541 tacaaaattg gccaacatat caaggtgcgt gtaactggta ttcaaccata cggtgcgttt
    54601 gttgagaccc ctaatcatac tgaaggactg attcatatat cagaaattat ggatgactac
    54661 gttcataatt tgaagaaatt tctatcagaa ggccaaattg ttaaagctaa aattttgtct
    54721 atagatgatg aaggaaagct taatctatca ttaaaggata atgattactt caaaaattat
    54781 gagcgtaaga aggaaaaaca atcagtatta gatgaaatca gagaaacaga aaaatatggg
    54841 tttcaaacac ttaaagaacg cttaccaatc tggataaaac agtcaaagca agcaattcga
    54901 aacgactaaa ggaacagata aatcgtaccg aaaatcatac aaagggtctg aaatgaaagt
    54961 ttcttagact ataaaagaga ttagtatcta ttaaatttta ttagatacta atctcttttt
    55021 gtctacgata acgtaatatg attgattcta tttacacgta caaatggttt aaggtgacat
    55081 atccattatc tttgatagat agaatcgttg atttgcaata ttgtatgtgg atttgttttt
    55141 ttaatttatt ttagaaatga gaactacaac ttaaagtatt aaacgaattg caactatata
    55201 aacagataat tggagaatga aaaaattaca tgttatagtc aactcaataa ttttaaggag
    55261 gaattaagta atgaaaagta aatacgaacc attgtttgat aaagtagaat taccaaatgg
    55321 agtagagttg agaaatcgat ttgtgttagc ccctttaaca catatttctt caaatgatga
    55381 tggtactatt tcagatgtag aacttcctta tattgaaaag cgttcacaag atgttggtat
    55441 tacaattaat gctgcgagta atgtgagtga tgtcggaaaa gcatttccag gacagccatc
    55501 aatcgcgcat gacagtgata ttgaaggact aaaacgatta gctacagcaa tgaagaaaaa
    55561 cggtgccaaa gcactcgtac aaatacatca tggcggtgca caagcattgc ctgaattaac
    55621 acctggtgga gacgtcgtag caccaagtcc aatttcttta aaaagtttcg gtcagaaaca
    55681 agaacatagt gctagagaaa tgacgaatga agagattgaa caagcaatca aggattttgg
    55741 tgaagcaacg cgacgtgcaa ttgaagcagg gtttgatggt gttgaaatac atggtgcgaa
    55801 tcattactta attcatcaat ttgtatcacc atactataat agtagaaatg atgtatgggc
    55861 aaatcaatat aaattcccgg tcgctgtgat tgaagaagtg cttaaagcga aagaagcgta
    55921 tggcaataaa gactttatag ttggatacag attgtctccg gaagaagcgg agtctccagg
    55981 aatcacaatg gaaattacag aggaactcgt taataaaatt agccatatgc caatcgacta
    56041 tattcatgtt tcaatgatgg atacgcatgc aacgacacgt gaaggtaaat acgctggaca
    56101 agaaagactg cctttaattc acaaatggat aaatggtcgt atgccactta tcggtattgg
    56161 ttcaattttc acagctgacg aagctttaga tgcagttgaa aatgttggtg ttgacttagt
    56221 agctattggt agagagctac tactggatta tcaatttatt gagaaaatta aagatggacg
    56281 cgaagatgaa attattaatt actttgatcc agagagagaa gataatcatc acttaactcc
    56341 taatttatgg catcaattta atgaagggtt ctatccatta ccacgtaaag ataaataagt
    56401 gtttaactgt taccactaat gatattgtgt atacaatttg ttagtggttt tcaatattta
    56461 taaataaaaa tattcttagt aaaatatact tttgattaag tgtaaaatta tcaattcttt
    56521 tgcttgtaat catttaagta attatgtcat tataaatgta agggttttca aaatagacaa
    56581 aattaatgaa acttagtgat tatttcatct tttttggtgg aaaagtatct gctttgaaaa
    56641 ctaatgtaat tatttggata atgtttcatg tacaatagtt ataaatgatg aaaaggggag
    56701 atatgatgac taaatctgaa aaaattattg agttaacaaa tcattacgga gcacataatt
    56761 atttaccatt gccaattgtc atttcagaag ctgaaggggt atgggttaaa gatcctgaag
    56821 gcaataaata tatggatatg ttatctgcat attccgctgt taaccaaggt catagacatc
    56881 cgaaaattat tcaagcatta aaagatcaag ctgataaagt gactctagtt tcacgtgctt
    56941 ttcatagtga taacttaggt gaatggtacg aaaaaatttg taaactggca ggtaaagata
    57001 aagctttacc aatgaataca ggtgctgaag cagtagaaac agctttgaaa gcagcacgac
    57061 gctgggcata cgatgttaaa ggaattgagc caaataaagc agaaatcatt gcatttaatg
    57121 gtaacttcca tggtcgaaca atggcgccag tttcattatc ttcagaagca gaataccaac
    57181 gtggttatgg tccgttatta gatggattta gaaaagttga ttttggagat gtagatgcat
    57241 tgaaagctgc aattaatgaa aatactgcag cagttttagt agaaccaatt caaggtgaag
    57301 cgggtataaa tataccgcca gaaggatatt tgaaagcaat tagagaatta tgtgatgaac
    57361 ataatgtctt atttattgct gacgaaatcc aagcaggatt aggtcgttcg ggtaaattat
    57421 ttgctacgga ttgggataat gtaaaacctg atgtctatat tttaggtaaa gcactaggtg
    57481 gtggtgtctt cccaatttct gttgtattag cagataaaga agtattagat gtctttacac
    57541 ctggctcaca tggttcaaca tttggtggta atccacttgc ttgtgctgca tcaattgctg
    57601 cattagatgt tatcgttgat gaggatttac cagggcgctc tttagaatta ggagattatt
    57661 ttaaagaaca attaaagcaa attgatcatc catcaattaa agaagtccgt ggacgtggtt
    57721 tgtttatagg tgtggaactt aatgaaagtg ctagaccata ttgtgaagct ttgaaagaag
    57781 aaggcttatt atgtaaagaa acgcatgata ctgtcattcg ttttgcacca ccattaatta
    57841 ttactaaaga agaattggac cttgcacttg aaaaaataag acacgtattt caataatgtc
    57901 aaaaagttgt aacaatcagt ttgtaagggc tttaaaaagg aatacgttat gttacaatat
    57961 gtttgaaagc gaaatcatta ggtaaagaag aggcgaaaag gatcatgact gagaacaata
    58021 atttagtaac ttctactcaa ggaattatta aagaagcatt gcataaattg ggatttgacg
    58081 aaggaatgta cgatttaatt aaagaacctt taagaatgtt acaagtgcgt atccctgtac
    58141 gaatggatga tggtactgtt aaaacattca caggttaccg tgcgcaacat aatgatgctg
    58201 ttggaccaac aaaagggggc gtgcgtttcc acccagatgt tgatgaagaa gaagtaaaag
    58261 cattatcaat gtggatgact ttgaaatgtg gcattgtaaa cttaccatac ggtggtggta
    58321 agggtggtat cgtttgtgat ccacgtcaaa tgagcattca tgaagttgaa cgtttatcac
    58381 gcggatatgt aagagcaatt tcacaattcg taggtccgaa caaagatatt ccagcaccag
    58441 atgtatttac aaactcacaa attatggctt ggatgatgga tgaatatagt gcattagata
    58501 aatttaattc accaggtttc atcacaggta aaccaattgt attgggtggt tctcatggac
    58561 gcgacagatc aactgcacta ggtgtagtta ttgcaattga acaagctgca aaacgtcgta
    58621 atatgcaaat tgaaggtgcc aaggttgtta ttcaaggttt cggtaatgcc ggaagtttct
    58681 tagctaaatt cttatatgat ttaggtgcaa aaattgtagg tatctctgat gcttacggtg
    58741 cattacacga tccaaatggc ttagatatag attatttatt agaccgtcgt gatagttttg
    58801 gtacggtaac aaatttattt gaagaaacaa tctcaaataa agaattgttt gaattagatt
    58861 gtgacatttt agtaccagcg gctatttcaa accaaattac agaagacaat gcacatgata
    58921 ttaaagctag catcgttgtt gaagctgcta atggacctac aacaccagaa gcaacacgta
    58981 ttttaactga acgtggtata ttattagttc cagacgtatt agcaagtgct ggtggtgtaa
    59041 cggtttctta cttcgaatgg gtacaaaata atcaaggtta ttattggtct gaagaagaag
    59101 ttaatgaaaa gctacgtgaa aaattagaag cggcatttga tacgatttac gaattgtctc
    59161 aaaatcgaaa aatagatatg agacttgcag catatatcat aggtattaaa cgtacagcag
    59221 aagcagctag atatcgtggt tgggcataat taattatcat atgtgattta acgagcttgg
    59281 gacagaaaac aaagccctaa gctcgttaat tttattttag cagtagttga ctgaataaaa
    59341 atacacttgt aacaagctta tttcaaaaat agccggggcc ccgaacacag agaatttcta
    59401 attaaacggt caactatata tagttgatta aaaagacagc agtaagatat tttctattcg
    59461 gaaatatctt actgctgtct tttttagtaa tagctatatt tttgtattta tgttttctag
    59521 tttaacaata ctacttaatg acttctttat atttgtcagc gaaatttgta aagacaccat
    59581 caacgccgta tttatttaat cgtaacatat cagctttttc atttactgta taaggatgta
    59641 ctataaaacc taagtctttt aaatgatggg tattttgttc agttaaatct gtataatcag
    59701 gacctaatcc aatcgcataa gagcgtatct cttttaagcg ttggtcgtta aattgttgta
    59761 gttcaccttt atcaactaat tttactaatg gcacatgttt attttgacga tgaattttct
    59821 ttaaactttc gtcagaaaat gattgaatca ttacatgtcc attttttaat ttattgttat
    59881 ttaaaaggtg atgctttttc aatgaagcta ataattgttc ttccattcct gggtatacat
    59941 caggtgactt tgtttcaata taatagtttg cattcgggcc ataacgttct aaaatttcat
    60001 ctaaagtggg tactttagca tttttataac ttgctcttgc gtattttgga tattttttat
    60061 taaaccaact tcctgcatct aactgtttta attcatcaag ggtataatcc tcaactttac
    60121 cgtgtccatt tgttgtacgg ttaacagttt catcatgcat agcaactaaa tggccatctt
    60181 tggtacgttg taaatcaatt tcgatataag atgcttttaa ctcattatga ctcttatcat
    60241 atgcttgaaa cgtatgctcg ggtgcatagc cacttgcgcc acgatgtgcg atagtagtga
    60301 atcgctcatt cgttaaattt gtatgccatt gaatagcctg aggtttattt gcaatttgat
    60361 ttgtttgttc agcgccagca gtaggtactg ataaaaatcc catagtaaaa acagcagaag
    60421 cagccataaa tttagtgaag cttttcgaag agttagtcat agtctttatc ctttcatctc
    60481 tttatttgta gtctaacaat tttaaaatac tacaaaaacc tgcttgtgaa aacgctttac
    60541 acatttcttt tacaatttat aacatttctg taatataaat ttaaaagaat tatcaaacat
    60601 tttaggaatc ttaaaaatgt gattttcaac aagacgaaga gagcattaaa atacccacaa
    60661 tgtaatttta atagacattg tgggtaggta gattaacgta tttattgtga tagtaattgt
    60721 ttagcaacat caagttgttg tttgaccgat gattgacctg ttgaaccgta actttgacgt
    60781 cgttttaaac aattttcagg ctgcaaataa tcgtaaatat cggcatcaat actagaatga
    60841 tgttgttgat atgttgctaa aggaacatct aataaataat gaccttgttg tatacattct
    60901 aagacaattt ttcctacaat ttcatgtgca gttctaaatg gaatattttt agttactaaa
    60961 taatctgcta gttccgttgc atttgaaaaa tcttctttaa cagtttgatt gagttgttct
    61021 ttattaattg tcatcgtttg aatcatacct tcgaaaatac gtaaagaacc tttaattgta
    61081 tggacagcat cgaataaacc ttctttatct tcctgcatat ctttgttata tgctagaggt
    61141 aatcctttta aagtcataag catgctcatt aaatgaccag tcgttcgacc aactttacct
    61201 ctaattaatt ctgccatatc aggatttttc ttttgtggca taatagatga gccagttgaa
    61261 aatgcatctg ataatgtaat gaatttagct tcgtctgtgg accagaaaat aatttcctct
    61321 gcaaagcgtg ataagtgaac catcgttaaa gaaatattat gcaatgtttc aataatatag
    61381 tctctgtcac taacagcatc taggctattc tcatagagac tgccaaagtt caacaatgct
    61441 gttgtctcgt gtctatcgat agggtatgtg gtaccactta aggctgctgc acctaaagga
    61501 ttaatatcga ttcgttttaa actatcttca aatcgttgtt ggtctcgttg taacatccaa
    61561 aaataagtca taatattatg tgcaaatgaa attggctgtg cacgctgtaa atgagtataa
    61621 ccaggcataa ttgtatcaac attattggaa gcgatgtcta caattacact ttgtaacgac
    61681 ttaattaatg cgatgatatc ttgcacttgt ttcttagtgt acaagtgcat atctgttgca
    61741 acttgatcgt ttctactgcg tccagtatgc aacttaccac cagcatcacc aatacgttta
    61801 attaattcat gttcaatatt taaatgaata tcttctaatg atgcactaaa ttgaatttga
    61861 tcttgatgat aatcatgttg aatagatttt agtccttgta taatttgttc gctgtcttgt
    61921 tgactaataa tgccttgatt cgcaagcata gttgcatgtg caatgctgcc ttcgatatct
    61981 tgatctatga gcgtttgatc aaaagtaatg gatgcgttaa agtcgtcaac ccactcttca
    62041 ggttgtactt caaatctacc gccccaagct ttattgctca ttgctatagc ctccatgcaa
    62101 catcgcattt acttgagtag gtaaaccata gatatcgata aagccaacag cagcgtcttg
    62161 attaaatgca tcttcttttg tataagttgc taatttttca tcatataatg tgtaaggtga
    62221 ttttctacca tttacgatgg tattaccttt gaataattta attctgacat caccacttac
    62281 gtattgctga gtactatcaa taaataattt taagctatca gttaaaggtg agaaccaaag
    62341 tccattgtat agttgttcag caaattgctt ctcgatgatt ggtttaaagt gtgcgacatc
    62401 tttcgttaac gtaatcgttt ctaatgcttt atgcgctttt aaaataactt ctgcagcagg
    62461 tgcttcataa atttctcttg atttgatacc tacaagtcta ttttctacat ggtcaattct
    62521 tccgatacca tgcttaccag ctaatgcatt caacgttaaa attaaatcgt ctaattcata
    62581 tgttttgcca tcaatttgaa ctgggatgcc tttatcaaac gttaaaatga tttcatcagc
    62641 agtatctggt gtttcttcta aagcatttgt tagatcgaac gcatcctctg gtggcgcagc
    62701 ataaggatct tctaaaatac cacattcatt cgctctgccc catagatttt gatcgataga
    62761 ataaggtgaa tcatggttga ttgatacagg gatattatgt ttaattgcat aatcgatttc
    62821 ttcttcacga ctccatgccc actcacgtac aggtgcgaat gctttcaatg atgggtttaa
    62881 tgctttaatg gcaacttcga aacgtacttg gtcattccct ttaccagtac aaccatgtgc
    62941 aatacctact gaatttgttt tctcagcaat ctctactaat tttttagcga ttaatggtct
    63001 tgataaagct gaaactaatg gatatgcatt ttcatacatt aaatttcctt tgattgcata
    63061 acttacatac tcatcactaa attcttttgt tgcatcaata atatgacatt caactgctcc
    63121 catatctaaa gcttttttat aaacgatgtc taaatcttta ccttcaccaa catctaggca
    63181 acaagctaca acatcgtatc ctttgtcgat aagccattga acggccacac ttgtatctag
    63241 tcctcctgaa tatgctaaaa caattttctc tttcataaaa ttcacctcat tgtagttatc
    63301 tgaatatttc gtatgaacac atgatagcaa acttttaatg aaaataaaac cattatttta
    63361 catatttatt cataaaatgc gatagagata gttagagttg taagtataaa tgcttattta
    63421 tcaatgttta aaagtatttt aaaaaacatg caaattgtat aaaaaatgtt tgagtgtttg
    63481 acgccagttt gaaatgtttg ttgaaaaata ggtgtgaaac gtcacataaa tatcaatttt
    63541 attgattaag tacaaacttg tgaattgaat cgcaaacgta aacttagtaa aattaagata
    63601 ttaaatgaaa caggaggctt ttatagatga ctcatattca attagatttt agtaaaacgt
    63661 tagaattttt cggtgaacac gaattaaaac aacaacaaga aattgttaaa tcaattcaca
    63721 aaacaattca tgaaggtact ggtgcaggta gtgacttctt aggctgggtt gatttaccag
    63781 ttgattacga caaagaagaa ttttcaagaa ttgttgaagc atcaaaacgc attaaagaaa
    63841 attctgatgt tttagtagtc atcggtattg gtggttctta cttaggtgca cgtgcagcaa
    63901 tcgaaatgtt aacgtcatca tttagaaaca gcaatgaata ccctgaaatt gtatttgttg
    63961 gtaatcactt gtcatcaaca tatacgaaag agttagttga ttatttagca gacaaagatt
    64021 tctctgtaaa cgttatttct aaatctggta caactacaga accagcagtt gcatttagat
    64081 tgttcaaaca attagttgaa gaaagatacg gtaaagaaga agcacaaaaa cgtatatttg
    64141 caacaacgga taaagaaaaa ggtgctttaa aacagttggc tacaaacgaa ggttatgaaa
    64201 cgtttatcgt acctgatgat gtaggtggaa gatattcttt tttaacagca gtaggattat
    64261 taccaattgc aacagctgga attaacatcg aagctatgat gattggtgct gcaaaagcac
    64321 gtgaagaatt atcttcagat aaattagaag aaaacattgc atatcaatat gcgacaattc
    64381 gaaacatttt atatgcaaaa ggttatacaa cagaaatgtt gattaactat gaaccatcta
    64441 tgcaatactt taatgaatgg tggaaacaat tatttggtga atcagaaggt aaagacttca
    64501 aaggtatcta tccttcaagt gccaactaca caactgattt acattcttta ggtcaatatg
    64561 tacaagaagg acgtcgtttc ttattcgaaa cagttgtaaa agtaaatcat cctaaatatg
    64621 atattactat tgaaaaagat agtgatgatc tagacggatt aaattattta gctggtaaaa
    64681 caatcgacga agttaacaca aaagcattcg aaggtacatt attagcacat actgatggtg
    64741 gtgttcctaa catggtagtg aacattccac aattagatga agaaactttc ggttatgtcg
    64801 tatacttctt cgaacttgct tgtgcaatga gtggatacca attaggcgta aatccattta
    64861 accaacctgg tgtagaagca tataaacaaa acatgttcgc attattaggt aaacctggtt
    64921 ttgaagactt gaaaaaagaa ttagaagaac gtttataaaa tacattactt caaagattag
    64981 tgaagtttga aaagatagaa ctagacgtta actatttaaa gcatattttc gaggttgtca
    65041 ttacaaatgt aaaaatgtaa tgacaacctc gtttttattt atatgcaaga actaggttac
    65101 tagctaatgt gacaagatgt taagagaaaa ttaaagaaaa aataacatct gtcatacaat
    65161 aatattgtta tactactaga gactgattta ttagcatgat tacatgttaa tgtttcttta
    65221 cttagtaatt aactttataa tgtaagaata attatcttca gccaaagaaa gggattgatg
    65281 atttgtcgtt tcatcaagta gaagaatggt ttgagatatt tcgacagttt ggttatttac
    65341 ctggatttat attgttatat attagagcga taattccagt atttccttta gcactctata
    65401 ttttaattaa cattcaagct tatggaccta ttttaggtat attgattagt tggcttggat
    65461 taatttctgg aacatttaca gtctatttga tctgtaaacg atgggtgaac actgagagga
    65521 tgcagcgaat taaacaacgt actgctgttc aacgcttgat tagttttatt gatcgccaag
    65581 gattaatccc attgtttatt ttactttgtt ttccttttac gccaaataca ttaataaatt
    65641 ttgtagcgag tctatctcat attagaccta aatattattt cattgttttg gcatcgtcaa
    65701 agttagtttc aacaattatt ttaggttatt taggaaaaga aattactaca attttaacgc
    65761 aacctttaag agggatatta atgttagttg tgttggttgt attttggatt gttggaaaaa
    65821 agttagaaca gcattttatg gggtcgaaaa aggagtgaca tcgtgaaaaa agttgtaaaa
    65881 tatttgattt cattgatact tgctattatc attgtactgt tcgtacaaac ttttgtaata
    65941 gttggtcatg tcattccgaa taatgatatg tcaccaaccc ttaacaaagg ggatcgtgtt
    66001 attgtaaata aaattaaagt tacatttaat caattgaata atggtgatat cattacatat
    66061 aggcgtggta acgagatata tactagtcgg attattgcca aacctggtca atcaatggcg
    66121 tttcgtcagg gacaattata ccgtgatgac cgaccggttg acgcatctta tgccaagaac
    66181 agaaaaatta aagattttag tttgcgcaat tttaaagaat tagatggaga tattataccg
    66241 cctaacaatt ttgttgtgct aaatgattat gataacaatc agcatgattc tagacaattt
    66301 ggtttaattg ataaaaagga tattattggt aatataagtt tgagatatta tcctttttca
    66361 aaatggacga ttcagttcaa atcttaaaaa gaggtgtcaa aattgaaaaa agaattattg
    66421 gaatggatta tttcaattgc agtcgctttt gtcattttat ttatagtagg taaatttatt
    66481 gttacgccat atatgattaa aggtgaatca atggatccaa ctttgaaaga tggtgagcga
    66541 gtagctgtaa acattattgg atataaaaca ggtggtttgg aaaaaggtaa tgtagttgtc
    66601 ttccatgcaa acaaaaatga tgactatgtt aaacgtgtta tcggtgttcc tggtgataaa
    66661 gtagaatata aaaatgatac attatatgtc aatggtaaaa aacaagatga accatattta
    66721 aactacaatt taaaacataa acaaggtgat tatattactg ggactttcca agttaaagat
    66781 ttaccgaatg cgaatcctaa atcaaatgtc attccaaaag gtaaatattt agtgcttgga
    66841 gataatcgtg aagtaagtaa agatagccgt gcgtttggcc tcattgatga agaccaaatt
    66901 gttggcaaag tttcatttag attctggcca tttagtgaat ttaaacataa tttcaatcct
    66961 gaaaacacta aaaattaata tgaaacaaat aaaacatcgt ttgtcggttt taatactgat
    67021 aaacgatgtt ttattttgtt agtaccacaa taaaagctaa gttcgaaatg aacttataat
    67081 aaatcaatca caatcacttt gtgttaaaat atgtgtcaaa ggaagtgagg gtttgtcatg
    67141 acattacatg cttatttagg aagagcagga acaggtaagt ctacgaaaat gttaaccgaa
    67201 ataaaacaaa aaatgaaaca ggatccgctt ggagatccaa tcattttaat tgcgccaact
    67261 caaagtacat ttcaattaga acaagccttt gtcaatgatc cggaattaaa tggtagttta
    67321 agaacagaag tgttgcattt tgaacgatta agtcatcgta ttttccaaga agttggtagt
    67381 tatagcgaac aaaagttatc taaagctgca acggaaatga tgatttataa cattgttcaa
    67441 gaacaacaaa agtatttaaa actttatcaa tcacaagcaa aatattatgg ttttagtgaa
    67501 aaattaacag aacaaattca agattttaaa aaatatgcag taacgcctga acatttagaa
    67561 cactttattg ctgataaaaa tatgcaaact cgaactaaaa ataagttaga ggatattgct
    67621 ttaatatacc gtgagttcga acaacgcatt caaaacgagt ttattacggg tgaggattca
    67681 ttacaatatt ttattgattg tatgccgaaa tcagagtggc taaaacgtgc tgatatatat
    67741 attgatggtt ttcacaactt ttcaacgatt gagtatttaa taatcaaagg attaattaaa
    67801 tatgcgaaga gtgtcacaat tatattgacg acagatggta accacgatca atttagttta
    67861 tttagaaaac catcggaagt gttacgacat attgaagaaa tagcaaatga actcaatatt
    67921 tctattgaac gtcaatattt caagcaatta tatcgcttca ataatcaaga tttaaagcat
    67981 cttgaacaag aatttgatgc acttcaaatc aatcgagtgg catgtcaagg tcatatcaat
    68041 attttagaat ctgcgactat gagagaggaa ataaatgaaa ttgcgcgacg tatcatcgtt
    68101 gatattcgtg ataagcaatt acgatatcaa gatattgcta ttttatatcg tgatgaatct
    68161 tatgcttatt tatttgattc catattaccg ctttataata ttccttataa tattgataca
    68221 aagcgttcga tgacacatca tccggtcatg gaaatgattc gttcattgat tgaagttatt
    68281 caatctaatt ggcaagtgaa tccaatgcta cgcttattga agactgatgt gttaacggca
    68341 tcatatctaa aaagtgcata cttagttgat ttacttgaaa attttgtact tgaacgtggt
    68401 atatacggta aacgttggtt agatgatgag ctatttaatg tcgaacattt tagcaaaatg
    68461 gggcgtaaag cgcataaact gaccgaagat gaacgtaaca catttaaaca agtcgttaag
    68521 ttaaagaaag atgtcattga taaaatttta cattttgaaa agcaaatgtc acaagcggaa
    68581 actgtaaaag actttgcaac tgctttttat gaaagtatgg aatatttcga actgccaaat
    68641 caattgatga cagagcgaga tgaacttgat ttaaatggta atcatgaaaa ggcggaggaa
    68701 attgatcaaa tatggaatgg cttaattcaa atccttgatg acttagttct agtatttgga
    68761 gatgaaccaa tgtcgatgga acgtttctta gaagtatttg atattggttt agaacaatta
    68821 gaatttgtca tgattccaca aacattagat caagttagta ttggtacgat ggatttggct
    68881 aaagtcgaca ataagcaaca tgtttactta gttggaatga acgacggcac catgccacaa
    68941 ccagtaactg catcaagttt aattactgat gaagaaaaga aatattttga acaacaagca
    69001 aatgtagagt tgagtcctac atcagatatt ttacagatgg atgaagcatt tgtttgctat
    69061 gttgctatga ctagagctaa gggagatgtt acattttctt acagtctaat gggatcaagt
    69121 ggtgatgata aggagatcag cccattttta aatcaaattc aatcattgtt caaccaattg
    69181 gaaattacta acattcctca ataccatgaa gttaacccat tgtcactaat gcaacatgct
    69241 aagcaaacca aaattacatt atttgaagca ttgcgtgctt ggttagatga tgaaattgtg
    69301 gctgatagtt ggttagatgc ttatcaagta attagagata gcgatcattt aaatcaaggt
    69361 ttagattatt tgatgtcagc attaacgttt gacaatgaaa ctgtaaaatt aggtgaaacg
    69421 ttgtctaaag atttatatgg taaggaaatc aatgccagtg tatctcgatt tgaaggttat
    69481 caacaatgcc catttaaaca ctatgcctca catggtctta aactaaatga gcgaacgaag
    69541 tatgaacttc aaaactttga tttaggtgat attttccatt ccgttttaaa atatatatct
    69601 gaacgtatta atggcgattt taaacaatta gacctgaaaa aaataagaca attaacgaat
    69661 gaagcattgg aacaaatttt acctaaagtt cagtttaatt tattaaattc ttcagcttac
    69721 tatcgttatt tatcaagacg cattggcgct attgtagaaa caacactaag cgcattaaaa
    69781 tatcaaggca cgtattcaaa gtttatgcca aaacattttg agacaagttt tagaaggaaa
    69841 ccaagaacaa atgacgaatt aattgcacaa acattaacga caactcaagg tattccaatt
    69901 aatattagag ggcaaattga ccgtatcgat acgtatacaa agaatgatac aagttttgtt
    69961 aatatcattg actataaatc ctctgaaggt agtgcgacac ttgatttaac gaaagtatat
    70021 tatggtatgc aaatgcaaat gatgacatac atggatatcg ttttacaaaa taaacaacgc
    70081 cttggattaa cagatattgt gaagccaggt ggattattat acttccatgt acatgaacct
    70141 agaattaaat ttaaatcttg ggcagatatt gatgaagata aattagaaca agatttaatt
    70201 aaaaagttta agctgagtgg tttagtgaat gcagaccaaa ctgttattga tgcattggat
    70261 attcgtttag aacctaaatt cacttcagat attgtaccag ttggtttgaa taaagatggc
    70321 tctttgagta aacgaggcag tcaagttgca gatgaagcaa cgatttataa attcatccaa
    70381 cataacaaag agaattttat agaaaccgct tcaaatatta tggatggaca tactgaagtt
    70441 gcaccattaa agtacaaaca aaaattgcca tgtgcttttt gtagttatca atcggtatgt
    70501 catgtagatg gcatgattga tagtaagcga tatcgaactg tagatgaaac aataaatcca
    70561 attgaagcaa ttcaaaatat taacattaat gatgaatttg ggggtgagca atagatgaca
    70621 attccagaga aaccacaagg cgtgatttgg actgacgcgc aatggcaaag tatttacgca
    70681 actggacaag atgtacttgt tgcagccgcg gcaggttcag gtaaaacagc tgtactagtt
    70741 gagcgtatta tccaaaagat tttacgtgat ggcattgatg tcgatcgact tttagtcgta
    70801 acgtttacaa acttaagcgc acgtgaaatg aagcatcgtg tagaccaacg tattcaagag
    70861 gcatcgattg ctgatcctgc aaatgcacac ttgaaaaacc aacgtatcaa aattcatcaa
    70921 gcacaaatat ctacacttca tagtttttgc ttgaaattaa ttcaacagca ttatgatgta
    70981 ttaaatattg acccgaactt tagaacaagc agtgaagctg aaaatatttt attattagaa
    71041 caaacgatag atgaggtcat agaacaacat tacgatatcc ttgatcctgc ttttattgaa
    71101 ttaacagagc aattgtcttc agatagaagt gatgatcagt ttcgaatgat tattaaacaa
    71161 ttgtatttct ttagcgttgc aaatccaaat cctacaaatt ggttggatca attggtgaca
    71221 ccatacgaag aagaagcaca acaagcgcaa cttattcaac tactaacaga cttatctaaa
    71281 gtatttatca cagctgccta tgatgcttta aataaggcga atgatttgtt tagtatgatg
    71341 gatggcgtcg ataaacattt agctgttata gaagatgaac gacgtttaat ggggcgtgtt
    71401 ttagaaggtg gctttattga tataccttat ttaactggtc acgaatttgg cgcgcgtttg
    71461 cctaatgtaa cagcgaaaat taaagaagca aatgaaatga tggtcgatgc cttagaagat
    71521 gctaaacttc agtataaaaa atataaatca ttaattgata aagtgaagag tgattacttt
    71581 tcaagagaag ctgatgattt gaaagctgat atgcaacaat tggcgccacg agtaaagtac
    71641 cttgcgcgta ttgtgaaaga tgttatgtca gaattcaatc gaaaaaagcg tagcaaaaat
    71701 attttagatt tttctgatta tgaacatttt gcattacaaa ttttaactaa tgaggatggt
    71761 tcgccttcag aaattgccga atcataccgt caacacttcc aagaaatatt ggtcgatgag
    71821 tatcaagata cgaaccgagt tcaagagaaa atactatctt gcataaaaac gggtgcagaa
    71881 cataatggta atttatttat ggttggagat gttaagcaat ccatttataa atttagacaa
    71941 gctgatccaa gtttatttat tgaaaagtat caacgcttta ctataaatgg agatggcact
    72001 ggacgtcgaa ttgatttgtc gcaaaacttc cgttctcgaa aagaagtact gtcaacgact
    72061 aactatatat tcaaacatat gatggatgaa caagtcggtg aagtaaatta tgatgaatca
    72121 gcacaattgt attatggtgc accatatgat gaatcggacc atccagtaaa cttaaaagtg
    72181 cttgttgaag cggatcaaga acatagtgat ttaactggta gtgaacaaga agcgcatttt
    72241 atagtagaac aagttaaaga tatcttagaa catcaaaaag tttatgatat gaaaacagga
    72301 agctatagaa gtgcgacata caaagatatc gttattctag aacgcagctt tggacaagct
    72361 cgcaatttac aacaagcctt taaaaatgaa gatattccat tccatgtgaa tagtcgtgaa
    72421 ggttactttg aacaaacaga agtccgctta gtattatcat ttttaagagc gatagataat
    72481 ccattacaag atatttattt agttgggtta atgcgctccg ttatatatca gttcaaagaa
    72541 gacgaattag ctcaaattag aatattgagt ccaaatgatg actacttcta tcaatcgatt
    72601 gtaaattaca ttaatgacga agtagcagat gctattttag ttgataaatt aaagatgttt
    72661 ttatcagata ttcaaagtta ccaacaatat agtaaagatc atccggtgta tcagttaatt
    72721 gataaatttt ataatgatca ttatgttatt caatacttta gtggacttat tggtggacgt
    72781 ggacgacgtg caaaccttta tggtttattt aataaagcta tcgagtttga gaattcaagt
    72841 tttagaggtt tatatcaatt tattcgtttt atcgatgaat tgattgaaag aggcaaagat
    72901 tttggtgagg aaaatgtagt tggtccaaac gataatgtcg ttagaatgat gacaattcat
    72961 agtagtaaag gtctagagtt tccatttgtc atttattctg gattgtcaaa agattttaat
    73021 aaacgtgatt tgaaacaacc agttatttta aatcagcaat ttggtctcgg aatggattat
    73081 tttgatgtgg ataaagaaat ggcatttcca tctttagctt cggttgcata taaagctgtt
    73141 gccgaaaaag aacttgtgtc agaagaaatg cgattagtct atgtagcatt aacaagagcg
    73201 aaagaacaac tttatttaat tggtagagtg aaaaatgata aatcgttact agaactagag
    73261 caattgtcta tttctggtga gcatattgct gtcaatgaac gattaacttc accaaatccg
    73321 ttccatctta tttatagtat tttatctaaa catcaatctg cgtcaattcc agatgattta
    73381 aaatttgaaa aagatatagc acaagttgaa gatagtagtc gtccgaatgt aaatatttca
    73441 attatatact ttgaagatgt gtctacagaa accattttag ataataatga atatcgttcg
    73501 gttaatcaat tagaaactat gcaaaatggt aatgaggatg ttaaagcaca aattaaacac
    73561 caacttgatt atcaatatcc atatgtaaat gatactaaaa agccatcaaa acaatctgtt
    73621 tctgaattga aaaggcaata tgaaacagaa gaaagtggca caagttacga acgagtaaga
    73681 caatatcgta tcggtttttc aacgtatgaa cgacctaaat ttctaagtga acaaggtaaa
    73741 cgaaaagcga atgaaattgg tacgttaatg catacagtga tgcaacattt accattcaaa
    73801 aaagaacgca tatctgaagt tgagttacat cagtatatcg atggattaat cgataaacat
    73861 attatcgaag cagatgcgaa aaaagatatc cgtatggatg aaataatgac atttatcaat
    73921 agtgagttat attcgattat tgctgaagca gagcaagttt atcgtgaatt accgtttgta
    73981 gttaaccaag cattagttga ccaattgcca caaggagacg aagacgtctc aattattcaa
    74041 ggtatgattg acttaatctt tgttaaagat ggtgtgcatt attttgtaga ctataaaacc
    74101 gatgcattta atcgtcgccg tgggatgaca gatgaagaaa ttggtacaca attaaaaaat
    74161 aaatataaga tacagatgaa atattatcaa aatacgcttc aaacgattct taataaagaa
    74221 gttaaaggtt atttatactt cttcaaattt ggtacattgc aactgtagta ttttgatttt
    74281 caaaagaata aaaaaatttc gattaagtgc aaagcccttg tagcagaatg aacacaactc
    74341 attttcaaaa ttgtcttact tatttatttg ttatttgata acgaaaaaag ttataatgtg
    74401 aattaagata aagatgagga gttgagaatg aatgaaattc ttatcattca agtataatga
    74461 caaaacttca tatggcgtta aagtaaaacg cgaagatgct gtatgggatt taacacaagt
    74521 atttgctgac tttgcagaag gagatttcca tcctaaaaca ttgttagctg gtttacaaca
    74581 aaatcatact ttagattttc aagaacaagt acgtaaagca gttgtagcag cagaagatag
    74641 cggcaaagct gaagactata aaatttcatt taatgacatt gaattcttac caccagtaac
    74701 acctccgaat aatgtgattg cttttggtag aaattacaaa gatcatgcga acgaattaaa
    74761 tcatgaagta gaaagattat atgtatttac aaaagcagcg tcatctttaa caggagataa
    74821 tgcaacaatt ccaaatcata aagatattac tgatcaatta gattatgaag gtgaattagg
    74881 tattgttatt ggtaagtctg gtgaaaagat tccaaaagca ttagctttag attatgttta
    74941 cggctataca attattaacg atatcactga tcgcaaagca caaagtgaac aagatcaagc
    75001 atttttatca aaaagtttaa ctggcggttg cccaatgggt ccttatatcg ttactaaaga
    75061 cgaactacca ttacctgaaa atgtaaatat tgttacaaaa gttaacaatg aaattagaca
    75121 agatggtaac actggcgaaa tgattcttaa aattgatgaa ttaatagaag aaatttcaaa
    75181 atatgttgca ctacatccgg gagatattat tgcaactggt acaccagcag gcgttggtgc
    75241 aggtatgcaa ccacctaaat tcttacaacc aggtgatgaa gttaaagtga ctattgataa
    75301 tattggaacg ctgacaactt atatcgctaa ataattatca tttaaaaagc taaccagtct
    75361 ttatatagat tggttagttt tttgcttttc taataaggtg ttaaagatca ttgtttataa
    75421 tgttaccatt ttgagatgaa agtgaaatat tgatattaag aagtagttga ttattttaca
    75481 gcagatgcac aatattctaa taaggaataa aatgtcatgt tcttcctctc aaatatagaa
    75541 gtgtggtaga atatatattc gtgtataatc aaatcatgat taaattacaa gcaagtgggt
    75601 attaatccca agaagcttta atttaataat ataaattatt aaagtggggg gaatcagtat
    75661 gttacattta catatattaa gttgggtatt agcgattatt ttatttatcg ctacatactt
    75721 aaacatttca aaaaatcaag gcggatcacc atttttcaaa ccgttgcaca tgattttacg
    75781 cttatttatg ctgttgacgt taatttcagg attttggata ttaattcagt catttatgaa
    75841 tggcggggca aatcatatgt tgcttacatt gaaaatgctg tgtggtgttg cagtagttgg
    75901 attgatggaa gtgtcgattg ctaaaagaaa gagacatgaa caaagtcaca caatgttttg
    75961 gataacaatt gcattaatta tcatcacaat ggtattaggt gtcattctac cgttagggcc
    76021 tatatcaaaa ttattcggta ttggctaatt gataagacat atagtttatg acataaggca
    76081 tggacaatta ttagtccaag accttatgtc ttttttgatt ttaaaaatgt taaacataaa
    76141 aaatggactg gatagtagta ccagtccaac ataattctaa cctagacaat taagattaga
    76201 ttgaatcgca tgattcattt atttagcttt gtaaccaatc atattgatta aatctttagg
    76261 gtggctatat ggtggtgcat aagccacttc aaactcagtt aactcatcta cagttagctg
    76321 gttcatcatt gccatcgata gtacatcaat acgtttatct gcaccttctt ttcctactgc
    76381 agctgctctt aaaatctgac ggtttgaagt gtcataatat actcttaagt gtaaagggga
    76441 atttcctggg taataattcg cgtgtgcacc ttgagtgact tccaccattt tatagtcaaa
    76501 ttgcttcagt tcgtttggtt taacgccgac actcgcaaat gtataatcaa agaacttcac
    76561 aatattgttg cctaagaagc ctttgaattc aatagtgtca tttccagcaa tttgttcggc
    76621 aacaatactt gctgcacggt gagcgcccca agctaaagga acactagccg ttagatcgac
    76681 atgtcgataa tgtgatgttg caatatctcc tattgcataa atgtttggaa catttgtttc
    76741 aaatttatcg tttaccggta tgaagccttt tcgatcaagt ttgatatttg aactttcgat
    76801 aaattttgaa ttggggtgag taccgacacc ttcaataatc atatcgtaat gttcaacttt
    76861 tcctgattta aatgtaattt catttccatt gatagcatca atttcctcat ttaaacggta
    76921 tggaatctcc cgcttatcta attcatcaag tataggttga ttcatgtcgg tatccattaa
    76981 tttatttatc ttatcagatc gatgaattaa agtagggtgt aaaccacgtt cataaagatt
    77041 ttcaagaact tctaatgaaa cataccctgc acctacaacc aatactttat caacttgatt
    77101 tgctttgatg aattgatcga tagcatcagt gtcttctaaa tttctaagtg taaatgtaat
    77161 atcactctca aagccaaggc tatttgcact tgcaccaggg cttaaaatga gtttatcgta
    77221 agattcttca aattgttcgt tggtctttct atttaataca gttacagttt gtctttcatc
    77281 attgattgca ataacttcat gataagtttt tactgtgatt tgctttctat cataaaattt
    77341 ttcaggtgta tacgctaaag catattttct atcttcaaca acttcgccaa tgacataagg
    77401 caatgcacaa ttagcaaagc tcatatcacg atctttttca aaaataataa tgtcactttc
    77461 tttatctaaa cgtcgaattt ggctggcaca tgttgcaccg ccagcgaccg ctccgactac
    77521 gactattttg ggcatcgtaa cttacctcct attgttttaa aatattataa aatgattagt
    77581 tataaattaa cagtaatatc taatatttaa attaaagaaa tcattcaaat atcgaccaat
    77641 gccatcttca ttattgttga atgtaatatt attcgctaca tctttaagtt cttgcaaacc
    77701 attttccata gcaacaccat ggcgggcgta ctcaatcatt tcaatatcat tatcttcatc
    77761 accgaatgca ataatattat ttcggtcaat atttaaaaat tgtctaactt gctcaatgcc
    77821 tcttgcttta ttaataccaa gttttacaat ttcaatgaca gggaatggtg cgccccagcg
    77881 tcgatgctca atatgatcgg cataaaaatg agtaagcata tttttgattt caggtatttt
    77941 actttcttcg gcttcaatta aaattgaggt aggggattct ttcaagtgga caagtaaatt
    78001 accagtttga attcttggat tacccattga aaaaccttca aataatcttg gatcatgatt
    78061 gttaatgaaa acataatctt tcacttctgc tataatattc gatacttgat attgttgtaa
    78121 tccttgaata atgttttgtg cgatgcctaa atctaaaatt tcatggcaag ttttgaagtt
    78181 tttatcttta gggtgatgta cgtaagcgcc attaaaatta acaattggtg tcgttaaatt
    78241 taattcatga taatacattt gacttgcacg ataaggtctg ccagtcgcaa tcataatttg
    78301 gtgtccacgt tgttgtaatt catttaatac ttgtttagta tatgatgaaa tttctttgtt
    78361 atcgtttaat aatgttccgt ctaagtctag acatattaaa tgtggttgca tatctctctc
    78421 ctcataagtt gcttagttca tatagataca tcatagcatt ttattggcgt tttgtcggat
    78481 atttgatata ttatgaataa tatgacatta aagaggtgat atggatggaa gaggcattga
    78541 aagatagtat cttaggtgca ttagaaatgg taattgaccc tgaattagga attgatatcg
    78601 ttaatttagg tttagtatac aaagtgaatg ttgatgatga aggcgtatgt acagttgata
    78661 tgactttaac atcaatggga tgtccaatgg gacctcaaat tattgatcaa gttaaaacag
    78721 tattagcaga gattcctgaa attcaggata ctgaagtgaa tatcgtatgg agtccacctt
    78781 ggacaaaaga tatgatgtca cgttacgcta agattgcact tggtgtgagc taacataaac
    78841 gtgcattgcc tgtagaaatt ggaaatccaa ttggggatcc gctcccaact tgcattgctt
    78901 gtagaatttc ttttcgaaat tctctgtgtt tgggcccgct ccccaactcg cattgcttgt
    78961 agaatttctt tttgaaattc tctgtgtttg ggccccgcag tcaatataac cttgtagagt
    79021 ataattcatt gtgaataagc tcccttcaaa gtagacattg aaaaatgaaa attttgaagg
    79081 gagccttatt tatgttctag gttctgattt tattttgaaa atttatatct aacttgtttc
    79141 aaaaaatatg aattaagaca gtgtttctca cttctaagag cgcacaattc attttctagt
    79201 tgaatatttt cttgaaaatt tttataataa atttaattta tattacagtt atattacaat
    79261 acataatact tcatagtttt taagttgccg agttgcatta caaattggat ttcgaagtaa
    79321 gaatcatcat tggtaatttt tttaatttaa cagtatttta gtcaatatga ttttgatgat
    79381 gtcgtaattc aataatatac atatgcattt caatattctt ttaaacagca taactaaatt
    79441 taattaagca tctaagaaga acagttttaa aagggaagaa tgcaaaaatg aacaaaacaa
    79501 agggttttac aaagtataag aaaatgagat atatgccagg gctcgatggt ttgagggcaa
    79561 tcgctgttct aggaattatt atttaccact taaataagca atggttgaca ggtggctttt
    79621 taggtgtgga tacatttttt gtgatctctg gttatttaat tacgagctta ttactaaaag
    79681 agtatgatga cacaggtatc attaaattga aaagcttttg gatacgtcgt ttaaaacgtt
    79741 tattaccagc agtcatagtt ttattaatgg ttgtagggac agcaacctta ttattaaaat
    79801 cagataatat cattagggtt aaacatgata ttattgctgc gatattttat gtatcaaact
    79861 ggtggtatat agcaaaagat gttaattatt ttgagcaatt ttcatttatg ccattaaagc
    79921 atttatggtc tttagcaatt gaagaacagt tttacatatt tttcccagtt attttggtta
    79981 cattattgtt aacaattaaa aagcgataca aaataggatt tatttttttg ggagtatcaa
    80041 taatttcttt agggttaatg atgtttatct acagtattaa tggggatcat tcacgagtgt
    80101 attttggtac agatactaga ttacagacat tgttactggg tgttatttta gcttttttat
    80161 ggccaccgtt taaattgaaa aatgatccac ctaaagttgt aaaatatgtt attgatagca
    80221 taggtagttt atcatttata atacttatat tattattttt cattattaat gatgagacga
    80281 attggatata tgatggtggt ttctatttaa tatccatatt aacgttattt attattgcca
    80341 gtgtcgttca tccatctaca tggatagcga agatattttc aaatccagtg ttagtattta
    80401 tcgggaaaag gtcttatagt ttatatttat ggcattttgc agtaattagt ttcgtacata
    80461 gttactatgt agacggacag atacctgtat atgtgtactt tatagatata agtttaacaa
    80521 ttatatttgc agagctatca tatcgcttta tagaaactcc atttagaaaa gaaggtatta
    80581 aagctttaaa ttggcgacct tcttatatac cacaatttat aagaatggca attgtagtaa
    80641 ccttgttaat tccatttatg ttgattttag taggtgcatt caataaatat ggtaaagaca
    80701 ttattggaga aaaagcgaat agctttgata ccactattga agataattat ttaatgcgga
    80761 tagcaccaat tgataacata cacattgatg gcttagtaag tgagaagaaa aaggaatctt
    80821 ccgacgtata taataatatt aaacctcttt taatcggtga ttcagtaatg gttgatatcg
    80881 gtgagtcatt taagtcatca gttcctaagt ctagaattga tggaaaagta gggcgtcaat
    80941 tgtatcaaac cttaccttta gttaaagcga attattcaca atataaaaaa tcatctgatc
    81001 aagtcgtatt agaattaggt acaaatggcg actttactgt caaacagctc gacgatttac
    81061 taaatcaatt tggaaaagcc aagatttatt tagttaatac acgtgttcca agaatttatg
    81121 aggcaaatgt aaatcgatta ttagctgacg cagcgaaacg aaagtccaat gtcacattaa
    81181 ttgattggta taagcgatca caaggacata gtgaatattt tgcaccagac ggtgtacatt
    81241 tagagtacaa aggagtccta gctttaaaag atgaaatatt aaaagcactt aaaaagaaat
    81301 aacatatgtt taataagtct agttaatgtg taacgtaaca ttagctagat ttttttaatt
    81361 caaaaaatta tttacaaata ttaggaaatt taagtgtaaa agagttgata aatgattata
    81421 ttgggactat aatataatta aggtcaaaga aagtcaaagt caaaagtgca acttgaccaa
    81481 ctctacaaat tagaggtgaa attatatgga tataaataaa atgacatatg ctgttcaaag
    81541 tgctttacaa caagcagttg aactgagtca gcaacataaa ttacaaaata tagaaattga
    81601 ggcaatttta agcgctgcct taaatgaaag tgaaagctta tataaaagta ttttagaacg
    81661 agcaaatatt gaggtagatc aattaaacaa agcttatgaa gacaaactaa acacgtatgc
    81721 atctgtagaa ggtgacaata tacaatatgg tcaatatatt agccaacaag caaaccaatt
    81781 gataactaag gctgaatcat acatgaaaga atatgaagat gaatatattt caatggagca
    81841 tattttacgt tcggcaatgg acattgatca aacaacaaaa cattatataa ataataaagt
    81901 agaagttatc aaagaaatta ttaaaaaagt aagaggggga aatcacgtga catcacaaaa
    81961 tccagaagtt aattacgaag cattagctaa atatggccgc gacttagtag aagaagttag
    82021 acaaggtaaa atggatcctg ttataggaag agatgaagaa attcgaaata cgattcgtat
    82081 tttaagtcgt aaaactaaaa acaaccctgt gctcattggt gaaccaggtg ttggtaaaac
    82141 tgcaattgtt gaaggattag cgcagcgtat agttaagaaa gatgtgccag aatcattatt
    82201 agataaaact gtttttgagt tagatttaag cgcattagta gcgggcgcta aatatcgtgg
    82261 tgaatttgaa gagagattaa aagcagtcct aaaagaagtt aaagagtctg atggtagaat
    82321 tatattattt attgatgaaa tccatatgct tgttggtgct ggtaaaacag atggtgccat
    82381 ggatgcaggc aacatgctaa aaccaatgtt agcacgagga gagttacatt gtattggtgc
    82441 aacaacttta aatgaatatc gagaatatat tgaaaaagat tcggcattag agcgtcgttt
    82501 ccaaaaagta gcagttagtg agcctgatgt tgaagataca atttcaattt tacgtggttt
    82561 aaaagaacga tatgaagtgt atcatggtgt gcgtattcaa gatagagcct tagttgctgc
    82621 cgctgaattg tctgatcgtt acatcactga tcgtttttta ccagataaag cgattgattt
    82681 agttgaccaa gcatgtgcaa caattcgtac ggaaatggga tcaaatccaa ctgaattgga
    82741 tcaagttaat agacgtgtca tgcaattaga aattgaagaa agcgcactta aaaatgaatc
    82801 tgacaatgcg agcaaacaga gattacaaga actacaagaa gagcttgcca atgaaaaaga
    82861 gaaacaagca gcacttcaat ctcgtgtaga atcagaaaaa gaaaaaatag caaatttaca
    82921 agaaaaacgt gcgcaactag atgaaagtag acaagcgttg gaagatgcac aaacaaataa
    82981 caatttagaa aaagctgctg aactacaata tggaacaatt cctcaattgg aaaaagaact
    83041 tagagaatta gaggataatt tccaagatga gcaaggtgaa gatacagatc gaatgattcg
    83101 tgaagttgta acagacgaag aaattggcga tattgtcagc caatggacag gcataccagt
    83161 ttcaaaatta gttgaaacag aacgtgaaaa attacttcac ttaagtgaca tcttgcataa
    83221 acgtgttgta ggtcaagata aagcggttga cctggtttca gatgcagtag ttagagcaag
    83281 agcaggtatt aaagatccaa acagacctat tggtagtttc ttattcctag gtccaactgg
    83341 agtaggtaaa actgaattag ctaaatcatt agctgcatca ttatttgatt ctgaaaaaca
    83401 tatgattcgt attgatatga gtgaatatat ggaaaaacat gcagtatcaa gattgatagg
    83461 ggcacctcca ggatatattg gacatgatga agggggtcaa ttaactgaag cggttcgtcg
    83521 taatccatac tcagttattt tattagatga ggttgaaaaa gcgcatactg acgtctttaa
    83581 tgtattattg caaattttag atgaaggtcg tttaactgat tctaaaggac gtagcgttga
    83641 ttttaaaaat actattatta ttatgacaag taatattgga tctcaagttt tattagaaaa
    83701 cgtaaaagag actggtgaaa ttacagaatc aacagaaaaa gctgttatga caagtttaaa
    83761 tgcatatttc aaaccagaaa ttttgaatcg tatggatgat atcgtattat ttaaaccatt
    83821 atctattgat gacatgagta tgattgtaga taaaatctta acgcaattaa atataagatt
    83881 actagaacaa cgaatctcaa ttgaagtttc tgatgatgct aaagcttggc taggtcaaga
    83941 ggcttatgaa cctcaatacg gtgcaagacc attaaaacgt tttgtacaac gccaaattga
    84001 aacaccatta gcacgtatga tgattaaaga gggattccca gaaggtacaa cgattaaagt
    84061 taatttaaat tcagacaata acttaacgtt taatgttgaa aaaattcatg aataaaattg
    84121 aaccaagaat gtgatgatta atcgcattct tggtttttta gatttgaaat ttattataat
    84181 tgttcattgg caatatactt tttaaatgat ctaataaacg ccaatatttc tggactttct
    84241 tttttgctgt atatatatgt aaatgaaata ggtgcttgta aaattttcgt gttaataacc
    84301 gaaatattgt aatcactatc tgttgttata taaataggca ggaatgatat accttgattc
    84361 atttcgatta atttaattga agtatgcaca tcattgatag atagaaattg tgctttttca
    84421 taaatattta aaatattatt tttaagtgat gaccaatatt ctggatggtt atcacttatt
    84481 attttgtatt tttcaaataa agatgcctcg gttagaagat gattattctc tttattggga
    84541 gcaatcaata caattttacc ttcgcatact ttttcagaat gaacttctct tagtttaggt
    84601 tgatttctgc taatcccgat gtcatacgta tgattattaa tatctttttc aatattttca
    84661 tttttgacat ggagagaaac atcaataaac ggatgctcgt taaagaaaga ttttaaaaat
    84721 ttgggcataa tgaatgtcgc gatatatgaa gacacgacaa catttaattt cgattgaaac
    84781 atcgtctttt taagttggat atgcttgatg ccactttcat attgttcaat aaaactttgc
    84841 gcaattggaa gaaatgtatg accatcttca gtcaagataa tttgattttt ataagtttca
    84901 aatagtttca cattgagatg ctgttctaaa tttttaattt gcttatgtat agaaggtata
    84961 gtgagattaa tttcttcact agctaatcga tagtttaacg tcttcgctaa aatgacaaat
    85021 gtatagtacc aatccaaatt catgaactta cctctttcaa aaaagttaat aattcattag
    85081 ataatattta atttttattg cataaaaata atattaatat tatatcagag gttaccgagg
    85141 gggtgaagta atatgattcg aattcaagat aatacaataa gggatggtat gcaacaaagt
    85201 aatgttcgta aaagcattat tgtaaaaaaa gaagtgttac aagaaataaa taagataagc
    85261 ataaattctg tggaagttgg catgtgcaca acttttgagg atgaatataa tattcatcaa
    85321 taccgagaaa ttttaaataa tgataaagaa atagtagtct taactcggct agatgaaaat
    85381 gaaattaata aaattctaaa tttaaaaata cataacctag cagtaaaaat acttttacca
    85441 atatctgatt tacacataaa agaaaaactt aacttcacaa gtgagtatta caatgaacga
    85501 attaataagt gtttaaatat gataaaggta aatcaagtag caattgatat ttgttttgaa
    85561 gatgctacaa gatgttcatt agaaaaatta tgtgaatata tggaaatgat ttcaaaattt
    85621 ccaataagaa cagttacttt tgctgatact gttggatgtt caactccatt tgaatatgga
    85681 aatattttta aggaatttgt aaaaaaatat ccaaatataa ctttttctgc tcattgtcat
    85741 aatgatcttg gattggctac tgccaacaca tttgctgcta ttttaaatgg tgcgcagcaa
    85801 atcgagacaa cttttttagg aattggtgaa agagcaggta atgcctcaat tgaagagata
    85861 atagcaattt taacaaaaaa gcaaatagta atgacttcat tgaatttacc agatatttat
    85921 aaaactagca tgaatataag taaaatactt gatattcgat tagctgaaaa taaacctgtt
    85981 atcggaaaaa atatatttaa acatgaatca ggcattcatc aagatggcac taataaaaat
    86041 ataagtatgt accagtatat attacctagt gatttaggat taaaaaattc aaaagcagtg
    86101 caatttccaa taagtaatat ttcgagtaag aaaattttga aaaataaatt taaatcaatt
    86161 gtgcatccta aagatattga ggaaaacata tcattttata aactcataaa caaattcata
    86221 cctgaggttg tacctgaaga tacagcagac ttacttcagg taataaaagg gaggagtaaa
    86281 gatggaaatt ttaaatgaat ctgttgaaag ctttgaaaaa ttatacttac aactacaaaa
    86341 tagttacccc ataattgttc ccacggatac aaattataat ttatgcagct tgcctaacaa
    86401 taaaatttgc attgatagaa tatttaaata taaaaagcgt tcaaaagaca aaccgttatc
    86461 tttatttatt gatgaaccag aagactggaa attatatgga gaaaataaaa atgtagaatt
    86521 agtagataaa ctggttaata tattttggcc aggtccatta aatattattt tgaaaaataa
    86581 aacgaattat aactacatgc ttaataattc agatagtatt gcgattggat gtgttcaaaa
    86641 taaaacaatg agaaatctaa tttcctacat tcaatcacca attgctatca cttcagcgaa
    86701 tatttcagga actgctgatg atatattgat aactgaaaat gaagcaatta aacatatggg
    86761 gaataatgtt aattatatgc ttaggagtaa aaataaaagt aaatataaat catcaagtac
    86821 gattattaaa gtgacgggga ataaaattga actcttaaga gaaggggata taaaattcga
    86881 agaaataaaa gcaaaactag gttcaggtat tcaatatgaa taaattaata cttggaattt
    86941 atttatatcg aattttgtca agagcttact tctatttgcc atttttatta atttattttt
    87001 tagcacaaaa ctattctata atgcagttag aaatactaat ggcgacatat ggagttgcag
    87061 cttttttgtt cggtttatat aaagagaaaa tatttagaat ttatcagata aaagatgctt
    87121 ataaattaat tgtgagtgag gtatttaaaa taataggctt aatattatta ttgtatccaa
    87181 gccattttta tattttatta gtagcccaac tgttattagg tttgagttat tcaataatgg
    87241 ctggagtaga tacttctatt attaaaatga atataaaaaa tcataaactt atacaaaata
    87301 aatctaatgg ttatatgttt ttatcattat taatttcagg aattattggg agttaccttt
    87361 atggaattaa tataaaatgg ccgatttata tgacaggttt attttcgatt ttaacaattt
    87421 tagttattct actcacattg gttgaaaacg ttgattgtaa tat
//
LOCUS       DAPSKH010000004        83584 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPSKH010000004 DAPSKH010000000
VERSION     DAPSKH010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 83584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83584
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.004"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(769..867)
                     /locus_tag="RPH49_000317"
     CDS             complement(769..867)
                     /locus_tag="RPH49_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123513.1"
                     /translation="MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG"
     gene            952..2340
                     /locus_tag="RPH49_000318"
     CDS             952..2340
                     /locus_tag="RPH49_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDY5123514.1"
                     /translation="MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVF
                     GVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKF
                     AKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTA
                     HTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRA
                     IDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYI
                     IHLIILSLLGISPIRYIKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFA
                     ATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGA
                     TFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDT
                     FESNDNAALTSH"
     gene            complement(2420..3175)
                     /gene="nfsA"
                     /locus_tag="RPH49_000319"
     CDS             complement(2420..3175)
                     /gene="nfsA"
                     /locus_tag="RPH49_000319"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NADPH nitroreductase"
                     /protein_id="HDY5123515.1"
                     /translation="MSDHVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFL
                     QAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYG
                     STEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPIFG
                     MAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGN
                     RKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR"
     gene            3667..4236
                     /gene="ahpC"
                     /locus_tag="RPH49_000320"
     CDS             3667..4236
                     /gene="ahpC"
                     /locus_tag="RPH49_000320"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDY5123516.1"
                     /translation="MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPAD
                     FSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDP
                     SQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYV
                     RKNPGEVCPAKWEEGAKTLQPGLDLVGKI"
     gene            4252..5775
                     /gene="ahpF"
                     /locus_tag="RPH49_000321"
     CDS             4252..5775
                     /gene="ahpF"
                     /locus_tag="RPH49_000321"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDY5123517.1"
                     /translation="MLNADLKQQLKQLLELMEGNVEFVASLGSDDKSKELKELLTEIS
                     DMSPRLSLSEKSLKRTPSFSVNRPGEETGITFAGIPLGHEFNSLVLAILQVSGRAPKE
                     KQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREE
                     SENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASG
                     SAAIYTARKGLRTSIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDID
                     AMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAF
                     CPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRS
                     LSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDA
                     VELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN"
     gene            5890..7512
                     /locus_tag="RPH49_000322"
     CDS             5890..7512
                     /locus_tag="RPH49_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123518.1"
                     /translation="MLDAHFIYPGKLQNACEYFNLPNDKEGFEVTMHALRPENLHKIY
                     HDMNKTEQKFIETLISKGNPVTIINSHEVNILKLTNHLGFVIQINEDTFFVNNLFLSY
                     INSEVLNSAYGEFETLDTKDHMHLNDEIFRVRQHTRLNDVTMEQALLLKTNDELKAIC
                     RQYGIKGFSNKNKQNLVKLIMTAFFNNNHIIEQVFSNASLFEFSILTGILESDDNYRL
                     NNELITFENIHLMNPGTFLITHFYYYYDFGYDCLILPNDVRKHIENYLNQIADGDIKE
                     AINEFIDEQTIKHSLADFENAIELSMMDDEVHFDILYDEDDDFEDFGTTDSLRNDAIT
                     ELISEIKKGLIDKKDILPLRIILGSVNLYGILSTNHLLYLTQRFYDATFSKEELQYSL
                     DTLAGTELYYIEDDFVFHPVLFDVVESEASGINISDEGYYVPASVEELIYYDRHHYLK
                     SDSEIKAFTSYLRKQINMKNDIEKEKYVNEIIMLLRTIPTSKLIQPIMQLFIDKAILN
                     NVQNDALLIEKATHARNHLRLWSLQGHRDIPN"
     gene            7585..8211
                     /locus_tag="RPH49_000323"
     CDS             7585..8211
                     /locus_tag="RPH49_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NDxxF motif lipoprotein"
                     /protein_id="HDY5123519.1"
                     /translation="MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKK
                     LETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTE
                     KQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDI
                     EKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK"
     gene            8466..8849
                     /locus_tag="RPH49_000324"
     CDS             8466..8849
                     /locus_tag="RPH49_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123520.1"
                     /translation="MKVRITFIILAILSTIVCLFLAAMHPTGPNTVTFEQPYLFTLNI
                     IIMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSFTQFTPFTLASFIT
                     SIILFASTIITLAIGGKSVDKNDSL"
     gene            complement(8915..9496)
                     /locus_tag="RPH49_000325"
     CDS             complement(8915..9496)
                     /locus_tag="RPH49_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDY5123521.1"
                     /translation="MTIYLVRHGESQSNYDNKHFRSYFCGQLDVPLTDFGKKSADDLC
                     DYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISAN
                     PKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAH
                     QVVIRCLMVYFNNVSREEAVDLKVENCKPYIIE"
     gene            9674..9882
                     /locus_tag="RPH49_000326"
                     /pseudo
     CDS             9674..9882
                     /locus_tag="RPH49_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9921..10175)
                     /locus_tag="RPH49_000327"
     CDS             complement(9921..10175)
                     /locus_tag="RPH49_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDY5123522.1"
                     /translation="MFGFIGMLIVGGLIGWAAGAIMGKDIPGGILGNIIAGIIGSWLG
                     GTLLGHWGPELGSIYILPALIGSIILIALVTLILRAVRKK"
     gene            10469..10732
                     /locus_tag="RPH49_000328"
     CDS             10469..10732
                     /locus_tag="RPH49_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5123523.1"
                     /translation="MNMHILYNLRTKHNLEIDELAQQLNEKYGTKYEAHQIWEWENHH
                     HEPKFKDAMHLADFFDAPYEMFLESKVKEYQKHLEEVDIRMDK"
     gene            complement(10871..11443)
                     /locus_tag="RPH49_000329"
     CDS             complement(10871..11443)
                     /locus_tag="RPH49_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDY5123524.1"
                     /translation="MKLKSLAVLSMSAVVLTACGNDTPKDETKSTESNTNQDTNTTKD
                     VIALKDVKTSPEDAVKKAEETYKGQKLKGISFENSNGEWAYKVTQQKSGEESEVLVAD
                     KNKKVINKKTEKEDTVNENDNFKYSDAIDYKKAIKEGQKEFDGDIKEWSLEKDDGKLV
                     YNIDLKKGNKKQEVTVDAKNGKVLKSEQDH"
     gene            complement(11624..11923)
                     /locus_tag="RPH49_000330"
                     /pseudo
     CDS             complement(11624..11923)
                     /locus_tag="RPH49_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498944.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
     gene            complement(12301..12912)
                     /locus_tag="RPH49_000331"
     CDS             complement(12301..12912)
                     /locus_tag="RPH49_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDY5123525.1"
                     /translation="MFKKHHSKNSILLKSILSLGIIYSGSFGIYSKAGASTQNSSSLQ
                     DKQFQKVEEVPNNSEKALVKKLYDRYSKNTINGKSNKSRNWVYSERPLNENQVRIHLE
                     GTYTVADRVYTPKRNITLNKEVVTLKELDHIIRFAHISYGLYMGEHLPKGNIVINTKD
                     GGKYTLESHKELQKDRENVKINTADIKNVTFDLVKSVNDIEQV"
     gene            13219..13841
                     /locus_tag="RPH49_000332"
                     /pseudo
     CDS             13219..13841
                     /locus_tag="RPH49_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015977853.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            13880..14818
                     /locus_tag="RPH49_000333"
     CDS             13880..14818
                     /locus_tag="RPH49_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Abi family protein"
                     /protein_id="HDY5123526.1"
                     /translation="MLNFDEQIAKLKQMNIFFNIIDTEKANEILRKNNYFFKLAYFRK
                     NFEKKNGGYFIEFAYLSDLATIDMKLRYTMLHLTLDIEHSLKCLVLKLITENNQEDGY
                     KIIDEFLCIDKSYNNSNFDTNSRTPEEVMETKIKNKNEIFKHMNKRGQLPAKLNKYYQ
                     NPPAWVCIEFMQLGQFVSFLNFYYKKYNDEELRVANILMPLVKNIRNKSAHNQPIIAN
                     LNYDSRSPQYLFEKGNNIGISRNMFGIKNFIDTFATLELHNQVCSNAIIQARYHDLDQ
                     LQKRYKRNESYYNNALAIKRFFIALDKIIDFNRPKV"
     gene            complement(15084..15326)
                     /gene="rpsR"
                     /locus_tag="RPH49_000334"
     CDS             complement(15084..15326)
                     /gene="rpsR"
                     /locus_tag="RPH49_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002484306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDY5123527.1"
                     /translation="MAGGPRRGGRRRKKVCYFTANGITHIDYKDTELLKRFISERGKI
                     LPRRVTGTSAKYQRMLTTAIKRSRHMALLPYVKEEQ"
     gene            complement(15378..15881)
                     /gene="ssb"
                     /locus_tag="RPH49_000335"
     CDS             complement(15378..15881)
                     /gene="ssb"
                     /locus_tag="RPH49_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDY5123528.1"
                     /translation="MLNRVVLVGRLTKDPEYRTTPSGVSVATFTLAVNRTFTNAQGER
                     EADFINCVVFRRQADNVNNYLSKGSLAGVDGRLQSRNYENQEGRRVFVTEVVCDSVQF
                     LEPKNAQQNGGQRQQNEFQDYGQGFGGQQSGQNNSYNNSSNTKQSDNPFANANGPIDI
                     SDDDLPF"
     gene            complement(15902..16198)
                     /locus_tag="RPH49_000336"
     CDS             complement(15902..16198)
                     /locus_tag="RPH49_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001831345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDY5123529.1"
                     /translation="MRTYEVMYIVRPNIEEDAKKALVERFNGILATEGAEVLEAKDWG
                     KRRLAYEINDFKDGFYNIVRVKSDNNKATDEFQRLAKISDDIIRYMVIREDEDK"
     gene            16443..16634
                     /locus_tag="RPH49_000337"
     CDS             16443..16634
                     /locus_tag="RPH49_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123530.1"
                     /translation="MNLNIDWSKDFQEFQEILNSGIHPEWLYCAKANLVLEPAYTGEG
                     KQFFSTQDIINASKIIPFF"
     gene            complement(16720..17817)
                     /gene="ychF"
                     /locus_tag="RPH49_000338"
     CDS             complement(16720..17817)
                     /gene="ychF"
                     /locus_tag="RPH49_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDY5123531.1"
                     /translation="MALTAGVVGLPNVGKSTLFNAITKAGALAANYPFATIDPNVGIV
                     EVPDARLLKLEEMVQPKKTLPTTFEFTDIAGIVKGASKGEGLGNKFLSHIREVDAICQ
                     VVRAFDDDNVTHVAGRVDPIDDIEVINMELVLADLESVEKRLPRIEKLARQKDKTAEM
                     EVRILNTIKEALENGKPARSIDFNEEDQKWVNQAQLLTSKKMLYIANVGEDEIGDDDN
                     DKVKAIREYAAQEDSEVIVISAKIEEEIATLDDEDKEMFLEDLGIEEPGLDRLIRTTY
                     ELLGLSTYFTAGVQEVRAWTFKQGMTAPQCAGIIHTDFERGFIRAEVTSYDDYVQYGG
                     ESGAKEAGRQRLEGKEYIMQDGDIVHFRFNV"
     gene            complement(17829..18032)
                     /locus_tag="RPH49_000339"
     CDS             complement(17829..18032)
                     /locus_tag="RPH49_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDY5123532.1"
                     /translation="MASKYGINDIVEMKKQHACGTNRFKIIRMGADIRIKCENCQRSI
                     MIPRQTFDKKLKKIIVSQDDTQR"
     gene            complement(18062..18943)
                     /locus_tag="RPH49_000340"
     CDS             complement(18062..18943)
                     /locus_tag="RPH49_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDY5123533.1"
                     /translation="MDQVMSIISSLFEPLTKIETYESVATKLAMIIIYIIVALIVIKI
                     LDKMIAQGFKIQNKSKKGNKKRSKTLISLVQNVVKYIVWFIVVTTILSKFGISVEGVI
                     ASAGVVGLAVGFGAQTIVKDVITGFFIIFENQFDVGDYVKINNGGTTVAEGTVKSIGL
                     RSTRINTISGELTILPNSSMGEITNYSITNGTAIVKIPVSVDENIDNVEKKLNKLFTS
                     LRSKYYLFVSDPVVIGIDAFEDTRVILRVSAETIPGEGFSGARIIRKEVQKMFLQEGI
                     KTPQPIMTPFNHSENGV"
     gene            complement(19097..19942)
                     /locus_tag="RPH49_000341"
     CDS             complement(19097..19942)
                     /locus_tag="RPH49_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDY5123534.1"
                     /translation="MSELSKSEDQRITKTKYEQIKQIDISDIKPNPYQPRKTFDENHL
                     NDLADSIKQYGILQPIVLRKTVQGYYIVVGERRFRASKIAGLKYVSAIIKDLTDEDMM
                     ELAVIENLQREDLNAIEEAESYQRLMTDLKITQQEVAKRLSKSRPYIANMLRLLHLPK
                     KIADMVKDGRLTSAHGRTLLAIKDEQQMLRLAKRVVKENWSVRYLENHVNELKNVSSK
                     SETDKVDITKPKFIKQQERQLREQYGAKVDISIKKSVGKISFEFESQDDFVRIIEQLN
                     RKYGK"
     misc_binding    20171..20540
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20604..21707
                     /locus_tag="RPH49_000342"
     CDS             20604..21707
                     /locus_tag="RPH49_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDY5123535.1"
                     /translation="MKDTQLAQITLTDDSTGAIANPIHLSTAYKHPKLGQSTGFDYTR
                     TKNPTRSTFETCFAKLEHGIASFATSSGMSAIQLICNLFKPHDEILVSFDLYGGTFRL
                     FEFYEQQYDIKFKYVDFTDYEQVEKEITDKTVALFIEPISNPQMIAIDVKTYYQLCKA
                     KGLLSIIDNTFLTPYLSTPLAEGADIVLHSATKYIGGHNDVLAGVVTVKDESLAQQLF
                     DFHNMTGATLSPIDSYLLLRGLKTLHLRIERAQSNARKLAKKCQSLQAIDEVLYSGQT
                     GMLSLRLNKAYSVAKLLENLDICIFAESLGGTETLVTFPYTQTHVDMPDAEKDKRGID
                     EYLIRLSLGVENYEDIEHDIIQALDKAQIGEIV"
     gene            21704..22864
                     /locus_tag="RPH49_000343"
     CDS             21704..22864
                     /locus_tag="RPH49_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent transferase"
                     /protein_id="HDY5123536.1"
                     /translation="MTLSKETEVIFDWRRGVEYHSANPPLYDSSTFHQTSLGGDVKYD
                     YARSGNPNRELLEEKLARLEQGKFAFAFASGIAAISAVLLTFKSGDHVILPDDVYGGT
                     FRLTEQILNRFNIEFTTVDTTKIEQIEGAIQSNTKLIYIETPSNPCFKITDIKAVSKI
                     AEKHELLVAVDNTFMTPLGQSPLLLGADIVIHSATKFLSGHSDLIAGAVITNNEAISE
                     ALYLIQNGTGNMLSAQDSWTLAKHLKTFPIRFKQSVENAQKIVSFLIKQDEISEVYYP
                     GLTASHLEQAKNGGAVIGLRLADESKAQQFVDALTLPLVSVSLGGVETILSHPATMSH
                     ATLPEEVRQERGITFGLFRLSVGLEDPDELIADIKYALKEAFNESIPHTIER"
     gene            22833..24674
                     /locus_tag="RPH49_000344"
     CDS             22833..24674
                     /locus_tag="RPH49_000344"
                     /EC_number="1.5.1.20"
                     /EC_number="2.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional homocysteine
                     S-methyltransferase/methylenetetrahydrofolate reductase"
                     /protein_id="HDY5123537.1"
                     /translation="MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVE
                     RIHRSYIEAGADVIQTNTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILG
                     TVGGFRGIKQEDISLQTILYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKK
                     YDIPIIAQLTASNTNYLVNGQAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIEL
                     PEHAYLSCYPNASLLDIENSEFKYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIK
                     FIKESIQTLKPVNDKKVIPIPTKALFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLD
                     TDRFFENIAKLDKANVDAVTLADNSLATVRISNIAAASLIKQYYNIEPLVHITCRDRN
                     LIGLQSHLLGLSLIGVNEILAITGDPSKVGHLPGATNVYDVNSKGLTELALRFNQGIN
                     TDGDALKKRTHFNIAGAFNPNVRKLDGAVKRLEKKIESGMSYFITQPVYSKEKIIEIY
                     HATKHLNKPFFIGIMPIASYKNALFLHNEVPGIKMSDEILQQFEAVKDDKAKTRELSL
                     KLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAAYSKSITAHKEAIL"
     gene            24671..26899
                     /gene="metE"
                     /locus_tag="RPH49_000345"
     CDS             24671..26899
                     /gene="metE"
                     /locus_tag="RPH49_000345"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDY5123538.1"
                     /translation="MTTIKTSNLGFPRLGRKREWKKAIESYWAKKISKEELDQTLTDL
                     HKENLLLQKYYHLDSIPVGDFSLYDHILDTSLLFNIIPERFQGRTIDDDLLFDIARGN
                     KDHVASALIKWFNTNYHYIVPEWDNVEPKVSRNVLLDRFKYAQSLNVNAHPVIVGPIT
                     FVKLSKGGHQTFEEKVKTLLPLYKEVFESLIDAGAEYIQVDEPILVTDDSESYENITR
                     EAYDYFEEAGIAKKLVIQTYFEHAHLKFLSSLPVGGLGLDFVHDNGYNLKQIEAGDFD
                     KSKTLYAGIIDGRNVWASDIEAKKVLIDKLLAHTNELVIQPSSSLLHVPVSLDDETLD
                     TSVGEGLSFATEKLDELDALRRLFNQNDSVKYDKLKARYERFQNQSFKNLDYDFESVR
                     TSRQSPFAQRIEQQQKRLNLPDLPTTTIGSFPQSREVRKYRADWKNKRITDEAYETFL
                     KNEIARWIKIQEDIGLDVLVHGEFERNDMVEFFGEKLQGFLVTKFGWVQSYGSRAVKP
                     PIIYGDVKWTAPLTVDETVYAQSLTDKPVKGMLTGPVTILNWSFERVDLPRKVVQDQI
                     ALAINEEVLALEAAGIKVIQVDEPALREGLPLRSEYHEQYLKDAVLSFKLATSSVRDE
                     TQIHTHMCYSQFGQIIHAIHDLDADVISIETSRSHGDLIKDFEDINYDLGIGLGVYDI
                     HSPRIPTKEEITTAINRSLQQIDRSLFWVNPDCGLKTRKEEEVKDALTVLVNAVKAKR
                     QE"
     gene            26942..27694
                     /locus_tag="RPH49_000346"
     CDS             26942..27694
                     /locus_tag="RPH49_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclase family protein"
                     /protein_id="HDY5123539.1"
                     /translation="MTQYPLWQQLNTLKQATWVDLTHTFDPEIPRFSEFEKGEVSTLF
                     TVKDHGFYVQRWNIVTQYGTHIDAPIHFVENKRYLEDIDLKELVLPLIVLDFSTEVAN
                     NNDFIVTRAHIEAWEKEHGTIEPGTFVALRTDWSKRWPNIETFENKDANGQQHAPGWG
                     LDALKYLIEERRVEAVGHETFDTDASVDVVKNGDLVGERYILGQDKYQVELLTNLDQL
                     PTRGAIIYAISPKPKDAPGFPVRAFAIKPSND"
     gene            complement(27777..28958)
                     /locus_tag="RPH49_000347"
     CDS             complement(27777..28958)
                     /locus_tag="RPH49_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDY5123540.1"
                     /translation="MTRVVLAAAYRTPIGVFGGAFKDVPAYDLGATLIEHIIKETGLN
                     PSEIDEVIIGNVLQAGQGQNPARIAAMKGGLPETVPAFTVNKVCGSGLKSIQLAYQSI
                     VTGENDIVLAGGMENMSQSPMLVNNSRFGFKMGHQSMVDSMVYDGLTDVFNQYHMGIT
                     AENLVEQYGISREEQDTFAVNSQQKAVRAQQNGEFDSEIVPVSIPQRKGEPIVVTKDE
                     GVRENVSVEKLSRLRPAFKKDGTVTAGNASGINDGAAMMLVMSEDKAKELNIEPLAVL
                     DGFGSHGVDPSIMGIAPVGAVEKALKRSKKELSDIDVFELNEAFAAQSLAVDRELKLP
                     PEKVNVKGGAIALGHPIGASGARVLVTLLHQLNDEVETGLTSLCIGGGQAIAAVVSKY
                     K"
     gene            29497..30630
                     /locus_tag="RPH49_000348"
     CDS             29497..30630
                     /locus_tag="RPH49_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low temperature requirement protein A"
                     /protein_id="HDY5123541.1"
                     /translation="MVNALTPKHLAEKRAGFHELFFDLIFVYAIQKIAHVILTTQNGS
                     ISADLFFKYIVMSLFLWLMWSHQTFFTNRFGQVTFKDVSFMMFNMFIMVFLSNSLYPD
                     FEKTFFPFFLCVAIMYLSIGFQYLLHIRTGLDYGDKRTCQAFAAVAFVISFLSFLSLV
                     LPQSIHYIPGFLGVFIAATGLIPFQKYLVLSPVNMMHLVERFSLLTIIIFGEVLVGLA
                     SSSFSIDHFSYIYIFQFMILISLFGVYWIITENYINHKLSSIGFRLSYTHLLINIALG
                     VINAAIVFSNNNKLNDLFEINMMYISVLIFYIGLWLITPYFHNELTNAKYISSSLGIL
                     VVSYIISLIFKGHDQVMIISVSVATFCIMLIYFKNQRLRQSDE"
     gene            complement(31020..31649)
                     /locus_tag="RPH49_000349"
     CDS             complement(31020..31649)
                     /locus_tag="RPH49_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 transporter permease"
                     /protein_id="HDY5123542.1"
                     /translation="MKGMFLSSFYATRKQTYIYFIVAIIAAGYFAVFNPLMSSAMAGV
                     MLITPITDNIKHEKDSRWMYYVSTLPVKRSDYIKSYFAFYLILFGASLMIGLVVTTIV
                     TQSVMIGIMSGLMSFGIIGAYSIIFPLTFKFGAENSNVIMIFASILLLISFVVFFFIY
                     GMVSGASALEFEKISTEGWLVVIVYAVIGIVITSVSYILSIKIFNKQEL"
     gene            complement(31649..32491)
                     /locus_tag="RPH49_000350"
     CDS             complement(31649..32491)
                     /locus_tag="RPH49_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123543.1"
                     /translation="MTTLLNVDSVNKQYKDSDFKLQDASLTISTNETVGLIGKNGSGK
                     STLINILVGNRHKDNGSITFFDEEHAMDDVEYKEHIGIVFDDLRVPNKLTIKDIDKVF
                     QSIYTTWNSQKFFDLIKYFELPLQTKIKTFSRGMRMKIALTIALSHDVKLLILDEATA
                     GMDVSGREEVMELLEDFVAQGGGILISSHISEDIEQLADKLVFMKDGRMILTEQKDIL
                     LAQYGIVTTEDKDVEIPKHLIIASRLSKGKYQILVKDYAEIENAEPLKHIDDATKIIM
                     RGEV"
     gene            complement(32516..33229)
                     /locus_tag="RPH49_000351"
     CDS             complement(32516..33229)
                     /locus_tag="RPH49_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HDY5123544.1"
                     /translation="MKILRYIGYLLLGGLVGGIIGGILGNFDGLGIENLTFATYNNVV
                     VISIVATIIIILVEIIVLMNQRRALKYKRLVDEEVDIDATDQYELLANRYVLNGSILS
                     IIQTIIAFVVLLIFVVGHAEANAILFFLIPFFASAIFNTQFTLFNRRFDDRMPKIADK
                     NYTEKRLEILDEGERHIELIALFKTYAINLSILILAIVVIGLYSITTGVNQSFSLLLI
                     IAIFIYNAFSYLLKRRRFY"
     gene            complement(33226..33429)
                     /locus_tag="RPH49_000352"
     CDS             complement(33226..33429)
                     /locus_tag="RPH49_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5123545.1"
                     /translation="MRNRLKELRARDGLNQTQLAKQAGVSRQTISLIERNNFMPSVLT
                     AIKIARIFNEKVETIFIIEEDEA"
     gene            33670..34059
                     /locus_tag="RPH49_000353"
     CDS             33670..34059
                     /locus_tag="RPH49_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HDY5123546.1"
                     /translation="MAFTLSAIQQAHQQFTGVDFPKLFKAFKDMGMTYNIVNIQDGTA
                     TYVHQSEDDIVTSSIKSNHPVAPRSNQSIVQDVLTRHQQGQTDFETFCDEMAEAGIYK
                     WHIDIQAGTCTYIDLKEQAIISELIPQ"
     gene            34159..34383
                     /locus_tag="RPH49_000354"
     CDS             34159..34383
                     /locus_tag="RPH49_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase TatA/TatE family
                     subunit"
                     /protein_id="HDY5123547.1"
                     /translation="MIIMITNTFILGITGPTSLVVISIIALIIFGPKKLPQFGRAIGS
                     TLKEFKSATEDLDKESHDTPSKESKQQREQ"
     gene            34400..35101
                     /gene="tatC"
                     /locus_tag="RPH49_000355"
     CDS             34400..35101
                     /gene="tatC"
                     /locus_tag="RPH49_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006191819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatC"
                     /protein_id="HDY5123548.1"
                     /translation="MVHFSELRHRLVKILLSFVITVIVVYVSSFWWMTPFITYITRAH
                     VSLHAFSFTEMIQIYVMIIFFIAFCFISPVMFYQLWAFIAPGLHNNESQFIYKYSFFS
                     VLLFCAGVAFAFYVGFPMIIQFALKLSLTLNISPVIGFKAYLVELIRWLFSFGILFQL
                     PILFIGLAKFGLIDTTSLKHYRKYIYFACFVLASIIAPPDITLNILLTLPLILLFEFS
                     MFIVKFTCRGKPPTH"
     gene            complement(35194..36906)
                     /locus_tag="RPH49_000356"
     CDS             complement(35194..36906)
                     /locus_tag="RPH49_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000683714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family iron permease"
                     /protein_id="HDY5123549.1"
                     /translation="MKHYLTKIIAMLITAAMVCSFGLLKSQAAAQQSISDVYSVITDA
                     KSVLSNNSISNDNKQKAIEQVVSAVKKLSLEDNSEGNAVKSDVRKLEDAKANDDQKDT
                     LSQLTKSLIAYEEKLASKDAGSKIKLLQQQVDAKDAAMTKAIKDKNKAELESLNNSLN
                     QIWTSNETVIRNYDANQYGQIEVALLQLRIAIHKSPLDTTKVSHAWTTFKSNIDHVDK
                     KSGTSANDQYHVSQLNDELEKAIKAIDDNQLSDADAALTHFIEIWPYVEGQIQTKDGA
                     LYTKIEDKIPYYQSVLDEHNKAHVKDGLVDLNNQIKEVVGHSYSFVDVMIIFLREGLE
                     VLLIVMTLTTMTRNVKDKKGTASVIGGAIAGLVLSIILAITFVETLGNSGILRESMEA
                     GLGIVAVILMFIVGVWMHKRSNAKRWNDMIKNMYANAISNGNLVLLATIGLISVLREG
                     VEVIIFYMGMIGELATKDFVIGIVLAIVILIVFALLFRFIVRLIPIFYIFRVLSIFIF
                     IMGFKMLGVSIQKLQLLGAMPRHVIEGFPTINWLGFYPSYEPLIAQAAYIMVVAILIF
                     KFKK"
     gene            complement(36887..38115)
                     /gene="efeB"
                     /locus_tag="RPH49_000357"
                     /pseudo
     CDS             complement(36887..38115)
                     /gene="efeB"
                     /locus_tag="RPH49_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
     gene            complement(38112..38966)
                     /locus_tag="RPH49_000358"
     CDS             complement(38112..38966)
                     /locus_tag="RPH49_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123550.1"
                     /translation="MKKLTTLLLASTLLIAACGNDDSKKDDSKTSKKDDGVKAELKQA
                     TKAYDKYTDEQLNEFLKGTEKFVKAIENNDMAQAKALYPKVRMYYERSEPVAEAFGDL
                     DPKIDARLADMKEEKKEKEWSGYHKIEKALYEDKKIDDVTKKDAQQLLKDAKELHAKA
                     DTLDITPKLMLQGSVDLLNEVATSKITGEEEIYSHTDLYDFKANVEGAQKIYDLFKPI
                     LEKKDKKLSDDIQMNFDKVNQLLDKYKDNNGGYESFEKVSKKDRKAFADAVNALGEPL
                     SKMAVITE"
     gene            complement(39231..39776)
                     /locus_tag="RPH49_000359"
     CDS             complement(39231..39776)
                     /locus_tag="RPH49_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123551.1"
                     /translation="MFGMKVNEQIRLKILEAHDTEALFNLINRSRNSLREWLPWVDAT
                     EQPSDTRAFIKRGLLQFADGNGFQCGIWYEGMLVGVIGLHEINHMHRKTSIGYYLDKQ
                     FEGHGIMTQAVEALIKYCFDEIDLNRIEISAAVHNEKSRAIPERLGFTREGMLRDNEL
                     LNGIYSSSYIYSLLKSEYNEG"
     gene            40137..41132
                     /locus_tag="RPH49_000360"
     CDS             40137..41132
                     /locus_tag="RPH49_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDY5123552.1"
                     /translation="MASLKNKHFMIGLSLTFIVALFSFLAAKLPILDKVGALTIAILI
                     AILYRHFRGYPEQYSSGITFSSKYLLRFAIILYGLKLNIFDIIGQGSRLLAIDVGVVI
                     FSIVMMLFVNKLLHGDKNIALLLGVGTGVCGAAAIAAVAPIFKSREKDTAISIGIIAL
                     IGTIFSLIYTAIYAIFSMTTNVYGAWSGVSLHEIAHVVLAGGFGGSDALKIALLGKLG
                     RVFLLIPLTIVLILIMRFRSSESSSKGRISIPYFLIGFVIMALVNTYVTIPSALLNIL
                     NTVSTICLLMAMVALGLNVAFKDLKNRALKPLMTIIITSICLSSLAFIVVHWLYS"
     gene            complement(41191..41757)
                     /locus_tag="RPH49_000361"
     CDS             complement(41191..41757)
                     /locus_tag="RPH49_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDY5123553.1"
                     /translation="MNIVLLSGSTVGSKTRIAMDDLKNELEVINEGHQIELMDLRDLE
                     LEFSVGKNYLDTTGDVYKLTTSLMQADVIFIGFPIFQASIPGALKNVFDLLPVNAFRD
                     KVIGLVATAGSSKHYLIPEMHLKPILSYMKAHTMQTYVFIEEKDFSNQQIVNDDVVFR
                     LKALAQSTMRTAKVQQHVLEEENNQYDF"
     gene            complement(41771..42832)
                     /locus_tag="RPH49_000362"
     CDS             complement(41771..42832)
                     /locus_tag="RPH49_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDY5123554.1"
                     /translation="MAKLEMNKNTPLEFGLYSLGDHLLNPLKGEKVSYEQRINEIIEA
                     SKLADEAGIDVFAVGESHQEHFTTQAHTVVLGAIAQATKHIKVSSSSTIISATDPVRV
                     FEDFATLDLISHGRAEIVAGRASRTGIFDLFGYDLKDYDELFEEKLGLLLELNKTERI
                     TWSGKYRPELRNMKIFPRPIDNTLPIWRAVGGPPASAIKAGKQGVPMMITTLGGPAMN
                     FKGSIDAYRQAATEAGFDASPKSLPVSTASLFYTAETTQDAMREFYPHLNTGMSFIRG
                     VGYPKQQFANSSDYREALMVGSPQQIIEKILYQHELYGHQRFMAQLDFGGVPFENVMK
                     NIELIGNDIIPAIKKHLSK"
     gene            complement(42846..43772)
                     /locus_tag="RPH49_000363"
     CDS             complement(42846..43772)
                     /locus_tag="RPH49_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5123555.1"
                     /translation="MNIVGHHHISMYTKDAKRNKDFYTNVLGLRLVEKSVNQDNPSMY
                     HLFYGDEVGTAGTILSFFEIPNAGHKQPGTETIYRFSLLVPNQAALHYFEKRLDNNGI
                     KSERLYYLGQEGIVFKDEDDLEIILLVNDSFEVPHQWQHNAYSEIPQAYQILGIGPVE
                     LRVRNAARTVEFLENVLGYRKRDNKSFDVLTLAPQGLYSDFVVIEQQGQRERPGRGYI
                     HHIAVNTPQMSDLDAIYKKLQQQPQSNSDIIDRYFFKSLYYRHNSIMYEFATEAPGFT
                     IDTPLEQLGSQLNLPDFLEAEREQIESKLHEI"
     gene            44084..45442
                     /gene="glpT"
                     /locus_tag="RPH49_000364"
     CDS             44084..45442
                     /gene="glpT"
                     /locus_tag="RPH49_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDY5123556.1"
                     /translation="MNFLKPAKHIKPLPENQIDDTYKRLRLQVFLGIFIGYAGYYLLR
                     KNFSLAMPALQEQGFTKAELGFALSAVSIAYGFSKFFMGTVSDRSNARIFLVLGLALT
                     AIVNLLMGFVPFFTSGIGIMFVLLFLNGWFQGMGWPPSGRVLVHWFSVSERGSKTALW
                     NVAHNVGGGIMAPIAAWGITTTAFINFGYLKGFEGVFIYPALLALIIAAISYVLIRDT
                     PQSQGLPPIEIYKNDFATSDKKTLETELTTKEILFKYVLNNKWVWAIAFANIFVYFVR
                     YGVLDWAPVYLSEEKHFDLKASGWAYFLYEWAGIPGTLLCGYISDKLFKGRRGPAGFF
                     FMLGVTVFVLIYWLNPPGNAWLDNVSLIAIGFLIYGPVMLIGLQALDYVPKKAAGTAA
                     GLTGLFGYLFGAVMANIVLGAVVDKFGWDVGFILLTAISVFAMLSFILTWNKVGQETV
                     HH"
     gene            complement(45524..45964)
                     /locus_tag="RPH49_000365"
     CDS             complement(45524..45964)
                     /locus_tag="RPH49_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MepB family protein"
                     /protein_id="HDY5123557.1"
                     /translation="MYKSKILLKYIFSEELDVKDLTEEKYNQDYEALTFSFKEETYQS
                     RLAKKTPTKAGYFVACWTKDENNCNQPYSKEAFADYLMIIVIDEELSGYFLFPRELLV
                     EKGILTTFEHKGKMAFRVYPKWCNQLNKTAGQTQKWQCKYFFEY"
     gene            complement(46067..47422)
                     /gene="mepA"
                     /locus_tag="RPH49_000366"
     CDS             complement(46067..47422)
                     /gene="mepA"
                     /locus_tag="RPH49_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498905.1"
                     /note="MepA (multidrug export protein A), as described
                     originally in Staphylococcus aureus, is a MATE transporter
                     shown to be over-expressed after culturing in the presence
                     of tigecycline, owing to mutation of its repressor MepR,
                     and then to be one of several factors contributing to
                     elevated tigecycline resistance; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MepA"
                     /protein_id="HDY5123558.1"
                     /translation="MKDEQLYYFEKSPVFKAMMHFSLPMMIGTLLSVIYGILNIYFIG
                     FLEDSHMISAISLTLPVFAILMGLGNLFGVGAGTYISRLLGAKDYSKSKFVSSFSIYG
                     GIALGLIVILVTLPFSDQIAAILGARGETLALTSNYLKVMFLSAPFVILFFILEQFAR
                     AIGAPMISMIGMLASVGLNIILDPILIFGFDLNVVGAALGTAISNVAAALFFIVYFMK
                     NSDVVSVNIKLAKPNKEMLSEIFKIGIPAFLMSILMGFTGLVLNLFLAHYGNFAIASY
                     GISFRLVQFPELIIMGLCEGVVPLIAYNFMANKGRMKDVIKTVIMSIGVIFVVCMIAV
                     FTIGHHMVGLFTTDQAIVEMATFILKVTMTSLLLNGIGFLFTGMLQATGQGRGATIMA
                     ILQGAIIIPVLFIMNALFGLTGVIWSLLIAESLCALAAMLIVYLLRDRLTVDTSELIE
                     G"
     gene            complement(47529..47948)
                     /gene="mepR"
                     /locus_tag="RPH49_000367"
     CDS             complement(47529..47948)
                     /gene="mepR"
                     /locus_tag="RPH49_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor MepR"
                     /protein_id="HDY5123559.1"
                     /translation="MEFTYSYLFRMISHEMKQKADQKLEQFDITNEQGHTLGYLYAHQ
                     QDGLTQNDIAKALQRTGPTVSNLLRNLERKKLIYRYVDAQDTRRKNIGLTTSGIKLVE
                     AFTSIFDEMEQTLVSQLSEEENEQMKANLTKMLSSLQ"
     gene            48160..50115
                     /locus_tag="RPH49_000368"
     CDS             48160..50115
                     /locus_tag="RPH49_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDY5123560.1"
                     /translation="MLSYRQIEILYLLIHEQTFIPINTIANQLGVSPRTIQYDIAYIE
                     QYAETYHYQVSRNKAAGIKVTTAHATLLNELEHNLTNQIHFSKDERLTHIALKLFETT
                     DPVSTKQLAQDVNVSRRTIADDIKMIQAQLDQYHLKLNYVHNKGFNIIGEEDYYRKAY
                     AHFIHQYMKQAAPFIEADIFNSESIALVRRAIIKTLNSENYHLVQSAIDGLIYHILIA
                     IQRLNENFSFDIPINEINKWRHTNQYAIASKMIENLERSCNVTFPESEIIFITLHLLG
                     SKMTEHTASSITFEYHDLSQNIHELITCVSQELGIDMSKDNKLHTSLITHIKPAIHRI
                     KYDMLQPNPLRQEVMRRYPQIIEAVSKHISPIEQDAAIRFNEDELTYITIHFASSIER
                     VATHKQSMIKVVLLCGSGIGTSQLLKSKLNHLYPEFHIWDAYSIYQLEESRLLQDNID
                     YVISTVPCEISAVPVIHVDPFINQQSRQKLNQIINDSREQRVMKMATDGKSLADLLPE
                     HRIIINKQPLSIESAIAVAVQPLINDGIVYSNYTAAILKQFEQFGSYMVISPHIALIH
                     AGTDYVQNGVGFALTYFTEGIIFGSKANDPVHLVITLATDHPNAHLKALGQLSECLSS
                     DLYRQDFLDGNIFKIKQHIALTMTKEA"
     gene            50120..50563
                     /locus_tag="RPH49_000369"
     CDS             50120..50563
                     /locus_tag="RPH49_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDY5123561.1"
                     /translation="MSLDILSTTRIIVKEQVNDWTEAITIASQPLLQEQIIEQGYVQA
                     MIDSVNELGPYIVIAPEIAIAHARPNNDVHQVGLSLLKLNQHVAFCDENHYASLIFVL
                     SAIDNHSHLSVLQNLATILGDNQTVQQLLTATNAQDIKNILKEHD"
     gene            50565..50849
                     /locus_tag="RPH49_000370"
     CDS             50565..50849
                     /locus_tag="RPH49_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDY5123562.1"
                     /translation="MKILVVCGHGLGSSFMVEMNAQEALRQLNAPSDIEVEHSDIMTA
                     SPEMADLFICGRDLAENAERLGDVLVLDNILDKAELQQKLSEKLQQLNMI"
     gene            50864..52210
                     /locus_tag="RPH49_000371"
     CDS             50864..52210
                     /locus_tag="RPH49_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDY5123563.1"
                     /translation="MQAILNFIVDILSQPAILVALIAFIGLIVQKKPAATITSGTIKT
                     ILGFLILSAGADVVVRSLEPFGKIFQHAFGVQGIVPNNEAIVSLALKDFGTTAALIMV
                     CGMIVNILIARFTNLKYIFLTGHHTFYMAAFLAIILTVSHIKGWLTIVIGALVLGLIM
                     AVLPALLQPTMRKITGNDQVALGHFGSISYFAAGAVGQLFKGKSKSTEEIKFPKGLSF
                     LRESTISISITMALLYFIACLFAGVSYVHESISDGQNFIVFSLIQGVTFAAGVFIILT
                     GVRLILAEIVPAFKGISEKLVPNSKPALDCPIVFPYAQNAVLIGFFVSFITGVIGMFI
                     LFLFGGVVILPGVVAHFFLGATAAVFGNARGGIKGAVAGAALNGILITFLPLLFLPFL
                     GELGGAATTFSDTDFLAVGIVFGNAVKYMGLFGAILFIIIVGATAILLKGRQKPQQ"
     gene            complement(52304..53329)
                     /locus_tag="RPH49_000372"
     CDS             complement(52304..53329)
                     /locus_tag="RPH49_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde reductase"
                     /protein_id="HDY5123564.1"
                     /translation="MNNKVLVTGGTGFVDMRIISRLLEQGYEVKTTIRDLSKADKVIK
                     TMQDNGISTERLMFVEADLSQDEHWDEAMKDCKYVLSVASPVFFGKTDDAEVMAKPAI
                     EGIQRILRAAEHAGVKRVVMTANFGAVGFSNKDKNSITNESHWTNQDEPGLSVYEKSK
                     LLAEKAAWDFVDNENTTVEFATINPVAIFGPSLDAHVSGSFHLLENLLNGSMKRVPQI
                     PLNVVDVRDVAELHILAMTNEQANGKRFIATADGQINLLEIAKLIKEKRPEIAQKVAT
                     KKLPDFILSLGAKFNHQAKEGKLLLDMNRNVSNERAKTLLGWEPIATQEEAILAAIDS
                     MVKFHLI"
     gene            complement(53645..54667)
                     /locus_tag="RPH49_000373"
     CDS             complement(53645..54667)
                     /locus_tag="RPH49_000373"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDY5123565.1"
                     /translation="MYLIEPIRNGEYITDGAIALAMQVYVNQNIFLDDDILFPYYCDP
                     KVEIGRFQNTAIEVNQDYIDKHSIQVVRRDTGGGAVYVDKGAVNMCCILEQDTSIYGD
                     FQRFYQPAIKALHTLGARDVIQSGRNDLTLNGKKVSGAAMTLMNNRIYGGYSLLLDVN
                     YEAMDKVLKPNRKKIASKGIKSVRARVGHLREALDEKYRGITIEEFKNLMVTQILGID
                     DIKEAKRYELSEADWEAIDELADKKYKNWDWNYGKSPKYEYNRSERLSSGTVDITISV
                     EQNRIADCRIFGDFFGQGDIKDVEQALQGTKMTREDLTHQLKQLDIVYYFGNVTVESL
                     VEMILS"
     gene            complement(54645..55589)
                     /locus_tag="RPH49_000374"
     CDS             complement(54645..55589)
                     /locus_tag="RPH49_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent deacetylase"
                     /protein_id="HDY5123566.1"
                     /translation="MQSSKWNAMSLLMDDKTKQAEVLRTAIDEADAIVIGIGAGMSAS
                     DGFTYVGERFTENFPDFIEKYRFFDMLQASLHPYGSWQEYWAFESRFITLNYLDQPVG
                     QSYLALKSLVEGKQYHIITTNADNAFDVADYDMTHVFHIQGEYILQQCSQHCHAQTYR
                     NDDLIRKMVVAQQDMLIPWEMIPRCPKCDAPMEVNKRKAEVGMVEDAEFHAQLQRYNA
                     FLEQHQDDKVLYLEIGIGFTTPQFVKHPFQRMTRKNENALYMTMNKKAYRIPNSIQER
                     TIHLTDDISTLITTALRNDSTTKNNNIGETEDVLNRTD"
     gene            complement(55579..56379)
                     /locus_tag="RPH49_000375"
     CDS             complement(55579..56379)
                     /locus_tag="RPH49_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-ADP-ribose hydrolase"
                     /protein_id="HDY5123567.1"
                     /translation="METLKSNKARLEYLINDMRRERNDNDVLVMPSSFEDLWELYRGL
                     ANVRPALPVSDEYLAVQDAMLSDLNRQHVTDLKDLKPIKGDNIFVWQGDITTLKIDAI
                     VNAANSRFLGCMQANHDCIDNIIHTKAGVQVRLDCAEIIRQQGRNEGVGKAKITRGYN
                     LPAKYIIHTVGPQIRRLPVSKMNHDLLAKCYLSCLKLADQHSLNHVAFCCISTGVFAF
                     PQDEAAEIAVRTVESYLKETNSTLKVVFNVFTDKDLQLYKEALNRDAE"
     gene            complement(56380..56712)
                     /locus_tag="RPH49_000376"
     CDS             complement(56380..56712)
                     /locus_tag="RPH49_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDY5123568.1"
                     /translation="MKKLANYLWVEKVGDLYVFSMTPELQDDIGTVGYVEFVSPDEVK
                     VDDEIVSIEASKTVIDVQTPLSGTIIERNTKAEEEPTILNSEKPEENWLFKLDDVDKE
                     AFLALPEA"
     gene            complement(56746..57747)
                     /locus_tag="RPH49_000377"
     CDS             complement(56746..57747)
                     /locus_tag="RPH49_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HDY5123569.1"
                     /translation="MVKLSVLDYALIDEGKDAQKALQDSVTLAKLADRLGFKRIWFTE
                     HHNVPAFACSSPELLMMHTLAQTNHIRVGSGGVMLPHYRPYKIAEHFRMMAALYPNRI
                     DLGIGNNPGTTMVKQALDGINPTYDSYDESISLLRDYLTIKDKPSAHTLGVQPHIDHF
                     PEMWLLSSSATSAKIAAELGIGLSVGTFLLPDINAIHAAKDNIDIYKKHFQASTIKMD
                     AKVMASVFVIVADNEAEVAALQHALDVWLLGKLQFAEFEHFPSVDTAQKYKLNDRDKE
                     MIQAHQARIIAGTQEQVRAQLDDFIATFEVDEVLVAPLIPGIEQRCKTLKLLAEIYL"
     gene            complement(57861..57959)
                     /locus_tag="RPH49_000378"
     CDS             complement(57861..57959)
                     /locus_tag="RPH49_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123570.1"
                     /translation="MESIFKIKIELMNVICRSENMNMKKKNTSEKI"
     gene            58055..59254
                     /locus_tag="RPH49_000379"
     CDS             58055..59254
                     /locus_tag="RPH49_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDY5123571.1"
                     /translation="MYRYKPLLQSIHLPNGIKISNRFVLSPMTVNASTKEGYITKADL
                     AYAARRSNSAGMQVTGAAYIEPYGQLFEYGFNIDHDACIPGLTNMASTMKQHGSLAII
                     QLAHAGRFSNQAILNFGKVYGPSPMTLHSPIEHDVIAMSHEKINSIIQQYRDATLRAI
                     KAGFDGVEISIAQRLLIQTFFSTFSNKRTDHYGADSLKNRARLCLEVMCAVQEVIDKE
                     APDNFILGFRATPEETRGSDLGYTIDEFNQLIDWVMDVSNIQYLAIASWGRHIYQNTS
                     RTPGEHFGRPVNQIVYEHLAGRIPLIASGGINSPESALDALQHADMVGMSSPFVTEPD
                     FVHKLAEQRPHDINLEFSMADLEDLAIPHAAFKDIVKMMDYGEGLKKHTRDALRQLEQ
                     NYHDSSS"
     gene            59327..60154
                     /locus_tag="RPH49_000380"
     CDS             59327..60154
                     /locus_tag="RPH49_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5123572.1"
                     /translation="MTEIKDKVITKDAFELPYTIIKAKHQPTKGAIVYIHGGGLMFGK
                     ANDLSPQYIDILTEHYDLIQLSYRLLPEVSLDCIIEDVYASFDAIQSQYSNCPIFTFG
                     RSSGAYLSLLIARDRDIDGVIDFYGYSRINTEPFKTTNSYYAKIAQSVNETMIAQLTS
                     PTPVVQDQIAQRFLIYVYARGTGKWINMINIADYTDSKYNIAPDELKTLPPVFIAHCN
                     GDYDVPVEESEHIMNHVPHSTSERVNKNEHDFDRRPNDEAITIYRKVVDFLNAITMV"
     gene            complement(60396..62471)
                     /gene="lip2"
                     /locus_tag="RPH49_000381"
     CDS             complement(60396..62471)
                     /gene="lip2"
                     /locus_tag="RPH49_000381"
                     /EC_number="3.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK domain-containing triacylglycerol lipase
                     Lip2/Geh"
                     /protein_id="HDY5123573.1"
                     /translation="MLRGQEERKYSIRKYSIGVVSVLAATMFIVSSHEAQASEKTPTS
                     NAAAQKETLNQPGEQGNTITSHQMQSGKQLDDMHKENGKSGTVTEGKDTLQSSKHQST
                     QNSKTIRTQNDNQVKQDSERQGSKQSHQNNAINKTERQNDQVQNTHHAERNGSQSTTS
                     QSNDVDKSQPSIPAQKVLPHHDKAAPTSTTPPSNDKTAPKSTKAQDATTDKHPNQQDT
                     HQPAHQIIDATQDDTVRQSEQKPQVGDLSKHIDGQNSSEKPTDKNTDNKQLIKDALQA
                     PKTRSTTNAAADAKKIRPLKANQVQPLNKYPVVFVHGFLGLVGDNAPALYPNYWGGNK
                     FKVIEELRKQGYNVHQASVSAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGK
                     TYKGIMPNWEPGKKVHLVGHSMGGQTIRLMEEFLRNGNKEEIAYHKAHGGEISPLFTG
                     GHNNMVASITTLATPHNGSQAADKFGNTEAVRKIMFALNRFMGNKYSNIDLGLTQWGF
                     KQLPNESYIDYIKRVSKSKIWTSDDNAAYDLTLDGSAKLNNMTSMNPNITYTTYTGVS
                     SHTGPLGYENPDLGTFFLMDTTSRIIGHDAREEWRKNDGVVPVISSLHPSNQPFINVT
                     NDEPATRRGIWQVKPIIQGWDHVDFIGVDFLDFKRKGAELANFYTGIINDLLRVEATE
                     GKGTQLKAS"
     gene            62889..64202
                     /locus_tag="RPH49_000382"
     CDS             62889..64202
                     /locus_tag="RPH49_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HDY5123574.1"
                     /translation="MNQYHSNAQQPSAWRFFVYSLVGILCFFIPFTINGNNTIFVDHV
                     HLAIRSIIGPLMPYVALIMILIGTALPIVRRTFMTSITNLVITLFKVAGAMIGIMYVF
                     KIGPSILFKANYGPFLFEKLMMPLSILIPVGAIALSLLVGYGLLEFVGVYMEPIMRPI
                     FKTPGKSAVDAVASFVGRYSLGLLITNRVYKQGMYNKREATIIATGFSTVSATFMIIV
                     AKTLGLMPHWNLYFWITLVITFVVTAITAWLPPITNESTEYYNGQEGEQEVAIEGSRL
                     KTAYAEAMKQNALTPSLVKNVWDNLKDGLEMTVGILPSILSIGFLGLIVANYTPFIDW
                     LGYIFYPFIYIFPIADQALLAKASAISIVEMFLPSLLVTKAAMSTKFVVGVVSVSAII
                     FFSALVPCILATEIKIPVWKLIIIWFLRVALSLLITIPVALLIFG"
     gene            complement(64333..65001)
                     /locus_tag="RPH49_000383"
     CDS             complement(64333..65001)
                     /locus_tag="RPH49_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDY5123575.1"
                     /translation="MLPHGLIVSCQALPDEPLHSSFIMSKMALAAYEGGAVGIRANTK
                     EDILAIKETVDLPVIGIVKRDYDHSDVFITATSKEVDELIESQCEVIALDATLQQRPK
                     ETLDELVSYIRTHAPNVEIMADIATVEEAKNAARLGFDYIGTTLHGYTSYTQGQLLYQ
                     NDFQFLKDVLQSVDAKVIAEGNVITPDMYKRVMDLGVHCSVVGGAITRPKEITKRFVQ
                     VMED"
     gene            65141..65941
                     /locus_tag="RPH49_000384"
     CDS             65141..65941
                     /locus_tag="RPH49_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDY5123576.1"
                     /translation="MKFENRVQRYQHLFTKTDKRIVNYIRQNGYSDAFSTINSLAHAI
                     GTSPATMTRFSHKLDYENFQDLKFNIQQEMTETVIENSPIIQRIHKYHQQIIQQTGEF
                     IDNDIIQTFIDKLQSSRHILFAGLGSSGLSATEFYYRMIRMGLKGNVTTDSHLMKISA
                     SLLSHSDMFIAMSNSGNTSELISAAEVAKSHGAYVVAITNFEGSKLTDCADLVLLTTD
                     QSRNTDHQFINTQIATLFLIDIVSYHLLENTNLSQTYQHTKSIILDNK"
     gene            complement(66218..67078)
                     /locus_tag="RPH49_000385"
     CDS             complement(66218..67078)
                     /locus_tag="RPH49_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDY5123577.1"
                     /translation="MYYIAIDIGGTQIKSAVIDKQLNMFDYQQIPTPDNKSELITDKV
                     YEIVTGYMKQYQLIQPVIGISSAGVVDEQKSEIVYAGPTIPNYKGTNFKRLLKSLSPY
                     VKVKNDVNAALLGELKLHQYQAERIFCMTLGTGIGGAYKNNQSHIDNGELHKANEVGY
                     LLYRPTENTTFEQRAATSALKKRMIDGGFTRSTHVPVLFEAAEEGDDIAKQILNEWAE
                     DVAEGIAQIQVMYDPGLILIGGGISEQGDNLIKYIEPKVAHYLPKDYVYAPIQTTKSK
                     NDAALYGCLQ"
     gene            67236..68117
                     /locus_tag="RPH49_000386"
     CDS             67236..68117
                     /locus_tag="RPH49_000386"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDY5123578.1"
                     /translation="MNKDLKGLYAALLVPFDENGQVNEQGLKQIAQNAIETEELDGLY
                     VNGSSGENFLLNTEQKKQVFKVAKEAVGDKVKLIAQVGSLDLNEAIELGKYATELGYD
                     ALSAVTPFYYPFTFEEIRDYYFDIIEATQNNMIIYAIPDLTGVNISIEQFSELFNHEK
                     IVGVKYTAPNFFLLERIRKAFPDKLILSGFDEMLVQATISGVDGAIGSTYNVNGRRAR
                     KIFDLARQGQIQEAYQLQHDSNDIIETVLSMGIYPTLKEILRHRGIDAGLPKRPFKPF
                     NEAHRQTLDQLIAKYDL"
     gene            68157..69689
                     /locus_tag="RPH49_000387"
     CDS             68157..69689
                     /locus_tag="RPH49_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HDY5123579.1"
                     /translation="MKEVGFGTLNWVAVIIYLLAMLFIGVYFTKRASQSTNSFFTASG
                     RLPSWVVGFSIYATTLSAITFMSTPEKAFLTDWSYIAGNIAIVAIIPLLIYFYVPFFK
                     KLKVTSAYEYLEARFGPSIRVIGSLLFVVYHLGRVAIVIYLPTLAITSVSDMNPYIVA
                     SLVGLLCILYTFLGGFEGVVWSDFIQGVILLGGALVIIILGVMNIKGGFGTVFADAIE
                     HKKLISADNWKLNTAAAAIPIIFLGNIFNNLYQYTASQDVVQRYQASDSLKETNKSLW
                     TNGILALISAPLFYGMGTMLYSFYTHEAVLPKGFNTSSVVPYFILTEMPPFVAGLLIA
                     AIFAAAQSTISSSLNSISACISIDIKQRFFGKGSERHEVNFARFIIIIAGIFGFGMSL
                     YLIASNSNDLWDLFLFVTGLFGVPLAGVFAVGIFTKRTNTFGVICGLILGIIFAYVYN
                     GVGKGNSPFYVSTISFTVAFVFAYILSFIVPSKHKKDITGLTIFEKDKPSTYISKTAT
                     KK"
     gene            complement(69794..71014)
                     /locus_tag="RPH49_000388"
     CDS             complement(69794..71014)
                     /locus_tag="RPH49_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDY5123580.1"
                     /translation="MNILFAITGIAFALFVAFLFSFDRKNIDFKKTLIMIFIQVLIVL
                     FMMNTTIGLTILTALGSFFEGLINVSKAGINFVFGDIQNKNGFTFFLNVLLPLVFISV
                     LIGIFNYIKVLPFIIKYVGIAINKITRMGRLESYFAISTAMFGQPEVYLTIKDIIPRL
                     SRAKLYTIATSGMSAVSMAMLGSYMQMIEPKFVVTAVMLNIFSALIIASVINPYKSDD
                     SDVEIDNLTKSTETKSVNGKTGKPKKVAFFQMIGDSAMDGFKIAVVVAVMLLAFISLM
                     EAINIMFGSVGLNFKQLIGYVFAPIAFLMGIPWSEAVPAGSLMATKLITNEFVAMLDF
                     KNVLGDVSARTQGIISVYLVSFANFGTVGIIVGSIKGISDKQGEKVASFAMRLLLGST
                     LASIISGSIIGLVL"
     gene            complement(71025..71948)
                     /locus_tag="RPH49_000389"
     CDS             complement(71025..71948)
                     /locus_tag="RPH49_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDY5123581.1"
                     /translation="MANLQKYIEYSREVQQARENNQPIVALESTIISHGMPYPQNVEM
                     ATTVEQIIRNNGAIPATIAIIDGKIKIGLESEDLEILATSKDVAKVSRRDLAEVVAMK
                     CVGATTVATTMICAAMAGIQFFVTGGIGGVHKGAEHTMDISADLEELSKTNVTVICAG
                     AKSILDLPKTMEYLETKGVPVIGYQTNELPAFFTRESGVKLTSSVETPERLADIHLTK
                     QQLNLEGGIVVANPIPYEHALSKAYIEAIINEAVVEAENQGIKGKDATPFLLGKIVEK
                     TNGKSLAANIKLVENNAALGAKIAVAVNKLL"
     gene            complement(71923..73041)
                     /locus_tag="RPH49_000390"
     CDS             complement(71923..73041)
                     /locus_tag="RPH49_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDY5123582.1"
                     /translation="MSDSEKEILKRIKDNPFISQRELAEAIGLSRPSVANIISGLIQK
                     EYVMGKAYVLNEDYPIVCIGAANVDRKFYVHKNLVAETSNPVTSTRSIGGVARNIAEN
                     LGRLGETVAFLSASGQDSEWEMIKRLSTPFMNLDHVQQFENASTGSYTALISKEGDMT
                     YGLADMEVFDYITPEFLIKRSHLLKKAKCIIVDLNLGKEALNFLCAYTTKHQIKLVIT
                     TVSSPKMKNMPDSLHAIDWIITNKDETETYLNLKIESTDDLKIAAKRWNDLGVKNVIV
                     TNGVKELIYRSGEEEIIKSVMPSNSVKDVTGAGDSFCAAVVYSWLNGMSTEDILIAGM
                     VNAKKTIETKYTVRQNLDQQQLYHDMEDYKNGKFTKVY"
     gene            complement(73384..74415)
                     /locus_tag="RPH49_000391"
     CDS             complement(73384..74415)
                     /locus_tag="RPH49_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDY5123583.1"
                     /translation="MDLLIGTLFLFLVLVIFTLFTYKAPNGMRAMGALANAAIATFLV
                     EAFNKYVGGEVFGIKFLEELGDAAGGLGGVAAAGLTALAIGVSPVYALVIAAACGGMD
                     LLPGFFAGYMIGYVMKYTEKYVPDGVDLIGSIVILAPLARLIAVLLTPVVNSTLIRIG
                     DIIQSSTNTNPIIMGIILGGIITVVGTAPLSSMALTALLGLTGVPMAIGAMAAFSSAF
                     MNGTLFHRLKLGDRKSTIAVSIEPLSQADIVSANPIPIYITNFFGGAIAGLIIAMSGL
                     INDATGTATPIAGFLVMFGFNHPTTIVIYGVVMAIVGALAGYLGSIVFKKYPIVTKQD
                     MINRGAVDA"
     gene            complement(74623..75300)
                     /locus_tag="RPH49_000392"
     CDS             complement(74623..75300)
                     /locus_tag="RPH49_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123584.1"
                     /translation="MLKFENVTKSFKDGNRNIEAVKDTNFEINKGDIIALVGPSGSGK
                     STFLTMAGALQTPTSGHILINNQDITTMKQKALAKVRMSEIGFILQATNLVPFLTVKQ
                     QFTLLKKKNKNVMSNEDYQQLMSQLGLTSLLNKLPSEISGGQKQRVAIAKALYTNPSI
                     ILADEPTAALDTENAIEVIKILRDQAKKRKKACIIVTHDERLKAYCDRSYHMKDGVLN
                     LENETVE"
     gene            complement(75313..76362)
                     /locus_tag="RPH49_000393"
     CDS             complement(75313..76362)
                     /locus_tag="RPH49_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123585.1"
                     /translation="MFLAWNEIRRNKLKFGLIIGVLTMISYLLFLLSGLANGLINMNK
                     EGIDKWQADAIVLNKDANQTVQQSVFNKKDIENKYKKQATLKQTGEIVSNGHQKDNVL
                     VFGVEKSSFLVPSLIEGHKATKDNEVLADETLKNKGFKIGDTLSLSQSDEKLHIVGFT
                     ESAKYNASPVIFTNDATIAKINPRLTGDKINAVVVRDTNWKDKKLNQELEAVSINDFI
                     ENLPGYKPQNLTLNFMISFLFVISATVIGIFLYVMTLQKTSLFGILKAQGFTNGYLAN
                     VVISQTLILALFGTAFGLLLTGVTGAFLPDAVPVKFDVLTLLVFAIVLMIVSVLGSLF
                     SILTIRKIDPLKAIG"
     gene            complement(76612..77502)
                     /locus_tag="RPH49_000394"
     CDS             complement(76612..77502)
                     /locus_tag="RPH49_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-nucleotidase, lipoprotein e(P4) family"
                     /protein_id="HDY5123586.1"
                     /translation="MNKISKYIAIASLSVAVTVSAPQTTNSTAFAKSSAEVQQTQQAS
                     IPASQKVNLGNQNIMAVAWYQNSAEAKALYLQGYNSAKTQLDKEIKKNKGKHKLAIAL
                     DLDETVLDNSPYQGYASIHNKPFPEGWHEWVQAAKAKPVYGAKEFLKYADKKGVDIYY
                     ISDRDKEKDLKATQKNLKQQGIPQAKKSHILLKGKDDKSKESRRQMVQKDHKLVMLFG
                     DNLLDFTDPKEATAESREALIEKHKDDFGKKYIIFPNPMYGSWEATIYNNNYKASDKA
                     KDKLRKNAIKQFDPKTGEVK"
     gene            78086..79393
                     /gene="brnQ"
                     /locus_tag="RPH49_000395"
     CDS             78086..79393
                     /gene="brnQ"
                     /locus_tag="RPH49_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDY5123587.1"
                     /translation="MKKQVIISGLMLFSLFFGAGNLIFPPMLGHTAGQNMWIGMLGFA
                     LTGILLPFITVIVVAFYDEGVESVGNRIHPWFGFIFAVVIYMSIGAFYGIPRAANVAY
                     EIGTRHILPVHNQWTLIIFAAIFFAIVYWISLNPSKIVDNLGKLLTPLLLLMVALLSI
                     AVIFNPESALSAPKDKYITHPFISGSLEGYFTMDLVAALAFSVVIVNGYKFKGLTDRM
                     KILKYVCFSGLIAAILLGMIYFALAYVGASTAPGNFKDGTDILTYNSLRVFGSFGNIV
                     FGMTVILACLTTCIGLVNACATFTKKHVPKFSYKIFALIFSIIGFLFTTLGLEMILKI
                     AVPLLTLIYPVSIALVLISFANMFSTFRFSWAYRLATVITLIISILQILNSFNLLHGV
                     ILKWFMMLPLADIDLAWLVPFMLFAIIGFIIDVVIRRPKQATT"
     gene            79632..80456
                     /locus_tag="RPH49_000396"
     CDS             79632..80456
                     /locus_tag="RPH49_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDY5123588.1"
                     /translation="MKEKHIKWDKIFYGDDWVNNVVETIRTKDILQSVYLKRYLLRAM
                     MAGFIIGIITVFVLSVKATHEPDLPPGIVNMASAITFSFALVLILFTNSELLTSNFMY
                     FTVGLYYKVIKPTRVLKIFLLCFAGNILGAAILFSFMRFSNVMTPDMLNQLSAVIEHK
                     TLSTGFVSILMKAIFANFFINISLVIAMQIDDVLAKMFVMMFGVTIFAFMGYEHVVYN
                     SCLFMGGLIYQVDTLHFIPAISNIAAAFIGNYIGGGLIIGLFYAYLNDHHQFYKNN"
     gene            complement(80705..81103)
                     /locus_tag="RPH49_000397"
     CDS             complement(80705..81103)
                     /locus_tag="RPH49_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDY5123589.1"
                     /translation="MEKSIKIMTIIGIVVQGLATVFSLLFMVLAASGVMTTDVSTTVN
                     GEVDPVDAETAAAIFTVLFLFLFIFGIISIILGAIGMFKASKNKKMSGILLIIGAVIS
                     GNIITFALWLISGIKLLTNNKPKDEISDLS"
     gene            complement(81253..81627)
                     /locus_tag="RPH49_000398"
     CDS             complement(81253..81627)
                     /locus_tag="RPH49_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4467 domain-containing protein"
                     /protein_id="HDY5123590.1"
                     /translation="MKRILVVFLMLAIVLAGCSNKGEKYQKDIDKVYKKQNQMNKIAS
                     KVQNTIKTDIKQEDSNTHVYKDGKVIVIGIQLYKDREKMYYFAYEIKDGKAEINREID
                     PIKYMKDHKADYEDENVEVEKD"
     gene            complement(82250..82738)
                     /locus_tag="RPH49_000399"
     CDS             complement(82250..82738)
                     /locus_tag="RPH49_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDY5123591.1"
                     /translation="MTFEEKLSQMYNEIAHEISSMIPVEWEKVYVIAYVDDGGGEVIF
                     NYTKPGSDELNYYTYIPREYNVSEKVFYDLWTDLYRLFKKLRNAFKEEGLEPWTSCEF
                     DFARDGKLNVSFDYIDWVNTEFDQLGRENYYMYKKFGVLPETEYEMEEIRAVEKYVKE
                     QE"
     gene            complement(82749..83249)
                     /locus_tag="RPH49_000400"
     CDS             complement(82749..83249)
                     /locus_tag="RPH49_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01741 family protein"
                     /protein_id="HDY5123592.1"
                     /translation="MTFEEKLSEMYNEIANEISSMIPVEWEKVYAIAYVDDQGGEVVF
                     NYTKPGSDELNYYTNISRDYNVSEEIFDDLWMNLYYLFKNLRNLFKEEGLEPWTSCEF
                     DFTRDGKLKVSFDYIDWINTEFDQLGRENYYMYKKFGVLPEMEYEMEEIKEIEQYIKE
                     QDEAEL"
BASE COUNT        26540 a        15665 c        12631 g        28748 t
ORIGIN      
        1 aagactcagt aatatatcta ttatttaaaa actgattttt tataaaccta tagaactgta
       61 atttactttc aaatttaata ctcaattcat aaaacctgaa acaagctgat atactccatt
      121 caatatctac tttgaagaaa gcatatcaaa ctaatttgtt tcaggttttt taattattca
      181 ttatgattaa tattgaattt tgaataaatt tttatagtat gttactttta aatgggatgg
      241 ctcctgtgta ttcctaaata gattcatctt aataaaccca ttcaatttaa atgtttggct
      301 gtgttagtaa atgacgaatc gcacaagggc tcactcatat tcacatttac tacaaacgcc
      361 tttttgctca aacaaaaata tttttttacg atagcttttg aactcccacc tgcacacacg
      421 aacactcaaa agatgctaat tttgattcga cagaattttt tacaacgtgt ttgttcgaag
      481 cgtcttttca aggttgatca tttattatct ttttattcaa taaatatgag gttagcaatt
      541 tttatcaaac cgtcatagcc acatctcgat tcaaggatgc atttgttttc tcatatctta
      601 tctcttatga cagtgcacga tatatatctt ttccaaatat tcatcacttt tttcctgtta
      661 aaatcatttc tattattaac gctgtaatga caacttattt aatttattac atttaatgcc
      721 ctgcttcatt ttcaaatatc aactttaatc gactaggtca taacactatt aacccttttc
      781 acctttctct actaaattca aaacgatttg tttacaaatt cccttatgcc aacggtcgaa
      841 tttcatcatg tttacattta attgcaaatg ccctcttgaa atattttaaa attaatatta
      901 ttcttagcat actagtcgga attatattca aaaatttgag gagtgacgtt catgaatgct
      961 tttcttacac tgattaatat tattgtattg gtgattttca tcgtaatatt gcacatgatg
     1021 gctcgcaaac atatatcttt tgcgaaacgt gtgtttacag ctttaggtat cggcattgta
     1081 tttggcgtgt tattacatct tgtctatgga acacattcga atgttattac atcaacaagt
     1141 gactggttca acattgtcgg acaaggttac gttgcattgt tgcaaatgat tgtgatgcct
     1201 ttaattttca tttctattgt cgctgcattc actaaaattc aaatcggaga aaagtttgct
     1261 aaaattggta gtctcatttt tatcttttta attggcactg tcaccattgc tgcaattgtt
     1321 ggtgttgtgt atgccttggt gtttggttta gacgcatcaa caattaatct tggtaacgct
     1381 gaacaagcac gtggaagcga aattgctaaa caagcgaaag atttaacagc acatacgtta
     1441 ccacaacaaa ttttggaatt attgcctaaa aatccattct tagatttcac tggacaacgt
     1501 gcaacttcca cgattgctgt cgtgatattt gcttcgttta taggatttgc ttatttacgc
     1561 gtagcacgca aacaacctga tcatggtgaa ttgcttaagc gtgcgattga cgctatctat
     1621 tcactagtaa tggcgattgt gacgttcgtc ttacgtttaa cgccatacgg tgtattagca
     1681 attatggcca acacgttatc gacaagtgac tttggcgcca tttggacttt aggaaaattc
     1741 ttaatcgcat cgtacgctgc attaattacg atgtatatca ttcacttaat tattttaagc
     1801 ctgttaggca ttagccctat tcgctatatt aaaaagactt tggaagtatt aatctttgca
     1861 ttcacatcac gctcaagtgc gggcgcctta ccactgaatg tacaaacaca aacaagacgt
     1921 ctaggcgtgc cagaaggtat tgccaatttc gctgcgacat ttggattgtc gattggacaa
     1981 aatggttgtg caggcattta ccctgccatg cttgcaatta tggtcgcacc cgtcgctaat
     2041 gtagaaattg atttacaatt tattgtaacg ttaatcgctg tcgtgattat tagttcattc
     2101 ggcgttgctg gcgtcggtgg cggggctaca tttgcatcca tattggtgtt gtcaacgtta
     2161 aacttgccag tcgctttagc cggcgtgctc atctccgttg aaccattgat tgacatgggt
     2221 agaacagcat taaacgtgaa cgattcaatg ctagctggta caggtaccgc caagttaact
     2281 aaacattggg acaaagatac tttcgaatca aatgataatg ctgcattaac ttcacactaa
     2341 ttcattgcaa gaaatacccg ccccctctag ctatacttat cattttaagc tagagggggc
     2401 gggttatttt ggtatcttgc tatcgctgta ttaagcctga tttttgcaat tgttctaaca
     2461 tatctaatct tgctttgttt cctaggaaca tctcaatttg ctgcgaccat gtttctttgc
     2521 gattcccgtt tgtacgttga tcatagtact cgctgattgt ctggtcgtaa tctgccattt
     2581 gtgcatactg tgtttcctta tcagcatgat acttattatg atggaagaca tggtcaaatg
     2641 gtaagcgtgg cttggctgca ccattttcgt catctgcggg ttcccctact gccataccaa
     2701 atatcgggaa gacatagtca ggtaagtcta aaatttctcg aactcgttca acatcatttc
     2761 ttaatgatcc taaaaagaca atgccatacc ccatatcttc agcagttacc gcaatatttt
     2821 cggcaactaa tgctgcatcg attgcaccta ctagcaaacc ttccgttgaa ccatatgcat
     2881 tttccatatc agtttcagca tgttgatcaa ctaaatgatg acgataataa tcaataacaa
     2941 agacgaataa atagccattt tctacaacat aaggttgtcc agaaacttct cgtaaatttt
     3001 ccttaatctt ctcatcgtcg ataccaataa ttgagtatgc ttgcaggaaa cttgacgtcg
     3061 aagcgctttg tccagcttct accaatttct taacaacgtc ttcacttaaa ggcttattct
     3121 taaattttct aacagaatga tgctttttca caagattata tacatgatct gacacgttac
     3181 ccactcctcg atactttaca gttaattaaa aatcttcata ttgcaattgt acacgtccaa
     3241 acttttttat agcaattatt tgcttataag ttaataattg aacttttaaa aatattgtct
     3301 cgtacttgaa aaatccagtt tctcacgcat taccttcatc catctcgaac aaatattctc
     3361 acaccattat caataaggtt gacttagttg agaatacaaa tcttcttttt ttacattttt
     3421 tacattaaaa tcaagatatt aaatatagac acaacctttt aaatcatcaa ctacaaaatc
     3481 cattatcaaa gcactttata ttatctttct ttattttaaa agtaatcatt cactttacaa
     3541 agttatccag ttgactattc tggatcaaaa tgtaataatg ctaactaaga gattagaatt
     3601 attataatta agcacaatca attgatagtt ctaattcata cttaaattct taggaggaag
     3661 atatttatgt cattaattaa caaagaaatc ttaccattta cagcgcaagc tttcgatcca
     3721 aaaaaagatc aatttaaaga agttacacaa gaagatttaa aaggttcttg gagcgtagta
     3781 tgcttctatc ctgctgactt ctcattcgtt tgtccaactg aattagaaga cttacaaaac
     3841 caatatgaag aattacaaaa attaggcgta aatgtattct cagtatcaac tgatactcac
     3901 ttcgtacaca aagcatggca tgaccattca gatgcaatta gcaaaatcac ttacactatg
     3961 attggtgacc catcacaaac aatcactcgt aattttgatg tattagatga agctactggc
     4021 ttagctcaac gtggtacatt cattatcgac ccagacggtg ttgtacaagc atctgaaatt
     4081 aacgctgacg gaattggacg tgacgctagt acattagctc acaaaatcaa agcagctcaa
     4141 tatgttcgta aaaaccctgg cgaagtatgc ccagctaaat gggaagaagg cgctaaaaca
     4201 ttgcaacctg gtttagattt agtaggtaaa atctaaggag gcattacaac catgcttaat
     4261 gctgatttaa aacaacaact taaacaacta ttagaactaa tggagggcaa cgttgaattc
     4321 gttgccagcc ttggttcaga tgataaatct aaagaactaa aagaattatt aacagaaatt
     4381 tctgatatgt cacctagact ttcactttct gaaaagtctt taaaacgtac accaagtttc
     4441 tcagtcaatc gtcctggtga agaaacaggt ataacatttg caggtattcc attaggtcac
     4501 gagtttaact cacttgtttt agcaatttta caggttagtg gtcgtgcacc taaagaaaaa
     4561 cagtcaatca ttgaccaaat taaaaactta gaaggttcat tccattttga aacattcatt
     4621 agtttaacgt gtcaaaaatg tcctgatgtc gttcaagcac ttaacttaat gagtgtgatc
     4681 aaccctaaca tcacgcattc tatgattgat ggtgcagtgt tccgtgaaga atctgaaaac
     4741 atcatggcag tccctgctgt ctttttaaat ggcgaagaat ttggcaatgg tcgtatgaca
     4801 atccaagata ttctttcgaa actaggcagt acggcagatg catctgagtt tgaaaataaa
     4861 gaaccttatg atgtcttaat cgttggtggt ggtcctgcta gtggtagtgc agcgatttac
     4921 acagcacgta aaggtttacg tactagtata gttgctgatc gtatcggtgg ccaagttaat
     4981 gatactgctg gtattgagaa cttcattact gttaaagaaa caactggttc tgaattttct
     5041 tctaacttag cagcgcacat tgatcaatat gacattgatg caatgacagg cattcgtgct
     5101 acagatatcg aaaagactga cgaagcaatt aaagttacgt tagaaaacgg tgctgtctta
     5161 gaaagtaaaa cagtcattat tgctactggt gcaggttggc gtaagctaaa cattccaggt
     5221 gaagagcaat tgattaataa aggtgttgca ttctgcccgc actgtgacgg acctctattt
     5281 gaaaataaag acgtagcagt tatcggtggc ggtaactctg gggttgaagc agcaattgac
     5341 cttgctggta tcgttaatca tgttacatta ttcgaattcg ctagcgaatt aaaagcagac
     5401 aacgtgttac aagatcgttt acgttcttta tcaaatgttg atatcaaaac aaatgccaaa
     5461 actactgaag ttgtcggaga agaccatgtt acaggtatac gttacgaaga catgagcacc
     5521 ggcgaagaac atctacttaa cttagatggt atctttgttc aaattggttt acttccaaac
     5581 acatcatggt taaaagatgc tgttgaatta aacgaacgtg gtgaaattgt tattgatcgt
     5641 aacaataata ctaacgtacc tggaatattt gctgctggcg atgtcacaga tcagaagaac
     5701 aaacaaatta tcatttcaat gggcgctggt gcaaatgcag cattaaatgc ctttgactat
     5761 attatcagaa actaaagttt tcacagtttc actgacagta tcttacattt gttaagatgc
     5821 tgttattttt ttatcctggc ataaaatcat gttatgataa acttaaaaaa tacaatgagg
     5881 tgtgtaaaaa tgcttgatgc tcattttatc tacccaggaa agttacaaaa tgcatgcgaa
     5941 tattttaatt taccgaacga caaagaagga tttgaagtca cgatgcatgc tttacgtcct
     6001 gaaaatttac ataagattta tcatgatatg aataagacag aacaaaaatt tatagaaaca
     6061 cttatatcta agggtaatcc tgtcacaatt ataaatagcc atgaggttaa tattttaaag
     6121 ctaacaaatc atctaggttt tgttattcaa attaacgaag atacgttctt tgtaaataat
     6181 ttatttttaa gttatatcaa ttcagaggta ctaaatagtg catatggtga attcgaaaca
     6241 ttagatacaa aagaccatat gcatttaaat gatgaaatct ttcgtgtaag acaacatacg
     6301 cgcttaaacg atgtcacaat ggaacaggcc ttactgttaa aaactaatga tgagctaaaa
     6361 gcaatttgca gacagtatgg tatcaaagga ttctcaaata aaaacaagca aaatcttgtt
     6421 aaattgatta tgacagcatt tttcaataat aatcatatca ttgaacaagt gttttctaat
     6481 gcttccctat ttgagtttag tattcttact ggcatactcg aaagtgatga taactatcga
     6541 ttaaacaatg aactaattac atttgaaaac attcatttga tgaatcctgg cacattttta
     6601 attactcatt tctattatta ttatgacttc gggtatgatt gtctcatttt accaaatgac
     6661 gtgcgtaaac atattgaaaa ttacctgaat caaatcgctg atggcgatat aaaagaggct
     6721 atcaatgaat ttattgatga gcaaacgatt aagcatagtt tagcagattt tgaaaatgcg
     6781 atagaattat caatgatgga tgacgaagtt cacttcgata tactatatga tgaagatgat
     6841 gactttgaag attttggtac aaccgatagt ttaagaaatg atgcaatcac tgaattgatt
     6901 tctgagatta agaaaggatt aatagataaa aaagatattt tacctcttcg tattatactt
     6961 ggttctgtaa acttgtatgg tattttatca actaatcatc tactatatct cacacaaaga
     7021 ttttatgacg ctacttttag taaagaagag ttgcaatata gcttagatac tttagctggt
     7081 actgagctat attatattga agatgacttc gtgtttcacc ctgtgttatt tgatgttgtc
     7141 gagtctgagg cgtcaggcat taatatttct gatgaagggt actatgtacc agcttctgtt
     7201 gaggaattaa tctattatga tagacaccac tatttgaaat ctgattcaga aattaaagcg
     7261 ttcacaagtt atctacgcaa acaaatcaat atgaaaaatg atattgagaa ggaaaaatat
     7321 gtgaatgaaa tcattatgct tttacgtaca atacctacat ctaaattgat acaaccaatt
     7381 atgcagttat ttatagataa agctatcctt aacaacgtcc aaaatgatgc attattgata
     7441 gaaaaagcaa ctcatgcacg taatcattta cgtctatggt cattgcaagg tcatcgtgac
     7501 attccaaact aattcaatgt tactctatta aacatgaata cacatttttt caattaaaga
     7561 taaaccaagg agttatatta cattatgaaa aagagattac tactaagtac atttttagca
     7621 tctgcattaa ttcttacagg ttgcgcgtcc gatcaatctg ataacgaaga tcatcacaca
     7681 agtactggca tccatgcacc taaaagcgct aaaaaattag aaacaaaaga tatctttaac
     7741 tcagataaga aaaatagtga tattagtgat gcagaaatga agcaagctat agaaaagtat
     7801 ttgtctgtaa atagcgatat acttgataac aaatatataa tgcaacataa actagataaa
     7861 caaattgata gtcaaacaaa agtgactgaa aaacaagcag aaacacttag tcacttatct
     7921 aacttagctg taaaaaatga tttgcatttc aagaaatttg tcactgaaaa caatattcct
     7981 aaagaatata agaaacccgt tgaattaatg atgaattact tcaaagcttt aaatagtaca
     8041 atcgccaatg ttgatgaaga tattgaaaag cttagctatc aaccgcaaaa taaaatcaat
     8101 gtagtcgacg tgccaacaaa atatgccggt gatgttaata aaaagcaaca agataaaatt
     8161 aaagatttct taaaatctaa aggtatcaag agtgatgtta tcgataaata actgaatgcc
     8221 atcattgcga catgtaacac atcattacat gtgctttaac tcatggcaat tctttatcct
     8281 taaaagtgac taatcaattt agctaaagtc atcatttggg catcaagcag catattactg
     8341 tttgatgctt ttttaattgc cttaaattct ctatccatcc taaaatcccc attagttgac
     8401 gcatttgact atatctctaa cgtatttcat aattatattg actctataaa caaaggatgg
     8461 tcatgatgaa agttcgaatt acttttatta ttttagcaat tttatcaacg attgtttgct
     8521 tgttcttagc agcaatgcat ccaacaggac caaacacagt aacttttgaa cagccatatt
     8581 tattcaccct caacatcatt ataatggtat tagtcgcatt accttcactt gttttagcta
     8641 tatatgatta tatgagtttt agaatttctt ctgctatttt acaatttcta ggggctatct
     8701 cttggttctt tttatcattg atattatcgt tcacacaatt tacacctttt acattagcgt
     8761 catttataac ttcaattatt ttgttcgcaa gcacaattat cacattagct attggtggta
     8821 agtctgttga taagaatgat tccctttaaa ttccaaatac aaaaaaggtt ctgaaggccg
     8881 ctataaaaca cagcttttca gaacctctat acttctattc aatgatatat ggtttgcaat
     8941 tttcaacttt taaatccaca gcttcttccc gtgaaacgtt attaaaataa accattaaac
     9001 aacgaatgac aacttgatgt gcaacaatga cgatatcatc tttttgtgta tcttcattga
     9061 caacatgatt cataaaatgt tcgacgcgtt gatatacatc ttcataactt tctccttcag
     9121 gcgctttttg tgaaaaacta tgacgaaagt ctttaaagtt tggatcattg aaatattttt
     9181 catatttcgg attcgcactg atttcatctt tatattcacc ctcaaatacg ccaagcgaac
     9241 gttctcttaa tagaggcgta gtcgttgatg caatgtcata tggaaaaata tgttcaaacg
     9301 tttgctgtgt ccttaataag tctgaaacat atacatgttt aatctgtttc tctttaaaat
     9361 aatcacataa atcgtctgca cttttcttac caaaatccgt taacggcaca tctaattgtc
     9421 cacaaaaata agatcgaaaa tgtttattat cataattcga ttgtgattcg ccatgtctaa
     9481 ctaaataaat cgtcataata ttactcctta cattatgtat ttcatatcta ccataacact
     9541 ttgactacta attcaatatc aatcttaata ttctattcta aaaaaagaat taattcatat
     9601 tttaaattaa tgactctaaa aatagtattg tctttaatca agtgatgtgt tactatatgg
     9661 gtgtagttct taaatgacta cacagtcttt tatattcatg aacataatac tcctggatgg
     9721 cgcaacccaa cgtcatcctt ttttatttgt caaatactcg cttttttatt tccaaccttt
     9781 cctcatgtta atttattact ttttaatcct atcttaccta cattttcaaa tattataata
     9841 catattgacc attttcacgc aaataaaaaa gatgacaact gaatgccatc ttgatttcca
     9901 ttcaacctaa gttgaatatt ttatttttta cgcacagctc ttaaaattag cgttaccagt
     9961 gcaattaaga taattgaacc aattaaagct ggtaagatgt aaatgcttcc tagttcagga
    10021 ccccaatgtc ctaataatgt tccacctaac catgatccaa taatacctgc gataatatta
    10081 cctaaaatac cacctgggat atctttaccc ataatagcac cagcagccca tccaattaag
    10141 ccaccgacaa ttaacattcc aataaatcca aacataattt tcagtctcct ttttctattt
    10201 attttgcgtt attctaagta gtacccgtta ttagactttc taaaacaaat tcaaattatt
    10261 tttatctaaa tatttttcaa agtagtaatt gaatatcaat tttattcaat gtagctatcg
    10321 ttatttaaag tctctgtacc ggcaatatca tatacattat tttttctggc gaattcatag
    10381 cttgattatt ttatgttata ggactagaat atacacatat tattagagca tctttgaatt
    10441 ttaaatcaag aagcgaggtt aatgaacaat gaatatgcat attttatata acttacgaac
    10501 taaacataat ttagaaattg acgaattagc acaacaatta aatgagaaat atggtactaa
    10561 atatgaagca caccaaattt gggaatggga gaatcatcac catgaaccta aatttaaaga
    10621 tgccatgcat ttagctgact tctttgatgc accatatgaa atgtttttag aaagtaaggt
    10681 taaagaatat cagaaacatt tagaagaagt cgatattcgc atggataagt agatgcaatt
    10741 aaaccctcac aacacgttag gcatatatcc tttcaaatct atactggata tatcacattg
    10801 cgttgtgagg gtatttttaa taattaatat gaattaagac atgttgctat cgttagtgtt
    10861 acgacatatt ttagtgatct tgctcactct ttaatacttt accgttttta gcatcaacag
    10921 taacttcttg ttttttatta ccttttttca aatcgatatt gtaaacaagt ttaccatcat
    10981 ctttttcaag tgaccattct ttaatatcac catcaaattc tttttgtcct tctttaatgg
    11041 cttttttgta atctatagca tcgctatatt taaagttatc attttcattc actgtatctt
    11101 ctttttcagt ctttttgtta atcacttttt tatttttatc agcaacaagt acttctgact
    11161 cttcaccaga tttttgttgc gtcactttat aagcccattc accattagaa ttttcaaatg
    11221 aaattccttt caacttttgg cctttgtaag tttcttcagc ttttttcaca gcatcttctg
    11281 ggcttgtttt aacatctttt aatgcaataa catcttttgt tgtattagtg tcttgattag
    11341 tatttgactc tgttgatttt gtttcatctt ttggagtatc attgccacat gcagtaagca
    11401 ccaccgctga cattgataac actgctaatg attttaattt cataatatca ctctctcttc
    11461 cttttttaga aactcataac aaaagcttat atgctatata gattgtatta ccccttgttt
    11521 ttaattctat tcataattat tacaaatttt tttaaattac tcttcatgcg ttactttcgt
    11581 tcgtaatcat ttttaaaatg agtaatgtaa tataagggtg ctattatcga ctcagtttgt
    11641 ctaatgcttt ctttggtact tcttcctttt ctacttcttc aaaagtttct acatgatgac
    11701 ctttatgtgt aattttcaag tatctatgcg gtttaacatc aaatgtagca gtatacatta
    11761 attgcgtctc tttcccttct ttattaaaag cactttgagt ataacttcgg agttgatcat
    11821 ccattctagt agacacctct gtcgttttaa cataagaatc atcttccttt actaatgggt
    11881 taaattgatc tgttatacca tgagagtcta ttgtttttaa aatcgttttc aaaagatcac
    11941 ctctgacaaa atataaaata ggatgtctct gaaaacaact tacataattg taattaaaat
    12001 gtaagtatta ggagaaaatg atggtatttg aatctgaaag atacgaatcg tttttaaaca
    12061 aagttatttt atagagacct tattatggaa ttgaaagaag ttaattttaa ggttgtcgaa
    12121 tataaaaaca tattgattaa ccataaaaga gaaattattt ttgtagattt cggcataaac
    12181 gtcattaaag aattttctat atgatggtgc tgatcataac aaagaaagct aggcaccttt
    12241 agatacctaa ctttcaaagt attagcgata aaacactgta tatacttatt taacttaatt
    12301 tcaaacttgt tcaatgtcat taacactttt cacaagatcg aaagttacat tttttatatc
    12361 ggctgtatta atttttacat tttccctatc tttttgtagc tctttatgcg actctaatgt
    12421 atatttacca ccatcttttg tatttatgac gatgttacct ttaggcaaat gttctcccat
    12481 atataagcca taagaaatat gagcaaatct tatgatatga tccaattctt ttaaagtgac
    12541 aacttcttta ttaagagtaa tgttcctctt aggtgtatat actctatcag caactgtgta
    12601 agtcccttct aaatgtatac gaacttgatt ttcatttaaa ggtctctctg aataaaccca
    12661 attcctagat ttattagatt ttccatttat tgtatttttg ctgtatctat cgtacagttt
    12721 tttaaccaaa gctttttctg aattatttgg tacttcttca actttttgga attgtttatc
    12781 ttgtaaactt gaggaatttt gtgttgacgc gcctgctttt gaatatattc caaatgatcc
    12841 cgaatagatg atacctagcg atagaataga ttttaataag attgaatttt tagaatgatg
    12901 ttttttgaac atatttaatt acctccttga tgtaaagctt tatttgctac aattatagaa
    12961 ataatagacg tgttcatgaa ttaacttcat cttaactctt gattaacttt aatttgctac
    13021 cactctgaat ttaataacta taaatcgtct acacataatt ggactaaatc taagagaata
    13081 gaatttgtta atttaaaata gtaagcaatt caaagttata tgtgtaatag ataaaataga
    13141 tatccctata gtgatgcgtt actagctaaa cgtaataaca ctttagaaaa taatgaagat
    13201 aattaagtta aggggttact ggattgtttc gactatgtaa ttaagtataa aaaaacgtcc
    13261 aacgacaaaa cgtaattata aaaaggtaaa atctatagtt cagttttaaa ttgataatgg
    13321 catgcgtatc ggtgaactat ttgcaataaa taaagaaaat ataaactatc aagataaaac
    13381 gctagatatc gacggtaaag ttaattggga aactgattaa aaatggaagc atccggagta
    13441 aaagagacaa ctgaaagaag taatagctat aaggccatag ggctcactac ccaaagcatc
    13501 gacttactaa gaacacttat gcttggaatg ataagtttat tgatagagag tacatattca
    13561 caaatacggc tggtagccct atcgactcga acaaaattag ccacattact aaaggggggc
    13621 tatcaaagag acaactgaga ttagttctat taagaaacct gcaacgacgc atacattaca
    13681 tcattctcat atatctacac ttgctcaatt aggaattaac ttaaaagcaa tgcaagagca
    13741 tgtaggtcat tcagattata aaaactctag agatatacac acatgttact aatcagatgg
    13801 cgaaagatat gatgaataaa tttgaacgat tggggagtta atattggaaa aagatgatac
    13861 actagcagaa attaagccta tgctcaattt tgatgagcaa atagcgaaat taaaacagat
    13921 gaatatattt tttaatatta ttgacaccga aaaagcaaat gaaattctta gaaaaaataa
    13981 ttacttcttc aaactagctt atttccgaaa aaatttcgaa aaaaagaatg gcggctattt
    14041 catagaattt gcttatttat cagatttagc aactatagat atgaaattaa gatacacaat
    14101 gttgcattta actttagata ttgaacatag tttaaagtgt ctagtcttaa aactaataac
    14161 agaaaataac caagaagatg gttataaaat aatagatgag ttcttatgta ttgataaatc
    14221 atataacaat tcaaattttg acacaaattc aagaacacca gaagaagtta tggaaaccaa
    14281 aatcaaaaat aaaaacgaaa tatttaagca tatgaataaa agagggcaac tacccgcaaa
    14341 gttgaataaa tactatcaaa atccacccgc atgggtttgc attgaattca tgcaactagg
    14401 tcaattcgtt tcgtttctca acttctatta caagaagtac aatgacgaag aattgagagt
    14461 tgctaatatt ttaatgcctt tagttaaaaa tataagaaac aaatcagctc ataaccaacc
    14521 catcatagca aatctaaatt atgacagtag atctcctcaa tatttatttg aaaaagggaa
    14581 taatataggc atatctagaa acatgttcgg aataaaaaat ttcatagata ctttcgctac
    14641 tctagaatta cataatcaag tttgtagtaa tgcaattatc caagcaagat atcacgattt
    14701 ggaccaactt caaaagcgat ataaaagaaa cgaaagctat tataataatg cattagctat
    14761 caaaagattt tttatagctt tagataaaat tattgacttc aacagaccaa aagtataaac
    14821 tatctagtga ggaaagagac ttataggtct cgcgagttat tttaattcgt atgcaagaaa
    14881 aagaagagct atgcatttta tttaaaatgc gtagttcttt ttttatgcat ctaaattcat
    14941 attatttttg caatataaac atatctttgt gcaaatcccg aacacaaaac attcacatcg
    15001 tcctttttct gccctttttc tatatcccaa aacacaaaaa cccccgtaag cctatgccta
    15061 cgggggttat aatatattaa atattattgt tcttctttaa catatggtaa taatgccata
    15121 tgacgagaac gtttgatagc tgtagtcaac atacgttgat atttagctga agtaccagtt
    15181 acacgacgtg gtaaaatttt accgcgttct gagataaaac gttttaataa ttcagtgtct
    15241 ttgtagtcga tatgtgtaat accatttgct gtgaaatagc atactttttt acgacgacgt
    15301 ccgcctcttc ttggtccacc tgccatgatt gtgtgcctcc tttgataatt ttttcgcttt
    15361 aatttcgtta atttttatta gaatggtaag tcatcatcac ttatatcaat cggtccgttt
    15421 gcatttgcaa atggattatc agattgtttc gtgtttgatg aattattgta cgaattgttt
    15481 tgccctgatt gttgaccacc gaatccttga ccgtaatctt ggaattcatt ttgttgacgt
    15541 tggccaccat tttgttgcgc atttttaggt tcaaggaatt gaacgctatc acacacaact
    15601 tcagtaacaa acacacgacg accttcttga ttttcataat tacgggattg taagcgacca
    15661 tctacaccag ctaaactacc tttagataaa tagttattta cattatctgc ttgtcttcta
    15721 aaaacaacac agttaataaa atctgcttcg cgctcccctt gagcattcgt gaacgtacga
    15781 tttactgcaa gagtgaatgt cgctacactc acacctgagg gagtggttct gtattccgga
    15841 tctttcgtta aacgacctac taatacaact ctatttagca tttaaacgcc ccctctaatt
    15901 attacttgtc ttcgtcttca cgaataacca tgtaacgaat gatatcgtca ctgattttag
    15961 ctagacgttg gaattcgtca gtagctttat tgttatcaga tttaacacgt acgatgttgt
    16021 agaaaccatc tttgaaatca ttgatttcat aagctaggcg acgtttaccc cagtcttttg
    16081 cttctaaaac ttctgcacct tcagtagcta agataccgtt gaaacgttca actaacgctt
    16141 ttttagcatc ttcctcaatg tttgggcgta cgatgtacat aacttcatat gttctcattt
    16201 tatatttgca cctccttgtg gtctatacgg cttatcaatc ttaaaacaga taagcaagga
    16261 ataattttca ttactcacaa taaagaatta tatcatgcgc cattactttt tacaataata
    16321 attcaaacta ctcttcatat catttttgac attaatacat ttgaaatttt ctatgatatt
    16381 ttttaaaaat acacttcaca aaagcgaaca catgttctat aatggttgtg aggtggtaag
    16441 gaatgaattt aaatattgat tggtctaaag attttcaaga attccaagag atacttaata
    16501 gtggcattca tcctgaatgg ctttattgtg caaaggctaa tcttgtttta gagcctgctt
    16561 atactggcga aggcaaacaa tttttcagca ctcaagatat tattaacgcg agtaaaatta
    16621 ttccattctt ttaataaata acacgcataa ttaaaagagg cgaacaattg attccgcctc
    16681 ttctacatat atactattta attaacttca ctctatcgtt tatacattaa atctgaaatg
    16741 aacgatatcg ccatcttgca taatatattc tttaccttct aatcgttgtc tgcccgcttc
    16801 tttagcgcca ctttcgccac catattgtac atagtcgtca taacttgtta cttcggcacg
    16861 gataaatcca cgttcaaaat cagtatgaat gataccagca cattgaggtg cagtcatacc
    16921 ttgtttaaat gtccaagcac gtacttcttg cacaccagca gtaaaatatg ttgataatcc
    16981 taataattca taagttgttc taattaatcg atctaatcct ggttcttcaa tacctaaatc
    17041 ttctaagaac atttctttat cttcatcatc taaagtagca atttcttctt caatttttgc
    17101 actaataaca atcacttcag agtcttcttg cgctgcatat tcacgaatcg cttttacttt
    17161 atcattatca tcatcaccaa tttcatcttc accaacatta gcgatataaa gcattttttt
    17221 agaagtcagt aattgcgctt ggttcaccca tttttgatct tcttcattaa agtcaatact
    17281 gcgggcaggt ttaccatttt ctaaagcttc tttaatagta tttaaaatgc gcacttccat
    17341 ctcagcagtc ttatcttttt gacgtgccaa tttttcaatt ctaggtaagc gtttttcaac
    17401 tgattctaag tctgcaagta ctaattccat attgataact tcgatgtcat caatagggtc
    17461 tactcgacca gcaacatgag ttacgttatc atcatcaaat gcacgaacga cctgacaaat
    17521 cgcatctact tctctaatat gtgataagaa tttattacct aaaccttcac ctttagaagc
    17581 acctttaaca attccggcaa tatctgtaaa ttcaaatgta gtaggtaatg tttttttagg
    17641 ttgaaccatt tcttctaatt taagtagtct tgcatctggc acttctacaa tacccacgtt
    17701 tgggtctata gttgcgaacg gatagtttgc tgccaaggca cccgcctttg taattgcatt
    17761 aaataatgtt gatttaccaa cgtttggtaa gccaacgaca cctgctgtta aagccatgaa
    17821 tcattctcct atctttgtgt atcatcctga gatacgatga ttttttttag ttttttatca
    17881 aacgtttgac gtggaatcat aatgcttcgt tgacaatttt cacacttaat tctaatgtca
    17941 gcacccattc taataatttt aaaacgattg gttccacacg catgttgttt tttcatttct
    18001 actatatcat ttattccata ttttgacgcc attaaatatg acctccatgt attataaact
    18061 actaaacacc gttttcacta tgattaaaag gtgtcattat tggttgtggt gtcttgatac
    18121 cttcttgtaa aaacattttt tgtacttctt tacgaataat acgcgcacca gagaaacctt
    18181 cacctggtat tgtttctgct gaaaccctta atatcactct agtatcttca aaggcatcaa
    18241 taccaatcac aacaggatca cttacaaata aataatattt actacgcaga gatgtaaata
    18301 atttgtttaa tttcttctca acattatcaa tattttcatc tacagatact ggaattttaa
    18361 caattgctgt tccattcgta attgagtaat tcgttatttc acccatgcta ctatttggca
    18421 agattgtaag ttctccagat attgtattaa tacgtgttga acggagccca attgatttaa
    18481 ctgttccctc tgctacagtt gtaccaccgt tgtttatctt aacataatca cctacatcaa
    18541 actggttttc aaatataata aagaaacctg taattacgtc tttaactata gtttgagcac
    18601 caaaacctac tgctaagcct acgacaccag cacttgcaat tactccttca acactaatgc
    18661 caaatttact taaaatggta gttacaacta taaaccacac aatatattta acaacatttt
    18721 gcaccaatga tattaatgtt ttcgaacgtt ttttattacc ctttttactc ttgttttgta
    18781 ttttaaatcc ttgggcaatc attttatcaa gtattttaat tacgattaat gcaacgataa
    18841 tatatataat tatcatcgct aatttagtag cgacactttc atatgtttca attttagtta
    18901 atggttcgaa tagcgatgaa ataatactca taacttgatc cataattagc gttactccct
    18961 tctatatagt ctcaaataat tttattaata ttgctgtatt cttccaacct actgaagtcg
    19021 catcatcttc aaagaatata gataactatc gatatatcta tagattcaca aagtgatatt
    19081 atataaaatt gtgtaactat ttaccatact tacgatttaa ttgttcaatg attctcacaa
    19141 agtcatcttg tgattcaaac tcaaatgaga ttttgccgac tgattttttt atcgatatat
    19201 ctacttttgc gccatactgt tctcgcaact gtcgttcttg ttgctttata aatttaggct
    19261 tagttatatc tactttgtct gtttccgact ttgacgaaac attttttaat tcattaacat
    19321 ggttttctaa atatctgaca ctccaatttt ctttaacaac ccgtttcgct aacctaagca
    19381 tttgttgttc atctttaatt gccaataacg ttcgtccatg tgcacttgtc agtcgcccat
    19441 cttttaccat gtcagcaatc tttttcggca aatgtaataa cctcaacata ttcgctatat
    19501 acgggcgcga cttactcaat cgcttcgcta cttcttgttg tgtaattttc aaatctgtca
    19561 tcaaacgttg ataactttca gcttcttcaa tcgcatttaa gtcttctcgt tgtaaatttt
    19621 ctatgaccgc cagttccatc atatcttcat ctgttaaatc tttgataatc gctgatacgt
    19681 attttagacc agcaattttc gaagctctaa accttctttc accaactaca atgtaataac
    19741 cttgaactgt ttttctaagc acaattggtt gcaaaatacc atattgctta attgaatctg
    19801 ccaaatcatt taaatgattt tcatcgaaag tttttcgggg ctgatacgga ttcggtttga
    19861 tatccgatat atctatttgc ttaatttgtt catattttgt tttagtaata cgttgatctt
    19921 cactttttga caattcactc acatcacttt ttatttgata acaacagtta aatatatttt
    19981 atgtattcta aatgagtcag acaaccatta accacacttt atttaaaaaa taattcattt
    20041 tttaacttca agataccaaa tacaatttca caaacaaatt aacttttaaa tcaaaatttt
    20101 ctgaataatt gttgacaaat ctttttttac tctgtaagct aattaatatc ttataacagt
    20161 ttaatgaaac gtaaacacaa taaagaggaa agtaaaacac accctgctta tacagagagt
    20221 ctttagtagc tgagagaaga ttttgaaagc gtgtttgaaa atggccttgg agtgttgatg
    20281 ccaatatgag gtgtctacgg gttcgcccgt tatagcgata cagtattaac attgatgtta
    20341 aatggcgtac tggattcttt acgcacgatt ttttgttaat aagtatgaga tagcacatta
    20401 ctatatcctt acttaacgac ttaaattgtg ataattgttc agtaagcata tttactttta
    20461 atgcgtactg aataaggtta tttcagcgat ggaataacaa acaaaggtgg taccgcgaaa
    20521 cataagcttt cgtccttttt atccgattca ttcgggtacg aaggacggaa gctttttatt
    20581 ttttcttata ggagggtctt aatatgaagg atacacagtt agcccaaatc acattaactg
    20641 atgattcaac cggtgctata gcaaatccaa tccatttatc tactgcctac aagcatccaa
    20701 aactaggaca atcgacagga tttgattata cacgtactaa aaatcctaca cgctcaacat
    20761 ttgaaacctg ttttgccaaa cttgagcatg gtattgcatc attcgctaca tcaagtggaa
    20821 tgtcagccat tcaattaata tgtaatctat ttaaacctca tgatgaaatt ttagtttcat
    20881 tcgatttata tgggggcaca tttagattgt ttgagtttta cgaacaacaa tacgatatca
    20941 aatttaagta cgttgatttt acagattatg aacaagttga aaaagaaatc actgataaaa
    21001 cagttgcatt attcattgaa ccaatatcta acccacaaat gattgctatt gatgtaaaga
    21061 cgtactatca actttgtaaa gctaaaggct tattgtcaat tatcgacaat acttttttaa
    21121 caccttatct ttcaacaccg ttagcagaag gtgctgatat agtcttacat tcagctacga
    21181 aatatattgg tggacataac gatgtactag caggtgtcgt aaccgtcaaa gatgaatcac
    21241 tcgcacaaca gttgtttgat tttcacaaca tgactggcgc aacactatca ccaatagata
    21301 gttatttgtt gttacgtgga cttaaaactt tgcatttacg cattgagcgc gcgcaatcaa
    21361 acgcaagaaa acttgctaaa aaatgtcagt cacttcaagc gattgacgaa gtactatata
    21421 gcgggcaaac tggcatgctt agtttaagac ttaacaaggc ctatagcgtc gctaaattat
    21481 tagaaaattt agacatttgt atttttgcag aaagtttagg aggcactgaa acattagtga
    21541 ccttccctta cacacaaaca catgttgata tgccagatgc tgaaaaagat aaacgtggca
    21601 ttgatgagta tttaatccgc ttatcactag gcgttgaaaa ttatgaagac atcgaacacg
    21661 atatcatcca agcattagat aaagctcaga ttggagagat tgtatgacac tttcaaaaga
    21721 gacagaagtg atattcgatt ggcgtagagg tgtggaatat cattcagcta acccaccact
    21781 ctatgattct tcaacattcc atcaaacaag tcttggtggc gatgttaaat atgattatgc
    21841 acgaagtggc aaccctaacc gtgaactttt agaagagaag ttagcacgat tagaacaggg
    21901 aaaattcgct tttgcttttg catcaggtat tgctgctatt tcagcagtac ttttgacttt
    21961 caaatctggt gatcatgtca tcttacctga tgatgtatat ggcggtactt ttcgcctcac
    22021 tgagcaaatt ttgaatcgtt ttaatattga atttacaacc gtagatacta ccaagatcga
    22081 acaaatcgag ggtgccattc aatcaaacac aaaattaatt tatatcgaaa caccatcgaa
    22141 tccctgtttt aaaattactg atatcaaagc tgtttctaaa atagccgaaa agcatgaact
    22201 actggtagct gtggacaata catttatgac accgttaggt caatcacctt tattactagg
    22261 cgctgatatt gtcattcata gtgctacaaa atttttaagt ggacatagcg atttaattgc
    22321 tggtgctgtc attactaata atgaggcaat tagtgaggct ctttatttaa tacaaaatgg
    22381 tacaggcaat atgttatctg ctcaagatag ctggacactt gctaaacatt taaaaacatt
    22441 tccaatcaga tttaaacaat ctgtcgaaaa cgcgcaaaaa atcgtgtcat ttttaataaa
    22501 gcaagatgaa atttcagaag tttattaccc gggacttact gcatctcatt tagaacaagc
    22561 taaaaatggc ggtgccgtta ttggcttacg tttagctgat gagtctaaag cacaacaatt
    22621 tgtcgatgca ctgacattac cactcgtttc agtgagtcta ggtggtgtgg aaacaatact
    22681 ttcgcaccca gcaacaatgt ctcacgcaac actacctgaa gaagtgagac aagaacgtgg
    22741 tatcactttc ggtctattcc gattaagtgt tggtctcgaa gatcctgatg aactcattgc
    22801 agacatcaaa tacgcattaa aggaggcatt caatgagtca attcctcaca caattgaaag
    22861 ataatgtttt agtagctgat ggcgctattg gaaccatttt atactctgaa ggattagaca
    22921 cctgtccaga agcatataat cttagccatc cagataaagt tgaacgtatc catcgttcat
    22981 atatcgaagc tggtgctgat gtcattcaaa ccaatactta tggtgcaaat tttgaaaagt
    23041 taaaacgatt cggtcttgaa gataaagtta aagctataca tcaagccgcc gtacgcatcg
    23101 caaaaaaagc agcaaataaa gatacgtata tattaggcac agttggtggg tttagaggta
    23161 tcaaacaaga ggatatcagc ttacaaacta ttctttatca tactgaaatt caaatagaca
    23221 ccttaattga agaaggcgtt gacgcgctac ttttcgaaac gtattacgac ctagaagagc
    23281 taacaaatgt catttcacga acgagaaaga aatacgacat tccaatcatt gctcaattaa
    23341 ctgcttcaaa cacaaattac ttagttaatg gtcaggcaat caatgaagga ttaaaacaac
    23401 tcgttcaatg tggtgcaaac atcgtgggac tcaattgtca tcatggccca caccatatgc
    23461 aagagtcttt cacacatatt gaattaccag agcacgcata cttatcttgt tatccaaatg
    23521 ccagcttatt agatattgaa aatagtgaat ttaagtatag tgacaatgca caatatttcg
    23581 gccaagttgc tcaaaattta attcgcgaag gtgttcgttt aattggtggt tgctgtggta
    23641 caacgccaga gcacatcaaa tttattaaag aatctattca gacacttaaa cctgttaatg
    23701 acaaaaaagt gattccgata ccaacgaaag cacttttcaa tccatctcaa aataaagtta
    23761 gacaatcatt aacatctaag gttcaagaac gtccaaccgt tattatcgaa ttggatacac
    23821 cgaaacattt ggacacggat agattttttg aaaatatcgc taaacttgat aaagcaaatg
    23881 tagatgcggt aacactcgca gataattcat tggcaactgt cagaattagc aacattgctg
    23941 ctgcaagctt aattaagcaa tattacaata ttgaaccact cgtacatatt acatgtcgag
    24001 accgaaactt aatcggcttg cagtcccatt tacttggatt atcgctcatt ggcgttaacg
    24061 aaatattagc cataactggt gatccttcaa aagttggtca cttaccaggt gcaaccaatg
    24121 tctatgatgt taattctaaa ggattaactg aactcgctct aagatttaat caaggtatta
    24181 acactgacgg tgatgcgctg aagaaacgta cacacttcaa catcgctggc gcctttaacc
    24241 ctaatgttcg taaattagat ggtgccgtaa aacgactaga gaaaaagata gaaagcggaa
    24301 tgtcttattt tataacacaa cccgtgtaca gcaaagagaa aatcattgaa atttaccatg
    24361 ccactaagca cttgaacaaa ccatttttca taggcattat gcctatcgca agttacaaaa
    24421 acgcactctt tttgcataat gaagtgccag gaatcaagat gtcagatgaa attttacaac
    24481 aatttgaagc agttaaagat gataaagcca aaacacgaga actaagtctt aagctttcaa
    24541 aggatttaat cgatactgtt catgaatatt ttaatggttt atacattatc acaccgtttc
    24601 aaaatgtcga agattcatta gaacttgcag catactcaaa atctattact gctcacaagg
    24661 aggcaatatt atgacaacaa ttaaaacatc aaacttagga ttcccaagat taggtagaaa
    24721 aagagaatgg aaaaaagcca tcgaaagtta ttgggcaaag aagatttcta aagaagaatt
    24781 agatcaaaca ttaactgatc tacataaaga aaatttatta ttacaaaagt actatcactt
    24841 agatagcatc ccagttggtg atttctcttt atatgaccat attttagata cgtcattatt
    24901 attcaacatc atccctgaac gtttccaagg tagaactatc gatgatgact tattatttga
    24961 tattgctcgc ggtaataaag accatgttgc aagtgcactt ataaaatggt ttaacactaa
    25021 ctatcattac atcgtacctg aatgggacaa tgttgagcct aaagtgagtc gcaacgtatt
    25081 attagatcgc tttaaatatg cccaatcttt aaacgttaac gctcaccctg tcattgttgg
    25141 tccgattact tttgttaaat tatcaaaagg cggtcaccaa acttttgaag aaaaagttaa
    25201 aacgttatta ccactttata aagaagtgtt tgaatcatta atagatgcag gtgctgaata
    25261 cattcaagtt gatgagccaa tcttagttac agacgacagt gaaagctatg aaaatattac
    25321 acgtgaagct tatgactatt tcgaagaagc tggtattgct aaaaaattag tcattcaaac
    25381 atacttcgaa catgcacatc ttaaattctt aagttcttta cctgttggtg gtttaggttt
    25441 agactttgtc catgataatg gctataacct taaacaaatt gaagctggag attttgataa
    25501 atcaaaaaca ttatacgctg gaattattga tggtcgtaat gtatgggcaa gtgacattga
    25561 agctaaaaaa gtcttaatcg ataaattgtt agcacacact aatgaacttg tcattcaacc
    25621 atcatcttca ttattacatg ttccagtatc tttagatgat gaaacattag atacaagtgt
    25681 tggcgaaggc ttaagctttg caactgaaaa attagacgaa ttagatgcat tgcgtcgcct
    25741 atttaatcaa aacgatagtg ttaaatatga taaattaaaa gcacgttatg agcgtttcca
    25801 aaatcaatca ttcaaaaact tagattatga tttcgaaagc gtgcgtactt cgagacaatc
    25861 accattcgcg caacgtattg aacaacaaca aaaacgtttg aacttaccgg atttaccaac
    25921 aacaactatt ggatcattcc cacaaagccg agaagttcga aaataccgtg cagattggaa
    25981 gaacaaacgc attacagacg aagcatatga aacattctta aaaaatgaaa ttgctcgatg
    26041 gattaaaatt caagaagaca tcggcttaga tgtattagtt cacggtgaat ttgaacgtaa
    26101 tgacatggtt gaattcttcg gagaaaaatt acaaggtttc ttagtaacta aattcggttg
    26161 ggtgcaatca tatggttcac gtgccgtaaa accaccaatc atttatggtg atgtaaaatg
    26221 gacagcgcct ttaactgttg atgaaacagt ttatgcacaa agcttaacag ataaaccagt
    26281 taaaggtatg ttaactggac ctgtaacaat tctaaactgg tcatttgaac gtgttgattt
    26341 accacgtaaa gtcgttcaag atcaaattgc tttagcaatc aacgaagaag tattagcact
    26401 tgaagctgca ggaatcaaag ttatccaagt tgacgaacct gcattacgtg aaggcttacc
    26461 attacgctct gaatatcacg aacaatatct taaagatgct gttttatcat ttaaacttgc
    26521 aacgtcttca gttcgtgatg aaactcaaat ccatacacat atgtgttatt ctcaattcgg
    26581 tcaaatcatt catgctattc atgacttaga tgctgatgtt atttcaattg aaacatctcg
    26641 tagccatggt gatttaatta aagactttga agatattaat tatgatttag gtattggtct
    26701 aggtgtatat gatattcata gtccacgtat tccaacaaaa gaagaaatta ctacagcaat
    26761 caatcgttca ctacaacaaa tcgaccgctc attattctgg gtaaaccctg actgtggttt
    26821 gaaaacgcga aaagaagaag aagttaaaga tgcattgact gtacttgtga atgctgttaa
    26881 agctaaacgc caagaataat cgcagcattt atcatataat aaactaaaaa cgggtgattt
    26941 tatgacacaa tatcctttat ggcaacaatt aaatacttta aaacaagcaa cttgggttga
    27001 tttaacgcat acatttgatc cagaaatacc acgttttagt gagtttgaaa aaggcgaggt
    27061 ttcaacttta ttcactgtta aagatcatgg tttctatgtg caacgttgga atattgtaac
    27121 gcaatatggt actcacattg atgcaccaat tcactttgtc gagaataaac gttatttaga
    27181 agacattgat ttaaaagaat tggtattgcc gttaattgta ttagactttt caacagaagt
    27241 agcgaacaac aatgatttca ttgtaacacg tgcgcatata gaagcatggg aaaaagagca
    27301 tggtactatt gaacctggca cttttgttgc acttcgtacc gattggtcaa aacgttggcc
    27361 taatattgaa acgtttgaaa acaaagatgc gaacggacaa caacatgcac cgggttgggg
    27421 attagatgct ttgaagtact taattgaaga acgccgtgtt gaagctgttg gtcatgaaac
    27481 attcgatacc gatgcatctg tggacgttgt aaaaaatggt gatttagttg gcgaacgtta
    27541 tattcttggt caggataaat accaagtcga gttattaact aatttagatc aattaccaac
    27601 tcgtggcgct atcatttacg ctatcagccc taaaccaaaa gatgcacctg ggttccctgt
    27661 tagagcattt gcaattaaac catcaaatga ctaatattac ccaataaatc cataaacaaa
    27721 taaaaacagg ttataccaac atgtaattaa tactgttgtg ataacctgtt ttcttattat
    27781 ttatactttg atacaactgc agcgatagct tgaccgccac caatacacaa tgacgttaaa
    27841 ccagtttcaa cttcatcatt cagttgatgc aataatgtca ctaatactct agcaccagat
    27901 gcaccaatag ggtgtcctaa tgcaatagcg ccacctttaa cattcacctt ttcaggaggt
    27961 aattttaatt cgcgatctac agctaatgat tgtgctgcaa atgcttcatt taattcaaat
    28021 acatcaatat cgcttaattc ttttttacta cgtttcaaag ccttttcaac agcgccaact
    28081 ggtgcaatac ccataataga aggatctaca ccatgacttc caaagccatc aagcactgcc
    28141 aatggttcga tatttaattc tttagctttg tcttctgaca tgactaacat catcgcagca
    28201 ccatcattga ttcctgatgc attacctgct gtaactgtac cgtctttttt gaaagctggt
    28261 cttaagcgac ttaatttttc gactgataca ttttcacgta caccttcatc cttagtgaca
    28321 acgattggtt cacctttacg ttgaggaatc gatactggaa ctatttcact atcaaattca
    28381 ccattttgct gtgcacgtac tgctttttgt tgtgagttta cagcaaatgt atcttgttct
    28441 tctcttgaaa taccatattg ctctactaaa ttttcagcag taatacccat atgatattga
    28501 ttaaatacat ctgttaaacc atcatatacc atgctatcaa ccattgattg atgtcccatt
    28561 ttaaaaccaa agcgactgtt gttgacaagc attggtgatt gagacatatt ctccataccg
    28621 ccagctagca cgatgtcatt ttcaccagtc acaatagatt gatatgctaa ttgaatcgac
    28681 tttaacccag aaccacatac tttattcact gtaaatgcag gtactgtctc tggtaagcca
    28741 cctttcatag cagcaattcg tgctggattt tgtccttgtc ctgcttgtag tacgttaccg
    28801 atgataactt catcaatctc acttggattc aaacccgtct ctttaataat atgttctatt
    28861 aaagtcgcac ctaaatcata ggctggcacg tctttaaacg cacctccaaa aacgccaata
    28921 ggtgtcctgt atgctgctgc taatacgact ctcgtcatgt catattcatc tccttatgat
    28981 atatacaatt ttattactaa tacgtctaat gaaccaatac gccactaaca tccaatttat
    29041 gaaaccaatt gctacgtatg ttacattttc attcttgtta tgcatttaac aaatcatatt
    29101 atacaatgat gtaatttgtt tgggcaatcg gaaacgtaaa cggtttcact ttaacatttc
    29161 acactcttaa atatgctcta tcatcctcat ctatagtaca aaattatgct ttgatttacc
    29221 acaaattatc attaatcatt tcgcgtaatg actctaatta aatgctatct atcattgcat
    29281 cgctattcac agctggtttc accatcaatt tctcatcaac ttttccttac cattacgtct
    29341 ctagtcaaat attaaatcgc tgatgattgt taattccgca attaccttgc agtcgcccct
    29401 ccttccactt catcgccaaa tcttcctcta ttcactagaa aaaataaata gtatacttag
    29461 taaattaatt acacatctta aaggagttaa aattttatgg ttaatgcatt aacaccaaaa
    29521 catttagctg aaaagcgtgc aggattccat gagttgttct ttgatttaat tttcgtctat
    29581 gccattcaaa aaatcgcaca tgtgatttta acaacacaaa acggttccat ttcagctgat
    29641 ttatttttca aatacatcgt catgagtttg ttcttatggt taatgtggtc tcatcaaaca
    29701 ttttttacaa atcgatttgg tcaagttaca ttcaaagacg tctcgtttat gatgtttaat
    29761 atgtttatca tggtctttct atctaacagc ctatatccgg actttgaaaa gacattcttc
    29821 ccattcttct tatgcgtggc aattatgtat ttaagtatcg gattccagta tttattacat
    29881 atacgtacag ggttagatta tggcgataag cgtacatgtc aagcttttgc ggccgtagcc
    29941 tttgtgattt catttttatc atttctatca ttagtactac cacaaagtat ccattacatc
    30001 cctggatttt taggcgtatt cattgcagcg acaggactta ttccatttca gaaatatctt
    30061 gtattatcac ctgttaatat gatgcattta gtagaacgtt tttcattact aacaattatt
    30121 atctttggcg aggtactggt tggtttagct tcgtcatcat ttagcattga tcattttagt
    30181 tacatttata tattccaatt tatgatttta attagtcttt tcggtgtata ttggatcatt
    30241 actgaaaatt acattaatca taaattgtca tctatcggtt tccgtttatc gtatacgcat
    30301 ttattaatca atatcgcttt aggtgtgatt aatgccgcaa ttgtttttag taataacaat
    30361 aaactaaatg acttgtttga aattaatatg atgtatatca gtgttttaat attctatatt
    30421 ggattatggt taatcacgcc ttatttccat aatgaactga caaacgcaaa atatatttct
    30481 tcttcacttg gcatacttgt agtatcatat atcatcagcc ttatctttaa agggcacgac
    30541 caagtaatga ttatctcggt atccgttgcg actttctgca tcatgctcat ctattttaaa
    30601 aatcaacgtc tacgtcaaag tgatgaatag ataaccttga tctcgatcaa tgtatttgaa
    30661 ctgcatccaa aaatattgtg cttcacagta tatttttgag acaatcatca gttatgatac
    30721 atgatcgagt ttttatattt ccgaggaaat cattggcata taccatcatc aattgataca
    30781 cgcaaataaa tttcagcaac atactcaata atatatacac gttaatcctc actataaaag
    30841 gatgcaattc ccacacaacc taatcttcta aaaacaaatg atatgatata gagatgtcac
    30901 ctcaacctat catctcgcat ttcattccac aacaccaaaa agagcagatg ataatcgtat
    30961 tgatttatca cctgctctaa atattatttc aatgactagc ttcacaccaa gaatattgat
    31021 tatagttctt gtttgttaaa aattttaata gacaatatat aagaaacact tgttataacg
    31081 ataccaatga ccgcatatac tatgacaact agccatcctt cagtgctaat tttttcaaat
    31141 tctaatgccg atgcaccact aaccatacca tatataaaga aaaagaccac gaaagaaata
    31201 agtagtagaa tagatgcaaa tatcataatg acattagagt tttcagcgcc aaatttaaat
    31261 gtcaatggga aaatgataga gtatgcccct atgataccaa aactcattaa acctgacata
    31321 ataccaatca tcacactttg ggtcacaatc gtagtcacaa ctaatccaat cattaaactt
    31381 gcaccgaata agattaaata aaaggcaaag tatgacttaa tataatcact acgtttaacc
    31441 ggtaaagtag atacataata catccatctt gagtcttttt catgtttaat attatcagta
    31501 ataggtgtga ttaacataac cccagccatt gccgaactca ttaacggatt aaatactgca
    31561 aagtatcccg cagctatgat agcgactata aaataaatat atgtttgctt tctcgttgca
    31621 taaaaactac ttaggaacat acctttcatt atacttcacc tcgcattatg attttcgtag
    31681 cgtcatcaat gtgttttaaa ggttctgcat tttcaatttc tgcataatct ttaactaaaa
    31741 tttgatattt cccctttgac aatctagaag ctatgattaa atgcttagga atttcaacat
    31801 ctttatcttc tgtcgtaaca attccatatt gtgctaaaag tatatctttc tgttcagtta
    31861 aaatcattcg tccatctttc ataaacacta atttatccgc taattgttct atatcttcag
    31921 aaatatgcga tgatattaag atgcctccac cttgcgcgac aaaatcttct aatagttcca
    31981 ttacttcttc tcgtccagaa acatccatac ctgcagttgc ttcatctaag attaataact
    32041 tcacatcatg agaaagcgca attgttaaag ctatcttcat tcgcatccct cttgaaaaag
    32101 ttttaatttt agtttgtagt ggcaactcaa aatatttgat taaatcaaag aatttttgac
    32161 tattccaagt cgtataaata gattgaaata ctttatcaat atctttaata gtcaatttat
    32221 taggtactct caaatcatca aacactatac ctatgtgttc tttatattcg acatcatcca
    32281 tagcatgttc ttcatcaaaa aatgtgatac taccgttatc tttatgtcga ttgcctacta
    32341 gaatattaat taatgtcgat ttacctgagc catttttccc aattaatcca actgtctcat
    32401 tagtagaaat cgttaaagat gcatcttgca atttaaaatc cgaatctttg tattgtttgt
    32461 tcacactatc tacgtttaac aatgttgtca tatccatgct cctctttgtt taattttaat
    32521 aaaaacgtct tctcttcaat aaataactaa aggcgttata tatgaaaata gcgatgataa
    32581 gtagcaaact aaagctttga ttaactccag tagtaattga ataaagccca attactacaa
    32641 tggctagtat caatatggat aagttgatcg catatgtttt aaataatgca attaattcta
    32701 tatggcgttc accttcatcc aatatttcca atcgcttttc agtgtaattc ttatctgcaa
    32761 tttttggcat tctatcatca aatcttctat taaacagtgt aaattgtgta ttgaaaatag
    32821 cactagcaaa aaatggtatt aaaaagaata gtattgcatt tgcttcagcg tgtcctacca
    32881 caaaaattag taacactaca aaggcaataa ttgtctgtat aatgcttaat atacttccat
    32941 ttaaaacata acgattcgca agcaattcat attgatctgt tgcatcgata tctacctctt
    33001 catctacaag ccgcttatac ttcaatgcac gtctttgatt catcaaaaca atgatttcta
    33061 ctaatatgat aataatggtc gcaacaattg atattacaac gacattgttg tatgtcgcaa
    33121 acgtcaaatt ctcaataccc aatccatcaa agttacctaa aattccacct atgataccac
    33181 ctacaagtcc acccagtaaa agatatccga tatatcttag tatcttcatg cctcatcctc
    33241 ctcaataata aaaatagttt ccaccttttc attgaagata cgagcaatct ttattgcagt
    33301 taataccgat ggcataaagt tgtttcgctc aattagcgaa atggtttgtc ttgaaacacc
    33361 cgcttgttta gcaagctgcg tttggtttaa gccatctcgt gctcgtaatt ctttcaatcg
    33421 attacgcaca tcgcatcaac tccttaatta cactgtaaat tatatttgtc tttttgacaa
    33481 ctatatttgt caaatctaca caaaaaaata tgagtgtcaa cctatgtatg acattttgaa
    33541 acaaacacct caacgcctac aagtcgtatt tttttacttt cgttacacct tgctgcataa
    33601 ttaatagcat tctaatttta gtatgatgca cgcattttca ctaaatcaaa ccattcaaag
    33661 gagactatta tggcatttac attatctgca attcaacaag cacatcaaca atttactggt
    33721 gttgattttc caaaactatt caaagcattt aaggatatgg gtatgacgta caatattgtt
    33781 aatattcaag atggcacagc aacttacgta catcaatcag aagatgatat tgttacttca
    33841 tctatcaaaa gtaatcatcc tgtcgctcca agatcaaatc aatctatcgt tcaagatgta
    33901 ttaactagac atcaacaagg acaaacagat ttcgaaacat tttgtgatga aatggctgaa
    33961 gctggcattt ataaatggca tatcgatatt caagctggta cttgtactta tatcgactta
    34021 aaagaacaag ctatcatttc agaattaata cctcagtaaa atgtatttat aacaattttt
    34081 taattattat ataaaatatt gttgataata attatcgttc ggtataaagt aaatactata
    34141 tactacttat gatcgaggtt gattatcatg ataactaaca cttttatttt aggcatcaca
    34201 ggcccgacaa gtcttgtcgt cattagcatt atcgctttaa ttatttttgg tccgaaaaaa
    34261 ttaccacaat ttggtcgtgc tatcggttct actttaaaag aatttaaatc tgcaacagaa
    34321 gatttagata aagagtctca cgatacaccc agtaaggaat cgaagcaaca gcgagagcaa
    34381 tagtactgat gatacattaa tggttcactt tagcgaacta cgccatcggt tagtaaaaat
    34441 tttattgtcg ttcgtcatta cggtcatcgt cgtatatgtt tcatcatttt ggtggatgac
    34501 accattcata acgtatatta cccgtgcaca tgtgtcctta catgcatttt cattcacaga
    34561 aatgatccaa atatacgtga tgattatatt tttcatcgcg ttttgtttca tttcaccagt
    34621 catgttttat caattgtggg cattcattgc acctggatta cataataatg aaagtcaatt
    34681 tatttataaa tatagttttt tcagcgtgtt attattctgt gctggcgtcg cttttgcatt
    34741 ttatgttggc tttccaatga tcattcaatt cgcgttaaaa ttatcattaa ctttaaacat
    34801 ttcgcctgtc attggcttta aagcgtattt agttgaactt atccgttggc ttttcagttt
    34861 tggcatttta ttccaattgc caatattatt cataggactt gcaaaattcg gtcttataga
    34921 taccacatca ttgaagcatt atcgaaaata tatttatttc gcttgctttg tgctggcgag
    34981 tatcattgca ccaccagaca taacattaaa tatattactc acattgccac tcatattgct
    35041 ctttgagttc agtatgttca tcgttaaatt cacatgccga ggcaaaccgc caacacatta
    35101 atcttataag aattaatgct gtgattatcg ttatactgca ataccgagta tttccaacat
    35161 cgcaacaaaa aaaacaggca ctcggcctgt tttttatttt ttaaatttaa agattaagat
    35221 agcaactacc ataatataag cagcttgtgc tatcaatggt tcataacttg gatagaagcc
    35281 caaccagtta atcgttggga atccttcaat aacatgtctt ggcatcgcac ctaataattg
    35341 taacttttga atacttacgc caagcatttt gaatcccata ataaaaataa agatcgacaa
    35401 taccctaaat atatagaata taggtatcaa tctgacgata aatctaaata atagcgcaaa
    35461 gacaattaat atcacgatgg ccaagacgat acctatgaca aaatctttgg tcgctaattc
    35521 gcctatcatt cccatataga aaatgataac ctcgacacct tcacgcaaca cagatattaa
    35581 accaatcgtc gctaacaata ccaaattacc attactaatc gcattggcat acatattttt
    35641 aatcatatca ttccagcgtt tcgcatttga acgtttgtgc atccaaacac caacgataaa
    35701 cattaatatg accgcaacaa tacctaatcc cgcttccata ctttcacgaa gaatgccact
    35761 attacctaaa gtttctacaa acgtaattgc taagataata ctcagtacaa gtccggcaat
    35821 tgcaccacca atcacacttg cagtaccctt cttatctttg acattacgcg tcatagtagt
    35881 caatgtcatt acaattaata acacttctag accttcacgt aaaaagataa tcatcacatc
    35941 aacaaagcta taactatggc caacaacctc tttaatttgg ttatttaaat ctactaagcc
    36001 atctttcaca tgtgctttat tatgttcgtc taatacactt tgatagtatg gtattttatc
    36061 ttcaattttc gtatacaaag caccgtcttt agtttgaatt tgaccttcaa catacggcca
    36121 aatttctata aaatgtgtaa gcgcagcatc agcatccgac aattgattgt cgtcgatagc
    36181 tttaatcgcc ttctctaact catcatttaa ttgtgataca tggtattgat catttgcaga
    36241 cgtaccactt ttcttatcga catgatcaat atttgattta aaagttgtcc aagcatgtga
    36301 cacttttgtc gtatctaatg gcgacttatg aattgcaatt ctaagttgta ataatgcgac
    36361 ttcaatttgt ccatattgat ttgcgtcata attgcgaatc accgtttcat tacttgtcca
    36421 aatctgattc aaactattgt tcagcgattc tagctctgct ttatttttat ctttaatcgc
    36481 ttttgtcatc gctgcatctt tggcatcgac ttgctgttgt aatagtttaa ttttagaacc
    36541 cgcatcttta ctagccaatt tctcttcata agcaattaat gacttcgtta attgcgaaag
    36601 tgtatctttt tgatcatcat tcgcttttgc atcttcaagc tttctcacat ctgatttgac
    36661 agcattacct tcactattat cttcaagcga taatttctta actgcactta ccacttgctc
    36721 aattgctttc tgcttattgt cattcgatat cgaattatta gaaagtacag atttcgcatc
    36781 cgtaatcaca ctatatacat cactaatact ttgttgtgct gctgcctgac ttttcagtaa
    36841 cccaaagcta cacaccatag cagcagttat tagcattgct ataattttag tcaaataatg
    36901 tttcaccgag gtatcctccc ttactaacac ctggtaatac taaaaatgaa gcagaacctc
    36961 tatgtgtaat gtattcgttt aatttatcat tactgcctaa attattttga atatcgataa
    37021 attgttgggt cgctttttga aaagcaatga acaacaagcc tgtctcgaag ttacctgtgc
    37081 ggtcatccgt accatcaaca taattaaagg ctctacgtaa aattgacgta ttagcttctt
    37141 tcgctagtct cgtatgagca tctttatcta taatgtactc accgtgacta tctttcgctt
    37201 ttaagtcaat ttcatcaaac tctttcccgc ctgttaacgg cgcaccacta tgtcgtttcc
    37261 gaccaaatgt cgcctcttgt tcttctaatg cagtgcgatc ccacgtttca atgtgtattt
    37321 ggatacgtct gacaacacaa taagttccat gcttcgccca tccatcatca ataaacacat
    37381 aatctttaag ttgattattc ttcctaggat taattgttcc atctttaaat gccattaaat
    37441 tccttggcgt ttccttacct ttagcagaga taaaaccaga ttgcgcccaa cgcaccttaa
    37501 caatatctcg aaacggacga actaaattat gaaccgcatg aaaagacact tgtgaatcat
    37561 ttgagcatgc ttgaatcata atatcgccat cgctgtaatc gtctattaac tgatcattcg
    37621 gaaaatgcgg taaatcttta aaggcatcgg gaattttatt agataaccca attttcttca
    37681 tcaaagactt actaattcca aaggtaatcg ttaacttgct tgcacctaat cctatcgatt
    37741 caccggtatc tactggcggc attaaaggat tgttactggc cttgccaact gcatctccat
    37801 ccatcatacg atcagccata accgtccatt tcttaaacat tgctttaatc gcatcccgat
    37861 cttttgattt caaatctaat gcaacgaatt tacatgtttt ttgcgtcggt gtggtaatgc
    37921 ctggttgcac tttaccataa aattatacgc atctttttcc ggatcttctg gtgtattgaa
    37981 cattgatttg aaagaccaca tgctaccaac accacttgcg ccaattgcaa caccggcacc
    38041 gccaatacct aacattttca aaaatgtacg tcttgaaaat tgcgtactat tgttaacttg
    38101 ttcataattt gtcattcagt aatcacagcc attttactta gtggctctcc taatgcatta
    38161 acagcatctg caaatgcttt acggtctttc ttagatactt tttcaaacga ctcataaccg
    38221 ccgttgttat ctttatattt atccaataac tgattcactt tatcgaagtt catttgaata
    38281 tcatcactta attttttatc ttttttctct aaaataggtt taaataagtc ataaattttt
    38341 tgtgcgcctt caacgttcgc tttaaaatca tataaatctg tatgtgaata aatttcttct
    38401 tcacctgtga ttttagaagt tgcaacttca tttaataggt caacagaacc ttgtaacatt
    38461 aattttggtg tgatatctaa tgtatcagct ttggcatgca attcttttgc atctttcaat
    38521 aattgttgtg catctttttt agtcacatca tcaattttct tatcttcgta taatgctttt
    38581 tcaatcttat gatatcctga ccattctttt tcctttttct cttctttcat atctgcaaga
    38641 cgtgcatcaa ttttaggatc taaatctcca aatgcttctg caactggttc agagcgttca
    38701 taatacatac gaacttttgg atataacgct tttgcttggg ccatatcatt attttcaatc
    38761 gctttaacaa atttttctgt accttttaaa aattcattta actgttcatc agtatattta
    38821 tcatatgctt ttgttgcttg ttttaattct gctttaacac catcatcttt tttcgatgtc
    38881 tttgaatcat ccttcttact atcgtcgttc ccacatgcag caattaataa cgttgatgct
    38941 aataatagcg ttgttaactt tttcattttg acacctcatt atagaaattc tattatcccc
    39001 atagacatgc cctcattcgt actatctcac actccctaaa tgccaagata atacgtggct
    39061 cttaaaatga tgattttaag gcatcctccc atgaacatta tctacttgat aataattatc
    39121 aaaatcatta tattgttata aaataatact gtcaacaacc tttttagttt gaaaataaat
    39181 aaaagagtaa tacttatatg taagtcatta ctcttttgta gtctgattta tcatccttca
    39241 ttatattctg attttaataa actatagatg taactcgatg aataaatacc atttagtaat
    39301 tcattgtcac gtaacatacc ttctctagta aatcctagcc tttcaggaat agctcgactt
    39361 ttttcattat gaactgcggc actgatctca attcgattta agtcaatctc atcgaagcaa
    39421 tactttatca atgcctcaac tgcttgtgtc ataatcccat gaccctcaaa ttgtttatct
    39481 aaataatacc ctattgaagt ttttctgtgc atgtgattaa tttcatgcaa accgataaca
    39541 ccaactagca ttccctcata ccaaatacca cactgaaatc cattaccatc agcaaattgc
    39601 aaaagtcctc ttttaataaa tgcacgcgta tctgatggtt gctcagttgc atctacccaa
    39661 ggtaaccatt ccctaagtga atttcttgaa cgattgatta aattgaaaag cgcttctgtg
    39721 tcatgggctt ctaaaatttt taatcttatt tgttcattca ctttcattcc aaacatacca
    39781 tcacaccctc atttattttt catataattc tgtaaattat cataataata acatattaat
    39841 attacgcctt gtatcttaaa tttgttgtcc ttccccaact tgcattgctt gtagaatttc
    39901 ttttcgaaat tctctatgtt ggggccccgc caacttgcac attattgtaa gctgactttt
    39961 cgtcagcttc tttgttgggg ccccaccaat aagggttgta gtgcctatta ctttgattga
    40021 tgtccttgat acctatcaca caacttaatt taataactac tttattaacc attccaaatt
    40081 tatatttaaa aatactacaa aacagtgcta aaatgctatt aaaggaggca ctgctcatgg
    40141 catcattgaa aaataagcat tttatgattg gactatcact aacatttata gtcgcattat
    40201 ttagcttttt agcagctaaa ttgccaatcc tagataaggt tggcgcatta actatcgcga
    40261 tattaatcgc tattctatat cgtcacttta gaggatatcc tgaacaatat agctcaggta
    40321 ttacgttttc atctaaatat ttattaagat ttgcaattat cctgtacgga cttaaactca
    40381 atatatttga tattatcggt caaggtagta gactattagc catcgatgta ggtgtcgtta
    40441 tttttagtat tgtaatgatg ctctttgtca acaaactgtt gcatggtgac aaaaacatcg
    40501 cattattact aggtgtaggt acaggcgttt gtggtgctgc cgctattgct gcagtagctc
    40561 caatattcaa atcacgtgaa aaggatacag ctattagtat cggtatcatc gcattgattg
    40621 gtacgatatt ttcacttata tatacagcta tctatgctat cttttcaatg acgacaaatg
    40681 tttatggcgc ttggtccggc gttagtcttc atgaaattgc acacgttgtc ttagctggtg
    40741 gctttggtgg tagtgatgca cttaaaattg cacttcttgg taaacttggt agagtattct
    40801 tactgattcc attaaccatt gtacttattt taattatgcg tttccgttca tcagaatcat
    40861 ctagcaaggg tcgaataagc attccttact ttttaattgg atttgtcatt atggccttag
    40921 tgaatacata tgtaactatt ccgtcagcat tgctaaatat tttaaatact gtatcaacaa
    40981 tttgcttatt aatggccatg gttgctttag ggttaaatgt ggcatttaaa gatcttaaaa
    41041 atcgcgcact taaaccgctt atgacaatca ttattacctc aatatgcttg tcatcacttg
    41101 cctttatcgt cgttcactgg ctatatagtt aaataaaaag acgctcaaac acttacaaat
    41161 ttagtgtgcc gagcgtctta tttttatact ttaaaagtcg tattggttgt tttcttcttc
    41221 aagcacatgt tgttgtactt tagcagttcg cattgtggat tgtgccaacg cttttaaacg
    41281 aaatacaaca tcatcattga caatttgttg atttgaaaaa tctttctctt caataaatac
    41341 atacgtttgc atcgtatgtg ctttcatgta actcaatatt ggttttaaat gcatttcagg
    41401 aattaaataa tgtttactag aacctgctgt cgctacaagt cctattacct tgtcacgaaa
    41461 cgcattgacc ggaagcaaat caaatacatt tttcaaagca ccagggatgg aagcttgaaa
    41521 aattggaaaa ccaataaaaa tcacatcagc ctgcattaac gacgtcgtta atttatatac
    41581 atctcctgta gtatctagat aattctttcc aacactaaat tctaattcga ggtctcgtaa
    41641 atccatcaat tctatttggt gtccctcatt gatgacttct agttcatttt ttaaatcatc
    41701 catagcaatt ctcgttttag aacctactgt ggaacctgac aataatacaa tattcatgat
    41761 gacgcccctc ctattttgat aaatgctttt taatcgccgg tataatgtcg ttgccaatta
    41821 actctatatt cttcataaca ttttcaaatg gcacaccgcc aaaatcaagc tgtgccataa
    41881 aacgttgatg accatacaac tcgtgttgat acaatatctt ttcaataatt tgttgcgggc
    41941 ttccaaccat tagcgcttct cgataatctg acgaattagc aaattgctgt ttcggataac
    42001 caacgccacg aataaatgac atccctgtat tcaaatgtgg ataaaattct ctcatagcat
    42061 cctgagttgt ttcagctgta taaaacagac tcgctgtact tactggtaaa gacttaggcg
    42121 aagcatcgaa acctgcttca gttgctgctt gacgataagc atctatagaa cctttaaagt
    42181 tcattgctgg gccaccaaga gttgtaatca tcattggcac accttgtttt cccgctttaa
    42241 tagcacttgc aggtggacca ccaacagcac gccatattgg caatgtatta tcgattggtc
    42301 ttgggaatat tttcatattt ctaagttctg gacgatattt tccagaccaa gtaatacgct
    42361 cagttttatt taactctaaa agtaaaccta atttttcttc aaacaattca tcatagtctt
    42421 ttaaatcata gccaaacaag tcaaaaatac ctgttcttga tgctctgcca gctacaattt
    42481 cggctctacc atgagaaatc aaatctaatg tcgcgaagtc ttcaaatact cttacaggat
    42541 ctgttgcact aataatcgtt gaagaacttg aaactttaat atgctttgtc gcttgggcaa
    42601 ttgcacctaa cacaaccgta tgtgcctgtg ttgtaaaatg ctcctgatga ctttcaccaa
    42661 ctgcaaaaac atcaatacct gcttcatctg ctaatttact tgcttcaata atttcattaa
    42721 tacgttgctc ataactaact ttttcacctt tcaatggatt caataaatga tcacctaagg
    42781 aatacaaacc aaactcaaga ggcgtatttt tattcatttc taattttgcc attaaacatt
    42841 ctcctttata tttcgtgtaa cttactttca atttgttcac gttctgcttc taaaaagtca
    42901 ggcaagttca attgacttcc taattgttca agaggtgtat caatagtaaa tccaggcgct
    42961 tcagtcgcaa attcatacat aattgaatta tggcgatagt ataatgattt aaagaaatag
    43021 cgatcaatta tatctgaatt actttgtggt tgttgttgta atttcttgta aattgcatct
    43081 aagtcactca tttgaggtgt attaactgca atatgatgga tataacctcg tccaggtctt
    43141 tcacgttgtc cctgttgctc aataactaca aaatccgaat ataaaccttg tggtgctaat
    43201 gtcagcacat cgaatgattt attatctctt ttgcgataac ctaagacatt ttccaaaaat
    43261 tctaccgtac gcgctgcatt tctaactctt aattcgactg gccctattcc taaaatttga
    43321 tatgcttgag gtatttcact ataagcgtta tgttgccatt gatgtggtac ttcaaaacta
    43381 tcattaacaa gcagtatgat ttctaagtcg tcttcatctt taaagacaat accttcttgt
    43441 ccaagatagt acaaacgttc agacttaata ccattattat caaggcgttt ttcaaaataa
    43501 tgaagtgccg cttgatttgg tactaataat gaaaatcgat aaatcgtttc agtacctggc
    43561 tgcttatgac ccgcattggg aatttcaaaa aagcttaaaa ttgttccagc tgtacctact
    43621 tcgtccccat aaaacaaatg atacattgac ggattgtctt gattaaccga cttttcaact
    43681 aatcgtaatc caaggacatt tgtgtaaaaa tccttattac gttttgcgtc ttttgtatac
    43741 atggatatgt gatgatgccc tactatattc atactatccc tcctattagt ataaatttta
    43801 taccaaccta cataaaaaag atagttatat gccatttacc ccttttctgc aaataaaaat
    43861 atgtttgcac tccattcgta gatacacagc tagtaagtat aacgacataa taattgcata
    43921 attattaatt tatgttcgac catttacttt tctgactgtt tataaaatgc ttcaaaaact
    43981 aaatctgcaa gatttcacaa aagtatattg acaacgcttt catacatgtc taatataagt
    44041 ttatcgcaca aaatgcatat aaatacatat taaggaggat tttatgaatt ttcttaaacc
    44101 tgcaaagcat attaagcctt tgccagaaaa tcagatagat gatacctata aacgattacg
    44161 tctccaagta tttcttggga ttttcatcgg ttacgctggg tactatttat tacgtaaaaa
    44221 cttttcatta gcgatgccgg cattgcaaga gcaaggtttt acaaaagcgg aactaggttt
    44281 tgcactttct gctgtttcca tcgcatatgg atttagtaag ttctttatgg gtactgtaag
    44341 tgatcggagc aatgctcgga tattcttagt tcttggatta gcactcactg ctatcgtcaa
    44401 tttgttaatg ggatttgtac cgttctttac atcaggtatc ggtattatgt ttgtcctatt
    44461 attcttaaat ggatggtttc aaggtatggg ctggccacct tcaggtcgtg ttctcgttca
    44521 ctggtttagt gtaagtgaac gcggaagtaa gactgccctt tggaacgttg cgcataatgt
    44581 tggtggaggt attatggcac ctattgctgc ttggggtatt acaacaacag catttatcaa
    44641 ctttggttat ttaaaaggtt tcgaaggtgt attcatttac cctgcactct tagcacttat
    44701 cattgccgca atttcatacg tattgattag agacacacct caatctcaag gtttacctcc
    44761 aatcgaaatt tataaaaatg actttgctac aagcgataag aaaacattag aaacagaatt
    44821 aactacaaaa gaaattttat ttaaatatgt actaaacaat aaatgggtat gggcaattgc
    44881 ctttgcaaat atatttgttt atttcgtgcg ttatggtgta cttgattggg cgccagtcta
    44941 cttaagtgaa gaaaaacatt tcgacttaaa agcatcaggt tgggcatact tcttatacga
    45001 atgggctgga attcctggta cattattatg tggttacatt tctgataaat tattcaaagg
    45061 tcgtcgtgga cctgcaggtt tcttctttat gttaggtgtc acagtatttg tattaattta
    45121 ttggttaaat cctccaggca atgcttggtt agacaatgtc tcattaattg ccattggttt
    45181 cttaatatat ggaccagtta tgttaattgg tttacaagca ttagattatg tacctaaaaa
    45241 agcagctggc acagcagctg gattaacagg attatttggt tatctgtttg gtgctgtaat
    45301 ggccaacatc gtcttaggtg ctgtagttga taaattcgga tgggatgtcg gttttatttt
    45361 attaacagca atcagtgtgt ttgcaatgtt gagctttatc ctcacttgga ataaagtagg
    45421 acaagaaacc gttcatcatt aaatgataaa aaataaagtc atatggttat cttatcgaag
    45481 atgatatatt catctcttat aagttcaacc atatgacttt ttattagtat tcaaaaaaat
    45541 atttacattg ccacttttgt gtttgccctg ctgttttatt caattgatta caccacttag
    45601 gataaactct aaaagccatc ttacctttat gttcaaatgt agttaagata cctttttcta
    45661 ccaataattc cctaggaaat aaaaaataac cgcttaattc ttcatcaata actataatca
    45721 ttaagtaatc tgcaaacgcc tctttcgagt atggttgatt acaattgttc tcatcttttg
    45781 tccaacatgc aacaaaataa cctgctttag tcggtgtttt cttagctaac ctactttgat
    45841 atgtttcctc tttaaagcta aatgttaatg cttcgtaatc ttgattatat ttttcttcag
    45901 ttaaatcttt aacgtctaat tcttcactaa aaatatattt caacagtatt ttagatttat
    45961 acatatgcca atctcacttt atttttcata atcgtatcat atatttattt ttttcgaaaa
    46021 atacacttcc gaccgaaata tactcagcca gaggtgtacg aaatatttaa ccttctatta
    46081 attcagatgt atcaactgtc aaacgatcac gtaataaata gacgattaac attgctgcta
    46141 aagcacaaag tgactcagca attaataatg accaaatgac acctgttagt ccaaacaaag
    46201 cattcataat aaataataca ggaatgataa tcgcaccttg taaaatggcc ataattgtag
    46261 caccgcgacc ttgaccagtt gcttgaagca taccagtaaa caagaaacct ataccattta
    46321 ataacaatga tgtcattgtt actttcaaaa taaatgtcgc catctcaaca atggcttgat
    46381 cagtagtaaa tagtccgacc atatgatgtc caattgtaaa tacagcaatc atacatacaa
    46441 caaagataac gccgatagac atgataactg ttttgataac gtctttcata cggcctttat
    46501 ttgccataaa gttatatgca attagtggta caacaccttc acataatccc atgataataa
    46561 gttctggaaa ttgcacaagt ctaaatgaga taccataact tgcaatcgcg aagtttccat
    46621 aatgtgctaa aaataaattt aaaactaatc ctgtgaatcc cattaagata ctcattaaaa
    46681 atgcaggaat accgatttta aagatttcag aaagcatttc tttattaggt ttcgcaagtt
    46741 taatattaac tgacacaacg tcactatttt tcataaaata aacgataaag aatagagcag
    46801 cagcaacatt actgattgca gtacccaaag ctgcaccaac aacgtttaaa tcaaaaccaa
    46861 aaattaaaat tggatctaaa ataatattta agcctacact agctaacata ccaatcatag
    46921 aaatcattgg tgccccaatt gcacgtgcaa attgttctaa tatgaagaac aaaattacaa
    46981 aaggtgcact taaaaacatt actttcaaat aattacttgt taaagctaac gtttcacctc
    47041 tcgcccctaa aattgctgcg atttgatcac tgaatggtaa agtaactaaa atcacgataa
    47101 gtcctagtgc aataccacca taaatagaga aactacttac aaatttactc ttactatagt
    47161 ctttcgcacc taataaacgt gaaatataag ttcctgcacc aacgccaaat aaattaccca
    47221 accccattaa gatagcaaaa actggcagtg ttagagagat agcagaaatc atgtggctat
    47281 cttctaaaaa tcctataaag taaatattta atatgccata aataacgctt aataaagtcc
    47341 ctatcatcat tggcaatgag aaatgcatca tcgctttaaa tactggcgat ttctcaaaat
    47401 aatataattg ttcgtctttc attgttcaat actccttgtc tttttcaata attagcttac
    47461 taacaattag atatctaact ataatattaa agataaagtg actgatttct accagtcacg
    47521 cttaccattt attgtaaact agataacatt ttagttaagt ttgctttcat ttgttcattt
    47581 tcttcttcag ataactgcga tacgagtgtt tgctccattt catcaaatat cgaagtgaat
    47641 gcttctacaa gtttaatccc agaggtagtc agtcctatat tctttcttct cgtatcttgt
    47701 gcatcgacat agcgatagat cagcttttta cgttcaaggt tccttaataa attactgaca
    47761 gttggacctg ttcgttgtaa tgctttagca atatcatttt gtgtcagtcc atcttgttga
    47821 tgtgcataaa gataacctaa cgtatgacct tgctcatttg taatatcaaa ttgctctaac
    47881 ttttgatcag ccttttgttt catctcatga ctaatcattc taaataaata cgaataagtg
    47941 aattccattt attgcaccac catttcgtta gatgtctaac taaatatact gcgacatttt
    48001 taaattgtca acatgaatat ctaatttatt ttaaaaattc ctataaaatc ttgcgccata
    48061 aacattttga tatgcaattt ttcggattaa aatatgaaag agattgcata tctacgtttt
    48121 cgagaaatcg cttacaatta caaataggag gatattacgt tgttaagtta tagacaaatc
    48181 gaaattttgt atcttttaat tcatgagcaa acgtttattc caatcaatac cattgctaat
    48241 caacttggtg tatcacctcg taccattcaa tatgatatag catatattga gcaatatgct
    48301 gaaacttatc attaccaagt cagtcgtaat aaagctgcag gcatcaaagt aacaacagct
    48361 cacgcgacac tattaaatga attagagcac aatctaacga atcaaattca tttttcaaaa
    48421 gatgagcgac tcacacatat cgctttaaag ttattcgaaa caactgaccc tgtttcaaca
    48481 aagcaacttg cgcaagatgt taatgtttcg cgtcggacaa ttgcagatga tattaaaatg
    48541 attcaagccc aactagatca ataccattta aagttaaatt atgtccacaa taaaggattc
    48601 aatattattg gtgaggaaga ttattatcgt aaagcgtatg cacactttat acatcaatat
    48661 atgaaacaag ctgcaccttt tatagaggct gatatcttta attcagaatc aatcgcattg
    48721 gttcgccgtg ccattattaa gacattaaat agtgaaaatt atcatttagt tcagtcggct
    48781 atcgatggct taatctatca tatactcatt gccattcagc gtctaaatga aaatttttcg
    48841 ttcgatatac ctatcaatga aattaataaa tggcgacata ctaatcagta tgctattgct
    48901 tcaaaaatga tagaaaactt agaacgcagt tgtaatgtca catttccaga gtctgaaatt
    48961 atctttatca cgttacattt actaggctct aaaatgaccg aacatacagc atcttcaatt
    49021 acctttgaat atcatgattt atcgcaaaat atacatgaat tgatcacttg tgttagccaa
    49081 gaattaggca ttgatatgtc aaaagacaac aagttgcata ccagtctgat cacacatatc
    49141 aaaccagcta tacatcgtat taaatacgat atgctacaac ctaatccttt gaggcaagaa
    49201 gttatgcgtc gctatcctca aatcatagaa gccgttagca agcatattag cccaattgaa
    49261 caggatgctg ctattcgctt caacgaagat gaattaacat acattacaat tcatttcgca
    49321 tcaagtatag agcgtgttgc aacacataag caatcaatga ttaaggttgt cttactatgt
    49381 ggttctggta taggcacgtc gcaactttta aaatcaaaac taaatcatct gtatcctgag
    49441 tttcacattt gggatgccta ttccatttat caattggaag aaagtcgatt attgcaagat
    49501 aacattgatt atgtcatttc aacagtacct tgtgaaatat cagctgtacc agttattcat
    49561 gtcgatccat ttatcaatca acaatctcgt caaaaattga atcaaattat caatgactca
    49621 agagaacaac gagtcatgaa aatggcaact gatggcaagt cactcgcaga tttattgcct
    49681 gaacatcgca tcattataaa taaacaacca ttatcaattg aatccgcaat tgcagtggct
    49741 gtgcaacctt taatcaatga tggcattgtc tattcaaatt atacagctgc aattttaaaa
    49801 caatttgaac aattcgggtc atatatggtc attagtccac atattgcact tattcacgct
    49861 ggtactgatt atgtacagaa tggtgtaggt ttcgcactaa catatttcac tgaagggatt
    49921 atctttggta gtaaagctaa cgatcccgtt caccttgtaa ttacattagc aacggaccac
    49981 cccaatgcac atttaaaggc attgggacag ttaagcgaat gcttaagcag cgacttatat
    50041 cgacaagatt tcttagatgg gaatattttt aaaattaaac aacacattgc tttaactatg
    50101 acaaaggagg cttaataacg tgtcattaga cattttgtca acaacacgca tcattgtaaa
    50161 agaacaagta aatgattgga ctgaagctat aactatagct tctcagccat tactacaaga
    50221 acaaattatt gaacaaggct atgttcaagc aatgattgat agcgttaatg aacttggacc
    50281 ttatatcgtt atcgcacctg aaattgcaat tgcacatgca agaccgaaca atgacgtaca
    50341 tcaagttggt ttaagtctat taaagttgaa ccaacatgtg gcattctgtg atgaaaatca
    50401 ctacgcatca ctcatttttg tattgagtgc catcgacaat cattcacact tatctgtatt
    50461 acaaaattta gcaaccatac tgggcgataa ccaaacagtc cagcaactat taactgcaac
    50521 aaacgcacaa gacattaaaa acattttaaa ggagcatgat taatatgaag attttagtag
    50581 tatgtggcca cggtttagga agtagtttta tggtagaaat gaacgcacaa gaagcactta
    50641 ggcaacttaa tgcaccatct gatatcgaag ttgaacatag tgacattatg acagcaagtc
    50701 cagagatggc tgacttgttt atttgtggta gagatttagc tgaaaatgcc gaacgtctag
    50761 gggatgtctt agttcttgat aatattttag ataaagctga attacaacaa aagctctcag
    50821 aaaaattaca acaacttaac atgatttaaa ggaggtacga cctatgcaag caatccttaa
    50881 ttttatagtc gatattttaa gtcaaccagc cattcttgtt gcactgattg cctttatagg
    50941 tttaatcgtt cagaaaaaac ctgccgcaac gatcacttca ggaaccatta aaacgatatt
    51001 aggcttctta attttaagtg caggtgctga tgtcgtcgtt cgatctcttg agccattcgg
    51061 caaaatattt caacacgcat tcggtgtgca aggtatcgta cctaacaacg aagctatcgt
    51121 ctcactagcc ttaaaagatt ttggaacaac agctgcactc atcatggtct gtggcatgat
    51181 tgttaatatt ttaattgccc gcttcactaa tttaaaatat atctttttaa caggtcatca
    51241 tacattttac atggctgcgt ttttagcaat cattttaaca gtcagtcata ttaaaggctg
    51301 gctaacgatt gttatcggcg cactcgtatt aggattaatc atggcagtct tacctgcatt
    51361 actccaacct acgatgcgaa aaattacagg gaatgaccaa gtagcgttag gtcattttgg
    51421 ctcaatcagt tactttgccg caggtgctgt aggtcaatta ttcaaaggta agtctaaatc
    51481 aacggaagag attaaatttc caaaaggctt aagtttctta cgagaaagta caattagtat
    51541 ctcgattacg atggcattac tttacttcat cgcatgctta tttgcgggcg ttagttatgt
    51601 acacgaatct attagtgatg gtcaaaactt tattgtcttt tcattaattc aaggtgtgac
    51661 atttgctgct ggtgtattta ttattttaac cggcgttcgt ttaatcttag ctgaaatcgt
    51721 cccagcattt aaaggaattt ctgaaaagct tgtaccaaat tctaaacctg cattagactg
    51781 ccctattgtg ttcccttatg cacaaaatgc agtattaatt ggattctttg tcagctttat
    51841 tacaggtgtc atcggtatgt ttatcttatt cttatttggt ggcgtcgtca ttttacctgg
    51901 cgtagttgca cacttcttct taggtgcaac ggctgctgta ttcggtaatg caagaggcgg
    51961 tattaaaggt gctgttgctg gcgccgctct aaatggtatc ctaatcacgt ttttaccatt
    52021 attattcttg ccatttttag gcgaattagg tggtgctgca acaacattct cagatacaga
    52081 ctttttagct gtcggtatcg tgttcggtaa cgcagtaaaa tatatgggat tatttggtgc
    52141 gattctattt attattatcg taggtgcgac agcaatttta ttaaaaggtc gtcaaaagcc
    52201 acagcaatag tgttaacgta aaaatataaa acaccgtcac atattgagtg aatgcccctt
    52261 ttatcaagag gaaagccact tacttatgga cggtgttttt gtattatatt aaatgaaatt
    52321 taaccatact atcaattgct gctaaaattg cttcttcttg tgtcgcaatc ggttcccaac
    52381 caagtaatgt ttttgcacgt tcgttactta cattgcggtt catatctaat aaaagtttac
    52441 cttctttagc ttgatgatta aatttagcac ctagactcaa aataaagtct ggcaattttt
    52501 tagtagcaac tttttgagct atttcaggtc gtttttcttt aattaatttt gcaatttcca
    52561 ataaattaat ttgtccatca gccgtagcaa taaatcgctt gccattagcc tgttcatttg
    52621 tcattgccaa aatgtgtagt tctgctacat ctctcacatc aacaacattt aatggaattt
    52681 gaggtacacg tttcattgaa ccattcaata aattttctaa taaatgaaag cttcctgaaa
    52741 catgtgcatc taatgatggt ccaaaaattg caactggatt gattgtggca aattctactg
    52801 tcgtattttc attgtcaaca aaatcccacg ctgccttttc agctaacaat tttgattttt
    52861 catatactga taagcctggt tcatcttgat ttgtccaatg actttcattt gtgattgaat
    52921 ttttatcttt attactaaaa ccaactgcac caaagtttgc agtcatcacc acacgcttca
    52981 cgccagcatg ttctgcagct cttaaaatac gttgtatgcc ttcaatggca ggcttcgcca
    53041 tcacttctgc atcgtctgtt ttaccgaaaa acactggaga tgccacactc aacacatatt
    53101 tacaatcttt cattgcttca tcccaatgtt catcttgtga taaatccgct tcgacaaaca
    53161 ttaatcgctc tgtggaaata ccattgtctt gcattgtttt aattacttta tcagctttac
    53221 ttaaatcacg tatcgtcgtt ttgacctcat aaccttgttc taataatcgt gaaatgattc
    53281 gcatgtcaac aaaccctgta ccacccgtca ctaatacttt attattcatc acataatctc
    53341 ctctttgtgt ctattgatta ctcattatag cagtcattat attttgacgt atataaatag
    53401 actttggtag ctagtattta atcttactgg tataaatgaa aatgaattta ttcctttaaa
    53461 aactatcatt gaccattttc aaatacccaa tcactaataa acacaaacgc tataaatatg
    53521 atgtctttgc taattaacta aattcatttt caatcgtatg ttcaaattac ataactacat
    53581 agtcaccatt ttaaaagcaa atacacatat tcaacgaggg tgcgacatta acgcctaaac
    53641 aaaattaact taaaatcatc tcaaccaatg attcaaccgt aacattacca aaataataaa
    53701 cgatgtctaa ttgctttaac tgatgcgtta aatcttctct tgtcattttt gttccttgta
    53761 gcgcttgttc cacatctttt atatcacctt gtccaaagaa atcaccaaaa attctacaat
    53821 ctgcaatacg attttgttca acagaaatgg taatatctac agtacctgat gataatcttt
    53881 cacttcgatt atattcatat ttgggtgact tgccataatt ccaatcccaa tttttatact
    53941 ttttatcagc taattcatca atcgcttccc aatctgcttc ggataattca tacctttttg
    54001 cctctttaat gtcatcgatt cccaaaatct gcgtcaccat taaattttta aattcttcaa
    54061 tggttatacc acgatacttt tcatccaatg cttctctaag atgaccaaca cgtgcgcgca
    54121 cagatttaat ccctttcgat gcaatctttt tgcgattagg ctttaacact ttatccattg
    54181 cttcataatt aacatcaagt aatagcgaat aaccgccata aatacgattg ttcattaatg
    54241 tcattgcggc gcctgacact tttttgccgt tcaatgttaa atcatttcta ccgctttgta
    54301 tcacatctct tgcacctaat gtatgcaatg cctttatagc tggttgataa aatcgttgaa
    54361 aatcaccata aattgaagtg tcttgttcta aaatacaaca catattaacg gcacctttat
    54421 caacatacac agcgccacca ccagtatctc ggcgaactac ttgaatactg tgtttatcta
    54481 tataatcttg attcacttct atagcagtat tttgaaaacg tccaatttcc acttttggat
    54541 cacaataata agggaataaa atatcgtcat ctaaaaagat attctgatta acataaactt
    54601 gcatggcgag tgcaatcgca ccatcagtaa tatattctcc attcctaatc ggttctatta
    54661 agtacatctt ctgtctctcc aatgttgtta tttttcgttg tgctatcgtt ccggagtgct
    54721 gttgtaatca atgttgagat atcatcagtc aaatgtatgg tacgttcttg aattgaattc
    54781 ggaatgcgat atgccttttt attcatcgtc atataaagtg cattttcatt tttacgtgtc
    54841 atacgctgaa aaggatgttt cacaaattgt ggtgtagtaa aaccaattcc aatttccaaa
    54901 tacaacactt tatcatcttg atgttgctct agaaaagcat tataacgttg cagttgcgca
    54961 tgaaattcag catcttcaac catgccaact tccgctttac gtttattcac ttccattgga
    55021 gcatcacatt ttggacatct tggaatcatc tcccaaggta taagcatatc ttgttgcgca
    55081 acaaccattt tacgaattaa atcatcattg cgatacgttt gagcatgaca atgctgacta
    55141 cactgttgca gtatatactc gccttgtata tgaaatacat gcgtcatatc ataatcagct
    55201 acatcgaaag cattatctgc attcgtagtt ataatgtggt actgtttacc ttccaccaag
    55261 gattttaaag cgaggtaaga ctgacctaca ggttgatcta aatagtttaa tgtaataaaa
    55321 cgactctcaa acgcccaata ctcttgccaa ctgccataag gatgtaaact cgcttgcaac
    55381 atatcaaaga agcgatattt ttcaataaaa tccgggaaat tttccgtaaa acgctctcct
    55441 acatatgtaa atccgtcaga tgcagacatg cctgcaccaa ttccaatcac tatcgcatct
    55501 gcttcatcaa tcgcagtacg caatacttca gcctgctttg tcttgtcatc cattaacaga
    55561 gacattgcat tccatttact actctgcatc acggttcaat gcctccttat acagttgtaa
    55621 atccttatct gtaaatacat tgaacacgac tttcaatgtt gaatttgttt ctttgagata
    55681 gctttctact gttcgaacag caatttctgc tgcttcatct tgaggaaaag caaatacacc
    55741 tgtagatata cagcaaaaag cgacatgatt taaactatgt tgatcagcca atttaagaca
    55801 gctaagataa catttagcta acaagtcatg attcatcttt gaaacaggca atcgacgtat
    55861 ttgcggacca accgtatgaa ttatatactt tgctggcaaa ttatatccac gtgttatttt
    55921 ggctttacct acaccttcat tgcgcccttg ttgtcgaatg atctctgcac aatcaagtcg
    55981 aacttgaaca cccgcttttg tatgaataat attatcaatg cagtcatgat tagcttgcat
    56041 acatcctaga aaacgactat ttgcagcatt aacaatagca tcgattttta acgtcgtgat
    56101 atcaccttgc caaacaaaga tattgtcacc ttttatcggc ttcaaatcct tcaaatccgt
    56161 aacatgttga cgattcaaat cacttaacat agcatcttgt acagctaaat attcatcact
    56221 tacaggtaat gccggtctga catttgctaa gcctcgatat aattcccaca aatcttcaaa
    56281 tgaagatggc attaccaata cgtcattgtc atttctctct cgacgcatat cattgattaa
    56341 atattcaagt ctcgctttat ttgattttaa cgtttccatt taagcctccg gtaatgctag
    56401 gaatgcttct ttatcgacat catccaattt gaacaaccaa ttttcttctg gtttttcaga
    56461 gtttaaaatt gtcggttctt cttccgcttt tgtatttcgc tcaataatcg ttcctgacaa
    56521 tggcgtttgc acatcaatga ccgttttcga tgcttcgata ctcacaattt catcatccac
    56581 tttaacttca tctggactta cgaattcaac ataacctact gtcccaatat catcttgcaa
    56641 ttcaggtgtc atactaaaca catacaaatc tcctactttt tctacccata aataattggc
    56701 taactttttc atcttatctt catcctttct cttctattta aaatgctaca aatagatttc
    56761 cgcgagtaat tttaatgttt tacaacgctg ttcaatgcct ggaataagcg gtgctactaa
    56821 cacctcatca acttcaaacg tagcaatgaa atcatctaat tgtgctctaa cctgttcttg
    56881 tgtacctgca atgatgcgtg cttgatgtgc ttgaatcatc tctttgtctc gatcattaag
    56941 cttatacttt tgcgctgtgt ctaccgatgg aaaatgttca aattctgcaa attgtaattt
    57001 acctaataac caaacatcta aggcatgttg taatgctgct acttccgctt cgttatcagc
    57061 tacaatgaca aatacagatg ccatcacctt tgcgtccatt ttaatcgttg atgcttggaa
    57121 atgttttttg taaatatcaa tgttatcctt cgctgcatgt atcgcattta tatccggtag
    57181 caaaaatgtt ccaacagaaa gtcctatacc tagttcagca gctattttgg cagatgttgc
    57241 gctactactt aataaccaca tttctggaaa atgatcaatg tgtggttgga cacctaacgt
    57301 atgcgcactt ggtttatcct ttattgtaag ataatcacgt aataacgaaa tcgattcatc
    57361 gtaactatca tatgtaggat ttattccatc taaagcttgc tttaccatag tagtacctgg
    57421 attattacca atacctaaat caatacgatt tggatataac gctgccatca ttctaaaatg
    57481 ctcagcaatt ttataagggc gatagtgcgg caacatcaca ccaccagaac caactcgtat
    57541 gtgatttgtc tgcgccaatg tatgcatcat caaaagttct ggactactac acgcaaacgc
    57601 tggtacatta tgatgttccg taaaccaaat tcgcttaaag ccaagtcgat ctgctaattt
    57661 tgcaagtgtc actgaatcct gcaacgcctt ttgtgcatcc ttaccttcat ctattaaggc
    57721 atagtctaat acgcttaatt taaccaatcc gtcatctcca aacttatcct gtcatgtcaa
    57781 acagacataa cattttagcg ttcttaatac cattccctct tcatataccc acgtatatga
    57841 taacgttttt caattaactt ttatatcttt tcgcttgtat ttttcttttt catattcata
    57901 ttttcagacc tacaaatgac attcattagt tcaattttaa ttttaaaaat gctttccatg
    57961 taccaattct attctatcaa gactgttcat cattgattat tcattctttc catggtactt
    58021 tgaaaacaat attgaataga aaaggaatca tagtatgtac cgatacaaac cacttttaca
    58081 atcaatccac ttacctaatg gcatcaaaat ttcgaatcgc tttgtattat caccaatgac
    58141 cgtaaacgca tcaacaaaag aaggctatat tacaaaagca gacttggctt atgctgcacg
    58201 tcgctctaat tcagctggta tgcaagtcac cggcgctgct tacattgagc catatggtca
    58261 attgtttgaa tacggcttta atattgatca tgatgcttgt atccctggat taactaacat
    58321 ggcatctacg atgaaacaac atggtagcct cgctattatt cagctagcgc atgctggtcg
    58381 tttttcaaat caagcaattt taaattttgg aaaggtgtat ggaccaagcc ctatgacgtt
    58441 acattcaccg attgaacacg atgttatcgc catgtctcat gagaaaatca atagcatcat
    58501 tcagcagtat cgcgatgcta cattacgcgc gattaaagca ggttttgatg gtgtggaaat
    58561 ttcgattgca caacgtttgc tgattcaaac atttttctca actttttcga ataaacgtac
    58621 agaccattac ggtgccgact cattaaaaaa tcgtgcaaga ttatgtttag aagttatgtg
    58681 tgcggtacaa gaagtgattg ataaagaagc acctgacaat tttattttag gatttcgagc
    58741 aacgccagaa gaaaccagag gtagtgattt aggatatacc attgacgagt tcaatcaatt
    58801 aatcgattgg gtcatggacg tttcaaacat ccaatattta gcaatcgcta gctgggggcg
    58861 acatatttat caaaatacgt ctcgtacacc aggtgaacat ttcggtcgac cagttaacca
    58921 aattgtctat gaacatttag ctggtcgcat ccctttaatt gcaagtggcg ggattaattc
    58981 tccagagtct gctttagatg ctttacaaca tgcagatatg gtcggcatgt cttcgccttt
    59041 tgtcacagaa cctgactttg tgcataaact tgctgaacag cgacctcatg atatcaatct
    59101 tgaattttct atggcagatt tagaagattt agccattcca catgctgctt ttaaagatat
    59161 tgttaaaatg atggattatg gggaaggtct aaagaagcat acccgtgacg ctttacgtca
    59221 attggaacag aattatcatg actcatcgtc ttaagactat ttttcatgga aatttaagac
    59281 agtgttataa tgacatcaat atcaaaaata aggagcctgt atagtcgtga ctgaaattaa
    59341 agataaagta attactaaag atgcgtttga attaccctac acaattatta aagcgaagca
    59401 tcaaccaaca aaaggtgcca ttgtctacat ccacggtggt ggattaatgt tcggtaaagc
    59461 taacgattta tccccacagt atatcgatat ccttacggaa cattacgatt taattcaact
    59521 aagttatcgt ttattaccag aagtaagtct cgattgcatt attgaggatg tctacgcatc
    59581 attcgatgcg attcaatcac aatattctaa ttgccctatt tttacctttg gcagatcatc
    59641 aggtgcatat ttaagtctat taattgcacg agacagagat attgatggtg ttattgattt
    59701 ttatggttat agtcgcatca acactgaacc ttttaaaaca actaatagtt attacgcaaa
    59761 aatagctcaa agcgtaaacg aaacaatgat tgcacaactc acttcaccaa caccggttgt
    59821 tcaagatcag atcgcacaac gttttttaat ctacgtttat gcacgtggca caggtaaatg
    59881 gataaatatg attaacattg ctgattatac tgattcaaaa tataatattg caccagatga
    59941 acttaaaaca cttccacctg ttttcattgc gcattgtaat ggcgattatg atgttcccgt
    60001 tgaggaaagc gaacatatca tgaatcatgt tccacattca acatctgaac gcgtgaataa
    60061 aaacgagcat gattttgatc gtagacctaa tgacgaagca atcactattt atcgtaaagt
    60121 tgttgatttc ttaaacgcta taacaatggt gtaatatatc attattttaa aaaactcaat
    60181 ttatcatcat gataaacagt tattcgatca accatattat tcatacaatt tattaagctc
    60241 ataaaaagat acgcctgtcc ctttagtttt cgctaatgag acaggcgctt tatttcactt
    60301 tactattttg aaattcaaca ctgtgatgtt acttatatct gctgtgccat gttagtagca
    60361 cgaaatacat agcatattaa attcagaaga tgaatttaac ttgctttcaa ttgtgtacct
    60421 ttaccttcag ttgcttcaac acgcaacaag tcatttataa tacctgtata gaagttggcg
    60481 agttctgcac ctttacgctt gaaatctagg aaatctacac cgataaaatc gacatgatcc
    60541 catccttgta tgattggttt aacttgccag atacctcttc gtgtggcagg ttcatcattc
    60601 gtaacattaa taaatggttg attggatgga tgtaatgacg aaatcactgg tacgacacca
    60661 tcatttttac gccattcttc tcttgcatca tgaccaataa ttctactcgt tgtatccatt
    60721 aagaaaaatg tacctaaatc aggattttca taacctaatg gaccagtatg agatgataca
    60781 cctgtataag tcgtgtacgt aatatttgga ttcatacttg tcatgttgtt caattttgca
    60841 gagccatcta acgttaaatc ataggcagca ttgtcgtctg atgtccaaat tttgctttta
    60901 ctaacgcgtt ttatatagtc aatataactc tcatttggta attgtttaaa gccccattgc
    60961 gttaatccta aatcgatatt cgaatacttg ttacccataa atcgatttaa agcgaacatg
    61021 atttttctaa cagcttctgt atttccaaac ttatcagctg cttgtgaacc attatgtggt
    61081 gttgctaatg ttgtgattga tgcaaccata ttgttatgac caccagtgaa taatggcgat
    61141 atttctccac catgcgcttt atgataggca atttcttctt tgttaccatt tcttaaaaac
    61201 tcttccatta aacgaattgt ttgaccaccc atactatgcc ctacaagatg taccttttta
    61261 ccaggttccc aattaggcat gattccttta tatgttttac catagcgctc atgtccgtat
    61321 ttagctgcat gtgctgcacc ataatctacg cgaccacctt tgatgtaata ataaagttct
    61381 acagcacgat catagttgct accaaatgca ctaacacttg cttgatgtac attatagcct
    61441 tgctttctca attcttcgat aactttaaat ttatttccac cccaataatt tggatataaa
    61501 gcaggtgcat tatcgcctac taatcctaaa aatccatgta caaaaacaac tggatatttg
    61561 ttaagtggtt gtacttgatt cgctttaagt ggtcgaatct ttttagcatc tgctgctgca
    61621 tttgtagtcg aacgtgtttt aggcgcttga agtgcatctt tgattagttg tttattatca
    61681 gtatttttat ctgtcggttt ctctgaggaa ttttgaccat cgatatgttt acttaaatcg
    61741 ccaacttgtg gtttctgttc actttggcga acagtatcat cttgcgttgc atctatgatt
    61801 tgatgcgcgg gttgatgtgt atcttgttga tttggatgtt tgtccgtggt tgcatcttgt
    61861 gcttttgttg atttaggtgc agttttatca ttagatgggg gtgttgttga agttggtgct
    61921 gctttatcat gatggggtaa taccttttgt gccggaatgg atggttgtga tttatcaaca
    61981 tcattcgatt gtgacgttgt cgattgtgat ccattacgtt cagcatgatg ggtattttga
    62041 acctgatcat tttggcgttc agttttgtta atcgcgttat tttggtgtga ctgtttagaa
    62101 ccttgtcgtt cagaatcttg ctttacttga ttatcatttt gcgttctgat tgttttacta
    62161 ttttgtgttg attgatgctt cgatgattga agcgtatctt taccttctgt cactgttcca
    62221 cttttaccat tctctttatg catatcgtct aattgctttc ctgactgcat ttgatgtgac
    62281 gttatcgtat tcccttgttc tcccggttga tttagtgttt ctttttgtgc cgctgcatta
    62341 gacgttggtg ttttttccga ggcttgcgct tcatgtgatg acacaataaa cattgtagcc
    62401 gctaacactg acaccacgcc tattgaatac tttctaatac tatactttct ttcttcttgt
    62461 cctcttaaca tataatcacc tcaaaagtat ttttttgacc ccctcttgag aatgaaaaac
    62521 aactgcacct tcaatataac atgacatata ttattttttg attaagacta caaaattaat
    62581 aaaaatttaa taatacgata ttaaatcgat actaatcatt tacaaatatg tagatttcca
    62641 aataatttat aaacactttt agttgtggcg ttgaatcaac acaacaacat ttaagataaa
    62701 tattttatta agtaatatag tttcaatcta tatataatta gttaatttgt attggtatga
    62761 aaataattca aactatacaa ttatagtaag ttttcagatt tttctaaatt aaaataatga
    62821 ttcatctcat caaggggaag atgcatcata cagttttgtg tattcattta aacaaagggg
    62881 ttgctttaat gaatcaatat cattctaatg cacaacaacc aagtgcatgg cgtttttttg
    62941 tctatagttt agtgggcata ctatgtttct ttattccttt tacgattaat ggtaacaaca
    63001 ctattttcgt cgatcatgtt catctagcca ttcgctcaat cataggtcca cttatgccct
    63061 atgttgcact gattatgatt ttaattggta cagcgttacc aatagtgaga cgtactttta
    63121 tgacttcaat cacaaacttg gtcattacat tatttaaagt tgcaggtgca atgattggta
    63181 taatgtatgt atttaaaatc ggtccatcaa tactatttaa agctaactat ggtccgttct
    63241 tgtttgaaaa attaatgatg ccattaagta tcttaattcc agtaggtgca attgcgcttt
    63301 ctttattagt aggctatggc ttattagaat ttgtcggtgt ttatatggag cctattatga
    63361 gacctatttt taaaacacca ggaaaatccg ctgtcgatgc agtagcttcg tttgtcggcc
    63421 gttattcctt aggattattg attactaatc gtgtctataa gcaaggaatg tacaacaaac
    63481 gagaagccac gattattgcg actggctttt caacagtttc agcaactttt atgattatcg
    63541 ttgctaaaac tttaggatta atgccgcatt ggaatttata cttttggata actttagtca
    63601 tcacatttgt cgtgactgca attactgcat ggctaccgcc aatcaccaat gaatcaacag
    63661 aatattataa cggacaagaa ggagaacaag aagttgctat tgaaggaagc agactgaaaa
    63721 ctgcatatgc agaggcgatg aaacaaaatg cattaacacc atccctcgtg aagaacgttt
    63781 gggacaattt gaaagacggt ttagaaatga ctgttggtat tttgccttct atattatcga
    63841 ttggtttttt aggactgatt gtagcgaact atacaccatt cattgattgg cttggctata
    63901 tcttctatcc atttatttat attttcccaa ttgctgatca ggctttactt gcaaaagcgt
    63961 cagcgatttc tattgtagag atgtttctac catctttgtt agtaactaaa gctgcaatga
    64021 gtactaaatt tgtcgtcggt gtagtaagcg tatcagccat tatctttttc tcagcattag
    64081 tgccatgtat actagcaact gaaattaaaa tacctgtctg gaaactcatc atcatttggt
    64141 ttttacgcgt ggcattgtcg ctattaatca ccatccccgt cgctttactt atttttggat
    64201 aattcaaatt gaaaataaaa tcactatcgt aaacaaacaa aacgagatga acccattaca
    64261 ttcattcagc cacctaagat aattaggtac ctttaattaa tgatggtcat ctcgtttttt
    64321 tatcgttatc atttaatctt ccataacttg aacaaaacgt ttcgtaattt cttttggtcg
    64381 tgttatcgca ccaccaacga ctgaacaatg aacgcctaag tccatcacgc gtttatacat
    64441 atccggtgta atgacattac cttccgcaat aacttttgca tcaacacttt gtagtacatc
    64501 ttttagaaat tggaagtcat tttgataaag taattgtcct tgcgtataac tagtatagcc
    64561 atgtaacgtc gtgccaatat aatcaaagcc aagtcgtgcg gcatttttag cttcttcaac
    64621 ggtcgcgata tcagccatga tttcaacgtt cggtgcatgt gttctaatat atgatactaa
    64681 ttcgtctaac gtttctttcg gacgttgctg taacgttgca tccaatgcaa tgacttcaca
    64741 ttggctttct atcagttcat caacttcttt tgacgttgca gtaatgaaaa catctgagtg
    64801 atcatagtca cgtttcacaa tgccaataac tggtaaatct accgtttctt taattgctaa
    64861 aatgtcttcc ttagtatttg cgcgaatacc aacagcacca ccttcatacg cagctaatgc
    64921 cattttcgac ataataaaag atgaatgcaa tggttcatct ggtagtgcct gacaagatac
    64981 tattaatcca tgtggtaaca ttattcctca ctccataagt cgttttttca cgtaaagtca
    65041 tttacaatat atcattaaga taatttttat caatgctttt tactatcttg aaaatatttt
    65101 tcatatataa tagtaatcat taagatgaag gggtgacaca atgaaatttg agaatcgtgt
    65161 tcaacgttat caacatttat ttacaaaaac tgataaacgc atcgtcaatt atataagaca
    65221 aaatggctat agcgatgcct tttcaacgat taactcctta gcccatgcga ttggtacatc
    65281 accagcaacg atgacacgct ttagtcataa gctggattat gagaatttcc aagatttaaa
    65341 atttaatatt caacaagaaa tgacagagac agttattgaa aatagcccaa ttattcaaag
    65401 aattcataaa tatcatcaac aaatcattca acaaactggt gaatttattg ataacgacat
    65461 tatccaaacc tttatcgaca aacttcaatc aagtcgacat atactctttg ctggactagg
    65521 tagctctggt ttatcagcga ctgaatttta ttatcgtatg attcgtatgg ggctaaaagg
    65581 taatgttact accgattcac atttaatgaa aatatcggca tccctactat ctcattcgga
    65641 tatgtttatt gctatgtcaa atagtggtaa tacttcggaa ttaatttctg cagcggaagt
    65701 cgccaaatct catggtgcat atgtcgttgc catcacaaat ttcgaaggta gtaaacttac
    65761 agattgtgca gatttagtac ttttaacaac ggatcaatcg cgtaataccg accatcaatt
    65821 tatcaacaca caaattgcga cactcttttt aatcgatatc gtgagttatc atttattaga
    65881 aaatacgaat ctgagtcaaa cttatcaaca tactaaatct attatcctag acaacaaata
    65941 actagttgta tattcaaatc cacctgcaac tgtagataat catcgtgatt gtcccaacga
    66001 gttgctaggt gcttttttaa tttcaatacc aaatattttt ttacattttt gagatctata
    66061 cgttcaagcg tcttcaattt aatatgcccg tggcacactg ttggttgata tagtttagat
    66121 tggtcctaga tagagtgtga tgtgtggaac taacaacagc tctcatctct cgtaacggtt
    66181 tcaaattcta ttttagaatg actccttctt tcaatcatca ttgcaaacag ccatataatg
    66241 ctgcatcatt tttactctta gtcgtttgta ttggtgcata aacatagtct tttggtaaat
    66301 agtgtgcaac tttcggctcg atatatttaa tgagattgtc tccttgttca gatataccgc
    66361 caccaattaa tataagccct ggatcataca tgacttgtat ttgggcaatc ccttctgcta
    66421 catcttctgc ccactcattc aatatttgtt ttgcaatatc atcaccttct tcagctgctt
    66481 caaacaacac tggcacatgt gtgcttctcg taaatcctcc gtcaatcatg cgctttttca
    66541 atgcactcgt tgcagcacgt tgctcaaacg ttgtattttc agttggacga tacaataaat
    66601 acccaacttc atttgcctta tgaagttcac cattatcaat atgactttga ttatttttgt
    66661 acgcaccccc aatgcctgta ccaagcgtca tacaaaagat ccgttctgct tgatattgat
    66721 gtaatttcaa ttcgcctagt aatgcagcgt ttacatcatt ttttactttg acataaggag
    66781 acagtgattt taataatcgc ttaaaattag tacctttata attcggaatg gttggccctg
    66841 cgtatacaat ttcgcttttt tgttcatcaa caacgcctgc tgatgaaata cctatgacag
    66901 gttggatcaa ctgatattgc ttcatatatc ctgttacaat ctcatatact ttgtcagtaa
    66961 taagctcact tttgttgtcc ggcgttggta tttgttgata gtcaaacata tttaattgct
    67021 tatcaataac cgccgattta atttgagtgc ctccaatatc gattgcgatg taatacacct
    67081 tactcactcc atttctattg attttgaaaa atattttcat taattataca taaatatgac
    67141 ttcaattttc aaaaagatat tgttacattt tatgatagcg tttacaatta taactgtaaa
    67201 ctatattatc aaatgatttt tggagggact tcataatgaa caaagattta aaaggtttat
    67261 atgcagcgtt actcgttcct tttgatgaaa atggtcaagt aaatgaacaa ggacttaaac
    67321 aaattgctca aaatgccatt gaaactgaag aattagacgg tctttatgta aatggtagct
    67381 caggcgaaaa ctttttatta aatacagagc agaagaagca agttttcaaa gttgccaaag
    67441 aggcagttgg ggataaagtg aaattgattg ctcaagtagg ttcgttagat ttaaatgaag
    67501 ccattgaact tgggaaatat gccacagaac tcggttatga tgcactttct gccgtaacac
    67561 cattctacta tccatttact tttgaagaaa ttagagatta ctatttcgat attatcgaag
    67621 caacacagaa caatatgatt atttatgcaa taccagattt aacaggtgtg aatatttcta
    67681 ttgaacaatt cagcgagcta tttaatcacg aaaaaattgt tggtgttaaa tatacagcgc
    67741 cgaacttctt cctactcgaa cgtattagaa aagcattccc agacaaatta atcttatctg
    67801 gctttgatga aatgttagtt caagctacga tttctggcgt agatggtgca attggttcta
    67861 catataacgt taatggtcgc cgtgcaagaa aaatcttcga cttagcaaga caaggtcaaa
    67921 ttcaagaagc ttaccaacta caacatgatt caaacgacat tatcgaaaca gtgttatcaa
    67981 tggggattta tccaacattg aaagaaatat tacgtcatcg tggcattgat gcaggattac
    68041 cgaaaagacc tttcaaacct tttaacgaag cacatcgaca aacattagat caactcattg
    68101 caaaatacga tttatagaca tcaaagaatc aatacattgt aaaggggatg ttgcccatga
    68161 aagaagttgg atttggcaca ctaaactggg ttgccgttat catttatcta ctagctatgt
    68221 tgttcattgg cgtttatttt accaagcgcg cgagtcaaag tacgaatagt ttctttactg
    68281 caagtggtcg cttgccatct tgggtagttg gtttttccat ttatgctact acattaagtg
    68341 caattacgtt tatgtctaca ccagagaaag catttttaac agattggtca tatattgcag
    68401 gtaacatcgc tatcgtagca attattccat tactcattta tttctatgtt ccattcttta
    68461 aaaagttaaa ggtaacatct gcatatgaat atttagaagc tagattcggc cctagcatac
    68521 gtgttattgg ctcattatta tttgtcgttt atcatctagg gcgtgtagca atcgttatct
    68581 acttaccaac attagcgatt acatctgtat cagacatgaa cccttatatc gttgcatcac
    68641 tcgttggttt actatgtatt ttatatacat ttttaggtgg attcgaaggt gtggtttgga
    68701 gtgatttcat tcaaggcgtc attttattag gtggtgcttt agttatcatt attctaggtg
    68761 ttatgaacat taaaggcggt tttggcactg tctttgcaga tgcgattgag cacaaaaaat
    68821 taattagtgc agacaattgg aaactaaata ctgcggcagc tgccattcca attattttcc
    68881 taggaaatat tttcaacaac ttgtatcaat acacagcgag tcaagacgtc gtgcagcgtt
    68941 atcaagcttc tgatagttta aaagaaacaa ataaatcgtt atggacaaat ggtatcctag
    69001 ctttaatttc agcaccctta ttttatggta tgggtacaat gctgtattca ttttatacac
    69061 atgaagctgt tttaccaaaa ggcttcaata catcatctgt agtgccatat ttcattttga
    69121 ctgagatgcc accatttgta gcaggattac ttattgcagc cattttcgcc gctgcacagt
    69181 ctaccatttc atctagttta aattctatat ctgcttgtat ttcaatcgac attaagcaac
    69241 gcttcttcgg aaaaggtagc gagcgacacg aagttaactt tgcacgtttc attatcatca
    69301 ttgcaggtat tttcggtttt ggaatgtcac tatacttaat tgcttctaat tcaaatgact
    69361 tatgggattt attcttgttt gtaactggat tattcggtgt tccattagct ggtgtatttg
    69421 cagttggtat tttcactaaa cgtacgaata cattcggtgt tatttgtgga ttaatattgg
    69481 gtatcatctt tgcttatgtc tataatggtg ttggcaaagg taactcacct ttctatgtat
    69541 ctaccatttc atttacagtt gcttttgtct ttgcttatat acttagcttc attgtccctt
    69601 caaaacataa aaaagatata acgggattaa caatttttga aaaagataaa ccatcaacat
    69661 acatttcaaa aacggctacg aaaaagtaga ttgttatgat aaaatcccat caccaagtta
    69721 tgatgcgctg ttgcgccaac ttggtgatgg ggtttagctt tgccatgaat ttaatttaga
    69781 tacttcgatt aatttacaat actaagccaa taattgatcc tgaaatgatt gaagctagag
    69841 ttgaaccaag taacagcctc attgcaaagg atgcaacttt ttctccttgt ttatcactaa
    69901 tgcctttaat tgaacctacg atgataccaa ccgtaccaaa attagcgaag cttactaagt
    69961 aaactgaaat gataccttgt gttcgagcag atacatcacc caggacattt ttaaaatcaa
    70021 gcattgctac aaactcattt gtaattaatt tggtcgccat taaagagcca gctggaactg
    70081 cttcactcca tggaatcccc attaagaatg cgattggtgc aaacacatag ccaataagct
    70141 gtttaaagtt caaaccaaca ctaccaaaca tgatattaat tgcttccatt aatgaaataa
    70201 atgctaacaa cattacggct actacaacag cgattttaaa cccatccatc gcactatcac
    70261 caatcatttg gaaaaaggca actttcttag gttttcctgt ttttccattc actgatttcg
    70321 tttccgttga tttagttaag ttatcaattt caacatcact atcatcagat ttatagggat
    70381 tgattacact ggcgatgata agcgcactaa aaatatttaa cattacagct gtaactacga
    70441 acttgggctc aatcatctgc atatatgaac ccaacattgc catactaaca gcactcatac
    70501 cagacgtcgc aattgtatat aatttcgctc tagataatct tggaataata tcttttattg
    70561 ttaaatatac ttctggttgt ccaaacattg ctgttgaaat agcaaagtaa ctttctaagc
    70621 gccccattct agttatttta ttaatagcga tacctacata tttgataata aatggtaata
    70681 ccttaatata attaaagatg cctattaata cagaaatgaa cactaatggc agcaacacat
    70741 ttaaaaagaa cgtaaagcca tttttatttt gtatatctcc aaaaacaaag tttatacctg
    70801 ctttactaac atttattaac ccttcaaaaa atgagcctaa tgcagttaag attgttaaac
    70861 caatcgttgt gttcatcata aataacacaa tcaacacttg aataaatatc attattaacg
    70921 tctttttgaa gtctatgttt ttacgatcaa aactgaataa aaacgcaaca aatagtgcaa
    70981 atgctatccc tgtgatagcg aataaaatat tcatgtatca tcacctacaa taatttatta
    71041 acagcgacag caattttagc acccaacgcc gcattgtttt caacaagttt tatatttgct
    71101 gctaaacttt taccattcgt tttttctaca attttcccta acaagaacgg tgtggcgtcc
    71161 ttacctttaa taccttgatt ttccgcttca acaacagctt catttatgat tgcttcaata
    71221 tatgcttttg ataaggcatg ctcatatgga attggattag caacaacaat gccaccttca
    71281 agatttaact gctgttttgt taaatgaatg tcagcaagtc gttctggcgt ttcaaccgaa
    71341 cttgttaact taacaccgct ttcgcgagtg aagaatgctg gcaattcatt cgtttgatat
    71401 ccaataactg gaacgccttt tgtttctaaa tactccatcg tcttaggtaa gtctaaaatt
    71461 gatttggcac ctgcacagat aacagtgaca tttgttttag acagttcttc taagtctgct
    71521 gaaatgtcca tcgtatgttc tgcaccttta tggacgcccc caatacctcc tgtaacaaaa
    71581 aattgaatac cagccattgc agcacatatc atcgtcgtcg ctacagtagt agcaccaaca
    71641 cacttcatcg caacaacttc tgctaaatcc cttctagata ctttagcaac gtctttacta
    71701 gttgccagta tttctaaatc ttcgctttct aaaccaattt taattttgcc atctataatg
    71761 gctatggttg ctggaatggc accattattc ctgataattt gctctactgt tgttgccatt
    71821 tcaacatttt gtgggtacgg cataccatgc gatataattg ttgattctaa cgctacaatc
    71881 ggttgattgt tctcccgtgc ttgctgaact tctcgagaat actcaatata cttttgtaaa
    71941 tttgccattt ttataatcct ccatatcgtg ataaagttgc tgttgatcta ggttttgcct
    72001 aactgtatat tttgtttcta tcgttttctt tgcgttaacc ataccagcaa ttaatatatc
    72061 ttcagtagac atcccattta accagctata cactactgca gcacagaatg aatcgcctgc
    72121 acctgtaaca tctttcacac tatttgatgg cataactgac ttaatgattt cttcctcacc
    72181 acttcgataa atgagttctt tcacgccatt tgtcacaata acatttttaa cacctaaatc
    72241 attccagcgt ttagcagcta tttttaaatc atcagtagat tctattttta aatttaagta
    72301 tgtttctgtt tcatctttat tcgtgataat ccaatcaata gcatgtaatg aatcaggcat
    72361 atttttcatt tttggggaag aaaccgtggt gataactaat ttgatttgat gtttcgtggt
    72421 ataggcacat aagaagttta atgcctcttt gcctaaattc aaatctacaa taatgcactt
    72481 agcctttttc aataagtgtg aacgcttaat taaaaattca ggcgtaatgt agtcaaacac
    72541 ttccatatct gctaagccat atgtcatgtc gccttcttta ctaattaaag ctgtatatga
    72601 acctgtactc gcattttcaa attgttgaac atgatccaaa ttcataaatg gtgtggacaa
    72661 tcgtttaatc atttcccatt cactatcttg tccactagca gataaaaaag cgaccgtttc
    72721 gccaagccta cctaagttct cagcaatatt tcttgctacg ccaccaatag agcgtgttga
    72781 cgttacagga tttgatgttt ctgcaactaa atttttatgc acataaaact tacgatctac
    72841 attcgctgcg ccaatacaaa caataggata atcttcattt aaaacatatg cctttcccat
    72901 aacatattcc ttttgtatta atcctgaaat aatgtttgct acgctgggtc tagataatcc
    72961 aattgcctca gcaagttcac gttgtgaaat aaacggatta tctttaattc tttttaaaat
    73021 ttctttctca gaatcgctca taacatccct cctcatattg acttaaaata cttgaatcag
    73081 tgaatttaca aaaatatcgt agcatgctgt tatttctgtt gtaaacgctt acatttaccg
    73141 ttatatcaat gatatttgtt tataaaatac gcataatttc gtaaaaagta agttcattcc
    73201 atcgtgtaaa aggtacttga gaaaatgata aatgtttata cagtatgata tttgtcgaca
    73261 ataaattatg acatttttat gtcttatatt tttctataaa aaaacgtgac tcattatcga
    73321 ctgttacatc gactgaatca cgttactatg ttttatttgt ttttactatt caatatgatg
    73381 atgctatgcg tctactgcac ctcgattaat catgtcttgc ttagtaacaa ttggatattt
    73441 tttaaataca attgaaccaa gataacctgc aagcgcacct acaatcgcca ttactacacc
    73501 ataaatcaca attgtcgtcg gatgattaaa tccaaacata actaaaaatc ctgcaatcgg
    73561 tgtagctgta cctgtcgcat cgttaattaa acctgacata gcaataatta aaccagcaat
    73621 cgcaccacca aagaaatttg taatatagat tggaattgga ttggctgata caatatctgc
    73681 ttgtgataaa ggttcaatac ttactgcaat cgtagactta cgatcaccta attttaagcg
    73741 atggaatagc gtcccattca taaatgccga actaaatgct gccatggcac caatagccat
    73801 aggtacaccc gttaaaccta ataatgctgt caatgccatt gaactcaatg gcgctgtgcc
    73861 gacaaccgtg ataataccac ctaaaatgat acccatgata attggattcg tattcgtact
    73921 actttggata atatcaccaa ttcgaatcaa tgtactattc actactggcg ttaataatac
    73981 tgcaataaga cgagctaatg gcgctaagat gacaatcgat ccaattaagt cgacaccatc
    74041 cggcacatat ttctctgtat atttcatcac atatccaatc atataacccg caaagaaacc
    74101 tggtaataaa tccataccac cgcacgcggc tgctataact aatgcatata ctggtgacac
    74161 accgatagct aatgctgtta atccagcggc agcgacacca cctagacctc ccgcagcgtc
    74221 tcctagctct tctaaaaatt taataccgaa tacttcgcca ccaacatatt tattaaatgc
    74281 ttctactaaa aatgttgcga ttgctgcatt agctaatgct cccatggcac gcataccatt
    74341 aggtgcttta tatgtaaata atgtaaaaat cactaagacc aaaaataaaa ataatgtacc
    74401 tatcaataaa tccataacca ttgaccccca ttacgataat tttatattca atccccatat
    74461 ttaaatattg aatacttaga ggccatttta ctacaaaaaa tattatattt cacggaatat
    74521 ttctaatttt cgataataat tattattaat tgaatgtgaa agtttattca aataatacat
    74581 aaacataaaa ataccggcac atgatgtacc ggcttaataa aactattcta ctgtttcatt
    74641 ttcaagatta aggacgccat ctttcatatg atatgaacga tcacaatatg ctttaagtcg
    74701 ttcatcatgt gtaacaataa tacatgcttt ctttcttttt ttggcttgat cacgtagaat
    74761 tttaatgact tcaatcgcat tttcagtatc taacgccgcg gtaggttcat ccgctaaaat
    74821 aatcgacgga ttcgtatata acgctttggc tatcgccaca cgttgtttct gaccacctga
    74881 aatttctgaa ggtaacttat taagcaatga agttagacct aattgtgaca taagttgctg
    74941 atagtcttca ttagacataa cattcttatt tttctttttc aataatgtaa attgttgctt
    75001 taccgttaaa aatggtacaa ggtttgtagc ttgtaaaata aaacctattt cagacattct
    75061 aacttttgcc aatgcttttt gcttcattgt cgtaatatct tggttattga ttaaaatgtg
    75121 cccagatgtc ggcgtttgta aagcacctgc catagttaga aatgtacttt taccagagcc
    75181 agaaggtcca accaatgcta taatatcacc tttatttatc tcaaaatttg tatctttaac
    75241 cgcttcaatg ttacgattcc catctttaaa tgactttgtt acattttcaa atttcaacat
    75301 ttgctacacc tcctacccaa tcgcctttaa cggatctatt tttctaattg ttaaaatgga
    75361 gaataaactt cctaatacag agacaatcat taacacaatt gcaaatacga gcaatgttag
    75421 tacatcgaat ttgacaggta ctgcatcagg taaaaatgca cctgtaacgc ctgttaacag
    75481 taagccaaat gccgtaccaa ataatgctaa tatgagcgtc tgcgaaataa ctacgttcgc
    75541 taaatagcca ttcgtaaatc cttgagcctt taatatgcca aataaacttg ttttttgtaa
    75601 tgtcatgaca tataagaaaa tgcctataac tgtagctgaa atgacaaata agaatgaaat
    75661 cataaagttt aatgttaagt tctgtggttt ataacctggt aaattttcaa taaagtcatt
    75721 aatacttacc gcttcaagct cttggtttaa ttttttgtct ttccaatttg tatcacgtac
    75781 aacaactgca ttaattttat ctccagtcaa tctaggattg attttggcaa tggtagcgtc
    75841 attcgtgaaa atgactggtg acgcattata ttttgcactt tctgtaaaac ctacgatatg
    75901 caatttttca tctgattgag atagtgataa tgtgtcgcca attttaaatc ctttattttt
    75961 aagtgtttca tcagctaaca cttcattatc tttagtcgct ttatgccctt ctattaaact
    76021 cggaactaaa aatgatgact tttcaacacc gaacactaaa acattgtctt tttgatggcc
    76081 attagacaca atttcccctg tttgcttcaa agtagcttgc ttcttgtatt tattttcaat
    76141 atctttcttg ttaaaaacag attgttgcac agtttgattg gcatctttat ttagaacaat
    76201 ggcatctgct tgccacttat caatgccttc tttattcata ttgataagac cattcgccaa
    76261 tccagataat aaaaatagca agtaactaat catcgttaac acaccaataa ttagtccaaa
    76321 cttcaatttg ttgcgccgta tttcattcca agctaaaaac atgcatttct ctccctacta
    76381 ctatgattta aacattgttt atattcttag atgcacgtac gtcgtgttgc gctctgtaat
    76441 gttatacata cacttatcct tcattatacc cgaacttttt atattaaaag caaatttatg
    76501 gaaaatgcaa ttaattgtct attatttttg tacggtacat ttaaaattta aggatcaatt
    76561 taaaaacgcc tacatatacc tttaagtaca tgtagacgtc caattcatat attatttaac
    76621 ttcgcctgtt ttaggatcga attgcttaat agcattttta cgtaatttat cttttgcttt
    76681 gtcacttgct ttatagttat tgttgtaaat tgtagcttcc caactaccat acattgggtt
    76741 agggaaaatg atatatttct taccgaaatc gtctttatgt ttttcaatta atgcttcacg
    76801 agattcagct gtagcttctt ttgggtctgt aaagtctaat aaattatctc caaatagcat
    76861 gacaagttta tgatcctttt gaaccatttg tctgcgtgat tctttactct tatcatcttt
    76921 accttttagt aaaatatgac tcttcttagc ttgagggata ccttgttgtt ttaagttctt
    76981 ttgtgttgcc tttaaatctt tttctttatc tctatcagaa atatagtaga tatcgacacc
    77041 ttttttgtca gcatatttca agaattcttt tgcgccatag acaggtttag ctttagcagc
    77101 ttgtacccat tcatgccaac cttctgggaa aggtttatta tgtattgatg catagccttg
    77161 atatggagaa ttatctaaaa ctgtttcatc taaatccaaa gcaatagcta acttatgttt
    77221 acctttattc tttttaatct ctttatctaa ctgagtcttt gcactgttat aaccttgtaa
    77281 atataatgct tttgcttcag ctgaattttg ataccaagcc actgccataa tattttgatt
    77341 accaagattc accttttgcg atgctggtat agaagcttgt tgcgtttgtt gaacttcagc
    77401 agaacttttg gcaaacgctg tagaatttgt cgtttgtggc gctgaaactg taaccgctac
    77461 cgataatgat gctattgcaa tatactttga aattttattc atcttatcac ctcatgatta
    77521 atatttaaaa tacagttaaa attataaatg catttattta atattgctat actatgaaaa
    77581 gatatttaat attatttctt gaaaagctaa caaatatgtg aacatttcat ataagcatga
    77641 tttaatggga gacctatcac atgagagaga tttgtgattt atcacgtaat aaacttaaat
    77701 tcatttgagt gactaggcct tcctatcaga catattcact catccacgta tcattatgtg
    77761 tacagtgtgc tatctcttat ttacctattg gaacaaccat aaactcatcc atagtttacc
    77821 ttttataaat agcagtcctc actcatacaa tttctcataa aaatcacaac gcttcaacgt
    77881 atttccaact tactttcacc tattttaatt cataaaaacg acactttaat tgtcattatc
    77941 caataatagc aagacgttat tattgcaatc ttttttataa aataatagaa tcatagtatt
    78001 gtcatttaaa gataaagtaa gaacgttttt atttttcaga ttttttaaat tattatgaat
    78061 atctagtttt aggaaggaaa ttacattgaa aaaacaagtt attatttcgg gcctcatgtt
    78121 attttcacta ttttttggag ccggaaattt aatattcccg cccatgcttg gccatacagc
    78181 gggtcaaaat atgtggattg gtatgctagg ctttgctctt acaggcatat tactcccctt
    78241 tattactgtt attgttgttg cattttatga tgaaggtgtt gaaagtgtag gcaatcgtat
    78301 acatccatgg ttcgggttta tttttgctgt cgtgatttac atgtctatcg gagcatttta
    78361 cggtattcca cgtgctgcaa atgtcgcgta cgaaattggt acaagacaca ttttacctgt
    78421 gcacaaccaa tggactttaa ttatattcgc agcaatcttt tttgccatcg tttactggat
    78481 tagtttaaat ccatcgaaaa tcgttgataa tttaggtaaa ttattaacac cgttattact
    78541 attaatggtc gctctattaa gtattgctgt cattttcaac cctgaatctg cactaagtgc
    78601 acctaaggat aaatatataa cacatccttt catttcagga agtttggaag gctattttac
    78661 aatggatctt gttgctgcgt tagctttttc cgtagtcatt gtcaatggct ataagtttaa
    78721 aggcctcaca gatcgcatga aaattttaaa atatgtctgc ttttcaggtc ttattgcagc
    78781 catattactt ggaatgattt actttgcact tgcatacgtt ggggcatcaa cagctccagg
    78841 aaactttaaa gatggtacag atatattgac gtacaactca ttacgagtat ttggttcatt
    78901 tggcaacata gtatttggta tgacagtgat acttgcatgt ttaacaacat gtataggact
    78961 cgtcaatgct tgcgccacat ttactaagaa acacgtacct aagttttctt ataaaatatt
    79021 tgcacttatt ttctctatca tagggttctt atttacaaca cttggtttag aaatgatttt
    79081 aaaaattgct gtaccattat tgactttaat atatcccgtg tctattgcac ttgtactgat
    79141 atcatttgct aacatgttta gcacattcag attcagttgg gcctatcgac tcgcaactgt
    79201 tattacattg attatttcaa ttttacaaat actaaatagt ttcaacttat tacacggtgt
    79261 tattttgaaa tggtttatga tgttaccttt agcagatatc gatttagctt ggcttgtacc
    79321 attcatgctc tttgctatta tcggtttcat catcgatgta gttatacgcc gtccgaaaca
    79381 agcgacaact taatagacgc ataatctcct agtaatgatc gtcgcatcat tactaggttt
    79441 ttttgcatga aaatctgtat ttattcattg atactaactg acgattaatt attttaaaat
    79501 aaatgatttg ttaaaaaatc ctagctgtta ttcaaaaata ttagttttta aaattaattt
    79561 tgtgaaatta ttcacaaata aagtgattca tagtatactc tgattaacaa atgaaaagtg
    79621 aggatgtcat tgtgaaggag aaacatatta aatgggataa aatattttat ggggatgact
    79681 gggtaaataa cgtagtcgaa acaataagaa caaaagatat attacaaagc gtttatttaa
    79741 aacgttattt attacgcgcg atgatggcag gatttattat cggaattatt acggtcttcg
    79801 tattatcagt taaagcaaca cacgaaccag atttaccgcc aggcattgtg aatatggcca
    79861 gtgccattac attcagcttt gcgttagtac tcattttatt tacaaactcc gaactactaa
    79921 ccagtaactt catgtacttt actgtaggcc tgtattataa agtaattaaa ccaactagag
    79981 tattgaaaat atttttattg tgctttgcag gaaatatttt aggtgctgct attttattta
    80041 gtttcatgcg tttttcaaat gtaatgacgc cagatatgtt aaatcaatta tcagcagtta
    80101 tagaacataa aacgttgtct actgggtttg taagtatatt aatgaaagcg atattcgcca
    80161 acttctttat taatatttca ttagttatcg ccatgcaaat tgacgatgta cttgcaaaaa
    80221 tgtttgtcat gatgttcggt gttaccatat tcgcctttat gggttatgaa catgtcgttt
    80281 acaacagttg cttatttatg ggtggtttaa tttatcaagt tgatacattg cacttcatac
    80341 cagctatttc gaatatcgct gcggctttta tcggtaacta tattggaggc ggactcatta
    80401 taggtttatt ctatgcttac ttgaatgatc atcatcaatt ttataaaaat aattaactat
    80461 atttgaacaa tgcgttagtc gatgccttta atatttagaa gtgcattgtc taacgtattt
    80521 ttttaagttc gtcaatgctt tttgtccgat gctatgagca ttatcaaata caaaatgctc
    80581 tcttaaaagc agttattgac tgaaaatcta cttctaagag agcactttat ttaatcggtt
    80641 aatttgttaa aaactaacag aaatataatt acttaagaaa tcttgaaatt tcaatatacg
    80701 atgtttatga taagtcgctt atttcatctt taggcttgtt attagtaagt agtttaatac
    80761 cactgattaa ccataaagca aatgtaatta tgttaccact tattacagct ccaataatca
    80821 acaatatacc actcattttt ttgtttttag atgctttaaa cataccgatt gcacctaaaa
    80881 taattgaaat gattccaaat ataaatagga ataagaataa tacagtgaaa attgctgctg
    80941 ctgtttctgc atcaactggg tcaacctcac cattaactgt tgttgacaca tctgtagtca
    81001 ttacacctga tgctgctaaa accataaata gtaaactaaa taccgttgct aaaccttgaa
    81061 caacaattcc tattattgtc attattttga tcgatttttc cattgtctta ctcctttatt
    81121 attattcaca aacttacgtt tgtgttctta tatataaatg tttaaattta tatcgtattt
    81181 attttaaaaa ttattgtcgc taaagctcat ttactttttg aaactggtta aaagttttaa
    81241 agaaagccta cgttaatctt tttccacttc tacattttca tcttcataat ctgctttatg
    81301 gtctttcata tacttaattg ggtctatttc tctattaatc tctgccttac catcttttat
    81361 ttcatatgcg aaataataca ttttttcacg atctttatat aattgaatac caataacaat
    81421 gactttacca tctttataaa catgtgtatt actgtcttct tgtttaatgt ctgttttaat
    81481 agtgttttgc actttcgagg caattttatt catttgattc tgttttttgt acactttatc
    81541 aatatctttt tgatactttt ctcctttatt agaacaacct gctaatacaa ttgctaacat
    81601 taaaaatact accaatattc ttttcatcat ttttctcctt agatggctgt cattttccac
    81661 acactacaat actgataata tgctttatca ttgtgatgtt tgaacaatgt ttaaccaatt
    81721 gttatcaact taaaattcgt ttaaatgttt gacgcaagat tttgattaat tatgatatta
    81781 aagtcttctt aatataaaca tctatttcag tgttaattta caactattca ctgaaaatta
    81841 tgtcatcata ataaattatg caataactat ttgatacctt tacattgcta tgtatctcta
    81901 aaaattacct cccacacatt tatttcataa ccaaatattt aactatttat aattatagta
    81961 aaaaacattt taatagtata tacttttctc atattttttt gatataagtt ttaaaaaata
    82021 agtcgatgta catcaacttt ataaaataca ctacaataac cttttcaatt aatgacaatt
    82081 ttaaatttat atcgtaattt gttaattagt tgaactcatt tatccatgat gtatggatac
    82141 cgataaacta attgactttt taagttgcaa ataatcttat cttttacctt cttctttgag
    82201 tcaaatgtaa aacaaggttg gttttgcaca gccttttata acatgtctgc tactcttgct
    82261 ctttaacata cttctctact gctcgaattt cttccatttc atattccgtt tctggtaaaa
    82321 caccaaactt tttatacata taatagtttt cacggcccaa ttgatcaaac tctgtattta
    82381 cccaatcaat ataatcaaaa gatacattta atttgccatc tcttgcaaag tcaaattcac
    82441 atgatgtcca tggttcaagt ccttcttctt taaatgcatt tcttaacttc ttaaacaatc
    82501 tatataaatc cgtccacaaa tcataaaata ctttttcaga gacattatac tctctaggga
    82561 tatatgtgta ataattcaat tcatcgctac ctggtttagt ataattaaaa atgacctctc
    82621 cacctccatc atctacatag gcaattacat ataccttttc ccactctact ggtatcatgc
    82681 tgctaatctc atgcgcaatc tcgttgtaca tttgacttag tttttcttcg aaagtcatat
    82741 tatctcccct atagttcagc ttcatcttgc tctttaatat attgctcgat ttctttaatt
    82801 tcttccatct cgtattccat ttctggtaaa acaccaaact ttttgtacat atagtaattt
    82861 tcacggccca attgatcaaa ctctgtatta atccaatcta tataatcaaa tgatactttc
    82921 aatttgccgt ctcttgtaaa gtcaaattcg catgatgtcc atggttcgag tccttcttct
    82981 ttaaataaat tccttaaatt cttaaacaag taatacagat tcatccataa atcatcaaat
    83041 atttcttccg aaacattata atctctagat atattcgtgt aataattcaa ttcatcacta
    83101 cctggttttg tataattaaa aacgacctct ccaccttgat catctacata ggcaattgca
    83161 tatacctttt cccactctac tggtatcata ctgctaatct cattcgcaat ttcattgtac
    83221 atttcactta atttttcttc gaaagtcatg ttatcgcccc taatctctac tttaataata
    83281 acgatatatt tataaataca ttcaaataac ttgaaattct atttttacaa ttcagtaaga
    83341 tctaaatata tccatccatt taaattttca tcctaaattg gttcatcatc ttgaaactat
    83401 ataatctcct tagattcttc agagttttta cttacaatac tcgtttccat ttttcgaaaa
    83461 tggaaacagc ctcgtgatgt tcaacgcaaa taaatgaagg gacaaattta acaaaccgtt
    83521 tgagttactc atgttcatct acctttcatt aatcattatt aaaatttaga tccgctttct
    83581 aaac
//
LOCUS       DAPSKH010000005        60522 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPSKH010000005 DAPSKH010000000
VERSION     DAPSKH010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 60522)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60522)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60522
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.005"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            31..813
                     /gene="modA"
                     /locus_tag="RPH49_000401"
     CDS             31..813
                     /gene="modA"
                     /locus_tag="RPH49_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5123593.1"
                     /translation="MKMKRFIAIVMALFLVLAGCSNSNDNQDNKKDATDNGKKQEIQV
                     AAAASLTDVTKKLASEFKKEHKNADIKFNYGGSGALRKQIESGAPVDVFMSANTKDVD
                     ALKDKNKAHNTYKYAKNSLVLIGDKDSNYTSVKDLKGNDKLALGEVKTVPAGKYAKQY
                     LDNNNLFKEVESKIVYAKDVKQVLNYVEKGNAKQGFVYKTDLYKQNKKIDTVKVIKEV
                     ELKKPITYEAGATSDSKLAKEWMEFLKSDKAKEILKEYHFAA"
     gene            827..1498
                     /gene="modB"
                     /locus_tag="RPH49_000402"
     CDS             827..1498
                     /gene="modB"
                     /locus_tag="RPH49_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDY5123594.1"
                     /translation="MPDLTPFWISIRVAVISTIIVTVLGIFISKWLYRRKGSWVKVLE
                     SLLILPIVLPPTVLGFILLIIFSPRGPIGQFFANVLHLPVVFTLTGAVIASVIVSFPL
                     MYQHTVQGFRGIDTKMINTARTMGASETKIFLKLILPLAKRSILAGIMMSFARALGEF
                     GATLMVAGYIPNKTNTLPLEIYFLVEQGRENEAWLWVLVLVAFSIVVISTINLLNKDK
                     YKEVD"
     gene            1499..2104
                     /locus_tag="RPH49_000403"
     CDS             1499..2104
                     /locus_tag="RPH49_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDY5123595.1"
                     /translation="MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMI
                     AGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAE
                     PSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDT
                     TKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG"
     gene            2273..3277
                     /locus_tag="RPH49_000404"
     CDS             2273..3277
                     /locus_tag="RPH49_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HDY5123596.1"
                     /translation="MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGL
                     VRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDY
                     IAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAF
                     IPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITY
                     GDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITH
                     DILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
                     "
     gene            3308..3814
                     /locus_tag="RPH49_000405"
     CDS             3308..3814
                     /locus_tag="RPH49_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaB"
                     /protein_id="HDY5123597.1"
                     /translation="MGEHQNVKLNRTVKAAVLTVSDTRDIDTDKGGQCVRQLLQADDV
                     EVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEI
                     EGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELN
                     HLIHELTK"
     gene            complement(3816..4310)
                     /gene="moaC"
                     /locus_tag="RPH49_000406"
     CDS             complement(3816..4310)
                     /gene="moaC"
                     /locus_tag="RPH49_000406"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDY5123598.1"
                     /translation="MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQI
                     SNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNI
                     QTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQR
                     QSNQ"
     gene            4373..5632
                     /locus_tag="RPH49_000407"
     CDS             4373..5632
                     /locus_tag="RPH49_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDY5123599.1"
                     /translation="MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDI
                     VATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVR
                     IMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQV
                     INPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALA
                     EKLGLEVGIYKTQQDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAE
                     VLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQ
                     IIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPG
                     GSRGFKAGHTVDIILTESDAAEEELLL"
     gene            5629..6114
                     /gene="mobB"
                     /locus_tag="RPH49_000408"
     CDS             5629..6114
                     /gene="mobB"
                     /locus_tag="RPH49_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDY5123600.1"
                     /translation="MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKKDI
                     QLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEG
                     FKNADFEKVIVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQL
                     T"
     gene            6128..6574
                     /locus_tag="RPH49_000409"
     CDS             6128..6574
                     /locus_tag="RPH49_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein MoaE"
                     /protein_id="HDY5123601.1"
                     /translation="MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKT
                     EYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAISSPHRK
                     DAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE"
     gene            6580..6813
                     /gene="moaD"
                     /locus_tag="RPH49_000410"
     CDS             6580..6813
                     /gene="moaD"
                     /locus_tag="RPH49_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin converting factor subunit 1"
                     /protein_id="HDY5123602.1"
                     /translation="MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINN
                     KKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG"
     gene            6820..7419
                     /gene="mobA"
                     /locus_tag="RPH49_000411"
     CDS             6820..7419
                     /gene="mobA"
                     /locus_tag="RPH49_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDY5123603.1"
                     /translation="MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNE
                     IIISTNAQLATQFQYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMIT
                     GKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFK
                     NVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL"
     gene            7439..8461
                     /gene="moaA"
                     /locus_tag="RPH49_000412"
     CDS             7439..8461
                     /gene="moaA"
                     /locus_tag="RPH49_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDY5123604.1"
                     /translation="MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFL
                     PKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLT
                     TNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGL
                     NVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLT
                     MIEQHFEIDRVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFY
                     GCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVDNRQRKKIN
                     MNYIGG"
     gene            complement(8746..8916)
                     /locus_tag="RPH49_000413"
     CDS             complement(8746..8916)
                     /locus_tag="RPH49_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123605.1"
                     /translation="MFRFISFGQLVVYSTTFIPKKDILQLNDMGCDINVKEPLKIYYV
                     VILKSGIEMIFS"
     gene            9042..9392
                     /gene="sarV"
                     /locus_tag="RPH49_000414"
     CDS             9042..9392
                     /gene="sarV"
                     /locus_tag="RPH49_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarV"
                     /protein_id="HDY5123606.1"
                     /translation="MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEK
                     ISGKELRDTLHFEMLWDTSKIDLIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLL
                     DKITKEIEVLSVTN"
     gene            complement(9494..10705)
                     /locus_tag="RPH49_000415"
     CDS             complement(9494..10705)
                     /locus_tag="RPH49_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5123607.1"
                     /translation="MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQ
                     AFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDG
                     SLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLG
                     MLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIA
                     KEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRL
                     MDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKV
                     SPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLI
                     HGRHVTRNAMN"
     gene            complement(10698..11138)
                     /locus_tag="RPH49_000416"
     CDS             complement(10698..11138)
                     /locus_tag="RPH49_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein"
                     /protein_id="HDY5123608.1"
                     /translation="MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKH
                     QPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEI
                     VCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND"
     gene            11301..12065
                     /locus_tag="RPH49_000417"
     CDS             11301..12065
                     /locus_tag="RPH49_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5123609.1"
                     /translation="MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGY
                     INENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKN
                     KLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKK
                     LQKYIQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIE
                     DGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV"
     gene            complement(12057..12308)
                     /locus_tag="RPH49_000418"
     CDS             complement(12057..12308)
                     /locus_tag="RPH49_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123610.1"
                     /translation="MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILS
                     IFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY"
     gene            12697..13962
                     /gene="femX"
                     /locus_tag="RPH49_000419"
                     /gene_synonym="fmhB"
     CDS             12697..13962
                     /gene="femX"
                     /locus_tag="RPH49_000419"
                     /gene_synonym="fmhB"
                     /EC_number="2.3.2.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II:glycine glycyltransferase"
                     /protein_id="HDY5123611.1"
                     /translation="MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIA
                     VGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKA
                     YAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELL
                     NSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYD
                     ALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMIND
                     AQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNH
                     HMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVL
                     NQPLYQLIEQVKPRLTKAKIKISRKLKRK"
     gene            14079..17246
                     /locus_tag="RPH49_000420"
     CDS             14079..17246
                     /locus_tag="RPH49_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
                     /protein_id="HDY5123612.1"
                     /translation="MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQN
                     PVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTD
                     MDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQ
                     LIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGL
                     FQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASP
                     QQNSKASSSNNISGVPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQ
                     VAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLR
                     NIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYR
                     RLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAI
                     AFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWI
                     VIILSTLILVVTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKY
                     LKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKH
                     PGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTY
                     DQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWS
                     EDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAEVTNKDVGGTT
                     RQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLA
                     PFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQ
                     GMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISS
                     TLLTLVVVPVIYEILFTLKKRFTKR"
     gene            complement(17433..17750)
                     /gene="mspA"
                     /locus_tag="RPH49_000421"
     CDS             complement(17433..17750)
                     /gene="mspA"
                     /locus_tag="RPH49_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane stabilizing protein MspA"
                     /protein_id="HDY5123613.1"
                     /translation="MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLA
                     LTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTI
                     VLF"
     gene            complement(17995..18159)
                     /locus_tag="RPH49_000422"
     CDS             complement(17995..18159)
                     /locus_tag="RPH49_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123614.1"
                     /translation="MSLENQLAELKYDYVRLQGDLEKRESLDLDTSALVRQLKDIENE
                     IRNVRAQMQD"
     gene            18292..19200
                     /locus_tag="RPH49_000423"
     CDS             18292..19200
                     /locus_tag="RPH49_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002487080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDY5123615.1"
                     /translation="MTEQFTMIILLIALGYFLKRINFIKATDSQVIATLVLNVTLPSL
                     VIVNLNSAELKLSFSILPILMIIYGIVAKMIAVWFFRKYDNHMRGSVGMMTGAMNIGL
                     FAYPLIEVIWPKTGLIYFGMADIGGAFVMFGITYFVGSYFSEGSDQFDFKYLGKKLLQ
                     SVPLVTYIVMFILNISHIHLPHVAIDFFSILSHANMPLSMILLGVMLNFTLERKYIPA
                     TIKYLCLHYGLALVGGLLVHVLLPVSDDMIKTTLLVTWMFPVGVAIISYGIQFKYRTL
                     SFIGMTTNLTIIISIIILYVYQAVFV"
     gene            19607..19738
                     /locus_tag="RPH49_000424"
     CDS             19607..19738
                     /locus_tag="RPH49_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123616.1"
                     /translation="MYGAYLINEYHQDFKSIANFKVLKRMINVMMCYCVLFLEPRIS"
     gene            complement(19855..20718)
                     /locus_tag="RPH49_000425"
     CDS             complement(19855..20718)
                     /locus_tag="RPH49_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein GlcU"
                     /protein_id="HDY5123617.1"
                     /translation="MQFLDFLIALLPALFWGSVVLINVFVGGGPYNQIRGTTLGALIV
                     GLGLLITGFAKFNNPTVIIVGLISGALWAFGQANQLKSISLIGVSNTMPVSTGMQLVG
                     TTLFSVIFLGEWSSMTQIIFGLIAMILLVTGVALTSLKAKNERQSDNPEFKKAMGILI
                     VSTVGYVGFVVLGDIFGVGGTDALFFQSVGMAIGGFILSMNHKTSLKSTALNLLPGVI
                     WGIGNLFMFYSQPKVGVATSFSLSQLLVIVSTLGGIFILGERKDRRQMTGIWAGIIII
                     VIAAIILGNLK"
     gene            complement(20899..21786)
                     /locus_tag="RPH49_000426"
     CDS             complement(20899..21786)
                     /locus_tag="RPH49_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123618.1"
                     /translation="MSIVQLYDITQIKSFIEHSNYESASYLYKLPQQYNEIDVLITDA
                     IESPGVFSIKENDSIKAIILSFAYDKNKFKVIGPFVADNYVLSVDTFEKLFKAMTSNQ
                     PDDAVFNFSFEEGIQQYKPLMKVIQASYNFTDYYIEARTRLEEDMHQPNIIPYHKGFY
                     RAFSKLHTTTFKYQAQSPQDIIDSLDDHHHLFLFVSEGLLKGYLYLEIDSQQSIAEIK
                     YFSSHVDYRLKGIAFELLAYALQYAFDNFDIRKVYFKIRNKNNKLIERFNGLGFHINY
                     EYIKFKFESRNVKDQTIPE"
     gene            21852..21947
                     /locus_tag="RPH49_000427"
     CDS             21852..21947
                     /locus_tag="RPH49_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123619.1"
                     /translation="MILTCYNTFNTSFAIIEFKSKISGIDEARSK"
     gene            21973..24108
                     /locus_tag="RPH49_000428"
     CDS             21973..24108
                     /locus_tag="RPH49_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDY5123620.1"
                     /translation="MKSLILAEKPSVARDIADALQINQKRNGYFENNQYIVTWALGHL
                     VTNATPEQYDKNLKEWRLEDLPIIPKYMKTVVIGKTSKQFKTVKALILDNKVKDIIIA
                     TDAGREGELVARLILDKVGNKKPIRRLWISSVTKKAIQQGFKNLKDGRQYNDLYYAAL
                     ARSEADWIVGINATRALTTKYDAQLSLGRVQTPTIQLVNTRQQEINQFKPQQYYTLSL
                     TVKGFDFQLESNQRYTNKETLEQMVNNLKNVDGKIKSVATKHKKSYPQSLYNLTDLQQ
                     DMYRRYKIGPKETLNTLQSLYERHKVVTYPRTDSNYLTTDMVDTMKERIQATMATTYK
                     DQARPLMSKTFSSKMSIFNNQKVSDHHAIIPTEVRPVMSDLSNRELKLYDMIVERFLE
                     ALMPPHEYDAITVTLEVAGHTFVLKENVTTVLGFKSIRQGESITEMQQPFSEGDEVKI
                     SKTNIREHETTPPEYFNEGSLLKAMENPQNFIQLKDKKYAQTLKQTGGIGTVATRADI
                     IDKLFNMNAIESRDGKIKVTSKGKQILELAPEELTSPLLTAQWEEKLLLIERGKYQAK
                     TFINEMKDFTKDVVNGIKNSDRKYKHDNLTTTECPTCGKFMIKVKTKNGQMLVCQDPS
                     CKTKKNVQRKTNARCPNCKKKLTLFGKGKEAVYRCVCGHSETQAHMDQRMKSKSSGKV
                     SRKEMKKYMNKNEGLDNNPFKDALKNLNL"
     gene            24221..25555
                     /locus_tag="RPH49_000429"
     CDS             24221..25555
                     /locus_tag="RPH49_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDY5123621.1"
                     /translation="MKNYFQFDKYGTNFKREILGGITTFLSMAYILAVNPQVLSLAGV
                     KGVSEDMKMDQGAIFVATALAAFVGSLFMGLIAKYPIALAPGMGLNAFFAFTVVLTMG
                     IPWQVGLTGVLFSGIFFAILTVTGFREVIINAIPYQMKMAVSAGIGLFITFVGLQSSG
                     IIVKNESTLVTLGHLTDPPVLLAIFGIVITVILYAIKLPGSIFIGMIITAIVGMFTGL
                     IQMPSGIVGKIPSIEPTFGAAFEAFKDPSQLLTIQFLIVILTFLFIDFFDTAGTLVAV
                     ATQAGIMKDNKLPRAGRALFSDSLATIVGSVFGTTTTTSYIESTSGVAVGARTGFASI
                     VTGCCFLLALFFSPLIAVVTSAVTTPALVVVGVLMAANFAEINWKSFEVAVPAFITII
                     MMPLSYSIATGIACGFIFYPITMLISKKHKEVHPIMYVLMVLFILYFIFVHG"
     gene            complement(25746..26135)
                     /locus_tag="RPH49_000430"
     CDS             complement(25746..26135)
                     /locus_tag="RPH49_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123622.1"
                     /translation="MKNGPKLSLALIGIFLILCEFFYGIPFLGATFILSFGWQPLLFN
                     ALLYLILTIILLVNRQNAIRPIAIIPIFGIVGSFLAIIPFLGILIHWILFFLMILFVL
                     VVLSAPTYIPNKNARVIYTQYKDGHRE"
     gene            26492..26800
                     /gene="rpsJ"
                     /locus_tag="RPH49_000431"
     CDS             26492..26800
                     /gene="rpsJ"
                     /locus_tag="RPH49_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDY5123623.1"
                     /translation="MAKQKIRIRLKAYDHRVIDQSAEKIVETAKRSGADVSGPIPLPT
                     EKSVYTIIRAVHKYKDSREQFEQRTHKRLIDIVNPTPKTVDALMGLNLPSGVDIEIKL
                     "
     gene            26828..27490
                     /gene="rplC"
                     /locus_tag="RPH49_000432"
     CDS             26828..27490
                     /gene="rplC"
                     /locus_tag="RPH49_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDY5123624.1"
                     /translation="MTKGILGRKIGMTQVFGENGELIPVTVVEAKENVVLQKKTVEVD
                     GYNAIQVGFEDKKAYKKDAKSNKYANKPAEGHAKKADAAPKRFIREFRNVDVDAYEVG
                     QEVSVDTFVAGDVIDVTGVSKGKGFQGAIKRHGQSRGPMSHGSHFHRAPGSVGMASDA
                     SRVFKGQKMPGRMGGNTVTVQNLEVVQVDTENKVILVKGNVPGPKKGLVEIRTSIKKG
                     NK"
     gene            27517..28140
                     /gene="rplD"
                     /locus_tag="RPH49_000433"
     CDS             27517..28140
                     /gene="rplD"
                     /locus_tag="RPH49_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDY5123625.1"
                     /translation="MANYDVLKLDGTKSGSIELSDAVFGIEPNNSVLFEAINLQRASL
                     RQGTHAVKNRSAVSGGGRKPWKQKGTGRARQGTIRAPQWRGGGIVFGPTPRSYAYKMP
                     KKMRRLALRSALSFKAQENGLTVVDAFNFEAPKTKEFKNVLSTLEQPKKVLVVTENED
                     VNVELSARNIPGVQVTTAQGLNVLDITNADSLVITEAAAKKVEEVLG"
     gene            28140..28415
                     /gene="rplW"
                     /locus_tag="RPH49_000434"
     CDS             28140..28415
                     /gene="rplW"
                     /locus_tag="RPH49_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002506966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDY5123626.1"
                     /translation="MEARDILKRPVITEKSSEAMAEDKYTFDVDTRVNKTQVKMAVEE
                     IFNVKVASVNIMNYKPKKKRMGRYQGYTNKRRKAIVTLKEGSIDLFN"
     gene            28448..29281
                     /gene="rplB"
                     /locus_tag="RPH49_000435"
     CDS             28448..29281
                     /gene="rplB"
                     /locus_tag="RPH49_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDY5123627.1"
                     /translation="MAIKKYKPITNGRRNMTSLDFAEITKTTPEKSLLKPLPKKAGRN
                     NQGKLTVRHHGGGHKRQYRVIDFKRNKDGINAKVDSIQYDPNRSANIALVVYADGEKR
                     YIIAPKGLEVGQIVESGAEADIKVGNALPLQNIPVGTVVHNIELKPGKGGQIARSAGA
                     SAQVLGKEGKYVLIRLRSGEVRMILSTCRATIGQVGNLQHELVNVGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGRAPIGRPSPMSPWGKPTLGKKTRRGKKSSDKLIVRGRKK
                     K"
     gene            29348..29626
                     /gene="rpsS"
                     /locus_tag="RPH49_000436"
     CDS             29348..29626
                     /gene="rpsS"
                     /locus_tag="RPH49_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDY5123628.1"
                     /translation="MARSIKKGPFVDEHLMKKVEAQEGSEKKQVIKTWSRRSTIFPNF
                     IGHTFAVYDGRKHVPVYVTEDMVGHKLGEFAPTRTFKGHVADDKKTRR"
     gene            29655..30008
                     /gene="rplV"
                     /locus_tag="RPH49_000437"
     CDS             29655..30008
                     /gene="rplV"
                     /locus_tag="RPH49_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDY5123629.1"
                     /translation="MEAKAVARTIRIAPRKVRLVLDLIRGKNVAEAIAILKLTNKASS
                     PVIEKVLMSALANAEHNYDMNTDELVVKEAYANEGPTLKRFRPRAQGRASAINKRTSH
                     ITIVVSDGKEEAKEA"
     gene            30032..30685
                     /gene="rpsC"
                     /locus_tag="RPH49_000438"
     CDS             30032..30685
                     /gene="rpsC"
                     /locus_tag="RPH49_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDY5123630.1"
                     /translation="MGQKINPIGLRVGIIRDWEAKWYAEKDFASLLHEDLKIRKFIDN
                     ELKEASVSHVEIERAANRINIAIHTGKPGMVIGKGGSEIEKLRNKLNALTDKKVHINV
                     IEIKKVDLDARLVAENIARQLENRASFRRVQKQAITRAMKLGAKGIKTQVSGRLGGAD
                     IARAEQYSEGTVPLHTLRADIDYAHAEADTTYGKLGVKVWIYRGEVLPTKNTSGGGK"
     gene            30688..31122
                     /gene="rplP"
                     /locus_tag="RPH49_000439"
     CDS             30688..31122
                     /gene="rplP"
                     /locus_tag="RPH49_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDY5123631.1"
                     /translation="MLLPKRVKYRRQHRPKTTGRSKGGNYVTFGEFGLQATTTSWITS
                     RQIESARIAMTRYMKRGGKVWIKIFPHTPYTKKPLEVRMGAGKGAVEGWIAVVKPGRI
                     LFEVAGVSEEVAREALRLASHKLPVKTKFVKREELGGETNES"
     gene            31112..31321
                     /gene="rpmC"
                     /locus_tag="RPH49_000440"
     CDS             31112..31321
                     /gene="rpmC"
                     /locus_tag="RPH49_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002509269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDY5123632.1"
                     /translation="MKAKEIRDLTTSEIEEQIKSSKEELFNLRFQLATGQLEETARIR
                     TVRKTIARLKTVAREREIEQSKANQ"
     gene            31345..31608
                     /gene="rpsQ"
                     /locus_tag="RPH49_000441"
     CDS             31345..31608
                     /gene="rpsQ"
                     /locus_tag="RPH49_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011983253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDY5123633.1"
                     /translation="MSERNDRKVYVGKVVSDKMDKTITVLVETYKTHKLYGKRVKYSK
                     KYKTHDENNSAKLGDIVKIQETRPLSATKRFRLVEIVEESVII"
     gene            31640..32008
                     /gene="rplN"
                     /locus_tag="RPH49_000442"
     CDS             31640..32008
                     /gene="rplN"
                     /locus_tag="RPH49_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDY5123634.1"
                     /translation="MIQQETRLKVADNSGAREVLTIKVLGGSGRKTANIGDVIVCTVK
                     NATPGGVVKKGDVVKAVIVRTKSGVRRNDGSYIKFDENACVIIRDDKGPRGTRIFGPV
                     ARELREGNFMKIVSLAPEVL"
     gene            32044..32361
                     /gene="rplX"
                     /locus_tag="RPH49_000443"
     CDS             32044..32361
                     /gene="rplX"
                     /locus_tag="RPH49_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDY5123635.1"
                     /translation="MHIKKGDNVKVIAGKDKGKEGKVIATLPKKDRVVVEGVNIMKKH
                     QKPTQLNPEGGILETEAAIHVSNVQLLDPKTNEPTRVGYKFVDGKKVRIAKKSGEEIK
                     SNN"
     gene            32388..32927
                     /gene="rplE"
                     /locus_tag="RPH49_000444"
     CDS             32388..32927
                     /gene="rplE"
                     /locus_tag="RPH49_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDY5123636.1"
                     /translation="MNRLKEKFNTEVTENLMKKFNYSSVMEVPKIDKIVVNMGVGDAV
                     QNSKVLDNAVEELELITGQKPLVTKAKKSIATFRLREGMPIGAKVTLRGERMYEFLDK
                     LISVSLPRVRDFQGVSKKAFDGRGNYTLGVKEQLIFPEIDYDKVSKVRGMDIVIVTTA
                     NTDEEARELLANFGMPFRK"
     gene            32950..33135
                     /locus_tag="RPH49_000445"
     CDS             32950..33135
                     /locus_tag="RPH49_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDY5123637.1"
                     /translation="MAKTSMVAKQQKKQKYAVREYTRCERCGRPHSVYRKFKLCRICF
                     RELAYKGQIPGVRKASW"
     gene            33167..33565
                     /gene="rpsH"
                     /locus_tag="RPH49_000446"
     CDS             33167..33565
                     /gene="rpsH"
                     /locus_tag="RPH49_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDY5123638.1"
                     /translation="MTMTDPIADMLTRVRNANMVRHEKLELPASNIKKEIAEILKSEG
                     FIKNVEYVEDDKQGVLRLFLKYGQNDERVITGLKRISKPGLRVYAKASEMPKVLNGLG
                     IALVSTSEGVITDKEARKRNVGGEIIAYVW"
     gene            33590..34126
                     /gene="rplF"
                     /locus_tag="RPH49_000447"
     CDS             33590..34126
                     /gene="rplF"
                     /locus_tag="RPH49_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDY5123639.1"
                     /translation="MSRVGKKIIDIPSDVTVTFDGNHVTVKGPKGELSRTLNERMTFK
                     QEENTIEVVRPSDSKEDRTNHGTTRALLNNMVQGVSQGYVKVLELVGVGYRAQMQGKD
                     LILNVGYSHPVEIKAEENITFSVEKNTVVKVEGISKEQVGALASNIRSVRPPEPYKGK
                     GIRYQGEYVRRKEGKTGK"
     gene            34157..34516
                     /gene="rplR"
                     /locus_tag="RPH49_000448"
     CDS             34157..34516
                     /gene="rplR"
                     /locus_tag="RPH49_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDY5123640.1"
                     /translation="MISKIDKNKVRLKRHARVRTNLSGTAEKPRLNVYRSNKHIYAQI
                     IDDNKGVTLAQASSKDSDIATTATKVELATKVGEAIAKKAADKGIKEIVFDRGGYLYH
                     GRVKALAEAARESGLEF"
     gene            34537..35037
                     /gene="rpsE"
                     /locus_tag="RPH49_000449"
     CDS             34537..35037
                     /gene="rpsE"
                     /locus_tag="RPH49_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016426364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDY5123641.1"
                     /translation="MARREEETKEFEERVVTINRVAKVVKGGRRFRFTALVVVGDKNG
                     RVGFGTGKAQEVPEAIKKAVEAAKKDLVVVPRVEGTTPHTITGRYGSGSVFMKPAAPG
                     TGVIAGGPVRAVLELAGITDILSKSLGSNTPINMVRATIDGLQNLKNAEDVAKLRGKT
                     VEELYN"
     gene            35054..35233
                     /gene="rpmD"
                     /locus_tag="RPH49_000450"
     CDS             35054..35233
                     /gene="rpmD"
                     /locus_tag="RPH49_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDY5123642.1"
                     /translation="MAKLQITLTRSVIGRPETQRKTVEALGLKKTNSSVVVEDNPAIR
                     GQINKVKHLVTVEEK"
     gene            35250..35690
                     /gene="rplO"
                     /locus_tag="RPH49_000451"
     CDS             35250..35690
                     /gene="rplO"
                     /locus_tag="RPH49_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDY5123643.1"
                     /translation="MKLHELKPAEGSRKERNRVGRGVATGNGKTSGRGHKGQKARSGG
                     GVRPGFEGGQLPLFRRLPKRGFTNINRKEYAIVNLDQLNKFEDGTEVTPALLVESGVV
                     KNEKSGIKILGNGSLDKKLTVKAHKFSASAAEAIDAKGGAHEVI"
     gene            35690..36982
                     /gene="secY"
                     /locus_tag="RPH49_000452"
     CDS             35690..36982
                     /gene="secY"
                     /locus_tag="RPH49_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDY5123644.1"
                     /translation="MIQTLVNFFRTKEVRNKIFFTLAMLVIFKIGTYIPAPGVNPAAF
                     DNPQGSQGATELLNTFGGGALKRFSIFAMGIVPYITASIVMQLLQMDIVPKFSEWAKQ
                     GEVGRRKLNNVTRYLAISLAFIQSIGMAFQFNNYLKGALIINQSIMSYLLIALVLTAG
                     TAFLIWLGDQITQFGVGNGISIIIFAGILSTLPASLIQFGQTAFVGQEDTSLAWLKVL
                     GLLVSLILLTVGAIYVLEAVRKIPIQYAKKQTAQRLGSQATYLPLKVNSAGVIPVIFA
                     MAFFLLPRTLTLFYPDKEWAQNIANAANPSSNVGMVVYIVLIILFTYFYAFVQVNPEK
                     MADNLKKQGSYVPGIRPGEQTKKYITKVLYRLTFVGSIFLAVISILPILATKFMGLPQ
                     SIQIGGTSLLIVIGVAIETMKSLEAQVSQKEYKGFGGR"
     gene            36999..37646
                     /locus_tag="RPH49_000453"
     CDS             36999..37646
                     /locus_tag="RPH49_000453"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDY5123645.1"
                     /translation="MNIILMGLPGAGKGTQASEIVKKFPIPHISTGDMFRKAIKEETE
                     LGKEAKSYMDRGELVPDEVTVGIVKERISEDDAKKGFLLDGFPRTIEQAEALNNIMSE
                     LDRNIDAVINIEVPEEELMNRLTGRRICESCGTTYHLVFNPPKVEGICDIDGGKLYQR
                     EDDNPETVANRLSVNIKQSKPILDFYDQKGVLKNIDGSKDISDVTKDVIDILDHL"
     gene            37839..38057
                     /gene="infA"
                     /locus_tag="RPH49_000454"
     CDS             37839..38057
                     /gene="infA"
                     /locus_tag="RPH49_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017185218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDY5123646.1"
                     /translation="MAKQDVIELEGTVLDTLPNAMFKVELENGHEILAHVSGKIRMNY
                     IRILPGDKVTVEMSPYDLTRGRITYRYK"
     gene            38089..38202
                     /gene="rpmJ"
                     /locus_tag="RPH49_000455"
     CDS             38089..38202
                     /gene="rpmJ"
                     /locus_tag="RPH49_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDY5123647.1"
                     /translation="MKVRPSVKPICEKCKVIKRKGKVMVICENPKHKQRQG"
     gene            38225..38590
                     /gene="rpsM"
                     /locus_tag="RPH49_000456"
     CDS             38225..38590
                     /gene="rpsM"
                     /locus_tag="RPH49_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDY5123648.1"
                     /translation="MARIAGVDIPREKRVVISLTYIYGIGTSTAQKILEEANVSADTR
                     VKDLTDDELGRIREVVDGYKVEGDLRRETNLNIKRLMEISSYRGIRHRRGLPVRGQKT
                     KNNARTRKGPVKTVANKKK"
     gene            38614..39003
                     /gene="rpsK"
                     /locus_tag="RPH49_000457"
     CDS             38614..39003
                     /gene="rpsK"
                     /locus_tag="RPH49_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016998822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDY5123649.1"
                     /translation="MARKQVSRKRRVKKNIENGVAHIRSTFNNTIVTITDEFGNALSW
                     SSAGALGFKGSKKSTPFAAQMASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQS
                     AGLEVTAIRDVTPVPHNGCRPPKRRRV"
     gene            39078..40022
                     /locus_tag="RPH49_000458"
     CDS             39078..40022
                     /locus_tag="RPH49_000458"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDY5123650.1"
                     /translation="MIEIEKPRIETIEISEDAKFGKFVVEPLERGYGTTLGNSLRRIL
                     LSSLPGAAVKYIEIEGVLHEFSAVDNVVEDVSTIIMNIKQLALKIYSEEDKTLEIDVR
                     DEGEVTASDITHDSDVEILNPELKIATVSKGGHLKIRLVANKGRGYALAEQNNTSDLP
                     IGVIPVDSLYSPVERVNYTVENTRVGQSSDFDKLTLDVWTNGSITPQESVSLAAKIMT
                     EHLNIFVGLTDEAQNAEIMIEKEEDQKEKVLEMSIEELDLSVRSYNCLKRAGINSVQE
                     LADKSEADMMKVRNLGRKSLEEVKYKLEDLGLGLRKED"
     gene            40039..40407
                     /gene="rplQ"
                     /locus_tag="RPH49_000459"
     CDS             40039..40407
                     /gene="rplQ"
                     /locus_tag="RPH49_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002450507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDY5123651.1"
                     /translation="MGYRKLGRTSDQRKAMLRDLATSLIISERIETTEARAKEVRSVV
                     EKLITLGKKGDLASRRNAAKTLRNVEILNEDETTQTALQKLFGEIAERYTERQGGYTR
                     ILKQGPRRGDGAESVIIELV"
     gene            40945..41754
                     /locus_tag="RPH49_000460"
     CDS             40945..41754
                     /locus_tag="RPH49_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDY5123652.1"
                     /translation="MEDKNSVIVFKNVSFQYQSDASFTLKDVSFNIPKGQWTSIVGHN
                     GSGKSTIAKLMIGIEKVKSGEIFYNNQAITDDNFEKLRKDIGIVFQNPDNQFVGSIVK
                     YDVAFGLENHAVPHDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIASVLALN
                     PSVIILDEATSMLDPDARQNLLDLVRKVKSEHNITIISITHDLSEAMEADHVIVMNKG
                     TVYKEGTAIEIFDHAEELTTIGLDLPFPIKINQMLGYQTSFLTYEGLVDQL"
     gene            41751..42611
                     /locus_tag="RPH49_000461"
     CDS             41751..42611
                     /locus_tag="RPH49_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HDY5123653.1"
                     /translation="MTIRFDNVSYTYQKGTPYQHQAIHDVNTEFEQGKYYAIVGQTGS
                     GKSTLIQNINALLKPTTGTVTVDDITITHKTKDKYIRPVRKRIGMVFQFPESQLFEDT
                     VEREMIFGPKNFKMNLDEAKNYAHRLLMDLGFSRDVMSQSPFQMSGGQMRKIAIVSIL
                     AMNPDIIVVDEPTAGLDPQSKRQVMRLLKSLQTDENKAIILISHDMNEVARYADEVIV
                     MKEGSIVSQTSPKELFKDKEKLADWHIGLPEIVQLQYDFEQKHQTKLKDIALTEEAFV
                     SLYKEWQHEK"
     gene            42601..43407
                     /locus_tag="RPH49_000462"
     CDS             42601..43407
                     /locus_tag="RPH49_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDY5123654.1"
                     /translation="MKNKLIIGRYLPINSFVHHLDPRAKLMFVFLFIILIFFCHSPLT
                     YLWVFALILFFMRLAKIQLWFLIKGLTPIFFFLIFTLMMHIFLTKGGYVLVEWHGITI
                     ETNGILEGLYISLRLIGIVMIATIMTLSTSPIDLTDAFERLLAPLKMFKLPVHQLSMI
                     MSIALRFIPTLMDELDKIILAQKSRGSEISSGNIATRIKSFIPLLVPLFISAFQRAEE
                     LAVAMEVRGYDANVQRTSYRQLKWQLRDTLSLIMIIPFAIILFVLKYSGV"
     gene            43412..44215
                     /gene="truA"
                     /locus_tag="RPH49_000463"
     CDS             43412..44215
                     /gene="truA"
                     /locus_tag="RPH49_000463"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDY5123655.1"
                     /translation="MRILVEIAYQGNNFLGFQIQQNGRTVQQQFEKLLQRMHKRHVRI
                     HPSSRTDRGVHAIQQYFHFDTELNIPMSQWQYAMNRTLPDDIYVNNVVTVDDDFHCRY
                     DCVGKRYRYKVYQAQHRDPFQSGLKTFIPETLDLDKMNRAAQQFIGTHDFTGFCSQKT
                     EVESKVRTLYQSEIVKTDDGFDYIVTGSGFLYNMVRVLVAFLIEVGKGRHEVSDVPKL
                     LESKNRKNVPFTAPAEGLYLEKIYLDENELLKDFGNDIKIHRKKSLQND"
     gene            44455..44892
                     /gene="rplM"
                     /locus_tag="RPH49_000464"
     CDS             44455..44892
                     /gene="rplM"
                     /locus_tag="RPH49_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDY5123656.1"
                     /translation="MRQTFMANESNIERKWYVIDAEGQTLGRLSSEVASILRGKNKAT
                     YTPHVDTGDYVIVINASKIEFTGNKETDKVYYRHSNHPGGIKSITAGELRRTNPERLI
                     ENSIKGMLPSTRLGEKQGKKLFVYGGAEHPHAAQQPENYELRG"
     gene            44906..45304
                     /gene="rpsI"
                     /locus_tag="RPH49_000465"
     CDS             44906..45304
                     /gene="rpsI"
                     /locus_tag="RPH49_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDY5123657.1"
                     /translation="MTLAQVEYRGTGRRKNSVARVRLVPGEGNITVNNRDVREYLPFE
                     SLILDLNQPFDVTETKGNYDVLVNVHGGGFTGQAQAIRHGIARALLEADPEYRGSLKR
                     AGLLTRDPRMKERKKPGLKAARRSPQFSKR"
     gene            45893..46072
                     /locus_tag="RPH49_000466"
     CDS             45893..46072
                     /locus_tag="RPH49_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123658.1"
                     /translation="MTEIVEFLSDGKLASRLEIQETMGLQKSYTSELIAELKKLEIIG
                     SEGRGPGTRYYLIRD"
     gene            46722..46904
                     /locus_tag="RPH49_000467"
     CDS             46722..46904
                     /locus_tag="RPH49_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123659.1"
                     /translation="MKDSIFWKKAFIPVYFIVAMLVFLLFRFYIKTDNFSMYLMIIFL
                     ICLGTASIIYNYKNNR"
     gene            complement(46886..47166)
                     /locus_tag="RPH49_000468"
                     /pseudo
     CDS             complement(46886..47166)
                     /locus_tag="RPH49_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500937.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            47399..49063
                     /gene="alsS"
                     /locus_tag="RPH49_000469"
     CDS             47399..49063
                     /gene="alsS"
                     /locus_tag="RPH49_000469"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDY5123660.1"
                     /translation="MTGKKYTAADMVIDTLKNNGVEYVFGIPGAKIDYLFNALIDDGP
                     ELIVTRHEQNAAMMAQGIGRLTGKPGVVLVTSGPGVSNLTTGLLTATSEGDPVLALGG
                     QVKRNDLLRLTHQSIDNAALLKYSSKYSEEVQDPESLSEVMTNAIRIATSGKNGASFI
                     SIPQDVISSPAESKAISLCQKPNLGVPSEQDINDVIEAIKNASFPVLLAGMRSSSADE
                     TNAIRKLVERTNLPVVETFQGAGLISRELENHFFGRVGLFRNQVGDELLRKSDLVVTI
                     GYDPIEYEASNWNKELDTQIINIDEVQAEITNYMQPKKELIGNIAKTIEMISDKVDEP
                     FINQQHLDELEQLRAHIDQETGIKATHEEGILHPVEIIESMQKVLTDETTVTVDVGSH
                     YIWMARNFRSYNPRHLLFSNGMQTLGVALPWAISAALVRPNTQVVSVAGDGGFLFSSQ
                     DLETAVRKNLNIIQLIWNDGKYNMVEFQEEMKYKRSSGVDFGPVDFVKYAESFGAKGL
                     RVTNQEELEAAIKEGYETDGPVLIDIPVNYKDNIKLSTNMLPDVFN"
     gene            49100..49804
                     /gene="budA"
                     /locus_tag="RPH49_000470"
     CDS             49100..49804
                     /gene="budA"
                     /locus_tag="RPH49_000470"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDY5123661.1"
                     /translation="MASVLYQHGTLGTLMAGLLKGTASINELLQHGDLGIATLTGSNG
                     EVIFLDGKAYHANEHKEFVELKGDELTPYATVTKFVADTSYETKDKSSEAVFAEIKEK
                     MLSENLFSAVKISGLFKKMHVRMMPAQEPPYTRLIDSARRQPEQTETYVKGSVVGFFT
                     PELFHGIGSAGFHVHFANDDRNFGGHVLDFEVEDVKVEIQNIETFEQHFPIHDEDFTN
                     ANIDYKDISDEIREAE"
     gene            complement(50183..50608)
                     /locus_tag="RPH49_000471"
     CDS             complement(50183..50608)
                     /locus_tag="RPH49_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAP domain-containing protein"
                     /protein_id="HDY5123662.1"
                     /translation="MKLKSFVTATLALGLLSTVGAALPSHEASADSNNGYKEMTMDGY
                     HTVPYTISVDGITALHRTYFVFPENKKVLYQEIDSKVKNELASQRGVTTEKINNAQTA
                     TYTLTLNDGNKKVVNLKKNDDAKNSIDPSTIKQIQIVVK"
     gene            50903..51718
                     /locus_tag="RPH49_000472"
     CDS             50903..51718
                     /locus_tag="RPH49_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIB family hydrolase"
                     /protein_id="HDY5123663.1"
                     /translation="MSKRLLLFDFDETYFKHNTNEEDLSHLREMEKLLEKLTNNNEVI
                     TAVLTGSTFQSVMDKMDQVNMTFKPLHIFSDLSSKMFTWNNGEYVESETYKKKVLSEP
                     FLFEDIEDILRHISAQYNVEFIPQRAFEGNETHYNFYFHSTGNHNNDRRILEALVRYA
                     NDQNYTARFSRSNPLAGDPENAYDIDFTPSNAGKLYATQFLMKKYNIPVKSILGFGDS
                     GNDEAYLSYLEHAYLMSNSRDEALKQKFRLTKYPYYQGITLHVKEFVEGKYDY"
     gene            complement(51951..53099)
                     /locus_tag="RPH49_000473"
     CDS             complement(51951..53099)
                     /locus_tag="RPH49_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001798742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDY5123664.1"
                     /translation="MYKKWINGQLSHIDYFQNRKRFKRHVFQNKILRKEITFNDKNKM
                     SEVKYLSNDGFCYLSYWYGDNENIVNIFYFDKNSKEVLNFKNNKAFHSYWLDKNLTSN
                     DVLILDGIGTYHKVENMQNNDIKKIFTIHTNHFMSPYSYGAEIKPEFRNMLLNLKELD
                     TLVVLTKEQKDDIIKQFGDYNNIKVIPNAISFEENLTQNIREKNSIIVLQRFVAMKNI
                     THIISAINIVRKKVKDVKLHIYGTGTQKENYTKLIKKLKLQDNVFIHDYAFDIRALYT
                     KTSLSVLTSDYEGLPMSLLEAMSYGVPVISYPINYGPKSIIQNNINGIITKKKDNINE
                     LAKKIIHVLKKETLISQFSENARTTIKTNFSYEAVSKKWIELIDEKSQ"
     gene            complement(53099..53467)
                     /locus_tag="RPH49_000474"
     CDS             complement(53099..53467)
                     /locus_tag="RPH49_000474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123665.1"
                     /translation="MTTYMLMYSIPEKAGGITSVMLNRSKLLAEKGYSCALLTLDDKN
                     YDPLRAKLTNSGRLHKQVKIVNLYEELKMLYDVENTEIENKNMQTFEKLNLLNQEGFY
                     IQKDEYEEKNMLDTLKITIT"
     gene            complement(53477..53755)
                     /locus_tag="RPH49_000475"
     CDS             complement(53477..53755)
                     /locus_tag="RPH49_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123666.1"
                     /translation="MTLNEYNYNNELILKLNKIEVQKNNEKISEVFKDYEILKPKIVF
                     NGSNPYLALNHIIVAEIENYSSLETFSKIYVDEDYYYNYGELIIKCKK"
     gene            54628..55482
                     /locus_tag="RPH49_000476"
     CDS             54628..55482
                     /locus_tag="RPH49_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M23 family metallopeptidase"
                     /protein_id="HDY5123667.1"
                     /translation="MNKTNFGDYLNKSKSRKIYKIFDQNLKREFSYWHFRKLFKSYTR
                     QSDVHELKVCTQNDGTMEQIWIDKANQFGVAVTWKDNSIIGFVMRPLINYDAIKNETT
                     LKYAVPTTDCYEVFWGGDNELYNYHYLYPHQRYAIDLVIKENHKTYKNKGKVNTDYFY
                     FGKDIIAPANGTVEKVANGVQDNSIGSTNESQFLGNYIVIKHAENEYSLIAHLQQYSI
                     IVNEGQNVKYGDIIGKVGNSGNSTEPHIHFQVMNDKNIEACTSLKIRFINNRELIKGD
                     VVCGLQGE"
     gene            complement(55542..57968)
                     /locus_tag="RPH49_000477"
     CDS             complement(55542..57968)
                     /locus_tag="RPH49_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide lyase 8 family protein"
                     /protein_id="HDY5123668.1"
                     /translation="MTYRMKKWQKISTITLLMAGVITFNDSEFRSVDKHQIAVADTNV
                     QTTDYEKLRNTWLNVNYGYNQYDENNDAMKKKFEATEKEATNLLSSMKTESDRKYLWE
                     NSKDLDTKSADMTRTYRNIEKIAEAMKHKNTKLNTPDNKNKVKDALEWLHKNAYGKEP
                     TDKVKELTENFKNKTSRNTNLNWWDYEIGTPRALTNTLILLNGDISSDEKKKYTAPIK
                     TFAPESDKILSSVGQPEQAKGGNLVDIAKVKLLESIIEEDTTMMKESIDAFNKVFTYV
                     QSNATGKERNGFYKDGSYIDHQDVPYTGAYGVVLLEGISQMMPMIKETSFKDSNQNDT
                     TLKSWIDEGFMPLIYKGEMMDLSRGRAISRENETSHSVSATVMKSLLRLSDAMDDSTK
                     AKYKQIVKTSVKSDSSYKQNDYLSSYSDISKMKSLMEDSTISTNDLTQQLKIYNDMDR
                     VTYHNKGLDFAFGLSMTSKNVARYESINNENLKGWHTGAGMSYLYNSDVKHYRDNFWA
                     TADMKRLAGTTTIENEEPKGTDVKKSSKTFVGGTKFDDQHASIGMDFENQDKTLTAKK
                     SYFILNDKIVFLGTGIKSTDSSKNPVTTIENRKTNGYTLYTDDKQTTASDNQDTNSVF
                     LESTNKPKNNIGYHFLNKSKITVKKESHTGKWSDINKSQKSEDKTDEYYEVTQKHSDK
                     DNKYGYVLYPGITKDNFKSKASQVTVVKQDDDFHVVKDNESVWAGVNYSDSAKTFEIN
                     GTKVEVKAKGMFILKKKNDKTYECSFYNPESTNPASDIESKISMTGYSITNKDTSTTN
                     ESGVRFELTK"
     gene            complement(57965..58132)
                     /locus_tag="RPH49_000478"
     CDS             complement(57965..58132)
                     /locus_tag="RPH49_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123669.1"
                     /translation="MRKIWVIDCLYASTFFVDCLTVNSHLYTLTNFEKLNHYLIIIFI
                     AHAQHKKETCQ"
     gene            58376..58792
                     /locus_tag="RPH49_000479"
     CDS             58376..58792
                     /locus_tag="RPH49_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDY5123670.1"
                     /translation="MKTKEVVALMNISQDTLRYYEKVGVIPPVNRDENGYRIYNDSDL
                     NWIYLVKNLRNAGVSIESLIEFCRLAQLPKNENIQAQQKQILNKQLEELNENLKTIHD
                     ARDLLQYKIDNYDNHIAKINASDNHDANVERLWERK"
     gene            58862..59710
                     /locus_tag="RPH49_000480"
     CDS             58862..59710
                     /locus_tag="RPH49_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDY5123671.1"
                     /translation="MNHIEISKDVKIPVLGFGVFQIPQEQTAEAVKEAIKAGYRHIDT
                     AQSYLNETEVGQGIEASGIDRSELFITTKVWIENVNYEDTIKSIERSLQRLNLDYLDL
                     VLIHQPYNDVYGSWRALEELKENGKIKAIGVSNFGVDRIVDLGIHNQIQPQVNQIEIN
                     PFHQQEEQVAALQQENVVVEAWAPFAEGKNQLFQNQLLQAIADKYNKSIAQVILRWLV
                     ERDIVVLAKSVNPERMAQNLDIFDFELTEEDKQQIATLEESNSQFFSHADPEMIKALT
                     SRELDV"
     gene            59930..60055
                     /locus_tag="RPH49_000481"
     CDS             59930..60055
                     /locus_tag="RPH49_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123672.1"
                     /translation="MTYIPFSIITLITGIIMHMTMYFVKFECWKMPLFMKIIFTI"
     gene            60318..>60522
                     /locus_tag="RPH49_000482"
     CDS             60318..>60522
                     /locus_tag="RPH49_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123673.1"
                     /translation="MCFDINNLNIKKLNFRKVKNAIHLSLSGDKYQFLEDGKTINNTY
                     FLAVYDNAINIFEDLFSPSDSINL"
BASE COUNT        21595 a         8986 c        11188 g        18753 t
ORIGIN      
        1 taaatattta ataattgggg gtatttcgta atgaaaatga aacgttttat agctattgta
       61 atggcattat ttttagtatt agctggttgt tctaattcta atgataatca agacaacaaa
      121 aaagatgcaa cagacaatgg aaaaaaacaa gaaattcaag ttgcagcggc agcaagttta
      181 acagatgtaa ccaagaaatt agcttcagaa tttaaaaaag agcataaaaa tgctgatatt
      241 aaatttaact atggtggatc aggggcatta agaaaacaaa ttgaatcagg cgcacctgtt
      301 gacgtattta tgtctgcaaa tactaaagat gtagatgcat taaaagacaa gaataaagca
      361 cataatacat ataaatatgc gaaaaatagt ctagtactaa ttggtgataa agattcaaat
      421 tacacttcag taaaagactt aaaaggcaat gataaattag cattaggtga agtgaaaact
      481 gtaccagcag gaaaatatgc gaaacagtat ttagataaca ataacttatt taaagaagtt
      541 gaaagtaaaa tcgtttatgc taaagatgta aaacaagtat taaattatgt tgaaaagggt
      601 aatgcgaaac aaggttttgt atataaaact gacttatata aacaaaacaa aaaaattgat
      661 actgtaaaag taattaaaga agtagaactt aagaaaccaa tcacatacga agctggtgct
      721 acatcggata gtaaattagc aaaagagtgg atggaattct taaaatcaga taaagctaaa
      781 gaaatattaa aagaatacca ctttgcagca taaggagttg taatccatgc ctgacttaac
      841 acctttttgg atatccatac gagttgctgt aatcagtacg attattgtaa cggttttagg
      901 tatttttata tctaaatggt tgtatcgtcg taagggttcg tgggttaaag tattggaaag
      961 tttattgata ttacctattg ttttgccgcc aacggtatta ggttttattc tattaatcat
     1021 cttctcgcca agaggaccaa tcggtcaatt ctttgcgaat gtactacatt tacctgtagt
     1081 gttcactttg acaggtgctg tgatagcatc tgtcattgtt agttttccac taatgtatca
     1141 acatactgtg caaggcttca gaggtataga cacgaaaatg attaatacag ctagaacaat
     1201 gggagcaagt gaaacgaaaa ttttcctcaa attaatttta ccattagcta aacgctctat
     1261 tttagcaggt ataatgatga gttttgctcg tgcattaggt gagtttggtg ctacattaat
     1321 ggttgcagga tatattccaa ataaaacgaa tacactacct ttagaaatat actttttagt
     1381 ggaacaaggt agagaaaatg aagcgtggtt atgggtatta gtgctagtcg cattctctat
     1441 tgtggttata tctacaatta atttattgaa taaagataaa tataaggagg tcgactagat
     1501 gcttaaaatc aatgtgaaat atcaattaaa gaacacttta attcgcatca atatagatga
     1561 tactgaacca aaaatttatg cagttcgtgg tccgtctggc attggtaaaa ctactgtttt
     1621 aaatatgatt gccggattac gtaaagcaga tgaagctatt atcgaagtga atgggcaatt
     1681 gcttactgat acggcaaaaa acgtgaatgt taaaattcaa caacgacgta ttggatatct
     1741 gtttcaagac taccaattgt ttcctaatat gacggtctat aaaaatatta cttttatggc
     1801 tgaaccatct gaacacatcg atcaattaat ccaaacttta aacattgatc atttgatgaa
     1861 acaatatcct atgacattgt caggtggaga ggcacaacgt gtagcacttg cacgtgcact
     1921 tagcacgaaa ccagatttaa ttttattaga tgaacctttt tctagtttgg atgatactac
     1981 aaaagatgag agtattacat tagttaaacg tattttcaac gaatggcaaa taccaatcat
     2041 atttgtgaca cattcaaact atgaagcaga acaaatggct catgaaatta ttacaattgg
     2101 gtaatcattt atttgccatt aaagagttta gaacgtattt aaaattgtag aagtgaatgc
     2161 ttctatcagc attttaatga tgttttaaac tcttttttag gggcagtttt ttgagagaca
     2221 ttgacgcgcg tcatataatg aaagtaatga taaaaagaaa ggataactta atgtgagtca
     2281 agaacgttat tcaaggcaaa ttttatttaa acaaataggt gaaataggtc aaagcaaaat
     2341 aaatcaaaaa tgtgcgttga ttattggtat gggcgcatta ggtacacatg tggccgaagg
     2401 acttgttaga gcaggcattg ctaaactaat cattgttgat agagattata ttgaatttag
     2461 taatttacaa agacaaacat tgtttactga agaagatgct ttgaaaatga tgcctaaagt
     2521 ggttgcagct aaaaagcatt tgctagcgtt acgtagtgat gttgatattg atgattatat
     2581 tgcccatgtg gattattatt ttttggaaac acatggacag gacgttgacg ttattattga
     2641 tgcaaccgat aactttgaaa cacgacaact gattaatgat tttgcatata aacatcgtat
     2701 accttggatt tatggtggtg ttgtacagag tacatataca gaagctgcat ttatacctgg
     2761 taaaacacct tgctttaact gtttggtacc acaattgcca gcattaaatt taacatgtga
     2821 tacagtaggg gtcattcaac ctgccgtgac gatggcaaca agtttacaat taagagatgc
     2881 gatgaaagta ttaacggaac aaccaattga cacaaaaata acttatggcg atatttggga
     2941 aggtagtcat tattcatttg gtttcagtaa aatgcaacgt tcagactgta caacttgtgg
     3001 agatgtacca agttatccgt atttaaacaa gaatgaacaa cgttatgcaa cattgtgtgg
     3061 tagagacact gtacagtatg aaaatgcatc aattacacac gacattcttg ttcaattttt
     3121 aaaacaacat caactaaatt atcgcagtaa ttcgtatatg gttatgtttg aatttaaagg
     3181 acaccgcatt gttgctttta aaggtggaag gtttttaata catggcatga cacgcacatc
     3241 agatgccaca catctaatga atttattgtt tggataaaaa aagataagac aaaaggagtg
     3301 taatattatg ggcgaacatc aaaacgttaa attgaatcgt acagttaaag cagccgtact
     3361 aacggtatca gatactagag acattgatac agataaaggt ggtcaatgcg tgcgccaact
     3421 attacaagca gatgacgttg aagtgagtga cgcacattat acaattgtga aagatgaaaa
     3481 agtagccatc acgacgcagg taaagaagtg gttagaagaa gatattgatg tcatcattac
     3541 gactggtgga acaggtattg cacaacgtga tgtgacgatt gaagcagtaa aaccactttt
     3601 aactaaagag atagaaggct ttggggaatt gtttagatat ttgagttatg ttgaagatgt
     3661 tggcacgcgt gcattattgt ctcgtgctgt agcaggtaca gttaataata aattgatatt
     3721 ttcgattcca ggatcaacag gcgcagttaa attagcatta gaaaagctca ttaaaccaga
     3781 attaaatcat ctgattcatg agcttacaaa ataatttatt gatttgattg gcgttgaaaa
     3841 tctccagatt taccgccaga cttgctttca aggtaggttt cgccaataat cataccttta
     3901 tcaactgctt tcgtcatgtc gtaaatggtt aaagccgttg ctgatgcagc ggttaaagct
     3961 tccatttcaa caccggtttt gccagttgta gagacagttg tttgaatgtt taaagtataa
     4021 aggggtgcat ttgtttcatc ccagctgaag tgaacatcta tgccagtcaa tggcaatgga
     4081 tggcacatcg gaataattgt tgatgtattt ttagcagcca taataccagc gatttgagca
     4141 gtgttcaata cattgccttt ggtattggtg ttattagaaa tctgcttaaa aatagtttca
     4201 ttcacagtaa tgcttgaatg agcgacagca gttctttttg taatttgttt gtctgataca
     4261 tcgaccattt tggcgtggcc ttgttgatta atatgagtaa actcagtcat tttacccctc
     4321 ctagtgcatc tagtatatca tgaaaaaata aaagttttgg agatgatttt taatggtagt
     4381 agaaaaaaga aacccaatcc cagttaaaga agcaattcaa cgtatcgtta atcagcagag
     4441 ttcaatgccg gcaattacgg tagcacttga aaaaagtcta aatcatatct tagcagaaga
     4501 tattgtagct acttatgata taccaaggtt tgataaatca ccttatgatg gttttgcaat
     4561 tcgcagtgtt gattcacaag gggcaagtgg tcagaatcgc attgagttta aagtgattga
     4621 tcatattggt gcaggttcag tttctgataa attagttggg gatcacgaag cggtgcgtat
     4681 tatgactgga gcacaaatac ctaatggcgc agatgctgtt gttatgtttg aacaaacgat
     4741 tgaactagaa gatacattta caattcgtaa accattttca aaaaatgaaa atatatcttt
     4801 aaaaggtgaa gaaacaacga caggcgatgt tgttctaaaa aaaggacaag taattaatcc
     4861 aggggctatt gcggtccttg caacatatgg ctatgcagag gttaaagtta ttaagcaacc
     4921 gagcgtcgct gttattgcaa caggaagcga attattagat gttaatgatg tattagaaga
     4981 tggaaaaatt cgtaactcta atggtccaat gattcgtgcc ttagcagaaa aattaggtct
     5041 tgaagttggt atttacaaaa cacaacaaga tgatttagat agtggtatac aagtcgttaa
     5101 agaagctatg gaaaaacatg atatagttat tacaacgggc ggagtttctg tcggagactt
     5161 tgactattta cctgagattt ataaggctgt aaaggcggaa gtgttattta ataaagtagc
     5221 aatgcgtcct ggtagcgtaa caacggttgc atttgcagat ggaaaatatt tgtttggatt
     5281 atctggaaat ccatcagctt gttttacagg atttgaacta tttgtgaaac cagctgttaa
     5341 acatatgtgt ggcgcactag aagtcttccc gcaaataatt aaagcaacat taatggaaga
     5401 ttttaccaag gcaaacccat tcacacgatt tatacgtgct aaagcaacat taacaagtgc
     5461 tggagctact gtagtacctt caggattcaa taaatcaggt gcggttgtag cgattgcaca
     5521 tgctaactgt atggtcatgt taccaggagg gtcacgtggt tttaaagcgg ggcatacagt
     5581 agatattata ttgactgaat ctgacgctgc tgaagaggaa cttcttttat gattttacaa
     5641 attgtaggtt acaaaaagtc tggtaagaca acattgatga ggcatattgt ctctttctta
     5701 aagtcacatg gttatacagt tgctactatt aaacatcatg ggcatggtaa gaaagatatt
     5761 caattacagg attcagacgt cgatcacatg aagcattttg aagcgggggc agatcaaagt
     5821 attgtacaag gttttcaata tcagcaaact gtaacacgtg tagataatca aaatcttact
     5881 caaattattg aaaaatctgt tacaattgac accaatatcg tattagttga aggctttaaa
     5941 aatgctgatt ttgaaaaagt catagtctat cgaaatgaag aagagttgca agtattacaa
     6001 caattgtcga atgtttgtta tagcattaat gttagggagc atgaagattt tacagcattt
     6061 gagcaatggt tattaaataa aattaaaaat gattgtgata cacaattaac atagaggatt
     6121 gaaatgaatg aaacaatttg aaatcgtgac agaaccgata caaacagaac aatatcgtga
     6181 attcactata aatgaatatc aaggtgcagt agttgttttt accggtcatg ttcgcgaatg
     6241 gactaaaggc gtcaaaacgg aatatttaga atatgaagcg tatattccaa tggctgaaaa
     6301 gaaattggca caaattggag atgaaataaa tgaaaaatgg cctggaacga taacgagtat
     6361 tgttcataga atagggccat tacaaatttc agatatcgct gtattaattg caatttcttc
     6421 accgcatcgt aaagatgcct atcgagcaaa tgaatatgca attgagcgta taaaagaaat
     6481 tgttccgatt tggaaaaaag aaatttggga agatggttca aaatggcaag ggcatcaaaa
     6541 agggaattat gaagaagcga agagggagga ataagagaga tgaaggtact ttacttcgca
     6601 gaaattaaag atatattaca aaaagcacag gaagatattg tgcttgaaca agcattgact
     6661 gtacaacaat ttgaagattt attgtttgaa cgttatccgc aaatcaataa taaaaagttt
     6721 caagttgctg taaatgagga atttgtacaa aaatcagatt tcattcaacc taatgatact
     6781 gttgcattaa ttccaccggt tagtggaggt taagcgagca tgaaagcaat aattcttgca
     6841 ggtggtcatt cagtacgatt tggtaagccc aaagcttttg cggaagtgaa cggtgagacc
     6901 ttttatagta gagtaattaa gacattagaa tcaacaaata tgttcaatga aattattatt
     6961 agtacaaatg cgcaattggc aacgcaattt caatatccaa atgttgttat agatgatgag
     7021 aatcataatg ataaaggtcc attagcagga atttatacaa tcatgaagca acatcctgaa
     7081 gaagaattgt tttttgtcgt ttctgttgat acaccaatga ttactggtaa agctgtaagc
     7141 acgttgtatc agtttttagt ttctcatctt attgaaaatc atttagatgt cgcagctttt
     7201 aaagaagatg gacgttttat tccaacaatt gcattttata gtccgaatgc attaggcgct
     7261 ataactaaag cactacattc tgataattac agttttaaaa atgtatatca tgaattatca
     7321 acggattatt tggatgtcag ggatgtagat gcgccctcat attggtacaa aaatataaat
     7381 tatcagcatg atttggacgc tttaattcaa aaattgtaag ccgttaggag gtccacaaat
     7441 ggtagaacaa ataaaagata aactaggacg tcccatccgt gacttacggt tatctgtgac
     7501 agatcggtgt aactttaggt gtgattattg catgcctaaa gaggtatttg gagatgattt
     7561 cgtattttta cctaaaaatg aactgttaac gtttgatgaa atggctagaa tcgctaaggt
     7621 atatgcagaa ttaggtgtaa aaaaaatacg cattacaggt ggagaaccat tgatgcgacg
     7681 cgatttagat gtacttatag ctaaattaaa tcaaatcgat ggtattgaag atattggttt
     7741 gactacaaat ggtttgttat taaaaaagca tggacaaaag ttatatgatg ctgggctacg
     7801 cagaattaat gtcagtttgg atgctattga tgatacgcta tttcaatcaa tcaataatcg
     7861 taatattaaa gcgactacga ttttagaaca aattgattac gcgacgtcta ttggtttgaa
     7921 tgtaaaagta aatgttgtta tacaaaaagg tattaacgat gatcaaatta taccaatgct
     7981 tgaatatttt aaagataaac atatagagat tcgatttata gaatttatgg atgttggtaa
     8041 tgataatgga tgggatttca gcaaagttgt aactaaagat gaaatgctta ctatgataga
     8101 gcagcacttt gaaatcgatc gtgtagaacc aaaatatttt ggggaagtag caaaatatta
     8161 tcgccataag gataatggtg ttcaatttgg tttgattaca agtgtttcac aatcattttg
     8221 ttctacatgt acacgggcaa ggctgtcatc agatgggaag ttttacggat gtttatttgc
     8281 aactgtcgat ggatttaacg ttaaagcgtt tattcgttct ggcgtgaccg acgaagagtt
     8341 aaaagaacaa tttaaagctc tatggcaaat aagagatgat cgatattcag atgagagaac
     8401 tgctcaaaca gttgacaatc gccaacgtaa aaagataaac atgaattata ttggtggtta
     8461 atgtgtagga accactatat attatatcat tagagattct ttaatatttc tgtcttactc
     8521 cctaaaatac aatattattt attaaagtaa aaacggtcat atctatgcca gatttaatag
     8581 aaatgatcgt ttttaatgtt tttacaaatt ggcggggccc caacacagaa gcagacgaaa
     8641 agtcagctta caataatgtg caagttgggg aacggggccc caacatagag aatttcaaaa
     8701 agaaattcta cagacaatgc aggttgggga acaacgaaat aaattttatg aaaatatcat
     8761 ttctatccca ctcttaagaa tcactacata ataaatcttt agtggttctt taacattgat
     8821 gtcacacccc atgtcattga gttgtaatat atctttttta ggtataaatg ttgtcgaata
     8881 aacaacaagt tgtccaaaag atataaatct aaacaagata tagccagcaa tttaatattt
     8941 gtaatagata aaatgctaag tttgatatat aataaattta agtaattgta taataatatg
     9001 aattacaaac atctaagaag aaacatagga ggcatcatat tatgagtaat aaagttcaac
     9061 gttttataga agcagaaagg gagttaagtc agttaaagca ctggttaaaa acaacacata
     9121 agatttcaat tgaagaattt gtagtacttt ttaaagtgta tgaagctgaa aagattagcg
     9181 gtaaagaatt gagggataca ttacattttg aaatgctatg ggatacaagt aaaatcgatt
     9241 tgattatccg taaaatctat aaaaaagagc ttatttctaa attgcgttct gaaacggatg
     9301 aaagacaagt attctatttc tatagtactt ctcaaaagaa attgttagat aaaattacta
     9361 aagaaataga agtgttaagc gttacaaact aaaaacttaa aaagcatgcc aatcagtaca
     9421 tcataattgc gtcttgggga cagacaaatg atgaatagag attggcatgc tttttatttt
     9481 tgaatataaa tatttagttc atggcatttc tagttacatg acgtccatga attaagaagt
     9541 aaacaagcat agtaatgatt gctaaagcgg ccataaagcc gaagatttca ctatatgaaa
     9601 acatatgagt aaataaccca aggaatgatg gaccgaagcc gacacctgca tctagaccaa
     9661 cgtaaaaagt agatgtcgcg ataccatatt taatcggagg tgagactttt atcgcaatag
     9721 attgcattgc agatgataaa tttccatacc ctaaacctag gcaagctcca gcaagtaata
     9781 ttaaccagct ttgatagctt gaaattaagc acacaaatga aaggaaaagc atgataaatg
     9841 ctgggtagac aataatattt tcatttttat catccatcaa tctaccagca ataggtctag
     9901 taattaacga tgctatagca tagcaaataa agaaatagct tgctgcagtt actaggtgtc
     9961 gctctaaagc aaatgcttgt aaataagtta ggatggacgc ataggtaacg ccaattaaaa
    10021 gcataattac agcaacagga atggcctctt ttgcaataaa ttgatgaata ctaaatcttg
    10081 gtttatcaat gacattagtt tcagttttat tatttgttac ttcaaaatca acttttataa
    10141 ataatgagat aatgagtccg agtatgccta atatgacaca aataataaac agtaaatcaa
    10201 ttgcgtattt tgtaataagt aacatgccta gaaatgggcc aatcgctgta cctaatacta
    10261 aacttaaaga aaataaactg atgccttcac tttttctatt aacaggggta acgtatgccg
    10321 caatagtacc tgttgcagtt gtcacaactg cagttgcgat accgtttatg agacgtacaa
    10381 agattaaaaa agctaaagat ccatcaataa aataaagtaa ttgcgtgata attaaagcaa
    10441 ttaaaccaat aaataataat cgtttaggtc cgatttgatt tacaaattta cctgtagcaa
    10501 atcgaccaat taaagacccg acaataaata gtcctacaac taatccggct aatgaatcgg
    10561 aagcgtcgaa agcttgctta ctatagccag caataactac aagtaacaaa tacatgcata
    10621 ggtatacgat aaagttgaca aaaaagttga ttgtaaaact tttggtgaaa ataggtgatt
    10681 tatttaatga gccttgatta gtcattgtgt gcctccttta ataatatttc atgaatttga
    10741 ttcatcacat ttatggtttc ttgcatttga tcttgcgaaa tgtttgtttt ggcaactact
    10801 gcttgttgga gcttttgtac atcaagacaa acaatctcat ataattcatg ccctttaggt
    10861 gttaaagtta aaaacttttg tcgtttatcc tctaaactgt tttctactgt tataaggtca
    10921 ttttctatta gagcttttaa agtttttctt gcagtaggct tttcaattgc acgtctatgt
    10981 gaaatttcaa tgagagtagt gggctgatgt ttagcgatat cgcgtaagat taaccattgg
    11041 ccataatata tattgtgttt ttctaaaatc ggctcggcta attttaaata ggggcgatat
    11101 attgttataa aactattgaa aaattcttgt gatagcatag tgacatctcc taagataaaa
    11161 tagttagctt agctaacctt ttttacaaca atagtaatta taaaacggga gcaattagaa
    11221 atcaatatat aattattaag agcaaaaata attatacttt gttaaaataa gcgtaattac
    11281 atgtaaatag ggggatacta atgatattga aatttgatca catcattcat tatatagatc
    11341 agttagatcg gtttagtttt ccaggagatg ttataaaatt acattcaggt gggtatcatc
    11401 ataaatatgg aacattcaat aaattaggtt atatcaatga aaattatatt gagctactag
    11461 atgtagaaaa taatgaaaag ttgaaaaaga tggcaaaaac gatagaaggt ggagtcgctt
    11521 ttgctactca aattgttcaa gagaagtatg agcaaggctt taaaaatatt tgtttgcgta
    11581 caaatgatat agaggcagtt aaaaataaac tacaaagtga gcaggttgaa gtagtagggc
    11641 cgattcaaat ggaaagagat acacataaag atggtaaggt aaagtggcaa ttgctttata
    11701 taatgaatca ggatgatgat gaaattaagc caccattttt tattcaatgg gaagaaagtg
    11761 attccatgcg tactaaaaaa ttgcaaaaat atattcaaaa acaattttca attgaaactg
    11821 ttattgtgaa aagtaaaaac cgatcacaaa cagtatcgaa ttggttgaaa tggtttgata
    11881 tggacattgt agaagagaat gaccattaca cagatttgat tttaaaaaat gatgatattt
    11941 attttagaat tgaagatggt aaagtttcaa aatatcattc ggttatcata aaagacgcac
    12001 aagcaacttc accatattca atttttatca gaggtgctat ttatcgcttt gaaccattag
    12061 tataaatata cgtaagtgct atgagcgaga atgcccatat gaataatggc aagcacaatg
    12121 gaaagaatcg ttaatatatt atttaatcgt gatgacttaa ttaaaatgaa aaagattgat
    12181 aatataaatg tgaaaaagat aagtataacc cgtaaactaa agtaattcac ggtgagaggt
    12241 tgactcaatg tcataatgat tgcaacgatg ttcataatta taaatagact taaaataatt
    12301 gttctcatat caaacacctc attgttagat tattgacatt ataacagggg tatttgtata
    12361 tgaacattaa tgtggttgct tgaggaaaaa tttattcatt gaagtcaagt tggttcattt
    12421 tagaaatgaa tatcgtgtta gatgatgaaa gtatattgaa gtataggtaa ctagttgaaa
    12481 agtattaatt gtacgataac attaaattta acacgaaaca tagatataaa atgatttaca
    12541 attaaaatgg gtaaatttga acttgctaaa ctattaattg gagcatggac atttcaaaaa
    12601 taagagttca aatcttacac aagctctgaa tcgacactat aagatacaaa ctgtataatt
    12661 aaaggtattg ttaaatagaa ggagatatca taaatcatgg aaaagatgca tatcactaat
    12721 caggaacatg acgcatttgt taaatctcac ccaaatggag atttattaca attaacgaaa
    12781 tgggcagaaa caaagaaatt aactggatgg tacgcgcgaa gaatcgctgt aggtcgtgac
    12841 ggtgaagttc agggtgttgc gcaattactt tttaaaaaag tacctaaatt accttatacg
    12901 ctatgttata tttcacgtgg ttttgttgtt gattatagta ataaagaggc gttaaatgca
    12961 ttgttagaca gtgcaaaaga aattgctaaa gctgagaaag cgtatgcaat taaaatcgat
    13021 cctgatgttg aagttgataa aggtacagat gctttgcaaa atttgaaagc gcttggtttt
    13081 aaacataaag gatttaaaga aggtttatca aaagactaca tccaaccacg tatgactatg
    13141 attacaccaa ttgataaaaa tgatgatgag ttattaaata gttttgaacg ccgaaatcgt
    13201 tcaaaagtgc gcttggcttt aaagcgaggt acgacagtgg aacgatctga tagagaaggt
    13261 ttaaaaacat ttgctgaatt aatgaaaatc actggggaac gcgatggctt cttaacgcgt
    13321 gatattagtt actttgaaaa tatttatgat gcgttgcatg aagatggaga tgctgaacta
    13381 tttttagtaa agttggaccc aaaagaaaat atagcgaaag taaatcaaga attgaatgaa
    13441 cttcatgccg aaatagctaa atggcagcag aagatggaaa catctgaaaa gcaagctaaa
    13501 aaagcgcaaa atatgattaa tgatgcgcaa aataaaattg ctaaaaatga agatttaaaa
    13561 cgagacctag aagctttaga aaaggaacat cctgaaggta tttatctttc tggtgcacta
    13621 ttaatgtttg ctggctcaaa atcatattac ttatatggtg cgtcttctaa tgaatttaga
    13681 gattttttac caaatcacca tatgcagtat acgatgatga agtatgcacg tgaacatggt
    13741 gcaacaactt acgatttcgg tggtacagat aatgatccag ataaagactc agaacattat
    13801 ggcttatggg catttaaaaa agtgtggggt acatacttaa gtgaaaagat tggtgaattt
    13861 gattatgtat tgaatcagcc attgtaccaa ttaattgagc aagttaaacc tcgtttaaca
    13921 aaagctaaaa ttaaaatatc tcgtaaatta aaacgaaaat agattaaaga ctgaaatctg
    13981 aacgctcata agactgtcat ttgcgttcag atttttttac acaatataga atggttgagt
    14041 aaaatatttt tgaatatagt gaaagagggg gaagtactgt gataaaaaag ctattacaat
    14101 tttctttggg gaataagttt gctatctttt taatggttgt tttagttgtc ttgggcggtg
    14161 tatacgcgag tgctaaattg aaattagaat tactaccaaa tgtacaaaat ccagttattt
    14221 cagttacaac aacaatgccg ggtgcaacgc cacaaagtac ccaagatgaa ataagtagta
    14281 aaattgacaa ccaagtaaga tcgttggcat atgtgaaaaa tgttaaaacg caatccatac
    14341 aaaatgcttc aattgtaaca gttgaatatg aaaataatac agatatggat aaagcagaag
    14401 aacagcttaa aaaagaaatc gataaaatta aatttaaaga tgaagttggt caaccagaat
    14461 taagacgtaa ttcgatggac gcttttccgg ttttagcata ttcattttca aataaagaga
    14521 atgacttgaa aaaagtaacg aaagtactga atgaacaatt aataccaaaa ttacaaacgg
    14581 tagatggtgt gcaaaatgcg caattaaacg ggcagacgaa ccgtgaaatc acccttaaat
    14641 ttaagcaaaa tgaacttgaa aaatatgggt tgactgctga tgatgtagaa aactatctaa
    14701 aaacggcaac aagaacaaca ccacttggat tgttccaatt tggtgataaa gataaatcaa
    14761 ttgttgttga tggtcaatat caatctgttg atgcttttaa aaacataaat attccattaa
    14821 cgttggcagg aggacaaggg caatctcaat ctcaaagtga caataaacaa aattcagcca
    14881 tgtcagacgt taatcaggca tcaccacagc aaaattcaaa agcgtcatca tcaaataata
    14941 taagtggtgt gccgacagcg aaactaggag atttagctga tattacagtt ggtgatgtgc
    15001 gtacttctat ttctaaaacg aatggcaagg atgcggttaa tttacaaata actaaagctc
    15061 aagatgccaa tacagttcaa gtagccaaag atgtacaacg taaaattgat acattcgttg
    15121 atgaaaataa agattttaat gtcacaaaaa caatggatac tgcaaagcct gttgagaaat
    15181 cactttatac gatggttgaa aaagcatcat taggtacaat cgtggcaatt atagttattt
    15241 tgctgttttt aagaaacatt cgtacgacgg caatttctat tatatccatt ccgttatcac
    15301 ttcttatggc gcttattgct ctgaaattga gtgatgtttc attgaatata ctaacgttag
    15361 gtgcattaac agtagcgatt ggacgtgtga tagacgattc gattgtagtt gttgaaaata
    15421 tttatcgacg cttaacagat tcagaagaac aactaaaagg tgaaaattta attatcagtg
    15481 cgacaactga agtatttaaa ccaataatgt catcgacact agttactatt atcgtcttct
    15541 taccacttgt gtttgtatca ggttcagtag gcgaaatgtt tagacctttt gcattggcta
    15601 ttgcatttag tttattagca tcgttattag tgtcaattac actcgttcca gcgttggcag
    15661 caacactatt taaaaaaggc gttaaacgtc gtaataaaca acatcaagaa ggattaggtg
    15721 ttgttagtac aacttataaa aaagtattgc attggtcact aaatcataag tggattgtaa
    15781 ttatattaag tacattaatt ttggttgtaa ctattgtatt tggaggaccg agactaggca
    15841 ctagctttat ttcagcaggt gacgataaat ttttagctat tacttataca ccgaagcctg
    15901 gtgaaacgga gcaagcagtg ttgaatcatg cgaaagatgt tgaaaaatat ttaaaacaga
    15961 aaaagcatgt aaaaacaatt caatactcag ttggtggtag tagtccagta gatccaacgg
    16021 gtagtacaaa tagtatggca atcatggttg aatatgataa tgacacgcct aattttgatg
    16081 tagaagcgga taaggttatt aaacatgcag atggctttaa acatcctgga gagtggaaaa
    16141 atcaagattt aggaacaggt gcaggtaata aatctgtaga ggttactgtg aaaggcccat
    16201 caatggatgc cataaaatca actgtaaaag atattgaaca gaaaatgaaa caggttaaag
    16261 gactagccaa tgtcaaatct gatttatcgc aaacatatga tcagtatgaa attaaagttg
    16321 atcaaaataa agcggcagaa aatggtattt ctgcaagtca acttgcaatg cacttgaatg
    16381 aaaacttacc agaaaaaaca gttacgactg ttaaagaaaa tggtaaaact gttgatgtta
    16441 aagtcaaaca aaataagcaa acagactggt cagaagataa gttgaataat ataactttga
    16501 aaaagccgac tggtggcacg attaaattgg gagatatcgc tacgttagtt aaaacaacga
    16561 caccaagtaa attgacgcaa gaacaaggtg attatgcaac gacggtatct gctgaagtaa
    16621 caaataaaga tgtgggtggc acaacacgac aagtgatgtc taaaataaat aatttggaca
    16681 aaccgaataa tgtaaaggtt aatatcggtg gtgcatcaga tgatattaac aatgcaatga
    16741 cacaattagc ctttgcaatg ttagctgcga tcattatcgt atatttaatc ctagttatta
    16801 catttaaagg tggcttagca ccatttacaa ttctattctc tttaccattt acagttatcg
    16861 gtgtaattat tgcactatta atcacaggag aaacaatatc agtaccaagt ttaattggta
    16921 tgctaatgtt aattggaatc gtagtaacaa atgccattgt gttaatagac cgtgtcatta
    16981 ataatgagca gcagggcatg gagatgaaag aagcattaat cgaagcaggc ggtactagaa
    17041 ttagaccgat attaatgacg gcgattgcaa caattggtgc attagttcct ttgttatttg
    17101 gtcaagatag ctcgattctt atttcgaaag gattagctgc tacagttatt ggtggtttaa
    17161 tttcatcaac tttattaaca cttgtagttg taccagtaat atatgaaatt ctctttactt
    17221 taaaaaaacg attcactaaa cgatagataa tataaaagcc ataaaagcgg tcatggtatt
    17281 gactactttt atggcttttt aaaatttgaa attttagacc ttatttcacg tgcgatttaa
    17341 tcgatgtgtt aataaaacaa tactggcatt caacatgtaa tccgataata aaataagatt
    17401 gcaattatgt tattgcatgt tttgtttatt acttagaata atacgatggt taagatgaaa
    17461 tatatgacaa agataaataa tgacattaaa ttcaagatgt ttacgccttt tagatctttt
    17521 ttaagcattt taaatcctgt cacttcgaca ttaccgacta agagtaataa gacgataaat
    17581 acccaccaat tctcttttgg aaaactcatc gtcgttaatg ctaagacgaa taataacaac
    17641 acacccataa taattctcaa aatgcgagta aatacaactt ccattttaaa aatactaata
    17701 aaactaacaa ttagataaag tattgctagt aaaatcagat aaaattgcat atgataactt
    17761 cctctccgtt tcaaagggtt catgtagtac agcagcgtag aaaacataaa tagcagtgtt
    17821 gggatagata tgcgcgtatg ttattaatga gacactaaat cataacacga caacaccttg
    17881 tgattctaga tgtaattgag cgaaaaataa agcaattcat caatataacg tattcagagc
    17941 aatgctagtc aaatttatgt aactaaaagt atttattgcc tgaatgatag attattaatc
    18001 ttgcatttga gcacgaacat ttctaatttc attttcaata tctttaagtt gacgaacaag
    18061 tgcggaagta tctaaatcca aagattcccg tttttctaag tcgccttgaa gacgaacgta
    18121 atcatattta agttcggcta gttggttttc taaagacata ctataacact cctttgaaat
    18181 ataattaagt gcatttaatg tagattatag catgaaacag tagacttcta aaatatctgt
    18241 ggagtatgtt aaagttataa attatgaaga ttattgaaag aagggataac agtgacagaa
    18301 caatttacta tgattatttt attaattgcg cttggttact ttttgaagcg cattaatttt
    18361 ataaaggcaa ctgatagcca agtcattgct acattagttc ttaatgtcac actcccatct
    18421 ttagttattg tgaatttaaa cagtgcagaa ttaaaattgt cattctccat tttaccaatt
    18481 ttaatgatta tctatggtat tgtggcgaaa atgattgctg tctggttttt tagaaaatat
    18541 gataatcaca tgcgtggatc agtaggtatg atgactggtg ctatgaatat tggattgttt
    18601 gcatatccac taattgaagt gatatggcct aaaacggggc ttatttattt tggtatggct
    18661 gatataggtg gtgcctttgt gatgtttgga attacttact ttgtaggtag ctattttagt
    18721 gaaggtagtg atcaattcga ttttaaatat ttaggtaaga aattattaca atcagtgcca
    18781 ctcgttacat acattgtaat gtttatattg aatataagtc acatccattt accacatgtg
    18841 gcaatcgatt tctttagcat actttcccat gcaaatatgc cgttatcaat gattttgcta
    18901 ggtgtcatgt tgaattttac tctggaaaga aagtatatac ctgctactat taaatattta
    18961 tgtttgcatt atggattagc attagttggg ggattgttag tacatgtgtt gttaccggta
    19021 tcagatgata tgattaagac gacgttgttg gtcacttgga tgttcccagt tggtgtcgca
    19081 attatttctt atggtattca gtttaaatat cgaacactgt catttatagg tatgacgacc
    19141 aatttgacaa tcattattag tatcattatt ttgtacgtgt atcaggcagt gtttgtctag
    19201 tttacacatt tgaaaataaa atccatttta atagtcgaag aaaatgagag ccccctttac
    19261 cacaacatgt aaatgtatat tgtgaaaagg gggcttttat ttatgacata gttgttcaac
    19321 aggctgggac ataaatcaat attctatgct ctacgaagtt atattggcag tagttgactg
    19381 aatgaaaatg cgcttgtaac aagctttttt caattctagt caggggcccc aacaaagaga
    19441 aattggattc ccaatttcta cagacaatgc aagttggggt gtgggcccca acacagagaa
    19501 tttcgaaaag aaattctaca ggcaatgcga gttggggtgg gacgacgaaa tatattttgc
    19561 gaaaatatca tttctgtccc actccctatg cagctatcca cttcatatgt atggcgcata
    19621 cttgataaat gaatatcatc aagattttaa aagtatcgct aattttaaag tcttaaaacg
    19681 catgattaat gtcatgatgt gttattgtgt tttgttttta gagccacgta tttcctagga
    19741 aatatagagg aacattcaac gtaaaattct cgaaaattaa ttttaatcat tctataagtg
    19801 aatggttatt ttcagaagcg ataacatttt tactttacat gagtatttaa ctttctattt
    19861 caaattacct agaattatag cagctatcac gataataata atacctgccc aaatacccgt
    19921 catctgacga cgatcttttc tttctcctaa aatgaaaata ccgcctaagg ttgaaacgat
    19981 aacaagtaac tgtgataatg agaaacttgt agctacacca acttttggtt gagaatagaa
    20041 catgaacaag ttaccaattc cccaaatcac acctggcaat agattaagtg ctgttgattt
    20101 aagtgatgtt ttatgattca tggataggat aaagccacca attgccatac cgacagattg
    20161 gaagaacaat gcatcagttc caccaacacc aaagatgtca ccaagtacaa cgaaacctac
    20221 atatccaact gtagatacaa ttaaaatacc cattgctttt ttaaattcag gattatctga
    20281 ttgacgttca tttttagctt taagtgaagt aagtgctaca ccagtaacta ataatatcat
    20341 ggcgattaaa ccaaagataa tttgagtcat tgaagaccat tcacctaaaa agataacgct
    20401 gaataatgtt gtaccaacta attgcatacc tgtagaaact ggcatagtat ttgatacacc
    20461 gattaaacta atagatttaa gctgattcgc ttgtccaaac gcccataatg caccagaaat
    20521 aagaccgaca ataattacag taggattatt gaattttgcg aaaccagtaa taagtaaacc
    20581 taatccaaca atgagtgcgc ctagcgtcgt accacgaatt tggttgtaag gtccaccgcc
    20641 gacgaacaca ttaataagaa cgacacttcc ccagaataaa gcaggtaaaa gtgcgattaa
    20701 gaaatcaaga aattgcaaga ctactcactc tcctatacta tttatgcaag tgctcccctt
    20761 aattgacact tgcatgttat tgtaaagcat tctgccctaa tagtaaaaaa caactactta
    20821 taattttcaa tatttacaaa aagtagaaaa acccacaata catgctaatg atgtactgtt
    20881 gggtatttgc ttggtatttt attcagggat tgtttgatct tttacgttac gtgattcgaa
    20941 tttgaattta atgtactcat agttgatatg gaagcctaga ccattaaatc gttcgatgag
    21001 tttattattt ttattacgaa ttttaaaata aacttttcta atatcaaagt tatcaaaagc
    21061 atattgcaat gcatacgcaa gcaactcgaa agcgatacct ttcaaacggt aatctacatg
    21121 tgaactgaag tatttaatct cggcgattga ttgttgtgaa tcaatttcaa ggtataaata
    21181 acctttaagt aaaccttcgc taacaaataa aaacaaatga tgatggtcgt ctaaactatc
    21241 aatgatatct tgtggtgact gtgcctgata tttaaatgta gttgtgtgta atttgctgaa
    21301 agcacgataa aaccctttgt gataaggaat gatatttggt tggtgcatat cttcttctaa
    21361 tcttgtacgg gcttctatgt aatagtcagt gaagttataa cttgcttgaa taactttcat
    21421 taatggtttg tattgttgaa tgccttcttc aaaagaaaag ttaaagacgg catcgtcagg
    21481 ttggttcgaa gtcattgctt taaacagctt ttcaaacgta tcgacagata atacataatt
    21541 gtcagctacg aaagggccta tgactttgaa tttattttta tcgtatgcaa aagacaatat
    21601 gattgctttg attgaatcgt tttctttaat cgaaaataca ccaggtgatt caatcgcatc
    21661 ggttattaat acatctattt cattgtactg ttgaggaagt ttatataagt atgatgctga
    21721 ttcataattc gaatgttcaa tgaacgattt tatttgtgta atatcatata actgaactat
    21781 gctcatgtca ttacctccgt actttttgtt acttttatta tatagtattt caactgaaat
    21841 gaaagttaat agtgatatta acatgttaca atacatttaa cacatcattt gcaatcattg
    21901 aatttaaatc aaagattagt ggaatagatg aagcacgttc gaaataaaag aacgtatgag
    21961 aaaggataat ttatgaaatc tttaatatta gctgaaaaac catcagtcgc aagagatatt
    22021 gctgatgctt tacaaataaa tcagaagcgt aatggttact ttgaaaataa ccaatatatt
    22081 gtcacgtggg cgttaggtca tctagtgaca aatgcgacac ctgaacaata cgataaaaat
    22141 ttaaaggaat ggcgattaga agaccttcca attataccta aatatatgaa aactgttgtt
    22201 attggtaaaa caagcaaaca atttaaaaca gtaaaagcgt taattttaga taataaagtg
    22261 aaagatatta ttattgcaac agatgctgga cgagaaggtg aactagttgc aagattgatt
    22321 ttggataaag ttggtaacaa aaagccaatc cgtcgattat ggattagctc agttactaaa
    22381 aaagctattc aacaaggttt taaaaattta aaagacggtc gtcaatataa cgatttgtat
    22441 tatgcagcgt tagcgagaag tgaggcggat tggattgttg ggattaatgc aacgcgtgca
    22501 ctaacaacaa agtatgatgc acagctatcc ctgggacgtg ttcagacacc aacgattcaa
    22561 ttagtaaata cacgacaaca agagattaat cagttcaaac cacaacaata ctatacatta
    22621 tcattaacgg taaaagggtt tgattttcag ctagaatcaa atcagcgata taccaataaa
    22681 gaaactttag aacagatggt taataatttg aaaaatgtcg atggtaagat taaatctgtt
    22741 gctactaaac ataagaagtc gtatccgcaa tcactgtaca atttaacaga tttacaacaa
    22801 gatatgtata gacgttataa aattggacct aaagaaacat tgaatacact tcaaagttta
    22861 tatgagagac ataaagtcgt aacctatcca agaacagatt caaactattt aacaactgat
    22921 atggtagata ctatgaaaga acgtattcag gcgacgatgg caacaacata taaagaccaa
    22981 gcacgcccat taatgtctaa aacattttca tcaaaaatgt cgatatttaa taatcaaaaa
    23041 gtatctgatc accatgcaat tattcctaca gaagtgagac ctgtcatgtc agacttaagt
    23101 aatagagaac taaagttata cgatatgatt gtcgagcgtt ttttagaagc tttaatgcct
    23161 ccgcacgagt atgacgcgat aactgtaact ttagaggttg cagggcacac atttgttttg
    23221 aaagagaatg taacaactgt tttaggtttt aaatctatta gacaaggtga atctattaca
    23281 gagatgcaac agcctttttc agaaggcgat gaagtgaaga tttcaaaaac aaacattaga
    23341 gaacatgaaa caacacctcc agaatatttt aatgaaggtt cgttattaaa agcgatggag
    23401 aaccctcaga actttattca attgaaggat aaaaaatatg cgcaaacttt aaagcaaaca
    23461 ggtggtatcg gcacagttgc aacaagggcc gacattatcg ataaattatt taatatgaat
    23521 gctattgaat caagagacgg taaaattaaa gtaacgtcaa aaggtaaaca aatattagaa
    23581 ttagcaccag aagaattaac gtcgccactt ttaactgcac aatgggaaga aaaactactt
    23641 ttaattgaac gtggtaaata tcaggcgaaa acattcatta atgaaatgaa agattttacg
    23701 aaagatgttg taaatgggat taaaaatagt gatcgtaaat ataaacacga taatttaaca
    23761 accactgaat gcccaacgtg tggtaaattc atgattaaag ttaaaactaa aaatggtcag
    23821 atgcttgtgt gccaagatcc atcttgtaag acgaaaaaga atgtacagcg caaaacaaat
    23881 gcaagatgtc caaactgtaa aaagaaatta acgttgtttg gtaaagggaa agaagcggta
    23941 tatcgttgtg tttgtggaca ttctgaaacg caagcacata tggatcagcg tatgaagtct
    24001 aaatcctctg gtaaagtatc tcgtaaagaa atgaaaaagt atatgaataa aaatgaaggt
    24061 ttagacaata atccgtttaa agatgcatta aagaacttga atttatagat aaaatcgaac
    24121 aaagttgaat cagaaaaacg aaaagttcgc ttttggtatt gttttttatt aagaatgata
    24181 ttaaactatt aaggtatttt aaaaaaagga gcatccattc gtgaaaaact atttccagtt
    24241 cgataaatat ggaacaaact ttaaaagaga aatcttaggc ggtatcacaa ctttcttatc
    24301 tatggcctat attttagcag ttaacccgca agttttaagt ttagcaggtg ttaaaggcgt
    24361 atcagaagat atgaaaatgg accaaggtgc catttttgta gcgactgcat tagcagcatt
    24421 tgtaggctcg ctattcatgg gactaatagc taaatatcca attgcgttag caccaggtat
    24481 gggattaaat gcattctttg catttactgt tgtgttaacc atgggtattc cttggcaagt
    24541 tggtttaaca ggcgttttat tctcaggtat attctttgcg atattaaccg tcacagggtt
    24601 tagggaagtt attattaatg caattcctta tcaaatgaag atggctgttt cagcaggtat
    24661 aggattattc attacatttg taggtttaca aagttcgggt attatagtta aaaatgaatc
    24721 tacattagta acattgggac atttaactga tccaccagta cttttagcga tattcggtat
    24781 cgttattaca gttattttat atgcaattaa attgccgggt tctatcttta tcggtatgat
    24841 catcacagca atcgttggta tgttcactgg attgattcaa atgccatctg gtattgtagg
    24901 taagattcca agtattgaac caacgttcgg tgctgcattt gaagcgttta aagacccaag
    24961 tcaattatta acgatacagt tcttaattgt tattttaacg ttcttattta ttgatttctt
    25021 tgatacagct ggtacattag tagccgttgc tactcaagca ggtattatga aagataataa
    25081 attaccaaga gctggtagag cattgttctc agattcttta gctacgattg taggatcagt
    25141 ttttggaaca actacaacaa cttcttatat cgaatcaact tcaggtgttg ctgtaggtgc
    25201 tagaacagga tttgctagta tcgtaacagg ttgttgtttc ctattagcgc tgttctttag
    25261 tccgttaatc gctgttgtaa caagtgcagt tacgacacca gctttagtgg tggtaggtgt
    25321 attaatggct gcaaactttg ctgagataaa ctggaaaagt tttgaagttg cagtgccagc
    25381 attcattaca atcattatga tgcctttatc atactcaatt gcaactggta ttgcgtgtgg
    25441 atttattttc tatccaatta caatgcttat ctctaaaaaa cataaagaag tacatccgat
    25501 aatgtatgta ttaatggtac tattcattct gtacttcata tttgttcatg gttaaatcca
    25561 tacacaaaaa acgactgcca atgattggta gtcgtttttt ctttgaagta aggataaaat
    25621 aagaagcgaa ataacataaa gcaatattat gaatgtcttt aaatatccga tataaatata
    25681 cttcttttaa aattgttgga cgtgtttctt ctatattata tacctaatta aaaaggtttt
    25741 aagaattatt ctctatgtcc atctttgtat tgtgtgtaaa tgacacgagc atttttatta
    25801 ggtatatagg ttggcgctga taatacaact aggacaaata gaatcattag gaaaaataaa
    25861 atccaatgaa tcaaaattcc taagaagggg ataatagcta aaaaactacc tactatacca
    25921 aatattggaa taatcgctat aggtctaatc gcattttgtc tattcactaa taatataata
    25981 gtaagaatta gataaagtaa tgcattaaag agtaaaggct gccatccaaa acttaaaata
    26041 aacgttgcac ctaaaaaagg aatgccatag aaaaactcac aaagtattaa aaagatacct
    26101 ataagtgcta aagataattt tggtccattt ttcatattca ttcaccaccg ttcttatgac
    26161 taattatata gaataatttt caatgataat aataaaatga ttcaaggtac gaatttacaa
    26221 taaagaagga aataaaaaat atctcgaaaa tagttgaact gactaagtat ataaagtaaa
    26281 atataaaagt atgtgttaga cagatagaaa aattatgtga aaagccttga tttatcgatg
    26341 tttttcgtgt aatataacta acgttggact ttaagaaaag cgatgaagcg aaaggttact
    26401 gacacacccg gccgctttgc catggcgctg tgtaagatag ttttcgtgga gaagtctatc
    26461 actaaatgta gacgaataag gagggaaaat tatggcaaaa caaaaaatca gaatcagatt
    26521 aaaagcttat gatcaccgcg tgattgatca atcagcagag aagattgtag aaacagcgaa
    26581 acgttctggt gcagatgttt ctggaccaat tccgttacca actgagaaat cagtttacac
    26641 aatcatccgt gccgtgcata agtataaaga ttcacgtgaa caattcgaac aacgtacaca
    26701 caaacgttta atcgatattg taaacccaac accaaaaaca gttgacgctt taatgggctt
    26761 aaacttacca tctggtgtag acatcgaaat caaattataa tagacaattt taggaggtgg
    26821 actttcgatg accaaaggaa tcttaggaag aaaaattggg atgacacaag tattcggaga
    26881 aaacggtgaa ttaatccctg taacagtagt agaagctaaa gaaaatgttg tattacaaaa
    26941 gaaaactgta gaagttgatg gatacaacgc aatccaagtt ggatttgaag acaaaaaagc
    27001 atacaaaaaa gatgcaaaat ctaataaata tgctaataaa ccagctgaag gtcacgctaa
    27061 aaaagctgac gcagcaccta agcgcttcat tcgtgaattc cgcaatgtag acgtggatgc
    27121 ttacgaagta ggtcaagaag tctcagtaga tacttttgta gctggcgacg ttattgacgt
    27181 aacaggcgta tcaaaaggta aaggtttcca aggtgcaatt aaacgccacg gacaatctcg
    27241 tggacctatg tcacatggtt ctcatttcca cagagcacca ggttctgtag gtatggcttc
    27301 agatgcttct agagtattta aaggccaaaa aatgccagga cgtatgggtg gaaacacagt
    27361 aactgttcaa aacttagaag tagttcaagt tgacacagaa aacaaagtta tcttagtaaa
    27421 aggtaacgta cctggaccta aaaaaggttt agtagaaatc agaacttcaa ttaaaaaagg
    27481 taataaataa taagaagtga aaggaggaaa tgcataatgg ctaattatga tgttttaaaa
    27541 ttagacggaa ctaaatcagg ttcaatcgaa ttaagcgatg cagtattcgg tattgagcca
    27601 aataatagcg ttttattcga agctattaat ttacaacgtg cttcattacg tcaaggtacg
    27661 catgctgtta agaatcgttc agcagtaagc ggtggcggac gtaaaccatg gaagcaaaaa
    27721 ggaacaggtc gtgctcgtca aggtacaatc cgtgctccac aatggcgtgg cggtggtatc
    27781 gtattcggac caactccaag aagttatgca tacaaaatgc ctaagaaaat gcgtcgttta
    27841 gctttacgct cagcattatc tttcaaagct caagagaatg gcttaactgt agttgacgca
    27901 tttaacttcg aagctccaaa aactaaagaa ttcaaaaatg tattatctac attagaacaa
    27961 cctaaaaaag tattagtagt tactgaaaac gaagatgtaa atgttgaatt atcagcacgc
    28021 aacatccctg gcgttcaagt gacaactgct caaggtttaa atgttttaga tatcactaat
    28081 gctgacagct tagtaattac tgaagctgct gctaaaaaag ttgaggaggt gctcggataa
    28141 tggaagcaag agatattctt aagcgccccg taatcactga gaaatcttct gaagcaatgg
    28201 ctgaagacaa atacactttc gacgttgata ctcgtgttaa caaaacacaa gtaaaaatgg
    28261 cagttgaaga aatcttcaac gtaaaagttg caagtgttaa tatcatgaat tacaaaccta
    28321 agaaaaaacg tatgggccgt taccaaggct atacaaacaa aagaagaaaa gcgattgtaa
    28381 ctcttaaaga aggatcaatc gacttattta actaataaac caattaccat taaggaggta
    28441 agcgacaatg gctattaaaa agtataagcc aataacaaat ggtcgtcgta atatgacttc
    28501 gttagatttc gcagaaatca cgaaaactac acctgaaaag tcattattaa aaccgctacc
    28561 gaaaaaagcg ggacgtaaca accaaggtaa attgactgta agacaccatg gtggtggaca
    28621 caaacgtcaa taccgtgtta tcgatttcaa acgtaacaaa gatggtatca atgcaaaagt
    28681 tgattctatt caatatgatc caaaccgctc agcaaacatc gctttagttg tatatgcaga
    28741 cggtgaaaaa cgatatatca ttgctcctaa aggattagaa gtaggtcaaa tcgttgaaag
    28801 tggtgctgaa gctgacatca aagttggtaa cgcattacca ttacaaaaca ttccagttgg
    28861 tacagtagta cacaacatcg agcttaaacc tggtaaaggt ggacaaatcg ctcgttcagc
    28921 tggtgcaagt gctcaagtac ttggtaaaga aggtaagtac gtattaatca gattaagatc
    28981 tggtgaagtt cgtatgatct tatctacttg ccgtgctaca atcggtcaag ttggtaacct
    29041 acaacacgaa ttagttaacg ttggtaaagc cggacgttca agatggaaag gtattcgtcc
    29101 aacagttcgt ggttctgtaa tgaaccctaa cgatcaccca cacggtggtg gtgaaggtcg
    29161 tgctcctatc ggtagaccat ctccaatgtc accatggggt aaacctacgc ttggtaagaa
    29221 aactcgtcgt ggtaaaaaat catcagacaa acttatcgtt cgtggacgta agaaaaaata
    29281 atataatcaa cttatttggg tgtgcggctt aaagctgcac gcacataata agaagggagg
    29341 cgcccaaatg gctcgtagta ttaaaaaagg acctttcgtc gatgagcatt taatgaaaaa
    29401 agttgaagct caagaaggaa gcgaaaagaa acaagtaatc aaaacatggt cacgtcgttc
    29461 tacaattttc cctaatttca tcggacatac atttgcagta tacgacggac gtaaacacgt
    29521 acctgtatat gtaactgaag atatggtagg tcataaatta ggtgagtttg ctcctactcg
    29581 tacattcaaa ggacacgttg cagacgacaa gaaaacaaga agataatatc tattaagtag
    29641 aggaggacat cctaatggaa gcaaaagcgg ttgctagaac aataagaatc gcacctcgta
    29701 aagtaagact agttcttgac ttaatcagag gtaaaaatgt tgctgaagct attgcaattt
    29761 taaaattaac aaacaaagct tcatcaccag taattgaaaa agtattaatg tccgctttag
    29821 ctaatgctga acataactat gacatgaaca cagatgaatt agtagttaaa gaagcatatg
    29881 ctaacgaagg accaacatta aaacgtttcc gtccacgtgc gcaaggtcgt gcaagtgcga
    29941 ttaacaaacg tacaagccac attacaatcg tcgtaagtga cggtaaagaa gaagctaaag
    30001 aagcttaatt aacttttaag gagggaatac tgtgggtcaa aaaattaatc caatcggact
    30061 tcgtgttggt attatccgtg attgggaagc taaatggtat gctgaaaaag acttcgcttc
    30121 acttttacac gaagatttaa aaatccgtaa atttattgat aatgaattaa aagaagcatc
    30181 agtttctcac gtagagattg aacgtgctgc aaaccgtatc aacattgcaa ttcatactgg
    30241 taaacctggt atggtaattg gtaaaggcgg ttcagaaatc gaaaaattac gcaacaaatt
    30301 aaatgcgtta actgataaaa aagtacacat caacgtaatt gaaatcaaaa aagttgatct
    30361 tgacgctcgt ttagtagctg aaaacatcgc acgtcaatta gaaaaccgtg cttcattccg
    30421 tcgtgtacaa aaacaagcaa tcactagagc tatgaaactt ggtgctaaag gtatcaaaac
    30481 tcaagtatct ggtcgtttag gcggagctga catcgctcgt gctgaacaat attcagaagg
    30541 aactgttcca cttcatacgt tacgtgctga catcgattat gcacacgctg aagctgacac
    30601 tacttacggt aaattaggcg ttaaagtatg gatctatcgt ggagaagttc ttcctactaa
    30661 gaacactagt ggaggaggaa aataataatg ttactaccaa aacgtgtaaa atatcgtcgt
    30721 caacatcgtc ctaaaacaac tggtcgttct aaaggcggta actacgtaac atttggtgag
    30781 tttggtttac aagctacaac aacgtcttgg atcacatctc gtcaaatcga atctgctcgt
    30841 atagcaatga cacgttacat gaaacgtggc gggaaagttt ggattaaaat cttcccacat
    30901 acaccatata ctaaaaaacc tttagaagta cgtatgggtg ctggtaaagg tgcggttgaa
    30961 ggctggatcg cagttgttaa accaggtaga attttattcg aagttgctgg cgtttctgaa
    31021 gaagttgcgc gtgaagcact acgtttagca agtcacaaac ttccagtaaa aactaagttt
    31081 gtaaaacgtg aggaattggg tggtgaaaca aatgaaagct aaggaaatta gagacttaac
    31141 cacttcagaa atcgaagaac aaatcaaatc ttcaaaagaa gagcttttta acctacgctt
    31201 tcagttagct acaggtcaat tagaagaaac tgcacgtatt cgtacagtaa gaaaaacgat
    31261 tgcacgtcta aaaactgttg ctcgtgaaag agaaattgaa caaagtaagg ctaatcaata
    31321 attaagtaag aggaggttac aaaagtgagc gaaagaaacg atcgtaaagt ttatgtaggt
    31381 aaagttgttt cagacaaaat ggacaagact attacagtac ttgttgaaac ttacaaaaca
    31441 cacaaattat acggtaaacg agtaaaatac tctaaaaaat acaaaactca tgatgaaaac
    31501 aattcagcta aattaggaga cattgttaaa attcaagaaa ctcgtccttt atcagcaaca
    31561 aaacgttttc gtttagtaga gattgttgaa gagtcagtaa ttatttaata caagtttaga
    31621 gataagggag gtttaactaa tgatccaaca agaaacacgc ttgaaagtag cagacaactc
    31681 tggtgctcgt gaagttctta caatcaaagt attaggtgga tctggtcgta aaacagcaaa
    31741 catcggcgat gttatcgtat gtactgttaa aaatgcaaca ccaggtggcg ttgttaaaaa
    31801 aggtgacgtt gtcaaagctg taatcgtacg tactaagtca ggtgttcgtc gtaatgacgg
    31861 ttcatacatc aaatttgatg aaaatgcatg tgttatcatc cgtgatgaca aaggcccacg
    31921 tggtactcgt atcttcggac ctgttgctcg tgaattacgt gaaggtaact tcatgaaaat
    31981 cgtatcatta gcaccagaag tactttaatt aataacaacc aatacaaata aggaggtgcc
    32041 cacatgcata tcaaaaaagg tgacaacgtt aaagttatcg caggtaaaga caaaggtaaa
    32101 gaaggtaaag taattgctac tctacctaaa aaagaccgtg tcgttgtgga aggtgttaac
    32161 attatgaaaa aacaccaaaa accaactcaa ttaaatcctg aaggtggaat cttagaaaca
    32221 gaggcagcaa tccatgtttc taatgtacaa ttattggacc ctaaaacaaa cgaaccaact
    32281 cgtgtaggtt acaaatttgt tgatggtaaa aaagttcgta tcgctaaaaa atctggcgaa
    32341 gaaattaaat ctaataatta ataacaagtt gaaaggagga tcccactttg aaccgtttaa
    32401 aagaaaagtt taacactgaa gttactgaaa acttaatgaa aaaattcaat tatagttcag
    32461 taatggaagt accaaaaata gataaaatcg ttgtgaacat gggtgtaggt gacgcagtac
    32521 aaaattctaa agtattagac aatgctgttg aagaattaga attgatcact ggtcaaaaac
    32581 cattagtaac taaagctaaa aaatcaatcg cgactttccg tttacgtgaa ggtatgccaa
    32641 tcggtgcgaa agtaacactt cgcggtgaaa gaatgtatga attcttagac aaattaattt
    32701 cagtatcatt accacgtgta cgtgacttcc aaggtgtttc taaaaaagca tttgacggac
    32761 gcggtaacta cactttaggt gttaaagaac aattaatttt cccagaaatc gactatgata
    32821 aagtaagtaa agttagagga atggatattg ttatcgtaac gactgctaac actgatgaag
    32881 aagctcgtga attgttagct aacttcggta tgccattccg taaataatta tttaaaggag
    32941 gctaattaag tggctaaaac ttcaatggtt gctaagcaac aaaaaaaaca aaaatatgca
    33001 gttcgtgaat acactcgttg tgaacgttgt ggccgtccac attctgtata tcgtaaattt
    33061 aaattatgcc gtatttgttt ccgtgaatta gcttacaaag gccaaatccc tggcgttcgt
    33121 aaagctagct ggtaataaaa aagagtctga aaggaggcaa caatcaatga caatgacaga
    33181 tccaatcgca gatatgctta ctcgtgtaag aaacgcaaac atggtgcgtc acgagaagtt
    33241 agaattacct gcatcaaata ttaaaaaaga aattgctgaa atcttaaaga gtgaaggttt
    33301 cattaaaaat gttgaatacg tagaagatga taaacaaggt gtacttcgtt tattcttaaa
    33361 atatggtcaa aacgatgagc gtgttatcac aggattaaaa cgtatttcaa aaccaggttt
    33421 acgtgtttat gcaaaagcta gcgaaatgcc taaagtatta aatggtttag gtattgcatt
    33481 agtatcaact tctgaaggtg taatcactga caaagaagca agaaaacgta atgttggtgg
    33541 agaaattatc gcatacgttt ggtaataaaa aataaggagg tgccataaca tgagtcgtgt
    33601 tggtaagaaa attattgaca tccctagtga cgtaacagta acttttgatg gaaatcatgt
    33661 aactgttaaa ggtcctaaag gtgaattatc aagaacttta aatgaaagaa tgacattcaa
    33721 acaagaagaa aacacaattg aagttgtaag accatctgat tctaaagaag atagaacaaa
    33781 ccatggtaca actcgtgctt tattaaacaa tatggtacaa ggtgtttctc aaggatacgt
    33841 aaaagtactt gaacttgttg gtgtaggtta ccgtgctcaa atgcaaggta aagacttaat
    33901 ccttaacgtt ggttattctc acccagtaga aattaaagct gaagaaaaca ttactttctc
    33961 agttgagaaa aacacagtcg ttaaagttga aggtatttca aaagaacaag ttggagcatt
    34021 agcatctaac atccgttcag taagacctcc agaaccttac aaaggtaaag gtattcgtta
    34081 ccaaggtgaa tacgttcgcc gtaaagaagg taaaactggt aaataataga taaactctaa
    34141 agaaaggagt attgaaatga tcagtaaaat tgataaaaat aaagtgcgtt taaaaagaca
    34201 tgctcgtgtt cgtactaact tatcaggtac agctgaaaag ccacgtttaa acgtatatcg
    34261 ttcaaacaag catatctacg ctcaaattat tgatgataat aaaggcgtaa cattagctca
    34321 agcttcttca aaagacagcg acattgctac tacagcaact aaagttgaat tagcaactaa
    34381 agtcggtgaa gcaattgcta aaaaagctgc tgacaaaggc attaaagaaa tcgtatttga
    34441 ccgtggagga tatttatatc acggacgtgt taaagcatta gctgaagcag caagagaaag
    34501 cggattagaa ttttaattta aaggagggac aaatacatgg ctcgtagaga agaagagacg
    34561 aaagaatttg aagaacgcgt tgttacaatc aaccgtgtag caaaagttgt aaaaggtggt
    34621 cgtcgtttcc gtttcactgc attagttgta gttggagaca aaaatggtcg tgtaggtttc
    34681 ggtactggta aagctcaaga ggtaccagaa gcaatcaaaa aagctgttga agcagctaaa
    34741 aaagatttag tagttgttcc acgtgttgaa ggtacaactc cacacacaat tactggccgt
    34801 tacggttcag gaagcgtatt tatgaaaccg gctgcacctg gtacaggagt tatcgctggt
    34861 ggtcctgttc gtgccgtact tgaattagca ggtatcactg atatcttaag taaatcatta
    34921 ggatcaaaca caccaatcaa catggttcgt gctacaatcg atggtttaca aaaccttaaa
    34981 aatgctgaag atgttgcgaa attacgtggc aaaacagtag aagaattata caattaagga
    35041 gggaaaacta gttatggcta aattacaaat taccctcact cgtagtgtta ttggtcgtcc
    35101 tgaaacacaa cgtaaaactg ttgaagcttt aggtcttaaa aagactaaca gttcagtagt
    35161 tgttgaagat aaccctgcta ttcgtgggca aatcaacaaa gttaagcact tagtaacagt
    35221 agaagaaaaa taatcaagga ggtgccgaaa tgaaattaca tgagttaaaa ccggcagaag
    35281 gttcacgtaa agaacgcaat cgtgttggac gtggtgttgc gacaggtaac ggtaaaacaa
    35341 gtggtcgcgg acacaaaggt caaaaagctc gttcaggcgg tggtgtaaga ccaggatttg
    35401 aaggtggtca attaccatta ttccgtcgtt taccaaaacg tggttttact aacataaatc
    35461 gtaaagaata tgctattgtt aacttagacc aacttaataa atttgaagat ggtactgaag
    35521 taactccagc tttattagta gaatctggtg ttgttaagaa tgaaaaatct ggtatcaaaa
    35581 tactaggtaa tggttcactt gataagaaat tgacagtgaa agctcataaa ttctcagctt
    35641 cagcagcaga agctattgat gctaaaggtg gagcacacga ggtgatctaa tgattcaaac
    35701 ccttgtgaac ttctttagaa caaaagaggt tcgtaacaag attttcttca cactagcaat
    35761 gttagtaatt tttaaaatag ggacttatat accagctcca ggagtaaatc ctgcagcttt
    35821 tgataatccc caaggttctc aaggtgccac tgagttatta aatacttttg gtggcggagc
    35881 cttgaaacga ttttctattt ttgcaatggg tattgtaccc tacatcactg catcaatcgt
    35941 aatgcaatta ttacaaatgg atattgtccc taaattctca gaatgggcaa aacaaggtga
    36001 agtaggtaga agaaagttaa ataacgttac tcgttattta gcaatttctt tagcatttat
    36061 ccaatctata ggtatggcat tccaatttaa taattatctc aaaggtgcgc tgattatcaa
    36121 tcagtcaatt atgagttatt tattaatagc actagttttg acagcaggaa ctgctttctt
    36181 aatatggctt ggtgatcaaa tcactcagtt cggtgttggt aatggtattt ctattatcat
    36241 atttgcgggt attttatcaa cgttgccagc cagtctaatt caatttggac aaactgcgtt
    36301 cgttgggcaa gaagatacat cattagcatg gttgaaagta ttaggacttt tagtgtcact
    36361 gatactatta actgtaggtg ctatttatgt acttgaagcc gttcgtaaaa ttccgattca
    36421 atatgctaag aaacaaactg ctcaaagatt aggttcacag gcaacttatc tacctttaaa
    36481 agtgaactca gccggtgtta ttcctgtaat ctttgcaatg gcgttcttct tactgcctag
    36541 aacattaacg ttgttctatc cagataaaga atgggcacaa aacattgcga atgctgcaaa
    36601 tccttcaagt aatgttggta tggttgtata tattgtacta attatactat tcacatactt
    36661 ctatgcattt gtacaagtta atccggaaaa aatggctgat aaccttaaga aacaaggtag
    36721 ctatgttcca ggcattagac ctggtgaaca aaccaaaaaa tatattacta aagttttata
    36781 tcgtttaact tttgtaggtt ctatcttctt agccgttatt tcaattctac cgatattagc
    36841 aactaagttt atgggattac cacaatcaat tcagattggt ggtacaagtt tacttatcgt
    36901 tattggtgta gcgattgaaa caatgaaatc tttagaagct caagtatctc aaaaagaata
    36961 taaaggcttt ggtggtagat aattttagga gggcacttat gaatatcatt ttgatgggtt
    37021 tacctggcgc aggtaaagga actcaagcaa gtgaaattgt caagaaattc ccaatacccc
    37081 acatttcaac tggtgacatg ttcagaaaag ctataaaaga agaaactgaa ttaggtaaag
    37141 aagctaagtc ttatatggac cgtggcgaat tagttcctga tgaagtgact gtaggtatcg
    37201 ttaaggaaag aatttctgaa gacgatgcaa aaaaaggctt tttattagat ggcttcccaa
    37261 gaacaatcga gcaagctgag gcattaaata atattatgtc tgagcttgac agaaacattg
    37321 atgctgtcat caatatcgaa gttccggaag aagaattaat gaaccgtctt acaggtcgtc
    37381 gaatctgtga gtcatgtggt acaacgtatc atcttgtatt taatcctccg aaggtcgaag
    37441 gtatttgtga tatcgatggt ggtaaattgt atcaacgaga agatgataat cctgaaacgg
    37501 tagctaatcg tttgagtgtt aatattaaac aatctaagcc tattttagat ttctatgatc
    37561 aaaaaggtgt attgaaaaat attgatggtt caaaagatat tagcgacgtt accaaagatg
    37621 tcattgatat tttagatcat ttgtaataga tcaactttta gcggtctatt ttaagtgagg
    37681 catgatttaa tcatattaga tagatgagag tggcaattaa cgataattaa ttcccgtaat
    37741 ttttgtttaa cttataaaat taatcactga tagattcgta acaataaagt tgtctattga
    37801 cgattacctt actattgcaa aaagggggaa gttaatcaat ggctaaacaa gatgtaattg
    37861 aattagaagg tactgtatta gatactttac cgaacgcaat gtttaaagta gaattagaaa
    37921 atggtcatga gattttagct cacgtaagtg gtaaaatcag aatgaattac attcgtattc
    37981 tacctggcga caaagtaact gttgagatgt ctccgtacga tttaacacgc ggaagaatta
    38041 cttatcgtta taaataatcg tcactccata atatagggag gtataaaaat gaaagtaaga
    38101 ccatcagtaa aacctatttg cgaaaaatgt aaagtcatta aacgtaaagg taaagtaatg
    38161 gtaatttgtg aaaatccaaa acacaaacaa agacaaggtt aataaaagag aggtgtaaat
    38221 taatatggca cgtattgcag gagtagatat tccacgtgaa aaacgcgtag ttatctcatt
    38281 aacttatata tacggtatcg gtacgtcaac tgctcaaaaa attcttgaag aagctaacgt
    38341 atcagctgat actcgtgtga aagatttaac tgatgacgaa ttaggtcgca tccgtgaagt
    38401 tgtagacggt tataaagtcg aaggtgactt acgtcgtgaa actaacttaa atatcaaacg
    38461 tttaatggaa atttcatcat accgtggtat ccgtcaccgt cgtggtttac cagttcgtgg
    38521 tcaaaaaacg aaaaacaacg cgcgtactcg taaaggacca gttaaaacgg tagctaacaa
    38581 gaaaaaataa taggtaaagg aggcaaattt taaatggcac gtaaacaagt atctcgtaaa
    38641 cgtagagtga aaaagaatat tgaaaatggt gtagcacaca tccgttcaac attcaacaac
    38701 actattgtaa ctatcactga tgagttcggt aatgctttat catggtcatc agctggtgca
    38761 ttaggattca aaggatctaa aaaatcaaca ccatttgcag cacaaatggc ttctgaaact
    38821 gcatctaaat cagctatgga gcatggttta aaaacagttg aagtaacagt taaaggacct
    38881 ggtccaggtc gcgaatcagc tattcgtgca ttacaatctg caggtttaga agtaactgcg
    38941 atcagagacg ttactccagt acctcataac ggttgtcgtc caccaaaacg tcgtcgtgta
    39001 taatttatga tggtattgtt acaggtcact gagcaaacat tttaaattaa gtcgacgtat
    39061 ataaggagga tatttaaatg atagaaatcg aaaaacctag aattgagaca attgaaatta
    39121 gtgaagatgc taaattcggt aagttcgttg ttgaaccact agaacgtggc tacggtacta
    39181 cactaggaaa ctccttacgt cgtatcctac tatcttcatt accaggtgca gccgttaagt
    39241 atattgaaat tgagggagtt ttacatgaat tctcagcagt agacaatgta gttgaagatg
    39301 tttctacaat tattatgaac attaaacaat tagcattgaa aatttactct gaagaagata
    39361 aaactttaga aattgatgta cgtgatgaag gcgaagtaac agcaagcgac attacacatg
    39421 acagtgatgt tgaaatttta aacccagagc ttaaaattgc aacagtatct aaaggtggtc
    39481 acttaaaaat tcgtctagtt gctaacaagg gtagaggtta cgcattagca gaacaaaata
    39541 atactagtga tttaccaatt ggtgtaatcc ctgttgattc attgtattca cctgttgaac
    39601 gtgtgaacta tactgttgaa aatacacgtg taggtcaaag cagtgatttt gataaattaa
    39661 cattggatgt ttggactaat ggttcaatca caccacaaga atcagtttca ttagcagcaa
    39721 aaataatgac tgaacacttg aatatcttcg ttggtcttac tgatgaagcg caaaacgctg
    39781 aaatcatgat tgaaaaagaa gaagatcaaa aagaaaaagt attagaaatg tctattgaag
    39841 aattagactt atctgtacgt tcatataact gcttaaaacg cgcaggaatc aattctgttc
    39901 aagagttagc tgacaaatct gaagctgaca tgatgaaagt gcgtaattta ggtcgtaaat
    39961 ctttagaaga agttaaatac aaattagaag atttaggatt aggattaaga aaagaagatt
    40021 gataaaggag gttaactcat gggttacaga aaattaggtc gtacttctga tcaacgtaaa
    40081 gctatgttac gtgacttagc tacatcactt attattagtg aacgtattga aactacagaa
    40141 gctcgtgcaa aagaagttcg cagtgttgtt gagaaattaa tcactttagg taaaaaagga
    40201 gatttagctt ctcgtcgtaa tgcagctaaa actttacgta atgttgaaat cttaaacgaa
    40261 gatgaaacta cacaaactgc acttcaaaaa ttatttggtg aaatcgcaga gcgttacaca
    40321 gaacgtcaag gtggttacac tcgtatcctt aaacaaggcc ctcgtcgcgg tgacggtgct
    40381 gaatcagtaa ttatcgaatt agtataagaa tttatataaa tacactaact acttttatat
    40441 aaagcaaatg agtgcaacga taatgtttgc cacatacaaa tattgtctag ctcagagtac
    40501 cccatcaact aaataaagat ttaaagcgtg aactcaacaa acttatgatg gggtgcgcgc
    40561 ttttttattg tataagctat cggacttttg aacagaaatg tttacaagtc cgatttcttt
    40621 atatctactt ttttgagtgt gaatctaaaa atatgatcaa gctagtttga tcaatttctc
    40681 tagaactgaa tgaagtgaaa gtactatcgt tgaatcaaac gcggccaacc ctatgttagt
    40741 aaatcattta ttttattaac gtttattcat aattgttaga gaggaataaa tgtccttatc
    40801 attagttgtt aaacaaccct ttaatgatta gaaatgagtc agaaaatact agtaatatat
    40861 agcaaaccca gtcaatgtca tatacagcga tttataaata ttgtaaaata tgatagatac
    40921 acgaatcgta aaggagagag acaagtggag gataagaatt cagttattgt atttaaaaat
    40981 gtttcatttc aatatcaaag tgatgcatcc ttcacattga aagatgtttc ttttaatata
    41041 cctaaaggtc agtggacatc tattgttggt cataacggtt ctggaaaatc tacaattgcc
    41101 aagttaatga ttggcataga gaaagttaaa tctggagaaa ttttttataa taatcaagct
    41161 ataacagatg ataattttga aaagttaaga aaagacatag gaattgtatt tcagaatccg
    41221 gataatcaat ttgttggttc aattgtaaaa tacgatgtgg catttggact cgaaaatcat
    41281 gcggttccac atgacgaaat gcatagaaga gtcagcgaag cacttaaaca agttgatatg
    41341 ttagaacgtg cagattatga acctaatgca ttatctgggg gccagaagca gcgtgtggct
    41401 atagcaagtg tattagcact taacccctct gtcattatat tagatgaggc gacttctatg
    41461 ttagatcctg atgcacgtca aaatttattg gatttagtga gaaaagttaa atcagaacat
    41521 aatattacaa tcatttctat tacgcatgat ttatctgagg cgatggaagc agatcatgtt
    41581 atcgttatga ataaagggac tgtatataaa gaaggtacag cgattgaaat tttcgaccat
    41641 gcagaagagt taacaacaat aggtttagat ttgccattcc caatcaaaat aaatcaaatg
    41701 ctgggatacc aaacatcatt cttaacttat gaagggctgg tggatcaact atgactatac
    41761 gctttgacaa tgtaagttat acctatcaaa aagggacacc ataccagcat caagctattc
    41821 atgatgttaa tacagaattt gaacaaggta aatattacgc catcgttgga caaacgggta
    41881 gtggtaaatc aacattgata caaaatatta atgcactgtt aaagccaact actgggacag
    41941 ttacagttga tgacattact attacacata agaccaaaga taaatatatt agacctgtaa
    42001 gaaaaagaat tggaatggta tttcaatttc ccgaatctca attatttgag gacacagtag
    42061 agcgtgaaat gatatttgga cctaaaaact ttaaaatgaa tttagatgaa gccaaaaact
    42121 atgcccatcg tctgttgatg gatttaggtt tttcaagaga tgtaatgtca caatcaccat
    42181 ttcaaatgtc aggtggacaa atgcgtaaaa tagcgattgt atcgatattg gcaatgaatc
    42241 ctgatattat cgtggttgat gaacccacag caggacttga tccacaaagt aaacgacaag
    42301 taatgcgatt actaaagtca ctacaaacag atgaaaataa ggcaattatc ctaatttcac
    42361 atgatatgaa tgaagtcgcg cgttatgcag atgaagtcat cgttatgaaa gaaggtagta
    42421 tagtgtcgca aacatcacca aaagagctct tcaaagataa agaaaaattg gcggattggc
    42481 atattggttt gccagaaatt gttcagttac aatatgactt tgaacaaaaa catcaaacaa
    42541 aattaaaaga tattgcctta actgaagaag catttgtaag cttgtataag gagtggcaac
    42601 atgaaaaata aattgattat agggcgatat ttaccaatta attcttttgt tcatcatctt
    42661 gatccaagag caaagttaat gtttgttttt ctttttatta tattaatatt tttctgtcat
    42721 tcaccattaa catatctttg ggtgtttgca cttatattat tctttatgag attagcaaaa
    42781 attcaattat ggttcctaat caaaggttta acgccaatat ttttcttttt aatcttcaca
    42841 ttaatgatgc atatattttt aactaaaggt ggatatgtat tagttgaatg gcatggcatc
    42901 acgattgaaa ctaatggtat tttagaaggg ctatatatat cactgcgttt aattggtatt
    42961 gtgatgattg caacaattat gacactatct acaagtccaa ttgatttaac agatgcgttt
    43021 gaaagattac ttgcaccact aaagatgttt aaattaccag ttcatcaatt aagtatgata
    43081 atgtccattg cgttacgatt catcccgacg ttaatggatg agttagataa aatcattttg
    43141 gcgcaaaagt cgcgtggctc tgaaataagt tcagggaaca ttgcaacacg tattaaatca
    43201 tttattccat tactagtgcc actattcatc tcagctttcc aacgtgcaga agaattagcg
    43261 gttgcaatgg aagttagggg ttatgatgcc aatgttcaaa gaacgagcta cagacagctt
    43321 aaatggcaat tgagagatac attatcttta atcatgatta tcccatttgc aattatttta
    43381 ttcgtattaa aatattcagg agtgtaaatt catgcgtata ttagtagaaa ttgcgtatca
    43441 aggaaataat tttctaggtt ttcaaattca acaaaatggt cgaacggtac agcaacaatt
    43501 tgaaaagcta ttacaacgca tgcataaaag acatgtgaga atccatcctt caagtaggac
    43561 tgatagaggt gtacatgcga tacagcaata ctttcatttc gacacagagc tgaatatacc
    43621 tatgtcacaa tggcaatatg caatgaaccg aacgttacct gatgatattt atgtcaacaa
    43681 tgtagttaca gtcgatgacg attttcattg tcgttacgat tgtgttggta aacgctatcg
    43741 atataaagta tatcaagcac aacaccgcga tccatttcaa agtggtttga aaacattcat
    43801 tcctgaaacg ttggatttag ataaaatgaa cagagcggca caacaattca taggtacaca
    43861 tgattttacg ggtttttgtt cgcaaaaaac tgaagtagaa agcaaagtta gaacattata
    43921 ccaaagtgaa attgtgaaaa ccgatgatgg ctttgattat attgtcactg gatctggatt
    43981 tttatataac atggtgcgtg tcttagttgc atttttaata gaagtcggaa aagggcgtca
    44041 cgaagtatct gatgtaccaa aacttcttga atcaaagaat cgtaagaatg taccttttac
    44101 tgcaccggct gaaggattat atttagagaa aatttattta gatgaaaatg agttattaaa
    44161 agactttggt aacgatatca aaatacatcg taaaaaatca ttacaaaatg actgattgcc
    44221 attgacaaaa agcttgtgaa attataagat tattaacggt attgttttat atccacccca
    44281 cgataagccc cggaaactta ttgtgttaca agatatataa gcagaaacga acaacagtta
    44341 acaaaataaa tgaaattaaa cgttttaaaa atgaaacaaa tgaaatcatc tattaggtta
    44401 tgaaactgtt tatagcttga atagaagcat ttatttttta ggaggacaat tattatgcgt
    44461 caaacattta tggcaaatga atcaaacatt gagcgcaaat ggtatgttat cgatgctgaa
    44521 ggccaaacat taggtcgttt atcatcagaa gtagcatcta tcttacgcgg taaaaataaa
    44581 gcaacttaca caccacacgt tgatactggt gattatgtaa tcgttattaa tgcatcaaaa
    44641 atcgaattta ctggtaacaa agaaactgac aaagtttact accgtcactc aaatcaccca
    44701 ggtggtatca aatcaatcac tgctggtgaa ttaagaagaa ctaatccaga acgtttaatt
    44761 gaaaactcaa ttaaaggtat gttaccaagc actcgtttag gcgaaaaaca aggtaaaaaa
    44821 ttatttgtat atggtggcgc tgaacatcca cacgctgcac aacaaccaga aaactacgaa
    44881 ttacgtggtt aattagaagg aggaaatgac tttggcacaa gttgaatata gaggcacagg
    44941 ccgtcgtaaa aactcagtag cacgtgtacg tttagtacca ggtgaaggta acatcacagt
    45001 taataaccgt gacgtacgcg aatacttacc attcgaatca ttaattttag acttaaacca
    45061 accatttgat gtaactgaaa ctaaaggtaa ctatgatgtt ttagttaacg ttcatggtgg
    45121 tggtttcact ggacaagctc aagctatccg tcacggaatc gctcgtgcat tattagaagc
    45181 agatcctgaa tacagaggtt ctttaaaacg cgctggatta cttactcgtg acccacgtat
    45241 gaaagaacgt aaaaaaccag gtcttaaagc agctcgtcgt tcacctcaat tctcaaaacg
    45301 ttaagctgca actgttgcga acttgttcgt ttacagatgg agttcgcaaa ttgcgtcagc
    45361 aatttgtgtt caactgaaga aacgtttaca acactctttg gattattcca aagagtgttt
    45421 tttgtatttt tatagagtca tttagacacc atttagttac ccctagggaa ctaatttgtt
    45481 tcaattctgc ttaaaattca atgatatgaa actttaggaa accatatgaa atgaccttgt
    45541 ttttctttgg gattcgtacg acaagtagat agaggttgta atgatattcg atagatatcg
    45601 tattgaatgt ttgcaaactg aggttgaagg acagctttcg agtaaaaagg aaaattttcg
    45661 agtaactcaa aagaaaaata taaaaaaatc atgagaaacc aatgatatca agcgttttgt
    45721 gagctttcga gtaaagagga taattttcga gtaactcaaa agaaaatact aaaaaatcat
    45781 gggaaatcat tgatatcaag ggttttgtga gctttcgagt aaagaggcgg attttcgagt
    45841 agtattattt aataagaatt acaggttaaa taaaatacct actaatcaga aggtgacaga
    45901 gattgtagaa tttctatcag atggaaagtt agcaagtagg ctagaaattc aagaaacaat
    45961 gggacttcaa aaaagttata catctgagtt aattgctgaa ctgaagaagt tagagattat
    46021 cggatctgaa ggtagaggtc cgggaactag atattattta attagagact aataaattca
    46081 tcaagtgata accggacgat aacctattga tatacataaa aacattgata aatcaatata
    46141 tttacgaccg gacgataacc ggacgatacg agagtatata ccaccggaca gcagtttatt
    46201 tagttaccct ttagttaccc cggagtgata tttggtgcaa tactatgcaa tcgaaaaaat
    46261 cagaaatcct ataatatcat gccttaagac aatatatgca actatacgaa accctaaagt
    46321 aaatcaggtc ttaaagcagc tcgtcgttca cctcaattct caaaacgtta attgtcggac
    46381 gatatataca caaaacacct cgatgttatg tcgaggtgtt tttttgcgtt tgtgtgggga
    46441 atatgaaaag tatgtagtat aaatgaacgt tcctttattt aatgtctcag gaatagaata
    46501 aattcaacta tgaattattg atttacacgt ataatttgta catgcttaca caatcaaaag
    46561 tgtacattat taaattgtca tttagcttgc ggaggacgga cgataaccgg tcgataatgt
    46621 tctaatcata gtggttcaag ggaaagggct atcggatgaa aaccggacga taactcaaga
    46681 accatgattt aagagtgtta tcaaaataag gagtgactta attgaaagat tctatatttt
    46741 ggaagaaagc ttttattcct gtttatttta ttgttgcgat gctggtgttt ctacttttta
    46801 ggttttatat taaaacagac aacttttcta tgtatttaat gattatcttc ttaatttgtt
    46861 taggaactgc atctatcatt tataactata aaaacaatcg ataaatataa gtatgaaatg
    46921 aataagtcac aattagatct aagtcttgct gtggcttttt ttatcgaaat gacaatttca
    46981 tgttgctata aaacagcatt ttcaaaccgt cataaaacaa cattttcagc ccgtcataaa
    47041 acaacatttt cagcccgcca taaaacgaca atttcaaacc gccattgact aaacacctca
    47101 ttcccaaata tgctaacaat cctccacatc aatcaatccg acattcttca ttatcacact
    47161 gcacaaaatc tactcatgca tttttggaat acttagtatt acaaataacg atttttattc
    47221 atcttacaaa ggatatataa tgtactgaag gcaattttta tgtattacaa atctaatcgt
    47281 acatgtaaaa ttttgaaaaa catcattaat tttgcgtaac tatcattaga ttacaaatca
    47341 caatgcaatt acatgtaata cacatctaca catcacattt gaagggaaat gaatataaat
    47401 gactggtaaa aagtacactg cagccgatat ggttattgat actttaaaaa ataatggggt
    47461 agaatatgtt tttggtattc cgggtgcaaa gatagactat ctatttaatg ctttaattga
    47521 tgatggtcct gaacttattg tcacgcgtca tgaacaaaat gccgcaatga tggcgcaagg
    47581 tattggaaga ttaacaggca aacctggtgt agtacttgtt acaagtggcc ctggtgtaag
    47641 taatttaacg actggactat taacagctac atctgaaggg gatcctgtat tagcgttagg
    47701 tggccaagtg aaacgtaatg atttattacg attaacgcat caaagtattg ataatgctgc
    47761 gctattaaaa tattcatcaa aatacagtga agaagtacaa gatcctgaat cattatcaga
    47821 agttatgaca aatgcaattc gaattgctac ttcaggaaaa aatggcgcaa gttttattag
    47881 tattccgcaa gacgttattt cttcaccagc tgaatctaaa gcgatatcac tttgccaaaa
    47941 accaaattta ggagtaccga gtgaacaaga tattaatgat gtcattgaag cgattaaaaa
    48001 tgcatcattt cctgttttat tagctggtat gagaagttca agtgcagacg aaacaaatgc
    48061 cattcgcaaa ttagttgagc gcacgaattt accagttgta gaaacattcc aaggtgcagg
    48121 tttaattagt cgtgaattag aaaatcattt ctttgggcga gtgggtttat tccgtaatca
    48181 agttggtgat gaattattac gtaaaagtga tttagttgtt acaatcggtt atgatcctat
    48241 agaatatgag gctagtaact ggaataaaga attagatacg caaataatca atattgacga
    48301 agttcaagct gaaattacta attatatgca accgaaaaaa gagttgattg gtaatattgc
    48361 taaaacgatt gaaatgattt ctgacaaagt agatgaacca tttataaatc aacaacattt
    48421 agatgaatta gaacagttaa gagcgcatat tgatcaagaa actggtatta aagcgacaca
    48481 tgaagaaggc atcttacacc cagttgaaat tatagaatct atgcaaaagg tattaactga
    48541 tgaaacaaca gtgacagttg atgttggtag tcactatatt tggatggcac gtaatttcag
    48601 aagttacaat ccaagacatt tattatttag taacggtatg caaacacttg gtgtagcatt
    48661 accgtgggca atttcagctg cacttgtacg ccctaatacg caagttgtat ccgttgctgg
    48721 cgatggaggc tttttatttt catcacaaga tttagaaacg gccgtacgta aaaatctaaa
    48781 cattattcaa cttatttgga acgatggaaa atataacatg gttgaattcc aagaagaaat
    48841 gaaatataaa cgttcatcag gtgtcgactt cggtcctgta gatttcgtaa aatatgctga
    48901 atcatttggc gcaaaaggtt tacgagttac taatcaagaa gaattagaag cggcaattaa
    48961 agaggggtat gaaacagatg gcccagtatt aattgatata cctgtaaatt acaaagataa
    49021 tatcaaactt tcaacaaata tgttacctga cgtatttaac taaaatacag ataaatgtta
    49081 atgaggagtg ggaaatttta tggctagtgt tttatatcaa catggtacat taggcacatt
    49141 aatggcaggt ttattaaaag gaactgcatc aataaatgaa ttattgcagc atggtgattt
    49201 aggtatcgct acactaacag gttcaaatgg tgaggtcatc tttttagatg gaaaagccta
    49261 tcatgcaaat gaacacaaag aatttgtgga attaaaaggt gatgagttaa caccatatgc
    49321 aactgtaact aaattcgtag cagatacaag ctatgaaacg aaagataaat cttctgaagc
    49381 agtttttgca gaaattaagg aaaagatgtt gagtgaaaat ttattttctg cagtaaaaat
    49441 ttcaggctta tttaaaaaaa tgcatgtacg tatgatgccg gctcaagagc caccatatac
    49501 acgtttaatt gattcagcta gaagacaacc tgaacaaact gaaacgtacg tcaaaggttc
    49561 agttgttggt ttctttacac cagaattatt ccatggtatt ggatcagcag gtttccatgt
    49621 acactttgcc aatgatgatc gtaactttgg tgggcatgtc ttagactttg aagtagaaga
    49681 tgttaaagta gaaatccaaa atattgaaac atttgaacag cattttccaa ttcatgatga
    49741 agatttcact aatgcaaata ttgactataa agatatttca gatgaaatta gagaagctga
    49801 ataacattaa ctgtataatg aatgcgtaaa tgtattatca gtttatgaaa attgacttca
    49861 taatgcgcga tttagaaatg gtagtttgtt aatatgatta atcatgacta caatagaaca
    49921 aatatattta tgattacgtc tatgtaataa aataaatccc ttcactatta gctgtagtga
    49981 ggggatttat ttaggtttca gatatttgag atttgctgtt atgtttagat tataaattga
    50041 ggaagacaat aatatagaat ttactttagt ataggccaat ctattgtctg gagaagcaaa
    50101 caacaataat ttgcaagttc aataactaaa aagacaaacg ccaatttttc agcgcttgcc
    50161 ctataaaact attttcaaat tattatttaa ctacaatttg tatttgtttg attgtacttg
    50221 gatcaattga atttttagca tcgtcatttt tctttagatt cactactttt ttattaccat
    50281 cattcaaagt aagtgtataa gttgctgttt gtgcattatt aattttttct gttgtaacac
    50341 cacgttgaga agctaattca ttttttactt tactgtcaat ttcttgataa agtacctttt
    50401 tattttctgg aaaaacaaag taagttcgat gtaatgcagt aataccatct actgaaatcg
    50461 tgtaaggaac agtgtgataa ccatccattg tcatttcttt atagccgtta ttactatctg
    50521 cagatgcttc gtgactaggt aatgcagctc cgaccgttga taataatccc aatgctaaag
    50581 tggcagtaac aaatgatttt agtttcatat ctcaatctcc ttttaaaatt gtggtatatt
    50641 acactattta tataacatgt ttcataaagt ttaaaacata ctttttgatt tttttatatt
    50701 tttgattttt agtaatagtt tttaacgagg gatatgaccc gtgtattttg aaaagtggta
    50761 agcaatgttt ttagtttata gggattcatt agttgtatat aataagcatg aaaagcatat
    50821 agtcgatctt atacttttaa ttgagactta tagtgtattt aagttataga taaattcatt
    50881 aaaatattat ggaggaatga gtatgtcaaa gcgtctatta ttgtttgatt ttgatgaaac
    50941 atattttaaa cataatacaa atgaagaaga tttaagtcat ttaagagaaa tggaaaaatt
    51001 gttggaaaaa ctaactaata ataatgaagt gatcactgct gtattgacag gaagtacatt
    51061 tcaaagtgtc atggataaaa tggatcaagt taatatgacg tttaaaccat tacatatctt
    51121 ttctgatttg agttctaaaa tgttcacttg gaataatggc gaatatgttg aatcagaaac
    51181 atataaaaag aaagtcttga gcgaaccatt tttatttgaa gatattgagg atatattacg
    51241 tcatatttct gcgcaatata atgtcgaatt tattccacaa agagcatttg aaggtaatga
    51301 aacacattat aatttttatt ttcattcaac aggtaatcac aacaatgata ggcgtattct
    51361 agaagcactt gtcagatacg caaatgacca aaactataca gcgagattta gtcgaagcaa
    51421 tccattagct ggtgatcctg aaaatgcgta tgatattgac tttacaccgt caaatgctgg
    51481 aaaattatat gctactcaat ttctgatgaa gaaatataat atacccgtaa aatcaatatt
    51541 aggttttgga gatagcggca atgacgaagc atatttaagc tatcttgaac atgcctattt
    51601 gatgtcgaat agtagagatg aagcattaaa gcagaaattt agattaacaa aatatccata
    51661 ttatcaaggg ataacactgc atgttaaaga atttgttgaa ggtaagtatg attattgatt
    51721 ggttgagtga tatgtatact ttttaagtgc aaatattaat atttaaaatt tgaggaatga
    51781 ttagataata tggtgaatcg actacacttt agttttaaaa aatttatttg taagttgatt
    51841 tgtctaacta agtgtagacg attcatagtt taatcaatat atttgaatac tttgtaaatt
    51901 aaataaacat ttaatattga tactattgaa gatatagagg gctttgatct ctattggctt
    51961 ttttcatcga ttaattcaat ccattttttg gatactgctt cgtaagaaaa gtttgtcttt
    52021 attgttgttc tagcattttc agaaaactga gatatcaatg tttctttttt taatacatga
    52081 attatttttt ttgccaattc attaatatta tccttctttt ttgttattat tccatttata
    52141 ttattttgga ttatagattt aggaccataa ttaataggat atgaaataac tggaacaccg
    52201 taactcatgg cctctagtaa actcattggg agaccttcat aatctgatgt cagtacactt
    52261 agagaggttt ttgtataaag agcacgtatg tcaaatgcgt aatcatggat gaacacatta
    52321 tcttgcaatt taagtttttt aataagtttt gtgtaatttt ctttttgcgt accggtaccg
    52381 tatatgtgta acttaacatc ctttactttt tttcttacaa tatttatagc ggaaatgata
    52441 tgtgtgatat ttttcatagc tacaaatctt tgtaatacaa taatagaatt tttttctcga
    52501 atattttgtg ttaaattttc ttcaaaagat atagcattag gaataacctt tatattattg
    52561 taatcaccaa attgttttat aatgtcatct ttttgttctt tagttaatac aactaaagta
    52621 tctaactctt taaggtttag taacatgttt ctgaactctg gtttaatctc agcgccatag
    52681 gagtaagggg acatgaaatg attcgtatgt atagtaaata tttttttgat atcattattc
    52741 tgcatgttct ctactttatg ataagtacct ataccgtcta gtattaatac gtcgtttgaa
    52801 gttaagtttt tatccaacca atatgaatgg aacgctttat tatttttaaa gtttaatact
    52861 tctttgctgt ttttatcaaa ataaaatata ttgactatat tttcgttatc cccataccaa
    52921 tatgataagt aacaaaagcc gtcatttgat aaatatttaa cttcactcat tttattttta
    52981 tcgttgaaag ttatttcttt tcgaagtatt ttattttgaa aaacatgtct tttaaagcgt
    53041 tttcgatttt gaaaataatc aatgtgtgat aattgaccat ttatccattt tttatacatt
    53101 atgtaatggt tatctttaaa gtatctagca tatttttttc ttcatattcg tctttttgaa
    53161 tataaaagcc ttcttgattt aaaagattta atttttcaaa tgtttgcata tttttatttt
    53221 cgatttctgt attttcaaca tcatacagca tcttcaattc ttcgtataag ttaacaattt
    53281 ttacttgttt atgtaaccgt cctgaatttg ttagcttagc tcttaatgga tcatagtttt
    53341 tgtcatccaa agttaataag gcacatgaat agcctttttc agctaaaagt ttagatctat
    53401 ttaacataac tgatgttata ccacctgctt tttctggtat tgaatacatt aacatataag
    53461 tagtcataat ttcctcctat ttcttgcact tgataattaa ttctccgtaa ttatagtagt
    53521 aatcttcatc tacatatatt ttggagaacg tttctaaaga actgtaattt tctatttcag
    53581 caactataat atgatttaat gctaaataag gattagagcc attaaaaaca attttgggct
    53641 ttaatatttc ataatcctta aaaacctcag aaattttttc gttatttttt tgtacttcaa
    53701 tcttgtttaa ctttaatatt aattcattgt tgtaattata ctcatttaat gtcatgttga
    53761 taaatccctg ttttctccat cattaaaatt ttattcgatg cccatctatt tatctaagta
    53821 aatagataat atcattttat tatttatagc gttttaggtt atgtacaatt atattttctt
    53881 atttattagg ttggttgtca atgttgttgg aacttttcag ctgatatgct gtaaaagcta
    53941 ctaaagataa ataatgtaat gaagtattga caggatatta tgaggaacta gattctttct
    54001 atttaaaaat ttttagtttg aaatacttat tgatggtaaa ctgattatcg aacacagcga
    54061 attgacagtg actaagttgc aataaaaatt tcaaattgta ggactgaccg ttatgactaa
    54121 gagaaaaatg tgaatatact ttaaaataga agtaatacaa ctcgttgtat caagtataaa
    54181 tgttactgat gtcttaatgc gtctttgaat tcctattcaa aaaatatcaa agtggttaac
    54241 taaatgttat aaaaatagag gaaatgcttt tgcagataat tggaaaatga tgtgaatcta
    54301 tcaaaaagac ttaaagtttt agaagaacat ataataaaaa aaggttatgc acatctttaa
    54361 taaagaataa aaagcaattt tgatttcata gacaaaaact tccacaagat tcaggcaacg
    54421 tatatgtgtg aggtattttg tgtctttgaa agcggatagg atgatgtaaa aaaacgtgat
    54481 tattcattcc aacatattcg acgagaaatg taaaaaagca aattcataaa atttccaggg
    54541 gaagcaaaaa atataaggta gcgtaaaaat gacgcaggaa ctggagaaag aattgatacc
    54601 aaaataaaca taagaggtta agaatatatg aataaaacaa actttgggga ttatttaaat
    54661 aaaagtaaga gcaggaaaat atataagatt tttgatcaaa atttgaagcg agagtttagt
    54721 tattggcact ttaggaaact tttcaaatct tatacaaggc agtctgatgt acatgagtta
    54781 aaagtgtgta ctcaaaatga tggtactatg gagcaaatat ggatagataa agcaaatcaa
    54841 tttggagtgg cagtgacttg gaaagataat agtattattg gatttgttat gcgtccgtta
    54901 atcaattatg atgctattaa gaatgaaacg actttaaaat acgcagtgcc gacaacagat
    54961 tgctatgagg ttttttgggg tggagataat gaattatata attatcacta tttataccca
    55021 catcaaaggt atgctattga tttagttatt aaagaaaatc ataaaacata taagaacaaa
    55081 ggaaaagtaa atactgatta tttttatttt ggaaaagata tcattgcgcc agcaaatggt
    55141 acagttgaaa aagtagcgaa tggggttcaa gacaacagta ttggaagcac gaatgaatca
    55201 cagtttttag gaaattatat tgtaatcaag cacgcagaaa atgagtatag cctaatagct
    55261 catttacaac aatattcaat cattgtgaat gaggggcaaa atgttaaata tggtgacatc
    55321 attgggaagg ttgggaattc tggcaattct actgaacctc atatacattt tcaagtaatg
    55381 aatgataaga atattgaagc atgtacatct ttgaaaattc gatttataaa taatcgagaa
    55441 cttatcaagg gtgatgtggt ctgcggatta caaggtgaat gatggcgata tttataaaat
    55501 ctcgacacta taaaaatggt atagtgccga gattttcttg cttatttagt taattcaaag
    55561 cgtacgccgg attcatttgt agtcgatgta tctttgtttg taatagagta tccagtcatt
    55621 gaaattttag attcaatatc tgaagcggga tttgtagatt cgggattata gaagctacat
    55681 tcataagttt tatcattttt ctttttaaga ataaacattc ctttggcttt aacttcgact
    55741 ttagtaccat taatttcaaa agttttagcg ctatcactat aattgacacc agcccaaacc
    55801 gattcattat ctttcacaac gtggaagtca tcatcttgtt taacgacagt tacttggctt
    55861 gctttggatt taaaattatc ttttgttata cctggataca acacatatcc atatttattg
    55921 tctttatcag aatgcttttg agttacttca taatactcat cagttttgtc ttctgatttt
    55981 tgacttttat ttatatcact ccacttacca gtatgacttt ctttttttac agttattttc
    56041 gatttgttta aaaaatgata gcctatattg tttttaggtt tattggtgga ctctaaaaag
    56101 acggaattgg tatcctgatt atcggaagcg gttgtttgtt tatcgtctgt atataacgta
    56161 tacccattcg ttttgcgatt ttcaatcgtt gtaactggat tctttgatga atcagtactt
    56221 ttaatgccag ttcctaagaa gacaatttta tcgtttaata tgaaatatga ttttttggca
    56281 gttaaagttt tgtcctgatt ttcaaaatcc attccgatac tagcatgttg gtcatcgaat
    56341 tttgttccgc ctacaaaagt tttactcgac tttttaacat ccgtaccttt aggttcttca
    56401 ttttctatag ttgtagtacc tgctaaacgt ttcatatcgg cagtcgccca gaagttatca
    56461 cggtagtgtt tcacatcgct attgtataaa taagacattc cagcaccagt atgccaacct
    56521 tttaggtttt cattattgat actttcgtaa cgtgcgacgt ttttcgacgt catacttaaa
    56581 ccaaatgcaa agtctaagcc tttattgtga taggtgacac gatccatgtc attatatatt
    56641 ttaagttgtt gtgttaaatc gttagtagaa atagtgctgt cttccattaa agacttcatt
    56701 ttgcttatat ccgaataaga gcttaaataa tcgttttgtt tataacttga atcagattta
    56761 actgaagttt taacgatttg tttatattta gcttttgttg aatcatccat ggcatcactt
    56821 aatctcaaca atgatttcat tacagttgca gatactgagt gactcgtttc attttcacgg
    56881 ctaatggctc taccacgtga taaatccatc atttcacctt tataaatgag tggcataaat
    56941 ccttcatcaa tccacgactt taatgttgta tcattttgat tactatcttt aaaagatgtt
    57001 tcttttatca tcggcatcat ttgagaaata ccctctaaga gtacaacgcc ataagcacca
    57061 gtgtatggga cgtcttgatg atcaatataa gagccgtctt tatagaatcc attacgttct
    57121 ttaccagttg cattactttg aacgtaagtg aagactttat taaatgcatc tattgattct
    57181 ttcatcatag ttgtatcttc ttcgataata ctttctaaaa gttttacttt agcaatgtct
    57241 actaaatttc cccctttagc ttgttcaggt tgtcctactg atgataatat tttgtcactt
    57301 tctggggcga aagttttgat aggggcagtg tattttttct tttcatcact tgaaatatca
    57361 ccattcagta atattagtgt atttgttaat gctctaggtg ttccaatttc ataatcccac
    57421 caatttaagt tggtatttct agaagtttta tttttaaaat tctcagtcag ttcttttact
    57481 ttatcagtcg gttcttttcc atatgcattt ttatgcagcc actcaagggc atctttaact
    57541 ttgtttttat tatccggagt attcaactta gtatttttat gcttcatcgc ttctgcgatt
    57601 ttctcaatat tacgataggt acgagtcata tccgcagact tcgtatctaa atcttttgag
    57661 ttttcccaca agtatttcct atcactttca gttttcatgc tacttagtaa attcgtcgcc
    57721 tctttctccg tagcctcaaa cttctttttc attgcatcat tattctcatc atactgatta
    57781 taaccgtagt taacgttcag ccatgtgttc ctcaactttt cataatctgt cgtttgaaca
    57841 ttcgtatcag ccacagcgat ttgatgttta tcaacacttc tgaattcact atcattaaaa
    57901 gtaatcacac cagccattaa taacgtaatg gtagatattt tttgccattt cttcattcta
    57961 tatgtcattg acatgtctcc tttttgtgtt gcgcgtgcgc aatgaatatt atgattaaat
    58021 aatgattcaa tttttcaaaa ttcgttaacg tatacaaatg actgtttact gtcaaacaat
    58081 ccacaaagaa tgttgatgca tataaacaat cgatcaccca aattttccgc atcacccaaa
    58141 aattgcaacg aaaataattt ttaaaaaatt aaatattatc aatcttagtg attatatcat
    58201 tttaaatatt taagttatac aatttttaaa gtaattaaaa acgatgaaat gtaaaatgtt
    58261 aaaaaagaga caaatttaaa tttgagtaat aaaataagaa gtattcaaac gaagatggca
    58321 atatataaac caacataact ttagacgacc aaacataact gaaaggatag tcgcaatgaa
    58381 aactaaagaa gtcgtagcgc tcatgaatat atctcaagac actttaagat attatgaaaa
    58441 ggttggtgtg attccacctg ttaatcgaga tgaaaatgga tatagaatat ataatgatag
    58501 tgatttaaat tggatttatt tagtgaaaaa tttgcgaaat gcaggcgtca gtattgaatc
    58561 gcttatcgaa ttttgtaggt tagcgcagct tcctaaaaat gaaaatattc aagcacagca
    58621 aaagcaaatt ttaaataagc aactcgaaga attaaatgaa aacttaaaga caattcatga
    58681 tgcgagagac ttactacaat ataaaattga taattatgat aatcatattg ctaaaatcaa
    58741 tgctagtgat aatcatgatg ccaatgttga acgtctttgg gagagaaagt aaacctatgg
    58801 cttgctatag agtttgctcc atggtttata gtgagcttac aagaaaaagg aggttcattt
    58861 tatgaatcat attgaaataa gtaaagatgt aaagatacca gtattaggtt tcggagtatt
    58921 tcaaattcct caagaacaaa cagcagaagc ggttaaagaa gcaattaaag cgggttatag
    58981 acatattgat acagcgcaaa gttatttaaa tgaaactgaa gtaggtcaag gtattgaagc
    59041 ttcaggtatt gatagaagtg aactattcat tacgactaaa gtatggattg aaaatgttaa
    59101 ctatgaagat actatcaaat caatcgaacg atcattacaa cgattaaatt tagactatct
    59161 tgatctagtg cttattcacc aaccttataa tgatgtatat ggctcatggc gtgcattaga
    59221 agagttaaaa gaaaatggta aaattaaagc aatcggtgta tctaacttcg gcgttgatcg
    59281 aattgtagat ttaggtattc acaatcaaat tcaaccacaa gtgaaccaaa tagaaattaa
    59341 tccattccat caacaagaag aacaagttgc agcacttcaa caagaaaatg ttgtggtaga
    59401 agcttgggca ccatttgcag aaggtaaaaa tcaattattc caaaatcaat tgttgcaggc
    59461 cattgcagat aaatataaca aatcaattgc acaagttatt ttacgctggt tagtagaacg
    59521 tgacatcgtt gtactcgcaa aatcagtgaa tccagaacgt atggctcaaa acttagatat
    59581 atttgatttt gaacttacag aagaagataa acaacaaatt gcgacattag aagaaagtaa
    59641 tagccaattt ttctcacatg ctgatccaga gatgattaaa gcacttacaa gcagagaatt
    59701 agatgtttaa tcataatata acaaagtaaa taatttacat tacactaacc tgaaacttgg
    59761 atgttaaagt ctatgtttca ggttattttt tactcttaaa aagtgaaagg agcaagcaaa
    59821 taagttatta tatattttta tattatgcaa taacttacct aaggttataa ttagataatt
    59881 aatatgtctt ggaattaatt atctaataag ttgtatagca ggtggcgata tgacatatat
    59941 acccttttct attattacat taattacagg tatcattatg catatgacaa tgtactttgt
    60001 aaaatttgaa tgttggaaaa tgccattatt catgaagatt atttttacaa tctaaaagca
    60061 gtaaagactc ataatatagc caaaaacgtt aataaaagtt tgttaaatga taagggggtg
    60121 agtattggta aatttattca aaaggttaaa gggaaaaatc ctacctagag agatccaaaa
    60181 actaaatgga ctatttccaa aaataaaggg caaccacatg gtgattctta ttggaagtta
    60241 ataaataaca aaggaaacag aatagattct ttaactaaag aaggaaaaaa tcttaaggga
    60301 ataaggtgtt gtaaattatg tgctttgata taaataattt gaatataaaa aagttgaatt
    60361 ttagaaaggt aaaaaacgca attcatttaa gtttaagtgg cgataaatac cagtttttgg
    60421 aggacggtaa aactatcaat aatacttatt ttttagctgt atatgataat gcaataaaca
    60481 tttttgaaga tttgttttcg ccttctgatt ctataaattt gg
//
LOCUS       DAPSKH010000006        59639 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPSKH010000006 DAPSKH010000000
VERSION     DAPSKH010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 59639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59639
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.006"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..872)
                     /locus_tag="RPH49_000483"
     CDS             complement(<1..872)
                     /locus_tag="RPH49_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PP2C family protein-serine/threonine
                     phosphatase"
                     /protein_id="HDY5123674.1"
                     /translation="MEEFKQHYKGLIDESLTCQDKVELIKKCEKYTDEVIRKDVLPED
                     IVDIHKNYILTLNLTREDVFKTLDVLQEIVKGFGYSYRDYQRLVDKLQVHDKEIDLAS
                     SLQQTMLKTDIPQFDSIQIGVISVAAQKVSGDYFNLIDHNDGTMSFAVADVIGKGIPA
                     ALAMSMIKFGMDSYGHSQLPSDGLKRLNRVVEKNINQNMFVTMFYGLYEEMNHLLYCS
                     SAGHEPGYIYRAEKEEFEEISVRGRVLGISSQTRYQQQEIPIYLDDLIIILTDGVTEA
                     RNSEGTFIDKQKLL"
     gene            complement(1221..1583)
                     /locus_tag="RPH49_000484"
     CDS             complement(1221..1583)
                     /locus_tag="RPH49_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDY5123675.1"
                     /translation="MIRRGDVYLADLSPVQGSEQGGVRPVVIIQNDTGNKYSPTVIVA
                     AITGRINKAKIPTHVEIEKKKYKLDKDSVILLEQIRTLDKKRLKEKLTYLSDDKMKEV
                     DNALMISLGLNAVAHQKN"
     gene            complement(1580..1750)
                     /gene="mazE"
                     /locus_tag="RPH49_000485"
     CDS             complement(1580..1750)
                     /gene="mazE"
                     /locus_tag="RPH49_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HDY5123676.1"
                     /translation="MLSFSQNRSHSLEQSLKEGYSQMADLNLSLANEAFPIECEACDC
                     NESYLSSNSTNE"
     gene            complement(1835..2983)
                     /gene="alr"
                     /locus_tag="RPH49_000486"
     CDS             complement(1835..2983)
                     /gene="alr"
                     /locus_tag="RPH49_000486"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDY5123677.1"
                     /translation="MSDKYYRSAYMNVDLNAVASNFKVFSTLHPNKTVMAVVKANAYG
                     LGSVKVARHLMENGATFFAVATLDEAIELRMHGITAKILVLGVLPAKDIDKAIQHRVA
                     LTVPSKQWLKEAIKNISGEQEKKLWLHIKLDTGMGRLGIKDTKTYQEVIEIIQQYEQL
                     VFEGVFTHFACADEPGDMTTEQYQRFKDMVNEAIKPEYIHCQNSAGSLLMDCQFCNAI
                     RPGISLYGYYPSEYVQQKVKVHLKPSVQLIANVVQTKTLQAGESVSYGATYTATDPTT
                     IALLPIGYADGYLRIMQGSFVNVNGHQCEIIGRVCMDQTIVKVPNQVKAGDSVILIDN
                     HRESPQSVEVAAEKQHTINYEVLCNLSRRLPRIYHDGDQRFVTNELLK"
     gene            complement(3049..3408)
                     /locus_tag="RPH49_000487"
     CDS             complement(3049..3408)
                     /locus_tag="RPH49_000487"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDY5123678.1"
                     /translation="MIHGIGVDLIEIDRIKALYSKQPKLVERILTKNEQHKFNNFTHE
                     QRKIEFLAGRFATKEAFSKALGTGLGKHVAFNDIDCYNDELGKPKIDYEGFIVHVSIS
                     HTEHYAMSQVVLEKSAF"
     gene            complement(3412..3903)
                     /locus_tag="RPH49_000488"
     CDS             complement(3412..3903)
                     /locus_tag="RPH49_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDY5123679.1"
                     /translation="MRDYNFMSPHAKKVMRLSAVMFWIPIALVLLIAFNILNWLFWEI
                     LDNYISIVSSVIIILLVAVFTLVIAPVYRYKHCRYAFEKHHLRVRNGILFLDEKVIPY
                     FRIQNIDIDVGPIMRRYRLATLTLFTAGGQAEIELIDRSEARRLKRWLNNERHLENNK
                     NEE"
     gene            complement(3890..5473)
                     /locus_tag="RPH49_000489"
     CDS             complement(3890..5473)
                     /locus_tag="RPH49_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDY5123680.1"
                     /translation="MSEPQKLHPISYFNGIINAIKQNIVVFFIFIIFQLKDFDYTNPE
                     SYLWIGIVFVFFLISYISQIVGIMNTRYWIEDNYFILTTGIFNKKRKELNIKRIQSVD
                     MTQGVVNQIIGGVDLQIKTPSDGIVLSVISKKQGEYLERYIDQLQTELKTEGAQKSSA
                     EKNDNCNHDIEGNVEDIAEGRLDEVQNTDSMLNQKNKRIPIYQMNFKESLFMAMTSGA
                     IGVTLAALVPIYGAVRELIPWSKLNHEISQWVQIVSISVLIIILLVLIVAYIIGTIIT
                     MIRFYGFSVMLENEQLKIEYGLFNKKKVTVPTRRLQAVVERQSYIRRIFGYTAIHFII
                     TSDFENKKIEDDDNDSGSVTILPFIKRDKAYQIIQNLVPDLSYQQVNEGMPFSGFHRH
                     FLMPSIIVIAMAGIGCYFWNQLLLLFTIITIVIIGLFVIKGYLYVKHAGFKMTEEQIT
                     IQNFELLKRNIYYFKAHHIIGFDTWQHTLLKRNNLNNFSFIVAKGVGAQSINLKYARS
                     EDANKLKSWYLRGENDEGL"
     gene            complement(5466..5945)
                     /locus_tag="RPH49_000490"
     CDS             complement(5466..5945)
                     /locus_tag="RPH49_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123681.1"
                     /translation="MSDYTKLSKSPKSALLYYYITNGLEFILSVAVYVIFYFIWLRFE
                     WPHYLLYILLVLGALSTLKLFIKPLWQYHCRFYQVDQLSVQYRTSFLIYKEETSRIER
                     LQYLSIKSNPISKVLNLYKVGFMTAGHTINLPMMSHDDVKIIEARAMSNLRGVESDV"
     gene            complement(6154..6714)
                     /locus_tag="RPH49_000491"
     CDS             complement(6154..6714)
                     /locus_tag="RPH49_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDY5123682.1"
                     /translation="MNTIRNSICLTIITIVLCGFLFPLAITLIGQIFFYQQANGSLIT
                     YDNRIVGSKLIGQHWTERRYFYGRPSAVDYNMNPEKLYKNGVSSGGSNESNGNNELIA
                     RVKHHVKFGNSNVTIDAATSSGSGLDPHITVENALKQAPRIADVRHISTSRVADLIQH
                     RKQRGVLTNDYVNVLELNIALDNMKD"
     gene            complement(6734..8761)
                     /gene="kdpB"
                     /locus_tag="RPH49_000492"
     CDS             complement(6734..8761)
                     /gene="kdpB"
                     /locus_tag="RPH49_000492"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDY5123683.1"
                     /translation="MHHVNKYFNQTMVIEALKMSFYKLNPKQLIKNPIMFVVEVGMIL
                     TLILICFPDIFGTSYLSRGYLITIFIILLITILFANFSEAFAEGRGKAQADSLRQAQS
                     NLTARLIEENGAYRIVNATELKAGQNIRVENGETIPADGVVINGLATVDESAITGESA
                     PVIKESGGDFDGVIGGTLVTSDWLEIRVESEAGTSFLDKMIALVEGAERNKTPNEIAL
                     FTLLTTLTIIFLVVIETLYPIASYLHLILPIAMLIALTVCLIPTTIGGLLSAIGIAGM
                     DRVTQFNVLAKSGRAVEVCGDVDVMILDKTGTITYGNRIASEFLPVNQQMLEKLIVAA
                     YMSSIYDDTPEGKSIVRLAKQMYINELPKDIDGTYKPFTAETRMSGIITNEISVFKGA
                     PNSMINLVKQQQGNIPLNIESLCMDVSSKGGTPLIVIENNVMLGVIYLKDVIKDGLVE
                     RFTELRKMGIETVMCTGDNALTAATIAKEAGVDRFVAECKPEDKIKVIKDEQAKGHIV
                     AMTGDGTNDAPALAQANIGLAMNSGTISAKEAANLIDLDSNPTKLIEVVKIGKQLLMT
                     RGALTTFSLANDVAKYFAILPALMMSTIPEMTSLNIMHLSSPKSAIISALIFNALIIV
                     ALIPIAMKGVKVKGYSIDRIFINNMLIYGLGGLIVPFLGIKLIDMIVQFFV"
     gene            complement(8780..10456)
                     /gene="kdpA"
                     /locus_tag="RPH49_000493"
     CDS             complement(8780..10456)
                     /gene="kdpA"
                     /locus_tag="RPH49_000493"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit A"
                     /protein_id="HDY5123684.1"
                     /translation="MEIILFLTMMVMITYVFSGYLYRVALVQSSRVDLIFTRFENMCF
                     KIIGTDLEHMSAKTYVKHFLAFNGFMGGISFVLLIVQQWLFLNPNHNLNQSIDLAFNT
                     AISFLTNSNLQHYNGESGVTYLTQMIVMTYLMFTSSASGYAVCITMLRRLTGLTNIIG
                     NFYQDIVRFIVRVLLPLSCLISILLMTQGVPQTLHANLMIRTLSGHIQHIAFGPIASL
                     ESIKHLGTNGGGFLAGNSATPFENPNIWSNFIEMGSMMLLPMSMLFLFGRMLSRHGKR
                     VHRHALILFVAMFFIFIAILTLTMWSEYRGNPILANLGIYGPNMEGKEVRFGAGLSAL
                     FTVITTAFTTGSVNNMHDSLTPLGGLGPMVLMMLNVVFGGEGVGLMNLLIYVLLTVFI
                     CSLMVGKTPEYLNMPIGAREMKCIVLVFLIHPILSLVFSALAFMIPGASESITNPSFH
                     GISQVMYEMTSAAANNGSGFEGLKDDTTFWNISTGIIMLLSRYIPIILQLMIASSLVN
                     KKSYHQDKYTIAIDKPYFGVSLIVFIVLLSGLTFIPVLLLGPIGEFLTLK"
     gene            complement(10480..10590)
                     /gene="kdpF"
                     /locus_tag="RPH49_000494"
     CDS             complement(10480..10590)
                     /gene="kdpF"
                     /locus_tag="RPH49_000494"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDY5123685.1"
                     /translation="MLLCCKEVMAMLIVLLLVVIALVLYLFYALIRSEKF"
     gene            10728..13385
                     /locus_tag="RPH49_000495"
     CDS             10728..13385
                     /locus_tag="RPH49_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase KdpD"
                     /protein_id="HDY5123686.1"
                     /translation="MSNTESLNIGKKRGSLTIYIGYSPGVGKTFEMLSNAIELFQSNV
                     DIKIGYIEPHQRDETNALAEQLPKIATNFTKHGSHHFQYLDVDRIIKESPTIVLIDEL
                     AHTNISRDRHEKRYMDIEEILNHGIDVHTTLNIQHIESLSSQIELMTGVHVKERVPDY
                     FIMSADVLEVVDISPEQLIKRLKAGKVYKKDRLDVAFSNFFTYTHLSELRTLTLRTVA
                     DLMSDKEKVRHNHKTSLKPHIAVAISGSIYNEAVIKEAFHIAQKEHAKFTAIYIDVFE
                     KNRQYKDSQKQVHQHLMLAKSLGAKVKVVYSQTVALGLDEWCKNQDVTKLIIGQHIRN
                     KWRDFFNTPLIDHLMSFEHSYKIEIVPIKQIPVELKMNKSPYRPKGKRFAIDMLKMIL
                     IQIICVMMGLWIYQLDKHESSTIILMIFLIGIILLSIWTRSYIIGFLAAIINVFVFNY
                     FFTEPRYTFEVYRFDYPITFIVSILTSILTSALLKQIKFQYSITKKQLYRTDLLFQFN
                     DSIKQTYTVENLLINAGYQINQLLQQSITVYVINQSKVIKTIPLQNHIDNTTQQHEQA
                     LSWVIKNERQAGATTDTFPGINKWLIPIGTSPIKGILAIDYQSSQVINPYDASILESM
                     LNELSLAVENVSLLKQTRESMLQAERQLTHSNFLRSISHDIRTPLTTIMGNLDILVSH
                     SKDMSIIEKEQLLVHSFQESQYLYLLVTNILSLTKLQSSNVQIKLQPYLVSELVEEID
                     MILERRHLKKRITVSSSVDLQFIHIDSKLILQALFNLIENAVKHTSTDTKINLSIRYA
                     SDEQIEFAVIDEGPGISLEEQQKIFEPFYTGSNKYFKDNQKESMGLGLYLVQTILHKH
                     QSNLQYKPNQPHGSIFYFNIDTDFNEGDI"
     gene            13385..14080
                     /locus_tag="RPH49_000496"
     CDS             13385..14080
                     /locus_tag="RPH49_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5123687.1"
                     /translation="MQSKILIIEDDHAITHLLDVALTLDYYNVTTADNATQAHFKIQI
                     DKPDVILLDLGLPDKDGLCLISEIRQHTDIPIIVISARQEEQTIIQALDNGANDYMTK
                     PFNVDELRARIRVIERIAKSHQETNIVFTNGLLSIDFGSKSVVINNQEVHLTPNEFSL
                     LELLSNHKGKVLTYEMILKRIYGYVNKTEMPSLRVHMTSLRQKLSQCHEDAKDIIKTH
                     PRIGYQMLQWKEK"
     gene            complement(14449..15969)
                     /locus_tag="RPH49_000497"
     CDS             complement(14449..15969)
                     /locus_tag="RPH49_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDY5123688.1"
                     /translation="MQNFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILG
                     QAQTGTGKTGAFGIPLIEKVVGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVT
                     VFGGMPIERQIKALKKGPQIVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGF
                     IDDMRFIMDKIPAVQRQTMLFSATMPKAIQALVQQFMKSPKIIKTMNNEMSDPQIEEF
                     YTIVKELEKFDTFTNFLDVHQPELAIVFGRTKRRVDELTSALISKGYKAEGLHGDITQ
                     AKRLEVLKKFKNDQINILVATDVAARGLDISGVSHVYNFDIPQDTESYTHRIGRTGRA
                     GKEGIAVTFVNPIEMDYIRQIEDANGRKMSALRPPHRKEVLQAREDDIKEKVENWMSK
                     ESESRLKRISTELLNEYNDVDLVAALLQELVEANDEVEVQLTFEKPLSRKGRNGKPSG
                     SRNRNSKRGNPKFDSKSKRSKGYSSKKKSTKKFDRKEKSSGGSRPMKGRTFADHQK"
     gene            complement(16485..17843)
                     /locus_tag="RPH49_000498"
     CDS             complement(16485..17843)
                     /locus_tag="RPH49_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDY5123689.1"
                     /translation="MINVTLKQIQSWIPCEIEDQFLNQEINGVTIDSRAISKNMLFIP
                     FKGENVDGHRFVSKALQDGAGAAFYQRGTPIDENVSGPIIWVEDTLTALQQLAQAYLR
                     HVNPKVIAVTGSNGKTTTKDMIESVLHTEFKVKKTQGNYNNEIGLPLTILELDNDTEI
                     SILEMGMSGFHEIEFLSNLAQPDIAVITNIGESHMQDLGSREGIAKAKSEITIGLKDN
                     GTFIYDGDEPLLKPHVKEVENVKCISIGVAADNALVCSVDDRDTTGISFTINNKEHYD
                     LPILGKHNMKNATIAIAVGHELGLTYNTIYQNLKNVSLTGMRMEQHTLENDITVINDA
                     YNASPTSMRAAIDTLSTLTGRRILILGDVLELGENSKEMHISVGNYLEEKHIDVLYTF
                     GNEAKYIYDSGQQHVEKAQHFNSKDDMIEVLTSDLKAHDRVLVKGSRGMKLEEVVNAL
                     IS"
     gene            complement(17858..18928)
                     /locus_tag="RPH49_000499"
     CDS             complement(17858..18928)
                     /locus_tag="RPH49_000499"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDY5123690.1"
                     /translation="MTKENICIVFGGKSAEHEVSILTAQNVLNAIDKDKYHVDIIYIT
                     NDGDWRKQNNITAEIKSTDELHLENGEALEISQLLKESSSGQPYDAVFPLLHGPNGED
                     GTIQGLFEVLDVPYVGNGVLSAASSMDKLVMKQLFEHRGLPQLPYISFLRSEYEKYEH
                     NILKLVNDKLNYPVFVKPANLGSSVGISKCNNEAELKEGIKEAFQFDRKLVIEQGVNA
                     REIEVAVLGNDYPEATWPGEVVKDVAFYDYKSKYKDGKVQLQIPADLDEDVQLTLRNM
                     ALEAFKATDCSGLVRADFFVTEDNQIYINETNAMPGFTAFSMYPKLWENMGLSYSELI
                     TKLIELAKERHQDKQKNKYKID"
     gene            19246..20448
                     /locus_tag="RPH49_000500"
     CDS             19246..20448
                     /locus_tag="RPH49_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="HDY5123691.1"
                     /translation="MNYSSRQQPDKHWLRKVDWVLVATIAVLAIFSVLLINSAMGGGQ
                     YSANFGIRQIFYYILGAIFAGIIMFISPKKIKHYTYLLYFLICLLLIGLLVIPESPIT
                     PIINGAKSWYTFGPISIQPSEFMKIILILALARVVSRHNQFTFNKSFQSDLLLFFKII
                     GVSLVPSILILLQNDLGTTLVLAAIIAGVMLVSGITWRILAPIFITGIVGAMTVILGI
                     LYAPSLIENLLGVQLYQMGRINSWLDPYTYSSGDGYHLTESLKAIGSGQLLGKGYNHG
                     EVYIPENHTDFIFSVIGEELGFIGSVILILIFLFLIFHLIRLAAKIEDQFNKIFIVGF
                     VTLLVFHILQNIGMTIQLLPITGIPLPFISYGGSALWSMMTGIGIVLSIYYHEPKRYV
                     DLYHPKSN"
     gene            complement(20712..20849)
                     /locus_tag="RPH49_000501"
     CDS             complement(20712..20849)
                     /locus_tag="RPH49_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123692.1"
                     /translation="MKRPEKIQNVVKLLSSLGVNIKKTKSRLDIINTLPASNKVSHEL
                     K"
     gene            complement(20977..21186)
                     /locus_tag="RPH49_000502"
     CDS             complement(20977..21186)
                     /locus_tag="RPH49_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDY5123693.1"
                     /translation="MIHQNTIYTAGIETEEQVSQLTERISNMIGVHQVNINIIDGQVT
                     VSYETPANLNSIEKEIYDEGYKIVF"
     gene            complement(21198..21491)
                     /gene="csoR"
                     /locus_tag="RPH49_000503"
     CDS             complement(21198..21491)
                     /gene="csoR"
                     /locus_tag="RPH49_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-sensing transcriptional repressor CsoR"
                     /protein_id="HDY5123694.1"
                     /translation="MTEQDIAHHSEQIKTNLKSRLNRIEGQVRAINRMIEEDVYCDDV
                     LTQIRATRSALNSVATKLLEQHMKSCIMNKVNQGAQEEAMEELLVTFQKLIKD"
     gene            21657..23141
                     /gene="cls"
                     /locus_tag="RPH49_000504"
     CDS             21657..23141
                     /gene="cls"
                     /locus_tag="RPH49_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDY5123695.1"
                     /translation="MIELLSIALKHSNIILNSIFIGAFILNLLFAFTIIFMERRSANS
                     IWAWLLVLVFLPLFGFILYLLLGRQIQRDQIFKIDKEDKKGLELIVDEQLAALKNENF
                     SNSNYQIVKFKEMIQMLLYNNAAFLTTDNDLKIYTDGQEKFDDLIQDIRNATDYIHFQ
                     YYIIQNDELGRTILNELGKKAEQGVEVKILYDDMGSRGLRKKGLRPFRNKGGHAEAFF
                     PSKLPLINLRMNNRNHRKIVVIDGQIGYVGGFNVGDEYLGKSKKFGYWRDTHLRIVGD
                     AVNALQLRFILDWNSQATRDHISYDDRYFPDVNSGGTIGVQIASSGPDEEWEQIKYGY
                     LKMISSAKKSIYIQSPYFIPDQAFLDSIKIAALGGVDVNIMIPNKPDHPFVFWATLKN
                     AASLLDAGVKVFHYDNGFLHSKTLVIDDEIASVGTANMDHRSFTLNFEVNAFIYDQQI
                     AKKLKQAFIDDLAVSSELTKERYAKRSLWIKFKEGISQLLSPIL"
     gene            23169..23816
                     /locus_tag="RPH49_000505"
     CDS             23169..23816
                     /locus_tag="RPH49_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDY5123696.1"
                     /translation="MQQSDIISAAKKYMESIHQNDYTGHDIAHVYRVTALAKSIAENE
                     GVNDTLVIELACLLHDTVDEKVVDANKQYVELKSFLSSLSLSTEDQEHILFIINNMSY
                     RNGKNDHVTLSLEGQIVRDADRLDAIGAIGVARTFQFAGHFGEPMWTEHMSLDKINDD
                     LVEQLPPSAIKHFFEKLLKLESLMHTDTAKMIAKERQDFMMMYLKQFFTEWNYHD"
     gene            complement(24294..25166)
                     /gene="yidC"
                     /locus_tag="RPH49_000506"
     CDS             complement(24294..25166)
                     /gene="yidC"
                     /locus_tag="RPH49_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDY5123697.1"
                     /translation="MKKKALLPLFLGIMVFLAGCDYSKPEKRSGFFYNTFVDPMKNVL
                     DWLGNNLLNDNYGLAIIILVLVIRIILLPFMLSNYKNSHMMRQKMKVAKPEVEKIQEK
                     VKRARTQEEKMAANQELMQVYKKYDMNPIKSMLGCLPMLIQLPIIMGLYFVLKDQLVD
                     GLFKYPHFLWFDLGRPDIWITIIAGVLYFIQAYVSSKTMPDEQRQMGYMMMVISPIMI
                     IWISLSSASALGLYWSVSAAFLVVQTHFANIYYEKVAKKEVQPFIEAYEREHNGGSNK
                     KGKNTQVVSKKKKK"
     gene            complement(25252..25893)
                     /locus_tag="RPH49_000507"
     CDS             complement(25252..25893)
                     /locus_tag="RPH49_000507"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDY5123698.1"
                     /translation="MFNQSYLNVYFICGTSDVPSHRTIHEVLEAALKAGITLFQFREK
                     GESALKGNDKLVLAKELQHLCHQYDVPFIVNDDVSLAKEINADGIHVGQDDAKVKEIA
                     QYFTDKIIGLSISDLDEYAKSDLTHVDYIGVGPIYPTPSKHDAHIPVGPEMIATFKEM
                     NPQLPIVAIGGINTNNVAPIVEAGANGISVISAISKSENIEKTVNRFKDFFNN"
     gene            complement(25895..26686)
                     /gene="thiM"
                     /locus_tag="RPH49_000508"
     CDS             complement(25895..26686)
                     /gene="thiM"
                     /locus_tag="RPH49_000508"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDY5123699.1"
                     /translation="MNYLNKIRIENPLTICYTNDVVKNFTANGLLSIGASPAMSEAPE
                     EAEEFYKVAQALLINIGTLTAENEQDIIAIAQTANEAGLPIVFDPVAVGASTYRKQFC
                     KLLLKSAKVSVIKGNASEILALIDDTATMKGTDSDANLDAVTIAKKAYATYKTAIVIT
                     GKEDVIVQDNKAIVLANGSPLLARVTGAGCLLGGVIAGFLFRETEPDIEALIEAVSVF
                     NIAAEVAAENENCGGPGTFSPLLLDTLYHLNETTYQQRIRIQEVE"
     gene            complement(26670..27500)
                     /gene="thiD"
                     /locus_tag="RPH49_000509"
     CDS             complement(26670..27500)
                     /gene="thiD"
                     /locus_tag="RPH49_000509"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDY5123700.1"
                     /translation="MIKPKIALTIAGTDPTGGAGVMADLKSFHSCGVYGMGVVTSIVA
                     QNTLGVQHIHNLNHQWVDEQLDSVFNDTLPHAIKTGMIATADTMETIRHYLMQHESIP
                     YVIDPVMLAKSGDSLMDNDTKQNLQHTLLPLADVVTPNLPEAEEITGLTIDSEEKIMQ
                     AGRIFINEIGSKGVIIKGGHSNDTDIAKDYLFTNEGVQTFENERFKTKHTHGTGCTFS
                     AVITAELAKGRPLFEAVHKAKKFISMSIQYTPEIGRGRGPVNHFAYLKKEGLDDELSK
                     "
     gene            complement(27493..28182)
                     /gene="tenA"
                     /locus_tag="RPH49_000510"
     CDS             complement(27493..28182)
                     /gene="tenA"
                     /locus_tag="RPH49_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HDY5123701.1"
                     /translation="MEFSQKLYQAAKPIINDIYEDDFIQKMLLGNIQADALRHYLQAD
                     AAYLKEFTNLYALLIPKMNSMNDVKFLVEQIEFMVEGEVLAHDILAQIVGESYEEIIK
                     TKVWPPSGDHYRKHMYFQAHSRENAIYTIAAMAPCPYIYAELAKRSQSDHKLNREKDT
                     AKWFDFYSTEMDDIINVFEALMNKLAESMSDKELEQVKQVFLESCIHERRFFNMAMTL
                     EQWEFGGKVND"
     regulatory      complement(28262..28364)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(28569..29264)
                     /gene="sceD"
                     /locus_tag="RPH49_000511"
     CDS             complement(28569..29264)
                     /gene="sceD"
                     /locus_tag="RPH49_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase SceD"
                     /protein_id="HDY5123702.1"
                     /translation="MKKTLLASSLAVGLGIVAGNAGHEAHASEADLNKASLAQMAQSN
                     DQTLNQKPIEAGAYNYTFDYEGFTYHFESDGTHFAWNYHATGANGADMSAQAPATNNV
                     APSAVQANQVQSQEVEAPQNAQTQQPQASTSNNSQVTATPTESKASEGSSVNVNDHLK
                     QIAQRESGGNIHAVNPTSGAAGKYQFLQSTWDSVAPAKYKGVSPANAPESVQDAAAVK
                     LYNTGGAGHWVTA"
     gene            complement(29653..30048)
                     /locus_tag="RPH49_000512"
     CDS             complement(29653..30048)
                     /locus_tag="RPH49_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDY5123703.1"
                     /translation="MLNKIVIVGRLTKDAQIFEKEDRKIATFCVATHRNYKDENGEIV
                     CDYLFCKAFGKLASNIEKYTNQGTLVGITGQMRSRKYDKDGQTHFVTELYVETIKFMS
                     PKSQNNEILSDSILDIDSQNIDNHDLLEI"
     gene            30242..30682
                     /locus_tag="RPH49_000513"
     CDS             30242..30682
                     /locus_tag="RPH49_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwpF-like family protein"
                     /protein_id="HDY5123704.1"
                     /translation="MKTFKAVRFQIVNEHGRIIEYELEDGVIINKEESGTGWLLEIVI
                     SNEHYETFKEYQDSEQLLDIRVVITRPANDPALFESTVKSIKNFKTTMSIVFECHIYT
                     LRQQYAESLLEQLIDDGLSGEELKKSFNRMMQSKPKLKDEKLEE"
     gene            complement(30740..31180)
                     /gene="fabZ"
                     /locus_tag="RPH49_000514"
     CDS             complement(30740..31180)
                     /gene="fabZ"
                     /locus_tag="RPH49_000514"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDY5123705.1"
                     /translation="METIFDYNQIKQIIPHRQPFLLIDKVVEYEEGQRCVAIKQVSGN
                     EPFFQGHFPEYAVMPGVLITEALAQTGAVAILNSEENKGKIALFAGIDKCRFKRQVVP
                     GDTLTLEVEITKIKGPIGKGNAKATVDGQLACSCELTFAIQDVK"
     gene            complement(31214..32479)
                     /gene="murA"
                     /locus_tag="RPH49_000515"
     CDS             complement(31214..32479)
                     /gene="murA"
                     /locus_tag="RPH49_000515"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDY5123706.1"
                     /translation="MDKIVIKGGNKLTGEVKVEGAKNAVLPILTASLLASDKPSKLVN
                     VPALSDVETINNVLTTLNADVTYKKDENAVVVDATKTLNEEAPYEYVSKMRASILVMG
                     PLLARLGHAIVALPGGCAIGSRPIEQHIKGFEALGAEIHLENGNIYANAKDGLKGTSI
                     HLDFPSVGATQNIIMAASLAKGKTLIENAAKEPEIVDLANYINEMGGRITGAGTDTIT
                     INGVESLHGVEHAIIPDRIEAGTLLIAGAITRGDIFVRGAIKEHMASLVYKLEEMGVE
                     LDYQEDGIRVRAEGELQPVDIKTLPHPGFPTDMQSQMMALLLTANGHKVVTETVFENR
                     FMHVAEFKRMNANINVEGRSAKLEGKSQLQGAQVKATDLRAAAALILAGLVADGKTSV
                     TELTHLDRGYVDLHGKLKQLGADIERIND"
     gene            complement(32590..32823)
                     /locus_tag="RPH49_000516"
     CDS             complement(32590..32823)
                     /locus_tag="RPH49_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDY5123707.1"
                     /translation="MDYIGQYAVIHLVLHVVCICIAYWALQSIRLDQFFKKGYATQLQ
                     VCMIFVAILLGTAVSNFIVDLLQYSTQVKYLIK"
     gene            complement(32955..33047)
                     /locus_tag="RPH49_000517"
     CDS             complement(32955..33047)
                     /locus_tag="RPH49_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123708.1"
                     /translation="MLKSKFPSPLSTVDISFFESSYIFSCQDTL"
     gene            complement(33499..33903)
                     /locus_tag="RPH49_000518"
     CDS             complement(33499..33903)
                     /locus_tag="RPH49_000518"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDY5123709.1"
                     /translation="MNTLNLDIVTPNGSVYNRDNVELVVMQTTAGEIGVMSGHIPTVA
                     ALKTGFVKVKFHDGTEYIAVSDGFVEVRKDKVSIIVQTAETAREIDVERAKLAKARAE
                     SHLENDDDNTDIHRAERALERANNRLRVAELK"
     gene            complement(33923..35335)
                     /gene="atpD"
                     /locus_tag="RPH49_000519"
     CDS             complement(33923..35335)
                     /gene="atpD"
                     /locus_tag="RPH49_000519"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDY5123710.1"
                     /translation="MGIGRVTQVMGPVIDVRFEHNEVPKINNALVIDVPKEEGTIQLT
                     LEVALQLGDDVVRTIAMDSTDGVQRGMDVKDTGKEISVPVGDETLGRVFNVLGETIDL
                     KEEISDSVRRDPIHRQAPAFDELSTEVQILETGIKVVDLLAPYIKGGKIGLFGGAGVG
                     KTVLIQELINNIAQEHGGISVFAGVGERTREGNDLYFEMSDSGVIKKTAMVFGQMNEP
                     PGARMRVALSGLTMAEYFRDEQGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTTKGSVTSIQAVFVPADDYTDPAPATAFAHLDATTNLERKLTE
                     MGIYPAVDPLASTSRALEPSIVGQEHYEVARDVQSTLQKYRELQDIIAILGMDELSDE
                     DKQTVERARRIQFFLSQNFHVAEQFTGQKGSYVPVKTTVANFKDILDGKYDHIPEDAF
                     RLVGSMDDVIAKAKDMGVEV"
     gene            complement(35357..36223)
                     /locus_tag="RPH49_000520"
     CDS             complement(35357..36223)
                     /locus_tag="RPH49_000520"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500821.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDY5123711.1"
                     /translation="MASLKEIDTRIKSTKKMKQITKAMNMVSSSKLRRAEKNTKQFTP
                     YMDKMQDAITAVAGASSNTNHPMLRPRKITRSGYLVITSDKGLAGAYSANVLKKLITD
                     IEAKHQDSSEYSIVVLGQQGVDFLKNRGYDIEYSQVDVPDQPSFKSVQALANHAIDLY
                     SEEEIDELNIYYSHYVSVLENKPTSRQVLPLSQEDSSKGHGHLSSYEFEPDKESILSV
                     ILPQYVESLIYGTILDAKASEHATRMTAMKNATDNATELIDDLSLEYNRARQAEITQQ
                     ITEIVGGSAALE"
     gene            complement(36254..37762)
                     /locus_tag="RPH49_000521"
     CDS             complement(36254..37762)
                     /locus_tag="RPH49_000521"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDY5123712.1"
                     /translation="MAIKAEEISALLRSQIENYESEMSVTDVGTVLQIGDGIALIHGL
                     NDVMAGELVEFHNGVLGLAQNLEESNVGVVILGPYTGITEGDEVKRTGRIMEVPVGEE
                     LIGRVVNPLGQPIDGQGPINTTKTRPVEKKATGVMDRKSVDEPLQTGIKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQGTICIYVAIGQKDSTVRANVEKLRQAGAL
                     DYTIVVAASASEPSPLLYIAPYSGVTMGEEFMFNGKHVLIVYDDLTKQAAAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLNDDLGGGSITALPIIETQAGDISAYVPTNV
                     ISITDGQIFLQSDLFFSGVRPAINAGQSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     ESFAQFGSDLDEFTASKLERGKRTVEVLKQDQNKPLPVEHQVLIIYALTKGYLDDIPV
                     VDITRFEDELNHWAESNATELLNEIRETGGLPDAEKFDTAINEFKKSFSKSE"
     gene            complement(37784..38323)
                     /locus_tag="RPH49_000522"
     CDS             complement(37784..38323)
                     /locus_tag="RPH49_000522"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDY5123713.1"
                     /translation="MVKVANKYAKALFDVSLDTNNLETINQELTVINEAVKDKIEQLK
                     MVDSNPTQTAEQRRELINGVFTDINPYIKNMMYVLADNRHISLIADVFKAFQSLYNGH
                     YNQDFATIESTYELSQEELDKIVKLVTQQTKLSKVIVDTKINPDLIGGFRVKVGTTVL
                     DGSVRNDLVQLQRKFRRVN"
     gene            complement(38323..38844)
                     /locus_tag="RPH49_000523"
     CDS             complement(38323..38844)
                     /locus_tag="RPH49_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDY5123714.1"
                     /translation="MTETANLFVLGAAGGVEWGTVIVQVLTFIVLLALLKKFAWGPLK
                     DVMDKRERDINRDIDDAEQAKLNAQKLEEENKQKLKETQEEVQKILEDAKVQARQQQE
                     QIIHEANVRANGMIETAQSEINSQKERAIADINNQVSELSVLIASKVLRKEISEQDQK
                     ALVDKYLKEAGDK"
     gene            complement(39042..39254)
                     /gene="atpE"
                     /locus_tag="RPH49_000524"
     CDS             complement(39042..39254)
                     /gene="atpE"
                     /locus_tag="RPH49_000524"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDY5123715.1"
                     /translation="MNLIAAAIAIGLSALGAGIGNGLIVSRTVEGVARQPEARGQLMG
                     IMFIGVGLVEALPIIGVVIAFMTFAG"
     gene            complement(39298..40026)
                     /gene="atpB"
                     /locus_tag="RPH49_000525"
     CDS             complement(39298..40026)
                     /gene="atpB"
                     /locus_tag="RPH49_000525"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDY5123716.1"
                     /translation="MDHKSPLVSWNLFGFDIVFNLSSILMILVTAFLVFLLAIICTRN
                     LKKRPTGKQNFVEWIFDFVRGIIEGNMAWKKGGQFHFLAVTLILYIFIANMLGLPFSI
                     VTKDHTLWWKSPTADATVTLTLSTTIILLTHFYGIKMRGTKQYLKGYVQPFWPLAIIN
                     VFEEFTSTLTLGLRLYGNIFAGEILLTLLAGLFFNEPAWGWIISIPGLIVWQAFSIFV
                     GTIQAYIFIMLSMVYMSHKVADEH"
     gene            complement(40047..40499)
                     /locus_tag="RPH49_000526"
     CDS             complement(40047..40499)
                     /locus_tag="RPH49_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase subunit I"
                     /protein_id="HDY5123717.1"
                     /translation="MNRIDTTNRLYYHLVCMSGTVFMIDISHTEAYKMSRFYNIFKQF
                     IQYYLYLLIILGGLYLFTHHAFILGLIIGVTGSAINTVIFESYLAKAKRPDTMHISTG
                     NMWRYLVAIIACMIWYFNKSHVSIIGIIIGLMISYVVVIIHPLLKVSK"
     gene            complement(40567..41694)
                     /gene="wecB"
                     /locus_tag="RPH49_000527"
     CDS             complement(40567..41694)
                     /gene="wecB"
                     /locus_tag="RPH49_000527"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDY5123718.1"
                     /translation="MKKIMTIFGTRPEAIKMAPLVKALEQEKMLEPIVVVTAQHREML
                     DSVLSTFEIKPKYDLNIMKSGQTLSEITSKSITQLEQVIQLEKPDMVLVHGDTMTTFA
                     GGLAAFYNQVPIGHVEAGLRSYDKYSPFPEEVNRQLVGVLADLHFAPTKNAASHLLSE
                     GKYSESVVVTGNTAIDAMKYTVDDNYKSNIMDKYHDKKFILMTAHRRENIGQPMENIF
                     KAVRRLIDEYTDLALVYPMHKNPKVREVAQKILGSHDRIELIEPLDVVDFHNFAKKSY
                     FILTDSGGIQEEAPSFNKPVLVLRSVTERPEGVEAGTLKVIGTNKQNVYQAAKELIDD
                     ERLYHQMSEASNPYGDGFASERIVNHIKYYLNLITEKPSDF"
     gene            complement(41718..42347)
                     /gene="upp"
                     /locus_tag="RPH49_000528"
     CDS             complement(41718..42347)
                     /gene="upp"
                     /locus_tag="RPH49_000528"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017636774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDY5123719.1"
                     /translation="MSKVHVFDHPLIQHKLSYIRDVNTGTKEFRELVDEVGMLMAYEV
                     TRDLELQDVDIETPVTKMTAKRLAGKKLAIVPILRAGLGMTDGILSLVPAARVGHIGL
                     YRDPETLKAVEYFAKLPQDITERQIIVVDPMLATGASAIEAITSLKKRGAKNIRFMCL
                     IAAPEGVEKMHEAHPDVDIYIAALDEKLNDKAYITPGLGDAGDRLFGTK"
     gene            complement(42375..43613)
                     /locus_tag="RPH49_000529"
     CDS             complement(42375..43613)
                     /locus_tag="RPH49_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDY5123720.1"
                     /translation="MSYITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQG
                     SVLTNKYAEGYPGRRYYGGCEFVDVTESIAINRAKALFGAEHVNVQPHSGSQANMAVY
                     LVALEMGDTVLGMNLSHGGHLTHGAPVNFSGKFYNFVEYGVDKDTERINYDEVRKLAL
                     EHKPKLIVAGASAYSRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYAD
                     FVTTTTHKTLRGPRGGMILCKEEYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALEN
                     NFKTYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDS
                     VGITCNKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKDEE
                     KLQQAKERVAKLTAEYPLYQ"
     gene            complement(43640..44164)
                     /locus_tag="RPH49_000530"
     CDS             complement(43640..44164)
                     /locus_tag="RPH49_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDY5123721.1"
                     /translation="MKDLTMLLDELKDMSFFNKGDICLIGCSTSEVIGEKIGTVGSME
                     VAETIFNALDVVSKETGVTFAFQGCEHINRAITIEKSQYNPLTMEEVSVVPNVHAGGS
                     LATYAFQHMKDPIVVEHITVPCGIDIGQTLIGMHIKHVCVPVRTSVKQVGQAIVTIAT
                     SRPKKIGGERAKYQ"
     gene            complement(44271..44690)
                     /locus_tag="RPH49_000531"
     CDS             complement(44271..44690)
                     /locus_tag="RPH49_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight protein arginine
                     phosphatase"
                     /protein_id="HDY5123722.1"
                     /translation="MKILFVCTGNTCRSPLAESIAKEVMPNHQFESRGIFAVNNQGVS
                     NYVEDIVEEHHLAETTLSQQFTEADLKADIILTMSYSHKELIEAQFGLQNHVFTLHEY
                     VKEAGEVIDPYGGTKEMYVHTYEELVSLILKLKDIIC"
     gene            complement(44687..45733)
                     /locus_tag="RPH49_000532"
     CDS             complement(44687..45733)
                     /locus_tag="RPH49_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDY5123723.1"
                     /translation="MDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGL
                     AANATDEEAVAKIYEAKGRPSDNPLIVHIHSKDQLKDFTYILDAPVEKLMQAFWPGPI
                     SFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTT
                     FNHVYQDLNGRIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITDILPNSI
                     THADYNDTEQPIAPGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAF
                     IPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRM
                     LKAAGNHIVKGCEL"
     gene            complement(45817..46653)
                     /gene="prmC"
                     /locus_tag="RPH49_000533"
     CDS             complement(45817..46653)
                     /gene="prmC"
                     /locus_tag="RPH49_000533"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDY5123724.1"
                     /translation="MVNYKEKLDEAIHLTQQKGFEQTRAEWLMLDVFQWTRTDFVVHM
                     HDDMPKAMIMKFDLALQRMLLGEPIQYIVGFASFYGRTFDVNSNCLIPRPETEEVMLH
                     FLQQLEDDATIVDIGTGSGVLAITLKCEKPDLNVIATDISLEAMNMARNNAEKHQSQI
                     QFLTGDALKPLINEGIKLNGLISNPPYIDEKDMVTMSPTVTRFEPHQALFADNHGYAI
                     YESIIEDLPHVMEKGSPVVFEIGYNQGEALKSIILNKFPDKKIDIIKDINGHDRIVSF
                     KW"
     gene            complement(46640..47716)
                     /gene="prfA"
                     /locus_tag="RPH49_000534"
     CDS             complement(46640..47716)
                     /gene="prfA"
                     /locus_tag="RPH49_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015445905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDY5123725.1"
                     /translation="MFDQLDIVEERYEQLNELLSDPDVVNDSDKLRKYSKEQADLQKT
                     VDVYRNYKAKKEELADIEEMLSETDDKEEVEMLKEESNGIKAELPNLEEELKILLIPK
                     DPNDDKDVIVEIRAAAGGDEAAIFAGDLMRMYSKYAESQGFKTEIVEASESDHGGYKE
                     ISFSVSGNGAYSKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEVEDVEIEIRNE
                     DLKIDTYRSSGAGGQHVNTTDSAVRITHLPTGVIATSSEKSQIQNREKAMKVLKARLY
                     DMKVQEEQQKYASQRKSAVGTGDRSERIRTYNYPQSRVTDHRIGLTLQKLGQIMEGHL
                     EEIIDALTLSEQTDKLKELNNGEL"
     gene            complement(47717..48316)
                     /locus_tag="RPH49_000535"
     CDS             complement(47717..48316)
                     /locus_tag="RPH49_000535"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDY5123726.1"
                     /translation="MYETYHSGWIECITGSMFSGKSEELIRRLRRGIYAKQKVVVFKP
                     AIDDRYHKEKVVSHNGNAIEAINISKASEIMTHDLTNVDVIGIDEVQFFDDEIVSIVE
                     KLSADGHRVIVAGLDMDFRGEPFEPMPKLMAVSEQVTKLQAVCAVCGSSSSRTQRLIN
                     GKPAKIDDPIILVGANESYEPRCRAHHIVAPSDNNKEEL"
     gene            complement(48662..48916)
                     /locus_tag="RPH49_000536"
     CDS             complement(48662..48916)
                     /locus_tag="RPH49_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDY5123727.1"
                     /translation="MKQGIHPEYHQVIFLDTTTNFKFLSGSTKTSSEMMEWEDGKEYP
                     VIRLDISSDSHPFYTGRQKFAAADGRVERFNKKFGLKSNN"
     gene            complement(49034..50350)
                     /gene="rho"
                     /locus_tag="RPH49_000537"
     CDS             complement(49034..50350)
                     /gene="rho"
                     /locus_tag="RPH49_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDY5123728.1"
                     /translation="MPERERTSPQYESFHELYKNYTTKELTQKAKTLKLTNYSKLNKK
                     ELVLAIMEAQMEKDGNYYMEGILDDIQPDGYGFLRTVNYSKGEKDIYISASQIRRFEI
                     KRGDKVTGKVRKPKDNEKYYGLLQVDFVNDHNAEEVKKRPHFQALTPLYPDERIKLET
                     ETQNYSTRIMDLVTPIGLGQRGLIVAPPKAGKTSLLKEIANAISTNKPDAKLFILLVG
                     ERPEEVTDLERSVEAAEVVHSTFDEPPEHHVKVAELLLERAKRLVEIGEDVIILMDSI
                     TRLARAYNLVIPPSGRTLSGGLDPASLHKPKAFFGAARNIEAGGSLTILATALVDTGS
                     RMDDMIYEEFKGTGNMELHLDRKLSERRIFPAIDIGRSSTRKEELLISKSELDTLWQL
                     RNLFTDSTDFTERFIRKLKRSKNNEDFFKQLQKSAEESTKTGRPII"
     gene            complement(50597..52024)
                     /locus_tag="RPH49_000538"
     CDS             complement(50597..52024)
                     /locus_tag="RPH49_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="HDY5123729.1"
                     /translation="MRDYTKQYINGEWVESNSNETIEVINPATEEVIGKVAKGNKADV
                     DKAVEAADDVYLEFRHTSVKERQALLDKIVKEYENRKDDIVQAITDELGAPLSLSERV
                     HYQMGLNHFVAARDALDNYEFEERRGDDLVVKEAIGVSGLITPWNFPTNQTSLKLAAA
                     FAAGSPVVLKPSEETPFAAVILAEIFDKVGVPKGVFNLVNGDGAGVGNPLSEHPKVRM
                     MSFTGSGPTGSKIMEKAAKYFKKVSLELGGKSPYIVLDDVDIKEAAKATTGKVVNNTG
                     QVCTAGTRVLVPNKIKDAFLAELKEQFSQVRVGNPREDGTQVGPIISKKQFDQVQNYI
                     NKGIEEGAELFYGGPGKPEGLEKGYFARPTIFINVDNQMTIAQEEIFGPVMSVITYND
                     LDEAIQIANDTKYGLAGYVIGKNKETLHKVARSIEAGTVEINEAGRKPDLPFGGYKQS
                     GLGREWGDYGIEEFLEVKSIAGYFK"
     gene            complement(52262..52597)
                     /locus_tag="RPH49_000539"
     CDS             complement(52262..52597)
                     /locus_tag="RPH49_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5123730.1"
                     /translation="MEVCPYLEETFKILGRSWNGLIINYLSRCNDCSAHFSDMKRDLK
                     TITPRALSLKLSELAQWELVEKQIISTSPVQIIYVLTEKGKALAEALHPIEAWAQSYV
                     DLTDQRTAK"
     gene            complement(52686..53945)
                     /locus_tag="RPH49_000540"
     CDS             complement(52686..53945)
                     /locus_tag="RPH49_000540"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDY5123731.1"
                     /translation="MAQEVIKIRGGRTLNGEVNISGAKNSAVAIIPATLLAQGHVKLE
                     GLPQISDVKTLVSLLEDLNIKASLNGTELEVDTTEIQNAALPNNKVESLRASYYMMGA
                     MLGRFKKCVIGLPGGCPLGPRPIDQHIKGFKALGAEIDESSTTSMKIEAKELKGAHIF
                     LDMVSVGATINIMLAAVYATGQTVIENAAKEPEVVDVANFLTSMGANIKGAGTSTIKI
                     NGVKELHGSEYQVIPDRIEAGTYMCIAAACGENVILNNIVPKHVETLTAKFSELGVNV
                     DVRDERIRINNNAPYQFVDIKTLVYPGFATDLQQPITPLLFMANGPSFVTDTIYPERF
                     KHVEELKRMGANIEVDEGTATIKPSTLHGAEVYASDLRAGACLIIAGLIAEGVTTIYN
                     VKHIYRGYTDIVENLKALGADIWTETV"
     gene            complement(54411..55271)
                     /locus_tag="RPH49_000541"
     CDS             complement(54411..55271)
                     /locus_tag="RPH49_000541"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002468309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDY5123732.1"
                     /translation="MPLVSMKEMLIDAKENGYAVGQYNINNLEFTQAILEASQEENAP
                     VILGVSEGAARYMSGFYTIVKMVEGLMHDLNITIPVAIHLDHGSSFEKCKEAIDAGFT
                     SVMIDASHSPFEENVATTKKVVEYAHEKGVSVEAELGTVGGQEDDVVADGIIYADPKE
                     CQELVEKTGIDALAPALGSVHGPYKGEPKLGFKEMEEIGLSTGLPLVLHGGTGIPTKD
                     IQKAIPFGTAKINVNTENQIASAKAVRDVLNNDKEVYDPRKYLGPAREAIKETVKGKI
                     KEFGTSNRAK"
     gene            55489..56010
                     /locus_tag="RPH49_000542"
     CDS             55489..56010
                     /locus_tag="RPH49_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2529 domain-containing protein"
                     /protein_id="HDY5123733.1"
                     /translation="MSKILNTQLIGIFNRLEKQSLEIQMAAQCLIQAIGGEGYVYVKG
                     YDDLQFFESFILHGDERLKSSRKLDAIKDFKEIDSTDRVLLFAPFYNDQVALDIQKLI
                     DLDIDVVLISNKPKTDDFPDHLVHFIDLSTPRPIVYTEDYDKIVQPHAMALNYVYYDI
                     YTQMIEMTRDLEL"
     gene            complement(56119..57729)
                     /locus_tag="RPH49_000543"
     CDS             complement(56119..57729)
                     /locus_tag="RPH49_000543"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDY5123734.1"
                     /translation="MTKFIFVTGGVVSSLGKGITASSLGRLLKDRGLNVTIQKFDPYL
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKFSNVTAGKVYSHVLKKE
                     RRGDYLGGTVQVIPHITNEIKERLLLAGESTNADVVITEIGGTTGDIESLPFIEAIRQ
                     IRSDLGRENVMYVHCTLLPYIKAAGEMKTKPTQHSVKELRGLGIQPDLIVVRTEYEMT
                     QDLKDKIALFCDINKESVIECRDADSLYEIPLQLSQQNMDDIVIKRLQLNAKYETQLD
                     EWKQLLDIVNNLDGKITIGLVGKYVSLQDAYLSVVESLKHAGYPFAKDIDIRWIDSSE
                     VTDENAAEYLADVDGILVPGGFGFRASEGKISAIKYARENNVPFFGICLGMQLATVEF
                     SRNVLGLEGAHSAELDPATPYPIIDLLPEQKDIEDLGGTLRLGLYPCSIKEGTLAQDV
                     YGKAEIEERHRHRYEFNNDYREQLEANGMVISGTSPDGRLVEMVEIPTNDFFIACQFH
                     PEFLSRPNRPHPIFKSFIEASLKYQQNK"
     gene            complement(58065..58595)
                     /locus_tag="RPH49_000544"
     CDS             complement(58065..58595)
                     /locus_tag="RPH49_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDY5123735.1"
                     /translation="MKIQDYTKQMVDEKSFIDMAYTLLNDKGETMNLYDIIDEFRALG
                     DYEYEEIETRVVQFYTDLNTDGRFLNVGENLWGLRDWYSVDDIEEKIAPTIQKFDILD
                     ADDEEDQNLKLLGEDELDDDDDIPAQTDDQEELNDPEDEQVEEEINHSDIVIEEDEDE
                     LDEDEEDFEDEEDFKA"
     gene            complement(58707..59567)
                     /locus_tag="RPH49_000545"
     CDS             complement(58707..59567)
                     /locus_tag="RPH49_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123736.1"
                     /translation="MAKELCFEGITLKAFDEQYRSAINDFDLNERQQIYSSLPKEVID
                     DAINDADRIANVAINDKNEVVGFFVLHRYYQHEGYDTPENVVYIRSLSINEKYQGFGY
                     GTKIMMSLPQYVQGVFPDFNHLYLVVDAENDNAWNLYERAGFMHTATKEEGPIGKERL
                     YYLDLDSKHVSSLKLEEESRSEVTNVHIINLMIDGQKVGFIALEQIGERMNIAAIEVD
                     KSYRFNGIGSSALRQLPTYLRKNYDNLNVITMILFGENNDFKPLCLNSNFVEIEQTDD
                     YVVFEKYLNY"
BASE COUNT        18645 a        11318 c         8674 g        21002 t
ORIGIN      
        1 tctaaaagtt tttgtttatc tataaaggta ccttcactat ttctagcttc agtcacacca
       61 tccgttaaaa tgataattaa atcatcaagg tatattggaa tttcttgttg ttgatatcgt
      121 gtttgtgaac tgattcctaa cactctacct ctaactgaaa tttcttcaaa ttcttctttt
      181 tcagcgcgat aaatatatcc aggctcatga ccagctgaac tacaatacaa taaatggttc
      241 atttcttcat ataaaccata aaacattgtg acgaacatat tttgattaat attcttttca
      301 acaacacgat ttaaacgttt taagccatca ctcggtaatt gtgagtgtcc ataagaatcc
      361 ataccaaact ttatcatact cattgctaaa gcagctggta taccttttcc aatgacatct
      421 gcaacagcaa agctcattgt gccatcgtta tggtcaatta aattaaaata atctccactt
      481 actttttgtg ctgccactga aataacgcca atttgaatac tatcaaattg tggaatatct
      541 gttttaagca ttgtttgttg taagctagaa gctaagtcta tctctttatc gtgaacttga
      601 agtttatcta ccaatctttg ataatctcga taactataac caaagccttt aacgatttct
      661 tgtaagacat ctaatgtctt gaacacatct tcacgcgtta agtttaacgt caatatatag
      721 tttttgtgaa tatcgacaat gtcttcaggc aagacgtcct tacgaatcac ttcgtcagtg
      781 tatttctcac acttttttat caattctact ttatcttggc acgttaaact ttcatcaatt
      841 aaacccttat aatgttgctt aaattcttcc acgattagtt gcctcctcac ttcccttaca
      901 aagcaaatgc ttaagcaagg ataattatga ttcacttact aacatttatt taattgcact
      961 tatcaatttt gtcgtttgca attttgctgt agatgatact tttaagctaa aaaaaacttt
     1021 aggatggaat acctaaagcc taaaaaactt aagacatcct tttataataa aaaatatgaa
     1081 tatcataact ggtatttgct aaaatcttaa tttataagaa attcttcgca cagaatttag
     1141 aaatagttat aattattata aagttattgt cttttatatc aatattttat ttatctctga
     1201 aaaatacata taatagacgc ctaatttttc tgatgagcta ctgcattcag ccctaaacta
     1261 atcattagtg cattatctac ttctttcatt ttatcatcgg ataaatacgt cagtttttct
     1321 ttcaatcgtt ttttatcaag tgtacgaatt tgttctaata atatgactga gtctttatcc
     1381 aatttatatt ttttcttttc aatctctaca tgtgtcggta ttttcgcttt attaatccta
     1441 ccagttattg ccgcaacaat aactgtagga ctatatttat taccagtgtc attttgaata
     1501 atgactacag gtctgactcc cccttgttca gatccctgta ctggtgataa atctgctaaa
     1561 taaacatctc ctcgtctaat cattcattcg ttgaattaga agataaatat gattcgttgc
     1621 aatcgcatgc ttcacactct atcggaaaag cttcgttcgc tagggagaga tttaaatcag
     1681 ccatttgtga atatccttct tttaaagatt gttctaagct atgacttcta ttttgactaa
     1741 aagataacat atgagaacct ccaattgatt ccaaaagtta ttaaatgacc tttaattact
     1801 ctaatgataa caaattttat atgcactgac catattattt taacaattca tttgttacaa
     1861 aacgttgatc accatcatga tagattcgcg gcaaacgtct cgacaagtta caaagcactt
     1921 cataattaat agtatgttgc ttctcagctg ccacctctac cgactgtgga ctttctctat
     1981 gattatctat taaaatcacc gaatctccag ctttaacttg atttggcact tttacaattg
     2041 tctgatccat acatacgcga ccaataattt cgcattgatg accatttaca tttacaaagc
     2101 taccttgcat aatgcgtaaa tagccatctg catatccaat aggtaacaat gctattgttg
     2161 ttggatcagt agctgtataa gttgcaccat aacttacaga ctcacccgct tgtagcgtct
     2221 ttgtttgaac tacattagca attaattgca cacttggttt aaggtgtact ttaacttttt
     2281 gctgtacata ctctgatgga taatatccat aaagggaaat tcctggtctt attgcattac
     2341 agaattggca atccattaat agagaacctg ctgagttctg acaatgtata tattcaggtt
     2401 taattgcttc attgaccata tctttaaaac gttgatattg ttcagttgtc atatctcctg
     2461 gttcgtcagc acaggcaaag tgtgtaaaca cgccttcaaa tacaagttgc tcatattgtt
     2521 gaatgatttc aatcacttct tgatacgttt tagtatcttt aatacctaaa cgtcccattc
     2581 ctgtatctaa tttaatatgc aaccataact ttttctcttg ctcaccagaa atgtttttaa
     2641 ttgcttcttt caaccactgt ttagacggaa ccgttaaggc aactcggtgt tgtatcgctt
     2701 tatcaatatc tttagctggt aacacaccta agactaaaat tttagcagta atcccatgca
     2761 ttctaagttc tatcgcttca tctaacgttg ctacagcaaa aaatgtggcg ccattttcca
     2821 ttaaatgacg tgctacttta acactaccta gtccataggc attggcttta acgacagcca
     2881 tcactgtttt atttggatgc aatgtactga atactttgaa atttgatgca acagcgttta
     2941 aatctacatt catatacgca gatctataat atttatccga catattactt cctcctgtaa
     3001 ttcccacacg ttttaaaact aaatcttaat tatcattgta taacaaattt aaaatgctga
     3061 cttttctaaa acaacttggc tcatcgcata atgctcagtg tgtgagatac taacatgtac
     3121 gataaaccct tcgtaatcaa tctttggttt gccaagttcg tcgttgtaac agtctatatc
     3181 gttaaaagct acatgttttc ctaagcctgt gcctaatgct ttactgaacg cttcttttgt
     3241 agcaaacctg ccagctaaaa attcaatttt acgttgctca tgtgtgaaat tgttgaattt
     3301 gtgctgttca ttttttgtta aaatccgctc aaccaatttt ggttgcttac tatataacgc
     3361 ttttattcga tcgatttcga ttaaatctac accaattcca tgtatcattg attattcctc
     3421 atttttattg ttttctaaat gtctctcgtt atttaaccac cgtttcaatc tacgtgcttc
     3481 acttctatct attaattcaa tttcagcttg accacccgct gtaaaaagtg tcaaagttgc
     3541 taatcgatag cgtctcatta taggaccaac atcgatatca atattttgaa tacgaaaata
     3601 tggtattact ttttcatcca aaaataaaat gccgtttcgt acacgcaaat ggtgtttttc
     3661 aaatgcatat ctgcagtgct tatatcgata gactggcgct ataacaagcg tgaaaacagc
     3721 aacaagtaat attataatca cactactaac aatggatata tagttatcta atatctccca
     3781 aaatagccag ttcaaaatat taaatgcgat taaaagtaca agcgctattg gtatccaaaa
     3841 catcacagca cttaacctca tcactttttt agcgtgtggt gacataaaat tataatccct
     3901 catcattttc acctctcaaa taccatgatt tcaatttatt tgcatcttca cttcttgcgt
     3961 attttaagtt aatcgattgg gctcccacac ctttagcaac aataaagcta aaattattta
     4021 aattgttgcg tttaagtaat gtatgttgcc aagtgtcaaa tcctataatg tgatgcgctt
     4081 taaaataata aatatttcgt ttcaatagct cgaaattctg gatagtaatt tgttcttctg
     4141 tcattttaaa acccgcatgt ttgacataaa gatatccttt gatcacaaat aaaccaataa
     4201 tgactattgt tataatcgta aataacaata ataattgatt ccaaaaataa cagccaatac
     4261 ctgccatagc tatgacaata atactaggca ttaaaaagtg tctgtgaaaa cctgaaaaag
     4321 gcataccttc attaacttgt tgataagata aatctggtac taaattctgg ataatttgat
     4381 atgctttgtc tcgtttaata aacggcaata tcgtcacact acctgaatca ttgtcatcat
     4441 cttcgatttt tttattttca aaatcacttg tgatgataaa atgtattgct gtgtagccaa
     4501 atattcttcg tatatatgac tgacgttcaa caacagcttg caatcgtctc gttggtacag
     4561 ttactttctt cttgttaaag agaccatatt caattttaag ttgctcattt tcaagcatca
     4621 ccgaaaagcc ataaaatctt atcatcgtta taatcgttcc aataatatat gccactatta
     4681 atactagtaa aatgatgatt aatactgaaa tacttacaat ttgaacccat tgactaatct
     4741 catgatttag cttcgaccac gggatcaact ctcttacagc gccgtaaatc ggtactaaag
     4801 ctgctaacgt tacaccaatg gcgccactgg tcattgccat aaatagtgat tctttaaaat
     4861 tcatctgata tataggaatg cgtttatttt tctgattaag catactatca gtgttctgca
     4921 cttcatctaa gcgaccttct gcgatatctt ccacattacc ttcaatgtca tgattacagt
     4981 tgtcattctt ctcagcacta gacttttgcg ccccttctgt cttcaactct gtttgcaatt
     5041 gatcaatata tcgttcaaga tattcacctt gttttttcga aataacactt aagacaatac
     5101 catcacttgg tgttttgatt tgtaaatcca caccaccaat aatttgattg acgacccctt
     5161 gtgtcatatc aacggactga atacgtttta tatttaattc tttacgcttt ttattaaaaa
     5221 tacctgttgt taaaatgaaa taattatcct caatccaata acgagtgttc ataattccga
     5281 caatttgaga aatgtatgat attaaaaaga atacaaatac aatacctatc cataaatatg
     5341 attcgggatt cgtataatca aaatccttca attgaaagat aatgaaaata aaaaagacga
     5401 ctatgttttg tttgatagca ttaattatgc cattaaaata tgaaatcgga tgtaattttt
     5461 gaggttcaga catcactttc aacccctctc aaattcgaca tagctctcgc ttcgattatt
     5521 ttaacatcgt catgtgacat catcggtaaa ttaatagtat gacctgcagt cataaatcca
     5581 actttataca aattaagcac tttactaatt ggattagatt taatcgacaa gtattgtaaa
     5641 cgttcaattc gactcgtttc ttctttgtat attaaaaatg atgtacgata ttgtacactt
     5701 agttgatcaa cttgataaaa gcgacaatga tattgccata aaggcttaat aaataatttt
     5761 aatgtactca gagcacctaa aaccaacaaa atataaagta agtaatgtgg ccattcaaat
     5821 cttaaccata taaaataaaa aatgacatac acagctacac tcaatataaa ttctaagcca
     5881 ttcgtaatgt agtaatacaa caatgctgac ttaggactct tagacaactt agtataatct
     5941 gacatgtacc cctctcccca aataaaaaat tatacggatt tataatctat ttcattttat
     6001 ttttatatgt tgataattat agcatatgga atatttcatg ctaatttatt cttcctaaag
     6061 gtacatctaa aaatttagtt aagcagaaag tgcttgaatt gctaaaaaga caccatgtta
     6121 taattttatc aacatgatgc ctttcatcta tattcaatct ttcatattat caagtgcaat
     6181 atttagttca agcacattca cataatcatt tgttaacaca ccacgctgct tacgatgttg
     6241 aatcaagtcg gccactcttg aagtagatat atgacgaaca tcagcaatac gaggtgcttg
     6301 cttcaatgca ttttcaaccg taatatgcgg atctaagccc gacccagaac ttgttgcagc
     6361 atctattgtt acatttgaat taccaaattt aacatgatgt ttcacacgtg ctattaattc
     6421 gttgtttcca ttcgattcat tacttccacc tgatgatacg ccatttttat ataatttttc
     6481 aggattcata ttataatcaa ctgcactcgg tctcccgtaa aaatatcgtc tctctgtcca
     6541 gtgctgtcca atcaattttg atccaactat acgattgtca tacgtaatta aactaccatt
     6601 tgcttgttga taaaaaaata tttgaccaat taacgtgata gctaacggga ataaaaatcc
     6661 acataatact atagttatta tcgttaaaca aatactattt cttatcgtat tcatggtaca
     6721 ggctccttcc tctttacaca aaaaattgta caatcatatc tattaattta atgcctaaaa
     6781 acgggacgat taatccacct aatccataaa tcaacatatt atttataaaa attctatcaa
     6841 tgctgtaccc ctttactttt acacctttca tggcaattgg aattaaggca acaatgatta
     6901 atgcattgaa tatcaaagct gatatgattg cagatttagg tgacgataaa tgcataatat
     6961 ttagtgaagt catttctgga atcgttgaca tcattagtgc aggtaaaatt gcaaagtatt
     7021 ttgctacatc attagctaaa ctaaatgtcg ttaatgcacc tctcgtcatt aataattgtt
     7081 tgcctatttt tacaacctct attaactttg taggattcga atctaaatca attagattgg
     7141 ccgcctcttt agcactaatt gtccctgagt tcatagctaa tcctatattc gcttgtgcta
     7201 gcgcaggtgc atcatttgta ccatctcctg tcatcgcaac aatatggcct ttcgcttgtt
     7261 catctttgat gactttaatt ttatcctcgg gtttacactc tgcaacaaat ctatcaacac
     7321 ccgcttcttt tgcaattgta gctgctgtta aagcattatc acccgtacac ataactgttt
     7381 caatccccat ttttctcaat tcagtaaatc gttctacaag accatcttta atcacatctt
     7441 ttaaataaat cacgccaagc atgacattgt tttcaatgac tattaatggt gtgccacctt
     7501 tactcgatac atccatacag agagactcaa tattaagagg aatattgcct tgttgttgtt
     7561 tgacaagatt tatcatacta ttaggtgcac ctttgaatac cgatatttca tttgtaatga
     7621 ttccgctcat tctagtttca gctgtaaaag gcttatatgt gccatcaatg tctttaggca
     7681 gctcatttat atacatctgc ttcgctaatc gtacaatact ttttccttct ggcgtatcat
     7741 cgtagattga tgacatataa gcagcgacta tcaatttttc cagcatttgt tgattcactg
     7801 gtaaaaattc actagcgatt cgattgccat aagtgattgt ccctgtcttg tctaaaatca
     7861 ttacatcgac atctccacat acttctacag cacgcccact tttcgctaat acattgaatt
     7921 gagtaacacg atccatgcct gcaataccaa tcgccgataa caaaccaccg attgtcgttg
     7981 gtattaaaca tactgttaac gcaatgagca tcgcaatagg taaaattaaa tgcaggtaag
     8041 atgctattgg atataacgtt tcaataacga ctaaaaatat aattgttaac gttgttaata
     8101 atgtaaaaag tgcaatttca tttggtgttt tatttctttc cgccccttca actaaggcaa
     8161 tcattttatc taaaaaagat gtacccgctt cactctcaac acgtatttct aaccaatcag
     8221 atgttacaag tgtaccgcca atgactccat caaaatcgcc acctgattct tttatcacag
     8281 gtgcagactc accagtaatt gcagattcat caacggttgc taatccattt attacaacgc
     8341 catcagcagg gattgtttct ccattttcta cccgaatatt ttgtccggct tttaactctg
     8401 tggcgttcac tatccgatac gcaccatttt cttctatcaa tcgagcagtt aaatttgatt
     8461 gtgcttgtct taaactatca gcttgcgctt ttccacgacc ttcagcaaag gcttctgaaa
     8521 aattagcaaa caatatagtt attaataata tgataaaaat tgtaatcaaa taacctcgcg
     8581 atagatagct agttccaaat atgtcaggaa aacatattaa tatcaacgtt aaaatcattc
     8641 caacctcaac gacaaacatt atcggatttt ttattaattg tttaggattc agcttataaa
     8701 aactcatttt caaagcttct atcaccattg tttgattgaa atatttattt acatgatgca
     8761 ttttttccat ccctttactt tattttaaag ttaaaaattc accaatagga ccaagtaata
     8821 gtactggaat aaatgtcaaa ccacttagta aaacgataaa tacgattagt gatacgccaa
     8881 aataaggttt atcaatcgct attgtatatt tatcttggtg gtatgatttt ttattcacta
     8941 aacttgatgc aatcattaat tgcaaaataa ttggtatata acgagaaagc aacataatga
     9001 ttcctgtaga gatattccag aatgttgtat catctttcag tccttcaaac cctgatccat
     9061 tgttcgctgc agctgacgtc atttcataca taacttgtga gataccatga aaagacggat
     9121 tcgttatact ttcacttgct ccaggaatca taaaagcaag tgctgaaaat actaaactta
     9181 aaattggatg tatgagaaag actaagacaa tacatttcat ttcacgggcg ccaattggca
     9241 tatttaaata ttctggtgtt ttaccaacca tcaaactgca tataaacacc gtcagtaaga
     9301 catatatcaa taaattcatg agtcctacgc cttcgccacc aaatacaaca tttagcatca
     9361 ttaataccat tggtcctaat ccacctagag gcgttaagct atcatgcatg ttattaacag
     9421 aacccgttgt aaatgccgtc gtaataactg taaatagtgc tgacaagcct gctccaaacc
     9481 gtacctcttt accttccata ttcggtccat aaatgcctaa attcgctagt attggattac
     9541 cacgatactc actccacata gttaatgtaa gaattgctat aaaaatgaaa aacattgcaa
     9601 caaataatat cagcgcatga cgatgtactc gtttaccatg tctacttaac atgcgaccaa
     9661 ataagaacaa cattgacata ggaagtaaca tcatactgcc catttctata aaattgctcc
     9721 aaatatttgg attttcaaaa ggtgttgcag aatttcctgc taaaaatcct ccaccattcg
     9781 taccaagatg ttttattgat tcaagtgatg caataggtcc aaatgcaata tgttgaatat
     9841 gtccgcttaa agtcctaatc attaaattag catgcaacgt ttgtggtaca ccttgagtca
     9901 tcagtaaaat actaattaaa catgataatg gtaaaagtac tcggacaata aaccgaacaa
     9961 tatcttgata aaaattacca atgatattag tcaatccagt taaacgtctc aacatcgtta
    10021 tacaaacggc gtaacctgat gcactagatg taaacattaa atatgtcatt acaatcattt
    10081 gcgttaaata tgtcacacct gattcaccgt tatagtgttg taaattacta tttgttaaaa
    10141 aagatattgc tgtattaaac gctaaatcta tcgattggtt taaattatga tttggattta
    10201 aaaaaagcca ttgctgaact attagcaata caaatgatat accccccata aatccattaa
    10261 atgccagaaa atgtttgaca tatgttttag ctgacatgtg ttctaaatct gtgccgataa
    10321 ttttaaaaca catattttca aatctagtaa atattaaatc tactcttgac gattgcacca
    10381 atgctacgcg atataaatat ccactaaaaa catacgtaat cataaccatc attgttagaa
    10441 acaaaattat ttccatgata accctcactt aatatatttc taaaattttt cactacgaat
    10501 taaggcataa aataaataca aaactaatgc aataactacc aataataaaa cgatgagcat
    10561 tgccataacc tccttacaac acaacaacat cgtaacaact tgtttatgag agaaatatta
    10621 attttcaaac ttagttatta agaaatcatt aagatgtgta tgcagaaata aattttatag
    10681 catttaattg tgaagaatat tatgatattg ctatcgaggt gaaggttatg tcaaacactg
    10741 aatcgctaaa cataggaaaa aagcgtggat ctttaacaat ttacatcggt tacagtccag
    10801 gtgttggtaa aacatttgag atgctttcaa atgccattga actatttcaa agtaacgttg
    10861 atattaaaat aggatatatt gaaccgcatc aacgtgatga aacaaatgca ttagctgaac
    10921 aattacctaa aatcgcaacc aattttacta aacatggtag tcatcatttt caatatttag
    10981 atgtcgaccg cataatcaaa gaatcgccga caatagtact tatcgatgag ttagcacata
    11041 cgaacatttc tagagatcgt catgagaaac gatatatgga tattgaagaa attttaaatc
    11101 atggtatcga tgttcatact actttgaaca ttcaacatat cgaaagttta agtagtcaaa
    11161 ttgaactgat gaccggtgta catgttaaag aacgtgtacc cgactatttc ataatgagcg
    11221 ccgatgtatt agaagtcgta gatatctcac ctgaacaatt aattaagcgc ttaaaagctg
    11281 gcaaggtata taaaaaggat aggctagatg tagcatttag taatttcttt acgtataccc
    11341 acctaagcga actgcgtaca ttgacgttaa gaacagttgc cgacttgatg agtgataaag
    11401 aaaaagtccg acacaatcat aaaacgtcac tcaaacctca tattgctgtg gcaattagtg
    11461 ggagcattta taatgaagca gtaattaaag aggcattcca tattgctcaa aaagaacatg
    11521 caaaattcac tgctatttat atagatgtat tcgaaaagaa caggcaatat aaagatagtc
    11581 aaaagcaagt gcatcaacat ctcatgcttg caaaatcttt aggagcaaaa gtgaaagtag
    11641 tttatagcca aaccgttgca ttaggattag acgaatggtg taaaaatcaa gatgtaacca
    11701 aattaattat cggacaacat attagaaata agtggcgaga ctttttcaat acacctttaa
    11761 ttgaccattt aatgtccttt gaacatagct ataaaatcga aatcgttcca atcaaacaaa
    11821 tacctgttga attgaaaatg aacaaatcac cctatcgtcc taaaggcaaa cgtttcgcca
    11881 tagatatgtt aaaaatgatt ttgattcaaa taatttgtgt aatgatggga ctgtggattt
    11941 atcaacttga taagcatgag tctagtacga ttattttaat gatttttctc atcggcatca
    12001 ttttattatc catttggacg cggtcctaca tcattggctt tttagcagca attattaacg
    12061 tatttgtttt taattatttt tttacggaac ctagatatac atttgaagta taccgctttg
    12121 actatcctat tacatttatc gttagcattt taacaagtat tttaacgagt gctttattaa
    12181 aacaaattaa attccaatac tccattacta aaaagcaact ttatcgtaca gatttattat
    12241 ttcaatttaa tgattcgatt aaacaaactt atacagttga aaacttacta ataaatgctg
    12301 gataccaaat taatcaatta ttgcaacaat caattactgt atacgttatc aatcaatcga
    12361 aagtaattaa aacaatacca ttgcaaaacc atatcgataa tacgactcaa cagcatgaac
    12421 aagcattaag ctgggtaatt aaaaatgaaa gacaagctgg tgcaacaaca gatacatttc
    12481 caggcattaa taaatggttg ataccaattg gcacatctcc gattaaaggc attctagcca
    12541 ttgattacca aagttctcaa gtgattaatc catatgatgc atcaatatta gaatcaatgt
    12601 taaatgaact ttctctcgcc gttgaaaatg tgtcgttact taaacaaacg agagaatcca
    12661 tgttacaggc tgaacgtcaa ctgacacatt caaatttttt aagatcaatt tcgcatgaca
    12721 tacgtacacc gttaacaaca attatgggaa atttagatat tttagtatca catagtaaag
    12781 atatgtctat catagaaaaa gaacaattac ttgtgcatag ttttcaagaa agtcagtatt
    12841 tatatctatt agtgacaaat attttatcat taacaaaatt acagtcatca aatgttcaga
    12901 taaaattgca accttatctc gttagtgaat tagtagaaga aatcgatatg attctagaac
    12961 gtcgccattt aaaaaagcgt ataactgtat catcctcagt agatttacag tttatacaca
    13021 ttgacagtaa gttgatttta caagctttat tcaatttgat tgaaaatgca gttaaacaca
    13081 cttctactga caccaaaatc aatttatcta ttcgttatgc tagcgatgaa caaatcgaat
    13141 ttgccgttat agacgaagga cctggaatta gtttagaaga acaacaaaag atattcgagc
    13201 ctttttacac aggatcaaat aaatatttta aagataacca aaaagaaagc atgggactag
    13261 gcttatattt agtacagact atcctacaca aacatcaatc aaacttacaa tataaaccga
    13321 accaaccaca cggcagtata ttctatttca atatagatac agactttaat gaaggagaca
    13381 tataatgcaa tctaaaatat tgataattga agatgatcac gcaatcacac atttacttga
    13441 tgttgcatta actttagatt attacaatgt aactacagcc gacaatgcca cacaagcaca
    13501 ctttaaaatt caaattgata aaccagatgt cattttatta gatttaggtt taccagataa
    13561 agatggatta tgtttgattt cagaaatcag gcaacatact gacattccta tcattgtaat
    13621 aagtgcaaga caagaagaac aaacaattat tcaagcttta gataacggtg cgaatgacta
    13681 tatgactaaa ccttttaatg ttgatgagct tcgggcacga atacgagtca tcgagagaat
    13741 cgctaagtca catcaagaaa ctaacattgt atttactaac ggtttgctaa gcatcgactt
    13801 tggctccaaa tctgttgtta ttaataatca ggaggtacat ttgacaccaa atgaatttag
    13861 cttgttagaa ctattgtcaa atcataaagg aaaagtactc acttatgaga tgatattaaa
    13921 acgaatatat ggctatgtta ataagactga aatgcctagt ttaagagtgc atatgacatc
    13981 attaagacaa aaactttcac aatgtcatga ggacgcaaaa gatattatta aaacacatcc
    14041 acgcattggt tatcaaatgt tgcagtggaa agagaaataa ttaaataaaa aagatcgctg
    14101 ccattaaacg aatgattggc agtgatcttt tttatattca acttattatt tatcgcgcac
    14161 tagtgtcagc aaaatgctct attgtttttt ataagaacat gatactgaaa tttcataaag
    14221 tttatttatg ttcgattatt cttaatttaa aaatagttct ttaaattata tacccaccac
    14281 atttggtgga gaaccatatt taaacagaat gatataaccg cacacagatc tcaatccaat
    14341 caaatattta acctttaaaa cgttagtact ttgatatcta cagagaatca attattgaaa
    14401 acaaaaaaga gctcaagaca ttacatcttt aagctcttaa tctataaatt atttttgatg
    14461 gtcagcaaat gtgcgacctt tcataggtct gcttccaccg ctgctcttct ctttacggtc
    14521 gaattttttt gtacttttct tcttacttga gtatcctttt gaacgtttac tcttactgtc
    14581 aaatttagga ttaccacgct tactatttct gttacgagaa ccgcttggtt taccattacg
    14641 gcctttgcga gataatggtt tttcaaaagt taattgaact tcaacttcat cgttcgcttc
    14701 tactaactct tgtaaaagtg cagcaactaa atcaacatcg ttatattcat ttaacaactc
    14761 tgtagaaatg cgtttcaagc gtgattctga ctctttagac atccagtttt caactttttc
    14821 tttgatgtca tcttcacgtg cttgaagtac ttctttacga tgaggtggac gaagtgcgct
    14881 catttttcta ccattagcat cttcaatttg tctgatataa tccatttcga ttggattaac
    14941 aaacgttaca gcgatacctt ctttaccagc acgacccgta cgaccaatac ggtgtgtata
    15001 gctttcagta tcttgaggta tatcaaagtt ataaacatga ctcacaccag aaatatctag
    15061 tcctcttgct gctacatcag tagcgactaa aatattaatt tggtcatttt taaatttctt
    15121 taatacttct aaacgtttcg cttgtgtaat atcaccatgt aagccttcag ctttatatcc
    15181 tttagaaatc aaagcacttg ttaattcatc aacacgacgt tttgtacgtc cgaatacgat
    15241 tgctaattca ggttgatgaa catctaggaa atttgtaaat gtatcaaatt tctctaattc
    15301 tttaacaatt gtatagaatt cttcgatttg tggatcagac atttcattat tcattgtctt
    15361 aatgattttt ggtgatttca taaattgttg tactaaagct tggattgctt taggcattgt
    15421 agctgagaac aacattgttt gacgttgtac tgctggaatt ttatccataa taaatctcat
    15481 atcatcgatg aatcccatat tcatcatttc atcagcttca tctaaaatca aagtatgaat
    15541 tccgtccgtt tttaatgtgc gacgatttaa atggtcgata acacgcccag gtgttccgac
    15601 tacgatttgt gggccttttt tcaaggcttt aatttggcgt tcgataggca taccaccgaa
    15661 tacagtaaca acttggacac cttgtccacg gctaaattct cttaattgtt cagctacctg
    15721 cattgccaat tctcttgtag gtgctaaaat caacgattga accccttgtt tccctactac
    15781 tttctcaatt aaaggaatac cgaatgctcc tgttttacct gtaccggttt gagcttgccc
    15841 aaggatatca attccttgta acgcataagg gatactgtct ttttggatag gtgtcggctc
    15901 tttaaatccc attgattcaa gtgactgaac cgtattatcc gaaatcccta gttctttaaa
    15961 attttgcaaa ataattctcc tttttacctg tttatttctc aatatacttt tgcatataag
    16021 ttcattaata tttcatcaac ttctatatag taccaccaaa aaaatttaat cgcaataaag
    16081 caatttgcga atatttatta gaatcacatt aattgattgt catatttttg tcaaaaagct
    16141 agcattagat aagatgtaag cgttatgcat cattcgaata atcattataa aaaatttttt
    16201 ataaaatacg tatatcgtta acatttcaca acaaatttta ctgaaacaca tgtgaaatta
    16261 gaccttataa tacaacatct ttttgtaaaa tattatataa acattcaaac tacttcctat
    16321 ataaagtgtg tacatagaat taaccttgat ttagtttcaa atttatagat ttaacataaa
    16381 aagaaaaagg caattttgta tttacacaca aaaccacctc ttctttgtaa tcttttagta
    16441 ttaattcaaa tcattttcta agtaaaaggt cgctcgacta atttctatga aattaaagca
    16501 tttacaactt cttctaactt cataccacgt gagcctttaa ctaatacacg gtcatgcgct
    16561 tttaaatcgc ttgttaaaac ttctatcata tcgtctttag aattgaagtg ttgtgctttt
    16621 tcgacatgtt gctggcccga atcataaata tacttcgctt cattaccaaa cgtatacaac
    16681 acatctatat gcttttcttc taaataatta cctacactga tatgcatttc tttgctattt
    16741 tcacctaatt ctaagacatc tcctaaaatt agaatgcgac gccctgtcaa agtactcagt
    16801 gtatcaatag ctgctctcat acttgtagga cttgcattat aggcatcatt tatcacagtg
    16861 atatcatttt ctaatgtatg ttgctccata cgcataccag ttaagctgac attttttaaa
    16921 ttttgataga ttgtgttata tgtcaaacct aattcatgac caaccgcaat ggcaatcgtc
    16981 gcatttttca tattatgctt tcctaatatt ggcagatcgt aatgttcttt attattaatc
    17041 gtaaatgaaa tacctgtagt atctctatca tcaacagaac aaactaatgc attatcagca
    17101 gcaacaccaa tactaataca ttttacattt tcaacttctt taacatgcgg tttcaataat
    17161 ggttcatcgc catcatatat aaacgtacca ttatctttta gacctattgt aatttcagat
    17221 ttagctttag caatcccctc gcgcgaacct aaatcttgca tatgtgactc accaatatta
    17281 gttataactg caatatctgg ttgagcaagg tttgacagaa attcaatttc atggaaacct
    17341 gacatcccca tctctaatat tgatatttca gtatcattat ctaattccaa aatagttaaa
    17401 ggtaaaccaa tttcattatt gtaattacct tgcgttttct taactttaaa ttcggtatgc
    17461 aatacacttt caatcatatc tttagtcgtt gttttaccat tagaccctgt gacggcaatt
    17521 actttagggt ttacatgtct caagtaagct tgtgccaatt gttgtaatgc cgttaatgtg
    17581 tcttcaaccc atataatagg cccgcttaca ttttcatcta taggtgtccc tctttgataa
    17641 aaagcagccc cagcaccatc ttgtaatgct ttagagacaa agcgatgacc gtcaacattt
    17701 tcacctttaa atggtataaa taacatattt ttagaaattg ctcgtgaatc aattgtgact
    17761 ccatttatct cttgatttaa aaattgatct tcaatttcac aaggaatcca tgattgaatt
    17821 tgctttaatg taacattaat cataataaca acctcagtta gtcaattttg tatttatttt
    17881 tctgtttatc ctggtgacgt tctttagcaa gctcgataag ttttgtaatc aattctgaat
    17941 aagataagcc catattttcc cataattttg gatacatact gaaagccgta aatccaggca
    18001 ttgcatttgt ttcattaata tatatttggt tgtcttctgt tacaaagaaa tcagcacgga
    18061 ctaaaccaga acaatctgtc gctttgaatg cctctaatgc catatttcta agcgttaatt
    18121 gaacatcttc gtctaagtca gctggaattt gtaattgaac cttaccatct ttatattttg
    18181 atttgtaatc gtaaaacgcg acatctttta cgacttcacc tggccatgtc gcttcaggat
    18241 agtcatttcc taaaactgct acttcaattt cacgtgcgtt aacgccttgt tcaataacaa
    18301 gcttacggtc aaattggaat gcttctttaa taccttcttt aagttccgct tcattattac
    18361 atttactgat acctacactt gaccctaagt tagcaggttt aacaaagact gggtaattta
    18421 atttatcatt tactaatttt aaaatgttat gttcatattt ttcatattca gaacgtaaga
    18481 aactaatata aggtaactgt ggtaaccctc gatgttcaaa taattgtttc attacaagtt
    18541 tgtccataga acttgcagct gacaatacac catttcctac atatggtaca tccaaaactt
    18601 caaaaagtcc ttgaatcgtg ccatcttcac cattaggacc atgtaataat gggaatactg
    18661 catcgtatgg ttgtcctgaa ctactttctt tcaatagctg tgaaatctca agcgcctctc
    18721 cattttctaa atgaagctca tcagtagatt taatttcagc tgtaatatta ttttgctttc
    18781 tccaatcacc atcattggta atataaatga tatcaacatg atatttgtct ttatctattg
    18841 catttaatac attttgtgct gtcagaatcg atacttcgtg ttctgcactt ttccctccaa
    18901 aaacgataca aatattttct tttgtcattt cgttttcctc caatgatata tcagggtttg
    18961 ctaccttaat ataaattaat attgatttag tcctattgtt aattgattta ttcgcatctt
    19021 tgaatcttaa tagtatcaca ttttaatact attttgcatt ttaaaaacga ggcgttatgt
    19081 gtctgtatct atgttgattc atttataatc agaacaatat tcccttctat tttattccta
    19141 attcaaattg aaatctatag ctgatatcac tgtgatattc tagctaattt ttaaaaagtc
    19201 atgtaaaatt gatataaaca ttagtgagta taaaaggagt ttgcaatgaa ttattcatct
    19261 cgtcaacagc cggataagca ttggcttcgc aaagtagact gggtattagt agccactata
    19321 gctgttttag caattttcag tgttctgctt attaactcgg caatgggcgg tggtcaatac
    19381 agtgctaatt tcggtatcag acaaattttt tattacattt taggtgcaat ttttgcaggt
    19441 atcatcatgt ttatttcacc taaaaagatt aaacattata catatttatt gtatttctta
    19501 atctgtctat tattaatagg cttgctcgtt attcctgagt cacctattac acctattatc
    19561 aatggtgcca aaagttggta cacgtttggc cctatcagta ttcagccatc tgaattcatg
    19621 aaaattattt taattttagc attagcgcgt gtcgtttcta gacataatca attcacattc
    19681 aataaatcat tccaaagtga tttgttatta tttttcaaaa ttattggtgt ctcgttagta
    19741 ccaagtattt taatattact gcaaaatgac ctaggaacta cattagtatt agctgctatt
    19801 attgcaggtg tgatgttagt aagtggaata acatggcgta tcttagcacc tatctttatt
    19861 acaggtattg ttggtgcaat gacagtcatt ttaggtattc tatatgcacc ttcattaatt
    19921 gaaaatttat taggtgtcca actgtatcaa atgggacgaa tcaattcatg gcttgacccc
    19981 tatacatata gtagtggtga tggctatcat ttaactgaat cacttaaagc tatcggttct
    20041 ggacagttac taggtaaagg atacaatcac ggtgaagttt atatacctga aaatcatact
    20101 gactttatct tttcagtgat tggagaggaa cttggtttta tcggttctgt catattgatc
    20161 ttaatatttt tatttttaat cttccatcta ataagattag ctgcgaaaat tgaagatcaa
    20221 tttaacaaaa tctttatcgt tggtttcgtc actttacttg tgttccatat tttacaaaat
    20281 attggtatga caattcagtt gttaccaatc actggtattc cattaccatt tattagttat
    20341 ggtggtagtg cgctatggag tatgatgact ggaataggta tagtcttatc aatttattat
    20401 catgaaccaa aacgatatgt agatttatac catccaaaaa gtaattaatt taaactattt
    20461 tgagtttcaa atatcataac ttttcaagat gacgttatat agtctattta tgtcgtcgat
    20521 ttaaaatgtc atatatagat attactcgat aataacaatc cctctttgaa gtacacattg
    20581 taaaatgtac actctaaaga gggattttgt tatatagtac ttgctatcat tttagtaaat
    20641 ccagtcaaaa aagctatcat cgaatagtcc gacgatagct ttaacggtgt gtgattcaca
    20701 atcacagtca attattttaa ttcgtgactt actttattag atgctggcaa agtattaata
    20761 atgtctaaac gagatttagt ttttttaata ttcacaccta atgatgacaa tagtttgact
    20821 acattttgaa tcttttcagg acgtttcatt attatcacct cgtttggatc gctttcaata
    20881 ttatcttacc ctattcgaca tacctttact acatcattta caaaattttt aatttatttt
    20941 caaaattaaa atctatagcg cactctacat tataccctaa aatacaattt tgtatccttc
    21001 atcatagatt tctttttcaa tactattcaa atttgctggt gtctcatacg atacagttac
    21061 ttgaccgtct attatattaa tattcacttg atgaacacct atcatatttg aaatgcgttc
    21121 tgtcaattga cttacttgtt cttctgtttc aattcccgct gtgtaaatcg tattttgatg
    21181 tatcatctta aactccttta gtctttaatc aatttttgaa aagtcactaa taactcttcc
    21241 attgcctctt cctgagcacc ttgattaact ttattcataa tacaactttt catatgttgt
    21301 tctaataact ttgtcgcaac actgtttaac gccgaacgtg tcgctcttat ttgcgtaagg
    21361 acatcatcac aatagacatc ttcttcaatc atgcgattaa tcgctctcac ttgtccttca
    21421 attcgattta aacgtgattt aagattcgtt tttatttgtt cagaatgatg tgcaatatct
    21481 tgttcagtca tagcattcac tccttcattt acattcctta ctatactata tcccataaaa
    21541 cacaacgtca acacaaagtg tgtttttcaa actaaattgt catgatattt aaattgcttc
    21601 atgatacaat taataagata tactactcgt ttaagatttt cgatgggagg tttcaaatga
    21661 tagagttatt atccattgca ctcaagcatt ctaatattat tttaaattca atatttattg
    21721 gtgcatttat tttaaactta ttattcgcct ttaccattat tttcatggaa agacgttctg
    21781 ccaattctat ctgggcttgg ttactagtct tagttttctt gcctttattc ggcttcattt
    21841 tatacttact attaggacga caaattcaac gtgaccaaat tttcaaaatt gataaggaag
    21901 ataaaaaagg attagagtta atcgttgatg agcaattagc tgctttaaaa aatgaaaact
    21961 tttcaaattc caattatcaa attgtaaaat ttaaagaaat gattcaaatg ttgttatata
    22021 ataacgcagc atttttaaca acagacaacg atttaaaaat atacacagac ggccaagaaa
    22081 aatttgatga cttaatacaa gacatccgta atgctactga ttatattcat tttcagtact
    22141 atattattca aaatgatgaa ttaggtcgta ccattttaaa tgaacttggt aaaaaagcgg
    22201 aacaaggtgt agaagttaaa attctttatg atgacatggg ttctcgtgga ctgcgtaaaa
    22261 aaggcttacg cccgtttcgc aataaaggcg gacatgctga agcatttttc ccatcaaaat
    22321 tacctttaat taacttgcgt atgaacaatc gaaaccatcg aaaaattgtt gttatagatg
    22381 ggcaaattgg atatgttggt ggttttaatg ttggtgatga gtacttaggt aaatcaaaaa
    22441 aattcggcta ttggcgagat acgcatttac gaattgtcgg ggatgcagta aatgcattgc
    22501 aattacgatt tattctagat tggaattcac aagccacacg tgaccacatc tcctatgatg
    22561 atcgttattt cccagatgta aattctggtg gaacaattgg cgttcaaata gcttctagtg
    22621 gtcctgacga agaatgggaa cagattaaat acggttattt gaaaatgatt tcatctgcta
    22681 aaaaatcgat ttatattcaa tctccctatt tcatacctga tcaagccttt ttagattcta
    22741 ttaaaattgc ggcattaggt ggtgttgatg tcaatatcat gattcctaat aaacctgacc
    22801 atccgtttgt tttttgggct actttaaaaa atgcagcatc cttattagat gccggtgtta
    22861 aagtatttca ctacgacaat ggctttttac actcaaaaac acttgttata gatgatgaaa
    22921 ttgcaagtgt tggaacagct aatatggacc atcgcagttt cacattgaat ttcgaagtca
    22981 acgcctttat ttatgaccaa caaattgcca aaaaattaaa acaagctttt atagatgatt
    23041 tagcagtatc ttctgaatta acaaaagaac gttatgctaa gcgaagtctt tggattaaat
    23101 ttaaagaagg tatttcacaa ttattgtcac ctatcttata aaatagaaat atggggagtg
    23161 taactttaat gcaacaatca gacatcatta gtgcagccaa aaaatatatg gaatctattc
    23221 atcaaaatga ttatacaggc catgatattg cgcatgtata tcgtgtcact gctttagcta
    23281 aatcaatcgc tgaaaatgaa ggtgttaatg atactttagt cattgaactc gcatgtttgc
    23341 ttcatgatac cgttgacgaa aaagttgtag atgctaacaa acaatatgtt gaattgaagt
    23401 catttttatc ttctttatca ctatcaaccg aagatcaaga gcacatttta tttattatta
    23461 ataatatgag ctatcgcaat ggtaaaaacg atcatgtcac tttatcttta gaaggtcaaa
    23521 ttgtcaggga tgcagatcgt cttgatgcta taggcgctat aggtgttgca cgaacatttc
    23581 aatttgcagg acactttggt gaacctatgt ggacagaaca tatgtcacta gataagatta
    23641 atgatgattt agttgaacag ttgccaccat ctgcaattaa acatttcttt gaaaaattac
    23701 ttaagttaga atctttaatg catacagata cggcgaagat gattgctaaa gaacgtcaag
    23761 actttatgat gatgtacttg aaacagtttt ttacggaatg gaattatcac gactagacat
    23821 tggagttgta gtatgatgat gcgatgtaat ggcgtattgt tgtgggagct tggtgttgat
    23881 gccatgccgt tacgattcta tgatatgttg ttgggacgtt gcaatgtgta ttatgccgtt
    23941 gtgacgttat tatttcacac tgttacatgc attagtgaat tgctgtggac atgttgcgtt
    24001 acgacatata cttctacact gatgaatcat tgtgtcaaga tgacattgcg atgaagaatg
    24061 acaactctgt tattaaccac tttttacata ctgaaatctc gttaatatta tttcaaataa
    24121 aaacagcagt aggatgactt tcacatttga aatcatctta ctgctgtttc tatttatgac
    24181 atattgtata atgtgacact aagtttcgct attgaagcga aaaataatgt gcgccctata
    24241 aagttaaaat tatcttcaac ttttagggtg cacattattt ggacttgcta aggttatttc
    24301 tttttctttt tagacactac ttgtgtgttt ttgccttttt tattgctgcc gccgttgtgc
    24361 tctctttcat acgcttcaat gaaaggttgt acttcttttt tagcgacttt ttcataataa
    24421 atgttcgcaa agtgtgtttg aactacaagg aacgccgcac tgactgacca gtacaaacca
    24481 agtgctgatg ctgagcttaa tgaaatccag ataatcataa ttggtgaaat gaccatcatc
    24541 atgtaaccca tttgacgttg ttcgtctggc atcgttttac ttgatacata tgcttggata
    24601 aagtataaaa caccggcaat aattgtaatc caaatatcag gacgtcctaa atcgaaccat
    24661 aagaagtgtg gatatttaaa caaaccatct acaagttggt ctttaagtac aaagtataat
    24721 cccatgatga ttggcaattg gattagcatt ggtaaacaac ccaacatact cttaatcggg
    24781 ttcatgtcat actttttata tacttgcatt aattcttggt ttgcagccat tttttcttct
    24841 tgtgtacgcg cacgtttcac tttttcttga attttttcaa cttctggctt tgcaactttc
    24901 attttttgac gcatcatatg actattttta tagtttgaca acatgaatgg taataaaata
    24961 atacgaatta ccaatacaag gataataata gctaaaccat aattgtcgtt taataagtta
    25021 tttcccaacc aatccaatac atttttcatt ggatctacga atgtattgta gaaaaaccca
    25081 ctacgttttt caggtttaga atagtcacaa ccagccaaaa agaccataat acctaaaaat
    25141 aatggtagta acgctttttt cttcattttt ccacctctat cattatattc acataggatt
    25201 tattctatca cattaatgag tacgtatgaa acaataagtg gaaaaattta actaattatt
    25261 aaaaaaatct ttgaatcgat taacagtctt ttcaatattt tcacttttag aaatggctga
    25321 aatgactgaa attccattgg cacctgcttc tacaatcggc gccacattat tagtattgat
    25381 accgccaata gctacaatcg gtagttgcgg attcatttct ttaaacgttg caatcatttc
    25441 tggacctact ggtatatgcg cgtcatgctt cgacggcgta ggatagattg gtccaacacc
    25501 tatataatca acatgagtta aatcagattt tgcatactca tctaaatcac taatactaag
    25561 tccaataatt ttatcagtga aatattgtgc tatctctttg actttcgcat catcttgacc
    25621 gacatgtata ccatccgcgt taatttcttt tgccaaggat acatcatcat taacgataaa
    25681 aggcacatca tattgatgac agagatgctg taattcttta gctaatacaa gtttatcgtt
    25741 tccttttaaa gctgattcac ccttttctcg aaattggaaa agtgtaatcc ctgcctttaa
    25801 tgctgcttct aatacttcat gaatagttcg atgactcgga acatcggagg tcccacaaat
    25861 aaaatacaca tttagatacg attggttaaa catattattc cacctcttga atacgaatcc
    25921 gttgttgata ggttgtttca tttaaatgat ataacgtatc aagcaacaat ggtgaaaacg
    25981 taccaggacc accacaattt tcattttcag cagctacctc agcagcaata ttaaatacgc
    26041 ttaccgcttc aattaacgct tctatgtctg gttctgtttc tctaaataaa aatccagcaa
    26101 taacgcctcc taataaacaa ccagctccag ttactcgtgc taataatgga gatccattag
    26161 ctaatacgat ggctttatta tcttgaacaa taacgtcctc tttacctgtg attactattg
    26221 cagttttata tgttgcgtaa gcctttttcg ctattgtaac cgcatcaaga ttagcatcac
    26281 tatctgtacc tttcatagtt gctgtatcat caatcaacgc taatatttca gatgcattgc
    26341 ctttaattac tgatactttc gctgatttca ataataattt acaaaattgc tttcgatatg
    26401 tagaagcacc aacagctaca gggtcaaata caataggtaa gcctgcctca tttgccgttt
    26461 gagcaatcgc aataatatct tgttcatttt ctgctgttaa agtaccgata ttgattaata
    26521 gcgcttgtgc aactttgtaa aattcttcag cttcttcggg agcttcactc attgcagggc
    26581 tagcaccaat acttaataaa ccattcgctg taaaattttt aactacatcg tttgtataac
    26641 aaattgttaa tgggttttca atacgtattt tatttagata attcatcgtc taatccctct
    26701 ttctttaaat atgcaaaatg attcactgga cctctaccac ggccgatttc aggcgtatat
    26761 tgtatactca ttgaaataaa ctttttagcc ttgtgtacag cctcaaataa tggtctacct
    26821 tttgcaagtt ctgccgttat aactgctgaa aatgtacacc ctgttccatg cgtatgtttt
    26881 gttttaaatc gttcattttc aaatgtttga acaccttcgt tagtaaataa ataatctttt
    26941 gctatatcag tatcatttga atgaccgcct ttaatgatga cacctttact accaatctca
    27001 ttaataaaga tgcggccagc ctgcataatt ttttcttcac tatcaatggt tagtcccgtt
    27061 atttcttcag cttctggtaa attcggtgtt actacgtcag ctaatggcaa taacgtatgc
    27121 tgcaagtttt gctttgtgtc attatccatt aatgaatcac cgcttttcgc caacataaca
    27181 ggatcaatta catatggaat agattcatgt tgcattaaat aatgacgaat cgtttccata
    27241 gtatctgctg tagcaatcat ccccgtttta atagcatgcg gtaaggtatc gttgaagaca
    27301 ctatcaagtt gttcatctac ccattgatga tttaaattat gaatatgttg tacgcccaat
    27361 gtattttgag caacaatact tgtaacgacg cccataccat atacaccaca tgaatgaaat
    27421 gattttaaat cagccattac gccggcacca cctgttggat cagtacctgc aatggttaat
    27481 gctattttag gtttaatcat ttacttttcc tccaaattcc cattgttcta gtgtcatagc
    27541 catattgaaa aatcgacgct catgtatgca actttctaaa aatacttgct ttacttgttc
    27601 caattccttg tcagacattg attcggctaa tttattcatt aatgcctcaa atacgttaat
    27661 tatgtcatcc atttcagtac tataaaaatc aaaccatttt gccgtatctt tttctctatt
    27721 aagcttatga tcactttgag agcgcttagc taattctgca taaatatatg gacaaggtgc
    27781 cattgcagca attgtataaa tagcattttc acgactatgc gcttggaaat acatatgttt
    27841 tctgtaatgg tcgccacttg gaggccaaac ttttgtttta atgatttctt cgtatgattc
    27901 accaacaatt tgcgctaaaa tatcatgcgc aagtacttca ccttcaacca taaactctat
    27961 ttgctctact aaaaatttta cgtcattcat gctattcatt tttggaatta acaaagcata
    28021 taagtttgtg aattctttta aataagctgc atcagcttgt aaatagtgac gtaatgcatc
    28081 agcttgtata ttgcctaata acattttttg aataaagtca tcctcataaa tatcattaat
    28141 gattggcttt gcagcttggt acaatttttg tgaaaattcc attgtaaaaa atcctcccta
    28201 aataaaaaaa ctacttccaa catgaaagta gtttgatggc aatgttgcta tactagcccc
    28261 atcacttcaa taactacttt cctacgttgg tactaaccaa atcaggtcat aagggtctga
    28321 acaattcatc tcagccatat cattaggctc ccctagtagt tccttagtat tcaattgcaa
    28381 attaatctta gcaaacggtt tcaacatttt caattattgt tgctcagttg tattattatc
    28441 tttaaataat aattctataa tgacatatat ttgcgaaata aaaaagaccg gaacatatcg
    28501 agaattcccc gatatattcc aatctaaaag ttacttatat aactattgat tagctatgca
    28561 taaatggctt atgcagtaac ccaatgtcca gcgccaccag tgttatataa ttttactgct
    28621 gcggcatctt gaacactttc aggagcattt gctggtgata cacctttata tttagcaggt
    28681 gctactgaat cccaagttga ttgtaagaat tgatacttac cagctgcacc tgatgttgga
    28741 tttacagcat gaatattgcc acctgattca cgttgagcaa tttgttttag atgatcattc
    28801 acatttactg atgaaccttc tgatgctttt gattcagttg gtgttgcagt aacttgtgaa
    28861 ttgtttgatg ttgatgcttg tggttgttga gtttgagcat tttgtggtgc ttcaacttct
    28921 tgtgattgta cttgattagc ttgaacagct gatggtgcaa cattattagt tgcaggtgct
    28981 tgtgcactca tgtctgctcc attagcacct gttgcatggt aattccaagc aaagtgtgta
    29041 ccatctgatt caaagtgata agtaaaccct tcatagtcaa atgtataatt ataagcgcca
    29101 gcttcaattg gtttttgatt taatgtttga tcatttgatt gcgccatttg cgctaaagat
    29161 gctttattta agtccgcttc acttgcatgg gcttcgtgac ctgcatttcc tgctacgatt
    29221 cctaaaccta ctgctaatga tgatgcgagt aatgttttct tcataatctt aaaatcctcc
    29281 tacaagtaat ttgtttctct aaaagtttta cagagattac tgtaacatct gtaaaatccg
    29341 tgcaggttac aacaaaataa aaaaatagcc ttgtttttta cacagtgatt acaacgaaat
    29401 cccccacaat ttcaaatatg attctatcga gaattgtcat gacagtaaaa atgtttttca
    29461 tttgcaattt tttatgtaat cgttttgcaa tctaagtcta ttttctatta gaaaaactac
    29521 acaaaaagac gacctacaca acagtactag tcatgtaagt cgtttttaag tgagtatatt
    29581 tcaagttaat tagatctata aaaaatttag gatggattaa atgtatatta aggatgttta
    29641 ggataattgg atttaaattt ctaataagtc atgattatct atattttgag agtcaatatc
    29701 taaaatacta tctgagagaa tttcattatt ttgggattta ggggacataa attttattgt
    29761 ttcaacatat aattcagtga caaagtgtgt ttgtccgtct ttatcatact ttcttgatct
    29821 catttgacca gttataccaa ccaatgtacc ttgattagta tatttttcta tattagaagc
    29881 taacttgcca aatgctttac agaataagta atcacagacg atttctccat tttcatcttt
    29941 ataatttcgg tgcgttgcaa cacaaaacgt tgcaattttt ctatcctcct tttcaaatat
    30001 ttgtgcgtct ttcgtcagtc tcccgacaat tacgatttta tttagcatgt agtgtgtgat
    30061 tcacctccta tgcctatatc ttaattacta gcttaaaaat ggtcaaaatg gcaaatttta
    30121 tataattaat agctatagca tctcgttatt tgttatattt aaagaaatta gtcatgaaat
    30181 gaccttaaat cttctaaata attcaaaaat cataaatatt aaactaatgg gatgtgggaa
    30241 tatgaaaact tttaaagcag taaggtttca aattgtgaat gaacacggca gaattataga
    30301 atatgaatta gaagatggcg taataattaa taaagaggaa agtggcacgg gttggttgct
    30361 tgaaattgtc atttctaatg agcattatga aacatttaag gaatatcaag acagtgaaca
    30421 gttattggat attcgtgtcg tcatcacgcg tccagccaat gatccagctt tatttgaatc
    30481 tactgtgaaa agtattaaaa attttaaaac aacaatgtct atcgtatttg aatgtcatat
    30541 ttacacttta cgtcaacagt atgctgaaag tttattagaa caacttattg atgatggatt
    30601 atctggtgaa gaattaaaaa aatcatttaa tcgaatgatg cagtctaaac caaagttaaa
    30661 ggatgaaaaa ttagaagagt aaaataaaaa acattcaaag attatgccaa cacattaaat
    30721 ctttgaatgt ttttttgttt tattttacat cttgaattgc aaatgtaagt tcacaactac
    30781 aagcaagttg accatcgaca gtagctttag cattaccttt accgattggt cctttaattt
    30841 tagtgatttc tacttccaac gttaaagtat caccaggtac tacttgacgt ttaaaacgac
    30901 atttatcaat accagcaaat aaagcgattt tacctttatt ttcttcacta tttaaaatag
    30961 ctaccgcacc tgtttgagct aacgcttcag taattaatac gcctggcatt accgcatact
    31021 caggaaaatg cccttgaaag aatggttcgt ttcctgatac ttgtttaata gccacacaac
    31081 gttgaccttc ttcatattca actactttat caattaataa aaatggctgt ctgtgaggta
    31141 taatttgttt aatttggtta taatcaaaaa ttgtttccat ggttgaaatc ctccattata
    31201 ttaatttact gaattaatcg ttaatacgtt caatgtctgc acctaattgc ttcaatttac
    31261 cgtgtaagtc aacatagcct ctatctaggt gcgttaattc agtaacgctt gttttaccat
    31321 cagcaactaa tccagctaaa attaaggctg ctgctgctct taaatcagtc gctttaactt
    31381 gtgcaccttg caattgactt ttaccttcaa gtttagcact acgaccttct acattgatat
    31441 tagcattcat acgtttgaac tctgcaacat gcataaaacg gttttcaaaa acagtttcgg
    31501 ttacgacttt atgaccattt gccgttaata acaatgccat catttgtgat tgcatatcag
    31561 tcgggaatcc aggatgtggt agtgttttga tgtctacagg ttgtaattcc ccttcagcac
    31621 gtacacgaat accatcttct tgatagtcca attcaacgcc catttcttct agtttataga
    31681 ctaaactcgc catatgttct ttgattgcac cacgtacaaa aatatcacca cgtgttatag
    31741 caccagcgat tagtaatgtg cctgcttcaa ttctatctgg aatgatagca tgttctacac
    31801 catgtaatga ttctacacca ttgattgtaa ttgtgtctgt accagcacca gtaattctac
    31861 cacccatttc attaatgtag tttgctaaat cgacaatttc aggttcttta gctgcatttt
    31921 caattaaagt cttaccctta gctaatgatg ctgccataat aatattttgt gttgctccta
    31981 cacttggaaa atctaaatga attgatgtac cttttaatcc atctttagca ttagcataaa
    32041 tattaccatt ttcaagatga atttctgcgc ctaaagcttc aaaaccttta atgtgttgct
    32101 caatcggtct acttccaatt gcacaaccac caggcaatgc aacaatagca tgtcctagtc
    32161 ttgctaaaag aggtcccata actaaaatac ttgcacgcat tttactaaca tattcatatg
    32221 gtgcctcttc atttagagtc tttgttgcat caacgacaac agcattttcg tcctttttgt
    32281 atgtaacgtc agcatttaaa gttgttaata cattatttat tgtttctaca tcacttaaag
    32341 ctggaacatt aactaattta ctcggtttat cagaagctaa taaagatgct gtcaatattg
    32401 gtaatactgc atttttagca ccttctactt taacttcacc cgttaattta tttccacctt
    32461 tgattactat tttatccatc gtaaatcctc cacttagaac tcctattact ttacatttcc
    32521 ctattttaaa attattttaa gtcattattt aattatatct agttttgatt acaaatcata
    32581 gagttagact tattttatta aatattttac ctgcgtcgag tattgtaaca aatctacaat
    32641 aaaattgctt actgcagtgc ctaataaaat agcaacaaat atcatacaca cttgtaattg
    32701 agtggcgtat ccctttttaa aaaattgatc taatctaatt gattgtaaag cccaataggc
    32761 aatacaaata catacaacat gtaacactaa atggataact gcatattgtc cgatataatc
    32821 cattttatca cctcataaga ttactgtatt acattgtaca tgaaaaattt aaataatgat
    32881 acaaagttta atacccgttt ttagtaaagt ttaagctaac ttactatata attcttttta
    32941 cataaatatc ataactataa agtatcttgg catgaaaaaa tgtagctact ttcaaaaaat
    33001 gaaatgtcga ctgtagatag tggtgaagga aattttgatt ttagcaatct agtagtgatt
    33061 gtaaaaagta aaactatttt tgggagtcgg acataaatca acgtctagac tctatagtgt
    33121 tatatttggc agtagtttgc ggggccccaa cacagaagct ggcggaaagt cagcttacat
    33181 taatgtgcaa gttgggggtg gggccccaac ataaagaaat tggaacacca atttatacag
    33241 acaatgcaag ttggggtggg ccccaacata aagaaatact ttttctttag aaattagtat
    33301 ttcttataca tgagttttac tcatgtattc ctatttttaa atacacatta gctgtgttta
    33361 atgataaaga accactacat cataaatctt taatggttct ttatcaattc cttccccctc
    33421 tcatgttttg tatctttaaa tcaatataat tcaaaaaagg gtcgaagata tgaaatcaca
    33481 tcttcgaccc tttatttact attttaattc agccacacgc aaacggttat ttgctctctc
    33541 taaagctctt tcggctctat gaatatcagt attgtcgtca tcattttcca agtgagactc
    33601 tgctcttgct ttggctaatt tagctctttc aacatcaatt tctcttgcag tttctgcagt
    33661 ctgaacaatg attgaaactt tatcttttct aacttcaaca aagccatcgc ttacagcaat
    33721 atattcagtt ccatcgtgaa atttcacttt tacaaagcct gtttttaaag cagctacagt
    33781 tggaatatgt ccactcatga cacctatctc accagctgtt gtttgcataa caacgagttc
    33841 aacattatca cgattgtaaa cagaaccatt aggagtgaca atatctaggt ttaatgtatt
    33901 cattatccat tcctcctaat tgttatactt caacacccat atctttagct tttgcaataa
    33961 catcatccat gctaccaact aaacggaaag catcttctgg aatatggtca tatttaccat
    34021 ctaagatatc tttaaagttt gcaactgttg tcttaacagg tacataagaa cctttttgac
    34081 cagtaaattg ttccgctacg tggaagtttt gagataagaa gaattgaatt ctacgtgcgc
    34141 gttcaactgt ttgtttatct tcatcagata attcgtccat acctaagata gcaatgatat
    34201 cttgtaattc acggtatttt tgaagtgttg attgtacatc acgagctact tcataatgtt
    34261 cttgacctac aattgatggt tccaatgctc ttgatgtaga cgctaatgga tccacggctg
    34321 gataaatacc catttcagtt aatttacgtt ctaagtttgt agttgcatct aaatgggcaa
    34381 acgctgtcgc tggagctggg tcagtatagt catcggcagg tacgaatacc gcttgaatag
    34441 aagtaactga tccttttgtt gtagacgtaa tacgttcttg taattgtccc atttcagtag
    34501 caagtgttgg ttggtaacct actgcagaag gcatacgacc taataatgca gatacctcag
    34561 aaccagcttg tgtaaatctg aaaatgttat cgatgaataa taatacgtct tgaccttgtt
    34621 cgtcacggaa atattcagcc attgttaaac cagataatgc aacacgcata cgtgcaccag
    34681 gtggctcatt catttgcccg aataccatgg ctgttttctt aattacacca ctgtcactca
    34741 tttcgaagta taaatcgtta ccttcacgag tacgttcacc tacaccggcg aatacagaaa
    34801 taccaccgtg ctcttgagcg atgttgttaa ttaattcttg gattaatact gttttaccta
    34861 caccggcacc accgaacaat ccgattttac cacctttaat ataaggtgct agtaaatcta
    34921 ctactttaat acctgtttct aaaatttgaa cttctgttga aagttcatcg aatgctggtg
    34981 cttgacgatg gataggatcg cggcgaacag aatcactaat ttcttcttta aggtcaattg
    35041 tttcacctag tacattaaat acacgaccta atgtttcgtc accaacaggt acactaattt
    35101 ctttgcctgt atcttttaca tccatgcctc tttggacacc atcagttgaa tccatcgcaa
    35161 ttgtacgaac aacgtcgtca cctaattgca gcgcaacttc taatgttagt tgtattgtac
    35221 cttcttcttt aggcacatca ataaccaagg cgttattaat tttaggaact tcgttatgtt
    35281 caaatcgaac atcaattaca ggacccataa cttgagttac acggccaatt cccatgctat
    35341 tttcctcctt taaatattat tcaagcgctg cggaaccacc aacaatttca gtaatttgtt
    35401 gcgtaatttc agcttgtctc gctctgttat attctaatga taagtcatca ataagttcag
    35461 ttgcattatc agtggcattt ttcatcgcag tcatacgtgt tgcatgctca cttgcttttg
    35521 cgtctaatat tgttccgtaa atcaaactct caacatattg aggcaagatt acacttaaga
    35581 tagattcttt atctggctca aattcataag aagacaaatg accatgtccc ttactagaat
    35641 cctcttgaga taatggtaat acttgtctag atgtaggctt gttttcaaga acgctgacat
    35701 aatgactata gtatatattt aattcatcaa tttcttcttc actgtataag tctatagcat
    35761 ggttagctag tgcttgaaca gatttgaaag aaggttgatc aggtacgtct acttgagaat
    35821 actcaatgtc ataacctcta ttttttagga aatcaacacc ttgttgccct aaaactacaa
    35881 tactgtattc gctactatct tgatgtttcg cttcaatatc agtaatcaat tttttaagca
    35941 cgtttgcact atatgcacct gctaaacctt tatcactcgt gataactaaa tatccacttc
    36001 tagtaatttt acgaggtctt agcattggat ggtttgtatt gctacttgcc cctgcaactg
    36061 cagtaattgc atcttgcatt ttatccatat atggtgtgaa ttgttttgta tttttttcag
    36121 ctctacgaag ttttgaactt gataccatgt tcatcgcttt cgtaatctgc ttcatttttt
    36181 tggttgattt tattcgagta tctatttctt taagagaagc cactatctca ccaccttata
    36241 ctaaacttgt ttattattca gatttgctaa agcttttttt gaattcgtta attgctgtgt
    36301 caaacttctc agcatctggt aagccaccag tttctctgat ttcatttaac agttcagtag
    36361 catttgattc tgcccagtgg tttaactcgt cttcaaaacg tgtgatatct acaactggaa
    36421 tatcatctaa atatcctttt gttaatgcat aaataatcaa cacttgatgt tcaactggta
    36481 atggtttgtt ttgatcttgt tttaagactt caacagtacg tttaccacgt tctaatttac
    36541 ttgcagtaaa ttcatcaagg tctgaaccga attgtgcaaa tgattcaagt tctctgtatg
    36601 acgctaagtc aagacgtaac gtaccagcaa ctttcttcat tgctttaatt tgtgcagatc
    36661 caccaacacg agatacagat tgtccggcat taatcgctgg tcttacacct gagaagaata
    36721 aatcagattg taagaagatt tgtccatctg taattgaaat aacgtttgtt ggtacataag
    36781 ctgaaatatc accagcttgt gtttcgataa ttggtaatgc agtaattgaa ccgccaccta
    36841 agtcatcgtt taattttgct gctctttcta ataatctact atgtaagtag aatacgtcac
    36901 ctgggtatgc ttcacgacct ggaggtctac gtaataataa tgataactca cgataagctg
    36961 ctgcttgttt agttaaatca tcataaacga ttaaaacatg tttaccgtta aacatgaatt
    37021 cttcacccat tgttacacct gaatatggtg caatatataa taatggagaa ggttcagaag
    37081 ctgatgctgc tacaacaata gtgtagtcta aagcgcctgc ttgtcttaac ttttcaacat
    37141 ttgctcttac tgttgaatct ttttgaccaa tagcaacata gatacaaatc gtaccttgat
    37201 ctttttggtt caaaattgtg tcaattgcaa ttgttgtttt acctgtttga cggtcaccga
    37261 tgattaactc acgttgacct ctaccaattg gtactaaagc atcaattgct ttgatacctg
    37321 tttgtaatgg ctcatctact gatttacgat ccattacacc agtagctttt ttctctactg
    37381 gacgtgtttt agttgtgtta atcggtcctt gtccatcaat aggttgtcct aatggattaa
    37441 caactcttcc gattagttct tcacctactg gtacttccat gatacgacca gtacgtttaa
    37501 cttcgtcacc ttcagtaata cctgtatatg gtcctaaaat aaccacaccc acgtttgact
    37561 cttcaaggtt ttgggctaaa ccaagtacgc cgttatggaa ttctactagc tcaccagcca
    37621 taacgtcatt taatccgtga attaatgcaa taccatcacc aatttgtaat acagtaccta
    37681 catcagttac ggacatttct gactcataat tttcaatttg tgagcgaagt aatgcactga
    37741 tttcttcagc ttttatggcc atctatgtca ctcctcttta taattaatta actcttctaa
    37801 attttctttg taattggaca agatcatttc taacactacc atctaataca gttgtgccga
    37861 ctttaactct aaatccacca attaaatctg gattaatttt tgtatctaca ataactttag
    37921 ataacttcgt ttgttgagtt actagtttga caatcttatc taactcttct tgactcaatt
    37981 catatgttga ctcaattgtt gcaaaatctt gattgtagtg tccgttatat aagctttgga
    38041 acgccttgaa tacgtcagct attaatgaga tatgtctatt atctgctaaa acgtacatca
    38101 tatttttaat gtatggatta atgtcagtaa atacaccatt aatcaactca cgacgttgtt
    38161 ctgctgtttg agttggatta ctgtcaacca ttttcaattg ctcaatttta tcttttactg
    38221 cttcatttat aactgttaat tcttgattaa tagtttctaa attatttgta tctaatgaca
    38281 cgtcaaataa tgctttagca tacttgttag ctacttttac cattatttat cgcctgcctc
    38341 ttttagatac ttgtcaacca atgctttttg gtcttgttca gaaatttctt ttctaagaac
    38401 tttagaagca attaacactg atagttcaga tacttgatta ttaatatctg caatggcacg
    38461 ttctttttgg ctattgattt cactttgtgc tgtttcaatc ataccgtttg cacgtacgtt
    38521 tgcttcatga ataatttgtt cttgctgttg acgtgcttga accttagcat cttctaaaat
    38581 cttttgaact tcttcttgtg tttctttaag tttttgttta ttttcttctt caagtttctg
    38641 tgcatttaac ttagcttgtt ctgcgtcatc gatatctctg ttaatatctc tttcacgttt
    38701 atccattaca tctttcaatg gaccccatgc gaacttttta agtaacgcaa gtaacacgat
    38761 gaaagttagg acctgtacaa tcacagtacc ccactcaacg cctccagctg caccaagaac
    38821 gaataagtta gctgtttcag tcacgggttc atgacactcc tttcattaaa ataatcgcta
    38881 gtgttatata gaaaaaaacg acgaggttag gacctactga atttatgcga taggcatggt
    38941 gcgttcatat ctcaactatt taataaagtt caaagatatt actatatatg cgtcatgaat
    39001 tatgtcctat gcgctttgtc ccgacctctt ttatctgtta attatccagc aaatgtcatg
    39061 aatgcaatta ctacaccgat gataggtaat gcctcaacta aacctacacc aatgaacatg
    39121 atacccatta attgaccacg tgcttctggt tgacgtgcta caccttcaac tgttcttgaa
    39181 acgattaaac cgttaccgat acctgctcct aatgctgata aaccaattgc gattgctgct
    39241 gcgattaaat tcataattta atttcctcct gtgattgtat ataattattg aaatttttta
    39301 gtgttcatct gccactttat gtgacatata aaccatcgaa agcataataa agatatatgc
    39361 ttggattgtt cctacaaata ttgaaaatgc ttgccaaaca attaatcctg ggatacttat
    39421 aatccaaccc catgctggtt cgttaaagaa taagccagca agtaatgtta atagtatctc
    39481 acctgcaaat atgttaccgt acaaacgcag accaagcgtt aatgttgaag tgaactcttc
    39541 aaaaacatta ataattgcca atggccaaaa cggctgtaca taacctttaa gatattgttt
    39601 cgtaccacgc attttaattc cataaaagtg agttaacagt attatcgttg tagacaacgt
    39661 taaagtcact gttgcatcag ctgttggtga tttccaccac aatgtgtgat ctttcgttac
    39721 tatagaaaac ggaagaccta acatattagc tataaaaatg tacagaatca gcgttactgc
    39781 taagaagtgg aattgaccac cttttttcca agccatgtta ccttcaatga ttcccctcac
    39841 gaaatcaaaa atccattcaa cgaaattttg tttgccagtt ggtctttttt tcaaattacg
    39901 cgtacaaatg atagcaagta gaaaaacaag aaacgccgta acaagtatca tcaatatact
    39961 tgataaattg aaaacgatat caaaaccgaa taaattccaa ctcacgagcg gggatttgtg
    40021 atccataatc tcacctcttt cttaatttat ttgctcacct ttagtaaagg atgtatgata
    40081 actacaacat atgaaatcat taaaccaata attataccga ttatacttac atgcgattta
    40141 ttaaagtacc aaatcataca ggcaataatt gcaactaagt atcgccacat atttccagtt
    40201 gaaatatgca tagtgtctgg tcttttagct ttggctaagt agctctcaaa tataacagta
    40261 ttgattgcag aaccagtaac accaatgatt aatcctaaga taaatgcatg gtgtgtaaaa
    40321 aggtataatc ctcccaatat tattaataaa tacaaataat attgaatgaa ctgtttaaaa
    40381 atgttgtaga aacgactcat tttatatgcc tccgtgtgac tgatatcaat catgaaaacc
    40441 gttccactca tacaaactaa atgataatat aggcgatttg tggtgtcaat tctattcaaa
    40501 ttgttgtaaa aaaataagca tgttcagaca caatttagac acaattagac aaaaagtcta
    40561 tttttcttag aaatcgcttg gtttttcagt gattaaattc aaataatact taatatgatt
    40621 aactattctt tctgaagcaa atccatcacc gtaaggatta gatgcttcag acatttgatg
    40681 atataatctc tcatcatcga ttaattcttt tgcagcttga tacacatttt gcttatttgt
    40741 tccaatgact tttaatgtgc cagcttcaac accttcagga cgttctgtaa cgcttcgcaa
    40801 aactaaaact ggcttattaa atgatggcgc ttcttcctga attccacctg aatctgtcaa
    40861 aataaaataa gattttttag caaaattatg gaaatctact acatccaaag gttcaatcaa
    40921 ttcaattctg tcatgactac ctaaaatctt ttgagccacc tctcgaactt tcgggttttt
    40981 atgcattgga tatactagtg ctaaatcagt atactcatct attaagcgtc taaccgcttt
    41041 aaatatattt tccatgggtt gcccgatatt ttctcgtcgg tgtgctgtca taagaatgaa
    41101 ttttttgtca tgatatttat ccatgatgtt agatttataa ttgtcatcaa ctgtatattt
    41161 catagcatca atcgctgtat taccagtgac aacaacactt tctgaatatt tcccttcact
    41221 taacaaatgc gatgcagcat ttttagtagg tgcaaaatgt aagtcagcta atacaccaac
    41281 taattgtcta ttcacctctt ctggaaaagg tgaatattta tcataacttc taagccctgc
    41341 ttcaacgtgt ccaatcggca cttggttata aaatgccgct aaaccacctg caaatgtcgt
    41401 catcgtatca ccatgtacaa gtaccatatc tggtttttct aattgaatca cttgttctaa
    41461 ttgagtgatt gatttagaag ttatctcaga aagtgtctgt cctgatttca taatattcaa
    41521 atcgtatttt ggtttgattt caaaggtact taatactgaa tcaagcattt ctctatgctg
    41581 tgctgtaaca acaacaattg gctcgagcat tttttcttgt tccaaagctt taactaaagg
    41641 agccatcttt atggcttcgg gtcttgttcc aaatatggtc ataatctttt tcatcaaact
    41701 acttatctcc gattcttcta tttagtacca aacaatctat ctccagcgtc gcctaaccct
    41761 ggtgtgatat atgctttatc atttagcttt tcatcaagtg cagcaatata aatatctaca
    41821 tctggatgtg cttcatgcat cttttctacg ccttctggtg ctgcaattaa acacatgaag
    41881 cgaatatttt tagcgccacg tttcttcaat gaagtaatag cttcaattgc tgatgcgcct
    41941 gttgctaaca taggatcaac aacaatgatt tgtctttcag taatatcttg aggtaactta
    42001 gcaaaatact ctacagcctt taatgtttcg ggatctcgat acaaaccgat atgtccaact
    42061 ctggctgcag gcactaaact taaaatacca tcagtcatac ctaaaccagc tcttaaaatt
    42121 ggaacgatag ctaatttttt accagctaat cgtttagccg tcattttagt tacaggcgtt
    42181 tcaatatcaa catcctgaag ctctaagtct ctagttactt catatgccat caacatacca
    42241 acttcgtcta caagttctct aaattcttta gtacctgtat ttacatctct aatatagctt
    42301 agtttgtgtt gaattaatgg atgatcgaaa acgtgtactt tactcataaa aattactcct
    42361 atctttgtgt atgtttattg atatagagga tattcagctg ttaatttcgc aacgcgttct
    42421 ttagcttgtt gtaatttttc ttcatcttta ctatttttca atgctaaact gatgattttt
    42481 gcaacttcct caaaagcttt ttcatcaaat ccacgcgttg ttgcagcagg tgtacctaaa
    42541 cgtataccac tcgttacaaa aggtttttct tgatcgaacg gaatggtatt tttgttacat
    42601 gtgataccaa ctgaatctaa agtctcttca gcttctttac cagtaagtcc tatagaccct
    42661 tttacatcaa cagctactaa gtgattatct gtaccgccag aaacaattct aaatccttca
    42721 ttaattaatg cttctgcaag aacttttgcg tttttaacca cttgttgttg atacgttttg
    42781 aaattatttt ctaacgcttc tccaaaagca actgcttttg ctgcaataac atgctcaaga
    42841 ggtccacctt gaataccagg gaaaattgtt ttatctatgt cttttttata ttcttcctta
    42901 cataaaatca taccaccacg tggtccgcgt aatgttttgt gtgttgtagt tgttacaaaa
    42961 tcagcatatt ctactggatt tggatgtaaa cctgccgcta ctaatcctgc aatatgtgcc
    43021 atgtctacca ttaacttagc gtttacttca tctgcgattt ctttaaactt tttgaagtca
    43081 attgttcttg aatatgctga tgctcctgcc acaataagct taggcttatg ctctaacgct
    43141 aatttacgaa cttcatcata attgattcgt tctgtgtctt tatctactcc atattcaacg
    43201 aaattgtaga atttaccact aaaattaaca ggcgctccat gtgtcaagtg accaccatga
    43261 ctcaaattca tacctaaaac cgtgtcgccc atttctaatg caactaagta aacagccatg
    43321 ttcgcttgcg aacctgaatg tggttgaaca ttgacatgtt cagctccaaa caatgctttt
    43381 gcacgattaa ttgcgatgct ttcagtaaca tctacaaact cacagccacc ataatatcgg
    43441 cgtcctggat agccttcagc atacttatta gtcaacactg aaccttgtgc ttccataacc
    43501 gcttccgata caaaattttc cgatgcgatt aactctatgt tgctattttg tctctgaaat
    43561 tctctctcga ttgcttctgc gataacttta tcttgcttgg tgatataaga cataaaatct
    43621 ccccttcttt caaaaaaact tattggtatt tagcacgttc gccaccaatc tttttcggcc
    43681 tagatgtggc aatagttaca attgcctgtc ctacttgctt tactgaggtc cttacaggta
    43741 cacatacatg tttaatatgc atgcctatta atgtttgacc aatatcaatt ccacaaggaa
    43801 cagtaatatg ttcgaccacg atcggatcct tcatatgctg aaaagcgtat gttgccaaac
    43861 tccctccagc atgtacattt ggaacgacgg aaacttcttc cattgttaat ggattatact
    43921 gagatttttc tattgttatc gctctgttga tatgttcaca tccttgaaaa gcaaaagtaa
    43981 cgcctgtctc tttactcaca acatctaatg cattaaaaat agtttctgca acttccatcg
    44041 aaccgacagt cccaattttt tcgccaatga cttccgatgt tgaacatcca attaaacata
    44101 tatctccttt gttaaaaaag gacatatctt ttaattcgtc taataacatt gtcaaatctt
    44161 tcataaaagc ccacccttcc taaaaataaa aaaggaatat agcaaagtgc tacactcctc
    44221 tattataact tatttaactg ttaacatata ctaattatac agaattccta ctagcaaata
    44281 atatctttta attttaaaat taaactcaca agttcttcat aggtatgtac atacatttct
    44341 tttgttccac cgtatggatc tataacttct cctgcttctt ttacatattc atgcaatgtg
    44401 aaaacatgat tttgcaaacc aaattgtgcc tctattaatt ctttgtgcga atacgacatc
    44461 gtcaaaataa tatctgcttt caaatctgct tcagtaaatt gttgcgataa ggtcgtttca
    44521 gctaaatgat gttcttcaac tatgtcttca acataattcg aaacaccttg attgttcaca
    44581 gcgaatatac ctcttgattc aaattgatga tttggcataa cctcttttgc aatactttcc
    44641 gctaatgggc tacgacatgt gttacctgta caaacgaata aaatcttcat agttcacacc
    44701 ctttaacaat gtgattacct gcagctttta acatgcgatt cataattgct tctgtattat
    44761 cattcagctc aaagccgtat atatacgccg ctgaaatatt ttcattttca tcaagtgaat
    44821 gtaacacatc ataaagatta tgacttgctt gtttaacatc attgtcatcc tgacacaatt
    44881 gaatgaattg cgcttcactt ggtataaacg ccaccttatt actcggcaca ataaaagcta
    44941 tagaagacca atctttaccg tcatttccaa ttttgctctc aatatctgta ataattgtaa
    45001 gtggtgtatt gggtgagtaa tgcttatact tcatacctgg tgcaattggc tgttcagtat
    45061 cattataatc agcatgggtg atactattcg gaagtatatc tgtaatcatt gctgctgtta
    45121 tagaaccagg tcttgcaatt ttataaggaa aagatgtgca atctaaaacc gtactttcta
    45181 atccttcttc actttgttca gcttgaacga taccatctat acggccattc aaatcttgat
    45241 atacatgatt gaaagttgtt ggtgaaggtc taccacttaa attagcactt ggagcagcta
    45301 gaggttcatt tatgatttgt aataattgtc tacctacaga atggcttggc attctaacag
    45361 caactgatga taaacctcca gaaacttttc gacatagata gcctggcttt aacggcaata
    45421 taaacgaaat agggcccggc cagaatgcct gcattaactt ttctacgggt gcatctaaaa
    45481 tatatgtaaa atcttttaat tgatctttac tgtgtatatg aacaataagc ggattatcag
    45541 atggacggcc tttagcttca tatattttag ctacagcttc ttcatctgtc gcatttgctg
    45601 caagtccata aactgtttca gttggtaaac ctattaaacc accgtttaaa acaatgtctt
    45661 ttatttcatt aattttagga tattgctgta aatcttcatt atattctcta acatcccaaa
    45721 ttttagtatc caacttaatc acgcctttct tatttatcat aatataaagc aaaaagctat
    45781 gcacttaact aatcatagca aaggcataac ttctaattac catttaaatg agacgattcg
    45841 atcgtggcca tttatatctt taataatgtc gatttttttg tcaggaaatt tatttaaaat
    45901 tattgattta agtgcctcac cttgattgta accaatttca aaaacaactg ggctgccttt
    45961 ttccataacg tgaggtaaat cttcaatgat tgattcataa atagcatatc catggttatc
    46021 tgcaaacaat gcctgatgtg gttcgaatct cgtaaccgtt ggagacatcg taaccatatc
    46081 tttttcatct atatatggtg gattagatat caagccgttc aacttgatac cttcattaat
    46141 taagggcttt aatgcatccc ctgttaaaaa ttgtatttgt gattgatgct tctcagcatt
    46201 attacgagcc atattcattg cttcaagtga aatatcagta gcaataacat ttaaatccgg
    46261 cttttcacat ttcaaagtaa ttgcaagtac accactaccc gttccgatat ctacgattgt
    46321 tgcatcatct tctaactgtt gtaagaaatg caacattact tcttcggttt caggtcttgg
    46381 tatcaaacaa tttgagttta catcaaacgt tctaccataa aatgaggcaa agccaactat
    46441 atactgtata ggctctccta ataacatacg ttgtaatgct aagtcgaact tcataatcat
    46501 cgctttcggc atatcatcat gcatgtggac tacaaagtcc gtacgcgtcc attgaaatac
    46561 atctaacatt aaccattcag ctcgtgtttg ttcaaaccct ttttgttgtg ttaaatgaat
    46621 tgcttcatct aacttttctt tataattcac cattattaag ttctttcaat ttatctgtct
    46681 gctctgataa agtcagtgca tctataattt cttctaaatg gccttccata atttgcccta
    46741 atttttgaag cgttagacct atacgatggt ctgttacacg gctttgtgga taattataag
    46801 ttcgaatacg ttctgaacga tcaccagtac cgactgctga tttacgttgt gacgcatact
    46861 tttgttgttc ttcttgaact ttcatatcgt ataaacgtgc ttttaacact ttcattgctt
    46921 tttcacggtt ttgaatttga gacttctcag aagatgttgc aatgacacca gttggtaaat
    46981 gggtaatacg tactgcagag tcagttgtgt ttacgtgctg accacccgca ccacttgaac
    47041 gatacgtgtc gatttttaaa tcttcatttc taatttcaat ttctacatct tcaacttctg
    47101 gtaaaactgc cactgtagct gttgaagtat gaatacgtcc acctgattct gtttcaggta
    47161 cacgttgaac gcggtgcgca ccattttcaa atttcaattt actatacgcg ccattaccag
    47221 aaactgagaa actaatttct ttgtaaccac catggtcact ttcagacgct tctactattt
    47281 cagttttgaa tccttgtgat tcagcatact ttgaatacat acgcattaaa tcaccagcaa
    47341 aaatcgcagc ctcatcacca cctgctgctg ctcttatttc tacaataacg tctttgtcat
    47401 cattaggatc tttaggaatc aataatattt taagctcttc ttcaagattt ggaagttcag
    47461 ctttaatacc attactctcc tcttttaaca tttctacttc ttctttatca tcagtctcac
    47521 ttaacatttc ttcaatatca gctaattctt cttttttagc tttatagtta cgataaacat
    47581 ctacagtttt ttgtaaatca gcttgctctt tagaatattt acgtaattta tctgaatcat
    47641 ttacaacatc tgggtcactt aacagttcat ttaactgttc gtatctttct tctacaatat
    47701 ctaattgatc aaacacttat aattcctcct tattattatc actaggtgct acgatatggt
    47761 gcgcgcgaca acgtggctca taactttcat tggcacctac taagataatc ggatcatcga
    47821 ttttagctgg tttaccattt attaatcgtt gcgttctact agatgaagaa ccacaaacag
    47881 cacaaactgc ttgaagtttc gttacttgtt cactgacagc catcaattta ggcattggtt
    47941 cgaacggttc gcccctaaaa tccatatcta atccagcaac aataacacgg tgtccatctg
    48001 ctgatagttt ttctactata cttacaattt catcgtcaaa aaattgcact tcgtctattc
    48061 ctataacatc aacattagtt aagtcgtgcg tcataatttc acttgcttta gaaatattaa
    48121 tcgcttcaat ggcattacca ttatgagaga ccactttttc tttatgatat cgatcatcaa
    48181 tcgccggttt aaatacaacg actttttgtt tagcgtatat accccttctt agacgtctta
    48241 ttagttcttc ggatttaccg ctaaacatac tacctgtaat acattctatc caaccggaat
    48301 ggtaagtttc atacattgag agttccacct ttttcaaaac ataatcgctt tattatatca
    48361 tatttcaaat attcataaat gtctttttca taattatatc gatattgtac atgaacaatt
    48421 attttataaa tttgtcttgc atatttatat acagctattc taatttgttg cttcttattc
    48481 gtgcgttgtt tctactcaat acaaacttta ataaagggga aatttatcat tatgtattaa
    48541 caacatggta ttgagtcact tctttgaaca cagtcgtaag tatataccct tactacgctt
    48601 ataaataaaa aagctgtcta caattccatt ataggatgca gacagcttaa cgattactat
    48661 attagttgtt tgatttaaga ccaaactttt tgttgaaacg ttccacacgt ccatccgcag
    48721 cagcgaattt ttgacgtcca gtgtagaatg gatgtgaatc agatgaaata tctaaacgaa
    48781 taactgggta ttcttttcca tcttcccact ccatcatttc tgaagatgtt tttgtagaac
    48841 cgcttaagaa tttgaagttt gtagtagtat ctaaaaagat tacttggtga tactcaggat
    48901 gaattccttg tttcattatt ttcagctcct ttgccctgaa ccatctggaa cagagttatt
    48961 tgtgagtttt tacccaatac tgtgtaatta taaaggtaat taattcaaaa cgcaagcccc
    49021 tatataatgt ttattaaatt ataggtcgac ccgttttagt actttcttct gcagactttt
    49081 gtagctgctt gaagaaatct tcattattct tagacctttt aagtttgcga ataaatcttt
    49141 cagtaaagtc tgttgagtca gtgaatagat ttcttaattg ccataatgtg tctaattcag
    49201 atttacttat caacaattct tctttacgcg ttgaacttct gccaatatca attgcaggga
    49261 aaatacgacg ttcagacaat ttacgatcta aatgtaactc catgttacct gttcctttaa
    49321 actcttcgta aatcatatcg tccatacgtg aacccgtatc aactaatgca gttgcaagta
    49381 ttgttaaact tccacccgct tcaatatttc tcgctgcacc gaagaatgct tttggtttgt
    49441 gtaaagatgc aggatctaaa ccacctgata atgtacgacc acttggtgga ataactaagt
    49501 tataagcgcg tgctaatctc gttatagaat ccattaaaat aatgacatct tccccaattt
    49561 ctactaaacg ctttgcacgt tcaagtaata attcagctac tttaacatgg tgttctggtg
    49621 gttcgtcaaa cgttgaatga acgacttcag cagcttctac tgagcgttct aaatctgtta
    49681 cctcttcagg acgctcgcca actaacaaaa taaatagctt tgcatctggt ttgttcgtac
    49741 tgattgcatt cgctatctct tttaataacg atgttttacc tgctttaggt ggcgccacta
    49801 ttaaaccacg ttgacctaaa ccaatcggtg ttactaaatc catgatgcgc gttgaataat
    49861 tttgtgtttc tgtctctaat ttaatacgct catctggata aagtggtgtc aaagcttgga
    49921 aatgcggacg tttcttcact tcttctgcgt tatggtcatt aacaaagtca acttgtaata
    49981 agccataata tttttcgtta tctttaggtt ttctaacttt cccagttact ttatccccac
    50041 gtttaatttc aaaacgacga atttggctag cagatatata aatatctttt tcccctttag
    50101 aatagttcac tgttcttaaa aaaccataac catctggttg tatatcatct aagatacctt
    50161 ccatataata gttaccatct ttttccattt gtgcttccat aatagctaga acaagttctt
    50221 ttttatttaa tttactatag ttcgtcaact taagagtttt agctttttga gtgagttcct
    50281 tggtagtata gttcttgtac aattcgtgga atgattcata ctgaggagat gtacgttctc
    50341 tttcaggcat atagtttaca cccatttcat tattttttag ttagtaagta atagataggc
    50401 atgacaatgc ataaataact gtgctagcac aatcccatta tgctaatccc caacctttta
    50461 aatacatgaa taactatagc aaatttttat tttaattaca aaatctattt ataaaaattg
    50521 caaaattaaa acagtacaca aaacttaatt agtcatgtgc actgttttat tgcgattttt
    50581 aattcaaaaa tcaaatttat ttaaaatagc cagctataga tttcacttct aagaactctt
    50641 caataccata atcgccccat tcacgaccta aaccagattg tttatagcca ccaaatggta
    50701 agtctggctt tctgcctgct tcatttattt ctactgtacc tgcttcaata gaacgagcta
    50761 ctttatgcaa tgtttctttg ttcttaccaa taacatatcc tgccaaacca tattttgtat
    50821 catttgcaat ttgaatcgct tcatctaaat cgttataagt gataactgac attactggcc
    50881 caaaaatttc ttcttgtgct atcgtcattt gattatctac attaataaaa attgtcggac
    50941 gtgcaaagta tcctttttca agtccttctg gtttaccagg accaccataa aataattcag
    51001 caccttcttc aataccttta ttaatataat tttgtacttg atcaaattgt tttttactaa
    51061 tgatagggcc tacttgtgta ccatcttctc ttggattacc gacacgcact tggctaaatt
    51121 gttcttttaa ttcagctaag aatgcatctt taattttgtt aggcactaaa acacgtgtac
    51181 cagctgtaca tacttgacca gtattattaa caactttgcc tgttgttgct ttagccgctt
    51241 ctttaatatc tacgtcatct aggacgatgt atggtgattt gccaccaagc tctaatgata
    51301 cctttttaaa atatttagca gctttttcca taattttaga accagtaggg cctgatcctg
    51361 taaatgacat catgcgtact ttaggatgct cagataaagg attcccaacg ccagcaccat
    51421 caccattaac aaggttaaat acacctttag gaacaccgac tttatcaaaa atctcagcta
    51481 aaataacagc tgcaaatggt gtttcttcag atggtttaag tacaactgga ctaccagccg
    51541 caaatgctgc tgctaatttt aatgatgttt ggtttgtagg gaagttccac ggtgtaatta
    51601 agccagatac accgattgct tctttaacaa ctaaatcatc tccgcggcgt tcttcaaatt
    51661 cgtagttatc taatgcgtct ctcgctgcaa caaaatggtt tagtcccatt tgataatgga
    51721 cacgctcaga taatgataaa ggagcaccta attcatccgt aatagcttgt acaatatcgt
    51781 cttttctgtt ttcatattct tttacaattt tatctaataa cgcttgtctt tctttcacag
    51841 atgtatgacg gaactctaaa taaacatcgt ctgccgcctc gacggcttta tcaacatcag
    51901 ctttattacc tttagcaact ttcccgatta cttcttcggt tgctggattt ataacttcta
    51961 tcgtttcatt actattactt tctacccatt cgccattaat gtattgcttt gtgtagtctc
    52021 tcattattct ttcactcctc aagaatgatt tatatattat ttatccgtaa tgcatacgat
    52081 ataaacatta cattccatta tgatacgctc ccttttaata tgttcaaaat aaaatgcttt
    52141 aaaattttgc tgcatctaat tttttatatt tttaaataaa aataactatt ccttcatcat
    52201 cgcaaataat gcgaagactt agaaatagtt ataatcaatg ctatgtttaa acgtcatgta
    52261 attatttagc agtacgttga tctgttaaat cgacatatga ttgcgcccat gcttcaattg
    52321 gatgtaaagc ctctgctaac gctttacctt tttcagttag tacataaata atttgtactg
    52381 gactcgtaga aatgatttgc ttctcaacta actcccattg tgcaagctct gacaacttaa
    52441 gacttaaagc acgtggcgtt attgttttca aatctctttt catatcggaa aagtgtgctg
    52501 aacagtcatt acatcttgag agataattaa tgattaatcc attccaactt ctaccaagta
    52561 ttttaaaagt ttcttcgaga tacggacata cttccatcat cttcacctct catcaataaa
    52621 tttagaatgt aaacgaacac ccttttttaa tcagtataat tattatacca caaaacaaga
    52681 taaatctata cagtttccgt ccaaatatct gcacctaaag cttttaagtt ttctacaata
    52741 tctgtataac ctctataaat atgttttaca ttgtaaattg tagttacacc ctcagcaatt
    52801 aaaccagcaa taattaaaca agctcctgct cttaaatcgc tagcataaac ttcagcacca
    52861 tgtaatgttg atggttttat cgttgctgtg ccttcgtcaa cttcaatatt tgcacccatg
    52921 cgctttaatt cttcaacatg tttaaaacgc tccggataaa tcgtatcagt tacaaatgaa
    52981 ggaccatttg ccataaataa taatggtgta ataggctgtt gtaaatcagt agcaaaacct
    53041 ggatatacta gtgttttaat atcaacaaat tgatatggtg cattattatt gatacgaatt
    53101 ctttcgtctc ttacatcaac attcacacct aattcactaa atttagcagt taatgtttct
    53161 acatgtttcg gaacaatatt atttaatata acattttctc cacatgctgc agcgatacac
    53221 atatatgtgc ctgcttcaat tctatcaggt ataacttgat actcagaacc atgtaattct
    53281 ttgacaccat tgattttaat cgttgatgta cccgctccct taatattagc tcccatactt
    53341 gttaagaagt tagcaacatc aactacttcc ggttctttag cagcattttc aattacagtt
    53401 tgtcctgttg cataaactgc agctagcata atgttaattg ttgcacctac gctaaccata
    53461 tctagaaaaa tatgtgcacc ttttaactct ttagcttcaa ttttcattga tgtcgtactt
    53521 gattcatcaa tttcagcacc taaagcttta aatcctttaa tatgttgatc aattggacgt
    53581 ggcccaagtg gacatcctcc cggtaaacca atcacacatt ttttaaatct acctaacatg
    53641 gcacccatca tatagtatga agcacgtaat gattcaactt tattatttgg taatgcagca
    53701 ttttgtattt cagttgtatc aacttctaat tccgtaccat ttagtgatgc cttaatattt
    53761 aaatcttcta ataaactcac taaagtttta acatcagaga tttgcggtaa cccttctaat
    53821 ttcacatgtc cttgagctaa taatgttgca ggaatgatag ctacagcact gtttttcgcg
    53881 ccactgatat taacttcccc atttagtgtg cgtccacctc ttatttttat tacctcttga
    53941 gccatatcat ttatctcctt tgtccattac tttttaattt tttgcattat tagcattata
    54001 aattaatttt actttatttg taaaatagtt tattttaacc gttaaaatct tgtctttcta
    54061 ttacgattga ttaataacgc atcattcacc ttaattaata tatgatgtta ttacccgctt
    54121 gaccatggtc taaagtctga ttgttcgctc aaatattgac attattttga cagccaattc
    54181 agctttagtg ggattgcttt tgtatgtttt tattcatcaa ctacagcatt ttctatataa
    54241 ttatagcaca atcatttttt gtatatttca tcatttttag cttcaacttt taaaatgtgc
    54301 tgtatcaatt cgtgccttaa caacataaaa aagaagcaaa caccattctg tctgctcctt
    54361 tttgaaatta atatccctac gttattaata acttaaaaac taaatattaa ttatttagca
    54421 cggtttgaag taccgaactc tttaatttta cctttaactg tttctttgat agcttcacgt
    54481 gcaggtccta agtatttacg aggatcgtaa acttctttgt cgttatttaa aacgtcacga
    54541 actgcttttg ctgaagcgat ttggttttca gtgtttacgt taattttagc tgtaccaaat
    54601 ggaattgctt tttggatatc tttagtcggg ataccagtac caccgtgtaa tactaatggt
    54661 aaacctgtag ataaaccgat ttcttccatt tctttaaatc ctaattttgg ttcacctttg
    54721 tatggaccat gaactgaacc taatgctggc gctaatgcat cgataccagt tttttcaact
    54781 agttcttgac attctttagg atcagcataa atgataccgt ctgctacaac atcatcttct
    54841 tgtccaccaa cagtacctaa ttcagcttct acagaaacac ctttttcatg agcgtattca
    54901 acaacttttt tagttgttgc tacgttttct tcgaatgggc tgtgtgaagc atcgatcatt
    54961 actgatgtga aaccagcatc gatagcttct ttacattttt cgaagcttga accatggtct
    55021 aaatggattg ctacaggaat agtgatgttt aagtcatgca ttaacccttc aaccatttta
    55081 acaattgtgt agaaaccgct catgtaacga gcagcacctt cagaaacacc taaaattaca
    55141 ggtgcatttt cttcttgtga cgcttctaaa attgcttgag tgaattctag gttattaata
    55201 ttgtattgac ctaccgcata accattttct tttgcatcaa ttaacatttc tttcattgaa
    55261 actaaaggca tgaaagttcc tccttgagtg cttacgcacg tatttttcaa agtaattata
    55321 tcaaaaaaat agcgtcaatg cattgaaata ctgcagatta aatgtgtatt ttttgaaaaa
    55381 tgcgatagtt ataataaatg caaacgtata catttttata caatttaagc cgttgcataa
    55441 tatgtagtca ttaattacaa tattttataa gtagattgga ggataaagat gtcaaaaatc
    55501 ttaaacacac aactaatagg tatctttaat aggctagaaa aacaatcttt ggaaattcaa
    55561 atggctgccc aatgtttaat tcaagcaatt ggtggcgaag gttatgttta tgtaaaaggt
    55621 tatgatgatt tacagttttt cgaaagtttc attctacatg gtgatgagcg tttaaaatct
    55681 agccgaaaac ttgacgctat taaagacttt aaagaaattg actcaactga tcgtgtatta
    55741 ttattcgcac cattttataa tgatcaagtt gcattagata ttcaaaaact tatcgactta
    55801 gatatcgatg tggtcttaat aagcaacaaa cctaaaacag atgatttccc tgatcatctc
    55861 gtacatttta tcgatttatc tacaccaaga cctatagtct acactgaaga ttacgataag
    55921 attgtccaac cacatgcgat ggcattgaat tatgtatact atgacattta tacacaaatg
    55981 attgaaatga caagagactt agaattataa aagtcactat tgttatttca taccttgtca
    56041 ctaacataat attaaaatta tacgaaaaac cggtactttc aatgtttaac aatgaaagta
    56101 ccggttttat tagcaaattt atttattttg ttgatatttt aatgaagctt caataaatga
    56161 tttaaaaatc gggtgcggac gatttggtct agataagaat tctgggtgga attgacaagc
    56221 aataaagaaa tcatttgtcg gaatctctac catttctact aaacgtccat ctggacttgt
    56281 accagaaatt accataccat ttgcttctaa ttgttctcta tagtcattat taaattcata
    56341 acgatgacga tgtctttctt caatttccgc tttaccataa acatcttgtg ccaatgtacc
    56401 ttctttaatt gaacatggat ataagcctaa gcgtaatgta ccacctaaat cttcgatatc
    56461 tttttgttct ggtaataaat ctataattgg gtatggtgtt gctgggtcta gttcagctga
    56521 atgtgcgcct tcaaggccta atacgtttct tgaaaattca actgttgcaa gttgcattcc
    56581 taaacaaata ccaaagaatg gtacattgtt ttctctagca tacttaattg cactaatttt
    56641 accttcactt gcacggaaac caaatccacc tggtactaaa ataccgtcga catctgcaag
    56701 gtattcggct gcattttcat ctgttacttc acttgaatca atccatctaa tgtcaatatc
    56761 tttggcaaaa ggatatccag catgtttcaa tgattcaaca actgataaat atgcatcttg
    56821 taagctaaca tatttaccta ctaaaccaat tgtaatttta ccatctaaat tattaacgat
    56881 atctaacaac tgtttccatt catcaagctg tgtttcatat ttcgcgttta attgtaaacg
    56941 tttaataacg atatcatcca tattttgttg gcttaattgt aatggaattt cgtataaaga
    57001 gtctgcatca cgacattcaa taacactttc tttattaatg tcacagaata atgcaatttt
    57061 atcttttaaa tcttgtgtca tttcatattc agttcttaca acgattaagt ctggttgaat
    57121 acctaaacct cgtaattctt taacactatg ttgtgttggc ttcgttttca tttctccagc
    57181 agctttaata taaggcagta atgtacagtg aacatacata acattttctc tacctaaatc
    57241 actacgaatt tgacgaatcg cttcaataaa cggtaatgac tcaatatcac ctgttgtacc
    57301 gccaatttca gtgataacaa cgtctgcatt cgtactttcc cctgcaagta ataaacgttc
    57361 tttaatttca tttgtaatat gcggaataac ttgaactgtt ccgcctaagt aatcaccacg
    57421 acgttctttt ttcagtacgt gtgaatacac tttaccggct gttacatttg aaaacttgtt
    57481 taaattaata tcaataaatc tttcgtaatg tcctaagtct aggtcagttt ctgcaccatc
    57541 atccgttacg aatacttcac catgttgata aggactcatt gtacctgggt caacatttaa
    57601 gtatggatcg aatttttgaa ttgttacatt aagacctcta tcttttaata atctacctag
    57661 agaagatgct gtaataccct tccctaatga tgaaactacg ccacctgtta caaaaataaa
    57721 ttttgtcatg tcttgacctc ctaattatta aagggaatgc ttcctcatca attgtaaaaa
    57781 ttacgtaaaa cataacattt gagtaagctc attcaagttg tttgtttgtc gaattcgaca
    57841 aaattaaatt ctgtttactt accgtttcca tactgctatg tcactatgta tatcatttac
    57901 aactttgatt attgcgttat catttcttga tttactcaat taaataaaaa aacgctccct
    57961 ctcacaaatt ttgtaagggg agcgtataaa ttttatacac gtgtcctatt taaaggagcc
    58021 cgaataaaat tttatcatct ttcaactaaa agtcaaacaa aaaattatgc tttgaagtct
    58081 tcttcgtctt caaaatcttc ttcgtcttca tctagttcat cttcatcttc ttcaatgact
    58141 atatccgaat gattgatttc ttcttcaact tgctcatctt caggatcatt taattcttct
    58201 tgatcatcag tttgagctgg aatatcgtca tcatcatcca attcatcttc acccaataat
    58261 tttaagtttt gatcttcttc atcatcggcg tctaaaatat caaatttttg aattgttggt
    58321 gcaattttct cttcgatatc atctactgag taccagtcac gtaatcccca taagttttca
    58381 ccaacattta aaaaacgtcc atctgtattt aaatctgtgt aaaattgtac aacacgagtt
    58441 tcaatttcct catactcata atcacctaat gctctaaatt catcgatgat atcatataag
    58501 ttcattgttt cacctttatc attcaataat gtataagcca tatcaataaa tgatttttca
    58561 tcaaccattt gttttgtata atcttgaatt ttcattgccc aatacttcct ttcgaaggat
    58621 ataatctaaa tttatacgtc tgaattcatt tatatatagt aacaaaacta aattataaat
    58681 gacaatatca tatttcgcaa tcactgttag taatttaaat atttttcgaa aacgacataa
    58741 tcatcagttt gttcgatttc aacgaaatta ctatttagac ataatggttt aaaatcatta
    58801 ttctctccaa acagaatcat cgtaatcaca ttaaggttgt catagttttt tcttaagtaa
    58861 gttggcaatt gtcgcagcgc acttgaacca ataccattaa agcgatatga tttatccact
    58921 tcaatagcag caatgttcat gcgttcacca atctgctcca atgcgataaa gccaaccttt
    58981 tggccatcaa tcattaaatt aatgatatgt acattggtca cttctgaacg actttcttct
    59041 tcaagcttta atgacgaaac atgttttgaa tctaagtcca agtaatatag tcgttctttg
    59101 ccgattggtc cttcttcttt agtcgctgta tgcatgaatc cagcacgttc gtataggttc
    59161 caagcattgt cattttccgc atctactact agatatagat gattaaaatc aggaaataca
    59221 ccttgaacat attgcggcaa tgacatcatt attttcgtgc catatccaaa accttgatat
    59281 ttttcattaa tcgataatga acgaatataa acgacatttt caggtgtatc ataaccttca
    59341 tgctgatagt aacgatgtaa tacaaaaaag cccaccactt catttttatc gtttattgct
    59401 acgttagcaa tcctatcagc atcattaatt gcatcatcaa taacttcttt aggtaaagat
    59461 gaatatattt gttgtctttc attcaagtca aaatcattaa ttgctgaacg atattgttca
    59521 tcaaatgctt ttaaagtgat accttcaaaa caaagttctt tagccatata tttaacccct
    59581 atctttttat atatgaagca tgaatcccca tattatttta cctattattt cactacgat
//
LOCUS       DAPSKH010000007        53875 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPSKH010000007 DAPSKH010000000
VERSION     DAPSKH010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 53875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53875
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.007"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            160..957
                     /gene="fdhD"
                     /locus_tag="RPH49_000546"
     CDS             160..957
                     /gene="fdhD"
                     /locus_tag="RPH49_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDY5123737.1"
                     /translation="MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATV
                     ICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRM
                     IASCCGKSREFYFQNDAAIAKTSMSKITLTPIQIINMMTRLQSASHIYQETGGLHNAA
                     ISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGV
                     GVILSKSAPTTLAVTLANDLNITSVGFIRNGGFNIYSHPERIIDSEQ"
     gene            complement(1134..1904)
                     /locus_tag="RPH49_000547"
     CDS             complement(1134..1904)
                     /locus_tag="RPH49_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123738.1"
                     /translation="MASISMSDIYCNGTIFENDDEQLIYLTPSFPQRYTSNTWIYKKM
                     PTEERWLKDLERQHQLHTNQGSNHYAFSFPENEQLDNHWMAMFKDMNFELGIMELYAI
                     ESDALANLPRNADVEIAIVDESHIDAYLKVAYQFSLPFGKDYADAHEKMVREHYQKDV
                     IKRLVAYLNNEPIGVVDVIESENYIELDGFGVLEQFRHQGIGSTMQSLVGEYAISRDH
                     KPVILVADGEDTAKDMYAKQGYVYQSFCYQILKEDIGN"
     gene            complement(1961..2530)
                     /locus_tag="RPH49_000548"
     CDS             complement(1961..2530)
                     /locus_tag="RPH49_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000208738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDY5123739.1"
                     /translation="MTTKQLVYTALMTAIIAILGLVPVIPLPFSSVPIVLQNIGIFLA
                     GVILGRKYGTLSVIVFLLLVVAGLPLLSGGRGGIGVFAGPSAGFLLLYPVVAFMIGAI
                     RDRFINEINFWILFVGILVFGVIALDVIGTLIMGMIINIPFTKAISISLAYLPGDILK
                     AIVASLIGTALLNHSQFRQIMGLKKSYLR"
     gene            complement(2651..3592)
                     /locus_tag="RPH49_000549"
     CDS             complement(2651..3592)
                     /locus_tag="RPH49_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside hydrolase"
                     /protein_id="HDY5123740.1"
                     /translation="MTKKVYFNHDGGVDDLVSLFLLLQMENVQLIGVSTIGADCYLEP
                     SLSASVKIINRFSNEDIQVSPSYEREKNPFPKEWRMHAFFMDALPILNEPVKHVASNV
                     SDKEAFEDIIQTLKRQSEKVTLLFTGPLTDLAKALQKDSSIVQYIEKLVWMGGTFLPK
                     GNVEEPEHDGSAEWNAYWDPEAVKIVFDSDIEIDMVALESTNQVPLTLDVRQRWANER
                     QYTGIDFLGVSYAAVPPLTHFITNSTYFLWDVLTTAYIGNKDLVHSIEKKVDVISYGP
                     SQGKTFECKDGRKINVINHVDNNAFFDYITALAKKVN"
     gene            complement(3990..4898)
                     /locus_tag="RPH49_000550"
     CDS             complement(3990..4898)
                     /locus_tag="RPH49_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDY5123741.1"
                     /translation="MKKLLLPLIIMLLVLAACGNQGEKNNKAETKSYKMDDGKTVDIP
                     KDPKRIAVVAPTYAGGLKKLGANIVAVNQQVDQSKVLKDKFKGVTKIGDGDVEKVAKE
                     KPDLIIVYSTDKDIKKYQKVAPTVVVDYNKHKYLEQQEMLGKIVGKEDKVKAWKKDWE
                     ETTAKDGKEIKKAIGQDATVSLFDEFDKKLYTYGDNWGRGGEVLYQAFGLKMQPEQQK
                     LTAKAGWAEVKQEEIEKYAGDYIVSTSEGKPTPGYESTNMWKNLKATKEGHIVKVDAG
                     TYWYNDPYTLDFMRKDLKEKLIKAAK"
     gene            complement(5111..6265)
                     /locus_tag="RPH49_000551"
     CDS             complement(5111..6265)
                     /locus_tag="RPH49_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA/acyl-ACP dehydrogenase"
                     /protein_id="HDY5123742.1"
                     /translation="MNDMDNSFLITTEIQRKWIEKFKVIGDTFKAKAEYNDQHSQFPY
                     KNIEWLIKEGYGKLTLPKEYGGEGATIEDMVILQSFLGELDGATALSIGWHVSVVGQI
                     YEQKLWSQDMLEQFAVEINNGALVNRAVSEAEMGSPTRGGRPSTHAVKADDGYILNGV
                     KTYTSMSKALTHIIVAAYIEELESVGFFLVDRNLPGVEIADNWDVLGMRATESHDLIL
                     NDVKVPLKHLVETEKSKAPNGWILHIPSCYLGIAQAARNYAVDFAIQHSPNSIEGTIA
                     TLPTVQQNLGKMETLLLCARQFLWSTAKGYQQYTDESQIRNATSASKVMVMNQGLEVI
                     DLAMRIVGAKSLEMNRPLQRYYRDMRAGLHNPPMEDAAYTNIAKSITDTF"
     gene            complement(6482..7387)
                     /gene="yut"
                     /locus_tag="RPH49_000552"
     CDS             complement(6482..7387)
                     /gene="yut"
                     /locus_tag="RPH49_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016266007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urea transporter"
                     /protein_id="HDY5123743.1"
                     /translation="MKMIDVLLKNISQVVLISNKWTGLFILIGLFVADWTIGLAAIVG
                     SIIAYTFARFINYSEAEINDGLAGFNPVLTAIALTIFLDKSGLDIVITMIATLLTLPV
                     AAAVREVLRPYKVPMLTMPFVIVTWFTILLSGQVKFVDTSLKLMPQNIETVNFSNNDR
                     IHFIQSLFEGFSQVFIEASVIGGVCILIGILIASRKAALLAVIASLLSFIIVALLGGN
                     YDDINQGLFGYNFVLMAIALGFTFKTEINPYISTFLGVLLTVVVQLGTTTLLEPFGLP
                     ALTLPFIIVTWILLFAGIKHDKVDA"
     gene            7647..7949
                     /locus_tag="RPH49_000553"
     CDS             7647..7949
                     /locus_tag="RPH49_000553"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit gamma"
                     /protein_id="HDY5123744.1"
                     /translation="MHFTQREQDKLMIVVAAEVARRRKARGLKLNHPEALALISDELL
                     EGARDGKTVAELMSYGRQILNKEDVMDGVEHMITDIEIEATFPDGTKLITVHHPIV"
     gene            7963..8373
                     /locus_tag="RPH49_000554"
     CDS             7963..8373
                     /locus_tag="RPH49_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit beta"
                     /protein_id="HDY5123745.1"
                     /translation="MIPGEIITKSTEIEINNHHPETVIEVENTGDRPIQVGSHFHFYE
                     ANAALDFEREMAYGKHLDIPAGAAVRFEPGDKKEVQLVEYAGKRKIFGFRGMVNGPID
                     ESRVYRPTDENDEYAGVFGDNGAENVNKKGGKRS"
     gene            8370..10085
                     /gene="ureC"
                     /locus_tag="RPH49_000555"
     CDS             8370..10085
                     /gene="ureC"
                     /locus_tag="RPH49_000555"
                     /EC_number="3.5.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002447295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease subunit alpha"
                     /protein_id="HDY5123746.1"
                     /translation="MSFKMTQNQYTSLYGPTVGDSIRLGDTNLFAQIEKDYAVYGEEA
                     TFGGGKSIRDGMAQNPRVTRDDVNVADLVISNAVIIDYDKVVKADIGIKNGYIFAIGN
                     AGNPDIMDNVDIIIGSTTDIIAAEGKIVTAGGIDTHVHFINPEQAEVALESGITTHIG
                     GGTGASEGSKATTVTPGPWHIHRMLEAAEGLPINVGFTGKGQATNPTALIEQINAGAI
                     GLKVHEDWGATPSALSHALDVADEFDIQIALHADTLNEAGFMEDTMAAVKDRVLHMYH
                     TEGAGGGHAPDLIKSAAFSNILPSSTNPTLPYTHNTVDEHLDMVMITHHLNAAIPEDI
                     AFADSRIRKETIAAEDVLQDMGVFSMISSDSQAMGRVGEVITRTWQVAHRMKEQRGPL
                     DGDFEHNDNNRIKRYIAKYTINPAITHGISEYVGSIEPGKLADIVLWDPIFFGVKPEL
                     VVKGGLINSAVNGDANGSIPTSEPMKYRKMYGQYGGNLTSTSMTFVSKTAYENGINRA
                     LNLKRMVRPVKNIRQLSKADMKNNSATPKLDVDPQTYEVYVDGEKITSNAATELPLTQ
                     RYFLF"
     gene            10098..10550
                     /gene="ureE"
                     /locus_tag="RPH49_000556"
     CDS             10098..10550
                     /gene="ureE"
                     /locus_tag="RPH49_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreE"
                     /protein_id="HDY5123747.1"
                     /translation="MIVEEIQGNIANLSNSEKQKHVEKVYLENSDLVKRIQRVVTDHG
                     TEIGIRLKQPIDLQYGDILYADDHNMIIVDVNSEDLLVIQPRTLQEMGDIAHQLGNRH
                     LPAQFTETEMLVQYDYLVEDLLKSLGIPYVREDRKVNKAFRHIGHSHD"
     gene            10543..11232
                     /locus_tag="RPH49_000557"
     CDS             10543..11232
                     /locus_tag="RPH49_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreF"
                     /protein_id="HDY5123748.1"
                     /translation="MIDHTHLRLFQFCDSQFPTGAFSHSFGLETYIQRNIIHDDHTFI
                     AWLKMFLQEQLTYSDGLAMRLVYDALENDDTQKVLHIDKLMFVQNLPKETRVGAKQMG
                     TRMVKLALELYNSPWIAWYHQQMQDKKAKLNPAICFTMLGHYLGVDIETIIDYYLYQN
                     VSSLTQNAVRAIPLGQTAGQKIVTHMIPYIEETRKQIFELKEADFGMTAPGLELNQMA
                     HENVNVRIFIS"
     gene            11245..11859
                     /gene="ureG"
                     /locus_tag="RPH49_000558"
     CDS             11245..11859
                     /gene="ureG"
                     /locus_tag="RPH49_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreG"
                     /protein_id="HDY5123749.1"
                     /translation="MANPIKIGIGGPVGAGKTQLIEKVVKRLSKEMSIGVITNDIYTK
                     EDEKILVNSGVLPESRIIGVETGGCPHTAIREDASMNFAAIDELLERHDDIELIFIES
                     GGDNLAATFSPELVDFSIYIIDVAQGEKIPRKGGQGMIKSDFFVINKTDLAPYVGASL
                     EQMAEDTKVFRGKRPFTFTNLKTDEGLDEVIDWIERDTLLKGLS"
     gene            11859..12695
                     /locus_tag="RPH49_000559"
     CDS             11859..12695
                     /locus_tag="RPH49_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urease accessory protein UreD"
                     /protein_id="HDY5123750.1"
                     /translation="MDEQQWTGQLDLTVFFDGNRSVSRDIFFEKALKVIRPVYLNQST
                     IPTFYIVNVGGGYLDGDRYRMNVNVEDNAKVTLTSQGATKIYKTPSNHVEQYQTFNLK
                     DNAYLEYVADPIIAYENAKFYQHNTFNLNNSSSLFYTDILTPGYSKTGEAFKYQYMHL
                     INEIYIEDELVTYDNLLLNPNKQSINEIGYMEHYSHYGSAYFIHEDVNQKLIDSVYET
                     ISSYSNTFDCRVAISQLPTHGFAVRIFAYRTQIIEKILGTIQSYIAENIYDRKLDFLR
                     KY"
     gene            complement(12884..13231)
                     /gene="sarR"
                     /locus_tag="RPH49_000560"
     CDS             complement(12884..13231)
                     /gene="sarR"
                     /locus_tag="RPH49_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarR"
                     /protein_id="HDY5123751.1"
                     /translation="MSKINDINDLVNATFQVKKFFRDTKKKFNLNYEEIYILNHILRS
                     ESNEISSKEIAKCSEFKPYYLTKALQKLKDLKLLSKKRSLQDERTVIVYVTDTQKANI
                     QKLISELEEYIKN"
     gene            complement(13659..13985)
                     /locus_tag="RPH49_000561"
     CDS             complement(13659..13985)
                     /locus_tag="RPH49_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PH domain-containing protein"
                     /protein_id="HDY5123752.1"
                     /translation="MILDNVNPNDLFPTEKKGPSVLGIIEYQVQGENEFEGAFIATNE
                     RLIMNVDMNGQFYYRSISYNEIEKIDYDGQTIMFKFNIGNVPMHDIKSDNVEMFVEYV
                     KQHMIV"
     gene            complement(14049..14792)
                     /locus_tag="RPH49_000562"
     CDS             complement(14049..14792)
                     /locus_tag="RPH49_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SarA family transcriptional regulator"
                     /protein_id="HDY5123753.1"
                     /translation="MSKFKVKRLTAHILMLKVINDMLKYSFHLTLTQVKLLNLLVKYD
                     NSDSNSASIDRLLKMKEIQSKMALLQMLSYLNNHQWLLKGRDQRDQRKLTISINKMHI
                     DKIEYMNNELSDYIERYFGQYTFDFSCDYVSYLLSSQELFRNLKCYLNMCQLSLEELY
                     VLGILNLHKGQLTVKELQGEFHHPIFAVSPILKCLILKGLVKKERCELDERRVIVTIK
                     REKFSKVTMLIQACYNYLEKGIQVKLNNK"
     gene            complement(14818..16773)
                     /locus_tag="RPH49_000563"
     CDS             complement(14818..16773)
                     /locus_tag="RPH49_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5123754.1"
                     /translation="MTDNYSLHIFKSMKMSSVKEANLKIIYWLQGTGVVSINLQQYDV
                     KRNDVTVIMLNDLYQIDGHDDSVCCVVEVSAKTFLKFMNANYMMRGKILTNEVASTFR
                     ILIKYLIYSKIKQQPYNANDKIINYMCVELMSLNTYDGSRHLVAEEVHDYLTNNHHKK
                     INRKDVINQVSITNKALSDMFKATPYSNFIQYLNHIRLEYCLIDILTSKKPIEEIASS
                     HGFNHYSRFIHLFKETYGDTPKLIRKRYSPTSHSIYHSQLVEIDKNIIELFDDTNQSS
                     SSMREIDIPFEPTKRSQMYQPKNIYIKGSNFYWMDYYTIKQIIQRLSVNPENLHIIVT
                     IDTSNELSIEQITLLLQKIVNYNVNVVFRIKHEYKELLTSTERGKIEKLVATIFNMTF
                     ESNRCKIGFLINDLNTTAIQKLKRLIDNYIGVFELIYHLEPNELNVRYYKEIDHLIDY
                     FILPLRQIEQVSIARSKIICDVDLINENDDLKEKITMSDINKITELLTNYTKFRGLIM
                     HMSIISEASKEINLTRLSIFIFIINILNQLRGIVIYQNDTMIVTKFKHEVQCVICLPA
                     ALLNENSDAIRLSCKSLQQFSHAKTKQIVLSIDKDNHTSENGVLVNDIMQQHSYWKAN
                     FIERNIYDHSLMVSSNSIVHLKYHLEI"
     gene            17383..18192
                     /locus_tag="RPH49_000564"
     CDS             17383..18192
                     /locus_tag="RPH49_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5123755.1"
                     /translation="MKKIATATIATAGFATIAIASGNQAHASEQDNYGYNPNDPTSYS
                     YTYTIDAQGNYHYTWKGNWHPSQLNQDNGYYSYYYYNGYNNYNYNNYNNGYSYNNYSR
                     YNNYSNNNQSYNYNNYNSYNTNSYRTGGLGASYSTSSNNVQVTTTMAPSSNGRSISSG
                     YTSGRNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAARAGYTVNNTPKAGAIMQT
                     TQGAYGHVAYVESVNSNGSVRVSEMNYGYGPGVVTSRTISASQAAGYNFIH"
     gene            complement(18210..18452)
                     /locus_tag="RPH49_000565"
     CDS             complement(18210..18452)
                     /locus_tag="RPH49_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123756.1"
                     /translation="MTKLIENLKASIFVSTLTKNLSMYSRFDVPKFGCVNGCMLFILY
                     YRVNRIGENRNFEIFTNSIFFIEIKKANKALETLLA"
     gene            complement(18626..20026)
                     /gene="nhaC"
                     /locus_tag="RPH49_000566"
     CDS             complement(18626..20026)
                     /gene="nhaC"
                     /locus_tag="RPH49_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDY5123757.1"
                     /translation="MMTRKPTFLESISTMIVMVIVVVTGFVFFDIPIQVLLIIASAYA
                     TWIAKRVGLTWQDLEKGIAERLNTAMPAILIILAVGIIVGSWMFSGTVPALIYYGLDL
                     LNPSYFLISAFFISAVTSVATGTAWGSASTAGIALISIGNQLGIPPGMAAGAIIAGAV
                     FGDKMSPLSDTTNLAALVTKVNIFKHIHSMMWTTIPASIIGLLVWFIAGFQFKGHSND
                     KQIQTLLSELAQIYQINIWVWVPLIVIIVCLLFKMATVPAMLISSFSAIIVGTFNHHF
                     KMTDGFKATFSGFNDSMIHQSHISSSVKSLLEQGGMMSMTQILVTIFCGYAFAGIVEK
                     AGCLEVLLTTISKGIHSVGSLICVTVICCIALVFAAGVASIVIIMVGVLMKDLFEKYQ
                     VSRSVLSRTLEDSSTMVLPLIPWGTSGIYYTNQLHVSVGEFFIWTVPCYLCAIIAIIY
                     GFTGIGIKKSSNSRLT"
     gene            complement(20121..21203)
                     /locus_tag="RPH49_000567"
     CDS             complement(20121..21203)
                     /locus_tag="RPH49_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD/NADP octopine/nopaline dehydrogenase family
                     protein"
                     /protein_id="HDY5123758.1"
                     /translation="MKIAIVGSGNGAVTAAVDMVSKGHDVKLYCRNQSISKFQNAIEK
                     GGFDFNNEGDERFVKFTDISDDMEYVLKDAEIVQVIIPSSYIEYYADVMAEHVTDNQL
                     IFFNMAAAMGSIRFMNVLEDRHIETKPQLAEANTLTYGTRVDFENAAVDLSLNVRRIF
                     FSTYDRSCLNDCYDKVSSIYDHLVKEESLIKTNLENGNPEVHPGPTLLNVGRIDYAGE
                     FALYKEGITKHTVRLLHAIELERLNLGRRLGFELSTAKESRIERGYLERDKEDEPLNR
                     LFNTSPVFSQIPGPNHVESRYLTEDIAYGLVLWSSLGRVIDVPTPNIDAVIVIASTIL
                     ERDFFEEGLTVESIGLDKLDLEKYLK"
     gene            21451..21873
                     /locus_tag="RPH49_000568"
                     /pseudo
     CDS             21451..21873
                     /locus_tag="RPH49_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501036.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4870 domain-containing protein"
     gene            22110..22610
                     /locus_tag="RPH49_000569"
     CDS             22110..22610
                     /locus_tag="RPH49_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5123759.1"
                     /translation="MKKLVTATTLTAGIGTALVGHAQHADAAENYTNYNNYNYNTTQT
                     TTTTTTTTTTSSISHSGNLYTAGQCTWYVYDKVGGEIGSTWGNANNWAAAAQGAGFTV
                     NHTPSKGAILQSSEGPFGHVAYVESVNSDGSVTISEMNYSGGPFSVSSRTISASEAGN
                     YNYIHI"
     gene            22973..23926
                     /locus_tag="RPH49_000570"
     CDS             22973..23926
                     /locus_tag="RPH49_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacid dehydrogenase family protein"
                     /protein_id="HDY5123760.1"
                     /translation="MEKVYVAGAIPEVGLKLLQEHFEVEMYEGKGLVDKDTLIKGVKD
                     ATALISLLSTNVDKDVIDAGKDLKIIANYGAGFNNIDIEYAREKSIDVTNTPKASTNA
                     TADLTIGLVLAVARRIVEGDQLSRTTGFDGWAPLFFRGREVSGKTIGIIGLGEIGSAV
                     ARRARAFDMDVLYTGPNRKEEKEREIGAKYVDLDTLLKNADFITINAAYNPKMHHLID
                     TEQFKMMKSTAYLINASRGPIVHEQALVQALKDNEIEGAALDVYEFEPDITDDLKSLN
                     NVVLTPHIGNATFEARDMMSKIVANAAISAVQGEKPQFVVN"
     gene            complement(24018..25142)
                     /locus_tag="RPH49_000571"
     CDS             complement(24018..25142)
                     /locus_tag="RPH49_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent monooxygenase"
                     /protein_id="HDY5123761.1"
                     /translation="MKIAIIGAGIGGLTAAALLQEQGHTIKVFEKNESVKEIGAGIGI
                     GDNVLKKLGNHDLAKGIKNAGQILSTMTVLDDKDRLLTTVKLKSNTLNVTLPRQTLID
                     IIKSYVKDDTIFTNHEVTHIDNETDKVTIHFAEQESEAFDLCIGADGIHSKVRQSVNA
                     DSKVLYQGYTCFRGLIDDIDLKHPDCAKEYWGRKGRVGIVPLLNNQAYWFITINSKEN
                     NHKYSSFGKPHLQAYFNHYPNEVREILDKQSETGILLHNIYDLKPLKSFVYGRTILLG
                     DAAHATTPNMGQGAGQAMEDAIVLVNCFNAYDFEKALQRYDKIRVKHTAKVIKRSRKI
                     GKIAQYRSRLVVAVRNRIMKMMPNALAAGQTKFLYKSKEK"
     gene            complement(25453..26229)
                     /locus_tag="RPH49_000572"
     CDS             complement(25453..26229)
                     /locus_tag="RPH49_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDY5123762.1"
                     /translation="MKKNFKLRISTLLLIVILVVFAVLLIVNETKLFKNDVNYSFDEA
                     VSMQQGKGIVQTKEEDGKFVEANNNEIAKAMTISHKDNDMKYMDITEKVPMSESEVNQ
                     LLKGKGILENRGKVFLEAQEKYEVNVIYLVSHALVETGNGKSELAKGIKDGKKRYYNF
                     FGIGAFDSSAVRSGKSYAEKEQWTSPDKAIIGGAKFIRNEYFENNQLNLYQMRWNPEN
                     PAQHQYASDIRWADKIAQLMDKCYKQFGIKKDDIRQIYYK"
     gene            complement(26251..26484)
                     /locus_tag="RPH49_000573"
     CDS             complement(26251..26484)
                     /locus_tag="RPH49_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123763.1"
                     /translation="MLKTSAVISNTLLVIGLVCLFMMKLVLAITFFAVSLSISLVVFN
                     MMFRDRTTMKVIVNASFLIVILAIVVAYFLLSK"
     gene            complement(26711..27184)
                     /locus_tag="RPH49_000574"
     CDS             complement(26711..27184)
                     /locus_tag="RPH49_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1641 domain-containing protein"
                     /protein_id="HDY5123764.1"
                     /translation="MAERISSKIRRLEKSEEQIKLESLNEVTEAIAANKDSILKAIKL
                     IKVLDDAKILDALNGAVRGRQVIINKFAVELNKDIYTGLLTNMASMVFLLGELNVSDL
                     SDFLNKVNKGLHVANQASPNAKTSVRSLLGVLKDDDMNRSLTYMLNMLKGMSRED"
     gene            complement(27184..30138)
                     /gene="fdhF"
                     /locus_tag="RPH49_000575"
     CDS             complement(27184..30138)
                     /gene="fdhF"
                     /locus_tag="RPH49_000575"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDY5123765.1"
                     /translation="MQEHLVVTLDGKDYLVEPGTNLLEFIKSQDTFVPSICYNESMGP
                     IQTCDTCTVEIDGKIERSCSTVIDRPMTVNTVNNDVKDAQKEALDRILEKHMLYCTVC
                     DYNNGDCEIHNTMDAWGLQHQTYEYKEKPYEKDYGPFYRYDPNQCILCGRCVEACQDI
                     EVNETIRIDWDREHPRVIWDNDVPINESSCVSCGQCATVCPCNAMMEVNMEGNAGYMT
                     DTEPGSLAAMIDLTKKAEPGYGPLFAISDSEAEMRKERIKKTKTVCTYCGVGCSFEVW
                     TKDREILKVQPSHDSPANKIATCVKGKFSWGHINSDQRLTKPLVRKNGEFHEVEWDEA
                     LNVIADNFTSIKEKYGPDALSFISSSKATNEESYLMQKLARQVIGTNNVDNCSRYCQA
                     PATKGLFRTVGHGGDSGSIEDLEKAAMSVLIGTNTAEAHPVIASRMKRAQKLFGQKIH
                     VFDIRKHEMAERADRFYQPKPGTDLAWLSAVTKYIIDHDLHDKAFIEEWVEDFDEYYK
                     SLETFTMAFAEEATGIPEAELIKFAEECAKAESVVICWAMGITQQDIGSDSSTAISNL
                     LLVTGNYRRPGTGAYPLRGHNNVQGCSDMGSMPDKITGYQSIEADDIRAKFEKEYGVK
                     LNPKVGKDNHEMVEGVHDGDIHSLYLYGEDTGIVDSNINFVQAAFEKLDFMVVQDEFL
                     TFTATFADVVLPASPSLEKDGTFTNTERRIQRLYQALKPLGDSKPDWKIFQAIANKLG
                     FDWNYKHPSEIMDEIARLTPLYAGVSYDRLEGFNSLQWPVHPDGTDEPILYLEGFNFD
                     NGKAKLFPLSFDNYFKQDEVYDIHVNNGRLLEHFHEGNMTYQTPMLKYKVPRAFVEIS
                     PELAEDRGIHEGAEVKLISETGEAVLQVHVTDRVKGKEIYIPLNNDAMENGDLGAINL
                     LTNSDVDQYTDTPSYKRTSCRLEVITKRGKSPLNPNNFRVNKKRHPQYSVQVQKKWER
                     PDYVFPGNQVDK"
     gene            complement(30741..31688)
                     /locus_tag="RPH49_000576"
     CDS             complement(30741..31688)
                     /locus_tag="RPH49_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDY5123766.1"
                     /translation="MKRSSKSKMSLPKKIFLWVFGILVILAIVAVVYVAAKIFITGNK
                     IHNPLDRNHSELRDKKVSLNDGDPFTIALFGVDSDADRKKKGGGERSDSIMILSINPK
                     TKKTEIVSIPRDTRAEIVGRGTTEKIAHAYAYGGPNMAVKSLEKLMNVPIDHYATIDM
                     DGLHNMIDSIGGVDVVSNDTFTVDGVRFTKGQQTHVNGDQALKFIRSRKEEGAGGDFG
                     RQQRQQIVLEAMANKIASPSSITHFNSLMNEIQNNVKTDLTLGDLNTIRSNYKDANDT
                     INKHQLSGQGGIQSDGLYYFIPSEQSKAESTKLLKDNLE"
     gene            complement(31821..32618)
                     /locus_tag="RPH49_000577"
     CDS             complement(31821..32618)
                     /locus_tag="RPH49_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HDY5123767.1"
                     /translation="MTDKTLQQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVT
                     NVDKQIQQQFQQFLATHFPEHQLLAEEKSNKMITNEINHLWIMDPIDGTANLVKQQEE
                     YCIILAYFYEGKPMLSYVYDYPHKKLYKALRGEGAFCNGIKMEEPPSLKLEDAIISFN
                     AQVMNLDTVQDLFDASFSYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAE
                     LLNLKMTTLDGKAIDHLKGAPFIISNQACHETVLKILNANGGYQKYR"
     gene            33003..33695
                     /locus_tag="RPH49_000578"
     CDS             33003..33695
                     /locus_tag="RPH49_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YafY family transcriptional regulator"
                     /protein_id="HDY5123768.1"
                     /translation="MNKAERQNLIITAIQQNKKMTALELAKYCNVSKRTILRDIDDLE
                     NQGVKIYAHYGKNGGYQIQQAQSKIALNLSETQLSALFLVLNESQSYSTLPYKSEINA
                     IIKQCLSLPQTRLRKLLKRMDFYIKFDDTQHMTLPMLFSDILIYCTERNVMLVDHRVD
                     DNIKAENVIFIGLLCKHGHWHAVIYDIAQDKTAELEIENIIDISYSFGKTIQTRDISI
                     DNYHQFLNPIDS"
     gene            complement(33720..34457)
                     /gene="sdpB"
                     /locus_tag="RPH49_000579"
     CDS             complement(33720..34457)
                     /gene="sdpB"
                     /locus_tag="RPH49_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpB"
                     /protein_id="HDY5123769.1"
                     /translation="MENEKKKYTFKDIAWRDLLIIPIIGVIFYALTIAAYIGPILFGY
                     YKIDSNLIFVATITQALAYTIGIGAFYLFHLKVMPSRLRAGFAYIKKYWLRLSITYII
                     ALILIYTYEYMTQFLPKHLQYSETANELELNKMFEVPAFLPVAFLLIVIVGPIVEEIV
                     FRHILIGELGKKFNFIAMSIVSVFLFAFIHVTDAKSPFEFGPYLILSIILVFTYIKSG
                     RNLGSTIALHIANNFVSFVISVISIYA"
     gene            34506..34835
                     /locus_tag="RPH49_000580"
     CDS             34506..34835
                     /locus_tag="RPH49_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123770.1"
                     /translation="MINETKYMRQQITNLIQIIDTIKYNTLMTNWNIQTHIYKFNQIV
                     TNELNKFKGFETSYIINEKQVFYYEIITLLNKRPLRQVDYGNKIQYLNFYHTELSNAL
                     FAIKFAH"
     gene            35280..36152
                     /locus_tag="RPH49_000581"
     CDS             35280..36152
                     /locus_tag="RPH49_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDY5123771.1"
                     /translation="MSNVLTEIDSQYPYMTKNEKKIAKFILNSPQKVIKMRSQDLASL
                     LDISTSSVIRFSKKITDGGFHDLKINISKYVPKASSIYNVELMNNESTESLRTKLHTR
                     TTRALNHANNELNDKTIDQICHCLKRSETIFIYGFGASFVVATDLYQKLSRIGLNIQL
                     VQETHIFATLLATHNSNDSVILITNNGTQSEMQSMVKVIDDYHIPIITITSTRDNPVA
                     QASNIVLTYGKTDENEMHMGATTSLFAQMFTIDILYYRYVALNYHASLDFITQSKMAL
                     DNYRKHLSNINFKH"
     gene            complement(36541..37920)
                     /locus_tag="RPH49_000582"
     CDS             complement(36541..37920)
                     /locus_tag="RPH49_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5123772.1"
                     /translation="MENNELQRGLSARQIQMIALGGTIGVGLFMGATSTIKWTGPSVI
                     LAYLIAGIFLFLIMRAMGEMIYLNPTTGSFATFASDYIHPAAGYMTAWSNIFQWIVVG
                     MSEVIAVGEYMKFWFPELPTWIPGIIAILLLMAANLFSVKAFGEFEFWFALIKVVTII
                     LMIIAGFGLIFFGFGNGGHAVGISNLWTNGGFMPNGIVGFFFALSIVIGSYQGVELIG
                     ITAGETKDPQKNIVKAVNGVIWRILIFYLGAIFVIVSVYPWNQLGDIGSPFVATFAKI
                     GITFAAGLINFVVLTAAMSGCNSGIFSASRMIYTLAHKGEMPKIFTKIMRNGVPLYTV
                     VAVSLGILIGALLNVILPLYIDGAKSIFVYVYSASILPGMIPWFMILFSHLRFRKLHP
                     EEVEGHPFKMPGGAVTNYLTILFLILVLVGMVFNVETRISVLIGVIFLTIVTIYYFIR
                     YNKNNVKAK"
     gene            38200..38556
                     /locus_tag="RPH49_000583"
     CDS             38200..38556
                     /locus_tag="RPH49_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123773.1"
                     /translation="MLKQILPRATKISILFAVAFFIINYIGMEKPDILYLVGRTIIAT
                     LVFILICLTLFTIINSPERKIKLGTTLPIALIIGIIFGAIFLTVQIGVITGLIIGVIA
                     TFIWELIEKNKGGRSS"
     gene            38553..38738
                     /locus_tag="RPH49_000584"
     CDS             38553..38738
                     /locus_tag="RPH49_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123774.1"
                     /translation="MTTALIGVIVLILLIISFVPNYRAMKSAKEQGSNATRATIMVGI
                     DIILIVLIIVTLLLKYM"
     gene            complement(38834..39025)
                     /locus_tag="RPH49_000585"
     CDS             complement(38834..39025)
                     /locus_tag="RPH49_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123775.1"
                     /translation="MMGYIILFFLAGPVILGVGNLVIGPIFNKQTPFHVQVRSFVVGS
                     MIYLILATIGYFLLLQGKL"
     gene            complement(39036..39671)
                     /locus_tag="RPH49_000586"
     CDS             complement(39036..39671)
                     /locus_tag="RPH49_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5123776.1"
                     /translation="MYRAVIFDFDGTIIDTEQHLFNVINKHLEMHNADPISIDFYRSS
                     IGGAATDLHDHLIKAIGSENKDKLYEEHHLTSTTLPMIDTIKSLMAFLKQRHIPMAIA
                     TSSVKAEIMPTFKALGLDDYIEVVVGREDVEQVKPDPELYLSAVQQLNYMPTQCLAIE
                     DSVNGATAAIAAGLDVIVNTNKMTSAQDFSNVDYVAKDIDYDQIVARFFTK"
     gene            complement(39746..40663)
                     /locus_tag="RPH49_000587"
     CDS             complement(39746..40663)
                     /locus_tag="RPH49_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter family protein"
                     /protein_id="HDY5123777.1"
                     /translation="MFQKLSIFATKSFLVWMLVAAVIGFIFPQHVATLGKWVPYLLGI
                     VMLGMGLTITPNDFKMVFKAPRAVIIGVCLQFSIMPTLAFIIAKSFHLPPDIAVGVIL
                     VGCCPGGTSSNVMSYLAKANVALSVSITTVSTLLAPFVTPALIYLFANEWLEVSFLSM
                     LWSVVQVVLIPIALGIVLQIINRKIAEKASTALPIISVVAISLILAIVVGGSKHQILT
                     TGLLIFLVVILHNVLGYTIGYWLARLLKLDRQDQKAVSIEVGMQNSGLAVSLAALHFN
                     PIAAVPGAVFSFIHNITGPILAKYWSKKL"
     gene            40931..41461
                     /locus_tag="RPH49_000588"
     CDS             40931..41461
                     /locus_tag="RPH49_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123778.1"
                     /translation="MLIDKFETYIINIAGLNDRTTRKKLSKLCKSVQFCDALQFSINK
                     QFNQYVLEISLPKQQLPYFISFLSFHQYSIFQVLSPKKINELLDSDNLYQSAKRFDIN
                     IDGLQDAFIKDKVIDIMNMFQNHTDITYTLNKSHAHIICTPEIFAKLLHTIATRNIDI
                     LSANYRSSSMSKARIS"
     gene            complement(41527..43131)
                     /locus_tag="RPH49_000589"
     CDS             complement(41527..43131)
                     /locus_tag="RPH49_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDY5123779.1"
                     /translation="MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGSLADQH
                     TFWFKFWSVIESGGWVIFTHMEVVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINA
                     ILTQWPHTFGANLEKGVENVPGLKSIAGIATLDTNILGGIIISAIITWIHNRYYSKRL
                     PEMVGVFQGLTFVVTISFFVMLPLAAITCVIWPTVQHGIGSMQHFIIASGYIGVWLYH
                     FLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNEFAKSTKPLKEQFPYGFML
                     QGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVVGITEPLEFTFLFIAPY
                     LFVLHAVLAASMDTLMYAFGVVGNMGGGLLDFISTNWLPLGKEHWGTYVAQVIIGLIF
                     VAIYFFLFRFLILKFDIPLPGRKKTEEEVKLFSKQDYKNKKGDSVDSKRASTGNEYED
                     KAAYYLDGLGGKENIKDVTNCTTRLRLTVYDESKVADTEYFTHQQMAHGLVKSGKSIQ
                     VVVGMTVPQVREAFEQMVEDQSSEDK"
     gene            43461..44225
                     /locus_tag="RPH49_000590"
     CDS             43461..44225
                     /locus_tag="RPH49_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDY5123780.1"
                     /translation="MFLDEHINRNFDKLNDNDLHIAHFINTHIDECKNMKIQDLAQFT
                     HASNATIHRFTRKLGFDGYSDFKSYLKFESNKTHQLPSNSIDSFKQEIDSTFSYLERV
                     DYQLLTEKMHTASTIYLYGTGRAQLNVASEAQRILLTLHNHVIVLHDEHELKMILNKS
                     EPNDLFFIISLSGETHELLEVTNLLQLRQKYFISVTTMKDNTLAQKANYNVYVSSNTF
                     YLTDGTDYSSFISYHIFFETLVRKYNEYLLHNDISN"
     gene            complement(44283..44789)
                     /locus_tag="RPH49_000591"
     CDS             complement(44283..44789)
                     /locus_tag="RPH49_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC domain-containing protein"
                     /protein_id="HDY5123781.1"
                     /translation="MAKFNVENEHVEVEIEKLYKFSPELVYEAWTKKDLLKQWFMTSA
                     RTNKEIEADVKEGGKYRIVDQQRNGKVNVIEGIYESLVMDEYVKMTIGMPGLSETQDV
                     IEVEFFERETGGTQMLFYYRSLVEKERRFTNLEYKQKKKEYHDAMVHGFELMFDKMYH
                     VIETSTQQ"
     gene            complement(44956..46269)
                     /locus_tag="RPH49_000592"
     CDS             complement(44956..46269)
                     /locus_tag="RPH49_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC family protein"
                     /protein_id="HDY5123782.1"
                     /translation="MEVHKKSNAWALFPLLLFVALFLGVGIITGDFTSMPLNVAITIT
                     VIVALLMNRKESFAKKVEVFTKGAGHSNIILMMLIFILAGAFSNTAEKMGGVKSTVNL
                     GLSLIPENLIIVGLFVICMFVSISMGTSVGTVAAIAPVGYGFAQATDVPTALAMATVV
                     GGAMFGDNLSMISDTTIAAVRTQHTKMKDKFRVNFKIVLPGAILTIIILYFLTNGISL
                     NHAKNYDYNLIKVVPYILVLVLALLGVNVIIVLIGGTLLAGIIGLIDGSFGWMGLLDA
                     VSKGIISMEDIAMIALLIGGLVGIIQHNGGIEWLLQFVRSKVKSKRGAELGIASLVSV
                     ADIATANNTISIIMSGPLAKNIADEYDVDSRKSASILDIFGGCFQGLLPYSPQVISAA
                     GVAGISPLMLFPYSIYPILLGVCGLVAILFNFPKLKKNTSQEMKH"
     regulatory      complement(46346..46441)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(46494..47066)
                     /locus_tag="RPH49_000593"
     CDS             complement(46494..47066)
                     /locus_tag="RPH49_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123783.1"
                     /translation="MALIVSRAILFLILVLAFGIATVFPEQKLPVYILFTLFVVVAIV
                     SNVWLTHQNVKKHIIKFDKRVAYFLGVLSGVFYIGIVIYGSTIIGYYNFISFIIFAIS
                     IVLVQILENILGINFKNTLPSNKQLKVISKQRVQQFKVISLILVSVSIVFIFIALMLK
                     WWLLLVISIIVLIIITVAMIVYEKYYTTPD"
     gene            complement(47553..48434)
                     /locus_tag="RPH49_000594"
     CDS             complement(47553..48434)
                     /locus_tag="RPH49_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5123784.1"
                     /translation="MAAQDPRTKFKTTDYEKQEQEVPGLQSEMTPAPDCGETSYQGHQ
                     RLEGYKMLVTGGDSAIGRAAAIAYAKEGADVAINYLPSEEQDAQEVRQVIEESGQKAV
                     LIPGDIRDEQFNYDLVEHAYQQLGGLDNVTLVAGHQQYHDDIHGFTTEAFTETFETNV
                     YPLFWTVQKALEYLKPGASITTTSSVQGYNPSPILHDYAASKAAIISLTKSFSEELGP
                     KGIRVNCVAPGPFWSPLQISGGQPQSKIPTFGQKTPLGRAGQPVELCGTYVLLASEES
                     SYTTGQVFGVSGGVQID"
     gene            complement(48543..49664)
                     /locus_tag="RPH49_000595"
     CDS             complement(48543..49664)
                     /locus_tag="RPH49_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="HDY5123785.1"
                     /translation="MGLKDQAVAWRRYFHQFPELSDKEFKTTQKIKDILTEHHIRILD
                     LPLATGLVAEVGQGPSCIAVRADIDALPIQELVEQDFKSKNEGVMHACGHDIHMASIL
                     ATAVKLKEIEGTLTGRVKFIFQPAEELGHGAFKIIETHALKDVQAVLGFHNDPSRSVG
                     TFAIKTGAITSAVDRFEFHIKGVGGHAAKPEQCNDPVIVLAQLINSIQSIVSRNLSAF
                     EEAVVTIGQISCGNTWNVIADHAYVQGTVRSFDPVVRKLVETRLQNIADGLAQAYNMK
                     INLNYTHLPGAVMNDEVLTHKAIAVAQHVGYKMEMMEQPLTIGEDFSGYSQHFPSVFA
                     LIGSHSEYDLHHPQYKPDERILEKVPEYFVEFVKRLLHE"
     gene            complement(49939..51177)
                     /locus_tag="RPH49_000596"
     CDS             complement(49939..51177)
                     /locus_tag="RPH49_000596"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HDY5123786.1"
                     /translation="MNDLIINHIAELILPKSTDKPLKGKELDELNVVKNGTVVIKDGK
                     IVYAGTHTDDYDATETIDASGKVVSPALVDAHTHLTFGGSREHEMSLKRQGKSYLEIL
                     EMGGGILSTVNATRETSEDDLFKKAEHDLLTMIKHGVLAVESKSGYGLDRENELKQLK
                     VSNRLAEKYDLDMKHTFLGPHAVPKEASSNEAFLEEMIALLPEVKQYADFADIFCETG
                     VFTIEQSQHYMQKAKEAGFKVKIHADEIDPLGGLELAIDEQAISADHLVASSDKGKEK
                     LRNSDTVAVLLPATTFYLGKEDYADARGMLDNNGAIALATDYNPGSSVTNNLQLVMAI
                     AALKLKLSPNEVWNAVTVNAAKAIDINAGTINTGDKANLVIWDAPNHEYIPYHFGINH
                     AEKVIKNGKVIVDNTLSFKA"
     gene            complement(51177..52838)
                     /gene="hutU"
                     /locus_tag="RPH49_000597"
     CDS             complement(51177..52838)
                     /gene="hutU"
                     /locus_tag="RPH49_000597"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HDY5123787.1"
                     /translation="MRKIQAKKGLSIECKGWEQEAVLRMLYNNLDPEVAERPEDLVVY
                     GGIGKAARNWEAFEAIEKTLRELESDETMLVQSGKPVAVFKTHEEAPRVLISNSVLVP
                     EWANWDHFNELDKKGLIMYGQMTAGSWIYIGSQGIVQGTYETFAELGNQHFNGDLAGT
                     VTLTAGLGGMGGAQPLAITMNHGVAICVDVDETRVDKRIDTKYCDVKTADLDEALKLA
                     EEAKERGEGLSIGLVGNAVDIHQAILEKGFKIDIITDQTSAHDPLNGYVPQGYSVEEA
                     KVLREKDPKKYVELSQASMAKHVELMLEFQKRGAVAFDYGNNIRQVAFNNGVKNAFDF
                     PGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPENEKLLRWLDLAEEK
                     ISYQGLPSRIAWLGYGERAKMGLALNRLVRDGEISAPIVIGRDHLDAGSVASPNRETE
                     SMKDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGSERAER
                     RLERVLTTDPGMGVARHVDAGYDIAIQTAKEKGIHIPMIDKAGDK"
     gene            52998..>53875
                     /locus_tag="RPH49_000598"
     CDS             52998..>53875
                     /locus_tag="RPH49_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5123788.1"
                     /translation="MKIIQLEYFLAIVKYNSFTKAAQFLHISQPSLTATIKKMEADLG
                     YDLFTRSTKDIKITEKGIQFYRYASELVQQYRSTMEKMYDLSVTSEPRIKIGTLESTN
                     QWIANLIRKHHSDYPEQQYRLYEIHDKHQSIEQLLNFNIHLAITNEKITHEDIRSIPL
                     YEESYILLAPKETFKNQNWVDVENLPLILPNKNSQVRKHLDDYFNRRNIRPNVVVETD
                     RFESAVGFVHLGLGYAIIPRFYYQSFHTSNLEYKKIRPNLGRKIYINYHKKRKHSEQV
                     HTFVQQCQDYLYGLLEA"
BASE COUNT        17961 a        10029 c         7538 g        18347 t
ORIGIN      
        1 aattgagctg ctagtgtgcc tttttctaaa tccaatcaaa ttctaaataa ttgctcgcta
       61 ttaattttta tcaatcaaat ttcaaactta agcaaatatg ttaaaatttt aagcaaatta
      121 ctttaaaata aagttcaagc taattaaagg ggttagataa tgaacaaaga tgtatcttta
      181 ggtcaaccaa ttgttagata tgaagatgga aaattattca atacgacaga tcaatatgtg
      241 acagaatttc cacttacaat tatggtgaat ggtgaagaat ttgcgactgt tatatgcagt
      301 ccaacaaacc ttgaggagtt agtcattgga tttctggctt cggaaggtgc cattttaaag
      361 cgagatgaat taaaatctgt actaattgat gacagtaaag gatttgccca tgttgaactt
      421 aataaagatt taggcgatcg ctttcaatat tccacaaaac gaatgattgc atcttgttgt
      481 ggaaagagtc gtgagtttta ttttcaaaat gatgctgcta tcgctaaaac atctatgtct
      541 aaaatcactt taactccaat acaaattatt aacatgatga ctcgattaca aagtgcaagt
      601 catatttacc aagaaacagg tggcctgcat aatgctgcta taagcgatgg tttgacattt
      661 tttgtacatc gacaagacat tggtagacat aacgctctag ataaattata tggattttgt
      721 attcagcgac atattactgt ccgagataaa gtattaattt tcagtggacg tatttcatca
      781 gaaattttaa ttaaagccgc gaaaattggt gttggcgtca ttttatctaa atcggctcca
      841 acaacgcttg ctgtaacttt agctaatgac ctaaacatta cgtcagttgg atttattcga
      901 aatggtggct ttaatatata cagtcatcca gaacgtatca ttgattctga acaataacat
      961 atttattata gtgtgtcata atgaacgata ttctacatga atcaacaacc ttaaaacaac
     1021 attgtttaat atacttatca caacttaaaa agcagtaagt cgatttctac tcgaaaccag
     1081 cttactgctt tttatatttt tcatttattc taatacaaac ctaccatcaa tcgttaattt
     1141 ccaatatctt cttttaatat ttgataacaa aacgattgat agacataacc ttgctttgca
     1201 tacatatctt ttgctgtatc ttcaccatct gccaccaata taaccggttt atgatctcta
     1261 gatatagcat attcacctac taatgactgc atggtagaac cgattccttg gtgtcgaaat
     1321 tgttctaata caccaaatcc atctaattca atgtaatttt cactttcaat gacatctaca
     1381 acgccaatag gttcattgtt taaataagct actaagcgtt taatcacatc tttttgataa
     1441 tgttccctta ccattttttc atgtgcatct gcatagtctt ttccaaatgg caaactaaat
     1501 tgatatgcaa cttttaaata ggcatctata tgcgactcgt caacgatggc aatttcaacg
     1561 tcagcgttac gcggcaaatt ggcaagggca tcactttcta tggcatacaa ttccataata
     1621 cctagttcaa aattcatatc tttaaacata gccatccaat gattatcaag ttgttcattt
     1681 tctgggaaac taaacgcata atgatttgaa ccttgatttg tatgtaattg atgttgacgt
     1741 tctaagtctt tcagccatcg ctcttcggta ggcatctttt tatatatcca tgtgttgctt
     1801 gtatatcgtt gtggaaaaga aggtgttaaa taaatcaact gctcatcgtc attttcaaat
     1861 atagtgccgt tacaatatat atctgacata cttatactag ccattgacac ctactccttt
     1921 cacttttata aatttcaaag caacttattc aattacttta ctatcttaaa tatgattttt
     1981 ttaatcccat aatttgacga aactgcgagt gattaagtaa agctgtacca atcaaacttg
     2041 ctacaattgc ttttaatata tcaccaggca aataagctaa tgaaattgaa atagctttcg
     2101 taaatggtat gttaataatc atgcccataa tcaatgtacc aataacatct aatgctataa
     2161 caccaaaaac taaaataccc acgaataaaa tccagaaatt aatttcattg atgaatctat
     2221 cacgaatcgc accaatcatg aatgctacaa ctggatataa tagtaaaaat cctgctgaag
     2281 gacctgcgaa tacaccaatg ccaccgcgac cgcctgataa aagtggcaag ccagcaacta
     2341 ctaataataa aaagacgata acacttaatg tgccatattt acgtcctaaa atcacacctg
     2401 ctaagaaaat accaatgttt tgaagtacaa ttggtactga agaaaatggt agtggaatta
     2461 ctggtaccaa tcctaaaata gcgataatcg ctgtcattaa agctgtatat actaactgtt
     2521 ttgttgtcat tttttacttc ctttcgtatt tcatgaccat tattatagca ccattgtaaa
     2581 ctttaagaaa cgaaaagttt acaataagct gttctatata aattaaaacc ttaattattc
     2641 tacacagctg ttaatttact tttttagcaa gtgcagttat ataatcaaaa aatgcgttgt
     2701 tatctacatg atttatgaca ttaattttgc gcccatcttt acactcaaat gtcttacctt
     2761 gacttggtcc ataacttatt acatccactt ttttctcaat tgaatgaact aagtccttgt
     2821 taccaatata agcagtcgtt aaaacatccc ataaaaagta agtagaattt gttataaagt
     2881 gtgttaatgg tggtaccgct gcataactta ctcctaaaaa atcaatgccc gtatattggc
     2941 gttcattcgc ccatctttgt ctaacatcta acgttagcgg cacttgattc gtactttcta
     3001 aagcaaccat atcaatctct atatcgctat caaaaacaat tttaaccgct tctggatccc
     3061 aatatgcatt ccattctgca gaaccatcat gctcaggttc ttcaacattt ccttttggta
     3121 aaaaggtacc acccatccaa actaattttt ctatatactg aacgatagat gaatcttttt
     3181 gtagtgcttt tgctaaatct gtaagcgggc ctgtaaataa taatgttact ttttctgatt
     3241 gtctctttaa agtttgaata atgtcttcaa aggcttcttt gtcgctcaca tttgaagcaa
     3301 cgtgtttgac tggctcattt aaaattggca atgcgtccat aaaaaaggca tgcatacgcc
     3361 attctttagg aaatggattt ttctctcgtt catatgatgg ggaaacttga atatcttcat
     3421 ttgaaaaacg gttaataatt tttactgatg cgctcaaaga tggctctaaa taacaatcag
     3481 caccaattgt actgacccct atcaattgaa cgttttccat ttgtaataat aaaaatagag
     3541 atactaaatc atctacacca ccatcatggt taaaataaac tttcttagtc actcgaaatc
     3601 ccccttacat ttcattttcc attaacaata ttatgttttt ataaaacgtt gttatatatc
     3661 tttctacaaa atcataacat tctgttgtaa tccttttaaa cctcttcttt aattgataat
     3721 cattccctga tatgccttcc ataaagtatg cactaaaata attatgatat aacttattaa
     3781 tgaagagata cattgagcta tttctcaggt atactacttt agctgtaata atactaatct
     3841 atcattaatt aaattgaatg ataacaacgg cacttattat tttaaaaaat acaaatatct
     3901 aactttctag ctataaaaac aagagcctaa tacaatatca aaagattgat atgtttcaga
     3961 ctctcatttc actaacttat atagttgaat tattttgcag ctttaattaa tttttctttt
     4021 aaatctttac gcatgaaatc taatgtataa ggatcgttgt accagtatgt accagcatca
     4081 actttaacaa tatgtccttc tttagtagct ttcaaattct tccacatgtt tgttgattca
     4141 tatcctggtg taggtttacc ttcacttgta ctcacaatgt aatcaccagc atatttttca
     4201 atttcttctt gtttcacttc agcccaacct gcttttgcag ttaacttttg ttgttctggt
     4261 tgcattttta aaccaaatgc ttgatataat acttctccac cacgacccca gttatcgccg
     4321 taagtgtata attttttatc aaattcatca aacaatgaca ctgttgcatc ttgtccaatt
     4381 gcttttttaa tttctttacc gtctttagca gttgtttctt cccaatcttt cttccaagct
     4441 tttactttat cttctttacc aacaattttc cctaacattt cttgttgttc taaatattta
     4501 tgcttattat agtcaacaac tactgttggt gctacttttt gatatttttt aatgtctttg
     4561 tcagtagagt atacaataat taaatctggc ttttctttag caactttttc tacatcgcca
     4621 tcaccaattt ttgtaacacc tttaaattta tcttttaata ctttgctttg atcgacttgt
     4681 tgatttacag ctacaatgtt tgcacctaat tttttaagtc caccagcata tgttggcgca
     4741 actactgcaa tgcgtttagg gtctttcgga atatctaccg ttttgccatc gtccatttta
     4801 taagatttag tttcagcttt gttatttttt tctccttggt tcccacacgc agctaacact
     4861 aataacataa ttattaatgg taataatagt tttttcataa tttcctccta ttgaaaatga
     4921 ttatcaatca ttccaaaatt atacaagatt gcatatacat ttacaatagc tagtgttatt
     4981 tattttttta ttttcgcaaa aaatttagca aaatatctta atatacctat aaattcccac
     5041 aaaaaaggta aatccgaacg tcaaatttca tctctttatg ccattcaacg attgatttac
     5101 ctttttaaat ttaaaatgta tctgtaatac tcttagcaat atttgtatat gctgcatctt
     5161 ccataggtgg attgtgtaat cctgcacgca tgtcacgata gtaacgttgt aatggtcgat
     5221 tcatttctaa gcttttagca ccaacaatgc gcatcgctaa atcaatcact tcaaggcctt
     5281 ggttcattac cattacttta ctcgcactcg tcgcatttct aatctgactt tcgtctgtat
     5341 attgttgata gccttttgct gtactccata aaaattgtct cgcacataac aacagcgttt
     5401 ccattttccc taaattttgt tgcacagttg gcaatgttgc aatcgttcct tcaatactat
     5461 tagggctatg ttggattgca aagtctacag cataatttct agcagcttgt gctataccta
     5521 aataacagct tggtatatgc aatatccaac catttggcgc tttacttttc tctgtttcca
     5581 ctaaatgttt taatggtact tttacatcat ttaatattaa atcatgactt tctgtcgctc
     5641 gcatacctaa tacgtcccaa ttatcggcaa tttcaacacc aggcaaattc ctgtccacta
     5701 agaaaaaacc aacactttct aattcttcta tataagcagc aacaataata tgtgttagtg
     5761 ctttactcat tgatgtatat gtcttcacac catttaaaat atacccgtca tcagctttaa
     5821 cagcatgtgt acttggtctt ccccctcttg ttggactacc catttcagct tcactaactg
     5881 ctctattaac taatgcacca ttattaattt caacagcaaa ttgctccaac atatcttgag
     5941 accataattt ctgttcataa atttgtccta cgacactcac atgccaacca atagataatg
     6001 ctgtggcacc atcaagttcg cctaaaaatg attgcaaaat aaccatgtct tctatggtcg
     6061 caccttcacc accatattct tttggtaacg ttaattttcc ataaccttct ttaattaacc
     6121 attcaatatt tttatatgga aattggctat gttgatcatt atattcagct ttagccttaa
     6181 atgtatctcc aattactttg aatttttcaa tccattttct ttgaatttcc gttgttatta
     6241 aaaaggaatt atccatatca ttcatattag tcaccccaca caacacacaa tataaattat
     6301 ttattcctag tttaacactc gactttaaaa ataaaaagga acgtgctgtg aacaattaaa
     6361 agaaagttga taattcgatt aagtatccaa ttaattttct ccataaaaat acaccttaaa
     6421 ctatacaact cgctgtatgg tttaaggtga tattcaaaca atactaggtt tgatttaact
     6481 ttcaagcatc tactttgtca tgtttaatac cagcaaataa taaaatccaa gtcacaataa
     6541 taaatggcaa tgttaatgca ggtaagccaa acggttcaag caatgttgtt gtacctagtt
     6601 gcaccactac tgttaataac acacctaaaa aagtcgaaat ataaggatta atctctgttt
     6661 taaatgtaaa tcctagtgcg attgccatta atacaaagtt ataaccgaat aacccctgat
     6721 taatatcatc ataattacca cctaatagag ctacaatgat aaagcttaac aaactagcta
     6781 taacagctaa gagtgctgct tttcttgatg ctatcaatat gccgattaaa atacatacgc
     6841 caccaattac actcgcttcg ataaatactt gactgaatcc ttcaaataat gactgaatga
     6901 aatgtattct atcattgttg ctaaaattaa ccgtttcaat gttttgaggc attaacttta
     6961 aagatgtatc tacaaattta acctgtcctg atagtaaaat tgtaaaccaa gtcacaatga
     7021 caaaaggcat cgtcagcatc ggaactttat atggtcttaa aacttctctc actgcagcag
     7081 cgactggtaa cgttaataaa gttgctatca ttgttataac aatatctaat cctgacttat
     7141 ctaaaaagat tgttaacgca atggcagtta acactggatt aaatccggct aacccatcat
     7201 taatctctgc ttcactataa tttataaaac gcgcaaaagt ataggcgatg atgctaccta
     7261 caatagccgc taatccaatt gtccaatcag caacaaataa tcctattaag ataaataatc
     7321 ctgtccattt attactaatt aacacaacct gagaaatatt tttcaaaagt acatctatca
     7381 ttttcaaaat gcccaccctt tttcttgaat gtttactcat taatatacta ccattttaca
     7441 aaaagttata ttaaaaactc tattttctaa atcctaaata tcttttgcta tttgttgtaa
     7501 ttgtaatcat atatttttaa atacgaaata gtaaattaat tttttacttt tacgcattaa
     7561 actttgtata ttacttattt atcacaacaa ttaggattaa tataaatttt gtaaattgta
     7621 tctaatatga aattgggggt tttaatttgc attttacaca acgagagcaa gacaaattaa
     7681 tgattgtagt ggcagcggaa gttgcacgtc gtcgtaaagc acgtggtttg aaactaaatc
     7741 atcctgaggc attagcttta atcagcgatg aattattaga aggtgcacgc gatggtaaga
     7801 ccgttgcaga gttaatgagt tatggtagac aaattctaaa caaagaagat gtcatggatg
     7861 gtgtcgaaca catgattaca gatatcgaaa tcgaggctac gttccccgat ggtactaagt
     7921 taatcacagt acatcaccct attgtttaaa ggaggcagtc aaatgatacc aggagaaatt
     7981 attacaaaaa gtacagagat tgaaattaat aaccatcatc ctgaaacagt tatcgaagtt
     8041 gaaaatacag gagatcgacc aattcaagtg ggctcacatt ttcattttta tgaagcaaat
     8101 gcagcattag atttcgaacg tgaaatggca tatggaaaac atttagatat tccagctgga
     8161 gcagctgttc gatttgaacc tggggataaa aaagaagttc aattagttga atatgctggc
     8221 aaacgtaaaa tttttggttt tcgtggtatg gtcaatggtc ctatcgatga gtcacgtgtc
     8281 tatcgcccga ctgatgaaaa tgatgaatat gcaggtgtat tcggagataa cggtgctgaa
     8341 aacgtgaata aaaaaggagg aaaaagatca tgagctttaa aatgacgcaa aatcaatata
     8401 cgagcttata cggtcctact gttggagatt ctattcgttt aggtgatacg aacctatttg
     8461 ctcaaataga aaaagactat gcagtttatg gtgaagaagc tacctttggc ggtggaaaat
     8521 ctattagaga cggtatggcg caaaatcctc gtgtaacacg tgatgacgtg aacgttgcag
     8581 accttgttat ttctaatgcc gttattatcg attacgataa agtggttaaa gccgatatag
     8641 gtattaaaaa tggttatatt ttcgccattg gaaatgccgg caacccggat ataatggata
     8701 atgtcgacat tattatagga tcaacaacag atatcattgc cgctgaaggt aaaatcgtca
     8761 ctgctggtgg tattgatact catgttcatt ttattaatcc tgaacaagca gaggtcgcat
     8821 tagaaagtgg tattacgact catattggtg gtggtactgg tgcttcagaa ggttctaaag
     8881 caacaactgt aactccaggt ccatggcata ttcatagaat gttagaagct gccgaaggtt
     8941 taccgattaa tgtcggtttt acaggtaaag gacaagcaac aaatccaact gcactcattg
     9001 aacaaatcaa tgccggagca attggattaa aagtacatga agactggggt gcaacaccat
     9061 ctgctttgag tcatgcatta gatgttgctg atgaatttga tattcaaatt gcattacatg
     9121 cagatacttt aaatgaagca ggatttatgg aagacacaat ggctgctgtt aaagaccgtg
     9181 tacttcatat gtaccatact gaaggtgctg gtggcggtca tgcgcctgat ttaattaaat
     9241 ccgctgcatt ttcaaatatt ttaccttcat ctacaaatcc aacattgcca tatacacata
     9301 atactgtaga tgaacattta gatatggtaa tgattactca ccatttaaat gcggctattc
     9361 ctgaagatat cgcattcgca gattcacgta ttcgtaaaga aacgattgca gcagaagatg
     9421 tcctgcaaga tatgggtgta ttcagtatga ttagttccga ttcacaggca atgggccgtg
     9481 taggtgaagt aattacacga acatggcaag tagcacatcg catgaaagaa caacgtggtc
     9541 ctttagatgg tgattttgaa cataatgata ataatcgcat caaacgttat atcgctaaat
     9601 atacaattaa cccagcaatt acacatggta tttctgaata tgtaggatct atcgagccgg
     9661 gcaaactagc tgacattgtc ttatgggatc ccattttctt tggtgttaaa cctgaattag
     9721 ttgtaaaggg cggattaatt aactctgccg taaatggcga tgcaaatggt tctatcccta
     9781 catctgaacc aatgaagtac cgtaaaatgt atggtcaata cggcggaaac cttacaagta
     9841 cgtcaatgac attcgtgtct aaaactgctt atgaaaatgg tatcaatcgt gcattaaatt
     9901 taaaacgcat ggtgcgtcca gttaaaaata ttagacaatt atctaaagca gatatgaaaa
     9961 ataacagcgc aacacctaaa ttagacgttg atccacaaac atatgaagta tatgtagatg
    10021 gagaaaaaat tacaagtaat gcagcaactg agttaccatt aactcaaaga tacttcttat
    10081 tctaggagga acatagaatg attgttgaag aaatccaagg caatattgcc aatttgtcaa
    10141 attcagaaaa acaaaagcac gtcgaaaaag tataccttga aaattcagat ctcgttaaac
    10201 gtattcaaag agtcgttaca gaccatggca ctgaaatagg cattcgttta aaacaaccta
    10261 ttgacttaca atatggagat attttatacg cagatgacca taatatgatt attgtggatg
    10321 ttaattcaga agatctttta gtgattcaac caagaacatt gcaagaaatg ggagatatag
    10381 cccatcaatt aggaaatcgt catttgccag cacaatttac agagactgaa atgctagtac
    10441 aatatgatta tttagttgaa gatttattaa aaagtttagg catcccatat gttcgagaag
    10501 accgtaaagt taataaggct ttcagacata taggccattc tcatgattga tcatacacac
    10561 ttaagattat ttcagttctg tgattcacag tttccaacag gtgctttcag tcattcattt
    10621 ggtcttgaaa catatattca acgaaatata attcatgatg atcatacttt tattgcttgg
    10681 ttaaaaatgt ttttacaaga gcaacttacc tattctgatg gtttagccat gcgtttagtt
    10741 tatgatgcat tggaaaatga tgatacacaa aaagtattac acatagataa gctgatgttt
    10801 gttcaaaact tacctaaaga aacacgtgtt ggtgcaaaac aaatggggac tcgcatggtt
    10861 aaattggctt tagaacttta taatagccca tggattgctt ggtatcatca acaaatgcaa
    10921 gataagaaag caaagttaaa tccagctatt tgttttacta tgctaggcca ttatttaggt
    10981 gtagatattg aaacgattat tgattactat ttatatcaaa atgtttcaag tttaactcaa
    11041 aatgctgttc gtgctattcc acttggacaa actgctggtc aaaagatagt tactcacatg
    11101 attccttata tagaagaaac aagaaagcag attttcgaat taaaagaagc agattttggc
    11161 atgacagcgc ctggtttaga actaaatcaa atggcgcatg agaacgtcaa tgttagaatt
    11221 ttcatatcat aggaggttat aattgtggca aacccgatta aaattggtat tggtggtcct
    11281 gtaggtgcag gtaaaacaca attaattgaa aaagttgtaa aacgtctttc aaaagaaatg
    11341 agtatcggcg ttattacaaa tgatatatat acaaaagaag acgaaaagat attagtaaat
    11401 tcaggagttc tacctgaaag tcgtatcatt ggtgttgaaa ctggtggatg tcctcatact
    11461 gcgattcgtg aagatgcatc tatgaacttt gcagcaatag acgaattatt agaacgtcat
    11521 gacgatatag aactaatttt catagaatct ggtggcgata acttagcagc aacatttagt
    11581 ccagaacttg ttgacttttc aatttatatt atcgatgttg ctcaaggtga aaagattcca
    11641 cgtaaaggtg gtcaaggtat gattaagtca gatttctttg taattaacaa aactgattta
    11701 gctccctatg taggtgcatc attagaacaa atggctgaag atactaaagt atttcgtggt
    11761 aaacgtccat ttacttttac taacttaaaa actgacgaag gtttggatga agttatcgat
    11821 tggattgaac gcgacacttt actcaaagga ttatcataat ggatgaacaa caatggactg
    11881 ggcaacttga tttaacagtg tttttcgatg gcaatcgatc agtatcaaga gatattttct
    11941 ttgaaaaagc acttaaagtg atacgtccag tttatctaaa tcaatctacc attcctacat
    12001 tttatatagt aaatgtaggt ggtggctatt tagatggaga tcgttaccgt atgaatgtga
    12061 atgtcgaaga taacgctaaa gtgacattga catctcaagg tgcaacaaaa atatacaaga
    12121 caccttccaa tcatgttgag cagtatcaaa cttttaattt gaaagataac gcatatttag
    12181 aatatgtcgc tgatccaatc atcgcatatg aaaatgctaa attttatcaa cacaatacgt
    12241 tcaatctcaa taattctagt tcattatttt atactgatat tttaactcct ggttattcaa
    12301 aaactggcga agccttcaag tatcaatata tgcatttaat aaatgaaatt tatattgaag
    12361 atgagttagt cacatatgat aatttattat tgaatcctaa taaacaatcg atcaatgaaa
    12421 taggttatat ggaacattac tctcattatg gctctgctta cttcatacat gaagatgtta
    12481 accaaaaact aatcgattca gtttatgaaa ccattagttc ttatagcaat acattcgatt
    12541 gtcgtgttgc tatttctcaa ttgcctacac atggttttgc agttagaatt tttgcttatc
    12601 gcacacaaat tatagagaaa atacttggaa ccatccaaag ctatatcgca gaaaatattt
    12661 atgatcgtaa acttgatttt ctaagaaaat attaaaataa aaagactagt gtaccttgtt
    12721 tcaagcttaa taagctgaaa taaggtatgg ctagtcttta actttaatta aagcatcttc
    12781 aatatttaaa ttttaagtta attttatgtc ccaatgctga ataaataact tcgttttaat
    12841 aaattgttat cgttcaatgt tattaaacgc aattaacctt gatttaattt ttaatgtatt
    12901 cttctaattc tgaaatcagt ttttgaatat ttgctttttg tgtatctgta acataaacaa
    12961 taactgttct ttcgtcttgt aaacttcttt tctttgataa caattttaaa tcttttagct
    13021 tttgtaaagc tttagttaaa tagtaaggtt tgaactctga gcacttagca atctctttag
    13081 atgagatttc gttagactca cttcttaaaa tatgatttaa aatataaatt tcttcatagt
    13141 tcaaattgaa cttctttttt gtatctctga aaaacttctt aacttgaaat gttgcgttga
    13201 ctaaatcatt aatgtcatta attttactca ttattaaacc actcctctga tgcacatctt
    13261 gttgtagcaa ggttcacatg taatttatta aatcgaaact ctatccaact atgttataaa
    13321 gttcattcta aacaaataag tataaaaatt caatattttt attactagaa tatggttaaa
    13381 tacatttatt tcttacaata atttgatgtt taagatattt tgccaaattg aaaattatta
    13441 gtctgaatat tttgtatctt aactgatatg taaactttta aaattttaat ctatatcaac
    13501 gtgtctgatt tgatattttt tatattaatt tgatggcttg ctcacgaaat ttataaaata
    13561 taaaaaaaga agagctttaa atcataacgc atgccattta tctttaaatg caatgagtta
    13621 tcattcaaac tcttcttatc aacctacata cattgacatt atactatcat atgttgtttt
    13681 acatattcaa caaacatttc aacgttatca cttttaatat catgcattgg gacattacca
    13741 atattaaatt tgaacattat agtttgacca tcataatcta tcttctctat ttcattataa
    13801 ctaatacttc tataataaaa ttggccattc atatctacat tcataattaa tctttcattt
    13861 gttgctataa atgccccttc aaattcattc tcaccttgaa cttgatactc aattattcct
    13921 agcactgacg gacccttttt ttcagttgga aataaatcat ttggattcac attatctaaa
    13981 atcataatat ccctcccact taaaactata aactattctt cataggtata tgaaatacaa
    14041 gtgattaact atttattatt aagcttaact tgtattccct tttcaagata attataacat
    14101 gcttgaataa gcatagtgac tttagaaaac ttttctctct tgattgttac aataacacgc
    14161 ctttcatcta attcacatct ctctttttta actaatcctt tcaaaattaa acactttaaa
    14221 atcggactaa ccgcaaatat cgggtgatgg aattcaccct gtaattcttt aaccgtcaat
    14281 tgacctttat gcagatttaa tattcctaaa acgtataact cttctaatga taattgacac
    14341 atatttaaat aacactttag atttcgaaat aattcttgtg acgacaacaa atacgataca
    14401 tagtcacaac taaaatcaaa tgtatattga ccaaaataac gttcaatata gtcactaagc
    14461 tcattattca tatattctat tttatctata tgcattttat taatcgaaat agtcaattta
    14521 cgttgatccc tttgatctct tcctttcaat agccattgat gattgtttaa ataacttaac
    14581 atttgaagaa gtgccatctt agattggatt tctttcattt ttaataacct atctattgaa
    14641 gcgctattgg aatcagaatt atcatattta actaatagat ttaatagttt cacttgagtc
    14701 aaagtgagat gaaatgaata tttcaacata tcattaatga ctttcaacat tagtatgtgt
    14761 gcagttaaac gcttaacttt aaatttagac atctttaaaa cctctcttaa accatgccta
    14821 tatctcaaga tgatatttca aatgaacaat actattgctt gagaccatta atgaatgatc
    14881 ataaatattt ctttctataa aattagcttt ccaataactg tgttgttgca taatatcatt
    14941 cacaagtaca ccattttcgg aagtatgatt atctttatct atacttaaaa caatttgttt
    15001 agttttagca tggctaaatt gttgaagact cttacacgat aaacgtatag cgtctgaatt
    15061 ctcatttaac aatgcggctg gcaaacaaat gacacattgt acttcatgtt tgaacttcgt
    15121 tacaatcatc gtgtcatttt gataaataac aatccctcgt aattgattaa gtatatttat
    15181 gataaaaatg aatattgata atctagtcaa atttatttct ttgctcgctt cacttataat
    15241 tgacatgtgc ataataagcc ctcgaaattt tgtataattt gtcaaaagtt cagtaatctt
    15301 attaatatca gacattgtga ttttttcttt taagtcatca ttctcattaa tcaaatctac
    15361 atcacatata attttagaac gtgcaataga cacctgttct atttgtctta gcggtaagat
    15421 aaaatagtct attagatgat caatttcttt ataatagcgc acattcaact catttggttc
    15481 cagatgatat attaattcaa atactcctat ataattatct attaaacgtt tcagtttttg
    15541 aattgcagta gtatttaagt cgttaattaa aaatccaatc ttacatctat tactctcaaa
    15601 agtcatatta aaaattgtag ctactagctt ttctatcttg cctctttcag tactcgttaa
    15661 caattcctta tattcatgtt taatacgaaa tactacattt acattgtaat tcactatctt
    15721 ttgaagtaat aaagtgattt gttcaatcga tagctcatta cttgtgtcga ttgtaacaat
    15781 tatatgcaag ttttcaggat taacacttaa tctttgaatg atttgtttaa tagtataata
    15841 atccatccaa taaaaattac ttcctttaat atagatgttt ttaggttgat acatttgact
    15901 ccttttggta ggctcaaaag gtatatcaat ctcgcgcata cttgaagaac tttgattagt
    15961 atcatcaaat aattcaatta tatttttatc aatttcaact aattgggaat ggtaaattga
    16021 atgagatgtt ggactatatc tttttctaat taatttagga gtgtcaccat acgtttcttt
    16081 aaagaggtgt ataaaacgag aataatgatt aaaaccatga ctacttgcga tttcttcaat
    16141 gggcttctta gaagttaaaa tatcaattaa gcaatactcc agtctaatat gatttaaata
    16201 ttgaataaaa ttactataag gtgtcgcttt aaacatgtca cttaaagctt tgtttgtaat
    16261 actaacttga ttaatgacat ctttcctatt tatcttttta tggtggttgt ttgttaaata
    16321 atcgtgcact tcttcggcta ctaaatgacg actaccatcg tatgtattta atgacattaa
    16381 ttcaacacac atgtaattaa taatcttatc attagcatta taaggctgtt gtttaatttt
    16441 gctgtaaatt aaatacttaa tcaagattct aaaagtgcta gcaacctcat ttgttaatat
    16501 cttgccacgc atcatatagt ttgcattcat aaacttcaaa aatgtctttg cacttacttc
    16561 aacaacacaa catacactat catcatgacc atcaatctga tacaaatcat tcaacataat
    16621 aacggtgaca tcatttcttt ttacatcata ttgttgtaga ttgattgaaa ctacacctgt
    16681 accttgtagc caatatataa tttttaagtt tgcttccttc acactactca ttttcatact
    16741 tttaaaaata tgtagtgaat aattatctgt catcttacat cctcacatat acaaatatat
    16801 tgatttactc ctgtttgtct ttctcaaatc aattgtcaac atctaatatt cactaccaat
    16861 tatatcgcca catgtttttt agcagtaaca aaacataaat cgattatatc aaataatact
    16921 tttattaaaa cattttttta tgctaaatta ggatatttta tccattaaat atacattttt
    16981 atccaaatac caaagctttc ataatcaaag aaacttgatc gttcgtgtcg aatttttatg
    17041 cattttctga ttaaaagtcc tatattatgc acaaaatata catttagaat tttcagtaat
    17101 attacaaatt tgtaacagac ttattttcga aacattcagt tttcacaaag aatgccgtag
    17161 ttataagttt tgcaaaatgc aaatttctat acttttaaaa ttctattgtg tcaagatatt
    17221 agcaaaaaat tacaaaacgt taacaaagca cacaaggacg ctaatttctg ttatagtctt
    17281 tcttgtcgtt taattacgag agataactta taacattaat tttgtcacac ggacattacg
    17341 aaaatatttt agatttaaaa tttttaggag gatattttta aaatgaagaa aatcgctaca
    17401 gctactatcg caactgcagg attcgctaca atcgcaattg catcaggaaa tcaagctcat
    17461 gcttctgagc aagataacta cggttataat ccaaatgacc caacatcata tagctatact
    17521 tacactattg atgcacaagg taactaccat tacacatgga aaggtaactg gcatccaagt
    17581 caattaaacc aagataatgg ctactacagc tattactact acaatggtta caataactat
    17641 aactataaca attacaacaa cggttatagc tacaataact acagccgtta caacaactac
    17701 tcaaataata atcaatcata taactacaat aactataata gttacaacac aaacagctac
    17761 cgtactggtg gtttaggtgc aagctacagc acttcaagca acaatgttca agtaactaca
    17821 actatggctc catcatcaaa tggccgttca atctcaagtg gttatacttc aggacgtaac
    17881 ttatacactt ctggtcaatg tacatactac gtatttgatc gtgtaggtgg taaaatcggt
    17941 tcaacttggg gcaatgcaag taactgggct aacgcagctg caagagctgg ttacacagtg
    18001 aacaatacac caaaagctgg tgcaattatg caaacaactc aaggtgcata cggtcacgtt
    18061 gcatacgttg aaagtgttaa cagcaatggt tcagtaagag tttcagaaat gaactatggt
    18121 tatggcccag gtgttgtaac ttcacgtaca atctcagcta gccaagctgc tggttataac
    18181 ttcattcact aattagtgat gactaagttt tacgccaaca aggtttcaag agccttgttg
    18241 gcttttttaa tttctatgaa aaaaatcgaa ttggtaaaaa tctcaaaatt tcgattttca
    18301 ccaatccgat tcactctgta ataaagaata aacaacatac agccattgac acacccaaat
    18361 ttaggcacgt caaatcggct atacattgat aaatttttag ttaaagtact tacaaatata
    18421 cttgccttca aattctcaat taatttagtc attacaaatc atgacataaa acttacatta
    18481 catatatcaa catgttccgc tacaaaacat attcagtata tgtatagagg atatttattc
    18541 taagttaaaa ccttttcaaa ttataaccgc tacaattata aatgattaaa gtgtttcaac
    18601 atattatata tattccacgc tcacattaag ttaaacgtga attcgatgac tttttaatac
    18661 ctatccctgt aaaaccatag ataattgcta taattgcgca taaataacat ggtactgtcc
    18721 atatgaaaaa ttctccaaca gagacatgaa gttgattcgt atagtaaata cctgatgttc
    18781 cccatggtat taaaggtaag accatcgtac ttgagtcttc aagtgttctt gataaaacgg
    18841 aacgagagac ttggtatttt tcgaacaaat ctttcattaa cacaccgacc ataataatta
    18901 caatcgaagc aacacctgca gcgaatacaa gcgcaataca acaaataaca gtaacacata
    18961 ttaaacttcc tacagaatgg atgcctttag aaatagtagt taataagact tctaaacatc
    19021 ctgctttttc tacaatacct gcaaatgcat atccgcaaaa tatcgttact aatatttgag
    19081 tcatactcat cataccaccc tgctctaaca agcttttcac actggatgaa atatgagact
    19141 gatgtatcat tgagtcgtta aagccactaa atgttgcttt gaaaccatct gtcattttga
    19201 aatgatgatt aaaagtaccc actataatgg cagaaaagct tgatattagc atagctggca
    19261 ctgtagccat tttaaatagc aaacaaacaa tgatcacaat taagggaacc cagacccata
    19321 tgttaatttg ataaatctgt gcaagctctg ataacaaagt ttgaatctgt ttatcatttg
    19381 aatgcccttt aaattgaaat ccagcaataa accatactaa taaacctatg attgacgcag
    19441 gtatcgtcgt ccacatcatc gaatgtatat gtttaaatat attaacttta gtaacaagtg
    19501 ccgctaaatt agttgtatct gataatggtg acattttatc tccaaataca gcgcctgcta
    19561 taatagcacc cgcagccatt cctggaggaa tccccaattg attaccaata gaaataagtg
    19621 caatccctgc agttgatgca gagccccatg ctgtaccagt tgctacagat gtaacagcac
    19681 ttataaaaaa ggctgatatt aaaaaatagc ttggatttaa taaatctaag ccataataaa
    19741 tcaacgctgg cactgtgcca gaaaacatcc aactgcctac tataattcct accgctagta
    19801 taattaaaat tgcaggcatt gcagtattta aacgttctgc aatgcctttt tctaaatctt
    19861 gccatgttaa gccgacacgt tttgcaatcc atgtggcata tgctgaggca ataattaata
    19921 atacttgaat tggaatatca aaaaacacaa agcctgttac aacaacaata accattacaa
    19981 tcattgtcga aattgattct aaaaaggttg gttttcttgt catcatctat cgtccccttc
    20041 gcttattgat gagaaacctc ttttcttcaa tttattgctt ttacataatg ctatatcctt
    20101 ttctatcttc aagccatcat ttattttaaa tatttttcta aatcaagctt atctaagcca
    20161 atggattcaa ctgttaagcc ttcctcaaag aagtctcttt ctaagattgt cgatgcaatg
    20221 acaattactg catctatatt tggtgtcggt acatcaataa cacgacctaa gcttgaccat
    20281 aatactaaac catatgcaat atcttcagtt aaatatctgc tttctacatg atttggtcct
    20341 ggaatttgtg aaaatactgg gcttgtatta aacaaacgat ttaatggttc atcttcttta
    20401 tcacgttcta aataaccacg ttcaatacgt gattctttag ctgttgataa ttcaaaacct
    20461 aatctacggc ctaaatttaa acgttctaat tcgattgcat gaagtaatct aactgtatgt
    20521 ttagtaattc cttctttata taaagcgaac tcaccagcat aatcaatgcg accgacattc
    20581 aataatgttg gccctggatg cacttcagga ttaccatttt caagatttgt tttaattaag
    20641 ctttcctctt ttactaaatg atcataaata cttgaaactt tgtcataaca atcatttaga
    20701 cagcttctat catatgttga aaagaagata cgacgtacat ttagagataa atcaactgct
    20761 gcattttcaa aatcgacacg cgtaccatac gtcaacgtat tagcttccgc taattgtggt
    20821 tttgtttcaa tatgtctatc ttctaaaaca ttcataaaac gaattgaccc cattgctgca
    20881 gccatgttga agaatatcaa ctgattatca gttacatgct ctgccattac atcagcataa
    20941 tactctatgt atgaagatgg aataatcact tgaacaattt cagcatcttt taaaacatat
    21001 tccatatcat cactaatatc agtgaatttt acgaaacgtt catcaccttc attattaaaa
    21061 tcaaatccgc ccttttcgat tgcgttttga aacttactta tagattgatt acgacaatat
    21121 aatttaacat cgtggccttt gctcaccata tctactgctg ccgtaactgc gccatttcct
    21181 gatcctacaa ttgctatttt cataaacaac cctctttcta tctttggtta aaattaaaaa
    21241 caaattatac gtaagacaat ataaaaatga tgcgaattca ttacgcatca ttataaatgt
    21301 taagtatata taaccttaaa ttaacctatt taaacgccga cgtccaccaa ttatttttat
    21361 ttttaataat tgtttaataa acatgtttat ttttgattat attttgttat agttaaagat
    21421 aatattacaa ttttcaaagg agtgtctaat atgacaactg aaatgaacga cgtaacaaat
    21481 catcaaccga atcgcaaatc caatgatgag aacattatgg cgatgcttat ctatttatta
    21541 agtttattca catctattat tggtccactg attatatggt tattgaaaaa agatgaatca
    21601 aaactagttg atcgtgctgg aaaaaattat cttaactata cgatttctta tattatttga
    21661 tctatcgttt tagtcgttat cacttttatt ggcgttttcc taattgctac cgatattgat
    21721 ttcattatca ttataggttt catcattacg tttatcggta ttttatccat attcgctttc
    21781 tcaatattat cttttgtatt cacaattatt gcgtgtgtca aatattataa tggccaagaa
    21841 tatgtaatac ctttaacaat tcgatttatt taaacatatt acaaataaat atttcctatt
    21901 aattatctgt taatctcatt gtaactttga ctaattttta ttacaaaatt agtcaaagtt
    21961 tttttattct tttacaaatc aataacattc cccacaagaa gcattaattt tgttaaagta
    22021 actattgtca tcaattcgag atgtgagaat aaaacagtcg ctacgtttta tttataaaaa
    22081 aagatataga actttggagg actttattca tgaaaaaatt agtaacagca actacgttaa
    22141 cagcaggaat tggtacagca ttagtaggtc atgcacaaca tgcagacgct gctgaaaatt
    22201 atacaaatta taacaactat aactataata cgactcaaac tacaacgact acaacaacta
    22261 cgacaactac atcatcaatt tcacattctg gtaacttata cactgcagga caatgtactt
    22321 ggtatgtata tgataaagta ggcggagaaa tcggttctac ttggggaaat gctaataatt
    22381 gggctgctgc tgcacaaggt gctggattca cagtaaacca tacaccttct aaaggcgcta
    22441 tcctacaatc ttctgaagga ccatttggtc acgttgcata tgtagaaagt gtaaacagtg
    22501 atggttcagt tacaatttca gaaatgaatt atagtggcgg acctttctca gtaagttcta
    22561 gaactatttc tgcaagcgaa gcaggtaact acaactacat ccatatttaa tataaacacg
    22621 atgatacata ttgtcttgaa acttaattct agtacatatg tcatcaaaaa actttgagct
    22681 ttcctttata ggagaagctc tttttttgct atttttcgtt gccacctact tatttatatt
    22741 tcccccccat attcataata ttaatttttt caatactatt taactttaaa actacgttat
    22801 ctaatttaat tgatccagtt tttccacatt acaatattca tagttctaca gtgcctaagt
    22861 tatatcacct ccatcaaaag tacacgctta catcattgat acacaagaca tcatgacata
    22921 gttgtatact gtctaatctt ctactatact aagataaaag gagtgatctt ttatggaaaa
    22981 agtttatgtt gctggtgcaa taccagaagt aggtttaaaa cttttacaag aacattttga
    23041 agttgaaatg tatgaaggta aaggattagt cgataaagac actttaatta aaggtgttaa
    23101 agatgcgact gccttaatta gtttattatc tacaaacgtt gataaagatg ttatcgatgc
    23161 tggtaaagac ttaaaaatca ttgccaacta tggtgctggt tttaataata ttgatatcga
    23221 gtatgctcga gaaaaaagta tagatgttac aaacacacct aaagcatcaa caaacgcgac
    23281 tgctgattta acaattggat tagtacttgc agtagcgcgt cgtattgttg aaggcgacca
    23341 attatcacgt acaactggat ttgacggatg ggcaccttta tttttcagag gtagagaagt
    23401 atctgggaaa acaatcggca ttatcggttt aggtgaaatt ggtagtgcag tagcgcgtcg
    23461 tgcaagagca tttgacatgg atgtactata cacaggacct aatcgcaaag aagaaaaaga
    23521 acgagaaatc ggtgcaaaat atgtagattt agatacacta ttaaagaatg cagattttat
    23581 cactatcaac gctgcttata atcctaaaat gcatcattta attgatacag aacaatttaa
    23641 aatgatgaaa tctacggcgt atttaatcaa tgcctctcgt ggtccaatcg tgcacgaaca
    23701 agcactagtg caagcattga aagataatga aattgaaggt gctgcacttg atgtatatga
    23761 atttgaacca gatattaccg atgacttaaa atcacttaat aatgtagtat taacaccgca
    23821 tattggtaat gctacatttg aagcacgtga catgatgtct aaaattgttg ctaatgctgc
    23881 aattagtgcc gttcaaggtg agaaaccaca atttgtcgtt aactaataat tgaatttatt
    23941 ataatgacat tataaaaaca agaaccccca tatgttgagc tctcatttca acatacgggg
    24001 gttttcatat tgttgtatta tttctctttc gatttatata agaatttagt ttgtccagct
    24061 gctaatgcat ttggcatcat tttcataata cgatttctaa ctgcaacaac taaacgacta
    24121 cgatattggg caattttacc gatttttcta gaacgcttaa ttacttttgc agtatgtttg
    24181 acacgtattt tatcataacg ctgtaatgct ttttcaaagt cgtatgcgtt aaaacaattt
    24241 actaatacga tagcatcttc cattgcttgt ccagcacctt gccccatatt aggcgttgtc
    24301 gcatgtgctg catctcctag taaaatagta cgaccataaa caaaagattt gagtggtttc
    24361 aaatcataaa tattatgcaa taagatacct gtttcacttt gtttgtctaa gatctctcta
    24421 acttcatttg gatagtgatt aaagtatgct tgcaaatgag gtttaccaaa cgaactatat
    24481 ttatgattgt tttccttcga gttgattgta atgaaccaat atgcttgatt atttaataac
    24541 ggaacaatac ctactcttcc ttttcttccc cagtattctt ttgcacaatc cggatgcttt
    24601 aaatcaatat catcaattaa acctctaaag catgtatacc cttgatataa tactttactg
    24661 tcagcattta cagattgtct cactttagaa tgaattccat cagcaccaat acataaatca
    24721 aatgcttcac tctcttgttc cgcgaaatgt atggtaactt tatctgtctc attatctata
    24781 tgcgtgactt catgatttgt aaatattgta tcatctttta cataagattt aataatgtca
    24841 attaatgttt ggcgtggtaa cgtcacattc aatgtattac tttttaattt aacagtagtt
    24901 aacaggcgat ctttgtcatc taacactgtc attgtagata agatttgccc agcattttta
    24961 atacctttag ctaagtcatg attacctagt tttttaagca cattatctcc gataccaatc
    25021 ccagcgccaa tttctttaac tgactcattt ttttcaaaga ctttaatagt atgaccttgt
    25081 tcttgtaata atgcagcagc tgttaatcca ccgatgcctg cacctataat tgctatcttc
    25141 atattgtcac ctctatattt ttcattcttt tctattttat cacatgcact attgtttaaa
    25201 aatgactctt ggaactaacg tttcattttt aaagacttaa gtgtattatc tgcaccattg
    25261 tatattacat gcacatttag acagcaatat tcatttacat aatgtacatt tgtaacaatg
    25321 atgtgggata tagcatattt gatgctatat agcgtttttt gttaggttaa aatccattta
    25381 actaacacac tcagaatgcg ctaaaggagc tcgaaacaat aaattgttcc agctccttta
    25441 agcactgatg tcttatttat aatatatttg tctaatatca tctttcttta taccaaactg
    25501 cttatagcat ttatccatta attgggcaat tttatctgcc cagcgaatgt cactcgcata
    25561 ttgatgttgc gcaggatttt ctggattcca tcgcatttga tataaattca gttgattgtt
    25621 ttcaaaatat tcattacgaa tgaactttgc accaccaata atcgccttat ctggtgatgt
    25681 ccattgttcc ttttcagcat aactttttcc actacgaaca gcactactat cgaatgctcc
    25741 tataccaaaa aagttgtaat agcgtttttt tccatcttta atgccttttg ctaattctga
    25801 tttgccgtta cctgtttcta ctaatgcatg gctaacaaga taaatgacat taacctcata
    25861 tttttcttga gcttctagaa aaactttccc tcgattttct aaaatcccct taccttttag
    25921 caattggtta acttcagatt ccgacattgg cactttttct gtgatatcca tatacttcat
    25981 atcattgtct ttatgtgaaa tagtcattgc tttagcaatt tcattattat ttgcttcaac
    26041 aaatttacca tcctcttctt ttgtctgtac aatacctttc ccttgttgca ttgaaacagc
    26101 ctcatcaaaa gagtaattca catcattttt aaacaattta gtttcattca cgatgagtaa
    26161 tacagcaaaa acaactaaaa taactatcaa tagtagcgtt gaaatgcgta acttgaaatt
    26221 cttcttcata tagacaaaac ctcatttttc ttacttagac aataaaaaat atgccactac
    26281 aatcgctaat attacgatta aaaaagaagc gttaacgatt actttcatcg ttgttctatc
    26341 tctgaacatc atattaaaga caactagact aattgataat gaaacagcaa aaaaagtaat
    26401 agctaacact aatttcatca taaatagaca gactaaacct atgactaata atgtattaga
    26461 aattacagct gacgttttta acattctcga attaatatgc actcaccctt tttatttaaa
    26521 taacttacat aatcataata atacatgatg tttcataggc ctgtcgatga ttgattcata
    26581 atagcacgtg atttttttgt ttttcaatgt tattcattta ttccatcaaa aacacccttt
    26641 ttaattttta aaaaaattaa aaaagtgctc ctacactgct tgcatgtaga aacacttttt
    26701 cattgtaatg ttaatcttct cgagacatac cttttagcat attaagcata tatgttaaac
    26761 tacggttcat gtcgtcatct tttaaaacgc ctaacagact tcttacagat gtcttcgcat
    26821 taggactcgc ttgatttgca acatgtaatc ctttattaac tttattaagg aagtcactta
    26881 aatctgatac atttaattca cctaataaaa ataccattga tgccatattt gttaatagac
    26941 cagtatagat atctttgttg agctcaacag caaatttatt aataatcact tgacgtcctc
    27001 taactgcgcc atttaaagca tctaatattt tagcatcatc taacacttta ataagtttga
    27061 ttgcttttaa tatactatct ttattcgctg caattgcctc tgtaacttca tttaaacttt
    27121 ctaacttaat ttgttcttct gatttttcta agcgtctaat tttagaagat attctctcag
    27181 ccattattta tccacctgat ttcctgggaa aacataatct ggacgttccc attttttctg
    27241 tacttgaaca ctgtactgcg gatgacgttt tttattgaca cggaaattat ttgggttcaa
    27301 cggtgactta ccacgtttcg taattacctc caaacgacag cttgtacgtt tataagatgg
    27361 tgtatccgtg tattgatcaa catcactatt agttaataag ttaattgcac ctaggtctcc
    27421 attttccatc gcatcattat ttaatggaat atagatttct ttacctttaa cacgatctgt
    27481 cacgtgaact tgtaataccg cttctcctgt ttcagaaatc aacttaactt ctgcaccttc
    27541 atgaatgcct ctatcttcag caagctctgg agaaatttca acaaatgcac gtggcacttt
    27601 gtatttaagc attggtgttt gatatgtcat gttaccttcg tggaagtgct ctaacaatcg
    27661 accattgttt acatgaatat cataaacttc atcttgctta aagtaattat caaatgataa
    27721 tgggaataat tttgctttac cattatcgaa attaaatcct tctaaataaa gtattggttc
    27781 atctgtacca tctggatgca caggccattg taaactattg aatccttcta aacgatcata
    27841 acttacccca gcatatagag gtgttagtct agcaatttca tccataattt cgcttggatg
    27901 tttgtaattc caatcgaaac ctaatttatt agcaattgct tggaatattt tccagtcagg
    27961 tttagaatca cctaatggtt tcaatgcttg gtataaacgt tgaatacgtc gctcagtatt
    28021 cgtaaaagta ccatcttttt ctaatgaagg acttgctggt aagacaacat ctgcaaatgt
    28081 agctgtaaat gttaaaaatt catcttggac taccatgaaa tctaattttt caaaagcagc
    28141 ttgtacaaaa ttaatatttg aatctacaat accagtatct tctccatata gatataatga
    28201 atgaatgtcc ccatcatgga caccttcaac catttcatga ttatctttac caactttagg
    28261 attcaattta acgccatatt ctttttcgaa tttagcgcga atatcgtccg cttcaatact
    28321 ttgatagcca gtaattttat caggcatact acccatatca ctacaacctt gaacattatt
    28381 atgtccacgt aatggatacg cgcctgtacc aggtcgacga taatttccag taactaataa
    28441 taagtttgaa attgctgtac ttgaatcact tccaatgtct tgttgtgtga tacccattgc
    28501 ccaacaaatg acaacggact cagctttggc acattcttca gcgaacttaa tcaactctgc
    28561 ttctggaata ccagtagcct cttcagcgaa tgccattgta aatgtttcta atgacttgta
    28621 atattcatca aaatcttcaa cccactcttc gataaaggct ttatcgtgta agtcatgatc
    28681 aatgatatat ttcgtcactg cacttaacca cgctaaatcc gtacctggtt tcggttgata
    28741 gaaacgatcc gcacgttcag ccatttcatg ttttctaata tcaaacacat gtattttttg
    28801 tccaaataat ttttgagcac gtttcatgcg tgatgcaata accgggtgtg cttcggctgt
    28861 attcgtacca atcaatacag acattgctgc tttttctaaa tcttcaatac tacctgagtc
    28921 accgccgtgt ccaaccgttc taaataagcc ttttgttgca ggtgcttggc aatatcttga
    28981 acagttatca acgttattag tgccaataac ttgtcttgct aatttttgca ttaaatacga
    29041 ttcttcattc gtcgctttag aagaagaaat gaatgatagt gcgtctgggc catacttttc
    29101 tttaatagat gtaaaattat ctgcaatgac atttaatgct tcatcccatt ctacttcatg
    29161 gaactcacca tttttcctta ctaatggttt cgttaagcgt tgatctgaat taatatgtcc
    29221 ccatgaaaac ttacctttaa cacaagtcgc aattttattt gctggagaat catgtgatgg
    29281 ttgtactttt aaaatttctc tatctttagt ccaaacttca aatgaacagc ccacaccaca
    29341 atatgtacac actgttttag ttttcttaat acgctcttta cgcatttctg cttctgaatc
    29401 tgagattgca aatagtggac cataaccagg ttctgctttt ttagttaaat caatcattgc
    29461 cgctaatgaa ccaggttccg tatcagtcat ataacccgca ttaccttcca tattcacttc
    29521 catcatggca ttacatggac atacagttgc gcattgacca caagatacac atgaagattc
    29581 attaatcggt acatcattat cccaaataac acgtggatgt tcacgatccc aatcaattct
    29641 aatagtttca tttacttcaa tatcttgaca tgcttctaca caacgcccac ataagataca
    29701 ttgatttgga tcataacgat aaaatgggcc gtaatctttt tcgtatggct tctctttata
    29761 ttcatacgtt tgatgctgaa gcccccatgc atccatcgta ttatgaattt cacaatcacc
    29821 attattataa tcacatactg tacaatacag catatgcttt tctaaaattc gatcaagcgc
    29881 ttctttttga gcatctttca catcattatt cactgtattt actgtcattg gacgatcaat
    29941 cactgtacta catgaacgtt caattttacc atcaatctca acagtacatg tatcacacgt
    30001 ttgaattggt cccattgatt cgttataaca aattgaaggc acaaaagtat cttgcgattt
    30061 aatgaattca agtaaatttg tacctggttc tacaagataa tctttaccat caagcgtgac
    30121 caccaaatgt tcttgcatac tattcacccc atctatatat ttttccgtaa atgactttta
    30181 ataaattgct catatccacc taaaataacg atgccccaca catctttcag atagaatcaa
    30241 tataattgta ttactttaag tgtataatgt taagcgtatt tttgtatttt ttatttttgc
    30301 aatcattttt atttgaaata ttttgcgcga aattaaatca tctttttgtt taattgaaaa
    30361 taattatcat tattagcttt ccaattatct gtttcacgct tttttgccat atctttcaca
    30421 accttattaa tgacaatact taataagtag ctcacctaaa aatcgttata ctatttataa
    30481 ataccctttt tctgaaaatt aataacccaa gtctgataaa tatctactgt catttagaag
    30541 gtatgattta tttttaaatt gaatttgtaa tgggttaatt tacaaaaccg catatcaggc
    30601 attaaataaa ataacccata aataaaaagt gttatcacct tctatttacg ggctattaat
    30661 tctattcgtt attcttttta cagctcattc tatctaatta gtttgtgtac aattttgata
    30721 acttactttc ccttagttta ctactctaga ttatctttta ataacttagt actttcagct
    30781 tttgactgct cactaggaat gaagtagtac aatccgtcac tttgaatgcc gccttgacca
    30841 ctcaattgat gtttattaat cgtgtcatta gcatctttat aattgcttct aatcgtattc
    30901 aaatcaccta atgttaaatc tgttttaaca ttattttgaa tttcattcat tagactatta
    30961 aaatgtgtaa tcgatgatgg gcttgcaatc ttattggcca tcgcttcaag cacaatttgc
    31021 tgacgttgtt gtcgaccaaa gtcaccacca gcaccttctt ctttacgact tctaataaac
    31081 ttcaatgctt gatcaccatt tacatgtgtc tgctgtcctt ttgtaaaacg aacaccatca
    31141 acagtgaatg tatcattact tactacatca acaccgccga tgctatctat catattatgc
    31201 aaaccatcca tatcgattgt cgcataatga tcaattggca cattcattaa tttttcaagt
    31261 gatttaacag ccatatttgg tccaccatat gcataggcat gtgcaatttt ttcagtagta
    31321 ccacggccaa caatttctgc tcttgtatct cgcggtatac ttactatttc agttttcttc
    31381 gttttagggt tgatagataa aatcataata ctatcactac gctctccgcc accctttttc
    31441 ttacgatcag catctgaatc gacaccaaat aaagcgattg tgaatggatc accatcgttt
    31501 aaactcactt ttttatctct taattctgaa tgattgcgat ctaacggatt gtgtatctta
    31561 ttaccagtaa taaaaatttt agcagctaca tacacaacag ctacaatcgc taagattact
    31621 aaaataccga atacccataa aaatattttt ttcggtaggc tcattttact tttagacgaa
    31681 cgtttcaatc ccaccactcc tttactattc cttacatact ttgtctgttt tctctattta
    31741 ttatatagta aaataatttt tttactatac ttctgtagac gtataactat tttttatcat
    31801 tttttatcac tatagaatat ctatctgtat ttttgataac caccatttgc atttaaaatt
    31861 ttaagtaccg tttcatgaca tgcttgatta cttataataa aaggtgcacc ctttaaatga
    31921 tcaattgcct taccatctaa agttgtcatt tttagattca atagttctgc aaataaaaac
    31981 tgcgcagcaa tgtcccaagg tttaggattt gtattaatat gtgccccaaa ttgacctttt
    32041 gccactcgca tagaatctaa tccgcaagca ccaactaaac gataactaaa tgaggcgtca
    32101 aataaatctt gcaccgtatc cagattcatc acttgtgcat taaacgatat aatagcgtct
    32161 tccaatttta acgatggtgg ttcttccatc ttaattccat tacaaaaagc accttctcct
    32221 cgtagtgctt tataaagctt tttatgcgga taatcatata catacgataa cattggttta
    32281 ccttcataaa aatacgccaa tataatacaa tactcttctt gctgttttac taaattggca
    32341 gttccatcaa tgggatccat aatccataaa tgattaattt cattcgtaat cattttatta
    32401 cttttttctt ccgctaatag ttggtgttcc ggaaaatgcg ttgctaaaaa ttgttgaaat
    32461 tgttgttgaa tctgtttatc tacatttgta actaaatcaa atcgatgacg cttggtttct
    32521 gtagtcatct ccataattaa ttgtggaata acattgtcta tttgtttcaa ccacgaacat
    32581 attaacttat ctatttgctg taatgtttta tctgtcactt cgtccaccac ttctcatatc
    32641 attatcattt tactattacc ctatattaaa agaatcaaca atacaactga agacttcttc
    32701 tttttgtgca taaaaaaatc ggctagtcac gtgctagccg acaaatagaa aggaaagtaa
    32761 gtaataaata ttgaagatgt tgtgatgtaa cttgaacgat taaaagctat ctgttatata
    32821 gctctacccc tttgtttaat cgctccccct gttacaagta atatcatagc acaatctttt
    32881 ttaaaatgta agcgttttct acaaaatttt tccgattttt ttaaaaagat attgaaaatg
    32941 tcctcattgt cactcttatg ttatactttg tgtaatatat catcttttag gaggtggctg
    33001 tcatgaataa agctgaaagg caaaatttaa taattactgc aattcaacaa aataaaaaaa
    33061 tgaccgcttt agaattagct aaatattgca acgtatccaa acgcacaatt ttaagagata
    33121 ttgatgattt agaaaatcaa ggtgttaaaa tttatgcgca ttatgggaaa aatggtggtt
    33181 accaaataca acaagcacaa tctaaaattg cattaaactt atctgaaaca caattatcgg
    33241 ccttattttt agtgcttaat gaaagtcagt cgtactcgac attaccatat aaaagcgaaa
    33301 tcaacgcaat tataaaacaa tgtttaagtc ttccacaaac acgcttaaga aagttgctta
    33361 agcgcatgga cttttatatt aaatttgatg acacacaaca tatgacactc ccaatgttgt
    33421 tttccgacat tttaatttat tgtacagaac gaaatgtgat gttagtagat catagggttg
    33481 atgataatat taaagccgaa aacgttatat ttattggcct tttgtgtaaa catggacatt
    33541 ggcatgcagt catttatgat attgctcaag acaaaactgc cgaactcgaa attgaaaata
    33601 ttatagatat ttcgtattca ttcggtaaga cgattcaaac cagagacata tccattgata
    33661 actatcatca atttttaaac cccatcgatt cctaaactat ggagtcgatg gggttttatc
    33721 tacgcataaa tacttattac tgatataacg aaagaaacaa aattatttgc tatatgtaat
    33781 gcaattgttg aacctaggtt tcttccagat tttatataag tgaaaactaa tatgatggat
    33841 agtatgagat atggaccaaa ctcaaatggc gactttgcat cagtcacatg aataaatgca
    33901 aataagaaca ccgaaacaat actcatagct ataaaattaa acttcttacc taattctcca
    33961 attaaaatat gtctaaatac gatttcttca actattggac ctacaatcac aattaataag
    34021 aatgctacag gtaaaaatgc aggcacttca aacattttat ttagctcaag ttcattggct
    34081 gtttcactat attgcaaatg tttaggtaga aactgtgtca tatattcata tgtataaatt
    34141 aagatgagag caataatata cgttattgac aatctaagcc aatatttttt gatatacgca
    34201 aaaccagctc gaagccttga tggcatcact tttaaatgaa ataaataaaa tgcgccaatc
    34261 ccaatcgtat atgctaaagc ttgtgtgata gtcgctacaa atatcagatt actatcgatt
    34321 ttataataac caaacaaaat tggtcctatg taagctgcaa ttgtgagtgc ataaaatata
    34381 acacctataa ttggaattat aagcaaatct ctccatgcta tatctttaaa cgtgtatttc
    34441 tttttttcat tttccactgt tatatccttt cctgtttaat aattgatttt tggaggtact
    34501 tctacatgat aaacgaaact aagtatatga gacaacaaat tactaatttg attcaaatca
    34561 ttgatacgat taaatataat actttaatga caaattggaa cattcaaacg catatttata
    34621 aatttaacca aatagttact aatgaattga ataagttcaa aggctttgaa acatcatata
    34681 taataaacga aaagcaagtt ttctattatg aaattataac actacttaat aaacgtcccc
    34741 tccgacaagt cgactatggt aacaaaattc aatatcttaa tttttatcat acagaactat
    34801 ctaacgcatt atttgcaatt aaatttgctc attaacctat ttttcataaa atgtcattta
    34861 aacaagttat ttattaaaat tcactttatt acataaatta tacaattaaa aagtttcttc
    34921 aaattgtaaa gatgcattaa tcgagttata atcataatga ttaagatggt agatttagtc
    34981 ttatataact acatttacta agatttaaat agatgagtac ataatgtata aattgggaat
    35041 atacagtatg acttacggta atatatcaat atattgatat attatttgca catgggagta
    35101 tgctattttt tatctataca tcttaaaaaa atttacagtt ttataattca atatcattaa
    35161 acaaacaaca tattcagctt atttttcatt ctctaacgtt acaagttgta aataccatcg
    35221 cgttaaacaa caatagccaa cgctaataaa atatattgcg ttaaagtgga gtgattaata
    35281 tgtcaaacgt actaacagaa atagatagtc aatatccata tatgactaaa aatgaaaaaa
    35341 agatagctaa atttatacta aattcacctc aaaaggtgat taaaatgagg tctcaagact
    35401 tagcaagctt attagatatt agtacatcat cagtcattcg atttagcaag aaaattactg
    35461 atggcggttt tcacgacttg aaaataaata tatctaaata tgttcctaaa gcatcatcaa
    35521 tttacaatgt tgaattaatg aataacgaaa gcacagaatc tttaagaact aaactccata
    35581 cacgtactac acgcgcactt aatcatgcaa ataacgaatt aaatgataaa actattgatc
    35641 aaatatgtca ttgtttaaaa cgttctgaga cgatttttat atatggtttt ggcgcatctt
    35701 ttgtagttgc taccgactta taccaaaagt tatcaagaat aggtcttaat attcaacttg
    35761 ttcaagaaac acatattttt gcaacattat tagcaactca caattcgaat gacagtgtta
    35821 ttcttattac taacaatggt acgcaaagtg aaatgcaatc aatggttaaa gttattgatg
    35881 actaccatat acctataatt acaattacta gtacaaggga taatcccgta gcacaggcat
    35941 caaatattgt tttaacttat gggaaaactg atgaaaatga gatgcatatg ggagcaacaa
    36001 cttcattatt tgctcaaatg ttcactattg atattttata ttatcgttat gttgcattaa
    36061 attatcacgc atcattagat ttcataacac aatctaaaat ggctttagat aactatcgta
    36121 aacatttatc aaatattaac tttaaacatt aacagtctta tataaattct ttaatcatgt
    36181 catataataa tttatgcatc attttcaaag cttacatgtc ttttatcttg tataacatac
    36241 gcatatgacc aatgatttga taaggccatt caatttctta tattaaaaac aaacgcagtt
    36301 gattaacgga ttcattccat atatcaattg cgtttgttat tttaataaag ctatttttta
    36361 ttttaaagcc tacagtaaaa actaacgata gtattgccac ttataagtaa attcatacta
    36421 catctttgat ttaagctata tttataaaaa aatgcgccta ctcataacat ttctttggct
    36481 atttaacttt aataagctag ggccaagttt gtcataaaat aagcgcacat tataatcata
    36541 ctattttgct tttacattat ttttattata tctaataaaa taataaatcg ttacaatcgt
    36601 taagaagata acaccaataa gcactgatat tctagtttca acattaaata ccataccaac
    36661 caatactaat attaaaaata agattgttaa atagttagtt actgcgccac caggcatttt
    36721 gaatgggtga ccttccactt cttcagggtg taattttcta aaacgtaagt gactgaataa
    36781 aatcataaac caaggaatca tacctggtaa aatagacgca ctataaacgt atacgaaaat
    36841 actcttcgct ccatcgatat ataaaggtaa aattacgttt aataaagcac caattaaaat
    36901 accaagagat actgcaacaa cagtgtacaa tggcacacca tttctcatga ttttagtaaa
    36961 tattttcggc atttcacctt tatgagcaag tgtataaatc atacgactcg cactgaaaat
    37021 acctgagtta catcctgaca ttgctgcagt taatacaaca aagttaatta atccagctgc
    37081 aaatgtaata ccgatttttg caaatgttgc aacaaacgga cttccaatgt ctcctaattg
    37141 attccaagga tacactgaaa caataacaaa aatagcacct aaatagaaaa ttaaaattct
    37201 ccagataaca ccattcactg ctttaacgat atttttctga ggatctttag tttcacctgc
    37261 agtaatacct atcagttcca caccttggta tgaaccaatt acaattgata atgcaaagaa
    37321 gaaaccaaca ataccatttg gcataaatcc gccatttgtc catagattag aaatacctac
    37381 cgcatggcca ccatttccaa aaccaaagaa aataagacca aaaccagcaa taatcattaa
    37441 aataattgtt acaactttaa ttaaagcaaa ccaaaattcg aattctccaa acgcttttac
    37501 cgagaataaa ttcgctgcca tcaataataa aatagcaata ataccaggaa tccaggttgg
    37561 caattccggg aaccaaaact tcatatattc tcctactgcg atgacctcac tcataccaac
    37621 aacaatccat tggaatatat tactccatgc tgtcatataa cctgctgcag gatgtatata
    37681 atcacttgca aatgttgcaa atgatcctgt tgtagggttt aaataaatca tttcccccat
    37741 tgctctcatg attaaaaata aaaagatacc cgcaattaaa tatgcaagga taactgatgg
    37801 gcctgtccat ttaattgtac ttgtagcacc catgaaaagc cccacgccaa tcgtaccacc
    37861 aagtgcaatc atttgaattt gacgggcact caatcccctt tgtagttcat tgttctccat
    37921 aacttcttac cccatctctg attgatacta aataaatcca taaaaaaact tattgccgta
    37981 attatactat aaattaccga ttttggtaca ttaatatttg cataccatgc aatcgtttac
    38041 agaactacta tagcaggctt ttgcaacttt gcaaacaatt attttgtgat ttttctaaaa
    38101 aaataaaaaa gttgttcgaa aactattaag tcacatacaa cttcagctat tctcggtaat
    38161 tatgatataa ttttaataat attacaaagg agtatatcaa tgttaaaaca aatactgcca
    38221 cgtgctacaa aaatatcgat actctttgct gtagcatttt tcatcataaa ttatatcggt
    38281 atggaaaaac ctgacatcct atatttagtt ggaagaacta ttattgcaac acttgttttc
    38341 atactcattt gtcttacatt atttactatt attaattctc cagagcgcaa gattaaactc
    38401 ggtacgactt taccgattgc attaattatt ggtatcattt tcggcgccat atttttaacg
    38461 gtacaaatcg gtgtcatcac tgggttaatc atcggtgtga ttgctacgtt tatttgggaa
    38521 ttgattgaaa aaaataaagg aggtcgttca tcatgacaac agcattaatt ggtgtaattg
    38581 tattaatctt actaattatt agctttgtgc caaactaccg tgctatgaaa tcagcaaaag
    38641 aacaaggaag taatgcaaca agagctacaa ttatggtagg catagatatt atcttaattg
    38701 tacttatcat cgtgacgtta ttattaaaat atatgtaact atttaaacca ccctatctca
    38761 tacataaaca tgaacgttct accatttcac atacatatgg tcgtccattt aatgaggtaa
    38821 ggtggttttc tcgttaaagt ttaccttgta atagtaaaaa atagccaatt gttgcgagta
    38881 ttaagtaaat cattgaacca acaacaaaag atcttacttg cacgtgaaat ggtgtctgtt
    38941 tgttaaatat aggaccaatc accaaatttc caacgcctaa aattactgga ccagctagaa
    39001 aaaacaatat aatgtaaccc atcatgatac gcctcctatt tcgtaaagaa acgcgctaca
    39061 atttgatcgt aatcaatatc ttttgctaca taatctacat tagaaaagtc ctgtgcgctt
    39121 gtcattttat tcgtattaac aataacatct aatccagctg caatcgcggc tgttgcacca
    39181 tttacagaat cttcaatagc caaacattgt gtcggcatat aatttaattg ttgtactgca
    39241 gataaatata attcagggtc aggtttaact tgttcaacat cttctctacc aacaactacc
    39301 tctatataat cgtctagacc taatgcttta aaggtaggca ttatttccgc tttcacacta
    39361 cttgtggcaa tcgccatagg aatgtgacgt tgctttaaaa atgccatcaa tgatttaatc
    39421 gtatcaatca tcggtaatgt tgtactagta agatgatgtt cttcataaag tttatcttta
    39481 ttttccgaac caatcgcttt aattaaatgg tcatgcaaat ctgtagctgc tcctccaata
    39541 gaagaacgat aaaaatcaat gcttatagga tcggcattat gcatctctaa atgtttatta
    39601 ataacattaa ataaatgttg ttccgtatct attattgttc catcgaaatc aaatataact
    39661 gctctataca tatatttact cctctatttt ttctctttat caaagcttaa catagtccga
    39721 tgaccacttc attctattag tgcaattata acttttttga ccaatacttt gctaaaatag
    39781 gccctgttat attatgaatg aaactaaaca ctgcgcctgg tactgctgca attggattaa
    39841 aatgcaatgc tgctaatgac acagctaaac cagagttctg cattccaact tcaatactga
    39901 ctgctttttg atcttgtcga tctaatttta aaagacgagc taaccaatat ccaatcgtat
    39961 accctaatac gttatgtaaa ataactacta aaaatattaa taatcctgta gttaagattt
    40021 ggtgcttact gccacctaca actattgcta aaattaatga aatagcaaca actgatataa
    40081 tcggcaaagc tgtagaagct ttttcagcaa ttttacgatt aataatttgc aaaacaatac
    40141 ctaaagcaat tggaattaat acaacttgaa caactgacca caacatactc aggaaagata
    40201 cttccaacca ttcatttgca aatagatata ttaacgcagg tgtaacgaat ggcgctagca
    40261 acgtagagac cgtcgtaata gaaacagaaa gtgctacgtt agctttggct aaataactca
    40321 ttacattact tgatgtccca cccggacaac atccaactaa tattacgcca acagcaatat
    40381 caggtggtaa atgaaaagac tttgcaatta taaatgctaa tgtgggcata atactgaatt
    40441 gtagacagac accaataatt actgctctag gtgctttaaa gaccattttg aaatcattag
    40501 gtgtaattgt taatcccata cctaacataa caataccaag taaataaggt acccatttac
    40561 ctaatgtcgc aacatgttgt gggaaaataa atccaataac agctgctact aacatccata
    40621 ccaaaaaact cttcgtggca aatatactca atttttgaaa cattgttaac acatcctcgt
    40681 cgataatatt gaaaaatatt accataagac cagtaaggtt acaattactt ttctgaaaat
    40741 taagattatt tagccattct cttcttattg caaatatttt atcactgata aacaattatt
    40801 ttaaacttca ttcaaaagtc ttagtgaata aagaaaaaaa gcgtggtaaa atcaacttga
    40861 acaaaattaa gtcaccttta taaatattaa acgtgtattt aatgccatgt attcctcggg
    40921 aggtcctcac atgttaattg ataaattcga aacatacatc atcaacatcg ccggtttaaa
    40981 tgaccgtact actagaaaaa aattaagtaa gttatgcaaa agtgtacaat tttgtgatgc
    41041 gttgcaattc tcaataaaca aacagtttaa tcagtatgta ttagaaatta gcttaccaaa
    41101 gcaacaactt ccatacttca tttcattttt aagttttcat cagtatagta ttttccaagt
    41161 actttcacca aagaaaataa atgaattact tgattctgat aatttatatc aatctgcaaa
    41221 gcgtttcgat atcaatattg atggcttgca agatgctttc attaaagaca aagtcatcga
    41281 tattatgaat atgttccaaa atcacactga tatcacttat acgttgaata agtctcatgc
    41341 acatattata tgtacgccag aaatatttgc taaattgtta catacgattg caactagaaa
    41401 tatcgacatt ctatctgcca attatagatc gtcatctatg agcaaagctc gtatatcata
    41461 acaaaagaca catctatacg atgatcattt acaatgattg cgtatagtga tgtgtctttt
    41521 tttatattat ttatcttcgg acgattgatc ctcaaccatt tgttcaaatg cttcacgaac
    41581 ttgtggtact gtcataccta ctacaacttg gatactctta ccactcttta ctaatccgtg
    41641 tgccatttgt tgatgcgtga aatattccgt atccgcaact ttactttcat cataaacagt
    41701 taagcgtaat cttgttgtac agttagtaac atctttgata ttttctttgc cgcctaaacc
    41761 gtcgaggtaa tacgcagctt tgtcttcgta ttcattacct gttgaagcac gtttagaatc
    41821 tacgctatca ccttttttat ttttgtaatc ttgcttagaa aataatttaa cttcctcttc
    41881 tgttttctta cgtccaggta atggaatatc aaatttcaaa attaagaatc tgaataagaa
    41941 gaagtaaatc gctacaaata tcagaccgat aataacttgt gcaacataag taccccaatg
    42001 ttctttacct aatggcaacc agtttgttga aataaagtct aacaagccac cacccatgtt
    42061 acctacaaca ccaaatgcgt acattaaagt atccattgat gctgctaaaa ctgcgtgtaa
    42121 aacaaataag tatggtgcga tgaataagaa tgtaaattct aatggctcag taatacctac
    42181 aacgactgct gttaatgttg caggaataag taatgctgct acttttttac gattttcttt
    42241 aggtgtcgta gcatacattg ctaaagcaat acctaaacat ccaaatactt tcccatttcc
    42301 ttgaagcata aagccataag ggaattgctc ttttaatggc ttagtactct tagcaaactc
    42361 atttaaatgt tgtaaccatt cagctttcaa gccgtgattg actactactg gtccaacttc
    42421 aattggtgca taaataaagt gatgtaatcc tgttggtatt aatacacgtt ctaagaagtg
    42481 atacaaccat acaccgatat agcctgaagc aatgataaag tgttgcattg aaccaatacc
    42541 gtgctgaaca gttggccaaa taacacaagt aattgctgct aatggtaaca tcacaaaaaa
    42601 tgaaattgta accacaaatg ttaaaccttg gaatacacca accatttctg gtaatcgttt
    42661 actatagtat ctattgtgaa tccaagtaat aatagctgaa ataataatac cacctagaat
    42721 attcgtatcc aatgtggcaa tacctgcaat tgattttaaa ccaggtacat tttcaacgcc
    42781 tttttctaaa tttgcgccaa acgtatgtgg ccattgcgtt aaaatagcat ttataaatgt
    42841 attaaacatt aagtaaccca tcaatgctgc aagtgctgca tgacctggtg cttttttagc
    42901 taaagaaagt ggtaaaccta caacaaatac aacttccata tgcgtaaaaa taacccagcc
    42961 accagattct atcactgacc aaaatttaaa ccaaaacgta tgttgatctg ctaaactccc
    43021 catgattgta ggatttttaa ataatgtcgc aaagccaagc actatcccaa agaaagcgaa
    43081 cattaatact ggtacaatca ttgcactacc gaaacgcttt atcgcattca tcttctattc
    43141 cctccatatc atctttccta acaatacatc taattagatt catttataaa tagatgtctt
    43201 actatttaaa tataatatat agtaaacgct tacacaccta caacgacatt gacgtatttt
    43261 gaaagtattt tgtataatca gattatcttt tcatatagtg aaaatttttt cacaagcatg
    43321 tcaagaatat gcttgatttt aaaatatgta agtactttag ccatttataa ccttatatac
    43381 aatcaagaat taaattttaa aaatttcacc ttttaatgta aaaaccatat atcacaaatt
    43441 tatttccaag gaggttgaat atgtttttag acgaacacat taatcgaaac tttgataaac
    43501 ttaatgacaa tgatttacat atcgctcact ttatcaatac acatatagat gaatgtaaaa
    43561 atatgaaaat acaagattta gcgcaattca cacatgcctc gaatgcaacc attcacagat
    43621 ttacacgcaa attaggtttt gacggttata gcgattttaa atcgtacctt aaatttgaaa
    43681 gtaataagac acaccaatta ccatctaact ctatcgatag tttcaaacaa gaaatcgata
    43741 gtacattcag ttatttagaa cgcgttgatt accagcttct tactgaaaaa atgcatacag
    43801 cttcaacaat atatttgtat ggtacagggc gtgcacagtt aaacgttgct tcagaggcac
    43861 agcgtatatt gttaacgtta cataatcatg tcattgtact tcatgatgaa catgaactta
    43921 aaatgatttt gaataagagt gaacctaatg atttattctt tattatttca ttatcaggtg
    43981 aaacacatga attattagaa gtaacaaact tgcttcaact tagacaaaaa tactttattt
    44041 ctgttactac aatgaaagat aatacccttg ctcaaaaagc aaattacaac gtctatgtat
    44101 ccagtaacac attctactta actgatggta cagactattc tagcttcatc agttatcata
    44161 tattctttga aacacttgta agaaaatata atgagtattt actacataat gatatttcaa
    44221 attagaaaaa aggaagttat gatttaatgg ccttgagcct atcataactt ccttttatca
    44281 ttttattgtt gtgttgatgt ttcgataacg tggtacatct tatcaaacat caattcgaaa
    44341 ccatgcacca tggcatcatg atattctttt ttcttttgct tgtattctaa attagtaaat
    44401 cgtctttctt tttcaactaa tgaacgataa taaaatagca tttgggtgcc acctgtttca
    44461 cgttcaaaaa attctacctc aatgacatct tgtgtttcac ttagtccagg cataccgata
    44521 gtcatcttaa cgtattcatc cataactaaa gattcataaa tgccttcaat cacatttact
    44581 ttgccattac gttgttgatc tacaatacga tatttaccgc cttctttaac gtccgcttca
    44641 atctctttat tcgttctggc tgatgtcata aaccattgtt tcaacaaatc tttctttgtc
    44701 caagcttcgt atactaactc tggagaaaat ttataaagct tttcaatttc aacttcgaca
    44761 tgttcattct ctacattaaa ttttgccact gttgtccacc cactttcgct cttactttta
    44821 ttttaacgta tttttgctca gttccaaaca tagatgatca tcatttttaa aagattagcg
    44881 ttatacggtg agtacaacat gatctgttaa tataacaagc caccttactt ggctacatcg
    44941 atatattgtt aagcattaat gtttcatttc ttgactagtg ttctttttta gctttggaaa
    45001 attaaataaa atcgcaacaa gtccgcatac acctaataat ataggataaa tgctgtatgg
    45061 gaataacatt aacggtgaaa taccagctac accagccgct gaaatgactt gcgggctata
    45121 tggtaataaa ccttggaagc agcctccaaa tatatcaaga atacttgctg atttccttga
    45181 atctacatca tattcatctg caatattttt agctaaagga cctgacataa taatagagat
    45241 ggtgttattt gccgtggcaa tatctgcgac acttaccaaa ctagcaattc ctaattctgc
    45301 gccacgcttt gatttcactt tagagcgaac aaattgcaac aaccattcaa taccaccatt
    45361 gtgttgaata atacccacta aaccaccaat tagcaacgca atcatagcaa tatcttccat
    45421 gcttataata cctttggaca ctgcatctag tagccccatc caaccgaatg aaccatctat
    45481 gagaccaatg attccggcta ataatgttcc gccaatcaat acgataatga catttacacc
    45541 taataatgct aataccaata ctaaaatata cggtacaact ttaattagat tataatcata
    45601 gtttttagca tgatttaaag aaatgccatt cgttaagaaa tacagaataa taatcgttaa
    45661 aatagcacct ggcaatacaa ttttaaagtt tactctgaat ttatctttca ttttcgtatg
    45721 ttgtgttcta accgcagcaa ttgttgtatc tgaaatcatt gatagattat cgccgaacat
    45781 tgcacctcca acaactgtag ccattgctag cgcagttggt acatctgtcg cttgtgcaaa
    45841 tccgtaacca acaggtgcta ttgcagcaac agtccctact gacgttccca tagatataga
    45901 aacaaacata caaatcacaa acaatcctac aataattaaa ttttccggga ttaatgatag
    45961 tcctaaatta actgtcgact ttacgccacc cattttttca gctgtatttg aaaatgcacc
    46021 tgctaaaata aaaatcaaca tcattaaaat aatgtttgaa tggcctgcac ctttcgtgaa
    46081 gacctcaact tttttagcaa atgattcttt tcgattcatt aataacgcca caattaccgt
    46141 tatcgtaatt gcaacattta atggcattga agtaaaatca cctgtgataa tacctacgcc
    46201 taaaaacaac gccacaaata ataacaaggg gaataatgcc caagcattgc tctttttatg
    46261 tacttccatc ctttttacct gctttccaat taaaaatacc tctttctcac aaacgatgaa
    46321 gaaagaggtt ttcatgtgct ttacctgctt atcttcaaac cattacggtt actggaattg
    46381 gcacattcga gatgttgccg aggcttcata gggccagtcc ctccacctct ctagataagt
    46441 gatgcttatt tacgtttacg ttacaagata atccttagta cgtcaatcat aaattaatca
    46501 ggagtcgtat aatatttttc ataaacaatc attgctactg taataataat caaaacaata
    46561 atgctaataa caagtaaaag ccaccattta agcattaatg caataaaaat gaacacgata
    46621 gacacactta ctaatattaa tgaaatgact ttaaattgct gaacacgttg cttggagatg
    46681 actttcaact gtttgtttga tggaagcgta tttttaaaat taatacccag tatattttct
    46741 aatatttgaa ccaatacgat acttattgca aatataataa atgatataaa attatagtaa
    46801 cctataatag ttgatccata aataacgatt ccaatgtaga atactcctga gagcacaccc
    46861 aaaaagtaag caacacgttt gtcaaactta atgatatgct ttttaacgtt ttgatgtgta
    46921 agccaaacat tcgaaacaat cgcaaccact acaaacagtg tgaataatat ataaactggc
    46981 aacttttgtt caggaaaaac agtcgctatt ccaaaagcta atactaaaat caaaaataat
    47041 atagctctag atactattaa tgccataata acaacccctt tgtttaatat cgagtttgca
    47101 aatttacgtt tatcagtatt tctatgatca gtacttctac gggcagcgtt tctatgtaat
    47161 tcacatcatc ttaacatata aatacttcgc tatataattg aaaacatatc ctattattct
    47221 ttgtccgttc tgacgtttaa tatctaacct taggcatttc aattgttaat aaatttaact
    47281 ttcttccact aaccgtccct aaacccaatc ccgcaacagt ttttaacttt ttcgttgttg
    47341 tcctgacatc ctcattaaga aagtttattc tgcttaaaac ttataatcca caccctgagc
    47401 aaacgctctt tatgacaggg tattaaaata agccgataaa gatacacacc tttaccgact
    47461 atttaaaata cacttcacta attcatttta atttacttga ttgaagtagc taaattaata
    47521 ttattttgtt caattaaacg cttcatacaa acctaatcta tttgcactcc accgctaaca
    47581 ccgaacactt gtccagttgt ataacttgat tcttctgacg ctaatagcac ataagttcca
    47641 cataactcaa caggttgacc tgcacgacct aaaggtgttt tttgaccaaa tgttgggatt
    47701 ttactttgag gttgtccacc agaaatttgt aatggtgacc agaatggacc aggcgctaca
    47761 cagttcactc taattccttt tggtcctaat tcttctgaaa aacttttagt taatgaaata
    47821 attgctgctt ttgaagcggc ataatcatga agaataggac taggattata gccttgtaca
    47881 gatgatgtcg ttgtaattga cgcacccggt tttaaatatt ccaatgcttt ttgaactgtc
    47941 caaaatagcg gatagacatt cgtttcaaat gtttctgtaa atgcctcagt tgtaaatcca
    48001 tgaatatcat catgatactg ttgatgtcca gcaactaaag taacattatc taagccacct
    48061 aattgttgat atgcatgttc aacaaggtca tagttgaact gctcatctct tatatcacca
    48121 ggaattaaca ctgccttttg accactttct tcaatcactt ggcgtacttc ttgtgcatct
    48181 tgttcttcac tcggaagata gttaatcgct acatctgcac cttctttagc atacgcaatc
    48241 gctgctgcac gccctattgc tgagtcacca cccgtaacta acattttata gccttctaag
    48301 cgttgatgac cttggtaaga cgtttcgcca caatcaggtg ctggcgtcat ttcagattgt
    48361 aaacccggta cctcttgttc ttgtttttca taatctgttg ttttaaattt tgttctagga
    48421 tcttgagctg ccatttttaa catctcctta ttcgcttaat ggttattatt tacccaaact
    48481 tcccaggaac ttaatcatga ttacgctaaa aattactttc ttctttaaaa aacaagctcg
    48541 aattactcat gcaatagtct ctttacaaat tcaacaaaat actcaggtac tttttccaga
    48601 atcctttcat ccggtttata ttgaggatga tgtaaatcat attcactatg agaaccaatt
    48661 aacgcaaata cactaggaaa atgttgacta taacctgaaa aatcttctcc aatcgtaagc
    48721 ggctgttcca tcatttccat cttatatcca acatgttggg ctactgctat tgctttatgc
    48781 gtcaatacct catcattcat cacagcacca ggtaaatgtg tataattcaa attaattttc
    48841 atattatatg cttgagctaa cccgtccgca atattttgta atcgtgtttc tacaagcttt
    48901 cgcaccacag gatcaaaact acgtactgtg ccttgtacat atgcatggtc agcaatgaca
    48961 ttccaagtat taccacatga tatttgccca atggttacta ccgcttcttc aaacgcagat
    49021 agatttctac taactatgga ttgaatacta ttaatcaatt gcgccaacac aataactgga
    49081 tcgttgcatt gttctggctt tgcagcatga ccacccacgc ctttaatatg aaactcaaaa
    49141 cgatctactg ctgatgtaat tgcccctgtt ttgattgcaa atgtacctac cgaacgcgat
    49201 gggtcattat gaaaacccaa tactgcttgt acatctttta atgcatgtgt ttcaataatt
    49261 ttaaaagcgc catgtcctag ttcttctgct ggttgaaaaa tgaatttaac acgcccagta
    49321 agagtgccct caatttcttt taactttaca gctgtagcca aaatactagc catgtgaata
    49381 tcatgaccac acgcatgcat cacaccttca tttttagatt taaaatcctg ttcaacaagc
    49441 tcttgaatcg gtaaagcatc aatgtcagcc cgaacagcta tacaactcgg tccttgtccc
    49501 acttcagcaa caagcccagt cgcaagcggt aagtctaata ttctaatatg atgttctgtt
    49561 aaaatatctt taattttttg cgttgtctta aattctttat cggatagttc tggaaattga
    49621 tgaaaatacc ttctccaggc aacagcttga tcttttaatc ccatcggtca ttccccttcc
    49681 ttaagtcaat gatatgttgt ctaccctacg atgatcatct ttaactatta aacgatgatt
    49741 tcacaacaat gtactcttgt taattacttt cgctaatgat agacaattgt ttaataatat
    49801 cgtaacacta ttgtcaaact attctaactt ttataattaa gaacctatac aaaaacgtgc
    49861 tctcgaatta acttgttttt acaaatcaca aaaagctcta aacattagtg taaaccaacg
    49921 cttagagctt taattacttt atgctttaaa agataatgtg ttatcaacga tgaccttacc
    49981 atttttaata actttttctg cgtgattgat accaaaatga tatggaatat attcatgatt
    50041 tggtgcatcc caaattacta aattagcctt atcacctgtg ttaattgtac ccgcgttaat
    50101 gtctattgct ttagcagcat tgaccgtaac agcattccaa acttcattag gtgatagctt
    50161 taatttcaag gctgcaatcg ccataacaag ttgtaagttg tttgtgacac tactaccagg
    50221 gttataatca gttgctaatg caatcgcacc gttattgtca agcatgcctc ttgcatctgc
    50281 ataatcttct ttacctaaat agaacgtcgt tgcaggtaag aggacagcta cagtatcact
    50341 atttcgcaac ttttcttttc ctttatcact agaagctact aagtggtctg ctgatattgc
    50401 ttgttcatca attgctaatt ccagtccgcc taacggatca atttcatccg catgtatttt
    50461 cactttaaaa cctgcttctt tggctttttg catataatgt tgcgattgtt ctattgtaaa
    50521 tacacctgtt tcacagaaaa tatccgcaaa gtctgcatat tgttttactt ccggaagtaa
    50581 cgcaatcatt tcttctaaaa atgcctcatt tgaacttgcc tctttaggta cagcatgagg
    50641 ccctaggaaa gtatgtttca tgtctaaatc atatttctca gctaaacgat tagacacttt
    50701 caattgcttc agttcatttt ctctatctaa tccataacca ctcttacttt caactgcaag
    50761 cacgccgtgt ttaatcatag taagcaaatc atgctctgct tttttaaaca agtcatcttc
    50821 ggatgtttct ctagtagcat taacggtaga taatatgcca ccacccattt ctaatatttc
    50881 aaggtaagac ttaccttgac gttttaatga catctcatgt tctcgagatc caccaaatgt
    50941 taaatgtgta tgtgcatcta ctaatgctgg ggacactacc ttcccactag catcaatcgt
    51001 ctcagtcgca tcgtagtcat ctgtatgtgt tccagcatat acaattttgc catctttaat
    51061 gacaactgta ccatttttca caacatttaa ttcatctaat tccttaccct tcaaaggttt
    51121 atctgttgat ttcggtaaaa ttaattctgc tatatgatta attattaaat cattcattac
    51181 ttatcacctg ctttatcaat cattggaata tgaatacctt tttctttagc tgtttgaata
    51241 gcgatgtcat agccagcatc aacatgtcgg gcaacaccca tacctggatc agtcgtcaat
    51301 acgcgttcca atcttctttc agcacgctct gatccatctg ctacaacaac catacccgca
    51361 tgaagtgaat atcccatgcc aacaccgcca ccgtgatgga atgaaatcca tgaaccacct
    51421 gcagctgtgt taatgagtgc attcaataca gcccaatcac caaccgcgtc actaccatct
    51481 ttcatacttt ctgtttcacg gttaggacta gcaactgaac cagcatctaa atgatctcgt
    51541 ccaataacaa ttggtgctga aatttcaccg tcacgtacaa gacgatttaa agctaagccc
    51601 attttcgctc gttctccata gcctaaccaa gcaatacgtg atggtagtcc ttgatatgaa
    51661 attttttctt cagctaaatc aagccatctt aataactttt cattttctgg gaaaagtttg
    51721 cgcatttctt catccgcacg ctcgatatct tttggatcac cactcaacgc agcaaagcgg
    51781 aatggccctt taccttcaca gaataatggt ctaatgtaag ctggtacaaa gcctgggaag
    51841 tcaaaagcat ttttcactcc gttattgaag gctacttgac gaatattgtt accataatca
    51901 aatgctacag cgccacgttt ttggaattca agcattaatt caacatgctt tgccattgaa
    51961 gcttgtgaca gttcaacata ttttttcgga tctttttcac gcaatacttt cgcttcttct
    52021 acagagtatc cttgtggcac atatccattt agcggatcat gtgcacttgt ttggtcagta
    52081 ataatgtcaa ttttaaatcc tttttctaga atcgcttgat ggatgtctac agcatttcca
    52141 actaacccga ttgataatcc ttctccacgt tctttcgcct cttctgctaa ttttaatgct
    52201 tcatctaaat cagctgtttt aacatcacag tatttcgtat caattcgctt atcaacacgt
    52261 gtttcatcaa catccacgca aattgctacc ccatgattca tagtaattgc taacggttgc
    52321 gcaccaccca taccacctaa acctgctgtc agtgtaacag tgcctgctaa atctccatta
    52381 aagtgttgat tacctagctc ggcaaatgtc tcataagtac cttgcacaat accttgagaa
    52441 ccaatatata tccaactacc ggctgtcatc tgtccataca tgattaaacc ttttttatct
    52501 aattcattaa aatgatccca gtttgcccat tcaggcacta atactgaatt tgaaattaat
    52561 acacgtggcg cttcttcatg tgttttaaat acagcaactg gctttcctga ttgtactaac
    52621 attgtctcat ctgattctaa ttctcgtaac gttttctcta ttgcttcaaa agcttcccaa
    52681 ttacgtgctg cttttccaat accaccataa acaactaaat cttctggtct ttcagcaact
    52741 tctgggtcta aattgttgta taacattcta agtactgctt cttgttccca acctttacac
    52801 tcaatactta aacctttttt tgcttgaatt tttctcataa aattcgctcc tgttcttttt
    52861 agaagttaat tccactaaat ttaaaacgct tacattatta tcttcaatat tcattatagt
    52921 atgttaaaat atagccaaca aatataaata aactaattat ccatagcttg aatctataaa
    52981 taaaaggagc aaaacacatg aaaattattc agttagaata tttcttggct atcgtgaaat
    53041 ataatagttt tactaaagct gcacaatttt tacatattag ccagccatct ttaactgcta
    53101 cgattaaaaa aatggaagca gatttaggtt atgacttatt tacacgttca acaaaagaca
    53161 tcaagattac cgaaaaagga atacagtttt atcgttatgc gagcgaatta gttcaacaat
    53221 atcgatccac gatggaaaaa atgtatgatt taagcgttac atcagaacca aggataaaaa
    53281 ttgggactct tgaatctacg aatcaatgga ttgcgaattt aattcgaaag caccattccg
    53341 actaccctga acagcaatat cgtttatatg aaatacatga caaacatcaa tctatagagc
    53401 aattactgaa ttttaatatt catttagcta taacaaatga aaaaataacc cacgaagata
    53461 taagatccat tcctttatat gaggaatctt acattttatt agcacctaaa gaaacattta
    53521 aaaatcaaaa ttgggtagat gttgaaaatt tgccactcat attgccaaac aaaaattctc
    53581 aagtgcgcaa acacttagat gactatttta atagaagaaa tattcgtcca aatgtcgttg
    53641 tagaaacaga tcgattcgaa tcagcagttg gatttgttca tctcggctta ggttacgcta
    53701 tcattccgag attttattac caatcatttc acacgtccaa tttagaatat aaaaaaattc
    53761 gaccaaactt aggccgaaaa atttatatca attatcataa aaagcgtaaa cactccgaac
    53821 aagtacatac attcgtacaa caatgccaag attatttata tggactttta gaggc
//
LOCUS       DAPSKH010000008        53759 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPSKH010000008 DAPSKH010000000
VERSION     DAPSKH010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 53759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 53759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..53759
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.008"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(541..1476)
                     /locus_tag="RPH49_000599"
     CDS             complement(541..1476)
                     /locus_tag="RPH49_000599"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HDY5123789.1"
                     /translation="MYKQGEPNLWTGRLDSETDPKKFRHFQTVTFEDLSKLEKSSMPS
                     GVGILGYAVDKGVALNKGRIGAKEGPDAIKQAFAGLPDLNQCETLVDYGNVYHDHEEL
                     IDTQKEFAMLAAKSIANHRQTFLLGGGHDIAYAQYLATRKVYPTQSIGVINIDAHFDT
                     RAEQQSTSGTSFRQILEEDENTDYLVLGIAQGGNTQSLFDYAKEKKIDYVFADELLSH
                     VSPTIKDMIERFVHEHDVIMFTICMDVIDSAFAPGVSAPAVLGLYPHTVLELAKRIIP
                     SDKVSSVSIAEMNPTYDADNRTAKLVANLVHHFLK"
     gene            1766..3022
                     /gene="sdpC"
                     /locus_tag="RPH49_000600"
     CDS             1766..3022
                     /gene="sdpC"
                     /locus_tag="RPH49_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease SdpC"
                     /protein_id="HDY5123790.1"
                     /translation="MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFE
                     VTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLVILIIGMYSFN
                     TFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVG
                     LMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLI
                     FLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHV
                     NDDKETNHTEAEKSSSNIKNAEKTGVATASTVGIAKNDTENTVADEPSIHEGTEKTEA
                     QHHIDNQTESNHDEDHDITSESVESAEPVKHAPQSDDLTNDSNEDEKQSLKEPATYKE
                     DRRSSVVIDAEKHIEKTEEQSSDKNK"
     gene            complement(3088..3774)
                     /locus_tag="RPH49_000601"
     CDS             complement(3088..3774)
                     /locus_tag="RPH49_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 5-phosphate isomerase A"
                     /protein_id="HDY5123791.1"
                     /translation="MKDVKALKLMTLNDVLSQINGDMTLGIGTGSTMELLLPQMAQLI
                     KERGYNITGVCTSNKIAFLAKELGIKICEINDVDHIDLAIDGADEVDPSLNIIKGGGG
                     ALFREKVIDEMASRFVVVVDETKMVQYLGEMFKLPVEVDKFNWYHILRKIESYADIKV
                     ERRVNEDVAFITDNGNYILDCKLPKGIDPYKFHEYLIHLTGVFETGYFLDMADQVIVG
                     TQEGVKILEK"
     gene            3948..4601
                     /locus_tag="RPH49_000602"
     CDS             3948..4601
                     /locus_tag="RPH49_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MOSC domain-containing protein"
                     /protein_id="HDY5123792.1"
                     /translation="MISIHAISTGKIQDLPYSSKRPMRSALDKTKISQTTWLSSTGFT
                     GDEQAYKDHGGPHKAVCGFSKHNYALYQDDLPSLPTHAMFGENLTFDYLDESDVYFGN
                     QYRLGYALIEVSEIREPCWKIQAKYNIPDLVKRMSTSGKTGFYFRVLKQGYVSPNDQL
                     YLIQEAPIEHRLSVQQLNDLYYNDRQNQDLLRYALNNPFLSPTRRDKLQKMYNRTLK"
     gene            complement(4835..5854)
                     /locus_tag="RPH49_000603"
     CDS             complement(4835..5854)
                     /locus_tag="RPH49_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDY5123793.1"
                     /translation="MIVEVEHQRQGVDLIKIDNDETKIIFTNYGARVVSWKYHDNNIV
                     LGNVVEADEFYHSNPFKFGASIGRYSGRIDNAKFKLKGKEYQLEKNNGEHHLHGGCHG
                     LDNKLFDYEIRNEIAQIKVIFKTVLKSADDHFPGDIDVTITHIYDADHQWSIEYEAVA
                     SEDTLFSPTNHVYFNLNRDNNVVDNHRISSNQLDMYVLDERNIVTGDILDLHEVFEDN
                     KIKLSDIFTSQHAQLSQQMIRFGGLDHPFTVGEHKMYVENHEFMLEVDTDMPHVVFFT
                     FNQPDEWDSPFNIYKPHSGFTLETQFLPNDINLYGDKAPSILKAGEVFNSKTSFRIEE
                     KVEND"
     gene            complement(5884..6210)
                     /locus_tag="RPH49_000604"
     CDS             complement(5884..6210)
                     /locus_tag="RPH49_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDY5123794.1"
                     /translation="MLYPIFIFILAGLCEIGGGYLIWLWLREGQSSLVGLIGGAILML
                     YGVIATFQSFPSFGRVYAAYGGVFIIMSLIFAMVVDKQMPDKYDVIGAIICIVGVLVM
                     LLPSRA"
     gene            complement(6259..6444)
                     /locus_tag="RPH49_000605"
     CDS             complement(6259..6444)
                     /locus_tag="RPH49_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123795.1"
                     /translation="MYLKNKIDESDTHLSYKMMMKACYSYFFIFSYRIMSKKVYNMNV
                     KTNFLKWECEVRRNVNK"
     gene            complement(6428..7660)
                     /locus_tag="RPH49_000606"
     CDS             complement(6428..7660)
                     /locus_tag="RPH49_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123796.1"
                     /translation="MHKFWATFTLTYIKKIKAKSFVIFMIIIAALMIGLSNIDKIINM
                     FDDGPDKIGVAAPNEQIYKVFKQQANTFHSDAKFTKVSIEDAEKEVKKHKLDKAYIIK
                     VNQNRTLQGTIISEKRVSHEDSQKVQALLTAIQTNMVAGELNINKEDLQKLQAQSKVD
                     NKVISNDEVDKVSEGQKIFNYALAYGIIFLMFFIVLNYASQIAMEIASEKTSRVIEMI
                     ITSISPIQHIFAKILGVIAVAVTQIILIVLMAVICIFAFDLKDLLQGFNVEMNQLSWQ
                     IIIVGIISSIVGIMAYVLLAAILGSLTSRIEDLNQSLMPLTLLGMIAFYIAIFTINNP
                     DGQLALITSYIPFLAPFQLVVRAQTSGLQIHEVILSSLISIVMVAVLIWIAIKTYKDS
                     VLTFERGLFNSMKRVFKK"
     gene            complement(7653..8552)
                     /locus_tag="RPH49_000607"
     CDS             complement(7653..8552)
                     /locus_tag="RPH49_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123797.1"
                     /translation="MGLVIEHVTKRFGKMTAVNDISLELESGKMLGFLGRNGAGKTTT
                     FRMILGLSEPTEGHITYNGKKLDKTMYNRIGYLPEERGLHGKLTVEEELKYLATLKGM
                     SKTEIQQQISYWLERFDITENRKKRIDSLSKGNQQKIQLLASMLHKPELLILDEPFSG
                     LDPVNVELLKEAVKDLNDWGSTIVYSSHRMEHVEELCDDVCILDKGQLVVSGDINHVR
                     ASNGNKKVVIESETTLPDLTNIRGIIHSENMKQGLQLTIENEDVAKDIYQVVAHQGYV
                     KRFQVVEPSLQDIFIEKVGGKDA"
     gene            complement(8784..9404)
                     /locus_tag="RPH49_000608"
     CDS             complement(8784..9404)
                     /locus_tag="RPH49_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDY5123798.1"
                     /translation="MEQLPQVGFMKSFVLFWKNYVNFKGRSRRSEYWYMMLWHLIFMV
                     PAVCVLIISLFLFFISIAADNETLIVMSILMIILTSVYTFVYSLATFIPNLALCVRRF
                     HDISRTMLFPMIMTAFSIIFYIVLQIIDSYYDSDFTLMPMGLNILLVFLYFVYLSLTI
                     VMIVFLCFDSKPANKYGESPKYPSSIKNQPVTSETPKTPGETDNQL"
     gene            9803..10411
                     /locus_tag="RPH49_000609"
     CDS             9803..10411
                     /locus_tag="RPH49_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDY5123799.1"
                     /translation="MDFVNNDTRQIAKNLLGVKVIYQDTTQTYTGYIVETEAYLGLND
                     RAAHGYGGKITPKVTSLYKRGGTIYAHVMHTHLLINFVTRSEGIPEGVLIRAIEPEEG
                     LSAMFRNRGKKGYEVTNGPGKWTKAFNIPRAIDGATLNDCRLSIDTKNRKYPKDIIAS
                     PRIGIPNKGDWTHKSLRYTVKGNPFVSRMRKSDCMFPEDTWK"
     gene            10748..11956
                     /gene="gltS"
                     /locus_tag="RPH49_000610"
     CDS             10748..11956
                     /gene="gltS"
                     /locus_tag="RPH49_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDY5123800.1"
                     /translation="MIELNAITTLCLACILYLLGKAIVNHVNFLKRICIPAPVIGGLI
                     FAILVATLDSFGMVKIKLDASFIQDFFMLAFFTTIGLGASLKLFKLGGKVLLLYFMFC
                     AIISVIQNIVGVSLAKVLNIKPLLGLTAGSMSMEGGHGNAAAYGKTIQDLGIDSALTA
                     ALAAATLGLVFGGLIGGPVVKFLIKRYNLKPQHSDDTFKDYSQVAYNEHLHSKFNATE
                     VFFIQFTIVVFCMAVGSYFSHLFTSQTGINVPIYVGSLFVAVIVRNISESFNFNIVDL
                     KITNQIGDVALGIFLSLALMSIQLIEIYKLAIPLIIIVLVQVVVMILFAVLILFRGLG
                     KDYDAAVMVGGFIGHGLGATPNAMANLDVITKKYGNSPKAYLVVPIVGAFLIDLIGVI
                     VIMGFIQWFS"
     gene            complement(12004..13053)
                     /locus_tag="RPH49_000611"
     CDS             complement(12004..13053)
                     /locus_tag="RPH49_000611"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDY5123801.1"
                     /translation="MSDFQREQRKNEHVEIAMAQSDAMHSDFDKMRFVHHSIPSINVN
                     DIDLTSQTPDLTMAYPVYINAMTGGSEWTKNINEKLAVVARETGLAMAVGSTHAALRN
                     PRMAETFTIARKMNPEGMIFSNVGADVPVEKALEAVELLEAQALQIHVNSPQELVMPE
                     GNREFVTWLDNIASIVSRVSVPVIIKEVGFGMSKELMHDLQQIGVKYVDVSGKGGTNF
                     VDIENERRANKDMDYLSSWGQSTVESLLETTAYQSEISVFASGGLRTPLDAIKSLALG
                     AKATGMSRPFLNQVENNGIAHTVAYVESFIEHMKSIMTMLDAKNIDDLTQKQIVFSPE
                     ILSWIEQRNLNIHRG"
     gene            complement(13084..14031)
                     /gene="corA"
                     /locus_tag="RPH49_000612"
     CDS             complement(13084..14031)
                     /gene="corA"
                     /locus_tag="RPH49_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDY5123802.1"
                     /translation="MALTIRYQTTYEPFKVVDDIKEIPKDATIVWYDFDEPNEQENEW
                     FKAHFNFNDLEVDDAINGMPRAKYKSYKDYQYLVFHSIMGSNYSPIALNIFIQDNVLV
                     TYHHQTLESLNKVVYKYMNTLDAELDCADVVILILDMMVDKYFNFVYALEDSVYHFED
                     RHVDDRFNKMVMDSVFKLRSDLIKVKRVLFPMQELIDTMKQNGDLIIDNKHSLYIQHI
                     DDHLIKQRNIIRTAQEMTNEIRENFESYTSFRMNSIMQVLTLVSVIFSPLTFIAGIYG
                     MNFVNMPALHLHYGYYICLAVMFVIAVVLIIFFRRKKWF"
     gene            14128..14619
                     /locus_tag="RPH49_000613"
     CDS             14128..14619
                     /locus_tag="RPH49_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDY5123803.1"
                     /translation="MVIIKQLFTHTQTVTSEFIDHNNHMHDANYNIIFSDVVNRFNYS
                     HGLSLKERENLAYTLFTLEEHTTYLSELSLGDVFTVTLYIYDYDYKRLHLFLTLTKED
                     GTLASTNEVMMMGINQHTRRSDAFPESFSTQIAHYYKNQPTITWPEQLGHKIAIPHKG
                     ALK"
     gene            14616..15035
                     /locus_tag="RPH49_000614"
     CDS             14616..15035
                     /locus_tag="RPH49_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123804.1"
                     /translation="MTDALQQKIHIELLDLLDDVKFELTELNAQKGLYINGPANQLLK
                     RGVHMAYVQGQKQAIDNIMTIVEQQLEDQHFLEHYDKFQNEVAHRNYDKTANFAELSD
                     IPRQFDNFLDQFYQIKGQYFIITHINTLIGDFHSEAH"
     gene            complement(15141..16061)
                     /locus_tag="RPH49_000615"
     CDS             complement(15141..16061)
                     /locus_tag="RPH49_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5123805.1"
                     /translation="MIRNRVMNSVVNKYLLHNRSIMFKNDQDVERFFYKRKIENRKKH
                     KQPSTLNVKANLEKLSLDDMQVFRFNFRHQIDKKILYIHGGFNALQPSPFHWRLLDKI
                     TLSTLYEVVLPIYPKTPEFHIDDTFQAIQRVYDQLVSEVGHQNVVVMGDGSGGALALS
                     FVQSLLDNQQPLPNKLYLISPILDATLSNKDISDALIEQDAVLSQFGVNEIMKKWANG
                     LPLTDKRISPINGTIEGLPPVYMFGGGREMTHPDMKLFEQMMLQHHQYIEFYDYPKMV
                     HDFPIYPIRQSHKAIKQIAKSIDEDVTQNN"
     gene            16269..16907
                     /locus_tag="RPH49_000616"
     CDS             16269..16907
                     /locus_tag="RPH49_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123806.1"
                     /translation="MTNPNQRLEPFDETFQQPNIHRGKRYGKKKRSLVSMIIQIIVVI
                     LTAIAGYSMWKQPIFNIVFTKESVDFDGIKNFNETIGKMHQLNINLGNINDLQQGIDR
                     LILVFNGFFILCIVSLVITILTIVFNRTVLKVVNILVLTIMLVITLYFSYIIKALAQE
                     IADVFKKYYVNVPPDQVITEADAIHNGIILLGCSIGLLVISLFFRNRMPRLK"
     gene            complement(17154..19091)
                     /locus_tag="RPH49_000617"
     CDS             complement(17154..19091)
                     /locus_tag="RPH49_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHA2 family efflux MFS transporter permease
                     subunit"
                     /protein_id="HDY5123807.1"
                     /translation="MTTTFIISYIVLALIIVGVINLLLIRSRRKAKRQQKEQHFATRQ
                     SNQSKFKASDLDRTTDQSSQHTAREEARIDNQDNQNQVSLNKQTEGSEQNQASFTDNN
                     ESDEEVYAAKNPKSEEYKVNEKIKKEHKNFIFGEGVSRGKILAALLFGMFIAILNQTL
                     LNVALPKINTEFNISASTGQWLMTGFMLVNGILIPITAYLFNKYSYRKLFLVALVLFT
                     IGSLICAISMNFPIMMVGRVLQAIGAGVLMPLGSIVIITIYPPEKRGAAMGTMGIAMI
                     LAPAIGPTLSGYIVQNYHWNVMFYGMFIIGIIAILVGFVWFKLYQYTTNPKADIPGII
                     FSTIGFGALLYGFSEAGNKGWGSVEIETMFAIGIIFIILFVIRELRMKAPMLNLEVLK
                     FPTFTLTTVINMVVMMSLYGGMILLPMYLQNLRGFSALDSGLLLLPGSLIMGLLGPFA
                     GKLLDTIGLKPLAIFGIAVMTYATWELTKLNMDTPYMTIMGIYVLRSFGMAFIMMPMV
                     TAAINALPGRLASHGNAFLNTMRQLAGSIGTAILVTVMTTQTTQHLSAFGEELDKTNP
                     VVQDHMRELASQYGGQEGAMKVLLQFVNKLSTVEGINDAFIVATIFSVIALILCLFLQ
                     SNKKAKATAQKIDADNSINHE"
     gene            complement(19104..19751)
                     /locus_tag="RPH49_000618"
     CDS             complement(19104..19751)
                     /locus_tag="RPH49_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDY5123808.1"
                     /translation="MKKMILINVITVVVLLAIGIAGFYFWNKTTSYITTDNAKVNGDQ
                     IKIASPASGQIKSLNVKQGDKLDKGDKVATVTVQGQDGETKDMELKMPQKGTIAKLDG
                     MEGSMVQAGNPIAYAYNLDDLYVTANIDEKDIKDVEVGKDVDVTIDGQKASVKGKVDS
                     IGKATAASFSLMPSSNSDGNYTKVSQVIPVKITLDSEPSKQVVPGMNAEVKIHKN"
     gene            19872..20426
                     /locus_tag="RPH49_000619"
     CDS             19872..20426
                     /locus_tag="RPH49_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001661235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5123809.1"
                     /translation="MKRQAKIEIQNALVDLMAEYPFQEISTKMICAYCNINRSTFYDY
                     YKDKFDLLDTINSKHKEKFQFLLSALHHNFENIKQDKLKLYKFFIIIAKYIKRNEQFF
                     KDILVTYPMKTLFIDYINLARDYYQQIMNDYSTTVTNKQLYVTYIIGGQAGVFINWLS
                     NGCNESPEEVADILLANTIKLQNQ"
     gene            complement(20653..21861)
                     /locus_tag="RPH49_000620"
     CDS             complement(20653..21861)
                     /locus_tag="RPH49_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HDY5123810.1"
                     /translation="MNDLKRFNKRSPIFIIILGSLTAIGALSIDMFLPGLPDIRHDFQ
                     TTTSNAQLTLSMFMIGLAFGNLFAGPISDSNGRRKPLIIAMIIFTLASLGIVFVHNIW
                     LMIALRFLQGVTGGAAAVISRAIASDMYSGNELTKFMALLMLVNGIAPVVAPTIGGII
                     LNYSVWRMVFVILTIFGFVMVIGSLLKVPESLTVTNRESSSGLKTMFKNFKILLKTPR
                     FVLPMLIQGMTFVILFTYISASPFIIQKIYGMTAIQFSWMFAGIGITLIISSQLTGYL
                     VDFIDSQKLMRVMTMIQIIGVILVTIVLLNHWNFWILAIGFIILIAPVTGVATLGFTI
                     AMDESSSGRGSSSSLLGLVQFLFGGIASPLVGVKGEDNPIPYIIIIIATAVILIILQI
                     YNMKVFKTNR"
     gene            complement(21971..22098)
                     /locus_tag="RPH49_000621"
                     /pseudo
     CDS             complement(21971..22098)
                     /locus_tag="RPH49_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501095.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(22129..23511)
                     /locus_tag="RPH49_000622"
     CDS             complement(22129..23511)
                     /locus_tag="RPH49_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDY5123811.1"
                     /translation="MKSCPKCGQQAQDDVQICTQCGHKFDSRQALYRKSTDEDIQTNN
                     IKMRKMVPWAIGFFILILIIILFFLLRNFNSPEAQTKILVNAIENNDKQKVATLLSTK
                     DNKVDSEEAKVYINYIKDEVGLKQFVSDLKNTVHKLNKSKTSVASYIQTRSGQNILRV
                     SKNGTRYIFFDNMSFTAPTKQPIVKPKEKTKYEFKSGGKKKMVIAEANKVTPIGNFIP
                     GTYRIPAMKSTENGDFAGHLKFDFRQSNSETVDVTEDFEEANITVTLKGDTKLNDSSK
                     KVTINDREMAFSSSKTYGPYPQNKDITISASGKAKDKTFTTQTKTIKASDLKYNTEIT
                     LNFDSEDIEDYVEKKEKEENSLKNKLIEFFAGYSLANNAAFNQSDFDFVSSYIKKGSS
                     FYDDVKKRVSKGSLMMISSPQIIDAEKHGDKITATVRLINENGKQVDKEYELEQGSQD
                     RLQLIKTSEK"
     gene            complement(23751..24206)
                     /locus_tag="RPH49_000623"
     CDS             complement(23751..24206)
                     /locus_tag="RPH49_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5123812.1"
                     /translation="MVKHLQDHIQFLEQFINNVNALTAKMLKDLQNEYEISLEQSNVL
                     GMLNKEPLTISEITQRQGVNKAAVSRRIKKLIDAKLVKLDKPNLNIDQRLKFITLTDK
                     GRAYLKERNAIMTDIAQDITNDLNSEDIENVRQVLEVINHRIKTYSNHK"
     gene            24401..25369
                     /locus_tag="RPH49_000624"
     CDS             24401..25369
                     /locus_tag="RPH49_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDY5123813.1"
                     /translation="MLLNLLLLFILIVICPLIFNYTLTLNLTCYILVVISIFLSLIYS
                     IMTYTFPWSMFITFIIISIIMLFKHRYLFSHTSSRLFIKKLLSFSYKFVLYTSALLFI
                     STIQSPIVKGLSMWLAILCLSLLLTFICYLVWTVSYRHRSYNKEVDIIIVLGAGIFTE
                     FVTPMLAARLDRALDIYQQQVSATKIIVSGGQGPDEPIPEALAMQRYLIAHGVDKTDI
                     LMESHSINTYTNFLYSKQIINNLYHEAVKIVCVTSQFHVLRALRLAQKLGLSIDGVGS
                     HTPYHFFLHVLIKDYLGVMYQYRLLLTLYCSSSWFICLYAAFIYNS"
     gene            complement(25600..26265)
                     /locus_tag="RPH49_000625"
     CDS             complement(25600..26265)
                     /locus_tag="RPH49_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123814.1"
                     /translation="MALVVKDIVKNFGEGLSETKVLKGINFEVEQGEFVILNGASGSG
                     KTTLLTILGGLLSQTSGTVLYNDAPLFDKQHRPSDLRLEDIGFIFQSSHLVPYLKVIE
                     QLTLVGQEAGMTKQQSSTRAIQLLENIGLEDRLNVYPHQLSGGEKQRVAIMRAFMNNP
                     KIILADEPTASLDADRATKVVEMIRQQIKEQQMIGIMITHDRRLFEYADRVIELEDGK
                     ITD"
     gene            complement(26265..27320)
                     /locus_tag="RPH49_000626"
     CDS             complement(26265..27320)
                     /locus_tag="RPH49_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123815.1"
                     /translation="MKLAIKEIMFYKFRYILITLIILLLSIMVLFISGLAQGLGRENI
                     SLFEHFDNDEYVVQKMKEPQIEKSQLSDTQQNQIKKVIHQEPYKMNIQTLKLSNKEQD
                     VITMNDVKQQRIQLKKGDYPKNAHEVAINDKLAADNIRVGDRLHFKNNSTSYRVSGIL
                     NDTMYAHSSIVLLNDNGFNALNKVNTAFYPVKNLTQQQRDELNKINDVQVVSEKDLTG
                     NIASYQAEQAPLNMMIVSLFTITAIVLSAFFYVMTIQKISQIGILKAIGIKTRHLLSA
                     LVLQILTLTIIGVGIAVIIIVGLSFMMPVTMPFYLTTQNILLMVGIFILVAILGASLS
                     FVKLFKVDPIEAIGGAE"
     gene            27456..28130
                     /gene="hssR"
                     /locus_tag="RPH49_000627"
     CDS             27456..28130
                     /gene="hssR"
                     /locus_tag="RPH49_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding heme response regulator HssR"
                     /protein_id="HDY5123816.1"
                     /translation="MVQCLVVDDDPRILNYIASHLQTEHIDAYTQPSGEAALKLLEKQ
                     RVDIAVVDIMMDGMDGFQLCNTLKNDYDIPVIMLTARDALSDKERAFISGTDDYVTKP
                     FEVKELIFRIRAVLRRYNINSNSEMTIGNLTLNQSYLELQVSNKTMTLPNKEFQLLFM
                     LAARPKQIFTREQIIEKIWGYDYEGDERTVDVHIKRLRQRLKKLNATLTIETVRGQGY
                     KVENHV"
     gene            28123..29496
                     /gene="hssS"
                     /locus_tag="RPH49_000628"
     CDS             28123..29496
                     /gene="hssS"
                     /locus_tag="RPH49_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme sensor histidine kinase HssS"
                     /protein_id="HDY5123817.1"
                     /translation="MFKTLYARIAIYSITVILFSALISFVLTNVYYHYNLKASNDAKI
                     MKTLKEARQYEQSAKPTHIQQYFKHLGQMNYQIMTVDQKGHKTFYGEPFREDTLSQNA
                     INNVLNNKDYHGIKDKPFALFVTGFFDNVTDNTVGINFKTKDGSIAVFMRPDIGETFS
                     EFRTFLAVLLMLLLFISISLVIASTYSIIRPVKKLKLATERLIDGDFETPIKQTRKDE
                     IGTLQYHFNKMRESLRQVDQMRQHFVQNVSHEIKTPLTHIHHLLSELQQTSDKTLRQQ
                     YINDIYTITTQLSGLTTELLLLSELDNHQHLLFDDKIQVDQLIKDIIRHEQFSADEKS
                     LIILADLESIDFLGNQRLLHQALSNLLINAIKYTDVGGAIDIALQHSHNNIIFTISND
                     GSPISPQAEARLFERFYKVSKHDNSNGLGLAITKSIIELHHGTIQFTQSNEYVTTFTI
                     TLPNNSH"
     gene            29659..30102
                     /locus_tag="RPH49_000629"
     CDS             29659..30102
                     /locus_tag="RPH49_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5123818.1"
                     /translation="MMKLNLFINATETESYIDIHAPKMNDHVQSIINAVNDLDKSHTL
                     VGYIDKEIHIINVSDVITFQVINKNVTAITSNQKFKLKLRLYELEKQLPQHFIRISKS
                     EIVNKYYIEKLLLEPNGLIRMYLKDAHYTYSSRRYLKSIKERLSI"
     gene            30099..30554
                     /locus_tag="RPH49_000630"
     CDS             30099..30554
                     /locus_tag="RPH49_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HDY5123819.1"
                     /translation="MKNLKNSLFISLIIGLSLSLFFSMLFADGKYYPLNPQSTIGILY
                     YNHFTETTVMLISIILWLLIGVVFFLGDFIFKYTDWGITKATIVHFITTYVGFLPLAI
                     LAGWFPLTINSLIIFTIIFIVVYTLIWIIQFFKNKNYVDTINEQLKQLK"
     gene            complement(30731..31294)
                     /locus_tag="RPH49_000631"
     CDS             complement(30731..31294)
                     /locus_tag="RPH49_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000372852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDY5123820.1"
                     /translation="MDQTAFTDSRVTKTINRIHDGMVNLLKMKAYNDITVKDICEKSQ
                     ISRTTFYTHYKTKDDFIYSYLNTLLKVAKKKFIKERPMTQAVFFKRMIYYWLSEGQLI
                     LMLLGDESAYKLHQVIKKSLQQRIEINVVPVLNTKMLTTKEKYFLLIFMSNAIIGVLQ
                     DWVKRGYKESPKEVAEIMNKIFENAFR"
     gene            31428..32156
                     /locus_tag="RPH49_000632"
     CDS             31428..32156
                     /locus_tag="RPH49_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5123821.1"
                     /translation="MDATIAKLDKVVKTYNKHHVLNEISMSINKGELLGLIGPSGSGK
                     TTTIKCLLGMEKVDSGSAEIFAHKMPNSKALNRLGYMGQTDALYENLTAYENLEFYGR
                     LSGLKGNVLKDNIEKNIVLVNLEQALNKKVAQFSGGMKRRLSLAITLLAEPELIILDE
                     PTVGIDPKLRQQIWQQFKQMTKDGKSVVITTHVMDEAERCDKVGLIVDGRIFAIDTPT
                     NLKQRFNVDTIEAVFIKAEEVRQS"
     gene            32153..33235
                     /locus_tag="RPH49_000633"
     CDS             32153..33235
                     /locus_tag="RPH49_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000696075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5123822.1"
                     /translation="MKILAIVKRVLKEMLRDKRTLALMFLAPILILTLMYFIFNGDEN
                     DLKIGIDTSVSSNITKQLPSSDIKTQTFHSHENIRSKIENNHLDGYIYQENQTLHVIY
                     TNEDPNKSNMIKQMIGKAIQQDKISSIKHLIEKAPPTMKAPNKQDIKISHSYLYGNSD
                     STYFDKMFPILMGFFVFLFVFLISGIALLRERTTGTLERVLSTSIRRSEIVLGYLIGY
                     GIFAIIQTLIIVLFSIYLLNINLAGSLWYVILINICLAITALSMGIFISTFANSEFQM
                     IQFIPLVAVPQVFFSGIFPLENMPDWLGNIGYLFPLRYAGDALTNIMIKGQGWSNIWF
                     DLLILMIFIIVFIILNIVGLKRYRQV"
     gene            complement(33362..34840)
                     /gene="mqo"
                     /locus_tag="RPH49_000634"
     CDS             complement(33362..34840)
                     /gene="mqo"
                     /locus_tag="RPH49_000634"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDY5123823.1"
                     /translation="MTTQHSKTDVILIGGGIMSATLGTLLKELSPEKNIKVFEKLAQP
                     GEESSNVWNNAGTGHSALCELNYTKEGKDGTVDCSKAIKINEQYQISKQFWAYLVKTG
                     QLDNPDRFIQAVPHMSFVIGEDNVAFIKSRVATLKKSVLFEKMKLSQDEEEMKSWVPL
                     MIEGRKSDEPIALTYDETGTDVNFGALTAKLFDNLEQRGVEIQYKQNVLDIKKQKSGA
                     WLVKVKDLETNETTTYESDFVFIGAGGASLPLLQKTGIKQSKHIGGFPVSGLFLRCTN
                     QEVIDRHHAKVYGKAAVGAPPMSVPHLDTRFVDGKRSLLFGPFAGFSPKFLKTGSHMD
                     LIKSVKPNNIVTMLSAGIKEMSLTKYLVSQLMLSNDERMDDLRVFFPNAKNEDWEVIT
                     AGQRVQVIKDTEDSKGNLQFGTEVITSDDGTLAALLGASPGASTAVDIMFDVLQRCYR
                     DEFKGWEPKVKEMVPSFGYRLTDHEDLYHKINEEVTKYLQVK"
     gene            complement(35221..36819)
                     /locus_tag="RPH49_000635"
     CDS             complement(35221..36819)
                     /locus_tag="RPH49_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDY5123824.1"
                     /translation="MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITT
                     LVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQ
                     DSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLV
                     ANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGF
                     RGVKETLPAILVVSITYTLTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIY
                     RVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKY
                     NLPGTVSEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKEL
                     WLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNN
                     NSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELL
                     KMTLKYSVCLLIFICIWTFILSLL"
     gene            37136..38809
                     /locus_tag="RPH49_000636"
     CDS             37136..38809
                     /locus_tag="RPH49_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDY5123825.1"
                     /translation="MIKQINVSNMQKFESQLMKAQSEGYTHVVPYANEIMIYQSMLDA
                     VQLYPKSIVVDYTVDGQYKNDCHYFGQSTINIADWAQNNNYYPNLIYAIQQTLDLIHY
                     YSVETIFDLALLTLLKGDLSIDGHVVFDFKAPLATSASIWETIKTIEDFDMMSQFYLN
                     KMAYIDHHPIPFRNLFIEDSEQLNSPDNWLYSTKFMLPKWLYKIAKQRADNKQLQNFG
                     LYTKQPNVLKDHIVFIGDHHQYIGNSKYLFTYFVKHNPMTACYFVTDDRRGPHFISPK
                     SEKADELINSARVVLVENDIPETLQPNGTLIQLHQGTPIMQLFLDSKEPIKNIETPFY
                     RAKRYNRWLQFDYVIHSADDISHFYQTAFPSHQANVLAYGNPKHQYLLQKRNESTTQQ
                     QYKKSFKINDQKPVLLYAPIGLVSAQQLPLSDALFKAYHVVVQGIDETMLPEEAIVAP
                     KYLSAQDLILMSDVVITDYSNIIFNAMAIDKSVALYTPNHSQYIESQGVNEDIWRHLS
                     KIWYTDRQLLINNLISQAIPVIKYPQIQHKEQPLESISQLILSKMTSNQ"
     gene            complement(38965..39594)
                     /locus_tag="RPH49_000637"
     CDS             complement(38965..39594)
                     /locus_tag="RPH49_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123826.1"
                     /translation="MKRLVTGLLALSLFLAACGQDSDQQKDSNKEKDDKAKTEQQDKK
                     TNDSSKDKKDNKDDSNDVNKDNKDNSANDNQQQSNSNATNNDQNQTNNNQSSNNQANN
                     NQKSSYVAPYYGQNAAPVARQIYPFNGNKTQALQQLPNFQTALNAANNEANKFGSNNK
                     VYNDYSIEEHNGNYKYVFSFKDPNANGKYSIVTVDYTGQAMVTDPNYQQ"
     gene            complement(39908..40423)
                     /locus_tag="RPH49_000638"
     CDS             complement(39908..40423)
                     /locus_tag="RPH49_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123827.1"
                     /translation="MAGIIKEISKQDAGELVELATRTFYDTFGSYYDDKDFDQFFKDN
                     YTVEKFTQEINHVDSFHYFYQEDGANVGYIKMNINSAQTEEMGETYLEVQRIYFLKDF
                     QGGGRGSQLIELAEKIAQEHNKHKIWLGVWEHNPRAQAFYKRHGFKVVGEHHFQTGDV
                     TDTDLIMEKEL"
     gene            40614..41618
                     /locus_tag="RPH49_000639"
     CDS             40614..41618
                     /locus_tag="RPH49_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDY5123828.1"
                     /translation="MIETFKAFVIDKDESGKVTPTFKQLSPTDLPKGDVLIKVHYSGI
                     NYKDALATQDHNAVVKSYPMIPGIDLAGTIVESEAPGFEKGEQVIVTSYDLGVSHYGG
                     FSEYARVKSEWIIKLPDTLTLEESMIYGTAGYTAGLAIERLEKVGMNIEDGPVLVRGA
                     SGGVGTLAVLMLNELGYKVIASTGKQDVSDQLLELGAKEVIDRLPVEDDHKKPLASST
                     WQACVDPVGGEGINYVTKRLNHSGSIAVIGMTAGNTYTNSVFPHILRGVNILGIDSVF
                     TAMKLRQRVWRRLAKDLMPENLHEIKQVITFDELPEQLNKVIKHENKGRIVIDFGVDK
                     "
     gene            complement(41800..41976)
                     /locus_tag="RPH49_000640"
     CDS             complement(41800..41976)
                     /locus_tag="RPH49_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123829.1"
                     /translation="MKIDTLRQAIIYYFVALVLSALMIYLFLTNIERVILYSCAFTVV
                     YWAIYAFDVYRKRN"
     gene            complement(42141..42542)
                     /locus_tag="RPH49_000641"
     CDS             complement(42141..42542)
                     /locus_tag="RPH49_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5123830.1"
                     /translation="MVKVTYDIPTCEDYCALRINAGMSPKTREAAEKGLPNALFTVTL
                     YDEDRLIGMGRVIGDGGTVFQIVDIAVLKSYQGQGYGSQIMEHIMKYIKNVSVESAYV
                     SLIADYPADKLYTKFGFMPTEPDSGGMYIKF"
     gene            complement(42578..43612)
                     /locus_tag="RPH49_000642"
     CDS             complement(42578..43612)
                     /locus_tag="RPH49_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5123831.1"
                     /translation="MKDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYP
                     EKIIWDIGGIAPKPCHEILKDTIKQGLYFKPEVHLNERVVDIRKKAERHFEVETEAGE
                     IYTSKAVIIAIGAGIINPKQLDVKGVERYQLTNLHYVVQSYRRFKDKDVLISGGGNTA
                     LDWAHDIAKIAKSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHI
                     SEVVLEHVESGDTHTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGFGNTTTS
                     IPGIYACGDIVYHDAKSHLIASAFSDGANAANLAKTYIQPDANAEGYVSSHHEVFKEA
                     NKTIVNKHLY"
     gene            complement(43623..43739)
                     /locus_tag="RPH49_000643"
     CDS             complement(43623..43739)
                     /locus_tag="RPH49_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123832.1"
                     /translation="MANYAIYFNNININSIMSLNDNNYQFERVNERNEYRES"
     gene            complement(43844..44275)
                     /locus_tag="RPH49_000644"
     CDS             complement(43844..44275)
                     /locus_tag="RPH49_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2871 domain-containing protein"
                     /protein_id="HDY5123833.1"
                     /translation="MRRLLYSFLFYMIIGLFSGFFYRELTKAYDFTGTTQLSLVHTHT
                     LILGMFMFLILLPLEKLFKLSSYYLFNWFFYVYNIGVIVTIGMMVTKGFFQVTGKSYS
                     PEAFAGFAGIGHTGMLAGLLLLFFLLRQAILKEPRDESFKK"
     gene            complement(44481..45758)
                     /locus_tag="RPH49_000645"
     CDS             complement(44481..45758)
                     /locus_tag="RPH49_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDY5123834.1"
                     /translation="MNIFQNKLLWIAPIATMIILVIFSLAFYPAYNPKPKDLPIGILN
                     EDKGTTIQDKNVNIGKKLEDKLLDSDSNKIKWVKVDSEKDLEKDLKDQKIFGVAIIDK
                     DFSKDAMSKTQKVVMDSKKEEMQQKVASGEIPPQVVQQMKQKMGNQQVEVKQAKFKTI
                     VSEGSSLQGSQIASAVLTGMGDNINAQITKQSLETLTSQNVKVNAADINGLTNPVKVD
                     NEKLNKVKDHQAGGNAPFLMFMPIWIGSIVTSILLFFAFRTSNNIVVQHRIIASIGQM
                     IFAVVAAFAGSFVYIYFMQGVQGFDFDHPNRIAIFVALAILGFVGLILGVMVWLGMKS
                     IPIFFILMFFSMQLVTLPKQMLPESYQKYVYDWNPFTHYATSVRELLYLNHQIELNST
                     MWMFIGFMIFGAVSSLVSAIVRKHSTKRTEVPS"
     gene            45919..46542
                     /locus_tag="RPH49_000646"
     CDS             45919..46542
                     /locus_tag="RPH49_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5123835.1"
                     /translation="MKEDRRIRKTKSSIKQAFTKLLQEKDLEKITIRDITTRADINRG
                     TFYLHYEDKYMLLADMEDEYISELTTYTQFDLLRGSSIEDIANTFVNDILKNIFQHIH
                     DNLEFYHTILQLERTSQLELKINEHIKNNMQRYISINHSIGGIPEMYFYSYVSGATIS
                     IIKYWVMDKQPISVDELAKHVHNIVFNGPLRIMAENRLHKSNLDSLT"
     gene            46588..47532
                     /locus_tag="RPH49_000647"
     CDS             46588..47532
                     /locus_tag="RPH49_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDY5123836.1"
                     /translation="MITSFRHSEDIDKHIIKTPLDHTASWINVVEPDREEIENLMEQY
                     NIPEDFIRDPLDSEESSRIEYDEDTGYSLIIIDLPIVNSTNRSVLSFVTIPLGIIIGN
                     GIIVTVCDAENEFLENLPKRDINLKFHSRFALEILTTIADHYNRNLRLLNKSRIRIEK
                     ELKNNITNKQLFKLMEVEKSLVYFLAALKGNDTIIKKLFRLPAIKRFEEDEELLEDLI
                     IENNQAIETTELHQRILESITTSYASLLSNDMNTIMKTLTLFTVLLTLPTLVFSFFGM
                     NVPLPIDDHSYISWIIVVGISLILVVIVSIFLWRKQKL"
     gene            complement(47618..49060)
                     /locus_tag="RPH49_000648"
     CDS             complement(47618..49060)
                     /locus_tag="RPH49_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sucrose transporter subunit IIBC"
                     /protein_id="HDY5123837.1"
                     /translation="MNYKQSAEDILNAIGGEENLDAMAHCATRLRLVLNDESLVNEEA
                     LNNMDVVKGTFSTGGQYQIIIGSGTVNKVFSELEKLTGKEASTTSEVKAQSAKNMNPL
                     QRFVKMLSDIFVPIIPAIVAGGLLMGLNNILTAKDLFFSGKSLIDVYSQFAGLAEMIN
                     VFANAPFTLLPILIGFSAAKRFGGNPFLGAALGMILVHPSLMSAYDFPKAVEAGKAIP
                     YWDVFGLHINQVGYQGQVLPMLVAAYILASIEKGLRKVIPTVLDNLLTPLLSIFITAF
                     LTFSFVGPITRQLGYWLSDGLTWLYEFGGAIGGLIFGLLYAPIVITGMHHSFIAVETT
                     LIADATKTGGSFIFPIATMSNVAQGGAAIAAFFIIKQNKKLKGVASAAGISALLGITE
                     PAMFGVNLKLRYPFIGAIVGSGIGSAYIAFFKVKAIALGTAGLPGFISINPVHAGWLH
                     YFVGMTISFIVAITVTLILSKRKANKEVVE"
     gene            49243..49626
                     /locus_tag="RPH49_000649"
     CDS             49243..49626
                     /locus_tag="RPH49_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDY5123838.1"
                     /translation="MKERGHIEQLWREEKYHVLLHSQQSYQMIRNALKTDLSLHQVQQ
                     MIDDALLIEPSIGSVCNAFDHMWGYFKKCANEEERQQSKLLKADFINGKIDTQTLLDF
                     LAELANKYDVQYLLQSRVLNTKRKR"
     gene            51114..53219
                     /gene="rsp"
                     /locus_tag="RPH49_000650"
     CDS             51114..53219
                     /gene="rsp"
                     /locus_tag="RPH49_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator Rsp"
                     /protein_id="HDY5123839.1"
                     /translation="MTCQLKIHHTLSTIPSRNINNIMVLFSLTSKLNITINGETKDVS
                     NYIILINHGDIYNINHGENIIELMIPVFYFHQQDDDFFNGYLDRHLLQSSNYIKSLIA
                     DLISTPTSSSLMGKNIGQSIIDTLLKEAFIRIDHEYLPNIALSNPVFIDCVNYIHDNI
                     DAHLSLKDIAMHCNISESYCSNLFVRYLSMNFKDYFTSIKLVNAINLLLSTKHSITTV
                     SELAGFNSHTNFANQFKNYLHFSPKQFRSLVSKITEPPQIHFQQDNVSQFTELISTID
                     LTAQLATNTTDIHIDDFNPKDRSQRAKVFVRFSNFNELFQFIFNEYYDINFEHLPKPV
                     VFIDDIHDIEISQTNYNLLNRCFEKLFEKNIGLAIAIKSTQQFETMKQLILTFLQGNQ
                     DYKTSKKLVKFMLVFCSNSMTAEEIHLCHLKIKNKNKEIKYSVTVDGFLETYSTVEQV
                     YDVMQRLKFHYYFIDIENSKTATHLITKNQHYHQTDTHFEQYKKFILDSGISSTQFVY
                     NNLSVSGFKYTNDGKNPIQLSDIVYHLIALLRYGGGISYQLLDDHSNYISLYNKYGSP
                     LPLMHLYKMFRPFVNEDIEITNNYVLSRKDNNYHFLLFNKINDRYMSDVKQDFIFHNE
                     LPQDSLMIIKTLNHEHGSIQHLLPISDQLVYIEKEILDELDKTNYPKTELAVQEETGR
                     TFELKLNHDEVKYICFKPS"
     gene            53290..53712
                     /locus_tag="RPH49_000651"
     CDS             53290..53712
                     /locus_tag="RPH49_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase family
                     protein"
                     /protein_id="HDY5123840.1"
                     /translation="MSNSQAIQAIENVLATSKVGVLSTAYNNKPNSRYMVFYNDGLTL
                     YTKTNIHSAKVKEIKDNPAAYVLLGYNDTTNRSFVEMEATIEIVTEQEVIDWLWETQD
                     KSFFSSKEDPELCVLRVVPQSIKLMNDKSLDTPIKIDL"
BASE COUNT        18014 a         9444 c         7596 g        18705 t
ORIGIN      
        1 gagcctctta tgcagttgct cagtcaactg tatacctttt gactttaact taagttatta
       61 gagcctctta tgcagttgcg cagtcaactg tatacctttt gcctttaact taagttatta
      121 gtgcctctta tgcagttgct cagtcaactg tatacctttt gcctttaact taagttatta
      181 gtgcctctta tgcagttgcg tagtcaactg tatacctttt gcctttaact taagttatta
      241 gtgcctctta tgcagttgcg tagtcaactg tatacctttt gactttaact taagttatta
      301 gagcctctta tgcagttgcg tagtcaactg taaaacaact tcacaaccaa ttttatgatt
      361 tccatgtata aatcattaca ttcagaccaa cgaacataaa taagcagtaa gatgactaca
      421 acttaagagt cttcttactg caattatttt tcaaatatat caacgttaat ataacttcta
      481 ttacgaaata ctcacattct gccctgcaat gcaaatttcg tcacatataa atatttttaa
      541 ttattttaaa aaatgatgca ctaaattagc aacgagcttc gcagttctat tgtcagcgtc
      601 atatgttgga ttcatctcag caatactaac tgaagacacc ttatcacttg gaataatacg
      661 ttttgccaat tcaagaacag tatgtggata caaacctaac actgccggcg cacttacccc
      721 aggtgcaaac gcactatcaa tgacatccat acaaatcgta aacataatga catcatgttc
      781 atgtacaaaa cgttcaatca tatctttaat tgttggtgat acgtgactca ataattcatc
      841 tgcaaagaca taatcaatct ttttctcttt agcataatca aataaacttt gcgtattacc
      901 accttgagca ataccaagca ctaaataatc tgtgttttca tcttcttcca aaatttgtct
      961 aaagctcgtt ccagatgtag attgttgttc agcacgtgta tcaaaatgcg catcaatatt
     1021 tatcacacca atagattgtg ttggatagac tttacgtgtt gctaaatatt gagcatacgc
     1081 aatatcatgt ccaccaccta ataaaaatgt ttgtctatga ttagcaattg acttcgctgc
     1141 aagcatagca aattcttttt gagtatcaat taattcctca tgatcatgat aaacatttcc
     1201 gtaatcgact aaagtttcac attgattcaa atccggcaaa cctgcaaatg cttgtttaat
     1261 cgcatctggt ccttcttttg caccaatgcg ccccttgttt aaagcaacac ctttgtcaac
     1321 agcatagcct aatataccga cccctgatgg catactactc ttttccagct tagacaaatc
     1381 ttcaaatgtt actgtttgaa aatgtctaaa ttttttcggg tctgtttcac tatctaacct
     1441 tccagtccat aaatttggtt caccttgctt gtacacagca tttccccctc ttatttatgt
     1501 ggcttattaa caattaaagt ataacgtata ggaaattttg aattcaattc atagttaaat
     1561 ccgtatctta aaaatactta tctacattac ttttacccct attttctatg taataacgaa
     1621 tacttagctg atttatgtta ataaaatacg tcaagactat tacattttca ttaatattga
     1681 catagacaat ttatctctcg gcttgtaata tgtataattg ttactaaaag atattttgct
     1741 tgttacctaa tggaggttac atataatgaa gaacaataaa atttctggtt ttcaatgggc
     1801 aatgacgatt ttcgtcttct ttgtcattac aatggcgtta tccattatgc tcagagattt
     1861 ccagtctata attggtgtca aacactttat atttgaagtt acagatctag caccattaat
     1921 tgctgcaatc atttgtatac tcgttttcaa atataaaaag gtccaacttg caggtttaaa
     1981 attctcaatc agcctgaaag taattgaacg tctattgcta gctttaattt tacctttagt
     2041 tattctaatt attggtatgt acagctttaa tacatttgca gatagcttta ttttattaca
     2101 atcaacaggc ttatcagtac ctattacaca cattctgatt ggacatattc taatggcgtt
     2161 cgtagtagaa ttcggattcc gttcatactt acaaaatatt gttgaaacga aaatgaacac
     2221 gttctttgca agtattgttg ttggtttgat gtattcagtt ttctcagcaa atacaactta
     2281 tggtacagaa tttgctgctt ataacttcct ttatacattc tcattctcta tgatccttgg
     2341 tgaattaatt agagcgacta aaggacgtac aatttatatt gcaacgacat ttcatgcttc
     2401 aatgacattc ggacttattt tcttgtttag cgaagaaatc ggcgatctat tttcaatcaa
     2461 agtcatcgcc atttcaacag caatcgttgc agtaggatac attggtttaa gcttaattat
     2521 ccgaggtatt gcatatttaa caacaagacg aaaccttgaa gaacttgagc ctaataatta
     2581 tttagaccat gtcaatgacg ataaagaaac taatcatact gaggctgaaa aatcttcttc
     2641 aaatattaaa aatgctgaaa aaacaggtgt agctactgca tcaacggtcg gtattgctaa
     2701 aaatgatact gaaaatacag tggctgacga accaagcatt catgaaggta ctgaaaaaac
     2761 agaagctcaa catcacatag ataatcaaac tgaatctaat catgatgaag atcatgacat
     2821 cacttcggag tcagtagaat cagcagaacc agttaaacat gcaccacaaa gtgacgattt
     2881 aacaaacgat tcaaatgaag atgaaaaaca atcattaaaa gaacctgcga cttataaaga
     2941 agacagacgt tcatcagttg taatcgatgc agaaaaacat atcgaaaaaa ctgaagaaca
     3001 atcttcagat aaaaacaaat aataacaaag cgcttgctag tacctcttaa aaagatgatg
     3061 ctagcaagcg cttttctata ctatatatta tttttctaaa attttaacac cctcttgagt
     3121 gcctacaata acttgatctg ccatatctaa gaagtatcct gtctcaaaca cacctgtcag
     3181 atgaattaaa tactcatgga acttatatgg gtcaattcct tttggtaact tacaatctaa
     3241 aatataattg ccattatcag ttataaatgc gacatcttcg tttacacggc gttctacttt
     3301 tatatcagcg tatgattcaa ttttacgtaa tatgtgatac cagttaaatt tatccacctc
     3361 tactggtaac ttaaacatct cacctaagta ttgaaccatt ttcgtttcat caacaaccac
     3421 aacaaaacgc gatgccattt catctataac tttctctctg aacagcgcac caccgccacc
     3481 tttaattata tttaaagatg gatctacttc atcagcacca tcaattgcta agtcgatatg
     3541 atcaacatca ttgatttcac atattttaat acctaattct tttgctaaaa atgcaatttt
     3601 attagaagtg catacacctg taatattgta accacgttct ttaattagtt gcgccatttg
     3661 aggtaagagt aattccattg tacttcctgt accaattccc agcgtcatgt caccattgat
     3721 ttgacttaaa acatcattta atgtcattaa cttgagtgct ttgacatctt tcatgaaggt
     3781 agcctcccat atttatgtaa tctattcaat tcatatttta catgactctt ataaattaac
     3841 atacccttat ttctaacatt tttttaaaca tatcaatcag aatttacaat tctaaaaatg
     3901 ttttatagta caatatattt taaataatac tcgttaagga gaatgatatg atatcaattc
     3961 acgcgatttc gacaggaaaa atccaagatt tgccttatag ctcgaaaaga ccgatgcgct
     4021 ctgctttaga taaaactaag atttcgcaaa caacatggtt atcttcaact ggtttcactg
     4081 gtgatgaaca ggcttataaa gatcatggtg ggccacataa agcagtttgt gggtttagta
     4141 aacacaacta tgcactgtat caagatgatt taccctcact acctactcat gcgatgtttg
     4201 gagagaattt aacatttgat tatttagacg aatctgatgt ttactttggt aatcaatatc
     4261 gtttaggtta tgcgttaatt gaggtttctg aaattagaga accatgctgg aaaattcaag
     4321 caaaatataa tattcctgat ttagtgaagc gcatgtctac atctggtaaa acaggtttct
     4381 atttccgggt attaaaacaa ggctatgtat ctccaaatga tcagctttac ttaatacaag
     4441 aagcaccaat cgaacatcgt ttatctgtac aacagcttaa tgacctttat tataatgata
     4501 gacaaaatca agatctgtta cgatatgcac taaacaatcc atttctgtca ccaacaagac
     4561 gcgataaact tcaaaaaatg tataacagaa cattgaaata attacctttc attataagtg
     4621 ttaaatgaac ttttcaaaac aaaaggaatc aacttacaca tcgtttgtat aatagtctta
     4681 tctataacta ctgatgctat tgattccttt tttatgttat atattttttt atttcaaact
     4741 gtatattaat gatgtcactt catttgattc gattcttgat aacctattca aaattccgcc
     4801 aaacaacata tatattatat aaatgccgat acttttaatc attttctact ttttcttcga
     4861 tacggaaact tgttttcgaa ttgaacactt caccagcttt taaaattgac ggtgctttgt
     4921 caccatataa attaatatca tttggtaaaa attgtgtttc taatgtaaag ccagaatgtg
     4981 gtttataaat attaaatgga ctatcccact catcaggctg attaaaagta aagaatacaa
     5041 catgaggcat atctgtatcg acctctaaca taaattcatg attttcaaca tacattttat
     5101 gttcaccaac tgtaaatggg tgatcgagac caccaaaacg tatcatttgt tggcttaatt
     5161 gcgcatgttg tgatgtaaaa atatcactca attttatctt gttatcttca aacacttcat
     5221 gtaaatctag aatatcacct gtaacaatat ttcgctcatc taatacatac atatctaatt
     5281 gattacttga aatgcgatga ttatcaacga cattattatc tcgattcaaa ttgaagtaca
     5341 catgattcgt aggactaaac aatgtgtctt ctgatgcaac tgcttcgtat tcaatcgacc
     5401 attggtgatc cgcatcataa atatgtgtaa tcgtcacatc gatatcaccc gggaaatgat
     5461 catcagctga tttcaacacc gtcttaaata tcactttaat ttgagcaatt tcatttctaa
     5521 tttcataatc aaataactta ttgtccaaac catgacatcc accatgtaaa tgatgttcgc
     5581 cgttgttttt ttctaactga tattctttac ctttcaactt aaatttagca ttatcaattc
     5641 taccgctata tcttcctata gaagcaccaa atttaaaagg attactatga taaaattcat
     5701 ccgcttcaac aacatttcca agaacaatat tattatcatg atatttccaa gacactactc
     5761 ttgctccata attcgtaaaa ataattttag tttcatcatt atcaattttg attaaatcta
     5821 caccttgtct ttggtgctca acttcaacta tcatttttac ttctcccttc taaccacaag
     5881 tgttcaagct ctgctgggta gcaacattac taaaacacct acaatacaaa tgattgcacc
     5941 gataacatca tatttatctg gcatttgttt atctacgacc atcgcaaaaa tcaaactcat
     6001 gatgataaat acgccaccat atgctgcata tactcttccg aatgatggaa atgattgaaa
     6061 tgtcgcaatg acaccatata acatgagtat cgcaccgcct attagcccaa caagtgaaga
     6121 ctgtccttcc ctaagccaca gccaaatcag gtatccccca cctatttcac ataagccagc
     6181 taatataaat ataaaaatcg gatataacat gaaatcactc catcacacat ttgctaccaa
     6241 taatctatcg gctacatatc atttgtttac atttcttctt acttcacatt cccattttaa
     6301 aaagttcgtt ttcacattca tattgtacac ttttttagac attattctat agctaaatat
     6361 aaaaaaataa gagtaacacg ctttcatcat cattttatat gataaatgtg tgtcactctc
     6421 atcaatttta ttttttaaat acacgtttca ttgaattaaa taagccacgt tcaaatgtaa
     6481 gtactgaatc tttatatgtt ttaattgcaa tccatatcaa gacagctacc attacaattg
     6541 agattaatga acttaagatg acctcatgta tttgaagccc tgaagtttga gcgcgtacaa
     6601 ctaattgaaa tggcgctaaa aacggaatat aacttgtgat taaagcaagt tgcccatcag
     6661 gattatttat cgtgaatatc gcgatataaa atgcaatcat accaagtaat gtcagtggca
     6721 tcaaagattg atttaaatct tctattctag atgttaatga tccgagaatg gctgcaagta
     6781 atacatacgc cataattcca acaatactac taataattcc gacaataata atttgccaag
     6841 acaattgatt catttccacg ttaaaacctt gtagcaagtc ttttaagtca aaggcaaaaa
     6901 tgcatataac tgccatcaat acaattaaaa taatctgagt cacggcaact gctataacgc
     6961 ctaaaatttt agcaaaaata tgttggattg gtgaaatact tgtaataatc atttcaatga
     7021 cacgcgatgt tttctcacta gcaatttcca tagctatttg agatgcataa tttaaaacaa
     7081 taaagaacat tagaaagata atgccgtaag ctaaagcata gttgaaaatc ttttgtcctt
     7141 ctgatacttt atcgacttca tcattagaaa tcaccttatt atcaacttta ctttgtgctt
     7201 gtaatttttg taagtcttct ttgttgatat ttaattctcc ggctaccata tttgtttgaa
     7261 tagctgtaag cagtgcttgt actttttgtg aatcttcatg acttactcgc ttctcactaa
     7321 tgattgtccc ttgtaacgtg cgattttgat tcaccttgat aatataagct ttatcaagtt
     7381 tatgtttttt tacttctttt tcagcatctt ctatagaaac tttagtaaac ttagcatcac
     7441 tatgaaatgt attcgcctgt tgcttgaaaa ccttatagat ttgttcattc ggtgctgcta
     7501 caccaatttt atctggacca tcatcaaaca tgttaataat cttatcaatg ttagataggc
     7561 caatcattaa ggcagcaata ataatcataa aaattacaaa tgatttagct ttaatttttt
     7621 tgatatatgt caaagtaaat gtcgcccaaa acttatgcat ccttgccacc aaccttctca
     7681 atgaatatat cttgtaatga tggttctaca acttggaatc gtttaacata accttgatgt
     7741 gccacaactt gataaatatc tttggctacg tcttcattct caatcgtcaa ctgaagacct
     7801 tgcttcatgt tttcactatg aatgatgcct ctaatgtttg ttaaatctgg tagtgttgtt
     7861 tctgattcaa tgacaacttt cttgttacca ttagatgcac gtacatgatt gatatcacca
     7921 gaaacaacaa gttgaccttt atctaaaata caaacatcat cacataattc ttcaacatgc
     7981 tccatacggt gagaactata aacgattgta ctgccccaat catttaagtc tttaacagct
     8041 tcttttaata actcaacatt aactgggtct agaccactga aaggctcatc taatattagt
     8101 aattctggtt tatgtaacat acttgctaac agctgaattt tttgttgatt cccttttgat
     8161 agactatcaa ttcgtttttt gcggttttca gtaatatcaa aacgctcaag ccaatacgat
     8221 atttgctgtt gtatttctgt ttttgacatt ccctttaaag ttgccaaata tttcaattct
     8281 tcttcaactg tcaatttccc atgtaaaccg cgttcttccg gtaaataacc aatacgattg
     8341 tacattgttt tatctagttt tttaccgtta tacgtaatgt gtccttcagt tggttcactt
     8401 aagcctaaaa tcatacgaaa tgtcgttgtt ttacctgcac catttcttcc tagaaaacct
     8461 aacattttgc ctgattctaa ctctaatgaa atatcattta ctgccgtcat cttgccaaaa
     8521 cgtttcgtaa catgttcaat tacaagtccc atacttcgcc tcctaaaaca atatgtattt
     8581 atcttaatat aacatttcta ttctctataa atgcaatatt tttaaagtga atttattttt
     8641 aaaatttctg aaatcgaaaa atttaaatag taccatcttt gcatgttaag tatgattagt
     8701 gttggatatg cttttttcca tgcctttatt gccttattgg taaaaaaata tcccagcatc
     8761 attgtgccga gatatttata tcattacaat tgattatctg tttctcccgg tgttttcggt
     8821 gtttcagatg tcactggttg atttttaatt gaagatgggt attttgggct ttcgccatat
     8881 ttatttgccg gcttactatc aaagcatagg aatactatca taacaattgt taggcttaaa
     8941 taaacaaaat aaagaaatac taacaaaata ttaagaccca tcggcattaa ggtaaaatca
     9001 ctgtcataat aactatcgat aatctgtaat actatataaa atataatact gaatgctgtc
     9061 ataatcattg gaaataacat tgttcttgat atatcgtgaa atcttcgaac gcacaacgct
     9121 aaatttggaa taaacgttgc caaactatag acaaaagtat acacagatgt aaggataatc
     9181 atcaatatac tcataactat taatgtttcg ttatctgccg ctatagaaat aaagaataga
     9241 aataggctta ttattagcac acacacagct ggaaccataa atattaaatg ccacaacatc
     9301 atataccaat attcactacg tcttgatctc cccttaaaat taacataatt tttccaaaat
     9361 aatacgaatg atttcataaa acctacttga ggtaattgtt ccattgtaat ctccctttcg
     9421 ttaatcatat ttatattttt aattattatt accgttataa tttacaagat tcattatcaa
     9481 gccacttcat ttcaatcgtc attcactttg gaaaatgaac tttatatttc atcactagtt
     9541 aaatgaaaac ccgctacaag tacgcatcta tatggagact catttgaaag tcaacgcttc
     9601 gttaactata ctaaaaatat gtcacactgc aatgttcgcg ttcaaaagag actcaatctc
     9661 tgcaaataaa atattccata acaaagtata tactttacat ttttataatt cttaacaata
     9721 ctattttatc aaacatttac cacaataaaa atatcttttt catttttatt taaattaatc
     9781 atataattgc aaggagaata ttatggattt cgttaataat gatacaagac aaattgctaa
     9841 aaacttatta ggtgtcaaag tgatttatca ggataccact caaacgtata caggctacat
     9901 cgtggaaacg gaagcatact taggtttgaa tgatcgtgcg gctcatggct atggcggtaa
     9961 aataacacct aaagttacgt cattatataa acgtggtggt acaatttatg cacatgtcat
    10021 gcatacgcat ttactcatta attttgtaac aagatctgaa ggtatacctg aaggcgtact
    10081 tatccgcgca attgaaccag aagaaggttt atccgctatg ttccgtaaca gaggtaagaa
    10141 aggctacgag gtaacgaatg gcccaggaaa atggactaag gcatttaaca ttccacgggc
    10201 tatcgatggc gctacgttaa atgactgtag attgtctatt gatactaaga atcgtaaata
    10261 tcctaaagat attattgcta gtccacgaat cggtattcca aataaaggtg attggacaca
    10321 taaatcttta cgttacacag tgaaaggtaa tccatttgtg tctcgcatgc gtaaatcaga
    10381 ttgtatgttt cccgaagata cttggaaata aatgccatct ttcattgatt actatcatga
    10441 aaatgaaatc tatctcctta taagtcaatc aatcgtaccg tcaacatgcg gatgggttga
    10501 ttgtttttct ttttgtccat catatttttt gattcatctc ctctttttga acttgttctt
    10561 aattataaaa tataacaata gaattattta taattattaa atttagatgc attaatatta
    10621 ttgatattat tttcataaac tagaaatatt gatttgttgc atgtataatg ttaaaagtgc
    10681 ccttttataa cgcttacata taaaagctta tttagggaga gggatattca acaaggggga
    10741 tttgaaaatg atagaactta atgcaattac aacattatgt ttagcctgta tactttactt
    10801 acttggtaaa gctatcgtta atcacgttaa ttttttaaaa cgcatttgta taccagcacc
    10861 tgtgattggc ggcttaatct ttgctatttt agttgcgact ttggattcat ttggcatggt
    10921 taagattaaa ttagatgctt cattcattca agatttcttc atgttagcat tctttacgac
    10981 aatcggtctt ggtgcatcat tgaaattatt taaattaggt ggcaaagtct tgctattata
    11041 ctttatgttt tgtgctatca tttcagtcat tcaaaacata gttggtgtat cactagcaaa
    11101 agtattaaat attaaacctt tgttaggatt aacagcaggt tccatgtcta tggaaggcgg
    11161 tcatggtaat gctgctgctt atggtaagac aattcaagat ttaggcattg actcagcact
    11221 gacagcggct cttgcagctg caactttagg tcttgtattt ggagggctta tcggtggtcc
    11281 tgttgtaaaa tttttaatca aacgttataa cttaaagcct caacatagtg acgatacatt
    11341 taaagattat agccaagtag catataacga acatttacat agtaaattta atgccactga
    11401 agtattcttc attcaattta caatcgttgt attctgtatg gcagttggaa gttatttcag
    11461 tcatttgttt acatctcaaa cagggattaa tgttccaatt tacgttggct cattatttgt
    11521 agctgttatt gtccgaaata tctctgaaag ttttaatttt aatattgtag atttaaaaat
    11581 tactaatcaa attggtgatg tcgcattagg tattttctta tctcttgcgc taatgagcat
    11641 tcaattaatc gaaatttata aacttgctat acctcttatt attatcgttt tagttcaagt
    11701 tgtcgttatg attttatttg ctgttttaat tttatttaga ggtttaggaa aagattatga
    11761 tgctgcagta atggtaggtg gttttatcgg gcatgggctt ggtgcaacgc caaatgccat
    11821 ggcaaattta gatgttatta ctaaaaaata tggaaactca cctaaagcat atttagttgt
    11881 acctattgtt ggtgcattct taatcgattt aattggtgtt atagtcatta tgggattcat
    11941 tcaatggttt agttaaacac caaactcata aataaaagag gaggccttcg cctcctcttt
    12001 tatttatcct cgatgtatat tcaagttacg ttgttctatc catgacaata tttccggact
    12061 aaatacgatt tgtttttgtg ttaagtcgtc aatattttta gcatctaaca tcgtcattat
    12121 tgatttcatg tgttcaataa atgattctac ataagctact gtatgtgcaa tgccattatt
    12181 ttcaacttga tttaaaaacg gacgtgacat accagttgcc tttgcaccaa gtgctaaact
    12241 tttaattgca tcgagtggtg tacgtaaacc accactcgcg aaaactgaaa tttcgctttg
    12301 ataagccgtt gtttcaagta atgactcaac tgtagactgt ccccatgatg ataagtaatc
    12361 catatcttta tttgcacgac gttcattttc aatatctaca aagttagtac cacctttgcc
    12421 actaacatcg acatacttga cgcctatttg ttgtaagtca tgcattaatt ctttgctcat
    12481 accaaatcca acttctttta taatgactgg aacagacact cgtgatacaa tcgacgctat
    12541 attatctaac caagtcacaa attcacgatt cccttcaggc ataactaatt cttgaggaga
    12601 attaacatgg atttgtaacg cttgtgcctc aagtaattca actgcttcca aagccttttc
    12661 tactggtacg tccgcaccaa cattgctaaa aatcatgcct tcaggattca tttttcgcgc
    12721 aatcgtaaac gtctcagcca tgcgtggatt tctcaatgct gcatgtgttg atccaactgc
    12781 catcgctaag ccagtttctc ttgcaactac agctagcttt tcattgatgt ttttcgtcca
    12841 ctcgctacca cccgtcattg cattaatata aaccggatat gccatcgtta agtcaggcgt
    12901 ctgtgatgtc aaatcgatat catttacatt aattgatggg atagaatgat gcacaaaacg
    12961 catcttatca aaatctgaat gcattgcgtc agattgagcc attgctattt caacatgttc
    13021 attttttctc tgttctcttt gaaaatcact catgattaaa cctacctttt cgtcatttct
    13081 aatttaaaac cattttttac gtctgaaaaa gatgattaat acgacagcta taacaaacat
    13141 tacagctaag caaatataat atccataatg taaatgtaat gccggcatat ttacaaagtt
    13201 cataccataa atcccagcta tgaatgttaa cggtgaaaat ataactgata ctaatgtcag
    13261 tacttgcata atactattca ttctaaatga cgtgtatgac tcaaaatttt ctcgtatttc
    13321 gtttgtcatt tcttgagcag tgcgaatgat attacgttgc ttaatcaagt ggtcatcgat
    13381 atgttgaatg tatagcgaat gtttattatc tataatcaaa tcaccatttt gtttcattgt
    13441 atcaattagc tcttgcatag gaaacagtac acgttttact ttaatcaaat ccgaacgtaa
    13501 cttaaagaca ctatccatga ccattttatt aaagcgatca tctacatggc ggtcttcaaa
    13561 atgataaaca ctatcttcaa gtgcatatac aaagttgaaa tatttatcaa ccatcatatc
    13621 taaaattaat atgacgacat ctgcacaatc taattctgca tctaatgtat tcatatactt
    13681 atagactact ttatttaatg attccaacgt ttgatgatga tatgttacta atacattgtc
    13741 ttgtataaaa atatttagtg ctattggtga atagtttgac cccataatac tatgaaatac
    13801 taagtattga taatctttat aagatttata tttagctcgt ggcataccgt taattgcatc
    13861 atccacttct aaatcattaa aattaaaatg tgctttaaac cattcatttt cttgttcatt
    13921 cggttcatca aaatcatacc aaacaatagt cgcatctttt ggtatctctt tgatatcatc
    13981 aactacttta aacggttcat atgtagtttg ataccgtatc gttaaagcca tcgatactcc
    14041 ccctaaataa cgaattctct attattttat catgaattaa ataacgtgta tgtcttaatt
    14101 tattttagta tgatagtcac taaggagatg gttattatca aacaactttt tacacatact
    14161 caaaccgtaa catctgaatt cattgaccat aacaatcata tgcatgatgc aaattataat
    14221 atcattttta gtgacgtcgt gaatcgtttt aattacagcc acggtctttc tttaaaagaa
    14281 cgcgaaaatt tagcatatac gctatttaca ctagaagaac atacgacata cctctcagaa
    14341 ttgtctcttg gcgatgtatt tactgttact ttatatattt atgattacga ttataagcgg
    14401 ctgcatttat ttttaacatt aactaaagaa gatggtacac tagcatcaac aaatgaagtt
    14461 atgatgatgg gaattaatca gcacacacgt cgttctgatg cttttcctga atcattttca
    14521 acacaaatag cacactatta taaaaatcaa ccaactatca cttggcctga acaattaggg
    14581 cataaaatag caattccaca caaaggagca ttaaaatgac agatgcatta caacaaaaga
    14641 ttcatatcga attactagat ttattagatg atgttaagtt tgaattaaca gaattaaatg
    14701 cacaaaaagg gttatacatt aacggaccag caaatcagct acttaagcgt ggcgtgcata
    14761 tggcttatgt tcaaggacaa aagcaagcca tcgataatat tatgactatt gtggaacagc
    14821 agcttgaaga tcaacatttc ctagaacatt atgataaatt tcaaaatgag gttgctcatc
    14881 gcaattatga taaaacagct aactttgcag aacttagtga tattccacgt caattcgata
    14941 attttttaga tcaattttat caaattaaag ggcaatactt tatcatcaca catatcaata
    15001 cacttattgg tgattttcac tcagaagctc attaacaatt agtctatata acccttgcta
    15061 tattttcaaa aaaaaaccaa ttacgttttc atgtcaaata tcatcttgca tgaaatcgta
    15121 actggatcaa ttgtatgtta ttagttattt tgtgttacat cctcatctat cgatttggca
    15181 atttgtttaa tagctttatg tgattgtcta attggataaa ttggaaaatc atgtaccatc
    15241 ttaggataat cataaaactc aatgtattga tgatgttgca acatcatttg ttcaaatagc
    15301 ttcatatcag gatgtgtcat ttcacgtcca ccaccaaaca tataaactgg tggcaatcct
    15361 tctattgtgc cattaattgg cgatatgcgc ttatctgtta atggtaggcc attcgcccat
    15421 tttttcataa tctcattgac accaaactga cttagaaccg catcttgttc gattaaggcg
    15481 tccgaaatat ctttattaga tagtgttgca tctaaaattg gtgagattaa atacaattta
    15541 ttcggtaatg gctgttgatt atctaaaaga gattgtacaa aggataatgc cagtgcacca
    15601 cctgaaccat cacccatgac tacgacattt tgatgtccta cttcagatac taattgatca
    15661 taaacacgtt gtatcgcttg gaaagtatcg tcaatatgaa actctggtgt ctttggatag
    15721 ataggcagta caacctcata taatgtactt aaagtgattt tatccaacaa tctccaatgg
    15781 aacggtgatg gttgtagtgc attgaatcca ccgtgaatat ataaaatttt cttatcaatt
    15841 tgatgtctga aattaaagcg aaagacttgc atatcatcta atgataactt ttctaaattt
    15901 gctttaacat ttaatgttga aggctgctta tgtttttttc tattttcaat ttttctttta
    15961 taaaaaaatc tttcaacatc ttgatcattt ttaaacataa tcgagcgatt gtgaagcaaa
    16021 tatttattga caacgctatt cataacacgg tttctaatca atgtcttaac ctacctttat
    16081 atattttatg tatccaatga ttgtctatcc cctacattct tcgccaaaaa aagtatataa
    16141 tatagaagat attttctttt tcactttcaa atttaagact acaattgaac agtgattttt
    16201 catcattata acagacaact agacatattg ataagtaaag aaaagaactt tatacggagg
    16261 tgccttgcat gacaaatcca aatcaacgat tagaaccatt tgatgagaca tttcaacaac
    16321 cgaatattca tcgtggtaag cgatatggta agaaaaaacg ttcattggta agcatgatta
    16381 ttcaaatcat agttgttata ttaaccgcaa tcgctggata cagcatgtgg aaacaaccta
    16441 tttttaatat tgtcttcacc aaagaatctg tagattttga tggcattaaa aattttaacg
    16501 agacaattgg aaaaatgcat caattaaata ttaatttggg taatatcaat gatttacaac
    16561 aaggaatcga tcgcttaatt ttagtcttta acggtttctt tattttatgt atcgttagcc
    16621 tagtcataac aatactgaca attgtattta atcgcacagt tctaaaagta gtaaatattt
    16681 tagtgttaac aattatgtta gtcattacat tgtatttcag ttatattatt aaagcactcg
    16741 cacaagaaat tgcagatgtt tttaaaaaat attatgtaaa tgtaccacca gatcaagtga
    16801 taacagaagc tgacgctatt cataacggca tcattttact gggctgtagc atcggtttac
    16861 ttgttataag cttattcttc cgtaatcgca tgcctcgttt aaaataatga tatacagtag
    16921 ggattgggac agaaatgtta ttttcacaaa attcatttcg ttgacccact tcctgctttt
    16981 tctttattaa tgacctacta cgtcaatgcc aaattttaat ataattcctc taacattcta
    17041 caaatcaaca aataaaaaaa gtatcgataa ccatatattg gcaccgatac tttaaaaatc
    17101 atgtccccac aacataattt ttgattagtc acacttcaat taatttattt tatttattca
    17161 tgattgatac tattatctgc atctatcttt tgagccgtag ctttggcttt tttgttgctt
    17221 tgtaaaaata aacataaaat caaggcgatg acgctaaata tcgttgcaac tataaatgca
    17281 tcattaattc cttcaactgt tgatagttta tttacaaatt gtaataacac tttcattgcg
    17341 ccttcttgac caccatattg cgatgctaat tcacgcatat gatcttgtac aacaggattc
    17401 gttttatcta actcttcccc aaaagctgat aaatgttgtg tagtttgtgt tgtcattaca
    17461 gtaaccaaga ttgctgttcc tatagaacca gctagttgac gcatcgtatt taagaaggca
    17521 ttaccatggg aggcaagtcg tccgggcaac gcattaatag ctgctgttac cattggcatc
    17581 ataataaatg ccataccaaa tgaacgtaga acatagatgc ccatgattgt catatatggc
    17641 gtatccatat tcaatttagt taattcccac gttgcgtaag tcatgacagc aataccaaaa
    17701 atggctaaag gttttaaacc aatcgtgtct aacaacttac cagcaaatgg tcctagtaga
    17761 cccataatta gagaaccagg taataataac aatccggaat ctaatgctga gaaaccacgt
    17821 aaattttgta agtacattgg taataaaatc ataccaccat acaaactcat cattacaacc
    17881 atattaatta ctgttgttaa tgtaaatgtt ggaaatttca atacttctaa attcaacatt
    17941 ggcgctttca ttcttaattc tcttattaca aatagaataa taaagataat accaatcgca
    18001 aacattgttt ctatctcaac agaaccccag cctttgttcc ccgcttctga aaagccgtat
    18061 aacaaagcac cgaaaccaat cgtgctaaaa atgatacctg ggatatcagc tttagggttt
    18121 gtagtatatt gatataactt aaaccataca aaacctacta agattgcaat aattccgata
    18181 atgaacatac cgtaaaacat cacattccaa tggtaatttt gtacaatata acctgataat
    18241 gttggaccga ttgcaggtgc taaaatcatt gcgataccca ttgtacccat ggcagcacca
    18301 cgtttttcag gtggataaat tgtaataata acaattgaac ctaatggcat tagtacacct
    18361 gcaccaatgg cttgtaatac acgtccaacc atcatgattg ggaaattcat tgaaatcgca
    18421 catattaatg aaccaattgt aaagagtact aacgcaacta aaaataattt tcgatatgaa
    18481 tatttattaa atagatacgc cgtaattggt attaaaatac cgtttactaa catgaatccc
    18541 gtcatcaacc attgtcctgt tgacgcagaa atattaaatt ccgtattaat ttttggcaaa
    18601 gcaacattta ataatgtttg gtttaaaatc gcaataaaca taccgaataa taatgccgct
    18661 aatattttac cgcgtgaaac accttcacca aaaataaagt ttttatgttc tttttttatt
    18721 ttttcattta ctttatattc ttctgattta ggatttttag cagcatatac ttcttcatca
    18781 gattcattat tatcagtgaa tgatgcttga ttttgttcag atccctctgt ctgtttgttt
    18841 agactaactt gattctgatt atcttgattg tcaatacgtg cctcttcacg cgccgtatgt
    18901 tgtgacgatt gatcagttgt tctgtctaaa tcacttgctt taaatttaga ttgatttgat
    18961 tgacgtgtcg caaaatgttg ttccttttgt tggcgttttg cttttcttct tgatcttatt
    19021 aacaataaat tgataacccc aacaataatg agcgctaaaa caatgtagct aataatgaag
    19081 gtcgtagtca tttaatgacc cccttaattt ttatgaattt ttacttcagc gttcattcca
    19141 ggaacaactt gtttagacgg ttctgaatct aacgtaattt taacaggtat aacttgagat
    19201 actttagtat agttaccatc actatttgat gatggcatta atgaaaagct tgcagcagta
    19261 gcttttccaa tactatcaac tttaccttta acagaagctt tttgaccgtc aatagtcaca
    19321 tcaacatctt taccaacttc aacatcttta atatcttttt cgtcaatatt tgcagttaca
    19381 tataaatcat ctaaattgta agcataagca attggattgc ctgcttgtac catagaacct
    19441 tccatgccat ctaatttagc aattgtacct ttttgtggca ttttaagttc catatcttta
    19501 gtttcgccat cttgaccttg aacagtaact gttgctactt tatcaccttt atcaagtttg
    19561 tcaccttgct taacgtttag tgatttgatt tgcccagaag ctggacttgc tattttaatt
    19621 tgatcgccat ttactttagc attatcagtt gtgatataac ttgttgtttt attccagaaa
    19681 taaaaaccag caatcccaat tgctagcagt acaacaaccg taatgacatt aattaatatc
    19741 atctttttca tgaaacattt cctcctattt gcttttaaaa ttcactttat ttattataga
    19801 gacatgataa ctaaaaaaac accaacaatt tttataagag tgttggttaa atttcacaaa
    19861 ggtgtaacaa tatgaaacga caagccaaaa tagaaattca aaacgcactt gttgatttga
    19921 tggctgaata tccttttcaa gaaatatcca ctaaaatgat ttgcgcgtat tgtaatatta
    19981 atcgttctac tttttatgat tattacaaag ataaatttga tttattggat accatcaact
    20041 caaagcataa agaaaaattc caatttcttc taagtgcgct acatcataat ttcgaaaata
    20101 ttaaacaaga taagcttaaa ctttataaat tcttcattat tattgctaag tatatcaagc
    20161 gcaatgagca gtttttcaaa gacattttag ttacctatcc aatgaaaaca ttattcatag
    20221 actatataaa tttagcgaga gattactatc aacaaattat gaatgactat agtactacag
    20281 taaccaataa acagctttat gttacatata tcataggcgg tcaagctggg gtgtttatta
    20341 attggctttc gaatggttgt aatgaatcac ctgaagaagt tgctgacatt ttattggcta
    20401 atacgattaa acttcaaaac caataatacg gtttcattct aataaagaaa tgctataaaa
    20461 caactagata aagttaaacc aaatggacag ataatagtac atatgtaacg gtgctatcaa
    20521 tataaaaatg ccgagatttc cacataataa tctcggcatt tttatttttg atgctaaatt
    20581 cataggtcta tgaatagctc aagttttgtt ttttaatttt tcaattcaat ataatagaag
    20641 aaactatgtt tatcatcgat ttgttttaaa taccttcata ttataaatct gtaaaataat
    20701 taatataact gctgtagcta taataataat tatgtaaggt ataggattat cttcaccttt
    20761 tacccccact aatggcgatg caataccacc aaataaaaac tgcactaaac ctaataaact
    20821 tgatgaactc cctctaccac tactactttc atccatagct attgtaaaac caagtgtcgc
    20881 aacacctgtc actggtgcta ttaaaatgat aaatcctatc gctaaaatcc aaaagttcca
    20941 atgattaagc aatacaatcg tcactaaaat tacaccgata atctgaatca tcgtcatgac
    21001 tctcatcaat ttttgtgagt ctataaaatc aacaaggtag ccagtaagtt gacttgatat
    21061 aatgagcgta ataccaattc ctgcaaacat ccaactaaat tgtattgcag tcatgccata
    21121 aattttttga ataataaacg gagacgcaga aatataagta aataatatta caaatgtcat
    21181 accttgaatg agcattggta atacaaaacg tggcgtcttc aataatattt tgaagttttt
    21241 aaacattgtc tttaatccac tacttgattc acgatttgtc actgttaatg attcaggtac
    21301 ttttaataaa gaacctatga ccataacgaa gccaaagata gtcaaaatga caaagaccat
    21361 acgccagaca gaataattta aaattatgcc tcctattgtt ggcgcaacaa ctggtgcaat
    21421 accattaaca agcatcaata atgccataaa cttagttagt tcattaccac tatacatatc
    21481 acttgctata gctcttgaaa taactgctgc tgctccacct gtcactcctt gaagaaatct
    21541 taatgcaatc atcagccaaa tattatgtac aaaaacaata cctaaacttg ctaatgtaaa
    21601 aataatcata gctataataa gcggttttct gcgtccattt gaatctgaaa ttggaccagc
    21661 aaacaaatta ccaaacgcta aaccaatcat aaacatcgat aatgttaatt gtgcgttaga
    21721 cgtcgttgtt tgaaaatcat gtctaatatc tggtaatcca ggcaaaaaca tatctattga
    21781 taatgctcca atggcagtca aagatcctaa aataataata aatatcggtg aacgcttatt
    21841 aaaacgcttt aaatcattca ctatatttcc tcctttatat aatgattagt ttataactat
    21901 cacgaacaga aactaaattt aaatatgctc ttttacatat tagcattact cacaagtttc
    21961 ataaacatca ttacaactta taaaaggtat aaaatgatat aaacctcagc actccataaa
    22021 ttttttcaca aaaacaatcc cttcaaagta attcacacta attgtaaata ctttgaaagg
    22081 atgttatttg tattccatga cacatgcatc ttatttaagt tttacactct atttttctga
    22141 tgtcttgatt aattgcaagc ggtcttgcga accttgttca agctcatatt ctttatctac
    22201 ttgcttaccg ttttcattta ttaatcttac ggttgcggta atcttatcac catgtttttc
    22261 ggcatctata atttgtggtg aactaatcat cattaaactt cctttagata cacgcttctt
    22321 tacatcatca taaaaagatg atcctttttt tatatatgac gatacaaaat caaaatccga
    22381 ctgattaaac gcagcattat tcgctaaaga atatccagca aagaattcta tcaatttgtt
    22441 cttcaagctg ttttcttctt tttctttctt ttcaacatag tcttcgatat cttcactgtc
    22501 aaaattcaaa gttatctctg tattgtattt taaatcgcta gctttaatcg tcttcgtctg
    22561 tgttgtaaat gttttatctt tcgctttacc agaagctgaa atggtaatat ctttattttg
    22621 tggatatgga ccatacgttt tggaacttga aaatgccatt tcacggtcat ttatagttac
    22681 ttttttagaa ctatcattta attttgtatc gccttttaaa gttacagtta tatttgcttc
    22741 ttcaaaatct tcagtaacat ctaccgtttc agaattactt tgtctaaaat caaattttaa
    22801 atggcctgca aaatcaccgt tctcagttga tttcatagct ggaattctat atgtccccgg
    22861 tataaaatta cctattggcg tcactttatt tgcttcagct ataaccattt ttttcttacc
    22921 accagattta aactcatatt ttgttttttc tttcggttta acaattggtt gcttggtagg
    22981 tgcagtaaag ctcatattat cgaaaaagat ataacgagtg ccatttttac ttacacgtaa
    23041 tatattttga ccagatctgg tttgaatata agaagctacg ctggtcttac tcttattcaa
    23101 tttatgtacc gtatttttaa ggtcgctgac aaattgctta agcccaactt catctttgat
    23161 atagttaatg tatactttcg cttcttcaga atctacttta ttatctttag tacttaataa
    23221 tgttgctact ttttgtttat cattattctc aatcgcattc actaatattt tagtttgcgc
    23281 ttcaggtgaa ttgaagtttc ttagtaaaaa gaacaatata ataattaaga ttaaaatgaa
    23341 aaaaccaatt gcccaaggca ccatttttct catcttgatg ttattagttt gtatatcttc
    23401 atcggttgac tttctatata atgcttgacg actatcaaat ttatgtccac attgtgtaca
    23461 tatctgtaca tcatcttgtg cttgttgtcc gcacttcggg caagatttca tactttcacc
    23521 tcaattctgt tcctcttcaa ttgttatatg tatatcacaa aaattatttc attattttac
    23581 cattattatt ttacaaatat tatcccaaga atacaattca agaaatgatt aactttactt
    23641 tagaattgta ccttattaca ttatttatga aagtactctc tcaattataa ctaaaaagaa
    23701 ggtgttcaat acatacatat ttagtcttat atttgaacac cttcaaaaac ctatttatga
    23761 ttgctatatg ttttaatgcg atgattgatg acttctaata cttgccttac attttcaata
    23821 tcttcagaat ttaaatcatt agtaatatct tgcgcaatat ctgtcataat cgcattacgt
    23881 tctttcaaat atgctctacc tttgtcagtt aaggttatga atttcaaacg ttgatcaata
    23941 tttaaatttg gtttatctaa cttaactaat ttagcatcga ttaacttttt aattcgtcgg
    24001 cttactgcgg ccttgtttac accttgtctt tgcgtgattt cactaattgt caaaggttct
    24061 ttatttaaca tacctaatac gttagactgc tctaatgaaa tttcatattc attttgtaaa
    24121 tctttcaaca tttttgcagt taatgcgtta acgttattta taaactgctc taaaaattga
    24181 atatggtctt gtaaatgttt taccataatt atttctccct aattactatt tttataaagt
    24241 atcctcagca atcattgtat cgcacatcta aaaaacacaa aaatattgac ccatatataa
    24301 tataacaaat taagacttac atgttgctac gttctccttg ctttaataaa ttaaatcatc
    24361 tacatttata cttaatattt attataagcg aggtgtcagt atgttattga atttattatt
    24421 attatttata cttatcgtta tttgtccgtt aattttcaac tatactctga cgttaaattt
    24481 aacatgctac atcttagttg tcatatcgat atttttgtca ctcatctata gcatcatgac
    24541 ctatactttc ccttggtcta tgtttataac atttataata atcagtatta tcatgctatt
    24601 caaacataga tatttatttt ctcatacttc tagtcgctta tttattaaaa aattattatc
    24661 tttttcatat aaatttgtac tctacacatc agcacttcta tttataagta cgattcagtc
    24721 acctattgtg aaaggtttgt ctatgtggtt agctatatta tgcctttcct tgttactaac
    24781 ctttatttgt tatctcgttt ggacagtatc atatagacat agatcataca acaaagaagt
    24841 tgatatcata attgtgttag gtgctggtat ttttaccgaa tttgtcacac caatgcttgc
    24901 agcgcgttta gaccgtgcac ttgatatcta tcaacaacaa gtatcagcaa caaagattat
    24961 tgtatctggc ggacaaggac cagacgaacc aattcctgaa gctttagcta tgcaacgcta
    25021 tttgattgca catggtgttg ataaaacaga tatactaatg gaatctcact ctataaatac
    25081 atacacaaac tttttatatt ctaaacaaat catcaacaat ttgtatcatg aagcagttaa
    25141 aattgtttgt gtaacaagtc agtttcatgt attacgcgcc ttacgactag cccaaaaatt
    25201 aggtttatct atcgatggtg tcggaagtca tacaccatat cactttttct tacatgtgct
    25261 cattaaagat tatctaggcg taatgtatca gtatagattg ttattaacgt tatattgttc
    25321 aagtagctgg tttatatgtc tatacgctgc ttttatttat aatagttaac ccacaaataa
    25381 actattatta taggttgttt ctaatattgc gtcaaactat ctttaaatat gcgttaatcc
    25441 ttgattagac aattgttata ttgaaaataa ataaactaaa gcacgtcatc attttatata
    25501 atagtgacgt gcttttttgt aaacccaaat cgtattctgt tatctaactt ttatactact
    25561 atgtcttaaa tcattaacat ttagcgtctt tacgagccac taatcagtta ttttgccatc
    25621 ttctaattca atcactcgat cagcatattc aaataatctt cgatcgtgtg taatcataat
    25681 accaatcatt tgttgttctt taatttgttg acgtatcatc tcaacaactt ttgttgctct
    25741 atcggcatct aaacttgctg tgggctcatc tgctaaaatg attttcggat tattcataaa
    25801 tgctctcata atcgcaacac gttgcttttc accgccagat aactgatgcg gatatacatt
    25861 caagcgatct tctaaaccaa tattttccaa aagttgtatt gctcttgttg aactttgttg
    25921 tttggtcatt cccgcttctt ggcctacgag cgtcaattgc tctatcactt ttaaataagg
    25981 aactaaatgt gaagattgaa aaataaaccc aatatcttcc aatcgtaaat cactaggacg
    26041 atgctgttta tcaaataatg gcgcatcatt gtaaagcact gtaccactcg tttgacttaa
    26101 caatccacct aatatcgtta gcaatgttgt tttcccagaa ccagaggcac catttaaaat
    26161 gacaaattcc ccttgttcca cttcaaaatt aatacctttt aaaacttttg tttcagacaa
    26221 accttctccg aaatttttga cgatatcttt aacaactaat gccattattc tgcacctcca
    26281 attgcttcga taggatccac tttaaataat ttgacaaatg atagtgaggc acctaaaatc
    26341 gctactaata taaatatccc caccatcaat aaaatatttt gcgttgttaa ataaaaaggc
    26401 atcgttacag gcatcataaa tgatagtcct actatgatga tcacagcaat acctacccca
    26461 attattgtta gtgttaaaat ttgtaaaact aacgcactca ataaatgtct tgtcttaata
    26521 ccaattgctt tcaaaatgcc gatttgtgat attttttgaa tcgtcataac atagaaaaat
    26581 gcacttagaa cgattgctgt aatagtaaac aaactaacaa tcatcatatt taacggtgct
    26641 tgctctgctt gataactcgc aatattacct gttaaatctt tttcactcac aacttgaacg
    26701 tcatttattt tattaagctc atcacgttgt tgttgcgtta aatttttcac tggataaaat
    26761 gccgtattaa ccttattcaa tgcattaaat ccgttatcgt tcaatagcac aatggaacta
    26821 tgcgcataca ttgtgtcgtt taaaatacca gaaactctat aactagttga attattttta
    26881 aaatgtaatc tatccccgac tctaatgttg tctgcagcta acttatcatt aatagcgacc
    26941 tcatgagcat ttttaggata atcacctttt ttaagttgta tgcgttgttg tttaacgtca
    27001 ttcattgtaa tcacatcttg ttctttatta gataatttca atgtttgaat attcatttta
    27061 tatggttctt gatgaattac ctttttaatt tgattctgtt gcgtatcact aagttgcgat
    27121 ttctcaattt gcggctcttt cattttttga acaacatatt catcattatc aaagtgttca
    27181 aataacgaaa tattctccct accaagccct tgagctaaac cactaataaa taacaccata
    27241 atacttaata aaagaatgat taatgtgatt aaaatataac gaaatttgta aaacataatc
    27301 tcttttatcg ctaatttcat atcgattcac ttctccctat ttcttcttta gcgtcagtat
    27361 aaggttgaaa tatgaactca atatgaacaa ttgttttttt acgcaaaaat attttacatg
    27421 tataataaat gaaaaagata agggagttta tagctatggt gcaatgtctt gttgtcgatg
    27481 acgatcctcg tatcctaaat tatatagcta gccatttaca aacagagcac attgatgcat
    27541 acacacaacc aagtggtgaa gctgcattaa aacttttaga aaaacagcgt gtcgatattg
    27601 cagtggtaga tattatgatg gatggtatgg acggctttca attatgtaat acattaaaaa
    27661 atgattatga tataccagtt attatgttaa cagcgcggga tgcacttagt gataaagagc
    27721 gtgcgtttat aagtggtact gacgattatg taaccaaacc ctttgaggtt aaggaactta
    27781 tttttagaat tcgtgcggta ttacgtcgat ataatatcaa ttcaaattca gaaatgacca
    27841 ttggcaactt aacgctaaac caatcctatt tggaactcca agtatctaat aaaacgatga
    27901 cgttaccgaa caaggaattt caattattat ttatgcttgc agcacgtcct aagcaaatct
    27961 ttactcgtga acagataata gaaaaaattt ggggctatga ttatgaagga gatgaacgaa
    28021 cagttgacgt tcatattaag cgactacgcc aaagattaaa aaaattaaat gccacactta
    28081 caattgaaac agtaagagga caaggctata aggtggagaa tcatgtttaa aacactctat
    28141 gctagaattg cgatttattc cattacggtt attttattta gtgcattaat aagttttgta
    28201 ttaacaaatg tttactatca ttataattta aaagcatcta atgacgcgaa aatcatgaag
    28261 acgcttaaag aagcaagaca atatgaacaa tcagctaaac caacgcacat tcaacaatat
    28321 ttcaaacatt tagggcaaat gaattaccaa ataatgaccg ttgatcaaaa aggtcataag
    28381 acattttatg gggagccgtt tagagaagat actttatcac aaaatgctat taacaacgta
    28441 ttaaataata aagattacca tggtattaaa gataaaccat tcgcattatt cgtaactgga
    28501 tttttcgaca atgtaacaga taatactgtt ggtattaact ttaagacaaa agacggttca
    28561 atagcagtat tcatgcgccc agatattgga gaaacattta gcgagtttag aacattctta
    28621 gccgtcttgt taatgttgtt attatttatc tcgatttcat tagttatcgc atcaacctat
    28681 tcaatcattc gtccagtaaa aaagttaaag ctagcgaccg aacgcttaat tgatggtgat
    28741 tttgaaacac ctatcaaaca aacacgcaaa gatgaaattg gaacattaca gtatcacttt
    28801 aataagatga gagagtcatt gagacaagtt gatcaaatga ggcagcattt tgtacaaaat
    28861 gtatctcatg aaatcaaaac accattaaca catattcatc atttattaag cgagttacaa
    28921 caaacttctg ataaaacatt acgacaacaa tatataaatg atatttatac cattacaacg
    28981 caactgagcg gattaacaac tgaattgttg ctcttatccg aattagataa tcaccaacat
    29041 ttattattcg atgataagat tcaagtcgat caactcatta aagatattat tcgacatgaa
    29101 caattttctg ctgatgaaaa gtcgttaatc attttagctg acctagaatc aatcgatttc
    29161 ctaggaaatc aacgtttgtt acatcaagca ttaagtaatt tattaataaa tgctattaag
    29221 tatacagatg ttggtggtgc cattgacatc gctttgcaac atagtcacaa caacatcatt
    29281 ttcacaataa gtaatgatgg ttcaccaatt agtccacaag ctgaagcacg tttatttgaa
    29341 cgtttttata aagtgagcaa acatgataat agcaatggtt taggtcttgc aattacaaaa
    29401 tccatcattg aattgcatca tggtacaatc caattcacac aaagtaacga gtatgtaacc
    29461 acctttacta ttacactgcc aaataattca cattaatctc tacctcctga aaaaacattt
    29521 ctgtttttat tacaggaggt atcttttata ttaattaacg ctttctagcc acttaacatt
    29581 taatttctac cattcaacaa aatttaaata tatcgatggt catttatggt ttaataattt
    29641 tgaaggaggc attaacctat gatgaaactc aatttattta tcaatgcaac tgagacggaa
    29701 tcttatattg atatacatgc acctaaaatg aatgatcacg ttcaaagtat tattaatgca
    29761 gtcaatgatt tagacaaatc acatacatta gtcggataca tagacaaaga aatccatatc
    29821 attaatgtat cagatgttat aacattccaa gttattaata aaaatgtaac agccattaca
    29881 agcaatcaaa aattcaaact aaaattacga ctttatgaac tagaaaaaca gttaccacaa
    29941 catttcattc gtatttccaa atcagaaatc gtcaacaagt attacattga aaaattatta
    30001 ttagagccaa atggacttat acgtatgtat cttaaagatg cacactacac ctattcttct
    30061 agacgttatt taaaatctat aaaggagcgc ttatcaatat gaaaaatttg aaaaactcat
    30121 tatttattag cttaatcatt ggtttgtccc tttcactgtt ctttagtatg ttatttgcag
    30181 acggcaaata ttatccactg aacccacaat caactattgg catattgtat tataatcatt
    30241 tcacagaaac taccgtaatg ttgatttcta tcattttatg gttactcata ggcgtcgtct
    30301 ttttccttgg agattttatc tttaaataca cagattgggg cattactaaa gcaactatag
    30361 tgcatttcat aacaacgtat gtcggattct tacctttagc aatacttgcc ggttggtttc
    30421 cactaacaat aaattcccta atcatattta caattatctt tattgtggtt tacacattga
    30481 tttggattat tcaattcttt aaaaacaaga actacgtaga cactattaac gagcaactga
    30541 aacaattaaa atgattttta ttaaaattat aaaagctata cattgcatta aagtagtctc
    30601 ttctgcaatg tatagcttta tgttgtattt attttaaata cgcatgaact gaataatatg
    30661 tttttactat tttcaaatta aattgtaact gcaactgtcc tttacaacat caacttatca
    30721 tgataaaaac ctaacgaaat gcattttcaa atattttatt cataatttct gctacttctt
    30781 taggactctc tttatatcct cgtttgaccc aatcttgtaa cacaccaatg attgcattac
    30841 tcataaaaat aagtaaaaaa tacttttcct tcgtcgttaa catttttgta tttaatactg
    30901 gtacaacatt aatttcgata cgttgttgta gtgatttttt tatgacttga tgtaatttat
    30961 aagcactctc atcacctaat aacatcaata tgagctgtcc ttcacttagc caataataaa
    31021 tcatcctttt aaaaaatact gcttgtgtca taggcctctc tttaatgaac ttctttttag
    31081 caacttttaa caatgtatta agatagctgt atataaaatc atctttagtt ttgtaatgtg
    31141 tataaaaggt tgtccgactt atttgactct tttcacatat atctttaaca gttatatcat
    31201 tatatgcctt catttttaat agatttacca ttccatcatg tatgcgattt atcgttttcg
    31261 ttacacgact atccgtaaaa gctgtttgat ccatatgccc cacctttttt ctgaacacta
    31321 aaagcaaata tgttcactat ctgttaatat tttattcgca atcttaatat acgcttaaga
    31381 tgatatataa ataaagtgaa atgtatctca atttaggagg ggttgtcatg gacgcaacta
    31441 tagcgaagtt ggataaagtt gtaaaaacgt ataacaagca tcacgtatta aacgaaatta
    31501 gtatgtcaat caataaaggt gaactgctag ggttaatagg tcctagtggt tctggtaaaa
    31561 caacaacaat aaagtgttta ctaggtatgg aaaaagtaga ttcgggatct gcagaaattt
    31621 tcgctcataa gatgcctaat agcaaagctt taaatcgatt aggctatatg gggcaaactg
    31681 atgcattata cgaaaactta actgcttatg aaaacctaga gttttacggt cgtttgtcag
    31741 gactgaaagg aaatgtatta aaagataata ttgaaaaaaa tatcgttcta gtgaatttag
    31801 agcaagcgtt aaataaaaaa gttgcacagt tttcaggagg catgaaacgc cgattatctt
    31861 tagcaataac attgttggcc gaaccagaat taatcatatt agatgaacca actgtaggca
    31921 ttgaccctaa attgcgccaa caaatatggc aacaattcaa gcaaatgacc aaagacggaa
    31981 agagtgtcgt catcacaaca catgttatgg atgaggcgga acgttgcgat aaagttggac
    32041 ttattgtcga cggaagaata tttgctatag atacgccaac caatttaaaa caaagattta
    32101 atgtagatac aattgaagcg gtatttatta aagctgagga ggttcgtcaa tcatgaaaat
    32161 tttagctatt gttaaacggg tattaaaaga aatgttacgt gataaacgta ctcttgcgct
    32221 gatgtttcta gcaccaattt taatattaac gcttatgtat tttattttta acggtgatga
    32281 aaacgatttg aaaatcggta tcgatacatc tgtttcatca aatataacaa aacaattgcc
    32341 atcatccgac ataaaaactc aaacgttcca ttctcatgaa aatatcagat ctaaaatcga
    32401 gaataatcat cttgatggtt atatttacca agaaaatcaa acattacatg tcatttatac
    32461 aaatgaagac cctaacaaat ctaatatgat caaacaaatg attggcaaag ctatacaaca
    32521 agataaaata agcagtataa agcatctaat tgaaaaagca cctccgacca tgaaagcacc
    32581 aaacaaacaa gatattaaga tttcgcattc ctatttatac ggtaattctg atagtactta
    32641 tttcgataaa atgtttccaa tactaatggg cttctttgta tttttatttg tatttctaat
    32701 ttcaggtata gctttattac gtgaacgtac aacaggtacg ttagaacgtg tattatcaac
    32761 ttcaattcgt cgaagtgaaa tcgtccttgg ttatctgatt ggctatggta tattcgcaat
    32821 cattcaaaca ttaatcatag tcctattttc aatatattta ttgaacatta atttagcagg
    32881 tagcttatgg tatgtaattt tgattaatat ttgtttagct attacagcat tatctatggg
    32941 gattttcatt tcaacgtttg ctaattctga gtttcaaatg attcaattta ttccactagt
    33001 tgctgtacct caggtattct tttcaggaat tttcccactt gaaaatatgc ctgattggct
    33061 aggtaacatc ggctatctct tccctcttcg atatgctggt gatgctttaa ctaatattat
    33121 gataaagggg caaggttgga gtaatatatg gttcgattta ctaattctaa tgatttttat
    33181 catagtcttt attatcttaa atattgttgg tttaaaacga tacagacagg tataaatgct
    33241 acaaaacttt taaatgactt caatcaagat aagcttctaa atataaagca ctgataataa
    33301 aaacaaccac taaaaaacgg taatgtctat cgcattaaaa aagacattac cgtttcgttt
    33361 attatttaac ttgtaaatac ttagttactt cttcattaat tttgtgatat aaatcctcat
    33421 gatctgttaa gcgataacca aatgacggca ccatttcttt aacctttggt tcccatcctt
    33481 tgaattcatc acgatagcat cgctgtaaaa catcaaacat aatatctaca gctgttgacg
    33541 caccaggtga tgcaccaagt aatgcagcta atgtgccatc atctgacgta atgacttcgg
    33601 taccaaattg taagttacct ttagaatcct cagtatcctt gattacttgg acacgttgcc
    33661 ctgctgtaat cacttcccaa tcttcatttt tagcatttgg gaaaaagact cttaaatcat
    33721 ccatacgctc atcattagat aacatcaatt gtgacactaa atacttcgta agactcattt
    33781 ctttgatacc tgcagataac atcgtcacga tattatttgg tttaaccgat ttaattaaat
    33841 ccatatgtga acctgttttt aaaaatttag gtgagaaacc tgcaaatgga ccaaataaca
    33901 atgaacgctt gccgtctaca aaacgtgtat ctaagtgcgg cactgacatt ggtggcgcac
    33961 ccactgctgc ttttccgtac actttagcat gatgacgatc aatcacttct tgatttgtac
    34021 agcgcaggaa taatccactt accgggaaac caccaatatg ttttgattgt ttaattccag
    34081 tcttttggag taatggtaaa ctcgcaccgc cagcaccaat aaatacaaaa tcagattcat
    34141 atgttgtcgt ttcgttagtt tctaaatctt taactttaac tagccatgcc cctgatttct
    34201 gtttcttgat gtctaataca ttctgcttat attgaatttc cacaccacgt tgttctaaat
    34261 tatcaaataa ctttgcagtt aacgcaccaa agttaacatc tgtaccagtt tcatcataag
    34321 ttaaagcaat tggttcatca gacttacgac cttcaatcat taacggtacc caagatttca
    34381 tttcttcttc atcttgcgat aatttcattt tttcgaataa aacacttttc tttaacgttg
    34441 caacacgact ttttataaaa gctacattat cttcgccaat gacaaaactc atgtgtggca
    34501 ccgcttgaat aaagcgatct gggttatcta attgtcctgt tttaactaaa tatgcccaaa
    34561 actgctttga aatttggtac tgctcattta tcttaattgc tttactacaa tcaactgtgc
    34621 catccttacc ttcttttgta tagttcaact cgcaaagtgc tgaatgccct gtaccggcat
    34681 tattccatac atttgaactc tcttcgccag gttgtgctaa tttttcaaac actttaatat
    34741 ttttctcagg tgataattct ttaagtaatg ttcctaatgt tgcactcata ataccgccac
    34801 caattaagat gacatctgtt ttgctatgtt gtgttgtcat aacaaataca gtcccccttt
    34861 ttaaaatgaa taatggaacg ttcgacaaat acgacatatt aataccactt tgaatcaata
    34921 agtgtctcaa taggctccca tagtgatgct ctattactat ctactatgta tattaatatt
    34981 ttataataac gaaactactt taattatata ctttatgtgc gatagcacaa agacaaaacc
    35041 acaaacctta acagctatca accaatttaa tttgattgct gattactcac tcttcatttt
    35101 aacataaagc tctaccatta ttataatgtc aaacttcttt cattaataat ccattaaaaa
    35161 aagatgagat gttagaaaac atctcaccct ctgtatattt atattttgaa atacgttttt
    35221 ttatagtaat gacaagatga aagtccaaat acagatgaat attagtaaac atacactgta
    35281 tttcaatgtc atttttaata attctgattc cttaccaact tgttttactg ctgcagttgc
    35341 aattgcaatt gattgtggtg aaatcaattt tgccgctaca ccaccaactg tattagcaga
    35401 tacaagaagt gaaccacttg ttccaatttg ttgtgcaaca gaagcttgaa ttggtgcaaa
    35461 taatgagttg ttatttacaa ctgatcctgt cataaacaca cctatccaac ctaagattgg
    35521 tgatagaact gggaagacat tacctgcttt agcaatacct tgacccattg ctgcacttaa
    35581 accaccataa gttgtgattt tagaaattgc taagatgaaa caaattgtaa ggactggtaa
    35641 ccataattct ttaaatgtaa caccgaataa tctacctgca tctttaaagt taaccttttt
    35701 agacattaaa attgtaataa taatagttaa taaaatagct gtacctgttt gtccaataat
    35761 atttaaagtc aaaactaatg gtttatgtgt aacttcactg actgttccag gtaagttgta
    35821 tttaaatact aatgatgata aagcaccatt tggtaagaat aagtttttaa agaatggcgc
    35881 actccaaatc attacaatga ctgttaatac aatgaatgga ctccatgcat gtaatactgc
    35941 ttttgcagaa tgtgcttttg caggttcaat ttcttcatct ttattaacac gataaatgtg
    36001 ttttggttgg aattttttag aaaatactgc taatgctaac attgttaata acggtggaat
    36061 aatatctgct aattcaggtc cactgaatac tgttaataat ccttgagtaa gtgtataagt
    36121 gattgaaact actaaaattg ctggtaatgt ttctttaaca cctctaaaac catcaataat
    36181 aaagataagt aagaatggaa taatgaaatt tatgattgcc aatgttaaag ttgctgattg
    36241 agaaacacct aatactgaaa catctccagg taatttcaac gtttctacaa cacctacagg
    36301 gataccaatc gcaccaaaag caccagacgc tgcatttgcg actaaacata acatcgcagc
    36361 ttttaatgga ttaaatccta attgtgttaa taaaagtgca caaattgcaa ttggtacacc
    36421 aaatcctgct gcaccttcta aaaatgcgtt gaatgcaaat ccaataagta aaacttgaat
    36481 acgttggtct tgtgaaatat ttgtaatact atcttgaatt gttaaaaatt gtccagattc
    36541 aacagtaatt ttgtataaca atactgccat cataacgata tagccaatcg gaatgatacc
    36601 ttggaagaaa ccttcgacta ctgcaccaga agcgatacca actggcaatt tgaaaaatgg
    36661 tattgcaatt agtaatgtta caacaagtgt tgtaatggct gcataaatac ctttcatttt
    36721 aaaaacagtt aaacatagta aaaacagtac aatcggtatt gctgcaatta aagacgataa
    36781 taataaatta tcaaatgggt taaacgtatt tactaacata ggctgactct tctttccata
    36841 aagtagtagt gtaattactt cattaaaatc atgctctggc tatagcattt tgttatcgat
    36901 aacattttac agaacagtga gattaatgtg atttttttca caattaaaat ataccatttt
    36961 ttcagactat taacaatatc actttcctat ttaattgttt tatttttcat tttaaatctg
    37021 ttcatcaaaa tgaattgtac ttaatgtaat gaagtaactt atactattca tgaattttac
    37081 ataagaccgt gctaaaataa ggaagatact acgatgagaa atggaagtta tagcaatgat
    37141 taaacagata aatgtttcta atatgcaaaa gtttgaatct caattaatga aagctcagtc
    37201 tgaaggttat acacatgtcg ttccatatgc caatgagata atgatttatc aatctatgtt
    37261 agatgcggtt caattatatc ctaagtctat cgtggttgat tatactgtgg atggacaata
    37321 caaaaatgat tgtcactatt tcggtcaatc aacgatcaac attgccgatt gggctcaaaa
    37381 caataattac tatcctaacc tgatatatgc gattcaacag actcttgatt taatacatta
    37441 ttactctgta gaaacgattt tcgatttagc tttattgaca cttctgaaag gtgatttatc
    37501 aatcgatggt catgtcgttt ttgattttaa agccccttta gcaacaagtg cttcaatatg
    37561 ggaaactatt aaaactattg aagattttga tatgatgtct cagttttatt tgaataaaat
    37621 ggcttatatt gatcatcatc ctataccttt tcgcaacctt tttatcgagg attcagaaca
    37681 acttaattcg ccagataatt ggttgtattc taccaagttt atgctaccta aatggttata
    37741 caaaatagca aagcaacgtg ctgataacaa acaattacaa aacttcggct tgtatacgaa
    37801 gcaaccaaac gttttaaaag atcacatcgt ttttatcggt gatcatcatc aatatatagg
    37861 taattcaaaa tatttattta cttacttcgt taaacataat ccaatgactg cctgttattt
    37921 tgttactgac gatcgtcgcg gaccacattt catatcacct aagtctgaaa aagctgacga
    37981 attgattaac agcgcacgcg tagttttagt tgaaaatgat atacctgaaa cgttacaacc
    38041 aaacggtact ttaattcaat tacatcaagg cacaccaata atgcaattat ttttagatag
    38101 taaagagcct attaaaaata tagaaacacc tttttatcgt gctaaaaggt ataatcgctg
    38161 gttgcaattc gattatgtta tacattctgc tgatgatatt agccactttt atcaaacggc
    38221 ttttcctagt caccaagcaa atgtattggc ttacggtaat cctaagcacc aatatttact
    38281 acaaaagcgt aacgaaagta ctactcaaca acagtataag aaatcgttta aaataaatga
    38341 tcaaaaacca gttttattat acgcacctat tggattagtg agtgcgcaac aattaccact
    38401 atcagatgct ttattcaaag cctatcatgt tgtggttcag ggtattgatg aaacgatgtt
    38461 accagaagag gcgattgttg caccaaaata tcttagtgct caagacttaa ttctaatgtc
    38521 tgatgtcgtt atcactgatt actcaaatat aatatttaat gcgatggcta tagacaaatc
    38581 agtagcatta tacactccaa atcacagtca atatattgag tctcaaggtg ttaacgaaga
    38641 tatttggcgt catctatcaa aaatttggta tacagaccga caattattaa ttaataattt
    38701 aatttcccag gcaataccag tgattaaata tccacaaata caacataaag aacaaccatt
    38761 agaatctatt tcacaactta tattgtctaa gatgacatct aatcaatagt gtttaaattc
    38821 atcagtggct gtgaatgagg tttaaaagta ctataaaacg taaactttta tactttaaaa
    38881 tacgcaaaaa aaacggtaaa ccctaattca tattatagag tttaccgttt taatttttta
    38941 acttgcatca taattacatt aacattattg ttggtagttt ggatcagtaa ccattgcttg
    39001 tccagtataa tcaaccgtta caattgaata ttttccattt gcatttgggt ctttaaaact
    39061 aaacacatac ttataattac cattatgttc ttcaatagag tagtcattat acactttatt
    39121 attactacca aatttatttg cttcattatt agccgcattt aaagctgttt ggaaatttgg
    39181 caattgctgt aaagcttgag ttttatttcc attaaacgga taaatttgac gtgcaaccgg
    39241 cgcggcattt tgtccataat atggtgcaac gtaacttgat ttttgattat tattcgcttg
    39301 attattactt gattggttat tatttgtttg gttttggtca ttgtttgttg catttgaatt
    39361 agattgttgc tggttatcgt ttgcactatt atctttatta tctttgttta cgtcattact
    39421 atcatcttta ttgtctttct tatctttaga tgaatcattt gtttttttat cttgttgttc
    39481 agttttcgct ttatcatctt tttctttatt actgtctttt tgttggtcac tatcttgacc
    39541 acatgcagct aaaaataatg ataatgctag taaccctgta actaatcttt tcatacatat
    39601 ctcctcctat aattcgatat tcattgaata agcttgaaat acatatctac catgtgtatc
    39661 ttttcatggc ttgttaccaa agacgtcaac attaatatga tctgaattat cacaatatcc
    39721 ataactacaa tctaaggttc tttttattat accctaattt ttgttcatta ttatttaatt
    39781 tttgtgaatt ttatgttttc tataaattta attattttac ttcaacaatt cattacgcat
    39841 ttagcatttc aaggcataca caatatttat tactatgatt tcattttatc tgctgcaaaa
    39901 acaatcatta taactctttt tccataatta aatctgtatc cgttacatca cctgtttgaa
    39961 aatgatgttc accaaccact ttaaatccat gacgtttata aaatgcttga gcacgaggat
    40021 tatgctccca aactcctagc caaattttat gtttattatg ttcttgtgca attttttcgg
    40081 ccaattctat caattgtgaa cctcttccgc caccttgaaa gtctttcaaa aaatatatgc
    40141 gctgtacttc taaataggtt tcccccattt cttcagtttg agcactatta atattcatct
    40201 ttatataacc aacattcgca ccatcttctt gataaaaata atgaaatgaa tctacatggt
    40261 taatctcttg tgtaaatttt tctacagtat aattgtcttt aaaaaattga tcaaaatctt
    40321 tgtcatcata gtaagaacca aacgtgtcat aaaatgttct agttgctaat tcaactaatt
    40381 caccagcatc ttgttttgaa atttctttga ttatcccagc catataaatc ctccaataaa
    40441 cagtgatcga atcaaaatat tacttatgtt atttttcagc caaaactatt taaaaataca
    40501 ttaacacaaa tcaattacaa attgtattga ttgtgtgtaa catcaataaa tgatacattt
    40561 attccagtaa aatggccgta ttttcaaaag agaaaaagag aggatgtatc gttgtgatag
    40621 aaacatttaa agcgtttgta attgataaag atgagagcgg taaagtgaca ccaactttca
    40681 aacaattatc gcctactgat ttacctaaag gagatgtgct gattaaagta cattactctg
    40741 gtataaatta taaagatgct ttagcgactc aagatcataa tgcagtcgta aaatcgtatc
    40801 ctatgattcc aggaatagat ttagctggaa caattgttga atccgaagca ccaggatttg
    40861 aaaaaggaga acaagtaatt gtaacgagtt atgacctagg tgttagccat tatggcggtt
    40921 ttagtgaata tgcgcgtgta aaatcagaat ggattatcaa gcttcctgat actttaacat
    40981 tagaagaatc aatgatatat ggcacagctg gttatactgc cggtttagca attgaaagac
    41041 ttgaaaaagt tggaatgaat attgaagatg gtcctgtact cgttcgcggt gcttcaggtg
    41101 gtgtcggtac tttagcagta ctcatgctta atgaacttgg ttataaagtt atcgcaagta
    41161 caggtaaaca agatgttagc gatcaattac ttgaacttgg tgccaaagaa gttatcgatc
    41221 gacttcctgt tgaagatgat cataaaaagc cactcgcatc atcaacttgg caagcttgtg
    41281 tagaccctgt tggtggcgaa ggtattaatt atgttacaaa gcgtttaaat catagtgggt
    41341 caattgcagt tattggtatg actgccggta atacttatac taattctgta ttccctcaca
    41401 ttttaagagg tgtaaacatt ttaggaattg actcggtatt tactgctatg aaattaagac
    41461 agcgcgtttg gcgtcgtctc gcaaaagatt taatgcctga aaatttacat gagatcaagc
    41521 aagttattac atttgatgaa cttccagaac aacttaacaa agtaattaaa catgaaaata
    41581 aaggccgcat tgttatcgat ttcggtgtag ataaatagta ttcatgaaaa agacatcccg
    41641 ttatgcgaga tgtcttttta tttgttgtgg attattaaat ttccgatact tcatcaatta
    41701 acattttact ttagtgtatt ttggaaagcc atgtattttc agcacctatc atacctacac
    41761 attaagcaaa ataaatgttg attcgtttac aattcatatt taatttctct ttctatatac
    41821 atcaaaggca tatattgccc aataaacgac tgtgaatgca caactataca aaataactct
    41881 ctcaatattt gttaaaaata aatagatcat taaagctgat aacacaagtg caacaaaata
    41941 atatattata gcttgtctta atgtatcgat tttcattgtt ctaactccct tagttacaaa
    42001 gtcgaaaatt ctatatcata tcaacttgaa ctttaccata aaacacacat ttttttaata
    42061 tcattactta gaaaaacaaa aacatactaa gttaagctgt gtagaaaact cagtatgttt
    42121 atcggtacga tttttcattt ttaaaatttg atatacatac cgcctgaatc tggttcggta
    42181 ggcataaatc caaattttgt atataattta tccgctgggt agtctgcgat cagactaacg
    42241 tatgcacttt cgacagatac atttttaata tacttcataa tatgttccat aatttgactg
    42301 ccgtaacctt gaccttggta acttttcaaa actgcaatat caacaatttg aaaaacagtt
    42361 cctccatcgc caatcactct acccatacca attaaccgat cttcatcata caaggttact
    42421 gtaaataagg cattaggtaa tcctttttca gctgcttcgc gcgtctttgg actcatacct
    42481 gcattaatcc ttaatgcgca ataatcctcg caagtcggaa tatcatatgt cactttaacc
    42541 attatttacc ccacttttca tcacacaata tatcaaacta gtataaatgt ttatttacaa
    42601 tagtcttatt cgcttcttta aacacttcat gatgacttga aacataaccc tctgcattcg
    42661 catctggttg gatatatgtt ttagcaaggt tcgctgcatt tgcaccatca ctaaatgcac
    42721 ttgcaattag atgtgatttt gcatcatgat aaacaatatc tccacacgca tagataccag
    42781 gtatactagt tgtcgtatta ccaaatcctt taacacgaca atcatcatgc atatctagct
    42841 ttgaagatgt ttcactcaat aatgtattac aacgatcaaa accatgacta ataatgacat
    42901 cgtcaaattt aactgtatgc gtatcaccac tttcaacatg ttccaaaaca acttcactta
    42961 tatgcgtttc atcatcattg ccgaccaagt atttaatacg tgttttcggg catagtttca
    43021 catttaaatc tgtcaccagt gttttcatcg cttcatgacc acttacatct tcttttcgat
    43081 aaacaactgt cacgctttta gcaatcttgg caatatcatg cgcccaatct aatgctgtat
    43141 ttcctccacc tgatattaat acatctttat ctttaaaacg tctgtaactt tgtacaacat
    43201 aatgtaaatt agttaattga tatctctcta cacctttaac atctaattgt tttggattaa
    43261 taatacccgc accaattgca atgataactg ctttcgatgt atatatttct cccgcttctg
    43321 tttcaacttc gaaatgacgt tctgcctttt tcctaatatc taccacacgt tcattcaaat
    43381 gaacttccgg tttaaaatat aatccttgct taattgtatc ttttaaaatt tcatgacaag
    43441 gttttggggc aatgccgcca atatcccaaa taattttttc agggtaaatt ctcatcttac
    43501 cccctaattc agattgaaca tctattaatc ttacagacat atctcgcaat ccagcataaa
    43561 agcttgcata caaaccagac ggaccgccac caatgattgt aacgtctttc attatgtgcc
    43621 tcctatgact ctctatattc atttctttca ttaacgcgct caaattgata attattatca
    43681 tttaaagaca ttatactatt aatatttata ttgttaaaat aaatcgcata gttagccatg
    43741 aattatcaat aactatccca tcacaatata aaaacacacc tttcaaagta cgaaacaaca
    43801 atgttccttt gaaagatgtg tatatttttt agtactagtt atattatttt ttaaaagact
    43861 catcacgtgg ttctttaaga attgcttgtc ttaaaaggaa aaatagcaac aataaacctg
    43921 caagcatacc tgtgtgccca atacctgcaa agcctgcaaa tgcttctgga gagtatgatt
    43981 taccagtgac ttggaagaat ccttttgtca ccatcatacc tatagtaacg ataacaccta
    44041 tgttatatac atagaagaac cagttaaata agtagtaact tgataattta aataacttct
    44101 ccaatggtaa taatattaaa aacataaaca tacctaaaat aagtgtatgt gtgtgtacaa
    44161 gtgataattg tgttgtacca gtaaaatcat atgcttttgt tagctctcta tagaaaaatc
    44221 cactaaataa acctatgatc atataaaaaa gaaatgaata taataaccta cgcattttga
    44281 atcctccctc accttttcat tatatccgat tatacctatt ataacagtga caaaaaagcg
    44341 aagatatgac acaactgaat ttggtttagc acatagtatg acagctaaaa taactttaca
    44401 tcaagtacta tacaaataaa atagctatac catgacgctc gctacaaacg tcttgtatag
    44461 ctatattcct atttattaaa ttatgacggc acttcagtac gttttgtgct atgttttcta
    44521 acaatagctg aaactaaact tgatacagcg ccaaaaatca taaaccctat aaacatccac
    44581 attgtactat ttaattcaat ttgatgattc aagtataata gttctcttac acttgttgca
    44641 tagtgtgtga atggattcca atcatataca tatttttgat aactttcggg caacatttgt
    44701 ttaggtaacg ttacaagttg catactaaag aacattaaaa tgaagaaaat tggaattgac
    44761 ttcataccta gccataccat aacacctaaa ataagaccca cgaaaccaag aatcgcaagt
    44821 gctacaaaaa ttgcgatacg atttggatgg tcaaaatcaa atccttgaac gccttgcatg
    44881 aaataaatat aaacgaagct acctgcaaat gctgcaacaa ctgcaaatat catttgtcca
    44941 attgaagcaa tgatacgatg ttgcacgacg atattgttac tagttctaaa tgcaaagaac
    45001 aataagatag acgttacgat tgaacctatc caaattggca taaacattag gaatggtgca
    45061 ttaccacctg cttggtgatc tttaacttta ttaagttttt cattatccac ttttactgga
    45121 ttcgtcaaac cattgatgtc cgcggcattg actttaacat tttgactcgt taatgtttcc
    45181 aaactttgct tcgtaatttg agcattaata ttatcaccca taccagttaa cacagctgat
    45241 gcaatttgtg aaccttgtaa gcttgatcct tcacttacaa tcgttttaaa tttagcctgc
    45301 ttaacctcta cttgttgatt ccccattttt tgtttcattt gttgaaccac ttgtggcgga
    45361 atttcacctg aagcaacttt ttgttgcatt tcttcttttt tactatccat aactactttt
    45421 tgtgttttac tcatagcatc ttttgaaaag tctttatcaa taatagctac tccaaagatt
    45481 ttttgatctt tcaaatcttt ttcaaggtct ttttcactat caaccttaac ccatttaatt
    45541 ttattagaat cactatctaa taatttatcc tctaattttt taccaatgtt aacattttta
    45601 tcttgaatcg ttgtaccttt gtcctcgttt aatataccaa ttggtaaatc tttcggttta
    45661 ggattatatg caggataaaa agctaaagaa aagattacca agataatcat agttgctatt
    45721 ggtgcaatcc ataataattt attttgaaat atattcattt tattaattac ctccttatta
    45781 gacaatgtgt tgaatatttc gcatgttgtc tattataata tgtaagtggg aataaacaat
    45841 acacaatgtt catcaatacg tttattaata gacaaataca cccacattgt tcaataacac
    45901 aaggaggttg atttattttt gaaagaagat aggcgaatta gaaagacaaa gtcctccatt
    45961 aaacaagcgt tcactaaatt actacaagaa aaagatttag aaaagattac cattcgcgac
    46021 ataacaacac gcgctgatat caatagaggg acattttact tacattacga ggataaatat
    46081 atgttactcg cagatatgga agatgagtat atttcagaac taacgacata tactcaattt
    46141 gatttgttac gcggttcttc aattgaagac attgcgaata cttttgtaaa tgatatactc
    46201 aaaaatattt tccagcatat tcatgataat ttagagtttt atcatactat tttacaattg
    46261 gaacgcacga gtcaattaga attgaaaatc aacgaacata ttaaaaataa tatgcaacgt
    46321 tatattagta tcaatcattc tatcggaggc attccagaga tgtattttta cagttacgtt
    46381 tccggagcaa caatttcaat tattaaatac tgggtaatgg acaaacagcc catttcagtt
    46441 gatgaattag ctaaacatgt gcataatatt gtttttaatg gtccattaag aataatggca
    46501 gaaaaccgtt tgcataaatc aaaccttgat tcactaactt aagtaatact cgcttttcct
    46561 aaatccttta gaaaggaact atatatcatg attacttcat tcagacattc tgaagatata
    46621 gataaacata ttataaaaac accattagat catacagcgt catggattaa tgtagtagaa
    46681 ccagaccgag aagaaattga aaatcttatg gaacaatata atatacctga agactttata
    46741 cgtgaccctt tggactcaga agaaagttcc cgtattgaat atgacgaaga tactggttac
    46801 tcattaatca ttattgattt acctatcgtc aattcaacta atcgtagcgt tctatctttt
    46861 gtaacgattc cattaggcat tattattggc aacggtatta tcgtaacagt ttgtgacgct
    46921 gaaaatgaat ttttagaaaa tttacctaag cgtgatatta atttaaaatt tcacagcaga
    46981 tttgcattag aaattttaac tactattgcc gaccattata atcgtaactt acgattactt
    47041 aataaaagta gaattcgtat tgagaaagaa ctaaaaaata acattactaa caaacaactt
    47101 ttcaaattaa tggaagttga aaaaagttta gtatactttt tagctgcctt aaaaggtaac
    47161 gatacaatta ttaaaaagtt attccgttta cctgcaatta aacgttttga agaagatgaa
    47221 gaattactag aagatttaat cattgaaaat aaccaagcca tcgaaacaac agaattacat
    47281 caacgtatct tagaaagtat cacaacatca tacgcttcct tattatctaa tgatatgaat
    47341 acgattatga agacattaac acttttcacg gtactattaa cgttaccaac gctcgtattt
    47401 agtttcttcg gtatgaatgt gccgttgcca attgatgacc atagttatat atcttggatt
    47461 attgtggtag gtatttcatt aattcttgtc gtaattgtta gtattttctt atggcgaaaa
    47521 cagaaattat aactaaatta aaaggtatga cagcttaaag tttcacccta ttgcatttgc
    47581 aatgactgat actttgatta ctgtcatacc tcttttttta ttctacaact tctttatttg
    47641 cttttctttt agataaaatt aaagtaactg ttatggcaac gatgaatgat attgtcatac
    47701 caacaaagta gtgtaaccat cctgcatgta ctggattgat tgagataaat ccaggcaatc
    47761 cagcagttcc taatgcgatt gctttaacct tgaagaaagc aatatatgct gaaccaatac
    47821 ctgatccaac gatagcgcca ataaaaggat atcttagttt taagttaaca ccaaacatag
    47881 ccggttctgt aataccaagt aatgctgaaa tacctgcggc agatgccaca ccttttaact
    47941 tcttattttg tttaataata aagaacgctg caattgctgc accaccttgt gcaacattag
    48001 acattgtcgc aatcgggaat ataaatgatc cacccgtttt tgtggcatct gcaattaatg
    48061 tcgtttctac agctataaag ctatgatgca tacctgtaat aacaatcgga gcatacaata
    48121 atccgaatat taatccacca attgcaccac caaattcata aagccatgtt aaaccatctg
    48181 ataaccagta acctaattgt cgagtgattg gacctacaaa tgaaaatgtt agaaatgctg
    48241 ttataaaaat agataacaat ggtgttaaca aattatctaa caccgttgga ataactttgc
    48301 gtaacccttt ttcaattgaa gctaagatat aagctgctac aagcataggt aacacttgtc
    48361 cttgataacc tacttgatta atatgcaaac caaatacatc ccaatatgga atagccttac
    48421 ctgcttcaac tgcttttggg aaatcgtatg cgctcattag cgatggatga accaatatca
    48481 tacctaatgc agcacctaaa aacggattgc caccaaaacg ttttgctgca ctaaatccaa
    48541 ttaaaattgg taataatgta aatggtgcat tcgcaaaaac atttatcatt tcagctaatc
    48601 cagcaaattg actatagaca tctatcaatg atttacctga aaagaataaa tctttcgcag
    48661 tcaaaatgtt atttaacccc attaataaac caccagcaac gatggctggt ataatcggaa
    48721 caaagatatc tgaaagcatt tttacaaatc gctgtaacgg attcatattt ttagcagatt
    48781 gtgctttgac ttccgaagtg gttgatgctt cttttccagt taatttttcc agttcactaa
    48841 atactttatt gactgtacca gacccaataa taatttggta ttgtccccca gtagaaaacg
    48901 tccctttaac tacatccata ttgtttagcg cctcttcatt tactaaactt tcatcattta
    48961 aaactaatcg tagtctcgtt gcacaatgcg ccattgcatc taaattctct tctccgccta
    49021 tcgcgttcaa aatatcttct gcggattgct tataattcat atatttagcc tcctaattag
    49081 aaccggttcc atttattcca ctttattgta accggttcca aaaatatttg caacactcta
    49141 ttatcatttt atataaacac ctacaccatt tttgatagcg cattcatttt tattgctata
    49201 ctatatgcat gtatattaac attaattatc ggaggtaatt ttatgaaaga acgtggccat
    49261 atcgaacagc tttggcgtga ggaaaaatat catgtattgt tacacagtca acagtcttac
    49321 caaatgataa ggaatgcttt aaaaacggat ttatcacttc atcaagtcca acaaatgatt
    49381 gatgatgctt tgttaattga accaagtata ggaagtgtat gtaatgcttt tgatcatatg
    49441 tggggatatt ttaaaaaatg tgcgaatgaa gaagaaagac aacaatcaaa actacttaaa
    49501 gctgatttta ttaatggtaa aatcgacacc caaactttat tagatttttt agcagaactt
    49561 gctaataaat atgatgttca atatttacta caaagtcgtg ttttaaacac aaaaagaaag
    49621 agatagattg aaactttagt tgtaacggac aaatagtagt cattggagtt cagcaattca
    49681 tactttgtac taaagtttac tataatctat ctctcaaggt ttaaatgtac atatctatat
    49741 taaaatgcgt ttcatgatgt tagaagatac catacacatt taattagtta cagcataaat
    49801 caatttatac ccttaattat tacattgttt atattttaaa ttcgggggag taattttaag
    49861 taatatcttg ttgctgctaa ttctattgtt aataaattga tatttgatgt agaaattgag
    49921 tgtgaaagtt aataatagat gatttagcta gtaacataat taattcatat atagtcaaaa
    49981 agttctgtta gatactgttc ttgatgaata ttctttgatg ttaggtgtta gctattctag
    50041 atgagtttct tagatgtgga tgcctgtctt gatgaagtta tctatgatgt taatataata
    50101 cttgatgttg attcttagat gttagtgcga tttcaagatg ctgattcttt gttgttgcac
    50161 tatcttggtg acgtttctag ttgtttatag ttatcgcatc tcttgatgta aaatctaaga
    50221 tgtttatgca tttctagatg ttaattcttc gctgcttaag aattatcttg atggtaaatc
    50281 tagttgtgcc atgcattttc tcatgatgaa tctaaggtgt taattcattg atgtgtgctg
    50341 tttcttgttg cttcattatc ttgatggtga atttcgttgt ctaatgcact ttttcaaatg
    50401 attattctaa ttgttacggc aataactaga tggattttct tagatgttca cttttctaga
    50461 tgtttatact tatcttgatg ttttctaaac agaactttta aacgctttat ttttcagtag
    50521 attgtttaaa atttcttagt tgatggttat tgttgttgat ttgaataatt tgtagcgaat
    50581 attttgtaac agggctacta agaattttta taacaagaag tgatttcaat cgtactaatt
    50641 ttcagcgttt gatgacaaaa gtgtatgtcc aaacttaaat aatggcgata aaatttaagt
    50701 catgggtaca tttaatgttt tttgattcaa acttccattt tggtcaattt gcttttttta
    50761 taacatagtt gaatatcaat aaaagattag caagtaagtt caaaatggct atgtattgtt
    50821 ttttgaaata cataggtttg aaatctatat taattatgca ccaaataatt taattagact
    50881 ctatcgaaaa tttccaaatt tcgcttacta tctttctaat tttactttta tattgtgcac
    50941 aatgcataaa aacaagcgtt ttcctaggag ttttcattaa tttcttttat ttttcactat
    51001 taccttttca aaaatattca actataatag gtatactatc catgatttta aaaatttcca
    51061 tgttttacat ttaaatgata gatttcaata tatattaggc aggagagaga aatatgacat
    51121 gccaacttaa aatacatcat acattatcga caataccaag tcgtaatatt aataatatta
    51181 tggtgctatt ttcacttaca agtaaactca atattacgat taatggtgaa accaaagacg
    51241 taagtaatta tattatctta attaaccatg gtgatattta taatattaac cacggcgaaa
    51301 atataatcga attaatgata cccgtttttt attttcatca acaagatgat gatttcttta
    51361 atggttattt agatcgtcat ttattacaat caagtaatta tattaagtca ttaattgccg
    51421 atttaatcag tacaccaaca agttcttctt taatgggaaa aaatataggt caaagtatta
    51481 tagacacttt acttaaagaa gcttttataa gaatagatca tgaatattta ccaaatattg
    51541 ctttaagcaa tccagtgttt atagattgtg taaactatat tcatgacaat attgatgcgc
    51601 acttgtcttt aaaagatata gcgatgcatt gcaacatctc tgaatcatat tgttctaatc
    51661 tttttgttcg atatttgagt atgaatttta aagattattt tacaagtatt aaacttgtta
    51721 acgccatcaa tttattactt tctacaaaac attctattac aactgtttct gaattggctg
    51781 gttttaacag tcatacaaat tttgcaaatc aatttaagaa ttacttgcat tttagtccta
    51841 aacagttccg ttcactcgtt tccaagatta ctgaaccacc acaaatacac ttccaacaag
    51901 ataacgtatc acaattcact gagttaattt caacaattga tttaacagct cagttggcta
    51961 caaatacaac agatattcat atagatgatt ttaatccgaa agatcgaagt cagcgtgcca
    52021 aagtatttgt tcgattcagt aatttcaatg aactatttca atttattttc aatgaatatt
    52081 acgatattaa ctttgagcac ttaccaaaac ctgtcgtttt cattgacgat attcacgata
    52141 ttgagattag ccaaacgaat tacaacctgt taaatagatg ttttgaaaag cttttcgaaa
    52201 aaaatatagg tttagcaatc gctattaaat caacacaaca attcgaaacg atgaagcaat
    52261 taatactaac atttttacaa ggcaatcaag actataagac aagcaagaaa ttagttaaat
    52321 ttatgctcgt attttgctct aattctatga cagcagaaga aattcattta tgtcatctta
    52381 aaattaaaaa caaaaataaa gaaattaaat atagtgtgac agtcgatggc tttttagaaa
    52441 cttattcaac cgtggaacaa gtttatgatg tcatgcagcg tcttaaattc cattattact
    52501 ttattgatat tgaaaattca aaaactgcaa cacatcttat cactaaaaat caacactatc
    52561 atcaaactga cacacatttt gaacagtata agaaatttat tttagattca ggtatatcat
    52621 caacacaatt tgtatataat aacctgtctg taagcgggtt taaatatact aatgatggta
    52681 agaatccaat tcaattatct gacatagtgt atcacttaat cgcattatta cgatatggcg
    52741 gtggcattag ctatcaatta ttagatgacc attcaaatta tatttccttg tacaacaaat
    52801 atggtagccc cctaccatta atgcatttat ataaaatgtt tagacctttt gttaacgaag
    52861 acattgaaat tacaaataat tatgtattga gtcgtaaaga taataactac catttcttat
    52921 tattcaataa aattaatgat cgatatatgt cagacgtaaa acaagatttc attttccata
    52981 atgaattacc tcaagactct ttgatgatta ttaaaacatt gaatcatgaa catggttcaa
    53041 ttcaacattt gcttccaata agcgatcaac ttgtttatat agaaaaagaa attttagatg
    53101 aattagacaa aacgaattac cctaaaacgg agcttgcagt tcaagaagaa actggtcgta
    53161 catttgaact caagttaaat cacgacgagg ttaaatatat ttgctttaaa ccaagctaaa
    53221 tactaacagt cctcttgtgt ttagtttctt acgttaaagg ctatttatat cataaggaga
    53281 tgatgtagga tgagtaactc acaagcaatt caagcaattg aaaacgtgtt agcaacgtca
    53341 aaagttggtg tattatcaac tgcatataat aacaaaccta atagtagata tatggtcttt
    53401 tataatgatg gtcttacttt atatactaaa acgaatatcc attctgctaa ggtcaaagaa
    53461 attaaagata atccagcagc atatgttttg ttaggctata acgacacaac taatcgtagt
    53521 ttcgttgaga tggaagcgac catcgaaatc gttacagaac aagaagtgat tgattggcta
    53581 tgggaaacac aagacaaaag ctttttcagt tcaaaagaag acccagagtt atgtgtttta
    53641 agagtagttc cgcaatccat taagctaatg aatgataaat cattagatac acctattaaa
    53701 attgatttat aatatgtaag tttttagttt taaaattagc cagcaattga acatgttag
//
LOCUS       DAPSKH010000009        52500 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPSKH010000009 DAPSKH010000000
VERSION     DAPSKH010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 52500)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52500)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52500
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.009"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            201..596
                     /locus_tag="RPH49_000652"
     CDS             201..596
                     /locus_tag="RPH49_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl peptide receptor-like 1 inhibitory
                     protein"
                     /protein_id="HDY5123841.1"
                     /translation="MKKNITKVIIASTVIATGLLTHSNDAKAFFSYEWKGLEIAKKLA
                     DDEKKDEERADRLIKDAEKERTYTGKTVEDLYVIAKKLGKGNTIAVVRIIDGGKNGYY
                     TFDITRPLEEHRKNIPVVKNGEIDSITWY"
     gene            577..648
                     /locus_tag="RPH49_000653"
     CDS             577..648
                     /locus_tag="RPH49_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123842.1"
                     /translation="MQLLGIKKHTELNSCTPNVRKKC"
     gene            complement(956..1285)
                     /gene="ecb"
                     /locus_tag="RPH49_000654"
     CDS             complement(956..1285)
                     /gene="ecb"
                     /locus_tag="RPH49_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement convertase inhibitor Ecb"
                     /protein_id="HDY5123843.1"
                     /translation="MKKNFIGKSILSIAAISLTVSTFAGESHAQTKNAETVKKYNEYQ
                     TNFKKQVNKKVVDAQKAVNLFKRTRTVATHRKAQRAVNLIHFQHSYEKKKLQRQIDLV
                     LKYNTLK"
     gene            complement(1479..1646)
                     /locus_tag="RPH49_000655"
     CDS             complement(1479..1646)
                     /locus_tag="RPH49_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123844.1"
                     /translation="MKRIVLLRNVIVDGPIWLNHVDYLVKSVLLKSIKLRFQEVRKIE
                     NLVKSMNRIHI"
     gene            complement(1775..2278)
                     /locus_tag="RPH49_000656"
     CDS             complement(1775..2278)
                     /locus_tag="RPH49_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDY5123845.1"
                     /translation="MSKWIIVSDNHTESGVLYQIYEMHPDADVYLHLGDSEFAYDDTE
                     LSLFNRVKGNCDFYPEFENEAVAKCNDVYAFYTHGHLYQVNRTRHLLAEQARELGCVF
                     AFYGHTHVAKYEYINGVHVINPGSISQSRSSMEETYAEVLIDDQTLHGTVNFKNRHHE
                     TISHTTF"
     gene            complement(2271..2858)
                     /locus_tag="RPH49_000657"
     CDS             complement(2271..2858)
                     /locus_tag="RPH49_000657"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HDY5123846.1"
                     /translation="MKEIVIASNNQGKINDFKVIFPDYHVIGISELIPDFDVEETGST
                     FEENAILKSEAAAKALNKTVIADDSGLEVFALNGEPGIYSARYAGENKSDEANIEKLL
                     NKLGNTTDRRAQFVCVISMSGPDMETKVFKGTVSGEIADGKYGDNGFGYDPIFYVPKL
                     DKTMAQLSKEEKGQISHRRNAINLLEAYLAGDQHV"
     gene            complement(2870..3670)
                     /gene="racE"
                     /locus_tag="RPH49_000658"
     CDS             complement(2870..3670)
                     /gene="racE"
                     /locus_tag="RPH49_000658"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDY5123847.1"
                     /translation="MNKPIGVIDSGVGGLTVAKEIMRQLPNETIYYLGDIGRCPYGPR
                     PGEQVKQYTVEIARKLMEFDIKMLVIACNTATAVALEYLQKTLSIPVIGVIEPGARTA
                     IMTTRNQNVLVLGTEGTIKSEAYRTHIKRINPHVEVHGVACPGFVPLVEQMRYSDPTI
                     TSIVIHQTLKRWRNSESDTVILGCTHYPLLYKPIYDYFGGKKTVISSGLETAREVSAL
                     LTFSNEHASYTEHPDHRFFATGDPTHITNIIKEWLNLSVNVERISVND"
     gene            complement(3906..4721)
                     /gene="sdhB"
                     /locus_tag="RPH49_000659"
     CDS             complement(3906..4721)
                     /gene="sdhB"
                     /locus_tag="RPH49_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit"
                     /protein_id="HDY5123848.1"
                     /translation="MTDQPVKDTPQHETQSKPKQKTVKLIIKRQDTSDSKPYEETFEI
                     PYRENLNVIACLMEIRRNPVNIKGEKTTPVVWDMNCLEEVCGACSMVINGRARQSCSA
                     IVDQLEQPIRLEPMNTFPVIRDLQVDRSRMFDNLKRMKAWIPIDGTYDLGPGPRMPEK
                     KRQTAYELSKCMTCGVCLEVCPNVTENNKFVGAQAISQVRLFNLHPTGSMTKDERLNA
                     LMGTGGLQQCGNSQNCVNACPKGIPLTTSIAAMNRETTFHMFKSFFGSDHEVE"
     gene            complement(4721..6487)
                     /gene="sdhA"
                     /locus_tag="RPH49_000660"
     CDS             complement(4721..6487)
                     /gene="sdhA"
                     /locus_tag="RPH49_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDY5123849.1"
                     /translation="MAEKHLIVVGGGLAGLMSTIKAAEKGAHVDLFSVVPVKRSHSVC
                     AQGGINGAVNTKGEGDSPWIHFDDTVYGGDFLANQPPVKAMTEAAPKIIHLLDRMGVM
                     FNRTNEGLLDFRRFGGTLHHRTAYAGATTGQQLLYALDEQVRAYEVDGLVTKYEGWEF
                     LGIVKGDDDSARGIVAQNMTTAEIETFGSDAVIMATGGPGIIFGKTTNSMINTGSAAS
                     IVYQQGAIYANGEFIQIHPTAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKY
                     PDYGNLVPRDIATREIFDVCINQKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEK
                     FTGDDPRKVPMKIFPAVHYSMGGLYVDYDQMTNIKGLFAAGECDFSQHGGNRLGANSL
                     LSAIYGGTVAGPNAIDYIANIDRSYTDMDESIFEKRKAEEQERFEKLMAMRGTENAYK
                     LHRELGEIMTANVTVVRENEKLLETDKKIVELMKRYENIDMEDTQTWSNQAVFFTRQL
                     WNMLVLARVITIGAYNRNESRGAHYKPEFPERNDEEWLKTTMASFQGAFEKPQFTYDD
                     VDVSLIPPRKRDYTSKSKGGKK"
     gene            complement(6539..7153)
                     /locus_tag="RPH49_000661"
     CDS             complement(6539..7153)
                     /locus_tag="RPH49_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b558 subunit"
                     /protein_id="HDY5123850.1"
                     /translation="MAQSKNEFYLRRIHSLLGIIPIGAFLVVHLLVNHQATQGAEAFN
                     KASNFMESLPFLIIVEFLFIYIPLLYHGLFGIHIAFTAKENVGHYSIFRNWMFFFQRV
                     SGILTFIFIGIHLWQTRLQKAFYGKEVNYDLMHETLQHPGWAIFYIICIIAVVFHFAN
                     GLWSFLVTWGGLQSPKSQRVFTWVSLIVFLVISYIGVTAIIAFM"
     gene            complement(7477..9258)
                     /gene="uvrC"
                     /locus_tag="RPH49_000662"
     CDS             complement(7477..9258)
                     /gene="uvrC"
                     /locus_tag="RPH49_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499646.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDY5123851.1"
                     /translation="MEDYKQRIKNKLNVVPMEPGCYLMKDRNDQVIYVGKAKKLRNRL
                     RSYFTGAHDAKTTRLVGEIRHFEFIVTSSETESLLLELNLIKQYQPRYNILLKDDKSY
                     PFIKITKEKYPRLLVTRTVKQGTGKYFGPYPNAYSAQETKKLLDRIYPYRKCDKMPDK
                     LCLYYHIGQCLGPCVYDVDLSKYAQMTKEITDFLNGEDKTILKSLEERMLTASESLDF
                     ERAKEYRDLIQHIQNLTNKQKIMSSDKTIRDVFGYSVDKGWMCIQVFFIRQGNMIKRD
                     TTMIPLQQTEEEEFYTFIGQFYSLNQHILPKEVHVPRNLDKEMIQSVVDTKIVQPARG
                     PKKDMVDLAAHNAKVSLNNKFELISRDESRTIKAIEELGTQMGIQTPIRIEAFDNSNI
                     QGVDPVSAMVTFVDGKPDKKNYRKYKIKTVKGPDDYKSMREVVRRRYSRVLNEGLPLP
                     DLIIVDGGKGHMNGVIDVLQNELGLDIPVAGLQKNDKHQTSELLYGASAEIVPLKKNS
                     QAFYLLHRIQDEVHRFAITFHRQTRQKTGLKSILDDIEGIGSKRKTLLLRSFGSIKKM
                     KEATLEDFKNIGIPENVAKNLHEQLHK"
     gene            9424..9519
                     /locus_tag="RPH49_000663"
     CDS             9424..9519
                     /locus_tag="RPH49_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123852.1"
                     /translation="MLDYHLTFIDLLIPPFSSRKQYDDLSFNFLY"
     gene            complement(9582..9896)
                     /gene="trxA"
                     /locus_tag="RPH49_000664"
     CDS             complement(9582..9896)
                     /gene="trxA"
                     /locus_tag="RPH49_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDY5123853.1"
                     /translation="MAIVKVTDADFDSKVESGVQLVDFWATWCGPCKMIAPVLEELAA
                     DYEGKADILKLDVDENPSTAAKYEVMSIPTLIVFKDGQPVDKVVGFQPKENLAEVLDK
                     HL"
     gene            complement(10069..12417)
                     /locus_tag="RPH49_000665"
     CDS             complement(10069..12417)
                     /locus_tag="RPH49_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDY5123854.1"
                     /translation="MRQKTLDVLEFEKIKSLVANETISDLGLEKVNQMMPATNFETVV
                     FQMEETDEIAQIYNKHRLPSLSGLSKVSAFIHRADIGGVLNVSELNLIKRLIQVQNQF
                     KTFYNQLVEEDEGVKYPILDDKMNQLPVLTDLFQQINETCDTYDLYDNASYELQGIRS
                     KISSTNQRIRQNLDRIVKSQANQKKLSDAIVTVRNERNVIPVKAEYRQDFNGIVHDQS
                     ASGQTLYIEPSSVVEMNNQISRLRHDEAIEKERILTQLTGYVAADKDALLVAEQVMGQ
                     LDFLIAKARYSRSIKGTKPIFKEERTVYLPKAYHPLLNRETVVANTIEFMEDIETVII
                     TGPNTGGKTVTLKTLGLIIVMAQSGLLIPTLDGSQLSIFKNVYCDIGDEQSIEQSLST
                     FSSHMTNIVEILKHADKHSLVLFDELGAGTDPSEGAALAMSILDHVRKIGSLVMATTH
                     YPELKAYSYNREGVMNASVEFDVDTLSPTYKLLMGVPGRSNAFDISKKLGLSLNIINK
                     AKTMIGTDEKEINEMIESLERNYKRVETQRLELDRLVKEAEQVHDDLSKQYQQFQNYE
                     KSLIEEAKEKANQKIKAATKEADDIIKDLRQLREQKGADVKEHELIDKKKRLDDHYEA
                     KSIKQNVQKQKYDKIVAGDEVKVLSYGQKGEVLEIVNDEEAIVQMGIIKMKLPIEDLE
                     KKQKEKVKPTKMVTRQNRQTIKTELDLRGYRYEDALIELDQYLDQAVLSNYEQVYIIH
                     GKGTGALQKGVQQHLKKHKSVSDFRGGMPSEGGFGVTVATLK"
     gene            complement(12427..14139)
                     /gene="polX"
                     /locus_tag="RPH49_000666"
     CDS             complement(12427..14139)
                     /gene="polX"
                     /locus_tag="RPH49_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase/3'-5' exonuclease PolX"
                     /protein_id="HDY5123855.1"
                     /translation="MTKKDVIKLLEQIATYMELKGENTFKISAYRKAAQSLELDERPL
                     DEISDVTDLKGIGKGVAEVINDYRETGESQYLQQLQEEVPEGLIPLLKIQGLGSKKIA
                     KLYKELNIVDKASLQVACENGKVSELSGFAKKTEQNILEAVKQLGAKKDRYPIDQMRR
                     LNQEIIDYIDTLNYIDQYSSAGSFRRFKEMSKDLDFIISTDNPKAVQQQLLNIPNKVK
                     EVAVGNTKVSLELAYDDETIGVDFRLIEPSAFYHTLQHFTGSKEHNIRIRQLAKARDE
                     KVSEYGIEQADGTLIQYDSEAKIYEHFNVNFIPPAMREDGSEFDKDLSNIITLDDING
                     DIHMHTTYSDGAFSIRDMVEANIAKGYKFMVITDHSQSLRVANGLQVERLLRQNEEIK
                     ALDKEYSEIDIYSGTEMDILTDGSLDYDDEILAQLDYVIGAIHQSFNQSEEQIMERLA
                     NACRNPYVRHIAHPTGRIIGRRDGYKPNIEQLMALAEETNTVLEINANPHRLDLNADI
                     VRKYPNVKLTINTDAHHTNHLDFMNYGVATAQKGFVTKDRVINALSREAFKDFIENNI
                     KLKK"
     gene            complement(14212..14733)
                     /locus_tag="RPH49_000667"
     CDS             complement(14212..14733)
                     /locus_tag="RPH49_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDY5123856.1"
                     /translation="MVIDFIIIIFFVYFVIVGFRRGFWLSMIHLSATIVSLWIASQFY
                     KSIVERLIVFIPYPKTTAFNTTFAFHFNHLQNRFEAIVAFLMITLFCKFILYLIIVTF
                     DKIIAYQNIHIFSRAMGMIVGVFMTIIVLHFTLYLLALYPNEALQHQLKISIVSHSLI
                     FHIPYLSAFTINL"
     gene            complement(14734..15000)
                     /gene="zapA"
                     /locus_tag="RPH49_000668"
     CDS             complement(14734..15000)
                     /gene="zapA"
                     /locus_tag="RPH49_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDY5123857.1"
                     /translation="MAQFKNKVNVSINDQLFTIVGEDNPEHIRYVAHLVDDKIKELGY
                     KAAGLDTSRKAILTAVNIMHEKVLLEEENRRLKQQIHKLQQREQ"
     gene            15375..16313
                     /locus_tag="RPH49_000669"
     CDS             15375..16313
                     /locus_tag="RPH49_000669"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDY5123858.1"
                     /translation="MANIVFKLSDKDITTLMSRISFDTENLPQGMKARAKYQNTTVNI
                     YQSGKVMFQGNHAEAVSQELLPQHSQLNTNKTKKKNMANSFLEQSLMYDQFNCIGSDE
                     AGSGDYFGPLTVCAAFVTKEHVLILKTLGVDDSKKLTDTKIVELAEQLVTFIPHSLLT
                     LHNEKYNIQQAKGWTQVKMKAVLHNEAIKNVLEKIDSSQLDYIVIDQFAKREVYSHYA
                     LSDIPLPKKTKFETKGESKSLAIAVASIISRYAFVTYMDQISKNINMTIPKGAGAKVD
                     VIAAKIIKKYGLSRLDTISKKHFKNREKAQKILKPL"
     gene            complement(16748..19150)
                     /locus_tag="RPH49_000670"
     CDS             complement(16748..19150)
                     /locus_tag="RPH49_000670"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDY5123859.1"
                     /translation="MLISNEWLKEYVTIDDSVSNLAERITRTGIEVDDLIDYTKDIKN
                     LVVGFVKSKEKHPDADKLNVCQVDIGEDEPVQIVCGAPNVDAGQYVIVAKVGGRLPGG
                     IKIKRAKLRGERSEGMICSLQEIGISSNYVPKSFESGIYVFSESQVPGTDALQALYLD
                     DQVMEFDLTPNRADALSMIGTAYEVAALYNTKMTKPDTTSNELELSANDELTVTIENE
                     DKVPYYSARVVHDVTIEPSPIWMQARLIKAGIRPINNVVDISNYVLLEYGQPLHMFDQ
                     DAIGSQQIVVRQANEGEKMTTLDDTERELLTSDIVITNGQTPIALAGVMGGDFSEVKE
                     HTSNIVIEGAIFDPVSIRHTSRRLNLRSESSSRFEKGIATEFVDEAVDRACYLLQTYA
                     NGKVLKDRVSSGELGAFITPIDITADKINRTIGFDLSQNDIVTIFNQLGFDTEINDDV
                     ITVQVPSRRKDITIKEDLIEEVARIYGYDDIPSTLPVFEKVTSGQLTDRQYKTRMVKE
                     VLEGAGLDQAITYSLVSKEDATAFAMQQRQTIDLLMPMSEAHASLRQSLLPHLIEAAS
                     YNVARKNKDVKLFEIGNVFFANGEGELPDQVEYLSGILTGDYVVNQWQGKKETVDFYL
                     AKGVVDRVSEKLNLEFSYRRADIDGLHPGRTAEILLENKVVGFIGELHPTLAADNDLK
                     RTYVFELNFDALMAVSVGYINYQPIPRFPGMSRDIALEVDQNIPAADLLSTIHAHGGN
                     ILKDTLVFDVYQGEHLEKGKKSIAIRLNYLDTEETLTDERVSKVQAEIEAALIEQGAV
                     IR"
     gene            complement(19150..20208)
                     /gene="pheS"
                     /locus_tag="RPH49_000671"
     CDS             complement(19150..20208)
                     /gene="pheS"
                     /locus_tag="RPH49_000671"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDY5123860.1"
                     /translation="MSEQQTMSELKQQALVDINEANDERALQEVKVKYLGKKGSVSGL
                     MKLMKDLPNEEKPAFGQKVNELRQTIQNELDERQQMLVKEKLNKQLAEETIDVSLPGR
                     HIEIGSKHPLTRTIEEIEDLFLGLGYEIVNGYEVEQDHYNFEMLNLPKSHPARDMQDS
                     FYITDEILLRTHTSPVQARTMESRHGQGPVKIICPGKVYRRDSDDATHSHQFTQIEGL
                     VVDKNVKMSDLKGTLELLAKKLFGADREIRLRPSYFPFTEPSVEVDVSCFKCKGKGCN
                     VCKHTGWIEILGAGMVHPNVLEMAGFDSSEYSGFAFGMGPDRIAMLKYGIEDIRHFYT
                     NDVRFLDQFKAVEDRGDM"
     gene            complement(20589..21329)
                     /locus_tag="RPH49_000672"
     CDS             complement(20589..21329)
                     /locus_tag="RPH49_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDY5123861.1"
                     /translation="MEQITSAQNNRIKQANKLKKKRERDKTGLALIEGVHLIEEAYQS
                     GIVITQLFAIEPARLDQQIIAYAQEVFEINMKVAESLSGTVTPQGFFAIIEKPQYDIS
                     KAQQVLLIDRVQDPGNLGTLIRTADAAGMDAVIMEKGTTDPYQDKVLRASQGSVFHLP
                     VMTQDLDTFITQFNGPVYGTALENAVAYKEVTSSDSFALLLGNEGEGVNPELLAHTTQ
                     NLIIPIYGKAESLNVAIAGSILLYHLKG"
     gene            complement(21569..21676)
                     /locus_tag="RPH49_000673"
     CDS             complement(21569..21676)
                     /locus_tag="RPH49_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123862.1"
                     /translation="MVLLAFVTTIHDTDDGRFFNEHKHANNKLLKRSLI"
     gene            complement(21713..22036)
                     /gene="isdG"
                     /locus_tag="RPH49_000674"
     CDS             complement(21713..22036)
                     /gene="isdG"
                     /locus_tag="RPH49_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylobilin-forming heme oxygenase IsdG"
                     /protein_id="HDY5123863.1"
                     /translation="MKFMAENRLTLTKGTAKDIIERFYTRHGIETLEGFDGMFVTQTL
                     EQEDFDEVKILTVWKSKQAFTDWLKSDVFKAAHKHVRSKNEDESSPIINNKVITYDIG
                     YSYMK"
     gene            complement(22055..22789)
                     /gene="srtB"
                     /locus_tag="RPH49_000675"
     CDS             complement(22055..22789)
                     /gene="srtB"
                     /locus_tag="RPH49_000675"
                     /EC_number="3.4.22.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class B sortase"
                     /protein_id="HDY5123864.1"
                     /translation="MRMKRFLTIVQILLVVIIIIFGYKIVQTYIEDKQERANYEKLQQ
                     KFQMLMSKHQAHVRPQFESLEKINKDIVGWIKLSGTSLNYPVLQGKTNHDYLNLDFER
                     EHRRKGSIFMDFRNELKNLNHNTILYGHHVGDNTMFDVLEDYLKQSFYEKHKIIEFDN
                     KYGKYQLQVFSAYKTTTKDNYIRTDFENDQDYQQFLDETKRKSVINSDVNVTVKDKII
                     TLSTCEDAYSETTKRIVVVAKIIKVS"
     gene            complement(22851..23816)
                     /gene="isdF"
                     /locus_tag="RPH49_000676"
     CDS             complement(22851..23816)
                     /gene="isdF"
                     /locus_tag="RPH49_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin ABC transporter permease protein IsdF"
                     /protein_id="HDY5123865.1"
                     /translation="MIKNKKKLLFLCLLVILIATAYISFVTGTIKLSFNDLFTKFTTG
                     SNEAVDSIIDLRLPRILIALMVGAMLAVSGALLQAALQNPLAEANIIGVSSGALIMRA
                     LCMLFIPQLYFYLPLLSFIGGLIPFLIIILLHSKFRFNAVSMILVGVALFVLLNGVLE
                     ILTQNPLMKIPQGLTMKIWSDVYILAVSALLGLILTLLLSTKLNLLNLDDVQARSIGF
                     NIDRYRWLTGLLAVFLASATVAIVGQLAFLGIIVPHVVRKLVGGNYRVLIPFSTVIGA
                     WLLLVADLLGRVIQPPLEIPANAILMIVGGPMLIYLICQSQRNRI"
     gene            complement(23829..24707)
                     /gene="isdE"
                     /locus_tag="RPH49_000677"
     CDS             complement(23829..24707)
                     /gene="isdE"
                     /locus_tag="RPH49_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     IsdE"
                     /protein_id="HDY5123866.1"
                     /translation="MRIIKYLTILVISVVILTSCQSSSSQESTKSGEFRIVPTTVALT
                     MTLDKLDLPIVGKPTSYKTLPNRYKDVPEIGQPMEPNVEAVKKLKPTHVLSVSTIKDE
                     MQPFYKQLNMKGYFYDFDSLKGMQKSITQLGDQFDRKAQAKELNDHLNSVKQKIENKA
                     AKQKKHPKVLILMGVPGSYLVATDKSYIGDLVKIAGGENVIKVKDRQYISSNTENLLN
                     INPDIILRLPHGMPEEVKKMFQKEFKQNDIWKHFKAVKNNHVYDLEEVPFGITANVDA
                     DKAMTQLYDLFYKDKK"
     gene            complement(24704..25780)
                     /gene="isdD"
                     /locus_tag="RPH49_000678"
     CDS             complement(24704..25780)
                     /gene="isdD"
                     /locus_tag="RPH49_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-regulated surface determinant protein IsdD"
                     /protein_id="HDY5123867.1"
                     /translation="MRNVKQIATKSIIAIISLGILTYTTMIGSVLADEIKYPSAKFNQ
                     PEAKDKTELTTSIFDEKIKENKALELVIFNQENKNVTEEQQLVDEKAQLISDMTGKIY
                     LQVKLKGQIDKEQLVFQNDKNEEFPFVIKDEKDDTIVRILIEQHMDKINMHVKTLAEK
                     KNLDNKEMVYSIHFKEKKVQHDDAKEVPSKHQSQENNQDQLKKDIDDKKDSQKSDIKE
                     RRTSLFTEKGLNDIPVQKDKVQQDSNKKIENERPKASGTLKVENNPSTVKKVENNHKE
                     QPKHKDEKSKKEKKKVVEKEKALPAFNRDDDSKNSSQLSSDIKELDEPNHKKQYMLFA
                     AGIVLATILLISAHLYSRKRGNQV"
     gene            complement(25780..26463)
                     /gene="isdC"
                     /locus_tag="RPH49_000679"
     CDS             complement(25780..26463)
                     /gene="isdC"
                     /locus_tag="RPH49_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme uptake protein IsdC"
                     /protein_id="HDY5123868.1"
                     /translation="MKNILKVFNTTILALIIIIATFSNSANAADSGTLNYEVYKYNTN
                     DTSIANDYFNKPAKYIKKNGKLYVQITVNHSHWITGMSIEGHKENIISKNTAKDERTS
                     EFEVSKLNGKIDGKIDVYIDEKVNGKPFKYDHHYNITYKFNGPTDVAGANAPGKDDKN
                     SASGSDKGSDGTTTGQSESNSSNKDKVENPQTNAGTPAYIYAIPVASLALLIAITLFV
                     RKKSKGNVE"
     gene            26672..27724
                     /gene="isdA"
                     /locus_tag="RPH49_000680"
     CDS             26672..27724
                     /gene="isdA"
                     /locus_tag="RPH49_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored heme-scavenging protein IsdA"
                     /protein_id="HDY5123869.1"
                     /translation="MTKHYLNSKYQSEQRSSAMKKITMGTASIILGSLVYIGADSQQV
                     NAATEATNATNNQSTQVSQATSQPINFQVQKDGSSEKSHMDDYMQHPGKVIKQNNKYY
                     FQTVLNNASFWKEYKFYNANNQELATTVVNDNKKADTRTINVAVEPGYKSLTTKVHIV
                     VPQINYNHRYTTHLEFEKAIPTLADAAKPNNVKPVQPKPAQPKTPTEQTKPVQPKVEK
                     VKPTVTTTSKVEDNHSTKVVSTDTTKDQSQTQSARTVKTTQTAQEQNKVQTPVKDVAT
                     AKSESNSQAVSDNKSQQTNKVTKQNETPKQASKAKELPKTGLTSVDNFISTVAFATLA
                     LLGSLSLLLFKRKESK"
     gene            27927..29861
                     /gene="isdB"
                     /locus_tag="RPH49_000681"
     CDS             27927..29861
                     /gene="isdB"
                     /locus_tag="RPH49_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme uptake protein IsdB"
                     /protein_id="HDY5123870.1"
                     /translation="MNKQQKEFKSFYSIRKSSLGVASVAISTLLLLMSNGEAQAAEET
                     GGTNTEAQPKTEALASPTTTTEKAPETKPVANAVSVSNKEVEAPTSETKEAKEVKEVK
                     APKETKAVKPAAKADNNTYPILNQELREAIKNPAIKDKDHSAPNSRPIDFEMKKENGE
                     QQFYHYASSVKPARVIFTDSKPEIELGLQSGQFWRKFEVYEGDKKLPIKLVSYDTVKD
                     YAYIRFSVSNGTKAVKIVSSTHFNNKEEKYDYTLMEFAQPIYNSADKFKTEEDYKAEK
                     LLAPYKKAKTLERQVYELNKIQDKLPEKLKAEYKKKLEDTKKALDEQVKSAITEFQNV
                     QPTNEKMTDLQDTKYVVYESVENNESMMDTFVKHPIKTGMLNGKKYMVMETTNDDYWK
                     DFMVEGQRVRTISKDAINNTRTIIFPYVEGKTLYDAIVKVHVKTIDYDGQYHVRIVDK
                     EAFTKANTDKSNKKEQQDNSAKKEATPATPSKPTPSPVEKESQKQDSQKDDNKQLPSV
                     EKENDASSESGKDKTPATKPAKGEVESSSTTPTKVVSTTQNVAKPTTASSKTTKDVVQ
                     TSAGSSEAKDSAPLQKANIKNTNDGHTQSQNNKNTQENKAKSLPQTGEESNKDMTLPL
                     MALLALSSIVAFVLPRKRKN"
     gene            complement(30015..30188)
                     /gene="rpmF"
                     /locus_tag="RPH49_000682"
     CDS             complement(30015..30188)
                     /gene="rpmF"
                     /locus_tag="RPH49_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019469283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDY5123871.1"
                     /translation="MAVPKRRTSKTRKNKRRTHFKISVPGMTECPNCGEYKLSHRVCK
                     NCGSYNGEEVAAK"
     gene            complement(30268..30825)
                     /locus_tag="RPH49_000683"
     CDS             complement(30268..30825)
                     /locus_tag="RPH49_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDY5123872.1"
                     /translation="MKWSITQLRKYQGKPFEFDQTVSFDNLKESLDLIDLSPITIQGQ
                     LTIKSTEVVADIHITGTYTMPCARTLVPVKVPLDVTTTEVFDLEGYNQYNDDQDDVDE
                     HYHIIKDGMVNLQDIVEDIVIIEKPMRAYSEQSDQMLTVGNGWEVIDEDQLDELAKQQ
                     EQDDSESRQVDPRLQKLQQLYDKEQ"
     gene            30952..32091
                     /locus_tag="RPH49_000684"
     CDS             30952..32091
                     /locus_tag="RPH49_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDY5123873.1"
                     /translation="MKSVGLITEYNPFHNGHQYHINQSKKLTNADVTIAIMSGNFVMR
                     GEPAIYNKFTRAKMALSTADLVIELPATASLSSGDHFAELAVKVADYMSVDTIAFGSE
                     NNDIKTLKQLAHSINEIEQSESFSQKVKEGKSYPRIISELLEHHEALESPNNILGISY
                     LKAIAKHAKNINAISIKRENAQHHDSLIQHHQFASGTSIRTSIISQDDHWHHVVPKDI
                     QHLYVTPHITLNQIFPYLKYQIIAMTTESLKNIYTVTEGFENRLKSNIYEATDFHHFI
                     KLLKTKRYTYTHIQRLLMNVLLNIKPTDITRNIHAVKVLAMNDRGRQYLKHLKTAFPE
                     RQYITNINKSNAHYFTNEIKATHIYNAISGQQQTDFNTPVIQQYR"
     gene            complement(32153..32635)
                     /gene="coaD"
                     /locus_tag="RPH49_000685"
     CDS             complement(32153..32635)
                     /gene="coaD"
                     /locus_tag="RPH49_000685"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDY5123874.1"
                     /translation="MEHTIAVIPGSFDPITYGHLDIIERSTDRFDEIHVCVLKNSKKE
                     GTFSLEERMDLIEQSVKHLPNVKVHQFSGLLVDYCEQVGAKTIIRGLRAVSDFEYELR
                     LTSMNKKLNNEIETLYMMSSTNYSFISSSIVKEVAAYRADISEFVPPYVEKALKKKFK
                     "
     gene            complement(32637..33179)
                     /gene="rsmD"
                     /locus_tag="RPH49_000686"
     CDS             complement(32637..33179)
                     /gene="rsmD"
                     /locus_tag="RPH49_000686"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002470236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDY5123875.1"
                     /translation="MRVIAGKHKSKALESMEGRNTRPTMDKVKEGIFNSLYDVSGIGL
                     DLFAGSGALGIEALSRGMDKVIFVDQNFKAVKVIKSNLANLDLEAQSEVYKNNADRAL
                     KALSKRDIQFDVIFLDPPYNKGLIDKALKLISEFNLLKENGIIVCEFSNHEEIDYQPF
                     NMIKRYHYGLTDTLLLEKGE"
     gene            33249..33638
                     /locus_tag="RPH49_000687"
     CDS             33249..33638
                     /locus_tag="RPH49_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123876.1"
                     /translation="MKQTFITLGEGLTDLFEFMTMIEYNHQRIDKIIYFHSPQAENKK
                     SSVAIIMNPTTGNHFQAFYIMINAIKYPYPDSNKKFQMINDCAEKFDIPILGIDVQPP
                     QAFHDLSLYYNYLISVLRLQKWIPELQ"
     gene            complement(33641..33895)
                     /locus_tag="RPH49_000688"
     CDS             complement(33641..33895)
                     /locus_tag="RPH49_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDY5123877.1"
                     /translation="MNLIPRTSIVVYLKHMKHERQIRKYGHIVHSNRDRKFVIMYVNE
                     QDVDQIVHKLMQLKYVRHIDGSPYKYLKKTYEKEKHEIYN"
     gene            34134..35060
                     /locus_tag="RPH49_000689"
     CDS             34134..35060
                     /locus_tag="RPH49_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDY5123878.1"
                     /translation="MKKVNRNILNAVLVGAGFVSSLLMINKNKVITKKQTIPAFFKGN
                     APYIFAHRGGMALRPEQTQLAFDYAKQLGVDGFETDVRLTKDQQLIVFHDATVDRTTN
                     GSGKVSAHTLAELKKLDAAYHFKDINGQTPYRGHAHTAILTFDELLKQYPDMYINVDL
                     KDAPESYEGSIAPQIMFDTIAENQAFDRVLVTSFYKEQIVRFNKIAQGSVAIGASQQE
                     VTEAFLKYHLLGGRYYQPLAQTFQMPTHFKGIDLTSSRFIKWLNDMNVIPGYYGVNSI
                     DLMNDLYQKGAHMIVTDRPDLAQQFKQTIPKK"
     gene            complement(35123..35557)
                     /locus_tag="RPH49_000690"
     CDS             complement(35123..35557)
                     /locus_tag="RPH49_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDY5123879.1"
                     /translation="MINEASLAILDDIDELADMIVASDIYASFEQAKQALENNDEAHL
                     LYQSFLKSKEKYDEVMRFGKYHPDYKKVMLETRQRKRAYEMLDVVMHYKAREMALQHL
                     IDEVVTKIAYAVSEHVKIETGNPFFQTSHSGCTTGGSCNCSL"
     gene            complement(35573..36610)
                     /locus_tag="RPH49_000691"
     CDS             complement(35573..36610)
                     /locus_tag="RPH49_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499615.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HDY5123880.1"
                     /translation="MKKLIIRVVGVLFLIGFLIYLFYSPRLKFDVLENPNKGNKVNRS
                     EQVNKSNNHAENPKPKEGVGTWVGKNIKVLTSKFGQADRVYPFRDGYKNYVFKDKNSY
                     YIVSTKREEIVSVYATGEKVNVSPLKIGQHSAEIFNHTSINPEPSFKVDGKKYEFELS
                     DEDLKTQTLIKYGDIYAQVYSDQQSKKVLSVRFLTKEMLADIEPYQLNSNSTSEEHNK
                     RPVEQNPNQLISLYEVTNEMRKLKGLKPLKINSDLAHIASNNLYEATSNGSDSVEFTE
                     DALRGQLDKNHVTYKTTAQNVGYAFNDVPTLIHSWMNSDIHRSRLLNSKYDEMGGDVM
                     RDYYSLIFLEK"
     gene            complement(36937..37398)
                     /locus_tag="RPH49_000692"
     CDS             complement(36937..37398)
                     /locus_tag="RPH49_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF420 domain-containing protein"
                     /protein_id="HDY5123881.1"
                     /translation="MGVPILPTISTTCIVISAILIAIGWRLIWKREINKHKNVMLAAA
                     VFALTFFLIYASRTIFIGNTAFGGPASIKKYYTIFLFFHINLATIGGILGLVQIITAF
                     KDKYNVHRKFGPFASVIWFCTAITGVAVYLLLYVLYPGGETTSLIKATFGH"
     gene            complement(37423..38334)
                     /locus_tag="RPH49_000693"
     CDS             complement(37423..38334)
                     /locus_tag="RPH49_000693"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDY5123882.1"
                     /translation="MSKEHTLSQNISRVNFKELQQIIKMGLVQGNLIPAFAGAWLAVV
                     MTNHSFLSSIPQILLMLLGSTLIMGGACALNNYYDQDIDRIMPSKQNRPTVNNRITDQ
                     NLLLLSFGMMLVGEICLFLLNIPSGVLGLMGIVGYVSYYSIWSKRHTTWNTVIGSFPG
                     AVPPLIGWVAIEGQISLTAIALFLVVFCWQPIHFYALAIKRKDEYALANIPMLPSVKG
                     FKRTRVSMFIWLIILLPVPLLLINLGVVFVVLATLLNLGWIALGLTTFKKNSDQTKWA
                     TQMFIYSLNYLVIFFVLAVIVSLLTLI"
     gene            38773..39684
                     /locus_tag="RPH49_000694"
     CDS             38773..39684
                     /locus_tag="RPH49_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme A synthase"
                     /protein_id="HDY5123883.1"
                     /translation="MFGKKNLKWLGVVATLMMTFVQLGGALVTKTGSADGCGSSWPLC
                     HGALIPEFFPIDTIIELSHRAVSALSLLMVLWLVITAWKHIGYIKEIKPLSIISVGFL
                     LLQALIGAAAVIWQQNDYVLALHFGISLISFSSVFLITLIIFSIDQKYEADELYIKKP
                     LRRLTWLMAIIIYCGVYTGALVRHADASLAYGGWPLPFHDLVPHSEQDWVQLTHRIMA
                     FIVFTIIMITYIHAVKNYPNNRTVHYGYTAAFILVILQVITGALSIMTNVNLIIALFH
                     ALFITYLFGMTTYFIMLMLRSVRSDKQ"
     gene            complement(39824..43276)
                     /locus_tag="RPH49_000695"
     CDS             complement(39824..43276)
                     /locus_tag="RPH49_000695"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDY5123884.1"
                     /translation="MKQIKKLLVANRGEIAIRIFRAAAELDISTVAIYSNEDKSSLHR
                     YKADESYLVGSDLGPAESYLNIERIIDVAKQANVDAIHPGYGFLSENEQFARRCAEEG
                     IKFIGPHLEHLDMFGDKVKARTTAIKADLPVIPGTDGPIKSYELAKEFAEEAGFPLMI
                     KATSGGGGKGMRIVREESELEDAFHRAKSEAEKSFGNSEVYIERYIDNPKHIEVQVIG
                     DEHGNIVHLFERDCSVQRRHQKVVEVAPSVGLSPTLRQRICDAAIQLMENIKYVNAGT
                     VEFLVSGDEFFFIEVNPRVQVEHTITEMVTGIDIVKTQILVAAGADLFGEEINMPQQK
                     DITTLGYAIQCRITTEDPLNDFMPDTGTIIAYRSSGGFGVRLDAGDGFQGAEISPYYD
                     SLLVKLSTHAISFKQAEEKMVRSLREMRIRGVKTNIPFLINVMKNKKFTSGDYTTKFI
                     EETPELFDIQPSLDRGTKTLEYIGNVTINGFPNVEKRPKPDYELASIPTVSSSKIASF
                     SGTKQLLDEVGPKGVAEWVKKQDDVLLTDTTFRDAHQSLLATRVRTKDMINIASKTAD
                     VFKDGFSLEMWGGATFDVAYNFLKENPWERLERLRKAIPNVLFQMLLRASNAVGYKNY
                     PDNVIHKFVQESAKAGIDVFRIFDSLNWVDQMKVANEAVQEAGKISEGTICYTGDILN
                     PERSNIYTLEYYVKLAKELEREGFHILAIKDMAGLLKPKAAYELIGELKSAVDLPIHL
                     HTHDTSGNGLLTYKQAIDAGVDIIDTAVASMSGLTSQPSANSLYYALNGFPRHLRTDI
                     EGMESLSHYWSTVRTYYSDFESDIKSPNTEIYQHEMPGGQYSNLSQQAKSLGLGERFD
                     EVKDMYRRVNFLFGDIVKVTPSSKVVGDMALYMVQNDLDEQSVITDGYKLDFPESVVS
                     FFKGEIGQPVNGFNKDLQAVILKGQEALTARPGEYLEPVDFEKVRELLEEEQQGPVTE
                     QDIISYVLYPKVYEQYIQTRNQYGNLSLLDTPTFFFGMRNGETVEIEIDKGKRLIIKL
                     ETISEPDENGNRTIYYAMNGQARRIYIKDENVHTNANVKPKADKSNPSHIGAQMPGSV
                     TEVKVSVGESVKANQPLLITEAMKMETTIQAPFDGVIKQVTVNNGDTIATGDLLIEIE
                     KATD"
     gene            complement(43829..45055)
                     /gene="ftsW"
                     /locus_tag="RPH49_000696"
     CDS             complement(43829..45055)
                     /gene="ftsW"
                     /locus_tag="RPH49_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDY5123885.1"
                     /translation="MKNFRSILRYIGKTSKFIDYPLLVTYIVLSLIGLVMVYSASMVP
                     ATKGTLTGGIDVPGTYFYNRQLAYVIMSFMIVFFIAFLMNVKLLSNIKVQKGMIITIV
                     SLLLLTLVIGKDINGSKSWINLGFMNLQASELLKIAIILYIPFMISKKMPRVLSKPKL
                     ILSPIVLALGCTFLVFLQKDVGQTLLILIILVAIIFYSGIGVNKVLRFGIPAVLGFLV
                     VFVIALMAGWLPSYLTARFSTLTDPFQFESGTGYHISNSLLAIGNGGVFGKGLGNSAM
                     KLGYLPEPHTDFIFAIICEELGLIGGLLVITLEFFIVYRAFQFANKTSSYFYKLVCVG
                     IATYFGSQTFVNIGGISATIPLTGVPLPFISFGGSSMISLSIAMGLLLIVGKQIKVDQ
                     QRKKQQQKVDIRRQFN"
     gene            complement(45369..45644)
                     /locus_tag="RPH49_000697"
     CDS             complement(45369..45644)
                     /locus_tag="RPH49_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDY5123886.1"
                     /translation="MAKQTTMKNAALKQLTKDADEILHLIKVQLDNLTLPSCPLYEEV
                     LDTQMFGLQKEVDFAVKLGLVDREDGKQIMLRLEKELSKLHEAFTLV"
     gene            45785..46267
                     /locus_tag="RPH49_000698"
     CDS             45785..46267
                     /locus_tag="RPH49_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123887.1"
                     /translation="MIQIKGAVKFPITLDSTTWIFDDRKVSIEDLEKGVFDGSKPIDF
                     EDNHEWNRAILEGQTNPPTLNSEIKYKKRAMLEGSFVINMTPFFKHSEPHDSATTIRL
                     SNEHDHLDIPIDLLPYLFFQFAKDGKRLYSDNGVDSFIYNQEDGYSYRINHVTHIEVI
                     "
     gene            46269..46436
                     /locus_tag="RPH49_000699"
     CDS             46269..46436
                     /locus_tag="RPH49_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaI family protein"
                     /protein_id="HDY5123888.1"
                     /translation="MRQVQCIICDAKVFIDERTTESKRLKNNPIRTFMCDDCKSRLDT
                     PKQRAQHYPLD"
     gene            complement(46576..48423)
                     /gene="typA"
                     /locus_tag="RPH49_000700"
     CDS             complement(46576..48423)
                     /gene="typA"
                     /locus_tag="RPH49_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDY5123889.1"
                     /translation="MTNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDER
                     AMDSNDIERERGITILAKNTAVDYKGTRINILDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQ
                     LEFPVVYASAVNGTASLDPEKQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYN
                     DYVGRIGIGRVFRGKMRVGDNVSLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDL
                     IAVSGMEDINVGETVTPHDHQEALPVLRIDEPTLEMTFKVNNSPFAGREGDFVTARQI
                     QERLNQQLETDVSLKVSNTDSPDTWVVAGRGELHLSILIENMRREGYELQVSKPQVII
                     KEIDGVMCEPFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNGLTRLIFNVPARG
                     MIGYTTEFMSMTRGYGIINHTFEEFRPRIKAQIGGRRNGALISMDQGSASTYAILGLE
                     DRGVNFMEPGTEVYEGMIVGEHNRENDLTVNITKTKHQTNVRSATKDQTQTMNRPRIL
                     TLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRIKQMMQENE"
     gene            48525..48716
                     /locus_tag="RPH49_000701"
     CDS             48525..48716
                     /locus_tag="RPH49_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaF family protein"
                     /protein_id="HDY5123890.1"
                     /translation="MKQKKSKNIFWVFSILAVIFLVLFSFAVGASNVPMMILTFILLV
                     ATFGIGFTTKKKYRENDWL"
     gene            complement(48870..49697)
                     /locus_tag="RPH49_000702"
     CDS             complement(48870..49697)
                     /locus_tag="RPH49_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HDY5123891.1"
                     /translation="MALYGFAQGLIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKA
                     TEDFIFDTILETYPNHQVLGEEGHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISI
                     GIYIDGKPYAGFVYDVMADVLYHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLT
                     KPILGEIFKEIVNDSRSARAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYE
                     VNGQASNLLGEPLTIGGPNSVLVGNRGVHREILDVYLEPHRDALIQLHERRFKRKSK"
     gene            49854..50468
                     /locus_tag="RPH49_000703"
     CDS             49854..50468
                     /locus_tag="RPH49_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YktB family protein"
                     /protein_id="HDY5123892.1"
                     /translation="MTKYTFKPKDFKAFNVEGLDARMEALNEYIRPQLHELGEYFSDF
                     FTSQTGETFYPHVAKHARRSVNPPKDTWVAFATSKRGYKMLPHFQIGMFEDQLFVMFG
                     IMHEAKDKATRAKVFERKFKAIQQLPDDYRVCLDHMKPDKPFIKDLTDDDLKEAIQRA
                     INVKKGEFFIARAITPQDKRLKSDKAFIAFLEETFDQFLPFYSA"
     gene            50652..52004
                     /locus_tag="RPH49_000704"
     CDS             50652..52004
                     /locus_tag="RPH49_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDY5123893.1"
                     /translation="MNNKRHSTNEQLSLDEINNTIKFDHRSSNKQKFLSFLGPGLLVA
                     VGYMDPGNWITSMQGGAQYGYTLLFVILISSLSAMLLQSMTVRLGIATGMDLAQMTRH
                     YLPRPIAIIFWIIAELAIIATDIAEVIGSAIALNLLFNIPLIVGALITVLDVFLLLFI
                     MKYGFRKIEAIVGTLIFTVLFIFIFEVYISSPQLNAVLNGFIPHSEIITNNGILYIAL
                     GIIGATIMPHNLYLHSSIVQSRTYSRHNNEEKAQAIKFATIDSNIQLSIAFVVNCLLL
                     VLGASLFFNSNADDLGGFYDLYHALKTEPVLGATMGAIMSTLFAVALLASGQNSTITG
                     TLAGQIVMEGFLRLHIPNWLRRLITRSLAVIPVIVCLIIFKGNAAKIEQLLVFSQVFL
                     SIALPFCLIPLQLATSNKDLMGPFYNKTWVNIISWTLIIILSILNVYLIVQTFQELQG
                     "
     gene            complement(52086..>52500)
                     /locus_tag="RPH49_000705"
     CDS             complement(52086..>52500)
                     /locus_tag="RPH49_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDY5123894.1"
                     /translation="RKPELIMAWIANSISIIYLLVMGLSYFSLKSGNASQREELAKQL
                     SQNGGNVSLDMLQTTIGALAIILLISTLYGIFATICIKGRRKLSIILFVIAIIVSLMA
                     LNLIAIVLWIIVMIMLISKKESKETTHKDDEYIYH"
BASE COUNT        17192 a         9587 c         7369 g        18352 t
ORIGIN      
        1 atcaacaaat tcaataatac ctcaaataaa aataataaca tcaaattcat cattattctt
       61 tttcggttgc attaaacctt attaatttgc acttaatttt aattaatgaa gtgttaactg
      121 gtaaatgtat gaaaccgttt gtaaaatagc agtgtactcg cattagtaag tacaaatcta
      181 ttttacaggg agaacttatt atgaaaaaaa atattacaaa agtaattatt gcatctacag
      241 ttatcgctac aggtcttcta actcattcaa atgatgctaa agctttcttt agttatgaat
      301 ggaaaggttt agaaattgct aaaaaattag cagatgatga gaaaaaagat gaagaacgtg
      361 ctgatagatt aattaaagac gccgagaaag aaagaactta tacaggtaaa acggttgaag
      421 atttatatgt cattgctaaa aaattaggta aaggtaatac tatagctgta gtgagaatta
      481 tagatggtgg taaaaacggt tactatacgt ttgatatcac gcgtccatta gaagaacata
      541 gaaaaaatat tcccgtagtt aaaaacggcg aaatcgattc aattacttgg tattaaaaaa
      601 cacactgaat taaatagttg cacgccaaac gttagaaaaa aatgctaacg ttttggcgtg
      661 cttttttata tgctgcaact tccaatttat ttagcatctt tacgactgct taataaagca
      721 cgtatgatta acacggttgc cactatatcc gttacaattt ttatgattgt taatacattc
      781 gatttccttt tcacaatagc cacctcgctt gatcaaaaca taaacaacta ttgcattcac
      841 ttttaaataa ttatttttcc caataagctc accattcaaa tgaacacaat attataaact
      901 aattatacct ttgaatatag caaaaagcca cactctaaag catggcttct atcaattatt
      961 ttaaagtatt atattttaaa actagatcga tttgtctttg taattttttc ttttcatagc
     1021 tgtgttggaa atgaattaaa ttaacagctc tttgtgcttt acggtgtgtt gcaacagttc
     1081 ttgtacgttt gaacaagttt acagcttttt gtgcatccac aactttttta tttacttgtt
     1141 ttttaaagtt tgtttgatac tcgttatatt tttttacagt ttcagcgttt ttagtttgtg
     1201 catgagattc accggcaaac gttgataccg ttaaactaat agcagctatg cttaaaattg
     1261 atttcccaat aaaattcttt ttcatagtta ataacaccta tcctcaaata tttattctgt
     1321 atatatttat aataatagag atatacaaaa aactacatta actatttatt aactaaacat
     1381 taatatttgt gtcactacat ttctgaattt caagaatttt gctactccat attttaacca
     1441 ccaaattatt gatataattt atgcctttag aaatcctttt aaatatgtat gcgattcatg
     1501 cttttaacta aattttcaat tttcctgact tcttggaatc ttaattttat actttttaac
     1561 aatacacttt taaccaaata atcaacatga ttcaaccata taggaccatc aacaatcaca
     1621 ttcctcaaaa gtacaattct tttcataaca taaatgtgtt attcattcca gttatcttat
     1681 aaaattgtca gaaatacttt taaacaaata ttcatgtcac gacctcctag ttaaatcagt
     1741 ctataaacta aaaaaagtca tagctacttt ctatttaaaa agtagtatga ctgattgttt
     1801 cgtgatgtcg atttttgaaa ttgacagtgc catgtaaagt ttgatcatca atcaagactt
     1861 cagcatatgt ttcttccatt gaacttctag attgagatat acttccagga ttaatcacat
     1921 gaacaccatt aatatattca tattttgcca catgtgtatg tccataaaaa gcaaatacac
     1981 aacctaattc gcgtgcttgc tcagctaata aatgtcttgt tcgattgact tgatataaat
     2041 ggccgtgagt ataaaaagca tacacgtcgt tacactttgc gaccgcttca ttttcaaatt
     2101 ctgggtaaaa atcacaattg ccttttactc tattaaataa gctaagttcc gtatcatcat
     2161 acgcgaattc tgaatctcct aaatgtaaat atacatctgc atctgggtgc atttcataaa
     2221 tttgatataa aacgcctgat tcagtatggt tatcactcac aataatccat ttagacatgt
     2281 tgatcacccg caagataagc ttctaataaa ttaattgcat ttcgtctatg gctaatttga
     2341 cctttttctt ctttagaaag ttgcgccatg gttttatcta atttcggcac ataaaatatc
     2401 ggatcataac caaaaccatt atcgccatat tttccatctg caatttcacc tgaaaccgta
     2461 cctttaaata cttttgtttc catatcaggg ccactcatac ttatgacaca aacaaattgc
     2521 gcacgacgat cagttgtatt accaagctta tttaataatt tttcaatatt tgcttcatcg
     2581 cttttatttt caccagcata acgtgccgag tatatacctg gctcaccatt taatgcaaaa
     2641 acttcaagtc cactgtcatc agctatgacc gttttattca atgcttttgc tgcagcttct
     2701 gattttaata tagcattttc ttcaaatgtt gatcctgttt cttccacatc aaaatctggt
     2761 attagttctg aaatacctat tacgtggtaa tctggaaata tcactttaaa gtcatttatt
     2821 ttcccttgat tattcgatgc aataacaatc tctttcatta aaaatcctcc tagtcattca
     2881 ctgatatacg ttccacattg acagataaat ttaaccactc tttgataatg ttagtaatgt
     2941 gagtaggatc acctgttgca aaaaatcgat gatctggatg ttcagtataa cttgcatgtt
     3001 cattactaaa tgttagcaat gcactaactt cacgagccgt ttctaatcca gacgaaatca
     3061 ctgtcttttt accaccaaaa taatcataga taggtttata gagcaatgga tagtgggtac
     3121 atcctaaaat gacagtatca gactcactat tacgccaacg tttcagtgtt tgatgaatga
     3181 caatgcttgt aattgttgga tcactatatc tcatttgttc tacaagtggc acaaaacctg
     3241 gacaggcaac gccatgtacc tctacatgtg gattgatacg tttaatatgc gtacgatatg
     3301 cttcagattt aattgtgcct tccgttccta gtactaatac attttgattt ctagtagtca
     3361 ttattgctgt tctagcacct ggttcaatta cgccaatcac tgggattgat aaggtctttt
     3421 gtaaatattc taaagctaca gcagttgctg tattacaagc aatcacgagc atttttatat
     3481 caaattccat taatttacga gcgatttcaa ctgtatattg ttttacttgt tctcctggtc
     3541 ttggcccata tgggcatcgc ccaatatcac ctaagtaata aatcgtctca tttggcaact
     3601 gacgcataat ttctttagct actgtcaaac ctccgacacc agagtctatt acacctattg
     3661 gtttattcat attcggtcat ccttactttt aatttaattt ttagtttatc ataactaagc
     3721 attggatttt agtattatgc actgtgttta ccatttttgt cattataata tttattttaa
     3781 atcagcccac tatcatattg tcatgtaatc tgcttattaa aaaaatccct tccaagttat
     3841 tgtgtatctc cattcaattt aattttgaaa ggaacataac attttaactc aaaagggatt
     3901 aatttttatt ctacttcatg gtctgaacca aagaaagatt taaacatgtg gaatgttgtt
     3961 tctctgttca ttgctgcaat ggatgttgtt aatggaatac ctttagggca agcattaaca
     4021 cagttttgtg aattaccaca ctgctgtaag ccaccagtac ccattaatgc atttaaacgt
     4081 tcatctttag tcatagatcc tgttgggtgc aaattaaaca aacgaacttg cgagattgct
     4141 tgcgcaccaa cgaatttatt attttcagta acattaggac aaacctctaa acatacacca
     4201 catgtcatac atttagataa ttcataagct gtttgacgtt ttttctctgg catacgtggt
     4261 cccggaccta aatcatacgt tccatcaatt gggatccatg ctttcatacg ttttaagtta
     4321 tcgaacattc tagaacgatc aacttgtaag tcacggataa ctgggaatgt attcataggc
     4381 tctaatcgaa taggctgttc taattgatca acaatcgctg aacatgattg tcttgcacga
     4441 ccattgataa ccattgaaca cgcaccacat acttcttcta aacagttcat gtcccatact
     4501 actggcgttg ttttttcgcc tttaatatta actggattac gtctaatttc cattaaacat
     4561 gcaatgacat ttaaattttc acgatacgga atttcaaacg tttcttcata tggttttgaa
     4621 tcacttgtat cttgacgttt aataattaat tttactgttt tttgtttcgg tttagattgt
     4681 gtttcatgtt gtggtgtgtc ttttactggt tggtcagtca ttatttttta ccccctttag
     4741 acttacttgt gtaatcacgt ttacgaggtg gtattaaact cacatcgacg tcatcataag
     4801 taaactgtgg tttttcaaat gcaccttgga atgaggccat tgttgttttt aaccactctt
     4861 cgtcattacg ctctgggaat tctggtttat aatgggcacc acgtgattca ttacgattat
     4921 atgccccaat cgtaatcaca cgtgcaagta ctaacatatt ccatagttga cgagtgaaga
     4981 ataccgcttg gttactccaa gtttgtgtat cttccatatc tatattttca taacgcttca
     5041 tcaattcaac aatcttttta tctgtttcta acagtttttc attttcacga acaactgtta
     5101 cattagctgt cataatttct ccaagttcac gatgtaattt ataagcattt tcagtaccac
     5161 gcatagccat taatttttca aaacgttctt gttcttcagc tttacgtttt tcaaaaatac
     5221 tttcatccat atcagtatat gaacgatcaa tattagcaat ataatcaatg gcattcgggc
     5281 ctgcaactgt accaccgtaa atcgctgaca ataatgaatt ggcacctaag cggttaccac
     5341 catgttgaga gaagtcacat tctccagctg caaataaccc tttaatattt gtcatttgat
     5401 cataatctac atatagacca cccattgaat agtggacagc tgggaaaatc ttcattggta
     5461 ctttgcgtgg gtcatcacca gtaaattttt cataaatttc aatgatacca cctagtttta
     5521 catctaactc atgtggatct ttatgtgaca aatcaagata taccatgttt tcgccattaa
     5581 tacctaattt ttggttaata catacatcga aaatttcacg cgttgcgata tcacgaggta
     5641 ctaagttacc ataatcagga tatttctctt ctaagaagta ccaaggctta ccatctttat
     5701 atgtccaaat tcgtccacct tcaccacgtg ctgattcact cattagtcga agtttatcat
     5761 caccagggat tgcagtagga tgaatttgaa tgaactcacc attagcataa atagcgcctt
     5821 gttggtaaac aatggaagcc gctgatcctg tattaatcat tgagtttgtt gttttaccga
     5881 aaataatacc ggggccaccc gttgccataa taactgcatc tgaaccaaat gtttcaatct
     5941 cagcagttgt catattttgt gcaacgatac ctcttgcact atcatcgtca cctttaacta
     6001 tgccaaggaa ttcccatcct tcatacttcg taactaatcc atctacttca tatgcacgaa
     6061 cttgttcatc caatgcatat aataattgtt gtccagttgt tgcccctgca tatgctgttc
     6121 tgtggtgtaa tgtaccaccg aaacgtctaa aatctaatag accttcattt gttctattga
     6181 acattacgcc catacggtct aataaatgaa taattttagg tgctgcctct gtcatcgctt
     6241 taacaggtgg ttggtttgca aggaagtcgc caccatacac tgtatcatca aagtgaatcc
     6301 aaggagaatc gccttcccct ttagtattga ccgcaccatt aatgccacct tgggcacaaa
     6361 cagagtgcga acgctttact ggtacaactg agaacaaatc tacatgtgca cctttttctg
     6421 ccgctttaat tgttgacatt aagcccgcta ggccacctcc gacaacaata agatgtttct
     6481 ctgccataaa aatttcactc ccctaaattt tcaatctata tttgttaaat gcgatgtatt
     6541 acataaaggc aataattgca gtaacaccaa tatacgaaat aactaagaat acgattaatg
     6601 aaacccatgt aaatactcgt tgtgattttg gagattgaag tcctccccaa gtaactaaga
     6661 atgaccataa gccatttgca aagtggaaca caacagcaat aatacaaata atataaaata
     6721 ttgcccatcc aggatgttgc aatgtttcgt gcattaaatc gtaattcact tctttgccgt
     6781 aaaatgcttt ttgtaaacgt gtttgccata aatggatacc aataaagata aatgttaaga
     6841 taccactcac tctttggaag aagaacatcc agtttctaaa aatcgagtaa tgtccaacat
     6901 tttcttttgc tgtaaatgca atgtgtatac caaacaaacc gtgatataac aacggaatgt
     6961 atataaataa aaattctaca ataattagaa atggtaatga ttccataaag ttagatgcct
     7021 tattaaacgc ttcagcacct tgtgttgctt ggtgattcac taataaatga acgaccaaaa
     7081 atgcacctat tgggataata cctaataacg agtgaatacg tcttagataa aattcatttt
     7141 ttgattgagc caaaaggagt cccccctgtg aacgaatatt taatttattg agctatttat
     7201 attaaacgta cgcttaaccc cctaaagtga tatcgtttct agcgttgtca ttatcattaa
     7261 gcgaaacatt ttaaagacaa atacacactg tacgatcacc aaactgcatg tcgaacaatg
     7321 taacatttgg attcgatatt taaaattgct tgtgatgata aactttctca tttagaaaac
     7381 gcttccacgt acattcaaaa aaataacttt gttaaccata ttgtaacatt atttcatata
     7441 ttttggggca tgagaatgat tctcacgccc agtaatttat ttatgcaatt gttcatgtag
     7501 gttctttgcg acgttttcag gaatacctat atttttaaaa tcttcaagtg tagcttcctt
     7561 cattttcttg attgaaccga atgaacgtaa taataatgtt ttacgtttgc taccgatacc
     7621 ctctatatca tcaaggattg atttcaagcc tgtcttttga cgtgtttgcc tatgaaatgt
     7681 gattgcgaat ctgtgaacct catcttggat acggtgcaac aaataaaatg cttggctatt
     7741 tttcttcagt ggtactattt ctgcactagc gccatataat aattcagatg tttggtgttt
     7801 atcatttttc tgcaaacctg caacagggat atcaagacct aattcgtttt gtagcacatc
     7861 aataaccccg ttcatatgtc ctttaccacc atctactatt attaaatcag gtaatggtaa
     7921 tccttcgttt aaaacgcgag aatatcggcg tcttactact tctctcattg atttgtaatc
     7981 atctggacct ttaaccgttt tgattttata ctttctataa tttttcttat ctggtttacc
     8041 gtcgacaaat gtaaccattg ctgacactgg atccacacct tgaatattag aattatcgaa
     8101 tgcttcaatt ctaattggtg tttgaattcc catttgtgtt ccaagttctt caatagcttt
     8161 aattgttctg gactcatcac gtgatattaa ttcaaattta ttatttaaag atactttagc
     8221 gttatgtgca gctaggtcaa ccatatcttt tttgggacct cgcgcaggtt gaacgatttt
     8281 agtgtccaca acagattgaa tcatttcttt atccaaatta cgtggtacat gaacttcctt
     8341 aggtaaaata tgttggttta agctataaaa ttgtccaata aatgtataaa attcttcttc
     8401 ttctgtttgc tgtaatggaa tcatcgttgt atctcgcttt atcatattac cttgtcgtat
     8461 aaagaaaact tggatacaca tccatccttt atcaacgcta taaccaaaga catcacgaat
     8521 cgttttatct gatgacataa ttttttgttt gttagttaga ttttgaatat gttgaattaa
     8581 atctctatat tctttagccc gttcaaaatc aagtgattca cttgcagtta acattcgctc
     8641 ttctaaactt tttaaaattg ttttgtcttc cccattcaga aaatcagtaa tttccttcgt
     8701 catttgtgcg tatttactca aatcaacgtc atatacacat ggtcctaaac attgtccaat
     8761 atggtaataa agacataatt tatctggcat cttatcacat ttgcgatatg gatatattct
     8821 gtctaataac tttttagttt cttgagcaga atatgcattc ggatacggtc cgaaatattt
     8881 gccagtacct tgttttacag ttctcgtcac tagtagtcta ggatattttt ccttcgtaat
     8941 tttaatgaat ggataacttt tatcatcctt taataatata ttatatcttg gttgatattg
     9001 tttaatcaga ttcaattcca gtaaaagtga ctctgtttca cttgacgtga caataaattc
     9061 aaaatgccgt atttctccaa ccagtctcgt tgttttagca tcatgagcac ccgtaaaata
     9121 tgatctcaat cgatttctta gctttttagc tttgccaaca tatatcactt gatcattacg
     9181 atctttcatt aaatagcagc ctggttccat aggtacgaca tttaatttat ttttaattcg
     9241 ttgcttatag tcttccaata atatcccccc ttctaatttt aaaatgaatg atgctacaaa
     9301 agtgcttcaa atttatcacc actaattcta gctcataatc aacatcttcg agtatgactt
     9361 ttcatgcaca tcatgtaaaa ttgaacattg ttttatcaaa ccaactgcta caaatctatc
     9421 agcatgctag attatcattt aacgttcata gatttattaa tcccaccatt ctcaagtcgt
     9481 aaacaatatg atgacttatc attcaacttt ttatattaaa aacacaaaca aaaactggag
     9541 caattcatta aagaaatgcc ccagtcgtca ttggttgtaa cttataaatg tttatctaaa
     9601 acttcagcta agttttcttt tggttggaaa ccaacaactt tatcaactgg ttgaccgtct
     9661 ttaaagacga ttaatgttgg aatactcatc acttcatatt tagctgcagt agatggattt
     9721 tcatcaacat ctaattttaa aatgtcagct ttaccttcat agtcagctgc taattcttct
     9781 aataccggag cgatcatttt acatggacca caccatgttg cccaaaaatc tactaattgt
     9841 acaccagatt ctacttttga atcgaaatct gcatctgtta cttttacgat tgccataaat
     9901 gccaatcctc cttaattatt attatgatgt tcaaattata tcagataaca tgcttcatgt
     9961 atttctattt gctcaatttt tatgcttatt tcaaataaca tgtttgaaat gtattcttgt
    10021 tgctttacat tattttaact gcagctattt aatttatcaa attataattt attttagtgt
    10081 tgcaacggta acgccaaatc caccttcgct tggcatacca cctctaaagt cactaacact
    10141 tttatgcttt ttcaaatgtt gttgtacacc tttttgaagt gcacctgtac ctttaccgtg
    10201 aatgatataa acttgttcgt aattacttaa aactgcttga tctaaatatt gatctagttc
    10261 aattaaagca tcctcataac gatagcctcg taagtctagt tcagttttaa ttgtttgacg
    10321 gttttgacgt gtaaccattt tcgttggctt aactttttct ttttgttttt tctctaaatc
    10381 ttcaataggt aacttcattt taataattcc catttgaaca attgcttctt catcattgac
    10441 aatttctaaa acttcaccct tttgaccgta agataatact tttacttcat caccagcaac
    10501 aattttatcg tatttttgct tttgtacatt ttgctttata gatttcgctt cataatgatc
    10561 atctaatcgt ttcttcttat caatcaattc atgttcttta acatctgcac ctttttgttc
    10621 acgcaattgt cttaagtctt taataatatc gtcagcttct tttgttgcag ctttaatctt
    10681 ctgatttgct ttttctttcg cttcctctat tagagacttt tcataatttt ggaattgttg
    10741 atactgctta gataaatcat catgcacttg ctccgcttct tttacaagac ggtccagttc
    10801 taacctctgt gtctctacac gtttgtaatt acgctctaat gattcaatca tttcatttat
    10861 ttctttttca tcagtaccaa tcatcgtctt agccttatta ataatattca aactaagacc
    10921 taacttttta gaaatgtcaa aagcatttga acgacccggc acacccatta ataacttata
    10981 cgttggactc aaagtatcta catcaaattc tacactcgca ttcataacgc cttctcgatt
    11041 ataactatat gctttaagtt caggatagtg cgtcgttgcc attactagag aaccaatttt
    11101 tctaacatga tctaaaatgc tcattgctaa tgcagcacct tcacttggat ctgtacctgc
    11161 acctaattca tcaaataaaa ctaaactatg tttgtctgca tgctttaaaa tttcaactat
    11221 attcgtcata tgagatgaaa aagttgataa tgattgttct attgattgtt catctccgat
    11281 atcgcaatat acatttttaa atatacttaa ctgactacca tcaagtgttg gaatcaacaa
    11341 tcctgattga gccataacaa taattaaacc taatgttttt aatgttactg ttttaccacc
    11401 tgtattcggt cctgtaataa ttaccgtttc aatatcttcc ataaattcga tggtattagc
    11461 tacaacagtc tcacgattta ataatggatg gtatgcttta ggtaaatata cagtacgttc
    11521 ctctttaaat atcggctttg ttcctttaat acttctacta tatctcgctt ttgcgattaa
    11581 aaaatctaac tgacccatga cttgttctgc cacaagtagt gcatctttgt ccgcagccac
    11641 ataaccagtt agttgcgtta aaatgcgttc tttttcaatt gcttcatcat gacgtaatcg
    11701 actaatttga ttattcattt caacaactga tgatggctca atatacaatg tttgtcctga
    11761 agcagattga tcatgtacaa tcccattaaa atcttgtcga tattcagctt tgacaggtat
    11821 aacgtttctt tcattcctaa ctgttacaat tgcatctgat aattttttct gatttgcttg
    11881 gcttttaaca atacggtcca aattttgtct aatacgttga ttcgtgctag aaattttact
    11941 tctaatccct tgcaattcat aactcgcatt atcatataaa tcatacgtat cgcatgtttc
    12001 atttatttgt tgaaaaagat cggttaacac aggtaattga ttcatcttgt catctaatat
    12061 tgggtattta acaccttcat cttcttcaac caattgatta taaaatgtct taaattgatt
    12121 ttgtacttga attaatcttt ttatcaagtt aagctctgat acatttaaaa cgccgccaat
    12181 atcagcgcga tgaatgaatg ctgatacttt agataagcca ctcaagcttg gtaaacgatg
    12241 cttattatag atttgagcaa tctcatccgt ttcttccatt tgaaaaacaa ccgtttcaaa
    12301 attagtagct ggcatcattt gattgacctt ttccaagcct aagtcactaa ttgtttcatt
    12361 ggcaacgagt gattttattt tttcaaattc taagacgtct aatgtttttt gtctcataaa
    12421 atccctctat ttcttaagtt ttatattatt ttcaataaag tctttaaaag cttcacgcga
    12481 taatgcgtta atcactctat cttttgttac aaatcctttt tgcgcagttg ctacgccata
    12541 attcataaaa tctaaatgat ttgtatgatg cgcatcagtg ttaatagtta atttcacatt
    12601 tggatattta cgaacgatat cagcgttcag atccaatcga tgtggattgg cattaatttc
    12661 taatactgta ttcgtttctt cagctaatgc cattaattgt tcaatattcg gtttataacc
    12721 atctcttcta cctataatac gccctgttgg atgcgctata tgtcgcacgt atggattgcg
    12781 acatgcatta gctaatcgtt ccataatttg ttcttctgat tggttaaagc tttgatgaat
    12841 agctccaatt acataatcaa gttgtgctaa aatttcatca tcataatcca gcgagccatc
    12901 agttaatata tccatttctg tacctgaata aatatcaatt tcactatatt ctttatctaa
    12961 agccttaatt tcttcgtttt gtcttaaaag tctttctact tgtaagccat tagcaacacg
    13021 taaactttgt gaatgatcag taattaccat gaatttataa ccttttgcga tatttgcttc
    13081 taccatgtct cgaatagaaa acgcaccatc actatacgtt gtatgcatat gaatatcacc
    13141 attaatatca tctaatgtaa tgatattact tagatcttta tcaaattcgc taccatcttc
    13201 tcgcatagca ggtggtataa aattcacatt aaaatgttca tatatcttgg cttcactatc
    13261 atattgaatt aatgtaccat cagcttgttc aattccatat tcacttactt tttcatcacg
    13321 tgctttagca agttgtcgaa ttcttatatt atgttctttt gacccagtaa aatgctgcaa
    13381 tgtatgataa aaagcacttg gttcaattaa tcgaaaatcg acaccaatcg tttcatcatc
    13441 atacgctaat tctaatgaaa cttttgtgtt ccccactgca acttctttta ctttattggg
    13501 aatatttaat aattgctgct gcactgcttt tgggttatcg gtacttatta tgaaatctaa
    13561 atctttgctc atttctttaa aacgacggaa gcttcctgca gatgaatatt gatcgatata
    13621 atttaatgta tctatataat caatgatttc ttgattaagt cttctcattt gatcaattgg
    13681 atatctatct ttcttagcac caagttgttt cacagcttct aatatgtttt gttccgtttt
    13741 cttagcaaat ccgcttaatt cactaacttt tccattttca caagcaactt gaagtgacgc
    13801 tttatcaaca atattcaact ctttatatag cttagcaatt ttcttgcttc caagtccttg
    13861 aattttcaaa agtggaataa gaccttccgg aacttcttcc tgtaattgct gtaaatactg
    13921 agattcaccg gtctcacggt aatcattgat tacttctgca acacctttac caatgccttt
    13981 taagtccgtt acatcagata tttcatctaa tggtcgttca tctaattcaa gactttgagc
    14041 tgcttttcga tacgctgata ttttaaaagt attttcccct tttaattcca tataagtagc
    14101 aatttgttct aatagtttga taacatcttt ttttgtcata ataacactcc ataaaaagaa
    14161 gaccaggacg tatcattaat atataccttt gtcctgacct cttatgataa tttataaatt
    14221 aatggtgaaa gccgataaat atgggatgtg aaaaatcaat gaatgactca caatagatat
    14281 tttaagctga tgttgtaatg cttcgttagg atataatgcc aatagatata acgtaaagtg
    14341 taagacaatt atcgtcataa acacaccaac tatcattccc attgcacgac tgaaaatatg
    14401 aatgttttga tacgctatta ttttatcaaa agttacgata attagataca aaatgaactt
    14461 acaaaacaat gtaatcatta aaaaagctac aatcgcttca aatcgatttt gtagatgatt
    14521 aaaatgaaac gcaaaagttg tattaaatgc tgttgtttta ggatatggaa taaatacaat
    14581 taatctttct acaatagatt tgtaaaattg actggcaatc cacaatgata caatcgttgc
    14641 actcaaatgt atcatagata accaaaaacc tcgtctgaat ccaacgatga caaaatacac
    14701 aaagaaaatg attatgataa aatcaatgac catttattgc tcacgctgct gcaatttgtg
    14761 aatttgttgt ttcaaacgtc gattttcttc ttctagtagt actttttcat gcataatatt
    14821 cacagcagtt aatattgctt ttcttgaagt atctaaacct gctgctttat accctaattc
    14881 ttttatttta tcatcaacta aatgtgctac atatcgtatg tgctctgggt tatcttcccc
    14941 aacaattgta aaaagctgat cattaattga tacatttacc ttgtttttaa actgtgccat
    15001 ttataatttc tcctgatcct ttttttaaaa tctaaattca cgttataaaa tatgactgga
    15061 tagtttgtct gaatttgata ctaatattgt tatattgcaa ttatgataaa acaacaacac
    15121 aatctctata gatgacttaa tgttcttttt ataatgaaat gaaataatgt aaagaatttt
    15181 ctattcaata ctttatcatg tttaaattgt gtcactataa cattttcata aacattatac
    15241 atgaccacta tgtattttgt aagtatccgc aattaattct ttacaacata tataaatgtt
    15301 tctgacgtta ttatcattta tgatatgatt atttttgcta atgataatga aattatatga
    15361 aaggatttac acaaatggcg aatatcgttt ttaaattgtc ggataaagac ataacgacat
    15421 taatgtcacg aatttctttt gatactgaga atttacctca aggtatgaaa gcacgtgcaa
    15481 agtatcaaaa tacaactgta aatatttacc aatcaggtaa agtcatgttt caaggtaatc
    15541 atgcagaagc tgtgtctcaa gaacttctac cgcagcattc tcaattgaat actaataaaa
    15601 ctaaaaagaa aaatatggct aattcttttc ttgaacagtc tttaatgtat gatcaattta
    15661 actgtattgg tagtgatgag gctggaagtg gcgattactt tggtccattg actgtatgtg
    15721 ctgcttttgt taccaaagag catgtcctta ttttaaaaac tttgggtgta gatgattcaa
    15781 aaaaattaac cgatactaaa atcgtagaac ttgctgagca attggttact ttcattccac
    15841 attcactatt aacactacac aatgaaaaat ataatattca gcaagcaaaa ggctggactc
    15901 aagtaaaaat gaaagctgtt cttcataatg aagccatcaa aaatgtactt gaaaaaattg
    15961 attcgtctca attggattat attgtgattg atcagttcgc aaaacgcgaa gtgtatagcc
    16021 attacgcatt atcagatata ccacttccaa agaaaacaaa atttgaaaca aaaggagaat
    16081 caaagtcatt agccattgca gtggcaagca taatttctcg atacgcattt gttacatata
    16141 tggatcaaat atcaaaaaat attaatatga cgattcctaa aggtgccggt gctaaagtcg
    16201 atgtaatcgc cgccaaaatt ataaaaaaat acggtctttc acgtttagat accatttcaa
    16261 aaaagcattt taaaaatcgt gaaaaagccc aaaaaatttt aaagcctctt tgatttataa
    16321 tcattagagg cttttatgca gttgtgcaaa gcaccaactg taatccgctg tgcctctttg
    16381 atttttaatc attatgaatc ggaacctaat aggtgattct attaggtaag tcatactaat
    16441 ttgctttgct cataagtatg actttatatg cagtgatgcg aagcatcatc tgtaatccgc
    16501 tgtgcctctt tgatttttaa tcaagataaa ttggatccta ataggaaatc ctattaggta
    16561 agtcatacta atttgctttg ctcataagta tgactttata tgcagtgatg cgaagcatca
    16621 actgtaatcc gctgttcctc tttgactttt taaatgcatt ggaacctaat tggtgaaccc
    16681 aaaaataaaa ccccatgtta gggatatcaa tctacttcag atatccttat acatggggtt
    16741 taaatcatta tctaataaca gcaccttgtt caattaatgc tgcttcaatt tccgcttgta
    16801 cttttgaaac gcgctcatct gtcaatgttt cttctgtgtc taaataattt aaacgtattg
    16861 caattgattt tttacctttt tctaaatgtt cgccctgata tacatcaaag acaagtgtat
    16921 cttttaatat attgccaccg tgtgcatgaa tcgttgataa taaatcagct gctggaatat
    16981 tttgatctac ttctaatgca atgtcacgag acatgcctgg gaatctcgga attggctggt
    17041 aattaatgta acctaccgac acagccatta atgcatcaaa attcaactca aaaacatacg
    17101 tacgttttaa atcattatca gctgctaatg ttggatgtaa ttcaccaata aaaccaacaa
    17161 ctttattctc taataagatt tcagcagtac gacctggatg taatccatca atatcagcac
    17221 gacgataact aaattcaagg tttaactttt cagatactcg atccacgaca ccttttgcta
    17281 aatagaaatc aaccgtttct ttcttacctt gccattgatt gactacataa tctccagtta
    17341 aaataccact taaatattca acttgatctg gtagttcacc ttctccatta gcaaagaaga
    17401 cattgccgat ttcaaataat tttacatctt tatttttgcg tgccacatta tatgatgccg
    17461 cttcgattaa atgtggtaat aaactttgac gtaatgacgc atgcgcttca ctcattggca
    17521 tcaataaatc aattgtttga cgctgttgca tcgcaaatgc agtagcatct tctttagaaa
    17581 ctaacgaata cgtaatagct tggtctaatc cagcaccttc taacacttct ttaaccattc
    17641 tcgttttata ttggcgatca gttagctgac cactagtaac tttttcgaag acaggtaacg
    17701 ttgatggaat atcgtcgtac ccataaatac gtgcaacttc ttcaattaaa tcttctttaa
    17761 ttgtaatatc tttacgacgt gatggtactt gcactgtaat aacatcatca tttatttctg
    17821 tatcaaaccc tagttgatta aaaatagtaa caatatcatt ttgtgacaaa tcaaatccaa
    17881 tagtgcgatt aattttatca gcagtgatgt cgattggtgt aataaatgca ccaagttctc
    17941 ctgaagacac tctatctttt agcacttttc cgtttgcata agtttgtaat aaataacatg
    18001 cacggtcgac tgcttcatct acaaattcag tagctattcc tttttcaaaa cgactagatg
    18061 attcactgcg taaatttaaa cgtcttgatg tatgacgaat tgaaactgga tcaaaaatag
    18121 caccttcaat cactatattt gatgtatgtt ctttaacttc tgaaaaatcg ccacccataa
    18181 caccagctaa tgcaattgga gtttgtccat tagtaatgac aatatcgctc gttaataatt
    18241 cacgttctgt atcatctaat gttgtcattt tttcgccttc attcgcttga cgaacaacaa
    18301 tttgttgtga accaatcgca tcttgatcaa acatgtgcaa tggttgaccg tattctaata
    18361 acacataatt tgaaatgtca acaacattat taataggacg tatacccgct tttattaagc
    18421 gtgcttgcat ccaaattggc gaaggttcaa ttgtcacgtc gtgaacaaca cgtgcactat
    18481 aatatggtac tttatcttca ttttcaattg tcacagtcag ttcatcattt gcagataact
    18541 caagctcatt tgatgttgtg tctggcttag tcatttttgt attatataat gctgcaactt
    18601 cataagcagt acctatcata cttaaagcat cagcacgatt cggcgttaaa tcaaattcca
    18661 ttacttgatc atctaaatat aaagcttgta aggcatctgt tcctggaact tgggattcac
    18721 taaaaacata aatgcctgat tcaaaacttt tcggtacata gttacttgaa ataccaattt
    18781 cttgtaacga acaaatcata ccttctgaac gttcaccgcg taatttggca cgcttaattt
    18841 taataccacc aggcaatctt ccacctactt tagcaacaat gacatattgt cctgcatcaa
    18901 cgttcggtgc accacatacg atttgtacag gttcgtcttc tccgatatca acttggcaaa
    18961 catttaattt atcagcatca ggatgtttct cttttgactt aacgaagccg acaactaaat
    19021 ttttgatatc ttttgtgtag tcaattaaat catccacttc aatacctgtg cgcgtaatac
    19081 gttctgccaa attacttaca gaatcatcga ttgttacata ttctttcaac cattcatttg
    19141 atatcaacat tacatgtcac ctctatcttc taccgcttta aattgatcta aaaatctcac
    19201 atcattagta tagaaatgac gaatatcttc tataccatat tttaacattg caatacggtc
    19261 tggtcccata ccaaatgcaa atccagagta ctctgaagaa tcaaaaccag ccatttctaa
    19321 tacattagga tgtaccattc cagcacctaa aatctcaatc catcctgtgt gtttacacac
    19381 attacaacct tttcctttac atttaaaaca tgacacatca acttctacag aaggttcagt
    19441 gaatgggaag taacttggac gtaaacgaat ttcacgatca gcaccaaata atttcttagc
    19501 taacaattct aaagtacctt tcaaatcact cattttaacg tttttatcaa caactaatcc
    19561 ttcaatttgt gtaaattgat gactatgtgt cgcatcatca gagtcacgac gatacacttt
    19621 accagggcaa ataattttaa ctggaccttg accatgacgt gattccatcg tacgtgcctg
    19681 cactggtgat gtatgcgtac gtaataaaat ttcatccgta atatagaaac tatcttgcat
    19741 atcacgtgca gggtgtgatt taggtaaatt cagcatttcg aagttataat gatcttgttc
    19801 aacttcatat ccattcacaa tttcataacc taaacctaag aataagtctt caatttcttc
    19861 tattgtacgt gttaatggat gctttgaacc gatttcaata tgacgacctg gtaatgatac
    19921 atcaattgtt tcttcagcca attgcttatt taatttttct ttaactaaca tctgttgtct
    19981 ttcatctaat tcattttgaa ttgtttgacg caattcattc actttttgac caaatgcagg
    20041 tttctcttca ttcggcaaat ccttcatcaa tttcattagt ccgctaactg accctttttt
    20101 acctaagtat ttcactttaa cttcttgcag tgcacgttca tcatttgctt cattaatatc
    20161 tacaagcgct tgttgtttta actctgacat tgtttgttgt tcagacatat gtcactgacc
    20221 tccctattcg aactattcat tttctattta tcatatttgt tgtttaacta aaaaaagact
    20281 ttcatcctct taaaaaataa gggacgaaag tcatttccgt ggtaccaccc aaatttatgc
    20341 ctaagcatac acttgtttaa tattgataac ggattgtctt tccgacttaa atctctttaa
    20401 gtaaccaaaa aggtgaaaag actttaaata attggaataa cttgcagtca cgattattct
    20461 ccctaaaaca attatttata taaatgtcca tgccttttta ttggtttata ttcaattgtg
    20521 tatgcaatca cgtagaaatg ttctgttaaa caattaatta taattatatc ggaaaacttt
    20581 caacacggtc aacctttcaa atgataaagt aaaatactac ctgcaatcgc tacatttaaa
    20641 ctttcagctt taccataaat aggtatgatt aaattttgtg tagtatgtgc taataattca
    20701 ggattaacac cttctccctc attacctaat agtaatgcaa aagaatcact tgaagtaact
    20761 tctttgtatg ccactgcgtt ttcaagtgct gtaccataaa caggaccatt aaattgagta
    20821 ataaacgtat cgagatcttg agtcataact ggcaaatgaa aaacactacc ttgactcgct
    20881 cgcaatactt tatcttgata aggatctgtc gtacccttct ccattattac agcatccatt
    20941 ccagcagcat ccgcagttct aattaatgtg cctaaatttc caggatcttg aacacgatcg
    21001 ataagcaata cttgttgtgc tttagaaata tcatattgtg gcttctcaat gattgcgaaa
    21061 aacccttgtg gtgtcactgt acctgataaa gattcagcaa ctttcatgtt tatttcaaaa
    21121 acttcttgcg cgtatgcgat aatttgctga tctaatcttg ccggttcaat tgcaaataat
    21181 tgtgtaatta caatcccact ttgataagct tcttcaatta aatgcacacc ttcaattaaa
    21241 gctaatccag ttttatccct ctcacgtttc ttttttagct tgttcgcttg tttaattcta
    21301 ttattttgtg cagaagtaat ttgttccata gatagctcct cgctttattt ttaaaaataa
    21361 aaatattaat cattaataag atgaaaacat ttgattgtat agttaatatt aattaatcga
    21421 ttttatcact catattattt caaattgtat aaatttcttt tatcgatact actactataa
    21481 atcatacgcc ccaaaatatc attattaatt cttttcttct tcaaaataaa tcaaaatgat
    21541 ataattgatg attattttca aagcacattc aaatcaaact acgctttagc aatttgttgt
    21601 tagcatgttt gtgttcatta aaaaaacgac catcatcggt atcatgtatg gtcgttacaa
    21661 aagctaacaa taccaattgt cataacaagt actgcaacct ctttaaattc aattatttca
    21721 tgtaactata gcctatatca tatgtaatta ctttgttatt gataatcggg ctactttcat
    21781 cttcattttt acttctaaca tgtttatgtg ctgctttaaa gacatcagat tttaaccaat
    21841 ccgtaaaagc ttgctttgat ttccaaactg ttaaaatttt cacttcatca aaatcttctt
    21901 gttctaaagt ttgtgtaaca aacatgccat caaagccttc taatgtttca atcccatgtc
    21961 tcgtgtaaaa tcgttctata atatcttttg ctgttccttt tgttaacgtc agcctatttt
    22021 ctgccatgaa tttcataatt atcctctttt ctgtttaact taccttaatt atttttgcga
    22081 caacaacaat tcttttcgtt gtttcactat atgcatcttc gcacgttgat aaagttatta
    22141 ttttatcttt taccgttaca ttaacatctg aattaattac agatttacgt tttgtctcat
    22201 ctaaaaattg ttgataatct tgatcatttt caaaatctgt acgtatgtaa ttatctttag
    22261 tagtagtttt atatgcacta aatacttgca attgatattt accatattta ttgtcaaatt
    22321 caattatctt gtgtttttca taaaaagatt gctttaaata atcttctaac acatcaaaca
    22381 tcgtattatc accgacatgg tgcccatata aaatagtatt atgatttaaa ttcttcaatt
    22441 catttctaaa atccataaaa atactacctt tacgtcgatg ttctcgctca aaatctaaat
    22501 ttaaataatc gtgatttgtc ttaccttgta gtactggata atttaatgat gttcctgata
    22561 attttatcca tccaacaatg tctttattta ttttttcaag tgattcaaat tgtggtctca
    22621 catgtgcttg atgtttgctc atcagcattt gaaatttttg ttgtaatttc tcataatttg
    22681 cgcgttcttg cttgtcttca atatatgttt gaacaatttt gtaaccaaaa atgataataa
    22741 ttacaaccaa taaaatttgt acaatagtta aaaatcgctt cattctcata aaaatcctct
    22801 tttattaacg acgtttcttc agtcactact aaaccagtta ttgtaccgtt ttagattcga
    22861 tttcgttgac tttgacaaat taagtaaatt agcattggac caccgacaat cattaaaata
    22921 gcattggctg gaatttctaa aggaggctgt atcactcgtc ctaataaatc agccactaac
    22981 aatagccatg caccaataac tgtagaaaat ggaataagta ctctgtaatt gcccccaact
    23041 agctttctaa ccacatgtgg cacaataata cctaaaaagg ctagttgtcc aacaatcgca
    23101 acagttgcac ttgctaaaaa tactgctaat aaacctgtta accatctgta acgatcaata
    23161 ttgaaaccga tacttcgcgc ttgtacgtca tctaaattta gtaaattcaa tttagtggac
    23221 aatagtaatg ttaatattaa tcccaataat gctgatactg ctaatatgta tacgtcgctc
    23281 catattttca ttgttaagcc ttgaggaatt ttcattaaag ggttttgagt taaaatttct
    23341 aaaacaccat ttaataatac gaataacgca acacctacta atatcatact tacagcattg
    23401 aatctaaatt tagaatgcaa caatataatt attaaaaatg gtattaaacc tccaataaaa
    23461 cttaataatg gtaagtaaaa gtacaattgt ggaataaaca acatacaaag tgctctcatt
    23521 ataagtgcac ctgaagaaac gccaatgata ttcgcctctg ccaaaggatt ttgtagtgct
    23581 gcttgtaata atgctccaga aactgctaac attgcgccaa ccattaatgc aattaatata
    23641 cgtggcaatc gcaaatcaat gattgaatcc actgcttcat tgctaccagt tgtaaatttt
    23701 gtaaataggt cattaaatga caatttaatt gtaccggtta caaacgaaat ataagcagtt
    23761 gcgattaaaa tgactaacaa acataaaaat agtagtttct ttttattttt tatcatcata
    23821 tcaactcact attttttatc cttataaaat aaatcatata attgagtcat tgccttatca
    23881 gcatcaacat ttgctgtaat accgaatggc acttcctcta agtcataaac atgattattt
    23941 ttcacagctt taaaatgttt ccaaatatca ttttgtttaa attctttttg aaacattttc
    24001 ttaacttctt caggcattcc gtgtggtaat cgtaaaataa tatctggatt tatattcaac
    24061 aaattttcag tattagacga aatatattga cgatctttca ctttaataac attttctcca
    24121 cctgctattt taactaaatc accaatatat gatttatcag ttgctactaa atagctacca
    24181 ggtacaccca ttaatattaa tactttggga tgtttctttt gtttagctgc tttattttca
    24241 attttttgct ttacagaatt taaatggtca tttaattctt ttgcttgtgc tttacgatca
    24301 aattgatcac ctaattgtgt aatcgacttt tgcatccctt ttaaactatc aaaatcataa
    24361 aagtagcctt tcatatttaa ttgtttgtaa aatggttgca tttcatcttt aatcgttgac
    24421 acactcaaaa catgtgttgg ttttaacttt ttaacagctt caacattcgg ctccattggt
    24481 tgaccaattt ccggtacatc tttatagcga ttaggcaatg tcttatatga cgtgggtttg
    24541 ccgacaattg gtaaatccaa tttgtccaat gtcattgtca atgcgacagt tgttggtacg
    24601 attctgaatt cgccggattt agttgattct tgagaactgg aagattgaca gctggttaag
    24661 ataacgacgc ttatcactaa aatggttaaa tactttatga ttctcaaact tggttacctc
    24721 tctttctgct gtataaatgt gccgaaataa gtaaaatggt tgctaacaca atgccagctg
    24781 caaataacat atattgcttt ttatgatttg gttcatcaag ttctttaata tcactagata
    24841 attgactact attcttgcta tcatcatctc tattaaaagc tggtaacgct ttttcttttt
    24901 caactacttt tttcttttcc ttttttgatt tttcatcttt atgtttcggt tgctctttgt
    24961 gattattttc aacctttttt actgttgaag gattattttc aacttttaat gtacctgatg
    25021 ctttaggtcg ctcattttca atctttttat tactgtcttg ttgcacttta tctttttgta
    25081 caggaatatc atttaagcct ttttcagtaa aaaggctagt acgtctttcc ttaatgtctg
    25141 atttttgact atcttttttg tcatcaatat cttttttaag ctgatcttga ttattttctt
    25201 gactttgatg ttttgaaggc acttcttttg catcatcatg ttgtactttt ttctctttaa
    25261 aatgaataga atacaccatt tctttgttat ctagattttt cttttcagcc aacgttttaa
    25321 catgcatatt gattttatcc atatgctgtt caattaaaat tcttactatt gtgtcatcct
    25381 tttcatcttt tataacaaaa ggaaattctt catttttgtc attttgaaaa acaagttgtt
    25441 ctttatcaat ttgacctttt agctttactt gcaagtaaat tttaccagtc atatctgaaa
    25501 tcaattgcgc cttttcgtca actagttgtt gttcctcagt tacattttta ttttcttgat
    25561 taaaaattac taactctaac gctttattct cttttatctt ttcatcaaaa attgatgtag
    25621 ttaattctgt tttatctttt gcttcaggtt gattaaattt ggctgatgga tattttatct
    25681 catcagccaa cacgctacca atcattgttg tatatgtaag tatacctaag ctaataatag
    25741 ctataataga ttttgtagca atttgtttaa catttctcat tattccacat tgcctttaga
    25801 tttttttcta acaaacaatg tgattgcgat taataatgct aaggatgcaa ctggtattgc
    25861 atatatatat gcaggtgtac cagcatttgt ttgtggattt tctactttgt ctttattcga
    25921 actgttagat tcactttgac cagtagtcgt tccatcagat cctttgtcac tacctgaagc
    25981 agaattttta tcatctttac ctggtgcatt agcacctgct acatcagttg gtccattaaa
    26041 tttatatgta atgttgtaat gatggtcata tttgaatggc ttaccattta ctttttcatc
    26101 gatataaacg tcaatttttc catctatttt accgttcaac ttacttactt caaattcaga
    26161 agtgcgttca tctttggcag tgtttttact aataatattt tctttatgtc cttcgatact
    26221 cattccagta atccaatgac tgtggttgac agttatttga acatacaatt taccattttt
    26281 cttaatgtac tttgccggtt tattaaaata gtcattagca attgacgtgt cattggtatt
    26341 gtatttgtaa acctcataat tcaaagtacc gctatctgcg gcatttgcag aattactgaa
    26401 tgtcgcgatg atgataatta acgctaaaat cgttgtatta aaaactttta aaatattttt
    26461 caaaacataa tcctcctttt tatgattgct tttaagtctt tactaaaatc ataaataata
    26521 atgattatca ttgtcaatat ttattttata atcaatttat tattgttata cgaaaataga
    26581 tgtgctagta taattgataa ccattatcaa ttgcaatggt taatcatctc atataacaac
    26641 acataatttg tatccttagg aggaaaacaa catgacaaaa cattatttaa acagtaagta
    26701 tcaatcagaa caacgttcat cagctatgaa aaagattaca atgggtacag catctatcat
    26761 tttaggttcc cttgtataca taggcgcaga cagccaacaa gtcaatgcgg caacagaagc
    26821 tacgaacgca actaataatc aaagcacaca agtttctcaa gcaacatcac aaccaattaa
    26881 tttccaagtg caaaaagatg gctcttcaga gaagtcacac atggatgact atatgcaaca
    26941 ccctggtaaa gtaattaaac aaaataataa atattatttc caaaccgtgt taaacaatgc
    27001 atcattctgg aaagaataca aattttacaa tgcaaacaat caagaattag caacaactgt
    27061 tgttaacgat aataaaaaag cggatactag aacaatcaat gttgcagttg aacctggata
    27121 taagagctta actactaaag tacatattgt cgtgccacaa attaattaca atcatagata
    27181 tactacgcat ttggaatttg aaaaagcaat tcctacatta gctgacgcag caaaaccaaa
    27241 caatgttaaa ccggttcaac caaaacctgc tcaacctaaa acacctactg agcaaactaa
    27301 accagttcaa cctaaagttg aaaaagttaa acctactgta actacaacaa gcaaagttga
    27361 agacaatcac tctactaaag ttgtaagtac tgatacaaca aaagatcaaa gtcaaacaca
    27421 aagtgctcgt acagtgaaaa caacacaaac agctcaagaa caaaataaag ttcaaacacc
    27481 tgttaaagat gttgcaacag cgaaatctga aagcaacagt caagctgtaa gtgacaataa
    27541 atcacaacaa actaacaaag ttacaaaaca aaacgaaacg cctaaacaag catctaaagc
    27601 taaagaatta ccaaaaactg gtttaacttc agttgataac tttattagca cagttgcctt
    27661 cgcaacactt gcccttttag gttcattatc tttattactt ttcaaaagaa aagaatctaa
    27721 ataaatcatc gtcacactca taacttaata tattttttat tttaaatttt atttaaccta
    27781 tgtcatagat atttcataat ctataacata ggttattttt ttataaaata acgttgcaat
    27841 taactaccat ttcaatgtac aatacaagta atcaattgat aatgattatc agttgataat
    27901 atacaattag gagttgtttc tacaacatga acaaacagca aaaagaattt aaatcatttt
    27961 attcaattag aaagtcatca ctaggcgttg catctgtagc aattagtaca cttttattat
    28021 taatgtcaaa tggcgaagca caagcagctg aagaaacagg tggtacaaat acagaagcac
    28081 aaccaaaaac tgaagcactt gcaagtccaa caacaacaac tgaaaaagct ccagaaacta
    28141 aaccagtagc taatgctgtc tcagtatcta ataaagaagt tgaggcccct acttctgaaa
    28201 caaaagaagc taaagaagtt aaagaagtta aagcccctaa ggaaacaaaa gcagttaaac
    28261 cagcagcaaa agccgataac aatacatatc ctattttgaa tcaggaactt agagaagcga
    28321 ttaaaaaccc tgcaataaaa gataaagatc atagcgcacc aaactctcgt ccaattgatt
    28381 ttgaaatgaa aaaagaaaat ggtgagcaac aattttatca ttatgccagc tctgttaaac
    28441 ctgctagagt tattttcact gattcaaaac cagaaattga attaggatta caatcaggtc
    28501 aattttggag aaaatttgaa gtttatgagg gtgacaaaaa gttgccaatt aaattagtat
    28561 catacgatac tgttaaagat tatgcttaca ttcgcttctc tgtatcaaat ggaacaaaag
    28621 ctgttaaaat tgttagttca acacacttca ataacaaaga agaaaaatac gattacacat
    28681 taatggaatt cgcacaacca atttataaca gtgcagataa attcaaaact gaagaagatt
    28741 ataaagctga aaaattatta gcaccatata aaaaagcgaa aacactagaa agacaagttt
    28801 atgaattaaa taaaattcaa gataaacttc ctgaaaaatt aaaggctgag tacaagaaga
    28861 aattagagga tacaaagaaa gctttagatg agcaagtgaa atcagctatt actgaattcc
    28921 aaaatgtaca accaacaaat gaaaaaatga ctgatttaca agatacaaaa tatgttgttt
    28981 atgaaagtgt tgagaataac gaatctatga tggatacttt tgttaaacac cctattaaaa
    29041 caggtatgct taacggcaaa aaatatatgg tcatggaaac tactaatgac gattactgga
    29101 aagatttcat ggttgaaggc caacgtgtta gaactataag caaagatgct ataaataata
    29161 ctagaacaat tattttccca tatgttgaag gtaaaactct atatgatgct atcgttaaag
    29221 ttcacgtaaa aacgattgat tatgatggac aataccatgt cagaatcgtt gataaagaag
    29281 catttacaaa agccaatacc gataaatcta acaaaaaaga acaacaagat aactcagcta
    29341 agaaggaagc tactccagct acgcctagca aaccaacacc atcacctgtt gaaaaagaat
    29401 cacaaaaaca agacagccaa aaagatgaca ataaacaatt accaagtgtt gaaaaagaaa
    29461 atgacgcatc tagtgagtca ggtaaagaca aaacgcctgc tacaaaacca gctaaaggtg
    29521 aagtagaatc aagtagtaca actccaacta aggtagtatc tacgactcaa aatgttgcaa
    29581 aaccaacaac tgcttcatca aaaacaacaa aagatgttgt tcaaacttca gcaggttcta
    29641 gcgaagcaaa agatagtgct ccattacaaa aagcaaacat taaaaacaca aatgatggac
    29701 acactcaaag ccaaaacaat aaaaatacac aagaaaataa agcaaaatca ttaccacaaa
    29761 ctggtgaaga atcaaataaa gatatgacat taccattaat ggcattatta gctttaagta
    29821 gcatcgttgc attcgtatta cctagaaaac gtaaaaacta ataaatcgtc tttatattta
    29881 attattaaat taacaaattt taattgacgg atgaggtatc cagttacctc gttcgccaat
    29941 tatttttcgc aatataaaaa gtcccactta aaacaatcat tttaagcggg actttttata
    30001 ttgagtaact aaaattattt agctgctact tcttcgccat tgtaagaacc acagttttta
    30061 catacacggt gtgataattt gtattcgcca cagtttgggc attcagtcat acctggtact
    30121 gaaattttga aatgcgtacg acgtttgttt tttctagttt tagaagttct tctttttggt
    30181 actgccatga tatatcctcc ttagattata aacgaaaaat actaaatgtt agtttaatta
    30241 acaacattat atcattaatt aaactactta ttgctcttta tcatataatt gttgtaattt
    30301 ttgaagcctt ggatcaactt gtcgtgattc tgaatcatct tgttcttgct gtttagcaag
    30361 ctcatctaat tgatcctcat cgattacttc ccaaccatta cctactgtca acatttggtc
    30421 actttgctct gaataagctc tcattggttt ctcaataata actatatcct cgacaatatc
    30481 ctgaagatta accataccat ctttaataat gtgatagtgt tcatctacat catcttgatc
    30541 atcgttatac tgattgtacc cttctaaatc aaatacttct gtagtagtta catctagtgg
    30601 gactttaact ggtacaagag tacgtgcaca aggcattgta tacgttccag taatgtgaat
    30661 atccgcaacg acttctgttg acttaatggt taactgacct tggattgtaa ttggagataa
    30721 atcaattaaa tctaatgatt cttttaaatt gtcaaaactc accgtttgat caaattcaaa
    30781 tggcttacct tgatatttcc ttaattgcgt aattgaccat ttcatatggc ttcacctcta
    30841 acaagcacaa aatttatttt aactttctaa gaacaagttg tcaagatttt ttcttaacat
    30901 atcatgttct gttacaatat taataatgaa taccgaaagg acgaattgca aatgaaaagc
    30961 gttggcttaa tcacagaata taatcccttt cataatgggc atcaatatca tattaatcaa
    31021 tctaaaaaac ttacaaatgc tgacgttact attgcaataa tgagtggtaa ctttgtcatg
    31081 cgtggcgaac cggcaatcta taataagttt actcgtgcaa aaatggcatt atcaacagct
    31141 gatttagtta tcgaactacc agcaactgcc agtttatcat ctggcgatca ttttgccgaa
    31201 ctagcagtta aagtcgcaga ttatatgagt gtcgatacaa ttgcatttgg tagtgaaaat
    31261 aatgatatca aaacattaaa gcaattagct cacagcatta atgaaattga acaatccgaa
    31321 tccttttcac aaaaagtaaa agaaggtaaa agctaccctc gtatcattag cgaattatta
    31381 gagcatcatg aagcactaga aagtcctaac aacatacttg gtattagtta tctgaaagca
    31441 attgctaaac atgctaaaaa catcaatgca atttctatta aacgagaaaa tgctcaacat
    31501 catgattcat taattcaaca ccatcagttt gcaagtggta catctattag aacatcaatc
    31561 attagtcaag atgatcattg gcatcatgtg gtacctaaag atattcaaca cctgtacgta
    31621 acacctcata ttacattaaa tcaaatattt ccatatttga aatatcaaat catagctatg
    31681 actacagagt cattaaaaaa tatttatact gttactgaag gttttgaaaa tcgtttgaaa
    31741 tctaacattt atgaagcaac tgattttcat cattttataa aattactaaa aacaaagcgt
    31801 tatacatata cgcatatcca aagactgtta atgaatgtat tattaaacat taaacctaca
    31861 gatattacga gaaacattca cgcagttaaa gtattagcga tgaacgaccg tggcagacaa
    31921 tatttaaagc atttaaaaac agcgttccca gaaagacaat atataaccaa tattaacaaa
    31981 agcaatgcac attacttcac aaatgaaatc aaagcaacac acatatacaa tgcaataagc
    32041 gggcaacaac aaacagattt caacacgcct gtcatacagc aatatcgtta acaaatgaaa
    32101 acagtatttt aggattgtaa accatgataa acctaaaata ctgttatttt tattacttaa
    32161 atttcttctt caatgccttt tcaacataag gtggaacgaa ttcagaaata tctgctcgat
    32221 aagctgcaac ttctttaaca atacttgaac ttataaatga ataattagta ctagacatca
    32281 tatataacgt ttcaatttca ttgttcaact ttttattcat tgaagttaag cgtaattcat
    32341 attcaaaatc actgactgct cttaaaccac gtatgattgt tttagctcct acttgttcac
    32401 aataatcgac tagtaaacca ctaaattgat gaaccttgac attaggtaaa tgtttaacag
    32461 attgttcaat taaatccata cgctcttcta aactaaacgt accttctttt ttactatttt
    32521 taagaacaca gacatgaatt tcatcaaatc tatctgtact tctctcaata atgtctaaat
    32581 gaccataagt aatggggtca aaactacccg gaatgaccgc tattgtatgt tccatgctat
    32641 tctccctttt ctaataacaa tgtgtctgtc aacccataat ggtaacgttt aatcatatta
    32701 aacggttgat agtctatttc ttcatgattg ctaaattcac aaacgatgat accattttct
    32761 ttcaataaat taaactctga aattagtttt aaagctttat caatgagacc tttattataa
    32821 ggtggatcta agaaaatgac atcaaattga atatcacgtt ttgacaatgc ttttaaagct
    32881 ctatctgcat tatttttata aacttcagat tgcgcctcta aatccaaatt cgcaagattt
    32941 gatttaataa cttttacagc tttaaaattc tgatcaacaa agataacctt atccatacct
    33001 cgagagagtg cttctattcc aagcgccccg cttcctgcaa ataaatctaa acctatacct
    33061 gacacatcat ataaactatt aaagatgcct tctttaactt tatccatagt tggtctcgta
    33121 ttacggcctt ccatactttc taaagcttta cttttatgtt tacctgcaat gacgcgcatg
    33181 ttgttcacac ttccaattca tttagttatt taatataatt tattgagaaa aaggagaatg
    33241 ataaaccaat gaaacaaaca tttattacac taggtgaagg tctaacagat ttgttcgaat
    33301 tcatgacgat gattgaatat aaccatcaac gtattgataa aattatctat tttcattcac
    33361 cacaagctga aaataaaaag tcatctgtag caatcattat gaatcctaca actggcaatc
    33421 atttccaagc attttatatc atgataaacg ctattaaata tccatatcca gattcaaata
    33481 aaaagtttca aatgattaat gattgtgctg aaaaattcga catacctatt ttaggtatcg
    33541 atgtacagcc ccctcaagca tttcatgatt tatcgttata ttataattat ttaattagtg
    33601 tgttaaggct ccaaaaatgg ataccagaac ttcaataata ttaattgtat atttcgtgtt
    33661 tctctttttc gtaagttttc tttaagtatt tatatggtga gccatcaatg tgtctaacgt
    33721 atttaagttg cattagttta tgtacaattt gatcaacatc ttgctcattc acatacataa
    33781 ttacaaattt acgatctcta tttgaatgaa cgatatgtcc atattttcgg atttgtcgtt
    33841 catgtttcat atgttttaaa taaactacaa tactagttct tgggattaaa ttcatttaaa
    33901 cctcactcca tttattttca gcattaatca tatcatgtct ttattaattt taaaatatta
    33961 agctacctta attatgtctt atgtaattgc tcgataaatg tatttagatt atattaaaca
    34021 tcattatatt aattcaattc tcaagaacac cactatatga ttaaccacac atttcgctgt
    34081 agtcagaact atgaatttgt taagctataa aagtaaacga ggaggaattt tttatgaaaa
    34141 aagtaaacag aaacatttta aatgcggtac tagtcggtgc tggatttgta agtagtttat
    34201 taatgataaa taaaaataaa gtgattacta aaaagcaaac catccctgct tttttcaaag
    34261 gcaatgcacc atatatattt gcgcatcgcg gtggtatggc tttaagacca gagcaaacgc
    34321 aacttgcatt tgactatgct aaacaattag gcgttgatgg ctttgaaaca gatgtgagac
    34381 tcacaaaaga tcaacagctt atcgtttttc atgacgcaac tgttgataga acgacgaatg
    34441 gctctggaaa agttagtgcc catacattag cagaattaaa gaaattagac gcagcttatc
    34501 acttcaaaga tatcaatgga caaacaccat atcgtggtca tgcacacaca gctatactaa
    34561 ccttcgatga gttgctgaag caatatcctg atatgtatat aaacgtagac ttaaaagatg
    34621 ctcctgaatc ctatgaaggt tctatcgcac cacaaattat gtttgataca attgcagaga
    34681 atcaagcatt tgaccgcgtt cttgtgacaa gtttttataa agaacaaatc gtccgtttta
    34741 ataaaattgc acaaggatcc gttgcaattg gtgctagcca acaggaagtt acagaggcat
    34801 ttttaaaata tcatttatta ggtggcaggt actaccaacc attagcacaa acgttccaaa
    34861 tgcctactca ttttaaaggc attgatttga cttcatctcg ttttatcaaa tggttaaatg
    34921 atatgaatgt cattccaggc tattatggcg taaatagtat agatctgatg aatgatttat
    34981 accaaaaagg tgcacacatg attgtgacag atcgaccaga tttagcacaa caattcaaac
    35041 aaacaatccc gaaaaaataa aaacatcgag tcagatgcta gttagtggtt tcaataacca
    35101 tctttttctg actcgatgtt ttttataatg aacaattaca ggatccgccc gtcgtacaac
    35161 cactatgtga tgtttgaaag aatggattac ctgtttctat tttgacatgc tctgaaacag
    35221 cgtacgcaat tttcgtaaca acttcatcaa ttaaatgttg aagtgccatt tccctagctt
    35281 tataatgcat cacaacgtca agcatctcat atgctctttt gcgttgtctt gtctctaaca
    35341 taactttctt ataatcagga tgatatttcc cgaatcgcat tacttcatca tatttctctt
    35401 ttgattttaa aaatgattga taaagtaaat gtgcttcgtc attgttttcg agcgcctgtt
    35461 tagcttgctc aaatgatgca taaatatctg atgcaactat catatcagct agttcatcaa
    35521 tatcatctaa tatcgctagt gaagcttcat taatcataaa tacccctcat tgttattttt
    35581 ctaagaaaat tagtgaataa taatctctca ttacatctcc acccatctca tcgtattttg
    35641 aatttaatag acgagatcga tgtatatctg aattcatcca actatggatt aatgttggta
    35701 catcattaaa cgcataacca acattttgag cagttgtttt ataagtaacg tgatttttat
    35761 ctaattgccc tcttaatgcg tcctctgtaa attcaacact atcagaacca ttagaggtcg
    35821 cttcatataa gttattagat gcaatatgtg ctaaatcgct attgattttc aatggtttta
    35881 atccttttaa ttttctcatt tcattcgtta cttcataaag agaaattaat tgatttggat
    35941 tttgctcaac tggacgctta ttatgctctt ctgacgtaga attagaattt aattgataag
    36001 gttcaatatc tgctaacatt tcttttgtta aaaatcgtac acttagcacc tttttcgatt
    36061 gttgatcaga atacacttgt gcatatatgt cgccatattt aatcagtgtt tgtgttttta
    36121 aatcttcatc tgaaagttca aattcatatt ttttaccatc aactttaaag gacggttctg
    36181 gattaatact tgtatgatta aaaatttctg cagaatgttg tcctattttt aacggactaa
    36241 cattgacttt ctcacctgta gcatacactg aaacgatttc ttcacgttta gttgaaacaa
    36301 tgtaataact gtttttgtct ttaaacacat aatttttgta accatctcta aaagggtaga
    36361 cacgatctgc ttgtccaaat ttagaagtaa gcactttaat atttttacct acccatgtac
    36421 caacaccttc tttaggcttt ggattttcag catggttatt tgatttattc acctgttcag
    36481 atctatttac tttattacct ttattcgggt tctctaatac atcaaatttt aatctcggtg
    36541 aataaaaaag atatattaaa aatccaatta aaaataatac accgacgact cttataatta
    36601 actttttcat caatcaacca cctaaaaagt attaatacta ttgtaaaaaa caacacatta
    36661 attagcaaat tttcaacact gacataactg tgtcgtttcg ataaaacaaa atcatcttca
    36721 ggcataattt taacgtcata aagattttcc ctacactcta tatcataacc tatctttatg
    36781 ttttcaggtt gaatttcatt attaagatta aaatatgtat aaaaaaatgg acagttaagg
    36841 tatcaaatga ataccatcaa ctgtccgact attcttcatc aaaaaacctg ataaaacaaa
    36901 ttgccttatc agattagtat catttgtata agcatattaa tgaccaaatg ttgctttaat
    36961 cagtgatgtc gtttctccac ctggatataa tacatataat aataagtaaa ctgctacacc
    37021 tgtaattgca gtacagaacc atataactga agcgaatggc ccgaatttgc ggtgtacatt
    37081 atatttatct ttaaatgcag taataatttg aactagacct agaataccac caattgttgc
    37141 taaattaatg tggaaaaata agaaaatcgt ataatatttc ttaattgatg ctggtccgcc
    37201 aaatgctgta ttaccgataa aaatcgttct acttgcatag attaagaaaa aagttaaagc
    37261 aaaaacagct gcagctaaca taacattttt gtgtttattt atttcccttt tccaaataag
    37321 tctccaacca atggcaatta aaattgcact aatgacaata catgtcgtac taatcgttgg
    37381 taaaattgga acgcccatat ttttcatcct aacttaatta atctagatca aagtaagtaa
    37441 tgaaacaatc acagctaaca cgaaaaagat cactaaataa tttagtgaat atataaacat
    37501 ttgtgttgcc cattttgttt gatctgaatt tttcttaaat gttgttaaac ctaatgcaat
    37561 ccatcctaaa tttaataatg tagctaacac tacgaatacg acacctaaat ttattagtaa
    37621 taaaggtact ggcaataaaa taatcaacca gataaacata ctgacacgtg tacgtttaaa
    37681 gcccttaact gatggtaaca ttggaatatt tgcaagtgca tattcatctt tacgtttaat
    37741 agctaaggca taaaaatgaa ttggttgcca acaaaataca actaaaaaca gcgcaatcgc
    37801 tgttaaacta atttgtcctt caattgcaac ccatccaatt agtggtggta ctgctccagg
    37861 aaaactccca atcactgtgt tccatgttgt atgtctttta gaccatattg agtaataaga
    37921 cacataacct acaatcccca taagaccaag tacgcctgat ggtatattca ataaaaacaa
    37981 acaaatttct ccaactaaca tcataccaaa acttaatagt aataaatttt gatctgtaat
    38041 tctattattt acagttggtc tattttgttt actaggcata atacgatcaa tatcttggtc
    38101 gtaataatta tttaacgcac atgcgccacc cataattaaa gtagatccta atagcattaa
    38161 taaaatttga ggtattgatg ataagaagga atgatttgtc attacaactg ctagccatgc
    38221 gcccgcaaaa gccggaatta agttaccttg aacaagtccc attttaatta tctgttgcaa
    38281 ttctttgaag ttaactctgc taatattttg tgacaaagta tgctctttgc tcataatccc
    38341 cctccttaaa tttgttcata taagattatg atatcttaga ttgcataaaa agactaggtt
    38401 taataaaatt aaaatgtgac aaattaacga caagagaaaa tgtcaatttt gtgacacaaa
    38461 taacatttaa tttattgcta taatgtatat gttagaaaat tttaataagt agaatcatgc
    38521 atctaaaaga gattaatatt taagcttcaa atttgagtaa acgtggatta cataattatc
    38581 ccaataaaaa atcattacga ttaagttctt tttatgtcgt ccacatacaa tacttgtaaa
    38641 attaaatcat atttcctgcg ttggatccca tcttttcata tcctacaatc aggtcaattt
    38701 atagtatcat ctcaaatccg gctattaatt ctaattctca gtgatgcgtt tttttatgat
    38761 ggggtgtata aattgtttgg caaaaagaat ttaaaatggt taggtgtcgt agcaacgtta
    38821 atgatgacat ttgtacaact tggtggagcc ttagttacca aaaccggatc agctgatggt
    38881 tgtggttctt cttggccact atgtcatggt gcgttgattc cagaattctt tcctattgat
    38941 acgattattg agttaagtca tagagccgtt tcagctttgt ctttattaat ggtcttatgg
    39001 ttagttatca ctgcatggaa acatataggc tatattaaag aaattaaacc tttatcaatc
    39061 attagtgttg gattcttatt attgcaagca ttaatcggag ctgccgctgt tatttggcaa
    39121 caaaacgatt acgttttagc attgcacttt ggtatatcat taatcagttt ctcatctgta
    39181 tttttaataa cattgattat tttctctata gatcaaaaat atgaagctga cgaattatat
    39241 atcaaaaagc cattaagacg tttaacatgg ttaatggcaa tcatcattta ttgtggtgtt
    39301 tatactggtg cactagtgag acatgcggat gcaagtttag catatggtgg ttggccattg
    39361 ccattccacg atcttgtacc acattcagaa caagattggg ttcaactcac gcatcgtatc
    39421 atggctttta tagtgtttac gattattatg attacttata ttcacgctgt taaaaattat
    39481 ccaaataacc gtactgttca ttatggttat acagctgcat ttatacttgt tatattacaa
    39541 gttatcacag gtgcattatc tattatgaca aatgttaacc tgataatcgc acttttccat
    39601 gcattattta tcacttattt atttggtatg acaacatact ttatcatgct aatgttacga
    39661 tcagtaagaa gtgacaagca ataacaaaaa agcaaaccgt aattttaatg gcacgcccat
    39721 taaaattacg gttttttata tcaatattta aaattaaacc taagacatgt aaaaacgaga
    39781 ttacacgtca attgttgtgt aatctcgttt tattttaatc attttagtca gttgcttttt
    39841 caatttcgat taataaatcg cctgtcgcta ttgtgtcacc attatttaca gttacttgtt
    39901 taatcacacc gtcaaatggt gcttgaattg ttgtttccat tttcatagct tcagtaatta
    39961 gcaacggctg gttagctttc acagattcac ctacactaac cttgacttca gttactgaac
    40021 ctggcatttg cgcacctata tgacttggat tactcttatc tgcttttggt ttaacgttcg
    40081 catttgtatg tacattttca tctttaatgt aaatacgtct cgcttgacca ttcatcgcat
    40141 agtaaatcgt tctattacca ttttcatctg gttcactaat cgtttctagt ttaataatta
    40201 atcgtttacc tttatcgatt tcgatttcta ctgtttcacc attacgcatt ccaaagaaga
    40261 atgtaggcgt atcaagtaac gataagtttc cgtattgatt tctagtttga atatattgtt
    40321 catatacttt tggatatagt acataactaa taatatcttg ctccgtaaca ggaccttgtt
    40381 gctcttcttc aagcaactca cggacttttt caaaatcaac cggctctaga tattcacctg
    40441 gacgagctgt tagtgcttct tggcctttta aaataaccgc ttgtaaatct ttattaaaac
    40501 catttacagg ttgtcctatt tcgcctttga agaacgacac tactgattct gggaaatcta
    40561 atttatagcc atctgtaatc acggattgtt catcaagatc attttgtacc atataaagtg
    40621 ccatatcacc aactacttta gacgatggtg ttacttttac gatatcacca aataagaaat
    40681 tcactctgcg atacatatct ttaacttcat caaatctttc gcctaaacct aaacttttag
    40741 cttgttggct taaattcgaa tactgtccac caggcatttc atgttgataa atttcagtat
    40801 tcggtgattt gatatcactt tcaaagtctg aataataagt acgtacagtt gaccaataat
    40861 gactaagtga ctccatacct tcaatatcag ttctaaggtg gcgtgggaag ccattcaatg
    40921 cataatataa cgaattggcg cttggctgac ttgttaaacc actcattgaa gcaacagcag
    40981 tatcaatgat atcgacacca gcatctattg cttgtttgta tgttaataaa ccattaccac
    41041 ttgtatcatg agtgtgaaga tgaattggta aatctacagc tgattttaac tcaccaatca
    41101 attcgtaagc ggctttaggt tttaataagc ctgccatatc tttaatcgct aaaatatgga
    41161 aaccttcacg ttctaactct ttagctagtt tgacataata ctctaaagta taaatgtttg
    41221 atcgctcagg atttaaaatg tcacctgtat aacaaatagt accttcagag attttgcccg
    41281 cttcttgtac tgcttcattg gcaactttca tttgatctac ccagtttaat gaatcgaaaa
    41341 ttctaaagac atctatgcct gctttagcac tttcttgtac gaatttatga ataacattat
    41401 caggatagtt tttataacca actgcgtttg aagcacgtaa caacatttgg aataatacat
    41461 ttggaatagc tttacgtaga cgttcaagtc gttcccatgg gttttccttc aagaaattat
    41521 atgccacatc aaatgtagca ccgccccaca tttctagtga gaaaccatct ttaaatacgt
    41581 ccgctgtttt ggatgcgata ttaatcatat ccttagttct aactcgtgta gctaataatg
    41641 attggtgtgc atctctaaaa gttgtatctg ttagtaagac atcatcctgc tttttaaccc
    41701 attcagctac accttttgga cctacttcat caagcaattg tttcgtacca ctaaatgaag
    41761 cgattttact tgaagataca gttggaattg atgctaattc atagtctggt ttcggacgtt
    41821 tctcaacatt tgggaaacca ttaattgtta cattacctat atattctaat gttttagtac
    41881 ctctatctag agacggctga atgtcgaaaa gttctggtgt ttcttcaata aatttagttg
    41941 tgtaatcacc acttgtgaac tttttattct tcattacatt aattaagaat ggaatattag
    42001 ttttaacacc acgaatacgc atttctcgta atgaacgtac cattttttct tctgcttgtt
    42061 taaatgatat cgcgtgtgta gataatttta cgagtaatga atcataataa ggtgatatct
    42121 cagcaccttg gaaaccatct ccagcatcaa gacgtacacc aaagccaccg cttgaacgat
    42181 aagcaatgat tgttccagta tccggcatga aatcatttaa cggatcttct gttgtaatac
    42241 gacattggat ggcatagccc aatgttgtaa tatctttttg ttgcggcata ttaatttctt
    42301 caccaaataa atcggcacct gctgcaacta aaatttgtgt cttaacaata tcaattcctg
    42361 ttaccatctc tgtaattgta tgctctactt gtacacgagg gttaacttct ataaagaaga
    42421 attcgtcacc agatactaga aattcaacag tacctgcatt gacatattta atattttcca
    42481 tcaattgaat tgcagcatca caaatacgtt gacgtaatgt tggtgataat ccaactgatg
    42541 gtgcaacttc tacaactttt tgatgacgac gttgtactga acaatcacgt tcaaataagt
    42601 gtacgatatt tccatgttcg tcacctataa cttgtacttc aatatgcttt ggattatcaa
    42661 tgtatctttc tatgtaaact tcactattac caaatgattt ttcagcttct gattttgctc
    42721 tatggaaagc atcttctaat tcactttctt cacgaacgat tctcatacct ttaccgccgc
    42781 caccacttgt ggctttaatc attagcggga aaccagcttc ttctgcaaat tcttttgcta
    42841 attcatatga tttaattgga ccgtctgtac caggaataac tggtaaatct gccttgatag
    42901 ccgttgtacg agctttaact ttatctccaa acatatctaa atgttctaaa tgaggaccaa
    42961 taaatttaat tccttcttct gcacaacgac gcgcaaattg ttcattttca cttaaaaatc
    43021 catagccagg atgaatcgca tccacattcg cttgttttgc tacatcaatg atacgctcaa
    43081 tatttaaata actttcagca ggacctaaat cacttccaac taaataggat tcatctgctt
    43141 tatatctatg taatgaactt ttgtcttcat tcgaataaat tgcaactgtg ctgatgtcta
    43201 attctgctgc cgctctgaat atacgaattg caatttctcc acggttagca acaagtaact
    43261 tttttatttg tttcaatagc gatacactcc tcaaactatt agaattttct aactaattag
    43321 ataataaaat tttatcttaa agcgctctgt tttgctatag ttatgtttca aattttcaaa
    43381 atttaacatt cttgagacaa ttaaaacctc cgcttcaaaa ataataattt caaaaatgac
    43441 tatgcaacaa caggtagttc acgtttttgt tgtgaaacat tttcgatttc tacaactcta
    43501 aaaaattaaa aataaaattg caaaacatca acatttatta tcaatagcga taactttatc
    43561 ttatcatcat gattctaatt tcgccaccac atttagtaat ttttagtcat aaaatttagt
    43621 tataattata cgttgtttcg tttataaaat ttgataatca tgagtaatct cgtaatatca
    43681 aaacaaaaag gaagttaagc gttgtttggt tgcctaactt ccgttattta actcatcagt
    43741 ccaatttaac aaagagtata taaatagcca atgtttagca tcgatttatg acagaagtca
    43801 tctcgtacta aatattggct agtatttttt aattaaattg tcttcttata tcaacttttt
    43861 gttgttgttt ctttcgttgc tggtctactt tgatttgttt acctacaatc agaagtaatc
    43921 ccatagcaat acttaaacta atcattgatg atccaccaaa actgataaat ggcaatggca
    43981 caccagttaa tggaattgtt gccgaaatac cgccaatgtt tacaaacgtt tggcttccaa
    44041 agtatgtggc aatcccaaca cacacaagtt tataaaaata tgatgatgtt ttatttgcaa
    44101 actgaaaggc acgatataca ataaagaact ctaaagtaat aactagcaat cctccgatta
    44161 aacctaattc ttcgcaaata attgcaaaaa taaaatctgt atgtggttct ggtaaatagc
    44221 ccaatttcat tgcactattt cctaatcctt ttccaaatac gccaccgtta cctatcgcaa
    44281 gcaatgaatt ggaaatatgg tatccagttc ctgattcgaa ttggaatgga tctgttagcg
    44341 tactaaatct ggctgttaaa taacttggta accaaccagc cattaatgca atgacaaata
    44401 ctactaagaa tcctagcact gctggtatac caaatcttag gactttgttt accccaattc
    44461 ctgaataaaa aatgatcgca actaaaataa ttaatattag taatgtttgc cctacgtctt
    44521 tttgtaggaa aactaaaaac gtacaaccta atgctaatac aataggactt aaaattaatt
    44581 ttggtttact taatactcta ggcatttttt tactgatcat aaatgggata tataatatga
    44641 ttgcaatttt taataactca gatgcctgta agttcataaa tcctaagttt atccaacttt
    44701 tagaaccatt aatatcttta ccgattacta acgtcagtaa taatagcgag acgatagtta
    44761 taatcatacc tttttgcact ttaatattac tcagtaattt aacattcatt aaaaatgcaa
    44821 taaaaaatac aatcataaaa ctcattatga catatgctaa ttgtcggttg taaaaatacg
    44881 ttcctggaac atcgatacca ccagtcaatg tgcctttagt tgctggaacc atactggcac
    44941 tatataccat cactaatcca attaaactca atacaatata tgtaactaat aacgggtaat
    45001 caataaactt tgaggtttta ccaatatacc gtaaaatact tctaaaattc ttcatatatt
    45061 cagtcatcca attctacaat ttatacttca aatgatttcg ttttatactt taattttaaa
    45121 aatccatgtt acttattata tacatgacat cgtcataatc acaaatatta acaggtatct
    45181 tgaggtaatt tatagaatat ttgtttactt aatatcgtga attgctaaaa cccaataaaa
    45241 gtgactgaca tgtcatcaag aagacaacat aacagccact ttaatcagta attaaactat
    45301 aaatataaaa tcggcgcagc tcaattgtcg atatctcacg ccgttttaat atgcttatat
    45361 attaaacctt aaacaagtgt aaaagcttca tgtaattttg aaagttcttt ctcaagacgt
    45421 aacattattt gtttgccatc ttcgcggtca actaaaccta atttaacagc aaaatcaact
    45481 tctttttgaa gtccaaacat ttgtgtatct agtacttctt catataatgg gcatgaaggt
    45541 aatgttaaat tatctagttg aactttaatc agatgtaaga tttcatcagc atctttagtc
    45601 aattgtttca aagctgcatt tttcattgtt gtttgtttcg ccatgacacg ctccccctct
    45661 atataaattc tcaagtctta ctaaaagttt atcttactaa atattaaaaa gcaagtagat
    45721 ttaaaatgtg tcgttagcaa tttgtgttaa aataatgcta tatacattga tagggagtgg
    45781 gaaaatgata caaattaaag gagccgtaaa gtttcctata acattagata gtacgacttg
    45841 gattttcgat gatagaaaag ttagcatcga agatttagaa aaaggtgtat ttgatggttc
    45901 aaaaccaatc gactttgaag ataatcatga atggaatcgt gctatcctag aaggacaaac
    45961 taatccgcct actttaaatt cagaaataaa atataaaaaa cgtgccatgt tagaaggttc
    46021 atttgtcatt aatatgacac catttttcaa acattccgaa ccacatgact ctgcaactac
    46081 tattcgatta tcaaatgagc atgatcattt agatataccg atagatcttt taccctattt
    46141 atttttccaa tttgcaaaag acggtaaacg actttacagc gataatggtg tagatagttt
    46201 tatttacaat caagaagatg gttattcata tcgaatcaac catgtaactc atattgaggt
    46261 gatttaattt gagacaagtg caatgcatta tctgtgatgc aaaagtattt atagatgagc
    46321 gcacaactga gtctaaacga cttaaaaaca atcctattcg aacatttatg tgcgatgatt
    46381 gtaaaagtcg attagacaca cctaaacaac gtgcgcaaca ctatccgctc gattaatatc
    46441 tgaataaaca agttagaaat ttgaaaatgt gaaagtaaca ggaaataata gcatttaaac
    46501 actttttcaa atattatatg ccaaaagaga agctaagcaa ctttcattgc tcagcttctc
    46561 ttttattatg ttaaattatt cgttttcttg catcatttgt ttgatacgct ttgcttcttt
    46621 ttcacgaaca tttttgttta aaattttctt tcttaaacgt atgctttctg gtgtaacctc
    46681 aacaagttca tcatcattaa tgaattgtaa cgcttcttcc aatgttagaa tacgcggtct
    46741 attcattgtt tgtgtttggt ctttcgttgc agaacgtacg ttagtttgat gttttgtttt
    46801 agtgatgtta acagttaaat cattttcacg attatgttca ccaacaatca taccttcata
    46861 aacttcagta ccaggttcca tgaagtttac acctctatct tcaagtccta aaatggcata
    46921 agtacttgca gaaccttgat ccattgaaat taatgcacca ttacgacgac cgccaatttg
    46981 tgctttaata cgtggtctaa attcttcaaa tgtatggtta ataataccgt aacctcttgt
    47041 cattgacata aattcagtcg tataaccaat cataccacga gccggtacat taaagattaa
    47101 acgtgtaagt ccattatcag ttgtagtcat atcaaccatt tcacctttac gtgcacctaa
    47161 tgattcaata accgcacctg cattttcttg tggcacttca cattgcacac gttcaaatgg
    47221 ttcacacatt acaccatcaa tttctttaat aattacttgt ggttttgaaa cttgtaattc
    47281 ataaccttca cgacgcatat tttcaataag gattgataaa tgcaattcac ctcgaccagc
    47341 aactacccat gtatctggag aatctgtgtt agaaactttc aaagatacat ctgtttctaa
    47401 ttgttgattt aaacgttctt gaatttgacg cgctgttaca aagtcacctt cacggccagc
    47461 aaatggtgaa ttgttaactt taaatgtcat ttcaagagta ggctcatcaa tacgtagaac
    47521 tggcaatgct tcttgatggt catgtggtgt tacagtttca ccaacattaa tgtcttccat
    47581 acctgaaaca gcaattaaat ctccagcttg tgcttcttca atttctaaac gttttaatcc
    47641 aaagtaacca aagattttag ttacacggaa gtttttcact gtaccgtcta atttaattag
    47701 tgatacatta tctccgacac gcattttacc tctgaataca cgaccaatac caatacgtcc
    47761 aacataatca ttgtagtcca acaatgctac ttggaattgt aatggctcat cactgttatc
    47821 aattggagct ggtacataat caataattgt ttcatataat gattgtaaat tatcatcttg
    47881 tttttcagga tctaagctag ctgtaccatt tactgctgaa gcataaacaa cagggaattc
    47941 taattgttca tcgtttgctt ctaattcaat aaataaatct aaaacttcat ctacaacacc
    48001 ctctggacgt gctgatggtt tatcaatttt attaacaaca acaacaggtt tcaggttttg
    48061 ttctagcgct tttttaagta caaaacgtgt ttgaggcatt gtaccttcat acgcatctac
    48121 tactaagaca accccatcaa ccattttcat aatacgttct acttctccac caaagtctgc
    48181 atgtcctggt gtatccaaaa tattaatacg tgtaccttta taatcaacag ccgtattttt
    48241 ggctagaatc gtaattccac gctctctttc aatatcgtta gagtccattg cacgttcatc
    48301 gacatgttca ttttctctga atataccaga ttgttttaac aactcatcta ctaaagttgt
    48361 tttaccatgg tcaacgtgag caataattgc tatattgcgg acatcttctc ttttattagt
    48421 catataaata gtttccttct ttcttaagta aaatcccact tttaattaca acttttttat
    48481 tatatcatat aattgagaaa agataagcaa aaggtgggga taggatgaaa caaaaaaaat
    48541 ctaaaaatat cttttgggta ttttctatat tagctgttat tttcttagta ttatttagtt
    48601 ttgctgttgg tgcatcaaat gtaccaatga tgattttaac atttatatta ctcgttgcaa
    48661 cctttggaat tggatttact acaaagaaaa aatatcgaga aaacgattgg ctataagtta
    48721 tatcgacaat aacacgcgtt gattaaagac cacgcatgtt catgatgaac atttaaatgg
    48781 ttttatattg gcgcgtgttt ttattattta agatataaaa gcgtaatatg ttacctaatt
    48841 gttaggacta catattacgc ttttggtaat tattttgatt ttcttttaaa tcgtcgttca
    48901 tgtaattgta ttaacgcatc gcgatgtggc tctaaatata catcgaggat ctctctatga
    48961 acaccacgat taccaactaa aactgagttt ggaccaccaa ttgttagcgg ttcacccaat
    49021 aaatttgaag cttgtccatt tacttcatat aaaataacca atcctccagc aaaatcccac
    49081 ggttggagtc taggtgtcat atatgcttct aaattaccgg tagcaacaga aacaatttca
    49141 agcgctgcac taccatatgc ccttgcactt ctagaatcat taacaatttc tttaaagatt
    49201 tctcctaaaa ttggtttagt taaccagttc ggattgatcc caataatgct ttgtcttaga
    49261 ttagaatcat tcaatggttt caagggttgg ctacctcgat atgcaccttc ccctacttta
    49321 gcatgatata agacatcagc cataacatca tatacaaaac ctgcataagg tttaccatcg
    49381 atataaatac caattgaaat cgcgaaattt tcttgttgat gaacaaaatt caatgtaccg
    49441 tctattgggt caacaaccca taccgtacct ttggaagtat cgatgtcatg accatgccct
    49501 tcttcaccta atacttgatg attgggatat gtttctaaaa ttgtatcaaa aataaaatct
    49561 tctgttgctt tatctacatt tgtaacaagg tcattcggat ttgactttgt ttcaattgtt
    49621 aaattttgct ccatcaattg tttaattcta attcctgctt cttgaataag tccttgggca
    49681 aatccataaa gtgccataac atcatctcct aacatcttta ttatacatca acattttata
    49741 aaaataactt cttatgataa aaatgaaaat actaatttta atgagagcgt cttaagccgc
    49801 aattgataaa acatatgcta caatattttt aaacactata caggaggtac tctatgacaa
    49861 aatatacatt taaacctaaa gatttcaaag cgttcaacgt agaaggttta gacgcacgaa
    49921 tggaagcttt aaacgaatac atacgaccac aactccatga attaggagaa tattttagtg
    49981 acttctttac aagtcaaact ggtgaaacat tttatcctca cgtagcaaaa catgctagaa
    50041 gaagtgtgaa tcctcctaaa gatacatggg ttgcttttgc tacaagcaaa cgaggctata
    50101 aaatgttacc tcatttccaa attggtatgt ttgaagatca actgtttgtt atgtttggaa
    50161 tcatgcatga agcaaaagat aaagcaacac gtgcaaaagt ttttgaaaga aaatttaaag
    50221 ctattcaaca attacctgat gattatcgtg tttgcttaga tcatatgaaa cctgataaac
    50281 catttattaa agatttaacg gatgatgatt taaaagaagc gatacaaaga gccatcaatg
    50341 taaaaaaagg tgaattcttt atagcgcgtg caatcacacc acaagataaa agattaaaaa
    50401 gtgacaaagc atttattgca tttttagaag aaaccttcga tcagttctta ccattttatt
    50461 ctgcataaat aactttgttt aaataataga gcactaaatc acatccatga tttcgtgctc
    50521 ttttttctta atattaaatc gaacgttcaa cataataatt catactttta aaaaaattaa
    50581 aataatttta ggttgaccta aacattttat taggttatta tattgtccat aagaagtaga
    50641 ggtgagtcaa aatgaataat aaacgacatt caacaaatga acaattaagt ttagacgaaa
    50701 taaacaatac aattaaattc gatcatcgca gttcaaataa acagaaattt ttatcatttc
    50761 ttgggcctgg gttattagtc gctgttggtt acatggatcc cggaaactgg ataacatcaa
    50821 tgcaaggtgg cgcgcaatat ggctatactt tgctattcgt aattcttatt tcaagtttat
    50881 cagcaatgtt acttcaaagc atgacagtga gattaggaat agcaacaggt atggacttag
    50941 ctcaaatgac acgacattat ttaccaagac ctattgctat aatcttttgg attattgcag
    51001 aactagcaat tatcgccaca gatattgctg aggttattgg tagtgctatt gctcttaatc
    51061 tcctatttaa cataccttta atcgtcggtg cactaataac tgtacttgat gtatttttac
    51121 tactatttat aatgaaatat ggttttagaa aaattgaagc tattgttggt acattaattt
    51181 tcacagtgtt attcatcttt atatttgaag tctatatttc atcaccacag ttgaacgctg
    51241 tgttaaatgg atttatacca catagtgaaa tcattacaaa taacggcatt ctctatattg
    51301 cattaggtat tattggcgct acaattatgc ctcataattt gtacttacat tcatcaattg
    51361 tacaatctag aacatactca agacataaca atgaagaaaa ggcgcaagcg attaaatttg
    51421 ctacgataga ttcgaacatt cagttatcaa tcgcatttgt agtcaattgc ttattattag
    51481 tgttaggagc atcactattt ttcaactcga acgctgacga tttaggtggt ttctatgatt
    51541 tatatcacgc cttaaaaact gaacctgtac taggtgcaac aatgggtgca atcatgagta
    51601 cattatttgc agttgcatta ttagcgtcag gtcaaaattc aacgattact ggtactttag
    51661 caggacaaat tgtaatggaa ggatttttaa gattgcacat accaaattgg ttaagacgtt
    51721 taattacacg ttcccttgct gtcattcctg ttatcgtatg cttaatcatt tttaaaggta
    51781 atgcagctaa aattgagcaa ctacttgtat tctctcaagt atttttaagt attgctctgc
    51841 cattctgttt aataccatta caattagcta ctagtaataa agacttgatg gggcctttct
    51901 ataataaaac atgggttaat atcatttcat ggacacttat tattattcta agtattttaa
    51961 atgtctattt aatcgttcaa acattccaag aactacaagg ttaaaaataa aaccattaaa
    52021 atgttggttg tatctaataa ttaacaactt aacattttaa tggtttttct tttgctatga
    52081 acatattaat gataaatata ctcatcgtcc ttatgtgtag tttcttttga ttctttttta
    52141 gaaatcaaca taatcatcac gataatccat aagacaattg caattaaatt aagagccatc
    52201 aaacttacaa ttatcgcgat aacaaaaagt ataatcgata attttctacg ccctttaata
    52261 caaattgtcg caaatatacc ataaagtgtt gaaattaata aaataattgc taatgcacca
    52321 attgttgtct gaagcatatc taaagaaaca ttgccaccgt tctgagataa ttgcttcgct
    52381 aattcttcgc gttgtgatgc attaccactt tttaaagaaa aataggatag ccccataact
    52441 aataaataaa taatactaat actatttgca atccaagcca tgattaattc aggttttcta
//
LOCUS       DAPSKH010000010        50268 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPSKH010000010 DAPSKH010000000
VERSION     DAPSKH010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 50268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50268
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.010"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            55..1056
                     /gene="argF"
                     /locus_tag="RPH49_000706"
     CDS             55..1056
                     /gene="argF"
                     /locus_tag="RPH49_000706"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDY5123895.1"
                     /translation="MKNLRNRSFLTLLDFSRQEVEFLLTLSEDLKRAKYIGTEKPMLK
                     NKNIALLFEKDSTRTRCAFEVAAHDQGANVTYLGPTGSQMGKKETTKDTARVLGGMYD
                     GIEYRGFSQRTVETLAEYSGVPVWNGLTDEDHPTQVLADFLTAKEVLKKDYADINFTY
                     VGDGRNNVANALMQGAAIMGMNFHLVCPKELNPTDELLNRCKNIAAENGGNILITDDI
                     DQGVKGSDVIYTDVWVSMGEPDEVWKERLELLKPYQVNKEMMDKTGNPNVIFEHCLPS
                     FHNADTKIGQQIFEKYGIREMEVTDEVFESKASVVFQEAENRMHTIKAVMVATLGEF"
     gene            1079..2011
                     /gene="arcC"
                     /locus_tag="RPH49_000707"
     CDS             1079..2011
                     /gene="arcC"
                     /locus_tag="RPH49_000707"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDY5123896.1"
                     /translation="MAKIVVALGGNALGKSPQEQLELVKNTAKSLVGLITKGHEIVIS
                     HGNGPQVGSINLGLNYAAEHNQGPAFPFAECGAMSQAYIGYQLQESLQNELHSIGMDK
                     QVVTLVTQVEVNENDPAFNNPSKPIGLFYNKEEAEQIQKEKGFIFVEDAGRGYRRVVP
                     SPQPISIIELESIKTLIKNDTLVIAAGGGGIPVIREQHDGFKGIDAVIDKDKTSALLG
                     ANIQCDQLIILTAIDYVYINFNTENQQPLETTNVDELKRYIDENQFAKGSMLPKIEAA
                     ISFIENNPKGSVLITSLNELDAALEGKVGTVIKK"
     gene            2182..3738
                     /locus_tag="RPH49_000708"
     CDS             2182..3738
                     /locus_tag="RPH49_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDY5123897.1"
                     /translation="MENTINESEKKKRFKLKMPGAFMILFILTVVAVIATWVIPAGAY
                     SKLSYEPSSQELKIVNPHNQVKKVPGTQQELDKMGVKIKIEQFKSGAINKPVSIPNTY
                     ERLKQHPAGPEQITSSMVEGTIEAVDIMVFILVLGGLIGVVQASGSFESGLLALTKKT
                     KGHEFMLIVFVSILMIIGGTLCGIEEEAVAFYPILVPIFIALGYDSIVSVGAIFLASS
                     VGSTFSTINPFSVVIASNAAGTTFTDGLYWRIGACIVGAIFVISYLYWYCKKIKKDPK
                     ASYSYEDKDAFEQQWSVLKDDDSAHFTLRKKIILTLFVLPFPIMVWGVMTQGWWFPVM
                     ASAFLIFAIIIMFIAGTGKSGLGEKGTVDAFVNGASSLVGVSLIIGLARGINLVLNEG
                     MISDTILHFSSSLVQHMSGPLFIIVLLFIFFCLGFIVPSSSGLAVLSMPIFAPLADTV
                     GIPRFVIVTTYQFGQYAMLFLAPTGLVMATLQMLNMRYSHWFRFVWPVVAFVLIFGGG
                     VLITQVLIYS"
     gene            4045..4272
                     /locus_tag="RPH49_000709"
     CDS             4045..4272
                     /locus_tag="RPH49_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123898.1"
                     /translation="MTHLTKVLDTLTGICVVLLFSKYFVAYANMVFDWKLRWYLLENI
                     PHLPIILFILMFIFGVPSEMIKDRQRKNNGV"
     gene            complement(4578..5525)
                     /locus_tag="RPH49_000710"
     CDS             complement(4578..5525)
                     /locus_tag="RPH49_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDY5123899.1"
                     /translation="MRLQKAPLVTSGLILGLLGLGNLLKDLSLTLNAVCGIFAFLIWI
                     HLLCTMLKYSNNVKEQLNSPLVSSVFTTFFMSGFLGTTYLNTFFSNITFINSLITPIW
                     ILCLVGIMTHMIIFSIKYLKDFSLENVYPSWTVLFIGIAIAGLTAPVSGYFFIGQLTV
                     IYGFVATCIVLPIVFKRLKAFPLQTSIKPNTSTICAPFSLVAAAYVIAFPKANAFIVI
                     IFLILAQIFYFYIIIQLPKLLKEPFSPVFSAFTFPLVISATALKNSLPVLMFPDIWKG
                     LLFIEVLLATVIVLRVFIGYLHFFLKKENQDKFLRNASQ"
     gene            5774..5962
                     /locus_tag="RPH49_000711"
     CDS             5774..5962
                     /locus_tag="RPH49_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDY5123900.1"
                     /translation="MRNQIQKLLDSDLSSLHISKQTGVPQSTIHRMRKKERSLDNMSL
                     KNAELLYKFANSIFSNEN"
     gene            complement(6431..6504)
                     /locus_tag="RPH49_000712"
     tRNA            complement(6431..6504)
                     /locus_tag="RPH49_000712"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6468..6470),aa:Arg,seq:tct)
     gene            6868..7002
                     /locus_tag="RPH49_000713"
     CDS             6868..7002
                     /locus_tag="RPH49_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="HDY5123901.1"
                     /translation="MEGLFNAIKDTVTAAINNDGAKLGTSIVSIVENGVGLLGKLFGF
                     "
     gene            7059..7193
                     /locus_tag="RPH49_000714"
     CDS             7059..7193
                     /locus_tag="RPH49_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-class phenol-soluble modulin"
                     /protein_id="HDY5123902.1"
                     /translation="MTGLAEAIANTVQAAQQHDSVKLGTSIVDIVANGVGLLGKLFGF
                     "
     gene            7317..7955
                     /locus_tag="RPH49_000715"
     CDS             7317..7955
                     /locus_tag="RPH49_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDY5123903.1"
                     /translation="MGKLGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDF
                     LTFKKINHQHWEAFQQNKLTKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKV
                     KYFDQTLETIVELSKRHDLYIVTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPN
                     PEFFNYVFNDIGEDERQHSIIVGDSLTSDILGGINAGIATCWFNFRGFDHNP"
     gene            complement(8118..8558)
                     /locus_tag="RPH49_000716"
     CDS             complement(8118..8558)
                     /locus_tag="RPH49_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDY5123904.1"
                     /translation="MSEIKRLEINYKTDELFENFRAFGNKDLYMVNELNGQMIDASSD
                     SPFYGIFVGDQLGARMALLKKGDVEEIYFPDFEDYILLWKLEVLPKYQNRGYASELID
                     FAKSFNMPIKAIGRNDSKDFFLHHGFTDVEAKNIEGHDVLLWKP"
     gene            8753..10366
                     /gene="bshC"
                     /locus_tag="RPH49_000717"
     CDS             8753..10366
                     /gene="bshC"
                     /locus_tag="RPH49_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol biosynthesis cysteine-adding enzyme
                     BshC"
                     /protein_id="HDY5123905.1"
                     /translation="MDCKVVSLNEKDQFIPKIKSSDPVITGLFQYDAAQQTSFEKRMS
                     KENNGREAALANVIREYMSDLKLSSEQELNIQHLANGSKVVIGGQQAGLFGGPLYTFH
                     KIFSIITLSKELTDTHKQQVVPVFWIAGEDHDFDEVNHTFVYNENHGSLHKVKYHTME
                     MPETTVSRYYPDKAELKQTLKTMFILMKETVHTQGLLEICDRIIDQYDSWTDMFKAIL
                     HETFKAYGVLFIDAQFEPLRKMEAPMFKKILKKHQLLDDAFRATQQRTQNQGLNAMIQ
                     TDTNVHLFLHDENMRQLVSYDGKHFKLNKTDKTYIKEEIINIAENQPELFSNNVVTRP
                     LMEEWLFNTVAFVGGPSEIKYWAELKDVFELFDVEMPIVMPRLRITYLNDRIEKLLSK
                     YNIPLEKVLVDGVEGERSKFIREQASHQFIEKVEGMIEQQRRLNQDLLDEVAGNQNNI
                     NLVNKNNEIHIQQYDYLLKRYLLNIERENEISMKQFREIQETLHPMGGLQERIWNPLQ
                     ILNDFGTDVFKPSTYPPLSYTFDHIIIKP"
     gene            10510..10941
                     /gene="mraZ"
                     /locus_tag="RPH49_000718"
     CDS             10510..10941
                     /gene="mraZ"
                     /locus_tag="RPH49_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDY5123906.1"
                     /translation="MFMGEYDHQLDTKGRMIIPSKFRYDLNERFIITRGLDKCLFGYT
                     LDEWQQIEEKMKTLPMTKKDARKFMRMFFSGAVEVELDKQGRINIPQNLRKYANLTKE
                     CTVIGVSNRIEIWDRETWNDFYEESEESFEDIAEDLIDFDF"
     gene            10957..11892
                     /gene="rsmH"
                     /locus_tag="RPH49_000719"
     CDS             10957..11892
                     /gene="rsmH"
                     /locus_tag="RPH49_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017724209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDY5123907.1"
                     /translation="MFHHISVMLNETIDYLNVKENGVYIDCTLGGAGHALYLLNQLND
                     DGRLIAIDQDQTAIDNAKEVLKDHLHKVTFVHSNFRELTQILKDLNIEKVDGIYYDLG
                     VSSPQLDIPERGFSYHHDATLDMRMDQTQELTAYEIVNNWSYEALVKIFYRYGEEKFS
                     KQIARRIEAHREQQPITTTLELVDIIKEGIPAKARRKGGHPAKRVFQALRIAVNDELS
                     AFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVFQEYEKGPEVPRGLPVIPEAYTP
                     KLKRVNRKPITATEEDLDDNNRARSAKLRVAEILK"
     gene            11906..12307
                     /gene="ftsL"
                     /locus_tag="RPH49_000720"
     CDS             11906..12307
                     /gene="ftsL"
                     /locus_tag="RPH49_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDY5123908.1"
                     /translation="MAVEKVYQPYDEQVYNSIPKQQPQTKPEKKTVSRKVVVQLTKFE
                     KVLYITLITVIAMLSIYMLSLKMDAYDTRGKIADLDYKIDKQSSENSALQSEIKKNSS
                     YERIYEKAKKQGMSLENDNVKVVRSNGEAKN"
     gene            12288..14522
                     /locus_tag="RPH49_000721"
     CDS             12288..14522
                     /locus_tag="RPH49_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDY5123909.1"
                     /translation="MAKQKIKIKKNKIGAVLLVGLFGLLFFILVLRISYIMITGHSNG
                     QDLVMKANEKYLVKNAQQPERGKIYDRNGKVLAEDVERYKLVAVIDKKASANSKKPRH
                     VVDKKETAKKLSTVIDMKPEEIEKRLSQKKAFQIEFGRKGTNLTYQDKLKIEKMNLPG
                     ISLLPETERFYPNGNFASHLIGRAQKNPDTGELKGALGVEKIFDSYLSGSKGSLRYIH
                     DIWGYIAPNTKKEKQPKRGDDVHLTIDSNIQVFVEEALDGMVERYQPKDLFAVVMDAK
                     TGEILAYSQRPTFNPETGKDFGKKWANDLYQNTYEPGSTFKSYGLAAAIQEGAFDPDK
                     KYKSGHRDIMGSRISDWNRVGWGEIPMSLGFTYSSNTLMMHLQDLVGADKMKSWYERF
                     GFGKSTKGMFDGEAPGQIGWSNELQQKTSSFGQSTTVTPVQMLQAQSAFFNDGNMLKP
                     WFVNSVENPVSKRQFYKGQKQIAGKPITKDTAEKVEKQLDLVVNSKKSHAANYRIDGY
                     EVEGKTGTAQVAAPNGGGYVKGPNPYFVSFMGDAPKKNPKVIVYAGMSLAQKNDQEAY
                     ELGVSKAFKPIMENTLKYLNVGKSKDDTSNAEYSKVPDVEGQDKQKAIDNVSAKSLEP
                     VTIGTGTQIKAQSIKAGNKVLPHSKVLLLTDGDLTMPDMTGWTKEDVIAFENLTNIKV
                     NLKGSGFVSHQSISKGQKLTEKDKIDVEFSSENVDSNSTNNSDSNSDDKKKSDSKTDK
                     DKSD"
     gene            14814..15779
                     /locus_tag="RPH49_000722"
     CDS             14814..15779
                     /locus_tag="RPH49_000722"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDY5123910.1"
                     /translation="MIFVYALLALVITFVLVPVLIPTLKRMKFGQSIREEGPQSHMKK
                     TGTPTMGGLTFLLSIVITSLVAIIFVDQANPIILLLFVTIGFGLIGFIDDYIIVVKKN
                     NQGLTSKQKFLAQIGIAIIFFVLSNVFHLVNFSTSIHIPFTNVAIPLSFAYVIFIVFW
                     QVGFSNAVNLTDGLDGLATGLSIIGFTMYAIMSFVLGETAIGIFCIIMLFALLGFLPY
                     NINPAKVFMGDTGSLALGGIFATISIMLNQELSLIFIGLVFVIETLSVMLQVASFKLT
                     GKRIFKMSPIHHHFELIGWSEWKVVTVFWAVGLISGLIGLWIGVH"
     gene            15781..17130
                     /locus_tag="RPH49_000723"
     CDS             15781..17130
                     /locus_tag="RPH49_000723"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDY5123911.1"
                     /translation="MLNYTGLENKNVLVVGLAKSGYEAAKLLSKLGANVTVNDGKDLS
                     QDAHAKDLESMGISVVSGSHPLTLLDNNPIIVKNPGIPYTVSIIDEAVKRGLKILTEV
                     ELSYLISEAPIIAVTGTNGKTTVTSLIGDMFKKSRLTGRLSGNIGYVASKVAQEVKPT
                     DYLVTELSSFQLLGIEKYKPHIAIITNIYSAHLDYHENLENYQNAKKQIYKNQTEEDY
                     LICNYHQRQVIESEELKAKTLYFSTQQEVDGIYIKDGFIVYKGVRIINTEDLVLPGEH
                     NLENILAAVLACILAGVPIKAIIDSLTTFSGIEHRLQYVGTNRTNKYYNDSKATNTLA
                     TQFALNSFNQPIIWLCGGLDRGNEFDELIPYMENVRAMVVFGQTKAKFAKLGNSQGKS
                     VIEANNVEDAVDKVQDIIEPNDVVLLSPACASWDQYSTFEERGEKFIERFRAHLPSY"
     gene            17146..18465
                     /locus_tag="RPH49_000724"
     CDS             17146..18465
                     /locus_tag="RPH49_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDY5123912.1"
                     /translation="MDDKTKNDQQESNEDKDELELFTRNTSKKRRQRKRSKATHFSNQ
                     NKDDTSQQTDFDEEIYLINKDFKKEESNDENNDSASSHANNNNIDDSTDSNIENEDYR
                     YNQEIDDQNESNGIAVDNEQPQSAPKEQNSDSNDEETVTKKERKSKVTQLKPLTLEEK
                     RKLRRKRQKRIQYSVITILVLLIAVILIYMFSPLSKIAHVNINGNNHVSTSKINKVLG
                     VKNDSRMYTFSKKNAINDLEEDPLIKSVEIHKQLPNTLNVDITENEIIALVKYKGKYL
                     PLLENGKLLKGSNDVKINDAPVMDGFKGTKEDDMIKALSEMTPEVRRYIAEVTYAPSK
                     NKQSRIELFTTDGLQVIGDISTISKKMKYYPQMSQSLSRDSSGKLKTRGYIDLSVGAS
                     FIPYRGNTSSQSESDKNVTKSSQEENQAKEELQSVLNKINKQSSKNN"
     gene            18571..19977
                     /gene="ftsA"
                     /locus_tag="RPH49_000725"
     CDS             18571..19977
                     /gene="ftsA"
                     /locus_tag="RPH49_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDY5123913.1"
                     /translation="MEEHYYVSIDIGSSSVKTIVGEKFHNGINVIGTGQTYTSGIKNG
                     LIDDFDIARQAIKDTIKKASIASGVDIKEVFLKLPIIGTEVYDESNEIDFYEDTEING
                     SHIEKVLEGIREKNDVQETEVINVFPIRFIVDKENEVSDPKELIARHSLKVEAGVIAI
                     QKSILINMIKCVEACGVDVLDVYSDAYNYGSILTATEKELGACVIDIGEDVTQVAFYE
                     RGELVDADSIEMAGRDITDDIAQGLNTSYETAEKVKHQYGHAFYDSASDQDIFTVEQV
                     DSDETVQYTQKDLSDFIEARVEEIFFEVFDVLQDLGLTKVNGGFIVTGGSANLLGVKE
                     LLSDMVSEKVRIHTPSQMGIRKPEFSSAISTISSSIAFDELLDYVTINYHDNEETEED
                     VIDVKDKDNESKLGGFDWFKRKTNKKDTHENEVESTDEEIYQSEDNHQEHKQNHEHVQ
                     DKDKEESKFKKLMKSLFE"
     gene            20010..21182
                     /gene="ftsZ"
                     /locus_tag="RPH49_000726"
     CDS             20010..21182
                     /gene="ftsZ"
                     /locus_tag="RPH49_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDY5123914.1"
                     /translation="MLEFEQGFNHLATLKVIGVGGGGNNAVNRMIDHGMNNVEFIAIN
                     TDGQALNLSKAESKIQIGEKLTRGLGAGANPEIGKKAAEESREQIEDAIQGADMVFVT
                     SGMGGGTGTGAAPVVAKIAKEMGALTVGVVTRPFSFEGRKRQTQAAAGVEAMKAAVDT
                     LIVIPNDRLLDIVDKSTPMMEAFKEADNVLRQGVQGISDLIAVSGEVNLDFADVKTIM
                     SNQGSALMGIGVSSGENRAVEAAKKAISSPLLETSIVGAQGVLMNITGGESLSLFEAQ
                     EAADIVQDAADEDVNMIFGTVINPELQDEIVVTVIATGFDDKPTSHGRKSGSTGFGTS
                     VNTSSNATSKDESFTSNSSNAQATDSVSERTHTTKEDDIPSFIRNREERRSRRTRR"
     gene            21442..22233
                     /gene="pgeF"
                     /locus_tag="RPH49_000727"
     CDS             21442..22233
                     /gene="pgeF"
                     /locus_tag="RPH49_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan editing factor PgeF"
                     /protein_id="HDY5123915.1"
                     /translation="MNDNFKKQPHHLIYEELLQQGITLGITTRGDGLSDYPKNAFNMA
                     RYIDDRPYNITQHQLQLAEEIAFDRKNWVFPIQTHENKVACITKDDIGTNIDTLTDAL
                     HGIDAMYTYDSNVLLTMCYADCVPVYFYSTKHHFIALAHAGWRGTYTEIVKEVLKHVN
                     FDLKDLHVVIGPSTSSSYEINDDIKNKFETLPIDSANYIETRGRDRHGIDLKKANAEL
                     LNYYGVPKENIYTTAYATSEHLELFFSYRLEKGQTGRMLAFIGQQ"
     gene            22257..22925
                     /locus_tag="RPH49_000728"
     CDS             22257..22925
                     /locus_tag="RPH49_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDY5123916.1"
                     /translation="MKDNLQQISTQINDKSEKNNFSTKPNVIAVTKYVTIERAKEAYE
                     AGIRHFGENRLEGFFQKKEALPSDAVIHFIGSLQSRKVKDVINDVDYFHALDRLSLAK
                     EINKRAEHKIKCFLQVNVSGEASKHGIALEDVDQFIDDLKKYDKIEIVGLMTMAPLTD
                     DEAYIRSLFKQLRLKKEEIQRLNLEYAPCDELSMGMSNDYLIAVEEGATFVRIGTKLV
                     GEEE"
     gene            22922..23485
                     /locus_tag="RPH49_000729"
     CDS             22922..23485
                     /locus_tag="RPH49_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDY5123917.1"
                     /translation="MSHLALKDLFSGFFVIDDEEEVEVPDKQQQVNEAPAKEQSQQTT
                     KQNAIKSVPQKSASRYTTTSEERNNRMSNYSKNNSRNVVTMNNATPNNASQESSKMCL
                     FEPRVFSDTQDIADELKNRRATLVNLQRIDKVSAKRIIDFLSGTVYAIGGDIQRVGTD
                     IFLCTPDNVEVAGSITDHIENMEHSFD"
     gene            23497..23787
                     /locus_tag="RPH49_000730"
     CDS             23497..23787
                     /locus_tag="RPH49_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDY5123918.1"
                     /translation="MDINVLATIFKFILFVVEIYYFGMIIYFFTSWVPSIRETKVGYL
                     LAKIYEPFLQPFRKVIPPIGIIDISSIAAIIVLVLFQKGLLQIFNWILIQLQ"
     gene            23897..24676
                     /locus_tag="RPH49_000731"
     CDS             23897..24676
                     /locus_tag="RPH49_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDY5123919.1"
                     /translation="MINIDIYQHFRQEEYELIDQLTDKCDQAEHHYAPVLTHFLDPRG
                     QYILEVICGSYEDLNVSFYGGPNAERKRAIISPNYYEPKESDFELTLMEIEYPEKFVT
                     LKHQHILGTLMSLGIEREQVGDIIVNQRIQFVLTSRLESFIMLELQRIKGASVKLYTI
                     PVTDMIQSNENWKNESATVSSLRLDVVIKEMIRKSRTIAKQLIEKKRVKVNHTIVDSA
                     DFQLQANDLISIQGFGRAHITDLGGKTKKDKTHITYRTLFK"
     gene            24700..25317
                     /locus_tag="RPH49_000732"
     CDS             24700..25317
                     /locus_tag="RPH49_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDY5123920.1"
                     /translation="MPFTPNEIKNKEFSRVKNGLEPTEVANFLEQLSTEIERLKEDKK
                     QLEKVIEERDTNIKSYQDVHQSVSDALIQAQKAGEETKQAAEKQAEAIIAKAEAQANQ
                     MVGDAVEKARRLAFQTEDMKRQSKVFRSRFRMLVEAQLDLLKNEDWDYLLNYDLDAEQ
                     VTLENIHHLHENDLKPDEVAANAQNNASNTPDNNQQSNDSETTKK"
     gene            25538..28291
                     /gene="ileS"
                     /locus_tag="RPH49_000733"
     CDS             25538..28291
                     /gene="ileS"
                     /locus_tag="RPH49_000733"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDY5123921.1"
                     /translation="MDYKETLLMPKTDFPMRGGLPNKEPQIQEKWDAEDQYHKALEKN
                     KGNETFILHDGPPYANGNLHMGHALNKILKDFIVRYKTMQGFYAPYVPGWDTHGLPIE
                     QALTKKGVDRKKMSTAEFREKCKEFALEQIELQKKDFRRLGVRGNFNNPYITLKPEYE
                     AAQIRIFGEMADKGLIYKGKKPVYWSPSSESSLAEAEIEYHDKRSASIYVAFDVKDDK
                     GVVDADAKFIIWTTTPWTIPSNVAITVHPELKYGQYNVNGEKYIIAEALSDAVAEALD
                     WDKASIKLEKEYTGKELEYVVAQHPFLDRESLVINGDHVTTDAGTGCVHTAPGHGEDD
                     YIVGQKYELPVISPIDDKGVFTEEGGQFEGMFYDKANKAVTDLLTEKGALLKLDFITH
                     SYPHDWRTKKPVIFRATPQWFASISKVRQDILDAIENTNFKVNWGKTRIYNMVRDRGE
                     WVISRQRVWGVPLPVFYAENGEIIMTKETVNHVADLFAEHGSNIWFEREAKDLLPEGF
                     THPGSPNGTFTKETDIMDVWFDSGSSHRGVLETRPELSFPADMYLEGSDQYRGWFNSS
                     ITTSVATRGVSPYKFLLSHGFVMDGEGKKMSKSLGNVIVPDQVVKQKGADIARLWVSS
                     TDYLADVRISDEILKQTSDVYRKIRNTLRFMLGNINDFNPDTDSIPESELLEVDRYLL
                     NRLREFTASTINNYENFDYLNIYQEVQNFINVELSNFYLDYGKDILYIEQRDSHIRRS
                     MQTVLYQILVDMTKLLAPILVHTAEEVWSHTPHVKEESVHLADMPKVVEVDQALLDKW
                     RTFMNLRDDVNRALETARNEKVIGKSLEAKVTIASNDKFNASEFLTSFDALHQLFIVS
                     QVKVVDKLDDQATAYEHGDIVIEHADGEKCERCWNYSEDLGAVDELTHLCPRCQQVVK
                     SLV"
     gene            28582..29379
                     /locus_tag="RPH49_000734"
     CDS             28582..29379
                     /locus_tag="RPH49_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5123922.1"
                     /translation="MYHNSNANFVNGITLNVRDKNELKPFYEDVLGLNIINETLTSIQ
                     YEVGQNNHVITLVELQNGREPLMSEAGLFHIAIKLPQISDLANLLIHLSEYDIPVNGG
                     IQPASLSLFFEDPEGNGFKFYVDKDEAQWTRQNDLVKIDIRPLNVPRLVSHATKLLWL
                     GIPDDAIIGALHIKTIHLSEVKEYYLDYFGLEQSAYMDDYSIFLASNGYYQHLAMNDW
                     VSATKRVENFDTYGLAIVDFHYLETTHLNLQGPDGIYYRFNHIEVEG"
     gene            29766..30050
                     /locus_tag="RPH49_000735"
                     /pseudo
     CDS             29766..30050
                     /locus_tag="RPH49_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            30274..30765
                     /gene="lspA"
                     /locus_tag="RPH49_000736"
     CDS             30274..30765
                     /gene="lspA"
                     /locus_tag="RPH49_000736"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDY5123923.1"
                     /translation="MHKKYFIGTSILIAVFVVIFDQVTKYIIATTMKIGDSFEVIPHF
                     LNITSHRNNGAAWGILSGKMTFFFIITIIILIALVYFFIKDAQYNLFMQVAISLLFAG
                     ALGNFIDRILTGEVVDFIDTNIFGYDFPIFNIADSSLTIGVILIIIALLKDTSNKKEK
                     EVK"
     gene            30765..31682
                     /locus_tag="RPH49_000737"
     CDS             30765..31682
                     /locus_tag="RPH49_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDY5123924.1"
                     /translation="METYEFNITDKEQTGMRVDKLLPELNSDWSRNQIQDWIKAGLVV
                     ANDKVVKSNYKVKLNDHIVVTEKEVVEADILPENLNLDIYYEDDDVAVVYKPKGMVVH
                     PSPGHYTNTLVNGLMYQIKNLSGINGEIRPGIVHRIDMDTSGLLMVAKNDIAHRGLVE
                     QLMDKSVKRKYIALVHGNIPHDYGTIDAPIGRNKNDRQSMAVVDDGKEAVTHFNVLEH
                     FKDYTLVECQLETGRTHQIRVHMKYIGFPLVGDPKYGPKKTLDIGGQALHAGLIGFEH
                     PVTGEYIERHAELPQDFEDLLDTIRKRDA"
     gene            32082..32609
                     /gene="pyrR"
                     /locus_tag="RPH49_000738"
     CDS             32082..32609
                     /gene="pyrR"
                     /locus_tag="RPH49_000738"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDY5123925.1"
                     /translation="MSERIIMDDAAIQRTVTRIAHEILEYNKGTDNLILLGIKTRGEY
                     LANRIQDKIHQIEQQRIPTGTIDITYFRDDIEHMSSLTTKDAIDIDTDITDKVVIIID
                     DVLYTGRTVRASLDAILLNARPIKIGLAALVDRGHRELPIRADFVGKNIPTSKEETVS
                     VYLEEMDQRNAVIIK"
     gene            32827..34134
                     /locus_tag="RPH49_000739"
     CDS             32827..34134
                     /locus_tag="RPH49_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDY5123926.1"
                     /translation="MQNDEMFERTVKPVLDVNEKPQPAQWAFLSLQHLFAMFGATVLV
                     PFLTGLPISAALLASGIGTLLYILITKAQIPAYLGSSFAFITPIITGLSTHSLGDMLV
                     ALFMSGVMYVIIGILIKLSGTAWLMKLLPPVVVGPVIMVIGLSLAPTAVNMAMYENPG
                     DMKGYNISFLIVAMITLLVTIVVQGFFKGFLSLIPVLVGIIVGYVVAIFMGIVKFDAI
                     MSAKWIDFPHIYLPFKDYVPSFHLGLVLVMIPIVFVTVSEHIGHQMVLNKIVGRNFFE
                     KPGLDKSIIGDGVSTMFASIIGGPPSTTYGENIGVLAITRIYSIYVIGGAAVIAIVLA
                     FIGKFTALISSIPTPVMGGVSILLFGIIAASGLRMLVESKVDFANNRNLVIASVILVV
                     GIGNLVFNLKEIGINFQIEGMALAALSGIILNLILPKEKKQNN"
     gene            34162..35043
                     /locus_tag="RPH49_000740"
     CDS             34162..35043
                     /locus_tag="RPH49_000740"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDY5123927.1"
                     /translation="MNHLLSMEHLSTDQIYKLIQKASQFKSGERQLPNFEGKYVANLF
                     FENSTRTKCSFEMAELKLGLKTISFETSTSSVSKGESLYDTCKTLESIGCDLLVIRHP
                     FNNYYEKLANINIPIANAGDGSGQHPTQSLLDLMTIYEEYGYFEGLNVLICGDIKNSR
                     VARSNYHSLKALGANVMFNSPNAWIDDSLEAPYVNIDDVIETVDIVMLLRIQHERHGL
                     AEETRFAADDYHQKHGLNEVRYNKLQEHAIVMHPAPVNRGVEIQSDLVEASKSRIFKQ
                     MENGVYLRMAVIDELLK"
     gene            35061..36335
                     /locus_tag="RPH49_000741"
     CDS             35061..36335
                     /locus_tag="RPH49_000741"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDY5123928.1"
                     /translation="MKLIKNGKVLQNGELQQADILIDGKVIKQIAPAIEPSNGVDIID
                     AKGHFVSPGFVDVHVHLREPGGEYKETIETGTKAAARGGFTTVCPMPNTRPVPDSVEH
                     FEALQKLIDDNAQVRVLPYASITTRQLGKELVDFPALVKEGAFAFTDDGVGVQTASMM
                     YEGMIEAAKVNKAIVAHCEDNSLIYGGAMHEGKRSKELGIPGIPNICESVQIARDVLL
                     AEAAGCHYHVCHVSTKESVRVIRDAKRAGIHVTAEVTPHHLLLTEDDIPGNNAIYKMN
                     PPLRSTEDREALLEGLLDGTIDCIATDHAPHARDEKAQPMEKAPFGIVGSETAFPLLY
                     THFVKNGDWTLQQLVDYLTIKPCETFNLEYGTLKENGYADLTIIDLDSEQEIKGEDFL
                     SKADNTPFIGYKVYGNPILTMVEGEVKFEGDK"
     gene            36337..37437
                     /gene="carA"
                     /locus_tag="RPH49_000742"
     CDS             36337..37437
                     /gene="carA"
                     /locus_tag="RPH49_000742"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDY5123929.1"
                     /translation="MQSKRYLVLEDGSFYEGYRLGSDNLTVGEIVFNTAMTGYQETIS
                     DPSYTGQIITFTYPLIGNYGINRDDFESLVPTLNGIVVKEASAHPSNFRQQKTLHDVL
                     ELHQIPGIAGVDTRSITRKIRQHGVLKAGFTDRKEDIDQLVKHLQQVELPKNEVEIVS
                     TKTPYVSTGKDLSVVLVDFGKKQNIVRELNVRGCNVTVVPYTTTAEEILAMAPDGVML
                     SNGPGNPEVVECAIPMIQGILGKIPFFGICLGHQLFALSQGASSFKMKFGHRGANHPV
                     KNLETGKVDITSQNHGYAIDIDSLKSTDLEVTHLALNDGTVEGLKHKTLPAFSVQYHP
                     EANPGPSDSNYLFDDFVAMMTNFKEKERHINA"
     gene            37430..40603
                     /gene="carB"
                     /locus_tag="RPH49_000743"
     CDS             37430..40603
                     /gene="carB"
                     /locus_tag="RPH49_000743"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDY5123930.1"
                     /translation="MPKRNDIKTILVIGSGPIIIGQAAEFDYAGTQACLALKEEGYRV
                     ILVNSNPATIMTDKEIADKVYIEPLTHDFIARIIRKEQPDALLPTLGGQTGLNMAIQL
                     HESGVLQDNNVQLLGTELTSIQQAEDREMFRTLMNDLNVPVPESDIVNTVEQAFKFKE
                     QVGYPLIVRPAFTMGGTGGGICHNDEELHEIVSNGLHYSPATQCLLEKSIAGFKEIEY
                     EVMRDKNDNAIVVCNMENIDPVGIHTGDSIVVAPSQTLSDVEYQMLRDVSLKVIRALG
                     IEGGCNVQLALDPHSFDYYIIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEM
                     LNPITGTSYAAFEPTLDYVISKIPRFPFDKFEKGERELGTQMKATGEVMAIGRTYEES
                     LLKAIRSLEYGVHHLGLPNGESFDLDYIKERISHQDDERLFFIGEAIRRGTTLEEIHN
                     MTQIDYFFLHKFQNIIDIEHQLKEHQGDLEYLKYAKDYGFSDKTIAHRFNMTEEEVYQ
                     LRMENDIKPVYKMVDTCAAEFESSTPYYYGTYETENESIVTDKEKILVLGSGPIRIGQ
                     GVEFDYATVHAVWAIQKAGYEAIIVNNNPETVSTDFSISDKLYFEPLTEEDVMNIINL
                     EKPKGVVVQFGGQTAINLADKLAKHGVKILGTSLENLNRAEDRKEFEALLRKINVPQP
                     QGKTATSPEEALANAAEIGYPVVVRPSYVLGGRAMEIVDNDKELENYMTQAVKASPEH
                     PVLVDRYLTGKEIEVDAICDGETVIIPGIMEHIERAGVHSGDSIAVYPPQTLTEDELA
                     TLEDYTIKLAKGLNIIGLINIQFVIAHDGVYVLEVNPRSSRTVPFLSKITDIPMAQLA
                     MRAIIGEKLTDMGYQEGVQPYAEGVFVKAPVFSFNKLKNVDITLGPEMKSTGEVMGKD
                     TTLEKALFKGLTGSGVEVKDHGTVLMTVSDKDKEEVVKLAQRLNEVGYKILATSGTAN
                     KLAEYDIPAEVVGKIGGENDLLTRIQNGDVQIVINTMTKGKEVERDGFQIRRTTVENG
                     IPCLTSLDTANALTNVIESMTFTMRQM"
     gene            40713..41405
                     /gene="pyrF"
                     /locus_tag="RPH49_000744"
     CDS             40713..41405
                     /gene="pyrF"
                     /locus_tag="RPH49_000744"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDY5123931.1"
                     /translation="MKDLPIIALDFESKEKVNQFLDLFDESLFVKVGMELFYQEGPQL
                     INEIKERGHDVFLDLKLHDIPNTVGKAMERLAKLNVDLVNVHAAGGVKMMSEAIKGLR
                     KHNQHTKIIAVTQLTSTTEDMLRHEQNIQTSIEEAVLNYAKLANAAGLDGVVCSPLES
                     RMLTEKLGTSFLKVTPGIRPKGASQDDQHRITTPEEARQLGSTHIVVGRPITQSDNPV
                     ESYHKIKESWLV"
     gene            41405..42016
                     /locus_tag="RPH49_000745"
     CDS             41405..42016
                     /locus_tag="RPH49_000745"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDY5123932.1"
                     /translation="MAKEIAKSLLDIEAVTLSPNDLYTWSSGIKSPIYCDNRVTLGYP
                     LVRGAIRDGLINLIKEHFPEVEVISGTATAGIPHAAFIAEKLKLPMNYVRSSNKSHGK
                     QNQIEGAKSEGKKVVVIEDLISTGGSSVTAVEALKQAGAEVLGVVAIFTYGLKKADDT
                     FSNIQLPFYTLSDYNELIEVAENEGKISSEDIQTLVEWRDNLA"
     gene            42046..42258
                     /locus_tag="RPH49_000746"
     CDS             42046..42258
                     /locus_tag="RPH49_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123933.1"
                     /translation="MNDKTSNDLYGKIKHCNEFINHSNDSNLSSSHDVDESSTKQKHI
                     KNKTTIDHNDDLFKHVKDILRKQGQI"
     gene            42695..43096
                     /locus_tag="RPH49_000747"
     CDS             42695..43096
                     /locus_tag="RPH49_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5123934.1"
                     /translation="MDIPKITTFLMFNNQAEEAVKLYTSLFEDSEIITMAKYGENGPG
                     DPGTVQHSIFTLNGQVFMAIDANSGTELPMNPAISLFVTVKDTIEMERLFNGLKDEGA
                     ILMPKTNMPPYREFAWVQDKFGVSFQLALPE"
     gene            complement(43359..45056)
                     /locus_tag="RPH49_000748"
     CDS             complement(43359..45056)
                     /locus_tag="RPH49_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NFACT family protein"
                     /protein_id="HDY5123935.1"
                     /translation="MAYDGLFTKKMVESLQFLTTGRVHKINQPDNDTILMVVRQNRQN
                     HQLLLSIHPNFSRLQLTTKKYDNPFNPPMFARVFRKHLEGGIIESIKQIGNDRRIEID
                     IKSKDEIGDTIYRTVILEIMGKHSNLILVDENRKIIEGFKHLTPNTNHYRTVMPGFNY
                     EAPPTQHKMNPYDITGAEVLKYIDFNAGNIAKQLLNQFEGFSPLITNEIVNRRQFMTS
                     STLPEAFDEVMAETKLPPTPIFHKNHETGKEDFYFIKLNQFNDDTVTYDSLNDLLDRF
                     YDARGERERVKQRANDLVRFVQQQLHKYQNKLAKLIEEYEQSKNKDTEQLYGELITAN
                     IYRIKQGDKEVTALNYYTNEEVVIPLNPTKSPSANAQYYYKQYNRMKTRERELQHQIQ
                     LTKDNIDYFSTIEQQLHHISVHDIDEIRDELAEQGFMKQRKNQTKKKKAQIQLQHYVS
                     TDGDDIYVGKNNKQNDYLTNKKAKKTHTWLHTKDIPGSHVVIFNDAPSDTTIKEAAML
                     AGYFSKAGNSGQIPVDYTLIKNVHKPSGAKPGFVTYDNQKTLYATPDYELIQKMKQS"
     gene            45331..45954
                     /gene="gmk"
                     /locus_tag="RPH49_000749"
     CDS             45331..45954
                     /gene="gmk"
                     /locus_tag="RPH49_000749"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDY5123936.1"
                     /translation="MDNEKGLLIVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQ
                     MREGEVDGVDYFFKTRDAFEALIKDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFL
                     EIEVEGAKQVRKKFPDALFIFLAPPSLDHLRERLVGRGTESDEKIQSRINEARKEVEM
                     MNLYDYVVVNDEVELAKNRIQCIVEAEHLKRERVEAKYRKMILEAKK"
     gene            45954..46172
                     /locus_tag="RPH49_000750"
     CDS             45954..46172
                     /locus_tag="RPH49_000750"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDY5123937.1"
                     /translation="MLNPPLNQLTSQIKSKYLIATTAAKRAREIDEQPETELLSEYHS
                     FKPVGRALEEIADGKIRPVISSDYYGKE"
     gene            46388..47587
                     /gene="coaBC"
                     /locus_tag="RPH49_000751"
     CDS             46388..47587
                     /gene="coaBC"
                     /locus_tag="RPH49_000751"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDY5123938.1"
                     /translation="MKKILLAVTGGIAAYKAIDLTSKLTQSGYEVRVMLTNHAQKFVT
                     PLAFQAISRNAVYTDTFIEENPSEIQHIALGDWADAIIVAPATANTIAKLSVGIADDL
                     VTSTLLATETPKFIAPAMNVHMYENKRTQQNINILKEDGYHFIEPGSGFLACGYVAKG
                     RMEEPLQIVSVIDAHFQNSNRLANSSFQDKRALVTAGPTIEVIDPVRFVSNRSSGKMG
                     YAIAEALRNRGAIVTLVAGPTTLEDPKDIEVIHVQSAEEMFEQVTSRFDEQDIVVKAA
                     AVSDYTPVDVLEHKMKKQDGDLSVSFKRTKDILKYLGEHKTSQYLIGFAAETEDIENY
                     AQQKLRKKNADVIISNNVGDMSIGFSSDDNELTMHFKNNEKVNIKKGKKVVLAAQILD
                     ELETRWQ"
     gene            47587..49995
                     /gene="priA"
                     /locus_tag="RPH49_000752"
     CDS             47587..49995
                     /gene="priA"
                     /locus_tag="RPH49_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDY5123939.1"
                     /translation="MIAKVIVDVASKSVDFKFDYIIPEQLESVIQPGVRVIVPFGPRT
                     IQGYVMEVTAEPDAQLDVSKLKKIIEVKDIQPELTSELIALSEWMGSTHVIKRISMLE
                     VMLPSAIKAKYKKAFKMKDDIELPSALLQKFDKHGYYYYKDAQKNNDIQLLMKLLKDD
                     IVEEKTILTQNITKKTKRAVRVIEGYHPDEVLAKLEKVIKQYDLYAYLSEEQHKTIFL
                     TDIEDMGFSKSSLDGLIKKGYVEKYDAVVDRDPFKDRVFEQESKQQLTEDQYKAYEAI
                     KAKIVSQEQETFLLHGVTGSGKTEVYLQTIEDVLSQGKQAMMLVPEIALTPQMVLRFK
                     RRFGDDVAVLHSGLSNGERYDEWQKIRDGRARVSVGARSSVFAPFKNLGLIIIDEEHE
                     STYKQEDYPRYHAREIAQWRSEYHHCPVILGSATPCLESYARAEKGVYHLLSLPNRVN
                     QQALPEIDIVDMREELSEGNRSMFSKDLREAIQLRLDRQEQVVLFLNRRGYASFMLCR
                     DCGYVPQCPNCDISLTYHKTTDLLKCHYCGYQETPPNQCPNCESEHIRQVGTGTQKVE
                     ELLQQEFEDARIIRMDVDTTSKKGAHEKLLTEFEKGNGDILLGTQMIAKGLDYPNITL
                     VGVLNADTMLNLPDFRASERTYQLLTQVAGRAGRHEKAGQVIIQTYNPDHYSILDVQK
                     NDYLTFYRQEMEYRKLGKYPPYYYLINFTISHKEMKKVMEASQHVHKILLQHLTEKAL
                     VLGPSPAALVRINNEFRFQILVKYKSEPGLLQAIQFLDDYYHEKFIKEKLALKIDIDP
                     QMMM"
BASE COUNT        18109 a         7089 c         9506 g        15564 t
ORIGIN      
        1 attttgtatg cgcttacaat ttaggtgtaa ctaatataaa aggagttgtt attaatgaaa
       61 aatttacgaa acagaagttt tttaacttta ttagactttt cacgacaaga ggtagaattc
      121 ttattaacac tctccgagga tttaaaacgt gctaaatata ttggcactga aaagcctatg
      181 ttaaaaaata aaaatattgc actgttattt gaaaaagatt ctacaagaac acgatgtgca
      241 tttgaagttg cagcacatga tcaaggtgca aatgtaactt atttaggccc aactggatca
      301 caaatgggta aaaaagaaac aactaaagat actgcacgtg tgcttggtgg aatgtatgat
      361 ggcattgaat accgtggttt ttcacaaaga acagtagaaa ctttagctga atattcaggc
      421 gtaccagtgt ggaatggttt aactgatgaa gatcatccta ctcaagttct tgctgatttc
      481 ttaacagcaa aagaagtctt aaaaaaagat tatgcagata ttaactttac atatgttgga
      541 gatggtcgta ataacgttgc aaatgcatta atgcaaggtg ctgccattat gggtatgaac
      601 ttccatttag tttgtccaaa agaattaaat ccaacagatg aattattaaa tcgctgtaaa
      661 aatattgccg ctgaaaatgg tggcaacata ttaatcacag atgatattga ccaaggtgta
      721 aaaggttcgg atgtaattta cactgatgtt tgggtatcaa tgggtgaacc tgatgaagta
      781 tggaaagaac gacttgaatt attgaaacca tatcaagtaa ataaagaaat gatggataaa
      841 actggtaatc caaatgttat ttttgagcat tgcttaccat ctttccataa tgctgatacg
      901 aaaattggtc aacaaatttt tgaaaaatat ggaattcgag aaatggaagt tacagatgaa
      961 gtattcgaaa gtaaagcttc agttgtattc caagaagctg agaacagaat gcatacaatc
     1021 aaagcagtca tggttgctac attgggtgaa ttttaaatga tataaggaag tgaatatgat
     1081 ggcgaaaata gtagtagcat taggtggtaa tgctttagga aaatcacctc aagaacaact
     1141 cgagcttgtt aaaaatactg cgaaatcatt agtaggatta ataacaaaag gacatgagat
     1201 tgttattagt catggtaatg ggccacaggt tggaagcatt aatttgggac ttaactatgc
     1261 tgcagaacac aaccaaggtc cggcatttcc atttgctgaa tgtggcgcaa tgagtcaagc
     1321 ttacataggc tatcaattac aagaaagctt acaaaacgaa ttgcattcta ttggaatgga
     1381 taaacaagtg gtaacactag tgacacaagt tgaagttaat gaaaatgatc cggcatttaa
     1441 caatccttca aaaccaattg ggttatttta caacaaagaa gaagctgaac aaattcaaaa
     1501 agaaaaagga tttatatttg ttgaagatgc tggaagagga tatagacgtg ttgttccttc
     1561 accacaaccc atctctatta ttgaattaga gagtattaaa acacttatta aaaatgatac
     1621 actcgttatt gctgctggtg gtggagggat accagtaatt agagagcaac atgatggttt
     1681 taaaggtatt gatgcagtta tagacaaaga taaaacaagt gcgttgttgg gtgctaatat
     1741 tcaatgcgat caattgatta ttttaacagc aattgattat gtatatatta attttaacac
     1801 tgaaaaccaa cagcctttgg aaacaacaaa tgttgatgaa ttaaaacgat atatagacga
     1861 aaatcaattt gcaaaaggaa gtatgttacc aaaaattgaa gcagccatat catttattga
     1921 aaacaatcca aaaggaagtg tgcttataac atcattaaat gaattagatg ctgccttaga
     1981 gggtaaagta ggtactgtga ttaaaaagta attgaattga aacgcttttc aattactata
     2041 tgtcaaatgc atgattttta ttatttatgt gcacccctga aaataatgcc tctattttga
     2101 tgcggggtgc actttcttaa tttatattta taaaatcttt aaggtagaaa tgctaggtta
     2161 aatgtcgaag gagatgaaac cgtggaaaat acaattaatg aaagtgaaaa gaaaaaacga
     2221 tttaaattaa aaatgccagg tgcatttatg attttattca ttttaacggt tgttgcagtt
     2281 atagcaacat gggttattcc tgctggtgca tattctaaac tttcttacga accttcatcc
     2341 caagaactaa agatagttaa ccctcataac caagtgaaaa aggttccggg tacgcaacag
     2401 gaactagaca aaatgggggt taaaattaag attgaacaat ttaaatcagg tgcaattaat
     2461 aagccggtat caattccgaa tacttatgaa agattaaagc aacatccagc tggaccagaa
     2521 caaataacaa gtagcatggt tgaaggtacg atagaagcgg tcgatatcat ggtattcatt
     2581 cttgtactag ggggacttat tggcgtagtt caagccagtg gttcttttga atcgggattg
     2641 ttagctttaa cgaagaaaac aaaagggcat gaatttatgc taattgtgtt tgtatcaata
     2701 ctaatgatta tcggcgggac attatgtggt attgaagaag aagctgtagc attctatccg
     2761 attttagtcc ctatatttat agcgttagga tacgattcta tcgtttcagt tggtgccata
     2821 ttccttgcca gctctgtcgg tagtacattt tcaactatta acccgttctc ggttgtaatt
     2881 gcctctaatg ccgctggtac aacttttacg gatggcttgt attggagaat aggcgcttgt
     2941 attgtcggtg cgatttttgt tattagttat ttatattggt actgtaaaaa aattaaaaaa
     3001 gatcctaaag cgtcatattc ttatgaagac aaagatgctt ttgaacagca atggtctgta
     3061 ttaaaagatg acgatagtgc ccattttact ttgcgtaaga agataatcct tacattattt
     3121 gtactaccat ttccaattat ggtatgggga gttatgacgc aaggttggtg gttcccagtt
     3181 atggcttcag catttttaat atttgcaatt ataataatgt ttattgctgg gacaggtaaa
     3241 tctggattgg gagaaaaagg aactgtagat gcatttgtca atggcgcatc aagtttagta
     3301 ggtgtatctt taattattgg cttagctcga ggtattaatt tagtgttgaa tgaaggtatg
     3361 atttcagata caatcttaca cttttcatca tctttagttc aacatatgag tggaccatta
     3421 tttatcatcg tattactatt tattttcttc tgtttaggtt ttatcgtgcc atcatcttct
     3481 ggattagcgg tattatcaat gcctatcttt gcaccactag ctgatacagt aggtatacca
     3541 agattcgtca tcgttacgac atatcaattt ggtcaatatg cgatgttatt cttagcgccg
     3601 actggacttg ttatggccac actacaaatg ttaaacatgc gatattcaca ttggttccga
     3661 tttgtatggc cggtagttgc ttttgtattg attttcggtg gcggagtact aattacgcaa
     3721 gtactaattt attcataatt tgaaatgcta tattataaaa atactaattg ggttttatgc
     3781 atctcgtagg tttgtagaaa tactaaacta agcgaggtgc attattattt ttgattaaga
     3841 aaataatgac ggtaatcata acactagtaa gtaattgata caatgctcta tttaataatg
     3901 atatttttaa aatttgtttt taatgtaatg ttagatctat ggtatattat atttatcgtg
     3961 gtaaatatgt atttgctgta aacagttttt gtaacacatg acacatatgg ttgtgaaaat
     4021 agcatatata aaggatggct ataaatgaca catttgacaa aggttttaga tacactaact
     4081 ggaatatgcg tagtattatt atttagtaaa tattttgtgg cgtatgcaaa tatggtgttt
     4141 gattggaagt taagatggta tttgctagaa aacataccac atttgccaat tatattattt
     4201 attctgatgt ttattttcgg agtaccttct gaaatgataa aagataggca aaggaaaaat
     4261 aacggcgttt aatttatcga tatttagagg tgataaaatt tgtcaactat tacaaagact
     4321 aaaataaaaa tctttattaa ttattttatt ggtatattag ccttggcgtt tgctgcttat
     4381 atattattta aataaaggtt agagtgaaac gtgtttatga actagacgtt ctagtatagt
     4441 tactacagct ttagtcagaa ggtatcattg atatgatcat attaaatcaa agaggcattg
     4501 atatacacta aaaagaggca agattacctg cctctttttt agttattaaa tatgcgtgtt
     4561 aattcttggt aatagtgtta ctgagacgca ttacgaagaa atttatcttg attttccttt
     4621 tttaaaaaga agtgaagata tcctataaag actctaagta ctattacagt agctaataac
     4681 acttcgataa acaaaagacc tttccaaatg tctggaaaca taagtacagg caaactgttc
     4741 tttaaagcag ttgctgagat tactaaaggg aatgtgaaag ctgaaaatac gggcgaaaaa
     4801 ggttctttta gtaatttagg caattgtata atgatataaa aataaaatat ttgagctaat
     4861 attaaaaata taattacgat aaaagcattc gccttaggaa atgctataac atatgctgca
     4921 gcgactaaag aaaatggtgc acaaattgtc gatgtgttcg gtttgattga cgtctgcaat
     4981 ggaaatgctt ttaatcgctt gaaaacaata ggtaagacaa tacaagtagc tacaaagcca
     5041 tatattactg ttaattgacc tatgaaaaaa tatccgctaa cgggtgccgt caatcctgcg
     5101 atagcaatac caataaaaag tacagtccac gaaggataaa cattttcaag tgaaaaatct
     5161 tttaaatatt ttattgaaaa aataatcata tgcgtcataa ttcccacaag gcataaaatc
     5221 caaataggcg ttattaagct attgataaaa gttatgttac taaaaaatgt atttaaataa
     5281 gtagtaccta aaaagccaga catgaaaaat gttgtgaaca ctgatgaaac tagaggactg
     5341 tttaattgtt ctttcacatt attagaatat ttgagcatag tacataaaag gtgaatccaa
     5401 atcaagaaag caaagattcc gcaaacagcg tttaaagtaa gagataagtc ttttaataga
     5461 ttacccaggc ctaataatcc taagattagt cctgacgtta ctaaaggtgc tttttgaagt
     5521 ctcatgattt acaacctttc ttatgtgatt ttcttcacta attatatcat gatagctatg
     5581 gccaattaat aagaagagtg tgtactatta cgttattaga gtatgtatat tggattgata
     5641 gacacataat tgacatttaa atctcaaaat taatgatatt tgaggtatgc tttgcaacct
     5701 aaatattgga atatgtggaa aagtaattat ttaatttaaa tgatgattga agatttacaa
     5761 gggggtgtac aaaatgagaa atcaaattca aaaactatta gacagtgatt tgagcagttt
     5821 acatatatcg aaacaaacag gagttccaca aagcacaata cacagaatga gaaaaaaaga
     5881 aagatcatta gacaatatgt cattgaaaaa cgctgaacta ctttataaat ttgccaatag
     5941 tatatttagc aatgaaaatt aagaagaata attagtgaat taaataatta aaaaaccacg
     6001 tcttgatgga cgtggttatt tttttaagat gtatataatt ataggatttc gggtccctga
     6061 aaagtcccta aaattttgaa tagtatcaaa atctataaga ataatataat aataaaaatc
     6121 tctacgcatg caaatggtga gtgttaaaaa tcttggtgta gtgttggtgt agttcaggtg
     6181 cagtatagat gaaatttgag cacaaaatta cttaattaaa aatgtataaa caagtgtcag
     6241 acgcgtgtca attgtgtgtc aaaaaattct ataacgaata agcatgcttg ttttaattac
     6301 tgtattttcg gggcttatgc gggggacgtt ttggtgacgc atcatactat aatactgaaa
     6361 ttcaaaacaa aaagagcccc gtaatcacgg aactcttttg tttggtaatg cgtataaaaa
     6421 tacctataaa cgtcctggga gggattcgaa cccccgaccg atggcttaga aggccattgc
     6481 tctatccagc tgagctacca ggacacgttt aacaacacaa gaattattat atctaaatga
     6541 acttaaatta gcaatacctt gtaaataaaa aatgtttata tttttcacta ttatagagct
     6601 atttatctaa aaaggttcaa taagacttaa atacgaattc aggcaactta attgtgttaa
     6661 atacagtttt gaatgcctaa ctgtatttct tttctcttta aaatacagtt aagtacatta
     6721 taagatgttg tgcggataaa caaactaatt gcatcaaatt tattttaaaa taacaacaac
     6781 aaaacgttaa gcgaataaca tttcggtgat ttaaaagcta cgcacgtttt tgttatcttc
     6841 aaatttaaat tttaaggagt gttttcaatg gaaggtttat ttaacgcaat taaagatacc
     6901 gtaactgcag caattaataa tgacggcgca aaattaggca caagcattgt gagcatcgtt
     6961 gaaaatggcg taggtttatt aggtaaatta ttcggattct aatatcaata tgttatgtaa
     7021 gtaataagta ttatttcaaa ggtgagggag agatttaaat gactggacta gcagaagcaa
     7081 tcgcaaatac tgtgcaagct gcacaacaac atgatagtgt gaaattaggc acaagtatcg
     7141 tagacatcgt tgctaacggt gtgggtttac taggtaaatt atttggattc taatataata
     7201 actaatattc tttaaaataa actgggtgag catactttaa tgttatgcac tcagtttatt
     7261 ttatttgcag aaatttgagc ctctgttaag atttagatac atagacaata taggagatgg
     7321 ggaaattggg atataaaaat attttgatag actttgatga tacaattgtt gatttttatg
     7381 atgcagaaga atgggcgttt cactatatgg cgaatgtttt taatcataaa gcaacaaaag
     7441 atgatttttt aacatttaaa aaaatcaatc accaacattg ggaagctttt caacaaaata
     7501 aattaacgaa gtctgaagta ttatcagaac gatttgtgaa ttacttcaaa catcatcaaa
     7561 tggaagttga tgggcatcgt gcagatgtgt tatttagaaa tggattagca gaagctaaag
     7621 ttaaatactt tgatcaaaca ttagaaacaa ttgtcgaatt atcgaaaaga catgatttat
     7681 atattgttac taatggtgta accgaaacgc aaaagagaag gttaaatcag acgccgttgc
     7741 ataaatatat taaaaagata tttatatctg aggaaacagg atatcaaaaa cctaatccgg
     7801 aattttttaa ttatgttttt aatgatattg gtgaggatga aagacagcac tcgattatag
     7861 ttggagattc tttaacatct gacattctag gtggaatcaa tgcgggtata gctacttgct
     7921 ggtttaattt tagaggattt gatcataatc catgaattat acctgattat gaaattaatt
     7981 catggaaaca actaaatgat attgtacgtt aagacaaata atttgaaaat gatttactat
     8041 tagcttaaga aagtaattgt aaaaaagaca ctacgaaaag atgcattttc atgctggtag
     8101 tgtcgaatat tattgtctta tggtttccac aataagacat catgtccctc tatattttta
     8161 gcttccacat ctgtaaatcc atgatgtaaa aagaaatcct tagaatcatt tctgccaatg
     8221 gctttaattg gcatgttgaa actctttgca aaatcaatca attctgaagc gtaccctctg
     8281 ttttgatatt ttggtaatac ttctaacttc cataataata tataatcttc aaaatctggg
     8341 aagtagattt cttcgacatc accttttttt agtaatgcca ttctagctcc taattgatct
     8401 ccgacaaata tgccataaaa tggtgaatct gaacttgcat caatcatttg accgtttaac
     8461 tcattgacca tgtataagtc tttgttgcca aacgctctaa agttttcgaa taattcgtca
     8521 gttttgtaat taatttcaag acgtttgatt tcactcatat ttatctaccc cttatttgtt
     8581 tactactatt attatacatt aaaccacttg tgtttttcat tgatttgaaa atgtaaaaca
     8641 atgaatatta taaattttcc atgattaaat tgattttcaa gccgtaaaat tgtcaatcac
     8701 cggtatagac tttatactat agtttgtaat cgcgtactta aggagaaaaa acatggactg
     8761 taaagtagtt agtttaaatg aaaaagatca gtttatacca aaaataaaga gcagtgaccc
     8821 tgtaataaca ggattatttc aatatgacgc agctcaacaa actagttttg aaaaaaggat
     8881 gtctaaagaa aataatggaa gagaagcggc attagcgaat gttattcgtg aatatatgag
     8941 tgatttaaag ctttctagtg aacaagaatt aaacatacaa catttagcta atggttcaaa
     9001 agttgtgatt ggtggacaac aagcagggct tttcggggga ccattgtata cattccataa
     9061 aatattttca atcattactt tatctaagga attaacggat acacataagc aacaagtagt
     9121 accagttttt tggattgcag gagaagatca tgatttcgat gaagtgaatc atacatttgt
     9181 ttataacgaa aatcatgggt cgctgcataa ggttaaatat catacaatgg agatgccaga
     9241 gacgactgtc tctagatatt atcctgataa ggctgagttg aaacaaactt taaaaacgat
     9301 gttcattctt atgaaagaaa ctgttcatac acaaggtcta ctggagattt gtgacagaat
     9361 tattgaccaa tatgactcgt ggactgatat gtttaaagca atactgcatg aaacatttaa
     9421 agcatatggc gttctattta tagatgcgca gtttgagccg ttaagaaaaa tggaagcgcc
     9481 tatgtttaaa aagattttga aaaaacatca gttgcttgat gatgctttta gagcaacaca
     9541 acaacgtact caaaatcaag gcttgaatgc gatgatacaa acagatacaa atgttcattt
     9601 attcttacat gatgaaaata tgcgtcaatt agtttcgtat gatggtaagc attttaaatt
     9661 aaataaaaca gataagacat atataaagga agaaattata aatattgcgg aaaatcaacc
     9721 tgaattattt tctaataatg tagtgacaag accattaatg gaagaatggt tatttaacac
     9781 ggtggcattt gttggaggac cgagtgaaat taagtactgg gctgaactaa aagatgtatt
     9841 tgaactattt gatgttgaaa tgcctatcgt gatgccaagg cttagaatta cttatttaaa
     9901 tgaccgtata gaaaaattac tttcgaaata caatattcca ttagaaaaag tgttagtcga
     9961 tggtgttgaa ggagaaagaa gtaagtttat tagagaacaa gcatcacatc aatttattga
    10021 aaaggtagaa ggtatgattg aacaacagcg tcgtctaaac caagacttat tagatgaagt
    10081 ggcggggaat caaaataata ttaaccttgt gaataaaaat aatgaaattc atatacaaca
    10141 gtatgattat ttgttaaaac gttatctttt aaacattgaa agagaaaacg agatcagtat
    10201 gaagcaattt agagaaattc aagaaacact ccatccaatg ggaggattac aagaaagaat
    10261 atggaatcca cttcaaattt tgaatgattt tgggacagat gtgttcaagc cctccaccta
    10321 tccaccactt tcttacactt ttgatcatat tattataaaa ccttaatata ccaagggttt
    10381 agcccgattt atcttaatga taaatcgggc atttttttgt tttttaaaat aaatttcaca
    10441 aattttgtat aaatagtggt ggatagtggg gagatgtggt aaattatata taaggtgagg
    10501 tgataaaaaa tgttcatggg agaatacgat catcaattag atacaaaagg acgtatgatt
    10561 ataccgtcca agtttcgtta tgacttaaat gagcgtttta ttatcacaag aggccttgat
    10621 aaatgtttat tcggttacac tctagacgaa tggcaacaga ttgaagagaa aatgaaaacc
    10681 ttacctatga caaaaaaaga cgcacgtaag tttatgcgta tgttcttctc tggtgctgtt
    10741 gaagtagaac ttgataagca agggcgtatt aacatccctc aaaacttgag gaaatacgct
    10801 aatttaacta aagaatgtac agtaatcggt gtttcaaatc gtattgagat ttgggataga
    10861 gaaacttgga atgatttcta tgaagaatct gaagaaagtt tcgaagatat tgctgaagat
    10921 ttaatagatt ttgattttta aaatggagga attgaagtgt ttcatcatat cagcgttatg
    10981 ttaaacgaaa ccattgatta tttaaatgta aaagaaaatg gtgtgtacat tgactgtacg
    11041 ctaggtggag cgggacatgc cctttattta ctaaatcaat taaatgacga cggaagatta
    11101 atagcaatcg atcaagacca aactgcaatt gataatgcta aagaggtatt gaaggatcat
    11161 ttgcataagg tgacttttgt tcatagcaac ttccgtgaat taactcaaat attaaaagac
    11221 ttaaacattg aaaaagtaga tggaatttat tacgacttgg gtgtttcaag cccacaactc
    11281 gacattccag aacgaggatt cagttatcac catgacgcaa cattagacat gcgtatggac
    11341 caaacacaag aactaacagc atatgaaatt gttaacaatt ggtcatatga agcgttagtg
    11401 aagatttttt atcgttatgg cgaggagaaa ttttcaaaac agatagctcg aagaatcgaa
    11461 gcacatcgtg aacaacaacc aataacaaca acattagaat tagttgacat tataaaagaa
    11521 ggtattcctg caaaagcaag aagaaaaggc ggacatcctg caaaacgagt atttcaagca
    11581 ctacgaattg cagtaaacga tgaattgtca gcttttgaag attcaataga acaagcgatt
    11641 gaattagtga aagtagacgg caggatatcg gtaatcactt tccattcttt agaagatcgt
    11701 ttatgtaaac aggtgttcca agaatatgaa aaaggtccag aggtaccaag aggattacca
    11761 gttataccag aagcatatac acctaagtta aagcgtgtta atcgtaaacc gattaccgct
    11821 acagaagaag atttagatga caataacaga gcacgaagcg cgaaattacg tgtagctgaa
    11881 atacttaaat aaggagcaat ttataatggc tgtagaaaaa gtgtaccaac catatgacga
    11941 acaagtttat aatagtatac cgaagcaaca accacaaact aagcccgaaa agaagactgt
    12001 ttcgagaaaa gtggttgtac aattaactaa atttgaaaaa gttttataca taactttgat
    12061 tactgtaatt gctatgttaa gtatttatat gctatcttta aaaatggatg cgtatgatac
    12121 gcgaggaaag attgcagatt tagattataa aatagataaa caatcaagtg aaaacagtgc
    12181 tttacaatct gaaatcaaaa agaattcttc ttatgaacgc atatacgaaa aggctaagaa
    12241 acaggggatg agccttgaga acgataatgt aaaggtagtg cgtagtaatg gcgaagcaaa
    12301 aaattaaaat taaaaaaaat aaaatagggg cagtcctact tgttggttta ttcggactgc
    12361 tcttttttat attggtttta agaatttcat atatcatgat tactggacat tctaatggtc
    12421 aagatttagt catgaaggca aatgaaaagt atttagttaa gaatgcacaa caaccagaac
    12481 gagggaagat atatgatcgt aatggtaaag tgctagcaga agatgtagaa agatataaac
    12541 ttgttgcagt aatagataaa aaggcgagtg ccaattctaa aaaacctagg catgtagttg
    12601 ataaaaaaga gactgcaaag aaattatcta cagtcattga tatgaagcca gaggaaattg
    12661 aaaagagact tagtcaaaag aaagctttcc aaattgaatt tggacgcaaa ggaacaaatt
    12721 taacgtatca ggacaaattg aaaatagaga aaatgaattt gcctggtatt tctttattgc
    12781 ctgaaacaga acgcttttat ccaaatggca attttgcatc acacttaatt ggtagagctc
    12841 agaaaaatcc agatactggt gaacttaaag gtgcgcttgg agttgaaaag atttttgata
    12901 gttatttaag tggatctaaa ggatcattga gatatattca tgatatttgg ggatatatcg
    12961 caccaaatac taaaaaagag aagcagccta aacgtggtga tgatgtccat ttaacaatcg
    13021 attcaaatat tcaagtattt gttgaagaag ctttagatgg catggttgaa agataccagc
    13081 cgaaagattt atttgcggtt gtcatggatg ccaaaactgg agaaatttta gcatacagtc
    13141 agcgaccaac atttaatcct gaaactggta aagactttgg taaaaagtgg gcaaatgacc
    13201 tatatcaaaa tacatacgag cctggatcaa catttaaatc atatgggtta gcagctgcta
    13261 ttcaagaagg tgcttttgat cctgataaga aatataaatc tggacataga gatattatgg
    13321 gttcacgtat ttcagactgg aatagagtcg gttggggtga aatcccaatg tcactcggat
    13381 ttacttattc atctaataca ttgatgatgc atttacaaga tttagttggt gcagacaaaa
    13441 tgaaatcttg gtatgaacga tttggatttg gaaaatcaac taaaggtatg tttgatggag
    13501 aagcacctgg tcaaattgga tggagtaatg agttgcaaca aaaaacgtca tcatttggtc
    13561 aatcgacaac tgtaacacct gttcaaatgt tacaagcgca atcagcgttc tttaatgatg
    13621 gtaatatgtt aaaaccatgg tttgtgaata gcgttgaaaa tcctgttagt aaaagacaat
    13681 tttataaagg tcaaaaacaa atcgcaggca aaccaataac aaaagatact gctgaaaaag
    13741 ttgaaaagca attggattta gttgtgaata gtaagaagag tcacgctgca aactatcgta
    13801 ttgatggtta tgaggtcgaa ggtaagactg gtacagcaca agtcgctgca cctaatggtg
    13861 gtggatacgt taaaggtcca aacccatatt ttgtaagttt tatgggtgac gcgccgaaga
    13921 aaaatcctaa agttattgta tacgctggta tgagcttggc acaaaaaaat gaccaagaag
    13981 cttatgaatt aggtgttagt aaagcgttta aaccaataat ggaaaatact ttgaaatatt
    14041 taaatgtagg taaatcaaaa gatgacacat ctaatgcaga gtatagtaaa gtgccagatg
    14101 ttgaaggtca agacaaacaa aaagctattg ataatgtgag tgcaaaatca ttagaaccag
    14161 ttactatcgg tactggcaca caaataaaag cacaatctat aaaagcaggg aataaagtct
    14221 tacctcatag taaagtactg ttattaacag atggagactt aactatgcct gacatgacag
    14281 gatggacgaa agaagatgtc attgcttttg aaaacctaac aaatattaaa gtaaatttaa
    14341 aaggtagcgg ttttgtgtcc caccaatcaa ttagtaaggg acaaaaactt actgaaaaag
    14401 ataaaataga cgtagaattt tcatcagaga atgtagacag caattcgacg aataattctg
    14461 attcgaattc agatgataag aagaaatctg acagtaaaac tgacaaggat aagtcggact
    14521 aacaagaatg gctacattaa ataagggtgt attgtcacta tttgttttta ctaaagtaat
    14581 gctgtgatag aaaacaacat cttcatttaa tctttataaa taagtgttga tagagaattt
    14641 taaggtagac gaggtcagat taacttgttt gttataggca aactttttat actggcctct
    14701 tatgccgtaa aaaagaaaaa ttataaattt tgattacaac tttgtttatt taattgaaaa
    14761 attgataata tattagtggt taaaaaagtc tggattaaga agaggagata gttatgattt
    14821 ttgtatatgc gttattagcg ctagtgatta catttgtttt ggtacctgtt ttaataccta
    14881 cattaaaaag gatgaaattt ggtcaaagta ttcgagaaga aggtccacaa agccatatga
    14941 agaagactgg tacaccaacg atgggtggac taacatttct attaagtatt gtgataacgt
    15001 ctttggtggc tattatattt gtagatcaag ctaatccaat catactgtta ttatttgtga
    15061 cgattggttt tgggttaatt ggttttatag atgattatat tattgttgtt aaaaagaata
    15121 accaaggttt aacaagtaaa cagaagtttt tggcgcaaat tggtattgcg attattttct
    15181 ttgttttaag taatgtgttt catttggtga atttttctac gagcatacat attccattta
    15241 cgaatgtagc aatcccacta tcatttgcat atgttatttt cattgttttt tggcaagtag
    15301 gtttttctaa tgcggtaaat ttaacagatg gtttagatgg attagcaact ggactgtcaa
    15361 ttatcggatt tacaatgtat gccatcatga gctttgtgtt aggagaaacg gcaattggta
    15421 ttttctgtat cattatgttg tttgcacttt taggattttt accatataac attaaccctg
    15481 ctaaagtgtt tatgggagat acaggtagct tagctttagg tggtatattt gctacgattt
    15541 caatcatgct taatcaggaa ttatcattaa tttttatagg tttagtattc gtaattgaaa
    15601 cattatccgt tatgttacaa gtcgctagct ttaaattgac tggaaagcgt atatttaaaa
    15661 tgagtccgat tcatcatcat tttgaattga taggatggag cgaatggaaa gtagttacag
    15721 tattttgggc cgttggtctg atttcaggtt taatcggttt atggattgga gtgcattaag
    15781 atgcttaatt atacagggtt agaaaataaa aatgtattag ttgtcggttt ggcaaaaagt
    15841 ggttatgaag cagctaaatt attaagtaaa ttaggtgcga atgtaactgt caatgatgga
    15901 aaagacttat cacaagatgc tcatgcaaaa gatttagaat ctatgggcat ttctgttgta
    15961 agtggaagtc atccattaac gttgcttgat aataatccaa taattgttaa aaatcctgga
    16021 ataccttata cagtatctat tattgatgaa gcagtgaaac gaggtttgaa aattttaaca
    16081 gaagttgagt taagttatct aatctctgaa gcaccaatca tagctgtaac gggtacaaat
    16141 ggtaaaacga cagttacttc tctaattgga gatatgttta aaaaaagtcg cttaactgga
    16201 agattatccg gcaatattgg ttatgttgca tctaaagtag cacaagaagt aaagcctaca
    16261 gattatttag ttacagagtt gtcgtcattc cagttacttg gaatcgaaaa gtataaacca
    16321 cacattgcta taattactaa catttattcg gcgcatcttg attaccatga aaatttagaa
    16381 aactatcaaa atgctaaaaa gcaaatatat aaaaatcaaa cggaagaaga ttatttgatt
    16441 tgtaattatc atcaaagaca agtgatagag tcggaagaat taaaagctaa gacattgtat
    16501 ttctcaactc aacaagaagt tgatggtatt tatattaaag atggttttat cgtttataaa
    16561 ggtgttcgta ttattaacac tgaagatcta gtattgcctg gtgaacataa tttagaaaat
    16621 atattagcag ctgtgcttgc ttgtatttta gctggtgtac ctattaaagc aattattgat
    16681 agtttaacta cattttcagg aatagagcat agattgcaat atgttggtac taatagaact
    16741 aataaatatt ataatgattc caaagcaaca aacacgctag caacacagtt tgccttaaat
    16801 tcatttaatc aaccaatcat ttggttatgt ggtggtttgg atcgagggaa tgaatttgac
    16861 gaactcattc cttatatgga aaatgttcgc gcgatggttg tattcggaca aacgaaagct
    16921 aagtttgcta aactaggtaa tagtcaaggg aaatcggtca ttgaagcgaa caatgtcgaa
    16981 gacgctgttg ataaagtaca agatattata gaaccaaatg atgttgtatt attgtcacct
    17041 gcttgtgcga gttgggatca atatagtact tttgaagagc gtggagagaa atttattgaa
    17101 agattccgtg cccatttacc atcttattaa agggtgtgag tattgatgga tgataaaacg
    17161 aagaacgatc aacaagaatc aaatgaagat aaagatgaat tagaattatt tacgaggaat
    17221 acatctaaga aaagacggca aagaaaaaga tcaaaggcta cacatttttc taatcaaaat
    17281 aaagatgata catctcaaca aactgatttt gatgaagaaa tttacttgat aaataaagac
    17341 ttcaaaaaag aagaaagcaa tgatgaaaat aatgattctg cttctagtca tgcgaataat
    17401 aataatatcg atgattctac agactctaat attgaaaatg aggattatag atataatcaa
    17461 gaaattgacg accaaaatga atcgaatgga attgcagtcg acaacgaaca acctcaatca
    17521 gctcctaaag aacaaaatag cgactcgaat gatgaggaaa cagtaacgaa aaaagaacga
    17581 aaaagtaaag taacacaatt aaagccatta acacttgaag aaaagcggaa gttaagacgt
    17641 aagcgacaaa aacgaatcca atacagtgtt attacaatat tggtattgtt gattgctgtt
    17701 atattaattt acatgttttc accacttagt aaaattgcgc atgtaaatat aaatggaaat
    17761 aatcacgtta gtacttcaaa gataaacaaa gttttaggtg ttaaaaatga ttcaaggatg
    17821 tatacgttta gtaaaaaaaa tgctattaat gatctcgaag aggatccatt aatcaaaagt
    17881 gttgagatac acaagcaatt accaaacaca ttaaacgtag atatcacaga aaatgaaatt
    17941 attgctttag tgaaatataa aggtaaatat ttacctttat tagaaaatgg taaattgctt
    18001 aaaggttcaa atgatgtcaa aattaatgat gcacctgtca tggatggttt caaaggtaca
    18061 aaagaagatg atatgattaa ggcgttatct gaaatgacac ctgaagttag acgatatatt
    18121 gccgaagtga catacgcccc aagtaaaaac aaacaaagca gaattgaatt gtttacgaca
    18181 gatggacttc aagtaatcgg tgatatttcg acgatatcta agaaaatgaa atattatccg
    18241 cagatgtcac aatcattatc aagggatagt tcgggtaaac taaaaacacg aggctatatt
    18301 gatttatcag tcggtgcttc atttatccca taccgtggaa acacgtctag tcaatcagaa
    18361 agcgataaaa atgtgactaa atcatctcaa gaggaaaatc aagcaaaaga agaattacaa
    18421 agcgttttaa acaaaattaa caaacaatca agtaagaata attaaaaaat tttgatattg
    18481 tctatgttta tagttcacaa gccattcaac gtattgtaaa ctaaggatag tgtatttttt
    18541 taatagtaat ttgtcaggag gtgcctatct atggaagaac attactacgt aagtattgat
    18601 attggatcat caagcgtaaa aacaatagta ggcgagaaat ttcacaatgg tataaatgtg
    18661 ataggtacag gacaaaccta cacgagcggt ataaaaaatg gtttaattga tgattttgat
    18721 attgcgcgac aagcaatcaa agacacaatt aaaaaggcat caatcgcttc gggtgttgat
    18781 attaaagaag ttttcctgaa attacctatc attggaacgg aagtttatga tgaatcaaat
    18841 gaaatcgact tttatgagga tacagaaatc aacggttcac atatcgaaaa agtattagaa
    18901 ggtattagag aaaaaaatga tgtgcaagaa acagaagtaa ttaatgtgtt cccgattcgt
    18961 tttatagtcg ataaagaaaa tgaggtttca gaccctaaag aattaattgc cagacattca
    19021 ttaaaggttg aagcaggcgt aattgctatt caaaaatcga ttttaattaa tatgattaaa
    19081 tgcgttgaag catgtggtgt tgatgtatta gatgtttact ctgatgcata taactatggt
    19141 tcaatcctaa cagctactga aaaagagtta ggtgcatgtg tcattgatat tggtgaagac
    19201 gttacgcaag ttgcttttta tgaacgcggt gaattagtag atgctgattc tatcgaaatg
    19261 gcagggcgtg atattacaga cgatattgca caaggattaa acacctctta tgaaactgct
    19321 gaaaaagtta aacaccaata tggtcatgca ttctatgatt ctgcttcaga tcaagatatc
    19381 ttcactgttg aacaggttga tagtgatgaa acagtacagt atactcaaaa agatttgagt
    19441 gactttattg aagcgcgtgt agaagaaata ttcttcgaag tatttgatgt tttacaagat
    19501 ttaggattaa caaaagtaaa tggtgggttt attgtaactg gtggatctgc aaacttactt
    19561 ggcgtaaaag aattattatc agatatggta agtgaaaaag ttagaattca cacgccatcg
    19621 caaatgggaa ttagaaaacc tgaattttct tcagcaattt ctacaatttc tagtagtatc
    19681 gcttttgatg agttattaga ttatgttaca attaattatc atgataatga agaaactgaa
    19741 gaagatgtta ttgatgtgaa agacaaagat aacgaatcta aattaggcgg atttgattgg
    19801 tttaaacgta aaacaaacaa aaaagatact catgaaaatg aagtagagtc aacagatgaa
    19861 gaaatttatc aatcagaaga taatcatcag gaacataaac agaatcatga acatgttcaa
    19921 gacaaagata aagaagaaag taaattcaaa aaactaatga aatctctatt tgaatgatta
    19981 ttggccaata aaactaggag gaaatttaaa tgttagaatt tgaacaagga tttaatcatt
    20041 tagcgacttt aaaggtcatt ggtgtaggtg gtggcggtaa caacgccgta aaccgaatga
    20101 ttgaccatgg aatgaataat gttgaattta tcgctatcaa cacagacggt caagctttaa
    20161 acttatctaa agctgaatct aaaatccaaa tcggtgaaaa attaacacgt ggtttaggag
    20221 caggagctaa tcctgaaatc ggtaaaaaag ctgcagagga atctcgtgaa caaattgaag
    20281 atgcaatcca aggtgcagac atggtatttg ttacttctgg tatgggtggc ggaactggta
    20341 ctggtgcagc accagtcgtt gctaaaattg caaaagaaat gggcgcatta actgttggtg
    20401 ttgtaactcg tccatttagt tttgaaggac gtaaacgtca aactcaagct gctgctggag
    20461 tagaagctat gaaagctgca gtagatacat taatcgttat accaaatgac cgtttattag
    20521 atatcgttga caaatctacg ccaatgatgg aagcatttaa agaagctgat aacgtgttac
    20581 gccaaggtgt acaaggtatc tcagacttaa tcgctgtttc tggtgaagta aacttagact
    20641 ttgcagacgt taagacaatt atgtctaacc aaggttctgc attaatgggt attggtgttt
    20701 cttctggtga aaatagagcg gtagaagctg ctaaaaaagc aatctcttct ccattacttg
    20761 aaacatctat cgttggtgca caaggtgtgc ttatgaatat tactggtggc gagtcattgt
    20821 cattatttga agcacaagag gctgctgata ttgtccaaga tgctgcagat gaagacgtta
    20881 atatgatttt cggtacagtt attaatcctg aattacaaga tgagattgtt gtaacagtta
    20941 ttgcaactgg ttttgatgac aaaccaacat cacatggtcg taaatctggt agcactggat
    21001 tcggaacaag cgtaaatact tctagcaatg caacttctaa agatgaatca ttcacttcaa
    21061 attcatcaaa tgcacaagca actgatagtg taagtgaaag aacacataca actaaagaag
    21121 atgatattcc tagcttcatt agaaatagag aagaaagacg ttcaagaaga acaagacgtt
    21181 aatcggttaa tatatataca caaataattc aacacaaatc atcagataac atatctgatg
    21241 atttttttac taatttttag aacatgtaga aggacattta agtttttcaa agttaataaa
    21301 agtgtttaag tatcgtgtca aaattaagtc aaaaattatt tgcgcaacat tttaacttta
    21361 aacataaatg ttatattata taattattaa ctttgtacag ttagacgaag ataatttaaa
    21421 tgaaatgatg gtgacgatcg agtgaatgat aattttaaaa agcaaccgca tcatttaata
    21481 tatgaagaat tattacaaca aggtattact ctaggtatta caactagagg cgatggttta
    21541 agtgactatc ctaaaaatgc ttttaatatg gcgagatata ttgatgatcg cccatataat
    21601 attactcaac atcaattgca attagctgaa gaaattgcgt ttgatagaaa aaattgggtg
    21661 tttcccatcc aaacacatga aaataaagtc gcttgtatta caaaggatga tataggcaca
    21721 aatatagaca ctttaactga tgcgcttcat ggtattgatg cgatgtacac atatgatagt
    21781 aatgtcttat taacgatgtg ttatgcagac tgtgtaccag tatattttta tagtacaaaa
    21841 catcatttta ttgcattggc gcatgcaggt tggcgtggta cctatactga aattgtaaaa
    21901 gaagtgctaa aacatgtgaa ctttgatttg aaagacttac atgtcgttat tggaccatct
    21961 acatcatcaa gttatgaaat taatgatgat attaaaaata aatttgaaac attgccaatt
    22021 gatagtgcca actatattga aactagagga cgagatcgtc atggtattga tttgaaaaaa
    22081 gccaatgctg aattattaaa ttattatggt gttcctaaag aaaatattta tacgacagcg
    22141 tatgctacat ctgaacattt agaattattt ttctcttatc gattagaaaa aggtcaaaca
    22201 ggacgcatgt tagcattcat tggtcaacag taaacaagga ggagatatgt ttgcgtgtga
    22261 aagataattt acaacaaatc tcaacacaaa ttaatgacaa aagtgaaaaa aataattttt
    22321 caacaaaacc aaacgtgatt gcagttacaa aatatgttac aatagagcga gctaaagaag
    22381 cgtatgaggc tggaataaga cattttggtg agaatagatt ggaaggcttt tttcaaaaga
    22441 aagaagcatt accatcagat gcggtgattc attttatagg atcattacaa tctcgaaaag
    22501 ttaaggacgt tataaacgac gtagattatt tccatgcttt agatcgattg agcttagcca
    22561 aagaaattaa caaacgtgca gaacataaaa ttaaatgttt cttgcaagtg aacgtttcgg
    22621 gagaagcttc taaacatggt attgctttag aagatgttga tcagtttata gatgatctta
    22681 aaaaatatga caaaatcgaa attgtaggtt taatgacgat ggcaccattg acagatgatg
    22741 aagcatatat tagatcgtta tttaaacagt tacgtttgaa aaaagaagaa atacaacgac
    22801 tcaatttaga atatgcgcct tgtgatgaat tatcaatggg aatgagtaat gactatctta
    22861 ttgcagttga agaaggtgcg acgtttgtta gaattgggac taaacttgta ggagaagagg
    22921 agtgagccac ttggctttaa aagatttatt tagtggattt tttgtaatag atgatgaaga
    22981 ggaagtagaa gtacctgaca aacaacaaca ggtcaatgaa gcgccagcaa aagagcagtc
    23041 acaacaaaca acaaaacaaa acgcaatcaa atcagtccct caaaaatctg catcaagata
    23101 tacaacaacg tcagaagaaa ggaataaccg tatgtctaat tattcaaaaa ataattcacg
    23161 taatgttgta actatgaaca atgctacacc aaacaatgca tcacaagaaa gttcaaaaat
    23221 gtgtttattc gaaccacgtg ttttctcaga tacacaagat attgctgatg agcttaaaaa
    23281 ccgccgtgcg acacttgtca atttacaacg tattgataaa gtatcagcga aaagaattat
    23341 tgatttttta agcggtactg tttatgcaat cggtggagat atccaacgtg taggtactga
    23401 tattttctta tgtacgcctg ataatgtgga agtagctgga agcattacag accatattga
    23461 aaatatggaa cattcattcg actaaggagt taacatatgg atataaatgt gctagctaca
    23521 atatttaaat ttatcctttt tgttgttgaa atttattatt tcggcatgat tatatatttc
    23581 tttacatctt gggtaccaag tattagagaa actaaggtag gttatttatt agcgaaaata
    23641 tatgaacctt tcttacaacc atttagaaaa gtaattccac ctattggaat tatcgacata
    23701 tcatcaatcg ctgcaattat cgttttagta ttattccaaa aagggttact ccaaatcttt
    23761 aattggattt taattcaatt acaataaatt aagcgacata acgaggcaag ggtacatgat
    23821 actttagcct cgtttttgat atgtattttt ctgaatataa gggcaataga tggtatttta
    23881 taaatttttt aaggtagtga ttaacataga tatttatcaa cactttaggc aggaagaata
    23941 cgaattaatt gatcagctaa cggataaatg tgatcaagcg gaacaccatt atgcaccagt
    24001 attaacgcat tttttagatc caagagggca atatatattg gaagtgattt gtggcagtta
    24061 tgaagattta aacgtatctt tttatggcgg gcctaatgct gaaagaaaaa gagcaatcat
    24121 ttcgccgaac tattatgaac ctaaagaaag tgactttgaa ttaactttaa tggaaataga
    24181 gtatcctgaa aaattcgtca ctttaaaaca tcaacatatt ttagggacat taatgtcttt
    24241 aggtatcgaa cgcgaacaag ttggagatat aattgtgaat caacgaattc aatttgtttt
    24301 gacaagtaga ttggaatcat ttattatgtt agaattacaa cgtattaaag gcgcatcagt
    24361 taaactttat actattccag taacagatat gatacaatct aatgagaatt ggaaaaatga
    24421 aagtgcaaca gttagttctt taaggttaga tgttgttatt aaagaaatga tacgtaaatc
    24481 acgtacgatt gcgaaacaac taatcgaaaa aaaacgtgtt aaagtgaatc acactattgt
    24541 tgattcagca gattttcaat tacaagcaaa tgatttaata tccatccaag gttttggtag
    24601 agcacacatt actgacttag gtggtaaaac taaaaaagat aaaacgcaca ttacctatag
    24661 aacattattc aaatagtaat gatttaagga ggataacaaa tgccttttac accaaatgaa
    24721 attaagaata aagagttttc acgtgtaaag aatggtttag aacctactga agttgctaat
    24781 tttttggagc aactaagcac tgaaattgaa cgtcttaaag aagataaaaa acaacttgaa
    24841 aaagtaatcg aagagagaga tactaatatt aagtcttatc aagacgtgca tcaatctgta
    24901 agtgatgctt tgatacaagc ccaaaaagct ggtgaagaaa ctaaacaagc tgcagagaaa
    24961 caagctgaag cgattatagc taaggcagaa gcgcaagcta atcaaatggt tggtgacgcg
    25021 gtagaaaaag cacgccgttt agcattccag actgaagata tgaaacgtca atcaaaagta
    25081 tttagatcgc gtttccgtat gttagttgaa gcgcaattag acttattaaa aaacgaagat
    25141 tgggattact tgttgaatta tgatttagac gctgaacaag tgacgcttga aaatattcat
    25201 catttgcatg aaaatgattt aaagccagat gaagttgcag caaatgcaca aaataatgca
    25261 tcaaatacac cagacaataa tcaacaatcc aatgattcag aaacaactaa gaagtaagaa
    25321 ttaaataaag acagacgcgt aatatacatt taacttttca cagcgaatta ggtaatggtg
    25381 agagcctagt aaaagcatgt atgttatatc actggctttt taatatttaa ataatgtaat
    25441 gagagaactc taagttgagt taataagggt ggtaccgcga gcaatcgtcc cttttaattt
    25501 aacttagagt tttttaaatt tttaaggagt gaaaaaaatg gattacaaag aaacgttatt
    25561 aatgcctaaa acagatttcc caatgcgagg tggtttacca aacaaggagc cgcaaattca
    25621 agaaaaatgg gatgcagaag atcaatacca taaagcgtta gaaaaaaata aaggtaacga
    25681 aacattcatt ttacatgatg gcccaccata cgcgaatggt aacttacata tgggacatgc
    25741 cttgaacaaa attttaaaag actttattgt acgttataaa actatgcaag ggttctatgc
    25801 accatacgta ccaggttggg atacacatgg tttaccaatt gaacaagcat taacgaaaaa
    25861 aggtgttgac cgaaagaaaa tgtcaacagc tgaattccgt gagaaatgta aagaatttgc
    25921 tttagaacaa attgaattac agaaaaaaga ttttagacgt ttaggtgttc gtggtaactt
    25981 taataatcca tatatcacat taaaacctga atacgaagct gcacaaattc gtatttttgg
    26041 agaaatggca gataaaggtt taatttataa aggtaaaaag ccagtttatt ggtctccttc
    26101 aagtgagtct tcattagcag aagcagaaat tgaatatcac gataaacgtt cagcatcaat
    26161 ttacgttgca tttgacgtta aagatgacaa aggtgtcgtt gatgcagatg ctaaatttat
    26221 tatctggaca acaacgccat ggacaattcc atcaaatgtt gcgattaccg ttcatcctga
    26281 attaaaatat ggtcaataca atgtaaatgg cgaaaaatat attattgcag aagccttatc
    26341 tgacgctgta gcagaagcac tggattggga taaagcatca atcaaattag aaaaagaata
    26401 cacaggtaaa gaattagagt atgttgtagc acaacatcca ttcttagaca gagaatcgtt
    26461 agtgattaat ggtgatcatg ttactacaga tgctggtaca ggttgtgtac atacagcacc
    26521 aggccacggg gaagatgact atattgttgg tcaaaaatat gaattaccag taattagtcc
    26581 aatcgatgat aaaggtgtat ttactgaaga aggcggccaa tttgaaggaa tgttctatga
    26641 caaagctaat aaagccgtta ctgatttatt aacagaaaaa ggtgcactat taaaattaga
    26701 ctttattaca catagctatc cacacgactg gagaacaaaa aaacctgtaa tcttccgtgc
    26761 tacaccacaa tggtttgctt caatcagtaa agtaagacaa gatattttag atgcaatcga
    26821 aaatacaaac ttcaaagtaa attggggtaa aacacgtatt tacaatatgg ttcgtgaccg
    26881 tggcgaatgg gttatttctc gtcaacgtgt ttggggtgta ccgttaccag tattttatgc
    26941 tgaaaatggc gaaattatca tgacgaaaga aacagtgaat catgttgctg atttatttgc
    27001 agaacacggt tcaaatattt ggtttgaaag agaagcgaaa gacttactac cagaaggatt
    27061 tacacatcca ggcagcccta acggtacatt tactaaagaa acagacatta tggacgtttg
    27121 gtttgattct ggttcatcac accgtggcgt gttggaaaca agaccggaat taagtttccc
    27181 agcagatatg tatttagaag gtagtgacca atatcgtggt tggttcaact cttctatcac
    27241 aacttcagtt gctacaagag gagtatcacc ttataaattc ttactttctc atggttttgt
    27301 tatggatggt gaaggtaaga aaatgagtaa atctttaggt aatgtgattg tacctgacca
    27361 agtggttaaa caaaaaggtg ctgatattgc gagactttgg gtaagtagta cggactattt
    27421 agctgatgtt agaatttctg atgaaatttt aaaacaaaca tctgatgttt atcgtaaaat
    27481 cagaaataca ttaagattta tgttaggtaa cattaacgat ttcaatcctg acacagatag
    27541 cattcctgaa tcagagttat tagaagtgga tcgttacttg ctaaatcgtt tacgtgaatt
    27601 tactgcaagt acgattaaca actatgaaaa ctttgactac ttaaatattt atcaagaagt
    27661 tcaaaacttt atcaatgttg agttaagtaa tttctatttg gattacggta aagacatttt
    27721 atatattgaa caacgtgatt ctcatatccg tcgcagtatg caaacagtgt tatatcaaat
    27781 tttagttgat atgacgaagt tgttagcacc aatcttagtg catacagctg aagaagtttg
    27841 gtctcataca ccacatgtta aagaagaaag tgttcactta gcagacatgc ctaaagttgt
    27901 agaagtagat caagctttat tggataaatg gcgtacattt atgaatttac gtgatgatgt
    27961 gaatcgtgca ttagaaactg ctcgtaatga aaaagttatt ggtaaatcat tagaagctaa
    28021 agttacgatt gctagtaacg ataaatttaa tgcatctgaa ttcttaactt catttgatgc
    28081 attacatcaa ttatttatcg tgtcacaagt taaagttgta gataagttag atgatcaggc
    28141 aacagcttat gaacatggtg atattgtcat cgaacatgca gatggtgaaa aatgtgaaag
    28201 atgttggaac tattcagagg atcttggtgc tgttgatgaa ttgacgcatc tatgtccacg
    28261 atgccaacaa gttgtaaaat cacttgtata attgaaattg tataaagtac tcatacagat
    28321 gatataaatt aaagctctct tcataatcat gttgtagttt ttgttgacat gatgaaggga
    28381 gtttttttac gaataaaaaa atgaccaagt tactggttat atgtgttaaa aaatgtgtaa
    28441 tttactaaaa taaaaattat tcaggaatgg tacaaattct ctaaggctta taaatgcgtt
    28501 atagttgcta ttctcaatta tgttcgcgat aattttaagt aaaagtaagc acagatattg
    28561 aatttgatag gagttaattg aatgtatcat aacagtaacg caaactttgt aaatggtatc
    28621 actttaaatg taagagataa gaatgaatta aagccatttt atgaggacgt attaggatta
    28681 aatattataa atgagacatt aacatcgata caatatgaag taggccaaaa taatcatgtc
    28741 attacacttg ttgaattaca aaatggacgt gaacctttaa tgtccgaagc gggactgttt
    28801 catatcgcaa ttaaactacc tcaaattagt gatttagcta atttactaat tcatttaagc
    28861 gaatatgata ttccagttaa cggtggtata cagcctgctt cgttatcatt attttttgaa
    28921 gacccggaag gaaacggttt taaattttat gttgataaag acgaagcgca atggacgagg
    28981 caaaatgatt tagtaaaaat tgatattaga ccattaaatg taccgagatt agtgagtcat
    29041 gcaacaaaat tgttatggtt aggtattcca gatgacgcta ttataggtgc attgcatatt
    29101 aagacaattc atttatcaga ggtaaaagag tactacctcg attattttgg attagagcaa
    29161 tcggcatata tggatgatta ttcaatattt ttagcatcga atggctatta tcaacatttg
    29221 gccatgaatg attgggtatc agcaacgaaa cgtgtagaaa attttgatac gtatggatta
    29281 gcaattgttg actttcatta tcttgaaaca acacatttaa atttacaagg tccggatggt
    29341 atctattatc gctttaatca tatcgaagtt gaaggttagt atatgctttg aatggacgaa
    29401 ccatataatg aatcgttttt aatgatcttt ttatacaagc tatgaaggag gctgggacat
    29461 aaatccctaa aaaacagcag taagataatt ttcaattaga aaatatctta ctgctgttct
    29521 ctatttatac aatacttcgt attgaatggc ttcgctttgc ccgtctggca cattactgta
    29581 aaattctata aatagaattt ttgatgacgg gtcccttcct agggtgccgt ctcagccacc
    29641 ccaaccggca cattgttgta agctgactat atgtcagctt ctgtgtgggg ccctgtcttc
    29701 gactggcact gctccctcag gagtctcgcc attaatacta cgtattaaca tgtaatttta
    29761 ctttgaaata ctttaaagcc caaattaatc aaaagctttc tgaaccagaa acgaaaaaaa
    29821 tctatagtta aagaaaaatt gatgtagagc ctgtttttgg atttatgaag gctattttgg
    29881 gtttcactag aatgtcagtt cgaggaataa ataaagttaa acgagagcta ggttttgtat
    29941 taatggtact taatataagg aaaatagcag ctcaacgagc tgtacattat aaaatacata
    30001 tcaaaaaagc tgatttctat caaataatta atagaaaaca gcttttttaa attgcctaag
    30061 aacttaatgt cccagcctgt ttcctaattt ttaatgtcat cttaaatatg ataaatgaat
    30121 aattaagttc atatttaatg tcaaaacata gtagtttatc aagtattgag ttagtaacat
    30181 tagatttaat gtaatatgct tacttttttt attagcaggt gtaagctata atataaagag
    30241 ttgtctcatg gacgattgat tggaggaacg aaaatgcaca aaaaatattt tattggcact
    30301 tccattttaa tagcagtatt tgtcgttata tttgaccaag ttactaaata tattatagct
    30361 actacaatga aaattggaga ttcatttgaa gtgataccgc actttttaaa cataacatca
    30421 catcgaaata atggtgctgc atggggaata ttgagtggaa aaatgacatt tttctttatt
    30481 attaccatta ttatattaat agccttagta tatttcttta ttaaagatgc tcaatataat
    30541 ttgtttatgc aagttgctat tagtttactt tttgcaggtg cacttggaaa ctttattgat
    30601 agaattttaa caggagaagt tgttgacttt attgatacaa atatttttgg ttatgatttt
    30661 ccaatattta atatcgcaga ttcaagttta acaattggtg taatattaat tattattgcc
    30721 ttattaaagg atacttccaa taaaaaggag aaggaggtta agtaatggag acttatgaat
    30781 ttaacattac agataaagaa caaacaggta tgcgtgtaga taagttgctg cctgaattaa
    30841 atagtgattg gtctcgtaac cagatacaag attggattaa agcaggttta gtcgttgcaa
    30901 acgataaagt tgttaaatct aattataaag tgaaacttaa tgatcatata gttgtcactg
    30961 aaaaagaagt ggttgaagct gatattctac ctgaaaattt aaatttagat atttattatg
    31021 aagatgacga tgttgcagtt gtatataaac cgaaaggcat ggtagttcat ccatcaccag
    31081 ggcattatac caatacatta gttaatggtt taatgtatca aattaaaaat ttgtcaggta
    31141 ttaatggaga aattcgtcca ggtattgttc accgtataga tatggatact tctggtttat
    31201 taatggttgc taaaaatgat attgctcatc gtgggcttgt agaacaatta atggataaat
    31261 ctgttaaaag aaaatatatc gctttagttc acgggaatat tcctcatgat tacggtacaa
    31321 tcgatgcgcc aattggtaga aacaaaaatg atcgtcaatc tatggctgtt gttgatgatg
    31381 gtaaggaagc agtgacacat tttaacgtac tagaacattt taaagattat acgcttgttg
    31441 aatgtcaact tgaaacagga cgtacgcatc aaatccgtgt gcacatgaaa tatattggct
    31501 tcccattagt tggtgatcca aagtatggac cgaaaaagac attggatatt ggtggtcaag
    31561 ctctacatgc tggacttatt ggattcgaac atccagtaac aggtgaatat attgaaagac
    31621 atgctgaatt accacaagac tttgaagatt tattagatac aattcgaaaa agagatgcat
    31681 aattgtgttg tgctataatt acgataacat tattatgtaa actataagta tttatcgttt
    31741 tcgttttttt aaaatgaaaa cacattataa aatagattaa ggttaacatt tttacttaga
    31801 tcggttaatt tttcaatata gattgacaaa gcgcctgatt agtattatcc ttataacagt
    31861 ttaagtacaa cataaagagt ctttaattga gcgtccagag agacgtcaaa gacatgaaaa
    31921 tatagatata tactaaaatg atcataacac tttcacatat gcaagaataa gtagtaatac
    31981 tacgattctt ctatgtatat aggctgattg tatatactaa acctcatgtc gatattaaag
    32041 acatgaggtt ttttgtttct aaattttgaa agggtgagaa tatgtctgaa cgtatcataa
    32101 tggatgatgc cgcaatacaa cgtacagtga cgagaatcgc tcatgaaatt ttggagtata
    32161 acaaaggtac tgataattta attcttttag gtatcaaaac aagaggtgaa tatttagcga
    32221 atcgtataca agataaaatt catcaaattg agcaacaacg tatacctact ggaacaattg
    32281 atattacata ctttagagat gatatagagc acatgtcatc acttacgaca aaagacgcaa
    32341 tagacatcga cacagatatt acagataaag tagtcatcat tattgacgat gtgctgtata
    32401 ctggtcgaac ggttcgtgct tcacttgatg ctattttgct aaatgctaga cctattaaaa
    32461 ttggtttagc tgctttggtt gatcgaggac atcgtgagtt accaattcga gcagattttg
    32521 ttggtaaaaa tatacctact tctaaagagg aaacggtaag tgtctattta gaagaaatgg
    32581 atcaaagaaa tgcagttata attaaataat acccctttta attcagtacg agagactgaa
    32641 aaaggtgggg gagttgaatg ataaataagt tttcatatgc ttgtttatct aataataccc
    32701 tcatgttcga caactataag tcaatttcta tggacgaaaa tgacttgtag caacttgtca
    32761 cactttttgt ctctttacat atactgatgt aaagagattt ttttattatc ggaggaaatg
    32821 aatattatgc aaaatgatga aatgtttgaa cgaacagtaa aacccgtact agatgtaaat
    32881 gaaaaaccac aaccagcgca atgggcattt ttaagcttac aacatttatt tgcgatgttt
    32941 ggcgcaacag tactagtacc attcttaaca ggactaccaa tatcagcagc gttactagct
    33001 tcgggaatcg gtacattact ttatatctta ataacgaagg cgcaaatacc agcatacttg
    33061 ggatctagct ttgcatttat cacaccaatt atcacgggat taagtacgca tagcttagga
    33121 gacatgcttg tagcattatt catgagtggt gttatgtacg tcatcatcgg aattctaatc
    33181 aaattaagtg ggacagcatg gttaatgaaa ttattaccac cagttgttgt tggaccagtc
    33241 atcatggtaa ttggtttaag cttagcgcct actgcagtca atatggcaat gtatgaaaat
    33301 cctggagata tgaaaggtta caatatcagt ttcttaattg ttgcaatgat aaccttgctt
    33361 gtaacaatag tcgttcaagg tttttttaaa ggattcctat ctttaattcc agttcttgta
    33421 ggtattatcg taggttatgt ggtagcgatt tttatgggga ttgtgaaatt tgatgcaatt
    33481 atgtcagcaa aatggataga tttccctcat atttatctgc catttaaaga ttatgtacct
    33541 tcatttcact taggacttgt acttgtaatg attccgattg tgttcgtaac agtaagtgaa
    33601 catattgggc accaaatggt actgaataaa atcgtaggta gaaacttctt tgaaaagcca
    33661 ggacttgata aatcaatcat tggtgatggt gtttctacaa tgtttgccag tattattggt
    33721 ggaccaccaa gtacaacata cggtgaaaat atcggtgtat tagcgattac cagaatatac
    33781 agtatttacg tcattggtgg tgcagcagtt atagcaattg ttttagcatt cattggtaag
    33841 ttcactgcat taatttcttc tatacctaca ccagttatgg gaggagtatc tatattactt
    33901 ttcggtatta ttgcagcaag tggcttaaga atgttagttg aaagcaaagt agattttgcg
    33961 aacaatcgaa atttagttat agcttcagta attttagttg taggtatcgg taatttagta
    34021 tttaacttaa aagaaattgg tatcaacttt caaattgagg ggatggcatt agctgcactt
    34081 tcaggaatta ttttgaactt aatcttacct aaagagaaaa aacaaaacaa ttaagattta
    34141 caaattaagg agggcgcttt tatgaatcat ttattatcaa tggaacattt atctacagat
    34201 caaatataca aacttatcca aaaggcaagt caatttaaat ctggtgaacg tcaactacca
    34261 aactttgaag ggaaatatgt cgcaaattta ttctttgaaa attctactcg aacaaaatgt
    34321 agttttgaaa tggcagaact taagctaggg ttaaaaacga ttagctttga aacatcaaca
    34381 tcatctgttt caaaaggtga atctttatat gacacatgta aaactttaga aagtattggc
    34441 tgtgatttat tagtcattag acatccgttt aataactact atgaaaaatt agcgaatatt
    34501 aacatcccaa ttgcgaatgc tggtgatggt agtggacaac atccaacaca aagtttactt
    34561 gatttaatga cgatatatga agaatatgga tattttgaag gcttgaatgt attgatttgt
    34621 ggagacatta aaaattcacg tgtcgcacgt agtaattacc atagtttaaa agcattaggt
    34681 gcaaacgtaa tgtttaatag cccaaatgct tggattgatg attctctaga agcaccttat
    34741 gtaaatatag atgatgttat agaaacagtg gatatagtta tgttattaag aattcaacat
    34801 gaaagacatg ggcttgcaga agaaactaga tttgcagcag atgattatca tcaaaagcat
    34861 ggcttaaatg aagtgcgcta taacaaatta caagaacatg ctattgttat gcatccggca
    34921 cctgtgaata gaggagtaga aatacaaagc gatttagtag aagcttcaaa atcaagaatt
    34981 tttaagcaaa tggaaaatgg cgtttactta agaatggcag tcattgatga attattaaaa
    35041 taggtaaggg gacgaaaatg atgaaattaa ttaaaaacgg taaagtatta caaaatggcg
    35101 aattacaaca agcagatatt ttaattgatg gtaaggtaat taaacaaatt gcacctgcaa
    35161 ttgaaccaag caatggtgtt gacatcatag atgcgaaagg tcactttgtg tcacctggat
    35221 ttgtcgatgt tcatgttcat ttacgcgaac ctggtggtga atataaagag acaattgaaa
    35281 ctggtactaa agctgctgct agaggcggat ttacaactgt atgtccaatg cctaacacaa
    35341 gaccggtacc agattctgta gaacattttg aagctttaca aaaattaatc gatgacaatg
    35401 ctcaagtacg tgtattacct tatgcttcaa ttacaacacg tcaattaggt aaagaattgg
    35461 ttgatttccc agcactagta aaagaaggtg cctttgcgtt tacagatgac ggtgtaggag
    35521 tacaaactgc aagcatgatg tatgaaggca tgattgaagc tgcaaaagta aacaaagcca
    35581 tcgtagcaca ctgtgaagat aattcattaa tctatggtgg tgcaatgcat gaagggaaac
    35641 gcagtaaaga gttaggtata ccaggtattc caaacatttg tgaatctgtt caaatcgcaa
    35701 gagatgtact attagctgaa gcagcaggtt gtcattatca tgtatgtcat gtttctacta
    35761 aagaaagtgt tagagtcatt cgtgacgcta aacgcgcagg tattcatgtt acagctgaag
    35821 ttacaccaca ccatttatta ttaacagaag atgatattcc tggtaacaat gccatttata
    35881 aaatgaatcc accattgaga agtactgaag atagagaggc tttgttagaa gggttactag
    35941 acggtacaat tgactgtatc gcaacagacc atgcaccaca tgcacgtgat gaaaaagcgc
    36001 aaccaatgga aaaagcacca ttcggaatag ttggtagtga aacagcattc ccattattat
    36061 atacgcattt tgtaaaaaat ggtgattgga cattacaaca attagtagat tacttaacaa
    36121 ttaaaccatg tgagacattt aatttagaat acggcacatt aaaagaaaat ggttatgcag
    36181 atttaacaat cattgattta gatagtgaac aagaaattaa aggagaagat ttcttatcaa
    36241 aagcagataa tacaccattt atcggctata aagtttatgg aaatccgatc ttaacaatgg
    36301 ttgaaggcga agttaaattt gagggggata aataatatgc aaagcaaacg ttatctagtg
    36361 ttagaagacg gttcttttta cgaaggctac cgtttaggat ctgataactt aactgtagga
    36421 gaaattgtat ttaatacagc gatgacaggt tatcaagaaa ctatttctga tccatcatat
    36481 acaggtcaga tcattacttt tacgtatcca ttaatcggta attatggtat caatagagac
    36541 gattttgaat cattagtacc tacattaaac ggtattgtag tgaaagaagc gagtgcgcat
    36601 ccaagtaatt ttagacagca aaagacactt catgacgttt tagaattgca tcaaattcca
    36661 gggattgcag gtgttgatac aagaagtatt acgcgtaaaa ttcgacaaca cggtgtgtta
    36721 aaagctggtt ttactgatcg aaaagaagat attgatcaac ttgtcaaaca tttacaacaa
    36781 gtagaattac ctaaaaacga ggtagaaatc gtttcgacta aaacaccgta tgtttcgaca
    36841 ggtaaggatc taagtgtcgt acttgtagac tttggtaaga agcaaaatat tgttcgagaa
    36901 ttaaacgtca gaggttgtaa cgtcacagtt gtaccatata caactactgc cgaagaaatt
    36961 ttagcaatgg ctccagatgg cgttatgcta tcaaacggac caggtaatcc tgaagttgta
    37021 gaatgtgcga ttccaatgat tcaaggaatt ttagggaaaa ttccgttctt tggtatctgt
    37081 ctaggacatc aactttttgc attatctcaa ggagcaagct catttaaaat gaagtttggt
    37141 catcgtggtg cgaaccatcc agttaaaaat ttagagactg gaaaagttga tattacgagt
    37201 caaaaccatg gatatgcaat agatatagat tcgttaaaaa gtactgattt agaagttact
    37261 catcttgcat taaatgatgg tactgtagaa ggtttaaaac ataaaacatt accagcattt
    37321 tctgttcaat accatcctga agcaaatcca ggaccgtcag attcaaacta tctatttgat
    37381 gattttgtag caatgatgac taattttaag gaaaaggagc gtcatatcaa tgcctaaacg
    37441 taatgatatc aaaacaattt tagtaatagg gtctgggcca attatcatag gtcaagcagc
    37501 tgaatttgat tatgctggaa cacaagcatg tctagcttta aaagaagagg gataccgagt
    37561 tattcttgta aattcaaatc cagcgacaat catgactgat aaggaaattg cggataaagt
    37621 atatatcgaa ccgttaactc atgattttat agcgcgaatt atacgtaaag agcaacctga
    37681 cgctttactt ccaactttag gtggtcaaac aggtttaaac atggcgattc aactacacga
    37741 aagtggtgtg cttcaagata ataacgtcca attattagga actgagctaa catcaattca
    37801 acaagcagaa gaccgtgaaa tgtttagaac attaatgaat gatttaaacg ttcctgtacc
    37861 agagagtgac attgtaaata cagtagagca agcctttaaa ttcaaagagc aagtgggata
    37921 cccgctaatt gttagaccgg catttacgat gggtggtacc ggaggcggta tttgtcataa
    37981 tgatgaagaa ttacatgaaa tcgtctcaaa tggtcttcat tatagtccag caacgcaatg
    38041 tttattagaa aaatctatcg caggttttaa agaaatcgaa tacgaagtaa tgcgtgataa
    38101 aaacgataat gccatcgttg tatgtaacat ggaaaatatt gatccagttg gtattcatac
    38161 aggcgattca attgttgtgg ctcctagcca aacattatca gatgttgagt atcaaatgtt
    38221 acgtgatgtt tcattaaaag ttattcgagc tttaggtatc gaaggtggtt gtaatgttca
    38281 attagcatta gatccccatt cattcgatta ttatattata gaagtaaatc cacgtgtatc
    38341 acgttcatca gcgttagctt caaaagcaac aggatatcct attgcaaaat tagctgctaa
    38401 aatcgcggtt ggtctaacat tagatgaaat gttaaatcca attacaggaa catcttatgc
    38461 agcgtttgaa ccaactttag actatgtgat ttcaaaaata ccaagatttc cttttgataa
    38521 atttgaaaaa ggagaacgag agcttggcac acaaatgaaa gcaacaggtg aagttatggc
    38581 cattggtcga acttacgaag aatcattgtt aaaagcaatt cgatcacttg agtatggtgt
    38641 gcatcactta ggattaccaa atggtgaaag cttcgatctt gattatatta aagaacgtat
    38701 ttcacaccaa gatgatgaac gattattttt catcggcgaa gcaattagaa gaggcacaac
    38761 attagaagaa attcataata tgactcagat tgattacttc ttcttacaca agttccaaaa
    38821 cattattgat attgagcatc aattaaaaga acatcaaggt gatttagaat atcttaaata
    38881 tgcaaaagat tatggattta gtgataaaac aatagcgcat cgctttaata tgacagaaga
    38941 agaagtatat caattgcgta tggaaaatga tattaaacct gtttacaaga tggttgatac
    39001 ttgcgcagct gaatttgaat cttcaacacc atattattat ggtacatacg aaactgaaaa
    39061 tgaatccata gttactgaca aagaaaaaat cttagtatta ggctctggac caattcgaat
    39121 cggccaaggt gtagaatttg actatgcgac agttcacgcc gtttgggcaa ttcaaaaagc
    39181 agggtacgaa gcgataattg tgaataacaa tccagaaaca gtttcaacag acttctcaat
    39241 ttctgacaaa ttatactttg aacctttaac tgaagaagat gtgatgaata tcattaattt
    39301 agaaaaacct aaaggtgtcg ttgtacaatt tggaggacaa acagcgatta atttagcaga
    39361 caaattggct aaacatggtg ttaaaatact tggtacttca ctagaaaatc taaatcgtgc
    39421 tgaagataga aaagaatttg aagcactatt aagaaaaatt aacgtgccac agccacaagg
    39481 gaaaacagct acatcacctg aggaagcatt agcgaatgct gcagaaatcg gatatccggt
    39541 tgtagtaaga ccttcttatg tattaggtgg tcgcgcaatg gaaattgtag acaatgacaa
    39601 agagttagaa aactatatga cccaggctgt aaaagcgagt ccggaacatc cggtactagt
    39661 cgatagatat ttaactggta aagaaattga agttgatgcg atttgtgatg gagaaacggt
    39721 cattattcca ggaatcatgg aacatattga acgtgctggt gtgcatagtg gtgactcaat
    39781 cgctgtatat ccgccacaaa ctttgacaga agacgagtta gcaacacttg aggactatac
    39841 tataaaatta gctaaaggtt taaacatcat tggcttaatc aacattcaat tcgttatagc
    39901 tcacgatggt gtgtatgttt tagaagtaaa tccacgttct agtagaacgg taccattctt
    39961 aagtaaaatt actgatattc caatggcaca attagctatg cgagcaatca ttggggaaaa
    40021 actaacagat atggggtatc aagaaggggt tcaaccatat gctgagggtg tatttgtgaa
    40081 agcaccggta tttagtttta ataaattgaa aaatgttgat attactttag gacctgaaat
    40141 gaagtctaca ggtgaagtaa tggggaaaga tactacatta gaaaaggcgt tattcaaagg
    40201 gttaacaggt agtggtgttg aagttaaaga tcacggtaca gtattaatga ccgtcagtga
    40261 caaagataaa gaggaagttg ttaaattggc acaacgctta aatgaagttg gctataaaat
    40321 tttagcaacg tctggaacag ctaataaatt agctgagtat gacatacctg cagaagtagt
    40381 aggcaaaatt ggtggcgaaa acgatttatt aacacgtatt caaaatggtg atgttcaaat
    40441 cgttataaat acaatgacta aaggtaaaga agtagaaaga gatggcttcc aaattagacg
    40501 tactacagtt gaaaatggta ttccatgttt gacatcttta gatacagcta atgccttaac
    40561 gaatgtaatt gaaagtatga catttacaat gcgtcaaatg taaatcaatc aaactgtatc
    40621 ggtggggctg taattaacca tttacttaaa gaagtttata ttacagcctc attattttaa
    40681 tgaattgctt aacgtaaagg gagacatata tgatgaaaga tttaccaatt attgcattag
    40741 attttgaatc aaaagaaaaa gtaaatcaat ttttagattt atttgatgaa tcattattcg
    40801 taaaagtagg tatggaactt ttttatcaag aaggccctca attaattaat gagataaaag
    40861 aaagaggcca tgatgtattt ttagatttaa agctgcatga tattcctaat acagttggta
    40921 aggcgatgga aagactagct aaattgaatg ttgatctggt aaatgttcat gctgctggtg
    40981 gtgtaaaaat gatgtctgag gccattaaag gattaagaaa acataatcaa catacaaaaa
    41041 ttattgcagt aacacagctt acgtcaacaa cagaagatat gttacgacac gaacaaaata
    41101 tacaaacatc gattgaagag gccgttttaa attatgccaa gttagcaaat gcagctggtt
    41161 tagatggcgt tgtttgttca cctcttgaaa gtcgtatgtt gactgaaaag ttaggtacat
    41221 catttttaaa agtaacacca ggtattagac ctaaaggtgc atctcaagat gaccaacacc
    41281 gtattacgac accggaagaa gcaagacagc ttggttcgac gcatattgta gtcggtagac
    41341 cgattacaca aagtgacaat ccagtcgaaa gttatcataa aattaaagaa agttggttag
    41401 tataatggct aaagaaattg caaaatcatt attagatatt gaagctgtaa cattatcacc
    41461 aaatgattta tatacatgga gttcaggtat taaatcaccg atttactgtg ataaccgtgt
    41521 tacgttaggt tatcctttag ttcgaggcgc aatccgcgat ggtttaatta acttaattaa
    41581 agaacacttt cctgaagtag aagttatttc tggtactgca acagctggta ttccacatgc
    41641 agcttttatt gctgaaaaat taaaattacc aatgaattat gttcgttcat caaataagag
    41701 tcatggtaag caaaatcaaa ttgaaggtgc taaaagtgaa ggtaaaaaag tagttgtgat
    41761 agaagattta atttcgacag ggggatcttc agtcacagca gttgaagcct taaaacaagc
    41821 aggtgcagaa gtattaggtg ttgtagctat ctttacttat ggtttgaaaa aagcagatga
    41881 tacatttagc aatattcaac taccttttta cactttaagt gattacaatg aattaattga
    41941 agtagctgaa aatgaaggta aaatttctag tgaagatatc caaacattag ttgaatggag
    42001 agacaactta gcataatata gacactagaa ggaggaattc aacatatgaa tgacaaaaca
    42061 tctaatgatt tatatgggaa gataaaacat tgtaacgaat ttatcaatca ttctaatgat
    42121 tccaatctat ctagtagtca cgatgtcgac gaaagttcaa cgaagcaaaa acatataaaa
    42181 aataaaacaa ctatagatca taatgatgat ttatttaaac atgtaaagga tatattacgt
    42241 aaacaaggac aaatttaaaa acaaaaaagc tatagtgttt aatatcatgg gctgcttaac
    42301 cgcatccgaa tattacaaac actatagctt ttattatata aaaaatttat tagcggataa
    42361 ttaactttat taaaatccaa ccaattaaga atacgagtaa taggactaat actggaatca
    42421 cataatgtaa cataacgtcc ctcctttaac ttaattttaa ttgtaatcaa atttgacaat
    42481 aagtcaaaac attaatacct atgataagta tcatttatta acatatgtat catattttta
    42541 atcttgcgta atttttatcg ttaactatgt gatttaatca acaggccaat aagacatttg
    42601 tcattcgtgc atataacggt acgacgcgct tttgtcattt taattatgtt aagataatag
    42661 tagttataga agttcaatct ataggaggca tagcatggat attccaaaaa tcacgacatt
    42721 tttaatgttt aataaccaag ctgaagaagc tgttaaacta tacacaagct tatttgaaga
    42781 tagtgagatt ataacaatgg ctaagtatgg tgaaaatgga cctggtgatc ctgggactgt
    42841 acaacactca atatttacat taaatggaca agtattcatg gcaattgatg ctaatagtgg
    42901 cacagaatta ccaatgaatc cagcgatttc attatttgtt acagtaaaag atactattga
    42961 aatggaacga ctatttaatg gattaaaaga tgaaggtgcc attttaatgc caaaaacgaa
    43021 tatgccacca tacagagagt ttgcttgggt tcaagataag tttggagtaa gttttcaatt
    43081 agcattacct gagtaaaagg attcgcacag cgttgaatga taaagaaaca ctttttctta
    43141 tgcatgcgtt ttacctatgt atttctattt taagtacaca ttagcatttt agtttcactc
    43201 atttttaaaa tcacaaagat aatttgtaac ttaaatgatg atacgttatt taaaaacacg
    43261 atacttcgtt tcaatgaacg cattaaataa taaataaaca cctcgcaaaa gaaagtagtc
    43321 ctttcttatg gtgaggtgtt tatttgtcga caacttgatt atgattgttt cattttttga
    43381 ataagttcat aatcaggtgt agcatacaaa gttttttgat tgtcatatgt tacaaaccca
    43441 ggctttgcac ctgatggttt gtgcacattt ttaattaacg tgtaatcaac aggtatttgt
    43501 ccagaattac cagcttttga aaaatatcct gctaacatag ccgcttcctt gattgtcgta
    43561 tcacttggtg cgtcattaaa tataacgaca tgtgaaccag gaatatcttt tgtgtgtaac
    43621 catgtgtgag tttttttagc ttttttattt gttaaataat cattttgctt gttattcttg
    43681 ccaacatata tatcgtcgcc atcagttgat acataatgtt gtaattgaat ctgcgctttc
    43741 tttttcttag tttgattttt acgctgtttc ataaagcctt gttctgctaa ttcatctcta
    43801 atttcatcaa tgtcatggac agaaatatga tgtaattgtt gttcgattgt tgaaaaataa
    43861 tctatattgt ctttcgtcaa ttgaatttga tgttgtaatt cacgttctct cgttttcata
    43921 cgattatatt gtttataata atattgagca tttgctgatg gggattttgt aggatttaaa
    43981 ggaatgacaa cttcttcatt cgtataataa ttcaacgccg tcacttcttt atcaccttgc
    44041 ttaattcgat atatattagc agtgatcaat tcaccatata actgttcagt atctttattt
    44101 ttagactgct catattcttc aatcaacttc gctaatttat tttgatattt gtgcaactgc
    44161 tgttgaacaa atcgaactaa atcattcgca cgttgtttaa cgcgttcacg ttcgccacgc
    44221 gcatcataaa aacgatcaag taaatcattt aatgaatcgt acgtaactgt atcatcatta
    44281 aattgattta actttataaa atagaaatcc tctttacctg tttcatgatt tttatgaaaa
    44341 ataggagtag gtggtaactt ggtttctgcc ataacttcgt cgaatgcttc tggtaatgtt
    44401 gatgaagtca taaattgacg acgattaacg atttcattcg taattaaagg gctaaatcct
    44461 tcaaactgat tcaataattg tttagcaata ttacctgcgt taaaatcgat atatttcaac
    44521 acctctgcac ctgtaatatc atacggattc attttgtgct gagtaggtgg tgcttcataa
    44581 ttaaatcctg gcattactgt acgatagtga ttcgtatttg gtgttaagtg tttaaatcct
    44641 tcaattattt tgcgattttc atctactaaa attaagttac tatgtttacc cataatctct
    44701 aggataacag tgcggtaaat agtatcgcca atttcatctt tactctttat atcgatttca
    44761 atgcgacgat cattaccaat ttgcttaatc gattcgataa taccaccttc taagtgtttt
    44821 ctaaaaacac gcgcaaacat gggtggatta aatggattat catatttttt agtagtcaat
    44881 tgtaatcttg aaaagtttgg atggattgac aataacaatt gatggttttg tctattttga
    44941 cgtacaacca ttagtatcgt gtcattatca ggttgattga ttttgtgaac gcgtcctgtt
    45001 gttaaaaatt gtagagactc aaccattttc tttgtaaata agccatcata agccataatt
    45061 tatcttccac cttcttcata tcattcgttt cattttaaca tgattgtaac ttttcggtat
    45121 agttattgaa ccatacatta tgccacacat tttacattat ctaaaagttt gcaattcaat
    45181 ttatttaatt aaaattaatc gtgcaatata acgatattgt tagacttaat agaaattatg
    45241 gcatgcaatt tcaaatatgc tatacaatat aaagaacaat gtgatatcat atttaaataa
    45301 tagaagatta gcttagagag gtcgtaaggc atggataatg aaaaaggatt gttaatcgtt
    45361 ttatcaggac catctggagt aggtaaaggt actgttagaa aacgaatatt tgaagatcca
    45421 agtacatcat ataagtattc tatttcaatg acaacacgtc aaatgcgtga aggtgaagtt
    45481 gatggcgtag attacttttt taaaactagg gatgcgtttg aagctttaat caaagatgac
    45541 caatttatag aatatgctga atatgtaggc aactattatg gtacaccagt tcaatatgtt
    45601 aaagatacaa tggacgaagg tcatgatgta tttttagaaa ttgaagtaga aggtgcaaag
    45661 caagttagaa agaaatttcc agatgcatta tttattttct tagcacctcc aagtttagat
    45721 cacttgagag agcgattagt aggtagagga acagaatccg atgagaaaat acaaagtcgt
    45781 attaacgaag cacgtaaaga agtcgaaatg atgaatttat acgattacgt tgtagttaat
    45841 gatgaagtag aacttgcgaa gaatagaatt caatgtattg tagaagctga gcacttaaaa
    45901 agagagcgcg tagaagctaa gtatagaaaa atgattttgg aggctaaaaa ataatgttaa
    45961 atccaccatt aaaccaatta acgtcacaaa ttaaatcaaa gtatttaatt gcaacaactg
    46021 cagcgaaaag agcgcgtgaa attgatgaac aacctgaaac tgaattatta agtgaatatc
    46081 attcatttaa accagttggt agagcgttag aagaaattgc tgacggtaaa attcgccctg
    46141 ttatttcaag cgattattat ggtaaagaat agtttcgacc attaaaaata tgtgaagcta
    46201 gacgtacatc aaatacgtca aggcatatcc aaatcaaacg cacctatgta ggtgtgtttt
    46261 tttagtttat ccaatgattg atgttataat aatactaaat ttgtatctat aaaaaagtaa
    46321 tgagcatttg tgcgcatatg atgatgtaaa gcgtaaatgt catagtgata tttaagggag
    46381 attaaatatg aagaaaatat tattagccgt tacaggtggc attgcggcat ataaagcaat
    46441 tgatttgaca agtaagttaa cacaatctgg gtatgaagtt cgcgttatgt taacgaatca
    46501 cgcacaaaaa tttgtgacac cattagcatt tcaagcaata agtcgaaatg ctgtttatac
    46561 agatactttt atagaagaaa atccttcaga aatacagcat attgcattag gtgattgggc
    46621 agatgcaatc attgttgcac ctgcaacggc aaatacaatt gcaaaattga gtgtaggtat
    46681 tgctgatgat ttggtgacat caacgttgct agcaacagag acaccgaaat ttattgcgcc
    46741 tgctatgaat gtgcatatgt atgaaaataa acgtacgcag caaaatatta atattttaaa
    46801 agaagatggg tatcatttta tcgaaccagg aagcggattt ctagcatgtg gttatgttgc
    46861 taaaggacgt atggaagaac cgcttcaaat cgtttctgtt attgatgctc attttcaaaa
    46921 tagtaatcgt ttagctaata gttcatttca agataaacgc gcattggtta cagcaggacc
    46981 aactattgaa gttatcgatc cagtcagatt tgtatccaat cgttcttctg gaaaaatggg
    47041 ctatgcaata gctgaagcat tgcgaaatcg aggagctatc gtgacgttag ttgctggtcc
    47101 tacaacacta gaggatccaa aagatattga agttattcat gttcaaagtg ctgaagaaat
    47161 gtttgaacaa gtgacaagcc gatttgacga acaagatatt gttgtaaaag cagcagccgt
    47221 atctgactat acaccagttg atgtattaga acataagatg aaaaagcagg atggtgattt
    47281 atcagtatct tttaaacgta ctaaagacat tcttaaatat ttaggtgaac ataaaacatc
    47341 acagtattta ataggctttg cagcagagac tgaagatatt gaaaattatg cacaacaaaa
    47401 attacgcaag aaaaatgcag atgtgattat ttcaaataat gttggggata tgtctatcgg
    47461 atttagttct gatgataatg aattgacaat gcattttaaa aataatgaaa aggtaaatat
    47521 caagaaagga aaaaaagtag tattagctgc acaaatttta gatgaactag aaactaggtg
    47581 gcaataatga tagcgaaagt catagtcgat gtcgcgtcga agagcgttga ctttaaattt
    47641 gattatataa ttcctgaaca actcgaatct gtcatccaac ctggtgtgcg tgtgattgta
    47701 ccttttggac caagaacgat tcaaggttat gtaatggaag taacagcaga acctgatgca
    47761 caacttgacg tttcgaagtt aaaaaaaatc atagaagtga aagatataca acctgaatta
    47821 acatcagaat taatagcttt aagtgagtgg atgggttcaa ctcatgtcat taaacgtatt
    47881 tctatgctag aagtgatgct tccgagtgct attaaagcga agtataaaaa agcatttaag
    47941 atgaaagatg acatagagct accttcagct ttattacaaa aatttgataa gcatggttac
    48001 tattattata aagatgcgca aaaaaataat gatattcaat tgcttatgaa gttgttaaaa
    48061 gatgatatcg ttgaagaaaa aacgattctc acacaaaata taactaaaaa aaccaagcgt
    48121 gctgttcgtg tcattgaagg gtatcatcct gatgaagtat tagctaagtt ggagaaagtt
    48181 attaaacaat acgatttgta tgcttacttg tctgaagaac aacataaaac aatattttta
    48241 actgatattg aggatatggg cttttcaaaa tccagtttag atggacttat caaaaaaggt
    48301 tatgttgaaa aatatgacgc ggttgttgat agagacccat ttaaagatcg tgttttcgaa
    48361 caagaatcaa aacagcaatt aacagaagat caatataaag catatgaagc gattaaagct
    48421 aaaattgtaa gccaagagca agaaacattt ttacttcatg gtgtgacggg atcaggtaaa
    48481 acagaagtat atttacaaac gatagaagat gttttaagcc aaggaaaaca ggcgatgatg
    48541 ttagttcctg aaatcgctct aacaccgcaa atggttttac gcttcaaacg tcgatttggt
    48601 gatgacgttg ctgtattaca ttctggctta tctaatgggg aacgttatga tgagtggcaa
    48661 aaaattaggg atggtcgtgc gagagtaagt gttggtgcaa ggtcaagtgt gttcgcacct
    48721 ttcaaaaatt tagggttaat catcattgat gaagaacatg aatctacata taaacaagaa
    48781 gattatccga gatatcacgc tagagaaatt gcccaatggc gaagtgaata tcatcactgt
    48841 ccagtcattt taggaagtgc aacaccatgt cttgaaagtt atgcacgagc tgaaaaaggc
    48901 gtttatcatt tgctatcatt accaaacaga gtgaaccaac aagctttacc tgaaattgat
    48961 atagtagaca tgcgtgaaga attgagtgaa ggtaatcggt caatgttttc aaaagattta
    49021 cgtgaagcca tacaattaag attagatcga caggaacaag ttgttttatt tttaaatcga
    49081 cgtggttatg catcgtttat gttatgtcgg gattgtggat atgtaccgca atgtccaaac
    49141 tgtgatattt cattaacgta tcataaaacg acagacttat taaaatgtca ctattgtggt
    49201 taccaagaga cgccaccgaa tcaatgtcca aattgtgaga gtgaacacat tcgacaagta
    49261 ggtactggta ctcagaaagt tgaagaacta ttgcaacaag aatttgaaga tgcgcgcata
    49321 attaggatgg atgtagatac aacctcaaag aaaggtgcac atgaaaagtt attgactgaa
    49381 ttcgaaaaag gtaacggtga cattttacta ggtactcaga tgattgcgaa aggattagat
    49441 tatccaaata ttactttagt tggtgtgctg aatgcagata caatgttaaa tttacctgat
    49501 tttcgggcga gcgaacgtac ttatcaacta ttaacgcaag tggctggtag agctggtcgt
    49561 catgaaaagg caggtcaagt catcattcaa acgtataatc cagatcatta ttcaatattg
    49621 gatgttcaaa aaaatgatta tttaacattt tatcgtcagg aaatggaata tcgtaaatta
    49681 ggaaagtatc caccgtatta ttatttgatt aatttcacaa tctcacataa agaaatgaag
    49741 aaggttatgg aagcatcgca gcatgttcat aaaattttat tacagcattt aacagaaaaa
    49801 gcgcttgtgc taggtccatc tccggcagca cttgtgagaa tcaacaatga atttagattc
    49861 caaattttag tgaaatataa aagtgaacct ggattattac aagccattca gtttttagat
    49921 gactattacc atgaaaaatt tataaaagaa aaattagcat tgaagattga tattgatccg
    49981 cagatgatga tgtaacatta ctaattatta gaaacaagtt cagtatgtac gagtatttga
    50041 accagtgttt gaatatttac tttaagtaca gaataagggc agaatataca actgttaact
    50101 atttaaatta gcagtttata ttctgtcttt ttatatggct ttataactta cgtgattttg
    50161 gtttgataag gaatttatta gtattttcat ttacgaattc tgattttaat gcaagcgcca
    50221 tacttactga tgaataaaag tactaatgat taagcaaact atttttaa
//
LOCUS       DAPSKH010000011        49668 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPSKH010000011 DAPSKH010000000
VERSION     DAPSKH010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 49668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49668
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.011"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            5..119
                     /gene="rrf"
                     /locus_tag="RPH49_000753"
     rRNA            5..119
                     /gene="rrf"
                     /locus_tag="RPH49_000753"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(831..2213)
                     /locus_tag="RPH49_000754"
     CDS             complement(831..2213)
                     /locus_tag="RPH49_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDY5123940.1"
                     /translation="MKNTLYHQLYEKLKKQIIEGQFKEGDKFYSKRQLSKHLSISQTT
                     VEHAYQLLLDEGYIYSRPRSGYFVSEIESLTILNNQPIPSLFDDDSYKPKASDEAYDY
                     AFNLDEIDTKHFPIELFRKYSKDLYDTNHLNQLRRGHFQGELHLRFQLAFYLFTNRGV
                     ICDPNQIIIGSSTEQLVNQLVDLLYTSTFIIEKPSYPPIKNILDKKQVEYEQIEVEDN
                     GINVDEVIKSQKNIVYITPSHQFPTGYVMDLKKRTQLIQWAQEKEERFIIEDDYDSEF
                     RYFGKPIPAIQGLYSRGEKVIYISTFSKSIFPSCRVAYMVLPYSIMKKYHSQNHIEGN
                     TVPVHMQNLIATFISSGGFERHLNKMRRIYRRKLTYILKRLKPYKEQLDIQGAETGMH
                     FTITVKNGLTLQECLDRANKVKLKLQVYNFDDDQDYKKTPKFILGFGGIDDDALKPHV
                     DALIKTLIIK"
     gene            2317..3204
                     /gene="pdxS"
                     /locus_tag="RPH49_000755"
     CDS             2317..3204
                     /gene="pdxS"
                     /locus_tag="RPH49_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011303857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HDY5123941.1"
                     /translation="MSKIIGSDRVKRGMAEMQKGGVIMDVVNAEQARIAEEAGAVAVM
                     ALERVPSDIRAAGGVARMANPKIVEEVMNAVSIPVMAKARIGHITEARVLEAMGVDYI
                     DESEVLTPADEEYHLRKDQFTVPFVCGCRNLGEAARRIGEGAAMLRTKGEPGTGNIVE
                     AVRHMRQVNSEVSRLTVMNDDEIMTFAKDIGAPYEILKQIKDNGRLPVVNFAAGGVAT
                     PQDAALMMELGADGVFVGSGIFKSEDPEKFAKAIVQATTHYQDYELIGRLASELGTAM
                     KGLDINQLSLEERMQERGW"
     gene            3208..3768
                     /gene="pdxT"
                     /locus_tag="RPH49_000756"
     CDS             3208..3768
                     /gene="pdxT"
                     /locus_tag="RPH49_000756"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HDY5123942.1"
                     /translation="MKIGVLALQGAVREHIRHIELSGHEGIAVKKVEQLEEIEGLILP
                     GGESTTLRRLMNLYGFKEALQNSTLPMFGTCAGLIVLAQDIVGEEGYLNKLNITVQRN
                     SFGRQVDSFETELDIKGIATDIEGVFIRAPHIEKVGQGVNILCKVNEKIVAVQQGKYL
                     GVSFHPELTDDYRVTDYFINHIVKKA"
     gene            complement(3976..5190)
                     /locus_tag="RPH49_000757"
     CDS             complement(3976..5190)
                     /locus_tag="RPH49_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDY5123943.1"
                     /translation="MHILIGIIGIIFFLALAFLFSSDRKNIRWKYVGILLAIQLIFAF
                     ILLKTTMGIKVIGGISNGFNYLLLKAADGVNFVFGGIQYIDPKQPPFFFSVLLPIVFI
                     SAIIGILQYTKILPLIINVLGFLISKINGMGRLESYNAVAAAILGQSEVFISIKKQLP
                     YIPKQRLYTLTASAMSTVSASIIGAYFTLIEPKYVVTAVVLNLFGGFIIASIINPYKV
                     NEEDDKLLVEETEERQQSFFEMLGEYILDGFKVAVIVGAMLIGYIAIIALLNGIVSNI
                     FSTVSGGAISWDFQTLIGFVFAPFAFLVGVPWQDAVQAGSVMATKLLSNEFVAMQALG
                     KLSDLSEHAKGVTSVFLVSFANFSSIGIISGAIKSLNDKKGDTVARFGLKLLFGATLV
                     SFISAAIAGFFI"
     gene            5348..5809
                     /locus_tag="RPH49_000758"
     CDS             5348..5809
                     /locus_tag="RPH49_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000551761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDY5123944.1"
                     /translation="MHNMSDIIEQYIKRLFEESNEDVVEIQRANIAQRFDCVPSQLNY
                     VIKTRFTNEHGYEIESKRGGGGYIRITKIENKDATGYINHLLQLIGPSISQQQAYYII
                     DGLLDKMLINEREAKMIQAVIDRETLSMDMVSRDIIRANILKRLLPVINYY"
     gene            5828..6394
                     /locus_tag="RPH49_000759"
     CDS             5828..6394
                     /locus_tag="RPH49_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrB/UvrC motif-containing protein"
                     /protein_id="HDY5123945.1"
                     /translation="MLCENCQLNEAELKVKVTSKNKTEEKMVCQTCAEGHHPWNQANE
                     QPEYQEHQDNFEEAFVVKQILQHLATKHGINFQEVAFKEEKRCPSCHMTLKDIAHVGK
                     FGCANCYATFKDDIIDIVRRVQGGQFEHVGKTPHSSHKKIALKRKIEEKNEYLKKLIE
                     IQDFEEAAIVRDEIKALKAESEVQHDDA"
     gene            6384..7391
                     /locus_tag="RPH49_000760"
     CDS             6384..7391
                     /locus_tag="RPH49_000760"
                     /EC_number="2.7.14.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein arginine kinase"
                     /protein_id="HDY5123946.1"
                     /translation="MTHNIHDNISQWMKSNEETPIVMSSRIRLARNLENHVHPLMYAT
                     ENDGFRVINEVQDALPNFELMRLDQMDQQSKMKMVAKHLISPELIKQPAAAVLVNDDE
                     SLSVMINEEDHIRIQAMGTDTTLQALYNQASSIDDELDKSLDISYDEQLGYLTTCPTN
                     IGTGMRASVMLHLPGLSIMKRMTRIAQTINRFGYTIRGIYGEGSQVYGHTYQVSNQLT
                     LGKSELEIIETLTEVVNQIIHEEKQIRQKLDTYNQLETQDRVFRSLGILQNCRMITME
                     EASYRLSEVKLGIDLNYIELQNFKFNELMVAIQSPFLLDEEDDKSVKEKRADILREHI
                     K"
     gene            7405..9861
                     /locus_tag="RPH49_000761"
     CDS             7405..9861
                     /locus_tag="RPH49_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDY5123947.1"
                     /translation="MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEG
                     IAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNF
                     VGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
                     PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIA
                     EGLAQAIVNNEVPETLKDKRVMSLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVIL
                     FIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEYRKNIEKDAALERRF
                     QPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAI
                     DLIDEASSKVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLE
                     KQYEEAKNEWKNAQNGMSTSLSEEDIAEVIAGWTGIPLTKINETESEKLLSLEDTLHE
                     RVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAESMFGDD
                     DAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHP
                     DVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDY
                     ETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELKEIVTMMVNKLTNRLSEQNIN
                     IIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDG
                     KEFKYDIAEQTSETKTPSQA"
     gene            10346..11710
                     /gene="radA"
                     /locus_tag="RPH49_000762"
     CDS             10346..11710
                     /gene="radA"
                     /locus_tag="RPH49_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDY5123948.1"
                     /translation="MAKKKVIFECMACGYQSPKWMGKCPNCGAWNQMEEIVEKAANPK
                     HGVKTKELAGKVQKLNSIKHETTPRVLTDSAEFNRVLGGGIVSGSLVLIGGDPGIGKS
                     TLLLQICASLSQKKKVLYITGEESLSQTKLRAERLDEDSSELQVLAETDLEVIYQTVK
                     EEQPDLLVVDSIQTIYHPEISSAPGSVSQVRESTQSLMNIAKQMNIATFIVGHVTKEG
                     QIAGPRLLEHMVDTVLYFEGDEHHAYRILRAVKNRFGSTNEMGIFEMKQSGLKGVNNP
                     SEMFLEERSTNVPGSTIVATMEGTRPLLIEVQALVTPTTFNNPRRMATGIDHNRLSLL
                     MAVLEKKENYLLQQQDAYIKVAGGVKLTEPAVDLSVIVATASSFKDEAVDGLDCYIGE
                     VGLTGEVRRVSRIEQRVQEAAKLGFKRVIIPKNNIGGWTYPEGIQVIGVTTVHEALSF
                     ALHS"
     gene            11735..12808
                     /locus_tag="RPH49_000763"
     CDS             11735..12808
                     /locus_tag="RPH49_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017328539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDY5123949.1"
                     /translation="MNIVKLMVIIIYLIIGSALGIIIIPEIANDLGLQNSSFLKNHYV
                     DGIIGSIFMFLIFGVFIRRVTNAIKGLEHFIMRRSAVEILFATIGLIIGLLISVMVSF
                     ILESIGNSIFNHFIPVIITILLCYFGFQFGLKKRDEMLMFLPENIARSMSQHTKSATP
                     KIIDTSAIIDGRILEVIRCGFIDGNILIPQGVINELQIVADSNDSVKREKGKRGLDIL
                     NELYDLDYPTKVIHPTKTHSDIDTMLLKLAKQYHASIITTDFNLNKVCHVHGIKALNV
                     NDLSEAIKPNVHQGDQLHILLTKMGKEPGQAVGYLDDGTMVVVDNAKNLIGSHVNLEV
                     VSLLQTSSGRIVFAKKIEDTVSL"
     gene            13365..14819
                     /locus_tag="RPH49_000764"
     CDS             13365..14819
                     /locus_tag="RPH49_000764"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDY5123950.1"
                     /translation="MSDRIRVRYAPSPTGYLHIGNARTALFNYLYAKHYNGDFVIRIE
                     DTDKKRNLEDGETSQFDNLKWLGLDWDESVDKDNGYGPYRQSERQHIYQPLIDQLLAE
                     DKAYKCYMTEEELEAEREAQIARGEMPRYGGQHAHLTEEQRQQFEAEGRQPSIRFRVP
                     QNQTYSFDDMVKGNISFDSNGIGDWVIVKKDGIPTYNFAVAIDDHYMQISDVIRGDDH
                     ISNTPKQIMIYEAFGWEPPRFGHMSLIVNEERKKLSKRDGQILQFIEQYRDLGYLPEA
                     LFNFIALLGWSPEGEEEIFSKEEFIKIFDEKRLSKSPAFFDKQKLAWVNNQYMKQKDT
                     ETVFQLALPHLIKANLIPEVPSEEDLSWGRKLIALYQKEMSYAGEIVPLSEMFFKEMP
                     ALGEEEQQVINGEQVPELMTHLFSKLEVLEPFEAAEIKKTIKEVQKETGIKGKQLFMP
                     IRVAVTGQMHGPELPNTIEVLGKEKVLNRLKQYK"
     gene            15242..15889
                     /gene="cysE"
                     /locus_tag="RPH49_000765"
     CDS             15242..15889
                     /gene="cysE"
                     /locus_tag="RPH49_000765"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDY5123951.1"
                     /translation="MILLKRMRDDIKMVFEQDPAARSTLEVITTYAGLHAVWSHLIAH
                     KLYNQKKYVAARAISQISRFFTGIEIHPGAKIGKRLFIDHGMGVVIGETCTIGDNVTI
                     YQGVTLGGTGKERGKRHPDIGDNVLIAAGAKVLGNIKINSNVNIGANSVVLQSVPSYS
                     TVVGIPGHIVKQDGVRVGKTFDHRHLPDPIYEQIKHLERQLEKTRNGEIQDDYII"
     gene            15873..17273
                     /locus_tag="RPH49_000766"
     CDS             15873..17273
                     /locus_tag="RPH49_000766"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDY5123952.1"
                     /translation="MITLYNTLTRQKEVFKPIEPGKVKMYVCGPTVYNYIHIGNARPA
                     INYDVVRRYFEYQGYNVEYVSNFTDVDDKLIKRSQELNQSVPEIAEKYIAAFHEDVGA
                     LNVRKATSNPRVMDHMDDIIQFIKDLVDQGYAYESGGDVYFRTRKFEGYGKLSHQSID
                     DLKVGARIDAGEHKEDALDFTLWKKAKPGEISWDSPFGEGRPGWHIECSVMAFHELGP
                     TIDIHAGGSDLQFPHHENEIAQSEAHNHAPFANYWMHNGFINIDNEKMSKSLGNFILV
                     HDIIKEVDPDVLRFFMISVHYRSPINYNLELVESARSGLERIRNSYQLIEERAQIATN
                     IENQQTYIDQIDAILNRFETVMNDDFNTANAITAWYDLAKLANKYVLENTTSTEVIDK
                     FKAVYQIFSDVLGVPLKSKNADELLDEDVEKLIEERNEARKNKDFARADEIRDMLKSQ
                     NIILEDTPQGVRFKRG"
     gene            17266..17670
                     /locus_tag="RPH49_000767"
     CDS             17266..17670
                     /locus_tag="RPH49_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDY5123953.1"
                     /translation="MDNQQDNHIKLLNPLTLAYMGDAVLDQYVRTYIVLKLKSKPNKL
                     HQMSKKYVSAKSQAQTLEYLMEQEWFTDEEMDILKRGRNAKSHTKAKNTDVQTYRKSS
                     AIEAVIGFLYLEKREERLEALLNKIITIVNER"
     gene            17678..18424
                     /gene="rlmB"
                     /locus_tag="RPH49_000768"
     CDS             17678..18424
                     /gene="rlmB"
                     /locus_tag="RPH49_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDY5123954.1"
                     /translation="MEDTVIVGRHAVREAIITGHPINKILIQEGIKKQQINEILKNAK
                     DQKIIVQTVPKSKLDFLANAPHQGVAALIAPYEYADFDQFLKQQKEKEGLSTVLILDG
                     LEDPHNLGSILRTADATGVDGVIIPKRRSVTLTQTVAKASTGAIEHVPVIRVTNLAKT
                     IDELKDNGFWVAGTEANNATDYRNLEADMSLAIVIGSEGQGMSRLVSDKCDFYIKIPM
                     VGHVNSLNASVAASLMMYEVFRKRHDVGEI"
     gene            18424..18948
                     /locus_tag="RPH49_000769"
     CDS             18424..18948
                     /locus_tag="RPH49_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDY5123955.1"
                     /translation="MKERYLIIDGYNMIGQSPTLSAIAKENLEEARIQLIDAIANYNA
                     VISDEIICVFDAYDQSGVEREYMYHGVKTIFTKEKETADSFIERYVYELYDKHTKHIT
                     VVTSDMSEQHAIFGSGAYRISSREMWRDLKENEIDVSKSLDDISENKPRTRIPLSSEI
                     LAEFEKIRRGHHKK"
     gene            19029..19598
                     /locus_tag="RPH49_000770"
     CDS             19029..19598
                     /locus_tag="RPH49_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDY5123956.1"
                     /translation="MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFN
                     HYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQCLITSVKYDYLRKYLATNKRMDN
                     LINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
                     AQLMHVKEKVIYNAIQRCKNKIKRYFKMI"
     gene            19713..19856
                     /gene="rpmG"
                     /locus_tag="RPH49_000771"
     CDS             19713..19856
                     /gene="rpmG"
                     /locus_tag="RPH49_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002451211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDY5123957.1"
                     /translation="MRKIPLNCEACGNRNYNVPKQEGSATRLTLKKYCPKCNAHTIHK
                     ESK"
     gene            19912..20094
                     /gene="secE"
                     /locus_tag="RPH49_000772"
     CDS             19912..20094
                     /gene="secE"
                     /locus_tag="RPH49_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499089.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDY5123958.1"
                     /translation="MAKKESFFKGVKSEMEKTSWPTKEELFKYTVIVVSTVIFFLVFF
                     YALDLGITALKNLLFG"
     gene            20107..20655
                     /gene="nusG"
                     /locus_tag="RPH49_000773"
     CDS             20107..20655
                     /gene="nusG"
                     /locus_tag="RPH49_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDY5123959.1"
                     /translation="MSEEVGAKRWYAVHTYSGYENKVKKNLEKRVESMNMTEQIFRVV
                     IPEEEETQVKDGKAKTTVKKTFPGYVLVELIMTDESWYVVRNTPGVTGFVGSAGAGSK
                     PNPLLPEEVRFILKQMGLKEKTIDVELEVGEQVRIKSGPFANQVGEVQEIETDKFKLT
                     VLVDMFGRETPVEVEFDQIEKL"
     gene            20836..21258
                     /gene="rplK"
                     /locus_tag="RPH49_000774"
     CDS             20836..21258
                     /gene="rplK"
                     /locus_tag="RPH49_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012664221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDY5123960.1"
                     /translation="MAKKVDKVVKLQIPAGKANPAPPVGPALGQAGVNIMGFCKEFNA
                     RTQDQAGLIIPVEISVYEDRSFTFITKTPPAPVLLKKAAGIEKGSGEPNKTKVGTVTK
                     DQVREIANSKMQDLNAADEEAAMRIIEGTARSMGIVVE"
     gene            21466..22158
                     /gene="rplA"
                     /locus_tag="RPH49_000775"
     CDS             21466..22158
                     /gene="rplA"
                     /locus_tag="RPH49_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDY5123961.1"
                     /translation="MAKKGKKYQEAASKVDRTQHYSVEEAIKLAKETSIANFDASVEV
                     AFRLGIDTRKNDQQIRGAVVLPNGTGKSQSVLVFAKGDKIAEAEAAGADYVGEAEYVQ
                     KIQQGWFDFDVVVATPDMMGEVGKLGRVLGPKGLMPNPKTGTVTMDVKKAVEEIKAGK
                     VEYRAEKAGIVHASIGKVSFTDEQLIENFNTLQDVLAKAKPSSAKGTYFKSVAVTTTM
                     GPGVKIDTASFK"
     misc_feature    22246..22392
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            22430..22930
                     /locus_tag="RPH49_000776"
     CDS             22430..22930
                     /locus_tag="RPH49_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDY5123962.1"
                     /translation="MSAIIEAKKQLVDEIAEVLSNSVSTVIVDYRGLTVAEVTDLRSQ
                     LREAGVEYKVYKNTMVRRAAEKAGIEGLDEFLTGPTAIATSSEDAVAAAKVISGFAKD
                     HEALEIKSGVMEGNVITAEEVKTVGSLPSHDGLVSMLLSVLQAPVRNFAYAVKAIGEQ
                     KEESAE"
     gene            22973..23341
                     /gene="rplL"
                     /locus_tag="RPH49_000777"
     CDS             22973..23341
                     /gene="rplL"
                     /locus_tag="RPH49_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDY5123963.1"
                     /translation="MANHEQIIEAIKEMSVLELNDLVKAIEEEFGVTAAAPVAVAGAA
                     GGADAAAEKTEFDVELTSAGSSKIKVVKAVKEATGLGLKDAKELVDGAPKVIKEALPK
                     EEAEKLKEQLEEVGATVELK"
     gene            23516..24124
                     /locus_tag="RPH49_000778"
     CDS             23516..24124
                     /locus_tag="RPH49_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5123964.1"
                     /translation="MSHYYDEDPSVISNEQRIQYQLNHHKIDLITDNGVFSKDKVDYG
                     SDVLVQTFLKAHPPGPSKRIADVGCGYGPIGLMIAKVSPHHSITMLDVNHRALALVEK
                     NKKINGIDNAIVKESDALSAVEDKSFDFILTNPPIRAGKETVHRIFEQALHRLDSNGE
                     LFVVIQKKQGMPSAKKRMNELFGNVEVVNKDKGYYILRSIKA"
     gene            24339..27890
                     /gene="rpoB"
                     /locus_tag="RPH49_000779"
     CDS             24339..27890
                     /gene="rpoB"
                     /locus_tag="RPH49_000779"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDY5123965.1"
                     /translation="MAGQVVQYGRHRKRRNYARISEVLELPNLIEIQTKSYEWFLREG
                     LIEMFRDISPIEDFTGNLSLEFVDYRLGEPKYDLEESKNRDATYAAPLRVKVRLIIKE
                     TGEVKEQEVFMGDFPLMTDTGTFVINGAERVIVSQLVRSPSVYFNEKIDKNGRENYDA
                     TIIPNRGAWLEYETDAKDVVYVRIDRTRKLPLTVLLRALGFSSDQEIVDLLGDNEYLR
                     NTLEKDGTENTEQALLEIYERLRPGEPPTVENAKSLLYSRFFDPKRYDLASVGRYKTN
                     KKLHLKHRLFNQKLAEPIVNTETGEIVVEEGTVLDRRKIDEIMDVLESNANSEVFELH
                     GSVIDEPVEIQSIKVYVPNDDEGRTTTVIGNAFPDSEVKCITPADIIASMSYFFNLLS
                     GIGYTDDIDHLGNRRLRSVGELLQNQFRIGLSRMERVVRERMSIQDTESITPQQLINI
                     RPVIASIKEFFGSSQLSQFMDQANPLAELTHKRRLSALGPGGLTRERAQMEVRDVHYS
                     HYGRMCPIETPEGPNIGLINSLSSYARVNEFGFIETPYRKVDLDTHAITDQIDYLTAD
                     EEDSYVVAQANSKLDENGRFMDDEVVCRFRGNNTVMAKEKMDYMDVSPKQVVSAATAC
                     IPFLENDDSNRALMGANMQRQAVPLMNPEAPFVGTGMEHVAARDSGAAITAKHRGRVE
                     HVESNEILVRRLVEENGVEHEGELDRYPLAKFKRSNSGTCYNQRPIVAVGDVVEYNEI
                     LADGPSMELGEMALGRNVVVGFMTWDGYNYEDAVIMSERLVKDDVYTSIHIEEYESEA
                     RDTKLGPEEITRDIPNVSESALKNLDDRGIVYIGAEVKDGDILVGKVTPKGVTELTAE
                     ERLLHAIFGEKAREVRDTSLRVPHGAGGIVLDVKVFNREEGDDTLSPGVNQLVRVYIV
                     QKRKIHVGDKMCGRHGNKGVISKIVPEEDMPYLPDGRPIDIMLNPLGVPSRMNIGQVL
                     ELHLGMAAKNLGIHVASPVFDGANDDDVWSTIEEAGMARDGKTVLYDGRTGEPFDNRI
                     SVGVMYMLKLAHMVDDKLHARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGA
                     AYTLQEILTYKSDDTVGRVKTYEAIVKGENISRPSVPESFRVLMKELQSLGLDVKVMD
                     EQDNEIEMTDVDDDDVVERKVDLQQNDAPETQKEVTD"
     gene            28054..31650
                     /gene="rpoC"
                     /locus_tag="RPH49_000780"
     CDS             28054..31650
                     /gene="rpoC"
                     /locus_tag="RPH49_000780"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDY5123966.1"
                     /translation="MKIGLASPEKIRSWSFGEVKKPETINYRTLKPEKDGLFCERIFG
                     PTKDWECSCGKYKRVRYKGMVCDRCGVEVTKSKVRRERMGHIELAAPVSHIWYFKGIP
                     SRMGLLLDMSPRALEEVIYFASYVVVDPGPTGLEKKTLLSEAEFRDYYDKYPGQFVAK
                     MGAEGIKDLLEEIDLDEELKLLRDELESATGQRLTRAIKRLEVVESFRNSGNKPSWMI
                     LDVLPIIPPEIRPMVQLDGGRFATSDLNDLYRRVINRNNRLKRLLDLGAPGIIVQNEK
                     RMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSGRSV
                     IAVGPSLKMYQCGLPKEMALELFKPFVMKELVQREIATNIKNAKSKIERMDDEVWDVL
                     EEVIREHPVLLNRAPTLHRLGIQAFEPTLVEGRAIRLHPLVTTAYNADFDGDQMAVHV
                     PLSKEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYYLTLERKDAVNTGAIFN
                     NTNEVLKAYANGFVHLHTRIGVHASSFNNPTFTEEQNKKILATSVGKIIFNEIIPDSF
                     AYINEPTQENLERKTPNRYFIDPTTLGEGGLKEYFENEELIEPFNKKFLGNIIAEVFN
                     RFSITDTSMMLDRMKDLGFKFSSKAGITVGVADIVVLPDKQQILDEHEKLVDRITKQF
                     NRGLITEEERYNAVVEIWTDAKDQIQGELMQSLDKTNPIFMMSDSGARGNASNFTQLA
                     GMRGLMAAPSGKIIELPITSSFREGLTVLEYFISTHGARKGLADTALKTADSGYLTRR
                     LVDVAQDVIVREEDCGTDRGLLVSDIKEGTEMIEPFIERIEGRYSKETIRHPETDEII
                     IRPDELITPEIAKKITDAGIEQMYIRSAFTCNARHGVCEKCYGKNLATGEKVEVGEAV
                     GTIAAQSIGEPGTQLTMRTFHTGGVAGSDITQGLPRIQEIFEARNPKGQAVITEIEGV
                     VEDIKLAKDRQQEIVVKGANETRSYLASGTSRIIVEIGQPVQRGEVLTEGSIEPKNYL
                     SVAGLNATESYLLKEVQKVYRMQGVEIDDKHVEVMVRQMLRKVRIIEAGDTKLLPGSL
                     VDIHNFTDANREAFKHRKRPATAKPVLLGITKASLETESFLSAASFQETTRVLTDAAI
                     KGKRDDLLGLKENVIIGKLIPAGTGMRRYSDVKYEKTAKPVAEVESQTEVTE"
     gene            31787..32041
                     /locus_tag="RPH49_000781"
     CDS             31787..32041
                     /locus_tag="RPH49_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal L7Ae/L30e/S12e/Gadd45 family protein"
                     /protein_id="HDY5123967.1"
                     /translation="MSKEKVARFNKQHFVVGLKETLKALKKDQVTSLIIAEDVEVYLM
                     TRVLSQINQKNIPVSFFKSKHALGKHVGINVNATIVALIK"
     gene            32139..32552
                     /gene="rpsL"
                     /locus_tag="RPH49_000782"
     CDS             32139..32552
                     /gene="rpsL"
                     /locus_tag="RPH49_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDY5123968.1"
                     /translation="MPTINQLVRKPRQSKIKKSDSPALNKGFNSKKKKFTDLNSPQKR
                     GVCTRVGTMTPKKPNSALRKYARVRLSNNIEINAYIPGIGHNLQEHSVVLVRGGRVKD
                     LPGVRYHIVRGALDTSGVDGRRQGRSLYGTKKPKN"
     gene            32618..33088
                     /gene="rpsG"
                     /locus_tag="RPH49_000783"
     CDS             32618..33088
                     /gene="rpsG"
                     /locus_tag="RPH49_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013054923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDY5123969.1"
                     /translation="MPRKGSVPKRDVLPDPIHNSKLVTKLINKIMLDGKRGTAQRILY
                     SAFDLVEQRSGRDALEVFEEAINNIMPVLEVKARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVNYARLRGEKTMEDRLANEILDAANNTGGAVKKREDTHKMAEANKAFAHYRW"
     gene            33211..35292
                     /gene="fusA"
                     /locus_tag="RPH49_000784"
     CDS             33211..35292
                     /gene="fusA"
                     /locus_tag="RPH49_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDY5123970.1"
                     /translation="MAREFSLEKTRNIGIMAHIDAGKTTTTERILYYTGRIHKIGETH
                     EGASQMDWMEQEQDRGITITSAATTAAWEGHRVNIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFVNKMDKLGANFEYSVSTLHDRLQANAA
                     PIQLPIGAEDEFEAIIDLVEMKCFKYTNDLGTEIEEIEIPEDHLDRAEEARASLIEAV
                     AETSDELMEKYLGDEEISVSELKEAIRQATTNVEFYPVLCGTAFKNKGVQLMLDAVID
                     YLPSPLDVKPIIGHRASNPEEEVIAKADDSAEFAALAFKVMTDPYVGKLTFFRVYSGT
                     MTSGSYVKNSTKGKRERVGRLLQMHANSRQEIDTVYSGDIAAAVGLKDTGTGDTLCGE
                     KNDIILESMEFPEPVIHLSVEPKSKADQDKMTQALVKLQEEDPTFHAHTDEETGQVII
                     GGMGELHLDILVDRMKKEFNVECNVGAPMVSYRETFKSSAQVQGKFSRQSGGRGQYGD
                     VHIEFTPNETGAGFEFENAIVGGVVPREYIPSVEAGLKDAMENGVLAGYPLIDVKAKL
                     YDGSYHDVDSSEMAFKIAASLALKEAAKKCDPVILEPMMKVTIEMPEEYMGDIMGDVT
                     SRRGRVDGMEPRGNAQVVNAYVPLSEMFGYATSLRSNTQGRGTYTMYFDHYAEVPKSI
                     AEDIIKKNKGE"
     gene            35509..36693
                     /gene="tuf"
                     /locus_tag="RPH49_000785"
     CDS             35509..36693
                     /gene="tuf"
                     /locus_tag="RPH49_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDY5123971.1"
                     /translation="MAKEKFDRSKEHANIGTIGHVDHGKTTLTAAIATVLAKNGDSVA
                     QSYDMIDNAPEEKERGITINTSHIEYQTDKRHYAHVDCPGHADYVKNMITGAAQMDGG
                     ILVVSAADGPMPQTREHILLSRNVGVPALVVFLNKVDMVDDEELLELVEMEVRDLLSE
                     YDFPGDDVPVIAGSALKALEGDAQYEEKILELMEAVDTYIPTPERDSDKPFMMPVEDV
                     FSITGRGTVATGRVERGQIKVGEEVEIIGLHDTSKTTVTGVEMFRKLLDYAEAGDNIG
                     ALLRGVAREDVQRGQVLAAPGSITPHTEFKAEVYVLSKDEGGRHTPFFSNYRPQFYFR
                     TTDVTGVVHLPEGTEMVMPGDNVEMTVELIAPIAIEDGTRFSIREGGRTVGSGVVTEI
                     IK"
     gene            complement(36975..38150)
                     /locus_tag="RPH49_000786"
     CDS             complement(36975..38150)
                     /locus_tag="RPH49_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDY5123972.1"
                     /translation="MLDWFQLANNKENKTIQLRRYLHQYPELSFEEFQTHDYIVNQLS
                     QLSCDIETPIGRNGIKATFKGLGTGPTIALRADFDALPVEELNDVPYKSKNPGCMHAC
                     GHDGHTAILLTVAEILDEHKHLLEGNVVLIFQYGEEIMPGGSQEMIDAGCLENVDRIY
                     GTHLWSGYPTGTIHSRAGAIMASPDEFSVTIKGRGGHGAKPHETIDPIVIMAEFILSA
                     QKIISRTIDPVKQAVLSFGMIQAGTTDSVIPDQAFCKGTVRTFDSDIQNHVMDKMDKL
                     LQGLAIANDINYDLNYIKGYLPVHNNEKAYQVIKEATNDLHVRFNESDLMMIGEDFSH
                     YLKVRPGAFFLTGCGNESKGITAPHHNPKFDIDEKSLKYAVAVFLKIIELEQVFKTN"
     gene            38321..39508
                     /locus_tag="RPH49_000787"
     CDS             38321..39508
                     /locus_tag="RPH49_000787"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDY5123973.1"
                     /translation="MVQSLHEFLEENINYLKENGLYNEIDTIEGANGPEIKINGKSYI
                     NLSSNNYLGLATNEDLKSAAKAAIDTHGVGAGAVRTINGTLDLHDELEETLAKFKGTE
                     AAIAYQSGFNCNMAAISAVMNKNDAILSDELNHASIIDGCRLSKAKIIRVNHSDMDDL
                     RAKAKEAVESGQYNKVMYITDGVFSMDGDVAKLPEIVEIAEEFGLLTYVDDAHGSGVM
                     GKGAGTVKHFGLQDKIDFQIGTLSKAIGVVGGYVAGTKELIDWLKAQSRPFLFSTSLA
                     PGDTKAITEAVKKLMDSTELHDKLWDNAQYLKNGLSKLGYDTGESETPITPVIIGDEK
                     TTQEFSKRLKDEGVYVKSIVFPTVPRGTGRVRNMPTAAHTKDMLDEAIAAYEKVGKEM
                     KLI"
     gene            39775..40653
                     /gene="hchA"
                     /locus_tag="RPH49_000788"
     CDS             39775..40653
                     /gene="hchA"
                     /locus_tag="RPH49_000788"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HDY5123974.1"
                     /translation="MSQDVNELSKQPTPDKAEDNAFFPSPYSLSQYTATKTDFDGVEH
                     KGAYKDGKWKVLMIAAEERYVLLENGKMFSTGNHPVEMLLPLHHLMEAGFDVDVATLS
                     GYPVKLELWAMPTEDEAVISTYNKLKEKLKQPKKLADVIKNELGPDSDYLSVFIPGGH
                     AAVVGISESEDVQQTLDWALDNDRFIVTLCHGPAALLSAGLNREKSPLEGYSVCVFPD
                     SLDEGANIEIGYLPGRLKWLVADLLTKQGLKVVNDDMTGRTLKDRKLLTGDSPLASNE
                     LGKLAVNEMLNAIQNK"
     gene            40812..42449
                     /locus_tag="RPH49_000789"
     CDS             40812..42449
                     /locus_tag="RPH49_000789"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDY5123975.1"
                     /translation="MSYSIGIDYGTASGRVFLINTTNGQVVSKFVKPYTHGVIESELN
                     GLKIPYTYALQNSNDYLEIMEEGISYIVRESKIDPVNIVGIGIDFTSSTIIFTDENLN
                     PVHNLKQFKNNPHAYVKLWKHHGAYKEAEKLYQTAIENNNKWLGHYGYNVSSEWMIPK
                     IMEVMNRAPEIMEKTAYIMEAGDWIVNKLTNKNVRSNCGLGFKAFWEEETGFHYDLFD
                     KIDPKLSKVIQDKVSAPVVNIGEVVGKLDDKMAQKLGLSKETMVSPFIIDAHASLLGI
                     GSEKDKEMTMVMGTSTCHLMLNEKQHQVPGISGSVKGAIIPELFAYEAGQSAVGDLFE
                     YVAKQAPKSYVDEAANRNMTVFELMNEKIKHQMPGESGLIALDWHNGNRSVLSDSNLT
                     GCIFGLTLQTKHEDIYRAYLEATAFGTKMIMQQYQDWHMEVEKVFACGGIPKKNAVMM
                     DIYANVLNKKLIVMDSEYAPAIGAAILGAVSGGAHNSINDAVDAMKEPILYEINPEAE
                     KVQRYETLFKAYKALHDIHGYKKANIMKDIQSLRVEG"
     gene            42663..43628
                     /locus_tag="RPH49_000790"
     CDS             42663..43628
                     /locus_tag="RPH49_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDY5123976.1"
                     /translation="MKKIMITGALGQIGTELVVKCREIYGTDNVLATDIREPEADSPV
                     QNGPFEILDVTDRDRMFELVRDFEADSLMHMAALLSATAEKNPILAWDLNMGGLMNAL
                     EAARTYNLHFFTPSSIGAFGDSTPKVNTPQVTIQQPTTMYGVNKVAGELLCQYYFKRF
                     GVDTRSVRFPGLISHVKEPGGGTTDYAVEIYFKAVREGHYTSFIDKGTYMDMMYMDDA
                     IEAIIKLMEADDAKLETRNGYNLSAMSFDPEMVKEAIQEYYPNFTLDYDVDPIRQGIA
                     NSWPDSIDTSCSRGEWGFDPKYDLASMTKLMLEAIEQKDTVKNNN"
     gene            43963..45039
                     /locus_tag="RPH49_000791"
     CDS             43963..45039
                     /locus_tag="RPH49_000791"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDY5123977.1"
                     /translation="MSQAVKVERRETLKQKPNTSQLGFGKYFTDYMLSYDYDAEKGWH
                     DLKIVPYGPIEISPAAQGVHYGQSVFEGLKAYKKDGEVALFRPEENFKRLNNSLARLE
                     MPQVDEAELLEGLKQLVDIERDWIPEGEGQSLYIRPFVFATEGALGVGASHQYKLLII
                     LSPSGAYYGGETLKPTKIYVEDEYVRAVRGGVGFAKVAGNYAASLLAQTNANKLGYDQ
                     VLWLDGVEQKYIEEVGSMNIFFVENGKVITPELNGSILPGITRKSIIELAKNLGYEVE
                     ERRVSIDELFESYDKGELTEVFGSGTAAVISPVGTLRYEDREIVINNNETGEITQKLY
                     DVYTGIQNGTLEDKNGWRVVVPKY"
     gene            45289..45972
                     /locus_tag="RPH49_000792"
     CDS             45289..45972
                     /locus_tag="RPH49_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5123978.1"
                     /translation="MEWILFDKDGTLIEFDRSWEKIGVRFVQSLLETFPVHNKEAALR
                     QLGVIKESIDPKSVMGSGSLQQIIQAFNDVTGQDTTDWSKSTSQKLVDERIPEINWVE
                     GVKEALIDLKAKGYQLGIVTSDTKKGVEQFLAHTNAISLFDLIISTEADAYEKPNPKV
                     LSPLFEQYNVDPQKVAIVGDTANDMKTASNANLGMAIGVLTGIATKEELHEADIILNS
                     AADILEALN"
     gene            complement(46088..46750)
                     /locus_tag="RPH49_000793"
     CDS             complement(46088..46750)
                     /locus_tag="RPH49_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDY5123979.1"
                     /translation="MNNYGIPQNAIITIAGTVGVGKSTLTQALADKLNFKTSFENVEH
                     NPYLDKFYSDFERWSFHLQIYFLAERFKEQKRMFEYGGGFVQDRSIYEDVDIFAKMHE
                     EEGTMSKEDFKTYSDLFNAMVMTPYFPKPDVMIYLECNYDEVIDRIIERGREMEINTD
                     PEYWKKLFKRYDDWINSFNACPVVRININEYDIHKDPESLNPMIDKIARIIQTYRQVD
                     TR"
     gene            complement(46743..47360)
                     /locus_tag="RPH49_000794"
     CDS             complement(46743..47360)
                     /locus_tag="RPH49_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDY5123980.1"
                     /translation="MNKPFIAIEGPIGVGKSSLAHKLSQTLDFYEEKEIITENPFLSD
                     FYEDISKWSFQTEMFFLCNRYKQFQDVTQLNQGVVSDYHIHKNKIFAKNTLSSVEFQK
                     FSKIYDILTEDMIMPNMIIFLDADLDVLKSRIAKRNRSFEHQIEDEYLLKLKKDYREY
                     YESLQSNGSNVVLIDTTSIDFLKNEQDYEDILHIILPMIGDITNE"
     gene            47427..47897
                     /locus_tag="RPH49_000795"
     CDS             47427..47897
                     /locus_tag="RPH49_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HDY5123981.1"
                     /translation="MTNDIYFMTLAIEEAKKAAQLGEVPIGAIITKDDEVIARAHNLR
                     ETLQQPTAHAEHIAIERAAKVLGSWRLEGCTLYVTLEPCVMCAGTIVMSRIPRVVYGA
                     DDPKGGCSGSLMNLLQQSNFNHRAIVDKGVLKEACSTLLTTFFKNLRANKKSTN"
     gene            48044..48913
                     /locus_tag="RPH49_000796"
     CDS             48044..48913
                     /locus_tag="RPH49_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDY5123982.1"
                     /translation="MIKLIATDMDGTLLNAAHEISQPNIDAIKYAQEQGITVVIATGR
                     AFYEAQAPVADTDLTVPYICLNGAEVRDETFNVMSTSHLNKSLVHKITNVLKDAGIYY
                     QVYTSRAIYTEDPQRDLDIYIDIAERAGQHANVERIKNGIQRRIDNGTLKVVDNYDAI
                     ENIPGELIMKILAFDGNLEKIDKASKILAESPNLAISSSSRGNIEITHSDAQKGIALE
                     TIAERLGIEMKDVMAIGDNLNDLSMLEKVGYPVAMENGAEEVKKIAKYVTDTNENSGV
                     GKAIMKLLREQQV"
     gene            48934..49500
                     /locus_tag="RPH49_000797"
     CDS             48934..49500
                     /locus_tag="RPH49_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDY5123983.1"
                     /translation="MKGLIIIGSAQVNSHTSALARYLTEHFKTHDIEAEIFDLAEKPL
                     NQLDFSGTTPSIDEIKQNMKDLKEKAMAADFLILGTPNYHGSYSGILKNALDHLNMDY
                     FKMKPVGLIGNSGGIVSSEPLSHLRVIVRSLLGIAVPTQIATHDSDFAKNEDGSYYLN
                     DSEFQLRARLFVDQIVSFVNNSPYEHLK"
BASE COUNT        17837 a         7232 c         9557 g        15042 t
ORIGIN      
        1 tatgtctggt gactatagca aggaggtcac acctgttccc atgccgaaca cagaagttaa
       61 gctccttagc gtcgatggta gtcgaactta cgttccgcta gagtagaacg ttgccaggca
      121 aaaatggatg cgatgagccg cattgagacc gtaaggtctc tttttttatg tctaaaacgt
      181 caaaataaaa gttaacacaa agaaaaatgg cttggcgaag tgaaaacgtt tgaatctgac
      241 gaaacgagaa aagagcgcaa cgagtttagt agagctaaat gagtaagcga gagccgaaga
      301 agaggaaaga agcaagcgat tgtcacaagt caagaaaggt tcttagcgag gatggtagcc
      361 aacttacgtt ccgctagagt agaacgttgc caggcaaaaa atggatgcga tgagccgcat
      421 tgaaatgctc ccttcaaagt agacatagat gtactgctat atatgtttca agaatatgaa
      481 aaaagcgtgt cgtttcaata cctaatcgat acattacaat tagatattaa tgtcaatact
      541 ttgtatccta agtataaata ttataaaacc catggtggaa atgataattt aataatgtgc
      601 acttttgatt gtctaagtat gtacaacttt aattttgtgt ttatataaat ttaaaatgat
      661 atcatcgaaa acaaaatatt gtataaatag agaagagcag taagacggta tctaattgaa
      721 aatgatctta ctgctctttt atatacttta ttgaaataca aaaaggaaat taattattat
      781 acaatagaca agctattgca taagtaacac taacttttat caaagaagtg ttactttata
      841 attaatgttt ttattagagc gtctacatgc ggttttaaag catcatcgtc tataccgcca
      901 aagcctaata taaatttagg ggttttctta tagtcttggt catcatcaaa attataaact
      961 tgtaatttta actttacttt atttgctcta tcaagacact cttgtaatgt taatccattt
     1021 tttactgtaa ttgtaaaatg catacctgtt tcagcacctt gaatatcaag ttgctctttg
     1081 tatggcttca atctttttaa aatataggtt agttttctac gataaattcg tctcatttta
     1141 tttaaatgcc tttcaaaacc accggaagat ataaacgttg caataaggtt ttgcatatga
     1201 acaggtacag tgttgccttc aatgtgattt tgagaatgat attttttcat tatagaatag
     1261 ggtaacacca tatatgcaac acgacagcta ggaaaaatag actttgaaaa tgtactgata
     1321 taaatcactt tttctcctct tgaatataga ccttgtattg ctggaatggg tttaccgaaa
     1381 tatctaaact cagaatcata atcatcttct ataataaatc gttcttcttt ttcttgagcc
     1441 cattgtatta attgagttcg cttttttaag tccatcacat atccagttgg aaattgatgg
     1501 gaaggcgtta tatatactat atttttttgt gatttaataa cttcatctac gtttattcca
     1561 ttatcttcaa cttcaatttg ttcatattca acttgttttt tatctaaaat atttttgatt
     1621 ggtggataac taggtttttc gataataaac gttgaagtat aaagtaaatc gactaattga
     1681 tttactaatt gttcggtaga tgagccaatt ataatttgat taggatcaca aattacacca
     1741 cgattagtaa ataaataaaa tgccagttga aatcttaaat gtaattctcc ttgaaaatgt
     1801 cctctacgta attggttcaa atgatttgta tcataaagat ctttggaata ctttctgaaa
     1861 agttctatag ggaaatgttt cgtatctatt tcatccaaat taaaagcata atcataagct
     1921 tcatcactcg cttttggttt atatgaatca tcatcaaaaa gagaggggat aggttgattg
     1981 tttaaaattg ttaaagattc aatttcggac acaaaatatc cagagcgagg tcttgaataa
     2041 atgtaacctt catctaatag aagttgatat gcatgttcta cggttgtttg gctgatagat
     2101 aaatgtttgc ttaattgtct tttagaataa aatttatcac cttctttaaa ttgaccttca
     2161 attatttgtt tttttaattt ttcataaagt tgatggtata aagtgttttt caattttata
     2221 actgacctcc taaatttgtc ttattttgta cctttttaaa tatcagttta tacattacaa
     2281 tgtatttaat caacttgaaa aggggtttta tgtataatga gtaaaattat tggatcagac
     2341 agagtcaaaa gaggtatggc tgaaatgcaa aaaggcggcg ttattatgga tgtcgttaat
     2401 gctgagcaag caagaattgc agaagaagct ggcgcggtag cagttatggc attagaacga
     2461 gtaccttctg atattagagc tgctggtggc gttgcacgta tggcaaaccc taaaattgta
     2521 gaagaagtaa tgaatgctgt ttctattcca gtcatggcta aagcacgtat tggtcatatc
     2581 actgaagcaa gagtattaga ggcgatgggt gttgactata ttgatgaatc agaagtgtta
     2641 acaccagcag atgaggaata tcacttaaga aaagatcaat ttacagtacc atttgtatgt
     2701 ggatgtcgta atttaggtga agctgcgcgt agaattggtg aaggtgctgc tatgttacgt
     2761 actaaaggtg aaccaggtac aggtaatatt gttgaagctg taagacatat gagacaagtt
     2821 aattcagaag ttagtcgatt gactgtaatg aatgatgatg agattatgac tttcgcgaaa
     2881 gatatcggtg cgccttatga aattttaaaa caaattaaag acaatggtcg tttaccggta
     2941 gttaactttg cagctggtgg cgttgcgact cctcaagatg ctgctttaat gatggaatta
     3001 ggtgccgatg gtgtattcgt tggatcaggt atttttaaat cagaagatcc agaaaaattt
     3061 gctaaagcaa ttgttcaagc aacaacacat taccaagact atgaactaat tggaagatta
     3121 gcaagtgaac ttggcactgc tatgaaaggt ttagatatca atcaattatc attagaagaa
     3181 cgtatgcaag agcgtggttg gtaagatatg aaaataggtg tattagcatt acaaggtgca
     3241 gtacgtgaac atattagaca tattgaatta agtggtcatg aaggtattgc agttaaaaaa
     3301 gttgaacaat tagaagaaat cgagggctta atattacctg gtggcgagtc tacaacgtta
     3361 cgtcgattaa tgaatttata tggatttaaa gaggctttac aaaattcaac tttacctatg
     3421 tttggtacat gcgcaggatt aatagttcta gcgcaagata tagttggtga agaaggatac
     3481 cttaacaagt tgaatattac tgtacaacga aactcattcg gtagacaagt tgacagcttt
     3541 gaaacagaat tagatattaa aggtatcgct acagatattg aaggtgtctt tataagagcc
     3601 ccacacattg aaaaagtagg tcaaggcgta aatatcctat gtaaggttaa tgagaaaatt
     3661 gtagctgtcc agcaaggtaa atatttaggc gtatcattcc atcctgaatt aacagatgac
     3721 tatagagtaa ctgattactt tattaatcat attgtaaaaa aagcatagct taatgtatgc
     3781 taaatcaacg aattattgat atttatagat ttgttgagaa gacaatatct ccttcaaact
     3841 tagctttgga ggagttgttt tttatgtcaa aattaaaaat gataaaaaat aaagatatac
     3901 ataagaaaaa accccttcaa agacactgag aatagtcaaa attttgaagg ggttaattcg
     3961 atgttgatgt atttgttaaa taaagaatcc agcgattgca gctgaaatga aagatactag
     4021 tgttgcaccg aataataatt tcaaaccaaa gcgggcaact gtatctcctt ttttgtcatt
     4081 aagagattta atcgcacctg aaataatacc aatagagcta aaattagcaa atgatactaa
     4141 gaatacagat gtaacacctt ttgcgtgttc agataaatca ctaagtttac cgagtgcttg
     4201 cattgctaca aattcgttag ataatagttt tgtcgccata actgaaccgg cttgaactgc
     4261 atcttgccat ggcacaccga ctaagaatgc aaatggtgca aagacaaaac caattaatgt
     4321 ttggaaatcc caagaaatag cgccacctga aactgtacta aagatattgc ttacaattcc
     4381 atttaataga gcgataatag caatgtatcc gattaacatt gcgcctacaa tgacagctac
     4441 tttaaatcca tctaaaatat attctcctag catttcgaag aatgattgtt gtctttcttc
     4501 agtttcttca actaataatt tgtcatcttc ttcattaact ttataagggt taataattga
     4561 agcgatgatg aaaccaccaa ataagtttaa gacaacagcc gttacaacat atttaggttc
     4621 aattaaggta aagtatgcac cgataattga agcagaaaca gtcgacattg ctgaagctgt
     4681 taatgtgtat aaacgttgct taggtatgta tggtaattgt tttttaattg aaataaatac
     4741 ttcagattgt cccaaaattg ctgcagcaac tgcattgtat gattctaaac gtcccatacc
     4801 attaatttta gaaattaaga atcctaaaac attaatgatt aaaggtaaaa tctttgtgta
     4861 ttgaaggata ccgataatcg ctgaaataaa tacgataggt aataatacac tgaagaagaa
     4921 tggtggttgc ttaggatcga tatattgaat accaccgaat acaaagttaa caccatctgc
     4981 tgcttttaat aataagtagt taaaaccgtt tgaaatacca ccaataacct tgattcccat
     5041 tgtagtttta agcaagataa atgcaaagat aagctgaatt gcaagtaaaa ttcctacata
     5101 tttccagcga atatttttcc tgtctgagct aaatagaaac gcaagtgcta aaaagaagat
     5161 aattccgata atcccaatta gaatatgcat atatttctca ttcctttagt tttttctaca
     5221 atctatcata caataaaatg gaagggctaa catcataaat ttttgaaaat ataaaaacaa
     5281 attaattgaa aaaggtcaaa ataggtcata taatatagtc aaagaaggtc aaaaaggggt
     5341 gatatacatg cacaatatgt ctgacatcat agaacaatac atcaaacgtt tatttgaaga
     5401 gtcgaatgaa gatgtcgttg aaattcagag agcgaatatc gcacagcgct ttgattgtgt
     5461 accatcacaa ttaaattatg taatcaaaac acgattcact aatgaacatg gttatgaaat
     5521 cgaaagtaaa cgtggtggtg gtggttacat ccgaatcact aaaattgaaa ataaagatgc
     5581 aacaggttat attaatcatt tgcttcagct gattggacct tctatttctc aacaacaagc
     5641 ttattatatt attgatgggc ttttagataa aatgttaata aatgaacgtg aagctaaaat
     5701 gattcaagca gttattgata gagaaacgct atcaatggat atggtttcta gagatattat
     5761 tagagcaaat attttaaaac gtttgttacc agttataaat tattactaaa tgaaatgagg
     5821 tgttgaagtg ctttgtgaaa attgtcaact taatgaagcg gaattaaaag ttaaagttac
     5881 aagtaaaaat aaaacagaag aaaaaatggt gtgtcaaact tgtgctgagg ggcaccatcc
     5941 gtggaatcaa gctaatgaac aacctgaata tcaagaacat caagataatt tcgaagaagc
     6001 atttgttgtt aagcaaattt tacaacattt agctacgaaa catggcatta attttcaaga
     6061 agtagcgttt aaagaagaaa aacgttgccc atcatgtcat atgactttga aagatattgc
     6121 acatgttggt aaatttgggt gtgctaattg ttatgcaaca tttaaagatg acatcattga
     6181 tatcgtccgc agagttcaag gtggacaatt tgagcacgtt ggaaagacac cacattcttc
     6241 acataaaaag atagctttaa agcgaaaaat cgaagaaaag aatgaatatt tgaaaaaact
     6301 tattgaaatc caagattttg aggaagcagc cattgttaga gatgaaatta aagcactaaa
     6361 agctgagagt gaggtgcaac atgatgacgc ataatattca tgataatatc agccaatgga
     6421 tgaaaagtaa tgaagaaaca cccattgtta tgtcttctag aattcggtta gcgcgtaatt
     6481 tagaaaatca tgtgcatcca ctaatgtatg ctactgaaaa tgatggattt agagttataa
     6541 atgaggtaca agatgccttg ccaaattttg aattaatgcg tcttgatcaa atggatcaac
     6601 aaagtaaaat gaagatggtt gcaaagcatt tgattagtcc tgaactaata aaacaaccag
     6661 cagccgcagt attagtgaat gatgatgaat ctttaagtgt catgataaat gaagaggacc
     6721 atattcgtat tcaagctatg ggaactgaca cgacattaca ggctttatat aatcaagctt
     6781 catcaattga tgatgaatta gataaaagcc ttgatataag ttatgatgaa caacttggtt
     6841 atttaactac atgtcctacc aatataggta ctggtatgag agcaagcgtg atgctacatt
     6901 taccaggtct atctattatg aaaagaatga cacggattgc tcaaaccatt aatcgttttg
     6961 gatatacaat cagaggtatt tacggtgaag gttcgcaagt ttatggacat acttatcaag
     7021 tatccaacca acttacactt ggtaaatctg agttagaaat catagaaaca ttaacagaag
     7081 ttgttaatca aatcattcat gaagaaaaac aaatacgaca aaagttagac acttataatc
     7141 aattagaaac acaagaccgt gtttttcgct cgctaggtat tttacaaaac tgtagaatga
     7201 taactatgga agaggcttct tatagattaa gcgaagttaa acttggtata gatttaaatt
     7261 acattgaatt acaaaacttt aaatttaatg aattgatggt agctatacag tcaccatttt
     7321 tattagatga agaagatgac aaatctgtaa aagaaaaacg agcagatata ctaagagaac
     7381 atataaagta ggaggtcatt atttatgtta tttggtagat taactgagcg tgcacagcgc
     7441 gtattagcac atgcacaaga agaagcaatt cgtttaaatc attcaaatat aggaacagaa
     7501 cacctattat tgggattaat gaaagaacct gaaggaattg ctgcaaaagt attagaaagt
     7561 tttaatatca ctgaagataa agtaattgaa gaagttgaaa aattaatcgg acatggtcaa
     7621 gatcatgttg gtacattgca ttatacacct agagctaaaa aagtcattga attatcgatg
     7681 gatgaagcta gaaaattaca tcacaatttt gttggaacgg aacatatttt attaggcttg
     7741 attcgtgaaa atgaaggtgt tgcagcaaga gtttttgcaa atctagattt aaatattact
     7801 aaagcacgtg cacaagttgt gaaagcttta ggaaaccctg aaatgagtaa taaaaatgca
     7861 caagctagta agtcaaataa tactccaact ttagatagtt tagctcgtga cttaacagtc
     7921 attgccaaag acggtacatt agatcctgtt ataggacgtg ataaagaaat tacacgtgta
     7981 attgaagtat taagtagacg tacgaaaaac aatcctgtgc ttattggaga gccaggtgtt
     8041 ggtaaaactg ctattgctga aggtttagcg caagccatag tgaataatga ggtaccagag
     8101 acattaaaag ataaacgtgt tatgtcttta gatatgggaa cagtagttgc aggtactaaa
     8161 tatcgtggtg aatttgaaga gcgtctgaaa aaggttatgg aagaaatcca acaagcaggt
     8221 aatgtcatcc tatttattga tgagttgcat actttagttg gtgctggtgg tgctgaaggt
     8281 gctatcgatg cttcgaatat tttgaagccg gcattagcac gtggtgaatt acaatgtatt
     8341 ggtgctacta cattagatga atatcgcaaa aatattgaaa aagacgcggc tttagaacgt
     8401 cgtttccaac ctgtacaagt tgatgaacct tcagtagtag atacagttgc tattttaaaa
     8461 ggattaagag atcgttacga agcacaccat cgtattaata tttcagacga agctattgaa
     8521 gcagctgtta aattaagtaa cagatacgtt tcagatcgtt tcttaccaga taaagcaatt
     8581 gatttaattg atgaagcaag ttctaaagta agacttaaga gtcatacgac acctaataat
     8641 ttaaaagaaa ttgaacaaga aattgaaaaa gttaaaaatg aaaaagatgc cgcagtacat
     8701 gctcaagagt ttgaaaatgc tgctaacctg cgtgataaac aaacaaaact tgaaaagcaa
     8761 tatgaagaag ctaaaaatga atggaagaat gcacaaaatg gcatgtcaac ttcattgtca
     8821 gaagaagata ttgctgaagt tattgcagga tggacaggta tcccattaac taaaatcaat
     8881 gaaacagaat ctgaaaaact tcttagtcta gaagatacat tacatgagag agttattggg
     8941 caaaaagatg ctgttaattc aatcagtaaa gcggttagac gtgcccgtgc agggttaaaa
     9001 gatcctaaac gaccaattgg tagctttatc ttccttggac caactggtgt tggtaaaact
     9061 gaattagcta gagctttagc tgaatcaatg tttggcgatg atgatgcgat gatccgtgta
     9121 gacatgagtg aatttatgga aaaacacgca gtgagccgat tagttggtgc tcctccagga
     9181 tatgttggtc atgatgatgg tggacaatta actgaaaaag ttagacgtaa accgtattct
     9241 gtaattttat ttgatgaaat tgaaaaagca catccagatg tatttaatat tctattacaa
     9301 gttttagatg acggacattt gacagataca aaaggacgta cagttgattt cagaaataca
     9361 attatcataa tgacatcaaa cgttggagca caagaattac aagatcaacg atttgctgga
     9421 ttcggtggtt caagtgatgg acaagattat gaaacaattc gaaaaacgat gttaaaagaa
     9481 ttaaaaaatt cattccgtcc agaattttta aaccgtgtag atgatatcat tgtattccat
     9541 aaactaacaa aagaagaatt aaaagaaatt gtaacaatga tggttaataa attaacaaat
     9601 cgattatctg aacaaaacat aaatattatt gttactgata aagcgaaaga caaaatcgca
     9661 gaagaaggat atgatccaga atatggtgca agaccattaa ttagagcgat acaaaaaact
     9721 atcgaagata atttaagtga attaatatta gatggtaatc aaattgaagg taagaaagtt
     9781 acagtagatc atgatggtaa agagtttaaa tatgacattg ctgaacaaac ttcagaaact
     9841 aaaacaccat cgcaagcata attataaaac agtccaaaac aaattaaagt tttgggctgt
     9901 ttttttagta gcattgaact atagaaattc gtgaaagtat ccatcaacga aacaatctaa
     9961 taaaataatc atcaaaggat agttaagaat tatatgaaac aagttaatga gcctacagcg
    10021 atagcataaa ggtatgaatt tttataaagg ttttttgttt gaagatacta gcaacttacg
    10081 tcaaaataaa ataggtctat ataatattgt gataaatcta gagaaaagag tttactaaga
    10141 aattattaag attttatctt tgaaagatac cgactatcaa catgatgtaa gtttatttta
    10201 taatattcat aaaaaataaa tctgataaaa cagtttgcgt tagtagtcat gttaaaatac
    10261 aaacaaatgt aactcacatt taatttgtca taatgggaat gtgcgtttaa aatagatttg
    10321 ttcaaaggaa agtggaggtg caattttggc caagaaaaaa gtgatttttg aatgtatggc
    10381 ttgtggttat caatctccta aatggatggg gaaatgtcct aattgtggcg cttggaatca
    10441 aatggaggaa attgttgaaa aagcagccaa tcctaaacat ggagtgaaaa ccaaggaatt
    10501 agcaggtaaa gtacaaaaat taaatagtat taaacatgaa acaacgccga gagtgttaac
    10561 agattcagca gaattcaacc gcgtattagg tggaggtatt gtgagcggat cgttagtact
    10621 tattggtggg gatccaggta ttggtaagtc aacgttactt ttacaaattt gtgcatcgtt
    10681 atctcaaaag aaaaaagtac tatatattac tggagaagaa tcgcttagtc agactaaatt
    10741 acgtgcagag cgattagatg aagattcaag tgaattgcaa gtattagctg aaacagatct
    10801 tgaagttatt tatcaaacag taaaagaaga acaacctgat ttactagtag tggattcgat
    10861 tcaaacaata tatcatcctg aaatcagctc tgcgccaggt tctgtttcac aagttcgtga
    10921 aagtacacaa agtttaatga atattgctaa acaaatgaac attgcaactt ttatagtggg
    10981 tcatgtaacg aaagaaggtc aaattgctgg cccaagattg ctagaacaca tggttgatac
    11041 tgtgctttat tttgaaggcg atgaacacca cgcatatcga attttgcgag ctgttaaaaa
    11101 ccgttttggt tcaacgaatg aaatgggaat cttcgaaatg aagcaaagtg gattaaaagg
    11161 tgtaaataat ccatctgaaa tgtttttaga agaacgttca acaaatgttc caggttcaac
    11221 aattgttgca accatggagg gaaccagacc acttttaata gaagttcaag cgctggtaac
    11281 tccaacgact tttaacaatc cgagacgaat ggcaacaggg attgatcata atcgattaag
    11341 tttgttgatg gctgttttgg aaaagaaaga aaattatcta ttacaacaac aagatgctta
    11401 tatcaaagta gctggcggtg taaagttaac ggagccagca gttgatttaa gtgtaattgt
    11461 agcaactgcg tctagcttta aagatgaagc tgtcgacgga ttagattgct atattggaga
    11521 agttggttta acgggtgagg tacgtcgtgt atctcggata gaacaacgcg tgcaagaggc
    11581 tgcaaaacta ggtttcaaac gtgtaattat tcctaaaaat aatataggcg gatggacata
    11641 tcctgaaggt atacaagtaa taggtgtaac tactgtacat gaagcattgt catttgctct
    11701 tcattcataa aacatcaaga aaggaggaca ttgtgtgaat atcgttaaac taatggttat
    11761 tattatttac ttaattattg ggagcgcatt aggaataatt attattcctg aaattgcaaa
    11821 tgatcttgga ttacaaaact ccagcttttt aaaaaatcac tatgtagatg gcattatcgg
    11881 tagtattttt atgttcttaa tttttggtgt atttattaga cgagttacta acgctataaa
    11941 aggtttagaa cattttatta tgcgtagaag tgctgttgaa atactatttg caacaatagg
    12001 tttaataatc ggattactta tttctgttat ggtgtcgttt atattagaat caattggcaa
    12061 ctctattttt aatcatttca ttcctgtcat aattacgata ttactatgtt atttcggttt
    12121 ccaatttggc cttaaaaaac gagatgaaat gttaatgttt ttacctgaga atatagcgcg
    12181 ttccatgtca caacatacta aaagtgctac gccaaaaatt atcgacacaa gcgcaattat
    12241 tgatggtcgt attttagaag tcattcgttg cggttttatc gatggcaata ttttaattcc
    12301 acaaggtgtt attaatgaat tacaaattgt tgcagattca aatgacagtg ttaaacgtga
    12361 aaagggtaaa agaggcttag atattttaaa tgaattgtat gatttagatt atcctacaaa
    12421 agtcatacat ccaactaaaa cacatagtga tattgataca atgttattaa agctagctaa
    12481 acaatatcat gcaagtatta ttacgacaga tttcaaccta aataaagttt gtcatgtaca
    12541 tggtatcaaa gcattaaatg ttaatgattt atcagaagca atcaaaccta atgtacatca
    12601 aggtgatcaa ctgcatattt tactgacaaa aatgggtaaa gagcctggtc aggcagtagg
    12661 atatctagat gatggtacga tggtagttgt tgataatgct aaaaatctta ttggcagtca
    12721 tgtcaattta gaagtagtca gcttattgca aacatcttca ggaagaattg tttttgctaa
    12781 aaaaatcgaa gatacagtat cattataaaa actgtagttg acgaaaacaa aatagatatt
    12841 aaaaggtata tgaaatggcg aagtttgtaa tttgaagtat aactataaat aaatgcaaaa
    12901 cataatagtt atcaaaaaat acaaatagtg ctaatatatc attgaaacaa gttcattaag
    12961 tgttaaattt tagatattaa taaagttatt cttatagcaa tcaagacata caaaattaga
    13021 atcaatttta acgtatttga atagttaatt tgaagtttaa tttcacagta cataatattc
    13081 atttttaagt cgttgaaatg tttatgtagt gcagtcttga ttcttaggga tagctttttt
    13141 aaagtgttga aaaaacaact gctttctatt taaaatttaa gcatattacc cagggaatta
    13201 tgttatgatt aaacaatgaa attattttaa ggtcatgtta aaaagcattg tttcgtttta
    13261 acaataagac gagttagaca tttgttatga cggtcgaaga tagcaaatga acaatttata
    13321 tgaactaact tgaaaatctg atatttaatt taggagtgaa aaaaatgagc gatcgtataa
    13381 gagtaagata tgcaccaagt ccaactggtt atcttcatat tggtaatgca agaacagcat
    13441 tattcaatta cttgtatgct aaacattaca acggagattt tgtgattcga attgaagata
    13501 ctgataaaaa acgtaattta gaagatggag aaacatcaca atttgataat cttaaatggt
    13561 taggattaga ttgggatgag tctgtagata aagacaatgg ctacggacca tatcgtcaat
    13621 ctgaacgtca acatatctac caaccattaa tagatcagtt actagcagaa gataaagcat
    13681 ataaatgcta tatgacagaa gaagaattag aagctgaacg tgaagcgcaa atcgctcgtg
    13741 gtgaaatgcc tcgctatggt ggtcaacatg cgcatttgac tgaagaacaa cgtcaacaat
    13801 ttgaagcaga aggacgccaa ccatcaattc gtttccgagt acctcaaaac caaacgtatt
    13861 catttgatga tatggtaaaa ggaaatattt catttgattc aaatggtatt ggtgactggg
    13921 ttatcgtaaa aaaagatggc attccaacgt acaattttgc agtagctata gatgatcatt
    13981 acatgcaaat ttcagatgta attcgtggtg atgatcatat ttcaaacacg cctaaacaaa
    14041 ttatgattta tgaagcattt ggctgggagc cacctcgttt tggtcatatg tcattaattg
    14101 ttaatgaaga acgtaaaaag ttaagtaaac gtgatgggca aattttacaa tttattgagc
    14161 aatatcgtga cttaggttat ttacctgaag cgttatttaa ttttattgcg ttattaggtt
    14221 ggtctcctga aggtgaagaa gaaatctttt ctaaagaaga atttatcaaa atctttgatg
    14281 aaaagcgttt gtcaaaatca ccagcatttt tcgataagca aaaattagca tgggttaata
    14341 accaatatat gaaacaaaaa gatactgaaa cagtattcca attagcatta cctcatttaa
    14401 ttaaagcaaa tttgattcct gaggtgccgt cagaagagga tttatcttgg ggacgcaaat
    14461 taattgcgct ttatcaaaaa gaaatgagtt atgccggtga aattgtacct ttatcagaaa
    14521 tgttctttaa agaaatgcca gctcttggtg aagaagaaca acaagtgatt aatggagagc
    14581 aagtaccaga gttaatgacg cacttattca gtaaattaga agtacttgaa ccatttgaag
    14641 cggctgaaat taaaaagaca attaaagaag ttcaaaaaga aacaggaata aaaggcaagc
    14701 aattatttat gcctattcgt gttgctgtaa caggccaaat gcatggtcct gaattaccaa
    14761 atacaattga agtacttggt aaagaaaaag tgctaaaccg tttaaaacaa tataagtaat
    14821 gaaatagaca agatcaaggt agtatatact tgaattttat aacgtaacca catatgataa
    14881 agttgtatta acaaattaca acaatatgaa taaagtattt tatataaaac gaaggattag
    14941 taattaaatt tatacgatgc agagagtgta cggttgctgt gagtacaacg tagaaattaa
    15001 tgaatgcacc ttcgtaaaat gaattaaata tataatgaga gtgatgagca ttaagttgac
    15061 ttagtttcct tgataatttg gaagcgcccg caatattatt aatgttattc gctaaattca
    15121 gagtggaacc gtgcggaagc gcctctaaca atacaatttg tatgttagtg gtgctttttt
    15181 gatatttaat ttcgcaggta cttcaattat gtatttacgt agttcaatca ttgaggagga
    15241 aatgatcttg ttaaaaagaa tgagagacga tataaaaatg gtatttgagc aggatccagc
    15301 ggcacgttca acattagaag tcattacaac gtatgcaggt ttacatgcag tttggagtca
    15361 tttgattgca cataagttat acaaccaaaa aaaatatgtt gcagcacgcg cgatatctca
    15421 aatttcaaga tttttcacag gtatagaaat ccatccaggt gctaaaattg gaaagcgtct
    15481 atttatagat catggtatgg gcgttgtaat aggagaaaca tgtacaattg gtgataatgt
    15541 gacaatctat caaggcgtga cacttggtgg gacagggaaa gaaagaggga aaagacaccc
    15601 agatatagga gacaatgttt taatagcagc cggtgcgaaa gttttaggaa atattaaaat
    15661 aaattcaaat gtaaatattg gtgcaaattc agttgtttta caatcagttc caagttattc
    15721 aacggttgtt ggtataccag gacatattgt taagcaagat ggtgttcgag ttggaaaaac
    15781 atttgatcat cgccatctac ctgatccaat ttatgaacaa attaagcatt tagaacgaca
    15841 acttgaaaag actaggaatg gagagattca agatgattac attatataat acgcttacac
    15901 gtcaaaaaga agtgttcaag cctatagaac cagggaaagt aaaaatgtat gtatgtggtc
    15961 ctactgtata taactacatt catattggta acgcaagacc agcaattaat tatgacgtag
    16021 tgagacgtta ctttgaatac caaggatata atgtagaata tgtatcaaat tttacagacg
    16081 tagatgataa attaattaaa cgttctcaag aattaaatca gtctgttccc gaaattgcag
    16141 aaaaatatat cgctgctttt catgaagatg ttggtgcgtt aaatgttaga aaagcgactt
    16201 caaatccaag ggtaatggac catatggatg acattattca atttattaaa gatttggtgg
    16261 atcaaggtta tgcatatgaa agtggtggcg atgtttactt tagaacacgt aaatttgaag
    16321 gttatggtaa attaagtcat caatccatag atgacttaaa agtgggtgct cgtatagatg
    16381 caggagagca taaagaagat gcacttgatt ttacattgtg gaaaaaagcg aagcctggcg
    16441 agattagttg ggatagccca tttggtgaag gtagaccagg atggcatata gaatgttctg
    16501 taatggcatt tcatgagcta ggacctacaa ttgatataca tgcgggtggt tcagatttac
    16561 aatttccaca tcatgaaaat gaaatagcac aatcagaagc acataatcat gcgccatttg
    16621 ctaattattg gatgcataat ggtttcatta atattgataa tgaaaaaatg agtaaatcac
    16681 taggcaactt tattttagtt cacgatatta ttaaagaagt tgatccagat gtactaagat
    16741 tctttatgat tagcgtacat tatagaagcc caattaacta taatctagaa ttggtagaat
    16801 cagcacgtag tggactagag cgtattcgca atagttatca attaattgaa gagcgcgcac
    16861 aaattgctac taatattgaa aatcaacaga catatattga tcaaattgat gcgattttaa
    16921 atcgttttga aacagttatg aatgatgatt ttaatacagc taatgcaatt acagcttggt
    16981 atgatttagc aaaacttgcg aataaatatg tactagagaa tacaacatca acagaagtaa
    17041 ttgataaatt taaagcagtt tatcaaattt tcagcgatgt tttaggtgta ccgttaaaat
    17101 ctaaaaatgc agatgaatta ttggatgaag atgttgaaaa attaatcgaa gagcgtaatg
    17161 aagcaaggaa aaacaaagat tttgcacgag cagatgaaat tcgagacatg ctgaaatcac
    17221 aaaacattat attagaagac acacctcaag gggttagatt taaacgtgga taatcaacaa
    17281 gataatcaca ttaaattatt gaatccattg accttagcat atatgggaga cgcagtctta
    17341 gatcaatatg tacgtaccta tatcgtttta aagcttaaaa gtaagcctaa taaactacat
    17401 caaatgtcta aaaaatatgt atctgccaaa agtcaggcgc aaacgttaga atatttaatg
    17461 gagcaagaat ggtttacaga cgaagaaatg gatattttga agcgagggcg taacgcgaaa
    17521 agtcatacta aagctaaaaa cactgatgtt caaacatatc gtaaaagttc agcgatagaa
    17581 gcagtgatag gttttcttta tttagaaaaa agagaagaac gattagaggc attattaaat
    17641 aaaataataa caatagtaaa cgaaaggtag tgacgatgtg gaagatacgg ttattgttgg
    17701 taggcatgct gttagagaag cgattattac tgggcatccg ataaataaga tattgattca
    17761 agaaggtatt aaaaagcaac aaattaatga aattttaaaa aatgcaaaag atcaaaaaat
    17821 cattgttcaa actgtaccaa aatctaaatt agatttttta gcaaatgcac cacatcaggg
    17881 tgttgcagcg cttattgcac catatgaata tgctgacttc gatcaatttt taaaacagca
    17941 aaaagaaaaa gaaggtttat cgacagtact tatattagac ggcttagaag acccgcataa
    18001 cttgggatca attttaagaa cagccgatgc aacgggagtt gatggtgtta ttattcctaa
    18061 acgtcgttca gttacactaa cgcaaacagt tgcaaaagcc tcaacaggtg caattgaaca
    18121 tgtaccagtt attcgagtga caaatttagc taaaactatc gatgaactaa aagataatgg
    18181 cttttgggta gctggcactg aagctaataa tgcaacagat tatagaaatc tagaagcgga
    18241 catgtcattg gctattgtaa ttggtagcga aggacagggt atgagtcgcc tagtaagtga
    18301 taaatgcgat ttttatatta agattccaat ggttggacat gtaaacagtt tgaatgcttc
    18361 ggttgcagca agtttaatga tgtacgaagt atttcgaaaa agacatgatg ttggagaaat
    18421 ataatgaaag aacgttactt aatcattgat ggatacaata tgataggaca atcaccaacg
    18481 ctaagcgcca ttgcaaaaga gaatttagaa gaagctagaa tacaattaat agatgcaatt
    18541 gcaaattata atgcagttat ttcagatgaa attatttgtg ttttcgatgc ttatgaccaa
    18601 tcgggtgttg aaagagaata catgtatcat ggcgttaaaa cgatttttac caaggaaaaa
    18661 gaaacagctg atagtttcat agaacgttat gtttatgaac tttatgacaa gcatactaag
    18721 catattacag ttgtaacaag tgatatgagt gagcaacatg ctatctttgg atcaggtgca
    18781 tatagaatat catctcgcga aatgtggaga gatttaaaag aaaatgaaat tgatgtgagt
    18841 aaatcattag atgatataag tgaaaacaag ccaagaactc gaattccgtt atcttctgaa
    18901 atccttgcag aatttgaaaa aatacgaaga ggacatcata agaaatgaca tttccgtcat
    18961 cttgaaattt tgaatgtaac aatattaaac taaccttaaa ttttagatag aaggggttag
    19021 tttaatactt gaaatatgat ttgacaactc aagacagtac aatcaaacgt aacaatgcaa
    19081 taaatgataa agacttcgaa aagttagtaa tggatctaca accattaatt attcgacgca
    19141 tcaaaacatt tggatttaat cattatgatt tagaagactt atatcaagaa atacttatac
    19201 ggatgtatag gtcggtccaa acatttgatt ttagtggaga gcagcctttc acaaattatg
    19261 ttcaatgttt aattacgtct gtaaagtatg attatttgag aaaatattta gctacaaata
    19321 aaagaatgga taatttgatt aatgaatata gagttacgta tccatgtgca ataaagcgtt
    19381 ttgatgttga aaacaattat ttgaataaat tagcaattaa agagttgatt tgtcagttta
    19441 agtatttgag tgcatttgaa aaagatgtca tgtatttaat gtgtgaacaa tataagccga
    19501 gagaaattgc tcaattgatg catgtaaaag agaaagtgat ttataatgcc atacaacgat
    19561 gtaaaaataa aataaaacgt tatttcaaaa tgatttgaaa agcgccttag gacgtgaatt
    19621 gaattataac gtgttactta ctgatggttt gacatttgtt ataaatttta tgtatagtat
    19681 actggtatta taatgaataa aggtgaatta ttgtgagaaa aataccttta aattgtgaag
    19741 cttgtggcaa tagaaattat aatgttccta agcaagaagg ctcggcaaca agattaacct
    19801 taaagaaata ttgtccaaaa tgtaacgcgc acacaattca taaagaatcg aaataaatac
    19861 attcgaaata atactttgat aatatgttca aaggatttgg aggttgagca gatggctaaa
    19921 aaagaaagtt tctttaaagg cgttaagtct gaaatggaaa aaacaagttg gccgacgaaa
    19981 gaagagctat ttaaatatac tgtaattgta gtttctactg ttatattctt cttagtcttt
    20041 ttctatgcct tagatttagg aattacagca ttgaaaaatt tattatttgg ttagaggagt
    20101 gaagacatgt ctgaagaagt tggcgcaaag cgttggtatg cagtgcatac atattctgga
    20161 tatgaaaata aagttaaaaa gaatttagaa aaaagagtag aatctatgaa tatgactgaa
    20221 caaatcttta gagtagtcat accggaagaa gaagaaactc aagtaaaaga tggcaaagct
    20281 aaaacgactg ttaaaaaaac attccctgga tatgtcttag tggaattaat catgacagat
    20341 gaatcatggt atgtggtaag aaatacacca ggtgttactg gttttgtagg ttctgcaggt
    20401 gcagggtcta agccaaatcc attgttacca gaagaagttc gcttcatctt aaaacaaatg
    20461 ggtcttaaag aaaagactat cgatgttgaa ctcgaagttg gcgagcaagt tcgtattaaa
    20521 tcaggtccat ttgcgaatca agttggtgaa gttcaagaaa ttgaaacaga taagtttaag
    20581 ctaacagtat tagtagatat gtttggccga gaaacaccag tagaagttga attcgatcaa
    20641 atagaaaagc tttaattaac aattaaagtt attaaactaa ccaaaagata aaaaagagta
    20701 ttgatttttt aattagaaaa gtgttaaaat tatgtggtcg cgcttttaga gcgcccattt
    20761 cgtcacgaaa tgttaagagt gggagggcaa aactgagccc tgtgaccaca tcacgatatc
    20821 aaggaggtgc acatcgtggc taaaaaagta gataaagttg ttaaattaca aattcctgca
    20881 ggtaaagcga atccagcacc accagttggt ccagcattag gtcaagcagg tgtgaacatc
    20941 atgggattct gtaaagagtt caatgcacgt actcaagatc aagcaggttt aattattccg
    21001 gtagaaatca gtgtttatga agatcgttca tttacattta ttacaaaaac tccaccggct
    21061 ccagtattac ttaaaaaagc agctggtatt gaaaaaggtt caggcgaacc aaacaaaact
    21121 aaagttggta cagtaactaa agatcaagta cgcgaaattg ctaacagcaa aatgcaagac
    21181 ttaaacgctg ctgacgaaga agcagctatg cgtattatcg aaggtactgc acgtagtatg
    21241 ggtatcgttg tagaataatt ttacgaatat taaatttgat tacatgattt aaacgatgaa
    21301 gcagataaca gagataataa tgatgaatta taaatataat ctgaatgact agattaatga
    21361 ttgatttatt cataagatta attcttctgt tgtctgctct taacttgcat atagcaagta
    21421 atgtgggagg aaattccgct aaaaccacta aaggaggaac tataaatggc taaaaaaggt
    21481 aaaaagtatc aagaagcagc tagtaaagtt gaccgtactc agcactacag tgttgaagaa
    21541 gcaattaaat tagctaaaga aacaagcatt gctaactttg acgcttctgt tgaagttgca
    21601 ttccgtttag gaattgatac acgtaaaaat gaccaacaaa tccgtggtgc agttgtatta
    21661 ccaaacggaa ctggtaaatc acaaagtgta ttagtattcg ctaaaggtga caaaattgct
    21721 gaagctgaag cagcaggtgc tgactatgta ggtgaagcag aatacgttca aaaaatccaa
    21781 caaggttggt tcgacttcga tgtagtagtt gctacaccag acatgatggg tgaagttggt
    21841 aaattaggtc gtgtattagg accaaaaggt ttaatgccaa accctaaaac tggaactgta
    21901 acaatggatg ttaaaaaagc tgttgaagaa atcaaagctg gtaaagtaga atatcgtgct
    21961 gaaaaagctg gtatcgtaca tgcatcaatt ggtaaagttt catttactga tgaacaatta
    22021 attgaaaact tcaatacttt acaagatgta ttagctaaag ctaaaccatc atctgctaaa
    22081 ggtacatact tcaaatctgt tgctgtaact acaacaatgg gtcctggagt taaaattgat
    22141 actgcaagtt tcaaataata aataatataa acaattacag gctgaaagaa atatctttca
    22201 gtctgtaaaa atatattgac aataagtaat ttccaagtta tattacttat tgtgattatt
    22261 ttacctaaga cagtaggagt tatttataac ttaaaattta tcctgccgag gctaaaattg
    22321 acttgaacgt gatgatctat gatctttcaa gcactttttg ccgtgggtag aaagtgcttt
    22381 ttttattaat tttaaaaaaa gcaccaaaaa tttaaatgga ggtgtctgaa tgtctgctat
    22441 cattgaagct aaaaaacaac tagttgatga aattgctgag gtactatcaa attcagtttc
    22501 aacagtaatc gttgactacc gtggattaac agtagctgaa gttactgact tacgttcaca
    22561 attacgtgaa gctggtgttg agtataaagt atacaaaaac actatggtac gtcgtgcagc
    22621 tgaaaaagct ggtatcgaag gcttagatga attcttaaca ggtcctactg ctattgcaac
    22681 ttcaagtgaa gatgctgtag ctgcagcgaa agtaatttct ggatttgcta aagatcatga
    22741 agcattagaa attaaatcag gcgttatgga aggcaatgtt attacagcag aagaagttaa
    22801 aactgttggt tcattacctt cacacgatgg tcttgtatct atgcttttat cagtattaca
    22861 agctcctgta cgcaacttcg cttatgcggt taaagctatt ggagaacaaa aagaagaaag
    22921 cgctgaataa tttttagcgt aaaaaaatta aaaataatgg aggaattata aaatggctaa
    22981 tcatgaacaa atcattgaag cgattaaaga aatgtcagta ttagaattaa acgacttagt
    23041 aaaagcaatt gaagaagaat ttggtgtaac tgcagctgct ccagtagcag tagcaggtgc
    23101 agctggtggc gctgacgctg cagcagaaaa aactgaattt gacgttgagt taacttcagc
    23161 tggttcatct aaaatcaaag ttgttaaagc tgttaaagaa gcaactggtt taggattaaa
    23221 agatgctaaa gaattagtag acggagctcc taaagtaatc aaagaagctt tacctaaaga
    23281 agaagctgaa aaacttaaag aacaattaga agaagttgga gctactgtag aattaaaata
    23341 attcaagtat cttaaactta ataatcaaag ttttatagca agtattgcta taatataatg
    23401 attctttgag aagttaaaac cccgttattt tgataacggg gttttattca tttaaagact
    23461 gagtgaaatg ttataattat aatgacgagt tacaaagtga agatgaggtg gaataatgag
    23521 tcattattac gatgaagatc caagtgtaat tagcaatgaa caacgtattc aatatcaatt
    23581 aaaccatcat aaaattgatt taataactga taatggagtg ttttcgaaag ataaagtaga
    23641 ttatggttca gatgttcttg ttcaaacttt tttaaaagcg catccacctg gtccaagtaa
    23701 gcgaattgcc gatgttggtt gtggttacgg accaattggt ttgatgattg ctaaagtatc
    23761 accacatcat tcaattacaa tgctagatgt taatcacaga gcgctagcct tagttgaaaa
    23821 aaacaaaaaa ataaatggta ttgataatgc gatcgtaaag gaaagtgatg ctttgtctgc
    23881 tgtggaagac aaaagttttg attttatttt aaccaatcca ccaataagag cagggaaaga
    23941 aaccgtgcat cgtatattcg agcaagcatt acatagatta gactcgaacg gtgaactatt
    24001 cgttgtaatt cagaagaagc aaggtatgcc atctgcaaag aaaagaatga atgaactttt
    24061 tggaaatgta gaagtggtaa ataaagataa aggatattac attctgagaa gtataaaagc
    24121 ttgaaatgaa atggatattc tgttatagtt atacaatgta aaaatttatg ttcaataagt
    24181 gtgtactttt acgttaaata gataagttaa ttaagaataa atatagaatc gaaaatggtg
    24241 tcatcattag tgttgccgtt ttctttttgt ctttttatta atatgcttat ggtatttagc
    24301 taaaagcgga tcacataatt tttgaggggt gaatctgttt ggcaggtcaa gttgtccaat
    24361 atggaagaca tcgtaaacgt agaaactacg cgagaatttc agaagtatta gaattaccaa
    24421 acttaataga aattcaaact aaatcttacg agtggttcct aagagaaggt ttaatcgaaa
    24481 tgtttagaga catttctcca attgaagatt ttactggtaa tttgtcatta gagtttgtgg
    24541 attaccgttt aggagaacca aaatatgatt tagaagaatc taaaaaccgt gacgctactt
    24601 atgctgcacc tcttcgtgta aaagtgcgtc taatcattaa agaaacagga gaagttaaag
    24661 aacaagaagt ctttatgggt gatttcccat taatgactga tacaggtacg ttcgttatca
    24721 atggtgcaga acgtgtaatc gtatctcaat tagttcgttc accatccgtt tatttcaatg
    24781 aaaaaatcga caaaaatggt cgtgaaaact atgatgcaac aattattcca aaccgtggtg
    24841 catggttaga atatgaaaca gatgctaaag atgttgtata cgtgcgtatt gatagaacac
    24901 gtaaactacc attaacagta ttgttacgtg cattaggttt ctcaagcgac caagaaattg
    24961 ttgacctttt aggtgacaat gaatatttac gtaatacttt agagaaagac ggcactgaaa
    25021 acactgaaca agcgttatta gaaatctatg aacgtttacg tccaggtgaa ccaccaactg
    25081 ttgaaaatgc taaaagtcta ttgtattcac gtttctttga tccaaaacgc tatgacttag
    25141 caagcgtggg tcgttataaa acaaacaaaa aattacattt aaaacatcgt ttatttaatc
    25201 aaaaattagc tgagccaatt gtaaatactg aaactggtga aattgtagtt gaagaaggta
    25261 cagtgcttga tcgtcgtaaa atcgacgaaa tcatggatgt acttgaatca aatgcaaaca
    25321 gcgaagtgtt tgaattgcat ggtagcgtta tagacgagcc agtagaaatt caatcaatta
    25381 aagtatatgt tcctaacgat gatgaaggtc gtacgacaac tgtaattggt aatgctttcc
    25441 ctgactcaga agttaaatgc attacaccag cagatatcat tgcttcaatg agttacttct
    25501 ttaacttatt aagcggtatt ggatatacag atgatattga ccatttaggt aaccgtcgtt
    25561 tacgttctgt aggtgaatta ctacaaaacc aattccgtat cggtttatca agaatggaaa
    25621 gagttgtacg tgaaagaatg tcaattcaag atactgagtc tatcacacct caacaattaa
    25681 ttaatattcg acctgttatt gcatctatta aagaattctt tggtagctct caattatcac
    25741 aattcatgga ccaagcaaac ccattagctg agttaacgca taaacgtcgt ctatcagcat
    25801 taggacctgg tggtttaaca cgtgaacgtg ctcaaatgga agtacgtgac gttcactact
    25861 ctcactatgg ccgtatgtgt ccaattgaaa cacctgaggg accaaacatt ggattgatta
    25921 actcattatc aagttatgca cgtgtaaatg aattcggctt tattgaaaca ccatatcgta
    25981 aagttgattt agatacacac gctatcactg atcaaattga ctatttaaca gctgacgaag
    26041 aagatagcta tgttgtagca caagcaaact ctaaattaga tgaaaatggt cgtttcatgg
    26101 atgatgaagt tgtatgtcgt ttccgtggta acaacacagt tatggctaaa gaaaaaatgg
    26161 attatatgga tgtatcgccg aagcaagttg tttcagcagc gacagcatgt attccattct
    26221 tagaaaatga tgactcaaac cgtgcattga tgggtgcgaa catgcaacgt caagcagtgc
    26281 ctttgatgaa tccagaagca ccatttgttg gtacaggtat ggaacacgtt gcagcacgtg
    26341 attctggtgc ggctattaca gctaagcaca gaggtcgtgt tgaacatgtt gaatctaatg
    26401 aaattcttgt acgtcgtcta gttgaagaga acggcgttga gcatgaaggt gaattagatc
    26461 gctatccatt agctaaattt aaacgttcaa actcaggtac atgttataac caacgtccaa
    26521 tcgttgcagt tggagatgtt gttgagtata acgagatttt agcagacgga ccatctatgg
    26581 aattaggaga aatggcatta ggtagaaacg tagtagttgg tttcatgact tgggacggtt
    26641 acaactatga ggatgccgtt atcatgagtg aaagacttgt gaaagatgac gtgtatactt
    26701 ctattcatat tgaagagtat gaatcagaag cacgtgatac taagttagga cctgaagaaa
    26761 tcacaagaga tattcctaat gtttctgaaa gtgcacttaa gaacttagac gatcgtggta
    26821 tcgtttatat tggtgcagaa gtaaaagatg gagatatttt agttggtaaa gtaacgccta
    26881 aaggtgtaac tgagttaact gccgaagaaa gattgttaca tgcaatcttt ggtgaaaaag
    26941 cacgtgaagt tagagatact tcattacgtg tacctcacgg cgctggcggt atcgttcttg
    27001 atgtaaaagt attcaatcgt gaagaaggcg acgatacatt atcacctggt gtaaaccaat
    27061 tagtacgtgt atacatcgtt caaaaacgta aaattcatgt tggtgataag atgtgtggtc
    27121 gacatggtaa caaaggtgtc atttctaaga ttgttcctga agaagatatg ccttacttac
    27181 cagacggacg tccgatcgat atcatgttaa accctcttgg tgtaccatct cgtatgaaca
    27241 tcggacaagt attagagcta cacttaggta tggctgctaa aaatcttggt attcacgttg
    27301 catcacctgt atttgacggt gcaaacgatg acgatgtatg gtcaacaatt gaagaagctg
    27361 gtatggctcg tgatggtaaa actgtacttt atgatggacg tacaggtgaa ccattcgata
    27421 accgtatttc agtaggtgta atgtacatgt tgaaacttgc gcacatggtt gatgataaat
    27481 tacatgcgcg ttcaacagga ccatattcac ttgttacaca acaaccactt ggcggtaaag
    27541 cgcaattcgg tggacaacgt ttcggtgaga tggaggtatg ggcacttgaa gcatatggtg
    27601 ctgcatacac attacaagaa atcttaactt acaaatccga tgatacagta ggacgtgtga
    27661 aaacatacga ggctattgtt aaaggtgaaa acatctctag accaagtgtt ccagaatcat
    27721 tccgagtatt gatgaaagaa ttacaaagtt taggtttaga tgtaaaagtt atggatgagc
    27781 aagataatga aatcgaaatg acagacgttg atgacgatga tgttgtagaa cgcaaagtag
    27841 atttacaaca aaatgatgct cctgaaacac aaaaagaagt tactgattaa tacgcaattt
    27901 acaaaacagg caaaaagata ctaagctgaa ttttattgat gattcagttt agtactttaa
    27961 gccattttaa ataaatgcaa atcaatcaaa tagcacagct aatctaaatt gaaggaggta
    28021 ggctccttga ttgatgtaaa taatttccat tatatgaaaa taggattggc ttcacctgaa
    28081 aaaatccgtt cttggtcttt tggtgaagtt aaaaaacctg aaacaatcaa ctaccgtaca
    28141 ttaaaacctg aaaaagatgg tctattctgt gaaagaattt tcggacctac aaaagactgg
    28201 gaatgtagtt gtggtaaata caaacgtgtt cgctacaaag gcatggtctg tgacagatgt
    28261 ggagttgaag taactaaatc taaagtacgt cgtgaaagaa tgggtcacat tgaacttgct
    28321 gctccagttt ctcacatttg gtatttcaaa ggtataccaa gccgtatggg attattactt
    28381 gacatgtcac caagagcatt agaagaagtt atttactttg cttcttatgt tgttgtagat
    28441 ccaggtccaa ctggtttaga aaagaaaact ttattatctg aagctgaatt cagagattat
    28501 tatgataaat acccaggtca attcgttgca aaaatgggtg cagaaggtat taaagattta
    28561 cttgaagaga ttgatcttga cgaagaactt aaattgttac gcgatgagtt ggaatcagct
    28621 actggtcaaa gacttactcg tgcaattaaa cgtttagaag ttgttgaatc attccgtaat
    28681 tcaggtaaca aaccttcatg gatgatttta gatgtacttc caatcatccc accagaaatt
    28741 cgtccaatgg ttcaattaga tggtggacga tttgcaacaa gtgacttaaa cgacttatac
    28801 cgtcgtgtaa ttaatcgaaa taatcgtttg aaacgtttat tagatttagg tgcacctggt
    28861 atcatcgttc aaaacgaaaa acgtatgtta caagaagccg ttgacgcttt aattgataat
    28921 ggtcgtcgtg gtcgtccagt tactggccca ggtaaccgtc cattaaaatc tttatctcat
    28981 atgttaaaag gtaaacaagg tcgtttccgt caaaacttac ttggtaaacg tgttgactat
    29041 tcaggacgtt cagttattgc agtaggtcca agcttgaaaa tgtaccaatg tggtttacca
    29101 aaagaaatgg cacttgaact atttaaacca ttcgtaatga aagaattagt tcaacgtgaa
    29161 attgcaacta acattaaaaa tgcgaagagt aaaatcgaac gtatggatga tgaagtttgg
    29221 gacgtattgg aagaagtaat tagagaacat cctgtattac ttaaccgtgc accaacactt
    29281 catagacttg gtattcaagc atttgaacca actttagttg aaggtcgtgc gattcgtcta
    29341 catccacttg taacaacagc ttataacgct gactttgacg gtgaccaaat ggcggttcac
    29401 gttcctttat caaaagaggc acaagctgaa gcaagaatgt tgatgttagc agcacaaaac
    29461 atcttgaacc ctaaagatgg taaacctgta gttacaccat cacaagatat ggtacttggt
    29521 aactattacc ttactttaga aagaaaagat gcagtaaata caggcgcaat ctttaataat
    29581 acaaatgaag tattaaaagc atatgcaaat ggctttgtac atttacacac tagaattggt
    29641 gtacatgcaa gttcattcaa taatccaaca tttactgaag aacaaaacaa aaagattctt
    29701 gctacgtcag taggtaaaat tatattcaat gaaatcattc cagattcatt tgcttatatt
    29761 aatgaaccta cgcaagaaaa cttagaaaga aagacaccaa acagatattt catcgatcct
    29821 acaactttag gtgaaggtgg attaaaagaa tactttgaaa atgaagaatt aattgaacct
    29881 ttcaacaaaa aattcttagg taatattatt gcagaagtat tcaacagatt tagcatcact
    29941 gatacatcaa tgatgttaga ccgtatgaaa gacttaggat tcaaattctc atctaaagct
    30001 ggtattacag taggtgttgc tgatatcgta gtattacctg ataagcaaca aatacttgat
    30061 gagcatgaaa aattagtcga cagaattaca aaacaattca accgtggttt aatcactgaa
    30121 gaagaaagat ataatgcagt tgttgaaatt tggacagatg caaaagatca aattcaaggt
    30181 gaattgatgc aatcacttga taaaactaac ccaatcttca tgatgagtga ttcaggtgcc
    30241 cgtggtaacg catctaactt tacacagtta gcaggtatgc gtggattgat ggccgcacca
    30301 tctggtaaga ttatcgaatt accaatcaca tcttcattcc gtgaaggttt aacagtactt
    30361 gaatacttca tctcaactca cggtgcacgt aaaggtcttg ccgatacagc acttaaaaca
    30421 gctgactcag gatatcttac tcgtcgtctt gttgacgtgg cacaagatgt tattgttcgt
    30481 gaagaagact gtggtactga tagaggttta ttagtttctg atattaaaga aggtacagaa
    30541 atgattgaac catttatcga acgtattgaa ggtcgttatt ctaaagaaac aattcgtcat
    30601 cctgaaactg atgaaataat cattcgtcct gatgaattaa ttacacctga aattgctaag
    30661 aaaattacag atgctggtat tgaacaaatg tatattcgct cagcatttac ttgtaacgca
    30721 cgacatggtg tttgtgaaaa atgttacggt aaaaaccttg ctactggtga aaaagttgaa
    30781 gttggtgaag cagttggtac aattgcagcc caatctatcg gtgaaccagg tacacagctt
    30841 acaatgcgta cattccatac aggtggggta gcaggtagcg atatcacaca aggtcttcct
    30901 cgtattcaag agattttcga agcacgtaac cctaaaggtc aagcggtaat tacggaaatc
    30961 gaaggtgtcg tagaagatat taaattagca aaagatagac aacaagaaat tgttgttaaa
    31021 ggtgctaatg aaacaagatc ataccttgct tcaggtactt caagaattat tgtagaaatc
    31081 ggtcaaccag ttcaacgtgg tgaagtatta actgaaggtt ctattgaacc taagaattac
    31141 ttatctgttg ctggattaaa cgcgactgaa agctacttat taaaagaagt acaaaaagtt
    31201 taccgtatgc aaggtgtaga aatcgacgat aaacacgttg aggttatggt tcgacaaatg
    31261 ttacgtaaag ttagaattat cgaagcaggt gatacgaagt tattaccagg ttcattagtt
    31321 gatattcata actttacaga tgcaaataga gaagcattta aacaccgtaa gcgtcctgca
    31381 acagctaaac cagtattact tggtattact aaagcatcac ttgaaacaga aagtttctta
    31441 tctgcagcat cattccaaga aacaacaaga gttcttacag atgcagcaat taaaggtaag
    31501 cgtgatgact tattaggtct taaagaaaac gtaattattg gtaagttaat tccagctggt
    31561 actggtatga gacgttatag cgacgtaaaa tacgaaaaaa cagctaaacc agttgcagaa
    31621 gttgaatctc aaactgaagt aacggaataa caagtatata acagaggcta atgctttagc
    31681 ctcttgttat ttttatgtaa attatttgat ttaatgttga cgaattctct tgttcaatgt
    31741 taatatatta aaggttgatg caagcagaac tttggaggat aaattattgt ctaaggaaaa
    31801 agttgcacgc tttaacaaac aacattttgt agttggtctt aaagaaacgc ttaaagcgtt
    31861 aaagaaagat caagttacat ctttgattat tgctgaagac gttgaagtat atttaatgac
    31921 tcgcgtgtta agccaaatca atcagaaaaa tatacctgta tcttttttca aaagcaaaca
    31981 tgctttgggt aaacatgtag gtattaacgt caatgcgaca atagtagcat tgattaaatg
    32041 agaattagta agtgttttac ttactaaatt ttatttaacc taaaaatgaa ccacctggat
    32101 gtgtgggatt aaaaagtgaa gagaggagga catatcacat gccaactatt aaccaattag
    32161 tacgtaaacc aagacaaagc aaaatcaaaa aatcagattc tccagcttta aataaaggtt
    32221 tcaacagtaa aaagaaaaaa tttactgact taaactcacc acaaaaacgt ggtgtatgta
    32281 ctcgtgtagg tacaatgaca cctaaaaaac ctaactcagc gttacgtaaa tatgcacgtg
    32341 tgcgtttatc aaacaacatc gaaattaacg catacatccc tggtatcggc cataacttac
    32401 aagaacacag tgttgtactt gtacgtggtg gacgtgtaaa agacttacca ggtgtgcgtt
    32461 accatattgt acgtggagca cttgatactt caggtgttga cggacgtaga caaggtcgtt
    32521 cattatacgg aactaagaaa cctaaaaact aagaatttag tttttaatta aatcttaaac
    32581 ttaaaatatt taatataagg aagggaggat ttacattatg cctcgtaaag gatcagtacc
    32641 taaaagagac gtattaccag atccaattca taactctaag ttagtaacta aattaattaa
    32701 caaaattatg ttagatggta aacgtggaac agcacaaaga attctttatt cagcattcga
    32761 cctagttgaa caacgcagtg gtcgtgatgc attagaagta ttcgaagaag caatcaacaa
    32821 cattatgcca gtattagaag ttaaagctcg tcgtgtaggt ggttctaact atcaagtacc
    32881 agtagaagtt cgtccagagc gtcgtactac tttaggttta cgttggttag ttaactatgc
    32941 acgtcttcgt ggtgaaaaaa cgatggaaga tcgtttagct aacgaaattt tagatgcagc
    33001 aaataataca ggtggtgccg ttaagaaacg tgaggacact cacaaaatgg ctgaagcaaa
    33061 caaagcattt gctcactacc gttggtaaga taaaagcttt taccctgagt gtgttctata
    33121 ttaatgaatt ttcattaagc gttcatgctt agggcatcgc catatctatc gtatttattc
    33181 agtaatataa actggaagga gaaaaaatac atggctagag aattttcatt agaaaaaact
    33241 cgtaatatcg gtatcatggc tcacattgat gctggtaaaa cgactacgac tgaacgtatt
    33301 ctttattaca ctggccgtat ccacaaaatt ggtgaaacac acgaaggtgc ttcacaaatg
    33361 gactggatgg agcaagaaca agaccgtggt attactatca catctgctgc aacaacagca
    33421 gcttgggaag gtcaccgtgt aaacattatc gatacacctg gacacgtaga cttcactgta
    33481 gaagttgaac gttcattacg tgtacttgac ggagcagtta cagtacttga tgcacaatca
    33541 ggtgttgaac ctcaaactga aacagtttgg cgtcaggcta caacttatgg tgttccacgt
    33601 atcgtatttg taaacaaaat ggacaaatta ggtgctaact tcgaatactc tgtaagtaca
    33661 ttacatgatc gtttacaagc taacgctgct ccaatccaat taccaattgg tgcggaagac
    33721 gaattcgaag caatcattga cttagttgaa atgaaatgtt tcaaatatac aaatgattta
    33781 ggtactgaaa ttgaagaaat tgaaattcct gaagaccact tagatagagc tgaagaagct
    33841 cgtgctagct taatcgaagc agttgcagaa actagcgacg aattaatgga aaaatatctt
    33901 ggtgacgaag aaatttcagt ttctgaatta aaagaagcta tccgccaagc tactactaac
    33961 gtagaattct acccagtact ttgtggtaca gctttcaaaa acaaaggtgt tcaattaatg
    34021 cttgacgctg taattgatta cttaccttca ccactagacg ttaaaccaat tattggtcac
    34081 cgtgctagca accctgaaga agaagtaatc gcgaaagcag acgattcagc tgaattcgct
    34141 gcattagcgt tcaaagttat gactgaccct tatgttggta aattgacatt cttccgtgtg
    34201 tattcaggta caatgacatc tggttcatac gttaagaact ctactaaagg taaacgtgaa
    34261 cgtgtaggtc gtttattaca aatgcacgct aactcacgtc aagaaatcga tactgtatac
    34321 tctggagata tcgctgctgc ggtaggtctt aaagatacag gtactggtga tactttatgt
    34381 ggtgagaaaa atgacattat cttggaatca atggaattcc cagagccagt tattcactta
    34441 tcagtagagc caaaatctaa agctgaccaa gataaaatga ctcaagcttt agttaaatta
    34501 caagaagaag acccaacatt ccatgcacac actgacgaag aaactggaca agttatcatc
    34561 ggtggtatgg gtgagcttca cttagacatc ttagtagacc gtatgaagaa agaattcaac
    34621 gttgaatgta acgtaggtgc tccaatggtt tcatatcgtg aaacattcaa atcatctgca
    34681 caagttcaag gtaaattctc tcgtcaatct ggtggtcgtg gtcaatacgg tgatgttcac
    34741 attgaattca caccaaacga aacaggcgca ggtttcgaat tcgaaaacgc tatcgttggt
    34801 ggtgtagttc ctcgtgaata cattccatca gtagaagctg gtcttaaaga tgctatggaa
    34861 aatggtgtct tagcaggtta tcctttaatt gatgttaaag ctaaattata tgatggttca
    34921 taccatgatg tcgattcatc tgaaatggcc ttcaaaattg ctgcatcatt agcacttaaa
    34981 gaagctgcta aaaaatgtga tcctgtaatc ttagaaccaa tgatgaaagt aactattgaa
    35041 atgcctgaag agtacatggg tgatatcatg ggtgacgtaa catctcgtcg tggacgtgtt
    35101 gatggtatgg aacctcgtgg taatgcacaa gttgttaatg cttatgtacc actttcagaa
    35161 atgttcggtt atgcaacatc attacgttca aacactcaag gtcgcggtac ttacactatg
    35221 tacttcgatc actatgctga agttccaaaa tcaatcgctg aagatattat caagaaaaat
    35281 aaaggtgaat aatataactt gttttgacta gctagcctag gttaaaatac aaggtgagct
    35341 taaatgtaag ctatcatctt tatagtttga ttttttgggg tgaatgcatt ataaaagaat
    35401 tgtaaaattc tttttgcatc gctataaata atttctcatg atggtgagaa actatcatga
    35461 gagataaatt taaatattat ttttaattag aataggagag attttataat ggcaaaagaa
    35521 aaattcgatc gttctaaaga acatgccaat atcggtacta tcggtcacgt tgaccatggt
    35581 aaaacaacat taacagcagc aatcgctact gtattagcaa aaaatggtga ctcagttgca
    35641 caatcatatg acatgattga caacgctcca gaagaaaaag aacgtggtat cacaatcaat
    35701 acttctcaca ttgagtacca aactgacaaa cgtcactacg ctcacgttga ctgcccagga
    35761 cacgctgact acgttaaaaa catgatcact ggtgctgctc aaatggacgg cggtatctta
    35821 gtagtatctg ctgctgacgg tccaatgcca caaactcgtg aacacattct tttatcacgt
    35881 aacgttggtg taccagcatt agtagtattc ttaaacaaag ttgacatggt tgacgatgaa
    35941 gaattattag aattagtaga aatggaagtt cgtgacttat taagcgaata tgacttccca
    36001 ggtgacgatg tacctgtaat cgctggttca gcattaaaag ctttagaagg cgatgctcaa
    36061 tacgaagaaa aaatcttaga attaatggaa gctgtagata cttacattcc aactccagaa
    36121 cgtgattctg acaaaccatt catgatgcca gttgaggacg tattctcaat cactggtcgt
    36181 ggtactgttg ctacaggccg tgttgaacgt ggtcaaatca aagttggtga agaagttgaa
    36241 atcatcggtt tacatgacac atctaaaaca actgttacag gtgttgaaat gttccgtaaa
    36301 ttattagact acgctgaagc tggtgacaac attggtgcat tattacgtgg tgttgctcgt
    36361 gaagacgtac aacgtggtca agtattagct gctcctggtt caattacacc acatactgaa
    36421 ttcaaagcag aagtatacgt attatcaaaa gacgaaggtg gacgtcacac tccattcttc
    36481 tcaaactatc gtccacaatt ctatttccgt actactgacg taactggtgt tgttcactta
    36541 ccagaaggta ctgaaatggt aatgcctggt gataacgttg aaatgacagt agaattaatc
    36601 gctccaatcg cgattgaaga cggtactcgt ttctcaatcc gtgaaggtgg acgtactgta
    36661 ggatcaggcg ttgttactga aatcattaaa taatttctaa tttcttagat tttatataaa
    36721 aagaagatcc ctcaatcgag gggtcttttt ttaatgtgta aattttgtaa tggctattcg
    36781 atttagaaga acaataattg atgaaagact gactaataaa acttataact gataatactg
    36841 tttaaataaa attgttgagt cttggacatt gtaaaatgct cccttcaaag ttttcatttt
    36901 ttcaatgtct actttgaagg gagcatttca ttagtttatg tctcagattc atatctttca
    36961 attaatttaa atgcttaatt tgttttaaat acttgctcta attcaatgat ttttaaaaat
    37021 acagctacag cgtattttaa tgatttttca tcaatatcaa atttgggatt atggtgtggc
    37081 gctgtaatac ctttactttc attaccacaa ccagtcagaa agaatgcacc tggtcgtact
    37141 ttcaaataat gtgaaaaatc ttctccaatc atcattaaat ctgattcatt aaagcgtaca
    37201 tgtaagtcat ttgttgcttc tttaataact tgatatgctt tctcgttatt atggacaggc
    37261 aaataccctt taatataatt caaatcatag ttaatatcat ttgctattgc taaaccttgt
    37321 aaaagcttat ccattttgtc cattacatga ttctgtatat ctgaatcgaa agttctaact
    37381 gtacctttac aaaatgcttg atcaggaata acgctatctg tggtgcctgc ttgaatcatt
    37441 ccaaatgaaa gtacagcttg tttaactgga tcgatcgtac gtgaaattat tttttgtgca
    37501 cttaaaatga actctgccat gattactatt gggtcaatgg tttcatgagg tttggcacca
    37561 tgaccgccac gacctttaat tgtgacacta aattcatctg gagaggccat gattgccccc
    37621 gcacgtgaat gaatagttcc agtaggataa ccactccata aatgtgtacc gtaaattcta
    37681 tctacatttt ccagacatcc agcatctatc atttcttgag aaccacctgg catgatttct
    37741 tcaccgtact ggaatattaa tacaacatta ccttctaata aatgtttatg ttcatctaaa
    37801 atctctgcta cagtaagtaa aattgctgta tgaccatcat gcccacacgc atgcatacat
    37861 cctggatttt tagacttata aggcacatcg tttaattcct cgacaggtaa cgcatcaaag
    37921 tcagctctta atgcaatggt aggtcctgtg cccaagcctt taaatgtggc tttgatacca
    37981 ttgcggccga taggagtttc aatatcacaa gataactggc ttaattggtt aacaatataa
    38041 tcatgtgttt gaaattcttc aaaagataac tcaggatatt ggtgtaaata acgtctgagt
    38101 tgaattgttt tattttcttt attatttgct agttggaacc aatctaacac ccttatcact
    38161 actttctaaa ataatgttta tagtataaca ttttatgaaa ttatcgtact aaatgattgc
    38221 tttgagatat tttatctatg aatgataagg ctttcaagtt atgtagaatt actgtatgat
    38281 aaaggtatta ccaaacaata cttaaggggg attatatact gtggttcaat cattacatga
    38341 gtttttagag gaaaatataa attatctaaa agaaaatggt ttgtataatg aaatagatac
    38401 aattgaaggt gcaaacggac cagaaatcaa aatcaatggg aaatcataca ttaacttatc
    38461 ttcaaataat tatttaggac tagcaacaaa tgaagatttg aaatcagctg caaaagcagc
    38521 tattgataca catggtgtag gtgcaggcgc tgttcgtaca atcaatggta cattagattt
    38581 acacgacgaa ttagaagaaa cactagcaaa atttaaagga acagaagctg caatagctta
    38641 tcaatcagga tttaattgta atatggctgc tatttcggct gtgatgaata aaaatgatgc
    38701 tattttatca gatgagctta atcatgcatc aattattgat ggatgtcgct tatctaaagc
    38761 taaaattatt cgagttaacc attcagacat ggatgattta cgtgcgaaag caaaagaagc
    38821 agttgaatca ggtcaataca ataaagtgat gtatatcact gatggcgttt ttagtatgga
    38881 tggtgatgtg gctaaattac ctgaaattgt agaaattgca gaagaatttg gtttattaac
    38941 ttatgttgac gacgctcatg gttcaggtgt tatgggtaaa ggcgctggta cggttaaaca
    39001 ttttggttta caagataaaa tcgatttcca aataggtacg ctttctaaag caattggtgt
    39061 cgttggcggt tatgtagcag gtacaaaaga gttaatagat tggttaaaag cacaatcacg
    39121 accattctta ttctctacat cattagcacc tggggatacc aaagcaataa ctgaagcagt
    39181 taaaaagtta atggattcaa ctgaattaca tgataaatta tgggacaatg cacaatattt
    39241 aaaaaatgga ttgtcaaaat taggatatga tacaggtgag tcagaaactc caattacacc
    39301 agtaattatt ggtgatgaaa aaacaactca agaatttagt aagcgtttaa aagacgaagg
    39361 tgtctatgtg aaatctatcg ttttcccaac agtaccaaga ggtacaggac gtgtaagaaa
    39421 tatgcctaca gctgcacata caaaagacat gttagatgaa gcaattgcgg cttatgaaaa
    39481 agtaggaaaa gaaatgaagt tgatttaata tttatttatt cccacggcaa atattgtcgt
    39541 gggctttttt taatgtttag tttattaaca gtaagttctt ataacaatgt ttagtgctcc
    39601 ccaaaaatta aagtttgaat tttaaaagca tcttgtagaa tttagttgta ttttttacaa
    39661 agaaattcat tttgattatt tttgataatg agcattttaa tagtaataca tgtttatagt
    39721 gtgtagtata tgtctatact agtagtaact atatagagaa agtaggaata aactatgtca
    39781 caagatgtaa atgaattaag taagcaacca acgccagata aagcagaaga taacgcattt
    39841 ttcccatcac catattccct tagtcaatat acagcaacta aaacagattt tgatggtgtt
    39901 gaacacaaag gtgcctataa agatggtaaa tggaaagtat tgatgattgc tgctgaagag
    39961 agatatgtat tattggaaaa tggaaaaatg ttctctacgg gtaatcatcc tgttgaaatg
    40021 ttattacctt tacatcattt aatggaagca ggttttgacg ttgatgttgc gacattatct
    40081 ggttatccag ttaaattaga attatgggct atgccaactg aagacgaggc agttattagt
    40141 acttataata aattgaaaga aaaattaaaa cagccaaaaa aattagcaga tgtgattaaa
    40201 aatgaattag gacctgattc agactattta tctgtcttta tcccaggcgg acatgctgca
    40261 gttgttggta tttctgaaag tgaggacgtt caacaaacat tagattgggc attagacaat
    40321 gaccgcttta tagttacatt atgtcatgga ccagcagcac tactttcagc agggcttaac
    40381 agagaaaaat ctccattaga aggatattct gtttgtgtct tccctgactc attagatgaa
    40441 ggtgcaaata ttgaaatagg ttatttacct ggacgcttga aatggttagt tgctgattta
    40501 ctaactaaac aaggattaaa agtagttaac gacgatatga caggcagaac gttaaaagat
    40561 cgtaaattat taacaggtga cagtccttta gcttcaaatg agttaggaaa attagcagtt
    40621 aatgaaatgt taaatgcaat acaaaataaa taattaaata ttaattagag gagcctcata
    40681 tgtaaatgta tgagggctct tttttttggc aaaatttaag tgatacttgt aaaatagaac
    40741 ctattatgag tatgatttaa gaaaacgctt gcaaaactaa taaccgcaac tagcgatatg
    40801 gaggaaacat gatgtcttat agcattggaa ttgattatgg aacagcttca ggccgtgtgt
    40861 ttttaattaa tacaactaac ggtcaagtag tatcaaaatt tgtgaaacca tatacacatg
    40921 gtgtcattga gagtgaatta aatggtttga aaataccata tacatatgca cttcaaaata
    40981 gtaatgatta tttagaaatt atggaagaag gaatatcata tatagtacgt gaatcaaaaa
    41041 tagatccagt caatatagta ggtattggta tagactttac ttcatctact attattttta
    41101 ctgacgaaaa ccttaacccg gtacataatt taaaacaatt taaaaacaat ccacatgcgt
    41161 atgtgaaact ttggaaacat catggtgcat ataaagaggc agagaaatta tatcaaactg
    41221 ctattgaaaa taataataag tggttaggcc attatggata taatgttagt agtgaatgga
    41281 tgattcccaa aataatggag gtcatgaatc gagcaccaga aattatggaa aaaacggctt
    41341 atattatgga agcgggcgat tggattgtaa ataaattaac taataaaaat gtacgctcga
    41401 attgtggatt aggtttcaaa gcattttggg aagaagaaac agggtttcat tatgatttat
    41461 ttgataaaat agaccccaaa ttatcaaaag taattcaaga taaagtatct gcaccggttg
    41521 ttaatattgg tgaagtagta gggaagctgg acgataaaat ggcacagaaa ttaggattat
    41581 caaaagagac tatggtaagt ccttttatta ttgatgccca tgctagttta ttaggtattg
    41641 ggtctgaaaa agataaagaa atgactatgg tgatgggaac aagcacatgc catcttatgt
    41701 taaatgaaaa gcaacatcaa gtgccaggta tatcaggttc tgtaaaagga gcaattattc
    41761 cagaattatt tgcttatgaa gcgggacaat cagcagtagg tgatttgttt gagtatgtcg
    41821 ctaagcaagc accaaagtca tatgtagatg aagcagcaaa tagaaatatg actgtatttg
    41881 aattaatgaa tgaaaagata aaacatcaaa tgccaggtga aagcgggctc attgctcttg
    41941 attggcataa tggaaatcga agtgtattaa gtgatagcaa tttaacaggt tgtatctttg
    42001 gattaacttt acaaactaag catgaggata tttatagagc atatttagaa gctacagcat
    42061 ttggtactaa gatgattatg caacagtatc aagattggca tatggaagta gaaaaggtat
    42121 ttgcatgtgg cggtatacct aaaaagaatg ctgttatgat ggatatctat gcgaatgtac
    42181 tgaataaaaa attaattgtt atggatagtg agtatgcacc agcaataggc gcagcaatat
    42241 taggtgcagt cagtggtggc gcacataatt caattaatga tgcagttgat gctatgaaag
    42301 agccaatttt atacgaaatt aatccagaag cggaaaaagt acaaaggtat gaaacattat
    42361 ttaaagctta taaggcttta catgatatcc atggttataa aaaagctaat ataatgaaag
    42421 atatccagag tttaagagtt gagggataaa aaatttaatt tgacagtaat tagcaataat
    42481 aaacgctata aattactaaa atcaattaat acaactagaa tttccattta cagaaatatc
    42541 agcaacatgt acatgtcata tatacaagaa agcgctttta tattataatt attatgaaaa
    42601 tgaatattat gtccgcttgt gatggactat agctatatag aagagacaaa ggagatattt
    42661 ctatgaaaaa aattatgatt actggtgcat taggacaaat tggtacagaa ttagttgtta
    42721 agtgcagaga aatttatggg acagataatg ttcttgctac agatattagg gaacctgaag
    42781 cagactcacc tgtacaaaat ggaccatttg aaatcttaga cgtaacagat cgtgaccgta
    42841 tgtttgagtt agttagggac tttgaagcgg atagtctaat gcatatggca gcattattat
    42901 cagcaactgc tgagaaaaat ccaattctag cttgggattt aaatatgggt ggattaatga
    42961 atgcattaga agctgcaaga acttataatt tgcacttttt cacaccaagt tcaattggtg
    43021 catttggaga ctcaactcct aaagttaata cgccacaagt aacgattcag caacctacga
    43081 caatgtatgg tgtaaataaa gtagctggag aattattgtg tcaatactat ttcaaacgtt
    43141 ttggtgtaga tacaagaagt gttagattcc caggtttaat ctcgcatgtt aaagagccag
    43201 gtggcggtac tacagactat gctgttgaaa tatacttcaa agcagtaaga gagggtcatt
    43261 atacaagctt catagataaa ggcacgtata tggatatgat gtatatggat gatgcaattg
    43321 aagcaattat taaacttatg gaagcagacg acgctaaatt agaaactaga aacggttata
    43381 atttgagcgc aatgagtttt gatccagaga tggtaaaaga agcaattcaa gaatactatc
    43441 caaattttac attagattac gatgttgatc ctattagaca aggtatcgct aatagttggc
    43501 cggattctat tgatacaagc tgttcacgtg gcgaatgggg atttgatcct aaatatgatt
    43561 tagcgagcat gactaaatta atgttagaag ctattgaaca aaaagatact gttaaaaata
    43621 ataactaatc atttccattc actttaatac acggaatgat attttaaatt actctttatt
    43681 ttaataaact agtgcatgaa ttctaatatt attcattata cttattgaat tcgcgagctt
    43741 agttcatttt aaagtaaaga gttttttgta tgtaaagtat attagtaaaa cacagattac
    43801 ttgtctctgt gaaattaata cgtttatact aaaagatata gtctttctag aaatctgtta
    43861 attaattttg aatttttaga aaatttgttg aacagcaaaa tatggattgt tataatttaa
    43921 gttaaacaaa ttcttataca atattattag gaggcaatca ccatgtcaca agcagttaaa
    43981 gttgaacgac gagaaacatt aaaacaaaaa ccaaatacat ctcaactagg ttttggtaaa
    44041 tattttactg attatatgtt gagttatgat tatgatgcag aaaaaggatg gcatgatttg
    44101 aagatagtac cttatggtcc tattgaaatt tcacctgctg cacaaggtgt tcattatggt
    44161 caatcggtat tcgaaggatt aaaagcatat aaaaaagatg gggaagttgc acttttccgt
    44221 cctgaagaaa attttaagcg tcttaataac tcgttagcac gattagaaat gcctcaagta
    44281 gacgaagcag aattgttaga ggggctaaaa caattagttg atatagaaag agattggatt
    44341 cctgaagggg aaggtcaatc attatatatt cgtccatttg tttttgcaac agaaggggca
    44401 cttggcgttg gtgcatcaca tcagtataaa ttattaatta ttttatctcc ttcaggtgca
    44461 tattatggtg gtgagacttt aaaaccaact aaaatctatg tagaagatga atatgtacgt
    44521 gctgttcgtg gcggtgtagg ctttgcaaaa gttgcaggta actatgcggc aagtttatta
    44581 gcacaaacta atgcaaataa attaggttat gaccaagtat tatggcttga tggtgttgaa
    44641 cagaaatata tcgaagaagt tggtagcatg aacattttct tcgttgaaaa tggcaaagta
    44701 attacaccag agttgaatgg cagtatttta cctggtatta cacgtaaatc tattatcgaa
    44761 ttagctaaaa acttaggata tgaagtcgaa gagcgccgcg tttcaatcga tgaattattc
    44821 gaatcatatg ataaaggtga gttaacagaa gtatttggta gtggtactgc agcagttatt
    44881 tcacctgtgg gtacattgag atacgaagat cgtgaaatcg ttattaataa taatgagact
    44941 ggtgaaatta ctcaaaaatt atacgacgtc tatactggta ttcaaaatgg tactttagaa
    45001 gataaaaatg gttggagagt cgttgtacca aaatattaat aaaaattgaa tataatcatg
    45061 aaaacaatat gtaaaagtta atcatgacta aaatcccttt caatgaagcg aagcatggta
    45121 ataaattaag tttacaatgt ttattgttaa gtattgaagg ggatttcact tattattata
    45181 tttaattcaa tatttaaata gaacaatact acgagttcat tttcagggga taacgaatat
    45241 catagaatca gcataatacg aaataaataa ataggagtat tgatatcaat ggaatggata
    45301 ttatttgata aagatggtac gttaattgaa tttgatagaa gttgggaaaa aataggggta
    45361 cgatttgtac aatcattgct tgagactttc ccagtacata ataaagaagc tgctttaaga
    45421 caactcggtg tcattaaaga atctattgat ccaaaatcag tgatgggttc aggatcttta
    45481 caacaaatta tccaggcatt taatgatgtg acgggacaag atacaaccga ctggtccaag
    45541 tcaacaagtc aaaagctggt agatgaacgt attcctgaaa ttaattgggt agaaggtgtt
    45601 aaagaagcac ttatcgattt gaaagcaaaa ggctatcaac ttggtattgt tacgagtgat
    45661 actaaaaaag gtgtagaaca atttttagca cataccaatg ctatctcgtt gttcgatttg
    45721 atcatttcta ccgaagcgga tgcctatgag aagccaaatc ctaaagtatt atcgccttta
    45781 tttgagcaat ataatgtaga tcctcagaaa gtagctatag taggagacac tgctaatgat
    45841 atgaagacag caagtaatgc aaatttaggt atggcaatag gtgtattaac aggtattgca
    45901 acaaaagaag aattacatga agctgatatt attttaaata gtgcggcaga tattttagaa
    45961 gctttaaatt aaaaagaaag acatagtgta tatgtgaatt aatgtattcg atagaattga
    46021 taatgtaatc gatgatatct atggaatata cattgaatat aaacatatac gctatgtctt
    46081 tagtctttta tcgtgtatct acttgtcgat atgtttgaat aattcgagca attttgtcta
    46141 tcataggatt taaagattcg gggtccttat ggatatcata ttcattaata ttgatacgta
    46201 caactggaca tgcattaaag ctattaatcc aatcgtcata gcgtttaaat agctttttcc
    46261 agtattcagg gtctgtatta atttccattt cgcgaccacg ttcaataata cgatcaatga
    46321 cctcatcata gttacattct aaataaatca ttacatcagg tttaggaaaa taaggtgtca
    46381 tgaccatggc attaaataag tctgaatatg ttttgaaatc ttctttactc attgtgcctt
    46441 cttcttcatg catttttgca aaaatatcaa catcttcata aattgatcga tcttggacaa
    46501 agccaccacc atattcaaac atacgctttt gttctttaaa acgttcagct aagaagtaaa
    46561 tttgcaaatg gaaactccat cgttcaaaat cgctgtaaaa tttatctaaa tatggattat
    46621 gttcgacatt ttcaaaagac gttttaaagt ttaatttatc tgcaagtgct tgcgttagtg
    46681 ttgattttcc aacaccaact gtacctgcaa tggttataat ggcattttgt ggaataccgt
    46741 aattattcat tggtaatatc tcctatcata ggtaatataa tatgtaatat atcttcgtaa
    46801 tcttgttcat ttttaagaaa atcaatagaa gttgtatcga ttaaaactac atttgaacca
    46861 ttactttgta aggactcata atactcacga taatcttttt ttaactttaa cagatattca
    46921 tcttctattt gatgctcaaa actacggtta cgtttagcaa ttctagattt taacacatca
    46981 aggtctgcat ctaaaaagat aatcatattc ggcataatca tatcttcagt taaaatatca
    47041 taaattttac tgaatttctg aaattcaaca gaactcaaag tatttttagc aaatatctta
    47101 tttttatgta tatgataatc actaactaca ccttgattta gttgtgttac atcttgaaat
    47161 tgcttatatc tattgcataa aaagaacatt tcagtttgaa aactccattt agagatatct
    47221 tcataaaagt ctgataaaaa tggattttct gtgatgattt ctttttcttc ataaaaatct
    47281 aaagtttgac ttaatttgtg tgcaagtgaa gatttaccta cgccaatagg accttcaatt
    47341 gctataaaag gtttgttcat attcacatct ccaaatgtta aaatagacat tgagtattgt
    47401 accataagtg aggtatctgg acataaatga caaatgatat atattttatg acattagcga
    47461 ttgaagaagc taaaaaagca gctcaactag gcgaagtacc tataggtgct atcatcacta
    47521 aagatgatga agttatcgct agagcacata atttaagaga aacactacaa caaccaacgg
    47581 cgcatgctga acatattgca attgaacgtg cagccaaagt gttaggtagt tggcgtttag
    47641 aaggttgcac attatatgta accttagaac catgtgtcat gtgcgcagga acaattgtaa
    47701 tgagtcgcat tccaagagtc gtctatggcg cagatgatcc taaaggtggt tgtagtggca
    47761 gtttaatgaa tttattgcaa caatctaatt ttaatcatcg tgcaattgtt gataaaggtg
    47821 tacttaaaga agcatgtagc acattattaa caacattttt taaaaactta agagccaata
    47881 agaaatccac caattagacg atagtacata ctaattaaaa tttgttagaa ttacattata
    47941 tgataaatta atgacaatat aaatgttaat agaaaagtat gtgcgctgag tatatattct
    48001 tatttaagaa caagatttta aatttacgaa acgaggtaac ataatgataa aactaatagc
    48061 cactgatatg gatggtacgc tacttaatgc agcacatgaa atttctcaac ctaatattga
    48121 tgcgattaaa tacgctcaag aacaagggat aacggttgtt atcgcgacag gtcgagcatt
    48181 ttatgaagca caagcaccag ttgctgacac agatttaaca gtaccatata tttgtttgaa
    48241 tggtgctgaa gtacgtgatg aaactttcaa tgtaatgagc acttcacacc ttaataaatc
    48301 gttagtacac aaaattacaa atgttttaaa agatgcaggt atttattatc aagtatacac
    48361 gagtcgtgcg atttatactg aagatccaca aagagattta gacatttaca tagatattgc
    48421 tgagcgtgca ggtcaacatg caaacgttga gcgtattaaa aatggtattc aaagacgcat
    48481 agataatggt acgttgaaag ttgttgataa ttatgatgct attgaaaaca tacctggtga
    48541 attaattatg aaaatattag catttgatgg aaatttagaa aaaattgaca aagctagtaa
    48601 aattttagct gaatctccga atttagctat atcatcatct tcgagaggaa atatagaaat
    48661 aacgcattca gatgcacaaa aaggtattgc gctagaaaca attgccgaaa gattagggat
    48721 tgaaatgaaa gatgtcatgg caataggtga caatttaaat gacttatcaa tgttagagaa
    48781 agttggctat ccagttgcga tggaaaatgg tgcagaagaa gttaaaaaaa tagcgaaata
    48841 tgtcacagat acgaatgaaa atagtggtgt tggaaaagct attatgaaat tattacgtga
    48901 acaacaagtt taataaaaaa agaggggtca aatatgaaag gattaattat tattggcagt
    48961 gcacaagtga attcacatac aagtgcacta gcaagatact taactgagca ttttaaaaca
    49021 catgatattg aagcggaaat attcgattta gcagaaaaac cgttaaatca attagatttt
    49081 tcaggaacaa caccgtctat tgatgaaatc aaacaaaata tgaaagattt aaaagagaaa
    49141 gcaatggcgg cggacttttt aatattagga acgccaaact atcatggttc atattctgga
    49201 atattgaaaa atgcattaga tcatctaaat atggattatt ttaaaatgaa acctgtaggc
    49261 ttaataggaa atagtggtgg tattgttagt tcagagccat tgtcacattt aagagtaatc
    49321 gtcagaagtt tactaggcat tgctgtacca actcaaatag caacacatga ttctgatttt
    49381 gctaaaaatg aagatggttc atattactta aatgatagtg aattccaatt acgagcaaga
    49441 ttatttgtcg atcaaattgt atcttttgtg aataatagtc catatgaaca tttaaaataa
    49501 tattaaaaaa tatgtaaata tacattaaaa ataggtatgt agcttaaggt atttcattga
    49561 gaatgctttt aagtcacatg cctatttttt gttctaatgc accaatagta agcctttgag
    49621 attactgttg tgagcaatgt tattaattaa aataagatgt aatagcga
//
LOCUS       DAPSKH010000012        48654 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPSKH010000012 DAPSKH010000000
VERSION     DAPSKH010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 48654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48654
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.012"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            19..891
                     /gene="dprA"
                     /locus_tag="RPH49_000798"
     CDS             19..891
                     /gene="dprA"
                     /locus_tag="RPH49_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDY5123984.1"
                     /translation="MIRLFLLKLYWSHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEW
                     VNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYITYMDSEYPVLLKEIYQFPLLLF
                     YKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
                     IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNR
                     IISGLSKGVLITEAKEQSGSHITIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAK
                     VVLNANDIFEDYYI"
     gene            1065..3140
                     /gene="topA"
                     /locus_tag="RPH49_000799"
     CDS             1065..3140
                     /gene="topA"
                     /locus_tag="RPH49_000799"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDY5123985.1"
                     /translation="MTLADNLVIVESPAKAKTIEKYLGKKYKVIASMGHVRDLPRSQM
                     GVDTEDNYEPKYITIRGKGPVVKELKKHAKKAKNVFLASDPDREGEAIAWHLSKILEL
                     EDSKENRVVFNEITKDAVKESFKNPREIEMNLVDAQQARRILDRLVGYNISPVLWKKV
                     KKGLSAGRVQSVALRLVIDRENEIRNFKPEEYWTIEGEFRYKKSKFNAKFLHYKNKPF
                     KLKTKKDVEKITAALDGDQFEITNVTKKEKTRNPANPFTTSTLQQEAARKLNFKARKT
                     MMVAQQLYEGIDLKKQGTIGLITYMRTDSTRISDTAKAEAKQYITDKYGESYTSKRKA
                     SGKQGDQDAHEAIRPSSTMRTPDDMKSFLTKDQYRLYKLIWERFVASQMAPAILDTVS
                     LDITQGDIKFRANGQTIKFKGFMTLYVETKDDSDSEKENKLPKLEQGDKVTATQIEPA
                     QHYTQPPPRYTEARLVKTLEELKIGRPSTYAPTIDTIQKRNYVKLESKRFVPTELGEI
                     VHEQVKEYFPEIIDVEFTVNMETLLDKIAEGDITWRKVIDGFFSSFKQDVERAEEEME
                     KIEIKDEPAGEDCEVCGSPMVIKMGRYGKFMACSNFPDCRNTKAIVKSIGVKCPKCND
                     GDVVERKSKKNRVFYGCSKYPECDFISWDKPIGRDCPKCNQYLVENKKGKTTQVICSN
                     CDYKEAAQK"
     gene            3296..4603
                     /gene="trmFO"
                     /locus_tag="RPH49_000800"
     CDS             3296..4603
                     /gene="trmFO"
                     /locus_tag="RPH49_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HDY5123986.1"
                     /translation="MTQTVNVIGAGLAGSEAAYQLAERGIKVNLIEMRPVKQTPAHHT
                     DKFAELVCSNSLRGNALTNGVGVLKEEMRRLNSIIIEAADKARVPAGGALAVDRHDFS
                     GYITETLKNHENITVINEEINAIPDGYTIIATGPLTTETLAQEIVDITGKDQLYFYDA
                     AAPIIEKESIDMDKVYLKSRYDKGEAAYLNCPMTEDEFNRFYDAVLEAEVAPVNSFEK
                     EKYFEGCMPFEVMAERGRKTLLFGPMKPVGLEDPKTGKRPYAVVQLRQDDAAGTLYNI
                     VGFQTHLKWGAQKEVIKLIPGLENVDIVRYGVMHRNTFINSPDVLNEKYELISQPNIQ
                     FAGQMTGVEGYVESAASGLVAGINLAHKILGKGEVVFPRETMIGSMAYYISHAKNNKN
                     FQPMNANFGLLPSLETRIKDKKERYEAQANRALDYLENFKKTL"
     gene            5020..5916
                     /gene="xerC"
                     /locus_tag="RPH49_000801"
     CDS             5020..5916
                     /gene="xerC"
                     /locus_tag="RPH49_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDY5123987.1"
                     /translation="MNHIQEAFLNTLKVERNFSEHTLKSYQDDLIQFNQFLEQEHLQL
                     NTFEYRDARNYLSYLYSNHLKRTSVSRKISTLRTFYEYWMTLDENIINPFVQLVHPKK
                     EKYLPQFFYEEEMEALFKTVEEDTSKSLRDRVILELLYATGIRVSELVNIKKQDIDFY
                     ANGVTVLGKGSKERFVPFGAYCRQSIENYLEHFKPIQSCNHDFLIVNMKGEAITERGV
                     RYVLNDIVKRTAGVSEIHPHKLRHTFATHLLNQGADLRTVQSLLGHVNLSTTGKYTHV
                     SNQQLRKVYLNAHPRAKKENET"
     gene            5913..6458
                     /gene="hslV"
                     /locus_tag="RPH49_000802"
     CDS             5913..6458
                     /gene="hslV"
                     /locus_tag="RPH49_000802"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDY5123988.1"
                     /translation="MSNTTLHATTIYAVRHNGKAAMAGDGQVTLGQQVIMKQTARKVR
                     RLYEDKVLAGFAGSVADAFTLFEKFETKLQQFSGNLERAAVELAQEWRGDKQLRQLEA
                     MLIVMDKDAILVVSGTGEVIAPDDDLIAIGSGGNYALSAGRALKRHASHLSAEEMAYE
                     SLKVAADICVFTNDNIVVETL"
     gene            6524..7927
                     /gene="hslU"
                     /locus_tag="RPH49_000803"
     CDS             6524..7927
                     /gene="hslU"
                     /locus_tag="RPH49_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDY5123989.1"
                     /translation="MDTAGIRLTPKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLL
                     DEESKQEISPKNILMIGPTGVGKTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVES
                     MVRDLVDVSVRLVKAQKKSLVQDEATAKANEKLVKLLVPSMKKKASQTNNPLESLFGG
                     AIPNFGQNNEDEEEPPTEEIKTKRSEIKRQLEEGKLEKEKVRIKVEQDPGALGMLGTN
                     QNQQMQEMMNQLMPKKKVEREVAVETARKILADSYADELIDQESANQEALELAEQMGI
                     IFIDEIDKVATNNHNSGQDVSRQGVQRDILPILEGSVIQTKYGTVNTEHMLFIGAGAF
                     HVSKPSDLIPELQGRFPIRVELDSLSVEDFVRILTEPKLSLIKQYEALLQTEEVTVNF
                     TDEAITRLAEIAYQVNQDTDNIGARRLHTILEKMLEDLSFEAPSMPNAVVDITPQYVD
                     DKLKSISTNKDLSAFIL"
     gene            7952..8725
                     /gene="codY"
                     /locus_tag="RPH49_000804"
     CDS             7952..8725
                     /gene="codY"
                     /locus_tag="RPH49_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDY5123990.1"
                     /translation="MSLLSKTRELNTLLQKHKGIAVDFKDVAQTISSVTVTNVFIVSR
                     RGKILGSSLNELLKSQRIIQMLEERHIPSEYTERLMEVKQTESNIDIDNVLTVFPPEN
                     RELFIDSRTTIFPILGGGERLGTLVLGRVHDDFNENDLVLGEYAATVIGMEILREKHS
                     EVEKEARDKAAITMAINSLSYSEKEAIEHIFEELGGTEGLLIASKVADRVGITRSVIV
                     NALRKLESAGVIESRSLGMKGTFIKVKKEKFLDELEKSK"
     gene            8776..8868
                     /locus_tag="RPH49_000805"
     CDS             8776..8868
                     /locus_tag="RPH49_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123991.1"
                     /translation="MAVVNEMTLMIMLKSFLYFCLIFNQIDIPH"
     gene            9067..9834
                     /gene="rpsB"
                     /locus_tag="RPH49_000806"
     CDS             9067..9834
                     /gene="rpsB"
                     /locus_tag="RPH49_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDY5123992.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKKVDEAYNFLKQVSEDGGQVLFVGTKKQAQESVKSEAERAGQFYINQRWLGGLLT
                     NYKTISKRIKRISEIEKMEEDGLFEVLPKKEVVELKKEYDRLIKFLGGIRDMKSMPQA
                     LFVVDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMA
                     DAILEGQQGVSNEEVAAEQNIDLDEKEKSEETEATEE"
     gene            9868..9981
                     /locus_tag="RPH49_000807"
     CDS             9868..9981
                     /locus_tag="RPH49_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5123993.1"
                     /translation="MGDKILMLITFFKKKIEANYKYSIRVLAILPIIMLKS"
     gene            10016..10897
                     /locus_tag="RPH49_000808"
     CDS             10016..10897
                     /locus_tag="RPH49_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDY5123994.1"
                     /translation="MATISAKLVKELREKTGAGMMDCKKALTETDGDIDKAIDYLREK
                     GIAKAAKKADRIAAEGLVHVETKGNDAVIVEINSETDFVARNEGFQELVKEIANQVLD
                     TKAETVEALMETTLPNGKSVDERIKEAISTIGEKLSVRRFAIRTKTDNDAFGAYLHMG
                     GRIGVLTVVEGSTDEEAARDVAMHIAAINPKYVSSEQVSEEEINHEREVLKQQALNEG
                     KPENIVEKMVEGRLRKYLQEICAVDQDFVKNPDVTVEAFLKTKGGKLVDFVRYEVGEG
                     MEKREENFADEVKGQMK"
     gene            11034..11756
                     /locus_tag="RPH49_000809"
     CDS             11034..11756
                     /locus_tag="RPH49_000809"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDY5123995.1"
                     /translation="MAQISKYKRVVLKLSGEALAGEKGFGINPVIIKSVAEQVAEVAK
                     MDCEIAVIVGGGNIWRGKTGSDLGMDRGTADYMGMLATVMNALALQDSLEQLDCDTRV
                     LTSIEMKQVAEPYIRRRAIRHLEKKRVVIFAAGIGNPYFSTDTTAALRAAEVEADVIL
                     MGKNNVDGVYSADPKVNKDAVKYEHLTHIQMLQEGLQVMDSTASSFCMDNNIPLTVFS
                     IMEEGNIKRAVMGEKIGTLITK"
     gene            11775..12329
                     /gene="frr"
                     /locus_tag="RPH49_000810"
     CDS             11775..12329
                     /gene="frr"
                     /locus_tag="RPH49_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDY5123996.1"
                     /translation="MSDIINETKSRMQKSIESLSRELANISAGRANSNLLNGVTVDYY
                     GAPTPVQQLASINVPEARLLVISPYDKTSVADIEKAIIAANLGVNPTSDGEVIRIAVP
                     ALTEERRKERVKDVKKIGEEAKVSVRNIRRDMNDQLKKDEKNGDITEDELRSGTEDVQ
                     KATDNSIKEIDQMIADKEKDIMSV"
     gene            12702..13472
                     /locus_tag="RPH49_000811"
     CDS             12702..13472
                     /locus_tag="RPH49_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDY5123997.1"
                     /translation="MFKKLINKKNTINNYNEELDSSNIPEHIAIIMDGNGRWAKKRKM
                     PRIKGHYEGMQTIKKITRIASDIGVKYLTLYAFSTENWSRPESEVNYIMNLPVNFLKT
                     FLPELIEKNVKVETIGFTDKLPKSTIEAINNAKEKTANNTGLKLIFAINYGGRAELVH
                     SIKNMFDELHQQGLNSDIIDETYINNHLMTKDYPDPELLIRTSGEQRISNFLIWQVSY
                     SEFIFNQKLWPDFDEDELIKCIKIYQSRQRRFGGLSEE"
     gene            13479..14261
                     /locus_tag="RPH49_000812"
     CDS             13479..14261
                     /locus_tag="RPH49_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDY5123998.1"
                     /translation="MKVRTLTAIIALIVFLPILLKGGLVLMIFANILALIALKELLNM
                     NMIKFVSVPGLISAVGLIIIMLPQHAGPWVQVIQLKSLIAMSFIVLSYTVLSKNRFSF
                     MDAAFCLMSVAYVGIGFMFFYETRSEGLHYILYAFLIVWLTDTGAYLFGKMMGKHKLW
                     PVISPNKTIEGFIGGLFCSLIVPLAMLYFVDFNMNVWILLGVTLILSLFGQLGDLVES
                     GFKRHFGVKDSGRILPGHGGILDRFDSFMFVLPLLNILLIQA"
     gene            14473..15759
                     /gene="rseP"
                     /locus_tag="RPH49_000813"
     CDS             14473..15759
                     /gene="rseP"
                     /locus_tag="RPH49_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000121122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDY5123999.1"
                     /translation="MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMG
                     PKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILD
                     DHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
                     RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGL
                     QKGDKIVQIGKYKISEFDDVDKALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTK
                     VSSETKYVLGFQPASEHTLFKPIVFGFKSFLIGSTYIFTAVVGMLASIFTGGFSFDML
                     NGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFR
                     KPVNKKAETTIIAIGAIFMVVIMILVTWNDIRRYFL"
     gene            15779..17482
                     /locus_tag="RPH49_000814"
     CDS             15779..17482
                     /locus_tag="RPH49_000814"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDY5124000.1"
                     /translation="MKQSKVFIPTMRDVPSEAEAQSHRLLLKSGLIKQSTSGIYSYLP
                     LATRVLNNITAIVRQEMERIDSVEILMPALQQAELWEESGRWGAYGPELMRLQDRHGR
                     QFALGPTHEELVTSIVRNELKSYKQLPMTLFQIQSKFRDEKRPRFGLLRGREFIMKDA
                     YSFHADEASLDQTYQDMYQAYSRIFERVGINARPVVADSGAIGGSHTHEFMALSAIGE
                     DTIVYSKESDYAANIEKAEVVYEPNHKHTTVQPIEKIETPNVKTAQELADFLGRPVDE
                     IVKTMIFKVDGEYIMVLVRGHHEINDIKLKSYFGTDNIELATQDEIVNLVGANPGSLG
                     PVIDKEIKIYADNFVQDLNNLVVGANEDGYHLINVNVGRDFNVDAYGDFRFILEGEKL
                     SDGSGVAHFAEGIEVGQVFKLGTKYSESMNATFLDNQGKAQPLIMGCYGIGISRTLSA
                     IVEQNHDDNGIVWPKSVTPFDLHLISINPKKDDQRELADALYAEFNTKFDVLYDDRQE
                     RAGVKFNDADLIGLPLRIVVGKRASEGIVEVKERLTGDSEEVHIDDLITVITNKYDNL
                     K"
     gene            17746..22056
                     /locus_tag="RPH49_000815"
     CDS             17746..22056
                     /locus_tag="RPH49_000815"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDY5124001.1"
                     /translation="MTEQQKFKVLADQIKISNQLDAEILNSGELTRIDVSNKNRTWEF
                     HITLPQFLAHEDYLLFINAIEQEFKDIANVTCRFTVTNGTNQDEHVIKYFGHCIDQTA
                     LSPKVKGQLKQKKLIMSGKVLKVMVSNDIERNHFDKACNGSLIKAFRNCGFDIDKIIF
                     ETNDNDQEQNLASLEAHIQEEDEQSARLATEKLEKMKAEKAKQQDNNESAVDKCQIGK
                     PIQIENIKPIESIIEEEYKVAIEGVIFDINLKELKSGRHIVEIKVTDYTDSLVLKMFT
                     RKNKDDLEHFKALSVGKWVRAQGRIEEDTFIRDLVMMMSDIEEIKKATKKDKAEEKRV
                     EFHLHTAMSQMDGIPNISAYVKQAADWGHPAIAVTDHNVVQAFPDAHAAAEKHGIKMI
                     YGMEGMLVDDGVPIAYKPQDVVLKDATYVVFDVETTGLSNQYDKIIELAAVKVHNGEI
                     IDKFERFSNPHERLSETIINLTHITDDMLVDAPEIEEVLTEFKEWVGDAIFVAHNASF
                     DMGFIDTGYERLGFGPSTNGVIDTLELSRTINTEYGKHGLNFLAKKYGVELTQHHRAI
                     YDTEATAYIFIKMVQQMKELGVLNHNEINKKLSNEDAYKRARPSHVTLIVQNQQGLKN
                     LFKIVSASLVKYFYRTPRIPRSLLDEYREGLLVGTACDEGELFTAVMQKDQSQVEKIA
                     KYYDFIEIQPPALYQDLIDRELIRDTETLHEIYQRLIHAGDTAGIPVIATGNAHYLFE
                     HDGIARKILIASQPGNPLNRSTLPEAHFRTTDEMLNEFHFLGEEKAHEIVVKNTNELA
                     DRIERVVPIKDELYTPRMEGANEEIRELSYANARKLYGEDLPQIVIDRLEKELKSIIG
                     NGFAVIYLISQRLVKKSLDDGYLVGSRGSVGSSFVATMTEITEVNPLPPHYICPNCKR
                     SEFFNDGSVGSGFDLPDKTCETCGAPLIKEGQDIPFETFLGFKGDKVPDIDLNFSGEY
                     QPNAHNYTKVLFGEDKVFRAGTIGTVAEKTAFGYVKGYLNDQGIHKRGAEIDRLVKGC
                     TGVKRTTGQHPGGIIVVPDYMDIYDFTPIQYPADDQNSAWMTTHFDFHSIHDNVLKLD
                     ILGHDDPTMIRMLQDLSGIDPKTIPVDDKEVMQIFSTPESLGVTENEILCKTGTFGVP
                     EFGTGFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIKTGICDLSSVIGCRD
                     DIMVYLMYAGLEPSMAFKIMESVRKGKGLTEEMIETMKENEVPDWYLDSCLKIKYMFP
                     KAHAAAYVLMAVRIAYFKVHHPLYYYASYFTIRASDFDLITMIKDKTSIRNTVKDMYS
                     RYMDLGKKEKDVLTVLEIMNEMAHRGYRMQPISLEKSQAFEFIIEGDTLIPPFISVPG
                     LGENVAKRIVEARDDGPFLSKEDLNKKAGLSQKIIEYLDELGSLPNLPDKAQLSIFDM
                     "
     gene            22344..22811
                     /gene="rimP"
                     /locus_tag="RPH49_000816"
     CDS             22344..22811
                     /gene="rimP"
                     /locus_tag="RPH49_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDY5124002.1"
                     /translation="MSKITEQVEVIVQPIMEDLNFELVDVEYVKEGRDHFLRISIDKE
                     GGVDLNDCTLASEKISEAMDANDPIPEMYYLDVASPGAERPIKKEQDFQNAITKPVFV
                     SLYVPIEGEKEWLGILQEVNNETIVVQVKIKARTKDIEIPRDKIAKARHAVMI"
     gene            22832..24007
                     /gene="nusA"
                     /locus_tag="RPH49_000817"
     CDS             22832..24007
                     /gene="nusA"
                     /locus_tag="RPH49_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDY5124003.1"
                     /translation="MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSAR
                     NVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLSTALVKNPAYEIGDIYEEDVTPKD
                     FGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEA
                     VLSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYD
                     GTVIVKSVAREAGDRSKISVFSENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQW
                     NEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGKRGQNARLAAKLTGW
                     KIDIKSETDAREAGIYPVVEAEKVTEEDIALEDADTTESTEEVNDVSVETNVEKESE"
     gene            24028..24312
                     /locus_tag="RPH49_000818"
     CDS             24028..24312
                     /locus_tag="RPH49_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDY5124004.1"
                     /translation="MKKKKIPMRKCILSNEMHPKKDMIRVVVNKEGEIFADVTGKKQG
                     RGAYVSKDVAMVEKAQQKEILEKYFKASKEQLDPVYKEIIRLIYREEIPK"
     gene            24309..24626
                     /locus_tag="RPH49_000819"
     CDS             24309..24626
                     /locus_tag="RPH49_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ family RNA-binding protein"
                     /protein_id="HDY5124005.1"
                     /translation="MSIDQILNFLGLAMRAGKVKTGESVIVNEIKKGNLKLVIVANDA
                     SDNTAKLITDKCKSYKVPFRKFGNRNELGIALGKGERVNVGITDPGFAKKLLSMIDEY
                     HKE"
     gene            24631..26748
                     /gene="infB"
                     /locus_tag="RPH49_000820"
     CDS             24631..26748
                     /gene="infB"
                     /locus_tag="RPH49_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDY5124006.1"
                     /translation="MSKQRIYEYAKELNLKSKEIIDELKSMNIEVSNHMQALEDDQIK
                     ALDKKFKKEQKNDNKQSTQNNHQKSNNQNQNKGQQKDNKKNQQQNNKGNKGNKKNNRN
                     NKKNNKNNKPQNQPAAPKEIPSKVTYQEGITVGEFADKLNVESSEIIKKLFLLGIVAN
                     INQSLNQETIELIADDYGVEVEEEVVINEEDLSIYFEDEKDDPEAIERPAVVTIMGHV
                     DHGKTTLLDSIRHTKVTAGEAGGITQHIGAYQIENDGKKITFLDTPGHAAFTTMRARG
                     AQVTDITILVVAADDGVMPQTIEAINHAKEAEVPIIVAVNKIDKPTSNPDRVMQELTE
                     YGLIPEDWGGETIFVPLSALSGDGIDDLLEMIGLVAEVQELKANPKNRAVGTVIEAEL
                     DKSRGPSASLLVQNGTLNVGDAIVVGNTYGRIRAMVNDLGQRIKTAGPSTPVEITGIN
                     DVPQAGDRFVVFSDEKQARRIGESRHEASIVQQRQESKNVSLDNLFEQMKQGEMKDLN
                     VIIKGDVQGSVEALAASLMKIDVEGVNVRIIHTAVGAINESDVTLANASNGIIIGFNV
                     RPDSGAKRAAEAENVDMRLHRVIYNVIEEIESAMKGLLDPEFEEQVIGQAEVRQTFKV
                     SKVGTIAGCYVTEGKITRNAGVRIIRDGIVQYEGELDTLKRFKDDAKEVAKGYECGIT
                     IENYNDLKEGDVIEAFEMVEIKR"
     gene            27134..27484
                     /gene="rbfA"
                     /locus_tag="RPH49_000821"
     CDS             27134..27484
                     /gene="rbfA"
                     /locus_tag="RPH49_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDY5124007.1"
                     /translation="MSSMRAERVGEQMKKELMDIINNKVKDPRVGFITITDVVLTNDL
                     SQAKVFLTVLGNDKEVENTFKALDKAKGFIKSELGSRMRLRIMPELMYEYDQSIEYGN
                     KIERMIQDLHKQDR"
     gene            27653..28570
                     /gene="truB"
                     /locus_tag="RPH49_000822"
     CDS             27653..28570
                     /gene="truB"
                     /locus_tag="RPH49_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDY5124008.1"
                     /translation="MYNGILPVYKERGLTSHDVVFKLRKILKTKKIGHTGTLDPEVAG
                     VLPVCIGNATRVSDYVMDMGKAYEATVSIGRSTTTEDQTGDTLETKGVHSADFNKDDI
                     DRLLESFKGIIEQIPPMYSSVKVNGRKLYEYARNNETVERPKRKVNIKDIGRISELDF
                     KENECHFKIRVICGKGTYIRTLATDIGVKLGFPAHMSKLTRIESGGFVLKDSLTLEQI
                     KELHEQDSLQNKLFPLEYGLKGLPSIKIKDSHIKKRILNGQKFNKNEFDNKIKDQIVF
                     IDDDSEKVLAIYMVHPTKESEIKPKKVFN"
     gene            28585..29556
                     /gene="ribF"
                     /locus_tag="RPH49_000823"
     CDS             28585..29556
                     /gene="ribF"
                     /locus_tag="RPH49_000823"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDY5124009.1"
                     /translation="MKVIEVTHPIQSKQYITEDVAMAFGFFDGMHKGHDKVFDILNEI
                     AEARSLKKAVMTFDPHPSVVLNPKRKRTTYLTPLSDKIEKISQHDIDYCIVVNFSSRF
                     ANVSVEDFVENYIIKNNVKEVIAGFDFTFGKFGKGNMTVLQEYDAFNTTIVSKQEIEN
                     EKISTTSIRQDLINGELQKANDALGYIYSIKGTVVQGEKRGRTIGFPTANIQPSDDYL
                     LPRKGVYAVSIEIGTENKLYRGVANIGVKPTFHDPNKAEVVIEVNIFDFEDNIYGERV
                     TVNWHHFLRPEIKFDGIDPLVKQMNDDKSRAKYLLAVDFGDEVAYNI"
     gene            29671..29940
                     /gene="rpsO"
                     /locus_tag="RPH49_000824"
     CDS             29671..29940
                     /gene="rpsO"
                     /locus_tag="RPH49_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDY5124010.1"
                     /translation="MAISQERKNEIIKEYRVHETDTGSPEVQIAVLTAEINAVNEHLR
                     THKKDHHSRRGLLKMVGRRRHLLNYLRSKDIQRYRELIKSLGIRR"
     gene            30310..32406
                     /gene="pnp"
                     /locus_tag="RPH49_000825"
     CDS             30310..32406
                     /gene="pnp"
                     /locus_tag="RPH49_000825"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDY5124011.1"
                     /translation="MSQEKKVFKTEWAGRSLTIETGQLAKQANGAVLVRYGDTVVLST
                     ATASKEPRDGDFFPLTVNYEEKMYAAGKIPGGFKKREGRPGDDATLTARLIDRPIRPL
                     FPKGYKHDVQIMNMVLSADPDCSPQMAAMIGSSMALSVSDIPFQGPIAGVNVGYIDGK
                     YIINPTVEEKEVSRLDLEVAGHKDAVNMVEAGASEITEQEMLEAIFFGHEEIQRLVEF
                     QQQIVDHIQPVKQEFIPAERDEALVERVKSLTEEKGLKETVLTFDKQQRDENLDNLKE
                     EIVNEFIDEEDPENELLIKEVYAILNELVKEEVRRLIADEKIRPDGRKPDEIRPLDSE
                     VGILPRTHGSGLFTRGQTQALSVLTLGALGDYQLIDGLGPEEEKRFMHHYNFPNFSVG
                     ETGPVRAPGRREIGHGALGERALKYIIPDTADFPYTIRIVSEVLESNGSSSQASICGS
                     TLALMDAGVPIKAPVAGIAMGLVTREDSYTILTDIQGMEDALGDMDFKVAGTKEGITA
                     IQMDIKIDGLTREIIEEALEQARRGRLEIMNHMLQTIDQPRTELSAYAPKVVTMTIKP
                     DKIRDVIGPGGKKINEIIDETGVKLDIEQDGTIFIGAVDQAMINRAREIIEEITREAE
                     VGQTYQATVKRIEKYGAFVGLFPGKDALLHISQISKNRIEKVEDVLKIGDTIEVKITE
                     IDKQGRVNASHRALEE"
     gene            32642..34315
                     /locus_tag="RPH49_000826"
     CDS             32642..34315
                     /locus_tag="RPH49_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002455407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDY5124012.1"
                     /translation="MSLIKKKNKDIRIIPLGGVGEIAKNMYIVEVDDEMFMLDAGLMF
                     PEDEMLGIDIVIPDISYVLENKDKLKGIFLTHGHEHAIGAVSYVLEQLDAPVYGSKLT
                     IALIKENMKARNIDKKVRYYTVNNDSIMRFKNVNISFFNTTHSIPDSLGVCIHTSYGA
                     IVYTGEFKFDQSLHGHYAPDIKRMAEIGEEGVFVLISDSTEAEKPGYNTPENVIEHHM
                     YDAFAKVRGRLIVSCYASNFIRIQQVLNIASKLNRKVSFLGRSLESSFNIARKMGYFD
                     IPKDLLIPITEVDNYPKNEVIIIATGMQGEPVEALSQMAQHKHKIMNIEEGDSVFLAI
                     TASANMEVIIANTLNELVRAGAHIIPNNKKIHASSHGCMEELKMMINIMKPEYFIPVQ
                     GEFKMQIAHAKLAAEAGVAPEKIFLVEKGDVINYNGKDMILNEKVNSGNILIDGIGIG
                     DVGNIVLRDRHLLAEDGIFIAVVTLDPKNRRIAAGPEIQSRGFVYVRESEDLLREAEE
                     KVREIVEAGLQEKRIEWSEIKQNMRDQISKLLFESTKRRPMIIPVISEI"
     gene            34572..36941
                     /locus_tag="RPH49_000827"
     CDS             34572..36941
                     /locus_tag="RPH49_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDY5124013.1"
                     /translation="MAQAKKKSTAKKKTTSKKRTNSRKKKNDNPIRYVIAILVVVLMV
                     LGVFQLGIIGRLIDSFFNYLFGYSRYLTYILVLLATGFITYSKRIPKTRRTAGSIVLQ
                     IALLFVSQLVFHFNSGIKAEREPVLSYVYQSYQHSHFPNFGGGVLGFYLLELSVPLIS
                     LFGVCIITILLLCSSVILLTNHQHREVAKVVLENIKAWFGSFNEKMSEKNQEKQLKRE
                     EKARLKEEQKARQNEQPQIKDVSDFTEVPQERDIPIYGHTENESKSQSQPSRKKRVFD
                     AENSSNNIVNHHQADQQEQLTEQTHNSVESENTIEEAGEVTNVSYVVPPLTLLNQPAK
                     QKATSKAEVQRKGQVLENTLKDFGVNAKVTQIKIGPAVTQYEIQPAQGVKVSKIVNLH
                     NDIALALAAKDVRIEAPIPGRSAVGIEVPNEKISLVSLKEVLDEKFPSNNKLEVGLGR
                     DISGDPITVPLNEMPHLLVAGSTGSGKSVCINGIITSILLNAKPHEVKLMLIDPKMVE
                     LNVYNGIPHLLIPVVTNPHKAAQALEKIVAEMERRYDLFQHSSTRNIKGYNELIRKQN
                     QELDEKQPELPYIVVIVDELADLMMVAGKEVENAIQRITQMARAAGIHLIVATQRPSV
                     DVITGIIKNNIPSRIAFAVSSQTDSRTIIGTGGAEKLLGKGDMLYVGNGDSSQTRIQG
                     AFLSDQEVQDVVNYVVEQQQANYVKEMEPDAPVDKSEMKSEDALYDEAYLFVVEQQKA
                     STSLLQRQFRIGYNRASRLMDDLERNQVIGPQKGSKPRQVLIDLNNDEV"
     gene            36946..37659
                     /locus_tag="RPH49_000828"
     CDS             36946..37659
                     /locus_tag="RPH49_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5124014.1"
                     /translation="MSEMNAVYNVKQYILNLIKQNKLEYGDQLPSNLSIARELNVKTD
                     DVYEAIQALITEQVIKDNFEEGTSVKSLPPFFYPLNELISIGQMIKNAGFECGTEYLN
                     FDEQPATMLDANLLSVEEGYPVTIIERLRTADGEPVVYCLDKIAKKELTCTEYQMSNG
                     SILSAIKEQSNHNICYADTEIEAVNYEPRISEVLNASPHEGLILLKITHYNESDEPIL
                     YSLNYMKNSLVQFKITRKI"
     gene            37690..38955
                     /locus_tag="RPH49_000829"
     CDS             37690..38955
                     /locus_tag="RPH49_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDY5124015.1"
                     /translation="MSRQSQPNIHIKVSPTTKFKTTTIVFKFMAPLEYDTITARSLLS
                     KLLVRATKKWPTDKSFNNHLADLYGAYVNSTISKFKDQHVITFSLEIVNERYLRNGES
                     LFNQGLDLLHEIIWNPLIENKAFNDNFVNQEKTLLAKKIEAMVDNKAQYSFLKLLDHM
                     FENEAYKYLSTGQLEQIPHITAETLYHTYQSMINNDQCSVYVVGNVEPESVEKQIREK
                     FALKPFDKHQFQHSTHHLHDEEVDYIVEYDDVDQAKLNMGYRFPTQYGQSGYAAFVVF
                     NMMFGGDPSSVLFNEVREKQSLAYSIHSQIDGKNGYLFVLSGVSSDKYETAKDTIISE
                     FEKIKAGDFTEEKLELAKKVIISHRYESEDRPKSIIEIMHNQILLEQPQSKETFINDI
                     QKVSREDIVTVAEKAFLDTIYVLTKGGDK"
     gene            38955..40241
                     /locus_tag="RPH49_000830"
     CDS             38955..40241
                     /locus_tag="RPH49_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDY5124016.1"
                     /translation="MKERYYELIDERVFEQELENGLRLFIIPKPGFQKTFVTYTTQFG
                     SLDNQFKPLGQDQFVTVPDGVAHFLEHKLFEKEEEDLFTAFAEDNAQANAFTSFDRTS
                     YLFSATDNIENNIKRLLTMVETPYFTKETVDKEKGIIAEEIKMYQEQPGYKLMFNTLR
                     AMYQQHPIRVDIAGSVESIYDITKDDLYLCYETFYHPSNMVLFVVGDVNPEEICRIVK
                     QHEDARNKVNQPKIERGLVDEPEDVKEAFVTESMKIQSPRLMLGFKNKPLQEAPQKYV
                     QRDLEMSLFFELIFGEETDFYQNLLNEGLIDDTFGYQFVLEPTYSFSIVTSATEEPDK
                     LKKLLLDELRDKKGNFQDAQAFELLKKQFIGEFISSLNSPEYIANQYTKLYFEGVSVF
                     DMLDIVENITLDSINETSSLYLNLDQQVDSRLEIKK"
     gene            40241..40945
                     /locus_tag="RPH49_000831"
     CDS             40241..40945
                     /locus_tag="RPH49_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDY5124017.1"
                     /translation="MKALVLGGSGSIGSEIVKQLLTDGFEVYVQYYRTDINELTSKFN
                     DDKVHFIQTDLSQTTDIDKTFGDIKSLDCLIYASGQSLYGVLQDMKDHDIDACYQLNV
                     LQLIRLCRYFVDVLRQSDNGRIIVISSIWGETGASMETIYSTMKSAQLGFVKALSQEL
                     ALTSVTVNAIAPGFVAGNMASEWQEDELQAMITELPQQRLVLPSEVAHTCAYLYHPNA
                     RSVTGTIQKVNGAWYI"
     gene            41050..41877
                     /locus_tag="RPH49_000832"
     CDS             41050..41877
                     /locus_tag="RPH49_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfK family protein"
                     /protein_id="HDY5124018.1"
                     /translation="MTVAEKKEWYLEYEIEINRPGLLGDVSSLLGMLGISIVTINGVD
                     QGKRGLLIKTDNLEKVERFEQIARGINEIEITKLKKPELRDRLAVRHGRYIEQDAKDK
                     KTFRFEREDLGLLVDFLAELFKEEGHKLIGIRGMPRVGKTESIVAGSVCAHKRWLFIS
                     STLIKQTVRSSLIKGEYDANHVYIIDGAVTARESNPKHQELVNEVMTLPSIKVVEHPD
                     LFVETSTCTMEDFDYIIELRENENQEIHYEEMKKQTVQSKNNLDFGDPFGGGFGFFE"
     gene            41896..42288
                     /locus_tag="RPH49_000833"
     CDS             41896..42288
                     /locus_tag="RPH49_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5124019.1"
                     /translation="MKTVGEALKGRRERLGMTLTELEQRTGIKREMLVHIENNEFDQL
                     PNKNYSEGFIRKYASVVNIEPNQLIQAHQDEIPSNQAEWDEVITVFNNNKDLDYKSKS
                     KEPIQLLVIMGITVLITLLLWIMLVLIF"
     gene            42322..42900
                     /gene="pgsA"
                     /locus_tag="RPH49_000834"
     CDS             42322..42900
                     /gene="pgsA"
                     /locus_tag="RPH49_000834"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDY5124020.1"
                     /translation="MNIPNQITVFRVVLIPVFILFALVDFGFGNVSFLGGYEIRIELL
                     ISGFIFILASLSDFVDGYLARKWNLVTNMGKFLDPLADKLLVASALIVLVQLGLTNSV
                     VAIIIIAREFAVTGLRLLQIEQGFVSAAGQLGKIKTAVTMVAITWLLLGDPLATLIGL
                     SLGQILLYIGVIFTILSGIEYFYKGRDVFKQK"
     gene            43125..44276
                     /locus_tag="RPH49_000835"
     CDS             43125..44276
                     /locus_tag="RPH49_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CinA family nicotinamide mononucleotide
                     deamidase-related protein"
                     /protein_id="HDY5124021.1"
                     /translation="MSIAIIAVGSELLLGQIANTNGQFLSKVFNEIGQNVLEHKVIGD
                     NKKRLESSVRHALEKYDTVILTGGLGPTKDDLTKHTVAQIVGKDLVIDEPSLKYIESY
                     FEEQGQEMTPNNKQQALVIEGSTVLANHHGMAPGMMVNFENKQIILLPGPPKEMQPMV
                     KNELLSHFINHNRIIHSELLRFAGIGESKVETILIDLIDKQTNPTIAPLAGSHEVYIR
                     LTANADSKEQAQSLIQPVKQEILDRIGEYYYGSDDTLIEQAVIKKIHEPFVIYDGITN
                     GALYHRLKEVDLNDVLKGMINHNENFVDINKPIEQQLKDAVQFVNKLFNVSSAIILLE
                     YDGVVHIGYDNNFEFKTEQFKMSKSRNLLKNRSQNYALIRLLNWLRTTN"
     gene            44441..45484
                     /gene="recA"
                     /locus_tag="RPH49_000836"
     CDS             44441..45484
                     /gene="recA"
                     /locus_tag="RPH49_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDY5124022.1"
                     /translation="MDNDRQKALDTVIKNMEKSFGKGAVMKLGDNIGRRVSTTSTGSV
                     TLDNALGVGGYPKGRIIEIYGPESSGKTTVALHAIAEVQSNGGVAAFIDAEHALDPEY
                     AQALGVDIDNLYLSQPDHGEQGLEIAEAFVRSGAVDIVVVDSVAALTPKAEIEGEMGD
                     THVGLQARLMSQALRKLSGAISKSNTTAIFINQIREKVGVMFGNPETTPGGRALKFYS
                     SVRLEVRRAEQLKQGQEIVGNRTKIKVVKNKVAPPFRVAEVDIMYGQGISKEGELIDL
                     GVENDIVDKSGAWYSYNGERMGQGKENVKMYLKENPQIKEEIDRKLREKLGISDGDVE
                     ETEDTPKSLFDEE"
     gene            45838..47397
                     /gene="rny"
                     /locus_tag="RPH49_000837"
     CDS             45838..47397
                     /gene="rny"
                     /locus_tag="RPH49_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002459258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDY5124023.1"
                     /translation="MNLLSLLLILLGIILGVVGGYVVARNLLLQKQSQARQTAEDIVN
                     QAHKEADNIKKEKLLEAKEENQILREQTEAELRERRSELQRQETRLLQKEENLERKSD
                     LLDKKDEILEQKESKIEEKQQQVDAKESSVQTLIMKHEQELERISGLTQEEAINEQLQ
                     RVEEELSQDIAVLVKEKEKEAKEKVDKTAKELLATAVQRLAADHTSESTVSVVNLPND
                     EMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVILSGFDPIRREIARTALVNLVSDG
                     RIHPGRIEDMVEKARKEVDDIIREAGEQATFEVNAHNMHPDLVKIVGRLNYRTSYGQN
                     VLKHSIEVAHLASMLAAELGEDETLAKRAGLLHDVGKAIDHEVEGSHVEIGVELAKKY
                     GENETVINAIHSHHGDVEPTSIISILVAAADALSAARPGARKETLENYIRRLERLETL
                     SESYDGVEKAFAIQAGREIRVIVSPEEIDDLKSYRLARDIKNQIEDELQYPGHIKVTV
                     VRETRAVEYAK"
     gene            complement(47651..48654)
                     /locus_tag="RPH49_000838"
                     /pseudo
     CDS             complement(47651..48654)
                     /locus_tag="RPH49_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        17909 a         6647 c         9391 g        14707 t
ORIGIN      
        1 caaaaaggag ttgatttatt gattagacta tttttgctta agttatactg gtcacacttt
       61 tcgactaaac aaattcatca atttttaatg gcatatccta atgtaattaa agaggaggga
      121 agaaaaaaag atagttattt atgtgaatgg gtgaataggg aagaaaatgt tcatttatta
      181 cgtaaatact atgcttttat aaaacttgat cataacgata ttattaaaga actgcagaaa
      241 ttaaaagtaa gttacattac atatatggat tctgaatacc cagtgctatt aaaagaaata
      301 tatcaatttc cattacttct tttctataaa gggaacatca aattaataaa taatatgcat
      361 catttggcag tagtaggtgc aagagattct acaagttata cccaacagtc tttagaattt
      421 ttattatcaa atgataaaag caaatattta acaattgttt ccggccttgc tcaaggagct
      481 gatgcaatgg cacatcaaat agctttaaaa tacaatctcc ctacaattgc agttttagcc
      541 tttggccatc aaacacatta tcccaaaagt acattagcat taagaaataa aatagaagaa
      601 aaaggtttag ttatatccga atatccacca catacaccaa ttgctaaata tagatttcct
      661 gagcgcaata gaattatcag cggtttgtca aaaggggttt taattactga ggctaaggaa
      721 caaagtggca gtcacatcac gatagatttt gcattagagc aaaatagaaa tgtttatgtt
      781 ttacctggat ctatgtttaa tcctatgaca aaaggtaatt tattacgtat ccaagaaggt
      841 gctaaggtag tattaaacgc taatgatata tttgaagact actatattta aaactaaaaa
      901 taacgagttg cttcatattt cttttgttac cctttgtaat ttatttttta ataaaatcta
      961 taaaaaatag acagggaaaa tgatttgttt agatataaaa cgttgacaaa agcaaaatta
     1021 agcgtttatc atttatcttt agtaattaga ttagcgaggg ggaaatgaca ttggcagata
     1081 atttagtcat tgttgaatcg cctgcaaaag caaaaaccat tgaaaagtat ttaggtaaga
     1141 aatataaagt tatagcttca atgggacacg tcagagactt accaagaagt caaatgggtg
     1201 tcgacactga agataattac gaaccaaaat atataacaat acgcggaaaa ggtcctgttg
     1261 taaaagaatt gaaaaagcat gcaaaaaaag cgaaaaacgt ctttctcgca agtgaccccg
     1321 accgtgaagg tgaagcaatt gcttggcatt tatcaaaaat tttagagctt gaagattcta
     1381 aagaaaatcg cgttgttttc aacgaaataa ctaaagacgc tgttaaagaa agttttaaaa
     1441 atcctagaga aattgaaatg aacttagtcg atgcacaaca agcgcgtcga atattagata
     1501 gattggttgg ctataacatc tcgccagttc tatggaaaaa agtaaaaaaa gggttgtcag
     1561 cgggtcgagt tcaatctgtt gcacttcgtt tagtcattga ccgtgaaaat gaaattcgaa
     1621 actttaaacc agaagaatat tggactattg aaggagaatt tagatacaaa aaatcaaaat
     1681 tcaatgctaa attccttcat tataaaaata aaccttttaa attaaaaacg aaaaaagatg
     1741 ttgagaaaat tacagctgca ttagatggag atcaattcga aattacaaac gtgactaaaa
     1801 aagaaaaaac gcgtaatcca gcaaacccat ttacaacttc tacattacaa caagaggcgg
     1861 cacgtaaatt aaactttaaa gctagaaaaa caatgatggt cgcacaacaa ttatatgaag
     1921 gtatagattt gaaaaaacaa ggtacgattg gtttaataac atatatgaga accgattcta
     1981 cacgtatttc agatactgcc aaagctgaag caaaacagta tataactgat aaatacggtg
     2041 aatcttacac ttctaaacgt aaagcatcag ggaaacaagg tgaccaagat gcccatgagg
     2101 ctattagacc ttcaagtact atgcgtacgc cagatgatat gaagtcattt ttaacgaaag
     2161 accaataccg attatacaaa ttaatttggg aacgatttgt tgctagtcaa atggctccag
     2221 caatacttga tacagtctca ttagacataa cacaaggtga cattaaattt agagcgaatg
     2281 gtcaaacaat caagtttaaa ggatttatga cactctatgt agaaactaaa gatgatagtg
     2341 atagcgaaaa ggaaaataaa ctgcctaaat tagagcaagg tgataaagtc acagcaactc
     2401 aaattgaacc agctcaacac tatacacaac cacctccaag atatactgag gcgagattag
     2461 taaaaacact tgaagaattg aaaattgggc gaccatcaac atatgcaccg acaatagata
     2521 cgattcaaaa gcgtaactat gtcaaattag aaagtaagcg ttttgttcct actgagttgg
     2581 gagaaatagt tcatgaacaa gtgaaagaat acttcccaga gattattgat gtggaattca
     2641 cagtgaatat ggaaacgtta cttgataaga ttgcagaagg cgacattaca tggagaaaag
     2701 taatcgacgg tttctttagt agctttaaac aagatgttga acgtgctgaa gaagagatgg
     2761 aaaagattga aatcaaagat gagccagccg gtgaagactg tgaagtttgt ggttctccta
     2821 tggttataaa aatgggacgc tatggtaagt tcatggcttg ctcaaacttc ccggattgtc
     2881 gtaatacaaa agcgatagtt aagtctattg gtgttaaatg tccaaaatgt aatgatggtg
     2941 acgtcgtaga aagaaaatct aaaaagaatc gtgtctttta tggatgttcg aaatatcctg
     3001 aatgcgactt tatctcttgg gataagccga ttggaagaga ttgtccaaaa tgtaaccaat
     3061 atcttgttga aaataaaaaa ggcaagacaa cacaagtaat atgttcaaat tgcgattata
     3121 aagaggcagc gcagaaataa tatttttatt tcctagagac aatttaagaa tgttaaatag
     3181 aatcattagt gaatcttatt ttaaagatag taatggatta atctaaataa gtgcggataa
     3241 tataaacata acaacataat taaaagacat aaatgacaat aaaaggagta tagaaatgac
     3301 tcaaactgta aatgtaatag gtgctggtct tgccggttca gaagcggcat atcaattagc
     3361 tgaaagagga attaaagtta atctaataga gatgagacct gttaaacaaa caccagcgca
     3421 ccatactgat aaatttgcgg aacttgtatg ttccaattca ttacgcggaa atgctttaac
     3481 taatggtgtg ggtgttttaa aagaagaaat gagaagattg aattctataa ttattgaagc
     3541 ggctgataag gcacgagttc cagctggtgg tgcattagca gttgatagac acgatttttc
     3601 aggttatatt actgaaacac tcaaaaatca tgaaaatatc acagttatta atgaagaaat
     3661 taatgccatt ccagatggat acacaattat cgcaacagga ccacttacta cagaaacgct
     3721 tgctcaagaa atagtggaca ttactggtaa agatcaactt tatttctatg atgcagctgc
     3781 tccaattatt gaaaaagaat ctattgatat ggataaagtt tacttaaagt cccgttatga
     3841 taaaggtgaa gctgcatatt taaactgtcc tatgactgag gatgaattta atcgttttta
     3901 tgatgcagta ttagaagctg aagttgcgcc tgtaaattca tttgaaaaag aaaaatattt
     3961 cgagggttgt atgccttttg aagtaatggc agaacgcgga cgcaagacat tactatttgg
     4021 accaatgaaa ccagtaggat tagaagatcc aaagactggg aaacgtcctt atgcagtggt
     4081 tcaattaaga caagatgacg ctgctggcac actctacaat attgtcggct tccaaacgca
     4141 tttaaaatgg ggagctcaaa aagaagttat taaattaatt ccaggcttag aaaatgttga
     4201 tattgttaga tatggtgtga tgcatagaaa taccttcatt aactcaccgg acgtattaaa
     4261 cgagaaatat gaattgattt cacaaccaaa catacagttt gcgggacaaa tgactggtgt
     4321 tgaaggttat gtggaaagcg cagctagtgg cttagttgca ggcatcaatc ttgcgcataa
     4381 aatattaggc aaaggtgagg tagtatttcc gagagaaact atgattggaa gtatggctta
     4441 ctatatttct catgctaaaa acaataagaa tttccaacct atgaatgcta actttgggtt
     4501 attaccatct ttagaaacta gaattaaaga taaaaaagaa cgctatgaag cacaagctaa
     4561 tagagctttg gattacttag aaaatttcaa aaaaacttta taaaatagtt agaaagacta
     4621 gatatgctat tcattcttaa gtcatcaacg agtaagtaat gactttctaa atggaaaata
     4681 cttatcctag tctttttaat tttggaattg ttacgtattt ctgacaattg agaattcgca
     4741 ttcaaaaaat atctaaataa ataacacgca ataagttgat tgatgtaaca tgtaagagaa
     4801 tgttttaaat aaactttatt taaaagacaa tgaaataata aatggcaagg ctattaataa
     4861 agacttttag taattaattt aaaaaagagg tattctaatt aacaggtttt ccgattagtt
     4921 acaattattt aattctcaaa agatttagaa ttgattatca aattactgta agccctttgc
     4981 tgtatatgct acaattctta ttgatggagg gtaaatgtat tgaatcatat tcaagaagcg
     5041 tttttaaata cattgaaagt tgaacggaat ttttcggaac atacattgaa atcatatcaa
     5101 gatgacttaa ttcagtttaa tcaattttta gaacaagaac atttacagtt gaatactttt
     5161 gaatacagag atgctagaaa ttatttgagc tatttatatt caaatcattt gaaaagaaca
     5221 tctgtttctc gtaaaatctc aacgttaaga actttctatg aatattggat gacgcttgat
     5281 gagaacatta ttaatccatt tgttcaatta gtacatccga aaaaagaaaa atatcttccg
     5341 caattctttt acgaagaaga aatggaagcg ttatttaaaa ctgtagaaga ggacacttca
     5401 aaaagtttac gggatcgagt tattcttgaa ttgttatatg ctacaggtat ccgtgtttcg
     5461 gaattagtta atattaaaaa acaagatata gatttttacg cgaatggtgt taccgtgtta
     5521 ggaaaaggga gcaaagagcg ctttgtaccg tttggtgctt attgtagaca aagcatcgaa
     5581 aattatttag aacatttcaa acctattcag tcatgcaatc atgattttct tattgtaaat
     5641 atgaagggtg aagcaatcac tgaacgcggt gtacgatatg ttttaaatga tattgttaaa
     5701 cgaacagcag gcgtaagtga gattcatccc cacaagctca gacatacatt tgcaacgcat
     5761 ttattgaatc aaggtgcaga cctaagaaca gtacaatcat tattaggtca tgttaatttg
     5821 tcaacaactg gtaaatatac acacgtatct aaccaacaat taagaaaagt gtatctaaat
     5881 gcacatcctc gagcgaaaaa ggagaatgaa acatgagtaa tacaacatta catgcaacaa
     5941 caatttatgc tgtaagacat aatgggaaag cagctatggc tggagatggg caagtaacgc
     6001 ttggtcaaca agtcatcatg aaacaaacgg caagaaaagt gcgacgttta tatgaagata
     6061 aagtgttagc tggtttcgca ggtagtgtag cagatgcgtt tacgttattt gaaaaattcg
     6121 aaacaaaatt acaacagttt agtggtaact tagaaagagc tgctgttgaa ttggcacaag
     6181 aatggcgagg cgataaacaa ttacgtcaat tagaagctat gctaattgta atggataaag
     6241 atgctatttt agttgtcagt ggaactggcg aagttattgc cccagatgat gaccttatcg
     6301 ctattggatc aggaggcaac tacgcattaa gcgcaggacg tgcattgaaa cgccatgcat
     6361 cgcatttgtc tgctgaagaa atggcatatg agagcttgaa agtagcggct gatatttgtg
     6421 tctttaccaa cgataatatt gttgtcgaaa cactataata atcagagcac gataaataat
     6481 tacgagcaat taattttagt taaaagacgg aggaatgaaa ttaatggata cagctggaat
     6541 aagattaact ccaaaagaaa tcgtatctaa attaaatgaa tacatcgttg gacaaaatga
     6601 tgctaaacgt aaagtggcaa ttgccctacg taatcgatac agaagaagtt tattagatga
     6661 ggaatcaaag caagaaattt cacctaaaaa tattttgatg attggaccaa ccggcgttgg
     6721 taaaactgaa attgcaagaa gaatggccaa agttgtcggc gcaccattta taaaagtaga
     6781 agctactaaa tttactgagg taggttatgt aggacgagat gttgaaagta tggttagaga
     6841 tcttgttgat gtttcagtaa ggttagtcaa ggcgcagaaa aaatcattgg tacaagatga
     6901 agcaacagct aaggctaatg aaaaacttgt taagttatta gttccaagta tgaaaaagaa
     6961 agcatctcaa acgaataatc ctttagagtc acttttcgga ggtgcaattc caaatttcgg
     7021 acaaaataac gaagatgaag aagaaccacc tactgaggaa attaaaacaa aacgttctga
     7081 aattaagaga caattagaag aaggcaaact tgaaaaagaa aaggtaagaa ttaaagtcga
     7141 acaagatcct ggtgctttag gtatgctagg tacaaatcaa aatcagcaaa tgcaagagat
     7201 gatgaatcaa ttaatgccta aaaagaaagt tgagcgagaa gttgctgttg agacggcaag
     7261 gaaaatacta gctgatagtt atgcggatga actaattgat caagaaagcg ctaaccaaga
     7321 agcacttgaa ttagcagaac aaatgggtat catctttata gatgaaatcg acaaagttgc
     7381 gacgaataat cataatagtg gtcaagatgt ctcaagacaa ggtgttcaaa gagatatttt
     7441 acctatactt gaaggtagcg ttattcaaac caaatatggt actgtgaata ctgaacatat
     7501 gctgtttata ggtgctggag ctttccatgt atctaagccg agtgacttga taccagaatt
     7561 gcaaggtcgt tttccgatta gagttgaact tgatagttta tcggtagaag attttgtaag
     7621 aattttgaca gaaccaaaat tgtcattaat taaacaatat gaagcattgc ttcaaacaga
     7681 agaagttact gtaaacttta ccgatgaagc aattactcgc ttagctgaga ttgcctatca
     7741 agtaaatcaa gatacagaca atattggtgc acgtcgactt catacaattt tagaaaagat
     7801 gctagaagat ttatcattcg aagcaccaag tatgccgaat gcagttgtag atattacccc
     7861 acaatatgtt gatgataaat taaaatcaat ttcaacaaat aaagatttaa gtgcatttat
     7921 tctataaaaa tatacaaaag gagaaaaatt catgagctta ttatctaaaa cgagagagtt
     7981 aaacacgtta cttcaaaaac acaaaggtat tgcggttgat tttaaagatg tagcacaaac
     8041 gattagtagc gtaactgtaa caaatgtatt tattgtatcg cgtcgaggta aaattttagg
     8101 atcgagtcta aatgaattat taaaaagtca aagaattatt caaatgttgg aagaaagaca
     8161 tattccaagt gaatatacag aacgattaat ggaagttaaa caaacagaat caaatattga
     8221 tatcgacaat gtattaacag ttttcccacc tgaaaacaga gaattattca tagatagtcg
     8281 tacaactatc ttcccaattt taggtggagg agaaagatta ggtacattag tacttggtcg
     8341 agtacatgat gattttaatg aaaatgattt ggtactaggt gaatatgctg ctacagttat
     8401 tggtatggaa atcttacgtg agaagcatag tgaagtagaa aaagaagcgc gcgataaagc
     8461 tgctattaca atggcaatta attcattatc ttattctgaa aaagaagcaa ttgaacatat
     8521 ctttgaagaa cttggcggta cggaaggcct attaatcgca tcaaaagttg cagatagagt
     8581 tggtattact agatctgtaa ttgtaaatgc actacgtaaa ttagaaagtg ctggtgtaat
     8641 tgaatcacgt tctttaggaa tgaaaggtac tttcattaaa gttaaaaaag aaaaattctt
     8701 agatgaatta gaaaaaagta agtaaaacga tgagtctggg gcataattca atgtcctagt
     8761 cgtgacgatg ttatcttggc agtagtcaac gaaatgactt tgatgattat gttgaagtca
     8821 tttctttatt tttgtctaat tttcaatcaa attgatattc cacattaaca tgatagaatt
     8881 acctttaaat ttatgaaaaa atgcttgaaa aacatttgct ttagacacgg cattatgtta
     8941 tatttatttt cggctataaa gccaatacac acatatcaaa cgtgattgtg taaagggtgc
     9001 aatatttgta tattgtcttt acaatagttt gctatggagg taattaacca ataggaggaa
     9061 tttataatgg cagtaatttc aatgaaacaa ttactagaag cgggtgttca cttcggtcac
     9121 caaacacgtc gttggaaccc aaaaatgaaa aaatatatct tcactgagag aaatggtatt
     9181 tatatcatcg acttacaaaa aacagtgaaa aaagtagacg aggcatacaa cttcttgaaa
     9241 caagtttcag aagatggtgg acaagtctta ttcgtaggaa ctaaaaaaca agcacaagaa
     9301 tcagttaaat ctgaagcaga acgtgctggt caattctaca ttaaccaaag atggttaggt
     9361 ggattattaa ctaactataa aacgatctca aaacgaatca aacgtatttc tgaaattgaa
     9421 aaaatggaag aagatggttt attcgaagta ttacctaaaa aagaagtagt agaacttaaa
     9481 aaagaatatg accgtttaat caaattctta ggcggaattc gtgatatgaa atcaatgcct
     9541 caagcattat tcgtagttga cccacgtaaa gagcgtaatg caattgctga agctcgtaaa
     9601 ttaaatattc ctatcgtagg tatcgttgac actaactgtg atcctgacga aattgactac
     9661 gttatcccag caaacgacga tgctatccgt gcggttaaat tattaactgc taaaatggca
     9721 gatgcaatct tagaaggtca acaaggcgtt tctaatgaag aagtagctgc agaacaaaac
     9781 atcgatttag atgaaaaaga aaaatcagaa gaaacagaag caactgaaga ataatcaact
     9841 gttgaatctg acttagatat agtttaaatg ggtgataaga tattaatgct tatcaccttt
     9901 tttaaaaaga aaatcgaggc aaattacaaa tattcaatta gagtattggc aatcttgcct
     9961 ataataatgc taaaatcata atatataaaa tgataactta ttggaggaat aatgaatggc
    10021 aactatttca gcaaaacttg ttaaagaatt acgtgaaaaa actggcgcgg gtatgatgga
    10081 ttgtaaaaaa gcgctaactg aaactgatgg tgacatcgat aaagcgattg actacctacg
    10141 tgaaaaaggt attgctaaag cagctaaaaa agcagaccgt attgcggctg aaggtttagt
    10201 acatgtagaa actaaaggta acgacgcagt tatcgttgaa atcaactctg aaacagactt
    10261 tgttgctcgt aacgaaggtt tccaagagtt agttaaagaa atcgctaatc aagtattaga
    10321 tacaaaagct gaaactgttg aagctttaat ggaaacaact ttaccaaatg gtaaatcagt
    10381 tgatgaaaga attaaagaag caatttcaac aatcggtgaa aaattaagtg ttcgtcgttt
    10441 tgctatcaga actaaaactg ataacgatgc tttcggcgct tacttacaca tgggtggacg
    10501 cattggtgta ttaacagttg ttgaaggttc aactgacgaa gaagcagcaa gagacgttgc
    10561 tatgcatatc gctgcaatca accctaaata tgtttcttct gaacaagtta gcgaagaaga
    10621 aatcaaccac gaaagagaag ttttaaaaca acaagcatta aatgaaggta aaccagaaaa
    10681 catcgttgaa aaaatggtgg aaggacgttt acgtaaatac ttacaagaaa tttgtgctgt
    10741 agatcaagac ttcgttaaaa accctgatgt aacagttgaa gctttcttaa aaacaaaagg
    10801 tggaaaactt gttgacttcg tacgctatga agtaggcgaa ggtatggaaa aacgcgaaga
    10861 aaactttgcg gatgaagtta aaggacaaat gaaataatct gtcataaagt aaaacaagga
    10921 agaagacacc tttaatgttg ctttattaaa atgtaaatca ttctaataaa acgacaactg
    10981 tgtcttcttt acttgtatat gttacatata ttcacgatag agaggataag aaaatggctc
    11041 aaatttctaa atataaacgt gtagttttga aactaagtgg tgaagcgtta gctggagaaa
    11101 aaggatttgg cataaatcca gtaattatta aaagtgttgc tgagcaagtg gctgaagttg
    11161 ctaaaatgga ctgtgaaatc gcagtaatcg ttggtggcgg aaacatttgg agaggtaaaa
    11221 caggtagtga cttaggtatg gaccgtggaa ctgctgatta catgggtatg cttgcaactg
    11281 taatgaatgc cttagcatta caagatagtt tagaacaatt ggattgtgat acacgagtat
    11341 taacatctat tgaaatgaag caagtggctg aaccttatat tcgtcgtcgt gcaattagac
    11401 acttagaaaa gaaacgtgta gttatttttg ctgcaggtat tggaaaccca tacttctcta
    11461 cagatactac agcggcatta cgtgctgcag aagttgaagc agatgttatt ttaatgggca
    11521 aaaataatgt agatggtgta tattctgcag atcctaaagt aaacaaagat gcggtaaaat
    11581 atgaacattt aacgcatatt caaatgcttc aagaaggttt acaagtaatg gattcaacag
    11641 catcctcatt ctgtatggat aataacattc cgttaactgt tttctctatt atggaagaag
    11701 gaaatattaa acgtgctgtt atgggtgaaa agataggtac gttaattaca aaataaattt
    11761 agaggtgtaa aataatgagt gacattatta atgaaactaa atcaagaatg caaaaatcaa
    11821 tcgaaagctt atcacgtgaa ttagctaata tcagtgcagg aagagctaat tcaaatttat
    11881 taaacggcgt aacagttgat tactatggtg caccaacacc tgtacaacaa ttagcaagca
    11941 tcaatgttcc agaagcacgt ttacttgtta tttctccata cgacaaaact tctgtagctg
    12001 acatcgaaaa agcgataata gcggctaact taggtgtcaa cccaacaagt gatggtgaag
    12061 tgatacgtat tgcagtacct gccttaacag aagagcgtag aaaagagcgc gttaaagatg
    12121 ttaagaaaat tggtgaagaa gctaaagtat ctgttcgaaa tattcgtcgt gatatgaatg
    12181 atcagttgaa aaaagatgaa aaaaatggcg acattactga agatgagttg agaagtggta
    12241 ctgaagatgt tcagaaagca acagacaatt caataaaaga aattgatcaa atgattgctg
    12301 ataaagaaaa agatattatg tcagtataaa actaatatac aatgacatat taaaatgcca
    12361 gtattaaacg ataatgtaac atttaaaatg ggcatgttta attaaatcaa agatgcatgt
    12421 gataatttaa attcacaatg agcataaaaa tggtgtttaa acaagttaat taaacatata
    12481 ctttataaat aataggcatt aggtatattg ctataataaa gttatgtaat ttttaacctc
    12541 agtatgtatg tcacatttct ggtgtaaact gtaccgagtc agactttggt acagtttttt
    12601 tatttgctta ttcaatgcat taaatgagta tgataaaatg ataatgattg tttagtaact
    12661 tatactatat gacagagatg atcaggctcg gaggaaagac catgtttaaa aagctaataa
    12721 ataaaaagaa cactataaat aattataatg aagaattaga ctcgtctaat atacctgaac
    12781 atatcgctat tattatggat ggtaatgggc gatgggctaa gaagcgaaaa atgcctagaa
    12841 ttaaaggcca ttacgaaggt atgcaaacaa taaaaaaaat tactaggata gctagtgata
    12901 ttggtgttaa gtacttaact ttatatgcct tttccactga aaattggtca agacctgaaa
    12961 gtgaagtaaa ttatattatg aatttgcctg tcaatttctt aaagacattc ttaccggaac
    13021 taattgaaaa aaatgtcaaa gttgaaacaa ttggatttac tgataagttg ccaaaatcaa
    13081 cgatagaagc aattaataat gctaaagaaa agacagctaa taataccggc ttaaaattaa
    13141 tatttgcaat taattatggt ggcagagcag aacttgttca tagtattaaa aatatgtttg
    13201 acgagcttca tcaacaaggt ttaaatagtg atatcataga tgaaacatat ataaacaatc
    13261 atttaatgac aaaagactat cctgatccag agttgttaat tcgtacttca ggagaacaaa
    13321 gaataagtaa tttcttgatt tggcaagttt cgtatagtga atttatcttt aatcaaaaat
    13381 tatggcctga ctttgacgaa gatgaattaa ttaaatgtat aaaaatttat cagtcacgtc
    13441 aaagacgctt tggcggattg agtgaggagt agtatagtat gaaagttaga acgctgacag
    13501 ctattattgc cttaatcgta ttcttgccta tcttgttaaa aggcggcctt gtgttaatga
    13561 tatttgctaa tatattagca ttgattgcat taaaagaatt gttgaatatg aatatgatta
    13621 aatttgtttc agttcctggt ttaattagtg cagttggtct tatcatcatt atgttgccac
    13681 aacatgcagg gccatgggta caagtaattc aattaaaaag tttaattgca atgagcttta
    13741 ttgtattaag ttatactgtc ttatctaaaa acagatttag ttttatggat gctgcatttt
    13801 gcttaatgtc tgtggcttat gtaggcattg gttttatgtt cttttatgaa acgagatcag
    13861 aaggattaca ttacatatta tatgcctttt taattgtttg gcttacagat acaggggctt
    13921 acttgtttgg taaaatgatg ggtaaacata agctttggcc agtaataagt ccgaataaaa
    13981 caatcgaagg attcataggt ggcttgttct gtagtttgat agtaccactt gcaatgttat
    14041 attttgtaga tttcaatatg aatgtatgga tattacttgg agtgacattg attttaagtt
    14101 tatttggtca attaggtgat ttagtggaat caggatttaa gcgtcatttc ggcgttaaag
    14161 actcaggtcg tatactacct ggacacggtg gtattttaga ccgatttgac agctttatgt
    14221 ttgtgttacc attattaaat attttattaa tacaagctta atgctgagaa caaatcaata
    14281 aacgtaaaga ggagttgctg agataattta atgaatctca gaactccttt tgaaaattat
    14341 acgcaatatt aactttgaaa attagacgtt atattttgtg atttgtcagt atcatattat
    14401 aatgacttat gttacgtata cagcaatcaa ttttaaaata aaagaaattt ataaacaatc
    14461 gaggtgtagc gagtgagcta tttagttaca ataattgcat ttattattgt ttttggtgta
    14521 ctagtaactg ttcatgaata tggccatatg ttttttgcga aaagagcagg cattatgtgt
    14581 ccagaatttg cgatcggtat ggggccaaaa atttttagtt ttagaaaaaa tgaaacactt
    14641 tacactatta ggttattgcc tgttggtgga tatgttcgta tggcaggaga tggcttagaa
    14701 gagccaccag tcgagcccgg tatgaacgtt aaaattaaac tgaatgaaga aaatgaaata
    14761 acacatatca tattagatga tcatcataag tttcaacaaa ttgaagcgat cgaagttaaa
    14821 aaatgtgatt ttaaggatga cttattcata gaaggtatca ctgcttatga taatgaaaga
    14881 catcatttta aaattgctag aaagtctttc tttgttgaaa atggtagctt agttcaaatt
    14941 gctccgagag acagacaatt tgcacataaa aagccatggc cgaaattttt aacattattt
    15001 gcgggaccgt tatttaactt tatattagct ttagtcctat ttattggtct tgcatattat
    15061 caaggtacac ctacgtctac tgtagaacaa gtcgcagata agtatccagc acaacaagca
    15121 ggattacaaa aaggtgataa aattgttcaa attggcaaat ataaaatatc tgaatttgat
    15181 gatgttgata aggcgttaga taaagttaaa gataataaga cgactgttaa atttgaacgt
    15241 gatggtaaaa cgaagtcagt tgaattaaca cctaaaaaga ctgaaagaaa actgactaaa
    15301 gtaagttcag agacgaagta tgttctcgga ttccaaccag cgagtgaaca tacacttttt
    15361 aaaccaattg tattcggatt taaaagcttt ttaatcggta gtacttatat ttttacagct
    15421 gtagtaggta tgttggctag tatatttacg ggcggattct catttgatat gttaaatggt
    15481 ccggttggta tttatcataa cgtagactca gttgttaaag cgggtatcat tagcttaatt
    15541 ggttacactg cgttattaag tgtaaactta ggtattatga atttaattcc tattcctgca
    15601 ctagacggtg gtcgtatttt atttgttata tatgaagcga ttttcagaaa accagttaat
    15661 aaaaaagcgg aaacaacgat tattgctatt ggtgccattt tcatggtcgt tattatgata
    15721 ttagtaacgt ggaatgatat tcgacgatat ttcttataat ttaggaggat aaataattat
    15781 gaagcaatcc aaagttttta taccaacgat gcgtgacgtg ccatcagaag cagaagcaca
    15841 aagtcatcgt ttattattga aatcgggttt gataaaacaa agtacaagtg ggatttatag
    15901 ttatttaccg ctagcaacac gtgtgttaaa taatattact gcaattgtgc gacaagaaat
    15961 ggaacgtatc gattctgttg aaattttaat gccagcgtta caacaagctg aattatggga
    16021 agaatcagga cgttggggtg catatggccc agaattaatg cgtttacaag atagacatgg
    16081 aagacaattt gcattaggtc caacacatga agaattagtt acatcaatag taagaaatga
    16141 attgaaatca tacaaacaat taccgatgac attattccaa attcaatcta aattccgtga
    16201 tgaaaagaga ccacgttttg gtttacttcg tggtcgtgaa tttattatga aagatgcgta
    16261 ttcattccat gctgacgagg catcattaga tcaaacgtat caagatatgt atcaagcgta
    16321 tagccgtatt tttgagagag ttggcattaa cgcaagacca gtagttgcag attcaggtgc
    16381 tattggcggt agccatacac atgaatttat ggcattaagt gctatcggtg aggatacaat
    16441 cgtttacagt aaagaaagcg attatgctgc taacatcgaa aaagcagaag tcgtttacga
    16501 accaaatcat aagcatacta ctgtgcaacc tatagaaaaa attgaaacac caaatgttaa
    16561 gactgcgcaa gaattggcag actttttagg tagaccagta gatgaaatcg ttaaaacgat
    16621 gattttcaaa gttgatggcg aatatattat ggttttagtg cgtggacatc atgaaattaa
    16681 tgacattaaa ttaaaatctt atttcggcac agataatatt gaattagcaa cacaagacga
    16741 aattgttaat ttagttggtg caaatcctgg ttcactaggt cctgtaattg ataaagaaat
    16801 caaaatttat gcagataatt ttgtgcaaga tttaaataat ttagttgtcg gtgctaacga
    16861 agatggttat cacttaatta atgtaaatgt aggtagagac ttcaacgttg atgcatatgg
    16921 cgatttccgt tttattttag aaggcgaaaa gttaagtgat ggttcaggcg ttgcacattt
    16981 tgctgaaggt attgaagttg gtcaagtatt taaattgggt actaagtatt cagaatcaat
    17041 gaatgctaca ttcttagata atcaaggaaa agctcaaccg ttaattatgg gttgttatgg
    17101 tattggaatt tctagaacgc taagtgcaat tgttgaacaa aatcacgatg ataatggtat
    17161 tgtttggcct aaatcagtta ctccatttga tttacattta atttctatta atcctaagaa
    17221 agatgatcaa cgagaactag cggatgcact atatgctgaa tttaatacta aatttgatgt
    17281 gttgtacgat gatcgtcagg aacgtgcggg tgtcaaattt aatgatgccg atttaattgg
    17341 tttaccactg cgaattgttg ttggtaaacg tgcatcggaa ggtattgtag aagttaaaga
    17401 acgtttaaca ggtgatagcg aagaagtcca cattgatgac ttaatcactg tcattacaaa
    17461 taaatatgat aacttaaaat aattaagatc gaatgaatta taagagtagg aaaaagctga
    17521 aagaaatcag atgcttatgt cctgctctta ttatttttga tataatgatt attcgatgaa
    17581 aaatgactga agacatagta taattaaaga taaatttgtt ttaacaatat tatgattagc
    17641 caaatataaa gcatttaatt ttctatcatt actatgctca cataatctaa atattgttcg
    17701 aacacgtaaa agtaatttct atttaaggtg gtaattgtct tggcaatgac agagcaacaa
    17761 aaatttaaag tgcttgctga tcaaattaaa atttcaaatc aattagatgc tgaaatttta
    17821 aattcaggtg aactgacacg tatagatgtt tctaacaaaa acagaacatg ggaatttcat
    17881 attacattac cacaattctt agctcatgaa gattatttat tatttataaa tgcaatagag
    17941 caagagttta aagatatcgc caacgttaca tgtcgtttta cggtaacaaa tggcacgaat
    18001 caagatgaac atgtaattaa atactttgga cactgtattg accaaacagc tttatctcca
    18061 aaagttaaag gtcaattgaa acagaaaaag cttattatgt ctggaaaagt attaaaagta
    18121 atggtatcaa atgacattga acgtaatcat tttgataagg catgcaatgg aagtcttatc
    18181 aaagcgttta gaaattgtgg ttttgatatc gataaaatca tattcgaaac aaatgataat
    18241 gatcaagaac aaaacttagc ttctttagaa gcacatatac aagaagaaga cgaacaaagt
    18301 gcacgattgg caacagagaa acttgaaaaa atgaaagctg aaaaagcgaa acaacaagat
    18361 aacaacgaaa gtgctgtcga taagtgtcaa attggtaagc cgattcaaat tgaaaatatt
    18421 aaaccaattg aatctattat tgaggaagag tataaagttg caatagaggg tgtcattttt
    18481 gatattaact taaaagaact taaaagtggt cgtcatatcg tagaaattaa agtgactgac
    18541 tatacggact ctttagtttt aaaaatgttt actcgtaaaa acaaagatga tttagaacat
    18601 tttaaagcgc taagtgttgg taaatgggtt agggctcaag gtcgtattga agaagataca
    18661 tttattagag atttagttat gatgatgtct gatattgaag agattaaaaa agcgacaaaa
    18721 aaagataagg ctgaagaaaa gcgtgtagaa ttccacttgc atactgcaat gagtcaaatg
    18781 gatggtatac caaatattag tgcgtatgtt aaacaggcag cagactgggg acatccagcc
    18841 attgcggtta cagaccataa tgttgtgcaa gcatttccag atgctcacgc agcagcggaa
    18901 aaacatggta ttaaaatgat atacggtatg gaaggtatgt tagttgatga tggtgttccg
    18961 attgcataca aaccacaaga tgtcgtatta aaagatgcta cttatgttgt attcgacgtt
    19021 gagacaactg gtttatcaaa tcagtatgat aaaatcatcg agcttgcagc tgtgaaagtt
    19081 cataacggcg aaatcatcga taagtttgaa aggtttagta atccgcatga acgattatcg
    19141 gaaacgatta tcaatttgac gcatattact gatgatatgt tagtagatgc ccctgagatt
    19201 gaagaagtac ttacagaatt taaagaatgg gttggcgatg cgatattcgt agcacataat
    19261 gcttcgtttg atatgggctt catcgacacg ggatatgaac gtcttggatt tggaccatct
    19321 acgaatggtg ttatcgatac attagaatta tctcgtacga ttaatactga atatggtaaa
    19381 catggtttaa atttcttagc taaaaaatac ggtgtagaat taacgcaaca tcaccgtgcc
    19441 atttatgata cagaggcaac agcttacatt ttcataaaaa tggttcaaca aatgaaagaa
    19501 ttaggcgtat taaatcataa cgaaatcaac aaaaaactca gtaatgaaga tgcatataaa
    19561 cgtgcaagac ctagtcatgt cacattaatt gtacaaaacc aacaaggtct taaaaatcta
    19621 tttaaaattg taagtgcatc attagtgaag tatttctacc gtacgcctcg aattccacgt
    19681 tcattgttag atgaatatcg tgagggatta ttggtaggta cagcgtgtga tgaaggtgaa
    19741 ttatttacgg cagttatgca gaaggaccag agccaagttg aaaaaattgc caaatattat
    19801 gattttattg aaattcaacc accggcactt tatcaagatt taattgatag agagcttatt
    19861 agagatactg aaacattaca tgaaatttat caacgtttaa tacatgcagg tgacacagcg
    19921 ggtattcctg ttattgcgac aggaaatgca cactatttgt ttgaacatga tggtatcgca
    19981 cgtaaaattt taatagcatc acaacccggc aatccactta atcgctcaac tttaccggaa
    20041 gcacatttta gaactacaga tgaaatgtta aacgagtttc attttttagg tgaagaaaaa
    20101 gcgcatgaaa ttgttgtgaa aaatacaaac gaattagcag atcgaattga acgtgttgtt
    20161 cctattaaag atgaattata cacaccgcgt atggaaggtg ctaacgaaga aattagagaa
    20221 ctaagttatg caaatgcgcg taaattgtat ggtgaagacc tgcctcaaat cgtaattgat
    20281 cgattagaaa aagaattaaa aagtattatc ggtaatggat ttgcggtaat ttacttaatt
    20341 tcgcaacgtt tagttaaaaa atcattagat gatggatact tagttggttc ccgtggttca
    20401 gtaggttcta gttttgtagc gacaatgact gagattactg aagtaaaccc gttaccgcca
    20461 cactatattt gtccgaactg taaaaggagt gaatttttca atgatggttc agtaggatca
    20521 ggattcgatt tacctgataa gacgtgtgaa acttgtggag cgccacttat taaagaagga
    20581 caagatattc cgtttgaaac atttttagga tttaaaggag ataaagttcc tgatatcgac
    20641 ttaaacttta gtggtgaata tcaaccgaat gcccataact acacaaaagt attatttggt
    20701 gaggataaag tattccgtgc aggtacaatt ggtaccgttg ctgaaaagac tgcttttggt
    20761 tatgttaaag gttatttgaa tgatcaaggc atccacaaaa gaggcgctga aatagatcga
    20821 ctcgttaaag gatgtacagg tgttaaacgt acaaccggac agcatccagg gggtattatt
    20881 gtagtacctg attacatgga tatttatgat tttacgccga tacaatatcc tgccgatgat
    20941 caaaattcag catggatgac gacacatttt gatttccatt ctattcatga taatgtatta
    21001 aaacttgata tacttggaca tgatgatcca acaatgattc gtatgcttca agatttatca
    21061 ggaattgatc caaaaacaat acctgtagat gataaagaag ttatgcagat ttttagtaca
    21121 cctgaaagtt tgggtgttac tgaaaatgaa attttatgta aaacaggtac atttggagta
    21181 ccagaattcg gtacaggatt cgtgcgtcaa atgttagaag atacaaagcc aacaacattt
    21241 tctgaattag ttcaaatctc aggattatct catgggacag atgtgtggtt aggcaatgct
    21301 caagaattaa ttaaaaccgg tatatgtgat ttatcaagtg taattggttg tcgtgatgat
    21361 atcatggttt atttaatgta tgctggttta gaaccatcaa tggcttttaa aataatggag
    21421 tcagtacgta aaggtaaagg tttaactgaa gaaatgattg aaacgatgaa agaaaatgaa
    21481 gtgccggatt ggtatttaga ttcatgtctt aaaattaagt acatgttccc taaagcccat
    21541 gcagcagcat acgttttaat ggcagtacgt atcgcatatt tcaaagtaca tcatccactt
    21601 tattactatg catcttactt tacaattcgt gcgtcagact ttgatttaat aacgatgatt
    21661 aaagataaaa caagcattcg aaatactgta aaagacatgt attctcgcta tatggatcta
    21721 ggtaaaaaag aaaaagacgt attaactgtc ttggaaatta tgaatgaaat ggcgcatcga
    21781 ggttatcgaa tgcaaccgat tagtttagaa aagagtcagg cgttcgaatt tatcattgaa
    21841 ggcgatacac ttattccgcc gttcatatca gtgcctgggc ttggcgaaaa cgttgcgaaa
    21901 cgaattgttg aagctcgtga cgatggacca tttttatcaa aagaagattt aaacaaaaaa
    21961 gctggattat ctcagaaaat tattgagtat ttagatgagt taggctcatt accgaattta
    22021 ccagataaag ctcaactttc gatattcgat atgtaaaatg aaataattaa gctatttatt
    22081 taatgcgtat ggcatagtcg aagaaataca aaattgttgc tggacacaaa gttatgcctg
    22141 tattttttta gcgtcttacg agtctattcg aatgtaatgg tgaaataaat gaacaaactt
    22201 ttacaagaat ctctgattaa tagtgaagtc atttgtttca agcataaact tatgctataa
    22261 ttaagttgct taaaaattag tgaactcagg cagaagagtg ggagattccc gctcttttct
    22321 atttgccaaa aagggaggcc tgtatgagta aaattacaga acaagtagaa gtgatcgttc
    22381 aaccaataat ggaagacttg aattttgaac ttgtagacgt tgaatatgtc aaagagggta
    22441 gagatcattt tcttagaatc tctattgata aagaaggtgg cgtagattta aatgattgta
    22501 cgctagcttc tgaaaaaata agtgaagcta tggatgcaaa tgatcctatt cctgaaatgt
    22561 attatttaga cgtagcgtca cctggtgcag aacgtccaat taaaaaagaa caagatttcc
    22621 aaaatgcaat aactaaacct gtatttgttt ctttatatgt accaattgaa ggtgaaaagg
    22681 aatggttagg cattttacaa gaagtcaata atgaaacaat tgtagtacaa gttaaaatca
    22741 aagcaagaac gaaagatata gagataccga gagacaaaat agcaaaagca cgtcacgcag
    22801 ttatgattta acgtgatgag gaggaaaaaa cgtgtcaagt aatgaattat tattagctac
    22861 tgagtattta gaaaaagaaa agaagattcc tagagcagta ttaattgatg ctattgaagc
    22921 agctttaatt actgcataca aaaagaatta tgatagtgca agaaatgtcc gtgtggaatt
    22981 aaatatggat caaggtactt tcaaagttat cgctcgtaaa gatgttgttg aagaagtatt
    23041 tgacgacaga gatgaagtgg atttaagtac agcgcttgtt aaaaaccctg catatgaaat
    23101 tggtgatata tacgaagaag atgtaacacc taaagatttt ggtcgtgtag gtgctcaagc
    23161 agcgaaacaa gcagtaatgc aacgtcttcg tgatgctgaa cgtgaaattt tatttgaaga
    23221 atttatagac aaagaagaag acatacttac tggaattatt gaccgtgttg accatcgtta
    23281 tgtatatgtg aatttaggtc gtatcgaagc tgttttatct gaagcagaaa gaagtcctaa
    23341 cgaaaaatat attcctaacg aacgtatcaa agtatatgtt aacaaagtgg aacaaacgac
    23401 aaaaggtcct caaatctatg tttctcgtag ccatccaggt ttattaaaac gtttatttga
    23461 acaagaagtt ccagaaattt acgatggtac tgtaattgtt aaatcagtag cacgtgaagc
    23521 tggcgatcgc tctaaaatta gtgtcttctc tgaaaacaat gatatagatg ctgttggtgc
    23581 atgtgttggt gccaaaggcg cgcgtgttga agctgttgtt gaagagctag gtggcgaaaa
    23641 aatcgacatc gttcaatgga atgaagatcc aaaagtattt gtaaaaaatg ctttaagccc
    23701 ttctcaagtt ttagaagtta ttgttgatga aacaaatcaa tctacggtag ttgttgttcc
    23761 agattatcaa ttgtcattag cgattggtaa aagaggacaa aacgcacgtc tagctgctaa
    23821 attaaccggc tggaaaattg atattaaatc agaaacagat gcgcgtgaag cgggtatcta
    23881 tccagtagtt gaagctgaaa aagtaactga agaagatatt gctttagaag atgctgacac
    23941 aacagaatca accgaagagg taaatgatgt ttcagttgaa acaaatgtag agaaagaatc
    24001 tgaataatag gttggagtga agtatctatg aaaaagaaaa aaattccgat gcgaaaatgt
    24061 attctttcaa atgaaatgca tcccaaaaaa gatatgattc gtgttgttgt taataaagaa
    24121 ggcgaaatct ttgcggatgt tactggaaag aaacaaggcc gtggcgcata tgtttctaaa
    24181 gatgttgcta tggttgaaaa agcacaacaa aaagaaattt tagaaaaata ttttaaagca
    24241 tctaaagagc aattggatcc tgtttacaaa gaaattatta gattaattta tagagaagaa
    24301 atcccaaaat gagtatagat caaatattaa actttttagg attagcaatg agagctggta
    24361 aagtaaaaac aggtgaatca gtcattgtta atgagattaa aaaaggaaat ttgaagctcg
    24421 ttattgttgc aaatgatgcg tctgataata cagctaaatt aattacagat aaatgtaaga
    24481 gttacaaagt tccattcaga aagtttggaa atcgaaatga attgggaata gcacttggaa
    24541 aaggtgagcg tgttaatgta gggattactg acccaggctt tgctaaaaag ttgctatcaa
    24601 tgatagatga atatcataag gagtgattat atgagtaaac aaagaattta cgaatatgcg
    24661 aaagaattaa atctaaagag taaagagatt atagatgagt taaaaagcat gaatattgag
    24721 gtttcaaatc atatgcaagc tttggaagat gaccaaatta aagcattaga taaaaagttc
    24781 aaaaaagaac aaaagaacga caataaacaa agcactcaaa ataatcacca aaaatcaaac
    24841 aatcaaaacc aaaataaagg gcaacaaaaa gataacaaaa agaatcaaca acaaaataat
    24901 aaaggcaaca aaggcaataa aaagaataat agaaataata agaaaaataa caagaataat
    24961 aaaccacaaa atcaaccagc tgctccaaaa gaaataccat caaaagtgac atatcaagaa
    25021 ggtattacag taggcgaatt tgcggataaa ttaaatgttg aatcatccga aattatcaaa
    25081 aaattattct tacttggtat tgttgctaat atcaatcaat cattaaatca agaaacaatc
    25141 gaattaattg ccgatgatta tggcgttgag gttgaagaag aagttgtgat taatgaagaa
    25201 gatttatcaa tctactttga agacgaaaaa gatgatccag aagcaattga gagaccagca
    25261 gttgtaacaa ttatgggaca tgttgaccat ggtaaaacga ctttattaga ttcaattcgt
    25321 catacaaaag ttacagcagg tgaagcaggc ggaatcactc aacatattgg tgcatatcaa
    25381 attgaaaacg atggcaaaaa aatcactttc ttagatacac cgggacatgc tgcatttaca
    25441 acgatgcgtg cgcgtggtgc acaagtaaca gatattacaa ttttagtagt tgcagctgac
    25501 gatggtgtta tgccacaaac aattgaagca attaaccatg ctaaagaagc agaagtacca
    25561 attattgttg cagtaaataa aattgataaa ccaacttcaa atcctgatcg agttatgcaa
    25621 gaattaactg aatatggttt aattcctgaa gattggggcg gcgaaacaat tttcgttcca
    25681 ctttctgcat taagtggtga tggtatcgac gatttattag aaatgatagg attagttgca
    25741 gaagttcaag aacttaaagc aaatcctaaa aaccgtgctg ttggtacagt tatcgaagct
    25801 gaattagata aatcacgtgg tccttctgca tcattattag tacaaaatgg tacattaaat
    25861 gttggtgatg cgattgtagt tggtaatact tacggccgta tccgtgcaat ggttaatgac
    25921 ttaggtcaaa gaatcaaaac ggctggtcca tcaacgcctg ttgaaattac aggtattaat
    25981 gatgtgccac aagctgggga tcgctttgtt gtatttagtg atgaaaaaca agctcgtcgt
    26041 attggtgaat caagacacga agctagcatt gtacaacaac gtcaagaaag taaaaatgtt
    26101 tcattagata acctgtttga acaaatgaaa caaggtgaaa tgaaagattt aaacgttatt
    26161 attaaaggtg atgttcaagg ttctgttgaa gctttagctg catcattaat gaaaattgat
    26221 gttgaaggcg taaatgttcg tatcattcat acagcggttg gtgcaattaa tgagtcagac
    26281 gtgacacttg ctaatgcctc aaatggtatt atcattggtt tcaatgttcg tccagacagt
    26341 ggtgcaaaac gtgctgcaga agctgaaaat gttgatatgc gtttacacag agttatttat
    26401 aatgttatcg aagaaattga atcagcgatg aaaggtttac ttgatccaga atttgaagaa
    26461 caagttatcg gacaagctga agttcgtcaa acattcaaag tttctaaagt tggtactatt
    26521 gctggatgtt atgttactga aggtaaaatt acgcgaaatg ctggtgtacg tattattcgt
    26581 gatggtattg ttcaatatga aggcgaatta gatacactta aacgtttcaa agatgatgct
    26641 aaggaagttg caaaaggtta tgaatgtggt attacaattg aaaactacaa tgaccttaaa
    26701 gaaggcgatg ttatcgaagc atttgaaatg gttgaaatta agcgttaatt aaataaatta
    26761 caagctaaaa gtatagttaa gattgatatg ctccctataa atattgcact ttttaagtgt
    26821 ctactttata gggagcatat ttgatactag cttttggttt tttattagaa tagattacct
    26881 attaaaagtt acgttatatg gacatgattt tgtataaaat tttgtggtgg cctagaatga
    26941 tttttaatga caaaatataa tgtcgactat tattggaaaa ttttctgttg aaatgcctat
    27001 cttacggcaa actttatttg attttatagg cttaatttat taaaataacg tgtgagctaa
    27061 aataattgtt taagcattgt tacactaaaa aatgcaaata acaattgaac ttaaagataa
    27121 agaggtgaca agaatgagca gtatgagagc agagcgtgtt ggtgaacaaa tgaagaagga
    27181 attaatggat atcatcaaca ataaagtcaa agatcctcga gttggtttta ttacaattac
    27241 agatgttgtt ttaacaaatg atttatcgca ggctaaagta tttttaactg tattaggtaa
    27301 cgataaagaa gtagaaaata catttaaagc acttgataaa gcaaaaggct tcattaagtc
    27361 tgaattaggt tctagaatgc gattacgtat tatgccggaa ttaatgtatg aatatgatca
    27421 atcaatcgaa tatggtaata aaattgaacg aatgattcaa gatttacaca aacaagatag
    27481 ataatttagt gttaggtatc tggaaaatgt ttgataattt cttaatatcg gtatattaac
    27541 attaaacagt taatacatag atgtgtagaa atagttaaca ttttccagtt tttttatgaa
    27601 taaattcagt tgaaacgcta ttaaaatata ttttaaaaaa gaaggtgact atatgtataa
    27661 tgggatatta ccagtatata aagagcgcgg tttaacaagt catgacgttg tattcaaatt
    27721 gcgtaaaata ttaaaaacta aaaaaatagg tcacacgggt acgcttgatc ccgaagttgc
    27781 aggcgtgtta ccggtatgta taggtaatgc aacgagagtt agtgattatg ttatggatat
    27841 gggcaaagct tatgaagcaa ctgtatcgat aggaagaagt acaacgactg aagatcaaac
    27901 gggtgataca ttggaaacaa aaggtgtaca ctcagcagat tttaataagg acgatattga
    27961 ccgattgtta gaaagtttta aaggtatcat tgaacaaatt ccgccgatgt actcatccgt
    28021 caaagtaaat ggtagaaaat tatatgaata tgcgcgtaat aatgaaacag ttgaaagacc
    28081 aaagcgtaaa gttaatatta aagacattgg gcgtatatct gaattagatt ttaaagaaaa
    28141 tgagtgtcat tttaaaatac gcgtcatctg tggtaaaggt acatatatta gaacgctagc
    28201 aactgatatt ggtgtgaaat taggctttcc ggcacatatg tcgaaattaa cacgaatcga
    28261 gtctggtgga tttgtgttga aagatagcct tacattagaa caaataaaag aacttcatga
    28321 gcaggattca ttgcaaaata aattgtttcc tttagaatat ggattaaagg gtttgccaag
    28381 cattaaaatt aaagattcgc acataaaaaa acgtatttta aatgggcaga aatttaataa
    28441 aaatgaattt gataacaaaa ttaaagacca aattgtattt attgatgatg attcagaaaa
    28501 agtattagca atttatatgg tacaccctac aaaagaatca gaaattaaac ctaaaaaagt
    28561 ctttaattaa aggagataga atttatgaaa gtcatagaag tgacacatcc tatacaatct
    28621 aaacagtata ttacagagga tgttgcaatg gcattcggat ttttcgatgg catgcataaa
    28681 ggtcatgaca aagtctttga tatattaaac gaaatagctg aggcacgcag tttaaaaaaa
    28741 gcggtgatga catttgatcc gcatccatct gtcgtgttga atcctaaaag aaaacgaaca
    28801 acgtatttaa cgccactttc agataaaatc gaaaaaatta gccaacatga tattgattat
    28861 tgtatagtgg ttaatttttc atctaggttt gctaatgtga gcgttgaaga ttttgttgaa
    28921 aattatataa ttaaaaataa tgtaaaagaa gtcattgctg gttttgattt tacttttggt
    28981 aaatttggaa aaggtaatat gactgttctt caagaatatg atgcgtttaa tacgacaatt
    29041 gtgagtaaac aagaaattga aaatgaaaaa atttctacaa cttctattcg tcaagattta
    29101 atcaatggtg agttgcaaaa agcgaatgat gctttaggct atatatattc tattaaaggc
    29161 actgtagtgc aaggtgaaaa aaggggaaga actattggct tcccaacagc taacattcaa
    29221 cctagtgatg attatttgtt gcctcgtaaa ggtgtttatg ctgttagtat tgaaatcggc
    29281 actgaaaata aattatatcg aggggtagct aacataggtg taaagccaac atttcatgat
    29341 cctaacaaag cagaagttgt catcgaagtg aatatctttg actttgagga taatatttat
    29401 ggtgaacgag tgaccgtgaa ttggcatcat ttcttacgtc ctgagattaa atttgatggt
    29461 atcgacccat tagttaaaca aatgaatgat gataaatcgc gtgctaaata tttattagca
    29521 gttgattttg gtgatgaagt agcttataat atctagagtt gcgtatagtt atataaacaa
    29581 tctataccac acctttttct tagtaggtcg aatctccaac gcctaactcg gattaaggag
    29641 tattcaaaca ttttaaggag gaaattgatt atggcaattt cacaagaacg taaaaacgaa
    29701 atcattaaag aataccgtgt acacgaaact gatactggtt caccagaagt acaaatcgct
    29761 gtacttactg cagaaatcaa cgcagtaaac gaacacttac gtacacacaa aaaagaccac
    29821 cattcacgtc gtggattatt aaaaatggta ggtcgtcgta gacatttatt aaactactta
    29881 cgtagtaaag atattcaacg ttaccgtgaa ttaattaaat cacttggtat ccgtcgttaa
    29941 tcttaatata acgtctttga ggttggggca tatttatgtt ccaaccttaa tttatattaa
    30001 aaaagctttt tacaaatatt aacatttatt atatgttaag ctaatattga gtgaataata
    30061 aggttacaat gagataaaga tgatataagt acacctagag taataatcaa gatattaaaa
    30121 ataaagtatg tttttttaaa aaatataact tatatttata ctgataaggg tgggacgata
    30181 agtctatttt gtaaataata gatggatatc ccgctctctt tttttccaat tcaatatttt
    30241 ataactaata ttaaaatacg ataataaatg atatgatata actattagat tcaagagagg
    30301 agatttataa tgtctcaaga aaagaaagtt tttaaaactg aatgggcagg aagatcttta
    30361 acgattgaaa cagggcaatt agctaaacaa gcaaatggcg ctgtattggt tcgttatgga
    30421 gatacagtcg tgttatcgac ggcaactgca tcaaaagaac ctcgtgatgg agatttcttc
    30481 ccattaacag tgaactatga agaaaaaatg tacgctgcgg gtaaaattcc tggtggattt
    30541 aaaaagagag aaggacgtcc tggtgacgat gcaacattaa ctgcgcgatt aattgataga
    30601 ccaattagac ctttattccc taaaggatat aagcatgatg ttcaaattat gaacatggta
    30661 ttaagtgcag atcctgattg ttcaccacaa atggctgcaa tgattggttc atctatggcg
    30721 cttagtgtgt cggatattcc attccaaggg ccaatcgccg gtgtaaatgt gggttatatt
    30781 gacggtaaat atatcattaa cccaacagta gaagaaaaag aagtttctcg tttagacctt
    30841 gaagtagctg gtcataaaga tgcagtaaac atggtagagg caggcgctag tgagattact
    30901 gaacaagaaa tgttagaggc gattttcttt ggtcatgaag agattcaacg tttagttgag
    30961 ttccaacaac aaatcgtcga ccacattcaa cctgttaaac aagaatttat tccagcagag
    31021 cgtgatgaag cgctagttga acgtgtaaaa tctttaaccg aagaaaaagg acttaaagaa
    31081 acagttttaa catttgataa acaacaacga gatgaaaatc ttgataactt aaaagaagaa
    31141 atcgtcaatg aatttatcga tgaagaagat ccagagaatg aattacttat taaagaagtt
    31201 tatgcaattt taaatgaatt agtgaaagaa gaagttcgac gtttaattgc agatgaaaaa
    31261 attagaccag acggccgtaa acctgatgaa atccgtccat tagattctga agttggtatt
    31321 ttacctagaa cgcatggttc aggtctattt acacgtggtc agactcaagc actttcagtt
    31381 ttaacattag gtgctttagg cgattatcaa ttaattgatg gtttaggacc tgaagaagaa
    31441 aaaagattca tgcatcatta taacttcccg aatttttcag taggtgaaac tggtccagta
    31501 cgtgcgccag gtcgtcgtga aattggacat ggtgcgttag gtgaaagagc attaaaatat
    31561 attattcctg atactgctga tttcccatat acaattcgta ttgtaagtga ggtacttgaa
    31621 tcaaacggtt catcatctca agcgtcaatt tgtggatcaa cattagcatt aatggatgcg
    31681 ggcgtaccga ttaaagcacc agttgctggt attgctatgg gccttgttac acgtgaagat
    31741 agctatacga ttttaactga tatccaaggt atggaagatg cattaggtga tatggacttt
    31801 aaagtcgctg gtactaaaga aggtattaca gcaatccaaa tggatattaa aattgatggt
    31861 ttaacgcgtg aaattatcga agaggctcta gaacaagcga gacgtggtcg tttagaaata
    31921 atgaatcata tgttacaaac aattgatcaa ccacgtactg aattaagtgc ttacgcgcca
    31981 aaagttgtaa ctatgacaat taaaccagat aagattagag atgttatcgg acctggtggt
    32041 aaaaaaatta acgaaattat tgatgaaaca ggcgttaaat tagatattga acaagatggt
    32101 actatcttta ttggggccgt tgatcaagct atgataaatc gtgctcgtga aatcattgag
    32161 gaaattacac gtgaagcgga agtaggtcaa acttatcaag ccactgttaa acgtattgaa
    32221 aaatacggtg cgtttgtagg cctattcccg ggtaaagatg cgttgcttca catttcacaa
    32281 atttcaaaaa atagaattga aaaagtggaa gatgtattaa aaatcggtga cacaattgaa
    32341 gttaagatta ctgaaattga taaacaaggt cgagtaaatg cttcacacag agcattagaa
    32401 gaataatatt taaagtcata tgacgacaat gtatcgtcat gtgatttttt tatgcaattt
    32461 tttacgaagt gatccatttt gaatttgttg tattgaacat tttaaaacgc tttattattt
    32521 tgtgtgtaac tgttaattat cctgtatgta tagtgattaa tagtgtacat caagtgtttt
    32581 ttaacttata atgaatagtg agtttatata tggacgggta acaaatttag gaggtaagat
    32641 tttgagttta ataaagaaaa agaataaaga tattcgcatt ataccattag gcggtgttgg
    32701 cgaaattgct aaaaatatgt atatcgttga agtagacgat gaaatgttta tgttagatgc
    32761 tggacttatg tttccagaag acgaaatgct aggtattgat attgttatac cagacatttc
    32821 atacgtactt gaaaataaag ataaattgaa gggtatattc cttacacacg gacatgagca
    32881 cgcgattggt gcagtgagtt atgttttaga acaattagat gcaccagtat atggatctaa
    32941 attgacaata gcgttaatta aagaaaatat gaaagcccgt aatattgata aaaaagttcg
    33001 ctactacaca gttaataatg attcaattat gagattcaaa aacgtgaata ttagtttctt
    33061 taatacgaca cacagtattc ctgatagttt aggtgtttgt attcatactt catatggtgc
    33121 cattgtgtat acaggtgaat ttaagtttga ccaaagttta catggacatt atgcaccaga
    33181 tattaaacgt atggcagaga ttggtgaaga aggcgtattt gtcttaatca gtgattctac
    33241 tgaggcagag aaacctggat ataatactcc ggaaaatgtg attgaacatc atatgtatga
    33301 cgcttttgca aaagtgcgag gtcgcttgat tgtttcatgt tatgcttcga actttatacg
    33361 tatacagcaa gttttaaata ttgctagcaa gctaaatcgt aaagtgtcat ttttaggaag
    33421 atcacttgaa agttcattta atattgctcg taaaatgggg tatttcgaca ttcctaaaga
    33481 tttgctaatt cctataacag aagttgataa ttatcctaaa aatgaagtga taattatagc
    33541 tactggtatg caaggagaac ctgtagaagc cttaagtcaa atggcgcaac ataagcataa
    33601 aattatgaat atcgaagaag gcgattctgt atttttagca attacggctt ctgctaatat
    33661 ggaagttatc attgcgaata cattaaatga gcttgtacgt gctggcgcac atattattcc
    33721 aaataacaag aagattcatg cttcaagtca tggttgcatg gaagaattaa aaatgatgat
    33781 taatattatg aaacctgaat actttattcc tgtacaaggt gaatttaaaa tgcagatagc
    33841 acatgcgaag ctagcagctg aagcaggtgt tgcaccagaa aagattttcc ttgtggaaaa
    33901 aggagatgtc attaattaca acggtaaaga tatgatatta aatgaaaagg taaattcagg
    33961 aaatatttta atagatggta ttggtattgg ggatgtagga aatatcgtgt tgagagaccg
    34021 tcatctttta gcagaagatg gtatctttat tgctgtagta acgttagatc ctaaaaatag
    34081 acgtatagct gcgggacctg aaattcaatc tcgtgggttt gtatatgtac gtgaaagtga
    34141 agacttatta cgtgaagcag aagagaaagt acgtgaaata gtagaggctg gtttacaaga
    34201 aaaacgcata gaatggtctg aaattaagca aaatatgcgt gatcaaatta gtaaactatt
    34261 attcgaaagt acaaaacgtc gtcctatgat tattccagta atttctgaaa tttaatcaaa
    34321 aagtcattaa cataaaagag gtcagaacaa gtcactgaaa tataatggtt gtcatggaca
    34381 atttacttat attttatgat ggtcaattaa aaggggtaac gattaatctg ttatcttaag
    34441 taaattgata catagatgat attgttctaa cctctttcat cgtctgtttg gactacatat
    34501 tctaaacatc aaataggaaa ttatatataa taacgtcgtt ttaactaagg caacataagg
    34561 aggtgcgtca attggcacaa gcaaaaaaga aatcgacagc taagaaaaaa acaacatcaa
    34621 aaaaaagaac aaattcgagg aaaaagaaga atgataatcc gatacgttat gtcatagcta
    34681 ttttagtagt tgtattaatg gtgttgggtg ttttccaatt aggaataata ggtcgtctaa
    34741 ttgacagctt ctttaattat ttatttgggt acagtagata tttaacatat attttagtac
    34801 tcttagcaac tggttttatt acatactcta aacgtattcc taaaactaga cgaacggctg
    34861 gttcgattgt attgcaaatt gcattgctat ttgtatcaca gttagttttt cattttaata
    34921 gtggtatcaa agctgaaaga gaacctgtac tttcttatgt gtatcagtca taccaacaca
    34981 gtcatttccc aaattttggt ggcggtgtat taggctttta tttattagag ttaagcgtac
    35041 ctttaatttc attatttggt gtatgtatta ttactatttt attattatgc tcaagtgtta
    35101 ttttattaac aaaccatcaa catcgtgaag tagcaaaagt tgtactggaa aatataaaag
    35161 cttggtttgg ttcatttaat gaaaaaatgt cggaaaaaaa ccaagaaaaa caattgaagc
    35221 gtgaagaaaa agcgagactt aaagaagaac aaaaggcacg tcaaaatgaa cagccacaaa
    35281 taaaagatgt gagtgatttt acggaagtgc ctcaagaaag agatattcca atttatgggc
    35341 atactgaaaa tgaaagtaaa agtcagagtc aaccaagtcg gaaaaagcga gtgttcgatg
    35401 cagagaatag ttcgaataac atcgtaaatc atcatcaagc agatcagcaa gaacaattaa
    35461 cagaacaaac tcataacagt gttgaaagtg aaaacactat tgaagaagct ggtgaagtta
    35521 cgaatgtatc gtatgttgtt ccaccgttaa ctttacttaa tcaacctgca aaacaaaaag
    35581 caacatctaa agctgaagtg caacgtaaag gacaagtact agagaataca ttaaaagatt
    35641 ttggggtaaa tgcaaaagtg acacaaatta aaattggtcc tgcagtaact caatatgaaa
    35701 ttcaaccagc tcaaggggtt aaagtgagta aaattgtaaa cctgcacaat gatatcgcat
    35761 tagctttagc agcaaaagat gttagaatcg aagcgccaat acctggtcgc tctgcagtag
    35821 gtattgaagt gccaaatgag aaaatttcat tagtttcact aaaagaagtt ttagatgaaa
    35881 aattcccgtc taataataaa ctagaagttg gattaggaag agatatatca ggtgatccaa
    35941 ttactgttcc actaaatgaa atgccacact tattggtggc aggatcgacg ggtagtggta
    36001 aatctgtttg tataaatggt attattacaa gtattttatt aaatgctaaa ccgcatgaag
    36061 ttaaacttat gttaatcgat ccgaaaatgg ttgaactaaa tgtttataac ggaattccac
    36121 atttattaat tccggttgtt acaaatcctc ataaagctgc tcaagcttta gaaaaaattg
    36181 tagctgagat ggaaagacgt tatgatttat tccaacattc atcaactaga aatattaaag
    36241 gttataacga attaatccgt aagcaaaatc aagaattaga tgagaagcaa ccagaattac
    36301 cttatatcgt tgttattgta gatgagcttg cagatttaat gatggtagct ggtaaagaag
    36361 ttgaaaatgc gattcaacgt atcacacaaa tggcacgtgc agcaggtata catttgattg
    36421 tagcgacaca aagaccttct gtggatgtaa ttacaggtat cattaaaaat aatattccat
    36481 ctagaatagc ttttgctgtg agttctcaaa cagattcaag aactattatt ggtactggcg
    36541 gcgcagaaaa gttacttggt aaaggtgaca tgttatacgt tggaaatggt gactcatcac
    36601 aaacacgtat tcaaggggcg tttttaagtg accaagaggt gcaagatgtt gtaaattatg
    36661 tagtagaaca acaacaggca aattatgtaa aagaaatgga accagatgca ccagtggata
    36721 aatcggaaat gaaaagtgaa gatgctttat atgatgaagc gtatttgttt gttgttgaac
    36781 aacaaaaggc aagtacatca ttgttacaac gccaatttag aattggttat aatagagcat
    36841 ctaggttgat ggatgattta gaacgcaatc aggtaatcgg tccacaaaaa ggaagcaagc
    36901 ctagacaagt tttaatagat cttaataatg acgaggtgta aaaaaatgtc agaaatgaat
    36961 gcggtatata acgttaaaca atacatttta aatttgatta agcaaaataa attggaatat
    37021 ggtgaccaac ttccaagtaa tttatcaatt gccagagaat taaatgtaaa aaccgacgat
    37081 gtttatgaag caattcaggc attgattact gaacaagtca ttaaagataa ttttgaagag
    37141 ggcacaagtg ttaagtcact gccccctttc ttttatccat tgaatgaact tataagtatt
    37201 gggcaaatga ttaaaaatgc aggatttgaa tgcggaactg aatacttaaa ttttgatgag
    37261 caaccagcaa ctatgttaga tgcaaatttg ttgagcgttg aagaaggata tccagtaacc
    37321 attatagaac gattacgaac tgccgatgga gaaccggtcg tctattgttt agataaaatt
    37381 gctaaaaaag aattaacatg tacagagtat caaatgagca atggatcgat tctaagtgcg
    37441 ataaaagaac aaagtaatca taatatttgt tatgctgata cagaaattga agcggtaaat
    37501 tatgaacctc gaatatccga agtactgaat gcttcgccac acgaaggttt gattttatta
    37561 aaaattacgc actataatga atcagatgaa cctattttgt attcattaaa ttatatgaaa
    37621 aatagcttag ttcaatttaa aatcactaga aaaatataga tgtaagaaga tatagaggag
    37681 gctatatatt tgagtagaca atctcaacca aatatacata tcaaagtttc accaacaact
    37741 aaatttaaaa caactactat agtttttaaa tttatggcac ctttagaata tgacacaata
    37801 acagctagat cattattaag caaattatta gttcgagcaa ctaagaaatg gccaaccgat
    37861 aagtcgttta ataatcactt agccgattta tatggtgcgt atgtgaatag tacaatttca
    37921 aaattcaaag atcagcatgt cattacattt tcattagaaa ttgttaatga acgttattta
    37981 agaaacggtg aatcattatt taatcaagga ttagatttat tacacgaaat catttggaat
    38041 ccattaattg aaaataaagc attcaatgat aattttgtta accaagagaa aacattatta
    38101 gccaaaaaaa tagaagcaat ggtagataat aaagcacaat attcgttttt aaaattactc
    38161 gaccatatgt ttgaaaatga agcatataaa tacttatcta caggacaact agaacaaatc
    38221 ccacatatta ctgctgaaac actatatcat acatatcaat caatgattaa taatgatcaa
    38281 tgttctgttt atgttgtcgg caatgtagaa cctgaaagtg ttgagaaaca aatacgtgaa
    38341 aaatttgcac ttaaaccatt cgataaacat caattccaac attctactca tcatttacac
    38401 gatgaagaag ttgattatat tgttgaatat gatgacgtgg atcaagctaa attaaatatg
    38461 ggataccgtt ttccaacaca atatggacaa agtggatatg ctgcctttgt tgtatttaac
    38521 atgatgtttg gaggagatcc ttcatctgtt ttatttaatg aagtgcgaga aaagcaaagt
    38581 ttagcgtact ctatacattc acaaattgat ggcaaaaatg gctatttatt tgttttgagt
    38641 ggagtttcaa gtgataagta cgaaactgca aaagatacta ttataagtga atttgaaaaa
    38701 ataaaagcag gagatttcac tgaagaaaaa ttagagttag ctaaaaaagt aatcatttct
    38761 catcgatatg aatctgaaga tcgtccgaaa agtattatag agattatgca taaccaaata
    38821 ttattagagc aaccacaaag caaagaaaca tttataaatg atatacagaa ggtaagtcgc
    38881 gaagatattg ttactgttgc tgaaaaagca tttttagata caatctatgt gttgacaaaa
    38941 ggaggggata aataatgaaa gagcgttatt atgaattaat agacgaaaga gtattcgaac
    39001 aagaattaga aaatggttta cgattattta ttatccccaa accaggtttt caaaagacat
    39061 ttgtcactta cactacacaa tttggttcat tagataatca attcaaaccc ctcggacaag
    39121 accaatttgt tactgtacct gatggagttg ctcacttttt agaacataaa ttatttgaaa
    39181 aagaagaaga agacttattt actgcgtttg ctgaagataa tgcacaagca aatgcgttta
    39241 caagctttga tcgtacaagc tacttgttca gtgcaactga taatattgaa aacaacatta
    39301 aacgtttact tacaatggtt gaaacgcctt attttacaaa agaaactgtt gataaagaaa
    39361 aaggtattat tgcagaagaa ataaaaatgt atcaagaaca acctggatat aaattaatgt
    39421 ttaatacatt gcgtgcaatg tatcaacaac atccaatacg tgttgatatt gccggtagtg
    39481 tagaaagtat atacgatatt acaaaagatg atttgtatct atgttatgaa acgttttatc
    39541 atccatcaaa tatggtttta tttgttgttg gtgatgtgaa tccagaagaa atatgtcgaa
    39601 tagtaaaaca gcacgaggat gctcgtaata aagtaaacca acctaaaatc gaacgaggac
    39661 ttgttgatga accggaggat gttaaagaag catttgttac tgaatctatg aaaattcaat
    39721 caccaagact aatgcttggt tttaaaaata aaccattaca agaagcgcct caaaaatatg
    39781 tacaacgtga tttagaaatg tcattattct ttgagttaat ttttggggaa gaaacagatt
    39841 tttatcagaa tttattaaac gaaggactta tcgatgatac atttggttat caatttgtac
    39901 tagagccgac gtatagtttt tcaatcgtga caagcgctac tgaagaacca gataaattaa
    39961 aaaaattatt attagatgag ttgcgtgata aaaaaggcaa tttccaagat gcacaagcat
    40021 ttgaactttt gaaaaagcaa tttataggtg aattcatatc aagtttaaac tcacctgaat
    40081 atattgctaa tcaatatact aaattgtatt ttgaaggtgt tagcgtgttt gacatgttag
    40141 acattgttga aaatatcacg ttagatagta ttaacgaaac gtcatcgtta tatttaaatt
    40201 tagatcagca agtcgatagt cgtttggaga ttaaaaagta atgaaagcat tagtattagg
    40261 tggttctggt tcaattggtt ctgagatagt caaacaatta ttaactgatg gatttgaagt
    40321 ttatgtgcaa tattatcgta ctgatataaa tgaattaact agcaaattta atgatgataa
    40381 agttcatttt atacaaacgg atttatctca aacaactgat attgacaaaa catttggtga
    40441 cattaaatca ttagactgtt taatatatgc aagtggtcag tctttatatg gtgttttaca
    40501 agatatgaaa gaccatgata ttgatgcatg ttatcagtta aatgtcttgc aattaattcg
    40561 attatgtaga tatttcgttg atgttttacg tcaaagtgac aatggaagaa ttattgtaat
    40621 ttcatcaatt tggggtgaga caggagctag tatggaaact atttattcga cgatgaaaag
    40681 tgcacaatta ggtttcgtta aggcgcttag tcaagagctt gcactaacat cagtgacagt
    40741 aaatgctatc gcacctggat ttgtagccgg taatatggca agtgagtggc aagaagatga
    40801 acttcaagca atgataactg aattaccaca acagcgattg gttttaccga gtgaggttgc
    40861 tcatacatgc gcctatttat atcacccaaa tgctagaagt gttactggaa ctatacagaa
    40921 agttaatggt gcttggtata tataaaatat ataactattt ttatgagcaa atgtttttat
    40981 gattgatgtt ataatatgaa tattacaatg aatcataatt tgttaattaa acaaggggtg
    41041 aggttcacca tgacagttgc agagaaaaaa gaatggtacc tagaatacga aattgaaatt
    41101 aatagaccgg gtcttttagg tgatgtatct agtttattag gtatgttagg tataagtatt
    41161 gttacaatta atggtgttga tcaaggtaaa cgaggccttt taattaaaac tgacaatctt
    41221 gaaaaagttg aacgttttga gcaaatagct cgtggtataa atgaaattga aataacaaag
    41281 cttaaaaaac cagaattaag agaccgtctt gcagttagac atggtagata tattgagcaa
    41341 gatgcaaaag ataagaaaac ctttcgattt gagcgtgaag atttaggttt gttagtagac
    41401 tttttagctg aattgttcaa agaagaaggt cataagttga ttggcattag aggtatgcca
    41461 cgggttggta aaactgaatc aattgttgcg ggaagtgttt gtgcacataa gagatggtta
    41521 tttattagtt ctactttaat aaaacaaact gtacgtagct ctctaattaa aggggaatat
    41581 gatgccaatc atgtatacat tattgatggt gcagttactg ccagagaatc taatccaaaa
    41641 catcaagagc ttgttaacga agttatgacg ttaccatcaa tcaaagtcgt tgaacatcca
    41701 gatttatttg ttgaaacaag tacttgtaca atggaagatt ttgactatat tatcgaattg
    41761 agagaaaatg aaaatcaaga aatacattac gaagaaatga agaaacagac agtccaaagt
    41821 aagaataatt tagattttgg agatccattt ggtggtggtt ttggtttctt cgagtaagtg
    41881 taaggaggct atgaattgaa aacggtcggt gaagcgctaa aaggtagacg tgaaaggtta
    41941 ggaatgactt taacagaatt agagcaacgt actggaatta aacgtgaaat gctagtgcat
    42001 attgaaaata atgaattcga tcaactaccg aataaaaatt acagcgaagg atttattaga
    42061 aaatatgcaa gcgtagtaaa tattgaacct aaccaattaa ttcaagctca tcaagatgaa
    42121 attccatcga accaagccga atgggacgaa gtaattacag ttttcaataa taataaagat
    42181 ttagattata agagtaaatc aaaagagcca atacaattat tagtaatcat gggtattaca
    42241 gttttaataa ctttattgtt atggatcatg ttagttttaa tattttaaca gaaataaatt
    42301 agtgagaaat gaggatgtat aatgaatatt ccgaaccaga ttacggtttt tagagtagtg
    42361 ttaataccag tttttatatt gtttgcgtta gttgattttg gatttggcaa tgtgtcattt
    42421 ctaggaggat atgaaataag aattgagtta ttaatcagtg gttttatttt tatattggct
    42481 tcccttagcg attttgttga tggttattta gctagaaaat ggaatttagt tacaaatatg
    42541 gggaaatttt tggatccatt agcggataaa ttattagttg caagtgcttt aattgtactt
    42601 gtgcaactag gactaacaaa ttctgtagta gcaatcatta ttattgccag agaatttgcc
    42661 gtaactggtt tacgtttact acaaattgaa caaggattcg taagtgcagc tggtcaatta
    42721 ggtaaaatta aaacagcagt tactatggta gcaattactt ggttgttatt aggtgatcca
    42781 ttagcaacat tgattggttt gtcattagga caaattttat tatacattgg cgttattttt
    42841 actatcttat ctggtattga atacttttat aaaggtagag atgtttttaa acaaaaataa
    42901 atatttgttt atactagatt tcattttcat atggaatcta gtttttttaa tcccaatttt
    42961 agaaattagc cacgcaattg tttataatga tatattgtaa aacgatattt gttcattttt
    43021 taggcaaatg tgttgtagca tctgatacat tgaatctaaa attgatgtga atttttaaat
    43081 gaaatacatg aaaaaatgaa ttaaacgata caagggggat ataaatgtca attgccatta
    43141 ttgctgtagg ctcagaacta ttgctaggtc aaatcgctaa taccaacgga caatttctat
    43201 ctaaagtatt taatgaaatt ggacaaaatg tattagaaca taaagttatt ggagataata
    43261 aaaaacgttt agaatcaagt gtacgtcatg cgttagaaaa atatgatact gttattttaa
    43321 caggtggctt aggtcctacg aaagatgact taacgaagca tacagtggcc cagattgttg
    43381 gtaaagattt agttattgat gagccttctt taaaatatat tgaaagctat tttgaggaac
    43441 aaggacaaga aatgacacct aataataaac aacaggcttt agtaattgaa ggttcaactg
    43501 tattagcaaa tcatcatggc atggctccag gaatgatggt gaattttgaa aacaaacaaa
    43561 ttattttatt accaggtcca ccgaaagaaa tgcaaccaat ggtgaaaaat gaattgttgt
    43621 cacattttat aaaccataat cgaattatac attctgaact attaagattt gcgggaatag
    43681 gtgaatctaa agtagaaaca atattaatag atcttatcga taaacagact aatcctacga
    43741 ttgcgccttt ggcgggaagt catgaagtat atattagatt gactgcaaat gccgactcaa
    43801 aagaacaagc acaatcattg attcaacctg ttaaacaaga aattcttgat cgtattggag
    43861 aatattatta tggttcagat gacacattaa ttgagcaagc tgtaataaag aaaattcatg
    43921 aaccttttgt aatatatgat ggtattacta atggtgcttt atatcatcga ttgaaagaag
    43981 tggatttaaa cgatgttcta aagggtatga ttaatcacaa tgaaaacttt gttgatatta
    44041 ataaacctat tgagcagcaa ttaaaagatg cagtgcaatt tgttaataaa ttgtttaatg
    44101 tgtcatcagc aattattcta ttagagtatg atggtgtagt ccatataggc tatgataata
    44161 actttgaatt taaaactgag caatttaaaa tgtctaaatc tagaaattta ttaaagaaca
    44221 gaagtcaaaa ttatgcgctc ataagattat taaattggct tagaacaaca aattaattgt
    44281 attatcgata aaaatataag cacgtttgtt cgtttttgcg ttttgatttc aagattttat
    44341 acgaacaaat attcgcaaaa cacttgtatt ttattttgaa tccttgtata gtattggtaa
    44401 gataattaaa agatagcaat ttcaattagg aggtctcgct ttggataacg atcgtcaaaa
    44461 agctttagat acagtaatta aaaatatgga gaaatctttc ggtaaaggtg ccgtaatgaa
    44521 gttgggtgac aatataggtc gccgagtttc aactacatca actggttcag ttacattaga
    44581 taatgcgcta ggtgtaggtg gctatcctaa aggacgaatt attgaaattt atggtcctga
    44641 aagttctggt aagacaacag tagcgcttca cgctattgct gaagtacaaa gtaatggcgg
    44701 ggtggcagca tttatcgatg ctgaacatgc tttagatcca gaatatgctc aagcattagg
    44761 cgtggatatc gataatttat atttatcgca accggatcat ggtgaacaag gtcttgaaat
    44821 cgccgaagca tttgttagaa gtggtgcagt tgatattgta gttgtagact cagttgctgc
    44881 tttaacacct aaagctgaaa ttgaaggaga aatgggagac actcacgttg gtttacaagc
    44941 tcgtttaatg tcacaagcgt tacgtaaact ttcaggtgct atttctaaat caaatacaac
    45001 tgctattttc atcaaccaaa ttcgtgaaaa agttggtgtt atgttcggta atccagagac
    45061 tacaccaggt ggacgtgcat taaaattcta tagttcagta agactagaag tacgtcgtgc
    45121 agaacagctt aaacaaggac aagaaattgt aggtaataga actaaaatta aagtcgttaa
    45181 aaataaagtg gcaccaccat ttagagtagc tgaagttgat attatgtatg gacaaggtat
    45241 ttctaaagag ggtgaactta ttgatttagg tgttgaaaac gacatcgttg ataaatcagg
    45301 agcatggtat tcttacaatg gcgaacgaat gggtcaaggt aaggaaaatg ttaaaatgta
    45361 cttgaaagaa aatccacaaa ttaaagaaga aattgatcgt aaattgagag aaaaattagg
    45421 tatatctgat ggtgatgttg aagaaacaga agatacacca aagtcattat ttgacgaaga
    45481 atagtacaca aatttatatc tatagttaaa cttagcaaat atccttatag gattgattga
    45541 aagtgatatt catctcataa agctagaata atatctaact ttatgggatg cactacaaat
    45601 cgagactata aggtttttta ttttatttat tattacatta tcaatagttt tataatcgag
    45661 cttcaaaact ttagaaaata gtagaaatag cattcaatat agtgcaaaag tgcaaattga
    45721 taacttgaca cttatctcct ataaaccgta caattaattt gtatgattta tatataattt
    45781 cataaagtca tattgaattt catataaaga gcaaacccta gaaaaggagg tgtttgtgtg
    45841 aatttattaa gcctcctact cattttgctg gggatcattc taggagttgt tggagggtat
    45901 gttgttgccc gaaatttgtt gcttcaaaag caatcacaag ctagacaaac tgccgaagat
    45961 attgtaaatc aagcacataa agaagctgac aatatcaaaa aagagaaatt acttgaggca
    46021 aaagaagaaa accaaatcct aagagaacaa actgaagcag aactacgaga aagacgtagc
    46081 gaacttcaaa gacaagaaac ccgacttctt caaaaagaag aaaacttaga gcgtaaatct
    46141 gatctattag ataaaaaaga tgagatttta gagcaaaaag aatcaaaaat tgaagaaaaa
    46201 caacaacaag tagatgcaaa agagagtagt gttcaaacgt taataatgaa gcatgaacaa
    46261 gaattagaac gcatctccgg tctcactcaa gaagaagcta ttaatgagca acttcaaaga
    46321 gtagaggaag aactgtcaca agatattgca gtacttgtta aagaaaaaga aaaagaagct
    46381 aaagaaaaag ttgataaaac agcaaaagaa ttattagcta cagcagtaca aagattagca
    46441 gcagatcaca caagtgaatc aacggtatca gtagttaact tacctaatga tgagatgaaa
    46501 ggtcgaatca ttggacgaga aggacgaaac atccgcacac ttgaaacttt aactggcatt
    46561 gatttaatta ttgatgacac accagaagcg gttatattat ctggttttga tccaataaga
    46621 agagaaattg ctagaacagc acttgttaac ttagtatctg atggacgtat tcatccaggt
    46681 agaattgaag atatggtcga aaaagctaga aaagaagtag acgatattat tagagaagca
    46741 ggtgaacaag ctacatttga agtaaacgca cataatatgc atcctgactt agtaaaaatt
    46801 gtagggcgtt taaactatcg tacaagttac ggtcaaaatg tacttaaaca ttcaattgaa
    46861 gttgcgcatc ttgctagtat gttagctgct gagctaggcg aagatgagac attagcgaaa
    46921 cgagctggac ttttacatga tgttggtaaa gcaattgatc atgaagtaga aggtagtcat
    46981 gttgaaatcg gtgtagaatt agcgaaaaaa tatggtgaaa atgaaacagt tattaatgca
    47041 atccattctc atcatggtga tgttgaacct acatctatta tatctatcct tgttgctgct
    47101 gcagatgcat tgtctgcggc tcgtccaggt gcaagaaaag aaacattaga gaattatatt
    47161 cgtcgattag aacgtttaga aacgttatca gaaagttatg atggtgtaga aaaagcattt
    47221 gcgattcagg caggtagaga aatccgagtg attgtatctc ctgaagaaat tgatgattta
    47281 aaatcttatc gattggctag agatattaaa aatcagattg aagatgaatt acaatatcct
    47341 ggtcatatca aggtgacagt tgttcgagag actagagcag tagaatatgc gaaataattt
    47401 ttgtctccct cacaaattag tgagggagct tttttaagtt gtagtctcaa tctagttaga
    47461 cagcacttta ttggtaataa ctatattaaa cagtagttat ttgaaagtaa gtcggaccgt
    47521 atataaaata agaagttatt gcttttaata aaaatgtttt aggcttcata attactatat
    47581 ttatattatg taaacctata aagatgattg cttttctatc caataaaaaa gaggctggaa
    47641 cattaagttc ttaggcaatg taaaaaagct gatttctatt aattatttga tagaaatcag
    47701 cttttctgat atgtatttta taatgtacag ctcgttgagc tgctattttt cttatattaa
    47761 gtgccgttaa tacaaaacct aggtctcgtt taactttatt tattcctcga actgacattc
    47821 gagtgaaacc caaaatagcc ttcataaatc caacaacaga ctctacaaca atttttcttt
    47881 gactatagat ttttttcgtt tctggttcag aaagcttttg attaacttgg gctttaaagt
    47941 attcacaatt ataattcttc ataattttct tattggattt tgaatttggc ttcatgcatt
    48001 gatgtctcaa agaacatgct gaacagtcat cacattcata tagtttgaag tcacgtttaa
    48061 aaccatatct atgattacgg tatgcatatc ttctaaaacc tattcttttg ttattaggac
    48121 atataaattc atcattaagt tcgtcatatt tccaattttg agtgttgaaa atgtcacctt
    48181 taaactttct agttttatct ttaataaaca tgccatacgt aataagtggc gctttattaa
    48241 aagtcatcta taatagccat atagttttgc tcactaccat aacctgcatc agctacaata
    48301 tactctggta aataaccgaa ggtattttga atcattgtta aaaatggaat taaagttcta
    48361 gtatctgttg ggttttgaaa taggtcatag gataaaacaa attgagaatt tgtcgctatt
    48421 tgtaaattgt atcctggctt aagttggcca tttttcatat ggtcttcctt cattctcata
    48481 aaagttgcat aatgatcagt tttagaaaag ctatttttat cttctttaat ctctggtatt
    48541 atttttcttc aactaagtca cgatatagtg tttttgaatt ctcgttcaat ttcgatttgt
    48601 tattttgaat acttttttcc acaccaatgt atatctattg gtagtgtaag ttgg
//
LOCUS       DAPSKH010000013        42969 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPSKH010000013 DAPSKH010000000
VERSION     DAPSKH010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 42969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42969
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.013"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            5..994
                     /gene="ccpA"
                     /locus_tag="RPH49_000839"
     CDS             5..994
                     /gene="ccpA"
                     /locus_tag="RPH49_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDY5124024.1"
                     /translation="MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRL
                     NYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLARGLEDIATMYKYHSIISNSDNDP
                     EKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
                     FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSG
                     AESYKEGVKAFAKMKGNLPDAILCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRL
                     VEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPHRIEYRGTTK"
     gene            complement(1092..2261)
                     /locus_tag="RPH49_000840"
     CDS             complement(1092..2261)
                     /locus_tag="RPH49_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin utilization protein AcuC"
                     /protein_id="HDY5124025.1"
                     /translation="MQQHSSKTAYVYSDKLLQYRFHDQHPFNQMRLKLTTELLLNANL
                     LSPEQIVQPRIATDDELMLIHKYDYVEAIKHASHGIISEDEAKKYGLNDEENGQFKHM
                     HRHSATIVGGALTLADLIMSGKVLNGCHLGGGLHHAQPGRASGFCIYNDIAITAQYLA
                     KEYNQRVLIIDTDAHHGDGTQWSFYADNHVTTYSIHETGKFLFPGSGHYTERGEDIGY
                     GHTVNVPLEPYTEDASFLECFKLTVEPVIKSFKPDIILSVNGVDIHYRDPLTHLNCTL
                     HSLYEIPYFVKYLADSYTNGKVIMFGGGGYNIWRVVPRAWSHVFLSLIDQPIQSGYLP
                     LEWINKWKHYSSELLPKRWEDRLNDYTYVPRTKEISEKNKKLALHIASWYESTRQ"
     gene            complement(2286..2918)
                     /locus_tag="RPH49_000841"
     CDS             complement(2286..2918)
                     /locus_tag="RPH49_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124026.1"
                     /translation="MNHLKTYQSEDYYIHDKQFVIEGPLTYEDLKALTFDAHLTAFRD
                     AEDQYEALLEITTLPEGRIYVARQDQLIVGYVTFHYPDEIERWSTGNLPYLIELGAIE
                     VSINFRQLQLAEKLIQLSLSTPEFEDYIVITTEYYWHWDLKNSKLDVFDYKKLMQRLM
                     ATGGLEIFATDDPEITSHPANCLMARIGKNITLEQQQAFDDIRYMNRFFF"
     gene            3087..4793
                     /gene="acsA"
                     /locus_tag="RPH49_000842"
     CDS             3087..4793
                     /gene="acsA"
                     /locus_tag="RPH49_000842"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDY5124027.1"
                     /translation="MKVEVYKGAQGKHNLKDYEETYNTFNWKDVEQAFSWSETGKMNM
                     AYECIDRHVDQGIGDKIALNYKDEHRKESYTYKDMQRLSNKAANVLSEHAEVDKGDRV
                     FIFMSRTPELYFALLGVLKIGAIVGPLFEAFMEKAVVDRLENSEAKVLITNKALLPRV
                     PVDKLPNLKKIVVVDEDVEDNYIDFISLMETASDEFDIEWLKSDDGLILHYTSGSTGQ
                     PKGVLHVQQAMLVHYISGKYVLDLQEDDVYWCTADPGWVTGTSYGIFAPWLNGATNCI
                     AGGRFSPEQWYSMIEDFKVTIWYTAPTALRMLMSAGDDIVEKYDLSSLRSILSVGEPL
                     NPEVIKWAKKVYGLTVLDTWWMTETGGHMIVNYPTMDVKLGSMGKPLPGIQAAIIDDA
                     GNELPPNRMGNLAIKKGWPSMMYRIWKNPEKYKSYFIGDWYVSGDSAYKDEDGYFWFQ
                     GRVDDVIMTAGERVGPFEVESKLVEHEAVAEAGIIGKPDPVRGEIIKAFVALRKGYEP
                     TDELKEEIRLFVKEGLSAHAAPREIEFKDKLPKTRSGKIMRRVLKAWELNLDAGDLST
                     ME"
     gene            5233..6900
                     /locus_tag="RPH49_000843"
     CDS             5233..6900
                     /locus_tag="RPH49_000843"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDY5124028.1"
                     /translation="MTHLSDLDIANQSTLQPIKDIAASVGISEDALEPYGHYKAKIDI
                     NKITPRENKGRVVLVTAMSPTPAGEGKSTVTVGLADAFHELNKNVMVALREPALGPTF
                     GIKGGATGGGYAQVLPMEDINLHFNGDFHAITTANNALSAFIDNHIHQGNELGIDQRR
                     IEWKRVLDMNDRALRHVNVGLGGPTNGVPREDGFNITVASEIMAILCLSRSIKDLKDK
                     ISRITIGYTRNRKPVTVADLKVQGALAMILKDAIKPNLVQSIERTPALVHGGPFANIA
                     HGCNSILATETARDLADIVVTEAGFGSDLGAEKFMDIKAREAGFDPAAVVVVATIRAL
                     KMHGGVAKDNLKEENVEAVKAGIVNLERHVNNIKKFGVEPVVAINAFIHDTDAEVEYV
                     KSWAKENNVRIALTEVWEKGGKGGVDLANEVLEVIDQPNSFKPLYELELPLEQKIEKI
                     VTEIYGGSKVTFSSKAHKQLKQFKENGWDNYPVCMAKTQYSFSDDQTLLGAPSGFEIT
                     IRELEAKTGAGFIVALTGAIMTMPGLPKKPAALNMDVTDDGHAIGLF"
     gene            complement(7145..7234)
                     /locus_tag="RPH49_000844"
     CDS             complement(7145..7234)
                     /locus_tag="RPH49_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124029.1"
                     /translation="MLLTTPIRLYLIDNNYQYQLLVLIVAHPN"
     gene            7233..9920
                     /gene="harA"
                     /locus_tag="RPH49_000845"
     CDS             7233..9920
                     /gene="harA"
                     /locus_tag="RPH49_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haptoglobin-binding heme uptake protein HarA"
                     /protein_id="HDY5124030.1"
                     /translation="MNKHHPKLRSFYSIRKSTLGVASVIVSTLFLITSQHQAQAAENT
                     NTSDKISENQNNNATTTQPPKDTNQTQPATQPANTAKNYPAADESLKDAIKDPALENK
                     EHDIGPREQVNFQLLDKNNETQYYHFFSIKDPADVYYTKKKAEVELDINTASTWKKFE
                     VYENNQKLPVRLVSYSPVPEDHAYIRFPVSDGTQELKIVSSTQIDDGEETNYDYTKLV
                     FAKPIYNDPSLVKSDKNDAVVTNDQSSSDASNQTNTNTSNQNTSTTNNTSDQPYATTN
                     MSQPAQPVSSANADQASSQPAHETNSNGNTNDKTNESSNQSDVNQQYPPADESLQDAI
                     KNPAIIDKEHTADNWRPIDFQMKNDKGERQFYHYASTVEPATVIFTKTGPIIELGLKT
                     ASTWKKFEVYEGDKKLPVELVSYDSDKDYAYIRFPVSNGTREVKIVSSIEYGENIHED
                     YDYTLMVFAQPITNNPDDYVDEETYNLQKLLAPYHKAKTLERQVYELEKLQEKLPEKY
                     KAEYKKKLDQTRVELADQVKSAVTEFENVTPTNDQLTDLQEAHFVVFESEENSESVMD
                     GFVEHPFYTATLNGQKYVVMKTKDDSYWKDLIVEGKRVTTVSKDPKNNSRTLIFPYIP
                     DKAVYNAIVKVVVANIGYEGQYHVRIINQDIKTKDDATSQNNTSEPLNVQTGQEGKVA
                     DTDVAENSSTATNPKDASDKADVIEPESDVVKDADNNIDKDVQHDVDHLSDMSDNNHF
                     DKYDLKEMDTQIAKDTDRNVDKDADNSVGMSSNVDTDKDSNKNKDKVIQLNHIADKNN
                     HTGKAAKLDVVKQNYNNTDKVTDKKTTEHLPNDIHKTVDKTVKTKEKAGTPSKENKLS
                     QSKMLPKTGETTSSQSWWGLYALLGMLALFIPKFRKESK"
     gene            10051..10143
                     /locus_tag="RPH49_000846"
     CDS             10051..10143
                     /locus_tag="RPH49_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124031.1"
                     /translation="MKIILLLFLIFGFIVVVTLKSEHQLTLFSI"
     gene            complement(10123..11028)
                     /locus_tag="RPH49_000847"
     CDS             complement(10123..11028)
                     /locus_tag="RPH49_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDY5124032.1"
                     /translation="MTNQDNNHQLNHRIYHFEKIYKAIKHVIVFIFMIFIAIVAIAVI
                     AMSLYFHHLTKTSDSLSDDALIKKVRQIPGDELLDHNNKNLLYEYNHSQNSLIIGPKT
                     SSPNVIKALTSSEDTLFYKHDGILPKAILRAMIQDIFNTDQSSGGSTITQQLVKNQVL
                     TNEKTYSRKANELRLAIRLEHLLSKDEIIYTYLNIVPFGRDYNGANISGIASASYSLF
                     GIPPKDLSIAQSAYLIGLLQSPYGYTPYEKDGTLKSDKDLKYSIQRQHYVLKRMLIED
                     QITEKEYNDALKYDIKSHLLNRKKR"
     gene            11409..12671
                     /locus_tag="RPH49_000848"
     CDS             11409..12671
                     /locus_tag="RPH49_000848"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDY5124033.1"
                     /translation="MTNVLIEDLKWRGLIYQQTDEQGIEDLLNKEQVTLYCGADPTAD
                     SLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEG
                     ISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLRDYGKHVGVNYMLGKDSIQSRLE
                     HGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWGNITSGIELMRRMYGQTDAYG
                     LTIPLVTKSDGKKFGKSESGAVWLDAEKISPYEFYQFWINQSDEDVIKFLKYFTFLGK
                     EEVDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAIRISQALFSGDLKSLSAK
                     ELKDGFKDVPQVTLSNDTTNIVEVLIETGISPSKRQAREDVNNGAIYINGERQQDVNY
                     ALAPEDKIDGEFTIIRRGKKKYFMVNYQ"
     gene            complement(12765..14039)
                     /locus_tag="RPH49_000849"
     CDS             complement(12765..14039)
                     /locus_tag="RPH49_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDY5124034.1"
                     /translation="MSDFNHTDHSTTNHSQTPRYRRPKFPWFKTVIVALIAGIIGALL
                     VLGIGKVLNSTILNKDGSTVQTTNNKGGNQLDGQSKKFGTVHEMIKSVSPTIVGVINM
                     QKASSVDDLLKGKSSKPSEAGVGSGVIYQINNNSAYIVTNNHVIDGANEIRVQLHNKK
                     QVKAKLVGKDAVTDIAVLKIENTKGIKAIQFANSSKVQTGDSVFAMGNPLGLQFANSV
                     TSGIISASERTIDAETTGGNTKVSVLQTDAAINPGNSGGALVDINGNLVGINSMKIAA
                     TQVEGIGFAIPSNEVKVTIEQLVKHGKIDRPSIGIGLINLKDIPEEEREQLHTDREDG
                     IYVAKADSDIDLKKGDIITEIDGKKIKDDVDLRSYLYENKKPGESVTVTVIRDGKTKE
                     VKVKLKQQKEQPKRQSRSERQSPGQGDRDFFR"
     gene            14211..14828
                     /locus_tag="RPH49_000850"
     CDS             14211..14828
                     /locus_tag="RPH49_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDY5124035.1"
                     /translation="MYSVISKILNFILVKMSKSLYVIGKDNIPKDSKYVVTCTHESYN
                     EVIMLGMALYPNQIHYMAKKELFKNKWIGKFLTSLNAFPVDRENPGPSTLKRPINLLK
                     DNKTVGIFPTGSRTSQEGAPLKRGASTIAMLSKSPILPVAYVGPTKIHGLLTGQAYIN
                     IGKPIDINDLPKDLKRNERIDYITKEIETRTAKLQQELHEIVKSL"
     gene            14956..16422
                     /locus_tag="RPH49_000851"
     CDS             14956..16422
                     /locus_tag="RPH49_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIBC"
                     /protein_id="HDY5124036.1"
                     /translation="MYKFFQNLGRSLMLPVAILPAAAIIAGIGNTLNALHATPKIAMF
                     FTTVGTTILEQLGILFAIGVAIGMAKKNDGAVALAATLGYFLVTVVLSPMKLAPLLGM
                     KASEINSAFEKMNNGNVFVGIVIGLIAAYAYNKFSETELPLALSFFSGKRLVPIMTAF
                     YCTFLVVILLFLWPLLYSWIVKFGESIVGLGSFGAFIYGVANRLLIPTGLHHALNSVF
                     WFDTIGINDIGKFQSGKDAIKGITGRYQAGFFPIMMFGIPAAALAMYHTAKTTQKKQV
                     YGWFLASSVAAFFVGVTEPIEFAFMFVAPILYVVHALLTGLSLFIAATFHWTAGFSFS
                     AGLIDYVLSLINPVSNHPLMLLVQGVVFFILYYVIFRVVIQVFNLNTIGRGENELVDP
                     TVVKDNIAPGENDIKQSKYHQHAIQILEGLGGQENIVNLTNCATRLRLELKDTSIIDQ
                     QKIKNAGAVGVTVNGKHSTQVIVGTHVQQVADEIEKHL"
     gene            16529..17659
                     /locus_tag="RPH49_000852"
     CDS             16529..17659
                     /locus_tag="RPH49_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5124037.1"
                     /translation="MKKILFDVDGVFLSEERCFDVSALTVYELLMDKCYLGLHSHIDW
                     ETLTDNDIQDIRNRIFQKDKILNKLKSLGLNSNWDMLFIVFSIHLIDILKKLSHDEIE
                     AFMYQDEPVELKLQNISTNLADCFNLNEQLPLQFLDNVKVGKNNIYAALEEFATTELH
                     VSDATLFSLKGALWTLAQEVYQEWYLGSKLYEDVEKKIARTTFKTGYIYQEIILRPVD
                     EVKVLLNDLKGAGFELGIATGRPYTETVVPFENLGLLPYFEADFIATASDVLEAENMY
                     PQARPLGKPNPFSYIAALYGNNRDKYESYINKQDNIVNKDDVFIVGDSLADLLSAQKI
                     GATFIGTLTGLKGKDAAGELEAHHADYVINHLGELRGVLDNL"
     gene            complement(17620..17715)
                     /locus_tag="RPH49_000853"
     CDS             complement(17620..17715)
                     /locus_tag="RPH49_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124038.1"
                     /translation="MKPLVQSFTSSCAVKQQSNYKLSSTPLSSPK"
     gene            complement(17809..19413)
                     /locus_tag="RPH49_000854"
     CDS             complement(17809..19413)
                     /locus_tag="RPH49_000854"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDY5124039.1"
                     /translation="MKQFNVLVADPISKDGIKALLDHEKFNVDIQTGLSEEALIKIIP
                     SYHALIVRSQTTVTENIINAADSLKVIARAGVGVDNINIDAATLKGILVINAPDGNTI
                     SATEHSLAMLLSMARNIPQAHQSLTNKEWNRNAFKGTELYHKTLGVIGAGRIGLGVAK
                     RAQSFGMKILAFDPYLTDEKAKSLSITKATVDEIAQHSDFVTLHTPLTPKTKGLINAD
                     FFAKAKPSLQIINVARGGIIDEKALIKALDEGQISRAAIDVFEHEPATDSPLVAHDKI
                     IVTPHLGASTVEAQEKVAISVSNEIIEILIDGTVTHAVNAPKMDLSNIDDTVKSFINL
                     SQTVGELAIQLMYNAPSSIKITYGGDLASIDSSLLTRTIITHILKDDLGPEVNIINAL
                     MLLNQQQVTLNIENNKAETGFSNYLEVELSNDSDSVKVGASVFTGFGQRIVRINNFSV
                     DLKPNQYQIVSYHNDTPGMVGKTGALLGKYNINIASMTLGRTEAGGDALMILSVDQPV
                     SNNIIDELKQVGEYNQIFTTELTVQS"
     gene            complement(19400..20559)
                     /locus_tag="RPH49_000855"
                     /pseudo
     CDS             complement(19400..20559)
                     /locus_tag="RPH49_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500338.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--glyoxylate aminotransferase family
                     protein"
     gene            complement(20674..21120)
                     /locus_tag="RPH49_000856"
     CDS             complement(20674..21120)
                     /locus_tag="RPH49_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDY5124040.1"
                     /translation="MHQHDFKVQTSWQGGRNNVGNVQGDILSENISIPASLGGVGIGT
                     NPDEMLVSAASSCYIISLAATLERAKFTDISIEQQSIGTACLNNGKFSMSKIVHHPHI
                     EIPSDQIAQLEKRLPKLITIADNNCMISNAVRNNVDIKIYPIIQAK"
     gene            21200..21943
                     /locus_tag="RPH49_000857"
     CDS             21200..21943
                     /locus_tag="RPH49_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDY5124041.1"
                     /translation="MTLNKLKDELQIVSHRGLPSDFPENTMVGYREVMGLNVAMLEID
                     VHLTKDQHFVVIHDETIDRTSDGKGRIADYTLSQLKSFDFGSYKDVAFKGERIPTLDE
                     VLSLCLKYDKKLLIELKSPNLYPEIECKLLAFLEEKKVDATQVVIQSFDIECIEKLNT
                     LGSIYELGVLCSKRKYWYKKPNFSRISQIASYVNPNYALVTRKFVDEAHHHQLQVMPY
                     TVNKLKTGEKLRQMGVDGLITDNPKLFIK"
     gene            complement(22160..22762)
                     /gene="rpsD"
                     /locus_tag="RPH49_000858"
     CDS             complement(22160..22762)
                     /gene="rpsD"
                     /locus_tag="RPH49_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019165370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDY5124042.1"
                     /translation="MARFRGSNWKKSRRLGISLSGTGKELEKRPYAPGQHGPNQRKKL
                     SEYGLQLREKQKLRYLYGMTERQFRNTFDIAGKKFGVHGENFMILLASRLDAVVYSLG
                     LARTRRQARQLVNHGHILVDGKRVDIPSYSVKPGQTISVREKSQKLNIIVESVEINNF
                     VPEYLNFDADSLTGTFVRLPERSELPAEINEQLIVEYYSR"
     gene            complement(23006..23470)
                     /locus_tag="RPH49_000859"
     CDS             complement(23006..23470)
                     /locus_tag="RPH49_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDY5124043.1"
                     /translation="MTTINPTNYALLKKQAASLIEDEHHMIAILSNMSALLNDNLDQI
                     NWVGFYLLEQNELILGPFQGHPACVHIPIGKGVCGTAVSERRTQIVADVHQFEGHIAC
                     DANSKSEIVVPIFKDDKIIGVLDIDAPITDRFDDNDKEHLEAIVKIIEKQLA"
     gene            23607..25301
                     /gene="ezrA"
                     /locus_tag="RPH49_000860"
     CDS             23607..25301
                     /gene="ezrA"
                     /locus_tag="RPH49_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDY5124044.1"
                     /translation="MVLYIILAIIVIILIAVGVLFYLRSNKRQIIEKAIERKNEIETL
                     PFDQNLAQLSKLNLKGETKTKYDAMKKDNVESTNKYLAPVEEKIHNAEALLDKFSFNA
                     AQSEIDDANELMDSYEQSYQQQLEDVNEIIALYKDNDELYDKCKVDYREMKRDVLANR
                     HQFGEAASLLETEIEKFEPRLEQYEVLKADGNYVQAHNHIAALNEQMKQLRSYMEEIP
                     ELIRETQKELPGQFQDLKYGCRDLKVEGYDLDHVKVDSTLQSLKTELSFVEPLISRLE
                     LEEANDKLANINDKLDDMYDLIEHEVKAKNDVEETKDIITDNLFKAKDMNYTLQTEIE
                     YVRENYYINESDAQSVRQFENEIQSLISVYDDILKEMSKSAVRYSEVQDNLQYLEDHV
                     TVINDKQEKLQNHLIQLREDEAEAEDNLLRVQSKKEEVYRRLLASNLTSVPERFIIMK
                     NEIDHEVRDVNEQFSERPIHVKQLKDKVSKIVIQMNTFEDEANDVLVNAVYAEKLIQY
                     GNRYRKDYRNVDKSLNEAERLFKNNRYKRAIEIAEQALESVEPGVTKHIEEEVIKQ"
     gene            complement(25375..25516)
                     /locus_tag="RPH49_000861"
                     /pseudo
     CDS             complement(25375..25516)
                     /locus_tag="RPH49_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500331.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            25666..26814
                     /locus_tag="RPH49_000862"
     CDS             25666..26814
                     /locus_tag="RPH49_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDY5124045.1"
                     /translation="MFILIYLDNAATTKAFEEVLDTYLKVNQSMYYNPNSPHKAGLQA
                     NQLLQQAKAQINAMINSKTNYNVVFTSGATESNNLALKGIAYRKFDTAKEIITSVLEH
                     PSVLEVVRYLEAHEGFKVNYVDVKKDGSINLEHFKELMSDKVGLVTCMYVNNVTGQIQ
                     PIPQMAEVIKNYPKAHFHVDAVQAFGKISMDFNNVDSISLSGHKFNGLKGQGVLLVNH
                     IQNVEPTVHGGGQEYGVRSGTVNLPNDIAMVKAMKIANENFEALNAFVTELNNDVRQF
                     LNKYHGVYINSSTSGSPFVLNISFPGVKGEVLVNAFSKYDIMISTTSACSSKRNKLNE
                     VLAAMGLSDKSIEGSIRLSFGATTTKEDIARFKEIFIIIYEEIKELLK"
     gene            26814..28037
                     /gene="thiI"
                     /locus_tag="RPH49_000863"
     CDS             26814..28037
                     /gene="thiI"
                     /locus_tag="RPH49_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDY5124046.1"
                     /translation="MKYDHLLVRYGELTLKGSNRKKFVNQLRNNVNKSLKGLDGFVVK
                     GKRDRMYIELEDHADINEITYRLSKIFGIKSISPVLKVEKTIEAMSAAAIKFAQQFEE
                     NSTFKIDVKRADKNFPMDTYELQRELGGTVLKQIENVSVNVKRPDHEIRVEVRLDAIY
                     MYEEVVPGSGGLPVGTGGKTLLMLSGGIDSPVAGMEVMRRGVTIEAIHFHSPPFTSDQ
                     AKEKVIELTRILAERVGPIKLHIVPFTELQKQVNKVVHPRYTMTSTRRMMMRVADKLV
                     HQIGALAIVNGENLGQVASQTLHSMYAINNVTSTPVLRPLLTYDKEEIIIKSKEIGTF
                     ETSIQPFEDCCTIFTPKNPVTEPNFDKVVQYESVFDFEEMINRAVENIETLEITSDYK
                     TIKEQQTNQLINDFL"
     gene            28081..28851
                     /locus_tag="RPH49_000864"
     CDS             28081..28851
                     /locus_tag="RPH49_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TSUP family transporter"
                     /protein_id="HDY5124047.1"
                     /translation="MDLNLTMIIIIILFGFIAAFIDSVVGGGGLISTPALLAIGLPPS
                     VALGTNKLASSFGSLTSTIKFIRSGKVDLFVVAKLFGFVFLASACGAYIATMVPSQIL
                     KPLIIIALSSVFIFTLLKKDWGNTRTFTQFTFKKAIIFAALFILIGFYDGFVGGGTGS
                     FMLFVLLIFGFDFLSAAGNAKVLNFASNIGALVLFMVLGQVDYVIGLIMATSMIAGSY
                     TGAHFAIKQGVAYVKVLFIIITAILILKNAFDYIQQFV"
     gene            28949..29443
                     /gene="tpx"
                     /locus_tag="RPH49_000865"
     CDS             28949..29443
                     /gene="tpx"
                     /locus_tag="RPH49_000865"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDY5124048.1"
                     /translation="MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAG
                     KKKLISVVPSIDTGVCDQQTRKFNSEASKEEGIVLTISADLPFAQKRWCASAGLDNVI
                     TLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAA
                     CKII"
     gene            29566..30513
                     /locus_tag="RPH49_000866"
     CDS             29566..30513
                     /locus_tag="RPH49_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5124049.1"
                     /translation="MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTN
                     ERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEE
                     LHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQD
                     AIMPLPLEEADIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINALKDAG
                     YAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSG
                     ETKPVEVLLANIPDFKNPSQFQGFMTELNQWMDTNRPKK"
     gene            30601..31803
                     /locus_tag="RPH49_000867"
     CDS             30601..31803
                     /locus_tag="RPH49_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDY5124050.1"
                     /translation="MSKLILAINAGSSSLKFQLIRMPEEELVTKGLIERIGLKDSIFT
                     IEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESV
                     AITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYL
                     YSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAID
                     GGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGL
                     SGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGEN
                     SVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARD
                     VMTFGGLK"
     gene            complement(32049..32549)
                     /locus_tag="RPH49_000868"
     CDS             complement(32049..32549)
                     /locus_tag="RPH49_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDY5124051.1"
                     /translation="MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSR
                     TYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAH
                     EINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQL
                     REKYQN"
     gene            32690..33808
                     /gene="ald"
                     /locus_tag="RPH49_000869"
     CDS             32690..33808
                     /gene="ald"
                     /locus_tag="RPH49_000869"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HDY5124052.1"
                     /translation="MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSF
                     FEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKL
                     TQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLG
                     GVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIM
                     SNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFET
                     TDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFK
                     SNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL"
     gene            33932..34045
                     /locus_tag="RPH49_000870"
     CDS             33932..34045
                     /locus_tag="RPH49_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124053.1"
                     /translation="MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLGQKFMS"
     gene            complement(34124..35179)
                     /locus_tag="RPH49_000871"
     CDS             complement(34124..35179)
                     /locus_tag="RPH49_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDY5124054.1"
                     /translation="MTKISKIIDELNNRQADAAWITTPLNVYYFTGYRSEPHERLFAL
                     LIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTV
                     ARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEG
                     VTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGV
                     IYEHYCSDMTRTIKFGEPSKETQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIIS
                     EKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPGVAGVRIED
                     DILVTNEGYEVLTHYEK"
     gene            35354..36043
                     /locus_tag="RPH49_000872"
     CDS             35354..36043
                     /locus_tag="RPH49_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDY5124055.1"
                     /translation="MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYI
                     VLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGS
                     VKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPV
                     DVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDV
                     QILKPGESVQF"
     gene            complement(36348..36761)
                     /locus_tag="RPH49_000873"
     CDS             complement(36348..36761)
                     /locus_tag="RPH49_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDY5124056.1"
                     /translation="MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQ
                     ASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEI
                     VVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK"
     gene            36966..38264
                     /locus_tag="RPH49_000874"
     CDS             36966..38264
                     /locus_tag="RPH49_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDY5124057.1"
                     /translation="MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDAD
                     KMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGA
                     MELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPV
                     LSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANR
                     TGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMI
                     WEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGIT
                     VEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHI
                     TVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV"
     gene            38573..39514
                     /gene="pde2"
                     /locus_tag="RPH49_000875"
     CDS             38573..39514
                     /gene="pde2"
                     /locus_tag="RPH49_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pApA hydrolase Pde2"
                     /protein_id="HDY5124058.1"
                     /translation="MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQK
                     FPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLI
                     KIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTG
                     RFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMGDGFC
                     QVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGSEIRCRLRSKGQLIIN
                     DIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN"
     gene            39535..42732
                     /locus_tag="RPH49_000876"
     CDS             39535..42732
                     /locus_tag="RPH49_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDY5124059.1"
                     /translation="MAAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLY
                     GFPKFYDTCIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNAL
                     EHVSFELLKRFSNNMIIIFKNVADEHRDIVQVFDSHEDTYLDHRSVLVQGIKHVWIQN
                     VCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTENEIQQLDVNQEYLTQVDV
                     IAQKCNAELKYHQSLLPQYQTPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYK
                     VITNMGFEDYFLIVSDLIHYAKTHDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLF
                     ERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVG
                     RIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLP
                     RHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSII
                     HQILTQVKKDLGINIDIENIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEH
                     FEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQ
                     IASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILK
                     FADYGFPRAHAVSYSKIAYIMSYLKVRYPNYFYANILSNVIGSEKKTAQMIEEAKKQG
                     ITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFAR
                     RIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPK
                     QMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQ
                     FDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDLR
                     KQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSHIDAFEEAIKATKENANDVVLSFY
                     DETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI"
BASE COUNT        14844 a         6255 c         7879 g        13991 t
ORIGIN      
        1 aattatgaca gttactatat atgatgtagc aagagaagcg cgtgtctcta tggccacagt
       61 gtcgcgtgtt gttaatggga accaaaatgt taaagcagaa actaaaaata aagttaacga
      121 agtcattaag cgtttgaatt atcgtccaaa tgctgttgct agaggtttag ctagtaaaaa
      181 gacaacaaca gtaggtgtga tcattccaga tatatctaat atctattatt cacaacttgc
      241 tcgtggactt gaagatattg caacaatgta taaatatcac tcaattattt caaattcaga
      301 taacgatcct gaaaaggaaa aagaaatttt taataactta ttaagtaaac aagttgatgg
      361 tattattttc cttggtggta caattactga agaaatgaaa gaattgataa atcaatcatc
      421 tgtacctgta gtagtatcag gaacaaatgg taaggatgca catatagcat cagttaatat
      481 tgattttact gaagctgcga aagaaattac gggagaatta attgaaaaag gcgctaaatc
      541 atttgcttta gtaggtggag aacattctaa aaaagctcaa gaagatgttt tagaaggttt
      601 aactgaagtg ttaaataaaa atggtcttca attaggtgat acattgaatt gttctggtgc
      661 tgaaagttat aaagaaggcg taaaagcttt tgccaaaatg aaaggtaatc ttccagatgc
      721 tatattatgt attagtgacg aagaagctat tggtattatg catagtgcaa tggatgctgg
      781 tattaaagtt ccagaggaat tacaaattat tagtttcaat aatacacgtt tagttgagat
      841 ggttagacca caactttcta gtgttattca accattatat gatatcggtg cagtagggat
      901 gcgcttatta acaaaatata tgaatgatga aaagatagaa gaaccaaatg tagttttacc
      961 tcacagaatt gaataccgag gaactacaaa ataaattcac aaaattaggc attcatctaa
     1021 cgacccgaat tatatgggtg ttggaagaat gccttttatt tatcttttaa aatcgttgca
     1081 gattaggtta cttattgacg agtagattcg taccaactcg ctatatgtaa agctaatttt
     1141 ttattttttt cactaatttc ttttgtgcga gggacatagg tataatcatt taaacgatct
     1201 tcccatcttt taggtaataa ttcagatgaa taatgtttcc atttattaat ccattctaac
     1261 ggtaaataac cactttgaat tggttgatca attaaactta agaatacatg actccatgca
     1321 cgtggtacga ctctccaaat attgtagcct ccgccaccaa acataattac ctttccattc
     1381 gtataagaat cagctaaata ttttacaaaa tatggaattt catataatga atgtaacgta
     1441 caatttagat gagttagtgg atcacgataa tgtatatcga caccatttac gcttagaata
     1501 atatcaggtt taaaactctt tatgacaggc tcaactgtta atttaaaaca ctccaaaaat
     1561 gatgcatctt ctgtatacgg ttcaagtggg acatttacag tgtgtccata gccgatatct
     1621 tcaccgcgct cagtatagtg accagagcct gggaaaagaa attttccagt ttcatggata
     1681 gaataagtag taacatggtt atcggcatag aaactccatt gtgtaccatc tccatgatgt
     1741 gcatcggtat ctatgattaa aacgcgttga ttgtattctt tagctaagta ttgtgcggta
     1801 attgcaatat cattgtatat acaaaaacca cttgctcgac caggttgagc gtgatgcaat
     1861 ccaccaccta agtgacaacc atttaatact ttgcctgaca taataagatc tgctaaagtt
     1921 aaagcgcctc caacaattgt ggcgctatgg cggtgcatat gcttaaattg accattctct
     1981 tcatcattta atccatattt cttagcctca tcttcactga taatgccatg tgaagcatgc
     2041 ttaatagctt cgacgtaatc atatttatga attaacatta attcgtcatc tgttgcaatt
     2101 ctaggttgta ctatttgttc aggagacaat aaatttgcat tcaaaagtag ctctgttgtt
     2161 aattttaaac gcatttgatt gaagggatgt tggtcatgaa atcgatattg taataactta
     2221 tctgaataaa catatgcagt ttttgatgaa tgttgttgca tataatccct ccgatattcc
     2281 aaaaattaaa agaaaaaccg attcatataa cgaatatcat caaacgcttg ttgctgttct
     2341 aatgtaatgt ttttgccaat tcttgccatt aaacaattag ctggatgact tgttatttct
     2401 ggatcatctg tagcgaatat ttcaagtcca ccagttgcca ttaaccgctg cattaatttt
     2461 ttatagtcaa atacatctaa ctttgaattt tttaaatccc aatgccagta atattctgta
     2521 gttataacga tataatcctc gaattctggt gtagaaaggc taagttgtat cagcttttct
     2581 gcaagttgta attgcctaaa attgatgctg acttcaattg cccccaattc gattaaatat
     2641 ggaaggttac ctgtagacca gcgctcaatt tcatcaggat agtggaaagt gacataaccc
     2701 acaatgagtt gatcttggcg agcaacataa attctacctt ctggtaatgt tgtaatttct
     2761 aacaaagctt catactgatc ttcagcatct ctaaatgcgg ttaaatgcgc atcgaaagta
     2821 agcgctttca aatcttcgta tgttaaaggt ccttcaataa caaattgctt gtcatgaatg
     2881 taataatctt cggattgata cgtctttaaa tgattcatat tttcaactcc tcaatcgacg
     2941 tcgtgattgt attaaattca ttatatagaa aatttacaat aattaatact agaaaaagga
     3001 taaaagtaaa aattttgaat aattagaaat gttatgtata atattgagaa agaaagcgtt
     3061 ttcacataac aaagggggag tttcaaatga aagtcgaagt ttataaagga gcgcaaggca
     3121 aacataacct taaagattat gaagaaacat ataatacttt taattggaaa gacgtagaac
     3181 aagcattttc ttggagtgaa actggaaaaa tgaacatggc atatgaatgt atagatcgcc
     3241 atgtagatca aggaataggg gataaaatag cattaaatta caaagatgag cacagaaaag
     3301 aatcgtatac ttataaggat atgcaacggt tatctaataa agcagcgaat gttttgtctg
     3361 aacatgcaga agttgacaaa ggtgacagag tatttatatt tatgtcgcgt acacctgaac
     3421 tatattttgc gttgttaggt gttttaaaaa ttggtgcaat tgttggtccg ttatttgaag
     3481 catttatgga aaaggcagtt gtggatagat tagagaacag tgaagctaaa gtgttaatta
     3541 ctaataaggc attgttacct cgagtacctg tagataaatt accgaacttg aaaaaaattg
     3601 ttgtcgtaga tgaggatgta gaagacaatt acatagactt cattagtttg atggaaactg
     3661 ctagcgatga atttgacatt gaatggttaa agtcggatga tggtttgatt ttacattata
     3721 catcaggttc tactgggcaa cctaaaggtg tattgcatgt tcaacaagcg atgttagtgc
     3781 actatatttc tggaaaatat gtattagatt tacaagaaga tgatgtttat tggtgtacag
     3841 cagatccagg ttgggttaca ggaacatctt atggtatttt tgcaccatgg ttaaatggcg
     3901 ctacaaattg tatagctggt ggtcgctttt caccagaaca gtggtatagt atgattgaag
     3961 attttaaagt gacgatttgg tatacggcac caacagcttt aagaatgtta atgagtgctg
     4021 gtgacgatat tgttgagaaa tatgacttgt catcgttacg ttcgattctg tcagtaggtg
     4081 agcctttaaa tcctgaagtt ataaaatggg cgaaaaaagt atacggttta acggtgttag
     4141 atacttggtg gatgacagaa acaggtggac atatgattgt taactatcca acgatggacg
     4201 ttaagcttgg ctcaatgggc aaaccattac ctggtattca agctgcaatt atcgatgatg
     4261 caggtaatga attaccacca aatcgaatgg gcaatcttgc tataaaaaaa ggctggccat
     4321 caatgatgta tcgtatctgg aagaatccag aaaaatataa gtcgtatttt attggagact
     4381 ggtatgtatc tggtgactcg gcatataaag atgaagatgg ttatttctgg ttccaaggac
     4441 gtgttgatga tgtaattatg acagctggcg aacgagttgg accatttgag gttgagtcta
     4501 aattggttga acacgaagca gttgccgaag caggaattat tggtaaacct gatccggttc
     4561 gcggtgaaat aattaaggcg tttgttgcac tgaggaaagg atatgaacca acagacgaat
     4621 taaaagaaga aattcgttta tttgttaaag aaggtttgtc ggcgcatgca gcaccacgtg
     4681 aaatcgaatt taaagataaa ttacctaaaa cacgttcagg taaaattatg agacgtgtat
     4741 taaaagcttg ggaattaaat ttagatgcag gggatttaag tacaatggaa taatgacatg
     4801 aatgttatag aagatttctt tctaagaata aagggtgaca acatatttca tgtcaatgtt
     4861 taaatattag tttactttat gataagcaat ataaagagct attaacttgt gtcatatcat
     4921 ttcgtagaat gcatttgaaa atgatgacat aacaataatg gcatatcttt atattgcttc
     4981 ttatttttaa tatgatcttt ggaagatgac tattttaaat aatagaaaaa tatagttatc
     5041 aatagtatca agcgctaaaa gttgtataat acaaaacttt aataagtgaa tttattgcaa
     5101 aaatgaaagc gctaacccga tttagtcgac aagtttttaa cagttcgtta ttatatgaat
     5161 gtaagtaaaa atttcttagc tacaacttac atattataaa tgcataaatt aaacaaaaag
     5221 gggcgaaaaa agttgactca tttatcagat ttagatattg cgaatcaatc aacactacaa
     5281 ccaattaagg atattgctgc atcagtaggt atttcagagg atgcattaga accttatggt
     5341 cattacaaag ctaaaatcga cattaataaa attacgccaa gagaaaacaa agggagagtt
     5401 gttttagtaa ctgcgatgag cccaacacca gctggtgaag gtaaatcaac ggttacagtt
     5461 ggtttagctg atgcattcca tgagttaaat aaaaacgtta tggttgcatt aagagagcct
     5521 gctttaggac caacatttgg tatcaaaggt ggtgcgactg gtggtggtta tgcgcaagtc
     5581 ttacctatgg aagatatcaa cttacatttc aacggagatt tccatgcgat tacaactgca
     5641 aataatgcat tgtctgcgtt tatcgataat catattcacc aaggtaatga attaggaatc
     5701 gatcaaagac gtattgaatg gaaacgtgta ttagatatga atgatcgtgc acttagacat
     5761 gtaaacgttg ggttaggtgg acctacaaat ggtgtaccac gtgaagatgg ctttaatatt
     5821 acagtagcgt ctgaaattat ggcgatttta tgtttaagta gaagtattaa agacttaaaa
     5881 gataaaatta gtcgtattac tattggttac actagaaatc gcaagccagt tacagttgca
     5941 gatttaaaag tgcaaggtgc acttgcaatg attttaaaag atgcaattaa accaaactta
     6001 gtacaatcaa ttgaaaggac accagcatta gttcatggtg gaccatttgc gaatatcgca
     6061 cacggttgta actcaatttt agcaactgaa acagcacgtg atttagctga tatcgttgta
     6121 acggaagctg gatttggttc agacttaggc gctgaaaaat tcatggatat taaagcgcgt
     6181 gaagcaggat ttgatccggc agctgtcgtt gttgttgcga caattcgtgc attaaaaatg
     6241 catggtggtg tagcgaaaga taatttaaaa gaagaaaatg tagaagcagt aaaagcagga
     6301 attgttaatt tagagcgtca tgttaataat attaaaaaat tcggtgtaga accggttgtt
     6361 gcaattaatg catttataca tgataccgat gcagaagtag aatatgtaaa atcttgggct
     6421 aaagaaaata acgtacgaat tgccttaact gaagtttggg aaaaaggtgg taaaggtggc
     6481 gttgacttag caaatgaagt attagaagtc attgatcaac ctaattcatt taaaccttta
     6541 tatgaattag aattaccatt agagcaaaag attgaaaaga ttgtgactga aatctatggc
     6601 ggttcaaaag taacgtttag cagtaaagcg cataaacaat taaaacaatt taaagaaaat
     6661 ggttgggata attacccagt atgtatggcg aaaacacaat attcattctc agatgatcaa
     6721 acgttgttag gtgcaccatc aggatttgaa attacaattc gtgaattaga agcgaaaaca
     6781 ggtgcaggat ttatcgtagc gttgacaggt gcaatcatga ctatgcctgg tttacctaaa
     6841 aaaccagcag cattaaacat ggatgttact gatgatggtc atgcaattgg gttattctaa
     6901 taaatcatgt caattgttta ataaagataa gtaaatagtt taatagaccg gactgttgga
     6961 gatgcattat ttcagcagtt cggttttttg ctgtgctaaa aatagattcc atttggcgaa
     7021 tctaacgaca atgtttgaag gtggttaatt aatgtatatg aagataaaaa gtgggcttga
     7081 agaataggaa agcgatgcaa tgaatattca tattaaaaaa ttttaataaa ataggttgca
     7141 atatttaatt gggatgcgct acaattaaca ctaataattg atattgataa ttattatcaa
     7201 ttaaatataa tcttatagga gttgttaaca acatgaacaa acatcaccca aaattaaggt
     7261 ctttctattc tattagaaaa tcaactctag gcgttgcatc ggtcattgtc agtacactat
     7321 ttttaattac ttctcaacat caagcgcaag cagcagaaaa tacaaatact tcagataaaa
     7381 tctcggaaaa tcaaaataat aatgcaacta caactcagcc accaaaggat acaaatcaaa
     7441 cacaacctgc tacgcaacca gcaaacactg cgaaaaacta tcctgcagcg gatgaatcac
     7501 ttaaagatgc aattaaagat cctgcattag aaaataaaga acatgatata ggtccaagag
     7561 aacaagtcaa tttccagtta ttagataaaa acaatgaaac gcagtactat cactttttca
     7621 gcatcaaaga tccagcagat gtgtattaca ctaaaaagaa agcagaagtt gaattagaca
     7681 tcaatactgc ttcaacatgg aaaaagtttg aagtctatga aaacaatcaa aaattgccag
     7741 tgagacttgt atcatatagt cctgtaccag aagaccatgc ctatattcga ttcccagttt
     7801 cagatggcac acaagaattg aaaattgttt cttcgactca aattgatgat ggagaagaaa
     7861 caaattatga ttatactaaa ttagtatttg ctaaacctat ttataacgat ccttcacttg
     7921 taaaatcaga taaaaatgat gcagtagtaa cgaatgatca atcaagttca gacgcaagta
     7981 atcaaacaaa cacgaataca tctaatcaaa atacatcaac gacgaacaat actagtgatc
     8041 aaccgtacgc aacgaccaat atgagtcaac ctgcacaacc agtatcgtca gccaatgcag
     8101 atcaagcatc aagtcaacca gctcatgaaa caaattctaa tggtaatact aacgataaaa
     8161 cgaatgagtc aagtaatcag tcggatgtta atcaacagta tccaccagca gatgaatcac
     8221 tacaagatgc aattaaaaac ccggctatca tcgataaaga acatacagct gataattggc
     8281 gaccaattga ttttcaaatg aaaaatgata aaggtgaaag acagttctat cattatgcta
     8341 gtactgttga accagcaact gtcattttta caaaaacagg accaataatt gaattaggtt
     8401 taaagacagc ttcaacatgg aagaaatttg aagtttatga aggtgacaaa aagttaccag
     8461 tcgaattagt atcatatgat tctgataaag attatgcata tattcgtttc ccagtatcta
     8521 atggtacgag agaagttaaa attgtgtcat ctattgaata tggtgagaac atccatgaag
     8581 actatgatta tacgctaatg gtctttgcac agcctattac taataaccca gacgactatg
     8641 tggatgagga aacatacaat ttacaaaaat tattagctcc gtatcacaaa gctaaaacgt
     8701 tagaaagaca agtttatgaa ttagaaaaat tacaagagaa attgccggaa aaatataagg
     8761 cggaatataa aaagaaatta gatcaaacta gagtagagtt agctgatcag gttaaatcag
     8821 cagtgacgga atttgaaaat gttacaccta caaatgatca attaacagat ttacaagaag
     8881 cgcattttgt tgtttttgaa agtgaagaaa atagtgagtc agttatggac ggctttgttg
     8941 aacatccatt ctatacagca actttaaatg gtcaaaaata tgtagtgatg aaaacaaagg
     9001 atgacagtta ctggaaagat ttaattgtag aaggtaaacg tgtcactact gtttctaaag
     9061 atcctaaaaa taattctaga acgctgattt tcccatatat acctgacaaa gcagtttaca
     9121 atgcgattgt taaagtcgtt gtggcaaaca ttggttatga aggtcaatat catgtcagaa
     9181 ttataaatca ggatatcaag acaaaagatg atgctacatc acaaaataac acgagtgaac
     9241 cgctaaatgt acaaacagga caagaaggta aggttgctga tacagatgta gctgaaaata
     9301 gcagcactgc aacaaatcct aaagatgcgt ctgataaagc agatgtgata gaaccagagt
     9361 ctgacgtggt taaagatgct gataataata ttgataaaga tgtgcaacat gatgttgatc
     9421 atttatccga tatgtcggat aataatcact tcgataagta tgatttaaaa gaaatggata
     9481 ctcaaattgc caaagatact gatagaaatg tggataaaga tgccgataat agcgttggta
     9541 tgtcatcgaa tgtcgatact gataaagact ctaataaaaa taaagacaaa gtcatacagc
     9601 tgaatcatat tgccgataaa aataatcata ctggaaaagc agcaaagctt gacgtagtga
     9661 aacaaaatta taataataca gacaaagtta ctgacaaaaa aacaactgaa catctgccga
     9721 atgatattca taaaactgta gataaaacag tgaaaacaaa agaaaaggcc ggcacaccat
     9781 cgaaagaaaa caaacttagt caatctaaaa tgctaccaaa aactggagaa acaacttcaa
     9841 gccaatcatg gtggggctta tatgcgttat taggtatgtt agctttattc attcctaaat
     9901 tcagaaaaga atctaaataa ttaactggat atagcatatg tatgattaac tttgtagaca
     9961 atgtgaaagc aattaattta taaactattg attggtttaa tggctttcct ttagagtaaa
    10021 taaaaagaac agcagtgaga aattttctaa ttgaaaataa tcttactgct gtttttaata
    10081 tttggattca ttgttgtggt tactttaaaa agtgagcatc aattaacgct tttttcgatt
    10141 taacaaatgt gatttaatat catattttaa tgcgtcgttg tattcttttt cagtgatttg
    10201 atcttcgatt aacatacgct ttaatacata atgttgtctt tgaatactat atttcaaatc
    10261 tttatccgat tttaacgttc catctttttc gtagggtgta tagccataag ggctttgcaa
    10321 caaaccgata aggtatgcag attgtgcaat tgataaatct tttggtggaa taccaaacaa
    10381 actatatgaa gcggatgcaa ttccggaaat attagcgcca ttataatctc taccgaaggg
    10441 aactatattt aaatatgtat atataatttc atcttttgag agtaggtgtt ctaatctaat
    10501 tgctaggcga agttcatttg cttttctact atatgttttt tcgttggtaa gaacttgatt
    10561 tttaacaagt tgttgtgtaa ttgtgctacc acctgaactt tgatcagtat taaaaatatc
    10621 ttgtatcatt gctcttaaaa tcgcctttgg taagatgcca tcatgtttat aaaataaagt
    10681 gtcttcagat gacgttaatg ctttaatgac atttggactt gatgttttag ggcctataat
    10741 gagtgagttt tgagaatggt tatactcata taataaattt ttgttattat gatctaataa
    10801 ttcatcgcca ggtatttgtc gaactttttt tattaaagca tcatctgata atgagtcgga
    10861 cgttttagtt aaatgatgaa aatataaaga catcgcaatc acagcgatag caacgatggc
    10921 aatgaaaatc ataaatataa aaacaatgac atgtttgata gctttatata tcttttcaaa
    10981 atgatatata cgatgattca attgatgatt gttgtcttga ttcgtcatct ttaacctcct
    11041 aaattacgta tagtatacca tatttaagca atttgacttt tattttaacg ttaattataa
    11101 ttagggaaaa tgcataaaga ataggataaa aggacaagta atattatttg aaatcatcag
    11161 agagctagtg gtcgctgtga actagtgttt ttaataatat gaatacacct ttataactaa
    11221 catgtcctac gtttattaat gaacgtatca ttaatagagt gaacattatc ttatgattat
    11281 gtttaagttt ggtggtaacg tgcaatcgcg cccttacata tttgttgtaa gggttttttt
    11341 acgttcaaaa agctttaaag tattttaaca agtattcaat aaataattat aaataggagg
    11401 aaataataat gacgaatgta ttaattgaag atttaaaatg gagaggtctt atttatcaac
    11461 aaactgatga acaaggtatt gaagatttat taaataaaga acaagtgacg ttatactgtg
    11521 gtgccgatcc aacagcagat agcttacaca ttggtcactt attaccattt ttaacattaa
    11581 gaagatttca agaacatgga catcgtccta tcgttttaat tggcggtggt acaggtatga
    11641 ttggtgatcc atcaggtaaa tcagaagaac gtgtgctaca aacagaagaa caagtagata
    11701 aaaatatcga aggtattagt aagcaaatgc acaatatttt tgaatttgga acagaccatg
    11761 gtgcagtgct tgttaataat agagactggt taggacaaat ctcattaatt agctttttac
    11821 gtgactatgg taaacacgtc ggcgttaatt acatgttagg taaagattca atccaaagtc
    11881 gtttagaaca tggtatttca tatacagaat tcacatacac gattttacaa gctattgatt
    11941 tcggtcattt gaatagagaa ttgaattgta agattcaagt aggtggatca gatcaatggg
    12001 gtaatatcac aagtggtatt gaattaatgc gtcgtatgta tggtcaaaca gacgcatacg
    12061 gtttaactat tccgcttgta actaaatcag atggtaagaa atttggtaag tctgagtcag
    12121 gtgctgtttg gttagatgct gaaaaaataa gtccttatga attttatcaa ttctggatta
    12181 atcaatcaga cgaagatgta attaaattct taaaatactt tactttctta ggaaaagaag
    12241 aagttgatcg cttagaacaa tctaaaaatg aagcaccgca tttacgtgaa gctcaaaaaa
    12301 cattagctga agaagtaact aaatttattc atggtgaaga tgcattaaat gatgcaatcc
    12361 gtatttcaca agcattattt agtggtgatt taaaatcatt atcagcgaaa gaattaaaag
    12421 atggatttaa agatgtgcct caagtgacat tatcaaatga cacaacaaat atcgttgaag
    12481 tccttattga aacaggcatt tctccttcta aacgacaagc acgtgaagat gttaacaatg
    12541 gtgcgattta tattaatggt gagagacaac aagatgttaa ttatgcttta gcaccagaag
    12601 ataaaattga tggcgaattt acgattattc gtcgcggtaa gaaaaaatac ttcatggtta
    12661 actatcaata aatataattg catagctaaa taaattagag cctactcatt acattcttag
    12721 gaatgaatat gagtaggctc ttaatgtact ttactgtctg taaattatct aaagaaatct
    12781 ctatcgcctt ggccaggtga ttgacgttct gatcggcttt gacgttttgg ttgttctttt
    12841 tgttgtttta atttcacttt aacttctttt gttttaccat cacggataac ggtaacagtg
    12901 actgattcac caggtttttt attttcatat aaatagcttc ttaaatcaac atcatcttta
    12961 attttcttgc catcaatttc tgtaataata tcaccttttt taagatcaat atcactatca
    13021 gctttggcga cataaatacc gtcttctcta tcagtatgaa gttgctcgcg ctcttcttca
    13081 ggaatatctt tcaaattaat taaaccaata ccaatcgaag ggcggtcaat tttaccatgt
    13141 tttacaagtt gttcaattgt tactttaact tcattacttg gaatagcaaa cccgatacct
    13201 tcaacttgtg tcgcagcaat tttcattgag ttaataccaa ctaaattacc attaatatct
    13261 actaatgcgc cacctgagtt acctgggtta atagcagcat ctgtttgaag aacgctgact
    13321 tttgtattgc caccagttgt ctcagcgtca atcgtacgtt cgcttgctga aatgatacca
    13381 gatgttacag agttagcaaa ttgtaatcct aatgggttac ccattgcgaa tacgctatcg
    13441 ccagtttgta cttttgaaga gttggcaaat tgaatcgctt taataccttt tgtattttca
    13501 attttaagta cagcaatatc agttactgca tctttaccaa ctaatttcgc tttaacttgt
    13561 tttttattat gtaattggac tctaatttca tttgcgccat caataacatg attgtttgta
    13621 acgatataag ctgaattgtt gtttatttga tagataacac ctgaacctac tccagcttca
    13681 gatggtttag atgatttgcc ttttaataag tcgtctacac ttgatgcttt ttgcatgtta
    13741 ataactccaa caattgtagg ggagacagat tttatcattt catgaacggt accgaatttc
    13801 ttgctttgac cgtctaattg attgccacct ttattatttg ttgtctggac agttgaacca
    13861 tctttattta aaattgtact atttaatact ttgcctatac caagtactag aagtgcacca
    13921 ataattccag caatcaatgc aacgatgact gttttaaacc atggaaattt aggtcttctg
    13981 tatctaggtg tttggctatg gtttgttgta gaatgatctg tatgattaaa atctgacata
    14041 cttaacctcc attatatgat ttatatatgc tttaattatg tctttttttt ataattattg
    14101 ctagtaatac actatacaac tttagatgta ttttcagact atcttgttct agtaaaaata
    14161 tagtgataaa atctagttgt tataaacaaa taagttaagt aggtggcaca atgtattcag
    14221 tgattagtaa gattttgaat ttcattttag ttaaaatgtc aaaatcatta tacgtaatcg
    14281 gtaaagataa tattcctaag gatagtaaat atgtcgtaac ttgtacgcat gaaagttata
    14341 acgaagtcat tatgctaggt atggcattat atcctaatca aattcattat atggctaaaa
    14401 aagaattatt caaaaataaa tggattggta aatttttaac gtctttaaat gcatttcctg
    14461 tagatcgtga aaatccagga cctagtactt taaaacgccc aatcaatttg ttgaaagata
    14521 ataagacagt tggtatcttc ccaacaggtt ctcgcacatc gcaagaaggt gcacctttga
    14581 aacgtggtgc ttcaacaatt gcaatgttaa gtaagtcacc aatattacct gttgcttatg
    14641 ttggtcctac taagattcac ggtcttttaa caggacaagc atacataaat attggtaaac
    14701 caatcgatat taacgattta cctaaagatt taaaacgaaa cgagcgtatc gattatatta
    14761 caaaagagat tgaaacacga acagcaaagt tacaacaaga attgcatgaa attgtaaaaa
    14821 gtttataaaa taacttgagg tagaaatata gctggttagt aagcctaggt gactataacg
    14881 gagtatcgaa gtagttattc tagttacatt agtaatcttt atatttctac cttattttaa
    14941 gaaggatgac attcaatgta taaatttttc caaaatttag ggcgttcgtt aatgttacca
    15001 gttgccattt taccggctgc agcaattatt gccggaattg gtaatacgtt aaatgcactt
    15061 catgcgacgc cgaaaatcgc aatgttcttt actacggtag gtactacgat tttagagcaa
    15121 ttaggtattt tatttgcaat tggtgtagct ataggaatgg caaagaaaaa tgatggtgca
    15181 gtcgcgcttg cagctacgtt aggatatttt ttagttacag ttgtattatc accaatgaaa
    15241 ttagcgcctt tattaggaat gaaagcttcg gaaataaatt cagcttttga aaagatgaat
    15301 aatggcaatg tctttgttgg tattgtaata ggtttaatag cagcttatgc atacaataag
    15361 tttagtgaaa cagaattacc attagcatta tcatttttta gtggtaaacg tctagttcca
    15421 attatgactg cattttactg tacattttta gttgtcatat tgttattctt atggccacta
    15481 ctttattcat ggattgtaaa atttggtgaa tctatagtcg gtttaggatc gtttggagct
    15541 ttcatatatg gtgttgccaa tagattatta attcctacag gattacatca tgcactgaat
    15601 agtgtgttct ggtttgatac gattggtatt aatgatattg gtaaattcca aagtggcaaa
    15661 gatgctataa aaggtattac aggacgctat caagcgggat tcttcccaat catgatgttc
    15721 ggtattccag cggctgcgtt agcaatgtat catacagcta aaacgactca gaaaaaacaa
    15781 gtttacggtt ggttcctagc gagttcagtt gcagcatttt tcgttggtgt tacagagccg
    15841 attgagtttg catttatgtt tgttgcgcca atcttatatg ttgttcatgc gttattaaca
    15901 ggattatctt tatttatcgc agctacattc cattggacag ctggattttc atttagtgca
    15961 ggtttgatag attatgtgtt atcactaatt aatccagtat caaatcatcc attgatgttg
    16021 cttgttcaag gtgttgtatt tttcatctta tactatgtga ttttccgtgt agtaatccaa
    16081 gtatttaact tgaatacgat tggtagaggt gaaaatgaat tagttgatcc aacagttgta
    16141 aaagataata ttgctcctgg tgaaaatgat attaaacaaa gtaaatatca tcaacatgct
    16201 atacaaatat tagaaggttt aggtggtcaa gagaatattg ttaatttaac taattgtgca
    16261 acaaggttgc gtctagagtt aaaagacaca tctattattg atcaacagaa gattaaaaac
    16321 gccggtgcag ttggtgttac tgttaatggt aaacattcaa ctcaagttat tgtcggtaca
    16381 cacgtacagc aggttgctga tgaaattgaa aaacatttat aaaatttaaa cagctaaagc
    16441 gcaaatccaa cttcaatagg gtttgcgctt tttttagtca aatagtagaa tgatttatat
    16501 ctgaattttc agaaatggag tggggattgt gaagaaaatt ttatttgatg ttgatggcgt
    16561 ttttttaagt gaagaacgtt gtttcgatgt ctctgcatta acggtatatg aattattaat
    16621 ggataagtgt tatttaggtc ttcattcaca tatagattgg gaaactttga ctgataacga
    16681 tatacaagac attaggaatc gaatttttca aaaagataag attttaaaca aattaaaatc
    16741 gctagggcta aattcaaatt gggatatgtt atttatcgtt tttagtattc atttaattga
    16801 tattttgaaa aagttatcac atgatgaaat tgaggcattc atgtatcaag atgagcctgt
    16861 cgaattgaag ttgcaaaata taagcacaaa cttagcagac tgttttaatt taaatgaaca
    16921 actaccttta caatttttgg ataatgtaaa agttggtaaa aataatattt atgctgcttt
    16981 ggaagagttt gcaacaacag agttacatgt ttcggatgct actttattta gtttgaaggg
    17041 tgcattatgg acgttagcgc aagaagttta tcaagaatgg tatttaggat cgaagttgta
    17101 tgaagatgtt gaaaagaaaa tagcacgaac tacttttaag acaggttata tttatcaaga
    17161 aattattttg agaccagtag atgaagttaa ggtgcttctg aatgatttaa aaggtgctgg
    17221 tttcgaatta ggtattgcaa caggtcgtcc ttatactgag actgttgtgc catttgaaaa
    17281 tttaggattg ttaccatatt ttgaagctga ttttattgca actgcaagtg atgttttaga
    17341 agcagagaat atgtatccgc aagcacgacc attaggaaag ccgaatcctt ttagttatat
    17401 cgcagcttta tatggtaata atcgcgataa atatgaatct tatatcaata agcaagataa
    17461 cattgtaaat aaagatgacg tatttatagt aggcgattcg ttagctgact tattaagtgc
    17521 tcaaaaaata ggtgcaacgt ttattggaac attaacaggt ttaaaaggta aggatgctgc
    17581 aggtgagtta gaagcgcatc atgccgacta tgttattaat catttaggtg aacttagagg
    17641 tgtactagat aatttgtaat ttgattgttg tttgacagca caacttgaag tgaatgattg
    17701 aaccaaaggt ttcatattga gttacaatga aattaataat gaaaaaatgc caagaagtaa
    17761 tggaagtaat ccaatgtctt cttggcattt tgaatttaca taaattgttt atgactgtac
    17821 cgtcaattca gttgtgaaaa tttgattgta ttcaccaact tgtttaagtt catcaattat
    17881 attgtttgaa acaggttgat caacggataa aatcattagc gcatctccgc ccgcttcagt
    17941 tctacctaaa gtcatagatg caatgttgat attgtattta cctaacaatg cgccagtttt
    18001 tcctaccata cctggagtat cattatgata tgacacaatt tgatattgat ttggctttaa
    18061 gtctacagaa aaattattaa ttctaacaat tctttgaccg aaacctgtaa agacagaagc
    18121 gccaacttta acggaatcgc tatcgtttga tagttctacc tctaagtagt tactaaaacc
    18181 tgtctctgct ttattatttt caatatttaa tgtcacttgt tgttggttta acaacattag
    18241 agcattgata atattgactt caggaccaag atcatctttt aaaatatgag taataattgt
    18301 acgtgttaat aaactactat caatagaggc taagtcgcca ccgtacgtaa ttttaataga
    18361 gcttggtgca ttgtacatta attgaatagc taattcacca actgtttggc ttaaattgat
    18421 gaatgatttt acagtatcat ctatattgct taagtccatt ttaggtgcat tcactgcatg
    18481 cgttacagta ccatcaatta aaatttcgat gatttcattt gaaacagaaa ttgccacttt
    18541 ttcttgagct tcgactgttg aagcacccaa atgaggtgta acaataattt tatcatgtgc
    18601 aacaagaggc gaatcagttg caggttcatg ttcaaacaca tcgatagctg cccgactaat
    18661 ttgtccttcg tctaatgctt ttattagcgc cttttcatca ataataccac cacgtgccac
    18721 attgattatt tgcaaactag gttttgcttt ggcaaaaaag tcagcattaa ttaagccttt
    18781 tgttttaggt gttagtggtg tatgtaatgt aacgaaatca gaatgttggg caatctcatc
    18841 aactgttgcc ttcgtaatgc ttaaagattt tgctttttca tccgttaagt aagggtcaaa
    18901 agctagtatt ttcattccga aactttgcgc acgtttagca acacctaaac caattctacc
    18961 agcaccaatg acacctaatg ttttatgata aagctcagta cctttaaatg catttcgatt
    19021 ccattcttta tttgtaagtg attggtgtgc ttgcggaata tttcgagcca ttgataataa
    19081 cattgccagt gaatgttcag tagctgaaat cgtattacca tctggggcat taataactaa
    19141 aatacctttt aatgttgcag catcaatatt aatattatct acaccaacac cggcgcgtgc
    19201 gattactttt aaagaatcag cagcatttat gatattttca gtgaccgtag tttgactacg
    19261 aacgattaaa gcatggtatg aaggtataat tttgattaat gcttcttcgg acaagccagt
    19321 ttgaatatct acattaaatt tttcgtgatc taataatgct ttgataccat cttttgatat
    19381 gggatctgca acgagtacat taaattgctt catgaataac ctccatatat tttgatatac
    19441 ctttaccgat atagttaact ttacggtgtt cagttaaaat aatttctaaa gcagatacta
    19501 ccgataaaat atcgaaagga ctaattttcc ccatatgacc aattcttaaa atttgacctt
    19561 taagatggcc ttgaccacca gcaattgtta ttttaaagcg atttttaagt tcatctttga
    19621 ttattttcac ttcatcattt gtattaggtt tgaatgctgt aaccgttgga gatgcatctt
    19681 tatcattgac taataaagtt aaatctaatg cttttaaggc gcttcttaat gcatttctaa
    19741 ttgcatagtg tcgtgctatt acgtgattga aaccttctgc ttttacggtt tcaacgtatg
    19801 catttacacc tctaaataaa gacacatttg gtgtgaacgg tgtagaattg tcagcttgtg
    19861 acgaaatgta tttatttaag tctagataaa attttggtgt agttacttct ttgaaacgtt
    19921 cttttgcgcg gtggctataa gctacaaaag ctaatcctgg aggtaacata attgcttttt
    19981 gactaccaga aacaaggaca tcaattttat ctttgttaat gtcaacatca acagccccaa
    20041 tgcaacttac gccgtcaact acaaaataaa tattactatt aaattgattg atggcatttc
    20101 ctaactcgtg aatagggtgt agcactgtcg tagatgtttc gcaatattga ctaaatactg
    20161 ctttaacttc aacatctaaa gttgaaaggt aattgatgaa atctttaaca tctacagctt
    20221 ctccccatgt tacgtcataa atgtgcacat ttttgtaata agtttggcaa tttgtttaaa
    20281 tcggttacca aaggcacctg aaacaatgac aacgaagtga tcttcagggt ttacaatgtt
    20341 caacatacta gcttctaaga cgcttgtacc gctagatgtt aaaataagta catcattttg
    20401 actcccaaat attggcttta gaccttgaaa tgcttgttgt gcgatgtctt caaaatcttt
    20461 agaacgatga ccaaccatag gtgcttgaat ttctctcata atggcatcag gtacaggggt
    20521 tgggccaggt gttaataaca acggttgatg ataatacatt tatatgcctc ctataaataa
    20581 gatttcacta ttttagcaaa ttttctgaaa atttaaaagc ctaaaaaaag tgataacgct
    20641 atattgtcga ataaacgtta tcacgtaacg attttatttg gcctgaatga tgggatagat
    20701 ttttatgtct acattatttc ttacagcatt tgaaatcatg caattattat ctgcaattgt
    20761 tatcaatttt ggtaatcgct tttctaattg tgctatttga tcacttggaa tttcaatgtg
    20821 aggatggtgc acaatttttg acatactgaa ttttccatta tttaaacaag ctgttccaat
    20881 cgattgttgt tcaattgaaa tatctgtgaa ctttgcacgt tcaagagtag ctgctaatga
    20941 gatgatataa catgatgaag cggctgatac taacatttca tcgggatttg ttcctatacc
    21001 aacaccacct aaagaagcag gtattgaaat attctctgaa agtatgtcgc cttgaacgtt
    21061 tccgacattg ttacgaccac cttgccaaga agtttggact ttaaagtcat gttgatgcaa
    21121 ttgctttaac ctccaatata attgtgatag tttaatttta gaatagttta tcaaagttta
    21181 acagaaaggt gacttatcaa tgactctgaa taaactgaaa gatgaattac aaattgtttc
    21241 gcaccgtgga ttaccgagtg attttcctga aaatacaatg gtcggttatc gagaggtaat
    21301 ggggctcaat gttgctatgt tagaaataga tgttcatttg accaaagacc aacattttgt
    21361 tgtgatacat gatgaaacaa ttgatagaac atcggatggt aaggggcgta ttgctgatta
    21421 cacattatcg caattaaaat catttgattt tggtagttat aaagatgttg cttttaaggg
    21481 agaacgaata cccacgttag atgaagtact ttcattatgc ttaaagtatg ataaaaagct
    21541 attgattgaa ttgaaaagtc cgaatttata tccagaaata gaatgtaaat tgctggcatt
    21601 tttggaagaa aagaaagtcg atgcgacaca agtagttata caatcctttg atatcgaatg
    21661 catcgaaaag ttaaacacat tgggcagtat atatgaatta ggtgtgcttt gtagtaaacg
    21721 taagtattgg tataaaaagc caaacttttc aagaatttct caaattgcta gttatgttaa
    21781 tcctaattat gcattagtga ccagaaaatt tgttgatgaa gcacatcatc atcaattaca
    21841 ggttatgcca tatacagtta ataaattgaa aactggagaa aaattaagac aaatgggtgt
    21901 agatggatta attacagata acccgaaatt atttattaag tgagacgatg aatggttatt
    21961 tgatagcggg atgaggattc gtatatcgca attgataatt ttaaaaacta atgaggaaat
    22021 attatagata attcaacata taagacttgt aaattctaag ttgattgtaa aatagggtag
    22081 ctcgatataa tcttgaatct atcattttta aattaataaa aaaaacaccc acaattgtgg
    22141 gtgtttgtat tgaacggtat tatcttgagt agtactcaac gattaattgt tcgttaattt
    22201 cagcaggtaa ttcgctacgt tctggtaaac gtacgaaagt accagttaag ctgtcagcat
    22261 caaagtttaa gtactcaggt acgaaattgt tgatttcaac tgattcaacg atgatgttta
    22321 atttttgaga tttttcacga actgaaattg tttgaccagg ttttacagaa taagatggaa
    22381 tatcaacacg tttaccatct actaagatat gaccgtggtt aactaattga cgtgcttgac
    22441 gacgagtacg agctaaacct aatgaataaa caacagcgtc taaacgactt gctaataaga
    22501 tcatgaagtt ttcaccgtgt acaccgaatt ttttaccagc gatgtcaaat gtgttacgga
    22561 attgtctttc agtcattcca tataagtaac gtaatttttg tttttcacgt aattgtaaac
    22621 catattctga taatttttta cgttggtttg gaccatgttg tcctggtgcg taaggacgtt
    22681 tttctaattc tttaccagta ccgcttaaag agatacctaa acgacgagat tttttccagt
    22741 ttgaacctct gaatcgagcc ataataagac tcctccttta attctttttt gttgttatga
    22801 ataaacaaaa aagagtgttg catgcttact aagatatatt gttttatgtg tcttcacctt
    22861 atagcgacag ttacgtgaca cgtccgcatt gggaacaaca tagcgctcaa taatatacaa
    22921 ctgctacttt cgttaattca cacaaagatt attgtaacat tttcctgcta actgtcaaca
    22981 ctttattgaa aatgctgatg tccttttatg cgagttgctt ttcaataatt ttaacaattg
    23041 cttcaagatg ttctttgtca ttgtcatcaa atcgatccgt tataggggca tcgatatcta
    23101 agacgccgat aattttatca tctttgaaaa ttggaacgac aatctcagac ttactattag
    23161 catcacaagc gatatgtcct tcgaattgat gaacatcagc tacaatttgt gtacgacgtt
    23221 ctgaaacggc tgtaccacat acaccttttc caattggaat gtggacacaa gcggggtgtc
    23281 cttggaaagg tccaagtata agttcatttt gttccaataa gtaaaagccg acccaattaa
    23341 tttgatccag attatcattt aataaggcag acatgttact taaaatagca atcatgtgat
    23401 gttcatcttc aataaggctt gctgcttgtt tctttaataa tgcatagttt gttgggttaa
    23461 ttgttgtcat atttaaaacc tcttattttc atagatttta taatagtata gaatttcgaa
    23521 aatattatgg caataaattc attttataat ttatccttaa gcaaaattac gttataatag
    23581 taatgataaa ttaggaggag aagcatatgg tgttatatat cattttggca ataattgtga
    23641 ttatattgat tgctgtaggt gtattattct atttacgttc aaataaacga caaattattg
    23701 aaaaagcaat cgaacgtaaa aatgaaattg agacgttacc ttttgatcaa aaccttgcac
    23761 aattatctaa gttgaattta aaaggtgaaa caaaaacgaa atacgatgca atgaaaaagg
    23821 acaacgtaga aagtacaaat aagtatctag ctcctgtgga agaaaaaatc cataatgctg
    23881 aggctttatt agataaattt agtttcaacg cagctcaaag tgaaattgat gatgcaaatg
    23941 agttgatgga tagttacgaa caaagctatc agcaacaatt agaagatgta aatgaaatta
    24001 ttgcgttata caaagataat gatgaattat atgacaaatg taaggttgat tatcgtgaaa
    24061 tgaaacgtga tgttttagca aatcgtcatc aatttggtga ggcagcaagt ctacttgaaa
    24121 ctgaaattga aaaatttgag ccaaggttag agcaatatga agtactaaaa gctgatggta
    24181 attatgtaca agcgcacaac catatagctg ccttgaatga acaaatgaaa cagctaagat
    24241 cttatatgga agaaatacca gaattaatta gagaaactca aaaagaatta cctggtcaat
    24301 tccaagattt aaaatatggt tgccgtgatc ttaaagttga agggtatgat ctggatcacg
    24361 taaaagtaga cagtacatta caaagcttaa aaacagagct tagtttcgtt gaaccattaa
    24421 ttagtcgctt agaattagaa gaagctaatg ataaactagc taatatcaat gataagttag
    24481 atgacatgta tgatttaatt gaacatgaag ttaaagctaa aaatgatgtc gaagaaacaa
    24541 aagatatcat tacggataac ttattcaaag ctaaagacat gaattataca ttgcaaacag
    24601 aaattgaata tgtacgtgaa aactactata taaatgaatc tgatgctcaa agtgttcgtc
    24661 aatttgaaaa tgaaattcaa agtttaattt ctgtatatga tgatatttta aaagaaatgt
    24721 ctaaatctgc tgttagatat agcgaggttc aggataattt acaatattta gaagatcatg
    24781 tcacagtcat taatgacaaa caagaaaagc tacaaaatca tctgattcaa ttacgtgaag
    24841 atgaagcaga agcagaagac aatctgttac gagtacaatc gaagaaagaa gaagtgtatc
    24901 gtcgattact tgcttctaac ttaacaagtg ttcctgaaag atttatcatc atgaaaaatg
    24961 aaattgatca tgaagttcgt gatgttaacg aacaatttag tgaacgtcca atacacgtta
    25021 aacagttaaa agataaagtg tctaaaattg tgattcaaat gaatacattt gaagatgaag
    25081 caaatgatgt tcttgttaat gctgtttatg cagagaaatt aattcaatat ggaaatagat
    25141 atcgtaagga ctatagaaat gttgataaga gcttaaatga agctgaacga ttatttaaaa
    25201 ataatcgcta taagcgtgcg attgaaattg cagagcaagc tcttgaaagt gttgagccag
    25261 gtgtcactaa acatattgaa gaagaagtta ttaagcaata gaaactagta tgtagttata
    25321 cttaaataat atgagctctc tgtcaaattg gactgatgag tttaataatt gaagttagcc
    25381 aactgtatgt tgtctagctt ctttttttat atggatatat gaaagggaca ataaatataa
    25441 atagcaattg tttaaagata aacgtaatca aaagtgttgt tttaattaat ataagtagtg
    25501 aaaaaagcat aatcacacag ctgtttaata tagagtgaaa tagtctaatt cttatttaat
    25561 aagtagaaat aagattattt tgcgctataa cctttatttt ttgtcggata atagtataat
    25621 gcttgagtaa aacaatttta acgattgatg attaatgaaa gagaagtgtt tattttgata
    25681 tatctagata atgcggcaac gacgaaagca tttgaagaag tgttagatac ttatttaaaa
    25741 gtaaatcaat caatgtatta taatccgaat agtccgcata aagctggttt gcaggcaaat
    25801 caattactac agcaagcaaa agcccaaatt aatgcaatga ttaattcaaa aacaaattat
    25861 aatgttgttt tcacgagtgg tgcaactgaa tccaataatc ttgctttaaa aggtattgcc
    25921 tatcgtaaat ttgatacagc taaggaaata attacatccg tgttagagca tccatccgta
    25981 ttagaggttg taagatattt ggaagcgcac gaaggattta aagttaatta tgttgatgta
    26041 aagaaagatg gcagtattaa cttagaacac ttcaaagaat taatgtcaga caaagtcggt
    26101 ttagtaacat gtatgtatgt aaataatgta acaggacaaa tacagcctat tccacaaatg
    26161 gctgaagtta taaaaaatta tcctaaggca cattttcatg tagatgcggt tcaagcattc
    26221 ggcaaaattt caatggattt caataacgta gatagtatta gtttaagtgg acacaagttt
    26281 aatggtttaa aaggccaagg cgtcttactt gtaaatcaca ttcaaaatgt tgaaccaact
    26341 gtccatggtg gtggtcaaga atatggcgtt agaagtggaa cagttaattt gccaaatgat
    26401 attgcaatgg ttaaagcgat gaagatagct aatgaaaact ttgaagcatt gaatgcattt
    26461 gttactgagt taaataatga cgtccgtcaa tttttaaata aatatcatgg agtttatatt
    26521 aactcttcaa cttcaggttc accattcgtt ttaaatatta gttttcctgg agtaaaaggt
    26581 gaagtattag ttaatgcttt ttcaaaatat gacattatga tatctacgac gagtgcttgt
    26641 tcatctaaac gtaataaatt aaatgaagta ttggctgcaa tgggattatc agacaaatct
    26701 attgaaggta gtataagatt atcatttggg gctactacaa ctaaagaaga tatagcaagg
    26761 tttaaagaaa tatttatcat catttatgag gaaattaagg agttgctaaa ataatgaagt
    26821 atgatcactt gcttgttaga tacggggagt taacattaaa gggttcaaat agaaagaaat
    26881 ttgtaaatca attaagaaat aatgtaaata agtcattaaa aggacttgat gggtttgtcg
    26941 ttaaaggcaa acgagatcgt atgtatattg aacttgaaga ccatgcagat ataaatgaaa
    27001 taacatatcg attatcaaaa attttcggta ttaaatctat tagtccagta ttaaaagtag
    27061 aaaaaacaat agaggcaatg agtgcagcgg caattaaatt tgcgcagcaa tttgaagaaa
    27121 acagcacatt taaaattgat gtgaagcgtg ccgataaaaa tttcccaatg gatacgtatg
    27181 aattacaacg tgaattgggt ggtaccgtat tgaaacaaat tgaaaatgtt tctgttaatg
    27241 tcaaacgtcc agatcatgaa attcgagtgg aagttagatt agatgcaatt tatatgtatg
    27301 aagaagttgt tccgggttca ggcggattac cagttggtac tggtggtaag acgttactaa
    27361 tgctttcagg cggtatagac tcaccagttg ctggaatgga agtgatgaga cgtggcgtaa
    27421 caattgaagc gattcatttc catagtccac catttacaag tgatcaagca aaagaaaaag
    27481 ttattgaatt gacacgtatt ttagctgaac gtgttggacc aattaaattg catattgtac
    27541 catttacaga attgcaaaaa caggtaaata aagttgtaca tccaagatat acaatgactt
    27601 caacgagacg tatgatgatg cgtgttgctg ataaattagt acatcaaata ggggctttag
    27661 ctattgtaaa tggtgaaaac ctagggcagg tagccagtca aacacttcat agcatgtatg
    27721 caattaataa tgtaacttct actcctgtat tacgtccttt attaacttac gataaagaag
    27781 aaattattat taaatcgaaa gaaattggca catttgaaac atctattcaa ccatttgaag
    27841 attgttgtac aattttcacc cctaaaaatc cagtaaccga accaaacttt gataaggtag
    27901 ttcaatatga aagcgtcttt gattttgaag agatgattaa tcgtgctgtt gaaaatattg
    27961 aaacacttga aataactagt gattataaaa ctattaaaga acagcaaaca aaccaattaa
    28021 taaacgactt tttataaata aaatcctaga gtaaatttaa acataagggg atgttaaact
    28081 atggatttga acttaacgat gattataatc ataattttat ttggttttat cgcggcgttt
    28141 atagattcgg ttgtaggggg tggcggttta atttctacgc cagcattatt agcaatcggt
    28201 ctaccaccat ctgtggcttt aggtacaaat aaattggcaa gttcatttgg ttctttaact
    28261 agtacgataa agtttataag gtccggtaaa gtggacttat ttgttgttgc caaattattt
    28321 ggttttgtat ttttggcatc tgcatgtggc gcatatattg caacgatggt tccgtcacaa
    28381 atattgaaac ctttaatcat cattgcactt tcgtcggtgt ttatattcac attacttaaa
    28441 aaagattggg gcaatacacg tacgtttact caatttacat ttaagaaagc cataatattt
    28501 gcagcacttt ttatattaat cggcttttat gatggatttg taggtggggg aacaggttca
    28561 tttatgcttt ttgtattgtt aatctttggt tttgattttt taagtgctgc aggaaatgct
    28621 aaagttttga actttgcttc taatataggt gcgcttgtat tatttatggt attaggacaa
    28681 gtagattatg taataggttt aattatggct acaagcatga ttgctgggtc atatactgga
    28741 gcacattttg ctatcaaaca aggtgttgcc tatgtaaaag tattatttat tattattact
    28801 gctattttaa ttttaaaaaa tgcttttgat tatattcaac aatttgtata aaattaaatt
    28861 tgcttttgat taaagcatga aaattgtaat caaaccataa attgtcgtat gatgtagtta
    28921 gaattttaaa atgcaggagg tcaagtatat gactgaaata acattcaaag gtggaccaat
    28981 ccacttaaaa ggtcaacaaa ttaatgaagg tgattttgca cctgatttta cagtgttaga
    29041 taatgactta aatcaagtaa cattagcaga ttatgctggt aaaaagaaat taattagtgt
    29101 ggtaccatca attgatacag gtgtttgtga tcagcagact cgcaaattca actctgaagc
    29161 ttctaaagaa gaggggattg tgcttacaat ttcagcagac ttaccattcg cacaaaaaag
    29221 atggtgcgct tcagcaggtt tagacaatgt cattacatta agtgaccacc gtgacttatc
    29281 atttggtgaa aactatggcg ttgttatgga agaacttcgc ttattagctc gtgcagtatt
    29341 tgtattagat gcagataata aagttgttta taaagaaatc gttagtgaag gtactgattt
    29401 cccagatttt gatgctgctt tagctgcatg caaaattatt taatcattaa agagataaat
    29461 cttaaaatgt atacatcgtg tccatcgttg tcaacagcat taaaatagaa ttgttttcta
    29521 tgattgctaa gacctatggg cactttttat tggagaggga cgaatatggc agaacaacaa
    29581 acaattatgg aacgcttgtt tcatacatta gatgaaaaag ctaaaacatt aaataatgaa
    29641 aatggccaaa gttttattga aaatcttggg ctagcaatgg aacaagtata taccaatgaa
    29701 agaggattgt tagaacaatc gacgttacaa gatcgacgta aagcattcca atttgcatat
    29761 ttaagtttaa tgcaggaaga aaagatacaa gcaaatcatc aaattacacc agattcaatt
    29821 ggattgatac taggattttt agttgagcgt tttatgaaca accaagaaga attacatatt
    29881 gttgatattg caagtggtgc cggtcattta agtgctactg taaaagaagt gttacctgaa
    29941 attgcggtta tgcatcattt aattgaagtt gatccagttt tatcacgtgt tagtgtacat
    30001 ttagcaaact tcttagaaat tcctttcgat gtgtatcctc aagatgccat catgccacta
    30061 ccattagaag aagcagatat cgttattggt gattttccag taggctatta tccaattgat
    30121 gaaagaagta aggagtttaa gctaggtttt gaagaaggac atagttattc acattattta
    30181 ttaatagaac aagcaataaa tgcattaaaa gatgctggat atgcctttct agtggtacca
    30241 agtaatattt ttacaggtga acatgtaaaa cagcttgaaa aatatattgc aacagagaca
    30301 gagatgcaag catttttaaa tttaccacca actttattta aaaatgaaaa agcgcgaaaa
    30361 tctatattaa ttttacaaaa gaaaaaatcg ggtgaaacaa agccagttga agtattattg
    30421 gcaaatattc ctgatttcaa aaatccttca caatttcaag gatttatgac agagttaaat
    30481 cagtggatgg acacaaatcg tcctaaaaaa taatctgtaa tagtatagtc ataaaactgt
    30541 atgaatgata aaatgagaaa tgaaatagta taaaaagcaa acgatggagg atcattactt
    30601 atgtcaaaat taatcttggc tatcaatgct ggtagttcat cattaaaatt tcaattaatt
    30661 agaatgcctg aagaggaatt agtaacaaaa ggtttaatag aaagaatcgg attgaaggat
    30721 tcaattttta caattgaagt caacggggaa aaagttaaaa cagtacaaga tatcaaggat
    30781 cacgttgagg cagttgatat catgttggat gcttttaaag cgcataatat tattaatgat
    30841 attaacgata tcgatggaac aggtcaccgt gttgtacatg gtggtgaaaa attccctgaa
    30901 tcagtagcta ttactgatga ggttgaaaag gaaattgaag aattaagcga attagcaccg
    30961 cttcacaacc cagctaactt gatgggtatt cgtgctttcc gtaaattatt accaaatatc
    31021 cctcatgtgg caatttttga tacagcattc catcaaacaa tgcctgaaaa agcatatcta
    31081 tatagcttgc catatcatta ttataaagat tatggcattc gtaagtatgg tttccatggt
    31141 acaagccata aatttgtatc acaaagagcg gcagaaatgt tagataagcc aattgaagat
    31201 ttacgtatta tttcatgtca cattggtaat ggagcatcaa ttgcagctat cgatggcggt
    31261 aaatctattg atacatcaat gggcttcaca ccacttgctg gtgtaacaat gggtactcgt
    31321 tctggtaata ttgaccctgc tttaattcca tttattatgg aaaaaacagg taaaactgct
    31381 gaacaagtat tggaaatctt aaacaaagaa tcaggtttat taggattatc aggtacatct
    31441 agtgatttac gtgacttatc agaagaagct gaatcaggta aagcacgttc acaaatggct
    31501 ttagatgtat ttgcttctaa aattcacaaa tatattggat catatgctgc gagaatgcat
    31561 ggtgttgatg ttatcgtatt tacagcaggt atcggtgaaa actcagtaga aattcgtgcg
    31621 aaagttcttg aaggcttaga atttatgggt gtttactggg atcctaagaa aaatgaaaac
    31681 ttactacgtg gtaaagaagg atttattaac tatcctcatt caccagttaa agttgtcgtt
    31741 attccaactg atgaagaaag tatgattgcc cgtgatgtta tgacattcgg tggtttaaaa
    31801 taatttttaa ataaatatta agcgtctatc tccgctacaa ttatatgtag gaggtagacg
    31861 ctttttgtat tgtttgaaaa ttaactagtg taatgtctct tttcacgaat atcttaaaga
    31921 attaagtagt cgaagaagat tatgaaaaca ttattaagtg agttttattt ataaacaata
    31981 aaaaaccaag tacagaaagt tgcacttggt tcataatgat caagtagtta tctaatgatc
    32041 atctatattt aattttgata tttttcacgt aattgagttg ttgcaacttg tggttggaag
    32101 tctgctggta actcttcagt acgaacaact aacacgtcac atggcgcatg acgaacgata
    32161 gattctgata cagaaccaac aataaatctt tccacggcat ttaagcctga tgtaccactc
    32221 ataatcaagt ctgcattaat ttcatgtgca agctttttag gaatgataga tttaggagag
    32281 ccaaactcta gacgcgtttc tacatcttta acaccagcgt tagtagctac ttctttataa
    32341 ccatttaata attcttctgc aaaatgctta gatttttcag taaattgagc atcataaact
    32401 tcataagaag aatatgttct tgaatcaatt acattcacaa ttgttaactt cgcatcgtta
    32461 cgtttagcaa caccaactgc tctgttaaat gcccattccg cttcatgtga accgtcaact
    32521 gcgattaaaa tatttttgta agtaatcata gtaagtgcct ccttgttctt tcttaattat
    32581 attttaccac aattttcgga aaagtcagtg taataacctt tacaattttg tggatttttg
    32641 attgcgcttt caaaatggtc gcgttaagat ggttatggag gtggatggta tgaaaattgg
    32701 tataccaagg gagattaaaa ataatgaaaa tcgtgttggt ttatcaccaa gtggtgtgca
    32761 cgctttagta gaaagtgggc atactgtttt agtggaaaca aatgcgggtt caggatcgtt
    32821 ctttgaagat gtagattaca aagaagcagg tgctgagatt gttgctgaac aagcaaaagt
    32881 ttgggatgtg gatatggtta ttaaagttaa agaaccactt gaatctgaat atccatattt
    32941 taaagaaggg cttgtattat tcacttatct tcatttagca aatgaagaaa aattaacaca
    33001 agctttgata gatagaaaag taattagcat tgcatatgag actgtgcagt taccagaccg
    33061 atctttacca ttgttatcac caatgagtga ggtagcagga agaatgtcag ctcaagttgg
    33121 cgcagagttc ctacaaaaac ttaatggtgg tatgggaatt ctactaggtg gtgtcccagg
    33181 agtacctaag ggtaaagtaa ctattatcgg tggtggtcaa gcaggaacaa atgcagctaa
    33241 aattgcacta ggactaggtg cagatgttac gattttagat gttaatccaa agcgtttaca
    33301 acaattagat gatttattcg gtggacgtgt acatacaatt atgtcaaatc cgttgaatat
    33361 tgagttgtat gttaaacaaa gtgatttagt aataggtgca gttttaattc caggtgctaa
    33421 agcgccaaga cttgtaacag aagacatgat taaacaaatg aaaaatgggt cagttattat
    33481 tgacattgct attgatcaag gcggtatttt tgaaacaact gataaaatta cgacacatga
    33541 tgatcctaca tatattaagc atggtgtggt tcattatgca gttgcaaata tgccaggtgc
    33601 agtaccgcgt acttcgacgt tagctttaaa taatgctacg ctaccttatg cgctcatgct
    33661 agctaataaa gggtatagag aagcatttaa atcaaatcaa ccattatcat taggtttaaa
    33721 tacttacaaa ggtcacgtaa ccaataaagg cgttgcagag gcatttgaaa tggaatataa
    33781 atctgtagaa gaagcattac aattataatt tgaatttaat gaaaagggaa tggattacag
    33841 cgtactaaag aatgacgtta tcatctcctt ggttattaaa attaaataat gataaattaa
    33901 agctagaaac aatgcgaaga aatcatcgaa catgaatgat attgatttga ttcattacat
    33961 gttactgatg aacatacctg catatgtgtt tctagcttgt ttgttacata ttgcatttag
    34021 acttggacaa aaatttatgt cctaggcgct acaatgttat attggcagtg tttgactgaa
    34081 tgagaatgcg cttgtaacaa gcttttcatt tttgtctcac tccttatttt tcgtaatgtg
    34141 ttaatacttc atatccttca ttagtgacaa gtatgtcatc ttcaattctt acacctgcaa
    34201 cacctggtac ataaatacct ggttcgattg taatgaccat gccagcttct aacaaattag
    34261 aattagtact tgaaacatct tgatattcat gttcttgtaa tcctagacca tgacctaagc
    34321 gatgagggaa atattcacca taaccttttt ctgaaataat atttctagcg atatgatcga
    34381 tatcttttaa aggtattcca ggtttaattg cttggattgc agatgtttct gcttctaata
    34441 caatattata aatttcttgt gtttctttgc taggttcacc aaatttaatg gtacgtgtca
    34501 tatcgctaca ataatgctca taaattacac ctaaatcaaa tagtacatat tcattgcttt
    34561 ttaatctgcg atctcctggt gtgccatgag gtgatgcggc atgatctcca aataaaacca
    34621 tcgtatcaaa actcatttca ttgacgccgt attgtttgat tgtttgctca atatggttga
    34681 ctacttcacg ttcagtcaca ccttctttta aataagaaac acctatttcg atacacttat
    34741 ctgctaactc agcagcttta cgtattttac taatttcatc ttcggattta atatttctca
    34801 attgtttgat tgttaaatca acatctccga atgaattgac attgaaacca gagattaatt
    34861 gtttttggcg tgctactgtt aagtgctcgc tttcaattag taatttattg attgtttgag
    34921 gataaagtga aaaaggattt tcagtgtcta aatatccaac gatttcacct gtgaaaggtg
    34981 atgctttgac ttcttcgact tccatttttg gacaaaatag tacttgtttc ccatctttct
    35041 taatcaataa tgcaaataat ctttcatggg gttcgctacg gtatccagta aagtaatata
    35101 cattcaacgg tgttgtaatc catgctgcat cagcttgtcg attgttcagt tcgtctatta
    35161 tttttgatat ttttgtcatt ttataaacac tcctcaacat aatattactt ccattttatg
    35221 ccaattatta ttagatttca aaatcaagct aattcattaa ctagattttc aatttttaaa
    35281 atttgagaat ttgttataat taagaggcaa aagggtacta aatttatata gcaattgata
    35341 ggaggatgct caaatgaagt tatcatttca tggtcaatca acgatttatt tagaagggaa
    35401 caacaaaaaa gttatcgtag atccgtttat ttcaaataac cctaagtgtg atttgaatat
    35461 tgaaacagtg caggtagact atatcgtttt aacgcacggt cattttgatc actttggtga
    35521 tgttgtggaa ctagcaaaga aaacaggagc aacagtaatt ggaagtgcag aaatggctga
    35581 ctatctttct tcatatcacg gtgttgaaaa tgttcatggt atgaatatag gtggtaaagc
    35641 aaactttgat ttcggaagcg ttaaatttgt tcaagcattt catagttcaa gttttacaca
    35701 tgaaaatggt attccagttt atttaggtat gccaatgggt atcgtgtttg aagttgaagg
    35761 gaaaacaatt tatcatactg gtgatacagg tctgtttagt gacatgtcac ttattgcgaa
    35821 acgtcatcca gttgatgtat gttttgtacc aattggagat aattttacga tgggtattga
    35881 tgatgcaagt tatgctatta atgaatttat taaaccaaaa atttctgtac cgattcatta
    35941 tgatacattc ccattaatcg aacaagatcc acaacaattt aaagatgctg ttaatgtagg
    36001 ggacgtgcaa attttaaaac caggtgaatc tgttcagttt taaatagaat atagatttta
    36061 cactaaaaaa cacctcgcta atctatgtgg aagttatcgt ctgcatattt ttagtgggtg
    36121 tttttatatt ctactaattc agttacgacg tggacggggg acatcagtgg ttctttatca
    36181 tttctgacct actctcgtaa ttttagtttt atacaattag acattgatta taaatttact
    36241 acgatataaa aaatccagaa ccacagtcat aatcatttct tgtgtttact tagtcgtttg
    36301 agactgcatc atgattgaaa gattatttgt gattctggat aaaaatttta tttaacgatt
    36361 aatacaggga tagtcgcacg ttttgctact ttgtggctga cacttccaag tacaaatttc
    36421 tttttgtctt ctgctttacg gttacttaaa acaacaattt cgtatttacc gctattagca
    36481 tgttttaata gttcttcttt tgcattacca cgaacaatta tttggtcata atcaatacca
    36541 taatcttcta aagctttgcg tgttttttcc aatcgcttgc ttcgttcttc agtaagtttg
    36601 tttaaatgaa cacctgcttt aattgatgct tgagcatctt gttcgctgat tgcgtttaaa
    36661 actgttacga ctgtaccttc gccagctaat ttagacactt cttttagtgc tttttcattt
    36721 tttaactgag tgtctacacc aagtaatata tttttataca ttagtacatc cctcctcact
    36781 tacattctaa taaataataa tggatttttc catttaaaat taaagatttt gtgatctttg
    36841 tgtttgttgt atattttcaa aaaataaaat aggtgaaacg atcattattt catttcactt
    36901 caatgctttt tatccaaaat aaagttataa tgtagttaat actgttcgaa aagaagaggt
    36961 aaagaatgac aaaacatgaa caaattttag attatattga atcgttatct ataggctcta
    37021 aaatttcggt gcgtaaaatc gctaaatttt taaacgtatc tgaagggaca gcatatcgtg
    37081 caattaaaga tgctgataaa atgggcatgg tcgcaacgat agatcgtgtt ggtacggttc
    37141 gaatcgaaaa acgtaatcgt aatgaaattg aacatttaac ttttaatgaa attgtcaata
    37201 ttattgatgg ccaagtgtta ggtggcaata aaggtatcac taagatggta tctaaatttg
    37261 caattggagc aatggaactc aaagatattt taaaatatat tggtccaaag acattattga
    37321 ttgtcggaaa tcgcgaagat gtgcagattg aagctttaaa aagaggtacg gctatattaa
    37381 ttactggtgg atttaagcca tctaataaag ttattaattt tgcgaatgaa catgatttac
    37441 ctgttctatc atcaagttat gatacattcc tagttgcaaa tattatcaac aaagcacttt
    37501 ttaatcagaa aatacgaaaa gatatcttaa tagttcaaga tataatgacg ccattagatg
    37561 atttatctgt gctgtttgat acgatgaaaa tagcagatta taagcgtatg gcgaatcgaa
    37621 ctggccatac aagatttccg gtagtcaatg agtcttataa attagtaggt attgtaacaa
    37681 gtcgagagat gattaataca aaggacgacg acgaaataga taaagtgatg acgcgaaatc
    37741 ctatttatgt aaatgctatg agtacagtag caagttgtgc gcatatgatg atttgggaag
    37801 gtattgaatt gattcctgtc gtttcgagta ataaaaagac agtgggtgtg attaatagac
    37861 aagatgtttt aaagtctatg caacttttag gaagacagcc tcagatgggt gaaacaatta
    37921 acgatcaaat cgccaaatat ataacaatga atcaagatgg aattacagta gaagtttcac
    37981 cacttttaat caatcattac ggaacagtaa gtaaagcggc atttgtaagt attatagaag
    38041 aaacaataca atatgaaatg cgtaaattta aaaaaggtaa tgtcatgata gagaacttaa
    38101 atatcgtgta tattaaaaca gtacctattg aatcacatat aacagtgcgc tttggcatac
    38161 tagacgtcgg aagaaacttc gccaaaatag aagtgaacat gcatagtcaa aacgacaaag
    38221 tagcgagcgc tctcgtgata tgccaaatgt ttgacgaagt ataggaactt agcagagaaa
    38281 ataggcataa gatagatttc gcacaaacgt tggagcccaa cttgcacatt atagtaagct
    38341 gacattacgt cagcttctgt gttgtggccc atcccaactt gcattgtttg tagaatttct
    38401 tttcgaaatt ctctatgttg gggcccctga actaaatagt atgaaaatat atatctaaat
    38461 aattaaaacg ggcaaatagt ttaatatggt agtaacaatt tttataattt agatattttg
    38521 atatagacta atgcttaaat taagcaactt ttctaaaaaa gggagtatga aaatgattag
    38581 tactttgaat gaaattatga aatgtatcga agacaacgat acaattatta tacacagaca
    38641 tgttagacca gatcctgatg catatggttc acaacttggt ttaaaatact atattcagca
    38701 gaaatttccg caaaagcaag tatttgcagt gggtgaagcg gaatcatcat taagttttat
    38761 tggagagtta gataacattg atgataaaac atatcaagat gcgcttgtaa ttgtatgtga
    38821 tactgccaat gctccacgaa ttgacgatga acgttatagt acaggtcgta aacttattaa
    38881 aatagatcat catcctgcag ttgatcagta tggtgatatt aatttagtta atacgaacgc
    38941 gtcatctaca agtgaaatca tttacgattt aatctcacat tttaatgatg aagcaattgt
    39001 taataaagat atcgcgagcg ttttatatct tggtatcgtc ggtgatactg ggcgattcct
    39061 ttttaacaat acctcagaac atactatgga aattgctgga aagttaattg ggcatgatat
    39121 tgatcataat gcgcttttaa ataaaatgat ggagaaggat ccaaaaatgt tgccgtttca
    39181 aggttatgtt ttacaacatt tcgaacttat gggtgatgga ttctgccaag ttaaaataac
    39241 tgaagatgta ttggagcaat tcggtattca gccaaatgaa gcatctcagt ttgttaatac
    39301 aattgctgac atcaaaggct tgaaaatatg ggtgtttgca gttgatgagg gtagtgaaat
    39361 aagatgtcgc ttacgctcta aagggcaatt gattattaat gatattgcgc aagattttgg
    39421 tggcggtggt catccgaatg cgtcaggagt ttcagtggac agctgggatg aatttgagca
    39481 acttgctaca gctttacgca caaaacttaa ctaatagaaa ggagccattc aatcatggcg
    39541 gcatatttaa atattcatac ggcttatgat ttgttaaatt caagcttaaa aatagaagat
    39601 gccgtaagac ttgctgtgtc tgaaaatgtt gatgcacttg ccataactga caccaatgta
    39661 ttgtatggct ttcctaaatt ttatgataca tgtattgcca ataatataaa gccgattttt
    39721 ggtatgacaa tatacgtgac aaatggatta aatacagtcg aaacagttgt tctagctaaa
    39781 aataatgatg ggttaaaaga tttgtatcaa ctatcatcgg aaataaaaat gaatgcatta
    39841 gaacatgtgt cgtttgaatt attaaaacga ttttctaaca atatgattat catttttaaa
    39901 aatgttgcag acgaacatcg tgacattgtt caagtttttg attcgcatga agatacgtat
    39961 ttagatcatc gaagtgtttt agttcagggt ataaagcacg tatggattca aaatgtttgt
    40021 taccaaacac gtcaagatgc agatacaatt tctgcactcg cagcgataag agacaataca
    40081 aaattagact taattcatga tcaagaagat tttggtgcgc attttttaac tgaaaatgag
    40141 attcagcaac ttgatgtgaa tcaagaatat ttaacgcagg ttgatgttat agctcaaaag
    40201 tgtaatgcag aattaaaata tcatcaatct ctacttcctc aatatcagac acctaatgat
    40261 gaatcagcta aaaaatattt gtggcgtgtc ttagttacac aattaaaaaa attagaactt
    40321 aattatgacg tctatttaga gcgattgaaa tatgagtata aagttattac taatatgggt
    40381 tttgaagatt atttcttaat agtaagtgac ttaatccatt atgcgaagac acatgatgtg
    40441 atggtaggtc caggtcgtgg ttcttcagct ggctcactgg tcagttattt attgggaatt
    40501 acaacgattg atcctattaa attcaatcta ttatttgaac gctttttaaa cccagaacgt
    40561 gtaacaatgc ctgatattga tattgacttt gaagatacac gccgagaaag ggtcattcag
    40621 tacgtccaag aaaaatatgg cgagctacat gtatctggaa ttgtgacttt cggtcatctg
    40681 cttgcaagag cggttgctag agatgttgga cgaattatgg ggtttgatga agttacatta
    40741 aatgaaattt caagtttaat cccacataaa ttaggaatta cacttgatga agcatatcaa
    40801 attgacgatt ttaaaaagtt tgtacatcga aaccatcgac atgaacgctg gttcagtatt
    40861 tgtaaaaagt tagaaggttt accaagacat acatctactc atgcggcagg aattattatt
    40921 aatgaccacc cattatatga atatgcccct ttaacgaaag gggatacagg attattaacg
    40981 caatggacaa tgactgaagc cgaacgaatt gggttattaa aaatagattt tctagggttg
    41041 agaaacttat cgattattca tcaaatctta acacaagtca aaaaagattt aggtattaat
    41101 attgatatcg aaaatattcc gttcgatgat caaaaagtgt ttgaattgtt gtcgcaagga
    41161 gatacaactg gcatattcca attagagtct gacggtgtaa gaagtgtatt aaaaaaatta
    41221 aagccggaac actttgaaga tattgtggct gtaacttctt tgtatagacc aggtccaatg
    41281 gaagaaattc caacttacat tacaagaaga catgatccaa gcaaagttca atatttacat
    41341 ccacatttag aacctatatt aaaaaatact tacggtgtta ttatttatca agagcaaatt
    41401 atgcaaatag cgagcacatt tgcaaacttc agttatggtg aagcggatat tttaagaaga
    41461 gcaatgagta aaaaaaatag agctgttctt gaaagtgagc gtcaacattt tatagaaggt
    41521 gcaaagcaaa atggttatca cgaagacatt agtaagcaaa tatttgattt gattctgaaa
    41581 tttgctgatt atggttttcc tagagcacat gctgtcagct attctaaaat tgcatacatt
    41641 atgagctatt taaaagtccg ttatccaaat tatttttacg caaacatttt aagtaatgtt
    41701 attggaagtg agaagaaaac tgctcaaatg atagaagaag caaaaaaaca aggtatcact
    41761 atattgccac cgaacattaa cgaaagtcat tggttttata aaccttccca agaaggcatt
    41821 tatttatcaa ttggtacaat taaaggtgtt ggttatcaaa gtgtgaaagt gattgttgat
    41881 gaacgttatc agaacggcaa atttaaagat ttctttgatt ttgctagacg tataccaaag
    41941 cgagtcaaaa cgagaaagtt acttgaagca ctgattttag tgggagcgtt tgatgctttt
    42001 ggtaaaacac gttcaacgtt gttgcaagct attgatcaag tgttggatgg cgatttaaac
    42061 attgaacaag atggtttttt atttgatatt ttaacgccaa aacagatgta tgaagataaa
    42121 gaagaattgc ctgatgcact tattagtcag tacgaaaaag aatatttagg attttatgtt
    42181 tcgcaacacc cagtagataa aaagtttgtt gccaaacaat atttaacgat atttaaattg
    42241 agtaacgcac agaataataa gcctatatta gttcagtttg ataaagttaa acaaatccga
    42301 actaaaaatg gccaaaatat ggcattcgtc acattaaatg atggcatcga aactttagat
    42361 ggtgtgattt tccctaatca gtttaaaaag tacgaagagt tgttatcaca taatgacttg
    42421 tttatagtta gcgggaaatt tgaccttaga aagcaacaac gtcaattaat tataaatgag
    42481 attcagacat tagccacttt tgaagaacaa aaattagcat ttgccaaaca aattataatt
    42541 agaaataaat cacatataga tgcgtttgaa gaggcgatta aagctacgaa agagaatgct
    42601 aatgatgttg tgttatcctt ttatgatgaa acgattaaac aaatgactac tttaggctat
    42661 attaatcaaa aagatagtat gtttaataat tttatacaat cctttaaccc tagtgatatt
    42721 aggcttatat aacttttatc aactaataaa ttatgatata gtaaactgat ggttagatat
    42781 tttttaacca tcagtttgcg tttatattag ttttttatgc ttattatttt tatgagtttc
    42841 actttacatt attgattaat ccataagaat aattagcaca aaaagcagta tacataaatt
    42901 gagtaaagaa ttttgtcgat atatcgtgcg aaaaaataat aactttttga tatattggtt
    42961 tttgctatc
//
LOCUS       DAPSKH010000014        42894 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPSKH010000014 DAPSKH010000000
VERSION     DAPSKH010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 42894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42894
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.014"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            89..1435
                     /locus_tag="RPH49_000877"
     CDS             89..1435
                     /locus_tag="RPH49_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDY5124060.1"
                     /translation="MAKHPFEQFNLESSLIDAVKDLNFEKPTEIQNRIIPRILKRTNL
                     IGQSQTGTGKSHAFLLPLMQLIDSEIKEPQAIVVAPTRELAQQLYDAANHLSQFKAGV
                     SVKVFIGGTDIEKDRQRCNAQPQLIIGTPTRINDLAKTGHLHVHLASYLVIDEADLMI
                     DLGLIEDVDYIAARLEDNANIAVFSATIPQQLQPFLNKYLSHPEYVAVDSKKQNKKNI
                     EFFLIPTKGAAKVEKTLNLIDILNPYLCIIFCNSRDNANDLARSLNEAGIKVGMIHGG
                     LTPRERKQQMKRIRNLEFQYVIASDLASRGIDIEGVSHVINFDVPNDIDFFTHRVGRT
                     GRGNYKGVAITLYSPDEEHNISLIENRGFVFNTVDIKDGELKEVKAHNQRQARMRKDD
                     HLTNQVKNKVRSKIKNKVKPGYKKKFKQEVEKMKRQERKQFSKQQNRQKRKQNKKG"
     gene            1445..2335
                     /locus_tag="RPH49_000878"
     CDS             1445..2335
                     /locus_tag="RPH49_000878"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDY5124061.1"
                     /translation="MLLGSHVSMSGKKMLEGSAIEAHEYGETTFMIYTGAPQNTRRKS
                     IEDLNITKGHEVMEKYGLSNIVVHAPYIINIANTTKPETFNLGVDFLQQEIERTQAIG
                     AKDIVLHPGAHVGAGVDAGINKIIEGLNEVLTNDNNVRIALETMAGKGTEIGRSFEEL
                     ARIIDGVHNNERLSVCFDTCHTHDAGYNVKEDFDGVLNEFDKIIGVDRIKVVHVNDSK
                     NDRGAQKDRHENIGFGYIGFDALNYIVHHDSFKDIPKILETPYVGEDKKNKKPPYKLE
                     IEMLKQQQFDPELKNKVMQQ"
     gene            2461..3246
                     /locus_tag="RPH49_000879"
     CDS             2461..3246
                     /locus_tag="RPH49_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDY5124062.1"
                     /translation="MRGENTMTPVFELKNVNYYYDHKKVLENINIKINKGEFLAIVGP
                     NGAGKSTLLKLILGLLPLQSGEIFVEGIDFKNKKTSIKLSYVSQKANAFNSGFPASVK
                     EVVLSGLTKTKRLFQTFNSKDNEKVIKVLERLNISDLIHKNIAELSGGQQQRVMIARA
                     LISEPAVLVLDEPTNGIDAKHVSEFYNTLDQLKQEGITIILVTHDIGVVADTATEVAC
                     LNKHLHFHGTTDEFKSLDEVEISKIYGHPVRFVDHQHNRECCN"
     gene            3288..4151
                     /locus_tag="RPH49_000880"
     CDS             3288..4151
                     /locus_tag="RPH49_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDY5124063.1"
                     /translation="MIDALLNFDFMRYSLISGILIGFIAPLIGAFIVVRRLSLIADAL
                     SHVTLGGISFGMFLLTIMPTLVFINPMWFGILFAIVGALLIEKLRTSYTAYQEIAIPI
                     IMSAGIALSAIFISLADGFNQEIVGLLFGSISAVNISDLTTIIVIAIIVVLFITLFYK
                     ELFILSFDEEYSKVIGIPKWIQFLFIVIVAMVISASMRVVGILLVSALITLPIAISMR
                     ITKSFKQLILLSVFLGELSVILGLVLAFYMDISPGGVIVVLLVILLMITMAYQKMRMK
                     FKKGANINEYK"
     gene            4138..4548
                     /locus_tag="RPH49_000881"
     CDS             4138..4548
                     /locus_tag="RPH49_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDY5124064.1"
                     /translation="MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVM
                     DENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKV
                     IDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD"
     gene            4824..5423
                     /locus_tag="RPH49_000882"
     CDS             4824..5423
                     /locus_tag="RPH49_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDY5124065.1"
                     /translation="MAFELPKLPYAFDALEPHFDKETMEIHHDRHHNTYVTKLNAAVE
                     GTDLESKSIEEIVANLDSVPANIQTAVRNNGGGHLNHSLFWELLSPNSEEKGTVVEKI
                     KEQWGSLEEFKKEFADKAAARFGSGWAWLVVNNGQLEIVTTPNQDNPLTEGKTPILGL
                     DVWEHAYYLKYQNKRPDYIGAFWNVVNWEKVDELYNATK"
     gene            5544..7619
                     /locus_tag="RPH49_000883"
     CDS             5544..7619
                     /locus_tag="RPH49_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDY5124066.1"
                     /translation="MLKRLKEKSNDEIVQNTINKRINFIFGVIVFIFAVLVLRLGYLQ
                     IAQGSHYKQIIKNDENITVNESVPRGRILDRNGKVLVDNASKMAITYTRGRKTTQSEM
                     LDTAEKLSKLIKMDTKKITERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDK
                     QLLSKIGKSQLDELSSKDLQVLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSK
                     LPGVNTSMDWDRKYPYGDTLRGIFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYL
                     EYQYEDVLRGKKKEMKYTTDKSGKVTSSEVLNPGARGQDLKLTIDIDLQKEVEALLDK
                     QIKKLRSQGAKDMDNAMMVVQNPKNGDILALAGKQINKSGKMTDYDIGTFTSQFAVGS
                     SVKGGTLLAGYQNKAIKVGETMVDEPLHFQGGLTKRSYFNKNGHVSINDKQALMHSSN
                     VYMFKTALKLAGDPYYSGMALPSDISSPAQKLRRGLNQVGLGVKTGIDLPNETKGQIE
                     PLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTIANDGYRIQPHIGLTIHESTNKDEVGP
                     LKKKINGTVLNKVNNTENEIKQIQEGFKMAFNDKDGTGYVSFKDTVVPTAGKTGTAEV
                     FQNGEPRVNSTYIGYAPIDDPKLAFSIVYTNQPVPPPWLTGGDLGRDVINYYFKQLGK
                     DDKNKDKDK"
     gene            7732..7881
                     /gene="rpmG"
                     /locus_tag="RPH49_000884"
     CDS             7732..7881
                     /gene="rpmG"
                     /locus_tag="RPH49_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDY5124067.1"
                     /translation="MRVNVTLACTECGDRNYITTKNKRNNPERVEMKKFCSRENKQTL
                     HRETK"
     gene            8090..8629
                     /locus_tag="RPH49_000885"
     CDS             8090..8629
                     /locus_tag="RPH49_000885"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDY5124068.1"
                     /translation="MTKNEIRKYILHKMKNFNKAEKRKADTWLRNQFFATEEYKEANA
                     IALVLSFNHEVDTFSIIEQALMDHKRIFVPKMDYLNHQMTFKEIFNLKDIDVDNKGVY
                     YPTSKGETTNNLDLIVVPGVGFQDDGYRIGYGGGYYDRFLANYQTKTISLLYDFQITS
                     FEPESFDQPVDKLIIYQSA"
     gene            8641..10104
                     /locus_tag="RPH49_000886"
     CDS             8641..10104
                     /locus_tag="RPH49_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001652331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDY5124069.1"
                     /translation="MNIDKQFWKTIYYWIRYLNFDIVSREKDDQEIWLAHKRKKQVVI
                     FKQHIKSTQEIRFDKAKVLEHKDEIANFISFEPQSFEFYYFTESEFSEEQLNEVSPIR
                     IKFNVIRHTKDLVKHMPNIFLARLISEDNDKKTYMFYKRKVLTDNFLDKYMQKFSPAT
                     YTIIFVNVLIWLCMILYLNNFSDVKLLDVGGLVHFNVVHGEWYRIVTSMFLHFSFEHI
                     LMNMLSLFIFGKIVEAIIGSWRMLTVYFIAGLFGNFVSLSFNTTTISVGASGAIFGLI
                     GSIFAMMYVSKTFNKKMLGQLLIALVILVGVSLFMSNINIVAHIGGFIGGLLITLIGY
                     YYKVNRNIFWILLIGMLVIFIALQIRIFTIKEDNIYNKLIKDDMTSGNYDNAQNIVKQ
                     TINKNYADDQTYYLSGMIMATINSKSEGMTEWERGLRMFPKSGLLNFELAIANRSLND
                     DEKALKYVRKALNTDPKNTDYINLEKELTKSNESKNK"
     gene            10085..10288
                     /locus_tag="RPH49_000887"
     CDS             10085..10288
                     /locus_tag="RPH49_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDY5124070.1"
                     /translation="MSRKINNFYDVQQLLKSYGFLIYFKNPEDMYEMIQQEISSLYQY
                     ELLSKEEYLKCTLIINQRRNEQK"
     gene            10285..11271
                     /locus_tag="RPH49_000888"
     CDS             10285..11271
                     /locus_tag="RPH49_000888"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDY5124071.1"
                     /translation="MTKIILAADVGGTTCKLGIFTPELEQLHKWSIHTDTSDSTGYTL
                     LKGIYDSFVEKVNENNYNFSNVLGVGIGVPGPVDFEKGTVNGAVNLYWPEKVNVREIF
                     EQFVDCPVYVDNDANIAALGEKHKGAGEGADDVVAITLGTGLGGGIISNGEIVHGHNG
                     SGAEIGHFRADFDQRFKCNCGRSGCIETVASATGVVNLVNFYYPKLTFRSSILELIKE
                     NKVTAKAVFDAAKAGDQFCIFITEKVANYIGYLCSIISVTSNPKYIVLGGGMSTAGPI
                     LIENIKTEYHNLTFTPAQFETEIVQAKLGNDAGITGAAGLIKTYVLDKEGVK"
     gene            11271..11600
                     /locus_tag="RPH49_000889"
     CDS             11271..11600
                     /locus_tag="RPH49_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MTH1187 family thiamine-binding protein"
                     /protein_id="HDY5124072.1"
                     /translation="MAIVDVVVIPVGTEGPSVSKYIADIQKKLQEYKAMGKIDFQLTP
                     MNTLIEGELSDVLEVVQVIHELPFDKGLSRVCTNIRIDDRRDKSRKMNDKLTSVQKHL
                     ENSGENL"
     gene            11597..12220
                     /locus_tag="RPH49_000890"
     CDS             11597..12220
                     /locus_tag="RPH49_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDY5124073.1"
                     /translation="MRISSLTLGLVDTNTYFIENDKAVILIDPSGESEKIIKKLNQIN
                     KPLKAILLTHAHFDHIGAVDDIVDRFDVPVYMHEAEFDFLKDPVKNGADKFKQYGLPI
                     ITSKVTPEKLNEGSTEIEGFKFNVLHTPGHSPGSLTYVFDEFAVVGDTLFNNGIGRTD
                     LYKGDYETLVDSILDKIFELEGDLPLFPGHGPYTTVDDEQLNPFLHG"
     gene            12272..13246
                     /locus_tag="RPH49_000891"
     CDS             12272..13246
                     /locus_tag="RPH49_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HDY5124074.1"
                     /translation="MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQ
                     IGNGIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHFNKIYFLRISTLPLSLGQESCVI
                     RIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
                     VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVI
                     QASLSGHLVLTTLHATDCKGAILRLLEMGVSVQELIQATNLIINQRLVTTIKQQRQLV
                     CEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTMDKYI"
     gene            13218..14288
                     /locus_tag="RPH49_000892"
     CDS             13218..14288
                     /locus_tag="RPH49_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HDY5124075.1"
                     /translation="MKLQWINTFKLHSKKRQLSKAQQIDLLLNLCNLLKYGFTLYQSF
                     QFLNLQMTYKNKQLGTTILSEISNGAPCNQILSLIGYSDTIVMQVYLAERFGNIIDVL
                     EETVNYMKVNRKSEQRLLKTLQYPLILVSIFIAMIIILNLTVIPQFQQLYTSMNIQLS
                     SFQKTLSFFITSLPTIIVVMLIIVSMLAIIMKLIYNKLNMLNKINFVMKLPLISGYFQ
                     LFKTYFVTNELVLFYKNGITLQSIVDVYINHSSDPFRQFLGKYLLTYSEMGYGLPQIL
                     EKLKCFKPQLIKFVLQGEKRGKLEVELKLYSQILVKQIEDKAIKQTQFLQPILFLILG
                     LFIVAIYLVIMLPMFQMMQSIK"
     gene            14302..14613
                     /locus_tag="RPH49_000893"
     CDS             14302..14613
                     /locus_tag="RPH49_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDY5124076.1"
                     /translation="MFKFLKKTQAFTLIEMLLVLLIISLLLILIIPNIAKQTAHIQST
                     GCNAQVKMVNSQIEAYALKHNRNPSSIEDLIADDFIKEAQKTCKSGETITISNGEAVA
                     N"
     gene            14591..15037
                     /locus_tag="RPH49_000894"
     CDS             14591..15037
                     /locus_tag="RPH49_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDY5124077.1"
                     /translation="MEKQLQIRKQSAFTMIEILVVMMLISIFLLLTMTSKGLSNLRVI
                     DDEANIISLITELNYIKSQAIANQGYINVRFYENSDTIKVIENNKIRFLKLKVGKIIN
                     VAKVDIIAFDKKGNINKFGSITIDNNNSIYRIIFHIEKGRIRYEKL"
     gene            15024..15323
                     /locus_tag="RPH49_000895"
     CDS             15024..15323
                     /locus_tag="RPH49_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGE"
                     /protein_id="HDY5124078.1"
                     /translation="MKSYKCKGSFLIDSMAGFLLIGLITLLLIPMMNQMQASINHKLQ
                     TIDASKVILTTVSKINKEELKKGVTIGKYDIKQSDQQICAISKNTTSYQKTCIQY"
     gene            15241..15738
                     /locus_tag="RPH49_000896"
     CDS             15241..15738
                     /locus_tag="RPH49_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDY5124079.1"
                     /translation="MILSKVTNKFVLFQKIPLLIKRHVYSINVKAFSLIEMLVAMMVI
                     SITLLIVPDLIRLSKTFLIESRELTTVDFEFFSRDILEDFRGVDRNDIEIRQQRIILH
                     KGEEMIEYKLINNKIIKVVNDRGNITMINNVTAFTANIYYKSIIKITITVKVGTNVQT
                     KTIYV"
     gene            15835..15981
                     /locus_tag="RPH49_000897"
     CDS             15835..15981
                     /locus_tag="RPH49_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124080.1"
                     /translation="MMLTAIYFSIFTFYISQYSLKLKTLYNIETDYNYKIVLLLKEGK
                     THES"
     gene            15971..16495
                     /locus_tag="RPH49_000898"
     CDS             15971..16495
                     /locus_tag="RPH49_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDY5124081.1"
                     /translation="MNHDKSPIILIGFMGTGKSTIGKYVADEQNLSFIDIDSYIEEKY
                     KLTIPEIFSKHGEQYFRNLEFTCLQECINTADIIATGGGIIESEEAFNFLKNQKNIIW
                     LDCNIDIIYSRINDDPHRPNANNKTIMQLNDLYCSRILRYNEIAFKKFDSHLLSISEI
                     YYELLNLIKASDQY"
     regulatory      16482..16579
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            16654..17745
                     /gene="gcvT"
                     /locus_tag="RPH49_000899"
     CDS             16654..17745
                     /gene="gcvT"
                     /locus_tag="RPH49_000899"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDY5124082.1"
                     /translation="MSSDLKQTPLYQNYVDRGAKIVEFGGWAMPVQFSSIKEEHNAVR
                     YEIGLFDVSHMGEIEVTGKDASQFVQYLLSNDTDNLTTSKALYTALCNEEGGIIDDLV
                     IYQLADDNYLLVVNAANTEKDFNWILKHKEKFDVEVQNVSNQYGQLAIQGPKARDLIN
                     QLVDEDVTEMKMFEFKQGVKLFGANVILSQSGYTGEDGFEIYCNIDDTEKIWDGLLEY
                     NVMPCGLGARDTLRLEAGLPLHGQDLTESITPYEGGIAFASKPLIDADFIGKSVLKDQ
                     KENGAPRRTVGLELLEKGIARTGYEVMDLDGNIIGEVTSGTQSPSSGKSIALAMIKRD
                     EFEMGKELLVQVRKRQLKAKIVKKNQIDK"
     gene            17765..19111
                     /gene="gcvPA"
                     /locus_tag="RPH49_000900"
     CDS             17765..19111
                     /gene="gcvPA"
                     /locus_tag="RPH49_000900"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPA"
                     /protein_id="HDY5124083.1"
                     /translation="MSHRYIPLTEKDKQEMLQTIGAKSIGELFGDVPSDILLNRDLNI
                     AEGEAETTLLRRLNRIASKNITKETHTSFLGAGVYDHYAPSVVDAMISRSEFYTAYTP
                     YQPEISQGELQAIFEFQTLICELTDMDVANSSMYDGMTSFAEACILAFSQTKKNKIVV
                     SKGLHYQALQVLHTYAKTRKEFEVVEIDLDGTVTDLKKLEAAVDDETAAVAVQYPNFY
                     GSIEDLEKIHSFIEDKKALFIVYANPLALGLLTPPGSFGADIVVGDTQPFGIPAQFGG
                     PHCGYFATTKKLMRKVPGRLVGQTQDDEGNRGFVLTLQAREQHIRRDKATSNICSNQA
                     LNALASSIAMSALGRQGIYDIAVQNIEHANYAKQQFIKKGFEVLDGTSFNEFVVKFDK
                     PIQQVNEELVKYNIIGGFDLGVVSDDFKNHMLIAVTELRTKDEIDTFVEKAGELND"
     gene            19104..20576
                     /gene="gcvPB"
                     /locus_tag="RPH49_000901"
     CDS             19104..20576
                     /gene="gcvPB"
                     /locus_tag="RPH49_000901"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase
                     subunit GcvPB"
                     /protein_id="HDY5124084.1"
                     /translation="MTSKSSPLIFERSREGRYAYSLPKSDIKTNSVESLLDDKFIRKN
                     KAEFPEVAELDLVRHYTELSNKNFGVDNGFYPLGSCTMKYNPKINEKVARIPGFSESH
                     PLQDEDQVQGSLEIIYSLQEELKEITGMDEVTLQPAAGAHGEWTALMIFKAYHENNGE
                     GHRDEVIVPDSAHGTNPASASFAGFKSVTVKSNERGEVDIDDLKRVVNENTAAIMLTN
                     PNTLGIFEKNIMEIREIVHNAGGLLYYDGANLNAIMDKVRPGDMGFDAVHLNLHKTFT
                     GPHGGGGPGSGPVGVVKELASYLPKPMVIKDGNKFKYDNDIKNSIGRVKPFYGNFGIY
                     LRAYTYIRTMGATGLKEVSEAAVLNANYIKARLSEHFEIPYKQYCKHEFVLSGVRQKE
                     FGVRTLDMAKRLLDFGVHPPTIYFPLNVEEGMMIEPTETESKETLDYFIDTLISIAEE
                     AKNDPDKVLEAPHTTVIDRLDEATAARKPILKFENLKQEK"
     gene            complement(20941..21327)
                     /locus_tag="RPH49_000902"
     CDS             complement(20941..21327)
                     /locus_tag="RPH49_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDY5124085.1"
                     /translation="MSASLYIAIILIIAIIAYMIVQQILNKRAVKELDQNEFHNGIRK
                     AQVIDVREKVDYDYGHINGSRNIPMTMFRQRFQGLRKDQPVYLCDANGIASYRAARIL
                     KKNGYTDIYMLKGGYKKWTGKIKSKK"
     gene            21485..22315
                     /locus_tag="RPH49_000903"
     CDS             21485..22315
                     /locus_tag="RPH49_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDY5124086.1"
                     /translation="MTETWNFINTGSKDPYYNMAMDEALLNFVSRGEIDPVIRFYTWN
                     PATLSIGYFQRLQKEIDIDKVKEKGFGLVRRQTGGRGVLHDKELTYSVIVPESHPNMP
                     STVTEAYRVISQGLLEGFKNLGFDTYFAVPKTPEERQKLKQPRSSVCFDAPSWYELVV
                     EGRKIAGSAQTRQKGVILQHGSILQDIDIDELFDMFIYKNERLKLKMKEAFVEKAVAI
                     NDISDKHITISQMEEAFEKGFKKGLNIELKPLELTEAQLAEVEELTEKYRSDEWMFRK
                     "
     gene            complement(22379..22597)
                     /locus_tag="RPH49_000904"
     CDS             complement(22379..22597)
                     /locus_tag="RPH49_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124087.1"
                     /translation="MRNIIFYLVLIIAAIGLVMNLDAFIFSIVRMLVSFAVIAGIIYL
                     IYYFFILTEDQRKYRKAMRKYKRNQRRK"
     gene            complement(22611..23192)
                     /locus_tag="RPH49_000905"
     CDS             complement(22611..23192)
                     /locus_tag="RPH49_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124088.1"
                     /translation="MKKLVSIVGATLLLAGCGSQNLAPLEEKTTDLREDNHQLKLDIQ
                     ELNQQISDSKSKIKGLEKDKENSKKTASNNTKIKLMNVTSTYYDKVAKALKSYNDIEK
                     DVSKNKGDKNVQSKLNQISNDIQSAHTSYKDAIDGLSLSDDDKKTSKNIDKLNSDLNH
                     AFDDIKNGYQNKDKKQLTKGQQALSKLNLNAKS"
     gene            23297..24358
                     /locus_tag="RPH49_000906"
     CDS             23297..24358
                     /locus_tag="RPH49_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDY5124089.1"
                     /translation="MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISK
                     DKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIKELLHQENFENVGFEGHHVSYDT
                     YLELNKSRISLISISNTVDKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEK
                     ELKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNG
                     YCSDITRTFAIGEPDPKLKEIYQIVLESQMKAINEIRPGMTGAEADAISRNYLESKGY
                     GKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILI
                     TENGCQVFTKCTKDLIVLT"
     gene            24384..24941
                     /gene="efp"
                     /locus_tag="RPH49_000907"
     CDS             24384..24941
                     /gene="efp"
                     /locus_tag="RPH49_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000626504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDY5124090.1"
                     /translation="MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNL
                     RTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNHVFMDNESFEQTELSSDYLKEEL
                     NYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTL
                     NVPLFVNEGDVLIINTGDGSYISRG"
     gene            25415..25879
                     /gene="accB"
                     /locus_tag="RPH49_000908"
     CDS             25415..25879
                     /gene="accB"
                     /locus_tag="RPH49_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDY5124091.1"
                     /translation="MNFKEIKELIEILDKSTLTEINIEDTKGKVTLKKEKETEIITPQ
                     ISQMPVEAAAMPMPQVQSTDSNKTEAPKPTSDNHKTINAPMVGTFYKSPSPDEEAYVQ
                     VGYTVSNETTVCILEAMKLFNEIQAEISGEIVEILVEDGQMVEYGQPLFKVK"
     gene            25879..27234
                     /gene="accC"
                     /locus_tag="RPH49_000909"
     CDS             25879..27234
                     /gene="accC"
                     /locus_tag="RPH49_000909"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDY5124092.1"
                     /translation="MKKVLIANRGEIAVRIIRACRDLGIQTVAIYSEGDKDALHTQIA
                     DEAYCVGPTLSKDSYLNIPNILSIATSTGCDGVHPGYGFLAENADFAELCEACQLKFI
                     GPSYQSIQKMGIKDVAKAEMIKANVPVVPGSDGLMKDVSEAKKIAQKIGYPVIIKATA
                     GGGGKGIRVARDEKELETGFRMTEQEAQTAFGNGGLYMEKFIENFRHIEIQIVGDSYG
                     NVIHLGERDCTIQRRMQKLVEEAPSPILDDETRREMGNAAVRAAKAVNYENAGTIEFI
                     YDLNDNKFYFMEMNTRIQVEHPVTEMVTGIDLVKLQLQVAMGEVLPYKQEDIKLTGHA
                     IEFRINAENPYKNFMPSPGKIEQYLAPGGYGVRIESACYTNYTIPPYYDSMVAKLIIH
                     EPTRDEAIMAGIRALSEFVVLGIDTTIPFHIKLLNNDIFRSGKFNTNFLEQNSIMNDE
                     G"
     gene            27249..27611
                     /locus_tag="RPH49_000910"
     CDS             27249..27611
                     /locus_tag="RPH49_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDY5124093.1"
                     /translation="MVKVTDYSNSKLGKVEIAPEVLSVIASIATSEVEGITGHFAELK
                     ETNLEKVSRKNLSRDLKIESKEDGIYIDVYCALKHGVNISKTANKIQTSIFNSISNMT
                     AIEPKQINIHITQIVIEK"
     gene            27671..28060
                     /gene="nusB"
                     /locus_tag="RPH49_000911"
     CDS             27671..28060
                     /gene="nusB"
                     /locus_tag="RPH49_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDY5124094.1"
                     /translation="MSRKESRVQAFQTLFQLEMKDSDLTINEAISFIKDDNPDLDFEF
                     IHWLVSGVKDHEPVLDETISPYLKDWTIARLLKTDRIILRMATYEILHSDTPAKVVMN
                     EAVELTKQFSDDDHYKFINGVLSNIKK"
     gene            28077..29414
                     /locus_tag="RPH49_000912"
     CDS             28077..29414
                     /locus_tag="RPH49_000912"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDY5124095.1"
                     /translation="MSDYLSVSALTKYIKYKFDQDPHLQSVLIKGELSNFKKHSSGHL
                     YFNVKDKESVISAMMFKGSASKLNFEPKEGDEVLLEARVSVFERRGNYQIYVNKMQLD
                     GIGNLYQKLEALKKKLTEEGCFDKANKKSIPKFPKKIAVLTASTGAAIRDIHSTINSR
                     FPLAEQIQISTLVQGEKAKDDIIEKIEYADSLGVDTIIVGRGGGSIEDLWNFNEEAVV
                     RAIYNCKTPIISAVGHETDFTLSDFAADIRAATPTQAAVIATPDQYELLQQIQQYQFT
                     LTRFIKKHLEQQRKHVEHLSSYYKFKQPTLLYDQQIQRRDDLEKRLKQQIQATFEQQR
                     HRLMLLQQRYNLKALLSSVNQEQQNNLQLTNQLVKLLNSKILSYKNDLKNKVENLNNL
                     SPTNTMLRGYAIVNKKDEVITSTKDLTENDQLTLTMKDGLVDAKVTKVRCNND"
     gene            29407..29637
                     /locus_tag="RPH49_000913"
     CDS             29407..29637
                     /locus_tag="RPH49_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDY5124096.1"
                     /translation="MTKETQSFEEMMQELEQIVQKLDNETVSLEESLDLYQRGMKLSA
                     ACDTTLKNAEKKVNDLIKEEAEDVKNDESTDE"
     gene            29615..30496
                     /locus_tag="RPH49_000914"
     CDS             29615..30496
                     /locus_tag="RPH49_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDY5124097.1"
                     /translation="MTNLPMNKLIDEVNNELSVAINKSVMDTQLEESMLYSLNAGGKR
                     IRPVLLLLTLDSLNTEYELGMKSAIALEMIHTYSLIHDDLPAMDNDDYRRGKLTNHKV
                     YGEWTAILAGDALLTKAFELISSDDRLTDEVKIKVLQRLSIASGHVGMVGGQMLDMQS
                     EGQPIDLETLEMIHKTKTGALLTFAVMSAADIANVDDATKEHLESYSYHLGMMFQIKD
                     DLLDCYGDEAKLGKKVGSDLENNKSTYVSLLGKDGAEDKLTYHRDAAVYELTQIDEQF
                     NTKHLLEIVDLFYSRDH"
     gene            30927..31379
                     /gene="argR"
                     /locus_tag="RPH49_000915"
     CDS             30927..31379
                     /gene="argR"
                     /locus_tag="RPH49_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDY5124098.1"
                     /translation="MPKKSVRHIKIREIISNEQIETQDELVKRLNDYDLNVTQATVSR
                     DIKELQLIKVPIPSGQYVYSLPNDRKFHPLEKLGRYLMDSFVNIDGTDNLLVLKTLPG
                     NAQSIGAILDQINWEEVLGTICGDDTCLIICRSKEASDEIKSRIFNLL"
     gene            31395..33074
                     /gene="recN"
                     /locus_tag="RPH49_000916"
     CDS             31395..33074
                     /gene="recN"
                     /locus_tag="RPH49_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDY5124099.1"
                     /translation="MLQTLSIKQFAIIEELEIQFSDGLTVLSGETGSGKSIIIDAIGQ
                     LIGMRASSDFVRHGEKKAVIEGIFDIDESKDAIHILKNMDIDVDEDFLLVKREIFSSG
                     KSLCKINNQTVTLQDLRKVMQELLDIHGQHETQSLLKQKYHLTLLDNYAESRYQDLLD
                     KYHQTFQNYKAKKQELEDLESADQALLQRLDLMKFQLEELSEAHLKEGEIEQLEIDIK
                     RIQNSEKLSLALNNAHMTLTDENAITDRLYELSNHLLTINDIVPNKYDKLKEDIDQFY
                     YILEDAKHELYDEMANTEFDEQVLNEYESRMNLLNNLKRKYGKDISELISYQEKLNNE
                     INKIENYEQSTSQLREEINALYNQVIEVGQALSKQRRIVARELRDHIVSEIQNLQMKD
                     ANLEISFKKLEEPNIDGIEFVEFLISPNKGEPLKSLNKIASGGELSRIMLALKSIFVK
                     SRGQTAILFDEVDSGVSGQAAQKMAEKMRDIAEYIQVICISHLPQVASMSDHHLLISK
                     SSKDDRTTTQVQELIGDDKVDEIARMISGASVTDLTRENAREMIQHNQRRR"
     gene            33225..34646
                     /gene="lpdA"
                     /locus_tag="RPH49_000917"
     CDS             33225..34646
                     /gene="lpdA"
                     /locus_tag="RPH49_000917"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDY5124100.1"
                     /translation="MSEKQYDLVVLGGGTAGYVAAIRASQLGKKVAIVERQLLGGTCL
                     HKGCIPTKSLLKSAEVFQTVKQAAMFGVDVKDANVNFENMLARKEDIINQMYQGVKHL
                     MQHNHIDIYNGTGRILGTSIFSPQSGTISVEYEDGESDLLPNQFVLIATGSSPAELPF
                     LSFDHDKILSSDDILSLKTLPSSIGIIGGGVIGMEFASLMIDLGVDVTVIEAGERILP
                     TESKQASQLLKKSLSARGVKFYEGIKLSENDINVNEDGVTFEISSDIIKVDKVLLSIG
                     RKPNTSDIGLNNTKIKLSTSGHILTNEFQQTEDKHIYAAGDCIGKLQLAHVGSKEGVV
                     AVDHMFEGNPIPVNYNMMPKCIYSQPEIASIGLNIEQAKAEGMKVKSFKVPFKAIGKA
                     VIDSHDANEGYSEMVIDQSTEEIVGINMIGPHVTELINEASLLQFMNGSALELGLTTH
                     AHPSISEVLMELGLKAESRAIHV"
     gene            34662..35654
                     /locus_tag="RPH49_000918"
     CDS             34662..35654
                     /locus_tag="RPH49_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HDY5124101.1"
                     /translation="MIDYKSLGLSEEDLKVIYKWMDLGRKIDERLWLLNRAGKIPFVV
                     SGQGQEATQIGMAYALEEGDITAPYYRDLAFVTYMGISAYDTFLSAFGKKDDVNSGGK
                     QMPSHFSSRAKNILSQSSPVATQIPHAVGAALAIKMDGKKKIATATVGEGSSNQGDFH
                     EGLNFAGVHKLPFVCVIINNKYAISVPDSLQYAAEKLSDRALGYGIHGEQVDGNDPLA
                     MYKAMKEARDRAISGQGSTLIEAVTSRMTAHSSDDDDQYRTKEEREALKKADCNEKFK
                     KELLSAGIIDDAWLAEIEAEHKDIINKATKAAEDAPYPSVEEAYAFVYEEGSLN"
     gene            35654..36637
                     /locus_tag="RPH49_000919"
     CDS             35654..36637
                     /locus_tag="RPH49_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDY5124102.1"
                     /translation="MAKLSYLEAIRQAQDLALQQNKDVFILGEDVGRKGGVFGTTQGL
                     QQKYGEDRVIDTPLAESNIVGTAIGAAMVGKRPIAEIQFADFILPATNQIISEAAKMR
                     YRSNNDWQCPLTIRAPFGGGVHGGLYHSQSIESIFASSPGLTIVIPSTPYDAKGLLLS
                     SIESNDPVLYFEHKKAYRFLKEEVPEEYYTVPLGKADVKREGEDLTVFCYGLMVNYCL
                     QAADILAADGINVEVVDLRTVYPLDKETIIDRAKHTGKVLLVTEDNLEGSIMSEVSAI
                     IAEHCLFDLDAPIMRLAAPDVPSMPFSPVLENEIMMNPEKILNKMRELAEF"
     gene            36650..37924
                     /locus_tag="RPH49_000920"
     CDS             36650..37924
                     /locus_tag="RPH49_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDY5124103.1"
                     /translation="MEITMPKLGESVHEGTIEQWLVSVGDHIDEYEPLCEVITDKVTA
                     EVPSTISGTITEILVEAGQTVAIDTIICKIETADEKTNETTEEIQANVDEHTQKSTKK
                     ASATVEQTSTAKQNQPRNNGRFSPVVFKLASEHDIDLSQVVGSGFEGRVTKKDIMSVI
                     ENGGTTAQSDKQVQTQSTSVDTSSNQSSEDNSENSTIPVNGVRKAIAQNMVNSVTEIP
                     HAWMMIEVDATNLVNTRNHYKNSFKNKEGYNLTFFAFFVKAVADALKAYPLLNSSWQG
                     NEIVLHKDINISIAVADENKLYVPVIKHADEKSIKGIAREINTLATKARNKQLTAEDM
                     QGGTFTVNNTGTFGSVSSMGIINHPQAAILQVESIVKKPVVINDMIAIRNMVNLCISI
                     DHRILDGLQTGKFMNHIKQRIEQYTLENTNIY"
     gene            38275..38712
                     /locus_tag="RPH49_000921"
     CDS             38275..38712
                     /locus_tag="RPH49_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA/BrxB family bacilliredoxin"
                     /protein_id="HDY5124104.1"
                     /translation="MDMNFDLYMNGVVEQARNEIESAGYEQLTTAEDVDKVLKQDGTT
                     LVMINSVCGCAGGIARPAASHALHYDVLPDRLVTVFAGQDKEATQRAREYFEGYAPSS
                     PSFALVKDGKITEMIERHQIEGHDVMNVINQLQTLFNKYCEER"
     gene            38726..39706
                     /locus_tag="RPH49_000922"
     CDS             38726..39706
                     /locus_tag="RPH49_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDY5124105.1"
                     /translation="MLKLNPYKIGFRTIKTAVGMTLGVIISKLLGLDNYASSAILVVL
                     CIKHTKVHSLQAIISRLVSCFLVLFLGSAIFSLLGQSPIVLGIIVLLFIPLTVVLKVQ
                     EGVITSCVILLHVFNAKSIDVHLIVNETLLLLIGLSIAFTMNLMMPSLDKQLDEYKCK
                     IEQQIADIFSKYSYICEKYEDTIAIEFEALLLNIKKAKSIAFRDVKNHFVRNENSYYH
                     YFDMREEQVELLMRMKPLIESICHKDPLLNDVASLLKEIGLNVNSNDYTAMRLHNLYE
                     TRLKLDELPLPTTHKALNSRASIIQILNELEEYLQIKSQFGSLKMHSEVA"
     gene            complement(39833..40012)
                     /gene="prli42"
                     /locus_tag="RPH49_000923"
     CDS             complement(39833..40012)
                     /gene="prli42"
                     /locus_tag="RPH49_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stressosome-associated protein Prli42"
                     /protein_id="HDY5124106.1"
                     /translation="MLVISSQVKSFISYVVIINTKVIHLEAHKMQNKVLRIIIIVMLV
                     SVVLALLLTSIIPIL"
     gene            40275..41408
                     /locus_tag="RPH49_000924"
     CDS             40275..41408
                     /locus_tag="RPH49_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HDY5124107.1"
                     /translation="MINEQRLLNTFLELVQIDSETGNESTIQPILKEKFIALGLDVKE
                     DEAAKHPKLGANNLVCTMNSTIEEGEVPKLYLTSHMDTVVPAINVKAIVKDDGYIYSD
                     GTTILGADDKAGLAAMLEVLQVIKEQQIPHGQIQFVITVGEESGLIGAKELNSELLDA
                     DFGYAIDASADVGTTVVGAPTQMLISAKIIGKTAHASTPKEGVSAINIAAKAISRMKL
                     GQVDEITTANIGKFHGGSATNIVADEVILEAEARSHDPERIKTQVKHMTDVFETTASE
                     LGGKAEVTVEQSYPGFKINDNEAVVKIAQESARNLGLSANTIISGGGSDGSIINTFGI
                     PSVILGVGYEKIHTTNERMPIKSLNLLASQVLEIIKIVARQSK"
     gene            41476..42882
                     /gene="gndA"
                     /locus_tag="RPH49_000925"
     CDS             41476..42882
                     /gene="gndA"
                     /locus_tag="RPH49_000925"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDY5124108.1"
                     /translation="MTQQIGVIGLAVMGKNLAWNIESRGYSVSVFNRSSEKTDLMVEE
                     SKGKNIHPTYSLEEFVNSLEKPRKILLMVQAGKATDATIDSLLPLLDDGDILIDGGNT
                     NYQDTIRRNKALAQSAINFIGMGVSGGEIGALTGPSLMPGGQEEAYNKVADILDAIAA
                     KAKDGASCVTYIGPNGAGHYVKMVHNGIEYADMQLIAESYAMMKELLGMSHEDIAQTF
                     KDWNAGELESYLIEITGDIFMKLDENKEALVEKILDTAGQKGTGKWTSINALELGIPL
                     TIITESVFARFISSIKEERVNASKELNGPKASFDGDKKDFLEKIRKALYMSKICSYAQ
                     GFAQMRKASEDNEWNLKLGDLAMIWREGCIIRAQFLQKIKDAYDNNPGLQNLLLDPYF
                     KNIVTEYQDALRDVVATGVQNGVPTPGFSSSINYYDSYRAADLPANLIQAQRDYFGAH
                     TYERKDKEGVFHTQWIEE"
BASE COUNT        15831 a         5738 c         7904 g        13421 t
ORIGIN      
        1 ttgaaatttc gaggttttaa tatttttatt taaaatagca catttatact ttataatagt
       61 aaagatgaac atataaggag gccaaatcat ggcaaaacat ccattcgaac aatttaatct
      121 agaatctagt ttaattgacg ctgtgaaaga ccttaatttt gaaaaaccaa ctgaaattca
      181 gaatcgaatt attccaagaa tactaaagag aacaaattta attggtcaat ctcaaacggg
      241 tacagggaaa tctcatgcat ttttattacc attaatgcag ttaattgata gtgaaataaa
      301 agaaccacaa gcaatcgtag ttgcaccaac aagagaactt gcacaacaac tatacgatgc
      361 agcgaaccat ttaagccaat ttaaagctgg cgtttcagtt aaagttttta ttggtggtac
      421 agatatagag aaagatagac aacgttgtaa tgcacaacca caattgatta taggcacccc
      481 tactagaatt aatgacttag ctaaaacggg acatttacat gtgcacttag catcatattt
      541 agttattgat gaagcggatc ttatgattga cttaggatta attgaagatg tagattacat
      601 tgctgcaaga ttggaagata atgcaaatat tgcggtgttt agtgctacaa ttccacaaca
      661 gttacaacca tttttaaata aatatttaag tcatccagaa tatgtagctg tcgacagtaa
      721 aaaacaaaat aaaaagaaca tcgaattctt tttaatacct actaaaggtg cagctaaagt
      781 tgaaaagact ttaaatttaa ttgatatact aaatccatac ttatgtatta ttttctgtaa
      841 tagtagagat aatgcaaatg atttagcacg ttcactaaat gaagctggta ttaaagttgg
      901 tatgattcat ggtggtttaa cgccacgtga acgtaaacaa caaatgaaac gtatacgtaa
      961 tttagaattc caatacgtta ttgccagcga tttagcatct cgtggtattg atattgaagg
     1021 tgttagtcat gtcatcaatt ttgatgtgcc aaatgatatt gacttcttta cacatagagt
     1081 cggacgaact ggtcgtggga attataaagg tgtagcaata acgctttata gtcctgatga
     1141 agaacacaat atttcattaa tagaaaatcg cggttttgtt ttcaatactg ttgatattaa
     1201 agatggtgag ttaaaagaag ttaaagcgca caatcagcgt caagcaagaa tgcgcaaaga
     1261 tgaccattta actaatcaag tgaagaacaa agttcgaagt aaaattaaaa acaaagttaa
     1321 accaggttat aagaagaaat ttaagcaaga agttgaaaaa atgaaacgtc aagagcgtaa
     1381 acaatttagt aagcagcaaa atagacaaaa acgtaagcaa aacaaaaaag gttaggtgtg
     1441 ttttatgtta ttaggatcac atgtttcaat gagtggtaaa aagatgttag aaggttctgc
     1501 tatagaagcg catgaatatg gtgaaacaac atttatgatt tatactggtg cacctcaaaa
     1561 tacgcgccgt aaaagtattg aagatttaaa tataactaaa ggtcatgaag tgatggaaaa
     1621 atatggctta tctaatattg ttgttcatgc accatacatc attaatattg caaatacaac
     1681 caaaccagaa acgtttaatc ttggtgtaga tttcttgcaa caagaaattg aaagaacgca
     1741 agctataggc gctaaagata ttgtattaca tccaggtgcg catgttggag ctggtgttga
     1801 tgccggaatt aataagatta ttgaaggatt aaatgaagtt ttaacgaatg acaataatgt
     1861 acgtattgcg cttgaaacga tggcaggtaa aggtactgag attggtcgct cgtttgaaga
     1921 gttagcacgt attattgatg gagttcataa taacgaacgt ttatcagtat gttttgatac
     1981 atgtcatacg catgatgctg gatataatgt gaaagaggac tttgatggcg tattaaatga
     2041 atttgataaa atcattggag tcgacagaat caaagttgtt catgtcaatg attctaaaaa
     2101 tgaccgtggc gctcaaaaag accgacatga aaatattggc ttcggttaca ttggttttga
     2161 tgcattaaat tacattgtgc atcatgatag ttttaaagat attccgaaaa tcttagaaac
     2221 accttatgtt ggtgaagata agaaaaataa aaaaccgcca tataaacttg aaattgaaat
     2281 gttgaaacaa cagcaatttg acccagaatt aaaaaataag gttatgcaac aataaaatga
     2341 taatgctctc ttcaagaaat gcgataaata aaacttgaag ggggcatatc tctttatttt
     2401 gtcttatttt gagtcgtaaa cattactgtt tacatatgtt actaggagtt gtatagttga
     2461 atgcgaggtg agaatacgat gacaccagtc tttgaattga agaatgtcaa ttactactat
     2521 gatcataaaa aagtgttaga aaatataaac attaaaataa ataaaggtga atttttagca
     2581 attgttggac caaatggtgc tggtaaatca acattattga agttgattct aggattatta
     2641 cctttacaaa gtggtgagat ttttgttgaa ggtattgatt ttaaaaataa gaaaacatca
     2701 attaaattaa gctatgtatc acaaaaagca aatgccttta attcaggttt cccagcaagt
     2761 gttaaagaag ttgttttaag cggattaaca aagacaaaac gtcttttcca aacatttaat
     2821 agcaaagata atgaaaaagt gattaaagta ctagaaagac tgaatataag tgatttaatt
     2881 cataaaaata tagcagaatt atcaggtggt caacaacaac gtgtaatgat tgctcgagca
     2941 ttgatttcag aacctgcagt attagtactt gatgaaccga cgaatggtat tgatgcaaaa
     3001 catgtaagtg aattttataa tactttagat caattaaaac aagaaggtat cactattatc
     3061 ttagttactc atgatattgg tgttgtagca gatactgcta ctgaagtagc atgtttaaat
     3121 aagcatttgc atttccatgg tacaactgat gagtttaaat cacttgatga agttgaaatt
     3181 tcaaaaattt atggacatcc tgtacgtttt gtcgatcatc agcataatcg agaatgttgt
     3241 aattaataaa gatttgagtt tatataaaat ggaaaggcgt gtcacaattg atagatgcat
     3301 tattgaattt tgattttatg aggtactctt taattagtgg tatcttgata ggttttattg
     3361 cgcctctaat cggtgctttt atcgttgtta gacgactatc acttatagct gatgctctaa
     3421 gtcatgtaac tttaggtggt atatccttcg gtatgttttt acttactatt atgccaacac
     3481 tagtatttat taatccaatg tggtttggaa tcttattcgc aatagtaggt gcgcttctaa
     3541 ttgaaaaatt aagaacgtca tacactgctt accaagaaat tgctattcca attataatga
     3601 gtgctggtat cgccttgagt gcaatcttca tttcattagc tgatgggttc aatcaagaaa
     3661 ttgttggatt gctatttggc tcaataagcg cagtgaatat aagtgattta acaacgatta
     3721 ttgtcattgc catcatagtt gttctgttta ttacattgtt ttataaagaa ttatttatat
     3781 tgtcatttga tgaggaatat agtaaagtca ttggcattcc taaatggatt caatttttat
     3841 ttattgttat tgtagcgatg gttatttctg cctcaatgcg tgttgtaggg atactgttag
     3901 taagtgcgtt aatcacgtta ccaattgcaa taagtatgcg aataacaaaa agttttaagc
     3961 aattgatatt actaagtgta tttttaggtg aattatcagt aatattaggc ttagtcctag
     4021 ctttctatat ggacatttct ccgggtggtg taattgtagt tctactggtt attttactta
     4081 tgattacaat ggcttatcag aaaatgcgaa tgaagtttaa aaagggagct aatatcaatg
     4141 aatacaaatg atgctattaa aattttaaaa gagaacggtt taaaatatac agataaacgt
     4201 aaagatatgt tagatatttt tgtcgaagaa gataagtata taaacgcaaa gtatatacaa
     4261 caagttatgg atgaaaatta tcctggaatt tcattcgaca caatatatag aaacctgcac
     4321 ttatttaaag atttagggat tattgaaaat acagaacttg atggtgaaat gaaatttaga
     4381 atcgcttgta caaaccatca tcatcatcat tttatctgtg aaaagtgtgg agatacaaag
     4441 gtaatagatt attgtccaat agatcagata aaattatcac tacctggtgt taatattcac
     4501 aaacacaaac ttgaagttta tggtgtatgt gagtcttgcc aagattaata taaagaaatg
     4561 agatttatac acattaggtc agatgtatgc ataaatctca ttttttaaat tatagaagat
     4621 aaaggttcat ttcatactcc gttcgtatga ttttatggca aatctgttaa ctttttatat
     4681 acaaaatgtt taattatttt tgatttgagt tatattaaat gagtagagaa aataataagt
     4741 agtagtattt aagcaaattc tttgttgaac cagtcactgc ttgttattat ttacttacag
     4801 acattttagg aggatgatta tttatggctt ttgaattacc aaaattacca tacgcatttg
     4861 atgcattaga accacatttt gacaaagaaa ctatggaaat tcaccatgac agacatcata
     4921 acacttatgt tacgaaatta aatgctgcag tagaaggtac agatttagaa tctaaatcta
     4981 ttgaagaaat tgttgctaat ttagacagtg taccagctaa catccaaact gctgtacgta
     5041 ataatggcgg tggacattta aaccattcat tattctggga gttactttca ccaaactcag
     5101 aagaaaaagg tactgttgta gaaaaaatta aagaacaatg gggttcttta gaagaattta
     5161 aaaaagaatt tgctgacaaa gcagctgcac gctttggttc aggttgggct tggttagtcg
     5221 taaacaatgg ccagttagaa attgtgacta caccaaacca agataatcca ttaactgagg
     5281 gtaaaacacc tattttaggt ttagacgtat gggaacacgc ttattaccta aaatatcaaa
     5341 acaaacgccc tgactacatt ggcgcatttt ggaatgtagt taactgggaa aaagttgacg
     5401 aattatataa tgcaacaaaa taaagtatga ttacttgttc ggtctcttaa atgagaccgt
     5461 tatttttttg tcaaaaagat agaaataatt tctaaattca tatatgattt aaagtgaaag
     5521 actttgaata gaggtaggta gttttgttaa aaagactaaa agaaaaatca aatgatgaaa
     5581 tcgttcaaaa tacaattaac aagagaatta actttatatt tggtgtgatt gtatttattt
     5641 ttgcagtact agtactacgt ttaggttatt tacaaatcgc acaaggctca cattataaac
     5701 aaattataaa aaatgatgaa aacattacag tgaatgagtc tgtgccaaga ggtcgtattt
     5761 tagacagaaa tgggaaagtt ttagttgata atgcttctaa aatggctatt acatatacta
     5821 ggggtcgaaa aacaacacaa tcggaaatgt tggatacggc tgaaaagtta tcaaagctaa
     5881 tcaagatgga tactaagaag attacagaac gtgataaaaa agatttctgg attcagttgc
     5941 atcctaaaaa agcaaaagca atgatgacaa aagaacaagc tatgttagca gatggaagta
     6001 ttaaacaaga tcaatatgat aaacaactgt tatcgaaaat cggaaaatca caattagatg
     6061 aattgtcttc taaagattta caagttttag ccatttttcg agagatgaat gcaggaacag
     6121 ttttagatcc acaaatgata aaaaatgaag atgtcagtga aaaagagtat gcagcagttt
     6181 ctcagcaact ttccaaatta ccaggtgtta acacgtctat ggattgggat agaaaatatc
     6241 catatggcga cacattaaga ggtatattcg gagatgtatc gacacctgct gaaggtattc
     6301 caaaagaatt gacagaacat tacttatcca aaggatattc acgcaatgat cgtgttggaa
     6361 aatcttacct agaatatcaa tatgaagatg tattgcgtgg taagaagaaa gaaatgaaat
     6421 acacaacgga caaatctggt aaagttacat cttcagaagt gttaaatcct ggcgctcgcg
     6481 gtcaagattt gaaattaacg atcgatatag atcttcaaaa agaagtagaa gcattattag
     6541 ataaacaaat taagaagctt cgcagccaag gtgcaaaaga tatggataat gctatgatgg
     6601 ttgtacaaaa tcctaaaaat ggagacattc ttgcgcttgc cggaaagcag attaataaga
     6661 gtggtaaaat gactgattat gacattggta cgtttacttc tcaatttgca gttggatctt
     6721 ctgtaaaagg tggaacatta ttagctggtt atcagaataa agctatcaaa gttggagaaa
     6781 caatggtcga tgaaccatta catttccaag gtggtttgac aaaacgatca tactttaata
     6841 aaaacgggca tgtatctatt aatgataagc aagctttgat gcattcatca aacgtatata
     6901 tgtttaaaac agcattaaaa ttagcgggag acccttatta ttctggtatg gctttaccat
     6961 cagacataag ttcacctgcc caaaagctaa gaagaggatt gaatcaagta ggcttaggtg
     7021 tgaaaacagg tatagattta ccaaatgaaa caaaaggtca aatcgaacca ttaacaaata
     7081 atccaggtaa ttatctagat ttatcaattg gtcaatatga tacctataca ccattacaat
     7141 tatcacaata tgtttcaact atagcgaatg atggttatag aatacaacca cacattggat
     7201 taacgattca tgaatcaact aataaagatg aggttggtcc actcaagaag aaaattaatg
     7261 gcaccgtctt gaacaaagtt aataatactg aaaatgaaat caaacaaatt caagaagggt
     7321 tcaaaatggc gtttaatgat aaagatggta ctggatatgt tagttttaaa gatacagtag
     7381 tgcctactgc tggtaaaact ggtaccgctg aagtgttcca aaacggagag ccaagagtta
     7441 actctactta tataggatac gcgccaattg atgatccaaa attagcgttt tcaattgtat
     7501 atacaaatca gcctgtacca ccaccatggt taacaggtgg agacttaggt agagatgtaa
     7561 ttaactacta ctttaagcag ttaggtaaag atgataaaaa taaagataaa gataaataaa
     7621 atttaacctg acgattgtgt agcgcatggt tgtaaaattt taactttgca aatattatag
     7681 atgttggtat aataataaag tcgtatttag aaatgataag gaggaataac catgcgcgta
     7741 aacgtaactt tagcttgtac ggaatgtggt gacagaaact acattacaac taagaacaaa
     7801 agaaataatc cagaacgtgt tgaaatgaag aaattctgtt cacgtgaaaa caaacaaact
     7861 ttacaccgtg aaacaaaata atcattaaaa ttaaatttaa attaacaata aaaaaggtga
     7921 aatctcaaaa taagaggttt caccttttta attgtgcaca cgtatgaaat gataaaagat
     7981 tttcaattga aataataaat tttagaattg tcgcataatt catcatgaca acataatgac
     8041 atgtattgtt attaacgata taatagaatt gaataaagtg ggtgataatg tgactaaaaa
     8101 tgagattaga aaatacattt tacataaaat gaagaatttt aataaggctg aaaagcgaaa
     8161 agcagacaca tggttaagaa atcaattttt tgcaactgaa gaatataaag aagcaaacgc
     8221 aattgcgcta gttctttctt ttaatcatga agtagatact ttttctatta ttgaacaagc
     8281 cttaatggat cataaacgta tttttgtacc gaaaatggat tatttaaatc atcaaatgac
     8341 ttttaaagag atatttaatc tcaaagatat tgatgtcgat aataaggggg tttactatcc
     8401 aacttcaaaa ggtgaaacaa cgaataacct agatttaatt gttgttcctg gtgttggatt
     8461 tcaagacgat ggatatagaa ttgggtatgg tggtggctat tacgacaggt ttttagctaa
     8521 ttatcagaca aagacaataa gcttattata cgattttcaa ataacatcat ttgaaccgga
     8581 atcattcgat caaccagtcg ataaattgat tatatatcaa tcagcatagt ggaggactaa
     8641 atgaacatag acaaacaatt ttggaaaaca atatattatt ggattaggta cttgaatttt
     8701 gatattgtca gtagggaaaa agatgaccaa gaaatttggt tagcccataa aagaaaaaaa
     8761 caagtagtca tttttaaaca acatatcaag tctacccaag aaatacgttt tgacaaagcg
     8821 aaagtgcttg aacacaaaga tgaaatagca aattttattt ctttcgaacc acaaagtttt
     8881 gaattttatt attttacaga atcggaattt tcagaagaac aattaaatga agtttcgcca
     8941 attagaatta aattcaatgt tataagacac acaaaagatt tggtaaagca tatgccgaat
     9001 atatttttgg ctagacttat ttcagaagat aatgataaaa agacatatat gttctataaa
     9061 cgcaaagtat taaccgataa ctttttagat aaatatatgc agaaattttc accggcaaca
     9121 tacacaataa tatttgtaaa tgtcttaata tggttatgta tgattttata tttaaataat
     9181 ttttcggatg taaaattatt agatgttggc gggttagtgc attttaatgt cgtacatggt
     9241 gaatggtatc gaattgttac atcgatgttt ttacatttta gttttgaaca tatacttatg
     9301 aatatgcttt cattatttat ttttggtaaa atagtcgaag caattattgg ttcatggcgg
     9361 atgttaactg tatactttat tgcagggttg tttggaaact ttgtatcact atcatttaat
     9421 acgactacaa tttcagttgg ggctagtggt gctatatttg gtctgattgg atcaattttt
     9481 gcgatgatgt atgtttcaaa aacatttaac aaaaaaatgt tagggcagtt attaattgca
     9541 ttagtgatat tagttggtgt ttctctgttt atgtcaaata taaatattgt ggcgcatatt
     9601 ggaggattca ttggtggttt attaataact ttaattggct attactataa agtgaatcgt
     9661 aatatttttt ggattttact aattggtatg cttgttatat ttattgcact tcaaattaga
     9721 atttttacaa ttaaagaaga taatatttat aataaattga tcaaagatga tatgactagt
     9781 ggtaattatg ataatgctca aaatattgtg aagcagacaa taaataaaaa ttatgccgat
     9841 gatcaaacat attatttaag tggtatgatt atggctacta tcaattctaa gtctgaaggt
     9901 atgacagaat gggagcgagg acttagaatg tttcctaaat caggtttatt aaattttgag
     9961 ttagcgatag caaatcgttc attaaatgat gatgaaaaag cattaaaata tgtgcgtaaa
    10021 gcattaaata cagaccctaa aaatacagat tatattaact tagaaaaaga gttgactaaa
    10081 tcaaatgagt cgaaaaataa ataactttta tgatgtacaa cagttattga aaagttacgg
    10141 ttttctaata tattttaaaa atccagaaga tatgtacgaa atgattcaac aggagatttc
    10201 atcattgtat caatatgaac tgttatctaa ggaagaatat ttgaaatgta cgttgataat
    10261 taatcagaga aggaatgaac agaaatgaca aaaattattt tagcagctga tgtaggcggg
    10321 acgacttgta aattaggtat tttcacacct gaattagaac aattacataa atggtctatt
    10381 cacactgata catctgatag tacaggatat acacttttga aaggaattta tgattcgttt
    10441 gttgaaaaag taaatgaaaa taattataat ttttcaaatg tacttggcgt aggtattggt
    10501 gttccaggtc ctgttgactt tgaaaaaggt acagtaaatg gagcagtaaa cttatattgg
    10561 ccagaaaaag ttaatgtacg tgagattttt gaacaattcg ttgattgtcc agtgtatgta
    10621 gataatgatg ctaacatagc tgctttaggg gagaaacaca aaggtgctgg tgaaggtgcc
    10681 gatgatgttg ttgccatcac acttggtaca ggtctaggtg gaggaattat ttcaaatggt
    10741 gaaatcgtac atggtcataa tggctctggc gcagaaatag gtcattttag agcagacttc
    10801 gatcaacgat ttaaatgtaa ttgtggtcgt tctggatgta ttgaaacagt tgcttcagcg
    10861 acaggcgttg ttaacttagt taacttctac tatccgaagt tgacgtttag atcttctata
    10921 ttagaattga ttaaagaaaa taaggttaca gcaaaagctg tttttgatgc ggcaaaagct
    10981 ggtgaccaat tctgtatttt cattactgaa aaggttgcaa actatattgg atatttatgt
    11041 agtattatta gtgttacaag taatccgaaa tatatcgttt taggtggagg aatgtctact
    11101 gcaggaccta ttttaattga aaatattaaa acagaatatc ataatttaac atttacacct
    11161 gctcaatttg aaactgaaat tgttcaagcg aaattaggta atgatgcagg tattacagga
    11221 gcagcaggat taatcaagac ctatgtatta gataaagagg gggtaaaata atggctattg
    11281 ttgatgtggt tgttattcca gttggaacgg aaggtccgag tgttagtaaa tatattgcag
    11341 atattcagaa aaaacttcaa gaatataaag cgatgggtaa aattgacttt caattaacac
    11401 caatgaatac tctaattgaa ggtgaattaa gcgatgtatt agaagttgtg caagtgatac
    11461 atgaattacc ttttgataaa ggtttaagta gagtttgtac aaatatccgt attgatgacc
    11521 gacgagacaa atctagaaaa atgaatgata aactaacatc agtacaaaaa catttagaaa
    11581 atagtggtga aaacctatga ggatttcaag cttaacttta ggcttagttg atactaatac
    11641 gtatttcatc gaaaatgaca aagctgttat tctgattgac ccttcaggtg aaagtgaaaa
    11701 aattattaaa aaattaaacc aaataaataa accgttaaaa gctattttat taacacatgc
    11761 acactttgat catatcggag cagtcgatga tatagttgat cgattcgatg tcccggttta
    11821 tatgcatgaa gcagagtttg attttctaaa agatcccgtt aaaaatgggg cagataaatt
    11881 taagcaatat ggattaccaa ttattacaag taaggtaact cctgaaaagt taaacgaagg
    11941 tagcacagaa atagaaggat ttaagtttaa tgtgttacac acacctggac attcaccagg
    12001 aagtttaaca tatgtgttcg atgaattcgc agttgttgga gatacattat ttaataatgg
    12061 aattggacgt acagatttat ataaaggtga ttatgaaact ctagttgatt ctattctaga
    12121 taaaatattt gaattagaag gcgatttacc tttattccct ggacatggtc catatacgac
    12181 ggttgatgat gaacaattaa atccattttt acatggttaa attgaagtaa taaaaacacc
    12241 tcctacgtga ttatatgtag gaggtgtttt tttgaagatt ctatttcaag aaataattaa
    12301 taaagcgata gaaatgaaag cgagtgatgt acattttatt ccagttaaaa atgaagtaag
    12361 tattaaattt agaattaatg ataacttgga gcagtatgaa caaattggga atggcattta
    12421 tcaaaagtta ttagtttata tgaagtttca agctgggctt gatgtttcta cacagcaagt
    12481 cgcacagagc ggtcgatata gttaccattt caataaaatt tattttttga gaatatcaac
    12541 attaccattg tcacttggcc aagaaagttg tgttatcaga attgtacctc aattttttca
    12601 acaacagaaa tcaacttata aattcaatga ttttaaacac ctcatgaaca agaaacaagg
    12661 attactattg tttagtggac caactggttc aggaaagagt acattaatgt atcaaatggt
    12721 ctcatacgcg aataaagcct tgaatttaaa tgtaatttct atagaggatc ctgtagagat
    12781 gcaaattcct ggtattgttc aaattaatgt gaatgataaa gctggcatta actatgtaaa
    12841 ttcgtttaaa gctattttaa gatgtgatcc cgatgttatt ttaataggtg aaatcagaga
    12901 taaagatgtt gccaagtgtg ttatacaggc tagtttaagt ggtcaccttg ttctgactac
    12961 attgcatgca actgattgta aaggtgctat tttaaggcta ttagaaatgg gtgtttctgt
    13021 acaagaattg atacaggcaa ctaacttaat tataaaccaa cgacttgtaa ctactattaa
    13081 gcaacagcga caattagtat gtgaaattct atctcagcaa caactccgat atttcttttc
    13141 ccataatcat tcattaccat catcatttaa gaacttagaa gataaacttg atgatatgac
    13201 aaaagcaggt gtcatttgtg aaactacaat ggataaatac atttaaacta cattctaaga
    13261 agcgacaatt aagtaaggcc caacaaatcg atttactttt aaatttatgt aatttgttga
    13321 aatatggttt cactctgtat caaagttttc aatttttaaa tcttcaaatg acatataaaa
    13381 ataagcaatt aggcaccacc attctaagtg aaatttcaaa tggtgcacca tgcaaccaga
    13441 tattatcact gataggttat agcgatacta tcgtcatgca agtatatttg gcagaaagat
    13501 ttggcaatat catagacgtt ctagaagaaa ccgtaaatta tatgaaagtg aatagaaagt
    13561 cagaacaacg attgttaaag acactgcaat accccttaat actagtttcg atttttattg
    13621 ctatgattat tatattaaac ctcacagtaa ttccacagtt tcaacaatta tatacttcta
    13681 tgaatattca actatcttct tttcaaaaaa cattgtcttt tttcattacc agcttaccta
    13741 ctataattgt agtaatgctc ataatagtat ctatgttggc tattattatg aaattaattt
    13801 ataacaaatt aaatatgctc aataagataa actttgtgat gaaactaccg ctaatatcgg
    13861 gctatttcca attatttaaa acttattttg taactaatga attagtgtta ttttataaaa
    13921 atggtattac acttcaatca atagtagacg tttatattaa ccatagtagt gatccattta
    13981 gacagtttct aggtaaatac ttattaactt attcagaaat gggatatggt ttacctcaaa
    14041 ttttagaaaa actaaaatgc tttaagcctc aattaattaa gtttgtgcta caaggtgaaa
    14101 agagaggaaa gctagaagta gaactaaagt tatattcgca aatattagta aaacaaatag
    14161 aagataaagc gataaaacag actcagtttt tacagcctat tttatttttg attttaggtt
    14221 tatttattgt cgcaatttat ttggtaatta tgttaccaat gtttcaaatg atgcaaagta
    14281 taaaataatg gaggttaata tatgtttaaa tttcttaaga aaactcaagc gtttacattg
    14341 atagagatgc tattagtgtt attaatcatc agtttattat taattttaat cattccaaat
    14401 attgctaaac aaactgctca catacaatca acaggttgta atgcacaggt aaaaatggtt
    14461 aatagtcaaa ttgaagcgta tgcattgaaa cataatagaa atccatcgtc tattgaagac
    14521 ttaattgcag atgattttat aaaagaagca caaaagacat gtaaatcagg agagacaatc
    14581 acaattagta atggagaagc agttgcaaat tagaaagcag tcagcattta ctatgattga
    14641 gatacttgtg gtaatgatgt taatcagtat atttttactt ttgacaatga catctaaagg
    14701 attaagcaat cttagagtaa tagatgacga ggcaaatatc atttctctta ttactgaatt
    14761 gaattatatt aaatcgcaag ctatagcaaa tcaaggatat atcaatgtta gattttatga
    14821 aaacagtgac actattaaag taatagagaa taataaaata cgatttctaa aattaaaagt
    14881 aggcaaaata attaatgttg caaaagttga tattattgcc tttgataaaa aagggaatat
    14941 caataaattt ggtagcataa caattgacaa taacaattca atttatagaa taatattcca
    15001 tattgaaaaa ggaagaattc gttatgaaaa gctataagtg taaaggatca ttcttaatag
    15061 atagtatggc tggatttttg ctaattggat tgattacatt actattgata ccaatgatga
    15121 atcaaatgca agcgagtata aaccataaac tacaaacaat tgatgcttct aaagtaattt
    15181 tgacgactgt atctaaaatt aataaagaag aacttaagaa gggggtaact atagggaaat
    15241 atgatattaa gcaaagtgac caacaaattt gtgctatttc aaaaaatacc acttcttatc
    15301 aaaagacatg tatacagtat taatgtcaaa gctttttcgc ttattgaaat gttagtagcg
    15361 atgatggtta taagtataac tttactaatt gttccagact taattagact tagcaaaact
    15421 tttctaattg aaagtaggga attaacaact gtagatttcg aatttttctc aagagatatt
    15481 ctagaggatt ttagaggtgt agatagaaac gatattgaaa ttaggcaaca gcgtatcatt
    15541 ttacataaag gtgaagaaat gatcgaatac aaattaataa ataataaaat tattaaagtt
    15601 gtaaatgaca gaggaaatat aacaatgatt aataatgtta cagcatttac tgcaaatatc
    15661 tactataaat ctattattaa aataacgata acagttaaag tcggtacaaa tgtgcagact
    15721 aaaactattt atgtataact tactagaatt taaatgagta ctattaaaaa ggatgtgaaa
    15781 taatttatta attttgattt atataaagaa aaaggatatg ttacgccgtt cttattgatg
    15841 ctaacagcaa tttatttttc cattttcact ttttatatca gtcaatatag tttaaaatta
    15901 aagacattat ataatattga aactgactat aactataaga ttgttttgtt attgaaagaa
    15961 gggaaaacgc atgaatcatg ataaatcacc aataatttta attggtttca tgggtaccgg
    16021 taaatctacg attggtaaat acgttgcaga tgagcaaaat ttatcattta ttgatataga
    16081 ttcatatatc gaagaaaagt ataagttaac aataccagaa atatttagta aacatggtga
    16141 acaatatttc aggaatttag agttcacatg tttgcaagaa tgtattaaca ctgcagatat
    16201 aattgctact ggtggtggta ttattgaaag tgaagaggca tttaattttt tgaaaaatca
    16261 aaaaaacatt atttggttag attgtaatat tgatattata tatagtcgaa tcaatgatga
    16321 cccacatcga cctaatgcaa ataataagac aatcatgcag ttaaatgact tgtattgctc
    16381 gcggatttta agatataatg aaatcgcatt caagaaattt gatagtcatt tgctatcaat
    16441 ttcagaaata tattatgaat tgctaaattt aataaaagcg agtgatcagt attagagaga
    16501 atagagcgtt aagactctat cgccgaaggt gcaagtaatt tattacgaaa ctctcaggca
    16561 aaaggataat actgtaacgc gttcctgaat tggtgattta taaacagggt agcgattgct
    16621 atcctgtttt tataatttta agggggtatt tcaatgtcaa gtgatttaaa acaaacacct
    16681 ttatatcaaa attatgttga tagaggtgca aaaattgtgg aattcggagg atgggcgatg
    16741 cctgttcaat tttctagtat taaagaggaa cataatgctg ttcgatacga aataggcctg
    16801 tttgatgtta gtcatatggg tgaaattgaa gtaacaggta aagatgctag tcagtttgtg
    16861 caatatttat tatcaaatga tactgataat ttaactactt caaaagcatt atatactgct
    16921 ttatgtaatg aagaaggcgg tattattgat gatttagtaa tatatcaatt agctgacgac
    16981 aattatttat tagttgttaa tgctgctaat actgaaaaag attttaattg gattttaaaa
    17041 cacaaagaga aatttgatgt tgaagtacaa aatgtatcaa accaatatgg tcaattagca
    17101 atacaaggac caaaagctag agatttaatt aatcaattag ttgatgaaga tgtaactgaa
    17161 atgaaaatgt ttgaatttaa acagggtgtc aaattatttg gagcaaacgt cattttatct
    17221 cagtcaggtt acacaggtga agatgggttt gaaatttatt gtaatatcga tgatactgaa
    17281 aaaatttggg atggtttatt agagtataat gttatgccat gtggattagg cgctcgtgat
    17341 acattaagat tagaggctgg attgccatta catggtcaag atttaactga atcaattaca
    17401 ccatatgaag gtggtatcgc ttttgcaagt aaaccattaa ttgatgctga ttttattggt
    17461 aaatctgtat taaaagatca aaaagaaaat ggtgcaccaa gaagaacagt gggattagaa
    17521 ttacttgaaa aaggaattgc aagaactggt tatgaagtta tggatttaga tggaaatatt
    17581 attggagaag taacttcagg aacacagtct ccatcatcag gaaaatcaat tgcacttgca
    17641 atgataaaaa gagatgagtt tgaaatgggt aaagagttgc ttgttcaagt tcgtaagcgt
    17701 caattaaaag cgaaaattgt taagaaaaat caaattgata aataattaaa aaggggtgtg
    17761 cattgtgagt catcgttata tacctttaac tgaaaaagac aagcaagaaa tgttacaaac
    17821 aattggtgca aaatctatag gagaattatt cggtgatgta ccaagtgaca ttttattaaa
    17881 tagagattta aatattgctg aaggcgaagc ggaaacaacg ttacttagaa gattaaatcg
    17941 cattgcaagc aagaatatca ctaaagaaac gcatacatca tttttgggtg ctggtgttta
    18001 tgatcattac gcgccatcag ttgtggatgc tatgatttca agatcagaat tttacacagc
    18061 atatacgcca tatcaaccgg aaatttctca aggtgaatta caagccattt ttgagttcca
    18121 aactttaatt tgtgaattaa cagatatgga tgtagcaaat tcttctatgt atgatgggat
    18181 gactagcttt gctgaagcat gtattttagc atttagtcaa acaaagaaaa ataaaattgt
    18241 agtctcaaaa ggtttacatt atcaagcatt acaagtactt catacttatg ctaagacacg
    18301 caaggaattc gaagtagtgg aaatcgattt agatggcact gttacagatt taaaaaaatt
    18361 agaagcagca gtggatgatg aaacagcagc tgttgcagta caatatccaa acttctacgg
    18421 ttcaattgaa gatcttgaaa agattcatag ctttattgaa gataaaaaag cattatttat
    18481 cgtatatgca aatccattag cattgggatt acttacacct ccaggttcat ttggtgcaga
    18541 tattgttgta ggtgatactc agccattcgg aattcctgct caattcggtg ggccacattg
    18601 tgggtatttt gcaacgacga aaaagttaat gcgtaaagtg ccaggtagat tagtcggtca
    18661 aacacaagat gatgaaggta atcgtggctt tgtattaaca ctacaagcac gtgaacaaca
    18721 tattcgacgc gataaagcga catctaatat ttgttctaac caagcattaa atgctctagc
    18781 gtcatcaatt gcaatgtcag cacttggtag acaaggtatc tatgatattg cagttcaaaa
    18841 tatagaacat gctaactatg ctaaacaaca atttattaaa aaaggttttg aagtattaga
    18901 tggtacatct ttcaatgagt ttgtagtcaa atttgacaaa ccaattcaac aagttaacga
    18961 ggaattagtg aagtacaata ttatcggtgg ttttgattta ggtgttgttt cagacgactt
    19021 taaaaatcat atgttaatag ctgtaactga attaagaaca aaagatgaaa tcgatacatt
    19081 tgtagaaaag gctggtgagt taaatgacta gtaaatcaag tccattaatt tttgaaagat
    19141 ctcgtgaagg cagatatgca tattcattac caaaaagtga tattaaaaca aattctgttg
    19201 agtcattgtt agatgataaa tttattcgta aaaacaaagc ggagtttcca gaagttgctg
    19261 aactagactt agtacgtcat tatactgaac tttcaaataa aaatttcggt gtagataacg
    19321 gattttatcc attgggttca tgtacgatga agtataaccc taaaattaat gaaaaggttg
    19381 ctagaatacc aggattcagt gaatcacatc cattacaaga tgaagaccaa gtacaaggtt
    19441 cattagaaat tatttatagt ttgcaagaag aattaaaaga aattactggt atggatgagg
    19501 taacattaca accagctgct ggtgcacatg gtgaatggac tgcattgatg atatttaaag
    19561 cttatcatga gaataatggt gaaggtcatc gtgatgaagt cattgtgcca gattctgcgc
    19621 atggtacgaa tccagcctca gcttcatttg caggatttaa atcagttact gtaaaatcaa
    19681 acgaacgtgg cgaagttgat attgatgact tgaaacgtgt tgtaaatgaa aatacagcag
    19741 ctattatgtt aactaatcca aacactttag gtattttcga aaaaaatatt atggaaatcc
    19801 gtgaaatcgt ccataatgct ggtggtctat tatattatga tggtgcgaat ttaaacgcta
    19861 ttatggacaa agttcgccca ggagatatgg gatttgatgc tgttcattta aacttgcata
    19921 aaacatttac tggtccacat ggtggtggcg gtcctggttc aggtccagtc ggtgtagtaa
    19981 aagaactagc aagttactta ccaaagccaa tggttattaa agatggcaac aaatttaaat
    20041 atgataatga cattaaaaat tctatcggac gtgtaaaacc attttatggt aactttggta
    20101 tttacttaag agcttatacg tatattagaa ctatgggagc aactggactt aaagaggttt
    20161 ctgaagcagc ggttcttaat gcgaattata ttaaagcacg tttatctgaa cactttgaaa
    20221 taccttataa acaatattgt aaacacgagt ttgtgttaag tggtgtgcgt caaaaagaat
    20281 ttggtgtacg tactttagac atggctaagc gattattaga tttcggtgta catccaccaa
    20341 caatctactt cccattaaat gttgaagaag gtatgatgat tgaaccgact gagacagagt
    20401 ctaaagaaac acttgattat tttatcgata cattaattag tattgctgaa gaagctaaaa
    20461 atgatcctga taaagtgtta gaagcaccac atacaactgt gattgatcga ttagacgaag
    20521 ctacagctgc tcgtaaacca atattaaaat ttgaaaatct taaacaggaa aaataaagta
    20581 ttaaacacat attccgagaa ttattattct aactttgtat gaagatttaa ggataatggt
    20641 ttcaaaatca attgaaaaag acaatttcta tttgaacaag aaaactaaac cgaagtaata
    20701 actcttaggg tttggtatta ttctttcata gaaattgtct tttcattttt tagattgcgg
    20761 taattgaatc gtattgaaaa tgagctgaac tttctttatt atgctgaaac taagtttaat
    20821 gatcagtgaa gctagagaaa tatagtaaca gactttgtta aaaaattaaa atctgagtat
    20881 tgttattgat gatcaattaa cactcagatt ttattaaatc gtatattaaa tttacaaaaa
    20941 ctatttttta gactttattt ttccagtcca ttttttatag ccgcctttta acatatagat
    21001 atctgtatat ccattctttt tcaaaatacg agcggctcta tagctagcaa tcccattggc
    21061 atcacataag tataccggtt ggtcttttct taatccttgg aatcgttgcc tgaacattgt
    21121 cataggaata ttgcgagacc cattaatgtg accgtagtca tagtcaactt tctctctaac
    21181 atcgatgact tgagcttttc taatcccatt atggaattca ttttgatcta attctttaac
    21241 agctcgcttg ttaagaattt gttgaacaat catataagca ataattgcta taattaaaat
    21301 tattgcgatg tacaaactag cactcatctt gcatcctccc taattaaacg ataatataat
    21361 tataagactg ttaggtcaaa ttatcaaaat atttcactaa agaattgcaa ttattattca
    21421 tttagttaaa ttgattaatt agcgaatcaa atattataca ttttgctgat aggagttctt
    21481 gaatatgact gaaacttgga attttattaa tacaggaagt aaagacccat attataatat
    21541 ggcaatggat gaagcgttat taaattttgt ctctagaggt gaaattgatc cagttatacg
    21601 tttttacaca tggaatcctg caacattatc aatagggtat ttccaaaggt tacaaaagga
    21661 aattgatata gataaggtta aagagaaagg ttttggtctc gtaaggcgtc aaactggtgg
    21721 ccgtggggtg ctacatgata aagagttaac ttacagtgtg attgtgcctg aatcgcatcc
    21781 gaatatgcct tctacagtta cagaagcgta cagagtgatt tcacaaggat tattagaagg
    21841 atttaaaaac ttaggatttg atacttattt tgcggtacct aaaacgcctg aagagcgtca
    21901 aaaattaaaa caacctcgaa gttcagtgtg ttttgatgca ccaagttggt atgagctagt
    21961 tgttgaaggc cgtaagattg ctgggagtgc tcaaacgaga caaaagggcg taatcctcca
    22021 acacggttcg attttacaag atattgatat tgatgaactg tttgatatgt ttatttataa
    22081 aaatgaaaga ttaaaattaa aaatgaaaga ggcattcgtt gaaaaagcag ttgccatcaa
    22141 tgatatttca gataaacaca ttactattag tcaaatggaa gaagctttcg agaaaggttt
    22201 taagaaaggt ttaaatatag aattaaagcc acttgaatta acagaagctc aattggcaga
    22261 agtggaagaa ttaactgaaa aatatcgttc agatgaatgg atgtttagaa agtagttttt
    22321 agaatgaaaa atggaagcac gtagactatt ttacctacaa gtgcttccat ttttttatct
    22381 attttcttct ttgatttctt ttatacttac gcattgcttt acggtattta cgttgatctt
    22441 cagttaaaat gaagaaataa tatataagat aaataatacc agctattaca gcaaagctga
    22501 ctaacattct gacgattgaa aaaataaagg catctagatt cattactaat ccaatcgcag
    22561 caataataag tacaagataa aatattatat tacgcattaa cagactccta tcatgatttt
    22621 gcatttaagt ttaattttga caacgcttgt tgtccttttg taagttgttt tttatcttta
    22681 ttttgatagc catttttaat atcatcaaat gcatgattca aatcagagtt taatttatcg
    22741 atatttttag acgttttttt atcatcatca ctaagtgata aaccatcgat agcatctttg
    22801 tatgaagtgt gagcactttg aatatcatta gaaatttgat ttaatttcga ttgaacattc
    22861 ttatcgcctt tgtttttact tacatctttc tcaatatcgt tataggattt caaagcttta
    22921 gcaactttgt cgtagtatgt tgatgtaaca ttcatcaatt taattttcgt attattagat
    22981 gcagtttttt tactgttttc tttatccttt tcaagccctt taattttaga tttagaatca
    23041 ctaatttgtt gattaagttc ttgaatatct agtttgagtt gatgattatc ttctcttaaa
    23101 tctgttgttt tttcttctaa tggtgctaaa ttttgtgatc cacatccagc taacaataat
    23161 gttgcgccaa caattgaaac caattttttc attactatct ccctaaaatc aatatctatt
    23221 attttttatc cttattatga tattatttta atgtataaag ttgaaatgca caaacgtttc
    23281 actaggaggt cataagatga gcagaataac acaagtacat cgtattttag aacaaaaaca
    23341 tttagatgca ataatcatac tttcagatta caatagaaga tatttgtcag gatttactgg
    23401 gactagcggt gcgctaatca tatctaaaga taaacaatat ttgataacag actttagata
    23461 tattgatcaa gcaactaagc aggcgccaaa ttatgaaatt attaatcgta aatctactat
    23521 tattggtgag attaaagaat tgctacacca agaaaatttt gaaaatgtag gttttgaggg
    23581 gcaccatgta agttatgata cataccttga attaaataaa agccgtatat cattaataag
    23641 catttctaat actgtagata aaattagaga cgtcaaagat gctgacgaaa ttgctttaat
    23701 tcaaaaagca gctaatattg ttgatgaaac atatgaatat attttaactg ttgtaaaagc
    23761 aggtatgact gaaaaagaat taaaggcaat attagaaagt aaaatgctag aattaggagc
    23821 agatggacca tcattcgata cgattgtagc atctggtcat agaggtgcat taccacatgg
    23881 tgttgcaagt gataaaatta ttgaaaaagg cgacatgatt acattagatt ttggcgcgta
    23941 ttataacggc tattgttcag atattactag aacatttgct attggagaac cagatcctaa
    24001 actgaaagaa atatatcaaa tagtacttga atctcaaatg aaagcaatta atgagattag
    24061 acctggcatg actggtgcag aagctgatgc catttcaaga aactatttag agtcaaaagg
    24121 gtatggaaaa gaatttggac attcactagg acatggtatt ggtttagaaa tccatgaagg
    24181 gccaatgctg gctcgtacga tacaagataa acttcaagtt aacaactgtg ttacagtaga
    24241 acctggtgtt tatatagaag gtttgggcgg tataagaata gaagatgata ttttaattac
    24301 agaaaatggt tgtcaagtct ttactaaatg cacaaaagac cttatagttt taacataagc
    24361 gtgtaaaatg aggaggaaac tgaatgattt cggttaatga ttttaaaaca ggtttaacaa
    24421 tttctgttga taacgctatt tggaaagtta tagacttcca acatgtaaag cctggtaaag
    24481 gttcagcatt cgttcgttca aaattacgta atttaagaac tggtgcaatt caagagaaaa
    24541 cgtttagagc tggtgaaaaa gttgaaccag caatgattga aaatcgtcgc atgcaatatt
    24601 tatatgctga cggagataat catgtattta tggataatga aagctttgaa caaacagaac
    24661 tttcaagtga ttacttaaaa gaagaattga attacttaaa agaaggtatg gaagtacaaa
    24721 ttcaaacata cgaaggtgaa actatcggtg ttgaattacc taaaactgtt gaattaacag
    24781 taactgaaac agaacctggt attaaaggtg atactgcaac tggtgctact aaatcggcaa
    24841 ctgttgaaac aggttataca ttaaatgtac ctttatttgt aaacgaaggt gacgttttaa
    24901 ttatcaacac tggtgatgga agctacattt caagaggata atctctaatt tgttaacaaa
    24961 tagcttgtat acactatact gatttaacgt aagatattcc aaataagtct cataaagcta
    25021 ttgcctaaaa tgattatagg ttatatgctg atatgaggct ttttattttt aaaataattt
    25081 ttaaaatata aaacgaatcg tctaattggt agtgaaaaaa catagacatg agtaaaggta
    25141 tatatctaca tatcatattg ttgaggatta aacataatag ctaataaaaa taacattgat
    25201 atgtttaact gaatgcataa aatttttaat caagagttaa gatgagtcaa tgttaagtaa
    25261 taaatacaca agtgttttta atttaaaatg tgtttttatt ataactttgg gatagactta
    25321 taatgtcgcc agcaatatga acatgcttga attgaagagt tgtctcaagt aaaatagacg
    25381 ggtagatgaa aacaaactga aggagtcagt aataatgaac tttaaagaaa tcaaagaatt
    25441 aattgaaatt ctggataaat caactttaac ggaaatcaat attgaagata ctaaaggcaa
    25501 agtgacgctt aagaaagaaa aagaaactga gattatcacg ccacaaattt cacaaatgcc
    25561 agttgaagct gcggcaatgc ctatgcctca agtacaatca actgatagca ataaaactga
    25621 agctccaaag ccaacttcag ataatcacaa aacaattaat gcacctatgg taggtacatt
    25681 ttacaaatcg ccttctccag acgaagaagc atatgtgcaa gttgggtaca ctgtttcaaa
    25741 tgaaacaaca gtgtgtattt tagaggcaat gaaactattt aatgaaattc aagcagaaat
    25801 ttcaggtgaa attgttgaaa tcttagtaga agacggacaa atggtagagt atggccaacc
    25861 gttatttaag gtgaaataat gaaaaaggtt ttaattgcaa accgcggtga aatcgcagtt
    25921 aggattattc gcgcttgtcg tgatttaggc atccaaactg ttgcaatcta ttctgaaggg
    25981 gataaagatg cgctacatac tcaaattgct gatgaagcat attgcgtagg tcccactttg
    26041 tctaaagatt catatttaaa tattccgaac atcttatcta ttgcaacttc tacaggttgt
    26101 gatggcgttc atccgggtta tggcttttta gctgaaaatg ctgactttgc agaattatgc
    26161 gaagcatgcc aattgaagtt cattggacca agttatcaat ctatccaaaa aatgggtatc
    26221 aaagatgttg ctaaggcaga aatgatcaaa gccaatgttc cagttgttcc tggtagtgac
    26281 ggtttaatga aagacgtctc agaagctaag aaaatcgccc aaaaaattgg ctatccggtc
    26341 atcattaaag ctactgctgg cggtggcgga aaaggtatcc gtgttgctcg tgatgaaaaa
    26401 gaacttgaaa ctggcttccg aatgacagaa caagaagctc aaactgcatt tggtaatggt
    26461 ggactttata tggagaaatt catcgaaaac ttccgccata ttgaaatcca aattgttggg
    26521 gacagctatg gtaatgtaat tcatttagga gaacgtgatt gtacaattca aagacgtatg
    26581 cagaaattag tggaagaagc accttcccca attttagatg atgaaacacg tcgtgaaatg
    26641 ggaaatgccg cagtgcgtgc agcgaaagct gtaaattatg aaaatgcggg aacaattgag
    26701 tttatatatg atttaaatga taataaattt tattttatgg aaatgaatac acgtattcaa
    26761 gtagaacatc ctgtaactga aatggtaaca ggaattgatt tagttaaatt acaattacaa
    26821 gttgctatgg gtgaagtgtt accatataaa caagaagata ttaaattaac aggacacgca
    26881 attgaattta gaattaatgc tgaaaatcct tacaagaact ttatgccatc accaggtaaa
    26941 attgagcaat atcttgcacc aggtggatat ggtgttcgaa tagagtcagc atgttatact
    27001 aattatacga taccgccata ttatgattcg atggtagcga aattaatcat acatgaaccg
    27061 acacgagatg aagcgattat ggctggcatt cgtgcattaa gtgaatttgt ggttcttggt
    27121 attgatacaa ctattccatt ccatattaaa ttattgaata acgatatatt tagaagcggt
    27181 aaatttaata caaacttttt agagcaaaat agcattatga atgatgaagg ttaataggag
    27241 gtcaatccat ggtcaaagta actgattatt caaattcaaa attaggtaaa gtagaaatag
    27301 cgccagaagt gctatctgtt attgcaagta tagctacttc ggaagtcgaa ggcatcactg
    27361 gccattttgc tgaattaaaa gaaacaaatt tagaaaaagt tagtcgtaaa aatttaagcc
    27421 gtgatttaaa aatcgagagt aaagaagatg gcatatatat agatgtatat tgtgcattaa
    27481 aacatggtgt taatatttca aaaactgcaa acaaaattca aacgtcaatt tttaattcaa
    27541 tttctaatat gacagcgata gaacctaagc aaattaatat tcacattaca caaatcgtta
    27601 ttgaaaagta atgtcatacc taattcagta attaaataaa gaaaaataca aacgtttgaa
    27661 ggagttaaaa atgagtcgta aagaatcccg agtgcaagct tttcaaactt tatttcaatt
    27721 agaaatgaag gacagtgatt taacgataaa tgaagcgata agctttatta aagacgataa
    27781 tccagattta gacttcgaat ttattcattg gctagtttct ggcgttaaag atcacgaacc
    27841 tgtattagac gagacaatta gtccttattt aaaagattgg actattgcac gtttattaaa
    27901 aacggatcgt attattttaa gaatggcaac atatgaaata ttacacagtg atacacctgc
    27961 taaagttgta atgaatgaag cagttgaatt aacaaaacaa ttcagtgatg atgatcatta
    28021 taaatttata aatggtgtat tgagtaatat aaaaaaataa aattgagtga tgttatatgt
    28081 cagattattt aagtgtttca gctttaacga aatatattaa atataaattt gatcaagatc
    28141 cacatctcca atctgtattg attaaaggtg agctttcaaa tttcaaaaag cattcaagtg
    28201 gtcatttata ctttaatgtg aaagataaag aaagcgttat aagtgccatg atgttcaaag
    28261 gtagtgcttc taaattaaac ttcgaaccta aagaaggaga tgaagtctta ttagaagcac
    28321 gtgtttctgt ttttgaacgt cgtggaaact atcaaattta tgtaaataaa atgcaattag
    28381 atggtatagg gaacttatat caaaaattag aagcattaaa gaaaaaatta actgaagaag
    28441 gttgttttga taaagcgaat aagaaatcaa tacctaagtt tccaaaaaaa attgcagttt
    28501 taacagcgag tacaggtgcc gcaattcgag atatccattc aacgataaat agtcgtttcc
    28561 cattagctga acaaatacaa attagtactt tggttcaagg tgaaaaagca aaggacgaca
    28621 ttattgaaaa aattgaatat gcagatagtt taggtgtaga taccattatt gtaggtcgag
    28681 gcggtggatc catagaagat ttatggaatt ttaacgaaga agctgtcgtc cgtgcaatat
    28741 ataattgtaa gacaccgatt atatcagcag taggtcatga aacagacttt acattaagtg
    28801 attttgctgc agacatcaga gctgcgactc caactcaagc tgctgttatt gcaacaccag
    28861 accaatatga attgctgcaa caaatacagc aatatcagtt tacattgact cgtttcatca
    28921 agaaacattt agaacaacaa cgtaaacatg ttgaacattt gtcatcgtat tacaagttta
    28981 aacaaccaac tttattgtat gatcaacaga tacaacgtcg agatgattta gaaaagagac
    29041 tgaaacaaca aattcaggca acttttgaac aacagagaca tcgattaatg ctgttgcaac
    29101 aacgctataa tttaaaagcg ttactaagta gtgttaatca agaacaacaa aataatcttc
    29161 aattgacaaa ccaacttgtt aaattattga attctaagat attaagttat aaaaatgatt
    29221 tgaaaaataa agtagaaaac ttaaacaatt taagtccaac taatacaatg ttgcgtggat
    29281 atgcaattgt taataaaaaa gacgaagtca ttacgagtac taaagattta acagaaaatg
    29341 atcaattgac gttaacaatg aaagatggct tagtagatgc aaaagttacg aaagtaaggt
    29401 gtaataatga ctaaagaaac gcaaagtttt gaagaaatga tgcaagaatt agagcaaatt
    29461 gttcaaaaat tagataatga aacagtatct ttagaggaat cattagattt ataccaacgt
    29521 ggtatgaaac tatcagcagc ttgtgacaca actttaaaaa atgccgaaaa aaaggtgaat
    29581 gacttaataa aagaagaagc tgaggatgta aaaaatgacg aatctaccga tgaataaatt
    29641 aatagatgaa gtcaataatg aattatcggt tgcgataaat aaatcagtaa tggatactca
    29701 gctagaagaa agtatgttgt attcattaaa tgctggaggt aaacgcatcc gaccagttct
    29761 gttattactc actttagatt cactaaatac cgagtatgag ttaggtatga agagcgcaat
    29821 tgcactagaa atgattcata catattcact tattcatgat gacctaccag cgatggataa
    29881 tgatgattat cgacgaggga aattaacaaa tcataaagta tatggtgagt ggactgcgat
    29941 attagcaggt gatgctttat taactaaagc atttgaactt atttcaagtg atgatagatt
    30001 aactgatgaa gtaaaaataa aagttctaca acggctgtca atagcaagtg gtcatgttgg
    30061 aatggtcggt ggacaaatgt tagatatgca aagcgaaggc caaccaattg atcttgaaac
    30121 tttggaaatg atacacaaaa caaaaacagg tgcactatta acttttgcgg ttatgagtgc
    30181 agcagatatc gctaatgtcg atgatgcaac taaagaacat ttagaaagtt atagttatca
    30241 tttaggtatg atgtttcaga ttaaagatga tttattagac tgctatggtg atgaagcgaa
    30301 gttaggtaaa aaagtgggca gcgatcttga aaataataaa agtacgtacg tgagtttatt
    30361 aggaaaagat ggcgcagaag ataaattgac ttatcataga gacgcagcag tgtatgaact
    30421 aacgcaaatt gatgaacaat tcaatacaaa acacttatta gaaatcgttg atttatttta
    30481 tagcagggat cactaaaagc aaatatatcg attagcaaca attgtaaagt ttgaaatgtc
    30541 tcaaaaggca tattcaactg acgttgtttg ttaatcgatt tttctcatgt tgaaacttaa
    30601 aattatgttg aagtctttca tttaaaaata gaattttcaa tttctatacg acaatattcg
    30661 catctgtgat atcaatgtga ttttaattaa atatgttcaa acaattgacg cttattaaat
    30721 ctaataatta gcaagtttat tacacatata ttcattttta tacatatttt aagcaattgt
    30781 tatgcgtaat atgaaaaata tttataaata gataaccaag atagataaac catgtttacc
    30841 ctttttacgt aaaggtgttt agtagtcgta aatcagtgca tgtgttaaaa taaatgtata
    30901 aatattcgta atcagaggtg tttactgtgc ccaaaaaatc ggttaggcat ataaaaatta
    30961 gagaaattat ttcaaatgaa cagatagaga cacaagatga attagttaaa cgattaaacg
    31021 attatgattt aaatgtcact caagcaactg tttctcgtga tattaaagaa ctacaactta
    31081 ttaaagtacc tataccttca ggtcaatatg tttatagttt accaaatgat agaaaattcc
    31141 atcctttaga aaaattggga cgttatttaa tggattcctt tgttaatata gatggtactg
    31201 ataatttact tgttctaaaa acattacctg gtaatgcaca atctattgga gctatattag
    31261 accaaatcaa ttgggaagaa gtactaggca caatttgtgg tgatgatact tgtttaatta
    31321 tttgtcgaag caaagaggca agtgatgaaa tcaagtcaag aattttcaat ttgttataag
    31381 gatgcgatga gtttatgtta caaaccttat caatcaagca atttgctatt attgaagagt
    31441 tagaaattca attttctgat ggtttaactg ttttaagtgg tgaaacgggt tcaggtaagt
    31501 caattattat agatgcaatt ggacaattaa ttggaatgag agcttcatct gattttgtaa
    31561 gacatggtga aaaaaaggct gtcatcgaag gtatatttga tattgacgag agtaaagatg
    31621 ctatacatat attgaaaaat atggatattg atgtagatga agatttttta ttagttaaac
    31681 gggaaatttt tagctctggt aaaagtcttt gtaaaattaa taatcaaaca gttactttac
    31741 aagatttacg aaaagttatg caagaattat tagatattca tggccaacat gaaacgcagt
    31801 ctttgttgaa acaaaaatac catttaacat tattggataa ttacgcagaa tcacgttatc
    31861 aagatttgtt ggataaatat caccaaactt ttcaaaatta taaagccaaa aagcaagagt
    31921 tagaagattt agaatcagca gaccaagcat tgctgcagcg tttagattta atgaaatttc
    31981 aattagaaga attgtctgaa gcacacctaa aagaaggtga aatagagcaa cttgaaattg
    32041 atattaaacg cattcaaaac tctgaaaaat taagcttagc acttaataac gcacatatga
    32101 cattaacgga tgaaaatgct atcactgatc gtttgtatga actaagcaac catttgttaa
    32161 caataaacga tatagttcca aacaaatatg acaaattaaa agaagatatt gatcaatttt
    32221 attacatttt agaagatgca aaacatgagt tatatgatga aatggctaat acagaattcg
    32281 acgaacaagt gttaaacgag tatgaatctc gtatgaattt gctgaataat ttaaaacgca
    32341 aatatggaaa agatatttca gaattaatct catatcaaga aaaacttaat aatgaaatca
    32401 ataaaattga aaactatgaa caaagtacat cgcagttacg agaagaaata aatgcattgt
    32461 ataatcaagt tatagaggtt ggacaagcgc tatcaaagca gcgtcgtata gtcgctaggg
    32521 agttaagaga ccacattgta tcggaaattc aaaacttaca aatgaaagat gcaaatcttg
    32581 agatttcatt taaaaaatta gaagaaccga atattgatgg aatcgaattt gtagaatttt
    32641 taatcagtcc taataaaggg gaaccattaa aaagtttaaa taaaattgcg tcaggtggag
    32701 aactttctag aattatgtta gcgttaaaaa gtatttttgt taaatcgaga ggtcaaactg
    32761 caattttatt cgatgaggtt gactcaggtg tatctggaca agctgcacaa aaaatggcag
    32821 agaaaatgcg agatatagca gaatatatac aagttatttg tatttctcac ttgccacaag
    32881 ttgcatcgat gagcgaccat catttattaa tttcgaaatc atcaaaagat gatcgtacaa
    32941 caacacaagt tcaagagtta attggcgatg ataaagtaga tgaaattgca cgaatgattt
    33001 caggtgcaag tgttactgat ttaactcgag aaaatgcaag agaaatgata caacacaatc
    33061 aaagacgtag ataatttcca aagtgtgttg aatactcatt tgtggactta tttatgtgca
    33121 ttcaaactaa atagacaatc atgtaaaata ggtaattaat ggacatgaaa actatgtatt
    33181 aataaatttt caatggatat atatcattag ttaggagtaa gaacatgtca gagaaacaat
    33241 atgatttagt cgttctcggt ggaggtactg caggatatgt tgctgcgata cgtgcgtctc
    33301 aattaggtaa gaaagtggca atagtagaac gacaactatt aggaggtact tgtctccata
    33361 aaggttgtat tcctactaaa tcactgctta agtcagcaga agtatttcaa acagtaaaac
    33421 aggcagcaat gtttggcgtt gatgtcaaag atgctaatgt taattttgaa aatatgttgg
    33481 cacgaaaaga agacattatt aatcaaatgt atcaaggtgt aaagcattta atgcaacaca
    33541 atcacattga catttataat ggcacgggac gtattctagg tacatctata ttttcacctc
    33601 aaagtggcac aatttctgtc gaatatgaag atggtgaatc agacttatta cccaaccaat
    33661 ttgtattaat tgcaactggt tcttcgcctg cagagttgcc atttttatca tttgatcatg
    33721 ataaaatttt atctagcgat gatatattat cattaaagac gttaccatca agtattggta
    33781 ttattggtgg tggtgttatc ggaatggaat ttgcatcatt gatgatagat ttaggtgttg
    33841 acgtaacagt tatagaagca ggtgaaagaa ttttaccaac tgaaagtaaa caagcttcac
    33901 aactattaaa aaaatcatta tcagcacgtg gtgttaaatt ctatgaggga ataaaacttt
    33961 ctgaaaatga tataaatgtt aacgaagatg gtgttacatt tgaaatttcc tcagacataa
    34021 ttaaagtaga taaagtattg ctatcgattg gtagaaaacc taacacatca gatattggtt
    34081 taaacaacac taaaataaaa ctttcaacat caggacatat tttaacgaac gaatttcaac
    34141 aaactgaaga taaacatatt tatgcagctg gtgattgtat tggaaaatta caattggcac
    34201 atgttggatc aaaagaaggt gttgtggccg tcgatcatat gtttgaaggg aacccaatcc
    34261 cagtaaacta taacatgatg cctaagtgta tttattcaca acctgaaatt gcttctatcg
    34321 gtttaaacat tgagcaagca aaggcagagg gaatgaaagt taaaagtttt aaagtaccat
    34381 ttaaagcaat tggtaaagca gtgattgata gccatgatgc aaacgaaggg tatagcgaaa
    34441 tggtgattga tcaatcaact gaagaaattg tgggtattaa tatgattggt ccacatgtaa
    34501 cagaattgat taatgaggca tcactgttac agttcatgaa tggctcggca ttagaattag
    34561 gactaacaac acacgcacat ccttccatct ctgaagtgtt gatggaatta ggattgaaag
    34621 cagaaagtag agctattcac gtataaatag gaggatttaa catgattgat tataaatcat
    34681 taggccttag cgaagaagac ctaaaagtaa tatataaatg gatggattta ggtagaaaaa
    34741 tagatgaaag actgtggtta ttgaaccgtg caggtaaaat tccatttgtt gtaagtggtc
    34801 aaggacaaga agcaactcag attgggatgg catacgcatt agaagaaggt gatattactg
    34861 cgccttatta tagagatcta gctttcgtta cttatatggg tatatcagcg tatgatacgt
    34921 ttttatcagc gtttggaaag aaagacgatg ttaactctgg tggaaaacaa atgccatcac
    34981 actttagtag tagagctaag aatattttgt cacaaagttc accggtagca actcaaatac
    35041 cccatgctgt tggtgctgct ttagctataa aaatggatgg taagaagaaa attgcaacag
    35101 caactgttgg tgaaggtagc tcaaaccaag gtgacttcca tgaaggttta aacttcgcgg
    35161 gtgtacacaa acttcctttt gtatgtgtca ttataaataa taaatatgca atttcagtac
    35221 ctgattcatt acaatacgca gctgaaaaat tatcggatag agcacttggt tacggtatac
    35281 atggtgaaca agtagatggt aatgatccat tagcaatgta taaagcgatg aaagaagcaa
    35341 gagatcgagc tatttctggt caaggttcaa ctttgattga agcagtaaca agtcgtatga
    35401 cagctcattc atcagatgat gacgaccaat atcgtacgaa agaagagcgt gaagcgctta
    35461 aaaaagcaga ctgcaatgaa aagttcaaaa aagagttgct ttcagctggc attatcgatg
    35521 atgcttggtt ggcagaaata gaagcggagc ataaagacat catcaataaa gcgacaaagg
    35581 ctgctgaaga cgcgccatat ccaagtgtcg aagaagccta tgcatttgtg tacgaagaag
    35641 ggagtcttaa ctaatggcta aattatctta tttagaggcg atacgccagg cacaagactt
    35701 agcattacaa caaaataaag atgtgtttat tcttggtgaa gatgttggta gaaaaggtgg
    35761 cgtatttggt actactcaag gactgcaaca aaaatatggt gaagacagag ttatcgatac
    35821 gccattagct gagtcaaata ttgttggaac tgccattggt gcagctatgg taggtaaaag
    35881 accaattgca gaaattcaat ttgcagattt tattttacct gcgacaaatc aaattattag
    35941 tgaagctgcg aaaatgcgtt atcgttcaaa taatgattgg caatgcccat taacgattcg
    36001 tgcaccattt ggtggcggtg ttcacggagg actatatcat tcacaaagta ttgaaagtat
    36061 atttgcttca tcaccaggtt taacaattgt tattccttcc acaccgtatg atgctaaagg
    36121 tctattatta tcttcaattg aatcaaatga tcctgtttta tactttgagc ataaaaaagc
    36181 ttatcgtttc ttaaaggaag aagtgccaga agaatattac actgtacctt taggaaaagc
    36241 agatgttaaa cgtgaaggtg aagatttaac agtattttgt tatggattaa tggtcaatta
    36301 ttgcttacaa gccgctgata ttttagctgc agacggtatc aatgttgaag tcgtagattt
    36361 acgaactgtt tatccattag ataaagaaac aattattgat cgtgctaaac atacaggtaa
    36421 agttttactt gtaactgaag ataatttaga aggtagcatt atgtcagaag tgtcagcgat
    36481 tattgcagag cattgcttgt tcgatttaga tgcaccaatc atgcgtttag ctgctccaga
    36541 tgtaccatct atgccatttt ctcctgtatt agaaaatgaa attatgatga atccagaaaa
    36601 aatcttaaat aaaatgcgtg aattagcaga attctaggga gggaaagtca tggaaataac
    36661 aatgcctaag ttaggtgaga gtgttcatga aggcaccatt gaacaatggt tagtttctgt
    36721 tggtgatcat attgatgaat atgaaccatt atgtgaagtt attacagata aagtgacagc
    36781 tgaagtccct tccacgatat caggaacaat tacagaaatt ttagttgaag cggggcagac
    36841 agtagctatt gatacaatta tctgtaaaat tgaaactgct gatgaaaaga caaatgaaac
    36901 aactgaagag atacaagcaa atgtggatga gcatactcag aaatctacta aaaaagctag
    36961 tgcaacagtg gaacagacat ctactgctaa acaaaatcaa ccacgtaata atggtcgctt
    37021 ttcacctgtt gtatttaaac tcgcttcaga gcatgacatt gatttatcac aagttgtagg
    37081 tagtggattt gaaggtcgtg taactaagaa ggatataatg tcagttattg aaaatggtgg
    37141 taccacagct caatctgaca aacaagttca aacacaatca acatcagtag atacatcaag
    37201 taaccaatca tctgaagaca atagtgaaaa cagcacaata ccagtaaatg gtgtgcgtaa
    37261 agcaattgcg caaaatatgg ttaatagtgt aacagagatt ccacatgcat ggatgatgat
    37321 tgaagtagat gctacaaatc ttgtgaatac gagaaatcat tataaaaaca gctttaaaaa
    37381 taaagaagga tataatctaa cgttttttgc tttctttgta aaagctgtag cagatgcttt
    37441 aaaagcatat cctttattaa atagtagctg gcaaggaaat gaaattgtct tacataaaga
    37501 cattaatatt tcaattgctg ttgctgatga aaataaatta tacgtacctg tgattaagca
    37561 tgcagacgaa aagtcaatca aaggtatagc tagagaaatt aatactttag caacaaaagc
    37621 gcgtaataag caattgacag ctgaagatat gcagggcggt acatttacgg taaataatac
    37681 tggtacgttt ggttctgtat catcaatggg tattataaat caccctcaag cagcgatttt
    37741 acaagtagaa tcaatcgtta aaaagccagt agtaattaat gatatgattg caattcgtaa
    37801 catggttaat ttatgtattt caattgatca tcgtatttta gatggtttac aaacaggtaa
    37861 atttatgaat catattaaac agcgtatcga acagtatact ttagaaaata caaatatata
    37921 ttagtgataa catagatgca tctatcgaca acttgtttta tcttgttctt gtcgatggat
    37981 gtattttttt gggcaataaa atatgtgcaa tatattcaaa aaaagataaa gaacaataat
    38041 caacatggtt gaatgaattt ttgcagtaaa gtcaaaataa gacatcatac ttgaaacata
    38101 ttaatgaaaa caggtgaaca aattagtttc catgatttta agcacaataa tgtttggtat
    38161 attgttaaaa ttgtgtctaa atataggtgt gattcagatt agtttattga acaatatgtt
    38221 attaattagt agaatgagga tagtttaaat ataaagggat aggtgattga acttatggac
    38281 atgaatttcg atttatacat gaacggtgtt gtagaacaag caaggaatga aattgaatct
    38341 gcgggatatg agcaattaac tactgcagaa gatgttgaca aagttcttaa acaagatggt
    38401 acaacactag ttatgatcaa ttctgtatgt ggatgtgcag gtggtatcgc aagaccagca
    38461 gcatcacatg ctttacatta tgacgtatta cctgatcgtc tagtgacagt atttgctgga
    38521 caagataaag aagcgacaca aagagcgcgt gaatacttcg aaggttatgc gccttcaagt
    38581 ccgtcatttg cattagtaaa agatggaaag attacagaaa tgattgaaag acatcaaatc
    38641 gaaggtcatg atgtgatgaa cgtaattaat caattacaaa cattattcaa taaatattgt
    38701 gaagaaagat aagaggcgct aacccatgtt aaagttaaat ccttacaaga ttggatttag
    38761 aacaataaaa acagcagtgg gtatgacttt aggtgtaatt attagtaagc tgttaggttt
    38821 agataattat gcttcaagcg ccatattagt cgtattatgt attaaacata caaaagtaca
    38881 ttcgctacaa gcgattattt caagattagt atcatgtttt ttagtattgt ttttaggttc
    38941 agcaatattt agtttattag gccagagtcc aattgtactc ggtattatcg tattgttatt
    39001 tataccatta actgtcgtat taaaagtaca agaaggtgtc attacgagtt gcgttatatt
    39061 acttcatgtt tttaatgcaa aatcaattga tgtacattta attgttaatg aaacattatt
    39121 actgttaatt ggactaagca ttgcatttac aatgaattta atgatgccaa gtttagacaa
    39181 acaactagac gaatacaaat gtaaaattga gcaacaaatt gctgatattt ttagtaaata
    39241 tagttatatt tgtgaaaaat atgaagatac cattgcgatt gaatttgaag cgttactttt
    39301 aaatattaaa aaggcgaagt ctatcgcgtt ccgagatgtt aaaaatcatt ttgttagaaa
    39361 cgaaaattca tactatcatt attttgatat gcgagaagag caagtggaat tgttaatgag
    39421 aatgaaaccg ctcatcgaaa gtatctgtca taaagatcca cttttaaatg atgttgcgtc
    39481 actgctgaaa gaaattggtc taaatgtgaa tagtaatgac tatacagcaa tgcgtttaca
    39541 caatttgtat gagacgcgtt tgaaattgga tgaactgcca ttgccaacaa cgcacaaagc
    39601 gcttaactcg agagcaagta ttattcaaat attaaatgaa ttagaagaat atttacaaat
    39661 caaatcgcaa tttggttcat tgaaaatgca tagtgaagta gcttaaaaaa taatccatcc
    39721 gtatgaccca tgtatgaaag taatcgttgc aatacgataa cttattaata catgcgttta
    39781 taacggatgg atttttaatt gtatgatttt gtataggtag ttgagatata gtttataaaa
    39841 ttggaatgat actcgttaat aacaatgcta atacaactga tacaagcata acgataatga
    39901 taattcttaa aactttattt tgcattttgt gtgcctccaa atgaataacc tttgtattaa
    39961 taattacgac ataagatata aaacttttaa cttgagacga tataactagc aatcatcata
    40021 aaggaatata ataaaaaaca tgagtaagtt tgcttatgtc attttcctca ttatacgata
    40081 tcattgaaaa atcaatcaat atatttttga caaagcttag tttgagttac aataaatata
    40141 tatattaaat tgaaaataat atgacacaat ttacaagcct gataaatctg tgtaacgtca
    40201 attactgtaa cattttattt catcaatttt taccgtttgg cgtacttgaa aattttgata
    40261 aaaggggttc cattatgatt aatgagcaaa gattacttaa tacgttttta gaacttgtac
    40321 aaatcgattc tgagacaggg aatgaatcaa caatccaacc tattttaaaa gaaaaattca
    40381 tagcattagg gttagatgtt aaagaagatg aagcggctaa acatcctaaa ttaggtgcca
    40441 ataatctagt gtgtacaatg aatagtacta tcgaagaagg cgaagtacct aaattatatt
    40501 tgacgagcca tatggatact gttgtacccg caattaatgt aaaggcaatt gtaaaagacg
    40561 acggctacat atactctgat ggtacgacta ttctaggtgc agatgataaa gcaggattag
    40621 cagcgatgct tgaagttttg caagtgatta aggaacaaca aatcccacat ggacaaattc
    40681 aatttgtgat tactgttgga gaagaatcag gtttaattgg tgctaaagaa ttaaattcag
    40741 agttgttgga cgcggacttt ggttatgcta ttgatgcaag tgctgatgtc ggcactacgg
    40801 ttgtaggtgc accgacgcaa atgttaattt cagctaaaat tattggcaaa acagctcatg
    40861 caagtacgcc aaaagagggt gttagtgcta ttaatattgc ggcgaaagca attagtcgaa
    40921 tgaaattagg acaagttgat gaaataacta ctgccaatat tggtaagttt catggcggtt
    40981 cagctacgaa tattgttgca gatgaagtca ttttagaagc agaggcacgt tctcacgatc
    41041 cagaaagaat aaaaacacaa gtcaaacata tgactgatgt gtttgaaact actgcatcag
    41101 aattaggtgg gaaagcagaa gttacagtgg agcaaagtta tccaggattt aaaattaatg
    41161 ataatgaagc ggttgttaaa attgcacaag aaagtgctcg taatttagga ttatctgcaa
    41221 atacaattat ttctggtggc ggttcagacg gcagtattat taatacattt ggtattcctt
    41281 cagtcatttt aggagtgggt tatgaaaaaa tccatacaac aaatgagaga atgccgatta
    41341 aatcattgaa cttgcttgca agtcaagtgt tagaaataat caaaatagtt gcgcgacaat
    41401 cgaaatgatt tagtgtagtg tatgtctatt ttgtgataca atactaatga aaaatcaaca
    41461 agtgaggtaa gtaatatgac acaacaaatt ggagttattg gtttagccgt tatgggtaaa
    41521 aacctagctt ggaatattga atcacgcgga tatagtgtat ctgtatttaa ccgctcaagt
    41581 gaaaaaactg atttaatggt tgaagaatca aaagggaaaa atattcatcc aacgtattca
    41641 ttggaagaat ttgttaattc tttagaaaaa ccacgtaaaa ttttattaat ggttcaagca
    41701 ggtaaagcta cggatgcaac gattgatagt ttgttacctt tattagatga tggagatatt
    41761 ttaattgatg gtggtaatac aaactatcaa gatactatca gacgtaataa agcattagca
    41821 caaagtgcaa tcaactttat tggtatgggc gtttctggtg gtgaaattgg agcgttaact
    41881 ggtccgtcat taatgccggg tggacaagaa gaagcttata acaaagttgc agatattctt
    41941 gatgcaattg ctgctaaggc aaaagacggt gcttcatgtg ttacttatat tggtccaaat
    42001 ggtgctggac actatgtgaa aatggtacac aatggtatcg aatatgctga catgcaatta
    42061 attgcagaaa gttatgctat gatgaaagaa ttattaggca tgtctcatga agacattgct
    42121 caaacgttca aagactggaa tgctggtgaa ttagaaagtt atttaattga aatcactggt
    42181 gatattttca tgaaattaga tgaaaataaa gaagcattag ttgaaaaaat tcttgatact
    42241 gcaggtcaaa aaggtacagg aaaatggact tcaattaacg cattagaatt aggtattcca
    42301 ttaacaatca ttactgaatc tgtatttgca cgttttatct cttcaatcaa agaagagcgc
    42361 gtaaatgctt ctaaagaatt aaatggtcca aaagcatcat ttgatggtga caagaaagac
    42421 tttttagaaa aaattcgtaa agcattatat atgagtaaaa tttgttctta tgcacaaggt
    42481 ttcgcgcaaa tgcgtaaagc aagtgaagat aatgaatgga atttaaaact tggtgattta
    42541 gctatgattt ggagagaagg ttgcattatc cgtgcacaat tcttacaaaa gatcaaagat
    42601 gcttacgata ataatccagg attacaaaac ttattgctag atccttactt taaaaacatc
    42661 gttactgaat atcaagatgc gctacgtgat gttgtcgcaa ctggtgttca aaatggtgta
    42721 ccaacacctg gtttctcttc aagtattaat tactatgata gttaccgtgc agctgattta
    42781 cctgcaaact taattcaagc acaacgtgac tacttcggtg ctcacacgta cgaaagaaaa
    42841 gataaagaag gcgtattcca tacacaatgg attgaagaat aatattgatt aaag
//
LOCUS       DAPSKH010000015        42141 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPSKH010000015 DAPSKH010000000
VERSION     DAPSKH010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 42141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42141
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.015"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(203..1458)
                     /locus_tag="RPH49_000926"
                     /pseudo
     CDS             complement(203..1458)
                     /locus_tag="RPH49_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001569336.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3578 domain-containing protein"
     gene            complement(1780..2259)
                     /gene="rlmH"
                     /locus_tag="RPH49_000927"
     CDS             complement(1780..2259)
                     /gene="rlmH"
                     /locus_tag="RPH49_000927"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020363758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDY5124109.1"
                     /translation="MKITILAVGKLKEKYWKQAIAEYEKRLGPYTKIDIIEVPDEKAP
                     ENMSDKEIEQVKEKEGQRILAKIKPQSTVITLEIQGKMLSSEGLAQELNQRMTQGQSD
                     FVFVIGGSNGLHKDVLQRSNYALSFSKMTFPHQMMRVVLIEQVYRAFKIMRGEAYHK"
     gene            complement(2627..4945)
                     /gene="adsA"
                     /locus_tag="RPH49_000928"
     CDS             complement(2627..4945)
                     /gene="adsA"
                     /locus_tag="RPH49_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored adenosine synthase AdsA"
                     /protein_id="HDY5124110.1"
                     /translation="MKALLLKTSVWLVLLFSAMGLWQVSSAAEQHTPMKAHAVTTIDK
                     ATTDRQLVLPTKEAAHQSGEEAATNVSASAQGTADDTNNKVTSNAPSNKPSTAVSTTV
                     NETHDVDAQQASTQKPTQSATFKLSNAKTASLSPRMFAANAPQTTTHKILHTNDIHGR
                     LAEEKGRVIGMAKLKTVKEQEKPDLILDAGDAFQGLPLSNQSKGEEMAKAMNAVGYDA
                     MAVGNHEFDFGYDQLKKLEGMLDFPMLSTNVYKDGKRAFKPSTIVTKNGIRYGIIGVT
                     TPETKTKTRPEGIKGVEFRDPLQSVTAEMMRIYKDVDTFVVISHLGIDPSTQETWRGD
                     YLVKQLSQNPQLKKRITVIDGHSHTVLQNGQIYNNDALAQTGTALANIGKVTFNYRNG
                     EVSNIKPSLINVKDVENVTPNKALAEQINQADQTFRAQTAEVIIPNNTIDFKGERDDV
                     RTRETNLGNAITDAMEAYGVKNFSKKTDFAVTNGGGIRASIAKGKVTRYDLISVLPFG
                     NTIAQIDVKGSDVWTAFEHSLGAPTTQKDGKTVLTANGGLLHISDSIRVYYDMNKPSG
                     KRINAIQILNKETGKFENIDLKRVYHVTMNDFTASGGDGYSMFGGPREEGISLDQVLA
                     SYLKTANLAKYDTTEPQRMLLGKPAVSEQPAKGQQGSKGSESGKDTQPIGKDKVMNPA
                     KQPATGKVVLLPTHRGTVSSGAEGSDCALEGTAVSSKSGKQLTKMSASKGSGHEKQLP
                     KTGTNQSSSPAAIFVLVAGIGLIATVRRRKAS"
     gene            complement(5171..5971)
                     /locus_tag="RPH49_000929"
     CDS             complement(5171..5971)
                     /locus_tag="RPH49_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDY5124111.1"
                     /translation="MSRLIRMSVLASGSTGNATFVENEKGSLLVDVGLTGKKMEELFS
                     QIDRNIQDLNGILVTHEHIDHIKGLGVLARKYQLPIYANEKTWQAIEKKDSRIPMDQK
                     FIFNPYETKSIAGFDVESFNVSHDAIDPQFYIFHNNYKKFTILTDTGYVSDRMKGMIR
                     GSDAFIFESNHDVDMLRMCRYPWKTKQRILGDMGHVSNEDAGHAMTDVITGNTKRIYL
                     SHLSQDNNMKDLARMSVGQVLNEHDIDTEKEVLLCDTDKAIPTPIYTI"
     gene            complement(6367..7155)
                     /locus_tag="RPH49_000930"
     CDS             complement(6367..7155)
                     /locus_tag="RPH49_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDY5124112.1"
                     /translation="MNWKLTKTLFIFVFILVNIVLVSIYVNKVNRSHINEVESNNEVN
                     FQQEEIRVPASILNKSVKGIQLEQITGRSKDFSSKAKGDSDLSTSDSGKLLNANISQS
                     VKVSDNNLKDLKDYVNKRVFKGAEYQLSEISSDSVKYEQTYDDFPILNNSKAMLNFKI
                     EDNKATSYKQSMMDDIKPTDGADKKHQVISVRKAIEALYYNRYLKKGDEVINARLGYY
                     SVVNETNVQLLQPNWEIKVKHDGKDKTNTYYVEATNNNPKIINH"
     gene            complement(7156..8490)
                     /locus_tag="RPH49_000931"
     CDS             complement(7156..8490)
                     /locus_tag="RPH49_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124113.1"
                     /translation="MNNKEHIKSVILALLVLMSVVLTYMVWNFSPDIANVDNTDSKKS
                     ETKPLTTPMTAKMDTTITPFQIIHSKNDHPEGTIATVSNVNKLTKPLKNKEVKSVEHV
                     RRDHNLMIPDLSSDFTLFDFTYDLPLSTYLGQVLNMNAKVPNHFNFNRLVIDHDADDN
                     IVLYAISKDRHDYVKLTTTTKNDHFLDALAAVKKDMQPYTDIITNKDTIDRTTHVFAP
                     SKPEKLKTYRMVFNTISVEKMNAILFDDSTIVRSSKSGVTTYNNNTGVANYNDKNEKY
                     HYKNLSEDEASSSKMEETIPGTFDFINGHGGFLNEDFRLFSTNNQSGELTYQRFLNGY
                     PTFNKEGSNQIQVTWGEKGVFDYRRSLLRTDVVLNSEDNKTLPKLESVRSSLANNSDI
                     NFEKVTNIAIGYEMQDNSDHNHIEVQINSELVPRWYVEYDGEWYVYNDGRLE"
     gene            complement(8483..10309)
                     /gene="walK"
                     /locus_tag="RPH49_000932"
     CDS             complement(8483..10309)
                     /gene="walK"
                     /locus_tag="RPH49_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDY5124114.1"
                     /translation="MKWLKQLQSLHTKLVIVYVLLIIIGMQIIGLYFTNNLEKELLDN
                     FKKNITQYAKQLEISIEKVYDEKGSVNAQKDIQNLLSEYANRQEIGEIRFIDKDQIII
                     ATTKQSNRSLINQKANDSSVQKALSLGQSNDHLILKDYGGGKDRVWVYNIPVKVDKKV
                     IGNIYIESKINDVYNQLNNINQIFIVGTAISLLITVILGFFIARTITKPITDMRNQTV
                     EMSRGNYTQRVKIYGNDEIGELALAFNNLSKRVQEAQANTESEKRRLDSVITHMSDGI
                     IATDRRGRIRIVNDMALKMLGMAKEDIIGYYMLSVLSLEDEFKLEEIQENNDSFLLDL
                     NEEEGLIARVNFSTIVQETGFVTGYIAVLHDVTEQQQVERERREFVANVSHELRTPLT
                     SMNSYIEALEEGAWKDEELAPQFLSVTREETERMIRLVNDLLQLSKMDNESDQINKEI
                     IDFNMFINKIINRHEMSAKDTTFIRDIPKKTIFTEFDPDKMTQVFDNVITNAMKYSRG
                     DKRVEFHVKQNPLYNRMTIRIKDNGIGIPINKVDKIFDRFYRVDKARTRKMGGTGLGL
                     AISKEIVEAHNGRIWANSVEGQGTSIFITLPCEVIEDGDWDE"
     gene            complement(10322..11023)
                     /locus_tag="RPH49_000933"
     CDS             complement(10322..11023)
                     /locus_tag="RPH49_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5124115.1"
                     /translation="MARKVVVVDDEKPIADILEFNLKKEGYDVYCAYDGNDAVDLIYE
                     EEPDIVLLDIMLPGRDGMEVCREVRKKYEMPIIMLTAKDSEIDKVLGLELGADDYVTK
                     PFSTRELIARVKANLRRHYSQPAQDTGNVTNEITIKDIVIYPDAYSIKKRGEDIELTH
                     REFELFHYLSKHMGQVMTREHLLQTVWGYDYFGDVRTVDVTIRRLREKIEDDPSHPEY
                     IVTRRGVGYFLQQHE"
     gene            complement(11643..11715)
                     /locus_tag="RPH49_000934"
     tRNA            complement(11643..11715)
                     /locus_tag="RPH49_000934"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11680..11682),aa:Asp,seq:gtc)
     gene            complement(11723..11797)
                     /locus_tag="RPH49_000935"
     tRNA            complement(11723..11797)
                     /locus_tag="RPH49_000935"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11762..11764),aa:Glu,seq:ttc)
     gene            complement(12226..13509)
                     /locus_tag="RPH49_000936"
     CDS             complement(12226..13509)
                     /locus_tag="RPH49_000936"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDY5124116.1"
                     /translation="MSSIVVVGTQWGDEGKGKITDFLAEQSDVIARFSGGNNAGHTIQ
                     FGGETYKLHLVPSGIFYKDKLAVIGNGVVVDPVALLKELDGLNERGIPTSNLRISNRA
                     QVILPYHLAQDEYEERLRGDNKIGTTKKGIGPAYVDKVQRIGIRMADLLEKETFERLL
                     KSNIEYKQAYFKGMFNETCPSFDDIFEEYYAAGQRLKEFVTDTSKILDDAFVADEKVL
                     FEGAQGVMLDIDHGTYPFVTSSNPIAGNVTVGTGVGPTFVSKVIGVCKAYTSRVGDGP
                     FPTELFDEDGHHIREVGREYGTTTGRPRRVGWFDSVVLRHSRRVSGITDLSINSIDVL
                     TGLDTVKICTAYELDGKEITEYPANLDQLKRCKPIFEELPGWTEDVTSVRTLEELPEN
                     ARKYLERISELCNVQISIFSVGPDREQTNLLKELW"
     gene            complement(13787..15187)
                     /gene="dnaB"
                     /locus_tag="RPH49_000937"
     CDS             complement(13787..15187)
                     /gene="dnaB"
                     /locus_tag="RPH49_000937"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDY5124117.1"
                     /translation="MDRMYEQNQMPHNNEAEQSVLGSIIIDPELINTTQEVLLPESFY
                     RGAHQHIFRAMMHLNEDNKEIDVVTLMDQLSSEGTLNEAGGPQYLAELSTNVPTTRNV
                     QYYTDIVSKHALKRRLIQTADSIANDGYNDELELDAILSDAERRILELSSSRESDGFK
                     DIRDVLGQVYETAEELDQNSGQTPGIPTGYRDLDQMTAGFNRNDLIILAARPSVGKTA
                     FALNIAQKVATHEDMYTVGIFSLEMGADQLATRMICSSGNVDSNRLRTGTMTEEDWSR
                     FTIAVGKLSRTKIFIDDTPGIRINDLRSKCRRLKQEHGLDMIVIDYLQLIQGSGSRAS
                     DNRQQEVSEISRTLKALARELECPVIALSQLSRGVEQRQDKRPMMSDIRESGSIEQDA
                     DIVAFLYRDDYYNRGGDEDDDDDGGFEPQTNDENGEIEIIIAKQRNGPTGTVKLHFMK
                     QYNKFTDIDYAHADMM"
     gene            complement(15219..15665)
                     /gene="rplI"
                     /locus_tag="RPH49_000938"
     CDS             complement(15219..15665)
                     /gene="rplI"
                     /locus_tag="RPH49_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDY5124118.1"
                     /translation="MKVIFTQDVKGKGKKGEVKEVPVGYANNFLLKKNYAVEATPGNL
                     KQLELQKKRAKQERQQEIEDAKALKETLSNIEVQVSAKTGEGGKLFGSVSTKQIAEAL
                     KAQHDIKIDKRKMDLPNGIHSLGYTNVPVKLDKEVEGTIRVHTVEQ"
     gene            complement(15662..17629)
                     /gene="gdpP"
                     /locus_tag="RPH49_000939"
     CDS             complement(15662..17629)
                     /gene="gdpP"
                     /locus_tag="RPH49_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP phosphodiesterase GdpP"
                     /protein_id="HDY5124119.1"
                     /translation="MNRQSTKKALLIPFVIMIITAIVLMGVWFIFNSLIALIASIVLV
                     VMIIVSIVLFRQALMKMDSYVDGLSAQISTTNNKAIKHLPIGIIVLDENDHIEWVNQF
                     MTDHMEANVISESVNEVFPNILKQLDRVKSVEIEYNQYHFQVRYSENDHCLYFFDITE
                     QVQTNELYENSKPIIATLFLDNYDEITQNMNDTQRSEINSMVTRVISRWATEYNIFFK
                     RYSSDQFVAYLNQKILADLEESKFDILSQLREKSVGYRAQLTLSIGVGEGTENLIDLG
                     ELSQSGLDLALGRGGDQVAIKSINGNVRFYGGKTDPMEKRTRVRARVISHALKDILAE
                     GDKVIIMGHKRPDLDAIGAAIGVSRFAMMNNLEAYIVLNETDIDPTLRRVMNEIDKKP
                     ELRERFITSDDAWDMMTSKTTVVIVDTHKPELVLDENVLNKANRKVVIDHHRRGESFI
                     SNPLLIYMEPYASSTAELVTELLEYQPTEQRLTRLESTVMYAGIIVDTRNFTLRTGSR
                     TFDAASYLRAHGADTILTQHFLKDDVDTYINRSELIRTVKVEDNGIAIAHGSDDKIYH
                     PVTVAQAADELLSLEGIEASYVVARREDNLIGISARSLGSVNVQLTMEALGGGGHLTN
                     AATQLKGVTVEEAIAQLQQAITEQLSRSEDA"
     gene            complement(17644..18582)
                     /locus_tag="RPH49_000940"
     CDS             complement(17644..18582)
                     /locus_tag="RPH49_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YybS family protein"
                     /protein_id="HDY5124120.1"
                     /translation="MGVAYVFSKIQPKATIIATIALVFVALALYLVPGLGLIFALFAT
                     IPGIVLWNKSIQSFGISALITVIITTVLGNTFVLSAIILVLIASLIIGQLLKERTSKE
                     RILYVTTVAMSLISLIAFMLLQTFGRIPPSASIVKPFKQTLHEAITMSGADANMTQIL
                     EEGFRQATVQLPGFIIIITFLIVLINLIVTFPILRKFKIATPVFKPLFAWQMSGILLW
                     IYIIVIICLLFTGQPSVFQSILLNFQLVLSLVMYIQGLSVIHFFGKAKGLPNAITILL
                     LIIGTILTPTTHIVGLLGVIDLSLNLKRIMKNNSKK"
     gene            complement(18877..19845)
                     /locus_tag="RPH49_000941"
     CDS             complement(18877..19845)
                     /locus_tag="RPH49_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDY5124121.1"
                     /translation="MTNYTVDALNLGKFITESGEVIDNLRLRYEHVGYHGQPLVVVCH
                     ALTGNHLTYGTDDYPGWWREIIDGGYIPIHDYQFLTFDVIGSPFGSSSPLNDPHFPKK
                     LTLRDIVRANERGIQALGYDKINILIGGSLGGMQAMELLYNQQFEVDKAIILAATSRT
                     SSYSRAFNEIARQAIHLGGKEGLSIARQLGFLTYRSSKSYDERFTPDEVVAYQQHQGN
                     KFKEHFDLNCYLTLLDVLDSHNIDRGRTDVTHVFKNLETKVLTMGFIDDLLYPDDQVR
                     ALGERFKYHRHFFVPDNVGHDGFLLNFSTWAPNLYHFLNLKHFKRK"
     regulatory      complement(19907..20005)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            complement(20210..20539)
                     /locus_tag="RPH49_000942"
     CDS             complement(20210..20539)
                     /locus_tag="RPH49_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDY5124122.1"
                     /translation="MITHMNMLILILLCGIVTLLIRIIPFIMISKVQLPDVVVRWLSF
                     IPITLFTALVIDSIIQQTPHGEGYTLNIPYIIALIPTVILSIITRSLTITIISGIVIM
                     AALRFFF"
     gene            complement(20536..21231)
                     /locus_tag="RPH49_000943"
     CDS             complement(20536..21231)
                     /locus_tag="RPH49_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDY5124123.1"
                     /translation="MATHLSFRQGVQECIPTLLGYAGVGISFGIVASSQNFSILEIIL
                     LCLVIYAGAAQFIMCALFIAGTPISAIVLTVFIVNSRMFLLSMSLAPNFKTYGFWNRV
                     GLGSLVTDETFGVAITPYLKGEAINDRWMHGLNITAYLFWAISCVAGALFGEYISNPQ
                     TLGLDFAITAMFIFLAIAQFESITKSRLRIYIVLIIAVIVMMLSLSMFMPSYLAILIA
                     ATISAALGVMMER"
     gene            complement(21882..23168)
                     /gene="serS"
                     /locus_tag="RPH49_000944"
     CDS             complement(21882..23168)
                     /gene="serS"
                     /locus_tag="RPH49_000944"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDY5124124.1"
                     /translation="MLDIRLFRNEPDTVKSKIELRGDDPKVVDEILELDEQRRKLISA
                     TEEMKARRNKVSEEIALKKRNKENADDVIAEMRTLGDDIKEKDSQLNEIDNKMTGILC
                     RIPNLISDDVPKGESDEDNVEVKKWGTPREFSFEPKAHWDIVEELKMADFDRAAKVSG
                     ARFVYLTNEGAQLERALMNYMITKHTTQHGYTEMMVPQLVNADTMYGTGQLPKFEEDL
                     FKVEKEGLYTIPTAEVPLTNFYRNEIIQPGVLPEKFTGQSACFRSEAGSAGRDTRGLI
                     RLHQFDKVEMVRFEQPEDSWNALEEMTTNAEAILEELGLPYRRVILCTGDIGFSASKT
                     YDLEVWLPSYNDYKEISSCSNCTDFQARRANIRFKRDKAAKPELAHTLNGSGLAVGRT
                     FAAIVENYQNEDGTVTIPEALVPFMGGKTQISKPVK"
     misc_binding    complement(23258..23474)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(23547..25061)
                     /gene="hutH"
                     /locus_tag="RPH49_000945"
     CDS             complement(23547..25061)
                     /gene="hutH"
                     /locus_tag="RPH49_000945"
                     /EC_number="4.3.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ammonia-lyase"
                     /protein_id="HDY5124125.1"
                     /translation="MTLYLDGETLTIEDIKSFLQQQSKIEIIDDALERVKKSRAVVER
                     IIENEETVYGITTGFGLFSDVRIDPTQYNELQVNLIRSHACGLGEPFSKEVALVMMIL
                     RLNTLLKGHSGATLELVRQLQFFINERIIPIIPQQGSLGASGDLAPLSHLALALIGEG
                     KVLYRGEEKDSDDVLRELNRQPLNLQAKEGLALINGTQAMTAQGVISYIEAEDLGYQS
                     EWIAALTHQSLNGIIDAYRHDVHAVRNFQEQINVAARMRDWLEGSALTTRQAEIRVQD
                     AYTLRCIPQIHGASFQVFNYVKQQLEFEMNAANDNPLIFEEANETFVISGGNFHGQPI
                     AFALDHLKLGVSELANVSERRLERLVNPQLNGDLPAFLSPEPGLQSGAMIMQYAAASL
                     VSENKTLAHPASVDSITSSANQEDHVSMGTTAARHGYQIIENARRVLAIECVIALQAA
                     ELKGVEGLSPKTRRKYEEFRSIVPSITHDRQFHKDIEAVAQYLKQSIYQTTACH"
     gene            25387..26199
                     /locus_tag="RPH49_000946"
     CDS             25387..26199
                     /locus_tag="RPH49_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDY5124126.1"
                     /translation="METLNSINIPKRKENSHKGDYGKILLIGGSANLGGAIMLAARAC
                     VFSGSGLITVATHPTNHSALHSRCPEAMVIDINDTKMLTKMIEMTDSILIGPGLGVDF
                     KGNNAITFLLQNIQPHQNLIVDGDAITIFSKLKPQLPTCRVIFTPHLKEWERLSGIPI
                     EEQTYERNREAVDRLGATVVLKKHGTEILFKDEDFKLTIGSPAMATGGMGDTLAGMIT
                     SFVGQFDNLKEAVMSATYTHSFIGENLAKDMYVVPPSRLINEIPYAMKQLES"
     gene            complement(26287..28956)
                     /gene="gyrA"
                     /locus_tag="RPH49_000947"
     CDS             complement(26287..28956)
                     /gene="gyrA"
                     /locus_tag="RPH49_000947"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDY5124127.1"
                     /translation="MAELPQSRINERNITSEMRESFLDYAMSVIVARALPDVRDGLKP
                     VHRRILYGLNEQGMTPDKSYKKSARIVGDVMGKYHPHGDLSIYEAMVRMAQDFSYRYP
                     LVDGQGNFGSMDGDGAAAMRYTEARMTKITLELLRDINKDTIDFIDNYDGNEREPSVL
                     PARFPNLLANGASGIAVGMATNIPPHNLTELINGVLSLSKNPDISIAELMEDIEGPDF
                     PTAGLILGKSGIRRAYETGRGSIQMRSRAVIEERGGGRQRIVVTEIPFQVNKARMIEK
                     IAELVRDKKIDGITDLRDETSLRTGVRVVIDVRKDANASVILNNLYKQTPLQTSFGVN
                     MIALVNGRPKLINLKEALVHYLEHQKTVVRRRTQYNLRKAKDRAHILEGLRIALDHID
                     EIISTIRESDTDKVAMESLQQRFKLSEKQAQAILDMRLRRLTGLERDKIEAEYNELLN
                     YISELEAILADEEVLLQLVRDELTEIRDRFGDDRRTEIQLGGFEDLEDEDLIPEEQIV
                     ITLSHNNYIKRLPVSTYRAQNRGGRGVQGMNTLEEDFVSQLVTLSTHDHVLFFTNKGR
                     VYKLKGYEVPELSRQSKGIPVVNAIELENDEVISTMIAVKDLESEDNFLVFATKRGVV
                     KRSALSNFSRINRNGKIAISFREDDELIAVRLTSGQEDILIGTSHASLIRFPESTLRP
                     LGRTATGVKGITLREGDEVVGLDVAHANSVDEVLVVTENGYGKRTPVNDYRLSNRGGK
                     GIKTATITERNGNVVCITTVTGEEDLMIVTNAGVIIRLDVADISQNGRAAQGVRLIRL
                     GDDQFVSTVAKVKEDAEDETNEDEQSTSTVSEDGTEQQREAVVNDETPGNAIHTEVID
                     SEENDEDGRIEVRQDFMDRVEEDIQQSSDEDEE"
     gene            complement(28993..30927)
                     /gene="gyrB"
                     /locus_tag="RPH49_000948"
     CDS             complement(28993..30927)
                     /gene="gyrB"
                     /locus_tag="RPH49_000948"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDY5124128.1"
                     /translation="MVTALSDVNNTDNYGAGQIQVLEGLEAVRKRPGMYIGSTSERGL
                     HHLVWEIVDNSIDEALAGYANQIEVVIEKDNWIKVTDNGRGIPVDIQEKMGRPAVEVI
                     LTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSQDLEVYVHRNETIYHQAYKKGVPQF
                     DLKEVGTTDKTGTVIRFKADGEIFTETTVYNYETLQQRIRELAFLNKGIQITLRDERD
                     EENVREDSYHYEGGIKSYVELLNENKEPIHDEPIYIHQSKDDIEVEIAIQYNSGYATN
                     LLTYANNIHTYEGGTHEDGFKRALTRVLNSYGLSSKIMKEEKDRLSGEDTREGMTAII
                     SIKHGDPQFEGQTKTKLGNSEVRQVVDKLFSEHFERFLYENPQVARTVVEKGIMAARA
                     RVAAKKAREVTRRKSALDVASLPGKLADCSSKSPEECEIFLVEGDSAGGSTKSGRDSR
                     TQAILPLRGKILNVEKARLDRILNNNEIRQMITAFGTGIGGDFDLAKARYHKIVIMTD
                     ADVDGAHIRTLLLTFFYRFMRPLIEAGYVYIAQPPLYKLTQGKQKYYVYNDRELDKLK
                     SELNPTPKWSIARYKGLGEMNADQLWETTMNPEHRALLQVKLEDAIEADQTFEMLMGD
                     VVENRRQFIEDNAVYANLDF"
     gene            complement(30937..32049)
                     /gene="recF"
                     /locus_tag="RPH49_000949"
     CDS             complement(30937..32049)
                     /gene="recF"
                     /locus_tag="RPH49_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDY5124129.1"
                     /translation="MKLNTLQLENYRNYDEVTLKCHPDVNILIGENAQGKTNLLESIY
                     TLALAKSHRTSNDKELIRFNADYAKIEGELSYRHGTMPLTMFITKKGKQVKVNHLEQS
                     RLTQYIGHLNVVLFAPEDLNIVKGSPQIRRRFIDMELGQISAVYLNDLAQYQRILKQK
                     NNYLKQLQLGQKKDLTMLEVLNQQFAEYAMKVTDKRAHFIQELESLAKPIHAGITNDK
                     EALSLNYLPSLKFDYAQNEAARLEEIMSILSDNMQREKERGISLFGPHRDDISFDVNG
                     MDAQTYGSQGQQRTTALSIKLAEIELMNIEVGEYPILLLDDVLSELDDSRQTHLLSTI
                     QHKVQTFVTTTSVDGIDHEIMNNAKLYRINQGEIIK"
     gene            complement(32046..32291)
                     /gene="yaaA"
                     /locus_tag="RPH49_000950"
     CDS             complement(32046..32291)
                     /gene="yaaA"
                     /locus_tag="RPH49_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDY5124130.1"
                     /translation="MIILVQEVVVEGDINLGQFLKTEGIIESGGQAKWFLQDVEVLIN
                     GVRETRRGKKLEHQDRIDIPELPEDAGSFLIIHQGEQ"
     gene            complement(32672..33805)
                     /gene="dnaN"
                     /locus_tag="RPH49_000951"
     CDS             complement(32672..33805)
                     /gene="dnaN"
                     /locus_tag="RPH49_000951"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDY5124131.1"
                     /translation="MMEFTIKRDYFITQLNDTLKAISPRTTLPILTGIKIDAKEHEVI
                     LTGSDSEISIEITIPKTVDGEDIVNISETGSVVLPGRFFVDIIKKLPGKDVKLSTNEQ
                     FQTLITSGHSEFNLSGLDPDQYPLLPQVSRDDAIQLSVKVLKNVIAQTNFAVSTSETR
                     PVLTGVNWLIQENELICTATDSHRLAVRKLQLEDVSENKNVIIPGKALAELNKIMSDN
                     EEDIDIFFASNQVLFKVGNVNFISRLLEGHYPDTTRLFPENYEIKLSIDNGEFYHAID
                     RASLLAREGGNNVIKLSTGDDVVELSSTSPEIGTVKEEVDANDVEGGNLKISFNSKYM
                     MDALKAIDNDEVEVEFFGTMKPFILKPKGDDSVTQLILPIRTY"
     gene            complement(34083..35444)
                     /gene="dnaA"
                     /locus_tag="RPH49_000952"
     CDS             complement(34083..35444)
                     /gene="dnaA"
                     /locus_tag="RPH49_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDY5124132.1"
                     /translation="MSEKEIWEKVLEIAQEKLSAVSYSTFLKDTELYTIKDGEAIVLS
                     SIPFNANWLNQQYAEIIQAILFDVVGYEVKPHFITTEELANYSNNETATPKETTKPST
                     ETTEDNHVLGREQFNAHNTFDTFVIGPGNRFPHAASLAVAEAPAKAYNPLFIYGGVGL
                     GKTHLMHAIGHHVLDNNPDAKVIYTSSEKFTNEFIKSIRDNEGEAFRERYRNIDVLLI
                     DDIQFIQNKVQTQEEFFYTFNELHQNNKQIVISSDRPPKEIAQLEDRLRSRFEWGLIV
                     DITPPDYETRMAILQKKIEEEKLDIPPEALNYIANQIQSNIRELEGALTRLLAYSQLL
                     GKPITTELTAEALKDIIQAPKSKKITIQDIQKIVGQYYNVRIEDFSAKKRTKSIAYPR
                     QIAMYLSRELTDFSLPKIGEEFGGRDHTTVIHAHEKISKDLKEDPIFKQEVENLEKEI
                     RNV"
     gene            36175..36312
                     /gene="rpmH"
                     /locus_tag="RPH49_000953"
     CDS             36175..36312
                     /gene="rpmH"
                     /locus_tag="RPH49_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDY5124133.1"
                     /translation="MVKRTYQPNKRKHSKVHGFRKRMSTKNGRKVLARRRRKGRKVLS
                     A"
     gene            36433..36786
                     /gene="rnpA"
                     /locus_tag="RPH49_000954"
     CDS             36433..36786
                     /gene="rnpA"
                     /locus_tag="RPH49_000954"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDY5124134.1"
                     /translation="MLLEKAYRIKKNADFQRIYKKGHSVANRQFVVYTCNNKEIDHFR
                     LGISVSKKLGNAVLRNKIKRAIRENFKVHKSHILAKDIIVIARQPAKDMTTLQIQNSL
                     EHVLKIAKVFNKKIK"
     gene            36925..38304
                     /gene="mnmE"
                     /locus_tag="RPH49_000955"
     CDS             36925..38304
                     /gene="mnmE"
                     /locus_tag="RPH49_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDY5124135.1"
                     /translation="MDLDTITSISTPMGEGAIGIVRLSGPQAVEIADILYKGKHLLND
                     VPSHTINYGHIIDPESKEVVEEVMVSVLRAPKTFTREDIIEINCHGGILTINRVLELT
                     MTYGARMAEPGEFTKRAFLNGRIDLSQAEAVMDFIRSKTDRASKVAMNQIEGRLSDLI
                     KKQRQSILEILAQVEVNIDYPEYDDVEDATTEFLLEQSKEIKQEINRLLDTGAQGKIM
                     REGLSTVIVGKPNVGKSSMLNNLIQDNKAIVTEVAGTTRDVLEEYVNVRGVPLRLVDT
                     AGIRETEDIVEKIGVERSRKALSQADLILFVLNNNEALTQEDYTLYEVVKNEDVIVIV
                     NKMDLEQNIDINEVKDMIGDTPLIQTSMLKQEGIDELEIQIRDLFFGGEVQNQDMTYV
                     SNSRHISLLKQARQTIQDAIDAAESGVPMDMVQIDLTRTWEILGEIIGETASDELIDQ
                     LFSQFCLGK"
     gene            38371..40248
                     /gene="mnmG"
                     /locus_tag="RPH49_000956"
     CDS             38371..40248
                     /gene="mnmG"
                     /locus_tag="RPH49_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDY5124136.1"
                     /translation="MVQEYDVIVIGAGHAGVEAGLASARRGAKTLMLTINLDNIAFMP
                     CNPSVGGPAKGIVVREIDALGGQMAKTIDKTHIQMRMLNTGKGPAVRALRAQADKVLY
                     QQEMKRVIEDEENLHIMQGMVDELIIEDNEVKGVRTNIGTEYLSKAVIITTGTFLRGE
                     IILGNMKYSSGPNHQLPSITLSDNLRELGFDIVRFKTGTPPRVNSKTIDYSKTEIQPG
                     DDVGRAFSFETTEYILDQLPCWLTYTNAETHKVIDDNLHLSAMYSGMIKGTGPRYCPS
                     IEDKFVRFNDKPRHQLFLEPEGRNTNEVYVQGLSTSLPEHVQRQMLETIPGLEKADMM
                     RAGYAIEYDAIVPTQLWPTLETKMIKNLYTAGQINGTSGYEEAAGQGLMAGINAAGKV
                     LNTGEKILSRSDAYIGVLIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLRLTDMGY
                     ELGMISEERYARFNEKRQQIDAEIKRLSDIRIKPNEHTQAIIEQHGGSRLKDGILAID
                     LLRRPEMTYDIILEILEEEHQLNADVEEQVEIQTKYEGYINKSLQQVEKVKRMEEKKI
                     PEDLDYSKIDSLATEAREKLSEVKPLNIAQASRISGVNPADISILLIYLEQGKLQRVS
                     D"
     gene            40248..40967
                     /gene="rsmG"
                     /locus_tag="RPH49_000957"
     CDS             40248..40967
                     /gene="rsmG"
                     /locus_tag="RPH49_000957"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDY5124137.1"
                     /translation="MTVEWLAEQLKEHNIELTETQKQQFQTYYRLLVEWNEKMNLTSI
                     TDEHDVYLKHFYDSVAPSFYFDFNQPISICDVGAGAGFPSIPLKIMFPQLKVTIVDSL
                     NKRIQFLNHLASELQLQDVSFIHDRAETFGKGVYRESYDVVTARAVARLSVLSELCLP
                     LVKKGGQFVALKSSKGEEELEEAKFAISVLGGNVTETHTFELPEDAGERQMFIIDKKR
                     QTPKKYPRKPGTPNKTPLLEK"
     gene            41010..41849
                     /gene="noc"
                     /locus_tag="RPH49_000958"
     CDS             41010..41849
                     /gene="noc"
                     /locus_tag="RPH49_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion protein"
                     /protein_id="HDY5124138.1"
                     /translation="MKKPFSKLFGLKNKDDIIGHIEEDRNSNVESIQIERIVPNRYQP
                     RQVFEPNKIKELAESIHEHGLLQPIVVRPIEEDMFEIIAGERRFRAIQSLNLPQADVI
                     IRDMDDEETAVVALIENIQRENLSVVEEAEAYKKLLEIGDTTQSELAKSLGKSQSFIA
                     NKLRLLKLAPKVLLRLREGKITERHARAVLSLSDSEQEALIEQVIAQKLNVKQTEDRV
                     RQKTGPEKVKAQNLRFAQDVTQARDEVGKSIQAIQQTGLHVEHKDKDHEDYYEIKIRI
                     YKR"
     gene            42058..>42141
                     /locus_tag="RPH49_000959"
     CDS             42058..>42141
                     /locus_tag="RPH49_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002458050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDY5124139.1"
                     /translation="MSSDTNSLAHTKWNCKYHIVFAPKYRRQ"
BASE COUNT        13014 a         7827 c         6630 g        14670 t
ORIGIN      
        1 tttgtgatta ttacacatta tcttatctgc tctttatcac cataaaaata gaaaaaacaa
       61 gattcctaaa gaatatagga atcttgtttc agactgtgga caaactgatt ttttatcagt
      121 tagcttattt agaaagtttt atttaaatta cagtttctat ttttattaga tcacaatttt
      181 attttagctc ttgttcaagt aatcattttt cgccaaaaac tttatactga atagcttcta
      241 cattaaatac tttgtcaatg agatcatcta catctttaaa ttcagaataa tttgcatatg
      301 gatctataaa ataaaattgt ggttctttac cggaaacatt aaatattctt aatattaaat
      361 atttctgctt atattctttc atagcaaaca tttcatttag cgacataaaa aatggttcct
      421 caatactaga agatgtagat gttttaattt caataaattt ttctacagct ttatctgtat
      481 ttgttggatc aaaagctact aaatcatagc catgaccgtg ttgagagcct ggattatcat
      541 ttaaaatatt cctaaactgt tctttcttat cttcgtctat tttattatca attagctcat
      601 taaagtaatt tagcgctaat ttttctccaa ctttaccggt taatttattc tctttatttg
      661 atttttcaat ttctgaatca tttttagtag tctttgatac acctttttta tattttggaa
      721 ttattccttt aggtgcttcc acttccttga gtgtcttatc tttttgtgct gttctaattt
      781 cttcaatttc gctgtcttcc tgtatttcgt ctatgctatt gaccaagcta tcataggatg
      841 tttttgtaac ttttgaagct aattcattaa atagttctaa aaatttcttt aaatcctcta
      901 gcatatcttc ttctgtgaat ccttcattca aatcataata tttgaatctt attgatccat
      961 gagaatatcc tgatggataa tcatttttta aatcataaga tgaatcttta ttttctgcgt
     1021 aataaaatct tccagtatta aattcatttg atgtaatata tttattgagt tcggaagata
     1081 aagttaatgc tctttgtttt gcagcatttt tatcccgcgg aaacatatac ttatctttga
     1141 ccatccttga ttcaaagata agtatatgcc ttctccttcc ggatgaaaaa gatataccaa
     1201 ataatatcca tcctttgttt cttttgttat attctcatca tatattgaaa tccaaggaac
     1261 tttactatag ttcccagtag caaccttccc tacaactgaa tatttatctt cttttatatg
     1321 cacttttaac tgcttgggta acttatcatg gactaaagtt ttatatagat cacctttatc
     1381 ccaatcagat tttttaacta cattattggt acgtttctct ttaattaatt taaggacctg
     1441 cataaagttg tctatcattt gaaattccct cctattataa aatatattat gtctcatttt
     1501 cttcaatatg tacttattta tattttaccg taatttacta tatttagttg cagaaagaat
     1561 tttctcaaag ctagaacttt gcttcactat aagtattcag tataaagaat atttcgctat
     1621 tatttacttg aaatgaaaga ctgcggaggc taactatgtc aaaaatcatg aacctcatta
     1681 cttatgataa gcttcttaaa aacataacag caattcacat aaacctcata tgttctgata
     1741 cattcaaaat ccctttatga agcggctgaa aaaaccgcat catttatgat atgcttctcc
     1801 acgcataatc ttaaatgctc tatacacttg ctcaattaac acaacccgca tcatttgatg
     1861 tgggaatgtc attttgctga atgatagtgc gtagttacta cgttgtaaga cgtccttgtg
     1921 caggccgttt gatccgccaa tgacgaatac aaagtcgctt tgcccttggg tcatgcgttg
     1981 gttcaattct tgggccaatc cttcggaaga tagcatcttt ccttgtattt ctaatgtaat
     2041 gactgttgat tgtggtttga ttttggctag tattcgttgg ccttcttttt cttttacttg
     2101 ctcaatttct ttgtcgctca tattttctgg tgctttttcg tctggaactt ctatgatgtc
     2161 tatcttggtg tatgggccta aacgtttttc atattctgct atggcttgct tccaatattt
     2221 ctcttttagt ttccctacag ctaaaatggt gattttcatg tcgtttggtc ctccaaattg
     2281 ttatcaactt tccagttatc cacaagttat taacttgttc acactgttcc ctcttattat
     2341 accaagtttt tttacagttt ttgatatttt cctgacattt atgcccggtt tttagtgtat
     2401 aacctgtgta tttgtggata actctgtggg cattgtgggt atttctcttt aaattgtaca
     2461 caattctgga taactatccc catttctgtg gataaatacc ttgatgtctt attacttatc
     2521 cccgttttta tttcccatat ttatcaacgg ttatagcttt tttccataaa aaaacactac
     2581 cgtacctctt atttaagaaa tacagtagta ttgttttcaa tatattttag ctagcttttc
     2641 tacgtcgtac agttgcgatt aaacctatac ctgctactaa tacaaatatc gctgctgggc
     2701 ttgaactttg attagttcca gtttttggta actgtttctc atgcccgcta cctttagacg
     2761 ctgacatttt agtcaattgt ttcccactct tacttgatac agcagttcct tctaatgcgc
     2821 aatcagaacc ttctgcaccg ctactaacag ttcctctatg cgttggtaac aacacaactt
     2881 tacctgtcgc tggttgtttc gctggattca tcactttgtc tttaccaatt ggttgtgtat
     2941 ctttaccaga ctcactacct ttgctacctt gttgtccttt agctggttgt tcacttactg
     3001 ctggtttacc taataacata cgttgtggtt ctgtcgtatc atacttagct aagttagctg
     3061 tttttaaata acttgctagt acttgatcta atgaaatacc ttcttctcta gggccaccga
     3121 acatactata tccgtcgcca cctgatgctg tgaagtcatt catcgttacg tgatatacac
     3181 gttttaaatc aatattttca aacttacctg tctctttatt taaaatttga atagcgttaa
     3241 ttcgtttgcc agatggttta ttcatatcat agtaaacacg gattgaatca gagatatgta
     3301 gtaaaccacc attcgctgtt aacactgtct taccatcttt ttgtgttgtt ggtgcgccta
     3361 aactatgttc gaaagcagtc cagacgtctg aaccttttac atcaatttgc gcaatcgtat
     3421 ttccaaatgg taatactgag attaaatcat agcgtgtcac cttacctttg gcgatagagg
     3481 cgcgaatacc tccaccattt gtcacggcaa agtcagtctt tttagagaaa ttcttaacgc
     3541 catatgcttc catagcatct gtaatcgcgt ttcctaaatt tgtttcacgc gttctaacgt
     3601 catctctttc tcctttgaaa tcaatggtat tgtttggaat aattacctct gcagtttgtg
     3661 ctctaaatgt ttgatcagct tgattaattt gttcagctaa tgctttgttc ggtgttacat
     3721 tttcaacgtc tttaacatta atcaatgacg gtttaatatt tgatacctct ccattgcggt
     3781 aattaaatgt aaccttaccg atattcgcaa gtgctgtacc tgtttgtgct aatgcatcat
     3841 tgttataaat ttgaccattt tgaagtacgg tatgtgaatg accatcaatg actgtaatac
     3901 gtttcttcaa ttgtggattt tgacttaatt gtttcactaa gtaatcgcca cgccatgttt
     3961 cttgtgttga aggatcaata cctaaatgtg atataacaac aaatgtatct acgtctttat
     4021 aaatacgcat catttccgct gtcacacttt gtaatggatc tctaaattca acacctttaa
     4081 tgccttcagg tcttgttttc gtctttgttt ctggtgtcgt tacgccaata attccataac
     4141 gaataccatt tttcgttaca atcgttgaag gcttaaatgc gcgttttcca tctttataaa
     4201 cgttagtact taacatcggg aagtctaaca taccctctaa ctttttcaac tggtcgtatc
     4261 caaagtcaaa ttcgtggtta cccactgcca tagcatcata acctactgca ttcatcgctt
     4321 tagccatttc ttcaccttta gactggtttg aaagtggtaa accttggaaa gcgtctcctg
     4381 cgtctaaaat taaatcaggc ttttcttgtt cttttactgt ttttaattta gccataccta
     4441 tgacacgccc tttttcttcg gctagtcggc catggatatc atttgtatgt aatattttat
     4501 gtgttgttgt ttgtggtgca ttagcagcaa acattcgtgg tgaaagtgat gctgttttag
     4561 catttgataa tttgaatgtt gctgattgag ttggtttttg tgttgaggct tgttgtgcat
     4621 ctacatcgtg cgtttcgttt actgttgttg aaactgctgt agatggtttg ttagatggtg
     4681 cgttggatgt tactttgttg tttgtatcat cagctgttcc ctgtgctgat gctgatacgt
     4741 tggttgccgc ttcttcacca gattgatgag ccgcttcctt tgttggcagt actagttgcc
     4801 tatctgttgt tgctttgtct atcgttgtta ctgcatgtgc tttcattggt gtatgttgct
     4861 cagccgcgct cgagacttgc cataatccca ttgcactaaa aagcaaaacg agccatacac
     4921 ttgttttaag taataaagct ttcatttcgt tccctccatt aactgtcata caccaatata
     4981 ttatcataat ccttatatta aaatgattga ttttatgtaa attatttata aattacattt
     5041 aatatcgaat tatttttcac atttcaacta gaaccttaat ttcaacaaca gccatttccc
     5101 accaacaaca taaaaaagca cccgataaag tcgtctcaca gcagtgccga actttatagg
     5161 gtactctcat ttatattgta tatattggcg ttggaatagc tttatccgta tcacatagca
     5221 atacttcttt ttccgtatca atatcgtgtt cgttcaatac ttgaccaaca ctcatacgcg
     5281 ccaaatcttt catattatta tcttgtgata aatgcgataa gtaaatacgt ttcgtgttac
     5341 ctgtaatcac gtctgtcatc gcatgacccg catcctcatt agatacatga cccatatcgc
     5401 ctaaaatacg ttgtttcgtc ttccatggat aacgacacat tctcaacata tcgacgtcat
     5461 gattactctc aaaaataaac gcatcgctgc cacgtatcat acctttcata cgatcagaca
     5521 cgtatcccgt atccgttaaa atcgtaaact tcttatagtt attatggaaa atataaaatt
     5581 gtggatctat cgcatcatgt gacacgttaa acgattcaac atcgaaacct gcaatagatt
     5641 ttgtttcata aggattaaaa atgaatttct gatccatagg gatgcgacta tctttctttt
     5701 caattgcctg ccaagtcttt tcattcgcat aaattggcaa ttgatattta cgcgccaaaa
     5761 cacctaatcc tttaatatga tcaatatgtt catgggttac taaaatacca tttaaatctt
     5821 gaatattacg gtcaatttga ctaaacaatt cttccatttt cttgccagtc aaaccaacat
     5881 caactaatag actacctttt tcattttcta caaaagtggc gttacctgta ctaccacttg
     5941 ctaatacact catgcgtatc aagcggctca tcctttctat ttaagcagtc aatctctcta
     6001 tatgactaca atatacatca gtacaaatat acgattttcc ctacagaaac tatcagtata
     6061 ttagctgttt tgtatacctt tcctattatg taactttagt tcatcgaccg gtttcttata
     6121 tttaaatttt gataatcacg tgcaatgaat ttcttaatta ttataacaat gattagacaa
     6181 atactaaagt ttttaaaata gcagttacac taattttaca atgcggtact acttaaaata
     6241 tgaataaatg cgcacgttgg agacacagaa atgtcgcctg tcagccataa taaaccgtac
     6301 cagcaaaaag ctagcactgc ttctcacata tgatgagctt gcaatgctag cttattacga
     6361 ttcatattaa tgattaataa ttttagggtt attatttgtc gcttcgacat agtaagtatt
     6421 cgttttgtcc ttaccgtcat gcttcacttt aatttcccag tttggttgta acaattgaac
     6481 attcgtttca ttcacgactg aatagtaacc aagtctagca ttaatgactt catcaccttt
     6541 tttcaagtaa cgattataat ataatgcctc gattgctttt ctcacactaa tcacttgatg
     6601 cttcttatct gcaccatctg tgggcttaat gtcatccatc attgattgtt tataactagt
     6661 cgctttgtta tcttctattt taaagttcaa catcgctttg ctgttattta aaatcggaaa
     6721 atcatcatac gtttgttcat attttacaga atctgaacta atctcgctta attgatattc
     6781 agcaccttta aatacgcgct tgttaacgta atcttttaaa tcttttaagt tattatcact
     6841 aacttttacc gattggctga tgttcgcatt taataatttt ccactatctg atgtggataa
     6901 atcagaatca cctttagctt ttgaactaaa gtcttttgat cgtcccgtaa tttgttctaa
     6961 ttgtatgcct ttaacagatt tatttaaaat actggctggc accctaattt cttcttgctg
     7021 aaaattaact tcattgttac tctcgacttc attaatgtgt gagcgattga ctttattaac
     7081 ataaatcgat actaacacga tgttgacaag aataaacacg aaaatgaaaa gtgtctttgt
     7141 cagtttccag ttcatttatt caagcctccc atcgttataa acataccatt cgccatcata
     7201 ttctacatac caacgcggta cgagttcact gttaatctgc acttcaatgt gattatgatc
     7261 tgagttatcc tgcatttcgt aaccgatagc gatgtttgtt actttttcaa aattaatatc
     7321 actattgttc gctaagcttg aacgtacaga ctctaatttc ggcaacgttt tattatcttc
     7381 actgtttaaa acaacgtcgg tgcgtaataa cgaacgacga taatcaaaga cgcctttttc
     7441 accccaagtg acttgaattt gattagagcc ttctttatta aacgttggat aaccgttaag
     7501 gaaacgttga tatgttaact cgcctgactg attattcgta ctaaacaatc tgaagtcttc
     7561 gtttaagaaa ccaccatgac cattaataaa atcaaaggtt cctggaatcg tttcttccat
     7621 tttgctggaa cttgcttcat cttcggacaa gtttttataa tgatattttt catttttatc
     7681 gttatagttt gcgacacctg tattattgtt gtaggttgta acaccactct ttgaactacg
     7741 aacgatggtt gaatcgtcaa atagtatagc attcattttc tcaacactaa tcgtgttaaa
     7801 taccatgcga tatgttttta acttttcagg tttacttggt gcaaaaacat gcgtcgtacg
     7861 atcaattgta tctttgtttg tgatgatatc tgtgtatggt tgcatgtctt ttttcactgc
     7921 tgctaatgca tctaaaaaat gatcattttt cgttgtagtt gttaatttta cgtaatcgtg
     7981 gcgatctttg cttatagcat aaagcacgat attatcatca gcatcatgat ctatgaccaa
     8041 acgattgaaa ttgaaatgat ttggtacttt cgcattcatg ttcagtactt ggccaagata
     8101 tgttgataac ggtaaatcat acgtaaaatc gaataatgta aaatcactgc tcaaatcagg
     8161 aatcatcaag ttatgatcac gacgaacatg ttccacggac ttcacttctt tattttttaa
     8221 aggtttcgtc agcttattca cattagaaac cgtcgcaatc gtaccttctg gatgatcatt
     8281 tttcgaatga ataatctgaa atggcgtaat agttgtatcc attttggctg tcataggtgt
     8341 cgttaaaggt ttcgtttcac tcttcttact atctgtattg tcgacatttg caatatcagg
     8401 agaaaagttc cataccatat atgtcaatac gacactcatc aagacaagta gcgctaaaat
     8461 gacagattta atatgctcct tattattcat cccaatcacc gtcttcaatg acttcacatg
     8521 gaagtgtgat aaagatagat gtaccttgac cttctacact gtttgcccaa atacgaccat
     8581 tgtgcgcttc cacaatctct ttcgaaatgg ctagtcctaa tccagtacca cccattttac
     8641 gcgtacgtgc cttatctaca cgatagaatc ggtcgaatat cttatcgact ttattgatag
     8701 gaataccgat gccattatct ttaatacgaa tcgtcattcg attataaagt ggattttgtt
     8761 tcacgtggaa ctcgacacgt ttatcgcctc tagaatattt catcgcattt gtaatgacat
     8821 tatcaaatac ttgcgtcatt ttatcaggat caaattctgt gaaaatcgtc tttttcggaa
     8881 tatctcgaat aaatgttgta tctttcgcag acatttcatg tcgattaata attttattaa
     8941 tgaacatgtt aaagtcgata atttctttgt tgatttgatc agactcatta tccattttag
     9001 ataactgtag caagtcattg accagtcgaa tcattcgttc tgtttcttca cgggtaacag
     9061 ataaaaattg tggcgcaagt tcctcatctt tccatgcacc ttcttcaagt gcttcaatgt
     9121 aactattcat agaagttaaa ggtgtacgta actcatgtga tacattagca acaaattcac
     9181 gacgctcacg ttcaacttgt tgttgttcag taacgtcatg taacacagcg atataaccag
     9241 ttacaaatcc tgtttcctgc acaatcgtac taaagttaac acgtgcgatt agaccttctt
     9301 cttcatttaa atctaataag aaactatcat tattctcttg aatttcttcc agtttaaatt
     9361 catcttcaag acttaataca cttaacatgt aatatccgat gatgtcttct tttgccatac
     9421 caagcatctt aagtgccata tcattgacga tacgaatacg tccacgacgg tctgttgcaa
     9481 taataccatc actcatatgg gtgataactg agtccagtct acgtttctca ctttcagtat
     9541 tagcctgcgc ttcttgtaca cgtttagaca agttattaaa tgctaaagct aattcgccaa
     9601 tttcatcatt accataaatc ttcacacgtt gcgtatagtt acctctggac atttcgaccg
     9661 tctggttacg catatcggtg attggtttgg taatcgttcg cgctataaag aatcctagga
     9721 tgactgtgat taataatgaa atagctgtac caacaatgaa tatttgattt atattattta
     9781 attggttata aacgtcatta atttttgatt cgatataaat attaccaatt acctttttat
     9841 cgactttaac ggggatatta tatacccaga cacggtcctt accaccgcca taatctttta
     9901 aaattaaatg atcgtttgat tgtcctagtg atagtgcttt ttggacagaa ctatcattcg
     9961 ctttttgatt gattagacta cggttagact gcttcgtcgt cgcaataata atttggtctt
    10021 tatctataaa acgaatttct ccaatttctt gacggttggc atactcactt aataaatttt
    10081 gaatatcttt ttgtgcattt acggagccct tttcgtcata tactttttca atactaattt
    10141 ctaattgttt agcgtactgc gtaatattct tcttaaaatt atcaagcagc tctttttcaa
    10201 gattatttgt aaaatacagc ccgataattt gcataccaat gataatcagt aatacataaa
    10261 caattacaag tttagtatga agggattgta gttgttttag ccacttcatt cgtttcgacc
    10321 tctactcatg ttgttggagg aaatatccaa cgcctctacg cgtcacaatg tattcaggat
    10381 gtgacggatc atcttcaatc ttttcacgta aacgacgaat cgttacatcg accgtacgta
    10441 catcgccaaa gtaatcatag ccccatactg tttgtaataa atgttcacgt gtcattactt
    10501 gtcccatatg ttttgataaa taatggaaca attcaaattc acgatgtgtt aattcaatat
    10561 cttcgccacg ttttttaata gaatatgcgt ctggataaat cacaatatct ttaattgtga
    10621 tttcattcgt cacgttccca gtgtcttgcg ctggttgtga gtaatgacgg cgtaaattcg
    10681 ctttcacacg tgcaattaat tcacgtgtac taaacggttt tgttacatag tcatctgcac
    10741 ctagttctaa accaagcact ttatcaattt ctgagtcttt agcagttagc ataataattg
    10801 gcatttcgta ttttttgcgc acttcgcgac atacttccat accatcacga ccaggtaaca
    10861 tgatatctaa taatacgatg tctggttctt cttcataaat taagtcgact gcatcattac
    10921 catcgtatgc acagtaaaca tcgtatcctt ctttttttaa gttaaattct aaaatatcag
    10981 caatcggttt ttcatcatca actacaacaa cttttctagc catttgcata aacctctttt
    11041 cttaaatcat taatattatt ttatcatttt ttgttcttta tcgtttatgt ttgtgtaaaa
    11101 aatcacagga tgtcgcttac tatttttgtt attgtgcgca ttttccatct tataacgtat
    11161 agtaacctat tatataattt accatttata agctattaat tctattttcc aatataaact
    11221 tatatattaa tattttttat tagtttctca cggcggattg tgacaatgat atttaacaca
    11281 atgatgaggt ctctattcca ataataaaat tagggtaatg gcaacttcta gttgcacgtc
    11341 attgctcaga aaataaatat cattattcat tattcgttac tttaacaatt gatgttatgg
    11401 aggattggtg gcatatcaca acgaagaaat atgttgacag tagcatatgt ttgtacgtct
    11461 aattaagatt ttattggcta cgtttatctt tcatatccaa ccactaagtt acttgaggtt
    11521 catacattat aaagaaaatg gacgaacaga taaatcaata tgattatcat tcgtccatat
    11581 atcttttatt aatataatat taaacgcaaa aaaatgccta tcctcttgga taggcatttg
    11641 tacggtctcg acgggaatcg aacccgcgat ctcctgcgtg acaggcaggc gtgttaaccg
    11701 ctacactacg agacctaaaa aatggtgact cctacgggac tcgaacccgt gttaccgccg
    11761 tgaaagggcg gtgtcttaac cgcttgacca aggagccgtt cttaagcaca agatagatta
    11821 tagcacagcc aatcttgcca tgacaagata ttttttacat aattttgcta ttattttttg
    11881 aagaatgtta taagtgaaaa attgcatttt attggctgtc tatttattat aataattacg
    11941 ctatttttga aatttttcta ttttaggtgc tttcatttac acttacgtct actctatttt
    12001 aatagctatt ttcgacatca gacttattac attcaagtat ttcttcttaa tttcgttaaa
    12061 tatcatctaa tcttttaaat tatgactagc aaatatcacc tttacgttag taatttttat
    12121 ctaaataatc gaatcgatac agaagcaaac ataacaaaag cctcctacca ttaaagatag
    12181 aaggctcatg tatttataat cattgtgtat gacttatata aagttctacc acaattcttt
    12241 taataggttt gtttgttctc tatctggacc aactgagaag atagaaattt gtacattaca
    12301 taattctgaa atacgctcta aatatttacg tgcattttca ggtaattctt ctaaagtacg
    12361 cacacttgtt acgtcttctg tccaacctgg taactcttca aagattggtt tacaacgttt
    12421 taattgatct aagtttgctg ggtattcagt aatttcttta ccgtctaatt cataagctgt
    12481 acagattttc actgtgtcta ggcctgttaa aacatcgatt gagttaatag ataaatctgt
    12541 aataccactt acacgacgag agtgacgtaa tacaactgaa tcaaaccaac ctacacgacg
    12601 tggacgtcct gttgttgtac cgtattcacg accaacctct ctaatatgat gtccatcttc
    12661 atcgaataat tcagtaggga atggaccatc accaacacgt gatgtataag ctttacatac
    12721 accaattacc ttcgaaacga atgtaggacc tacacctgta ccaacagtaa cgttacctgc
    12781 aattggatta cttgatgtaa cgaatggata tgtaccatgg tcgatatcta acattacacc
    12841 ttgcgcacct tcgaaaagta ccttttcatc tgctacaaat gcatcgtcta agatttttga
    12901 tgtgtctgtt acaaattctt ttaaacgttg acctgcagca taatattctt caaagatatc
    12961 atcaaatgat ggacatgttt cgttaaacat acctttgaaa tatgcttgtt tatattcaat
    13021 gtttgatttt aataatcttt cgaatgtttc tttttcaagt aaatctgcca tacgaatacc
    13081 gatacgttga actttatcta catatgctgg accgatacct tttttagttg taccaatctt
    13141 attatcacca cgtaaacgtt cttcatattc atcttgtgct aagtgatatg gtagaatcac
    13201 ttgcgcacga ttagatatac gtaaattact tgtaggaatg ccacgttcat ttaatccgtc
    13261 taattctttc aatagtgcaa ctggatcaac aacgactccg ttaccgatta ccgctaattt
    13321 gtctttgtaa aagataccag atggtactaa atgtaattta tatgtttctc cgccaaattg
    13381 aatggtatgg cctgcattat taccacctga aaaacgcgcg ataacatctg actgttctgc
    13441 caagaaatcc gttatttttc cttttccttc gtctccccat tgtgtcccaa ctactacgat
    13501 tgatgacatg tgagcacctc caagtttttc tcatttaacc atttgatatt ctaccaatat
    13561 cgagaccata atgcaaataa aaatcgaaca ttgattttcg gcctttttta aaagaaaacc
    13621 attttaacaa atcgtcttca acgtcctaaa aaccctttaa cagaggcgtt gccagtacta
    13681 attcatcact ttcaatacac aaacttaaca tatatcaacc cgttcagaac aaaataaaaa
    13741 ccgtacaatt ttatcattaa aatgattatt gtacggaaaa acttttttac atcatatcag
    13801 catgtgcata atcgatatct gtaaatttat tatattgttt cataaagtgt aacttaactg
    13861 tgcctgttgg accattacgt tgcttagcaa tgatgatttc aatttcaccg ttttcatcat
    13921 tcgtttgtgg ctcaaaacca ccatcatcgt catcatcttc atcgccgcca cggttatagt
    13981 aatcatcacg gtataagaat gcaacgatat cggcatcttg ctcaatcgaa ccagattcac
    14041 gaatatcact catcattgga cgtttatctt gtcgttgttc aacaccacga gataactgac
    14101 tcaacgcgat aactggacat tctaattcac gggctaatgc ttttaatgta cgagagattt
    14161 cagaaacttc ctgttgtctg ttatcagacg cacgtgaacc actaccttga atcaactgta
    14221 agtagtcaat cacaatcatg tctaagccat gttcttgctt taatcgacga catttagaac
    14281 gtagatcatt aattcgaata cccggtgtat catcaataaa aatcttcgta cgtgataatt
    14341 tacctaccgc tatagtaaaa cgactccaat cttcctcagt catagtaccc gttcttaagc
    14401 ggtttgagtc aacattacca gaactacaaa tcatacgtgt ggctaactga tcagcaccca
    14461 tctctagtga gaaaatacca actgtataca tatcttcatg cgttgcaact ttttgtgcaa
    14521 tattaagtgc gaacgcagtc ttacctacag atggacgcgc tgcaaggata attaaatcat
    14581 ttcggttgaa ccctgctgtc atttggtcta aatctcgata tcctgtagga atacctggtg
    14641 tttgaccact attttgatca agctcttcag ctgtttcata tacttgtcct aagacgtctc
    14701 gaatgtcttt aaagccatcg ctttcacgag aagatgatag ctctaaaatt cgacgttctg
    14761 catcacttaa aatcgcatct agttcaagtt catcattata tccatcattg gcaatactat
    14821 ctgcagtttg aatcaatcta cgttttaatg catgcttaga aacaatgtcc gtataatact
    14881 gaacatttcg tgtcgttggt acatttgtag ataactctgc aagatattgc ggaccacccg
    14941 cttcattcaa cgtaccttca cttgataact gatccatcaa tgttactaca tcaatttctt
    15001 tgttatcttc atttaagtgc atcattgcac ggaaaatatg ttgatgggca cccctataaa
    15061 acgactcagg aagcaaaact tcctgagtag tattaatcaa ttctggatct ataataattg
    15121 aacctaagac agactgttca gcttcattgt tatgcggcat ttgattttgc tcatacattc
    15181 tatccatgaa tggttacacc tcttatttca atccaacttt attgttcaac tgtgtgtacg
    15241 cgaatcgtac cttcaacttc tttatctaat ttaacaggta cattcgtata tcctagggaa
    15301 tgaattccat ttggtaaatc cattttacgt ttatcaattt taatatcatg ttgtgctttt
    15361 agtgcttcgg caatttgttt tgtacttact gacccaaaca atttaccacc ttcaccagtt
    15421 tttgctgata cttgaacttc aatgtttgat aacgtttctt ttaatgcttt agcatcttca
    15481 atttcttgtt ggcgttcttg ttttgcacgt tttttctgta actctaattg tttaaggtta
    15541 cctggtgttg cttctacagc ataattcttt ttcaataaga agttatttgc ataacctact
    15601 ggtacttctt taacttcacc ttttttacct ttacctttaa catcttgtgt aaaaattact
    15661 ttcatgcatc ttcactccta cttaattgtt ctgtaattgc ttgttgtaat tgtgctatcg
    15721 cctcttcgac tgtcacacct ttaagttgtg ttgccgcatt ggttaaatgt ccaccgccac
    15781 caagtgcttc cattgttaac tggacattta ctgaaccgag tgaacgtgca gatataccaa
    15841 ttagattatc ttcacgtctc gcaacaacat atgatgcttc aataccttct aaacttaaca
    15901 gttcatctgc tgcttgtgca actgttactg gatgataaat tttatcgtct gaaccatgcg
    15961 caatggctat gccattatct tcgactttta cagttcgaat taattcagat cgattaatat
    16021 aagtatccac atcatctttt aagaaatgtt gcgttagaat cgtatctgca ccatgtgcac
    16081 gtaaataact cgctgcatcg aatgttcttg atcctgttcg taatgtaaag tttcttgtat
    16141 ctacaataat acctgcatac atcactgttg attcaagacg tgttaaacgt tgttctgttg
    16201 gttgatattc cagtaattct gttacaagtt ctgctgttga acttgcgtat ggttccatat
    16261 atatcaacaa tggattagag atgaagcttt caccacgtct atgatgatcg ataacaactt
    16321 tacggtttgc tttatttaaa acattttcat ctaaaaccag ttccggttta tgcgtatcaa
    16381 caatcactac agttgtctta gatgtcatca tatcccaagc atcatctgat gttataaatc
    16441 gttctcttaa ctctggcttt ttatcaattt cgttcatcac gcgtcgtaat gttggatcaa
    16501 tgtcagtctc atttaatacg atgtatgctt ctaaattatt catcattgca aatctagaca
    16561 caccgattgc tgcaccaatt gcatctaagt caggacgttt atgtcccatg ataatgactt
    16621 tgtcaccctc tgcaaggata tcttttaacg catgtgagat cacacgtgct cttacacgag
    16681 tacgtttctc catcgggtca gtcttaccgc catagaaacg cacattacca ttaatacttt
    16741 taattgcaac ttggtcgcca ccgcgtccta atgctaagtc taggcctgat tgtgataatt
    16801 cacctaagtc gattaaattt tcagtacctt caccaacacc aatacttaat gttaattggg
    16861 cacgataacc aacacttttt tcacgtaatt gactcaagat atcaaattta gattcttcta
    16921 agtcagctaa tattttttga tttaaatagg ctacgaattg atcagaacta taccttttaa
    16981 agaatatatt atactcagtt gcccatcgac taataacacg cgttaccatt gaattgattt
    17041 ccgaacgctg cgtatcattc atattttgag taatctcatc gtagttatct aaaaataatg
    17101 tcgcaatgat tggtttagaa ttttcatata gttcatttgt ttgtacttgt tcagttatat
    17161 caaagaaata gaggcagtga tcattctcag aataacgtac ttggaaatga tactgattat
    17221 attctatttc aacggatttc actctatcta attgctttaa aatgtttgga aatacttcat
    17281 ttacagattc agaaatgaca tttgcttcca tatgatctgt cataaattgg ttaacccatt
    17341 cgatgtgatc attttcatct aaaacaatga taccaattgg taaatgtttg attgctttat
    17401 tatttgttgt tgaaatttga gcactcaaac catctacata actatccatt ttcattaaag
    17461 cttgtctgaa taaaacgatg ctaacaataa tcatcacgac aagaacgata gatgcaatta
    17521 gtgctataag actattaaag ataaaccata cacccattaa aacaattgct gtgatgatca
    17581 tgatgacaaa tggtattagt aaagctttct tagtggactg ccgattcatt attccacctc
    17641 tattcacttt ttagaattat ttttcatgat tcgcttcaaa ttcaaactta aatcgataac
    17701 accaagtagt cctacaatat gtgtcgtagg tgtcagtatt gtaccgataa tcaatagtaa
    17761 aatcgttatt gcattcggca aacctttcgc tttaccaaag aaatgaataa cacttaaacc
    17821 ttgaatatac attactaatg ataacacaag ttggaagttt aaaagaatgc tctggaacac
    17881 actcggttga cctgtaaata ataaacatat gataacaata atgtatatcc ataataaaat
    17941 accgctcatt tgccacgcga aaagtggctt aaatacaggt gtagcgattt taaattttcg
    18001 taaaatcgga aatgtaacga ttaagttaat taagacgatt aaaaatgtaa tgataatgat
    18061 gaaacctggt aattgaacgg tcgcttgtct aaacccttct tctaatattt gggtcatatt
    18121 cgcatcggca ccgctcatcg taatcgcttc atgtaatgtt tgcttgaaag gttttactat
    18181 gctcgctgat ggtggaattc ttccgaatgt ttgtagtaac ataaaagcga ttaatgaaat
    18241 taagctcatc gctactgttg ttacgtataa tattctttct ttagacgttc tttctttgag
    18301 caattgacca ataattaaac ttgcaattaa gactaatatg atggcactta aaacgaaagt
    18361 attacctaaa acagttgtta taattactgt aataagtgca ctaatcccga aagattgtat
    18421 tgatttattc cataaaacga tacctggtat ggttgcaaat aatgcaaata ttagtcctaa
    18481 accaggcact agatataaag ctaaagcgac aaataccaac gcaatcgttg caattattgt
    18541 tgctttaggt tgtatttttg aaaacacata agccactccc atatttttaa ctatagctat
    18601 tattttaacc tctttaatgg aatttaacaa tttatagatt gtatgcttct atttcattta
    18661 attgaataat aactttcatg ttttataagt aattaacata ctcatttgaa tcgcttttgt
    18721 gtgctttcat tttcaacatg attatttaat cccactacat agcaatcaag cttgatttag
    18781 atttacaatt catttccact ctcatgtact ctagatgtct ttgaatatga taactgtgat
    18841 ttagtggctt cattttttga aaatatatac atattattac ttacgcttaa aatgctttaa
    18901 atttaagaaa tgatataagt taggtgccca ggtactaaaa tttagtagga atccatcatg
    18961 cccaacatta tcaggcacga agaaatgacg atgatattta aaacgttcac ctaatgcacg
    19021 aacttgatca tccggatata gcaaatcatc tatgaacccc atcgttaaca cttttgtttc
    19081 taaattttta aaaacatgcg ttacgtctgt gcgacctcgg tcaatgttgt gactatccaa
    19141 tacatctagc agtgtcagat aacaattcaa atcaaaatgt tctttaaatt tattaccttg
    19201 atgttgttgg tatgcgacta cttcatccgg cgtgaaacgt tcatcataac tttttgatga
    19261 tcgatatgtc aaaaaaccta attggcgtgc aatacttaga ccttccttac caccaagatg
    19321 aatggcttgc cttgcaattt cattgaaagc tctactataa gatgatgttc gacttgttgc
    19381 agcaaggata atggctttat ctacttcaaa ctgttgattg taaagtagtt ccattgcttg
    19441 catacctcca agacttcccc ctattaaaat attaatctta tcataaccaa gggcttgtat
    19501 acctcgttca ttcgctctga ctatatctct taatgttaat tttttaggaa aatgagggtc
    19561 gtttaaaggt gaacttgaac cgaaaggact accaataaca tcaaatgtta aaaattgata
    19621 atcgtgaatg ggtatatatc ccccatcaat aatttctcgc caccaacccg gataatcatc
    19681 tgttccatat gttaaatgat tgccagttaa tgcatgacaa actacaacta atggttgtcc
    19741 atgataaccg acatgctcat atctcaaacg caagttatct atgacttccc cagattctgt
    19801 aataaatttc cctaaattta aagcatctac tgtgtaattt gtcattgttc tttcctcctt
    19861 aaacaaaaaa aaacttctca ccctattgaa aagtaagaag tctttatact tatcattcga
    19921 gtaactcgtt ggttttagca ccgtgctata aagtcggttg ctgaagtatc acagggccaa
    19981 gtccctcaac ttctcacaat aagaaatatg aaattgttat gtgttagttg agattcagtg
    20041 atgaattact tttatcattt aaaatgttgt tatcattgtc atgcgttagc caaatcgctt
    20101 acgtatacac gattcccaat cttaacatag acgatttgta tatcagaatt ttctgattac
    20161 taacagttta cctaagttta aatatctgtt caatgatttt cagttatttt taaaagaaaa
    20221 atcgtaatgc tgccatgata acaatcccac taataattgt aatagttaaa ctacgcgtga
    20281 ttatagataa aataaccgtc ggaatgagcg cgataatgta agggatgttt aatgtatacc
    20341 cctcaccatg aggcgtctgt tgaataatgc tgtctatgac aagtgccgta aatagtgtga
    20401 ttgggataaa tgatagccat cgaaccacga catcaggcaa ttgcactttt gaaatcatga
    20461 taaaaggtat aattcgaatt aatagcgtta cgataccaca caataaaata agtattaaca
    20521 tgttcatatg agttatcatc gttccatcat cactcctaac gctgctgaaa ttgtggctgc
    20581 aattaatatt gctagatatg aaggcataaa catacttagc gataacatca ttactatgac
    20641 ggcaataatg agtactatgt aaattcttaa tcgcgattta gtaattgatt caaattgcgc
    20701 aatggccaaa aagataaaca tagccgtgat agcaaaatct aaccctagcg tttgcggatt
    20761 tgagatatat tcgccaaata aagccccagc tacacatgaa attgcccaaa ataaatatgc
    20821 tgtgatatta agaccatgca tccaacgatc attgatagct tctcctttta aataaggtgt
    20881 aatggcgacg ccaaacgttt cgtcagttac taatgaacct aatccaacac ggttccaaaa
    20941 cccatatgtc ttgaagtttg gtgcaagcga catacttaaa aggaacattc ttgaatttac
    21001 gataaataca gttagtacaa tcgctgatat cggtgtacct gctataaaca acgcgcacat
    21061 aataaattgc gcagcaccgg catatataac aagacataac aagataattt ctaaaatact
    21121 aaagttttga gacgaagcca caataccaaa tgaaatacca acaccggcat aacccaataa
    21181 tgttgggata cactcttgta cgccttgtct aaaacttaaa tgtgttgcca tctcaattac
    21241 ctcctttgcc actttatctt tatataatta cgaaaaaata atatacctag tctaatacag
    21301 ttctataccc taagcaataa cattagactc cagtttgtct gaggttagac atactggagt
    21361 cttcaatcag ctttatatca actttttatt tttgagaatt ttcatttttt tatttaagac
    21421 tacctccata ttttctacgg atttgtagtt gtttttaagt actaatttta taatttttta
    21481 tatctaatga tgagtctggg atattgattc atgtaacact cccttataat catcatcctc
    21541 tccccctacc ctactccatc gatattactc atactacatc aacgaaatca gttttttatc
    21601 acttaatttc ctataatagt gatgctcaaa attgttacgt tttagattgt tttagttcat
    21661 cataattatc ccgtattgtt gctataatga aatgcgttca ccccattaaa ccacaaactt
    21721 aatttattgt tgttatgtgc attggctcac tattatactt ttacagcaca aaaaaagtgg
    21781 cgacagcttc gtcaccactt tttaaaatat tatttaaagt atcttgccct tgctttaagt
    21841 atacgtagat atatactttt taaagcttgt agctaaagcc tttatttaac tggttttgaa
    21901 atttgtgttt taccacccat aaatggtact aatgcttctg gaattgttac tgttccatct
    21961 tcattttggt aattttcaac aatagcagca aatgtacgtc caactgctaa accactacca
    22021 tttaatgtat gtgctaattc tggtttagct gctttgtcac gcttgaagcg gatgttagca
    22081 cgacgcgctt ggaaatccgt acagtttgag catgaactaa tttctttata atcattgtag
    22141 cttggtaacc aaacttctaa atcatatgtt ttgcttgcac taaatccaat atcacctgta
    22201 cataaaataa cacgacggta tggtaaacct aactcttcta gaattgcttc tgcgtttgtt
    22261 gtcatttctt ctaaagcatt ccatgaatct tcaggttgtt caaaacgtac catttccact
    22321 ttatcgaatt gatgtaaacg aattaatcct cttgtatctc tacctgctga tcctgcttca
    22381 ctacggaaac atgcagattg accagtgaat ttttcaggaa gtacacctgg ttgaataatt
    22441 tcattacggt agaaattcgt taatggtact tcagcagttg gaattgtata taatccttct
    22501 ttttctactt taaataaatc ttcttcaaat ttaggtaatt gacctgtacc atacattgta
    22561 tctgcgttca caagctgtgg taccatcatt tctgtataac catgttgtgt tgtatgtttt
    22621 gtaatcatat agttcattaa agcacgctct aattgcgcac cttcatttgt taaatataca
    22681 aaacgcgcac ctgaaacttt tgctgcacga tcaaaatcag ccattttcaa ttcttctaca
    22741 atatcccaat gtgctttggg ttcaaatgaa aactcacgtg gtgtacccca ctttttaact
    22801 tcaacgttat cttcatcaga ttcaccttta ggtacatcat cacttattaa atttggaata
    22861 cgacaaagga tacctgtcat tttattatca atttcattta attgactatc tttttcttta
    22921 atatcgtcac ctaatgtgcg catttcagca atcacatcat cagcattttc tttattacgt
    22981 ttttttaatg cgatttcttc gcttacttta ttacgacgtg ctttcatttc ttctgttgca
    23041 ctaattaatt tacgtcgttg ctcatccaat tctaaaattt catctacaac ttttggatca
    23101 tctccacgta attcaatttt gctcttaact gtgtcaggct catttctgaa taatctaatg
    23161 tctaacatta accttcatcc tttcccaaat aattatcatt tattatggaa tgacgtacgt
    23221 ctttattttt tagaaaataa aaaaagacca catccctaca agggacgtgg tctacgcgtt
    23281 gccaccctat ttaacaattt aagttataaa gatacactaa acctaaattg cacttcacta
    23341 aaataacggt tatcaccgat tgttctttta aattaagtag gtagattcat atatatgttg
    23401 attcttgttc acactaacca caagctctct gatatcgaac actatatatt acttgtccta
    23461 cgaacaatgt cttattaagt tatttttaat atagcaaact atatttgctt tttcaagtaa
    23521 cgatttcaaa catcactcat gtcgatttag tgacatgcag tcgtttgata aattgattgc
    23581 tttaaatact gtgcaaccgc ttcaatatct ttatgaaatt gacggtcatg tgtaatggat
    23641 ggcacgatac ttcgaaactc ctcatattta cgacgtgttt ttggtgataa accttcaaca
    23701 ccttttaact ctgctgcttg taatgcaata acacattcga ttgccagcac acgtcttgca
    23761 ttttcaataa tttgataacc atgtctagca gctgtagttc ccatagatac gtgatcttct
    23821 tggttcgcag atgaagtgat agaatcaaca ctcgctggat gcgctaaagt tttattttca
    23881 gaaacgagac ttgcagcagc atattgcata atcatcgcgc cactttgcaa tcctggctct
    23941 ggactaagaa atgctggtaa atcaccattt aattgaggat ttactagtcg ctctagacga
    24001 cgttccgata cgtttgctaa ttcacttaca cctaatttaa gatgatctaa tgcaaaagca
    24061 ataggttgtc catggaagtt accacctgaa ataacaaacg tttcatttgc ttcctcaaat
    24121 ataagtggat tatcattagc cgcattcatt tcaaattcta attgctgttt aacataattg
    24181 aatacttgaa aactcgcgcc atggatttgt ggtatacaac gcaacgtata tgcatcttgt
    24241 acacgtattt ctgcttgtcg cgttgttaat gctgatcctt ctaaccaatc acgcatacgc
    24301 gctgccacat taatctgttc ttgaaaatta cgaacagcgt gcacatcatg tcgatatgca
    24361 tctataatgc cattaagaga ctgatgcgtt aatgcagcaa tccattcaga ttggtaacct
    24421 aaatcttctg cttctatata actaatgaca ccttgagctg tcatagcttg cgtaccatta
    24481 atcaatgcta aaccttcttt agcctgaagg ttcaaaggtt gtctatttaa ttctcttaat
    24541 acatcgtcac tatccttttc ttcccctctg tacaatactt tcccttcacc aattaatgct
    24601 aatgctaagt gtgataatgg cgctaaatct cctgatgcac cgagagagcc ttgctgtggg
    24661 attatcggta taatacgttc atttataaaa aattgtaatt gtctcactaa ttctaaagtg
    24721 gcacctgaat gaccttttaa taatgtattc aatcgtaaaa tcatcatgac taatgctact
    24781 tcttttgaaa atggctcacc tagtccacag gcatgtgagc gtatcagatt cacttgtaat
    24841 tcattatatt gcgtcgggtc tatacgtaca tcactaaata acccaaaacc tgtagtaata
    24901 ccgtaaaccg tttcctcatt ttcaataata cgttcaacta ccgctctact ttttttgaca
    24961 cgttctaacg catcatcaat aatttcaatc tttgattgtt gttgtaaaaa tgatttaata
    25021 tcctcaattg ttagtgtctc accatctaaa tataaagtca tatatgttac ccccttgttt
    25081 atattaagta acccatcctt cttgaagtat acgttttcat ttttattgaa acaatggttt
    25141 tacgtacatt tataacctat tatcagagca ctattgtagt gcgttaaagg atattaagat
    25201 tgttgtaagc atatttaata atttatctat tgacgaattg catatacagg tatagtattt
    25261 tctattgtat ttaacgacaa ataataatga attcagaaat ttataataca ttttgttaaa
    25321 agttactatg tatttttaaa attgaataaa ttcggaaaag gcttttacat gggaggttat
    25381 atcactatgg aaacgttaaa ttctattaac attcctaagc gtaaagaaaa ttcacataaa
    25441 ggtgattatg gcaaaatttt attaattggt ggatctgcta acttaggtgg tgccattatg
    25501 ttagcggctc gtgcatgtgt atttagcggt agtggtttaa tcactgtagc tacacatcca
    25561 acaaatcatt cagcattaca ttctcgttgc ccagaagcga tggttattga tattaatgat
    25621 acgaaaatgt tgacgaaaat gattgaaatg actgacagta tactaattgg tccaggtctt
    25681 ggcgttgatt tcaaaggaaa taatgccatt acattcctac tacaaaatat acaaccgcat
    25741 caaaatttaa tcgtagacgg cgatgcgatt acaatcttta gtaaactgaa accgcaatta
    25801 cctacatgtc gcgtgatttt tactccgcat ctcaaagaat gggagcgatt aagtggtatt
    25861 cctattgagg aacagacata tgagcgtaat cgtgaagcag ttgatcgttt aggcgcaact
    25921 gttgtactta aaaaacatgg tactgaaatt ttatttaaag atgaagactt taaattgaca
    25981 atcggtagtc cagcaatggc gactggtggt atgggcgata cacttgctgg tatgattaca
    26041 agttttgtcg gtcaatttga taacttaaaa gaagcggtta tgagtgccac atatacacat
    26101 agttttattg gcgaaaacct tgcaaaagat atgtatgtgg taccaccatc aagacttatc
    26161 aatgaaatac cttacgcaat gaaacaatta gaaagttagt cattactaat cattgaatat
    26221 agtaaagcat tactttctag cacaaaaata agacttccct acatataggg aagtcttatt
    26281 tttttattat tcttcatctt catctgatga ttgttgtata tcttcttcaa cacgatccat
    26341 gaaatcttgt cttacttcaa tacgtccatc ttcatcattt tcttctgaat caatcacttc
    26401 agtatgaatt gcatttcctg gtgtttcatc atttacaacc gcttcacgtt gttgttcagt
    26461 accatcttca gatacagttg aagtagattg ctcatcttca ttcgtttcat cttctgcatc
    26521 ttcttttact ttagcaaccg ttgaaacaaa ttgatcatca cctaagcgaa ttaagcgaac
    26581 accttgtgct gcacgaccat tttgagaaat atctgcaaca tctagtcgaa taatgacacc
    26641 tgcattagta acaatcatta aatcttcttc accagttact gtagtgatac atacaacatt
    26701 accattacgc tcagtaatcg tagctgtttt aataccttta ccaccacgat ttgataaacg
    26761 atagtcatta actggcgtac gtttaccata accattttca gtaactacta atacttcatc
    26821 aacactgttt gcatgagcta catcaagccc tacaacttcg tcaccttcac gaagtgtaat
    26881 acctttcaca cccgttgctg tacggcctaa aggacgtaat gttgattcag ggaatcgaat
    26941 taatgatgca tgtgatgtac caatcaagat atcttcttga ccacttgtta agcgaactgc
    27001 aattaactca tcatcttctc tgaacgaaat cgcaatctta ccatttctat ttattcttga
    27061 gaagttactt aatgctgaac gtttaacgac accacgttta gttgcaaaca ctaagaagtt
    27121 gtcttcactt tcaaggtctt taacagcaat cattgtacta atgacttcat cattttcaag
    27181 ttcaatagca ttcactacag gaataccttt agactgtctt gataactcag gcacttcata
    27241 acctttaagt ttgtatacac gacctttgtt agtaaagaac aatacatggt catgtgtact
    27301 taaagttacc aattgactga caaaatcttc ttccaatgtg ttcatacctt gaacaccacg
    27361 accaccacgg ttttgagcac gatatgtaga taccggcaaa cgtttaatgt agttattatg
    27421 gctcaaagta attactattt gttcttctgg aattaagtct tcatcttcta agtcttcaaa
    27481 tccacctaat tgaatttctg tacgacgatc atcaccgaaa cgatctctaa tttcagtcaa
    27541 ttcatctcta actaactgta ataacacttc ttcatcagct aagattgctt ctaattcact
    27601 aatataattt aataactcat tatattcagc ttcaattttg tctctctcta aacctgttag
    27661 acgtcttaaa cgcatgtcta aaatagcttg agcttgtttt tcagaaagtt tgaagcgttg
    27721 ttgcaagctt tccattgcaa ctttatctgt atctgactca cgaatcgttg aaataatttc
    27781 atcgatatgg tcaagtgcga tacgtaatcc ttctaaaatg tgggcacgat ctttagcttt
    27841 acgtaagttg tattgcgtac gtcttctaac aactgtcttt tgatgctcta aataatgtac
    27901 caacgcttct tttaaattaa taagcttcgg tctaccattt acaagtgcaa tcatattcac
    27961 accaaatgat gtttgaagag gtgtttgttt gtataagtta tttaaaatga cactagcatt
    28021 tgcatcctta cgcacatcaa taacgacacg cacaccagta cgtaaacttg tttcatcacg
    28081 taaatcagtg ataccgtcaa ttttcttgtc acgaacgagc tctgcaattt tttcaatcat
    28141 acgagcctta ttcacttgga aaggaatttc agtgacaaca atacgttgac gtccgcctcc
    28201 acgttcttca ataactgcac gagaacgcat ttgaattgaa ccacgacctg tttcatatgc
    28261 acgtctaata ccactcttac ctaaaataag tccagcagtt gggaaatcag gaccttcaat
    28321 atcctccatt aactcagcaa ttgaaatatc agggttttta cttaagctaa gtacaccatt
    28381 gattaattct gttaagttat gtggtggaat attcgttgcc atacctaccg cgatacctga
    28441 tgcaccattg gctaacaagt tagggaatcg agcaggtaag actgacggct ctctttcatt
    28501 accatcatag ttatcgataa aatctattgt atctttatta atatctcgta acagttcaag
    28561 tgtgatttta gtcatacgtg cttcagtata acgcattgct gctgcgccat ctccatccat
    28621 tgaaccaaag ttaccttggc catcaacaag cggataacga taactgaaat cttgagccat
    28681 acgtaccatt gcttcataaa tagataagtc accatgaggg tgatatttac ccattacgtc
    28741 accaacgata cgtgctgatt ttttatatga tttatccggt gtcatacctt gttcatttaa
    28801 tccatatagt atacgacgat gtactggttt taaaccgtca cgaacatctg gcaatgcacg
    28861 agcaacgata acactcatcg cataatctaa aaatgattca cgcatttcac tggtaatatt
    28921 tcgttcattt attcttgatt gaggtaattc agccatcaag agttcctcct tcaaaagttc
    28981 agttcacagc gcttagaagt ctaagtttgc ataaactgca ttatcttcta taaattgtct
    29041 acggttttct acaacatcac ccattaacat ttcaaatgtt tggtccgctt caatcgcatc
    29101 ttcaagtttt acttgtaaaa gagcgcggtg ctcagggttc attgttgttt cccataattg
    29161 atctgcattc atttctccaa gacctttgta tcgtgcaata gaccattttg gtgttggatt
    29221 caattcagat ttaagtttat caagttccct atcattgtat acataatact tttgtttacc
    29281 ttgtgtcagt ttatacaacg gtggctgtgc aatatacaca tagcctgctt caattaacgg
    29341 tctcataaat cgatagaaga atgttaataa caatgttcta atatgcgctc catccacatc
    29401 ggcatcagtc ataatgacga ttttgtgata tcttgctttc gctagatcaa agtcgccacc
    29461 gattcctgta ccaaatgctg taatcatttg acgaatttca ttgttattca aaattctatc
    29521 taatcgtgct ttttcaacat ttaatatctt acctcgtaat ggtaaaatcg cctgtgttct
    29581 agagtcacga ccagattttg tagacccccc ggcagagtcc ccttcgacta agaaaatctc
    29641 acattcttca ggacttttac tagagcaatc ggctaattta cctggaagac ttgctacatc
    29701 taacgctgat ttacgacgtg taacttcacg cgcttttttc gcagcaacac gtgcacgtgc
    29761 cgccataata cctttttcaa ccactgtacg tgcgacttgt ggattttcat ataaaaatcg
    29821 ttcaaagtgc tctgagaata atttatctac aacttgacgc acttcagaat tacctaattt
    29881 tgtcttcgtt tgaccttcga attgaggatc accatgtttg atagatataa ttgctgtcat
    29941 gccttcacgt gtatcttcac cagaaagtct atctttttct tctttcataa tcttgctact
    30001 taaaccataa ctatttaaga cacgcgttaa tgcacgtttg aatccgtctt catgcgtacc
    30061 accttcgtac gtatgaatgt tatttgcgta agttaaaaga tttgtggcat atcctgagtt
    30121 atattgaatc gcaatttcta cttcaatatc atctttagat tgatgaatat aaattggctc
    30181 atcatgaata ggttctttat tttcgttcaa taactcaaca taagatttaa taccgccctc
    30241 ataatgatag gagtcttctc taacgttttc ttcatcacgt tcatctctta atgtgatttg
    30301 aattcctttg tttaagaaag caagctctct aatacgttgc tgtaatgttt catagttgta
    30361 gacagttgtc tctgtgaaga tttctccatc tgctttaaaa cgaatgacag tacctgtctt
    30421 atcagttgtg ccaacttctt ttaagtcaaa ttgaggtaca ccttttttat atgcttgatg
    30481 atatatagtc tcatttctgt gtacatatac ttctaagtct tgtgacaatg cgtttacaac
    30541 tgatgaacca acaccatgta aaccaccaga tactttgtat ccgccaccgc cgaatttacc
    30601 accagcatgt aaaacagtta aaataacttc gacagctgga cgtcccattt tttcttgaat
    30661 atcaactggg ataccacgtc cgttatccgt tactttaatc cagttatctt tttcaataac
    30721 aacttcaatt tgatttgcat aaccagctaa tgcttcatcg atactattat cgacaatttc
    30781 ccacactaaa tggtgcaaac ctctctctga agtcgatcct atatacatac ctggtctttt
    30841 acgtactgct tctaaacctt ctaatacttg tatttgccca gcaccataat tatccgtgtt
    30901 gtttacatct gacaatgcag tcaccatcgc tttctgttac tttataattt caccttgatt
    30961 aatacgatac aatttagcgt tattcatgat ttcatgatca ataccatcta cagatgtcgt
    31021 agtgacaaat gtttgtactt tatgctgaat cgtacttaat aaatgcgttt gacgcgaatc
    31081 atctaattca ctgagtacat cgtctaataa taagatggga tattccccaa cttcgatatt
    31141 cattaactca atttcagcta atttaatgga caaagccgtt gtacgttgct gtccttgaga
    31201 accatatgtt tgagcatcca tgccattcac atcaaaactt atatcatctc gatgtggtcc
    31261 gaataagcta atgcctcgtt ctttttctct ttgcatatta tcgctaagaa tagacataat
    31321 ttcttcaagt cgtgccgctt cattttgagc ataatcaaat ttaagactag gtaaataatt
    31381 tagcgacaac gcttctttat catttgtgat accagcatga atcggtttag ctaacgactc
    31441 tagctcttga ataaaatgtg cacgtttatc agttactttc attgcatatt cagcaaactg
    31501 ctgatttaat acttccaaca ttgttaagtc ctttttttgg cctaattgta actgctttaa
    31561 gtaattattc ttttgcttta aaatacgttg gtattgagct aaatcattta agtaaacagc
    31621 agaaatttgg cccaactcca tatctataaa gcgtcgtctt atttgaggag agccttttac
    31681 aatattcaaa tcttctggcg caaatagaac cacattgagg tgtccaatat attgagttag
    31741 tcgactttgc tctaagtgat tcactttgac ttgtttacct tttttagtta taaacattgt
    31801 taatggcatc gtgccgtgtc tataactaag ctcaccttct attttagcat aatcagcatt
    31861 aaaacgtatg agttccttat cattactcgt tctatgactt tttgctaaag ctaaggtata
    31921 aattgattca agtaaatttg tctttccttg tgcattttct ccaatgagga tattcacgtc
    31981 aggatgacat ttcaacgtaa cctcatcata gttacgataa ttttctaatt ggagtgtatt
    32041 taacttcatt gttcaccttg atgaatgatt aagaaagaac cagcatcttc aggtaattct
    32101 gggatatcta tacgatcttg atgttctaac tttttaccgc gacgtgtttc acgcactcca
    32161 ttaattaata cttcaacgtc ttgcaagaac cattttgctt gaccaccaga ttcaataatc
    32221 ccttctgttt ttagaaattg acctaaatta atgtctcctt ctactacaac ttcttgaacc
    32281 aaaataatca ctccatttct ttgtatgtca ttaatatatt ataccttttt ttgtcacaaa
    32341 tttcatttaa aatagaggta gaaaccgttt acatataaat aattaattct tatttttggg
    32401 caatactgtc attttcaatt ttttaacgct atttaacggc gtttaacttt tatattcaac
    32461 ttgttattga ctattaaaat tttaaattta aagggcatat aagcacactt attaaatttt
    32521 ggatacattt gtcataaatt taattggcgt cttttatttg ctgtttaaaa tgctgtcaaa
    32581 tttattttac atacgcatct agaattattt ttgccaaaaa ataaaggatg acgttttaat
    32641 taatcacgtc atcctttatt tatatttatt tttagtaagt tctgattggt aaaattaatt
    32701 gcgttactga gtcgtcacct tttggtttta gaataaatgg tttcattgta ccgaagaatt
    32761 caacttcaac ctcatcatta tcgattgctt ttaaagcatc catcatatat ttagagttga
    32821 atgaaatttt caggttacca ccttcaacat cgtttgcatc gacttcttct tttacagtac
    32881 caatttctgg tgatgtagaa gacaattcaa caacgtcatc acctgtactt aatttaataa
    32941 cgttattacc accttcacgt gctaataaag atgcacgatc aatcgcatga taaaactccc
    33001 cattgtctat acttaattta atttcatagt tttcagggaa taaacgtgtt gtatcaggat
    33061 aatgtccttc taataatcga gaaataaagt tcacatttcc aactttaaat aaaacttggt
    33121 ttgaagcaaa gaagatatca atgtcttctt cattgtcaga cataatttta tttaattcag
    33181 ctaaagcctt acctggaatg atgacatttt tgttttcaga aacatcttct aactgcaact
    33241 ttcttacagc caagcggtgc gagtcagtcg ctgtgcatat taattcattt tcttgtataa
    33301 gccagttcac accagttagt actgggcgtg tttctgaggt ggacactgca aaattcgttt
    33361 gtgcaattac gtttttaagc acttttaccg acaattgaat tgcgtcatct ctagaaactt
    33421 gaggtaataa aggatattga tctggatcta agccactcaa attaaattca gaatgacctg
    33481 atgtaattaa tgtctggaat tgttcatttg tagataattt aacatcttta ccaggtaatt
    33541 tttttataat atcaacaaag aatcgtccag gaagtactac tgagcctgtt tctgaaatat
    33601 tgacaatatc ttcgccatct acagttttag gaatagtgat ttctattgaa atttcagagt
    33661 ctgaaccagt tagtataact tcatgttctt tcgcatcgat tttgatacca gttaatatag
    33721 gtaatgttgt tcttggtgaa atagctttta atgtgtcatt taattgtgta ataaaataat
    33781 ctcttttaat agtgaattcc atcattaatt aaaactcctt ccagtcgttt atatataatt
    33841 atataggttt taagttctta gtaatagtag taggtgctgt ggattggtgg ataagtctta
    33901 aaaacataga tttggcgaag ttatacacat gttgataact tgtgtatgat gtgtatgact
    33961 tttaaacatt atccacaaaa tgagttttgc tcatcttgcc acattagtat atagaaatgt
    34021 aaaaaatgac agttattatt agtgctgtta tataacagat tacatttccc aaagtttcct
    34081 acttatacat ttcttatttc tttttcaaga ttctctactt cttgtttaaa aataggatct
    34141 tcttttaaat ctttagatat tttttcatga gcatgaatga cggtcgtatg atcacgccca
    34201 ccaaattctt caccaatttt aggtaatgag aaatctgtaa gctctctaga caagtacata
    34261 gctatttgac gcggatatgc aattgacttt gtacgttttt ttgcactgaa atcttcaatt
    34321 ctaacattat agtactggcc tacaattttt tgaatatctt ggatggtaat ctttttagat
    34381 tttggtgctt gaatgatatc ttttaaagct tcagcagtta attcagttgt aattggtttt
    34441 cctaataatt gtgaatatgc aagtaaacgt gttaatgcac cttctaattc acgaatatta
    34501 gattgaattt gatttgctat ataatttaaa gcttctggtg gaatatctaa tttttcttct
    34561 tcaattttct tctgcaaaat tgccattcga gtttcataat ctggtggcgt aatatcaaca
    34621 attagccccc attcaaagcg tgaacgtaat cgatcttcta attgtgcaat ttcctttggt
    34681 ggtcgatcac tcgaaataac tatttgcttg ttattctgat gcaattcatt aaaagtatag
    34741 aaaaattctt cttgtgtttg tactttattt tgtatgaact gaatatcatc gattaataag
    34801 acgtcgatat tacgatatct ttctctgaaa gcttcacctt cgttatcacg tattgattta
    34861 ataaattcat ttgtgaattt ttcacttgat gtgtaaatca ctttggcatc tggattatta
    34921 tctaaaacat gatgaccaat ggcatgcatt aaatgggttt ttcctaaacc aacacctcca
    34981 tagataaata atggattgta cgctttggct ggtgcttcgg ccacagctaa actcgctgca
    35041 tgtggaaagc ggttaccagg tcctattaca aaagtgtcaa atgtgttatg ggcattgaat
    35101 tgctctctac caagcacatg attatcctca gttgtttcag tagaaggttt tgttgtttct
    35161 tttggagtag cagtttcatt attactataa tttgctaatt cttcagtagt aataaagtga
    35221 ggttttactt catagcctac aacatcaaat aagattgctt ggataatttc agcatattgt
    35281 tgatttaacc aatttgcatt aaaaggaata ctcgataata cgatagcttc accatctttg
    35341 atcgtgtaaa gttcagtatc ttttaggaaa gttgagtaac ttacagctga taatttttct
    35401 tgagcaattt caagcacttt ttcccaaatt tctttttccg acataaattt actccatctt
    35461 tcttaaattt ttaagttata cacaaaaata acagccgtgg ataacttcta aacacaccat
    35521 gttaataatt atccacaagt taataacaat cagtggataa ctttatcctg cttattagtt
    35581 atgcacagta tttttatgta aatatcaata aataaatcct tataaaatca tgagttggac
    35641 gacttatcca cacaattata ctttttcagt tctctatatg tcaaatacct gtgaatatgt
    35701 tgctaaaaat agtataactt tgtgtgtaat ttctaattat ccacaattct gaaaactgta
    35761 aatgtgcata agtggataac ttttccttct atagagtatc tgttagtgag tgtatcaaaa
    35821 cagcttggga aataatttat aaagtatgta taagaacttt ataaggtatt caaacattgt
    35881 aaacactcat gcttcggacc aaactcatgg tgatgttatg aaatttgatt gctcgcatcg
    35941 tgtatttcta tctttaatcg ataaaagtaa aaaaattgag cagtagcata aaatgaactt
    36001 gcgttataaa aaggattttg ttatattgta gtagttgctt gaattatgac tagataatca
    36061 atgagctaat acgagaattt taatctaaga aacgcaaaat cttatctatt aaagtgatca
    36121 gagtctgcat aatctggtat attagataac tgtataaaga tggaggtgtt ttgcatggta
    36181 aaacgtactt atcaaccaaa taaacgtaaa catagtaaag ttcatggttt cagaaaacgc
    36241 atgagcacaa aaaatggccg taaagtttta gcgcgccgtc gtcgtaaagg ccgtaaagtt
    36301 ttatctgcat aagatcactg actcatcagt gatctttttt ttcgtttaaa ttaagaataa
    36361 atagaaattt atgttataag ctcaatagaa gtttaaatat agcttcaaat aaaaacgata
    36421 aataagcgag tgatgttatt ggaaaaagct taccgaatta aaaagaatgc agattttcag
    36481 agaatatata aaaaaggtca ttctgtagcc aacagacaat ttgttgtata cacttgtaat
    36541 aataaagaaa tagaccattt tcgcttaggt attagtgttt ctaaaaaact aggtaatgca
    36601 gtgttaagaa acaagattaa aagagcaata cgtgaaaatt tcaaagtaca taagtcgcat
    36661 atattggcca aagatattat tgtaatagca agacagccag ctaaagatat gacgacttta
    36721 caaatacaga atagtcttga gcacgtactt aaaattgcca aagtttttaa taaaaaaatt
    36781 aagtaatgat agggtagggg aaggtaaaca ttaaccactc aacacctccc gaagtcttac
    36841 ctcagacaaa cgtaagactt accttagggt tataataact tactttaaaa tgtattcaca
    36901 tcgttgaagg aggcgagtag caatatggat ttagatacaa ttacgagtat ttcaacacca
    36961 atgggtgaag gggcaattgg aattgttcga ttgtctggac cgcaagccgt tgaaattgca
    37021 gacatattat ataaaggaaa acatctttta aatgatgttc catcacatac gattaattac
    37081 ggtcatatta ttgatccaga gtctaaagaa gtggttgaag aagttatggt gtctgtgtta
    37141 agagcgccaa aaacatttac acgcgaagat attatagaaa ttaattgtca tggtggtata
    37201 ttaacgatta atagagtgct ggaacttact atgacatatg gcgctcgaat ggctgagcca
    37261 ggtgaattta caaaacgagc ctttttaaat ggtcgtattg atttatctca agctgaagca
    37321 gttatggact ttattcgctc gaagacagat agagcttcta aggttgcgat gaatcaaatt
    37381 gaaggtcgtc taagtgactt aatcaaaaaa caacgtcaat ctatattaga gatactcgct
    37441 caagtagaag tgaatattga ttatcctgaa tacgatgatg ttgaagatgc gactactgaa
    37501 tttcttttag agcagtctaa agaaatcaaa caggaaatta atcgtttatt agataccggt
    37561 gcgcagggta aaattatgcg tgaaggttta tctacagtta ttgttggtaa accaaacgta
    37621 ggtaaatcat cgatgttaaa taatttaata caagataata aagcgattgt aactgaggta
    37681 gcaggtacta caagagatgt cttagaagag tacgtcaatg ttcgtggcgt gccattaaga
    37741 ttagttgata ctgctggtat acgcgagaca gaagatatag tagagaagat tggtgttgaa
    37801 cgctctagaa aggctcttag ccaagcagac ttaattttat ttgtattaaa caataacgaa
    37861 gcattgactc aagaagatta cacattatat gaagtggtta aaaatgaaga tgtaatcgta
    37921 attgttaata aaatggattt agagcaaaac atagatatta atgaagttaa agatatgata
    37981 ggtgatacgc cattaattca aacttcaatg ttaaaacaag aaggtattga tgaattagaa
    38041 atacaaattc gagatttgtt ctttggtgga gaagtacaaa atcaggatat gacttatgtt
    38101 tctaattcaa gacatatttc attattaaaa caagcaagac aaacgataca agatgcgatt
    38161 gatgcagcag aatctggtgt gcctatggat atggtacaaa ttgatttaac tagaacttgg
    38221 gaaatattag gagaaattat tggtgagact gcaagtgatg aactcatcga tcagttattc
    38281 agtcaattct gcttaggtaa atagtaattg aaatagacgg aataccgtct taagaaggct
    38341 agtaagatat caaataagga ggtttatatt gtggttcaag aatatgatgt aatcgttata
    38401 ggtgcgggac atgcaggtgt agaagcaggt ttagcatctg caagacgtgg tgctaaaaca
    38461 ttaatgctaa caataaattt agataatatt gcatttatgc catgtaaccc atctgtaggt
    38521 ggaccagcta aaggtatcgt tgttcgtgaa attgatgctt taggtggaca aatggcaaaa
    38581 acaatcgata aaacacacat tcaaatgaga atgttaaata caggtaaagg acctgctgta
    38641 agagcactaa gagcgcaagc agacaaagta ctttatcaac aagaaatgaa acgcgtgatt
    38701 gaagatgaag aaaatttgca tataatgcaa ggtatggtag acgaacttat tatagaagat
    38761 aatgaagtta aaggtgtacg tacaaatatt ggtacagagt atttatctaa agcagtaatt
    38821 attacaacgg gaacattttt acgtggtgaa atcattttag gtaatatgaa gtattcaagt
    38881 ggaccaaatc accaattacc atcaatcaca ttatcagaca atttaagaga acttggtttt
    38941 gatattgttc gttttaaaac aggtacacca ccgcgtgtaa attcaaaaac aattgactat
    39001 tcgaagactg aaatacaacc aggtgacgat gtaggtcgtg cattcagctt tgaaacaaca
    39061 gaatatatat tagatcaatt gccatgttgg ctaacgtata ctaatgctga aacacacaaa
    39121 gttatcgatg ataatttaca tctatctgca atgtattcag ggatgattaa aggaaccggg
    39181 ccacgttatt gcccttcaat tgaagataaa tttgttcgat ttaatgataa gccgcgacat
    39241 caacttttct tagagcctga aggtcgtaat acaaatgaag tatatgtgca aggattatct
    39301 acaagtcttc ctgaacatgt gcaacgtcaa atgttagaga cgataccagg tcttgaaaaa
    39361 gcagatatga tgcgtgccgg ctacgcaatt gaatatgatg cgattgtgcc aacgcagtta
    39421 tggcctacac ttgaaacgaa aatgattaaa aacttataca ctgcaggtca aattaatggt
    39481 acatctggtt atgaagaagc agcaggacaa ggattgatgg caggtattaa cgctgcaggt
    39541 aaagtgttaa acacaggcga aaagatatta agtcgttcag atgcatatat tggtgtctta
    39601 atcgatgatc ttgtaactaa aggtactaat gaaccttatc gtttactaac atcacgtgca
    39661 gaatatcgtt tgttactacg tcatgataat gctgatttga gattgacgga tatgggatat
    39721 gaacttggta tgatttctga agaacgatat gcacgtttta atgaaaaacg tcagcaaatt
    39781 gatgcggaaa ttaagcgttt atcagatatt cgtattaaac caaacgaaca tacgcaagcg
    39841 attattgaac aacatggtgg ttctcgctta aaagatggta ttttagctat cgatttatta
    39901 cgcagacctg aaatgactta cgatataatt ttagaaattt tagaagaaga acatcaattg
    39961 aatgcagatg ttgaagaaca agtagaaata caaacaaaat atgaaggtta tatcaataaa
    40021 tcactacaac aagttgagaa agttaagcgt atggaagaga agaaaattcc agaagactta
    40081 gattatagta agattgatag tttggcgact gaagcgcgag aaaaattatc agaagtaaaa
    40141 cctttaaata ttgcacaagc ttctagaata tcaggggtaa atccagcaga catatctata
    40201 ttattgattt acttagaaca aggtaaactc caaagggtga gtgactaatg actgtagaat
    40261 ggttagcaga acaattaaaa gaacataata ttgaattaac tgagactcaa aaacaacagt
    40321 ttcaaacata ttatcgttta cttgttgaat ggaatgaaaa gatgaatttg acaagtatta
    40381 cagatgaaca cgatgtatat ttgaaacatt tttatgattc cgttgcacct agtttttatt
    40441 ttgattttaa tcagcctata agtatatgtg atgtaggcgc tggagctggt tttccaagta
    40501 ttccgttaaa aataatgttt ccgcagttaa aagtgacgat tgttgattca ttaaataagc
    40561 gtattcaatt tttaaaccat ttagcgtcag aattacaatt acaggatgtc agctttatac
    40621 acgatagagc agaaacattt ggtaagggtg tctacaggga gtcttatgat gttgttactg
    40681 caagagcagt agctagatta tccgtgttaa gtgaattgtg cttaccgcta gttaaaaaag
    40741 gtggacagtt tgttgcatta aaatcttcaa aaggtgaaga agaattagaa gaagcaaaat
    40801 ttgcaattag tgtgttaggt ggtaatgtta cagaaacaca tacctttgaa ttgccagaag
    40861 atgctggaga gcgccagatg ttcattattg ataaaaaaag acagacgccg aaaaagtatc
    40921 caagaaaacc agggacgcct aataagactc ctttacttga aaaataatgc ataatccttt
    40981 acaactaaca taaaaggagc gaatggataa tgaaaaaacc tttttcaaaa ttatttggtt
    41041 tgaaaaacaa agatgacatc attggacata ttgaagaaga tcgcaatagt aatgttgaat
    41101 ccattcaaat tgaacgtatc gttcccaacc gttatcaacc aagacaggtg tttgaaccaa
    41161 ataaaattaa agaacttgct gaatcaatac atgaacatgg tttactacaa cctattgttg
    41221 taagaccgat tgaagaagat atgtttgaaa ttattgctgg agagcgccga tttagagcaa
    41281 tacaatcact aaatttacct caagcagacg ttattattcg tgatatggat gatgaagaga
    41341 cggctgttgt tgcattaatt gagaatattc aaagagaaaa tttgtctgtt gttgaagaag
    41401 cggaagccta taagaaatta ttggaaattg gtgatacaac gcaaagtgaa ttggcaaaaa
    41461 gtttaggtaa aagtcaaagc tttattgcaa ataagttgcg tttattgaag ttggcgccga
    41521 aagtactact tcgcttaaga gaaggtaaaa ttactgaacg ccatgcgaga gcggtattat
    41581 cattgtctga tagcgaacaa gaagcgttga ttgagcaagt cattgcacaa aagctaaatg
    41641 tgaaacagac tgaagataga gtacgccaaa aaacggggcc cgaaaaagtc aaagcacaaa
    41701 accttcgctt tgcacaagat gtcactcaag cacgagatga ggtaggcaaa agtatccaag
    41761 cgattcaaca aacaggacta catgttgagc ataaagacaa agatcatgaa gattattatg
    41821 aaataaaaat tcgaatatat aaacgttagt agtaggatgt cgtatacatg atgactaaca
    41881 cataaaagac aaagctaaga tcataacagc tttgtctttt tttcttgaaa agaaaaccat
    41941 acgctatgcg tatggttcag aaaaggttct accattgtca caaaaaatgc atctctacgt
    42001 gctagaataa atattggtca gccaaccaaa ataatcaaca cgaggagatg ctatttaatg
    42061 tcatctgaca caaacagttt agcacataca aaatggaatt gtaagtatca tattgtcttt
    42121 gcacctaaat acagaagaca a
//
LOCUS       DAPSKH010000016        41741 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPSKH010000016 DAPSKH010000000
VERSION     DAPSKH010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 41741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41741
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.016"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            149..2680
                     /gene="secA"
                     /locus_tag="RPH49_000960"
     CDS             149..2680
                     /gene="secA"
                     /locus_tag="RPH49_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDY5124140.1"
                     /translation="MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKT
                     KQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGD
                     IAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGL
                     NLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSI
                     LIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAE
                     RMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRR
                     FSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYN
                     MTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEY
                     ISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEEL
                     GGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSR
                     LGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSII
                     DEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKG
                     KDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQG
                     IHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFG
                     EAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK"
     gene            2722..2820
                     /locus_tag="RPH49_000961"
     CDS             2722..2820
                     /locus_tag="RPH49_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124141.1"
                     /translation="MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKK"
     gene            2995..4105
                     /gene="prfB"
                     /locus_tag="RPH49_000962"
     CDS             join(2995..3066,3068..4105)
                     /gene="prfB"
                     /locus_tag="RPH49_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014667688.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDY5124142.1"
                     /translation="MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPN
                     FWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEV
                     IYFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGF
                     KVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFAS
                     CDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQN
                     ERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMV
                     KDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD"
     gene            4258..4365
                     /locus_tag="RPH49_000963"
     CDS             4258..4365
                     /locus_tag="RPH49_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124143.1"
                     /translation="MCLLKQHMQCAFSNITYGDFRGIELIVENVLNYMV"
     gene            4513..5352
                     /locus_tag="RPH49_000964"
     CDS             4513..5352
                     /locus_tag="RPH49_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5124144.1"
                     /translation="MKKSLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQ
                     AQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQ
                     TKAVKSPVRKASQAKKVVQQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPT
                     VPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFK
                     VDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYN
                     YIH"
     gene            5526..6176
                     /locus_tag="RPH49_000965"
     CDS             5526..6176
                     /locus_tag="RPH49_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDY5124145.1"
                     /translation="MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYL
                     ATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVET
                     FIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFE
                     IYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE"
     gene            6173..6409
                     /locus_tag="RPH49_000966"
     CDS             6173..6409
                     /locus_tag="RPH49_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbA family protein"
                     /protein_id="HDY5124146.1"
                     /translation="MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEY
                     FHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR"
     gene            6678..8663
                     /gene="uvrB"
                     /locus_tag="RPH49_000967"
     CDS             6678..8663
                     /gene="uvrB"
                     /locus_tag="RPH49_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002473941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDY5124147.1"
                     /translation="MVEHYPFKIHSDFEPQGDQPQAIKEIVEGIKAGKRHQTLLGATG
                     TGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEA
                     YVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLV
                     VSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEF
                     FGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKEL
                     RNENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDD
                     WLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLV
                     YVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERV
                     LVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLR
                     EGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAI
                     DETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKER
                     QKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG"
     gene            8671..11517
                     /gene="uvrA"
                     /locus_tag="RPH49_000968"
     CDS             8671..11517
                     /gene="uvrA"
                     /locus_tag="RPH49_000968"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDY5124148.1"
                     /translation="MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAF
                     DTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVAT
                     VTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHR
                     KGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETR
                     LADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGAC
                     PTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDK
                     PFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEY
                     TREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSE
                     QDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGV
                     LYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGE
                     HGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKG
                     VDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDK
                     IIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEA
                     CKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFF
                     ENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDE
                     PTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIV
                     ATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK"
     gene            12009..12941
                     /locus_tag="RPH49_000969"
     CDS             12009..12941
                     /locus_tag="RPH49_000969"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDY5124149.1"
                     /translation="MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSH
                     YASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKE
                     LNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSET
                     ALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSI
                     LTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVA
                     AMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE"
     gene            12947..13786
                     /locus_tag="RPH49_000970"
     CDS             12947..13786
                     /locus_tag="RPH49_000970"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDY5124150.1"
                     /translation="MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVK
                     AGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPGEIIKIWHGGIAIHGGLIG
                     GFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLH
                     LPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGR
                     FFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTK
                     KVK"
     gene            13794..14279
                     /locus_tag="RPH49_000971"
     CDS             13794..14279
                     /locus_tag="RPH49_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDY5124151.1"
                     /translation="MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMV
                     LKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEF
                     RYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIR
                     R"
     gene            14287..15726
                     /locus_tag="RPH49_000972"
     CDS             14287..15726
                     /locus_tag="RPH49_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDY5124152.1"
                     /translation="MAQKNNNVIPMTFDDAFYRKMANQKFKQREYKRAAEYFEKVLEL
                     SPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKA
                     FLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKD
                     AKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTL
                     LLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKF
                     LSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPL
                     LQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLEKLNNYEKLYLTYLVQGLTLNKLD
                     FIHRGLLTLYHNELFVSENDVMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQP
                     RNVTKNQITTWLGITQYKLNKMIEFLLSI"
     gene            15793..16728
                     /gene="trxB"
                     /locus_tag="RPH49_000973"
     CDS             15793..16728
                     /gene="trxB"
                     /locus_tag="RPH49_000973"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDY5124153.1"
                     /translation="MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMA
                     NTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKEL
                     TAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEG
                     TFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTL
                     TSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAG
                     DVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA"
     gene            17437..18348
                     /gene="rapZ"
                     /locus_tag="RPH49_000974"
     CDS             17437..18348
                     /gene="rapZ"
                     /locus_tag="RPH49_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499344.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDY5124154.1"
                     /translation="MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPP
                     VLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEAS
                     TEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELK
                     ERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDK
                     DVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERL
                     GNYLNEVFEYNVYVHHRDAHIESGEKK"
     gene            18345..19340
                     /locus_tag="RPH49_000975"
     CDS             18345..19340
                     /locus_tag="RPH49_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDY5124155.1"
                     /translation="MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGK
                     IRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITN
                     DFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLE
                     PNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVM
                     TQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKA
                     ELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK"
     gene            19451..20395
                     /gene="whiA"
                     /locus_tag="RPH49_000976"
     CDS             19451..20395
                     /gene="whiA"
                     /locus_tag="RPH49_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDY5124156.1"
                     /translation="MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVI
                     NVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGI
                     LKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGL
                     TKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNS
                     VNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLK
                     ELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL"
     gene            20958..21545
                     /gene="clpP"
                     /locus_tag="RPH49_000977"
     CDS             20958..21545
                     /gene="clpP"
                     /locus_tag="RPH49_000977"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDY5124157.1"
                     /translation="MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSI
                     VSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSF
                     LLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQ
                     SIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK"
     gene            21727..23387
                     /locus_tag="RPH49_000978"
                     /pseudo
     CDS             21727..23387
                     /locus_tag="RPH49_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000675915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
     gene            complement(23596..24498)
                     /locus_tag="RPH49_000979"
     CDS             complement(23596..24498)
                     /locus_tag="RPH49_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDY5124158.1"
                     /translation="MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKIS
                     YVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSR
                     NKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVV
                     IGRFGIILSNEGGALQTMKLPYEYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESA
                     SGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPN
                     KIQALGFQFKYSNLKMALEDLISK"
     gene            25201..25830
                     /locus_tag="RPH49_000980"
     CDS             25201..25830
                     /locus_tag="RPH49_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4887 domain-containing protein"
                     /protein_id="HDY5124159.1"
                     /translation="MSNQNYDYNKNEDGSKKKMSTTAKVVSIATVLLLLGGLVFAIFA
                     YVDHSNKAKERMLNEQKQEQKEKRQKENAEKERKKKQQEEKEQNELDSQANQYQQLPQ
                     QNQYQYVPPQQQAPTKQRPAKEENDDKASKDESKDKDDKASQDKSDDNQKKTDDNKQP
                     AQPKPQPQQPTPKPNNNQQNNQSNQQAKPQAPQQNSQSTTNKQNNANDK"
     gene            26529..27542
                     /locus_tag="RPH49_000981"
     CDS             26529..27542
                     /locus_tag="RPH49_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDY5124160.1"
                     /translation="MKDLLQAQQKLIPDLIDKMYKRFSILTTISKNQPVGRRSLSEHM
                     DMTERVLRSETDMLKKQDLIKVKPTGMEITAEGEQLISQLKGYFDIYADDNRLSEGIK
                     NKFQIKEVHVVPGDADNSQSVKTELGRQAGQLLEGILQEDAIVAVTGGSTMACVSEAI
                     HLLPYNVFFVPARGGLGENVVFQANTIAASMAQQAGGYYTTMYVPDNVSETTYNTLLL
                     EPSVINTLDKIKQANVILHGIGDALKMAHRRQSPEKVIEQLQHHQAVGEAFGYYFDTQ
                     GQIVHKVKTIGLQLEDLESKDFIFAVAGGKSKGEAIKAYLTIAPKNTVLITDEAAAKI
                     ILE"
     gene            27595..28605
                     /gene="gap"
                     /locus_tag="RPH49_000982"
     CDS             27595..28605
                     /gene="gap"
                     /locus_tag="RPH49_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDY5124161.1"
                     /translation="MAVKVAINGFGRIGRLAFRRIQEVEGLEVVAVNDLTDDDMLAHL
                     LKYDTMQGRFTGEVEVVDGGFRVNGKEVKSFSEPDASKLPWKDLNIDVVLECTGFYTD
                     KDKAQAHIEAGAKKVLISAPATGDLKTIVFNTNHQELDGSETVVSGASCTTNSLAPVA
                     KVLNDDFGLVEGLMTTIHAYTGDQNTQDAPHRKGDKRRARAAAENIIPNSTGAAKAIG
                     KVIPEIDGKLDGGAQRVPVATGSLTELTVVLEKQDVTVEQVNEAMKNASNESFGYTED
                     EIVSSDVVGMTYGSLFDATQTRVMSVGDRQLVKVAAWYDNEMSYTAQLVRTLAYLAEL
                     SK"
     gene            28744..29934
                     /locus_tag="RPH49_000983"
     CDS             28744..29934
                     /locus_tag="RPH49_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDY5124162.1"
                     /translation="MAKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTI
                     QYIIEQGGKIVLFSHLGKVKEESDKAKLTLRPVAEDLSKKLDKEVVFVPETRGEKLEA
                     AIKDLKEGDVLLVENTRYEDLDGKKESKNDPELGKYWASLGDVFVNDAFGTAHREHAS
                     NVGISTHLETAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIAD
                     KIIIGGGMAYTFLKAQGKEIGISLLEEDKIDFAKDLLEKHGDKIVLPVDTKVAKEFSN
                     DAKITVVPSDSIPADQEGMDIGPNTVKLFADELEGAHTVVWNGPMGVFEFSNFAQGTI
                     GVCKAIANLKDAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEYLEGKELPGIKA
                     IDNK"
     gene            30056..30817
                     /locus_tag="RPH49_000984"
     CDS             30056..30817
                     /locus_tag="RPH49_000984"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDY5124163.1"
                     /translation="MRTPIIAGNWKMNKTVQEAKDFVNALPTLPDSKEVESVICAPAI
                     QLDALTTAVKEGKAQGLEIGAQNTYFEDNGAFTGETSPVALADLGVKYVVIGHSERRE
                     LFHETDKEINKKAHAIFKHGMTPIICVGETDEERESGKANDVVGEQVKKAVAGLSENQ
                     LKSVVIAYEPIWAIGTGKSSTSEDANEMCAFVRQTIADLSSKEVSEATRIQYGGSVKP
                     NNIKEYMAQTDIDGALVGGASLKVEDFVQLLEGAK"
     gene            30820..32337
                     /locus_tag="RPH49_000985"
     CDS             30820..32337
                     /locus_tag="RPH49_000985"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDY5124164.1"
                     /translation="MAKKPTALIILDGFANRESEHGNAVKLANKPNFDRYYNKYPTTQ
                     IEASGLDVGLPEGQMGNSEVGHMNIGAGRIVYQSLTRINKSIEDGDFFENDVLNNAIA
                     HVNSHDSALHIFGLLSDGGVHSHYKHLFALLELAKKQGVEKVYVHAFLDGRDVDQKSA
                     LKYIEETEAKFNELGIGQFASVSGRYYAMDRDKRWEREEKAYNAIRNFDAPTYATAKE
                     GVEASYNEGLTDEFVVPFIVENQNDGVNDGDAVIFYNFRPDRAAQLSEIFANRAFEGF
                     KVEQVKDLFYATFTKYNDNIDAAIVFEKVDLNNTIGEIAQNNNLTQLRIAETEKYPHV
                     TYFMSGGRNEEFKGERRRLIDSPKVATYDLKPEMSAYEVKDALLEELNKGDLDLIILN
                     FANPDMVGHSGMLEPTIKAIEAVDECLGEVVDKILDMDGYAIITADHGNSDQVLTDDD
                     QPMTTHTTNPVPVIVTKEGVTLRETGRLGDLAPTLLDLLNVEQPEDMTGESLIKH"
     gene            32467..33771
                     /gene="eno"
                     /locus_tag="RPH49_000986"
     CDS             32467..33771
                     /gene="eno"
                     /locus_tag="RPH49_000986"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017466665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDY5124165.1"
                     /translation="MPIITDVYAREVLDSRGNPTVEVEVLTESGAFGRALVPSGASTG
                     EHEAVELRDGDKSRYLGKGVTKAVENVNEIIAPEIIEGEFSVLDQVSIDKMMIALDGT
                     PNKGKLGANAILGVSIAVARAAADLLGQPLYKYLGGFNGKQLPVPMMNIVNGGSHSDA
                     PIAFQEFMILPVGATTFKESLRWGTEIFHNLKSILSKRGLETAVGDEGGFAPKFEGTE
                     DAVETIIQAIEAAGYKPGEEVFLGFDCASSEFYENGVYDYSKFEGEHGAKRTAAEQVD
                     YLEQLVDKYPIITIEDGMDENDWDGWKQLTERIGDRVQLVGDDLFVTNTEILAKGIEN
                     GIGNSILIKVNQIGTLTETFDAIEMAQKAGYTAVVSHRSGETEDTTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDELFETAKYDGIKSFYNLDK"
     gene            34122..34580
                     /locus_tag="RPH49_000987"
     CDS             34122..34580
                     /locus_tag="RPH49_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124166.1"
                     /translation="MADRTNKEIKTGRFIATASIVFSILLIIHYFVSLDNATAKALLN
                     LTNQNTSDKAIDYILNSFRFTGIMYILAYLAGFITFWNRHTYVWWFMFAVYVSNSLFT
                     LINLSITIQAIKAAHGAYLTLPILIVIIGSVALAIYMLVVSIKRKSTFNR"
     gene            34647..34880
                     /gene="secG"
                     /locus_tag="RPH49_000988"
     CDS             34647..34880
                     /gene="secG"
                     /locus_tag="RPH49_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDY5124167.1"
                     /translation="MHTFLIVLLIIDCIALITVVLLQEGKSSGLSGAISGGAEQLFGK
                     QKQRGVDLFLNRLTIILSILFFVLMICISYLGM"
     gene            34996..35736
                     /locus_tag="RPH49_000989"
     CDS             34996..35736
                     /locus_tag="RPH49_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HDY5124168.1"
                     /translation="MQIKLPKPFFFEEGKRAVLLLHGFTGNSSDVRQLGRFLQKKGYT
                     SYAPQYEGHAAPPEEILQSSPFVWFKDALDGYDYLVEQGYDEIVVAGLSLGGDFALKL
                     SLNRDVKGIVTMCAPMGGKTEGAIYEGFLEYARNFKKYEGKDQETIDNEMHHFKPTET
                     LKELSEALGTIKDQVDEVFDPILVIQAENDNMIDPQSANYIYEHVDSDDKNIKWYSES
                     GHVITIDKEKEQVFEDIYQFLESLDWSE"
     gene            35770..38142
                     /gene="rnr"
                     /locus_tag="RPH49_000990"
     CDS             35770..38142
                     /gene="rnr"
                     /locus_tag="RPH49_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDY5124169.1"
                     /translation="MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLV
                     ELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPT
                     KINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDD
                     KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSI
                     IYQHGIEIEFPDEVLQEAEAVPDHIENTEIKGRHDLRDELTITIDGADAKDLDDAISV
                     KKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRVIPMIPHRLSNGICS
                     LNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPAIREQY
                     NEITPMLDLAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEDGIPTDVQLRQRGEGERL
                     IESFMLIANETVAEHFSKLDVPFIYRVHEQPKSDRLRQFFDFITNFGIMIKGTGEDIH
                     PTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFTSPIRRY
                     PDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAE
                     YMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQ
                     AKVFRIGDTIKVKVTHVDVDERLIDFQIVGMPLPKNDRSQRPARGKTIQAKTRGKSLD
                     KSKSDDKGHKKKGKQRKGKNERKNDKSGNSKHKPFYKDKSVKKKARRKKK"
     gene            38164..38628
                     /gene="smpB"
                     /locus_tag="RPH49_000991"
     CDS             38164..38628
                     /gene="smpB"
                     /locus_tag="RPH49_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDY5124170.1"
                     /translation="MAKKKSPGTLAENRKARHDYNIEDTIEAGIVLQGTEIKSIRRGS
                     ANLKDSYAQVKNGEMYLNNMHIAPYEEGNRFNHDPLRSRKLLLHKREIIKLGDQTREI
                     GYSIVPLKLYLKHGHCKVLLGVARGKKKYDKRQALKEKAVKRDVARDMKARY"
     gene            38719..39080
                     /gene="ssrA"
                     /locus_tag="RPH49_000992"
     tmRNA           38719..39080
                     /gene="ssrA"
                     /locus_tag="RPH49_000992"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(39191..40297)
                     /locus_tag="RPH49_000993"
     CDS             complement(39191..40297)
                     /locus_tag="RPH49_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015728767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDY5124171.1"
                     /translation="MTHNLNLSHNIYKDTKRGTYYFRITYYDKSNTRKYITRKGFKQR
                     KDAVKKCNEMMDELEGVGHLNRLSFDKLVEEYIDWYSARRKTSSVKALKTHTNNHLLP
                     YFKSMDVFKMTTQDVMKFQNKKLKEGHSGDYLKKMHVYLVSLLNHAMKFHELKQNVAS
                     LVGNFEIESQKRLNYWTLEQFNQFYGALVTQQQKLFFKLLFYSGARKGEIRALTWRDI
                     NFDDDFIHINKTDYHGEVTAPKTKSAIRDIYLPTHMMDDIKGYLNWYKENNIFKDDYV
                     LFGTFYKAYSESTIDRWFTNALKVLDEQLPNGQNFPRIVIHELRHSHASMLVNLGASV
                     MIIAQRLGHSDTTEVYNRYGHLYPSTQKEIVKYL"
     gene            complement(40287..41090)
                     /locus_tag="RPH49_000994"
     CDS             complement(40287..41090)
                     /locus_tag="RPH49_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5124172.1"
                     /translation="MDKKTDIGLRIKSIRLAKGLNLREFGEEISKLTKEKKYISDSIV
                     SRWEKGVSIPNAKRLKAIAEYGNVSINFLLYGNEISYEDIYQNIKSVNMKNNIQDKLI
                     DFIVNYMPSSEQNTYYFKVASLITIINDHTDSNIDCIIEQMYSFISNENMTFYHHGVY
                     LLLNEDFKKLPVQLYLTEFIYHLLIQISLKYPEVYFLNLLSQFDDLKSNIQEISTKHE
                     ILHNHTRRSKIAEFIDSKEYQKLMNKIDVMKEKLLNKNILKKQGDTHDT"
     gene            41226..41429
                     /locus_tag="RPH49_000995"
     CDS             41226..41429
                     /locus_tag="RPH49_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDY5124173.1"
                     /translation="MNKVLGYRKMLNFTQQQMAKELKISEQSYRNKEKGKTEFKKEEM
                     LTFKNILISKGMTNITLDDIFFN"
     gene            41465..41683
                     /locus_tag="RPH49_000996"
     CDS             41465..41683
                     /locus_tag="RPH49_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5124174.1"
                     /translation="MTKLAYPMLYITRKEKGDTQKKVASKLGISPQRYQLKESGKAIF
                     NLNECQILSEMYDMPIDELFSSKIKVGE"
BASE COUNT        14973 a         5963 c         8015 g        12790 t
ORIGIN      
        1 cttgttgtca acagaatgtg aatgaagtat gtcataaata tatttatatt gattctacaa
       61 atgagtaaat aagtataatt ttctaactat aaatgataag atatattgtt gtaggccaaa
      121 cagtttttta gctaaaggag cgaacgaaat gggattttta tcaaaaattc ttgatggcaa
      181 taataaagaa attaaacagt taggtaaact tgctgataaa gtaatcgctt tagaagaaaa
      241 aacggcaatt ttaactgatg aagaaattcg taataaaacg aaacaattcc aaacagaatt
      301 agctgacatt gataatgtca aaaagcaaaa tgattattta gataaaattt taccagaagc
      361 atatgcactt gttagagaag gctctaaacg tgtattcaat atgacaccat ataaagttca
      421 aattatgggt ggtattgcaa ttcataaagg tgatatcgct gagatgagaa caggtgaagg
      481 taaaacgtta acagcgacaa tgccaacata cttaaatgca ttagctggta gaggtgttca
      541 cgttattaca gtcaatgaat atttatcaag tgttcaaagt gaagaaatgg ctgagttata
      601 taacttctta ggtttgactg tcggattaaa cttaaacagt aagacgactg aagaaaaacg
      661 tgaagcatat gcgcaagaca ttacttacag tactaacaat gagttaggtt ttgactattt
      721 aagagataac atggtgaatt attctgaaga tagagtaatg cgtccattac atttcgcaat
      781 cattgatgag gttgactcaa ttttaattga tgaggcacgt acgccattaa ttatttctgg
      841 tgaagctgaa aagtcaacgt cactttatac acaagcaaat gtttttgcga aaatgttaaa
      901 gcaggacgaa gattataaat atgatgaaaa aacaaaagca gtacatttaa cagaacaagg
      961 tgcggataaa gctgaacgta tgttcaaagt tgaaaactta tatgatgtac aaaatgttga
     1021 tgttattagt catatcaaca cagctttacg tgcgcacgtt acattgcaac gtgacgtaga
     1081 ctatatggtt gttgatggcg aagtattaat tgtcgaccaa tttacaggac gtacaatgcc
     1141 aggccgtcgt ttctcggaag gtttacacca agctattgaa gcgaaggaag gcgttcaaat
     1201 tcaaaatgaa tctaaaacta tggcgtctat tacattccaa aactatttca gaatgtacaa
     1261 taaacttgcg ggtatgacag gtacagctaa aactgaagaa gaagaattta gaaatattta
     1321 taacatgaca gtaactcaaa ttccgacaaa taaacctgtg caacgtaacg ataagtctga
     1381 tttaatttac attagccaaa aaggtaaatt tgatgcagta gtagaagatg ttgttgaaaa
     1441 acacaaggca gggcaaccag tgctattagg tactgttgca gttgagactt ctgaatatat
     1501 ttcaaattta ctaaaaaaac gtggtatccg tcatgatgtg ttaaatgcga aaaatcatga
     1561 acgtgaagct gaaattgttg caggcgctgg acaaaaaggt gccgttacta ttgccactaa
     1621 catggctggt cgtggtacag atatcaaatt aggtgaaggc gtagaggaat taggcggttt
     1681 agcagtaata ggtacagaac gacatgaatc tcgtcgtatt gatgaccagt tacgtggtcg
     1741 ttctggacgt caaggtgata aaggggatag tcgcttctat ttatcattac aagatgaatt
     1801 aatgattcgt tttggttctg aacgtttaca gaaaatgatg agccgactag gtttagatga
     1861 ctctacacca attgaatcaa aaatggtatc aagagctgta gaatcagcac aaaaacgtgt
     1921 agaaggtaat aacttcgacg cgcgtaaacg tatcttagaa tacgatgaag tattacgtaa
     1981 acaacgtgaa attatctata acgaaagaaa tagtattatt gatgaagaag acagctctca
     2041 agttgtagat gcaatgctac gttcaacgtt acaacgtagt atcaattact atattaatac
     2101 agcagatgac gagcctgaat atcaaccatt catcgactac atcaatgaca ttttcttaca
     2161 agaaggtgac attacagagg atgatatcaa aggtaaagat gctgaagata ttttcgaagt
     2221 cgtttgggct aagattgaag cagcatatca aagtcaaaaa gatatcttag aagaacaaat
     2281 gaatgagttt gagcgtatga ttttacttcg ttctattgat agccattgga ctgatcatat
     2341 cgacacaatg gatcaattac gtcaaggtat tcacttacgt tcttatgcac agcaaaatcc
     2401 attacgtgac tatcaaaatg aaggtcatga attatttgat atcatgatgc aaaatatcga
     2461 agaagatact tgtaaattca ttttaaaatc tgtagtacaa gttgaagaca atattgaacg
     2521 tgaaaaaaca acagagtttg gtgaagcgaa gcacgtttca gctgaagatg gtaaagaaaa
     2581 agtgaaaccg aaaccaatcg ttaaaggcga tcaagttggt cgtaacgatg attgtccatg
     2641 tggtagtggt aaaaaattca aaaattgcca tggaaaataa atgatataaa ataactcctt
     2701 ccaattaaac acctatagtt tgtgttatgg gaggagtctt tttattttac aagcgttaaa
     2761 tactttaaaa aatgtgaaga agttgttaaa cgttgttatg tacttagttt taaaaaatag
     2821 gtttaggcat atatcgatga taaatgtact gatttttaac aataaaagca taaactgatt
     2881 gtcagtgtgc ttatatttct taacattgtt atttaacaaa attatgttaa aatttagcat
     2941 tataaatgat acaaatcaat gacttgaatt gaattataaa taggagcgaa ggctatggaa
     3001 ttatcagaaa tcaaacgaaa tatagataag tataatcaag atttaacaca aattaggggg
     3061 tctctttgac ttagagaaca aagaaactaa tattcaagaa tatgaagaaa tgatggcaga
     3121 acctaatttt tgggataacc aaacgaaagc gcaagatatt atagataaaa ataatgcgtt
     3181 aaaagcaata gttaatggtt ataaaacact acaagcagaa gtagatgaca tggatgctac
     3241 ttgggattta ttacaagaag aatttgatga agaaatgaaa gaagacttag agcaagaggt
     3301 catttatttt aaggctaaag tggatgaata cgaattgcaa ttattattag atgggcctca
     3361 cgatgccaat aatgcaattc tagagttaca tcctggtgca ggtggcacgg agtctcaaga
     3421 ttgggctaat atgctattta gaatgtatca acgttattgt gagaagaaag gttttaaagt
     3481 tgaaactgtt gattatttac ctggagatga agcagggatt aaaagtgtaa cattgctcat
     3541 caaagggcat aatgcttatg gttatttaaa agctgaaaaa ggtgtacacc gactagtacg
     3601 aatttctcca tttgattcat caggacgtcg tcatacatca tttgcatcat gtgacgtgat
     3661 tccagatttt aataatgatg aaatagagat tgaaatcaat ccggatgata ttacagttga
     3721 tacattcaga gcttctggtg caggtggtca gcatattaac aaaactgaat cggcaatacg
     3781 aattacccac cacccctcag gtatagttgt taataaccaa aatgaacgtt ctcaaattaa
     3841 aaaccgtgaa gcagctatga aaatgttaaa gtctaaatta tatcaattaa aattggaaga
     3901 gcaggcacgt gaaatggctg aaattcgtgg cgaacaaaaa gaaatcggat ggggaagcca
     3961 aattagatca tatgttttcc atccatactc aatggtgaaa gatcatcgta cgaacgaaga
     4021 aacaggtaag gttgatgcag tgatggatgg agatattgga ccatttatcg aatcatattt
     4081 aagacagaca atgtcacacg attaatatat attttaaaac cgaggctcta aaagggcgtc
     4141 ggtttttggt tttttatagg tagctaaata aattgtaaat tagattttgg aatatgattt
     4201 gtttatgaat atttaagtac aattgggtag atagggttag aatatatttt ttaaaagttg
     4261 tgtttgttaa aacaacatat gcagtgtgca tttagtaata ttacctatgg cgattttcga
     4321 ggtattgaat taatcgttga aaacgttctc aattacatgg tatgaataca ttttacacta
     4381 tgataaaagg ttgtattctt tttatattgt taaccatttg attacatcgt tataacaata
     4441 gcttttgaca aaatgtattg tgctatagta tttgcatact taaaattcta acagcaaagg
     4501 aatgacagca agatgaaaaa atctcttaca gtgacggttt cgtcagtgtt agctttttta
     4561 gctttaaata atgcagcaca tgcacaacaa catggcacac aagtaaaaac acctgttcaa
     4621 cataattatg tatcaaatgt tcaagcacaa acgcaatcac cgacaactta tacagtagtt
     4681 gctggcgatt cattatataa gattgcatta gagcatcact taacgttgaa tcaattatat
     4741 tcatacaatc ctggtgtaac acctttaatt tttcctggtg acgtgatttc acttgtgcct
     4801 caaaataaag tgaaacaaac taaagcggtt aaatcaccag taagaaaagc aagccaagct
     4861 aaaaaggtag tacaacaacc tgtacaacaa gcgtctaaaa aagtagtagt taagcaagca
     4921 cctaagcaag cagtagctaa gacagttaat gtagcataca aacctgctca agtacaaaaa
     4981 tcagttccaa ctgtacctgt tgcacataac tacaataaat cagttgctaa cagaggaaac
     5041 ttatatgctt atggaaactg cacatattat gctttcgatc gtcgtgcaca attaggtaga
     5101 agtataggaa gtttatgggg caatgcaaat aactggaatt acgcagcaaa agttgcagga
     5161 tttaaagtag ataaaacacc agaagttggc gctattttcc aaacagctgc tggcccatat
     5221 ggacatgttg gtgttgttga atctgtaaac cctaatggaa caattactgt ttctgaaatg
     5281 aactatgctg gatttaatgt taaatcttca agaacaattt taaatccagg aaaatataat
     5341 tacatccact aagtaatata tcaagacaag actatcctct tagcctgttt aagtaacagg
     5401 ttgagaggat tttttggtat catttaatca gagttatata aagaagatat ttaaatgata
     5461 tttaattgat tgatatgtaa aaagaaagta taatttatga ttaattaatg gaggaggtaa
     5521 ttgaaatggg tgtacatcaa tattttaaaa gattatcaga tatggaaaga cttataagat
     5581 tacctggaaa atttaaatat tttgaacaca atgttgcagc acactccttt aaagtaacta
     5641 aaattgctca atatctagca acagttgaag aatatcatgg acgaaagatt aattggaaaa
     5701 gcttatatga aaaagcatta aatcatgatt tcgctgaagt gtttactggt gatataaaaa
     5761 cacctgttaa atatgcgagt agtgaattaa aaaaattatt ttcgcaagtt gaagaagaaa
     5821 tggtagagac ctttattgaa gaagaaattc cattacaata tagagatgtt tataagcaac
     5881 gactgcaaga aggtaaagat gattcattag aaggccaaat actttcagtt gctgataaaa
     5941 ttgatttgct ttatgaaaca tttggagaaa tacaaaaacg taatcctgaa gaattatttt
     6001 tcgaaattta tgaaatgagt ctagaaacaa ttattcaatt cgaccattta gcatctgtac
     6061 aagattttat taataatatc attccagaaa tgttgactga aaactttata cctagaacag
     6121 aattaagaga aacaaccatg aacattttaa ataaaagaaa agaggaaaat gaatgatatg
     6181 gtattttagc gcagcattct ttccatgtgt cttggtagta ttatttagtg taataacaag
     6241 aagtaaatgg gtcggtacta ttctgacatt aattttaatt ggtgcctcaa tctataaaga
     6301 gtatttccat aacgagtgga ttatttttat tgatgtagtg tcattattag ctggttattt
     6361 aattatagat caactcgaat ttcataaaca tcaagatgaa gatcgctaag attaacttta
     6421 aaataatgtt tcaaacaaat ttgttgaaac aaaatgatga ttaatataat gtgtatttac
     6481 atactaaaaa taacaagata aacgatttga tttaaggcaa gcatagttag cacaactatg
     6541 tttgtttttc tttgttcgat atttttacga acaaacgttt gctttttgtg tgactacttt
     6601 gctaaaatat gtaatgagaa agcgaagagt tgagcggaaa tataaataat acgttgaaag
     6661 aggaggtata tgtgacaatg gttgaacatt atccttttaa aatacattct gattttgagc
     6721 ctcaaggtga ccaaccgcaa gcaattaagg aaatcgtgga aggtattaaa gcggggaaaa
     6781 gacatcaaac tttattaggt gcaactggca cagggaaaac atttacgatg agtaatgtta
     6841 ttaaagaagt tgggaaacca acgttaatta tcgcgcataa caaaacatta gcaggacaat
     6901 tatatagtga gtttaaagaa ttttttcctg aaaacagggt ggaatacttt gtaagttact
     6961 atgattatta tcaacctgag gcatacgtac cgtctactga cacttttatt gaaaaagatg
     7021 cctcaatcaa tgatgaaatt gatcaactac gacattctgc tacaagtgca ttatttgaac
     7081 gcgatgatgt aattattatt gctagtgtaa gttgtatata tggtttaggt aatcctgaag
     7141 aatataaaga tttagtagta agtgttcgag ttggtatgga aatggataga agtgaattac
     7201 ttagaaaact tgtagatgtg caatatacac gaaatgacat cgatttccaa cgaggaacgt
     7261 ttcgagtgcg tggtgatgta gttgaaatat tcccagcctc taaagaagaa ctttgtataa
     7321 gggttgagtt tttcggcgat gagattgacc gtatccgaga agttaactac ctaacaggtg
     7381 aagtgttgaa agaaagagaa cattttgcga tattcccagc ttctcacttc gtaacacgtg
     7441 aagaaaagtt gaaagttgcg attgaacgta ttgaaaaaga attggaagaa cgattgaaag
     7501 aattacgaaa tgagaataaa ttactagaag cgcaaaggtt agaacagcgt accaactatg
     7561 atttagaaat gatgcgagag atgggattct gttcaggaat tgaaaactat tccgtacatt
     7621 taactttgcg accactgggt tcgacaccat atactttatt ggattacttt ggcgatgatt
     7681 ggttagtaat gattgatgaa tcacatgtga cattaccgca agttcgaggc atgtataacg
     7741 gagacagagc gcgtaaacaa gttttggtgg atcatggatt tagattaccg agtgcattag
     7801 ataaccgtcc tcttaaattt gaagaatttg aagaaaagac aaaacaactt gtgtatgtat
     7861 ctgcaacgcc tggaccatac gaaattgaac atacggataa gatggttgaa caaattattc
     7921 gtcctactgg tttactggat cctaagattg aggttagacc tactgaaaat caaattgacg
     7981 atttattaag tgaaattcaa acaagggttg aacgtaatga acgcgtactt gttacaacgc
     8041 tcactaaaaa gatgagtgaa gatttaacca catacatgaa agaagcgggt attaaagtta
     8101 attatctgca ttcagaaatc aagacattag aacgaatcga aataattaga gacttacgaa
     8161 tgggtacata tgatgttatc gtaggtatta atttattaag agagggtatt gatataccag
     8221 aagtttctct agttgtcata ttagatgcag ataaagaagg atttttacgt tctaaccgct
     8281 ctttaattca aacaataggt agagctgcgc gtaacgataa aggtgaagtc attatgtatg
     8341 ccgataaaat gactgattcg atgaagtatg caattgatga gacacaacgt cgtcgagaaa
     8401 tacagatgaa acataatgaa aaacatggta ttacacctaa aacaattaat aaaaaaatac
     8461 atgatttaat tagtgctact gttgaaaatg acgaaaataa tgacaaagca caaactgtga
     8521 tacctaagaa gatgacgaaa aaagaacgtc aaaagacaat cgacaatata gaaaaagaaa
     8581 tgaaacaagc agcgaaagat ttagatttcg agaaagctac agaattaaga gatatgttat
     8641 ttgaattaaa agcagaaggg tgacaagtaa atgaaagaac catccatagt agtaaaaggt
     8701 gctcgtgcgc ataacttgaa agatattgat atcgaactac ctaaaaataa attaattgtt
     8761 atgacaggat tatctgggtc aggtaaatcg tcattagcat tcgatactat atatgctgaa
     8821 ggacaacgac gttatgttga atcattaagt gcctatgcgc gtcaattttt aggccaaatg
     8881 gacaaaccag atgttgatac aatcgaagga ttatcgccag caatttcaat agatcaaaaa
     8941 acaacaagta aaaatccaag atcaactgtt gcaacagtaa cagaaatata tgattatata
     9001 cgtttgttat atgcacgtgt tggtaaacct tactgtccaa atcacaatat agaaattgaa
     9061 tcacaaacag tacaacaaat ggttgaccgc attatggagt tagaggcacg tacaaagatt
     9121 caattattag cacctgtcat cgctcatcgt aaaggtagtc atgaaaagct aatcgaagat
     9181 attggtaaaa aaggttatgt acgtttaaga atcgatggcg aaattgttga tgtaaatgat
     9241 gtacctacat tagataagaa caagaatcat acaatagaag ttgttgtaga ccgattagtt
     9301 gttaaagatg gaattgaaac acgactagct gactctatag aaactgcgtt agagctttca
     9361 gaaggacaat taacagttga tgtcattgac ggggaagacc ttaagttttc agaaagccat
     9421 gcttgtccta tatgtggatt ttcaatcgga gaattagaac caagaatgtt tagctttaat
     9481 agtccttttg gtgcttgtcc aacatgtgat ggcttaggcc aaaagttaac agtcgatgta
     9541 gacttggttg ttccagacaa agataagacg ctaaacgaag gtgcaataga accttggata
     9601 ccgacgagtt ctgattttta tccaacattg ttaaaacgtg tttgtgaagt ttataaaatc
     9661 aatatggata aaccttttaa aaagttaaca gaacgtcaac gtgatatttt attgtatggt
     9721 tcgggtgaca aagaaattga atttacattt acacaacgtc aaggtggtac tagaaaacga
     9781 acaatggttt tcgagggtgt agttcctaat ataagtagac gattccatga atctccttca
     9841 gaatatacac gtgaaatgat gagtaaatat atgactgaac taccttgtga aacttgtcat
     9901 ggaaagcgat tgagtcgtga agcgttatct gtttatgtag gtggtttaaa tattggtgaa
     9961 gtagtcgaat actcaatcag tcaagcgctg aactattata aaaacattga tttgtcagaa
    10021 caagatcaag cgattgcaaa tcaaatattg aaagaaatta tttcccgact cactttttta
    10081 aataatgtcg gacttgaata tttaacgcta aacagagctt caggtacact ttcaggtggt
    10141 gaagcacaac gtattcgatt ggcaacgcaa attgggtcgc gtttgactgg tgtcttatat
    10201 gtattagatg agccatcaat tggactgcat caaagagata atgatcgatt aattaataca
    10261 cttaaagaaa tgagagattt aggaaatact ttaattgtag ttgaacacga tgatgataca
    10321 atgcgtgcgg ctgattactt agtggatata gggcctggtg ctggtgaaca tggaggacaa
    10381 attgtgtcta gtgggacacc tcaaaaggta atgaaagata aaaaatcttt aacaggacaa
    10441 tacttgagtg gtaagaaacg tattgacgta cctgaatatc gcagaccggc ttcagatcgt
    10501 aaaatttcta tacgtggagc tagaagtaac aaccttaaag gcgttgatgt ggacatacca
    10561 ctatcaatca tgacggtcgt tacaggtgta tcaggttctg gtaaaagctc attagtaaat
    10621 gaagtattat acaaatcatt agctcaaaaa atcaataaat ctaaagtaaa gccaggattg
    10681 tacgataaga ttgaaggtat tgatcaactt gataaaatta ttgatattga tcaatcaccg
    10741 ataggtagaa cgccacgctc taatccagca acatatactg gtgtgtttga tgatatacgt
    10801 gatgtgtttg cgcaaacaaa tgaagctaaa atccgaggat atcaaaaagg gcgttttagt
    10861 tttaatgtaa aaggtggacg ctgtgaagct tgtaaaggtg acggtattat taaaattgaa
    10921 atgcattttt tacctgatgt ttatgttcct tgtgaagtgt gtgatggtaa acgatataat
    10981 cgtgagacac tagaggttac ttacaaaggt aaaaatattg ctgacatttt agaaatgact
    11041 gttgaagaag caacacaatt ttttgaaaat attcctaaga ttaagcgcaa gttacaaaca
    11101 ctagttgatg ttggtcttgg atacgtcaca ttaggtcaac aagctacaac gttatcaggt
    11161 ggtgaggctc aacgtgtgaa acttgcatct gaacttcata aacgttcaac tggtaaatct
    11221 atttatatcc tagacgaacc aacaacaggg ttacatgttg acgatattag cagattatta
    11281 aaagtattaa accgattagt tgaaaatggt gatactgttg taattattga acataaccta
    11341 gatgttatca aaacagcaga ctatattatc gacttaggtc ctgaaggtgg tagtggcggt
    11401 ggtactattg ttgcgactgg cacacccgaa gatattgctc agacaaagtc atcctataca
    11461 ggaaagtatt taaaagaagt acttgaacga gataaacaaa atactgaaga taaataagat
    11521 taaaagaagt gaaggatgtt gtaaatttat ccttcacttc tttttattaa tttagtaatg
    11581 aatagtagaa agaaaagaag cgtaaaaaga attatgttaa gatagggtca atctagagtt
    11641 gctaaacata aatcgaactg ggagtgggac agaaatgata ttttcgcaaa atttatttcg
    11701 tcgtcccacc ccaactagca ttgtctgtag aaattgggaa tccaatttct ctgtgttggg
    11761 gccccgccaa ctaattccaa tatatcattt tagagtttag gtcattgatt tatggcttgg
    11821 acttttatgt cgatatgaac catgtaaatt aagcattcaa taaattaatg attgatattg
    11881 acttgtaaaa taataacaat aatgaacaat taatatttat tttagctttt caatgtagat
    11941 tggtgttata tttttgatat gataagaaga gatgtaagag tagggataaa tacaattgag
    12001 gtgaacccat gttaacgaca gaaaaactag ttgaaacatt aaagttagat ttaatcgctg
    12061 gtgaagaagg actatcgaag ccaattaaaa atgctgatat atcaagaccg ggcttagaga
    12121 tggcaggtta tttttcacat tatgcgtcag atagaataca actattagga acaacggaac
    12181 tatcgtttta caatttatta ccagataagg atcgcgcagg tcgtatgcgt aaactatgca
    12241 gaccagaaac gcctgcaatt attgtgacac gtggattgca gccaccagaa gaattagttg
    12301 aagctgcaaa agaattaaat acgccactta tagttgctaa agatgcaact acaagtttaa
    12361 tgagtcgatt aacaacgttt ttagagcatg cacttgcaaa gacgacatct ttacatggtg
    12421 ttttagtgga tgtttacggt gtaggcgtat taattaccgg tgattctggt attggtaaaa
    12481 gtgagactgc gttagaatta gtgaagcgtg ggcatagact agtagcagat gataatgtag
    12541 aaatacgtca aattaataaa gatgaactaa tagggaaacc accaaagtta atagaacatc
    12601 tattagaaat acgtggacta ggtattatca atgttatgac tttatttggc gcgggttcaa
    12661 tattaactga aaaacgaatt agattaaata ttaatttgga aaactggaac aagcaaaagt
    12721 tatatgaccg cgtaggtctt aatgaagaga cgttaagtat tttagatact gaaataacta
    12781 aaaaaacaat acctgtaaga cctggtagaa atgttgcggt aattattgag gtcgctgcaa
    12841 tgaactatcg attaaatatc atgggcatta acactgccga agaatttagt gaaagattaa
    12901 atgaagaaat tatcaagaac agtcataaga gtgaggagta ggttgaatgg gtattgtatt
    12961 taactatata gatcctgtgg catttaactt aggaccactg agtgtacgat ggtatggaat
    13021 tatcattgct gtcggaatac tacttggtta ctttgttgca caacgtgcac tagttaaagc
    13081 aggattacat aaagatactt tagtagatat tattttttat agtgcactat ttggatttat
    13141 cgcggcacga atctatttcg tgattttcca atggccatat tacgcggaaa atccaggtga
    13201 aattattaaa atatggcatg gtggtatagc aatacatggt ggtttaatag gtggctttat
    13261 tgctggtgtt attgtatgta aagtgaaaaa tttaaaccca tttcaaattg gtgatatcgt
    13321 tgcgccaagt ataattttag cgcaaggaat tggacgctgg ggtaacttta tgaatcacga
    13381 ggcacatggt ggacctgtgt cacgcgcttt tttagaacaa ttacatttgc ctaattttat
    13441 aatagaaaat atgtatatca acggccaata ttatcatcca acattcttat atgaatccat
    13501 ttgggatgtc gctggattta ttatcttagt taatattcgt aaacatttaa aattaggaga
    13561 aacattcttt ttatatttaa cttggtattc aattggtcga ttctttatag aaggattacg
    13621 tacagatagc ttaatgctca caagtaatat tagagttgca caattagtat caattctttt
    13681 aattttaata agtataagtt taattgtata tagaaggatt aagtataatc caccgttgta
    13741 tagcaaagtt ggggcgcttc catggccaac aaaaaaagtg aagtagtgat attttgagaa
    13801 aatttttatc aaaaacacat catcatacaa accctttatg gcgtgtatac cgtcttgtta
    13861 aattttcgaa agtttttaag aatgtaatta tcattgaatt ttcgaaattt attccaagta
    13921 tggtactgaa aagacatata tataaacaac ttttaaatat taatatcggt aatcaatcgt
    13981 cgatagctta caaagtaatg ttagatattt tttacccaga actgattacg attggtagta
    14041 acagtgttat tggttacaat gtaacaattt tgacgcatga agcattagtt gatgaatttc
    14101 gttatggacc agtgacgata ggatctaaca ctttgattgg tgcaaatgct accattttac
    14161 ccggtataac gattggtgac aatgtaaaag ttgcagctgg tacggttgtt tcaaaagata
    14221 taccggataa tggatttgca tatggcaacc ctatgtatat aaaaatgatt aggaggtgac
    14281 aattttatgg cgcaaaagaa taataacgta attccaatga cttttgatga tgcattttat
    14341 cgtaaaatgg ctaatcagaa gtttaaacaa agagaatata aacgagctgc tgaatacttt
    14401 gaaaaagtgt tagaattgtc acctgatgat ctggaaattc aaattgatta tgcacaatgt
    14461 ctagtgcaac ttggtattgc taaaaaagca gaacatttat tttatgacaa tattatttat
    14521 aataggcatc tagaagatag cttttatgaa ttgagtcagc tcaacattga agttaacgaa
    14581 ccaaacaagg cattcttgtt tggtattaat tatgttattg ttagcgacga ccaagattat
    14641 agagatgaat tagatcaaat gtttgatgtg aaatatcaaa gtgaagaaca aattgaactt
    14701 gaagctcaat tgtttgtagt tcaaatacta ttccaatatc ttttttctca aggtcgatta
    14761 aaagatgcaa agaattatgt cttacatcaa ccacaagaag ttcaagatca tcgtgtcgta
    14821 cgtaatttat tggcaatgtg ttatttatat ctcggcgaat atgacacggc taaagcattg
    14881 tacgaagcac tattacaaga ggatagtaca gatatatatg cattatgcca ttatactttg
    14941 ctactttata acactaagga aaatgaacaa taccaaaaat atttaaaaat attaaataaa
    15001 gttgtaccta tgaatgacga tgaaagtttt aaattaggta ttgttttaag ttatttaaag
    15061 cagtatcgtg catcacaaca attgttgtac cctttatata aaaaagggaa atttttatca
    15121 attcaaatgt acaatgcttt agcatataat tattattatt taggtgaaga agacgaaagt
    15181 cattactact gggataaatt gaagcaaatt tctaaagtgg aaattggaca tgcgccttgg
    15241 gtaattgaaa atagcaaaga agttttcgac caacatattt tgccattact tcaaagtgat
    15301 gacagtcatt atcgtttata tggtattttt ttattggatc aattaaatgg taaagaaatt
    15361 gtgatgacgg aaagtatttg gcaggttctg gaaaaactaa ataattatga gaaattgtat
    15421 ttaacgtatt tagttcaagg tttaacgctc aataaattag acttcattca tcgcggcttg
    15481 ttaacgcttt accataatga attatttgtg agtgaaaatg atgtaatggt tgcatggatt
    15541 aatcaaggtg aactcataat tgctgaaaaa gtagatttaa ctgatgttga gccatatatc
    15601 ggtgcgttta tttatttgta ttttaaaaat caacctcgaa atgttacaaa gaaccaaatt
    15661 acaacatggt taggcataac acaatataaa ctgaacaaaa tgattgaatt tctcttgagc
    15721 atatagattt atgaaaagtt agatttatta tataatgcgc ataatgatta ataatgagga
    15781 ggcgttaata aaatgactga aatagatttt gatatagcaa ttatcggtgc aggtccagct
    15841 ggtatgactg ctgcagtata cgcatcacgt gctaatttaa aaacagttat gattgaaaga
    15901 ggtattccag gcggtcaaat ggctaataca gaagaagtag agaacttccc tggtttcgaa
    15961 atgattacag gtccagattt atctacaaaa atgtttgaac acgctaaaaa gtttggtgca
    16021 gtttatcaat atggagatat taaatctgta gaagataaag gcgaatataa agtgattaac
    16081 tttggtaaca aagaattaac agctaaagcg gtcattattg ctacaggtgc agaatacaag
    16141 aaaattggtg ttccgggtga acaagaactt ggtggacgcg gtgtaagtta ttgtgcagta
    16201 tgtgatggtg cattctttaa aaataaacgc ctattcgtta tcggtggtgg tgactcagca
    16261 gtagaagagg gaacattctt aactaaattt gctgacaaag taacaattgt tcaccgtcgt
    16321 gatgagttac gtgcacaacg tattttacaa gatagagcat tcaaaaatga taaaatcgac
    16381 tttatttgga gtcatacttt gaaatcaatt aatgaaaaag acggcaaagt gggttctgtg
    16441 acattaacgt ctacaaaaga tggttcagaa gaaacacacg aggctgatgg tgtattcatc
    16501 tatattggta tgaaaccatt aacagcgcca tttaaagact taggtattac aaatgatgtt
    16561 ggttatattg taacaaaaga tgatatgaca acatcagtac caggtatttt tgcagcagga
    16621 gatgttcgcg acaaaggttt acgccaaatt gtcactgcta ctggcgatgg tagtattgca
    16681 gcgcaaagtg cagcggaata tattgaacat ttaaacgatc aagcttaatt cgaagtcgaa
    16741 ttaagatgtt gagttgtaaa ttatttagat atttatttta atagtgtcat cacattgtta
    16801 aaataatgtc ttacttttaa attaaagcaa attatataga aaactagaac ttagtacgta
    16861 tcatttgtgc gtttcaatga gttctagttt ttttatatgt tatattaaac ttataacttt
    16921 atgggagtag gacagaaatg ataaagagcc actaatgatt tattatgtag tggttcttac
    16981 acattagccc agctaatgtg tacttaaaaa taggaataca tgagtaaaac tcatgcataa
    17041 gaaatactaa tttctataga aaaagtattt ctttatcgtt gtcccacccc aactcgcatt
    17101 gcctgtagaa tttcttttcg aaattctctg tgttggggcc cacaccccaa cttgcattgt
    17161 ctgtagaaat tggaaatcca atttctctgt gttggggccc ctgactagag ttgaaaaaag
    17221 cttgttgcaa gcgcgttttc attcagtcaa ctactagcaa tataatatta tagaccctag
    17281 gacattgatt tatgtcccaa tctcctttta aatgatgtat atttttagaa atttaatcta
    17341 ggcatagtta aaaataaata taaaacatcg ttgcttaatt ttgtcataga acatttaaat
    17401 taacatcatg aaattcgttt tggcggtgaa aaaataatgg ataataatga aaaagaaaaa
    17461 agtaaaagtg aactattagt tgtaacaggt ttatctggcg caggtaaatc tttggttatt
    17521 caatgtttag aagacatggg atatttttgt gtagataatc taccaccagt gttattgcct
    17581 aaatttgtag agttgatgga acaaggaaat ccatccttaa gaaaagtggc aattgcaatt
    17641 gatttaagag gtaaggaact atttaattca ttagttgcag tagtggataa agttaaaagt
    17701 gaaagtgacg tcatcattga tgttatgttt ttagaagcaa gtactgaaaa attaatttca
    17761 agatataagg aaacgcgtcg tgcacatcct ttgatggaac aaggtaaaag atccttaatc
    17821 aatgcaatta atgatgagcg agagcatttg tctcaaatta gaagtatagc taattttgtt
    17881 atagatacta caaagttatc acctaaagaa ttaaaagaac gcattcgtcg atactatgaa
    17941 gatgaagagt ttgaaacttt tacaattaat gtcacaagtt tcggttttaa acatggaatt
    18001 cagatggatg cagatttagt atttgatgta cgatttttac caaatccata ttatgtagta
    18061 gatttaagac ctttaacagg attagataaa gacgtttata attatgttat gaaatggaaa
    18121 gagacggaga ttttctttga aaaattaact gatttgttag attttatgat acctgggtat
    18181 aaaaaagaag ggaaatctca attagtaatt gccatcggtt gtacgggtgg acaacatcga
    18241 tctgtagcat tagcagaacg actaggtaat tatctaaatg aagtatttga atataatgtt
    18301 tatgtgcatc atagggacgc acatattgaa agtggcgaga aaaaatgaga caaataaaag
    18361 ttgtacttat cggtggtggc actggcttat cagttatggc taggggatta agagaattcc
    18421 caattgatat tacggcgatt gtaacagttg ctgataatgg tgggagtaca gggaaaatca
    18481 gagatgaaat ggatatacca gcaccaggag acatcagaaa tgtgattgca gctttaagtg
    18541 attctgagtc agttttaagc caactttttc agtatcgctt tgaagaaaat caaattagcg
    18601 gtcactcatt aggtaattta ttaatcgcag gtatgactaa tattacgaat gatttcggac
    18661 atgccattaa agcattaagt aaaattttaa atattaaagg tagagtcatt ccatctacaa
    18721 atacaagtgt gcaattaaat gctgttatgg aagatggaga aattgttttt ggagaaacaa
    18781 atattcctaa aaaacataaa aaaattgatc gtgtgttttt agaacctaac gatgtgcaac
    18841 caatggaaga agcaatcgat gctttaaggg aagcagattt aatcgttctt ggaccagggt
    18901 cattatatac gagcgttatt tctaacttat gtgtcaatgg tatttcagat gcgttaattc
    18961 attctgatgc gcctaagcta tatgtttcta atgtgatgac gcaacctggg gaaacagatg
    19021 gttatagcgt gaaagatcat atcgatgcga ttcatagaca agctggacaa ccgtttattg
    19081 attatgtcat ttgtagtaca caaactttca atgctcaagt tttgaaaaaa tatgaagaaa
    19141 aacattctaa accagttgaa gttaataagg ctgaacttga aaaagaaagc ataaatgtaa
    19201 aaacatcttc aaatttagtt gaaatttctg aaaatcattt agtaagacat aatactaaag
    19261 tgttatcgac aatgatttat gatatagctt tagaattaat tagtactatt cctttcgtac
    19321 caagtgataa acgtaaataa tatagaacgt aatcatatta tgatatgata atagagctgt
    19381 gtaaaaaaat gaaaatagac agtggttcta aggtgaatca tgttttaaat aagaaaggaa
    19441 tgactgtacg atgagctttg catcagaaat gaaaaatgaa ttaactagaa tagacgtcga
    19501 tgaaatgaat gcaaaagcag agctcagtgc actgattcga atgaatggtg cacttagtct
    19561 ttcaaatcaa caatttgtta taaatgttca aacggaaaat gcaacaacgg caagacgtat
    19621 ttattcgttg attaaacgtg tctttaatgt ggaagttgaa atattagtcc gtaaaaaaat
    19681 gaagcttaaa aaaaataata tttatatttg tcgtacaaag atgaaagcga aagaaattct
    19741 tgatgaatta ggaattttaa aagacggcat ttttacgcat gaaattgatc attcaatgat
    19801 tcaagatgat gaaatgagac gcagttactt gagaggagct tttctggcag gtggctcagt
    19861 gaataaccct gaaacatctt cgtaccattt ggaaattttt tctcaaaatg agagtcatgc
    19921 agaaggctta acgaaactaa tgaatagtta tgagttgaat gccaaacatt tagagcgaaa
    19981 aaaaggaagt attacgtatt taaaagaagc ggaaaagatt tcggattttc ttagtttgat
    20041 aggtggctat caagcgttat taaaatttga agacgtacgt attgtaagag atatgcgtaa
    20101 ttctgttaac cgactcgtta attgtgaaac ggcaaatcta aataaaacag ttagtgctgc
    20161 gatgaaacaa gttgagagca ttaaattgat tgataaagaa attggtattg aaaatttacc
    20221 agacaggttg agagagattg ctagaattcg agtagaacat caagaaattt cgttgaaaga
    20281 gcttggagaa atggtatcaa ctggtccaat ttcaaaatca ggtgtaaatc accgattaag
    20341 aaaacttaat gatttagccg ataagattag aaatggtgaa caaatagaat tataagtaag
    20401 aaggtgtttt tggtagtgaa ttatcaaaaa cactttttta tgattaaaaa gtgtttaatg
    20461 aataatagtc gactaactat taaattgagc tggaaagttt aatgaaggaa attcaataac
    20521 caagtgatgc ctaattttct cattaaatag catcatatgt atcaatttgg tcataagaaa
    20581 atatgaatgt gataattaat tgagtccctg atcatagaca aaaacaaaat cagcataaat
    20641 aagaatcccg acattgcggg attctcagta ttgaaaagta ttgtatttta ttaaaacagc
    20701 ctccttgaag ggaattgaac ccctatctta agaaccggaa tcttacgtgt tatccattac
    20761 accacaagga gcaaatatgt aatcatatct ctgtactatg agaagtaaaa taagtacaat
    20821 ctaaaataga tattatcagt ttacaaagga aagagaaaag cgtcaaacaa tgtaactatt
    20881 taaagtcaaa gtgtttgacc aaatttgact taatatgtaa aataatgagt aacagttatt
    20941 acaaggagga aatatagatg aatttaattc ctacagttat tgaaacaaca aaccgcggtg
    21001 aacgtgcata tgatatatac tcacgtttat taaaagaccg tattattatg ttaggttcac
    21061 aaattgatga caacgtagca aattcaatcg tatcacagtt attattctta caagcgcaag
    21121 actcagagaa agatatttat ttatacatta attcaccagg tggaagtgta acagctggtt
    21181 ttgcgattta tgatacaatt caacacatta aacctgatgt tcaaacaatt tgtatcggta
    21241 tggctgcatc aatgggatca ttcttattag cagctggtgc aaaaggtaaa cgtttcgcgt
    21301 taccaaatgc agaagtaatg attcaccaac cattaggtgg tgctcaagga caagcaactg
    21361 aaatcgaaat tgctgcaaat cacattttaa aaacacgtga aaaattaaac cgcattttat
    21421 cagagcgtac tggtcaaagt attgaaaaaa tacaaaaaga cacagatcgt gataacttct
    21481 taactgcaga agaagctaaa gaatatggct taattgatga agtgatggta cctgaaacaa
    21541 aataattcaa agtaaagagt agactaagca gtctgctctt tttgtatgag taaaccaagg
    21601 tatcaataaa ttgtttaaaa tattttgagt aaaagcaaaa aataacgggt aaaaatattt
    21661 gtgagaattt aattagacac gttgtttctg cggttctaca atctaacaaa tataaaggat
    21721 gattttatga aaggcattga attacttaac aatccatttt taaacaaagg tacagctttt
    21781 actaacgaag aaagaaaaca gttagggctt gaaggtttat tacctgcgaa tgttcgaact
    21841 ttagaacaac aagcagaaca atgttatgaa caattcaagg cgaaacaaac cgattttgag
    21901 aaacgtttat ttttaatggc aatttttaat cgtaatcgta cattgtttta caaattgact
    21961 tcaaagcatt tagttgaatt tatgccaatt atttatgacc ctgttattgc tcaatcgatt
    22021 gaacaatata atgagaactt cagcagaccc caagatgcag tatttttatc tgttgataga
    22081 caagaccaaa ttgaacaaga attgcgcaac gttgcaaatg gcagagatat tcgattaatt
    22141 gtagtgacag atgcggaagg tatattaggt atcggcgatt ggggtgttga tggtgtagat
    22201 attgcgatag gaaaattaat agtatataca gcagcagctg gaataaatcc ttcacaagta
    22261 ctacctgtat ctttagatgt aggtactaat aatgaacaat tactataggt actaataatg
    22321 aacaattact aaaggatgac ctttatttag gaaatcgtca taaacgtgtc gatgatgaga
    22381 catattacgc atttgtagat aaatttgtga gtgcagtgcg taaagaatat cctaatgcac
    22441 tattacattg ggaagatttt ggtagagggc atgccaaaaa tattttagat aaatatgaag
    22501 atacgttacc aacttttaat gatgatattc aaggtacagg tatagttaca ttagctggcg
    22561 tactaggtgc attaaatatt tctaaagtag attatacgaa tcagacgttt ttagtttatg
    22621 gtggtggtac agctggtatg ggtattacca atattttaaa agatgaacta attaaacagg
    22681 gtgtttcaga agaaaaagca aatcagcatt tcttcattat ggataaacag ggattgttgt
    22741 ttgatgatat ggatgattta actgaagcgc aacaagtatt tgctaaaaat aggaatgaat
    22801 tttcaaatac agtaaactgg aaaaatttaa aagaagtaat tgaaaatatt aagcctactg
    22861 ttttaatcgg tacatcaact cagacaggtg catttacaga agatgcagta aaagagatgt
    22921 taaaacatac agaacgtcca atgattttcc cattgtctaa tcctacaaaa ttagcagaag
    22981 caactgcaca agatttatta aaatggacta acggaaaagc attaattgga actggtatcc
    23041 catataatga cattgaatac aatggtgtga attacagtat tggtcaagca aataatgcat
    23101 tgatgtatcc tggtttaggt ttgggactta ttgcgtcaaa agcgaagaaa gtaaatcaac
    23161 agattctatc agctgcgagt catgcacttg gtggcatggt caatccagat gaaccaggtg
    23221 ctgcagtctt accacctgtc gagaaaatac atcaatgttc tcgtgccata gccaaagcgg
    23281 ttgcacaaag tgtcattgat caaggattaa acgctgaaac tattgatgat attgacaaag
    23341 caattgaagc tgaaatttgg tatcctgaat acaaatcata catttaattt tataaagtag
    23401 taaaaggtca tttgaatatt ttgtttcaag tggccttttc gtatttactt taaaattaat
    23461 caaccaatat tcataagtga ctttaaagtt atatctatat gtaatatcag caaatagaaa
    23521 agtctagaga gatttaacga attatctcct agactttttg cttgaagtgg agtaggagag
    23581 agatcaatgt cccactcact tactaattaa atcttcaagt gccattttta aattactata
    23641 tttaaattgg aatcccaatg cttgaatttt attaggtaat actttttgag tatccaatac
    23701 tactgttgac atttgaccaa gtatgagacg cattgcaaga cttggtgccc aagtttcatg
    23761 aggcttatgc atagctcttg ctaaagtgta gccaaataaa ttttgacgct caggtatagg
    23821 tgcagttaaa ttaaacggac cactagctga ctcgttattt attaaaaata aaatagcttg
    23881 aattaaatca ttgatatgaa tccatgaata ccattgttga ccagaaccta atttaccacc
    23941 aatgtaatat tcgtatggca gtttcattgt ttgtaacgca ccgccttcat tcgataaaat
    24001 tataccgaaa cgaccgatga caactcgtgt acctaattgt tcaaattgtt gtgcgaaacg
    24061 ttcccattga tacacaatat ctgataagaa atcaaaaggt aaagttttat aaacttctgt
    24121 gtaactcata aataaatcag gaggatagta accagtggca ctagcattaa ataaaacttt
    24181 aggtgcttta ttacgtgatt taaacaattc atataaagct tgcgtagatt gaattctact
    24241 tagcattagc gtttgtttat attccggtgt ccatcgttta ttcaatgtag cacctgctaa
    24301 gttgatgacc acatcgatat tttgaggaac tttgtgttcc cacccagatt tagcccagtt
    24361 gacatatgaa attttcttat catttgaaat ttggtcgtgt cgcgttaata tcgtgatatg
    24421 tgaatctgat tttttaattt cattaactaa ttgagatcca accataccag tcccaccagt
    24481 aattaagtat tgtttcatta tcattcaccc catgtaattt tgtatttagt tactatttaa
    24541 taatcattat tgttgttcaa aggttataca ttatttagac aataatatgt caataacttt
    24601 ttttgaattg tattttaata aaaatgatat aagttataat aaaggtgtac cttcgataac
    24661 gaataaacat ctcttaaaag tatgtgtaaa acgctgcatg atacaaacga aggtaaaaat
    24721 ttgactccct ttagtagtgg acccgtacgt ttatcgtgcg ggtcgttttt atttatttct
    24781 tattcccatt atacatcaat ttaaagcatt aattttttaa acaaatttaa gaatacatag
    24841 taatataaca atctaaacat aaaaactttt aacccaacgc ttaaactaat gctttaattt
    24901 tcaatacgta gctataattt gttgtaaaat caaaaaggtt aatatgttaa ttttcaaaaa
    24961 aaggctcaaa atatgtttga tttagttatt aaatgttaag atatataaga ctactatttc
    25021 tttgtaaaaa tgaatccgat ttacgagtga gtaatagtga aggcagtttt aagttgaaga
    25081 aggcaaaaag agtaaatgtt tattaatatt tgtagaaact aggtaaacaa attagttgtg
    25141 aaaatgttaa tggttgcgtg ataatttcta tatttaaatt agtttgaagt gagggagagt
    25201 atgtcgaatc aaaattacga ctacaataaa aatgaagatg gaagtaagaa gaaaatgagt
    25261 acaacagcga aagtagttag cattgcgacg gtattgctat tactcggagg attagtattt
    25321 gcaatttttg catatgtaga tcattcgaat aaagctaaag aacgtatgtt gaacgaacaa
    25381 aagcaggaac aaaaagaaaa gcgtcaaaaa gaaaatgcag aaaaagagag aaagaaaaag
    25441 caacaagagg aaaaagagca gaatgagcta gattcacaag caaaccaata tcagcaattg
    25501 ccacagcaga atcaatatca atatgtgcca cctcagcaac aagcacctac aaagcaacgt
    25561 cctgctaaag aagagaatga tgataaagca tcaaaggatg agtcgaaaga taaggatgac
    25621 aaagcatctc aagataaatc agatgataat cagaagaaaa ctgatgataa taaacaacca
    25681 gctcagccta aaccacagcc gcaacaacca acaccaaagc caaataataa tcaacaaaac
    25741 aatcaatcaa atcaacaagc aaaaccacaa gcaccacaac aaaatagcca atcaacaaca
    25801 aataaacaaa ataatgctaa tgataagtag tatttagtca aacaaaaatg aaccagtatg
    25861 acagacaaca caattaatta ggttgtctcg aatattggtt cttattttta taattgttaa
    25921 ttaggggaga gatgatactt aaatagttag ttgtttattt tgaagatagt gaaatttatt
    25981 ttgagtgagg tgggacagaa atgatatttt cgcaaaattt atttcgtcgt cccaccccaa
    26041 cttccattgc ctgtagaaat tggaaatcca atttctctat gttggggccc accccaactt
    26101 gcacattatt gtaagctgac tttccgccag cttctatgtt ggggcccctg actttaattg
    26161 aaaaatgctt gttacaagtg cattttcgtt cggtcaacta ctactaatgt aactttttgg
    26221 attctagagc attgatttat gtcttagttc aaataataag caaatgatta gcgagtcagt
    26281 ataagggtat acatttgact acagcgaata aaataaaacg ttttgttgaa taacaaatcg
    26341 aaaatgtatt gcaagcgctt tatcaaatta tttagaaaat ttaagtttta tgcttgcaat
    26401 ttttgaaata gaatagtact attgcaagtg taaagaggtt aatttttgtc ccacgcggga
    26461 cttaaaaagg caaccactgg ttgtgacata tccttattta catttataaa tataaggagg
    26521 aggtagtagt gaaagactta ttgcaagcac agcaaaagct tataccggat ctcatagata
    26581 aaatgtataa acgtttttct attcttacta ctatctcaaa aaatcagcct gtcggacgtc
    26641 gaagtttaag cgaacatatg gatatgactg aacgtgtact gcgttctgaa acagatatgc
    26701 ttaagaaaca agatttgata aaagttaagc ctaccggaat ggaaattaca gctgaaggtg
    26761 agcaactgat ttcgcaattg aaaggttact ttgatatcta tgcagatgat aatcgtctgt
    26821 cagaaggtat taagaataaa tttcaaatta aggaagttca tgttgttcct ggtgatgctg
    26881 ataatagtca atctgttaaa acagaattag gtagacaagc aggtcaatta cttgaaggca
    26941 tattacaaga agacgcgata gttgctgtaa ctggcggatc cacgatggca tgtgttagtg
    27001 aagcaattca tttattacca tataatgtat tcttcgtacc agccagaggt ggactaggcg
    27061 aaaatgttgt ctttcaggca aacacaattg cagccagtat ggcacaacaa gctggcggtt
    27121 attatacgac gatgtatgta cctgataatg tcagtgaaac aacatataac acattgttgt
    27181 tagagccatc agtcataaac actttagaca aaattaaaca agcaaacgtt atattacacg
    27241 gcattggtga tgcgctgaag atggcgcatc gacgtcaatc acctgaaaag gtcattgaac
    27301 aacttcaaca tcatcaagct gtcggagagg catttggtta ttattttgat acacaaggtc
    27361 aaattgtcca taaggttaaa acaattggac ttcaattaga agaccttgaa tcaaaagact
    27421 ttatttttgc agttgcagga ggcaaatcga aaggtgaagc aattaaagca tacttgacga
    27481 ttgcacccaa gaatacagtg ttaatcactg atgaagccgc agcaaagata atacttgaat
    27541 aagagataaa aagtttaata ctttttaaat atcattttaa aggaggccat tataatggca
    27601 gtaaaagtag caattaatgg ttttggtaga attggtcgtt tagcattcag aagaattcaa
    27661 gaagtagaag gtcttgaagt tgtagcagta aacgacttaa cagatgacga catgttagcg
    27721 catttattaa aatatgacac tatgcaaggt cgtttcacag gtgaagtaga ggtagttgat
    27781 ggtggtttcc gcgtaaatgg taaagaagtt aaatcattca gtgaaccaga tgcaagcaaa
    27841 ttaccttgga aagacttaaa tatcgatgta gtattagaat gtactggttt ctacactgat
    27901 aaagataaag cacaagctca tattgaagca ggcgctaaaa aagtattaat ctcagcacca
    27961 gctactggtg acttaaaaac aatcgtattc aacactaacc accaagagtt agacggttct
    28021 gaaacagttg tttcaggtgc ttcatgtact acaaactcat tagcaccagt tgctaaagtt
    28081 ttaaacgatg actttggttt agttgaaggt ttaatgacta caattcacgc ttacacaggt
    28141 gatcaaaata cacaagacgc acctcacaga aaaggtgaca aacgtcgtgc tcgtgcagcg
    28201 gcagaaaaca tcatccctaa ctcaacaggt gctgctaaag ctatcggtaa agttattcct
    28261 gaaatcgatg gtaaattaga tggtggtgca caacgtgttc ctgtagctac aggttcatta
    28321 actgaattaa cagtagtatt agaaaaacaa gacgtaacag ttgaacaagt taacgaagct
    28381 atgaaaaatg cttcaaacga atcattcggt tacactgaag acgaaatcgt ttcttcagac
    28441 gttgtaggta tgacttacgg ttcattattc gacgctacac aaactcgtgt aatgtcagtt
    28501 ggcgaccgtc aattagttaa agttgcagct tggtatgata acgaaatgtc atatactgca
    28561 caattagttc gtacattagc atacttagct gaactttcta aataatttta gtatagtttt
    28621 tattcaaata cgctagtgct cagaactatt tagcattaat taaagcttat gagtaagcgg
    28681 ggagcacaaa cgcttctccg cttattttta tataaaattt cctaattaca aggaggaaac
    28741 accatggcta aaaaaattgt ttctgattta gatcttaaag gtaaaacagt cctagtacgt
    28801 gctgatttta acgtaccttt aaaagacggt gaaattacta atgacaaccg tatcgttcaa
    28861 gctttaccta caattcaata catcatcgaa caaggtggta aaatcgtact attttcacat
    28921 ttaggtaaag taaaagaaga aagtgataaa gcaaaattaa ctttacgccc agttgctgaa
    28981 gacttatcta agaaattaga taaagaagtt gttttcgtac cagaaacacg cggcgaaaaa
    29041 cttgaagctg ctattaaaga ccttaaagaa ggcgacgtat tattagttga aaatacacgt
    29101 tatgaagatt tagacggtaa aaaagaatct aaaaatgatc cagaattagg taaatactgg
    29161 gcatctttag gtgatgtgtt tgtaaatgat gcttttggta ctgcgcatcg tgagcatgca
    29221 tctaatgttg gtatttctac acatttagaa actgcagctg gattcttaat ggataaagaa
    29281 attaagttta tcggtggcgt agttaacgat ccacataaac cagttgttgc tattttaggt
    29341 ggagcaaaag tatctgacaa aattaatgtc atcaaaaact tagttaacat agctgataaa
    29401 attatcatcg gcggaggtat ggcttatact ttcttaaaag cgcaaggtaa agaaattggt
    29461 atttcattat tagaagaaga taaaatcgac ttcgcaaaag atttattaga aaaacatggt
    29521 gataaaattg tattaccagt agacactaaa gttgctaaag aattttctaa tgatgccaaa
    29581 attactgtag taccatctga ttcaattcca gcagaccaag aaggtatgga tattggacca
    29641 aacactgtaa aattatttgc agatgaatta gaaggtgcgc acactgttgt atggaatgga
    29701 cctatgggtg tattcgagtt cagtaacttt gcacaaggta caattggtgt atgtaaagca
    29761 attgcaaacc ttaaagatgc aattacgatt atcggtggcg gtgattcagc tgcagcagca
    29821 atctctttag gttttgaaaa tgacttcact catatttcaa ctggtggcgg tgcgtcatta
    29881 gagtacctag aaggtaaaga attgcctggt atcaaagcaa tcgataataa ataataaagt
    29941 gatagtttaa agtgatgtgg catgtttgtt taacattgtt acgggaaaac agtcacaaga
    30001 tgacatcgtg tttcatcact tttcaaaaat atttacaaaa caaggagtgt ctttaatgag
    30061 aacaccaatt atagctggta actggaaaat gaacaaaaca gtacaagaag caaaagactt
    30121 cgtcaatgca ttgccaacat taccagattc aaaagaagta gaatcagtaa tttgtgcacc
    30181 agcaattcaa ttagatgcat taactactgc agttaaagaa ggaaaagcac aaggtttaga
    30241 aatcggtgct caaaatacgt atttcgaaga taatggtgcg ttcacaggtg aaacgtctcc
    30301 agttgcatta gcagatttag gcgttaaata cgttgttatc ggtcattctg aacgtcgtga
    30361 attattccac gaaacagata aagaaattaa caaaaaagcg cacgctattt tcaaacatgg
    30421 aatgactcca attatatgtg ttggtgaaac agacgaagag cgtgaaagtg gtaaagctaa
    30481 cgatgttgta ggtgagcaag ttaagaaagc tgttgcaggt ttatctgaaa atcaactaaa
    30541 atcagttgta attgcttatg aaccaatctg ggcaatcgga actggtaaat catcaacatc
    30601 tgaagatgcg aatgaaatgt gtgcatttgt acgtcaaact attgctgact tatcaagcaa
    30661 agaagtatca gaagcaactc gtattcaata tggtggtagt gttaaaccta acaacattaa
    30721 agaatacatg gcacaaactg atattgatgg ggcattagta ggtggcgcat cacttaaagt
    30781 tgaagatttc gtacaattgt tagaaggtgc aaaataatca tggctaagaa accaactgcg
    30841 ttaattattt tagatggttt tgcgaaccgc gaaagcgaac atggtaatgc ggtaaaatta
    30901 gcaaacaagc ctaattttga tcgttattac aacaaatatc caacgactca aatcgaagcg
    30961 agtggcttag atgttggact acctgaagga caaatgggta actcagaagt tggtcatatg
    31021 aatatcggtg caggacgtat cgtttatcaa agtttaactc gaatcaataa atcaattgaa
    31081 gacggtgatt tctttgaaaa tgatgtttta aataatgcaa ttgcacacgt aaattcacat
    31141 gattcagcgt tacacatctt tggtttattg tctgacggtg gtgtgcacag tcattacaaa
    31201 catttatttg ctttgttaga acttgctaaa aaacaaggtg ttgaaaaagt ttacgtacac
    31261 gcatttttag atggtcgtga cgtagatcaa aaatccgctt tgaaatacat cgaagagact
    31321 gaagctaaat tcaatgaatt aggcattggt caatttgcat ctgtgtctgg tcgttattat
    31381 gcaatggacc gtgacaaacg ttgggaacgt gaagaaaaag cttacaatgc tattcgtaat
    31441 tttgatgccc caacttatgc aactgccaaa gaaggtgtag aagcaagcta taatgagggc
    31501 ttaactgacg aattcgtagt accattcatc gttgagaatc aaaatgacgg tgttaatgat
    31561 ggagatgcag tgatcttcta taatttccga cctgatagag cagcacaatt atcggaaatt
    31621 tttgcgaaca gagcattcga aggctttaaa gttgaacaag ttaaagactt attctatgca
    31681 acattcacta agtataacga caatatcgat gcggctatcg ttttcgaaaa agttgattta
    31741 aataatacaa ttggtgaaat tgcacaaaat aacaatttaa cacaattacg tattgcagaa
    31801 actgaaaaat atcctcacgt tacttacttt atgagtggtg gacgtaacga ggaatttaaa
    31861 ggtgaacgcc gtcgtttaat tgattcacct aaagttgcaa cgtatgactt gaaaccagaa
    31921 atgagtgctt atgaagttaa agatgcatta ttagaagagt taaataaagg tgacttggac
    31981 ttaattattt taaactttgc taaccctgat atggttggac atagtggtat gcttgagccg
    32041 acaatcaaag caatcgaagc ggttgatgaa tgtttgggtg aagtcgttga taagatttta
    32101 gacatggacg gttatgcaat tattactgct gaccatggta actctgatca agtattgacg
    32161 gatgatgatc aaccaatgac tacgcataca acgaacccag taccagtgat tgtaacaaaa
    32221 gaaggcgtta cacttcgaga aactggtcgc ttaggtgact tagcacctac attattagat
    32281 ttattaaatg tagaacaacc tgaagacatg acaggtgaat ctttaattaa acactaatat
    32341 tgtaaaagat gttaagtaaa cgcttaatga cacttatttt ttgaaaataa tagtaatatc
    32401 attttgttaa atgaaagaat aaagctataa taattataga ataactattt aaaggagatt
    32461 ataaacatgc caattattac agatgtttac gctcgcgaag tcttagactc tcgtggtaac
    32521 ccaactgttg aagtagaagt attaactgaa agtggcgcat ttggtcgtgc attagtacca
    32581 tcaggtgctt caactggtga acacgaagct gttgaattac gtgatggaga caaatcacgt
    32641 tatttaggta aaggtgttac taaagcagtt gaaaacgtta atgaaatcat cgcaccagaa
    32701 attattgaag gtgaattttc agtattagat caagtatcta ttgataaaat gatgatcgca
    32761 ttagacggta ctccaaacaa aggtaaatta ggtgcaaatg ctattttagg tgtatctatc
    32821 gcagtagcac gtgcagcagc tgacttatta ggtcaaccac tttacaaata tttaggtgga
    32881 tttaatggta agcagttacc agtaccaatg atgaacatcg ttaatggtgg ttctcactca
    32941 gatgctccaa ttgcattcca agaattcatg attttacctg taggtgctac aacgttcaaa
    33001 gaatcattac gttggggtac tgaaattttc cacaacttaa aatcaatttt aagcaaacgt
    33061 ggtttagaaa ctgcagtagg tgacgaaggt ggtttcgctc ctaaatttga aggtactgaa
    33121 gatgctgttg aaacaattat ccaagcaatc gaagcagctg gttacaaacc aggtgaagaa
    33181 gtattcttag gatttgactg tgcatcatca gaattctatg aaaatggtgt atatgactac
    33241 agtaagttcg aaggcgaaca cggtgcaaaa cgtacagctg cagaacaagt tgactactta
    33301 gaacaattag tagacaaata tcctatcatt acaattgaag acggtatgga cgaaaacgac
    33361 tgggatggtt ggaaacaact tacagaacgt atcggtgacc gtgtacaatt agtgggtgac
    33421 gatttattcg taacaaacac tgaaatttta gcaaaaggta ttgaaaacgg aattggtaac
    33481 tcaatcttaa ttaaagttaa ccaaatcggt acattaactg aaacatttga tgcaatcgaa
    33541 atggctcaaa aagctggtta cacagcagta gtttctcacc gttcaggtga aacagaagat
    33601 acaacaattg ctgatatcgc tgttgctaca aacgctggtc aaattaaaac tggttcatta
    33661 tcacgtactg accgtattgc taaatacaat caattattac gtatcgaaga tgaattattt
    33721 gaaactgcta aatatgacgg tatcaaatca ttctacaact tagataaata atcattttaa
    33781 acattaagta ctgccataat tttagttgag gattattatg tcggtataaa ttgaataaag
    33841 tttttgagtt cacgcttaaa aagttcacgc ttgtatttat aacctgccac agagttgaga
    33901 ctgtggtagg ttttttattt tggatggctt caaatcatga tttataaggg gcttgataaa
    33961 tcatgaggta actaataaca catatttaac ttgtattctt aaactggtat aataaattta
    34021 tgttgaaatg aatattgtat gacagggtat tcacttttat taagaggtaa aattaaataa
    34081 aggttttata gaacgtattt aaatatatga ggagtaaaca aatggctgat agaacgaata
    34141 aagaaattaa aacaggacgc tttattgcaa ctgcatcaat cgtattctca atattattga
    34201 ttattcatta ctttgtttcg ttggataatg cgactgccaa agcattactt aatttaacga
    34261 atcaaaacac ttcagataaa gcgattgatt acattttaaa cagctttaga ttcactggta
    34321 ttatgtatat tttggcttat ctagcaggct tcatcacttt ttggaatcga catacttatg
    34381 tgtggtggtt tatgtttgca gtttatgtat caaatagttt gtttacgttg attaatttat
    34441 caatcacaat tcaagcaata aaagctgcac acggtgcgta cttaacattg ccaattttaa
    34501 ttgttattat aggttcggtt gcattagcga tttatatgct tgttgtttca attaagcgta
    34561 aaagtacatt taatcgctag aaaattgatt ttaacaataa aaatatgata tactacttgt
    34621 cgtatataag gaacggagga caatttatgc atacattttt aatcgtatta ttaatcattg
    34681 attgtattgc attaataact gttgtactac tccaagaagg taaaagcagt ggactttcag
    34741 gtgccatcag tggtggtgct gagcagttat tcggtaaaca aaaacaacgt ggcgtcgatt
    34801 tattcttaaa tagattaaca attattttat caatattatt ttttgtactt atgatttgca
    34861 taagttatct tggtatgtaa ggtccggcga tgtaaatgtc gggctttttt atttataatt
    34921 aagaatgtaa tagtttaaca ataagctatg taaaatatat agcctagtta agtatgcaaa
    34981 gggagcgtta gatttatgca gataaaatta ccaaaacctt tcttttttga agaaggcaaa
    35041 cgtgccgtgt tattattaca tggatttaca ggcaattcgt ctgatgtacg tcaattaggt
    35101 cgatttttac aaaaaaaggg atatacttcg tatgcaccgc aatatgaagg tcatgcagca
    35161 ccaccagaag agatacttca atcaagtcct tttgtttggt ttaaagatgc tttagatggc
    35221 tatgactacc ttgttgaaca aggttatgat gaaatcgttg ttgctggctt gtcattaggt
    35281 ggcgattttg cattaaaatt aagcttaaat agagatgtaa agggtattgt aacgatgtgt
    35341 gcacctatgg gtggcaaaac tgaaggtgcc atttatgaag gctttttaga atatgcacgc
    35401 aattttaaaa agtatgaagg taaagatcaa gaaacgattg acaacgaaat gcatcatttt
    35461 aaaccaactg aaactttaaa agaattaagt gaagcattag gtacgattaa agatcaagtt
    35521 gatgaggtgt ttgacccaat tttagtgatt caagcagaaa acgacaatat gattgatcca
    35581 caatccgcaa attatatata tgaacatgta gactctgacg ataaaaatat caagtggtac
    35641 agtgaatctg gacatgttat tacgattgat aaagaaaaag aacaagtatt tgaagatatt
    35701 tatcaatttt tagagtcatt agattggtca gaataaaaag agattttaac attagaaagg
    35761 aggggcataa tgaatttaaa gcaatcaata gaagagatta ttaatcaacc tgaatatgaa
    35821 cctatgtcag tgtcagattt tcaagatgca ttaggtttaa gtagtgccga ctcatttaga
    35881 gatttaatta aggtgctcgt agaattagaa caatcaggat taattgaacg tacaaaaaca
    35941 gacagatatc aaaaaaagca tagttcaaaa ggtcattcaa aattgataaa gggaacgtta
    36001 agtcaaaata aaaaaggctt tgcattctta agacctgaag atgaggatat ggaagatata
    36061 tttattcccc caacaaaaat taatcgtgcc ttagatggag atactgtaat tgtagaaata
    36121 catcaatcta aaggtgaaca taaaggtaaa attgaagggg aagttaagtc gattgagaag
    36181 cattcagtaa ctcaagttgt tggtacgtat agtgaagcta gacatttcgg atttgttatt
    36241 ccagatgata aacgtattat gcaagatatt ttcattccta aaggacaaag tttaggtgca
    36301 gtagatgggc ataaggtact tgttcaaatt actaaatatg ctgatggttc agataatcca
    36361 gaaggacata tttctgctat tttaggacat aaaaatgatc ctggcgtaga tattttatct
    36421 attatctatc aacatggcat agaaattgaa tttcctgatg aagtgttaca agaagctgaa
    36481 gcagtacctg atcatattga gaatactgaa attaaaggcc gtcatgattt acgtgatgaa
    36541 ttgacaatca caattgatgg tgctgatgct aaagacttag atgacgcaat tagtgttaaa
    36601 aagttagcga acggtaatac gcaattaact gtaagtattg ctgatgtcag ttattatgta
    36661 actgaagatt cagctttaga taaagaagct tatgatagag cgacaagtgt atatcttgtt
    36721 gaccgtgtga tcccgatgat tccacatcga ttaagcaatg gtatttgttc attaaatcct
    36781 cacgttgatc gtttaacgtt aagctgtcgc atggaaattg atgctagtgg tcgcgttgtt
    36841 aaacatgaaa tttttgatag tgttatacat tctgattatc gaatgacgta tgatgcggta
    36901 aatcagatta ttactgaaaa ggatcctgcg attcgagagc agtataatga aattacgcct
    36961 atgctagatt tagcacaaga tttatctaat cgtttgattc aaatgagaaa acgacgtggt
    37021 gaaatcgatt ttgatattag tgaagcaaaa gtattagtta acgaagatgg tatacctaca
    37081 gatgttcaat taagacaacg tggcgagggt gaacgtctaa ttgaatcatt tatgttaatt
    37141 gcaaatgaaa cagttgctga acattttagt aagttagatg taccttttat ttaccgagtg
    37201 catgagcaac ctaaatcaga tcgcttaaga caattctttg attttattac aaactttggc
    37261 atcatgatta agggtactgg cgaagatatt catccaacaa cacttcaaaa ggttcaagaa
    37321 gaagtagaag gtcgacctga acaaatggtc atttcaacaa tgatgttacg ttcaatgcaa
    37381 caagcgcatt atgatgatgt gaacttggga cattttggct tatcagctga atattatacg
    37441 cattttacat caccaattag acgttatcct gatttaacag ttcatcgttt aatccgtaag
    37501 tatttaattg agaaatcaat ggataacaaa gaagtgaagc gttgggaaga caaattgcct
    37561 gagttagctg aacatacttc taaacgtgaa cgtcgtgcta ttgaggcaga acgtgatact
    37621 gatgaattga aaaaagcaga atatatgatt caacatattg gtgatgaatt tgaaggtatt
    37681 gtcagctcag tagctaactt cggtatgttc attgaattgc caaatacgat agaaggtatg
    37741 gttcatattg cgaatatgac tgatgattat taccgttttg aagagcgtca aatggcatta
    37801 attggtgagc gtcaagctaa agtatttaga attggtgaca caattaaggt taaagtgacg
    37861 catgttgatg tagatgaacg attaattgat tttcaaattg taggtatgcc tttaccgaaa
    37921 aatgatcgat cacagcgccc agcgcgaggt aagacaattc aagctaaaac gcgtggtaaa
    37981 tcattagata aatcgaaatc tgatgataaa ggtcataaga aaaaaggtaa gcaacgtaaa
    38041 ggtaaaaatg aacgtaaaaa tgacaaatca ggaaacagta aacataagcc attttataaa
    38101 gataaaagtg tgaaaaagaa agcacgtcgt aagaaaaaat aagcagcaat gaggtgagta
    38161 tgaatggcta agaagaaatc accaggtaca ttagcggaaa atcgtaaagc tagacatgat
    38221 tataatattg aagacacgat tgaagcggga attgtattgc aaggcacaga aataaaatca
    38281 attcgccgag gtagtgctaa ccttaaagat agttatgcgc aagttaaaaa cggtgaaatg
    38341 tatttgaata atatgcatat agcaccatac gaagaaggga atcgttttaa tcacgatcct
    38401 cttcgttctc gaaaattatt attgcacaag cgtgaaatca ttaaattggg tgatcaaaca
    38461 cgtgagattg gttattcgat tgtgccgtta aagctttatt tgaagcatgg acattgtaaa
    38521 gtattacttg gtgttgcacg aggtaagaaa aaatatgata aacgtcaagc tttgaaagaa
    38581 aaagcagtca aacgagatgt tgcgcgcgat atgaaagccc gttattaagc gatttagttg
    38641 cttaatcggg ctatatttga tatagttata tgtgcttttg taaattacaa aagtatgatt
    38701 tgtttgattt attatttcgg ggacgttcat ggattcgaca ggggtccccc gagctcatta
    38761 agcgtgtcgg agggttgtct tcgtcatcaa cacacacagt ttataataac tggcaaatca
    38821 aacaataatt tcgcagtagc tgcctaatcg cactctgcat cgcctaacag catttcctat
    38881 gtgctgttaa cgcgattcaa ccttaatagg atatgctaaa cactgccgtt tgaagtctgt
    38941 ttagaagaaa cttaatcaat ctagcatcat gttggttgtt tatcactttt catgatgcga
    39001 aacctttcga taaactacac acgtagaaag atgtgtatca ggacctctgg acgcgggttc
    39061 aaatcccgcc gtctccatta tatagcctgc gaccttagtg gttgtaggct ttttattttt
    39121 gagtgcacaa aaagtgcaca gatagtgcac aagatacaaa aagacacaac caattttagt
    39181 tggcagtgcc ttataagtat ttaactattt ctttctgtgt actaggatat aaatgaccat
    39241 atcggttata tacttcagtc gtatcgctgt gacctaaacg ctgagctata atcattacac
    39301 tggcccctag attaactaac atagatgcat gactatgtct taactcgtgt ataacgattc
    39361 tagggaaatt ttgtccattt ggtaattgct catccaacac ttttaatgcg ttagtaaacc
    39421 aacgatcaat ggtagactcg ctgtaagctt tatagaatgt accaaataat acataatcat
    39481 ctttaaatat gttattctct ttataccaat ttaaataacc tttgatgtca tccatcatgt
    39541 gagtaggcaa atatatatcg cgtatggctg atttcgtttt aggggctgtc acttcaccgt
    39601 gatagtccgt tttgtttata tggataaaat catcatcaaa gttaatatcg cgccatgtga
    39661 gcgctctgat ttcgcctttg cgtgctccag agtagaacaa tagtttaaag aataactttt
    39721 gttgttgtgt cactagcgca ccataaaatt gattgaattg ttctaatgtc caataattca
    39781 atcgtttctg tgattctatt tcaaaattcc ctacaagaga tgcaacattt tgttttaact
    39841 catgaaactt cattgcatga ttcagtaatg atactaaata tacatgcatc ttctttaagt
    39901 agtctccaga atgcccctct tttaacttct tattctgaaa tttcatcaca tcttgtgtag
    39961 tcattttaaa tacatccata gatttaaaat aaggtagcaa gtggttattt gtatgtgttt
    40021 ttaatgcttt tacacttgat gtctttcgac gtgctgaata ccagtctata tattcttcaa
    40081 cgagcttgtc aaaagataat ctattaaggt gtccgactcc ctctaattcg tccatcattt
    40141 cgttacattt cttaactgcg tctttacgtt gtttaaaccc cttacgtgtt atgtacttac
    40201 gagtattgct cttgtcatag taagtgatac ggaaataata agtaccgcgt ttagtgtctt
    40261 tatatatgtt atgggatagg tttaagttat gtgtcatgag tatcgccttg tttttttaaa
    40321 atatttttat tgagtaactt ttctttcata acatcgattt tattcattaa tttttggtat
    40381 tctttagagt ctataaattc tgctatttta cttcttctag tatgattgtg taatatttca
    40441 tgcttagttg aaatttcttg tatattactt ttgaggtcgt caaattgcga caacaagttt
    40501 aaaaagtaga cttcaggata ttttaatgaa atttggatta ataaatgata aataaattca
    40561 gtgagatata attgtacagg taattttttg aaatcttcgt ttagcaataa ataaacaccg
    40621 tgatggtaaa atgtcatgtt ctcatttgag atgaatgaat acatttgttc tattatacaa
    40681 tctatatttg aatctgtatg atcattaata attgtaatta aactagctac tttaaaataa
    40741 taagtatttt gctcactaga gggcatataa ttaacgataa aatcaattaa cttgtcttga
    40801 atattgtttt tcatattcac tgattttatg ttttgataaa tatcttcgta tgaaatctca
    40861 tttccatata gtaaaaaatt aatagataca ttaccatatt ctgcaatagc ttttaacctt
    40921 ttggcattgg ggattgacac ccctttttcc catcgactaa ctatactatc cgaaatatat
    40981 tttttttctt ttgttaattt tgatatttct tcgccaaatt ctcttaaatt caatccttta
    41041 gcaagtctga tacttttgat gcgtaaacca atatctgttt ttttatccat attttcactt
    41101 cctatctaat gagaatatct ataaaaactt tcgtaaaccg acgtttttgt gttgctttta
    41161 gttttcgtgt ctgttatatt atacatacag acgagaactt acgtctaggg aagaggtgat
    41221 aataagtgaa taaagtactg ggttatagga aaatgttgaa cttcacacaa caacaaatgg
    41281 caaaagagct taaaatatca gaacagtcat acagaaataa agaaaaagga aaaacggaat
    41341 ttaagaaaga agaaatgtta acttttaaaa acatacttat ttcaaaggga atgaccaata
    41401 taactttaga tgatattttt tttaattaaa atccgacgta aaactacgta aaagaggtgc
    41461 tcaaatgaca aaactagctt atccaatgtt atacattact agaaaagaaa aaggtgacac
    41521 acaaaagaaa gttgctagca aacttggtat tagtccacaa cgttaccagt taaaggaaag
    41581 tggtaaagca atatttaatt taaatgagtg tcagattctt tcagaaatgt atgatatgcc
    41641 aattgatgag ttattttcat caaaaattaa agtaggagaa taggaggcaa ggcaatgaaa
    41701 atgtacttaa cttatatctg cttagtttca ttgttaacaa t
//
LOCUS       DAPSKH010000017        39972 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPSKH010000017 DAPSKH010000000
VERSION     DAPSKH010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 39972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39972
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.017"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            146..1099
                     /locus_tag="RPH49_000997"
     CDS             146..1099
                     /locus_tag="RPH49_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124175.1"
                     /translation="MKKTLGCLLLIMLLVVAGCSFGGNHKLSSKKSEESKQETVKKES
                     EEEKDPDLEKFEEIEKKMKGIKDAPSLDKLDPLMTEKSFTNSKGIQGWKDYKELMGKV
                     ELADYRFTKDSKGSSIKDVDAFFKGKKGIKRKVIETHDDVKQVDYWYVDPDGKKIGNS
                     NTPVFYAEIMTKYKDGKLVYASVEPGSYVIHKDDAIKYDDYSKLKKLSQLTKLDHPKP
                     VPYSVAQIKSFGVPLTSVSFMTHGSKDTKDEVLPALAYFTFSPKNYEDKSNPDPKVLN
                     LVHMDFLNASSDFGNAHFVVLSKYIKEYESNYETASDDSLK"
     gene            complement(1262..1465)
                     /locus_tag="RPH49_000998"
     CDS             complement(1262..1465)
                     /locus_tag="RPH49_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HDY5124176.1"
                     /translation="MQVNKVIYILLALFLGSFGIHKFYAGKNMQGFLHLIFFWTVIPH
                     ILAIISAIITVFKPADEHGNVTL"
     gene            1764..2252
                     /locus_tag="RPH49_000999"
     CDS             1764..2252
                     /locus_tag="RPH49_000999"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDY5124177.1"
                     /translation="MAIKKLVPASHPILTKKAQAVIKFDDSLKRLLQDLEDTMYAQEA
                     AGLCAPQINQSLQVAIIDMEMEGLLQLVNPKIISQSNETITDLEGSITLPDVYGEVTR
                     SKMIVVESYDVNGNKVELTAHEDVARMILHIIDQMNGIPFTERADRILTDKEVEAYFI
                     ND"
     gene            2245..3180
                     /locus_tag="RPH49_001000"
     CDS             2245..3180
                     /locus_tag="RPH49_001000"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDY5124178.1"
                     /translation="MTKIIFMGTPDFSTTVLEMLIAEHDVIAVVTQPDRPVGRKRVMT
                     PPPVKKVAMKYDLPVYQPEKLSGSEELEQLLQLDVDLIVTAAFGQLLPESLLALPKLG
                     AINVHASLLPKYRGGAPIHQAIIDGEQETGITIMYMVKKLDAGNIISQQAIKIEENDN
                     VGTMHDKLSVLGADLLKETLPSIIEGTNESVPQDDAQATFASNIRREDERISWNKPGR
                     QVFNQIRGLSPWPVAYTTMDDTNLKIYDAELVETNKINEPGTIIETTKKAIIVATNDN
                     EAVAIKDMQLAAKKRMLAANYLSGAQNTLVGKKLI"
     gene            3177..4484
                     /gene="rsmB"
                     /locus_tag="RPH49_001001"
     CDS             3177..4484
                     /gene="rsmB"
                     /locus_tag="RPH49_001001"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDY5124179.1"
                     /translation="MIENVRSLAFDTIQDILNEGAYSNLRINEVLSENELNAMDKALF
                     TEIVYGTVKRKYTLDFYLKPFVKTKIKAWVRQLLWMSIYQYVYLDKVPNHAIINEAVE
                     IAKERGGYHNGNVVNGILRTMMRSDLPDFNEIADPKKRMAIEYSMPKWIIDHWATHYG
                     LEETETILQSFLETTSTTVRANLTRASLDDIIEKLQDEGYDVEKDHDLPYCLHIGGQP
                     IIHSRSFKDGFVSIQDKSSMFVAHIMNVDRHDHVLDACSAPGGKACHIAEVLMPEGQV
                     DASDIHDHKIDLINFNIKKLRLTNIKAFQHDATKLYDKTYDKILVDAPCSGLGVMRHK
                     PEIKYTQSKQHIESLVDLQLEILENVKNNVKIGGEIIYSTCTIEQLENENVIYTFLKN
                     NKNFEFEPFQHPITGELVKTLQIMPQDFNSDGFFITKIKRKDN"
     gene            4487..5581
                     /gene="rlmN"
                     /locus_tag="RPH49_001002"
     CDS             4487..5581
                     /gene="rlmN"
                     /locus_tag="RPH49_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002435140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDY5124180.1"
                     /translation="MITAEKKKKNKFLPNFDKQSIYSLRFDEMQNWLVEQGQQKFRAK
                     QIFEWLYQKRVDSIDEMTNLSKDLRQLLKDNFTVTTLTTVVKQESKDGTIKFLFELQD
                     GYTIETVLMRHDYGNSVCVTTQVGCRIGCTFCASTLGGLKRNLEAGEIVSQVLTVQKA
                     LDATEERVSQIVIMGIGEPFENYDEMMDFLRIVNDDNSLNIGARHITVSTSGIIPRIY
                     EFADEDIQINFAVSLHAAKDEVRSRLMPINRAYNVEKLIEAIQYYQEKTNRRVTFEYG
                     LFGGVNDQLEHARELAHLIKGLNCHVNLIPVNHVPERNYVKTAKNDIFKFEKELKRLG
                     INATIRREQGSDIDAACGQLRAKERQVETR"
     gene            5588..6331
                     /locus_tag="RPH49_001003"
     CDS             5588..6331
                     /locus_tag="RPH49_001003"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase Stp1"
                     /protein_id="HDY5124181.1"
                     /translation="MLEAQFFTDTGQHRDKNEDAGGIFYNQTNQQLLVLCDGMGGHKA
                     GEVASKFVTDELKSRFEAENLIEQHQAENWLRNNIKDINFQLYHYAQENAEYKGMGTT
                     CVCALVFEKSVVIANVGDSRAYVINSRQIEQITSDHSFVNHLVLTGQITPEEAFTHPQ
                     RNIITKVMGTDKRVSPDLFIKRLNFYDYLLLNSDGLTDYVKDNEIKRLLVKEGTIEDH
                     GNQLMQLALDNHSKDNVTFILAAIEGDKV"
     gene            6328..8322
                     /gene="pknB"
                     /locus_tag="RPH49_001004"
     CDS             6328..8322
                     /gene="pknB"
                     /locus_tag="RPH49_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase Stk1"
                     /protein_id="HDY5124182.1"
                     /translation="MIGKIINERYKIVDKLGGGGMSTVYLAEDTILNIKVAIKAIFIP
                     PREKEETLKRFEREVHNSSQLSHQNIVSMIDVDEEDDCYYLVMEYIEGPTLSEYIESH
                     GPLSVDTAINFTNQILDGIKHAHDMRIVHRDIKPQNILIDSNKTLKIFDFGIAKALSE
                     TSLTQTNHVLGTVQYFSPEQAKGEATDECTDIYSIGIVLYEMLVGEPPFNGETAVSIA
                     IKHIQDSVPNVTTDVRKDIPQSLSNVILRATEKDKANRYKTIQEMKDDLSSVLHENRA
                     NEDVYELDKMKTIAVPLKKEDLAKHISEHKSNQPKRETTQVPIVNGPAHHQQFQKPEG
                     TVYEPKPKKKSTRKIVLLSLIFSLLMIALVSFVAMAMFGNKYEETPDVIGKSVKEAEQ
                     IFNKNNLKLGKISRSYSDKYPENEIIKTTPNTGERVERGDSVDVVISKGPEKVKMPNV
                     IGLPKEEALQKLKSLGLKDVTIEKVYNNQAPKEYIANQSVTANTEIAIHDSNIKLYES
                     LGIKQVYVEDFEHKSFSKAKKALEEKGFKVESKEEYSDDIDEGDVISQSPKGKSVDEG
                     STISFVVSKGKKSDSSDVKTTTESVDVPYTGKNDKSQKVKVYIKDKDNDGSTEKGSFD
                     ITSDQRIDIPLRIEKGKTASYIVKVDGKTVAEKEVSYDEV"
     gene            8549..9424
                     /gene="rsgA"
                     /locus_tag="RPH49_001005"
     CDS             8549..9424
                     /gene="rsgA"
                     /locus_tag="RPH49_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499727.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDY5124183.1"
                     /translation="MKTGRIVKSISGVYQVDVNGERFNTKPRGLFRKKKFSPVVGDIV
                     EFDVQNINEGYIHQVYERKNELKRPPVSNIDTLVIVMSAVEPNFSTQLLDRFLVIAHS
                     YQLDARVLVTKKDKTPIEKQLEINELLKIYENIGYETEFIGNDDDRKKIVEAWPAGLI
                     VLSGQSGVGKSTFLNHYRPELNLETNDISKSLNRGKHTTRHVELFERQNGYIADTPGF
                     SALDFDHIDKDEIKDYFLELNRYGETCKFRNCNHIKEPNCNVKHQLEIGNIAQFRYDH
                     YLQLFNEISNRKVRY"
     gene            9425..10069
                     /locus_tag="RPH49_001006"
     CDS             9425..10069
                     /locus_tag="RPH49_001006"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDY5124184.1"
                     /translation="MTKLYPSLLSVDFLDLQHELKRLEEAGVDGVHFDVMDGQFVPNI
                     SIGLPILDAVRKGTTLPIDVHLMIENPEKYIASFAEHGADMISIHVESTPHIHRAIQM
                     IKHLDKKAGVVINPGTPISQIEPILDIVDYVLVMTVNPGFGGQSFIDQCVEKIAGLNA
                     IKMERQLNFDIEVDGGVNTDTAKVCVENGATMLVTGSFFFKQEDYKKVTQALKG"
     gene            10076..10717
                     /locus_tag="RPH49_001007"
     CDS             10076..10717
                     /locus_tag="RPH49_001007"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDY5124185.1"
                     /translation="MHINLLCSDRHLPQDIWAKSNEGKWGGVDRGALILLKHQIIPFF
                     SVGDFDSVSKEERQLLTEQLQIKPVQAEKADTDLALAVDKAVALGFDSITIYGATGGR
                     LDHFFGAIQLLLKKAYYKHDVHIEVIDQQNKIELLPKGQHTVEKDKSYPYISFIPMTD
                     DVELSLAGFKYNLARQMLNIGSTLTISNEIESLQAKVTVHDGLILQIRSTDLN"
     gene            complement(11077..11265)
                     /locus_tag="RPH49_001008"
     CDS             complement(11077..11265)
                     /locus_tag="RPH49_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014614133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDY5124186.1"
                     /translation="MGKQCFVTGRKASTGNRRSHALNSTKRRWNANLQKVRILVDGKP
                     KKVWVSARALKSGKVTRV"
     gene            11708..12082
                     /locus_tag="RPH49_001009"
     CDS             11708..12082
                     /locus_tag="RPH49_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDY5124187.1"
                     /translation="MTLEISNDYGKIDISNEVIASVVGGKAVECYGIVGMASRQQVRD
                     GIAEILGHENYAKGIKVTENNGVVNIDMYIIVSYGVKISEVANNVQSTVKYTLEKSLN
                     VSVNSINIYVQGVRVNNTGKKA"
     gene            12097..13743
                     /gene="fakA"
                     /locus_tag="RPH49_001010"
     CDS             12097..13743
                     /gene="fakA"
                     /locus_tag="RPH49_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase catalytic subunit FakA"
                     /protein_id="HDY5124188.1"
                     /translation="MISKINGKLFADMIIQGAQNLSNNADLVDSLNVYPVPDGDTGTN
                     MNLTMTSGREEVENNLSKNIGELGKTFSKGLLMGARGNSGVILSQLFRGFCKNIESES
                     EINSKLLAESFQAGVETAYKAVMKPVEGTILTVAKDAAQAAVEKANNTEDCIELMEYI
                     IVKANESLENTPNLLAVLKEVGVVDSGGKGLLCVYEGFLKALKGEKVEAKVAKIDKDE
                     FVHDEHDFHGVINTEDIIYGYCTEMMVRFGKNKKAFDEQEFRQDMSQFGDSLLVINDE
                     EIVKVHVHTEHPGKVFNYGQQYGELIKLKVENMREQHREVIRKEQHTAKPKMETVETA
                     IITISMGEGISEIFKSMGATHIISGGQTMNPSTEDIVKVIEQSKCKRAIILPNNKNIL
                     MASEQAASIVDAEAVVIPTKSIPQGISALFQYDVDATLEENKAQMADSVNNVKSGSLT
                     YAVRDTKIDGVEIKKDAFMGLIEDKIVSSQSDQLTTVTELLNEMLAEDSEILTVIIGQ
                     DAEQEVTDNMINWIEEQYPDVEVEVHEGGQPIYQYFFSVE"
     gene            13933..15993
                     /gene="recG"
                     /locus_tag="RPH49_001011"
     CDS             13933..15993
                     /gene="recG"
                     /locus_tag="RPH49_001011"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDY5124189.1"
                     /translation="MAKVNLIESPYSLLQLKGIGPKKIEALQQLNIHTVEDLVLYLPT
                     RYEDNTVIDLNQAEDQSNVTIEGQVYTAPVVAFFGRNKSKLTVHLMVNNIAVKCIFFN
                     QPYLKKKIELNQTITVKGKWNRVKQEITGNRVFFNSQGTQTQENADVQLEPVYRIKEG
                     IKQKQIRDQIRQALNDVTIHEWLTDELREKYKLETLDFTLNTLHHPKSKEDLLRARRT
                     YAFTELFLFELRMQWLNRLEKSSDEAIEIDYDLDQVKSFIDRLPFELTEAQKSSVNEI
                     FRDLKAPIRMHRLLQGDVGSGKTVVAAICMYALKTAGYQSALMVPTEILAEQHAESLM
                     ALFGDSMNVALLTGSVKGKKRKILLEQLENGTIDCLIGTHALIQDDVIFHNVGLVITD
                     EQHRFGVNQRQLLREKGAMTNVLFMTATPIPRTLAISVFGEMDVSSIKQLPKGRKPII
                     TTWAKHEQYDKVLMQMTSELKKGRQAYVICPLIESSEHLEDVQNVVALYESLQQYYGV
                     SRVGLLHGKLSADEKDEVMQKFSNHEIDVLVSTTVVEVGVNVPNATFMMIYDADRFGL
                     STLHQLRGRVGRSDQQSYCVLIASPKTETGIERMTIMTQTTDGFELSERDLEMRGPGD
                     FFGVKQSGLPDFLVANLVEDYRMLEVARDEAAELIQSGVFFENTYQHLRHFVEENLLH
                     RSFD"
     gene            16196..16768
                     /gene="fapR"
                     /locus_tag="RPH49_001012"
     CDS             16196..16768
                     /gene="fapR"
                     /locus_tag="RPH49_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription factor FapR"
                     /protein_id="HDY5124190.1"
                     /translation="MRGETLKLKKDKRREAIRQQIDSNPFITDHELSDLFQVSIQTIR
                     LDRTYLNIPELRKRIKLVAEKNYDQISSIEEQEFIGDLIQVNPNVKAQSILDIASDSV
                     FHKTGIARGHVLFAQANSLCVALIKQPTVLTHESSIQFIEKVKLNDTVRAEARVVNQT
                     AKHYYVEVKSYVKHTLVFKGNFKMFYDKRG"
     gene            16773..17759
                     /gene="plsX"
                     /locus_tag="RPH49_001013"
     CDS             16773..17759
                     /gene="plsX"
                     /locus_tag="RPH49_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDY5124191.1"
                     /translation="MVKLAIDMMGGDNAPDIVLEAVQKAVEDFKDLEIILFGDEKKYN
                     LNHERIEFRHCSEKIEMEDEPVRAIKRKKDSSMVKMAEAVKSGEADGCVSAGNTGALM
                     SAGLFIVGRIKGVARPALVVTLPTIDGKGFVFLDVGANADAKPEHLLQYAQLGDIYAQ
                     KIRGIDNPKISLLNIGTEPAKGNSLTKKSYELLNHDHSLNFVGNIEAKTLMDGDTDVV
                     VTDGYTGNMVLKNLEGTAKSIGKMLKDTIMSSTKNKLAGAILKKDLAEFAKKMDYSEY
                     GGSVLLGLEGTVVKAHGSSNAKAFYSAIRQAKIAGEQNIVQTMKETVGESNE"
     gene            17752..18678
                     /gene="fabD"
                     /locus_tag="RPH49_001014"
     CDS             17752..18678
                     /gene="fabD"
                     /locus_tag="RPH49_001014"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDY5124192.1"
                     /translation="MSKTAIIFPGQGAQKVGMAQDLFNNNDQATEILTSAANTLDFDI
                     LETMFTDEEGKLGETENTQPALLTHSSALLAALKNLNPDFTMGHSLGEYSSLVAADVL
                     SFEDAVKIVRKRGQLMAQAFPTGVGSMAAVLGLDFDKVDEICKSLSSDDKIIEPANIN
                     CPGQIVVSGHKALIEELVEKGKSLGAKRVMPLAVSGPFHSSLMKVIEEDFASYINQFE
                     WRDAKFPVVQNVNAQGETDKEVIKSNMVKQLYSPVQFINSTEWLIDQGVDHFIEIGPG
                     KVLSGLIKKINRDVKLTSIQTLEDVKGWNEND"
     gene            18671..19405
                     /gene="fabG"
                     /locus_tag="RPH49_001015"
     CDS             18671..19405
                     /gene="fabG"
                     /locus_tag="RPH49_001015"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDY5124193.1"
                     /translation="MTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGIKEKAEAVV
                     EEIKAKGVDSFAIQANVADADEVKAMIKEVVSQFGSLDVLVNNAGITRDNLLMRMKEQ
                     EWDDVIDTNLKGVFNCIQKATPQMLRQRSGAIINLSSVVGAVGNPGQANYVATKAGVI
                     GLTKSAARELASRGITVNAVAPGFIVSDMTDALSDELKEQMLTQIPLARFGQDTDIAN
                     TVAFLASDKAKYITGQTIHVNGGMYM"
     gene            19840..20073
                     /locus_tag="RPH49_001016"
     CDS             19840..20073
                     /locus_tag="RPH49_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002510960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDY5124194.1"
                     /translation="MENFDKVKDIIVDRLGVDADKVTEDASFKDDLGADSLDIAELVM
                     ELEDEFGTEIPDEEAEKINTVGDAVKFINSLEK"
     gene            20189..20920
                     /locus_tag="RPH49_001017"
     CDS             20189..20920
                     /locus_tag="RPH49_001017"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDY5124195.1"
                     /translation="MSKQKKSEIVNRFRKRFDTKMTELGFTYQNIDLYQQAFSHSSFI
                     NDFNMNRLDHNERLEFLGDAVLELTVSRYLFDKHPNLPEGNLTKMRATIVCEPSLVIF
                     ANKIGLNEMILLGKGEEKTGGRTRPSLISDAFEAFIGALYLDQGLDIVWKFAEKVIFP
                     HVEQNELLGVVDFKTQFQEYVHQQNKGDVTYNLIKEEGPAHHRLFTSEVILQGEAIAE
                     GKGKTKKESEQRAAESAYKQLKQIK"
     gene            21067..24633
                     /gene="smc"
                     /locus_tag="RPH49_001018"
     CDS             21067..24633
                     /gene="smc"
                     /locus_tag="RPH49_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDY5124196.1"
                     /translation="MVYLKSIDAIGFKSFADQTNVQFDKGVTAIVGPNGSGKSNITDA
                     IKWVLGEQSAKSLRGSKMEDIIFSGAEHRKAQNYAEVQLRLDNHSKKLSVDENEVIVT
                     RRLYRSGESEYYINNDRARLKDIADLFLDSGLGKEAYSIISQGRVDEILNAKPIDRRQ
                     IIEESAGVLKYKKRKAESLNKLDQTEDNLTRVEDILYDLEGRVEPLKEEAAIAKEYKT
                     LSHQMKHSDIVVTVHDIDQYTNDNRQLDQRLNDLQGQQANKEADKQRLSQQIQQYKGK
                     RHQLDNDVESLNYQLVKATEAFEKYTGQLNVLEERKKNQSETNARYEEEQENLMELLE
                     NISNEISEAQDTYKSLKSKQKELNAVIRELEEQLYVSDEAHDEKLEEIKNEYYTLMSE
                     QSDVNNDIRFLKHTIEENEAKKSRLDSRLVEVFEQLKDIQGQIKTTKKEYQQTNKELS
                     AVDKEIKNIEKDLTDTKKAQNEYEEKLYQAYRYTEKMKTRIDSLATQEEEYTYFFNGV
                     KHILKAKNKELKGIHGAVAEIIDVPSKLTQAIETALGASLQHVIVDSEKDGRQAIQFL
                     KERNLGRATFLPLNVIQSRVVATDIKSIAKEANGFISIASEAVKVAPEYQNIIGNLLG
                     NTIIVDHLKHANELARAIKYRTRIVTLEGDIVNPGGSMTGGGARKSKSILSQKDELTT
                     MRHQLEDYLRQTESFEQQFKELKIKSDQLSELYFEKSQKHNTLKEQVHHFEMELDRLT
                     TQETQIKNDHEEFEFEKNDGYTSDKSRQTLSEKETHLESIKASLKRLEDEIERYTKLS
                     KEGKESVTKTQQTLHQKQSDLAVVKERIKTQQQTIDRLNNQNQQTKHQLKDVKEKIAF
                     FNSDEVMGEQAFQNIKDQINGQQETRTRLSDELDKLKQQRIELNEQIDAQEAKLQVCH
                     QDILAIENHYQDIKAEQSKLDVLIHHAIDHLNDEYQLTVERAKSEYTSDESIDALRKK
                     VKLMKMSIDELGPVNLNAIEQFEELNERYTFLSEQRTDLRKAKETLEQIISEMDQEVT
                     ERFKETFHAIQGHFTAVFKQLFGGGDAELQLTEADYLTAGIDIVVQPPGKKLQHLSLL
                     SGGERALTAIALLFAILKVRSAPFVILDEVEAALDEANVIRYAKYLNELSDETQFIVI
                     THRKGTMEFADRLYGVTMQESGVTKLVSVNLNTIDDVLKEEQ"
     gene            24633..25883
                     /gene="ftsY"
                     /locus_tag="RPH49_001019"
     CDS             24633..25883
                     /gene="ftsY"
                     /locus_tag="RPH49_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDY5124197.1"
                     /translation="MSFFKRLKDKFATNKENEEVKSLTEEQGQDKLEDTHSEGSTQDV
                     NDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQ
                     LNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREV
                     IVEKIVEIYHQEDDNSEAMNLEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVM
                     LAAGDTFRAGAIDQLKVWGERVGVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDT
                     AGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNALSQARNFKEVTNVT
                     GIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQ
                     NEEITTVENDQIVTEEKDDNHGAK"
     gene            25870..26202
                     /locus_tag="RPH49_001020"
     CDS             25870..26202
                     /locus_tag="RPH49_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDY5124198.1"
                     /translation="MGQNDLVKTLRMNYLFDFYQSLLTNKQRNYLELFYLEDYSLSEI
                     ADTFNVSRQAVYDNIRRTGDLVEDYEKKLELYQKFEQRREIYDEMKQHLSNPEQIQRY
                     IQQLEDLE"
     gene            26228..27595
                     /gene="ffh"
                     /locus_tag="RPH49_001021"
     CDS             26228..27595
                     /gene="ffh"
                     /locus_tag="RPH49_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002457378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDY5124199.1"
                     /translation="MAFEGLSERLQATMQKMRGKGKLTEADIKIMMREVRLALLEADV
                     NFKVVKEFIKTVSERALGSDVMQSLTPGQQVIKIVQDELTKLMGGENSSINMSNKPPT
                     VVMMVGLQGAGKTTTAGKLALLMRKKYNKKPMLVAADIYRPAAINQLQTVGKQIDIPV
                     YSEGDQVKPQQIVTNALKHAKEEHLDFVIIDTAGRLHIDEALMNELKEVKDIAKPNEI
                     MLVVDSMTGQDAVNVAESFDDQLDVTGVTLTKLDGDTRGGAALSIRSVTQKPIKFVGM
                     SEKLDGLELFHPERMASRILGMGDVLSLIEKAQQDVDQEKAKDLEKKMRESSFTLDDF
                     LEQLDQVKNLGPLDDIMKMIPGMNKMKGLDKLNMSEKQIDHIKAIIQSMTPAERNNPD
                     TLNVSRKKRIAKGSGRSLQEVNRLMKQFNDMKKMMKQFTGGGKGKKGKRNQMQNMLKG
                     MNLPF"
     gene            28030..28305
                     /gene="rpsP"
                     /locus_tag="RPH49_001022"
     CDS             28030..28305
                     /gene="rpsP"
                     /locus_tag="RPH49_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDY5124200.1"
                     /translation="MAVKIRLTRLGSKRNPFYRIVVADARSPRDGRIIEQIGTYNPTS
                     ANAPEIKVDEALALKWLNDGAKPTDTVHNILSKEGIMKKFDEQKKAK"
     gene            28493..28996
                     /gene="rimM"
                     /locus_tag="RPH49_001023"
     CDS             28493..28996
                     /gene="rimM"
                     /locus_tag="RPH49_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDY5124201.1"
                     /translation="MRVEVGQIVNTHGIKGEIKVKSNSDFTDVRFQPGQVLTVVHNNN
                     DLEYTVKSHRVHKGLHMLTFEGINNINDIEHLKGSSIYQERDHEDIVLEENEFYYSDI
                     IGCTVFDDQETPIGRVINIFETGANDVWVIKGSKEYLIPYIADVVKEVDVENKKIIIT
                     PMEGLLD"
     gene            28996..29733
                     /gene="trmD"
                     /locus_tag="RPH49_001024"
     CDS             28996..29733
                     /gene="trmD"
                     /locus_tag="RPH49_001024"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDY5124202.1"
                     /translation="MKIDYLTLFPEMFDGVLNHSIMKRAQENNKLQINTVNFRDYAIN
                     KHNQVDDYPYGGGQGMVLKPEPVFNAMEDLDVTEQTRVILMCPQGEPFSHQKAVELSK
                     ADHIVFICGHYEGYDERIRTHLVTDEISMGDYVLTGGELPAMTMTDAIVRLIPGVLGN
                     EQSHQDDSFSDGLLEFPQYTRPREFKGLTVPDVLLSGNHANIDAWRHEQKLIRTYNKR
                     PDLIEKYPLTNADKQILERYKIGLKKG"
     gene            29836..30186
                     /gene="rplS"
                     /locus_tag="RPH49_001025"
     CDS             29836..30186
                     /gene="rplS"
                     /locus_tag="RPH49_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011303276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDY5124203.1"
                     /translation="MTNHKLIEAVTKSQLRTDLPSFRPGDTLRVHVRIIEGTRERIQV
                     FEGVVIKRRGGGVSETFTVRKISSGVGVERTFPLHTPKIEKIEVKRRGKVRRAKLYYL
                     RSLRGKAARIQEIR"
     gene            complement(30427..33033)
                     /gene="yfhO"
                     /locus_tag="RPH49_001026"
     CDS             complement(30427..33033)
                     /gene="yfhO"
                     /locus_tag="RPH49_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoteichoic acid-specific glycosyltransferase
                     YfhO"
                     /protein_id="HDY5124204.1"
                     /translation="MLKKWLNSNVKQFFVITFISVILTLILFSTHIYDYIVNGTVFSG
                     AGDGFRQMMPFQMYLYEHLSSFSSLYDASFGLGGDYMKGLSYYYSLSPLMWLNFLFIK
                     IGETVGIFNPTTIHFWPTNQLIMAMIRAIITFVVTFYLFKILHFKRSTNMIATILYGM
                     STVVIYFNFTWSFYGNLLYLLPLSILGLERYFQQRKIGIFIVAIALTLFSNFYFSYYQ
                     AIIIGCYYLYRLIFTYKYDIVSRTQKLICVISAAVLSVLSSVFGLFTGISAFLENDRK
                     QNPNVDIPFLTPLDYHYFFFSDGFYITISILTIVALLSFKLYRFYFYRLFAIVTWILF
                     IGSLSQYFDSAFNGFSFPERRWVYILALSSSALCGLFIQHLSTLNMKYYLIRTIPVSI
                     IALLYVLLSPTHPLVLIVGIILLMVLAVILKFSLWRYKKLTVVLIVLIVMIQQIVILD
                     NNKNMAIKPYQQSISTLKQHDYHSNYVNQLIKKINQNATGPFNRIDYMSDYALNSPFI
                     YHYNGISLYSSIFNGDILKYYDKTLQINMPIDKNSTYRLLGNRQNLLSLWNVNDRIRV
                     NHDYNLPYGFKINSEHKDNKVRWIHSKNTIHYPSAHITNKVFSNKELKSPLDKEQAML
                     QGIVSNNTKDVNTHFKANKNLLSDSTIKLNSAAWQSPSKHLLQVKQNNGGLTVQLPKS
                     VSNQFKDLYFEMDLELLSPDKAHYVKVNEYTLERNKLTYKYRRFVTPVTIRIKSSDAI
                     KLSLPKGKYRVNLKGIYGEDYTTLKDTSNSLEAVKVSKTKQGYTITKNKNSSGYIVLP
                     TAYNQGMKATSGDQSLKVEQVNGVMTGIKAPKNITKIQLSYTPPYYYLLITITIFGII
                     CSIIFTRWVRQK"
     gene            33434..34318
                     /gene="ylqF"
                     /locus_tag="RPH49_001027"
     CDS             33434..34318
                     /gene="ylqF"
                     /locus_tag="RPH49_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDY5124205.1"
                     /translation="MVIQWYPGHMAKAKREVSEQLKKVDVVFELVDARIPYSSRNPMI
                     DEVINQKPRAVILNKKDMSNLNEMSKWEQFFIDKGYYPVSVDAKHGKNLKKVEAAAIK
                     ATAEKFEREKAKGLKPRAIRAMIVGIPNVGKSTLINKLAKRSIAQTGNKPGVTKQQQW
                     IKVGNALQLLDTPGILWPKFEDEEVGKKLSLTGAIKDSIVHLDEVAIYGLNFLIQNDL
                     ARLKAHYKIEVPEDAEIIAWFDAIGKKRGLIRRGNEIDYEAVIELIIYDIRNAKIGNY
                     CFDIFKDMTEELANDANN"
     gene            34302..35069
                     /locus_tag="RPH49_001028"
     CDS             34302..35069
                     /locus_tag="RPH49_001028"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDY5124206.1"
                     /translation="MTLTIKEVTQLINAVNTIEELENHECFLDERKGVQNAIARRRKA
                     LEQEQALKEKYAEMTYFENEILKEHPNAIICGIDEVGRGPLAGPVVACATILNSNHNY
                     LGLDDSKKVPVTKRLELNEALKNEVTAFAYGIATAEEIDEFNIYKATQIAMQRAIDGL
                     SVQPTHLLIDAMTLDNALTQVSLIKGDARSVSIAAASIMAKVFRDDYMTQLSKDYPEY
                     GFEKNAGYGTKQHLLAIDDIGIMKEHRKSFEPIKSLL"
     gene            35178..36344
                     /gene="sucC"
                     /locus_tag="RPH49_001029"
     CDS             35178..36344
                     /gene="sucC"
                     /locus_tag="RPH49_001029"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006190114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDY5124207.1"
                     /translation="MNIHEYQGKEIFRSMGVAVPEGRVAFTAEEAVEKAKELNSDVYV
                     VKAQIHAGGRGKAGGVKIAKSLSEVETYAKELLGKTLVTHQTGPEGKEIKRLYIEEGC
                     AIQKEYYVGFVIDRATDQVTLMASEEGGTEIEEVAAKTPEKIFKETIDPVIGLSPFQA
                     RRIAFNINIPKKSVNKAAKFLLALYNVFIEKDCSIVEINPLVTTADGDVLALDAKINF
                     DDNALFRHKDVVELRDLEEEDPKEIEASKHDLSYIALDGDIGCMVNGAGLAMATMDTI
                     NHFGGNPANFLDAGGSATREKVTEAFKIILGDENVKGIFVNIFGGIMKCDVIAEGIVE
                     AVKEVDLTLPLVVRLEGTNVELGKKILKDSGLAIEPAATMAEGAQKIVKLVKEA"
     gene            36366..37274
                     /gene="sucD"
                     /locus_tag="RPH49_001030"
     CDS             36366..37274
                     /gene="sucD"
                     /locus_tag="RPH49_001030"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDY5124208.1"
                     /translation="MSVFIDKNTKVMVQGITGSTALFHTKQMLDYGTKIVAGVTPGKG
                     GQVVEGVPVFNTVEEAKNETGATVSVIYVPAPFAADSILEAADADLDMVICITEHIPV
                     LDMVKVKRYLQGRKTRLVGPNCPGVITADECKIGIMPGYIHKKGHVGVVSRSGTLTYE
                     AVHQLTEEGIGQTTAVGIGGDPVNGTNFIDVLKAFNEDDETKAVVMIGEIGGTAEEEA
                     AEWIKANMTKPVVGFIGGQTAPPGKRMGHAGAIISGGKGTAEEKIKTLNSCGVKTAAT
                     PSEIGSTLIEAAKEAGIYESLLTVNK"
     gene            37501..38619
                     /locus_tag="RPH49_001031"
     CDS             37501..38619
                     /locus_tag="RPH49_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDY5124209.1"
                     /translation="MNKQQSKVRYSIRKVSIGILSISIGMFLALGMSNKAYADEIDKS
                     KDFTRGYEQNVFAKSELNANKNTTKDKIKNEGVVKTSDTSLKLDNKSAISNGNEINQD
                     IKISNTPKNSSQGNNLVVNNNEPTKEIKIANLEAQNSNQKKTNKVTNNYFGYYSFREA
                     PKTQIYTVKKGDTLSAIALKYKTTVSNIQNTNNIANPNLIFIGQKLKVPMTPLVEPKP
                     NTVSSNNKSNSNSSTLNYLKTLENRGWDFDGSYGWQCFDLVNVYWNHLYGHGLKGYGA
                     KDIPYANNFNSEAKIYHNTPTFKAEPGDLVVFSGRFGGGYGHTAIVLNGDYDGKLMKF
                     QSLDQNWNNGGWRKSEVAHKVVHNYENDMIFIRPFKKA"
     gene            38647..39891
                     /gene="fmhC"
                     /locus_tag="RPH49_001032"
     CDS             38647..39891
                     /gene="fmhC"
                     /locus_tag="RPH49_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FemA/FemB family glycyltransferase FmhC"
                     /protein_id="HDY5124210.1"
                     /translation="MKFTTLSEEEFTNYTKKHFKHYTQSIELYNYRNKINHEAHIVGV
                     KNDKNEVIAACLLTEARIFKFYKYFYSHRGPLLDYFDAKLVCYFFKELSKFIYKNRGV
                     FILVDPYLIENLRDANGRVIKNYNNSVIVKMLGKIGYLHQGYTTGYSNKSQIRWISVL
                     DLKDKDENQLLKEMEYQTRRNIKKTIEIGVKVEDLSIEETNRFYKLFQMAEEKHGFHF
                     MNEDYFKQMQEIYKGKAMLKIACIDLNEYQDKLKIQLLKIENEMMTVNRSLNENPNSK
                     KNKSKLNQLNMQLSSINNRISKTEELILEDGPVLDLAAALFICTDDEVYYLSSGSNPK
                     YNQYMGAYHLQWHMIKYAKSHNINRYNFYGITGVFSNEADDFGVQQFKKGFNAHVEEL
                     IGDFIKPVRPILFKFAKLIYKV"
BASE COUNT        14966 a         5326 c         7623 g        12057 t
ORIGIN      
        1 ttattagaca aaacaatttt cttaaattat caattaaagt atttaaaaat attgatggtt
       61 aatgtaaaat atcaatataa ataagttttt taaatttatg tatgtttatt tgattcaaac
      121 aaaataactt aagaggagaa agtttatgaa aaagacactg ggatgtttac ttttaattat
      181 gcttttagtc gtagcaggtt gttcttttgg tggtaatcat aaattatcat caaagaaatc
      241 agaagaatca aaacaagaaa ctgtaaaaaa agaatcggaa gaagagaaag acccagattt
      301 agagaaattt gaagaaatag agaagaaaat gaaaggaatt aaagatgcgc catctctaga
      361 taagttggat ccattaatga cagaaaagtc gtttacgaat agtaaaggga ttcaaggatg
      421 gaaagattac aaagaattaa tgggtaaagt ggaacttgca gattatagat ttacaaaaga
      481 ttcaaaagga tcttcaataa aagatgttga tgcattcttt aaaggtaaga aaggtataaa
      541 aaggaaagtg attgaaacac acgatgatgt aaaacaagtt gattattggt atgtagatcc
      601 agatggaaag aaaattggca attcaaacac acctgttttt tacgcagaaa ttatgacaaa
      661 atataaagat ggaaagttag tttatgcatc agtcgaacca ggttcttacg taatacataa
      721 agatgatgca attaaatatg acgattattc taagttaaaa aaattaagtc aactaactaa
      781 acttgatcat ccaaaaccag ttccatatag cgtagctcaa atcaaatctt tcggagtacc
      841 tttaacaagc gtttcattta tgacacatgg atcaaaggat actaaagatg aagtgttgcc
      901 ggcattggcc tatttcactt tttcaccaaa aaattatgaa gacaagtcta atccagatcc
      961 aaaagtttta aatttagtac atatggattt cttaaatgca tctagtgatt ttggtaacgc
     1021 acattttgtt gttttaagta aatatattaa agagtatgaa tcaaactatg aaacagcgtc
     1081 agatgattct ttaaaatagt atttactgtg tgaaaaataa atagtgtact acattaaata
     1141 atcgcaataa taatcccgat aaacaatcag cattactgct tatcatatag agttcgtaat
     1201 atctataact ctatgattcg caattaataa atgattgtca tcgggattta tttttatcaa
     1261 tttataatgt aacattacca tgttcgtcag ctggtttgaa aacagtaatt atcgcactaa
     1321 taattgctaa tatatgtggg atgactgtcc aaaagaatat taagtgtagg aaaccttgca
     1381 tgtttttgcc ggcataaaat ttatgaatac caaaactacc taagaacaat gctaataaaa
     1441 tataaataac tttgtttact tgcatttctt tccctccagt tgaattgctt ataatgacat
     1501 taacttctct ttttattata cccactttta gttcaaacat tctagtttaa gcatttccaa
     1561 tcatctagat ttcagttatt caatccttac aataaattta ggattacact tcagttgcat
     1621 tgtattattt tacgtgtgaa atatacgtaa tgaatcacat gacaatcttt aaattgaaaa
     1681 atatacattc tatgatgtaa ggtcgcattt ttaatatatt tacgttataa tggtttgatg
     1741 aattttattg aggagtaaga gctatggcga ttaaaaagtt agtaccagca tcgcatccta
     1801 ttttaacgaa aaaagcgcaa gcagttataa aatttgatga ttcgttaaaa agattattac
     1861 aagatttaga agatacaatg tatgcacaag aagcagctgg cttatgtgca cctcaaatta
     1921 atcagtcatt gcaagtggca atcattgata tggaaatgga aggattatta caacttgtta
     1981 atccgaaaat tattagtcaa tcaaatgaaa cgataacaga cttagaaggt tcaattacat
     2041 tgccagatgt ttacggcgaa gtgacaagaa gtaaaatgat cgttgtcgaa agttatgacg
     2101 tcaatgggaa caaagttgaa ctaactgcac atgaagatgt agcaagaatg attttgcata
     2161 ttatagatca aatgaacggt atccctttta cagaacgtgc ggaccgtatt ttaacagata
     2221 aagaagtgga ggcatatttt ataaatgact aaaataatat ttatgggtac accagacttt
     2281 tcaacaactg ttttagaaat gcttattgca gaacatgatg tcattgcagt cgtaacgcaa
     2341 ccagatcgac ctgttggacg taaacgtgtt atgacaccac caccagttaa aaaagttgca
     2401 atgaaatatg atttacctgt atatcagcct gaaaaactaa gtggatcaga agaattagaa
     2461 caattgcttc aattagatgt agatttaatt gtaactgctg cttttggaca attattacct
     2521 gaatcattgt tggcattacc aaaacttggc gcaattaatg tacatgcatc attgttaccg
     2581 aagtatagag gtggtgcacc aattcatcag gcaattatcg atggtgaaca agaaaccggc
     2641 ataacaatta tgtatatggt taaaaaatta gatgcgggta atattatttc gcaacaagca
     2701 attaaaatag aagaaaatga taatgtcggt acgatgcatg ataaattaag tgtattaggg
     2761 gcagatttat taaaagaaac tttaccatct attatagagg gcacaaatga aagtgtacct
     2821 caagatgatg cgcaagcaac atttgcttcc aatattcgac gcgaagatga gcgaattagc
     2881 tggaataaac caggaagaca agtgtttaat caaattcgag gattatcacc atggccagtt
     2941 gcttatacaa ctatggatga cactaacttg aaaatatacg atgctgaact cgttgagact
     3001 aataagataa acgagcctgg aacaattata gaaacgacta aaaaagccat tattgttgct
     3061 acaaatgata atgaagctgt tgcaattaaa gatatgcaat tggctgcgaa aaagagaatg
     3121 ttagctgcca attatttaag tggtgcgcaa aacacactag tagggaagaa acttatatga
     3181 tagaaaacgt gagaagtctt gcttttgaca cgattcaaga tatattaaat gaaggtgcgt
     3241 atagtaactt gcgtatcaat gaagtgttgt cagaaaatga attaaatgca atggataaag
     3301 ctttatttac agaaattgtc tacggaaccg ttaaaagaaa atatacgtta gatttttatt
     3361 taaagccttt tgtgaaaaca aagattaagg catgggttag gcaattatta tggatgagta
     3421 tttatcaata tgtttattta gataaagttc caaatcatgc cattattaat gaagcagttg
     3481 aaatagcaaa agaacgcggt ggctatcata atggtaatgt cgtaaatggt attttacgta
     3541 caatgatgcg tagtgactta cctgatttta atgaaattgc agatcctaaa aaaagaatgg
     3601 caatcgagta tagtatgccg aagtggatta tagatcattg ggcaacacat tatggtctcg
     3661 aagaaactga aacaatctta cagtcatttt tagaaacgac atctacaact gtgcgtgcca
     3721 acctgacgcg agcatcatta gatgatatta ttgaaaagtt gcaagacgaa ggttatgacg
     3781 ttgaaaaaga tcatgactta ccttattgtc tccatatagg aggacaacca attattcatt
     3841 ctcgttcatt taaggatgga ttcgtttcaa ttcaagataa aagctcaatg tttgttgcgc
     3901 acattatgaa tgtagaccga catgatcacg tattagatgc atgtagtgca cctggcggta
     3961 aggcttgtca cattgctgaa gttttaatgc cagaagggca agttgacgct tcagatatac
     4021 atgatcacaa aatagactta attaatttta atataaaaaa attacgatta acaaatatta
     4081 aagcttttca acatgatgcg acaaaacttt atgataaaac atacgataag atacttgttg
     4141 atgcaccatg tagcggatta ggtgtaatga gacataagcc ggagattaag tatactcaaa
     4201 gcaaacaaca tattgagtca ctagttgatt tacagcttga aatattggaa aatgtaaaaa
     4261 acaatgtaaa aataggtggc gaaatcatct attcaacatg tacaatagag caactagaaa
     4321 atgaaaacgt gatttatacg tttttgaaaa ataataaaaa cttcgaattt gaaccgtttc
     4381 aacatccgat aactggagag ttggtcaaaa cgttacaaat catgccgcaa gactttaatt
     4441 cagatggatt ctttatcact aagataaaaa gaaaggacaa ttaggaatga taactgctga
     4501 aaagaaaaag aagaataaat ttcttccaaa ttttgacaag caatcaatat attcattgcg
     4561 atttgacgaa atgcaaaact ggctcgttga acaagggcaa caaaaatttc gagcgaaaca
     4621 gatttttgaa tggttatatc aaaaaagagt agattcgatt gatgaaatga cgaacttatc
     4681 gaaagactta cgacagctct taaaagataa ctttactgtt acaactttaa caactgtagt
     4741 aaaacaagaa agtaaagacg gtacaattaa attcttattt gaattacaag atggctatac
     4801 aattgaaact gttttaatga gacatgatta tggaaattca gtatgtgtaa caacacaagt
     4861 aggttgtcgt atcggatgta cgttttgtgc ttctacactt ggcggcttaa aaagaaacct
     4921 tgaagctggc gaaattgttt cacaagtttt aacagttcaa aaagcccttg atgctacaga
     4981 agagcgcgta tctcaaattg tcataatggg tatcggtgaa ccatttgaaa attatgatga
     5041 aatgatggac tttttaagaa tcgtcaatga tgataacagt ttaaatattg gtgcacgtca
     5101 cattacagta tcaacatcag gtatcattcc tagaatatat gaatttgcgg atgaagatat
     5161 tcaaattaat tttgctgtaa gcttacacgc cgcaaaagat gaagtgcgat cacgcttgat
     5221 gccaattaac cgtgcatata atgttgagaa gttaatcgaa gcaattcaat attatcaaga
     5281 aaaaacaaat cgtcgtgtta cttttgaata tggtctgttt ggtggtgtaa atgaccaact
     5341 agaacatgca agagaattag cacatttaat aaaaggctta aattgccatg ttaacttaat
     5401 tcctgtcaac catgttccag aaagaaatta tgtaaaaacg gctaaaaatg atatctttaa
     5461 atttgaaaaa gaattaaaga gactaggaat taatgccaca atacgtcgtg aacaaggttc
     5521 ggatattgac gcagcttgtg gtcaattaag agcaaaggaa cgacaagtag aaacgaggta
     5581 aagacaaatg ctagaggcac aattttttac tgatactgga caacatagag ataagaatga
     5641 agatgcgggt ggtatttttt ataatcaaac taatcaacaa cttttagttc tgtgtgatgg
     5701 tatgggcggc cataaagcag gagaagttgc aagtaaattt gttacagatg agttgaaatc
     5761 ccgttttgaa gcggaaaatc ttatagaaca acatcaagct gaaaattggt tgcgtaataa
     5821 tataaaagat ataaattttc agttatatca ctatgcacaa gaaaatgcag aatataaagg
     5881 tatgggtaca acatgtgttt gtgcacttgt ttttgaaaaa tcagttgtga tagcaaatgt
     5941 cggtgattct agagcctatg ttattaatag tcgacaaatt gaacaaatta ctagtgatca
     6001 ctcatttgtt aatcatcttg ttttaacggg tcaaattacg ccggaagaag catttacaca
     6061 tccacaacgt aatattatta caaaggtgat gggcacagat aaacgtgtga gtccagattt
     6121 gtttattaag cgattaaatt tttatgatta tttattatta aattcagatg gattaactga
     6181 ttatgttaaa gacaatgaaa ttaagcgttt gttagtaaaa gaaggtacaa tagaagatca
     6241 tggtaatcaa ttaatgcaat tggcattaga taaccattcg aaagataacg ttactttcat
     6301 actcgcggct attgaaggtg ataaagtatg ataggtaaaa taataaatga acgatataaa
     6361 attgtagata agcttggcgg cggtggcatg agtaccgttt atcttgcaga agatacgata
     6421 cttaacatta aagttgcaat taaggcgatt tttataccac ctagagaaaa agaagaaaca
     6481 ttaaaacgtt ttgaacgaga agtacataac tcatcacagc tatcacatca aaatatagta
     6541 agtatgatcg atgttgatga agaagatgac tgttactact tagtaatgga atatattgaa
     6601 ggtccgactt tgtctgagta tattgaaagt catgggccat taagtgttga cacggcgatt
     6661 aattttacga atcaaatatt ggatggcatt aaacatgcgc atgatatgcg tattgtacat
     6721 agagatatta agccacaaaa tatattaatt gacagcaata aaacgttgaa aatatttgat
     6781 tttggaattg ctaaagcttt aagtgagacg tctttaactc agactaatca tgtgttaggt
     6841 actgtgcagt acttttcgcc agaacaagca aaaggtgagg caacggatga atgtacagat
     6901 atttattcta taggtattgt gttatatgaa atgcttgttg gtgagccgcc atttaatgga
     6961 gaaactgcag ttagcattgc gattaaacat attcaggatt ctgttccaaa tgtgacaaca
     7021 gatgtacgta aggatattcc gcaatcttta agtaatgtca ttttacgcgc tacagaaaaa
     7081 gacaaagcga atcgttacaa aacaattcaa gaaatgaaag atgatttgag tagtgtttta
     7141 catgaaaatc gagcgaatga agatgtctat gaactcgata aaatgaaaac gatagcggta
     7201 cctttgaaaa aagaagatct agcaaagcat attagtgaac ataagtcgaa tcaacctaaa
     7261 cgtgaaacga cgcaagtacc tattgtaaat gggcctgctc atcatcagca attccaaaag
     7321 ccagaaggta cggtgtacga accaaaacct aaaaagaaat caacacgaaa gattgtgctc
     7381 ttatcattaa tcttttcgtt gttaatgatt gcacttgttt cttttgtggc aatggcaatg
     7441 tttggtaata aatacgaaga gacacctgat gtaatcggga aatctgtaaa agaagcagag
     7501 caaatattca ataaaaacaa cctgaaattg ggtaaaattt ctagaagtta tagtgataaa
     7561 tatcctgaaa atgaaattat taagacaact cccaatacag gtgaacgtgt tgaacgtggt
     7621 gacagtgttg atgttgttat atcaaaaggc cctgaaaagg ttaaaatgcc aaatgtcatt
     7681 ggtttaccta aggaggaagc cttgcagaaa ttaaaatcgt taggtcttaa agatgttacg
     7741 attgaaaaag tatataataa tcaagcgcca aaagaataca ttgcaaatca aagtgtaacc
     7801 gcaaatactg aaatcgctat tcatgattct aatattaaac tatatgaatc tttaggcatt
     7861 aagcaagttt atgtagaaga ctttgaacat aaatccttta gcaaagctaa aaaagcctta
     7921 gaagaaaaag ggtttaaagt tgaaagtaag gaagagtata gtgacgatat tgatgagggt
     7981 gatgtgattt ctcaatctcc taaaggaaaa tcagtagatg aggggtcaac gatttcattt
     8041 gttgtttcta aaggtaaaaa aagcgactca tcagatgtca aaacgacaac tgaatcggta
     8101 gatgtaccat acactggtaa aaatgataag tcacaaaaag ttaaagttta tattaaagat
     8161 aaagataatg acggttcaac tgaaaaaggt agtttcgaca ttactagtga tcaacgtata
     8221 gacattcctt taagaattga aaaaggaaaa acagcaagtt atattgttaa agttgacggt
     8281 aaaactgtag ctgaaaaaga agtcagctat gatgaagttt aaatataatt gtaataagtg
     8341 taccgaggtt tctatttgga agtctcggta ttttttgttg agattgcggt agttttaaaa
     8401 tgctttatga catcatatac aggtgagcat tgtctatcaa ttctgtttca ctcccacaat
     8461 atttatatca tttgaaatga tcatttatat attaattttc cagtctttga tataataaat
     8521 gcagtaaaat taatcgagag gtgccatttt gaagacaggt cgaatagtga aatcaattag
     8581 tggggtatat caagtagacg ttaatggcga acgtttcaat acaaaaccac gaggattatt
     8641 tagaaagaaa aaattttcac cagtagttgg agatatagtg gaatttgatg tacaaaacat
     8701 taatgaaggc tatattcatc aagtgtatga gcgaaaaaat gagttgaaaa gaccacctgt
     8761 aagtaatata gatacactag taattgtaat gagtgctgtc gagccaaatt tttcaacgca
     8821 attattagat cgatttttag ttattgcaca ttcgtatcag ttagatgcga gagttttggt
     8881 gactaaaaaa gataaaacac caattgaaaa gcagcttgaa attaatgagt tgttgaaaat
     8941 atatgaaaat attggctatg agactgaatt tattggaaat gatgatgatc gaaaaaaaat
     9001 tgtagaagct tggccagcag gacttatagt acttagtggt caatcaggtg tcggtaagtc
     9061 cactttctta aatcattatc gtccagaact taatcttgag acaaatgata tatcaaaatc
     9121 attaaatcga ggaaagcata ctacaagaca tgtcgaacta ttcgaacgtc aaaacggtta
     9181 tattgcagac acacctggat tcagtgcttt agattttgat catatagata aagatgaaat
     9241 aaaagattat tttcttgaat taaatcgata tggtgaaaca tgtaagttta gaaattgtaa
     9301 tcatatcaaa gaacctaatt gtaatgttaa gcatcaatta gagataggga atattgcgca
     9361 atttagatac gaccattatt tacaactatt taatgaaatt tcaaatagaa aggttagata
     9421 ttaaatgaca aaactatatc catcattatt atctgttgat tttttggatt tacaacatga
     9481 attaaaacga cttgaagaag caggtgtcga cggagttcat tttgatgtta tggatggtca
     9541 atttgtgcct aatatatcta ttggtttacc aatattagat gcagtgagaa aaggcacaac
     9601 attacctata gacgtacatt tgatgattga aaatccagaa aagtatattg catcatttgc
     9661 agaacatggt gccgatatga tttcaattca tgtcgaatca acgcctcata tccatcgtgc
     9721 tattcaaatg attaaacatt tagataaaaa agctggtgta gtaattaatc ctggtacacc
     9781 aatatcacaa attgaaccta ttttagacat tgttgattat gtactagtga tgacagttaa
     9841 cccagggttt ggtggtcaat catttattga tcaatgcgta gaaaaaatag cgggtcttaa
     9901 tgctattaaa atggaacgtc aattaaactt tgatattgaa gttgatggag gcgtaaatac
     9961 cgatacagcg aaagtttgtg ttgaaaatgg tgctacaatg ttagtaacag gttcattttt
    10021 ctttaaacaa gaggattata aaaaagtcac acaagcattg aaaggttgag tgtatatgca
    10081 tataaattta ttatgttctg atcgacactt gccgcaagat atttgggcca aaagtaatga
    10141 aggtaaatgg ggcggcgttg atagaggtgc tttgatttta ttgaagcatc aaattatccc
    10201 ttttttctca gtgggagact ttgattcagt cagtaaagaa gaacgccaac ttctaacaga
    10261 acagttacaa atcaaaccag ttcaagctga aaaagctgat acggatttag ctttagcggt
    10321 tgataaagct gttgcacttg ggtttgatag tattacaatt tatggtgcaa caggcggacg
    10381 attagatcac ttttttgggg caattcagtt attattgaaa aaagcatatt ataaacatga
    10441 tgttcatata gaagttatcg atcaacaaaa taaaattgaa ttattaccta aaggtcaaca
    10501 tacagttgaa aaagataaga gttatccgta catttcattt ataccgatga ctgatgatgt
    10561 agaactttct ctagcaggtt ttaaatataa tttagctaga caaatgctta atataggttc
    10621 tactttaact atttcaaatg aaattgagtc tttgcaagcg aaagtaactg tacatgatgg
    10681 gttgattttg caaattagaa gtacagattt aaattaagta tattcaaatt tgtgaggatt
    10741 tttaataaag tgacgtttat agatagaatt tataacataa taatagatga atcacgctgt
    10801 aattaatgaa gattatggcg tgatttatta tcgaaaggaa aattgtaggt cctagtacat
    10861 tgatttatgt gccaaaatcg atattgaacc cataagtcca atttgacaga gaaccattat
    10921 taaacgtatt aaccaaatta tattgatagt tcgaatttca ctatgaacca ttatgtattg
    10981 tttggtaaca aaaaaagaac taagaggttg agctcttagt tcttaagtaa atgtgtcctc
    11041 cacataaggt cacatttttt atgtgcaata tatttattaa actctagtta ctttaccaga
    11101 ttttaaagca cgtgcagaaa cccaaacttt tttaggttta ccgtcaacta ggattctaac
    11161 tttttgaagg ttagcgttcc atctacgttt agtagagttt aaagcgtgtg aacgtctgtt
    11221 accagtcgaa gctttacgac ctgttacgaa acattgttta cccatatgag tacctccttt
    11281 aataaatata aatacacata actacttata tacttaacta agatagcata gtttcatttg
    11341 aaaaacaatg aataattttc acataaaagt caaaaatact gagttttgtg atataattgt
    11401 agactgtgaa gttatgtagt atgatatttt agagaaataa gtgaatgaaa catttaaact
    11461 ttttatttaa tgatactaca tctattaaaa gaaaacgcct atagataatc gtcatgagtg
    11521 taaattcagt ttactcaaaa tataataggt gatttaagcg taagtcattc tgataagttg
    11581 tactattgat attttataaa aataatcaat gaaacttaaa gcgtttatga ctacactaag
    11641 tggtaaaatt ttaaaagtga ttagggaaaa cgaataataa actttgaaat ttaggaggga
    11701 caaagatatg acattagaga tttcaaatga ttacggtaaa attgatattt caaacgaagt
    11761 gattgcttcg gttgtaggtg gaaaagccgt tgaatgttat ggtattgtag gtatggcatc
    11821 tagacaacaa gttagagatg gtattgcgga aatactagga catgaaaatt atgctaaagg
    11881 catcaaagta actgaaaata atggcgtagt gaatatagat atgtacatta ttgtaagtta
    11941 cggtgtgaaa atatctgaag ttgccaataa tgtacaatca acagtgaaat atactttgga
    12001 aaaatcactt aatgtatcag taaattcaat caatatatat gtacaaggtg tacgtgtgaa
    12061 taatacaggc aagaaagctt aggaggacaa cttgaaatga ttagcaaaat taatggtaaa
    12121 ttatttgccg atatgattat acaaggggca caaaatttat ctaacaatgc agatttggta
    12181 gattctttga atgtgtatcc agtgccagat ggtgatacag gaacaaatat gaatcttact
    12241 atgacttcag gtcgcgaaga agtagagaat aatttgtcga aaaatatcgg cgaattaggt
    12301 aaaacattct cgaaaggttt actaatgggt gcaagaggta actctggtgt catcttgtca
    12361 caattattca gaggattttg taaaaatatt gaaagtgaat ctgaaattaa ctcaaaattg
    12421 ttagctgaaa gttttcaagc tggtgttgaa acggcatata aagctgttat gaaaccagtt
    12481 gaaggtacaa tacttacagt tgcaaaagat gctgcgcaag ccgcagtaga aaaagcaaat
    12541 aatactgaag attgtataga attaatggag tacattattg taaaagccaa tgaatcactt
    12601 gaaaacacac caaacttatt agctgtactt aaagaagttg gtgttgttga tagtggtggt
    12661 aaaggtttgt tatgcgttta cgaaggattc ttaaaagcgc ttaaaggtga aaaagttgaa
    12721 gccaaagttg caaagataga taaagatgaa tttgtacatg atgaacatga tttccatggt
    12781 gtaattaata ctgaagatat tatttatggc tattgtaccg aaatgatggt tcgttttgga
    12841 aagaataaaa aagcctttga tgaacaagaa ttcaggcaag atatgagtca atttggtgat
    12901 tctttattag tcattaatga tgaagaaatt gtgaaagttc acgtgcatac cgaacaccca
    12961 ggtaaagtgt ttaattatgg tcaacaatat ggtgaattaa ttaaacttaa ggttgaaaat
    13021 atgagagaac agcaccgtga agtgattcga aaagaacagc acacggctaa accgaaaatg
    13081 gaaacggttg aaacagcaat tattactatt tctatgggtg aaggtatttc agagatattt
    13141 aaatcaatgg gtgccacaca tatcattagt ggtggacaaa cgatgaatcc ttctacagaa
    13201 gatatcgtta aagtcattga acaatcaaaa tgtaaacgtg caattatttt accaaataat
    13261 aaaaatatct taatggcaag tgaacaagca gcgagtattg ttgatgcaga agcagttgtt
    13321 attccaacga aatctattcc tcaaggtata agcgcactat tccaatatga tgtggacgca
    13381 acacttgaag aaaataaagc gcaaatggct gattcagtaa ataacgttaa atctggttca
    13441 ttaacgtacg ctgttcgtga tacgaaaatt gatggcgttg agataaaaaa agacgcgttt
    13501 atgggcttga ttgaagataa gattgtaagc agccaaagtg atcaattaac aacggttact
    13561 gagttgttaa atgagatgtt agcagaagat agtgaaatat tgactgtgat tattggtcaa
    13621 gatgcagagc aagaagttac agataacatg ataaactgga tcgaagagca atatccagat
    13681 gtagaagtgg aagttcatga aggtggacaa ccaatttatc aatatttctt ttcagtagaa
    13741 taaaaattta aaataaaaaa ctaccaatga taaatcatca gttggtagtt ttttattttg
    13801 ctattttagt gttattgcgg gttaaaagta tcattctcga gttgctaaca atgtcatgtt
    13861 caacttagtc atgataaaat aaataacata caaaatgata cgtaaaatca aataaaacat
    13921 aggtgattta ttttggctaa agtaaactta atagaaagtc catattctct tttacaatta
    13981 aaaggtatag gtcctaagaa aatagaagca ttgcaacaac taaatattca tacagtggaa
    14041 gatcttgttc tttatttgcc aactagatat gaagataata cagtgattga tttgaatcaa
    14101 gcagaagatc aatctaacgt tacgatagaa ggacaagtat atacagctcc agttgttgca
    14161 ttttttggaa gaaataaatc aaaattaacc gttcatttaa tggtaaataa tattgctgtc
    14221 aaatgtattt ttttcaatca accgtattta aaaaagaaaa tcgaattaaa tcaaactata
    14281 actgttaaag gtaagtggaa tagggttaaa caggaaatta ctggtaatag ggttttcttt
    14341 aattcacaag ggacacaaac tcaagaaaac gcagatgttc aattagaacc agtctatcgt
    14401 attaaggaag gtattaaaca aaagcaaata cgagaccaaa ttagacaagc gttaaatgat
    14461 gtgacaattc atgaatggtt aactgatgaa ctaagagaaa aatataaatt agagaccttg
    14521 gactttactt tgaacacgtt acatcatcca aaaagtaaag aggatttatt acgtgctcgt
    14581 agaacctatg catttactga actgttttta ttcgaattac gtatgcaatg gctaaataga
    14641 ttagaaaagt catctgacga agcaattgaa attgattatg acttagacca agttaaatca
    14701 tttattgatc gtttaccttt tgaactaact gaagcacaga aatccagtgt taatgaaatt
    14761 tttagagatt taaaagcacc aatacgtatg catcgattac ttcaaggtga tgtaggttca
    14821 ggaaaaacag ttgttgctgc aatttgtatg tatgcattaa aaacggctgg ttatcaatca
    14881 gcattgatgg taccaactga aattttagca gagcaacatg ctgaaagttt aatggcttta
    14941 tttggagatt ctatgaacgt tgcattgtta actgggtcag taaaaggtaa gaaacgaaaa
    15001 atacttttag aacaacttga aaatggtacg attgattgtt taattggaac tcatgcattg
    15061 attcaagatg atgtgatttt ccataatgtt ggtttagtaa ttacagatga acaacatcga
    15121 tttggtgtga atcaacgcca gcttttaaga gaaaaaggtg caatgacaaa tgtgttattt
    15181 atgacagcaa ccccgatacc aagaacacta gcaatatcag tttttggtga gatggatgtg
    15241 tcttcaatta aacaattacc aaaaggtcgt aaacctatca ttactacttg ggcaaagcat
    15301 gagcaatacg ataaagtttt gatgcaaatg acttcagagt tgaaaaaagg tcgtcaagca
    15361 tatgtcattt gcccgcttat agaaagttct gagcatctcg aagatgttca aaatgttgtc
    15421 gcattgtacg agtctttaca acagtattat ggtgtttccc gtgtagggtt attgcatggt
    15481 aagttgtctg ccgatgaaaa agatgaggtc atgcaaaagt ttagcaatca tgagatagat
    15541 gttttagttt ctactactgt tgttgaagta ggtgttaatg taccgaatgc aacttttatg
    15601 atgatttatg atgcggatcg ctttggatta tcaactttac atcagttacg cggtcgtgta
    15661 ggtagaagtg accagcaaag ttactgtgtt ttaattgcat cccctaaaac agaaacagga
    15721 attgaaagaa tgacaattat gacacaaaca acggatggat ttgaattgag tgaacgagac
    15781 ttagaaatgc gtggtcctgg agatttcttt ggtgttaaac aaagtggatt gccagatttc
    15841 ttagttgcca atttagttga agattatcgt atgttagaag ttgctcgtga tgaagcagct
    15901 gaacttattc aatctggcgt attctttgaa aatacgtatc aacatttacg tcattttgtt
    15961 gaagaaaatt tattacatcg tagttttgac taattgccat gctgatttgt caatttgagt
    16021 gcaacacttc gttaattgag tgatatgaca cttgaactat ttaaatgtaa agtggtattt
    16081 taacaattta taaattttcg actaaataat agctaaataa tacagttatt tgttgagtcg
    16141 gttaaataga aagtgttatg atatgtgagg aatgtttaag actaggtact aaaaaatgag
    16201 gggtgagacg ttgaaactaa agaaagataa acgtagagaa gcaatcagac aacaaattga
    16261 tagcaatccc ttcatcacag accatgaact aagcgactta tttcaagtga gtatacaaac
    16321 aattcgttta gatcgcactt atttaaacat accagaatta aggaagcgta ttaaattagt
    16381 tgctgaaaag aattatgacc aaataagttc tattgaagaa caagaattta ttggtgattt
    16441 gattcaagtc aatccaaatg ttaaagcgca atcaatttta gatattgcat cggattctgt
    16501 ttttcataaa actggaattg cgcgtggtca tgtgctgttt gctcaggcaa attcattatg
    16561 tgttgcgcta attaagcaac caacagtttt aactcatgag agtagcattc aatttattga
    16621 aaaagtaaaa ttaaatgata cggtaagagc agaagcacga gttgtaaatc aaactgcaaa
    16681 acattattac gtcgaagtaa agtcatatgt taaacataca ttagttttca aaggaaattt
    16741 taaaatgttt tatgataagc gaggataaaa ttatggttaa attagcaatt gatatgatgg
    16801 gtggcgacaa tgcgcctgat atcgtattag aagccgtaca aaaggctgtt gaagacttta
    16861 aagatctaga aattatactt ttcggtgacg aaaaaaagta taatctgaac catgaacgaa
    16921 tcgaatttag acattgttct gaaaagattg aaatggaaga tgagcctgtt agagcgatta
    16981 aacgtaaaaa agatagctca atggtaaaaa tggctgaagc tgtgaaatct ggtgaagcag
    17041 atggatgtgt gtcagcaggt aatactggtg ctttaatgtc agctggttta ttcattgttg
    17101 gacgtattaa aggtgtagct agaccggctt tagtagtaac attgccaacg attgatggaa
    17161 aaggttttgt ctttttagac gttggtgcaa atgctgatgc taaacctgaa cacttattac
    17221 agtatgcgca actaggggat atttatgctc aaaaaattag aggtattgat aatccgaaaa
    17281 tctcattatt aaatatagga accgagccag ctaaaggtaa tagtttaacg aaaaaatcat
    17341 atgagttatt aaatcatgat cattcattga attttgttgg gaatattgaa gcgaagacat
    17401 taatggatgg cgatacagat gttgtagtta ccgatggcta tacagggaac atggtcctta
    17461 aaaatttaga aggtactgca aaatcaatcg gtaaaatgtt aaaagatacg attatgagta
    17521 gtactaaaaa taaattagca ggtgcaatat tgaagaaaga tttagctgaa ttcgctaaaa
    17581 agatggacta ctcagaatac ggtggttccg tattattagg attggaaggt actgtagtta
    17641 aagcacacgg tagttcaaat gctaaagctt tttattctgc aattagacaa gcgaaaatcg
    17701 caggagaaca aaatattgta caaacaatga aagagactgt aggtgaatca aatgagtaaa
    17761 acagcaatta tttttccggg acaaggtgcc caaaaagttg gtatggcaca agatttgttt
    17821 aacaacaatg atcaagcaac tgaaatttta acttcagcag cgaacacatt agactttgat
    17881 attttagaga caatgtttac tgatgaagaa ggtaaattgg gtgaaactga aaacacgcaa
    17941 ccagctttat tgacgcatag ttcggcatta ttagcagcgc taaaaaattt gaatcctgat
    18001 tttactatgg ggcatagttt aggtgaatat tcaagtttag ttgcagctga cgtattatca
    18061 tttgaagatg cagttaaaat tgttagaaaa cgtggtcaat taatggcgca agcatttcct
    18121 actggtgtag gaagcatggc tgcagtattg ggattagatt ttgataaagt cgatgaaatt
    18181 tgtaagtcat tatcatctga tgacaaaata attgaaccag caaacattaa ttgcccaggt
    18241 caaattgttg tttcaggtca caaagcttta attgaagagc tagtagaaaa aggtaaatca
    18301 ttaggtgcaa aacgtgtcat gcctttagca gtatctggac cattccattc atcgctaatg
    18361 aaagtgattg aagaagattt tgcaagttac attaatcaat ttgaatggcg tgatgctaag
    18421 tttcctgtag ttcaaaatgt aaatgcgcaa ggtgaaaccg acaaagaagt aattaaatct
    18481 aatatggtca agcaattata ttcaccagta caattcatta actcaacaga atggctaata
    18541 gaccaaggtg ttgatcattt tattgaaatt ggtcctggaa aagttttatc tggcttaatt
    18601 aaaaaaataa atagagatgt taagttaaca tcaattcaaa ctttagaaga tgtgaaagga
    18661 tggaatgaaa atgactaaga gtgctttagt aacaggtgca tcaagaggaa ttggacgtag
    18721 tattgcgtta caattagcag aagaaggata taatgtagca gtaaactatg caggcatcaa
    18781 agagaaagct gaagcagtag tcgaagaaat caaagctaaa ggtgttgaca gttttgcgat
    18841 tcaagcaaat gttgccgatg ctgatgaagt taaagcaatg attaaagaag tagttagcca
    18901 atttggttct ttagatgttt tagtaaataa tgcaggtatt actcgcgata atttattaat
    18961 gcgtatgaaa gaacaagagt gggatgatgt tattgacaca aacttaaaag gtgtatttaa
    19021 ctgtatccaa aaagcaacac cacaaatgtt aagacaacgt agtggtgcta tcatcaattt
    19081 atcaagtgtt gttggagcag taggtaatcc gggacaagca aactatgttg caacaaaagc
    19141 aggtgttatt ggtttaacta aatctgcggc tcgtgaatta gcatctcgtg gtatcactgt
    19201 aaatgcagtt gcacctggtt ttattgtttc tgatatgaca gatgccttaa gtgatgagct
    19261 taaagaacaa atgttgactc aaattccgtt agcacgtttt ggtcaagaca cagatattgc
    19321 taatacagta gcgttcttag catcagacaa agcaaaatat attacaggtc aaacaatcca
    19381 tgtaaatggt ggaatgtaca tgtaatatat ttgagctaaa gctcaagata aagacgtagt
    19441 aatcaataaa ttgataacag ggatagaggt acgcctgagc taaagctcat tgacgcagtg
    19501 gttgactggt catccgatgg agaattgcct gacctagtca actttgcggg gggaattcta
    19561 agtaacctag ataaggttcc agaatttctc cctaagaaac actaatcaat aaattgataa
    19621 gaagattaga ggaacgcttg agctaaagct catgcataag aaacagtaat caataaattg
    19681 ataactggga tagaggtacg cctgagctaa agctcatgca taagaaacag taatcaataa
    19741 attgataact gtttctaaaa tttctacttg ttttttagaa tttaaaatgg gaaaatataa
    19801 tagtctatgt ataggcattt ttaaaggagg tgaatcgacg tggaaaattt cgataaagta
    19861 aaagatatca tcgttgaccg tttaggtgta gacgctgata aagtaactga agatgcatct
    19921 ttcaaagatg atttaggcgc tgactcactt gatatcgctg aattagtaat ggaattagaa
    19981 gacgagtttg gtactgaaat tcctgatgaa gaagctgaaa aaatcaacac tgttggtgat
    20041 gctgttaaat ttattaacag tcttgaaaaa taataaatct tacatctggg tcgtcagtat
    20101 tgtcgactca gtttttttct ttaattatca atagttttaa cgtaaaatta aagatgattc
    20161 aagagcaaca cataaaggag ataaaataat gtctaaacaa aagaaaagtg agatagttaa
    20221 tcgttttaga aagcgctttg atactaaaat gacagagtta ggctttactt atcaaaatat
    20281 tgatttatac caacaagcat tttcgcattc gagttttatt aatgatttta atatgaatcg
    20341 tttagaccat aatgagcgtt tagagttttt gggtgatgcg gtattagaat tgacggtttc
    20401 acgatattta tttgataaac atcccaactt gccagaaggg aatttaacaa aaatgcgtgc
    20461 cactattgta tgtgagccct cacttgtaat atttgcgaat aaaattggat tgaacgaaat
    20521 gattttactt ggtaaaggtg aagagaaaac agggggacgt acaagaccat cattaatatc
    20581 agatgcattc gaagcattta ttggggcatt gtatttggat caaggactag atatagtttg
    20641 gaaatttgct gagaaagtta ttttcccaca tgtagaacaa aatgagttat taggagtggt
    20701 agattttaaa acacaattcc aagaatatgt gcaccagcaa aataaaggtg atgtaaccta
    20761 taatttaata aaagaagagg gaccggcaca tcatcgtcta ttcacttcag aagttattct
    20821 gcaaggggaa gcaatagctg aaggtaaagg gaaaacgaaa aaagaatcag aacaacgtgc
    20881 tgctgaaagt gcctataagc aattaaaaca aattaaatag aaatttatat gatacgacat
    20941 ataggtgttc gatttaggat ttaaggaaga atttttaata ttttatggaa caacttcgaa
    21001 atttaatata caaatattaa aatatcgtat acatgtgttc tttaaaattg tgataaggag
    21061 tttaggatgg tttatttaaa atcaatagat gccattggat ttaagtcttt tgcagatcaa
    21121 accaatgttc aattcgataa aggtgtaact gcaattgttg gtccaaatgg aagcggtaaa
    21181 agtaatatta cagatgctat taaatgggtg ttgggtgaac aatcggctaa atcattacgt
    21241 ggctcaaaaa tggaagatat tatcttctca ggtgcagaac atcgcaaagc tcaaaattat
    21301 gctgaagtac agttaagatt agataatcat tctaaaaagc tcagtgttga tgaaaacgaa
    21361 gttattgtaa caagaagatt gtatcgaagt ggtgaaagtg agtactacat aaataatgac
    21421 cgtgcaagat taaaagatat tgccgattta tttttagatt ctggattggg aaaagaagca
    21481 tatagcatta tctcgcaagg tagagttgat gaaatactaa atgctaaacc aattgataga
    21541 cgtcaaatta ttgaagaatc ggctggtgta cttaaatata aaaaacgtaa agctgaatca
    21601 ttaaataaac ttgaccaaac agaagataat ttaacgagag tagaagacat tttatatgat
    21661 ttggaaggtc gtgtagaacc tctaaaagag gaggcagcta tagctaaaga atataagaca
    21721 ctttcacacc aaatgaaaca tagtgacatt gtagttacag tgcacgatat tgatcaatat
    21781 acaaatgaca atagacaatt agatcaacgt ttaaatgatt tacaaggtca acaagcaaat
    21841 aaagaagctg acaagcaacg tttaagccaa caaattcaac aatataaagg taaacgtcat
    21901 caacttgata atgatgttga atcgcttaat tatcaattag taaaagctac ggaagccttt
    21961 gaaaaatata cgggacaatt aaatgtttta gaagaacgta agaaaaatca atctgaaaca
    22021 aatgcacgat atgaagaaga acaagaaaat ttaatggagc ttttagaaaa tatatcaaat
    22081 gagatttctg aagctcaaga tacttataag tctctgaaaa gtaaacaaaa agaactcaat
    22141 gctgtcattc gtgaacttga agaacaacta tatgtttcag acgaagcaca tgatgaaaaa
    22201 ttggaagaaa ttaaaaacga atactataca ttaatgtcag agcaatcaga tgttaacaat
    22261 gatattcgtt ttttaaagca tactatagaa gagaatgagg ctaaaaaatc aagactagat
    22321 tctcgattag ttgaagtttt tgagcaattg aaagatattc agggtcaaat aaaaacgaca
    22381 aaaaaagaat atcaacagac caacaaagaa ctttctgctg tagataaaga aattaaaaat
    22441 atagaaaaag atctcactga tacaaaaaaa gcacaaaatg aatacgaaga gaaattgtat
    22501 caagcatatc gatataccga aaaaatgaaa acacgtattg atagtttggc aacgcaagag
    22561 gaagaatata cttatttttt caatggcgtc aaacatattt tgaaagctaa aaataaagaa
    22621 ttaaagggta ttcatggtgc agttgcggaa attattgatg tgccatctaa attaactcag
    22681 gcaattgaaa cagcattagg tgcttcatta caacatgtca ttgtagattc agaaaaagat
    22741 ggacgccagg ctattcaatt tttaaaagaa cgtaatttag gtcgtgcgac gtttttacca
    22801 ttaaatgtta tacagagtag agtggtagcg actgatatta aatctattgc taaagaggca
    22861 aacggattta ttagtatcgc ttcggaagca gttaaagtag caccagaata tcaaaatatt
    22921 atcgggaatt tattaggtaa tacgattatc gttgatcatt taaagcatgc aaatgaattg
    22981 gcacgtgcga ttaaatatcg aactcgtatt gttactttgg aaggtgatat tgtaaatcct
    23041 ggtggttcta tgactggtgg tggcgctcgt aagtcaaaaa gtattctgtc tcaaaaagac
    23101 gagttgacaa caatgagaca ccaattagaa gattacttgc gtcaaacaga atcatttgaa
    23161 caacaattta aagagttgaa gataaaaagt gatcaattaa gtgaactgta ttttgaaaaa
    23221 agtcaaaagc ataatacact taaagagcaa gtgcatcatt ttgaaatgga gctcgataga
    23281 ttaactacac aagaaacaca aataaaaaat gatcatgaag aattcgaatt tgaaaaaaat
    23341 gatggttata cgagtgacaa aagtcgacaa actttgagtg aaaaagaaac tcatctagaa
    23401 agtattaaag catctttaaa acgactagaa gatgaaattg aacgctacac aaaactttct
    23461 aaagaaggta aggaaagcgt tactaaaaca caacaaacct tacatcagaa acaatctgat
    23521 cttgctgtgg ttaaagagcg tattaaaaca caacaacaga caatagatcg attaaataat
    23581 caaaatcaac aaactaaaca tcaattaaaa gatgttaaag aaaaaattgc attctttaat
    23641 tcggatgaag tgatgggcga acaagctttt caaaatatta aagatcaaat taatggtcaa
    23701 caagaaacga gaacacgctt atctgatgaa ttagataaat tgaaacaaca acgtattgag
    23761 ttgaatgaac aaatcgatgc gcaagaagct aaactacaag tttgtcacca agatatttta
    23821 gctatcgaaa atcactacca agatattaaa gctgaacaat caaagctaga tgtattaatt
    23881 catcatgcga tagatcattt aaatgatgaa tatcaattga ctgttgaacg tgcgaaatct
    23941 gaatatacga gtgatgaatc gattgacgca ttacgtaaaa aagttaagtt aatgaagatg
    24001 tcgattgatg aactaggtcc tgtaaactta aatgcaattg aacaatttga agagttaaat
    24061 gaacgttata catttttaag tgaacaacgt acagatcttc gtaaagctaa agaaacatta
    24121 gagcaaatta taagtgaaat ggatcaagag gttactgaaa gatttaaaga aactttccat
    24181 gctattcaag gacattttac agctgtgttc aaacaattgt ttggtggagg cgatgcagaa
    24241 ttgcaattaa ctgaagccga ttatttaaca gctggtattg atattgtggt acaaccaccg
    24301 ggtaaaaagt tgcaacattt atcgttacta agtggtggtg agcgtgcatt aactgctatt
    24361 gctttactat ttgcaatttt aaaagtaaga tctgcacctt ttgttatatt agatgaggtt
    24421 gaagctgcat tagatgaagc gaatgttatt agatacgcaa aatatttaaa tgagttatca
    24481 gacgaaacac aattcattgt tattacacac cgtaaaggaa caatggaatt tgctgatagg
    24541 ttatacggtg tgacaatgca agaatcaggt gttactaaac ttgtgagtgt gaatttaaat
    24601 acaatagatg atgtgttgaa ggaggagcaa taatgagctt ttttaaacgc ttaaaagata
    24661 aatttgcaac aaataaagaa aatgaagaag ttaaatcctt aacagaagaa caaggtcaag
    24721 acaaattaga agatacacat tctgaaggtt caacgcagga cgtaaatgat ttagcagaaa
    24781 atgctgaagt gaaaaagaag ccacgcaagt taagtgaagc ggattttgat gacgatggct
    24841 taatatcaat tgaagatttt gaagaaattg aagctcaaaa aatgggtgct aaatttaagg
    24901 caggactcga aaaatctcgt caaaatttcc aagaacaatt aaataatttg atagcgagat
    24961 atcgtaaagt agatgaagac ttttttgaag ctttagaaga aatgttaatc actgcagacg
    25021 tcggttttaa tactgtgatg acgttaactg aagaattacg tatggaagca caacgacgta
    25081 atattcaaga tactgaagat ttgcgtgaag tcattgttga aaaaatcgta gagatttacc
    25141 atcaagaaga tgataattca gaagctatga acttagaaga tggtcgttta aatgtcattt
    25201 taatggttgg tgtgaatggt gttggtaaaa caacaacaat tggaaaatta gcttaccgat
    25261 ataaaatgga aggtaaaaaa gtaatgttag ctgcgggcga tacttttaga gcgggtgcta
    25321 ttgatcaatt gaaagtttgg ggcgaacgtg ttggtgtaga tgtaattagc caaagtgaag
    25381 gttctgatcc agctgctgtt atgtatgatg cgattaatgc cgctaaaaac aaaggtgttg
    25441 atattttaat ctgtgatacc gctggacgtt tacaaaataa aacaaatcta atgcaagaat
    25501 tagaaaaagt taagcgtgta attaatcgag cagtgccaga tgcgcctcat gaagcattac
    25561 tatgtttaga tgctacaact ggtcagaatg cgttgtcaca agctagaaac tttaaagaag
    25621 taacaaatgt tacaggtatt gtattaacga aattagatgg tacagccaaa ggtggtatcg
    25681 tattagccat tcgtaatgaa ttgcacattc cagttaaata tgtaggttta ggtgagcaat
    25741 tagatgactt acaaccattt aaccctgaaa gttatgtcta cggcttattc gctgatatga
    25801 ttgaacaaaa tgaagaaata acaacagttg aaaatgatca aattgtaaca gaagaaaagg
    25861 acgataatca tggggcaaaa tgatttagtt aaaacgttac gaatgaatta tttgtttgat
    25921 ttttatcaat ccttattgac gaataaacaa cgtaattatt tggaattatt ttatctcgaa
    25981 gattattctt tgagtgaaat cgcagatact tttaatgtga gtagacaagc agtttatgat
    26041 aatataagaa gaactggcga tttagttgaa gattatgaaa agaaattgga attataccag
    26101 aaatttgagc aacgccgaga aatatatgat gaaatgaaac aacatttaag taatccagaa
    26161 caaatacaac gttatattca acaattagaa gacttagaat agatataaat tgagggagga
    26221 catcgatatg gcatttgaag gcttatcaga acgcctgcaa gcgacgatgc aaaaaatgcg
    26281 tggtaagggt aaacttactg aagctgatat aaagataatg atgcgtgaag taagattagc
    26341 gttacttgag gctgacgtaa actttaaagt ggtaaaagaa tttattaaaa cagtatcaga
    26401 acgcgcatta ggttccgatg taatgcaatc attaacacct gggcaacaag ttattaaaat
    26461 agttcaagat gaattaacga agttgatggg tggagaaaat tcatcgatta atatgtcaaa
    26521 taaaccacct actgttgtta tgatggttgg tttacaaggt gctggtaaaa caacaactgc
    26581 aggtaaatta gcattattga tgcgtaaaaa atacaacaaa aaacctatgt tagttgcagc
    26641 agatatttat cgtccagcag cgataaatca attacaaaca gtagggaaac aaattgatat
    26701 tcctgtatac agtgaagggg atcaagtaaa gccacaacaa attgtaacta atgcattaaa
    26761 acatgctaaa gaagaacatt tagactttgt aatcattgat acagcaggtc gattacacat
    26821 cgatgaagca ttgatgaacg aattaaaaga agtaaaagac attgctaaac caaacgaaat
    26881 tatgttagtt gtcgattcaa tgacgggtca agatgctgtc aatgttgcag aatcttttga
    26941 cgatcaactt gatgtcacag gtgttacctt aactaaatta gatggtgata cacgtggtgg
    27001 tgcagcttta tctattcgtt cggtgacaca aaaaccaatt aaatttgttg gtatgagtga
    27061 aaagttagat ggtttagagc tattccatcc tgaacgtatg gcatcacgta ttttaggtat
    27121 gggtgatgtg ttaagtttaa ttgaaaaagc gcaacaagat gtggatcaag aaaaagcaaa
    27181 agatttagag aaaaagatgc gtgaatcatc atttacttta gatgattttt tagaacagct
    27241 tgatcaggtg aaaaatttag gaccactgga tgatattatg aaaatgattc caggtatgaa
    27301 taaaatgaaa ggtctagata agcttaatat gagtgaaaag caaattgatc atattaaagc
    27361 gattatccag tcaatgacgc cggctgaaag aaacaatcca gacacattga atgtatcacg
    27421 taaaaagcgt attgctaaag gttctggtcg ttcattacaa gaagtcaatc gtttgatgaa
    27481 acaatttaac gatatgaaga aaatgatgaa acaattcact ggtggcggta aaggtaaaaa
    27541 aggtaaacgc aatcaaatgc aaaatatgtt aaaaggtatg aacttaccat tttaatgttt
    27601 aatttaacac gctgattttt gttgcaatga gatgtgcatc ccgaaagtta tactaaagaa
    27661 tataacttta tggggtgcat atttttagat acacaataat aattaaaaac tgaaattgct
    27721 gatttgctag aacatgaggt tattgttgct aatattaata agttatattg gtggaacatg
    27781 tgcgttagaa gtggtaccat tcatgtcctt acgagataaa ttaacttaac acgtatgtgg
    27841 tgaaggttaa tatgaatttt tataaactat taacagtcta atttagtaat cacatagtta
    27901 tttttgtaag aaaaaggttc aataattttc ctggtaaaga aaaaactctt tacaaacatt
    27961 cacacacctg ttaatattat ttcttgtaga aaataaaaat taaaacatga cttaaaggag
    28021 attttataaa tggcagttaa aattcgttta acacgtttag gttcaaaaag aaatccattc
    28081 tatcgtatcg tagtagcaga tgctcgttct ccacgtgacg gacgtatcat cgaacaaatc
    28141 ggtacttata acccaacgag cgctaatgct ccagaaatta aagttgacga agcgttagct
    28201 ttaaaatggt taaatgatgg tgcgaaacca actgatacag ttcacaatat cttatcaaaa
    28261 gaaggtatta tgaaaaaatt tgacgaacaa aagaaagcta agtaatttag cgtaaaattg
    28321 ttctaacaat aagaataact cgtttacact gacagttatt actcaatgat acgttgggaa
    28381 tatcacatgt tagtaatata gaacgtattg ggtaccataa tggtgccctt tttctttgaa
    28441 taattttcaa ttaaaataga agtgttcaaa gcatagagtt ggaggtaata gaatgagagt
    28501 tgaagttggt caaattgtta acacacatgg tattaaaggt gaaattaaag taaaatccaa
    28561 ttcagacttt acagacgttc gttttcaacc cggtcaagtg ctgacagttg tgcataacaa
    28621 taacgacctt gaatatactg ttaagtcaca tagagtgcat aaagggcttc atatgcttac
    28681 atttgaaggt attaataata ttaatgatat tgagcattta aaagggagtt ctatttatca
    28741 agagcgtgat catgaagata tcgtacttga ggaaaatgaa ttttattatt cagatattat
    28801 aggatgtaca gtttttgatg atcaagaaac accaataggt cgtgtaatta atatctttga
    28861 aacaggtgca aatgatgtgt gggtgattaa aggatctaaa gaatatttga ttccttatat
    28921 tgctgatgtt gtaaaagaag tggatgttga aaataaaaaa attatcatca cgccaatgga
    28981 aggattgttg gattaatgaa aattgattat ttaactttat ttcctgaaat gtttgatggt
    29041 gttttaaatc attcaattat gaaacgtgcc caagaaaaca ataaattaca aatcaatacg
    29101 gttaatttta gagattatgc aattaacaag cacaaccagg tagatgatta tccgtatggt
    29161 ggcggacaag gtatggtgtt aaagcctgaa cctgttttta atgcgatgga agacttagat
    29221 gtcacagaac aaacacgcgt tattttaatg tgtccacaag gcgagccatt ttcacatcag
    29281 aaagctgttg aattaagcaa ggctgaccac atcgttttca tatgcggaca ttatgaaggt
    29341 tacgatgaac gtatccgaac acatcttgtc acagatgaaa tatcaatggg tgactatgtt
    29401 ttaacaggtg gagaattgcc agcgatgacc atgactgatg ctattgttag actgattcca
    29461 ggtgttttag gtaatgaaca gtcacatcaa gacgattcat tttcagatgg gttattagag
    29521 tttccgcaat atacacgtcc gcgtgaattt aaaggtctaa cagttccgga tgttttattg
    29581 tctggaaatc atgccaatat tgatgcatgg agacatgagc aaaagttgat ccgcacatat
    29641 aataaaagac ctgacttaat tgaaaaatat ccattaacta atgcagataa gcaaatatta
    29701 gaaagatata aaataggatt gaaaaaaggt tagtattgtg ctaacataat ctgagtgtgg
    29761 aaacacaaaa atcactatga tccgctgcta tatatttgtc gaggcaagaa cataggttga
    29821 agaggagaat ttataatgac aaatcacaaa ttaatcgaag cagtaactaa atcacaatta
    29881 cgtacagact taccaagttt ccgtcctggt gatactttac gtgtacacgt acgtatcatt
    29941 gagggtactc gtgagcgtat ccaagtattc gaaggcgttg taattaaacg tcgtggcggt
    30001 ggcgtttctg aaacgtttac agttcgtaaa atttcatcag gtgttggcgt ggaacgtaca
    30061 ttcccattac acacaccaaa aattgaaaaa atcgaagtta aacgtcgtgg taaagtacgt
    30121 cgtgctaaat tatattactt acgtagttta cgtggtaaag ctgctagaat ccaagaaatt
    30181 cgttaatcag catttaaaca aagctatgta tgagtcatat tcgactcaaa caacaaagcc
    30241 atctaggtca cttttatgga gtgatataga tggctttttt tgctgtttag ttaatgtaaa
    30301 gttgataatg taattgtttt tttatttatt cataacgtgt ttgctcaaaa tggttatata
    30361 aacaaaaatc tactaagtgc cattgaaaag gacttagtag atttattaaa tatatgcgta
    30421 gccacattat ttttgtctta cccatctcgt gaaaataata ctacatataa tgccaaatat
    30481 agtaattgtt ataagtaaat aatagtatgg tggggtatag ctcaattgaa tctttgttat
    30541 atttttaggt gctttaatgc cggtcataac accatttact tgttcaactt taagactttg
    30601 atcacctgat gtcgctttca taccttgatt atatgctgtt ggcaaaacaa tatacccaga
    30661 tgaattttta tttttagtaa tagtataacc ttgctttgtc ttactaactt tgacagcctc
    30721 taatgaattt gaagtgtctt taagcgtggt ataatcttcg ccgtatatcc cttttaaatt
    30781 tacacgatac ttacctttag gcaacgataa tttaattgca tctgaagatt taatacgtat
    30841 cgttacaggt gttacaaaac gacggtattt atatgtgagt ttgtttcttt ctagtgtata
    30901 ttcattaact ttaacataat gagctttatc cggcgaaagt aattctaaat ccatttcaaa
    30961 atacaaatct ttaaattgat tagaaactga ttttggcaac tgtacagtta gaccaccatt
    31021 attttgttta acttgtaata aatgttttga aggagattgc caggctgcac tatttaattt
    31081 aattgttgaa tctgatagta aatttttatt ggctttaaaa tgtgtattta catctttagt
    31141 attgttagaa acaatccctt gcaacattgc ttgttcttta tctaatggag attttaattc
    31201 tttattggaa aagaccttat ttgtaatatg tgcacttgga taatggatgg tatttttaga
    31261 atgaatccaa cgaactttat tgtctttgtg ttcagagtta attttaaatc catatggtaa
    31321 gttgtaatca tgatttactc taattcgatc atttacattc caaagcgata gtaaattttg
    31381 acgattgcca agtaatctat aagtgctgtt tttatcgatt ggcatattaa tttggagtgt
    31441 cttgtcataa tattttaaaa tgtctccatt aaaaatacta gaatataatg aaatgccatt
    31501 ataatgatat ataaatggtg aatttaatgc atagtctgac atataatcaa tgcgattaaa
    31561 tgggcctgtt gcattttgat ttatcttttt tataagctgg tttacatagt tactatgata
    31621 atcatgttgt ttcaacgttg atattgattg ttgataaggt ttgattgcca tatttttgtt
    31681 gttatctaaa atgacgattt gttgaatcat aacgattaat actattaata caacggttaa
    31741 ttttttataa cgccataaac taaattttaa aataacggca agcaccatta gcaggataat
    31801 acctactata agtacgagtg ggtgtgtcgg tgatagtaat acataaagta atgcgatgat
    31861 gcttactggt attgttctga ttaaataata tttcatattt aatgttgata aatgctgaat
    31921 aaacaatccg caaagagcac ttgatgatag tgctaagata tacacccaac gcctttctgg
    31981 aaatgaaaaa ccattaaaag cactgtcgaa atactgtgat aatgaaccaa taaataatat
    32041 ccatgttact attgcgaaaa gtctataaaa gtaaaaacga tacagtttga atgacaataa
    32101 tgcaacgata gtaagaattg aaatcgtaat ataaaatcca tcgctaaaga aaaaataatg
    32161 ataatcaagt ggtgtcaaaa acggtatatc aacattggga ttttgctttc tgtcattttc
    32221 caaaaacgca gaaatgccag tgaataaacc aaatacactt gataacacac tcaaaactgc
    32281 agcagatatg acgcaaatta atttttgtgt tctagagaca atgtcatatt tgtaagtgaa
    32341 aatgagtcga tataaatagt agcaacctat aataatagct tgataataac tgaaataaaa
    32401 attgctaaat agtgttaagg ctatcgcaac aatgaatata ccgattttgc gttgttgaaa
    32461 atatctttcc aaaccaagaa tcgataatgg taataaatat aataaatttc cataaaatga
    32521 ccaagtaaaa ttaaagtata taacgacagt tgacatgccg tataaaatcg tagcgatcat
    32581 atttgttgag cgtttaaagt gtaatatttt aaataagtag aaggtcacga caaatgttat
    32641 gatagctcgt atcatggcca taataagttg gtttgtcggc caaaaatgta ttgttgtcgg
    32701 attaaatata ccaaccgttt ctcctatttt aatgaataga aaatttagcc acattaaagg
    32761 tgacagcgaa taataatatg atagtccttt catataatcg ccacctaatc caaacgatgc
    32821 atcatataaa ctagaaaaac tacttagatg ttcatacaaa tacatttgaa atggcatcat
    32881 ttgacggaat ccatctccag ccccactaaa aacagtacca ttcacaatat aatcatagat
    32941 atgagtagaa aataaaataa gcgttaatat tacactaatg aaagttataa caaagaattg
    33001 tttgacgttt gaatttagcc acttttttaa cacaacatta tcctcaactt tcaaatttaa
    33061 aattaagttt aactgaaact aaagttaatg aggttcttga taggtaaaga cgaagatgac
    33121 tgtggaacag ataccttatc atagttactt aaactttgga tcattttcag tttatcatta
    33181 aacaaatata ttgaataata aaaatgtcat actgataaag atgaatgtca cttaataagt
    33241 aacttagatt tattaaatga aaatttttaa ttagagaaaa cttggaataa tcacttatac
    33301 ctgaatctaa agcattgtta agaagtgtga caatgttaaa ataaatatag ttgaattaat
    33361 gaatttgttc tataattaac aggttataga ttttaataat gagaaaagaa ttgacgaaag
    33421 taaggtgaat tgaatggtta ttcaatggta tccaggacat atggcgaaag ccaaaagaga
    33481 agtaagtgaa caattaaaaa aagtagatgt agtgtttgaa ctagtagatg caagaattcc
    33541 atatagttca agaaacccta tgatagatga agttattaac caaaaaccac gtgctgttat
    33601 attaaataaa aaagatatgt ctaatttaaa tgagatgtca aaatgggaac aattttttat
    33661 tgataaagga tactatcctg tatcagtgga tgctaagcac ggtaaaaatt taaagaaagt
    33721 ggaagctgca gcaattaagg cgactgctga aaaatttgaa cgcgaaaaag caaaaggact
    33781 taaaccaaga gcgattagag caatgattgt tggaattcca aatgttggta agtccacatt
    33841 aataaataaa ctggcaaagc gtagtattgc acagactggt aataaaccag gtgtgaccaa
    33901 acaacaacaa tggattaaag ttggtaatgc attacaacta ttagatacac cagggattct
    33961 ttggcctaaa tttgaagatg aagaagtcgg taagaagttg agtttaacag gcgcgattaa
    34021 agatagtatt gtgcacttag atgaagttgc catctatggt ctgaactttt taattcaaaa
    34081 tgatttagcg cgcttaaaag cacattataa aatcgaagtt cctgaagatg cagaaatcat
    34141 agcgtggttt gatgcgatag ggaaaaaacg tggcttaatt cgacgtggta atgaaattga
    34201 ttacgaagca gtcattgaac tgattattta tgatattcga aatgctaaaa taggaaatta
    34261 ttgttttgat atttttaaag atatgactga ggaattagca aatgacgcta acaattaaag
    34321 aagtaacgca gttgattaat gcggttaata caatagaaga attagaaaat catgaatgct
    34381 ttttagatga gcgaaaaggt gtacaaaatg ccatagccag acgcagaaaa gcgttagaac
    34441 aagaacaagc tttaaaagaa aagtatgctg aaatgactta ctttgaaaat gaaatattaa
    34501 aagagcatcc taatgctatt atttgtggta ttgacgaagt tggaagagga cctttagcag
    34561 gtccagtcgt tgcatgcgca acaattttaa attcaaatca caattatttg ggccttgatg
    34621 actcgaaaaa agtacctgtt acgaaacgtc tagaattaaa tgaagcacta aaaaatgaag
    34681 ttactgcttt tgcatatggt atcgctacag ctgaagaaat agatgaattt aatatttata
    34741 aagctactca aatcgccatg cagcgagcta ttgatggatt atcagtacaa ccaacgcatt
    34801 tattgataga cgcgatgacg cttgataatg cactgactca agtatcttta atcaagggtg
    34861 atgcaagaag tgtatctatt gcagcggcaa gtatcatggc aaaggttttt cgtgatgatt
    34921 atatgacaca gttatctaaa gattatcctg aatatggttt tgaaaaaaac gcgggttacg
    34981 gtaccaaaca acatttacta gcaatcgatg atattggcat tatgaaagag catagaaaaa
    35041 gctttgaacc tataaaatcg ttactgtaaa tcgtaaaatt caattaaatg ataaaaaagt
    35101 agcatttaag tttacaatag cgcttacatt ttttataatt gtaagggaac ttaacctaag
    35161 taacaggagg atggaagatg aatatccacg agtatcaagg taaagaaata tttcgttcaa
    35221 tgggcgttgc agttccagaa ggacgagtag catttactgc tgaagaagcg gtggagaaag
    35281 caaaagaatt aaattcagat gtttatgttg taaaagcaca aattcatgct ggaggtagag
    35341 gtaaagcagg cggagtaaaa attgctaaat ctttatcaga ggtagaaaca tatgcaaaag
    35401 aattattagg gaaaactttg gtgacacatc aaactggtcc agaaggtaaa gaaattaagc
    35461 gtttatatat cgaagaaggt tgtgctattc aaaaagaata ttacgttgga ttcgttattg
    35521 atcgtgcgac tgaccaagta acattgatgg cgtctgaaga agggggcact gagattgaag
    35581 aagttgctgc gaagactcct gaaaagatct tcaaagaaac tattgatcca gtaatcggac
    35641 tttcaccatt ccaagcaaga cgaattgcgt ttaatattaa tattcctaaa aaatctgtta
    35701 acaaagctgc taaattctta ttagcacttt ataatgtatt cattgaaaaa gattgttcaa
    35761 tcgtagaaat caacccatta gttacaacag ctgatggtga tgtattggca ttagatgcta
    35821 aaattaattt tgatgataat gcattattca gacataaaga tgttgtagaa ttacgtgatt
    35881 tagaagaaga agatccgaaa gagattgaag cgtctaaaca tgatttatca tacattgcat
    35941 tagatggtga catcggatgt atggttaatg gtgcaggttt agccatggca acaatggata
    36001 cgattaatca tttcggtgga aacccagcca atttcttaga tgcaggcgga agcgctacta
    36061 gagaaaaagt aactgaagca tttaaaatca ttttaggtga tgaaaatgtt aaaggtattt
    36121 ttgtaaacat tttcggtggc attatgaaat gtgatgttat cgcagaaggt atcgttgaag
    36181 ctgtaaaaga agtagattta actttaccac tagttgtacg cttagaaggt acaaatgttg
    36241 agttaggtaa aaaaatctta aaagactcag gattagcaat tgaaccagca gcaacaatgg
    36301 ctgaaggtgc acaaaaaatt gttaaactag tcaaagaagc ataaggaaag gatgggagca
    36361 ctaagatgag tgtatttata gataagaata ctaaagtaat ggtacaaggt attacagggt
    36421 ctactgccct tttccataca aaacaaatgc ttgattatgg tacgaaaata gtagcaggtg
    36481 tgacgcctgg taaaggtggt caagttgttg aaggcgttcc tgttttcaac actgttgaag
    36541 aagctaaaaa tgaaaccggg gcaacggttt cagtcattta cgttccagca ccatttgctg
    36601 cagactcaat tttagaagca gctgatgcag acttagatat ggttatttgt atcactgaac
    36661 atattcctgt attagacatg gttaaagtta aacgctactt acaaggtaga aaaacacgtt
    36721 tagttggtcc gaactgtcca ggtgtgatta cagcagatga atgtaaaatt ggtattatgc
    36781 ctggctatat tcacaaaaaa ggtcatgttg gtgtagtatc acgttcaggt acattaacat
    36841 atgaagcagt gcaccaattg actgaagaag gtattggtca aactacagct gttggtattg
    36901 gtggagaccc agtaaatggc acaaacttta ttgatgtttt aaaagcattc aatgaagatg
    36961 acgaaacgaa agcagttgtt atgattggtg aaatcggtgg tacggctgaa gaagaagctg
    37021 ctgaatggat taaagcgaat atgacaaaac cagttgtagg ctttatcggt ggacaaacag
    37081 cacctcctgg aaaacgtatg ggacatgctg gtgcaatcat ttcaggtggt aaaggtactg
    37141 ctgaagagaa aattaaaaca ttaaatagtt gtggtgtgaa aacagcggca acaccttcag
    37201 aaattggttc aacattaatt gaagctgcta aagaagcagg aatttatgaa tcattattaa
    37261 ctgttaataa ataaagttaa aagatgatat aaatggctat agcccattcc atactttatt
    37321 aaagtatcgg aaatgggcta tttgtcgtgc gatgaatttt agtacacttt tcatattttg
    37381 gaaaggcaag ttaattattt tacctccttc aatagctttc taaaacaaag tgaattttta
    37441 ttataatata tagtgcgcta tgttataata tttatatatt attgcaagga gtgtttcatc
    37501 atgaataaac aacaaagtaa agtacgctat tcaattagaa aagttagtat tggaattttg
    37561 tcaatttcaa ttggtatgtt tttggcattg ggtatgtcga acaaagcata tgcagatgaa
    37621 attgataaat ctaaagattt tacaagaggg tatgagcaaa atgtattcgc gaaatcagag
    37681 ttaaatgcta ataaaaatac gacaaaagac aaaataaaaa atgaaggtgt tgttaaaaca
    37741 tcggacacaa gtttaaagtt agacaacaaa tcagcaattt caaatggaaa tgaaattaat
    37801 caagatataa agatttcaaa tactccgaaa aactcaagcc aaggtaacaa tctagttgtt
    37861 aataacaatg aacctactaa agaaattaaa attgcaaact tggaagctca aaattctaat
    37921 cagaagaaaa cgaataaagt tactaataat tactttggtt actacagttt tagagaagct
    37981 ccaaaaacac aaatctatac tgtaaaaaaa ggagacacac ttagtgctat agcgttaaaa
    38041 tacaaaacta cagtttcaaa tattcaaaat acaaataata tagcaaatcc taatttaata
    38101 tttattggtc aaaaattaaa agtgccaatg acaccattag tagaaccaaa accaaataca
    38161 gtgtcttcaa ataataaaag taatagtaat agcagtacat taaattattt gaaaacatta
    38221 gagaatagag gatgggattt cgacggtagt tatggatggc aatgtttcga tttagtcaat
    38281 gtatattgga atcatcttta tggtcatgga ttaaaaggat atggagctaa agatatacca
    38341 tatgcaaata attttaatag tgaagctaaa atttatcaca acacaccaac tttcaaagct
    38401 gaacctgggg acttagtggt ttttagtgga agatttggtg gaggatatgg tcatacagct
    38461 attgttttaa atggtgatta tgatggaaaa ttaatgaagt tccaaagttt agatcaaaac
    38521 tggaataatg gtggatggcg taaatcagag gttgcacata aagttgttca taattatgaa
    38581 aatgatatga tttttattag accatttaaa aaagcataat ttaaatcaaa ggcaggacat
    38641 tgaaatatga aatttacaac tttaagtgaa gaagaattta ccaactacac caaaaaacac
    38701 ttcaaacatt atacacagtc tatagaatta tataattata gaaataaaat aaatcatgaa
    38761 gcacatattg tgggagtgaa gaatgataaa aatgaagtta tagctgcatg tttattaaca
    38821 gaagcacgta tttttaaatt ctacaaatat ttctactctc atagaggccc tttacttgat
    38881 tatttcgatg ctaaattagt ttgttacttt tttaaagaat tatctaaatt catttataaa
    38941 aatagaggag tatttattct tgttgatcca tatttaatag agaatttaag agatgcaaat
    39001 ggtagggtaa taaagaatta taataattca gtgatagtaa agatgctagg gaaaattggg
    39061 tatctccatc aaggttatac aacaggatat tcaaataaaa gtcaaattag gtggatttct
    39121 gtattggatt taaaagataa agatgagaat caacttttaa aagaaatgga ataccaaact
    39181 agaagaaata taaaaaagac tattgagatt ggtgttaagg ttgaagattt atctattgaa
    39241 gaaacaaatc gattttataa attgtttcaa atggctgaag aaaaacatgg ttttcatttc
    39301 atgaatgaag attattttaa acaaatgcaa gaaatatata aaggtaaggc aatgttaaag
    39361 atagcttgta tagatcttaa tgaatatcaa gataaattaa aaatacaatt attgaaaatc
    39421 gaaaatgaaa tgatgactgt gaacagatca ttaaatgaaa atccaaattc taaaaagaat
    39481 aaatcaaaat taaatcagtt aaatatgcaa ttatctagta ttaataatag aattagtaaa
    39541 accgaagaac taatattaga agatggacct gttttggatt tagctgctgc tttatttata
    39601 tgtactgatg atgaagttta ttatctatca agtggatcaa atcctaaata taatcagtat
    39661 atgggtgcat atcatctaca atggcatatg ataaaatatg caaaatcaca taatattaat
    39721 aggtataatt tttatggaat aacaggcgtc tttagtaatg aggcggatga ttttggtgta
    39781 caacaattta aaaaaggttt taatgcacat gttgaagaat taattggtga tttcatcaaa
    39841 ccagtaagac cgattctatt taaatttgca aaacttattt ataaggtttg attataaagt
    39901 atgttggaaa ttgaaatttt aaattctttc caacatactt ttcactttta aagtcagtat
    39961 ttttactcct ta
//
LOCUS       DAPSKH010000018        39355 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPSKH010000018 DAPSKH010000000
VERSION     DAPSKH010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 39355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39355
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.018"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(406..1335)
                     /gene="hlgA"
                     /locus_tag="RPH49_001033"
     CDS             complement(406..1335)
                     /gene="hlgA"
                     /locus_tag="RPH49_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgAB subunit A"
                     /protein_id="HDY5124211.1"
                     /translation="MIKNKILTATLAVGLIAPLANPFIEISKAENKIEDIGQGAEIIK
                     RTQDITSKRLAITQNIQFDFVKDKKYNKDALVVKMQGFISSRTTYSDLKKYPYIKRMI
                     WPFQYNISLKTKDSNVDLINYLPKNKIDSADVSQKLGYNIGGNFQSAPSIGGSGSFNY
                     SKTISYNQKNYVTEVESQNSKGVKWGVKANSFVTPNGQVSAYDQYLFAQDPTGPAARD
                     YFVPDNQLPPLIQSGFNPSFITTLSHEKGKGDKSEFEITYGRNMDATYAYVTRHRLAV
                     DRKHDAFKNRNVTVKYEVNWKTHEVKIKSITPK"
     gene            complement(1826..3136)
                     /locus_tag="RPH49_001034"
     CDS             complement(1826..3136)
                     /locus_tag="RPH49_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="B domain-containing protein"
                     /protein_id="HDY5124212.1"
                     /translation="MKNKYISKLLVGAATITLATMISNGEAKASENTQQTSTKHQTTQ
                     NNYVTDQQKAFYQVLHLKGITEEQRNQYIKTLREHPERAQEVFSESLKDSKNPDRRVA
                     QQNAFYNVLKNDNLTEQEKNNYIAQIKENPDRSQQVWVESVQSSKAKERQNIENADKA
                     IKDFQDNKAPHDKSAAYEANSKLPKDLRDKNNRFVEKVSIEKAIVRHDERVKSANDAI
                     TKLQKNDSIENRRLAQREVNKAPMDVQKHLQKQLDALVAQKDAEKKVAPKVEAPQIQS
                     PQIEKPKAESPKVEVPQIQSPKVEVPQSKLLGYYQSLKDSFNYGYKYLTDTYKSYKEK
                     YDTAKYYTDKYFKYKGTIDKTVLSVFGNGYKSYIQPLKVEDQKNYVSKSYAQVRNYVT
                     ETLNTGKVLYAFYQNPKVVKAAITTAETATSIKNIFSSFTSFFK"
     gene            3231..3335
                     /locus_tag="RPH49_001035"
     CDS             3231..3335
                     /locus_tag="RPH49_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124213.1"
                     /translation="MLTNRLTSVNYVKKRLIQNIQRILSKEVLYGEMQ"
     gene            3834..4700
                     /locus_tag="RPH49_001036"
     CDS             3834..4700
                     /locus_tag="RPH49_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDY5124214.1"
                     /translation="MSHNENLKLAQRGAYLSLIVYIILSIVKYVTGFVFNSAAVRADA
                     LNNMTDIIVSLAVIIGLKISIKPADRNHPYGHLKSENISSLLVSFVIMFVGIQVVIQN
                     APRLFKEDDVVPNAITIIVSLISGLVMLIVFAVNQRLAKRTKSSSLNSAAKDNLSDSL
                     VSIGTAIGLIFTQIGFPIVDIILATLLGLLIVYTGFGIFKEAIFMLSDGFNETELEAY
                     RNDILEVDEVQEVKSIKGRYHGSSVFIDVTIVVDANLSLVAAHQICDNVEHHLHKKGI
                     SSVYVHPEPDHL"
     gene            5027..5713
                     /locus_tag="RPH49_001037"
     CDS             5027..5713
                     /locus_tag="RPH49_001037"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDY5124215.1"
                     /translation="MPKLILCRHGQSEWNAKNLFTGWEDVNLSEQGINEATRAGEKVR
                     ENNIAIDVAFTSLLTRALDTTHYILTESKQQWIPVYKSWRLNERHYGGLQGLNKDDAR
                     KEFGEEQVHIWRRSYDVKPPAETEEQREAYLADRRYNHLDKRMMPYSESLKDTLVRVI
                     PFWTDHISQYLLDGQTVLVSAHGNSIRALIKYLEDVSDEDIINYEIKTGAPLVYELTD
                     DLEVIDKYYL"
     gene            complement(5867..5971)
                     /locus_tag="RPH49_001038"
     CDS             complement(5867..5971)
                     /locus_tag="RPH49_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDY5124216.1"
                     /translation="MKLDLQTARRNLNSPNIKTRKRALKIIKQHKRAK"
     gene            6145..7584
                     /gene="mdeA"
                     /locus_tag="RPH49_001039"
     CDS             6145..7584
                     /gene="mdeA"
                     /locus_tag="RPH49_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdeA"
                     /protein_id="HDY5124217.1"
                     /translation="MSKKQKLTMIITMLMGGFFGLLNETLLVTALPSIMKDFEISYTQ
                     VQWLTTAFLLTNGIVIPLSALVIQRYTTRQVFLVGISIFFLGTLLGGLSPHFATLLVA
                     RIIQALGAGIMMPLMMTTILDIFQPHERGKYMGIFGLVIGLAPAIGPTLSGCLVEYFN
                     WRSLFHVVAPIAAVTFLIGFKTIKNVGTTIKVPIDFISVIFSVLGFGGLLYGTSSISE
                     KGFDNPIVLVSMIGGVVLVALFVLRQYRLSTPLLNFAVFKNKQFTVGIIIMGVTMVSM
                     IGSETILPIFVQNLLHRSALDSGLTLLPGAIVMAFMSMTSGALYEKFGPRKLALVGMA
                     IVIITTGYFVVMDEQTSTIMLATVYAIRMVGIALGLIPVMTHTMNQLKPEMNAHGSSM
                     TNTVQQIAGSIGTAALITILSHASKNFSPTMSDYNGMNKIEMMNQIKVDTMLHGYHAG
                     FLFALLITVISFFCSFMLQGKKKEVDSHQ"
     gene            7705..8484
                     /locus_tag="RPH49_001040"
     CDS             7705..8484
                     /locus_tag="RPH49_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDY5124218.1"
                     /translation="MKRLLFVVIAFVFILAACGNNSSKDKEASKDSKTINVGTEGTYA
                     PFSFHDKDGKLTGYDIDVIKAVAKEEGLKLKFNETSWDSMFAGLDAGRFDVIANQVGI
                     NPDREKKYKFSKPYTFSSAVLVIRENEKDIKDFDDVKGKKLAQTFTSNYGKLAKDKGA
                     DITKVDGFNQSMDLLLSKRVDGTFNDSLSYLDYKKQKPNAKIKAIKGNAEQSKSAFAF
                     SKKVDDETVQKFNDGLKKIEENGELAKIGKKWFGQDVSKSK"
     gene            8465..9184
                     /locus_tag="RPH49_001041"
     CDS             8465..9184
                     /locus_tag="RPH49_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDY5124219.1"
                     /translation="MFLNLNSEQLHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLI
                     IALFTALMRISTSKVLRSIARVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQW
                     TLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYRQTIQRIILPQA
                     IRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVV
                     CFIISIIQGIYESYIERGYRS"
     gene            9181..9912
                     /locus_tag="RPH49_001042"
     CDS             9181..9912
                     /locus_tag="RPH49_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDY5124220.1"
                     /translation="MIQLNNIHKSFNDVEVIKGIDLSVDKGEVVTLIGRSGSGKTTLL
                     RMINALEIPTEGTVFVNGKTYTSKDKKSQIEVRKQSGMVFQSYNLFPHKTALENVMEG
                     LITVKKLKKAEAREKSLELLEKVGLTHVKDQRPHALSGGQQQRVAIARALAMNPKVML
                     FDEPTSALDPELVNDVLKVIKDLANEGMTMVIVTHEMRFAREVSNNIVFIHEGVIGEQ
                     GAPEEIFNNPKTEELKRFLNVINEE"
     gene            complement(9997..11247)
                     /gene="fmhA"
                     /locus_tag="RPH49_001043"
     CDS             complement(9997..11247)
                     /gene="fmhA"
                     /locus_tag="RPH49_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FemA/FemB family glycyltransferase FmhA"
                     /protein_id="HDY5124221.1"
                     /translation="MNFVTLTSDEFNAFTTKHFSHYTQSAIHYNHRVDLKGDVHLVGV
                     KDDNGQVIAGCLLTEARTLKFFKYFYTHRGPVMDYTNQSLVAFFFKALTSYLKKQNCL
                     YVLVDPYLIENLRNADGEIVKSYDNRAFVRTMDKLGYKHQGFPVGYDSMSQIRWLSVL
                     DLKDKTEDQLLKEMDYQTRRNIKKTYDIGVKTKTLTIDETQTFFDLFHMAEEKHGFKF
                     RELPYFEEMQKLYGDHAMLKLAYIDLNDYLKTLQLKQQQLAAELSGVEEALEESPNSK
                     KNKTKRTQLEQQLSSNKRKIDNTIEQIEQDGAVLNLASALFIYNEHEVYYLSSGSNPK
                     YNAYMGAYHLQWEMIKFAKAHHIDRYNFYGITGDFSESSEDYGVQQFKKGFNAHVEEY
                     IGDFIKPIKPMLYKLQTYLKHKRR"
     gene            11502..11864
                     /locus_tag="RPH49_001044"
     CDS             11502..11864
                     /locus_tag="RPH49_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4467 domain-containing protein"
                     /protein_id="HDY5124222.1"
                     /translation="MKRFVATVLLLLVFISGCGNDKYVKEIDEAVKIQNQKQEQLAKK
                     GNGDRVDHFERKDANIYVYDKDKIIILAYKPLSNDDEVHYYAYDFSDKRVSYKQDFDS
                     RRYYQQHDADYHEENMTN"
     gene            11883..12482
                     /locus_tag="RPH49_001045"
     CDS             11883..12482
                     /locus_tag="RPH49_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDY5124223.1"
                     /translation="MTKKLLTLFIVSMLILTACGKKESATTSSKNGKPLVVIYGDYKC
                     PYCKELDEKVMPKLRKNYIDNHKVEYQFVNLAFLGKDSIVGSRASHAVLMYAPKSFLD
                     FQKQLFAAQQDENKEWLTKELLDKHIKQLHLDKETENKIIKDYKTKDSKSWKAAEKDK
                     KIAKDNHIKTTPTAFINGEKVEDPYDYESYEKLLKDKIK"
     gene            12489..12590
                     /locus_tag="RPH49_001046"
                     /pseudo
     CDS             12489..12590
                     /locus_tag="RPH49_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501155.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12753..13004
                     /locus_tag="RPH49_001047"
     CDS             12753..13004
                     /locus_tag="RPH49_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDY5124224.1"
                     /translation="MIIKNYSYARQNLKALMTKVNDDSDMVTVTSTDDKNVVIMSESD
                     YNSMMETLYLQQNPNNAEHLAQSIADLERGKTITKDIDV"
     gene            13004..13270
                     /locus_tag="RPH49_001048"
     CDS             13004..13270
                     /locus_tag="RPH49_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDY5124225.1"
                     /translation="MARLNITFSPQAFEDYKYFQQNDKKMVKKINELLKSIDRNGALE
                     GIGKPEKLKSNLTGYYSRRINHEHRLVYTVDDKHIKIASCKYHY"
     gene            13564..15114
                     /gene="adcA"
                     /locus_tag="RPH49_001049"
     CDS             13564..15114
                     /gene="adcA"
                     /locus_tag="RPH49_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HDY5124226.1"
                     /translation="MKKKLGMLLLVPAVTLSLAACGNDDGKDKDGKVTIKTTVYPLQS
                     FAEQIGGKHVKVSSIYPAGTDLHSYEPTQKDILSASKSDLFMYTGDNLDPVAKKVAST
                     IKDKDKKLSLEDKLDKAKLLTDQHEHGEEHEHEGHDHEKEEHHHHHGGYDPHVWLDPK
                     INQTFAKEIKDELVKKDLKHKDDYEKNYKKLNDDLKKIDNDMKQVTKDKQGNAVFISH
                     ESIGYLADRYGFVQKGIQNMNAEDPSQKELTKIVKEIRDSNAKYILYEDNVANKVTET
                     IRKETDAKPLKFYNMESLNKEQQKKDNITYQSLMKSNIENIGKALDSGVKVKDDKAES
                     KHDKAISDGYFKDEQVKDRELSDYAGEWQSVYPYLKDGTLDEVMEHKAENDPKKSAKD
                     LKAYYDKGYKTDITNIDIKGNEITFTKDGKKHTGKYEYNGKKTLKYPKGNRGVRFMFK
                     LVDGNDKDLPKFIQFSDHNIAPKKAEHFHIFMGNDNDALLKEMDNWPTYYPSKLNKDQ
                     IKEEMLAH"
     gene            15300..15767
                     /locus_tag="RPH49_001050"
     CDS             15300..15767
                     /locus_tag="RPH49_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SRPBCC domain-containing protein"
                     /protein_id="HDY5124227.1"
                     /translation="MTIKVEDNKIIFSRTIEAPIEKVFDAYTTKALFEKWFHPKDAST
                     KVFRFNAVSGGDAFYAIKTPTMTSYTLAEYKTVKRPYLIEYIDSFATPQGAKDTKMPS
                     MKITLSFSKSNTTKTTVTSTSVFPTKEAAQQVVNMGVEQGMNQTLDQLDALLK"
     gene            15854..16036
                     /locus_tag="RPH49_001051"
     CDS             15854..16036
                     /locus_tag="RPH49_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124228.1"
                     /translation="MVQRYIKVLILYIFTTLLSSITVTSKCVPNKVVRFILRTVVGYG
                     IFAYGLHYFSNLKKNK"
     gene            16239..17063
                     /locus_tag="RPH49_001052"
     CDS             16239..17063
                     /locus_tag="RPH49_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDY5124229.1"
                     /translation="MIKNNKTVEDTYSTKAIVDSISSSVQMKQVMVQQTPGRYMLKSM
                     MAGFLLSIVTVFMFGIKTQFASTHVDGLINLMGAIAFSLGLVLVVLTNSELLTSNFMY
                     FTVGWYYKVVSLNKMMWILLYCFLGNILGGFVLFFLMKYAHVMTPEMTQALTALVQKK
                     TVDSTWLNIFTKGIFCNFFINIGIFISMQFKGGLTKAFFIACGVIVFVYMGYEHVVFN
                     AGLYAGMVFFNLDAVSWLHVLKNIVFAFLGNFVGGGIFVGLVYAFLNGKRNRLEQQ"
     gene            17297..17833
                     /locus_tag="RPH49_001053"
     CDS             17297..17833
                     /locus_tag="RPH49_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124230.1"
                     /translation="MTKTMIRLASEQDAEKLQQLMHEAFTPLRELGIDWPSVNANLDA
                     VKENIDKNTTFVMTIDDEIISTITVRYPWGSVKSISGYPFVWWFATNPEYEGKGYGSQ
                     LLTYVEETFLRDTLKSAAVTLGTSARLHPWLLKIYEKRGYEIYSEHENDDGDLGVIMR
                     KVLIPERFEETILGQPPF"
     gene            18066..18797
                     /locus_tag="RPH49_001054"
     CDS             18066..18797
                     /locus_tag="RPH49_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sirohydrochlorin chelatase"
                     /protein_id="HDY5124231.1"
                     /translation="MNGNIIVAHGMRHGRQNQALEAFISELVKDDIHHYDIAFLESEH
                     QDLETVMTTLIKSGVKKLKIVPLLLFSAMHYLKDIPNIVHEMTQRYPDITVEVSEPLG
                     THPLMRRLIEQRICDALAGDEQQVGVMVVAHGNINGKFTKAHEELQTCVQHLQINKPT
                     YARTLYGEISFIHDLEDIARQYQKLIVVPLFLYDGRLVNKVKQQMNDMVINTDIHITP
                     SINFDPILKQIIKDRLESLMIPMKI"
     gene            18862..21267
                     /locus_tag="RPH49_001055"
     CDS             18862..21267
                     /locus_tag="RPH49_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5124232.1"
                     /translation="MAKQKLVMIGNGMAGIRTIEEILERANDLYDITVIGKEPYPNYN
                     RIMLSNILQNKMTVEETIMNPYEWYEEHGIELITNDPVIEVDRANQNVTTANGIEVAY
                     DKLIFATGSKAFVIPVPGSTLPSVIGWRTIDDTEKMMDIAKTKKKAIVIGGGLLGLEC
                     ARGLLDQGMEVTVLHLAEWLMEMQLDRKAGNMLKADLEKQGMKFEMQANTTEILGEDD
                     VEGVKLADGREIPADLVVMAVGIRPYTEVAKESGLDVNRGIVVNDVMQTSDSNVYAVG
                     ECAEHNGKVYGLVAPLYEQGKVLADHLTNKETDGYKGSTTFTSLKVSGCELYSAGQIV
                     ENAEIKGIEIFNSVDNNYKKVFLKDGNVVGAVLYGDIDDGSRFYNMMKKGESTEDYTL
                     VSLLTKGGEEASLSIADMADDETICGCNGVDKGTIVNAITENGFTTVEEVTAKTKAGN
                     SCGKCKPQIAQILQHTLGDDFVAAKPAGICGCTDLTRDQIVTQIRAKGLKTSKEVRHV
                     LNFKNKGGCPKCRPAINYYLNMVYPHDHEDERESRFANERYHANIQNDGTFSVIPQMR
                     GGVTDADQLIRLGEVAKKYHVPLVKVTGSQRVGLYGVKKEELPNIWEDLGMRSASAYG
                     KKTRSVKSCVGKEFCRFGTQYTTRLGIRLEKTFEYIDTPHKFKMGVSGCPRSCVESGV
                     KDFGIISVENGFQIYIGGNGGTEVEKAEFLTTVETEDEVIKLCGALMQYYRETGIYAE
                     RTAPWLRRLGFENVKEVLLDPERQNELFERIMDAKKAVEAEPWEAITSNAQARKIFEV
                     EKV"
     gene            21271..21585
                     /gene="nirD"
                     /locus_tag="RPH49_001056"
     CDS             21271..21585
                     /gene="nirD"
                     /locus_tag="RPH49_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDY5124233.1"
                     /translation="METKEKIKVTTLDELTPLIGKKVIVKGKEIGLFLTESGTIHAIH
                     NICPHKQGPLSEGTVSGEYVFCPLHDQKIDLNTGIVQEPDEGCVDVYEVEVTDGNVYI
                     CL"
     gene            21576..22553
                     /gene="cobA"
                     /locus_tag="RPH49_001057"
     CDS             21576..22553
                     /gene="cobA"
                     /locus_tag="RPH49_001057"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDY5124234.1"
                     /translation="MSVDEYGKVYLIGAGPGNPNYLTKKAERLIREAEVILYDRLVNP
                     LILQYANLTTEIIDVGKKPYAKHIQQEKINDCIVEAARRYNKVVRLKGGDPAIFGRVQ
                     EEVDTLNNFNIAFEIVPGVTSASAAVATLQTGLTMRTVAKSVTFSTGHFKDSEENEVD
                     VNSLVNGGTLAIYMGVKRLGKIITQIQQYTDIDYPIAIVFQASCFNEFVVKGHLSNII
                     SKLQHYSIEAKPGICIIGEVVGYTENTPKSYDPTKQFYVVSGAKHDALILCEHLYDEG
                     YGCLLNPNDSSNGTYHSSQYDYYDAFIKQQENVTYISTDRADAKTVLCH"
     gene            22857..26546
                     /locus_tag="RPH49_001058"
     CDS             22857..26546
                     /locus_tag="RPH49_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDY5124235.1"
                     /translation="MGKFGLNFFKPTEKFNGNWSILESKSREWEKMYRERWSHDKEVR
                     TTHGVNCTGSCSWKVFVKNGVITWENQQTDYPSCGPDMPEYEPRGCPRGASFSWYEYS
                     PLRIKYPYIRGKLWDLWTEALEENNGNRVAAWASIVENEDKAKQYKQARGMGGHVRSN
                     WKDVTDIIAAQLLYTIKKYGPDRIAGFTPIPAMSMISYAAGARFINLLGGEMLSFYDW
                     YADLPPASPQIWGEQTDVPESSDWYNASYIIMWGSNVPLTRTPDAHFMTEVRYKGTKV
                     ISVAPDYAENVKFADNWLAPNPGSDAAIAQAMTHVILQEHYVNQPNERFINYAKQYTD
                     MPFIIMLDEDENGYKAGRFLRASDLGQTTEQSEWKPVIHDTISDSLVVPNGTMGQRWE
                     EGKKWNLKLETEDGSKINPTLSMTEGGYELETIQFPYFDSDGDGIFNRPIPTRQVTLA
                     NGDKVRIATIFDLMASQYGVRRFDHKLESKGYDDAESKYTPAWQEGISGVKQSVVIQV
                     AKEFAQNAIDTEGRSMIIMGAGINHWFNSDTIYRSILNLVMLCGCQGVNGGGWAHYVG
                     QEKCRPIEGWSTVAFAKDWQGPPRLQNGTSWFYFATDQWKYEESNVDRLKSPLAKTEE
                     LKHQHPADYNVLAARLGWLPSYPQFNKNSLLFAEEAKDEGIDSNEAILQRAIDEMKSK
                     QTQFAIEDPDLKKNHPKSLFIWRSNLISSSAKGQEYFMKHLLGTKSGLLATPNEDEKP
                     EEITWREETTGKLDLVVSLDFRMTATPLYSDIVLPAATWYEKHDLSSTDMHPYVHPFN
                     PAIDPLWESRSDWDIYKTLAKAFSEMAKDYLPGTFKDVVTTPLSHDTKQEISTPYGVV
                     KDWSKGEIEAVPGRTMPNFAIVERDYTKIYDKYVTLGPVLEKGKVGAHGVSFGVSEQY
                     EELKSMLGTWSDTNEDSVRTNRPRIDTARNVADAILNISSATNGKLSQKSYEDLEQQT
                     GMPLKDISSERAAEKISFLNITSQPREVIPTAVFPGSNKQGRRYSPFTTNVERLVPFR
                     TLTGRQSYYVDHEVFQQFGESLPVYKPTLPPMVFGDRDKKIKGGTDALVLRYLTPHGK
                     WNIHSMYQDNKHMLTLFRGGPTVWISNEDAEKHDIQDNDWLEVYNRNGVVTARAVISH
                     RMPKGTMFMYHAQDKHIQTPGSEITDTRGGSHNAPTRIHLKPTQLVGGYAQISYHFNY
                     YGPIGNQRDLYVAVRKMKEVNWLED"
     gene            26536..28095
                     /gene="narH"
                     /locus_tag="RPH49_001059"
     CDS             26536..28095
                     /gene="narH"
                     /locus_tag="RPH49_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDY5124236.1"
                     /translation="MKIKAQVAMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNV
                     ETKPGVGYPKRWEDQEHYKGGWVLNRKGKLELKSGSRISKIALGKIFYNPDMPLIKDY
                     YEPWNYNYEHLTTAKSGNHSPVARAYSEITGDNIEIEWGPNWEDDLAGGHVTGPKDPN
                     IQKIEEDIKFQFDETFMMYLPRLCEHCLNPSCVASCPSGAMYKRDEDGIVLVDQDACR
                     GWRYCMTGCPYKKVYFNWKTNKAEKCTFCFPRIEAGMPTVCSETCTGRMRYLGVLLYD
                     ADRVHEAASAVDEKDLYEKQLDIFLNPFDEEVIAQAEKDGISYDWIEAAQNSPIYKLA
                     IEYKLAFPLHPEFRTMPMVWYCPPLSPIMSYFEGKNTNQNPDAIFPAIEEMRLPIEYL
                     ANIFTAGDTKPVKEALQRMAMMRSYMRSQVTQQPFDTSRLERLGLTERQTKDMYRLLG
                     LAKYEDRFVIPTSHKETYLDTYHAQGSTGYNYGGEHFGDNCEGCGVAVGSGKTGQEIY
                     NENFYGGIFRD"
     gene            28088..28663
                     /gene="narJ"
                     /locus_tag="RPH49_001060"
     CDS             28088..28663
                     /gene="narJ"
                     /locus_tag="RPH49_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000606770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDY5124237.1"
                     /translation="MINFDNFKKYQESFGYIAQQLCFPEKLTFHPKTFEETISKDHPG
                     YDDLIAFRNVMMTFSLSEIKAIYTDTFDFTKKAPLYMTYNKFDTQKERGQMLAKLKVL
                     YEMFGLEMVDNELSDYLPLMLQFLQVAEWRNDPRAEENIQLIIMIIEDGTYVMANALG
                     EDNNPYAYVIQALRKTLKLCLTSPKGVKHHA"
     gene            28656..29333
                     /gene="narI"
                     /locus_tag="RPH49_001061"
     CDS             28656..29333
                     /gene="narI"
                     /locus_tag="RPH49_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDY5124238.1"
                     /translation="MLNQFLWVIFPYLCLVVFVAGHIARYRYDKFSWTAKSSELIERK
                     RLMWGSLLFHLGIIPVFFGHVVGLLIPKSWMDAAGVSEHLYHIGAVYIGSIFGIITLV
                     GMFLLTARRVTTKSIRRLSSASDIFVNFLLLLIVFMGCYATLVTNIQHPDFNYRTSLS
                     IWFRQLFMLKPDASLMSGVPIAFKIHILLGFTIMACWPFTRLVHVWSVPLTYINRRYI
                     IYRKNKV"
     gene            29353..29805
                     /gene="nreA"
                     /locus_tag="RPH49_001062"
     CDS             29353..29805
                     /gene="nreA"
                     /locus_tag="RPH49_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation accessory nitrate
                     sensor NreA"
                     /protein_id="HDY5124239.1"
                     /translation="MTPEAIIEDRRFQETLDKIRKEEGYDFAAIAFYESNKPSSPIKW
                     HYVSGNKNNRFKLIILRKGRGLAGTVMKTGKRMIIANVGLALGPEEKIDYPILLSESL
                     TAVLAVPLWYKNQVYGVLLFGQRDGRPLPKIFDNDDIQRKFGIFNDDK"
     gene            29829..30863
                     /gene="nreB"
                     /locus_tag="RPH49_001063"
     CDS             29829..30863
                     /gene="nreB"
                     /locus_tag="RPH49_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501138.1"
                     /note="Involved in the regulation of the the nitrate
                     reductase operon narGHJI; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation sensor histidine
                     kinase NreB"
                     /protein_id="HDY5124240.1"
                     /translation="MINEDSIQLEALLKKYYEHSIEKIVFADDSGKIIAMNDAAKDIL
                     SEEDNYSAVANAICHRCEGYTNAYDVQSCKDCFLESMQVQATNFQVFMKTKDQKVMPF
                     TATYQLIDQDRGIHAFTLQNVSSQIEQQEKLHQQRMMRKTISAQENERKRISRELHDS
                     VIQEMLNVDVQLRLLKYQEDTAKLLEDAENIEYIVAKLIDDIRNMSVELRPASLDDLG
                     LEAAFKSYFKQFEENYGIKIIYTSNIKNTRFDSDIETVVYRVVQEAILNALKYADVNE
                     INVGIRQTGRHLVAEVIDAGNGFDPSSKPKGSGLGLYGMNERAELVSGSVNIETKIGE
                     GTNVTLNIPI"
     gene            30886..31539
                     /gene="nreC"
                     /locus_tag="RPH49_001064"
     CDS             30886..31539
                     /gene="nreC"
                     /locus_tag="RPH49_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002464689.1"
                     /note="Involved in the regulation of the the nitrate
                     reductase operon narGHJI; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate respiration regulation response
                     regulator NreC"
                     /protein_id="HDY5124241.1"
                     /translation="MKIVIADDHAVVRTGFSMILNYQNDMEVVATAADGVEAYQKVME
                     YKPDVLLMDLSMPPGESGLIATSKIADSFPETKILILTMFDDEEYLFHVLRNGAKGYI
                     LKNAPDEQLLLAIRTVYKGETYVDMKLTTSLVNEFVSNSNQDTANTSDPFKILSKREL
                     EILPLIAKGYGNKEIAEKLFVSVKTVEAHKTHIMTKLGLKSKPELVEYALKKKLLEF"
     gene            complement(31793..32533)
                     /locus_tag="RPH49_001065"
     CDS             complement(31793..32533)
                     /locus_tag="RPH49_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDY5124242.1"
                     /translation="MAYTYTLKDIIEITGVTKRTLHYYDEIGLLVPDKNDKNYRVYKQ
                     QDLEKLQKILILKSFDFDIAKIKQYISYDNEQLRKLLSEQISKLDKKISDLQLIRRSV
                     CEFIKGHSLIDTSILNKTLQSQYDKEASIKYGHTKAYQSFIRRKDNLQSQDIRQKLST
                     IFNKFNHMSLSHYPIQDCNDIVTEWKSFMNTIADFDDETLCCIAKTYEDDTRFKDYFN
                     SYDNQNLASYISEAVNYFLSNVNKSDNF"
     gene            complement(32512..33426)
                     /locus_tag="RPH49_001066"
     CDS             complement(32512..33426)
                     /locus_tag="RPH49_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000276756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2268 domain-containing protein"
                     /protein_id="HDY5124243.1"
                     /translation="MYKINIIRSDSVYKKILKAPLNERDSIFTKEILVPFKKKFEVQQ
                     IPIHNDDKQTMSAIQLLDVFHKSPEELVETDQMSIQYLNNDFWINCEKYLKVAIDQFA
                     NYSISSQVSNYHFTVLLGDSQKPLMYLNKNRGGDGGIPGYIMIYLVPSTSTINSMKSL
                     IAHEVNHNMRYQYIDWDGGSLIELIIAEGLAENYVESLYGKAHIGPWVTNTNWSRDNV
                     KIKNTIYNHLHLKHIFESMPYLYGDDINKLQGRPIVGLSHAAGYACGYHLVKYFLQKS
                     NIPIEVATTLPAQKIINEVTEFWHTHTL"
     gene            33796..34965
                     /locus_tag="RPH49_001067"
     CDS             33796..34965
                     /locus_tag="RPH49_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NarK/NasA family nitrate transporter"
                     /protein_id="HDY5124244.1"
                     /translation="MYKTKGGFQLTLQTLSLVVGFMAWSIIAPLMPFIKQDVNVTEGQ
                     ISIILAIPVILGSVLRVPFGYLTNIVGAKWVFFTSFIVLLFPIFFLSQAQTPGMLMAS
                     GFFLGVGGAIFSVGVTSVPKYFPKEKVGLANGIYGMGNIGTAVSSFLAPPIAGIIGWQ
                     TTVRSYLIIIALFALIMFIFGDTQERKIKVPLMAQMKTLSKNYKLYYLSYWYFITFGA
                     FVAFGIFLPNYLVNHFGIDKVDAGIRSGVFIALATFLRPIGGILGDKFNAVKVLMIDF
                     VIMIIGAVILGISDHIALFTVGCLTISICAGIGNGLIFKLVPSYFSNEAGSANGIVSM
                     MGGLGGFFPPLVITYVANLTGSSHLAFIFLAVFGCIALFTMRHLYQKEYGSLKHS"
     gene            complement(35073..35501)
                     /locus_tag="RPH49_001068"
     CDS             complement(35073..35501)
                     /locus_tag="RPH49_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDY5124245.1"
                     /translation="MILNFNQFENQNFFNGNPSDTFKDLGKQVFNYFSTPSFVTNIYE
                     TDELYYLEAELAGVNKEDISIDFNNNTLTIQATRNAKHKSEQLILDERNFESLMRQFD
                     FEAVDKQHITASFENGLLTITLPKIKPSNDTTSSTSIPIS"
     gene            complement(35716..36162)
                     /locus_tag="RPH49_001069"
     CDS             complement(35716..36162)
                     /locus_tag="RPH49_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5124246.1"
                     /translation="MYVENSYLSKQLCFLFYVSSKEIIKKYTNYLKDYDLTYTGYIVL
                     MAIENDEKLNIKKLGERVFLDSGTLTPLLKKLEKKDYVVRTREEKDERNLQISLTEQG
                     KAIKSPLAEISVKVFNEFNISEREASDIVNNLRNFVSKNFDNSDKK"
     gene            36559..36924
                     /locus_tag="RPH49_001070"
     CDS             36559..36924
                     /locus_tag="RPH49_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3139 domain-containing protein"
                     /protein_id="HDY5124247.1"
                     /translation="MKKKKNVIKVIIILFISLIVAVAFFFGLKTYQGHKNIQLIDSYL
                     EEKSLKDKIKSEKTEYSAKKGLFYKEVTFKDEPGVTYVVQPISTNKGLFVEGFDTETK
                     KSLKTAKHKYFNQNYKPSK"
     gene            37106..38383
                     /locus_tag="RPH49_001071"
     CDS             37106..38383
                     /locus_tag="RPH49_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:dicarboxylase symporter family
                     transporter"
                     /protein_id="HDY5124248.1"
                     /translation="MALFKRKISLPMQVVIALVLGVVVGLLLYGQENVANYIKPFGDV
                     FLNLIKMIVIPVVFCSLALSISNVGESKTVGRYGWKTILYFEIITTIAIGLGIIFGNL
                     FKPGAGLDPTKLPKGDISKYQSTAHAAEQSTYGNHFIDTIVHIIPTNFFEALNKGELL
                     PIIFFAVFFGLGLAAVGKKAEPVKEFLSGSLEAVFWMINKILKLAPLGVFAFICTTII
                     TFGASALLPLLKLVLVVVFAMVFFVFAILGLVAWMCGINIMNIIRILKSELLLAFSTS
                     SSEAVLPVMMKKMENFGSPKEITSFVIPIGYTFNLDGSALYQSIAALFVAQMYGMHLT
                     LSEQIVLMLTLMITSKGMAAVPGTSIVVLLTTLGAMGLPAQGLALIIGVDRILDMVRT
                     CVNVIGNALSTIVIAKWENVYDKAKGQEYLKSI"
     gene            complement(38882..39238)
                     /locus_tag="RPH49_001072"
     CDS             complement(38882..39238)
                     /locus_tag="RPH49_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4889 domain-containing protein"
                     /protein_id="HDY5124249.1"
                     /translation="MKNKKGFGLGISLIAIMLIVCIVLVIMMMTGGKKDTYYGIMKDN
                     ATIEKMISEKDESIEKNVKLPSDADVSVKKGDFVIVYKLADSDKIVKVKKVDHDDVPH
                     GLMMKIHDMGKMHMKH"
BASE COUNT        13404 a         5576 c         7428 g        12947 t
ORIGIN      
        1 gaatgctaaa agctaatttt gtgagaaata tagttaataa aaccttggta ttgttgacag
       61 ttgtaaacaa tttaaggtaa ccgattgcac gaatgttttg ctttcatttt taattaatgt
      121 ttgtaaaata caaattgtgc ttttttacga tttttgatga atccatctaa aagttaattg
      181 tttattaact tgagaatatt aatttaagct ttcaacttaa attgcttcat ttgtattatt
      241 tgtgtatcta ctatggtgcg atactttgtt cttataaaaa tcagttgtta ttattaaatt
      301 taatgtacga taaaataatt taatgttatg aggctgattc aatatgttaa aaaatcctga
      361 gacaagtatg aagtgtccca ggatttttta aaatgattga actgtttact taggtgtgat
      421 gcttttaatt tttacttcat gtgttttcca gttcacttca tatttaactg taacgtttcg
      481 gtttttaaaa gcatcatgtt ttctatcaac ggctaaacga tgtcttgtca cgtaagcata
      541 tgtagcatcc atgtttctgc cgtaagtgat ttcaaactcg cttttatcac ctttaccttt
      601 ttcgtgtgac aatgttgtaa taaatgatgg attaaagcca ctttgaatta aaggaggtag
      661 ttgattatct gggacgaaat agtctcttgc tgctggacca gttgggtctt gggcaaataa
      721 gtattgatca tatgcagata cttgaccatt cggtgtaacg aatgaatttg ctttcactcc
      781 ccatttaaca cctttagagt tctgactttc tacttcagta acatagtttt tttgattata
      841 actaattgtt ttagagtagt tgaatgagcc actgcctccg attgatggcg ctgattggaa
      901 gtttccgccg atattatagc ctaatttttg actaacatct gctgaatcaa ttttattttt
      961 aggaagataa ttgattaaat caacattaga gtctttcgtt ttcaaactga tattatattg
     1021 aaatggccat atcattcttt taatatatgg atattttttt aagtctgaat atgttgttct
     1081 agagctgatg aagccttgca tcttaacaac tagggcatct ttgttatatt ttttatcttt
     1141 tacaaaatca aattgaatgt tttgagttat agctaatcgt ttgctagtaa tgtcttgtgt
     1201 tcttttgatg atttctgcac cttgcccgat atcttctatc ttattttctg ctttagaaat
     1261 ttctataaat ggattagcta aaggggcgat taaaccaact gctaaagttg ctgttaatat
     1321 tttattttta atcatagaaa tcactttctt tctatttaat tttaagttca tatatataat
     1381 aatctatttg taagcgtttt cgaattaact gttcgttaaa agttaattac tatcaacatg
     1441 tattgaagag acatttttag cattgttaaa tgatgttttt gcattatgtt atgtttagaa
     1501 gatttattgg tcgcaggcgt ttatatagcg acataactat gttttgcaag tcttattcta
     1561 ttgaattaat gtttaattaa ggtgcttgaa gtggaagggg aatgaattgc gcaatagttt
     1621 gtgaaaattt gaagttaata aagttgagct gattcaacta aatgatgaac tattcgttaa
     1681 cgatgtaagg attatttaac aagttgcagg taaaaaagtg ggctgacaag tagcgaagaa
     1741 acatttaatt gatggaaaat gaaaaaagaa ccgtagattc gattgagaat caacggttct
     1801 ttttaatcac ggtttattac gaaaattatt taaaaaatga tgtaaaacta gagaagatat
     1861 ttttgattga tgttgctgtt tcagctgtag ttatagcagc tttaactact tttggatttt
     1921 gataaaatgc atataatact ttacctgtgt ttaaagtttc agttacatag tttcttactt
     1981 gtgcatatga tttagataca taattttttt gatcttcaac ttttaatggt tggatgtatg
     2041 atttgtatcc attaccaaaa actgatagta cagttttatc tattgtacct ttatatttaa
     2101 aatatttatc agtgtagtac tttgctgtat catatttttc tttatagctt ttataagtat
     2161 ctgttaaata cttgtaacca tagttaaatg aatcttttaa tgattggtag taacctaata
     2221 atttagattg aggaacctca acttttggcg attgaatttg agggacttca acttttggtg
     2281 attctgcttt aggtttttca atttgtggtg attgaatttg aggagcctca acttttggcg
     2341 ccactttctt ttcagcatct ttttgagcta ctaatgcgtc taattgtttc tgtaagtgct
     2401 tttgtacatc cataggtgct ttattaactt cacgttgtgc taaacgtctg ttttcaattg
     2461 aatcattttt ttgtaattta gtaatggcat cgtttgctga tttcacacgc tcatcatgac
     2521 gaacgatcgc tttttcaatt gaaacttttt ctacaaagcg gttattttta tcacgtaaat
     2581 ctttaggtaa ttttgagtta gcttcatatg ctgctgattt atcgtgtggt gctttgttat
     2641 cttggaaatc tttaattgct ttatccgcat tttcaatatt ttgacgttct ttagctttag
     2701 aagattgtac tgattctacc caaacttgtt ggcttctatc agggttttct ttaatttgtg
     2761 caatgtaatt atttttttct tgttcagtta agttatcatt tttaagaaca ttgtaaaaag
     2821 cgttttgttg tgcaacacgt cggtctgggt tcttgctgtc tttaagtgat tcagagaata
     2881 cttcttgtgc acgttctggg tgttcgcgta atgttttgat gtattggtta cgttgttctt
     2941 ctgtgatacc ttttagatgt aatacttgat aaaaagcttt ttgttgatct gttacgtagt
     3001 tgttttgagt tgtttggtgc ttagttgaag tttgttgcgt gttttcactc gcttttgctt
     3061 ccccatttga aatcattgta gctaaagtaa ttgttgctgc cccaactagc aacttcgaga
     3121 tatatttatt tttcatgtgt attccctttc tttttacata ttaaatttat tgtatgcttt
     3181 tagaatttat cacatgagaa tacaaatgga aattaactaa ttattaacta atgttaacta
     3241 atagattaac tagtgttaac tatgtaaaaa aacgtttaat tcagaacatt cagcgtattt
     3301 taagtaagga agtactatat ggagaaatgc aatagtttgc taataaatag aggagaaaat
     3361 tgtgtttcga agagagtttg gtagagtaga aatctcattt gatttgtcac tgatgcactt
     3421 tttcttctat ataattaggt cacgacatta gatagcttcg caactaatgc atagggtccc
     3481 aacatagcaa ctttcgaggc gaaagttcac aaacagggag agttgggcgc ctttctaaca
     3541 aataaatttg aagaagacga aggaacgcag ttggacgtaa aacgtcaact gcataagcct
     3601 ttctagctca taaaattcgc agaaaataaa ggaacgcatt agatagcttc gctactaatg
     3661 cataagcctt tctagctcat aaaattcgca gaaaggctaa aaaatatttt taggggttgc
     3721 gaatgaataa attagtttta ttttataaaa atttataaaa attaaaaacg ttgtaaaatt
     3781 aaaataaatc attcataata ttgttactat actaattcaa ggtggttcaa cgcatgtctc
     3841 ataatgaaaa tcttaaattg gcgcaacgcg gtgcttattt gagtttgatt gtatatataa
     3901 tcttatctat tgttaagtat gtcacaggtt ttgtctttaa ctctgcagct gtaagagccg
     3961 acgcattaaa caatatgaca gatattatcg tttctttagc tgttattatt ggattgaaaa
     4021 tttcaattaa acctgccgat cgaaatcatc cttatggcca tttgaagtct gaaaatattt
     4081 cttcattatt ggtgtcattt gtcattatgt ttgtaggtat ccaagtagtt attcaaaatg
     4141 cacctcgttt gttcaaagaa gatgacgttg tacctaacgc aataacaatt atcgtcagct
     4201 taatcagtgg tcttgtaatg ttgattgtat ttgcagtcaa tcaaagacta gcgaaaagaa
     4261 cgaaaagtag ttctttaaat tctgccgcca aagataattt atcagatagt ttagtcagca
     4321 ttggaacggc gataggatta atttttacgc aaatcggttt cccaattgtc gatattattt
     4381 tagcaacatt gctaggctta ctaatcgttt atactggttt tggtattttt aaagaagcaa
     4441 tttttatgtt gagtgatggt ttcaatgaaa ctgaattaga agcgtatcgc aatgatattt
     4501 tagaagttga tgaagtacaa gaagttaaaa gtattaaagg gcgttaccat ggaagtagtg
     4561 tgtttattga tgtcacaatt gttgtagatg ctaacctttc cttagtagca gcgcatcaaa
     4621 tttgtgacaa tgtcgaacat catttgcaca aaaaaggtat ttcctcagta tacgttcacc
     4681 cagaaccaga ccatctataa tgtatttaaa cgtcttcata gatatataaa tatctgagga
     4741 ggcgttttta ttacatttat ttttaggtgc acctaaaaat attttttaaa ccttagaaaa
     4801 atggcgaaca aaggtgtata atatgatttg ttattaggtg gttattgatt catttatgaa
     4861 ttaaaaaatg aaaatgggga ataggattta tgtatttaat gtttagtgat aattgattta
     4921 atcattgaat tttaaaacat attgaaaaga aaattgctaa gattaaatca tcttaaaata
     4981 tccctgaaat aacgtcctaa agattaaagg aaagaggtta taagttatgc caaaattaat
     5041 tttatgtcgt catggacaaa gcgagtggaa tgctaaaaac ttatttactg gatgggaaga
     5101 tgttaattta tctgaacaag gtattaatga agcgactaga gcaggtgaaa aagtaagaga
     5161 aaataacatt gccatcgatg tagcttttac atcgttatta acacgtgctt tagatacaac
     5221 gcattatatt ttaactgaat ctaaacaaca atggattcct gtatataaaa gctggcgttt
     5281 aaatgaacgc cactatggtg gattgcaagg cttaaataaa gatgatgcta gaaaagaatt
     5341 tggagaagaa caagtacata tttggcgtcg ttcttatgat gtgaaaccgc ctgctgaaac
     5401 cgaagaacaa cgtgaagctt acttagctga tcgtcgatat aatcatttag ataaacgtat
     5461 gatgccttat tctgaaagtc tgaaagatac tttagttcga gtgataccat tttggacaga
     5521 tcatatttca caatatttgc tagatggtca aacggtatta gtttctgcac acggaaattc
     5581 aattcgagca ttgattaaat atcttgaaga tgtgtcagat gaagatatca ttaattatga
     5641 aattaaaaca ggtgcaccgc ttgtttatga attaaccgat gatttagaag ttatagataa
     5701 atactactta taaaaaaaga gctgcatgta cacaaggagt gagtgtatat gcagctctta
     5761 aatatgtgaa gtaatgtaag gaaatagtta agtatagagt ttatattaac gagctaggga
     5821 tactcgaaaa tatagttaga catacaatat agtcaaatta aaacaattat ttcgctcttt
     5881 tgtgttgctt aataatcttt aaagcacgct ttcttgtttt aatgttaggg ctatttaaat
     5941 tacgacgagc agtctgtaaa tctaatttca tctctatccc tccttgtaaa tatattatga
     6001 ccgataacta ctcatatgta aatagtaatg attacgtttt aaagaaattg taataaagtc
     6061 gtgctaattt ttttgaaaat gggtataatt accggatatc taaaaatgtg tgtcgttttt
     6121 tagatggtga gggggaagct ttaaatgtcg aagaaacaaa aattaacgat gattattact
     6181 atgctgatgg gtggattttt tggattatta aatgaaacac tattagtgac ggctttacca
     6241 agtattatga aagattttga aatttcatat acacaagttc aatggctgac aacagctttt
     6301 ttattgacta atgggattgt tattcctttg tccgcgcttg ttatacaacg ttatacaaca
     6361 agacaagtgt ttttagtggg tatttctatc tttttcttag gtacattact cggcggtttg
     6421 agtccacact ttgcaacatt attagttgct agaattattc aggcgttagg tgctggaatt
     6481 atgatgcctt taatgatgac aacgatttta gatatttttc aaccgcatga gcgtggtaaa
     6541 tatatgggca tatttggcct cgttattggt ttagcaccag ctattggacc tactctttca
     6601 ggttgccttg ttgaatattt taactggaga tcgcttttcc atgttgtcgc tccaattgca
     6661 gctgtgacat ttttaattgg atttaaaacg ataaaaaatg ttggaactac aattaaagta
     6721 cctattgatt ttatttctgt cattttttct gtactaggtt tcggcgggtt attgtatgga
     6781 acgagttcaa tttcggaaaa aggttttgat aatcctatcg tattagtttc gatgattgga
     6841 ggcgttgttt tagtcgcatt atttgtatta cgtcaatatc ggctatcaac accattatta
     6901 aattttgcag tatttaaaaa taaacaattt acagttggta tcattattat gggtgtcaca
     6961 atggtatcaa tgattggttc ggaaacgatt ttaccaattt ttgtgcaaaa tttattgcat
     7021 cgttcagctt tagattctgg gttaacttta ttaccaggag caattgttat ggcatttatg
     7081 tcgatgactt caggtgcctt atatgaaaag ttcggtccaa gaaaattagc tttagtcggt
     7141 atggcaatcg ttattattac cactggttac tttgttgtaa tggatgaaca gacatcgaca
     7201 attatgttgg caacggttta tgcgattcga atggttggta tcgccttagg tttaattcct
     7261 gttatgacgc atacaatgaa tcaattaaaa cctgaaatga acgcacacgg ttcatctatg
     7321 acaaacacag tacaacaaat tgctggttct atcggaacag ctgcattaat tactatttta
     7381 tctcatgcaa gcaaaaactt ttctccaact atgtcagact ataatggcat gaacaaaatt
     7441 gagatgatga atcaaattaa agttgatacg atgttacatg gttatcacgc tggattttta
     7501 tttgcactat tgattacagt gattagtttc ttttgttcat ttatgttaca aggaaagaaa
     7561 aaagaagttg attcacatca ataaatataa gttgctagct atataaagct ttttagcaaa
     7621 agttcaacat attgacttat ccggcatttc agattaaaat atttttattc cgattagaat
     7681 aataagaata aggagatata ttctatgaaa agacttttat ttgtggtgat agctttcgtt
     7741 ttcatattag ctgcatgtgg gaacaattcg tctaaagaca aggaagctag taaagatagc
     7801 aagacaatta atgttggtac tgaggggact tatgcaccat ttagtttcca tgataaagat
     7861 ggtaaattaa ctggttacga tattgatgtt attaaagcag tagctaaaga agaaggttta
     7921 aaacttaaat ttaatgaaac ttcttgggat tctatgtttg caggtttaga cgcagggcgt
     7981 tttgatgtaa tcgcgaacca agtgggtatt aatcctgata gagaaaagaa atataaattt
     8041 tctaaacctt acacattctc aagtgctgtt ttagttattc gtgaaaatga aaaagatatt
     8101 aaagattttg atgatgttaa aggtaagaag ttagcacaaa cattcacatc taattatggt
     8161 aaattagcta aggataaagg tgctgatatt acaaaagttg atggttttaa ccaatcaatg
     8221 gatttattat tgtctaagcg tgttgatggt acatttaatg acagtctgtc atacttagat
     8281 tataaaaaac aaaaacctaa tgctaagatc aaggcaatca aaggtaacgc tgaacaaagt
     8341 aaatctgcat ttgcattttc taaaaaagtg gatgacgaaa cagttcaaaa attcaatgat
     8401 ggcttgaaaa aaatcgagga aaacggtgaa ttagctaaaa taggtaagaa atggtttggt
     8461 caagatgttt ctaaatctaa atagtgaaca actacatgca cttgatgccg caaaacaagc
     8521 ttttgggcct atgctcgaag gtctggtgaa atattcaatt ccgattaccc tcgtaacatt
     8581 tgtattaggg ttaatcattg cattatttac agcattgatg cgcatttcaa cgagtaaagt
     8641 tttaagaagt attgcacgtg tctatgtatc tattattcgt gggacaccta tgatagtaca
     8701 attatttatc atcttttatg gtattccaga attaggtaga ttattaacta atgatgcaga
     8761 taatcaatgg acattggcgc ctgtggtcgc tgccattatt ggtttgtcat taaatgtagg
     8821 tgcatatgct tcagaaatta ttcgtggcgg tattatttct ataccaaaag gacaaacaga
     8881 agctgcatat tctatcggta tgacatatcg tcaaacgata cagcgcatca ttttaccgca
     8941 ggcaattcga gtatctatac ctgcactagg taatacattt ttaagtttaa tcaaagatac
     9001 atcattacta ggatttattt tagtggctga aatgtttaga aaagctcaag aagttgcgtc
     9061 tacaacatat gaatatttaa caatttatgt gttagttgcg ctaatgtact gggtggtatg
     9121 ctttattatt tcaataatcc aaggtatcta cgaatcttat attgaaagag ggtatcgctc
     9181 atgattcaat tgaacaatat ccataaatca tttaatgatg ttgaagtcat caaaggtatt
     9241 gatttatctg ttgacaaagg tgaggttgta accttaattg gccgatctgg gtcaggtaaa
     9301 acaacgttgt tacgaatgat taatgcgtta gaaattccaa ctgaaggtac agtatttgtt
     9361 aacggcaaaa catatacatc taaagataaa aaatcacaaa tagaagttcg taaacaatct
     9421 ggtatggtat ttcaaagcta taatcttttt ccgcataaga cggcattaga aaatgtaatg
     9481 gaaggtctta ttacagttaa aaagttgaaa aaggctgaag ctcgtgagaa atctctagaa
     9541 ttacttgaga aagttggttt gacacatgtc aaagatcaac gaccacatgc attatcaggt
     9601 ggtcaacagc aacgtgttgc cattgcgaga gcattagcta tgaatcctaa agtgatgttg
     9661 tttgatgaac caacatctgc acttgatcct gaacttgtga atgatgtgtt aaaggtgatt
     9721 aaagatttag cgaatgaggg catgacaatg gtcattgtga cacatgaaat gcgttttgct
     9781 agagaagtat ctaataacat tgtattcatt catgaaggtg taattggaga acaaggggca
     9841 cctgaagaga tttttaacaa tccaaaaact gaagaactaa aacgtttttt aaatgttatt
     9901 aatgaagaat aaacaaatag aaccacgaat cttgtttgat tacggcgaag atgccactag
     9961 caagattcgt ggtttttgat gttacagcat aaactgttaa cggcgtttat gttttaagta
    10021 tgtttgtaat ttgtaaagca taggtttgat tggtttaata aaatcaccaa tatattcttc
    10081 gacgtgtgcg ttaaatcctt ttttgaattg ttgtacgcca taatcttctg atgactctga
    10141 aaagtcaccg gtaataccat agaaattata gcgatcaata tgatgcgctt tagcaaactt
    10201 aatcatttcc cactgcaaat ggtaggcacc catataagca ttatatttag ggtttgaacc
    10261 actagataag taataaactt catgctcatt gtagataaac aaagcagaag ctaagttcaa
    10321 cactgcacca tcttgttcaa tttgttctat tgtattatca atttttcgct tattactgct
    10381 taactgttgt tctaactgtg ttcgtttcgt tttatttttc tttgaattcg gactttcttc
    10441 caatgcctct tcaacacctg agagctcagc agctaattgc tgttgtttca attgtaatgt
    10501 tttcaaataa tcatttaaat cgatataagc taactttaac atggcgtgat caccatatag
    10561 tttttgcatt tcttcaaagt atggtaactc acggaatttg aaaccgtgct tttcctcagc
    10621 catatggaat aagtcgaaaa aggtttgcgt ttcatcaatc gttaacgttt tagttttgac
    10681 accaatatca tatgtttttt taatattacg tctcgtttga taatccattt cttttaaaag
    10741 ttggtcttca gtcttatctt ttaaatctaa cactgacagc caacggattt ggctcattga
    10801 atcataacct acagggaaac cttggtgttt ataacctaat ttatccattg ttctaacaaa
    10861 tgctcggtta tcataagact taacaatttc accgtctgca ttgcgtaaat tttcaattaa
    10921 atatggatct acaaggacat ataaacaatt ttgtttcttt aaatatgacg ttaatgcttt
    10981 aaagaaaaat gctactaatg attgatttgt ataatccatc actggcccgc gatgtgtata
    11041 aaaatatttg aaaaatttaa gtgtgcgtgc ttctgtcaat aagcatcctg caatcacttg
    11101 accattgtca tctttaaccc ctacaagatg cacatcgcct tttaaatcaa ctctatgatt
    11161 gtaatgaata gctgattgtg tgtaatgtga aaaatgcttt gttgtaaacg cattgaactc
    11221 atccgaagtc aacgttacaa agttcatttt atcccatccc tctctgaatt gaactgtaat
    11281 ttttgaattt atttataatg ctattttttt attttatcaa aaactgattg taaatacaca
    11341 tagaaaatga aatatatttt tctttgacta tacataactg ttatttcttt ggatatttat
    11401 attaaatgca ttggtagtag ttgtagcgca ttgatgtttg acggtgtata gtattaatta
    11461 tattgaaagt tagttggaag ttgatagtag gagtgggagc attgaagcga tttgtggcga
    11521 cggtattatt attactagtc tttatatcag gatgtggtaa tgataaatat gtgaaagaaa
    11581 tagatgaagc agttaaaatt caaaatcaaa aacaagaaca acttgccaaa aaaggcaacg
    11641 gtgatcgtgt tgatcatttt gaacgcaaag atgctaatat ttatgtctat gataaggata
    11701 aaattatcat tttagcttat aaacctttga gtaatgatga tgaagtgcat tattatgcat
    11761 atgattttag tgataaacgt gtatcatata agcaagattt tgattcgaga cgatattatc
    11821 aacaacatga tgcggattat catgaagaaa atatgacgaa ctagatatga acaggagtta
    11881 ttatgactaa aaaattacta acattattta tagtgagcat gttaatttta acagcttgcg
    11941 gtaaaaaaga atcagcaacg acatcttcga aaaacggcaa accattagtt gtcatatatg
    12001 gcgactataa atgtccttat tgtaaagaat tagatgaaaa agtcatgcca aagttgcgta
    12061 aaaattatat agataatcac aaagtggaat accaatttgt caatttagct ttcttaggta
    12121 aagactcaat tgttggttcg cgtgcgagtc atgcagtatt gatgtatgca cctaaatcat
    12181 ttttagattt tcaaaagcaa ttatttgctg cccagcaaga tgaaaataaa gaatggttaa
    12241 caaaagaact attagataaa catattaaac aactgcattt agataaagag acggaaaata
    12301 aaattataaa agattacaag acaaaagata gcaagtcttg gaaagctgca gagaaagata
    12361 aaaaaatagc taaagataat catataaaaa cgacaccaac tgcatttatt aatggcgaga
    12421 aagttgaaga tccatatgat tatgaaagtt atgagaagtt attaaaagat aaaatcaaat
    12481 agtcttaatt gttgagataa gtaagtgata ccaatttttt aggacaatat gaaaaggcaa
    12541 tttctattag caatatgata gagattgtct ttttaatgta tgaagtctaa atgggtggaa
    12601 attatcatgt aaacattttt tagtagggaa tcagtacagg ataggtattg attcttcccc
    12661 gtgcaaaatc ttgattagta atttttttgt gtcgcttgtt ttattgtaca gatatttgta
    12721 caattgaggt gtgttaaaag gaggcgataa atatgattat taaaaattat tcatacgctc
    12781 gacagaattt aaaggcactt atgacaaaag taaatgatga tagtgatatg gtaactgtaa
    12841 catctactga tgataaaaac gtagtaatca tgtcagaatc agattataac tccatgatgg
    12901 aaacacttta cctccaacag aacccaaata atgctgagca cttagctcaa tcaattgcag
    12961 atctagaacg tgggaaaact ataacgaaag atatagatgt ataatggcta ggttaaatat
    13021 tacgttttcg cctcaagcct ttgaagatta taagtatttt cagcagaacg ataaaaaaat
    13081 ggtgaagaag attaatgagt tacttaaaag tattgacaga aatggtgcat tggaaggtat
    13141 aggtaagcct gaaaagttaa aatcgaatct gactgggtat tatagtagac gtatcaatca
    13201 cgaacataga ttggtttata cagtagatga caagcatata aaaatagcat catgtaaata
    13261 ccattattaa atctaaaagt cacactataa aaatagggta agttatttta ggacaatatg
    13321 aaaaggcaat ttctattagc aatatgatag agattgtctt ttttcttata ttatgacgtt
    13381 cgtaaatact ataaagtttt ctgtatcata tttgtacaat agtcatgtat tagataaaac
    13441 gaaaagtggt aaatacctaa agtatgattc gactttatat tatttataaa aacagtgctt
    13501 gtattttaag tagcatgagt atataatttt aaaacgtaaa gattactatt taggagggtg
    13561 actatgaaaa agaaattagg tatgttactt cttgtaccag ccgtaacttt atcattagcc
    13621 gcatgtggga atgatgatgg aaaagataaa gatggcaagg taacaattaa aacgacagtt
    13681 tatccattgc aatcatttgc agagcaaatt ggtggaaaac acgtgaaggt atcatcaatc
    13741 tatccagcag ggacagattt acatagctat gaaccaacac aaaaagatat attaagtgca
    13801 agcaagtcag acttgtttat gtatacaggg gataatttag atccggttgc taagaaagtt
    13861 gcatctacta tcaaagataa agataaaaaa ctgtctttag aggataaatt agataaagca
    13921 aagcttttaa ctgatcaaca cgagcatggt gaagagcatg aacatgaggg acatgatcat
    13981 gagaaagaag aacatcatca tcatcatggt ggatatgatc cacacgtatg gttagatcct
    14041 aaaattaacc aaactttcgc taaagaaatt aaagatgaat tagtgaaaaa agatctaaaa
    14101 cataaagatg actatgagaa aaactacaaa aaattaaacg acgatcttaa gaaaattgat
    14161 aacgatatga agcaagttac aaaagataag caaggtaatg cagtattcat ttcacatgaa
    14221 tcaattggat acttagctga tcgttatggt tttgttcaaa aaggtattca aaacatgaat
    14281 gctgaagatc catcacaaaa agaattaact aaaattgtta aagaaattag agatagcaat
    14341 gctaaatata ttctttacga agataatgtt gcgaataaag tgactgaaac aattcgtaaa
    14401 gaaacagatg cgaagccttt aaaattctac aacatggagt ctttaaataa agaacaacag
    14461 aaaaaagata atattacgta tcaatcatta atgaaatcga atattgaaaa tatcggtaaa
    14521 gctttagaca gtggtgttaa agtgaaagac gacaaagctg aaagtaaaca cgataaagca
    14581 atttctgatg ggtattttaa agatgagcaa gttaaagacc gtgaattaag cgattatgct
    14641 ggtgaatggc aatctgttta cccttactta aaagacggta cgcttgatga agtgatggaa
    14701 cataaagctg aaaatgatcc gaagaaatct gctaaagatt taaaagctta ctatgacaaa
    14761 ggatataaaa ctgatattac taacattgat ataaaaggaa atgaaattac atttactaaa
    14821 gatggtaaga aacacactgg taaatatgaa tacaatggta agaaaacatt gaaatatcct
    14881 aaaggtaacc gtggcgtgag atttatgttt aaattggtcg atggtaatga taaagactta
    14941 ccgaaattca tccaatttag cgatcacaac attgcaccta aaaaggcaga acacttccat
    15001 atctttatgg gtaatgataa tgacgcgtta ttaaaagaaa tggataactg gccaacatat
    15061 tatccttcaa aattaaataa agaccaaatc aaagaagaaa tgttagcgca ttaattcaac
    15121 aggtttgcac actctactca actgttaata gctgaataga gtgtgttttt tatttcgtag
    15181 ttatcaattt caacagaggg aatgattaat attactatag tttataacaa atgatttggt
    15241 aacatatgtt actcaatgca tgttaagatg agtaaatata aaagataggg agtgggaaga
    15301 tgacgattaa agttgaagat aataaaatta ttttttcaag aacgatagaa gcaccgattg
    15361 aaaaggtgtt tgatgcctat acgacaaaag cattatttga aaaatggttt catccaaaag
    15421 acgctagtac caaagtgttt cgctttaatg ctgtttcagg cggtgatgca ttttatgcga
    15481 ttaaaacacc tacaatgacc agctatacat tagcagaata taaaacggtt aagcgtccat
    15541 atttaattga atatattgac tcatttgcga cacctcaagg tgcaaaagat acgaaaatgc
    15601 caagcatgaa aattactttg tcattttcca agagcaatac aacgaaaacg acagttacat
    15661 caacatcggt atttccaaca aaagaagccg ctcaacaagt cgtaaacatg ggtgttgagc
    15721 aagggatgaa tcaaacatta gatcaacttg atgctttatt gaaataaagt tgttgaaaat
    15781 atgtaaaaat ttttatatgc cattcagttt ataataataa cgtaatatta ttaattgaat
    15841 gaaggatgat tcgatggtac aacgttacat taaagtatta atattatata tttttactac
    15901 acttttatct tcaattactg ttacttcgaa atgtgtacca aataaagttg ttagatttat
    15961 tttgcgtaca gtcgtaggct acggtatatt tgcatatggt ttacattact tttcaaattt
    16021 aaaaaagaat aagtaatact tacataaagc gagatgagcg caattaaaat gataccaatt
    16081 gttttatgtc gcgatatcta tctcgctatt tttatgagta aatattagtt ttgaattggt
    16141 aaaaagaatt ttctgaattt taatctatga attacatcta aatactaata taattaatag
    16201 gtaaaattta tttgataata gtaaatgggg gaagtgctgt gataaaaaat aataaaacag
    16261 ttgaagatac gtattcaact aaagcaatcg tagactcaat atcatcatct gttcaaatga
    16321 aacaagtgat ggtacagcaa acaccaggac gatacatgct aaaatctatg atggcaggtt
    16381 tcttattgtc cattgttact gtttttatgt ttggtattaa aacacaattc gcaagtacac
    16441 atgttgatgg tctcattaat ttaatgggag caattgcttt cagcttagga ttggtcttag
    16501 ttgtactaac gaattctgaa ttattaacaa gtaattttat gtattttaca gttggctggt
    16561 attataaagt tgtttctctt aataagatga tgtggatttt attatattgt ttccttggaa
    16621 atattttagg tggttttgta ttattcttct taatgaaata tgcacatgtt atgacaccag
    16681 aaatgacaca agctttaact gccttagttc agaaaaaaac agtcgattcg acttggttga
    16741 atatttttac aaaaggtatt ttctgtaact tctttattaa tatcggtatt tttatttcta
    16801 tgcaattcaa aggcggattg acaaaagcat tcttcattgc ttgtggcgtt atagtctttg
    16861 tatacatggg atatgagcac gttgtattca atgctggttt atatgcaggt atggtgttct
    16921 tcaaccttga tgcagtttca tggttacacg ttttaaaaaa tatcgttttt gctttcttag
    16981 gtaactttgt cggtggcggt atttttgtag gtctcgttta tgctttctta aatggtaagc
    17041 gtaatcgttt agagcaacaa taattaagat gtagtgatta aatagcgtaa caatgaatca
    17101 ttcttccaaa ccattcatga atttgaatgg tttttttacg ttgagagagt aatttttaat
    17161 aagtttcatg agagtattgg tgtattcaga tgaagcatac tttctgacat gtgataaatt
    17221 tattgataca ctttgatgga tatttatttt aaaaataaaa tatggttaaa tcatttaaaa
    17281 aagagtgggg attaatatga caaaaacgat gattcgactc gcaagtgaac aagatgcaga
    17341 aaaattgcaa caactcatgc atgaagcatt tacgcctcta agagaacttg gcatagactg
    17401 gccttcagta aatgcaaatt tagatgctgt gaaagaaaat atagataaaa atactacatt
    17461 tgtcatgaca attgatgatg aaattatatc tacgattacg gtcagatatc cttggggaag
    17521 tgtgaaaagc atttcgggct atccttttgt ctggtggttt gcgacaaatc ctgagtatga
    17581 agggaaaggc tatggtagcc aattacttac ttatgttgaa gaaacatttt tgcgagatac
    17641 gttaaagtca gcggcagtta ctttaggtac atctgcaaga ttgcatccgt ggttacttaa
    17701 aatttatgaa aaaagaggtt atgaaatata cagcgaacat gaaaatgatg atggcgattt
    17761 aggtgtaatc atgcgtaaag tattaatacc tgaacgtttt gaagaaacga ttctaggcca
    17821 accaccattt taagataata atatacacta caagcgaccg atatattgat gcttgctcaa
    17881 atgaatgaat gttgagtagg gattaacata ttggtcgctt ttttgattta acaaaaaggg
    17941 aaaatttata aggaatatgc atgactacag gcatcaggga attccctgat tttacattat
    18001 aatgtgattc ttttcacaaa aacgaaatga tttggtatac aatacgtgtg aaagggttgg
    18061 taaatgtgaa tgggaatatc attgttgcac atggcatgag gcacggacga cagaatcaag
    18121 cgttagaagc atttatttct gaattagtaa aagatgatat acatcactat gatattgcat
    18181 ttttagaaag tgagcatcag gatttagaaa cagtaatgac gacgttgatt aaaagtggcg
    18241 ttaaaaagct taagattgta cctttgcttc tctttagtgc catgcactat ctcaaggata
    18301 taccgaatat cgttcatgaa atgacacagc gttatccaga cataacggta gaagtaagcg
    18361 agccacttgg tacacatcct ttaatgagac gattaattga acaacgtatt tgtgacgcat
    18421 tagcaggtga cgaacaacaa gttggagtta tggttgttgc acatggcaat attaatggca
    18481 agtttacaaa agcacatgaa gagttacaga catgcgttca acatttgcag attaataaac
    18541 ctacttatgc gagaacgcta tatggtgaaa tcagttttat acatgattta gaagatattg
    18601 cgagacagta tcaaaaattg attgtcgtac ctttattttt atatgacgga agacttgtta
    18661 acaaagtgaa gcagcaaatg aatgacatgg ttattaatac agatatacac atcacacctt
    18721 caattaactt cgacccaatt ttaaagcaaa tcattaaaga tagattagaa agcttaatga
    18781 ttccaatgaa aatataaaag cactaacgaa aaattaaacc tttttttgaa ataaatatta
    18841 tgtagtaaag gggcatattt tatggcaaag caaaaactag taatgattgg taacggtatg
    18901 gcgggcattc gaacaatcga agaaatatta gagcgtgcca atgatttata tgatattaca
    18961 gtaattggta aagaacctta tcctaattat aatcgcatca tgctttcaaa tattttacaa
    19021 aataaaatga cagttgaaga aacaattatg aatccatatg agtggtatga ggaacatggt
    19081 atcgagttaa ttacaaatga tcctgtaatt gaagtagata gagcaaatca aaatgtaacg
    19141 actgcaaatg gtattgaagt agcatacgat aaattaatat ttgcgacagg atctaaagca
    19201 tttgtcattc cagtgccagg ttcgacctta ccaagtgtta ttggctggag aacaattgat
    19261 gacactgaaa aaatgatgga cattgctaag actaaaaaga aagcgattgt tatcggtggg
    19321 ggcttattag gtttagaatg tgcacgtggt ttattagatc aaggtatgga agtaacagtg
    19381 ttgcatttgg ctgagtggtt gatggaaatg cagttagacc gtaaagctgg aaatatgctt
    19441 aaagcagatc tagaaaagca aggtatgaag tttgaaatgc aagccaacac aactgaaatc
    19501 ttaggagaag atgatgttga aggtgttaaa ttggctgatg gacgcgagat tccggcagac
    19561 ttagttgtta tggcagtagg tattcgacca tacacagaag tagccaaaga atcaggtcta
    19621 gatgttaatc gtggtattgt tgtcaatgat gtgatgcaaa caagtgatag caatgtatat
    19681 gcagtcggtg aatgtgcaga acataacggt aaagtttatg gtttagttgc acctttatat
    19741 gaacaaggta aagtattggc agatcattta acgaataaag aaacagatgg atacaaaggt
    19801 tccactacat ttacatcatt aaaagtttct ggttgtgagc tatatagtgc tggtcaaatt
    19861 gttgaaaatg ctgaaatcaa aggtattgaa atatttaata gtgttgataa taactataaa
    19921 aaagtatttt taaaagatgg aaatgtggtc ggtgcagtct tatatggtga tatcgatgat
    19981 ggttcacgct tttataacat gatgaaaaaa ggtgaatcta ctgaagatta cacactggta
    20041 tcattgctta ctaaaggtgg agaagaggca tcgctatcaa ttgctgatat ggctgatgat
    20101 gaaacaattt gtggttgtaa tggtgttgat aaaggtacta tagtaaatgc tattacggaa
    20161 aatggcttta caacagttga agaagtaacg gctaaaacaa aagcggggaa ttcatgtggt
    20221 aaatgtaaac cgcaaattgc tcaaatattg cagcacacct taggagatga ctttgttgcc
    20281 gcaaaacctg ctggtatatg tggttgtact gatttgacac gcgatcaaat tgtaacgcaa
    20341 ataagagcaa aaggtttaaa aacatctaaa gaagttcgac atgttttaaa ctttaaaaat
    20401 aaaggtggat gtccaaaatg tcgaccagca atcaactatt atttaaacat ggtttatcca
    20461 catgatcatg aagatgaaag agaatcaaga tttgctaacg aacgttacca tgcgaatatt
    20521 caaaatgatg gtacattttc tgttatacct caaatgcgtg gaggtgttac agatgcagac
    20581 caactgattc gtctaggaga agtggctaag aaatatcatg tgccactagt taaagtgaca
    20641 ggttcgcaac gtgttggttt gtatggagtt aaaaaagaag aattaccaaa tatatgggaa
    20701 gacttaggta tgcgttcagc atcagcttat ggtaagaaaa cacgctcagt taaaagctgt
    20761 gtcggcaaag agttttgtcg atttggtacg caatacacga cacgacttgg cattcgttta
    20821 gaaaaaacat ttgaatacat cgatacacct cataaattca aaatgggtgt atcaggctgc
    20881 ccaagaagtt gtgttgaatc aggtgttaaa gattttggta ttatctcagt tgaaaatgga
    20941 ttccaaatct atatcggtgg taatggtggt acagaagttg aaaaagctga atttttaaca
    21001 actgtagaaa cagaagatga agtaatcaaa ttatgtggtg ctttgatgca atattatcgc
    21061 gagacaggta tttatgctga aagaacagca ccgtggttaa gaagactagg gtttgaaaat
    21121 gttaaagaag tgttgcttga tccagaaaga cagaatgaat tatttgaacg tattatggat
    21181 gctaaaaaag cagtcgaagc tgaaccttgg gaagcaatca ctagtaatgc gcaagctcga
    21241 aaaatctttg aagtggagaa ggtgtaatac atggaaacga aagagaaaat caaagtgaca
    21301 actttagatg aattgacacc cttaattggt aaaaaggtta ttgtcaaagg caaagaaata
    21361 ggattgtttt taactgaaag tggtacaatt cacgcgattc acaatatttg tccgcataaa
    21421 caagggccat tgtcagaggg aacagtgagt ggtgaatatg tattctgtcc actccatgat
    21481 caaaagattg atttaaatac tgggattgta caagaacctg atgaaggttg tgtagatgtt
    21541 tatgaggtag aagttacaga cgggaacgta tatatatgtc tgtagatgaa tatggcaagg
    21601 tttacttgat aggtgcggga ccaggtaatc cgaattattt gactaaaaag gctgagcgtt
    21661 taatacgtga agcggaagtt atactatatg atcgattagt gaatccgttg attttacaat
    21721 atgcgaattt gactactgaa attatcgatg ttggtaaaaa gccgtatgca aaacacattc
    21781 agcaagaaaa aataaatgac tgtatcgtgg aagcagcacg tcgatataac aaggttgtga
    21841 ggcttaaagg tggcgaccca gcaatatttg gacgagttca agaagaagtt gacacactaa
    21901 acaactttaa tattgcgttt gaaattgtac ctggtgtgac atctgcgagt gctgcagttg
    21961 ctactttgca gacaggtttg acaatgcgta cagttgctaa aagtgtgaca ttttctacag
    22021 gtcactttaa agattcagaa gaaaatgaag tggatgtcaa ttccttagtg aatggtggta
    22081 cgttagcgat ttatatgggg gtaaaacgtt tagggaaaat tatcacacag atacaacagt
    22141 acacagatat tgattatccg atagcgattg tctttcaagc atcgtgtttt aacgagtttg
    22201 ttgttaaggg gcatttaagt aatattattt caaaattgca acactattca attgaggcga
    22261 aaccaggtat atgtattatt ggggaagttg ttggttatac tgaaaacact cctaaatcat
    22321 atgatcctac gaagcaattt tatgtagtaa gtggtgctaa acatgacgcc cttatcctct
    22381 gtgaacattt atatgacgaa ggttatggct gtttgctaaa cccaaatgat tcatcgaatg
    22441 gcacatatca ttcgtcgcaa tatgattact atgatgcgtt tattaagcag caagaaaatg
    22501 taacatatat ttcaaccgat cgtgcagatg ctaaaacagt gttatgtcac taatttataa
    22561 aaaatgaata agtaaggttt caaccgagag aatatattcg tgttgaagcc ttatttgtcg
    22621 ttgtgccaaa tttgaacgat ttagattggc aataaacatg gtcatatgtg attgtgtaaa
    22681 atttcaataa aatccaatta ttgataggga aaatccttaa gtaattaggt aattccctaa
    22741 tattttatat ttgtgaaaaa atgtacaatc taattaaagc aatagtcttg ggcattttta
    22801 gtatttaaaa acacgacatc tacacatcgt atttttatac gtaggaggat ataaatatgg
    22861 gaaaatttgg attgaatttc tttaagccaa cagaaaaatt taatgggaat tggtcgatcc
    22921 tagaaagtaa aagtagagaa tgggaaaaaa tgtacagaga acgttggagc catgataaag
    22981 aagtaagaac aacgcatggt gttaactgta ctggatcatg ttcatggaaa gtctttgtga
    23041 aaaatggtgt gattacctgg gaaaatcaac aaactgacta tcctagttgt ggtccggata
    23101 tgcctgaata tgaaccgaga ggctgtcctc gtggtgcatc attctcttgg tatgaataca
    23161 gcccacttcg aattaaatat ccatatattc gtgggaagct ttgggattta tggactgaag
    23221 cattagaaga aaacaatggc aatcgtgtgg ctgcatgggc ttctattgtt gaaaatgaag
    23281 acaaagccaa acagtataag caagcccgtg gtatgggtgg acatgtgcgt tcaaattgga
    23341 aagatgttac ggatattatc gcagcacaat tactatatac aattaaaaaa tatggtccag
    23401 atcgaatcgc aggatttaca cctattccag cgatgtcgat gattagttat gcagcaggtg
    23461 ctcgattcat caatttgctt ggtggtgaaa tgcttagttt ttatgactgg tatgcagatt
    23521 taccacctgc ctctccacaa atttggggag agcaaacaga tgtgcctgaa tcaagtgact
    23581 ggtataacgc atcatacatt attatgtggg gctctaatgt accactaacg cgtacgccag
    23641 acgcacattt tatgacagaa gttcgctata aaggaacaaa agttatttca gtagcacctg
    23701 attatgcaga aaatgtgaag tttgctgata actggttagc cccgaatcct ggttcagatg
    23761 ctgcaattgc tcaagcgatg acacatgtta ttttacaaga gcattatgtt aatcaaccga
    23821 atgaacgctt tattaattat gcgaaacaat atacagacat gccatttatc atcatgttag
    23881 atgaagatga aaatggatat aaagcgggta gatttttaag agcaagtgac ttaggacaaa
    23941 cgacagagca aagtgaatgg aaaccggtaa tccacgacac aatcagtgac agtttagtgg
    24001 tacctaatgg cacaatgggg caacgttggg aagaaggtaa gaagtggaac ttaaaactag
    24061 aaacagaaga tggttctaaa attaacccta cattatcaat gacagaaggt ggatatgaat
    24121 tagaaacaat tcaattccca tactttgata gtgatggaga tgggatattc aatcgtccaa
    24181 ttccaactcg acaagtcact ttagcaaatg gtgacaaagt ccgtattgct acaatttttg
    24241 acttaatggc aagtcaatat ggcgtgcgtc gttttgatca taaattagaa tcaaaaggat
    24301 acgacgatgc agaatcaaaa tatacacctg cttggcaaga aggcatttca ggcgtaaaac
    24361 aaagtgttgt cattcaagta gcgaaagaat ttgcgcaaaa cgctatcgat actgaagggc
    24421 gttcaatgat tatcatgggt gcgggtatta accattggtt taactcagat acgatttatc
    24481 gttcaatctt aaacttagtt atgttatgtg gctgtcaagg tgtgaatggt ggcggttggg
    24541 ctcactatgt gggacaagaa aaatgtcgcc caattgaagg atggagtact gtcgcatttg
    24601 cgaaagactg gcaaggacca ccacgtttgc aaaacggaac aagttggttt tattttgcta
    24661 cagaccaatg gaaatatgaa gagtcaaatg tagatcgttt aaaatctcca ttagctaaaa
    24721 cagaggagtt aaaacatcaa catccagctg attataatgt gttagcagct agacttggtt
    24781 ggttaccatc atatccacaa tttaataaaa atagcttgtt gtttgcagaa gaagctaaag
    24841 atgaaggtat agattcaaat gaagcgattt tgcaacgtgc aattgatgaa atgaaatcaa
    24901 aacaaacaca atttgcaata gaagatcctg atttgaaaaa gaatcatcca aaatcattat
    24961 ttatatggcg ttcaaactta atttcaagtt ctgcaaaagg tcaagaatac tttatgaagc
    25021 atttacttgg cacaaaatca gggttattag ctacaccaaa tgaagatgaa aagccagaag
    25081 aaattacgtg gcgtgaagaa acaacaggta agttagattt agtggtctct ttagacttca
    25141 gaatgacggc aacaccgtta tattctgaca ttgttttacc ggcagcaact tggtatgaaa
    25201 aacatgattt atcatcaacg gatatgcatc catatgtaca tcctttcaat cctgccattg
    25261 atccattatg ggaatcacgt tcagactggg atatttataa aacattggca aaagcatttt
    25321 cagaaatggc aaaagactat ttacctggaa cgtttaaaga tgttgtgaca actccactta
    25381 gtcatgatac aaagcaagaa atttcaacac catacggcgt agtgaaagat tggtcgaagg
    25441 gtgaaattga agcggtacct ggacgtacaa tgcctaactt tgcaattgta gaacgcgact
    25501 acactaaaat ttacgacaaa tatgtcacgc ttggtcctgt acttgaaaaa gggaaagttg
    25561 gagcacatgg tgtaagtttc ggtgtcagtg agcagtacga agaactaaaa agtatgttag
    25621 gcacgtggag tgacacaaat gaagattctg tcagaacgaa tcgtccacgt attgatacag
    25681 cacgtaatgt cgctgatgcc atacttaata tttcatcagc tacgaatgga aagttatcac
    25741 agaaatcata tgaggatctt gaacaacaaa ctggtatgcc attgaaagat atttctagtg
    25801 agcgtgctgc tgaaaaaatt tcgtttttaa atataacatc acaaccacgt gaagttatac
    25861 caacagcagt attcccggga tctaataagc aaggccgacg ttactcacca tttacaacga
    25921 atgtagaacg tttagtgcct tttagaacat taacaggacg tcaaagttat tatgtggatc
    25981 acgaagtttt ccaacagttt ggtgaaagct taccagtata taaaccaacg ttaccaccaa
    26041 tggtatttgg tgatagagat aagaaaatta aaggtggtac agatgctttg gtactgcgtt
    26101 atttaacgcc tcatggaaaa tggaatatac actcaatgta tcaagataat aagcatatgt
    26161 tgacactatt tagaggtggt ccaacggttt ggatatcaaa tgaagatgct gaaaaacacg
    26221 atatccaaga taatgattgg ctagaagtgt ataaccgtaa tggtgttgta acggcaagag
    26281 cagttatttc gcatcgtatg cctaaaggta caatgtttat gtatcatgca caagataaac
    26341 atattcaaac gcctgggtca gaaattacag atacacgtgg tggttcacac aacgcgccga
    26401 ctagaatcca tttgaaacca acacaactag tcggaggata tgcacaaatt agttatcact
    26461 ttaattatta tggaccaatt gggaaccaaa gggatttata tgtagcagtt agaaagatga
    26521 aggaggttaa ttggcttgaa gattaaagcg caagttgcga tggtattaaa tttagataaa
    26581 tgcataggat gccatacgtg tagtgtgaca tgtaaaaaca cttggacaaa tcgtccaggt
    26641 gctgagtaca tgtggttcaa caacgtagag actaagccag gtgtagggta tccgaaacgt
    26701 tgggaagacc aagaacacta caaaggtggt tgggtactaa atcgtaaagg gaaacttgaa
    26761 ttaaaatctg gaagtagaat ttcaaaaatt gcattaggga aaatattcta taatccagat
    26821 atgccactaa ttaaagatta ttacgagcca tggaactata attatgaaca tttaacaact
    26881 gcgaaatcag gtaatcattc tccagttgct agagcgtatt cagaaattac gggggataac
    26941 attgaaattg aatggggacc taactgggaa gatgacttag caggtggtca tgttacaggt
    27001 ccaaaagatc ctaacatcca aaaaatagaa gaagatatta aattccaatt tgacgaaaca
    27061 tttatgatgt acttaccacg tttgtgtgaa cattgcttga atccaagttg cgttgcatcg
    27121 tgtccttcag gtgctatgta taaacgtgat gaagatggca tcgtgctagt tgaccaagat
    27181 gcttgtcgtg gttggcgtta ctgtatgaca ggttgtccat ataaaaaagt atacttcaac
    27241 tggaaaacga acaaagcaga aaaatgtact ttctgtttcc cgagaattga agcggggatg
    27301 cctacagtgt gttctgaaac ttgtacagga cgtatgcgtt atttaggtgt tttattatat
    27361 gatgcagatc gagttcatga agcagcttca gcagtagacg agaaagattt atacgaaaaa
    27421 caattagata tattcttaaa tccatttgac gaagaagtca ttgcacaagc tgaaaaagat
    27481 ggcattagtt atgattggat tgaagctgca caaaactcac caatttataa gttagcgatt
    27541 gaatataaac tagcatttcc attacatcct gaatttagaa cgatgccgat ggtttggtat
    27601 tgcccaccac ttagcccaat tatgagctat ttcgaaggta aaaatacaaa tcaaaatccg
    27661 gatgcgattt tcccagccat tgaagaaatg cgcttgccga ttgaatattt agcgaatatt
    27721 ttcacggcag gagatacaaa accagtaaaa gaagcattgc agcgtatggc aatgatgaga
    27781 agttacatgc gttcccaagt tacacaacaa ccatttgata catcacgttt agagcgatta
    27841 ggtttaactg aacgacaaac taaagatatg tatcgcttat taggactagc taaatatgaa
    27901 gatcgattcg ttattccaac gtcacataag gaaacatatt tagatacgta tcatgctcaa
    27961 ggtagtacgg gatataacta tggtggcgaa cactttggtg ataactgtga aggttgtggt
    28021 gttgcagtag gttcaggaaa aactggtcaa gaaatttata atgagaattt ctatggaggg
    28081 attttccgtg attaatttcg ataattttaa aaagtatcaa gaaagttttg gatatatagc
    28141 gcaacagcta tgctttccgg aaaaattaac atttcatcca aagacttttg aagaaacaat
    28201 ttcgaaagat catccaggct atgacgattt aatagcattt agaaatgtaa tgatgacatt
    28261 ttctttatca gaaatcaaag cgatttatac agatacattt gattttacga aaaaagcacc
    28321 attatatatg acgtataaca agtttgatac acaaaaagaa cgtgggcaaa tgttagcgaa
    28381 actaaaggta ttgtacgaga tgtttggact agaaatggta gacaatgaac tttctgatta
    28441 tctaccgttg atgttgcaat ttttacaagt ggcagaatgg agaaatgatc caagagctga
    28501 agagaatatt caattaatca ttatgattat tgaggatgga acatatgtga tggcgaatgc
    28561 acttggtgaa gataacaatc catatgccta tgtgattcaa gcgcttagaa aaacattgaa
    28621 attatgtttg acatcaccaa aaggagtgaa acatcatgct taatcagttt ttatgggtta
    28681 tatttccgta tttatgttta gttgtctttg tcgcaggtca tattgcacgt tatcgttatg
    28741 ataaattttc gtggacagca aaatctagtg aattaattga aagaaaaaga ttgatgtggg
    28801 gtagtttatt atttcactta ggtattattc cggtattttt tggacatgtt gtaggattat
    28861 taatacctaa gtcgtggatg gatgctgccg gtgtgtctga gcatttatat catattggtg
    28921 ctgtttatat agggagtatc tttggtataa ttacattggt agggatgttt ttattaacag
    28981 cgagacgtgt tactacgaaa agtattcgca gattaagttc agcgtccgat atctttgtta
    29041 acttcttatt attacttatt gtatttatgg gatgttatgc aacattagta acaaatatac
    29101 agcatccaga ttttaactat agaacttcat tatcaatttg gtttagacaa ttatttatgt
    29161 tgaaaccaga tgcatcatta atgagtggtg taccaattgc atttaaaatt catatattat
    29221 taggtttcac tattatggct tgttggccat tcacacgttt agtacatgtt tggagtgtac
    29281 ctttgacata tataaatcgc agatatatta tttaccgtaa gaataaagtg taagtataag
    29341 aggtgaaagg atttgacacc agaagcaatt attgaagatc gtagatttca agagacatta
    29401 gataaaatac gcaaagaaga aggttatgat tttgcggcaa tcgctttcta tgaatctaac
    29461 aaaccatcat ctccaataaa atggcactat gtttcaggta ataaaaataa tcggtttaaa
    29521 ttaattattt taagaaaagg ccgtggatta gctggaactg ttatgaaaac agggaagcgt
    29581 atgattatag ctaatgtcgg tttagcattg ggaccagaag aaaagattga ctatccaatt
    29641 ttattaagcg aatcattaac agcagtttta gcagtgccgc tttggtataa gaatcaagtg
    29701 tatggcgtac tattatttgg tcaaagagat ggacgtcctt taccaaaaat atttgataac
    29761 gatgatattc aacgtaagtt tggtattttc aatgatgata aataatgaga tgaattaggg
    29821 tgtaggtcat gattaatgag gacagtatac aattagaagc tttattaaaa aaatactatg
    29881 aacattcaat cgaaaaaata gtatttgccg acgatagtgg taaaattatt gcaatgaatg
    29941 atgctgctaa agatatatta tctgaagaag ataattacag tgctgtggcg aatgcgattt
    30001 gtcacagatg tgaagggtat acaaatgcct atgatgtaca atcatgtaaa gattgtttct
    30061 tagagtccat gcaagtacaa gctacgaatt ttcaagtgtt tatgaagacg aaagatcaaa
    30121 aagtgatgcc gtttactgca acttatcagc ttattgatca ggatagaggg attcatgcat
    30181 ttacgcttca aaatgtctca tcacagattg aacaacaaga aaaattgcat caacaacgta
    30241 tgatgcgtaa aacgatttcc gcacaagaaa atgagcgaaa acgaatttct agggaattac
    30301 atgatagtgt gattcaagaa atgttaaatg tagatgttca attgcgattg ttgaaatatc
    30361 aagaagatac agcaaagctt ttggaagacg cagaaaatat tgaatatatt gtcgctaaat
    30421 taattgatga tatacgtaat atgtcggttg aattaagacc cgcttctttg gatgatctag
    30481 gccttgaggc agcttttaaa tcatatttta aacagtttga agaaaattat ggaataaaaa
    30541 tcatatatac atcaaatatt aaaaataccc gctttgatag tgatattgaa acggttgttt
    30601 atcgagtagt gcaagaagct attctaaatg cgttgaaata cgctgatgta aatgaaataa
    30661 atgtaggtat ccgtcaaact gggcgacatt tggttgctga agtgatagat gcgggaaatg
    30721 gttttgatcc aagttctaag cctaaaggtt ctggactcgg tttatatgga atgaatgagc
    30781 gagctgaatt agtcagtggt agcgtcaaca tcgaaacgaa aattggtgag ggtaccaatg
    30841 ttacattgaa cattccaatt tgaaacatac attgggggaa taaaattgaa aatagtcatt
    30901 gccgatgatc acgctgttgt ccgtacgggg ttctctatga ttttaaatta tcaaaatgat
    30961 atggaagttg ttgcaacggc tgcagatggc gtcgaagctt accaaaaagt aatggaatat
    31021 aaacctgatg tgttactaat ggatttaagt atgccaccag gtgagtcagg tcttatcgct
    31081 acgagtaaaa ttgctgacag ttttcctgaa actaaaatac taatattaac aatgtttgat
    31141 gatgaggagt atttgttcca tgtgttgcgt aatggtgcga aaggttacat attgaaaaat
    31201 gcacctgatg aacaattatt gttagctatt cgaactgtat ataaaggtga aacatatgta
    31261 gatatgaaac ttacaacatc tttagtgaat gaatttgtat ctaattcaaa tcaggacact
    31321 gcaaacacat cagatccttt taaaatatta tcaaaacgag aactagaaat attaccactt
    31381 attgccaaag gttacgggaa taaagaaatt gcagagaaat tatttgtttc tgtaaagaca
    31441 gtagaggcac ataagacgca tattatgaca aagcttggct tgaaaagtaa accagagctc
    31501 gttgaatatg cattgaaaaa gaaattatta gagttttaat gtttgaaaat aataccatac
    31561 aaagcgccag aggaaacggg gaatcttctg gcgcttttgt atgtttcgaa atatattttt
    31621 tttataaatc gaatggaacc taatcctttc tcctttcgat aacctatact aattcgcttt
    31681 gcaaaggtac aacttttaat atagttattg atttagagaa taaatgatta gttttctact
    31741 ttgaacaatt attttagttg gtgtattcag tgttgtagca tctgtatgag gattaaaaat
    31801 tgtcgctctt attcacattg ctcaaaaaat aattaacagc ttctgaaatg tatgatgcta
    31861 aattttgatt atcatatgaa ttaaagtaat ctttgaaacg cgtatcatct tcatatgttt
    31921 tagcaataca gcataatgtt tcatcatcaa aatcagcgat agtattcata aaagatttcc
    31981 attctgtcac gatatcatta cagtcttgga ttggataatg actcaaagac atatgattaa
    32041 atttattgaa gattgttgac aatttctgtc tgatatcctg tgattgtaag ttatctttac
    32101 gtctaataaa tgattgatat gctttcgtat gaccatattt tatagatgct tctttatcat
    32161 attgtgactg tagtgtcttg tttaaaatgc tggtatctat tagagaatgt cctttaataa
    32221 attcacatac agagcgtcta attaattgta agtcagaaat ctttttatct aacttgctta
    32281 tttgctctga taataacttt cgcaattgtt cattatcata tgaaatgtat tgttttattt
    32341 tagcgatatc aaaatcaaaa gacttgagta ttaaaatctt ttgtaatttt tctaagtctt
    32401 gctgtttata aacgcgataa tttttatcat ttttatctgg aactaataat cctatttcat
    32461 cgtaataatg taaagttctt ttagttacac ctgtaatttc aataatatct tttaaagtgt
    32521 atgtgtatgc caaaattcag tcacctcatt tattattttt tgtgctggaa gtgttgtggc
    32581 aacttcaata ggtatgtttg atttttgtaa aaagtatttc accaagtgat agccacatgc
    32641 ataaccggca gcatgagata agccaacgat aggcctacct tgaagtttat taatatcatc
    32701 accatagaga taaggcatcg attcaaatat atgctttaaa tgtaaatgat tataaatagt
    32761 atttttaatt tttacgttat cacgactcca attagtattt gttacccacg gtccaatatg
    32821 cgctttacca tacaatgatt ctacatagtt ttcagctaat ccttctgcaa taatcaattc
    32881 aatcaaactt ccgccatccc aatcaatata ttgatagcgc atattatgat ttacttcatg
    32941 tgcaattaag cttttcatag aattaattgt acttgtactc ggcactaaat aaatcataat
    33001 ataacctggt atgccaccat caccaccacg atttttattt agatacataa gtggtttttg
    33061 gctatctcca agtaatactg tgaaatgata gttagaaact tgagatgaga tactataatt
    33121 tgcaaattga tctatagcaa cttttaaata tttttcacaa ttaatccaga aatcattatt
    33181 caggtattgt attgacattt ggtcagtttc aaccagttct tcgggagact tatgaaatac
    33241 atctaaaagt tgaatcgcac tcattgtctg cttgtcatca ttatgaatag gaatctgctg
    33301 cacctcaaat ttctttttaa aaggtactaa tatttcttta gtgaaaattg aatcacgttc
    33361 gtttaatggt gccttgagta ttttcttata gacggaatct gatctaataa tattgatttt
    33421 atacatgata aacctcctta cgctgtcagc ataaagggta acgtaacgtg attttcaagc
    33481 agtaattgta actaattgaa aaaaattaag aaaagtatgt gagcgttcct taataatatg
    33541 attaaaatga tgacaaaata gtgtctaaat gcatcgtaaa gggacattgt ataggggaaa
    33601 tcacaccata aataagggaa aatccttatg ttcacttttt cacaatcata ataaaatata
    33661 tatgtagtca atactttgtc tatattgaat gttttcatat aaatgaaagc atttttaaat
    33721 aacattgacc tctaacatat aggcagagta ttgatatcta ttaaaaaata aatgattttg
    33781 gtgaaggtga aacgtatgta caaaacaaaa ggtggctttc aacttacatt acaaacatta
    33841 agtttagtgg ttggatttat ggcttggagt attattgctc ctttaatgcc ttttattaaa
    33901 caggatgtca atgtaactga aggtcaaata tcaatcattt tagcgatacc agttattttg
    33961 ggatcagtgc tccgtgtgcc atttggttat ttaacaaata ttgttggtgc taaatgggta
    34021 ttctttacaa gttttatcgt attgttattc ccgatatttt tcttgagcca agcacaaacg
    34081 ccggggatgt taatggcatc aggatttttc cttggcgtag gtggcgcaat tttctctgtt
    34141 ggtgttacat cagttcctaa atatttccct aaagaaaaag taggtctagc aaatggtatt
    34201 tatggtatgg ggaatatcgg tacagcagtt tcttcatttt tagcaccacc gatagcgggt
    34261 attattggtt ggcaaacaac agttagaagt tacttaatta ttatcgcttt atttgcatta
    34321 attatgttca tttttggtga cacacaagaa cgtaaaatta aagtgccatt aatggctcaa
    34381 atgaaaacat tatctaaaaa ctacaaatta tattacttaa gttattggta tttcattact
    34441 tttggtgctt ttgttgcatt tggtattttc ttacctaact acttagtaaa tcattttgga
    34501 attgacaaag tagatgctgg tattcgttca ggtgtattca ttgcgctggc aacattcttg
    34561 agaccaatag gtggtatact aggtgataaa tttaatgcag ttaaagtact gatgattgat
    34621 tttgttatta tgattatcgg tgccgttatt ttaggtattt cagaccatat cgcattattc
    34681 actgtaggct gtttaacaat aagtatttgt gcaggtattg gtaacggctt aatttttaaa
    34741 ttagtaccat catacttctc aaatgaagca ggatcagcaa atggtatcgt atcaatgatg
    34801 ggtggtttag gaggattctt cccaccgttg gtcatcacat acgtagctaa tttaacaggt
    34861 tcaagccatt tagcatttat tttcttagcg gtattcggct gcattgcatt atttacaatg
    34921 cgccatttat atcaaaaaga atatggttca ttgaaacaca gttgatatgt aatacgaagc
    34981 attcttaaat ttaaatgaca aagccttaat atcatgcgca atattcgtag catgatatta
    35041 aggctttagt agtgtattca ttttaaattt aactatgaaa ttggaataga tgttgatgaa
    35101 gtagtgtcat tgcttggttt gattttaggc agggtaatag ttaatagccc attttcaaaa
    35161 ctagcagtaa tatgttgttt atcaacagct tcaaaatcaa attgacgcat taatgattcg
    35221 aagttacgct catctaaaat gagttgttca gatttgtgtt ttgcgtttct agtagcttga
    35281 atagtgagcg tattattatt gaaatcgata ctaatatctt ctttatttac acctgctagt
    35341 tcagcttcta agtaatataa ttcgtctgtt tcatatatat tcgttacaaa tgaaggtgtt
    35401 gaaaagtaat taaatacttg tttacctaaa tctttaaatg tatcacttgg attaccgtta
    35461 aaaaagtttt gattctcgaa ttgattgaag ttcaatatca tcacttccat tatataaatt
    35521 tgtattacaa agccattata tgagtagtat taaaaaagat aaagtaaaag gggagataaa
    35581 aagttataaa tgggtagatt tgtgcctgat aaggaatcag ggcaaaagag ctgagcatcg
    35641 agatttatac aagcaataaa gataatgaat aaacatagcg atgcatactt ctgcccatca
    35701 ccttatgata gggagttact ttttgtcgga attgtcgaaa tttttcgaaa caaaattccg
    35761 caaattatta acaatgtctg atgcttctcg ttctgaaatg ttgaattcat taaatacttt
    35821 aacagaaatt tcagcaagag gactttttat tgctttacct tgctctgtta gagaaatttg
    35881 taggtttctt tcatctttct cttcacgtgt tcgaacaacg taatctttct tttctaattt
    35941 ctttagtaat ggtgtcagtg ttccagaatc taagaataca cgttcaccta attttttgat
    36001 gttaagtttt tcatcatttt caatcgccat taaaacaatg taaccagtat aggttaaatc
    36061 ataatcctta agatagtttg tgtatttttt aattatttct tttgaagaaa cataaaataa
    36121 aaaacacaac tgtttgctaa gatagctgtt ttctacatac atccaatcac tccttgttaa
    36181 aataaacaat attatgaagt gtaatagttg tcaagtactg atttcatcgc aattatcgaa
    36241 ttgtctataa ttgaatttaa atgttaaata atgcaaaaca tatcaatatc ttagtatttt
    36301 catcggtaat gactgatatg actgattttt taaattgaaa aaaatggaat tgtatcattc
    36361 ttaattgtta aaagtagtca attattttga tagatagtaa aatgaaattt gttattaaat
    36421 tttttcaaag catcgtgtat gtaattcgat ttctataata atattgagaa gaaaaaaatt
    36481 gttacaatct ggtaaaaact ctttattaaa taaattgatt cgttcatact gaatagataa
    36541 gcaaaaagga gttacataat gaagaagaaa aaaaacgtga ttaaagttat cattatatta
    36601 tttatttcat taattgttgc tgtagcattt ttctttggtc tgaaaacata tcaaggccat
    36661 aagaatattc aacttattga cagttacttg gaagagaaaa gtctaaaaga taaaattaaa
    36721 tcagaaaaaa cagagtatag tgctaaaaaa ggtctcttct ataaggaagt tacatttaaa
    36781 gatgaacctg gtgtaactta tgttgtgcag cctatcagta ctaataaagg attatttgtt
    36841 gaaggctttg atacagaaac taagaaaagt ttgaaaactg caaagcataa atatttcaat
    36901 caaaattata aaccatcaaa atagtgaagc gtataactgg tataacagtt tagtgccttc
    36961 aattttaatt atttgaggta aacagttttt gtatggaaat tagtgatttt tgacatctat
    37021 aaaagataaa tattttaatt ttttatagat aattatcaat tttctgatat aattgagtga
    37081 tgtcagatga aggggagttt gtactatggc tctattcaag agaaaaatta gcctacctat
    37141 gcaagttgtt attgcattag tgttaggtgt tgtcgtagga cttttattat atggacaaga
    37201 aaacgtagca aattacatta aaccatttgg tgacgtattt ttaaatttaa ttaaaatgat
    37261 cgttatacca gttgtatttt gctcgctagc gctttctatt tcgaacgttg gggaatcgaa
    37321 aactgtaggg cgttatggct ggaaaacaat tttatacttt gaaattatta caacaatcgc
    37381 aataggttta gggattatct tcggtaacct atttaaacca ggtgctggat tagacccaac
    37441 aaaattacct aaaggtgata tttctaaata tcaatcaact gcacatgcag cagaacaatc
    37501 tacatatgga aatcatttta ttgataccat tgtacatatt attccgacaa acttttttga
    37561 agctttaaat aagggtgaat tattacctat tatcttcttc gcagtattct ttggattagg
    37621 attagctgca gtaggtaaaa aagcagaacc agttaaagaa tttttaagcg gatcgcttga
    37681 agctgtgttc tggatgatta ataaaatttt aaaattagca ccacttggag tgtttgcatt
    37741 catttgtact acaattatta catttggtgc atccgcatta ttaccactat taaaattagt
    37801 attagttgtt gtctttgcaa tggtgttctt tgtattcgct atactaggac tagttgcatg
    37861 gatgtgtggt attaatatca tgaatattat tagaatcttg aaaagtgaat tgcttttagc
    37921 attttctaca tcaagttcgg aagctgtact tcctgtaatg atgaagaaaa tggaaaactt
    37981 cggttctcca aaagaaatta cttcttttgt tataccaatt ggttatacgt ttaacttaga
    38041 cggatcagca ctttatcaat ctattgcagc attattcgtt gcacagatgt atggaatgca
    38101 cttaacatta tcagagcaaa ttgtgttgat gttaacatta atgattacgt ctaaaggtat
    38161 ggcggcagta ccaggaactt caatcgttgt tttattaaca acattaggtg ccatgggctt
    38221 accggcacaa ggtttagcat taattattgg tgttgaccgt atcttagata tggtacgtac
    38281 atgtgtaaac gttattggta acgcattatc aacaatcgtt atagctaaat gggaaaacgt
    38341 atatgacaaa gcaaaaggtc aagaatattt aaaatcaatt taaaaaatac tatctgacat
    38401 ttaaagcccc ttacaacctt tggttgttag gggcttttat gcatgcgcta aagcgcaggc
    38461 gaaccgaaac gaagtgacct caggttgtta ggggctttta tgcatgcgca aagcgcaggc
    38521 gaaccgaaat gaaggcaacc tcaggttgtt aggggctttt atgcatgcgc taaagcgcag
    38581 gcgaaccgaa acgaagtgac ctctggttgt taggggcttt tatgcatgcg ctaaagcgca
    38641 ggcgaaccga agcgcagtga cctcaggttg ttaggggctt ttatgcatgc gcaaagcgca
    38701 ggcgaaccga aacgaagtga cctctggttg ttaggggctt ttatgcatgc gcaaagcgca
    38761 ggcgaaccgg aaatagactg acacagtaat tcttaaaaag cagcagtaag ataattttca
    38821 attagaaaac atcttactgc tgcttttaat atcttatata ttattcaaaa ttaaagctta
    38881 attagtgttt catgtgcatt ttgcccatgt catgaatttt catcattaaa ccatgtggta
    38941 catcgtcatg atcaactttt tttactttaa caattttatc agaatctgct aatttataaa
    39001 caattacaaa atcacctttt ttaactgaaa cgtctgcatc tgaaggtaat ttaacgttct
    39061 tctcaatgct ttcatctttt tcactaatca ttttttcaat tgtagcattg tctttcataa
    39121 ttccataata tgtatctttc tttccaccag tcatcatcat gattactagt acaatacata
    39181 caatcaacat gatggcaatt aaactaatac caagaccaaa ccctttttta tttttcacgg
    39241 ttcatcaatc tccttaaatg tagttaattc tgttatacct aaaagtacaa cagtttgcaa
    39301 atgcagtatt tatattacat aaaattaatt taaaaagaca caccttaatc acaat
//
LOCUS       DAPSKH010000019        38384 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPSKH010000019 DAPSKH010000000
VERSION     DAPSKH010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38384)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38384)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38384
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.019"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            80..1417
                     /locus_tag="RPH49_001073"
     CDS             80..1417
                     /locus_tag="RPH49_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HDY5124250.1"
                     /translation="MKQPILNKLESLNQEEAISLHVPGHKNMTIGHLSQLSMTMDKTE
                     IPGLDDLHHPEEVILESMKQVEKHSDYDAYFLVNGTTSGILSVIQSFSQKKGDILMAR
                     NVHKSVLHALDISQQEGHFIETHQSPLTNHYNKVNLSRLNNDGHKLAVLTYPNYYGET
                     FNVEEVIKSLHQLNIPVLIDEAHGAHFGLQGFPDSTLNYQADYVVQSFHKTLPALTMG
                     SVLYIHKNAPYRETIIEYLSYFQTSSPSYLIMASLESAAEFYKTYDSTVFFDKRAQLI
                     ECLEKKGFEMLQVDDPLKLLIKYEGFTGHDIQNWFMNAHIYLELADDYQALAILPLWH
                     HDDTYLFDSLLRKIEDMILPKKSVSKVKQTQLLTTEGNYKPKRFEYVTWCDLKKAKGK
                     VLARHIVPYPPGIPIIFKGETITENMIELVNEYLETGMIVEGIKNNKILVEDE"
     gene            1419..2036
                     /locus_tag="RPH49_001074"
     CDS             1419..2036
                     /locus_tag="RPH49_001074"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDY5124251.1"
                     /translation="MSAFITFEGPEGSGKTTVINEVYHRLVKDYDVIMTREPGGVPTG
                     EEIRKIVLEGNDMDIRTEAMLFAASRREHLVLKVIPALKEGKVVLCDRYIDSSLAYQG
                     YARGIGVEEVRALNEFAINGLYPDLTIYLNVSAEVGRERIIKNSRDQNRLDQEDLKFH
                     EKVIEGYQEIIHNESQRFKSVNADQPLENVVEDTYQTIIKYLEKI"
     gene            2064..2393
                     /locus_tag="RPH49_001075"
     CDS             2064..2393
                     /locus_tag="RPH49_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019467733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDY5124252.1"
                     /translation="MKMIIAIVQDQDSQELADQLVKNNFRATKLATTGGFLRAGNTTF
                     LCGVNDDRVDEILSVINQTCGNREQLVSPITPMGGSADSYIPYPVEVEVGGATVFVMP
                     VDAFHQF"
     gene            2607..3533
                     /locus_tag="RPH49_001076"
     CDS             2607..3533
                     /locus_tag="RPH49_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDY5124253.1"
                     /translation="MDEQQQLTNAYHSNKLSHAYLFEGDDAQTMKQVAINFAKLILCQ
                     TDSQCETKVSTYNHPDFMYISTTENAIKKEQVEQLVRHMNQLPIESTNKVYIIEDFEK
                     LTVQGENSILKFLEEPPDNTIAILLSTKPEQILDTIHSRCQHVYFKPIDKEKFINRLV
                     EQNMSKPVAEMISTYTTQIDNAMALNEEFDLLALRKSVIRWCELLLTNKPMALIGIID
                     LLKQAKNKKLQSLTIAAVNGFFEDIIHTKVNVEDKQIYSDLKNDIDQYAQKLSFNQLI
                     LMFDQLTEAHKKLNQNVNPTLVFEQIVIKGVS"
     gene            3534..4337
                     /locus_tag="RPH49_001077"
     CDS             3534..4337
                     /locus_tag="RPH49_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDY5124254.1"
                     /translation="MPNVIGVQFQKAGKLEYYTPNDIQVDIDDWVVVESKRGIEIGIV
                     KNPLMDIAEEDVVLPLKNIIRVADDKDIDKFNCNERDAENALILCKDIVREQGLDMRL
                     VNCEYTLDKSKVIFNFTADDRIDFRKLVKILAQHLKTRIELRQIGVRDEAKLLGGIGP
                     CGRSLCCSTFLGDFEPVSIKMAKDQNLSLNPTKISGACGRLMCCLKYENDYYEEVRAQ
                     LPDIGEAIETPDGNGKVVALNILDISMQVKLEGHEQPLEYKLEEIETMH"
     gene            4354..4701
                     /gene="yabA"
                     /locus_tag="RPH49_001078"
     CDS             4354..4701
                     /gene="yabA"
                     /locus_tag="RPH49_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499035.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDY5124255.1"
                     /translation="MDRNEIFEKIMRLEMNVNQLSKETSELKALAVELVEENVALQLE
                     NDNLKKVLGNDEPTTIDTANSKPAKAVKKPLPSKDNLAILYGEGFHICKGELFGKHRH
                     GEDCLFCLEVLSD"
     gene            4975..5700
                     /locus_tag="RPH49_001079"
     CDS             4975..5700
                     /locus_tag="RPH49_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDY5124256.1"
                     /translation="MLKENERFDQLIKEDFSIIQNDDVFSFSTDALLLGHFTKPRTKD
                     IVLDLCSGNGVIPLLLFAKHPRHIEGVEIQKTLVDMARRTFQFNDVDEYITMHHMDLK
                     NVTKVFKPSQYTLVTCNPPYFKENQQHQHQKEAHKIARHEIMCTLEDCMIAARHLLKE
                     GGRLNMVHRAERLMDVLFEMRKVNIEPKKVVFIYSKVGKSAQTIVVEGRKGGNQGLEI
                     MPPFYIYNEDGNYSEEMKEVYYG"
     gene            5693..5941
                     /locus_tag="RPH49_001080"
     CDS             5693..5941
                     /locus_tag="RPH49_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDY5124257.1"
                     /translation="MDSHFVYIVKCSDGSLYTGYAKDVNARVEKHNRGQGAKYTKVRR
                     PVHLVYQEMYETKSEALKREYEIKTYTRQKKLRLIKER"
     gene            5943..6782
                     /gene="rsmI"
                     /locus_tag="RPH49_001081"
     CDS             5943..6782
                     /gene="rsmI"
                     /locus_tag="RPH49_001081"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDY5124258.1"
                     /translation="MAVLYLVGTPIGNLADITYRAVDVLKRVDMIACEDTRVTSKLCN
                     HYDIPTPLKSYHEHNKDKQTAFIIEQLELGLDVALVSDAGLPLISDPGYELVVAAREA
                     NIKVETVPGPNAGLTALMASGLPSYVYTFLGFLPRKEKEKSAVLEQRMHENSTLIIYE
                     SPHRVTDTLKTIAKIDATRQVSLGRELTKKFEQIVTDDVTQLQALIQQGDVPLKGEFV
                     ILIEGAKANNEISWFDDLSINEHVDHYIQTSQMKPKQAIKKVAEERQLKTNEVYNIYH
                     QIS"
     gene            7067..9040
                     /gene="metG"
                     /locus_tag="RPH49_001082"
     CDS             7067..9040
                     /gene="metG"
                     /locus_tag="RPH49_001082"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDY5124259.1"
                     /translation="MAKETFYITTPIYYPSGNLHIGHAYSTVAGDVIARYKRMQGYDV
                     RYLTGTDEHGQKIQEKAQKAGKTEIEYLDEMIAGIKQLWAKLEISNDDFIRTTEERHK
                     HVVEQVFERLLKQGDIYLGEYEGWYSVPDETYYTESQLVDPQYENGKIIGGKSPDSGH
                     EVELVKEESYFFNISKYTDRLLEFYDQNPDFIQPPSRKNEMINNFIKPGLADLAVSRT
                     SFNWGVHVPSNPKHVVYVWIDALVNYISALGYLSDDESLFNKYWPADIHLMAKEIVRF
                     HSIIWPILLMALDLPLPKKVFAHGWILMKDGKMSKSKGNVVDPNILIDRYGLDATRYY
                     LMRELPFGSDGVFTPEAFVERTNFDLANDLGNLVNRTISMVNKYFDGELPAYQGPLHE
                     LDEEMEAMALETVKSYTESMESLQFSVALSTVWKFISRTNKYIDETTPWVLAKDDSQK
                     DMLGNVMAHLVENIRYAAVLLRPFLTHAPKEIFEQLNINNPQFMEFSSLEQYGVLTES
                     IMVTGQPKPIFPRLDSEAEIAYIKESMQPPATEEEKEEIPSKPQIDIKDFDKVEIKAA
                     TIIDAEHVKKSDKLLKIQVDLDSEQRQIVSGIAKFYTPDDIIGKKVAVVTNLKPAKLM
                     GQKSEGMILSAEKDGVLTLVSLPSAIPNGAVIK"
     gene            9071..9844
                     /locus_tag="RPH49_001083"
     CDS             9071..9844
                     /locus_tag="RPH49_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDY5124260.1"
                     /translation="MLIDTHVHLNDEQYDDDLSEVITRAREAGVDRMFVVGFNKSTIE
                     RAMKLIDEYDFLYGIIGWHPVDAIDFTEEHLEWIESLAQHPKVIGIGEMGLDYHWDKS
                     PADVQKEVFRKQIALAKRLKLPIIIHNREATQDCIDILLEEHAEEVGGIMHSFSGSPE
                     IADIVTNKLNFYISLGGPVTFKNAKQPKEVAKHVSMERLLVETDAPYLSPHPYRGKRN
                     EPARVTLVAEQIAELKGLSYEEVCEQTTKNAEKLFNLNS"
     gene            10011..10547
                     /gene="rnmV"
                     /locus_tag="RPH49_001084"
     CDS             10011..10547
                     /gene="rnmV"
                     /locus_tag="RPH49_001084"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDY5124261.1"
                     /translation="MKINEFIVVEGRDDTERVKRAVECDTIETNGSAINEQTLEVIRN
                     AQQSRGVIVLTDPDFPGDKIRSTITEHVKGVKHAYIDREKAKNKKGKIGVEHADLIDI
                     KEALMHVSSPFDEAYESIDKSVLIELGLIVGKDARRRREILSRKLRIGHSNGKQLLKK
                     LNAFGYTEADVRQALEDE"
     gene            10558..11451
                     /gene="rsmA"
                     /locus_tag="RPH49_001085"
     CDS             10558..11451
                     /gene="rsmA"
                     /locus_tag="RPH49_001085"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDY5124262.1"
                     /translation="MLDNKDIATPSRTRALLDKYGFNFKKSLGQNFLIDVNIINNIID
                     ASDIDAQTGVIEIGPGMGSLTEQLARHAKRVLAFEIDQRLIPVLNDTLSPYDNVTVIN
                     EDILKANIKEAVENHLQDCEKIMVVANLPYYITTPILLNLMQQDIPIDGYVVMMQKEV
                     GERLNAEVGSKAYGSLSIVVQYYTETSKVLTVPKSVFMPPPNVDSIVVKLMQRTEPLV
                     TVDNEEAFFKLAKAAFAQRRKTINNNYQNYFKDGKQHKEVILQWLEQAGIDPRRRGET
                     LSIQDFAKLYEEKKKFPQLEN"
     gene            11551..11814
                     /locus_tag="RPH49_001086"
     CDS             11551..11814
                     /locus_tag="RPH49_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDY5124263.1"
                     /translation="MPKSILDIKNSIDCHVGNRIVLKANGGRKKTIKRSGILKETYPS
                     VFIVELDQDKHNFERVSYTYTDVLTENVQVSFEEDNHHESIAH"
     gene            12123..12971
                     /locus_tag="RPH49_001087"
     CDS             12123..12971
                     /locus_tag="RPH49_001087"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDY5124264.1"
                     /translation="MIYETAPAKINFTLDTLFKRNDGYHEIEMIMTTVDLNDRLTFHK
                     RKDRKIVVEIEHNYVPSNHKNLAYRAAQLFIEQYQLKQGVTISIDKEIPVSAGLAGGS
                     ADAAATLRGLNRLFDIGASLEELALLGSKIGTDIPFCIYNKTALCTGRGEKIEFLNKP
                     PSAWVILAKPNLGISSPDIFKLINLDKRYDVHTKMCYEALENRDYQQLCQSLSNRLEP
                     ISVSKHPQIDKLKNNMLKSGADGALMSGSGPTVYGLARKESQAKNIYNAVNGCCNEVY
                     LVRLLG"
     gene            12985..13809
                     /gene="purR"
                     /locus_tag="RPH49_001088"
     CDS             12985..13809
                     /gene="purR"
                     /locus_tag="RPH49_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDY5124265.1"
                     /translation="MRYKRSERIVFMTQYLMNHPNKLIPLTFFVKKFKQAKSSISEDV
                     QIIKNTFQKEKLGTVITTAGASGGVTYKPMMSKEEATEVVNEVITLLEEKERLLPGGY
                     LFLSDLVGNPSLLNKVGKLIASIYMEEKLDAVVTIATKGISLANAVANILNLPVVVIR
                     KDNKVTEGSTVSINYVSGSSRKIETMVLSKRTLAENSNVLVVDDFMRAGGSINGVMNL
                     MNEFKAHVKGVSVLVESKEVKQRLIEDYTSLVKLSDVDEYNQEFNVEPGNSLSKFS"
     gene            13826..14206
                     /locus_tag="RPH49_001089"
     CDS             13826..14206
                     /locus_tag="RPH49_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDY5124266.1"
                     /translation="MKIINTTRLPEALGPYSHATVVNGMVYTSGQIPLNIDGHIVSAD
                     VQAQTKQVLENLKVVLEEAGSDLDSVAKATIFIKDMNDFQKINEVYGQYFNEHKPARS
                     CVEVARLPKDVKVEIELVSKIKEL"
     gene            14278..14580
                     /gene="spoVG"
                     /locus_tag="RPH49_001090"
     CDS             14278..14580
                     /gene="spoVG"
                     /locus_tag="RPH49_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation regulator SpoVG"
                     /protein_id="HDY5124267.1"
                     /translation="MKVTDVRLRKIQTDGRMKALVSITLDEAFVIHDLRVIEGNSGLF
                     VAMPSKRTPDGEFRDIAHPINSDMRQEIQDAVMKVYDETDEVVPDKNATSEDSEEA"
     gene            14770..14901
                     /locus_tag="RPH49_001091"
     CDS             14770..14901
                     /locus_tag="RPH49_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124268.1"
                     /translation="MRLNDARIFEVRKKLFLKLQRIKNNAFYMLKEYCRLNYNNDEV"
     gene            14924..16276
                     /gene="glmU"
                     /locus_tag="RPH49_001092"
     CDS             14924..16276
                     /gene="glmU"
                     /locus_tag="RPH49_001092"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDY5124269.1"
                     /translation="MRRHAIILAAGKGTRMKSKKYKVLHEVAGKPMVEHVLESVKGSG
                     VDQVVTIVGHGAESVKGHLGERSLYSFQEEQLGTAHAVRMAKSHLEDKEGTTIVVCGD
                     TPLITKETLETLIAHHEDANAQATVLSASIQQPYGYGRIVRNASGRLERIVEEKDATQ
                     AEKDINEISSGIFAFNNKTLFEKLTQVKNDNAQGEYYLPDVLSLILNDGGIVEVYRTN
                     DVEEIMGVNDRVMLSQAEKAMQRRTNHYHMLNGVTIIDPDSTYIGPDVTIGSDTVIEP
                     GVRINGRTEIGEDVVIGQYSEINNSTIENGACIQQSVVNDASVGANTKVGPFAQLRPG
                     AQLGADVKVGNFVEIKKADLKDGAKVSHLSYIGDAVIGERTNIGCGTITVNYDGENKF
                     KTIVGKDSFVGCNVNLVAPVTIGDDVLVAAGSTITDDVPNDSLAVARARQTTKEGYRK
                     "
     gene            16423..17388
                     /locus_tag="RPH49_001093"
     CDS             16423..17388
                     /locus_tag="RPH49_001093"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDY5124270.1"
                     /translation="MLNNEYKNSSLKIFSLKGNEALAQEVADQVGIELGKCSVKRFSD
                     GEIQINIEESIRGCDVFIIQPTSYPVNLHLMELLIMIDACKRASAATINIVVPYYGYA
                     RQDRKARSREPITAKLVANLIETAGATRMIALDLHAPQIQGFFDIPIDHLMGVPILAK
                     HFKDDPNINPEECVVVSPDHGGVTRARKLADILKTPIAIIDKRRPRPNVAEVMNIVGE
                     IEGRTAIIIDDIIDTAGTITLAAQALKDKGAKEVYACCTHPVLSGPAKERIENSAIKE
                     LIVTNSIHLDEDRKPSNTKELSVAGLIAQAIIRVYERESVSVLFD"
     gene            17538..18191
                     /locus_tag="RPH49_001094"
     CDS             17538..18191
                     /locus_tag="RPH49_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDY5124271.1"
                     /translation="MASLKSIIRQGKQTRSDLKQLRKSGKVPAVVYGYGTKNVSVKVD
                     EVEFIKVIREVGRNGVIELGVGSKTIKVMVADYQFDPLKNQITHIDFLAINMSEERTV
                     EVPVQLVGEAVGAKEGGVVEQPLFNLEVTATPDNIPEAIEVDITELNINDSLTVADVK
                     VTGDFKIENDSAESVVTVVAPTEEPTEEEIEAMEGEQQTEEPEVVGESKEDEEKTEE"
     gene            18502..19074
                     /locus_tag="RPH49_001095"
     CDS             18502..19074
                     /locus_tag="RPH49_001095"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDY5124272.1"
                     /translation="MKCIVGLGNIGKRFELTRHNIGFEVVDYILEKNNFSLDKQKFKG
                     AYTIERMNGDKVLFIEPMTMMNLSGEAVAPIMDYYNVNPEDLIVLYDDLDLEQGQVRL
                     RQKGSAGGHNGMKSIIKMLGTDQFKRIRIGVGRPTNGMTVPDYVLQRFSNDEMVTMEK
                     VIEHAARAIEKFVETSRFDHVMNEFNGEVK"
     gene            19074..22580
                     /gene="mfd"
                     /locus_tag="RPH49_001096"
     CDS             19074..22580
                     /gene="mfd"
                     /locus_tag="RPH49_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDY5124273.1"
                     /translation="MTILTTLIKEDNHFQDLNQVFGQANTLVTGLSPSAKVTMIAEKY
                     AQSNQQLLLITNNLYQADKLETDLLQFIDAEELYKYPVQDIMTEEFSTQSPQLMSERI
                     RTLTALAQGKKGLFIVPLNGLKKWLTPVEMWQNHQMTLRVGEDIDVDQFLNKLVNMGY
                     KRESVVSHIGEFSLRGGIIDIFPLIGEPIRIELFDTEIDSIRDFDVETQRSKDNVEEV
                     DITTASDYIITEEVISHLKEELKTAYENTRPKIDKSVRNDLKETYESFKLFESTYFDH
                     QILRRLVAFMYETPSTIIEYFQKDAIIAVDEFNRIKETEESLTVESDSFISNIIESGN
                     GFIGQSFIKYDDFETLIEGYPVTYFSLFATTMPIKLNHIIKFSCKPVQQFYGQYDIMR
                     SEFQRYVNQNYHIVVLVETETKVERMQAMLSEMHIPSITKLHRSMSSGQAVIIEGSLS
                     EGFELPDMGLVVITERELFKSKQKKQRKRTKAISNAEKIKSYQDLNVGDYIVHVHHGV
                     GRYLGVETLEVGQTHRDYIKLQYKGTDQLFVPVDQMDQVQKYVASEDKTPKLNKLGGS
                     EWKKTKAKVQQSVEDIAEELIDLYKEREMAEGYQYGEDTAEQTTFELDFPYELTPDQA
                     KSIDEIKDDMQKSRPMDRLLCGDVGYGKTEVAVRAAFKAVMEGKQVAFLVPTTILAQQ
                     HYETLIERMQDFPVEIQLMSRFRTPKEIKQTKEGLKTGFVDIVVGTHKLLSKDIQYKD
                     LGLLIVDEEQRFGVRHKERIKTLKHNVDVLTLTATPIPRTLHMSMLGVRDLSVIETPP
                     ENRFPVQTYVLEQNMSFIKEALERELSRDGQVFYLYNKVQSIYEKREQLQMLMPDANI
                     AVAHGQMTERDLEETMLSFINNEYDILVTTTIIETGVDVPNANTLIIEDADRFGLSQL
                     YQLRGRVGRSSRIGYAYFLHPANKVLTETAEDRLQAIKEFTELGSGFKIAMRDLNIRG
                     AGNLLGKQQHGFIDTVGFDLYSQMLEEAVNEKRGIKEPESEVPEVEVDLNLDAYLPTE
                     YIANEQAKIEIYKKLRKTETFDQIIDIKDELIDRFNDYPVEVARLLDIVEIKVHALHS
                     GITLIKDKGKIIDIHLSVKATENIDGEVLFKATQPLGRTMKVGVQNNAMTITLTKQNQ
                     WLDSLNFLVKCIEESMRISDEA"
     gene            22570..24096
                     /locus_tag="RPH49_001097"
     CDS             22570..24096
                     /locus_tag="RPH49_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDY5124274.1"
                     /translation="MKHKEAFNGVVVLTAALIVIKILSAVYRIPYQNILGDTGLYAYQ
                     QVYPIVALGMILSMNAIPSAITQNIGKYHSDEAYAKAVAYIQLVGILIFIAIFVFANN
                     IAHMMGDGHLTPMIQAASLSFIFIGMLGVLRGYYQSANNMTVPAISQVIEQVIRVGII
                     IVTIVIFVDRGWTIYEAGTIAILASTIGFLGSSIYLVAHRPFKFKMVNNTAKIVWKQF
                     ALSVLIFAISQLIVILWQVIDSVTIIKSLQAIRVPFDVAITEKGVYDRGASFIQMGLI
                     VTTTFSFALIPLLSDAIKMNNQVLMNRYANASLKITILISTAAGIGLINLLPLMNGVF
                     FKTNDLTLTLSVYMITVICVSLIMMDMALLQAQHAVRPIFVGMTAGLVIKFILNIILI
                     RLSGIIGASISTVVSLIIFGTIIHIAVTRKYHLHAMRRFFINVVLGMVFMSIVVQCVL
                     NIVTTHGRITGLIELLCAAVLGIIALFFYIFRFNVLTYKELTYLPFGSKLYQIKKGRR
                     "
     gene            24096..25289
                     /locus_tag="RPH49_001098"
     CDS             24096..25289
                     /locus_tag="RPH49_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDY5124275.1"
                     /translation="MAHTITIVGLGNYGIDDLPLGIYKFLKTQDKVYARTLDHLVIES
                     LQDELTFQSFDHVYEAHDQFEDVYNDIVAQLVEDANEKDIVYAVPGHPRVAETTTVKL
                     LALAKDNTDIDVKVLGGKSFIDDVFEAVNVDPNDGFTLLDATSLQEVTLNVRTHTLIT
                     QVYSAMVAANLKITLMERYPDDYPVQIVTGARSDGADNVVTCPLYELDHDENAFNNLT
                     SVFVPKIITSTYLYHDFDFATEVIDTLVDEDKGCPWDKVQTHETLKRYLLEETFELFE
                     AIDNEDDWHMIEELGDILLQVLLHTSIGKKEGYIDIKEVITSLNAKMIRRHPHIFGDA
                     NAETIDDLKEIWSKAKDAEGKQPRVKFEKVFAEHFLNLYEKTKDKSFDEAALKQWLEK
                     GESNT"
     gene            25286..25549
                     /locus_tag="RPH49_001099"
     CDS             25286..25549
                     /locus_tag="RPH49_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDY5124276.1"
                     /translation="MRLDKYLKVSRLIKRRTLAKEVSDQGRITINGNVAKAGSDVKVE
                     DVLTIRFGQKLVTVKVTALNEHASKDNAKGMYEIVEERRLEEA"
     gene            25567..25959
                     /locus_tag="RPH49_001100"
     CDS             25567..25959
                     /locus_tag="RPH49_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDY5124277.1"
                     /translation="MKNKVEHIENQYTSQENKKKQRQKMKMRVVRRRITVFAGVLLAI
                     IVVLSILLVVQKHRNDIDAQERKAKEAQFQKQQNEEIALKEKLNNLNDKDYIEKIARD
                     DYYLSNKGEVIFRLPEDKDSSSSKSSKK"
     gene            26064..26465
                     /locus_tag="RPH49_001101"
     CDS             26064..26465
                     /locus_tag="RPH49_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDY5124278.1"
                     /translation="MSIEVGNKLKGKVTGIKKFGAFVELPEGKSGLVHISEVADNYVE
                     NVEEHLSVGDEVDVKVLSIADDGKISLSIKKAKDRPRRQHTSKPSHQKPVQKAEDFEK
                     KLSNFLKDSEDKLTSIKRQTESRRGGKGSRR"
     gene            26645..27940
                     /gene="tilS"
                     /locus_tag="RPH49_001102"
     CDS             26645..27940
                     /gene="tilS"
                     /locus_tag="RPH49_001102"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDY5124279.1"
                     /translation="MQLNSNGWHVDDHIVVAVSTGIDSMCLLYQLLNDYKDSYRKLTC
                     LHVNHGVRSASIEEARFLEVYCERHHIDLHIKKLDLSHSLDRNNSIQNEARIKRYEWF
                     DEMMNVLEADVLLTAHHLDDQLETIMYRIFNGKSTRNKLGFDELSKRKGYQIYRPLLA
                     VSKKEIKQFQERYHIPYFEDESNKDNKYVRNDIRNRIIPAIDENNQLKVSHLLKLKQW
                     HDEQYDILQYSAKQFIQEFVKFDEQSKYLEVSRQAFNNLPNSLKMVVLDCLLSKYYEL
                     FNISAKTYEEWFKQFSSKKAQFSINLTDKWIIQIAYGKLIIMAKNNGDTYFRVQTIEK
                     PGNYIFNKYRLEIHSNLPKCLFPLTVRTRQSGDTFKLNGRDGYKKVNRLFIDCKVQQW
                     VRDQMPIVLDKQQRIIAVGDLYQQQTIKQWIIISKNGDE"
     gene            27945..28484
                     /gene="hpt"
                     /locus_tag="RPH49_001103"
     CDS             27945..28484
                     /gene="hpt"
                     /locus_tag="RPH49_001103"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDY5124280.1"
                     /translation="MHNDLKEVLLTEEDIQNICKELGAQLTKDYQGKPLVCVGILKGS
                     AMFMSDLIKRIDTHLSIDFMDVSSYHGGTESTGEVQIIKDLGSSIENKDVLIIEDILE
                     TGTTLKSITELLQSRKVNSLEIVTLLDKPNRRKADIEAKYVGKKIPDEFVVGYGLDYR
                     ELYRNLPYIGTLKPEVYSN"
     gene            28741..30834
                     /gene="ftsH"
                     /locus_tag="RPH49_001104"
     CDS             28741..30834
                     /gene="ftsH"
                     /locus_tag="RPH49_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDY5124281.1"
                     /translation="MQKAFRNVLVIVIIGVIIFGLFSYLNGNGNMPKQLTYNQFTEKL
                     EKGDLKTLEIQPQQNVYMVSGKTKNDEDYSSTILYNNEKELQKITDAAKKQNGVKLTI
                     KEEEKQSVFVSILSTLIPVVVIALLFIFFLSQAQGGGSGGRMMNFGKSKAKMYDNNKR
                     RVRFSDVAGADEEKQELIEIVDFLKDNKKFKEMGSRIPKGVLLVGPPGTGKTLLARAV
                     AGEAGAPFFSISGSDFVEMFVGVGASRVRDLFDNAKKNAPCIIFIDEIDAVGRQRGAG
                     VGGGHDEREQTLNQLLVEMDGFGENEGIIMIAATNRPDILDPALLRPGRFDRQIQVGR
                     PDVKGREAILHVHAKNKPLDETVDLKAISQRTPGFSGADLENLLNEASLIAVREGKKK
                     IDMRDIEEATDRVIAGPAKKSRVISKKERNIVAHHEAGHTIIGMVLDEAEVVHKVTIV
                     PRGQAGGYAMMLPKQDRFLMTEQELLDKICGLLGGRVSEDINFNEVSTGASNDFERAT
                     QIARSMVTQYGMSKKLGPLQFGHSNGQVFLGKDMQGEPNYSSQIAYEIDKEVQRIVKE
                     QYERCKQILLEHKEQLILIAETLLTEETLVAEQIQSLFYEGKLPEIDYDAAKVVKDED
                     SEFNDGKFGKSYEEIRKEQLEDGQRDESEDRKEEKDIAEDKKEADKSDEKDEPAHRQA
                     PNIEKPYDPNHPDNK"
     gene            31063..31944
                     /gene="hslO"
                     /locus_tag="RPH49_001105"
     CDS             31063..31944
                     /gene="hslO"
                     /locus_tag="RPH49_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDY5124282.1"
                     /translation="MTHDYIVKALAFDGEIRAYAALTTETVQEAQTRHYTWPTASAAM
                     GRTMTATAMMGAMLKGDQKLTVTVDGQGPIGRIIADANAKGEVRAYVDHPQTHFPLNE
                     QGKLDVRRAVGTNGSIMVVKDVGMKDYFSGASPIVSGELGEDFTYYYATSEQTPSSVG
                     LGVLVNPDNTIKAAGGFIIQVMPGAKDETISKLEKAISEMTPVSKLIEQGLTPEGLLN
                     EILGEDHVQILEKMPVQFECNCSHEKFLNAIKGLGEAEIQNMIKEDHGAEAVCHFCGN
                     KYKYTEEELNVLLESLA"
     gene            32123..33055
                     /gene="cysK"
                     /locus_tag="RPH49_001106"
     CDS             32123..33055
                     /gene="cysK"
                     /locus_tag="RPH49_001106"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDY5124283.1"
                     /translation="MAQKPVDNITQIIGDTPVVKLRNVVDDNAADVYVKLEYQNPGGS
                     VKDRIALAMIEKAEREGKIKPGDTIVEPTSGNTGIGLAFVCAAKGYKAVFTMPETMSQ
                     ERRNLLKAYGAELVLTPGSEAMKGAIKKAKELKEEHGYFEPQQFENPANPEVHELTTG
                     PELLQQFEGKTIDAFLAGVGTGGTLSGVGKVLKKEYPNIEIVAIEPEASPVLSGGEPG
                     PHKLQGLGAGFIPGTLNTEIYDSIIKVGNDTAMEMSRRVAKEEGILAGISSGAAIYAA
                     IQKAKELGKGKTVVTVLPSNGERYLSTPLYSFDD"
     gene            33271..34074
                     /gene="folP"
                     /locus_tag="RPH49_001107"
     CDS             33271..34074
                     /gene="folP"
                     /locus_tag="RPH49_001107"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDY5124284.1"
                     /translation="MTKTKIMGVLNVTPDSFSDGGKFNNVESAVTRVKAMMDEGADII
                     DVGGVSTRPGHEMVSLEEELNRVLPVVEAIVGFDVKISVDTFRSEVAEACLKLGVDII
                     NDQWAGLYDHHMFQIVAKYDAEIILMHNGNGNRDEPVVEEMLTSLLAQAHQAKIAGIP
                     SNKIWLDPGIGFAKTRNEEAEVMARLDELVATEYPVLLATSRKRFTKEMMGYDTTPVE
                     RDEVTAATTAYGIMKGVRAVRVHNVELNAKLAKGIDFLKENENARHNLS"
     gene            34052..34417
                     /gene="folB"
                     /locus_tag="RPH49_001108"
     CDS             34052..34417
                     /gene="folB"
                     /locus_tag="RPH49_001108"
                     /EC_number="4.1.2.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin aldolase"
                     /protein_id="HDY5124285.1"
                     /translation="MQDTIFLKGMRFYGYHGALSAENEIGQIFKVDVTLKVDLAEAGR
                     TDNVIDTVHYGEVFEEVKSIMEGKAVNLLEHLAERIANRINSQYNRVMETKVRITKEN
                     PPIPGHYDGVGIEIVRENK"
     gene            34414..34890
                     /gene="folK"
                     /locus_tag="RPH49_001109"
     CDS             34414..34890
                     /gene="folK"
                     /locus_tag="RPH49_001109"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDY5124286.1"
                     /translation="MIQAYLGLGSNIGDRESQLNDAIKILNEYDGINVSNISPIYETA
                     PVGYTEQPNFLNLCVEIQTTLTVLQLLECCLKTEECLHRVRKERWGPRTLDVDILLYG
                     EEMIDLPKLSVPHPRMNERAFVLIPLNDIAANVIEPRSKLKVKDLVFVDDSVKRYK"
     gene            35284..35376
                     /locus_tag="RPH49_001110"
     CDS             35284..35376
                     /locus_tag="RPH49_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124287.1"
                     /translation="MVNDKVLETSKEMYVEQKCLIFYKTLKENV"
     gene            35429..36916
                     /gene="lysS"
                     /locus_tag="RPH49_001111"
     CDS             35429..36916
                     /gene="lysS"
                     /locus_tag="RPH49_001111"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDY5124288.1"
                     /translation="MSEEMNDQMLVRRQKLQELYDLGIDPFGSKFDRSGLSSDLKEEW
                     DQYSKEELVEKEADSHVAIAGRLMTKRGKGKAGFAHVQDLAGQIQIYVRKDQVGDDEF
                     DLWKNADLGDIVGVEGVMFKTNTGELSVKAKKFTLLTKSLRPLPDKFHGLQDIEQRYR
                     QRYLDLITNEDSTRTFINRSKIIQEMRNYLNNKGFLEVETPMMHQIAGGAAARPFVTH
                     HNALDATLYMRIAIELHLKRLIVGGLEKVYEIGRVFRNEGVSTRHNPEFTMIELYEAY
                     ADYHDIMDLTESMVRHITNEVLGSAKVQYNGETIDLESAWTRLHIVDAVKEATGVDFY
                     EVKSDEEAKALAKEHGIEIKDTMKYGHILNEFFEQKVEETLIQPTFIYGHPTEISPLA
                     KKNPEDPRFTDRFELFIVGREHANAFTELNDPIDQKGRFEAQLVEKAQGNDEAHEMDE
                     DYIEALEYGMPPTGGLGIGIDRLVMLLTDSPSIRDVLLFPYMRQK"
     gene            37474..37588
                     /gene="rrf"
                     /locus_tag="RPH49_001112"
     rRNA            37474..37588
                     /gene="rrf"
                     /locus_tag="RPH49_001112"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            37601..37676
                     /locus_tag="RPH49_001113"
     tRNA            37601..37676
                     /locus_tag="RPH49_001113"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37634..37636,aa:Val,seq:tac)
     gene            37693..37768
                     /locus_tag="RPH49_001114"
     tRNA            37693..37768
                     /locus_tag="RPH49_001114"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37726..37728,aa:Thr,seq:tgt)
     gene            37775..37847
                     /locus_tag="RPH49_001115"
     tRNA            37775..37847
                     /locus_tag="RPH49_001115"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37808..37810,aa:Lys,seq:ttt)
     gene            37881..37955
                     /locus_tag="RPH49_001116"
     tRNA            37881..37955
                     /locus_tag="RPH49_001116"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37913..37915,aa:Gly,seq:gcc)
     gene            37963..38051
                     /locus_tag="RPH49_001117"
     tRNA            37963..38051
                     /locus_tag="RPH49_001117"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:37997..37999,aa:Leu,seq:taa)
     gene            38057..38133
                     /locus_tag="RPH49_001118"
     tRNA            38057..38133
                     /locus_tag="RPH49_001118"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38091..38093,aa:Arg,seq:acg)
     gene            38154..38227
                     /locus_tag="RPH49_001119"
     tRNA            38154..38227
                     /locus_tag="RPH49_001119"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38188..38190,aa:Pro,seq:tgg)
     gene            38251..38326
                     /locus_tag="RPH49_001120"
     tRNA            38251..38326
                     /locus_tag="RPH49_001120"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:38284..38286,aa:Ala,seq:tgc)
BASE COUNT        13753 a         5208 c         7778 g        11645 t
ORIGIN      
        1 tcaaagaagt gttactatat aattaatact tttgaaagta actaattcca aaacagtgta
       61 aataaaggaa gcgtatatca tgaagcaacc tattttaaat aaattagaaa gtttaaatca
      121 agaagaagcg atttctttgc atgttccggg tcataaaaat atgactatcg gtcatttatc
      181 tcaattatca atgacaatgg ataaaactga aatacctgga ttagatgatt tacatcatcc
      241 tgaagaagtc attttggaaa gtatgaagca ggtggagaaa cattcagatt atgatgctta
      301 tttcttagtg aatggcacca cttcaggaat attatctgtc atccagtctt tttcacagaa
      361 aaaaggcgat atcttaatgg caagaaatgt acataaatct gtgttacatg cgctcgatat
      421 tagccaacaa gaagggcatt ttattgaaac gcatcaaagt ccgttaacga atcattataa
      481 taaagttaat ttaagccgtt tgaataatga cggtcacaaa cttgctgtgt tgacttatcc
      541 taactattac ggtgaaacat ttaatgtaga agaggttatc aaatctttgc accaattaaa
      601 tattcctgta ctcattgacg aagcacacgg cgcgcacttt ggattgcaag gatttccaga
      661 ttctacatta aattatcaag ctgactatgt tgttcaatct tttcataaaa cgttaccagc
      721 tttaacgatg ggctcggtac tttatattca taaaaatgca ccttatagag aaactattat
      781 agaatatcta agctacttcc aaacatctag tccttcgtat ttgattatgg ctagtttaga
      841 gtcagctgcc gagttctata aaacatatga tagtaccgtg ttttttgata agagagcgca
      901 attaatcgaa tgtttggaga agaagggttt tgaaatgctt caagttgatg atccgttgaa
      961 gttgctgata aaatatgaag gttttacagg tcatgatatt caaaattggt ttatgaatgc
     1021 acatatctat ttagaattag cggacgacta tcaagcatta gcgatattgc cgttatggca
     1081 tcatgatgat acgtatttat ttgattcgct tttacgtaaa attgaagata tgattttacc
     1141 gaaaaaatca gtttctaaag ttaaacaaac acaactttta acaactgaag gtaactataa
     1201 accaaaacgc tttgaatatg ttacttggtg tgatttgaaa aaggcaaaag gtaaagttct
     1261 ggcgcgacat attgtcccgt atccgccagg gattcctatt attttcaaag gagaaacaat
     1321 aactgaaaat atgatagaat tggtaaatga atatctggaa actggaatga tagttgaagg
     1381 aattaaaaat aataaaattt tagttgagga tgaataaaat gtcagctttt ataacttttg
     1441 agggcccaga aggctctgga aaaacaactg taattaatga agtttaccat agattagtaa
     1501 aagattatga tgtcattatg actagagaac caggtggtgt tcctactggt gaagaaatac
     1561 gtaaaattgt attagaaggc aatgatatgg acattagaac tgaagcaatg ttatttgctg
     1621 catctagaag agaacatctt gtattaaagg tcataccagc tttaaaagaa ggtaaggttg
     1681 tgttgtgtga tcgctatatc gatagttcat tagcttatca aggttatgct agagggattg
     1741 gcgttgaaga agtaagagca ttaaacgaat ttgcaataaa tggattatat ccagacttga
     1801 cgatttattt aaatgttagt gctgaagtag gtcgcgaacg tattattaaa aattcaagag
     1861 atcaaaatag attagatcaa gaagatttaa agtttcacga aaaagtaatt gaaggttacc
     1921 aagaaatcat tcataatgaa tcacaacggt tcaaaagcgt taatgcagat caacctcttg
     1981 aaaatgttgt tgaagacacg tatcaaacta tcatcaaata tttagaaaag atatgatata
     2041 attgttagaa gaggtgttat aaaatgaaaa tgattatagc gatcgtacaa gatcaagata
     2101 gtcaggaact tgcagatcaa cttgttaaaa ataactttag agcaacaaaa ttggcaacaa
     2161 caggtgggtt tttaagagcg ggtaatacaa cattcttatg tggtgtcaat gatgaccgtg
     2221 tagatgaaat attgtctgtg attaatcaaa cgtgtggtaa tagagaacag ttggtttcac
     2281 ctattacacc tatgggaggc agtgcggatt cgtacattcc atatccagtt gaagttgaag
     2341 ttggcggtgc tactgtattt gttatgccag ttgatgcatt ccatcaattt taattctata
     2401 atacaatcat caattagaga tacttaaaat agtgtattaa taagttatta acaattttgg
     2461 gttgcttgac tgcgactagt tcagatgcca atagatttga tttttgtggt tctaaaaata
     2521 atcacaaatc atggtcgcta ttgttgcagt aattagttgc tctttggcaa cctttttata
     2581 taaaagcaaa agggagtttg taatgaatgg atgaacagca acaattgacg aatgcatatc
     2641 attcaaataa attatcgcat gcctatttat ttgaaggtga tgatgcacaa acgatgaaac
     2701 aagttgcgat taattttgca aagcttattt tatgtcaaac agatagtcaa tgtgaaacaa
     2761 aggttagtac atataatcat ccagacttta tgtatatatc aacaactgag aatgcaatta
     2821 agaaagaaca agttgaacaa cttgtgcgtc atatgaatca acttcctata gaaagcacaa
     2881 ataaagtgta catcattgaa gactttgaaa agttaactgt tcaaggggaa aacagtatct
     2941 tgaaatttct tgaagaacca ccggacaata cgattgctat tttattgtct acaaaacctg
     3001 agcaaatttt agacacaatc cattcaaggt gtcagcatgt atatttcaag cctattgata
     3061 aagaaaagtt tataaataga ttagttgaac aaaacatgtc taagccagta gctgaaatga
     3121 ttagtactta tactacgcaa atagataatg caatggcttt aaatgaagaa tttgatttat
     3181 tagcattaag gaaatcagtt atacgttggt gtgaattgtt gcttactaat aagccaatgg
     3241 cacttatagg tattattgat ttattgaaac aggctaaaaa taaaaaactg caatctttaa
     3301 ctattgcagc tgtgaatggt ttcttcgaag atatcataca tacaaaggta aatgtagagg
     3361 ataaacaaat atatagtgat ttaaaaaatg atattgatca atatgcgcaa aagttgtcgt
     3421 ttaatcaatt aattttgatg tttgatcaac tgacggaagc acataagaaa ttgaatcaaa
     3481 atgtaaatcc aacgcttgta tttgaacaaa tcgtaattaa gggtgtgagt tagatgccaa
     3541 atgtaatagg tgttcagttt caaaaagcgg gaaaattaga atattataca cctaatgata
     3601 tacaagtaga tatagatgac tgggtagttg tcgaatctaa aagaggcata gagataggta
     3661 ttgttaaaaa tccattaatg gatattgctg aagaggatgt tgtgttacct cttaaaaata
     3721 ttattcgcgt tgctgatgac aaagatattg ataaatttaa ttgtaatgaa cgagatgctg
     3781 aaaatgcatt aatactatgt aaagacattg taagagaaca aggtttggac atgcgtttag
     3841 tcaattgcga atatacatta gataaatcga aagttatttt taattttacg gcggatgatc
     3901 gtattgattt tagaaaatta gtaaaaatat tagcgcaaca tttaaaaaca cgtatcgagt
     3961 tgagacaaat tggtgtaagg gatgaagcca aattgcttgg cggtatcgga ccttgtggta
     4021 ggtcgttatg ttgttctaca tttttagggg attttgaacc agtatcgatt aagatggcta
     4081 aggatcaaaa tttatcatta aatccaacta aaatttctgg tgcatgtggt cgtttgatgt
     4141 gttgtttaaa atatgaaaat gactattatg aggaagtacg tgcacaatta cctgatattg
     4201 gtgaagcaat tgaaacgcct gatggtaacg ggaaagtagt tgctttaaat atattagaca
     4261 tttctatgca ggtgaagctt gagggacatg aacagccact tgaatataaa ttagaagaaa
     4321 tagaaactat gcattaagga ggcattatta catttggatc gcaatgaaat atttgaaaaa
     4381 ataatgcgtt tagaaatgaa tgtcaatcaa ctttcaaaag aaacttcaga attaaaggca
     4441 cttgcagttg aattagtaga agaaaatgta gcgcttcaac ttgaaaatga taatttgaaa
     4501 aaggtgttgg gcaatgatga accaactact attgatactg cgaattcaaa accagcaaaa
     4561 gctgtgaaaa agccattacc aagtaaagat aatttggcta tattgtatgg agaaggattt
     4621 catatttgta aaggcgaatt atttggaaaa catcgacatg gtgaagattg tctgttctgt
     4681 ttagaagttt taagtgatta atcaagcaca ctcaaatagt gttataatta taaatgaata
     4741 tggtttggat aagtctgaga caatgcatgt ttcaggcttt aattgtgtat aaagttttgg
     4801 tgattgcata agagatagcg gtactaaatg ttattattaa gtgtgcacgc agtatcatta
     4861 gttataaaat gtagctgtta aaagtcaaaa atacatcgaa tgtagatagg catataatat
     4921 aaaaagagat ttcaattact caatagaaaa aggttgtctt cataggagtt aaaaatgtta
     4981 aaagagaatg aacgatttga tcaactaatc aaagaagatt ttagtattat tcaaaatgat
     5041 gatgtttttt cgttttcaac ggatgctttg ttgttagggc attttacaaa acctagaaca
     5101 aaagatattg tgttggactt atgttcaggc aatggggtga taccgttgtt attgtttgcg
     5161 aaacatccac gacatataga aggtgttgag attcaaaaaa cacttgtcga tatggcgcga
     5221 cgcacatttc aattcaatga tgttgatgaa tatataacaa tgcatcacat ggatttgaaa
     5281 aacgttacta aagtatttaa accttcacaa tatactttag taacgtgtaa tccaccttat
     5341 tttaaagaga atcagcaaca ccaacatcaa aaagaagcac ataagatagc gagacatgag
     5401 attatgtgta cacttgaaga ttgcatgatt gcagcccgtc atttattaaa agaaggtggc
     5461 aggctaaaca tggtacatcg tgcagagaga ctaatggatg tcttgtttga aatgagaaaa
     5521 gtgaatattg aacctaagaa agtcgttttt atatatagta aagtagggaa atcagcacaa
     5581 acgatagtag tagaaggtcg aaaaggtgga aatcaaggtt tagaaatcat gcccccattt
     5641 tatatttata atgaagatgg taattatagc gaagaaatga aggaagtata ttatggatag
     5701 tcattttgta tatattgtaa aatgtagtga tggaagttta tatacaggat acgctaaaga
     5761 cgttaatgca cgtgttgaaa aacataaccg aggtcaagga gccaaatata cgaaagtaag
     5821 acgtccggtg catttagttt atcaagaaat gtatgagaca aagtctgaag cattgaagcg
     5881 tgaatatgaa attaaaactt ataccagaca aaagaaattg cgattaatta aggagcgata
     5941 gtatggctgt attatattta gtgggcacac caattggtaa tttagcagat attacttata
     6001 gagcagttga tgtattgaaa cgtgttgata tgattgcttg tgaagacact agagtaacta
     6061 gtaagctgtg taatcattat gatattccaa ctccattaaa gtcatatcac gaacataaca
     6121 aggataagca gactgctttt atcattgaac agttagaatt aggtcttgac gttgcgctcg
     6181 tatctgatgc tggattgccc ttaattagtg atcctggata cgaattagta gtggcagcca
     6241 gagaagctaa tattaaagta gagactgtgc ctggacctaa tgctgggctg acggctttga
     6301 tggctagtgg attaccttca tatgtatata catttttagg atttttgcca cgaaaagaga
     6361 aagaaaaaag tgctgtatta gagcaacgta tgcatgaaaa tagcacatta attatatacg
     6421 aatcaccgca tcgtgtgaca gatacattaa aaacaattgc aaagatagat gcaacacgac
     6481 aagtatcact agggcgtgaa ttaactaaga agttcgaaca aattgtaact gatgatgtaa
     6541 cacaattaca agcattgatt cagcaaggcg atgtaccatt gaaaggcgaa ttcgttatct
     6601 taattgaagg tgctaaagcg aacaatgaga tatcgtggtt tgatgattta tctatcaatg
     6661 agcatgttga tcattatatt caaacttcac agatgaaacc aaaacaagct attaaaaaag
     6721 ttgctgaaga acgacaactt aaaacgaatg aagtatataa tatttatcat caaataagtt
     6781 aatcacttta tcgattatat gaaatttcaa acgattttat aaacgcaagc tgtaatttta
     6841 aatggtaagt tatcattttg cattgatact gataaaatga tgttgactat gataaaaaaa
     6901 tgatgacatc gacgtttttt aatgtaaaat aaatacattg aaagtaataa ataccttaac
     6961 attgaataag atgaaaatga gatgacgaga taaatgttcg cgtccgttga aatgcataga
     7021 aatcttagat attatttgaa gtgagacatt acgaggagga acagttatgg ctaaagaaac
     7081 attttatata acaaccccaa tatactatcc tagtgggaat ttacatatag gacatgcata
     7141 ttctacagtg gctggagatg ttattgcaag atataagaga atgcaaggat atgatgttcg
     7201 ttatttgact ggaacggatg aacacggtca aaaaattcaa gaaaaagctc aaaaagctgg
     7261 taagacagaa attgaatatt tggatgagat gattgctgga attaaacaat tgtgggctaa
     7321 gcttgaaatt tcaaatgatg attttatcag aacaactgaa gaacgtcata aacatgtcgt
     7381 tgagcaagtg tttgaacgtt tattaaagca aggtgatatc tatttaggtg aatatgaagg
     7441 ttggtattct gttccggatg aaacatacta tacagagtca caattagtag acccacaata
     7501 cgaaaacggt aaaattattg gtggcaaaag tccagattct ggacacgaag ttgaactagt
     7561 taaagaagaa agttatttct ttaatattag taaatataca gaccgtctat tagaattcta
     7621 tgaccaaaac ccagatttta tacaaccacc atcaagaaaa aatgaaatga ttaacaactt
     7681 cattaaacca ggacttgctg atttagctgt ttctcgtaca tcatttaact ggggtgtcca
     7741 tgttccgtct aatccaaaac atgttgttta tgtttggatt gatgcgttag ttaactatat
     7801 ttcagcatta ggctatttat cagatgatga gtcactattt aacaaatact ggccagcaga
     7861 tattcattta atggctaagg aaattgtgcg attccactca attatttggc ctattttatt
     7921 gatggcatta gacttaccgt tacctaaaaa agtctttgca catggttgga ttttgatgaa
     7981 agatggaaaa atgagtaaat ctaaaggtaa tgtcgtagac cctaatattt taattgatcg
     8041 ctatggttta gatgctacac gttattatct aatgcgtgaa ttaccatttg gttcagatgg
     8101 cgtatttaca cctgaagcat ttgttgagcg tacaaatttc gatctagcaa atgacttagg
     8161 taacttagta aaccgtacga tttctatggt taataagtac tttgatggcg aattaccagc
     8221 gtatcaaggt ccacttcatg aattagatga agaaatggaa gctatggctt tagaaacagt
     8281 gaaaagctac actgaaagca tggaaagttt gcaattttct gtggcattat ctacggtatg
     8341 gaagtttatt agtagaacga ataagtatat tgacgaaaca acgccttggg tattagctaa
     8401 ggacgatagc caaaaagata tgttaggcaa tgtaatggct cacttagttg aaaatattcg
     8461 ttatgcagct gtattattac gtccattctt aacacatgcg ccgaaagaga tttttgaaca
     8521 attgaacata aacaatcctc aatttatgga atttagtagt ttagagcaat atggtgtgct
     8581 tactgagtca attatggtta ctgggcaacc taaacctatt ttcccaagat tggatagcga
     8641 agcggaaatt gcatatatca aagaatcaat gcaaccgcct gctactgaag aggaaaaaga
     8701 agagattcct agcaaacctc aaattgatat taaagacttt gataaagttg aaattaaggc
     8761 agcaacgatt attgatgctg aacatgttaa gaagtcagat aagcttttaa aaattcaagt
     8821 agacttagat tctgaacaaa gacaaattgt atcaggaatt gccaaattct atacaccaga
     8881 tgatattatt ggtaaaaaag tagcagttgt tactaacctg aaaccagcta aattaatggg
     8941 acaaaaatct gaaggtatga tattatctgc tgaaaaagat ggtgtattaa ccttagtaag
     9001 tttaccaagt gcaattccaa atggtgcagt gattaaataa ctgtattttt aaaaattagg
     9061 agagataatt atgttaatcg atacacatgt ccatttaaat gatgagcaat acgatgatga
     9121 tttgagtgaa gtgattacac gtgctagaga agcaggtgtt gatcgtatgt ttgtagttgg
     9181 ttttaacaaa tcgacaattg aacgcgcgat gaaattaatc gatgagtatg attttttata
     9241 tggcattatc ggttggcatc cagttgacgc aattgatttt acagaagaac acttggaatg
     9301 gattgaatct ttagctcagc atccaaaagt gattggtatt ggtgaaatgg gattagatta
     9361 tcactgggat aaatctcctg cagatgttca aaaggaagtt tttagaaagc aaattgcttt
     9421 agctaagcgt ttgaagttac caattatcat tcataaccgt gaagcaactc aagactgtat
     9481 cgatatctta ttggaggagc atgctgaaga ggtaggcggg attatgcata gctttagtgg
     9541 ttctccagaa attgcagata ttgtaactaa taagctgaat ttttatattt cattaggagg
     9601 acctgtgaca tttaaaaatg ctaaacagcc taaagaagtt gctaagcatg tgtcaatgga
     9661 gcgtttgcta gttgaaaccg atgcaccgta tctttcgcca catccgtata gagggaagcg
     9721 aaatgaaccg gcgagagtaa ctttagtagc tgaacaaatt gctgaattaa aaggcttatc
     9781 ttatgaagaa gtgtgcgaac aaacaactaa aaatgcagag aaattgttta atttaaattc
     9841 ataaagttaa aagtgagaaa gatcaccgcc ataaatgtaa acgatgctat attcgtttaa
     9901 tatgctatgg ttctttctca cttttttaaa ttaaaatatc gtgcatgtgg aatacgtgcg
     9961 atagagatgg ttagagcttt gaaattaaga attgtaggaa ggcgttttaa atgaaaatca
    10021 atgagtttat agttgtagaa ggacgagatg atactgagcg tgttaaacga gctgttgaat
    10081 gtgatacgat tgaaacgaat ggtagtgcca tcaacgaaca aactttagaa gtaattagaa
    10141 atgctcaaca aagtcgaggc gttattgtat taacagatcc agatttccca ggagataaaa
    10201 ttagaagtac aattactgaa catgtcaaag gtgttaaaca tgcgtatatt gatagagaaa
    10261 aagctaaaaa taaaaaaggg aaaattggtg ttgaacatgc cgacttaatt gatattaaag
    10321 aagcgttaat gcatgttagt tcaccctttg atgaagctta tgaatcaatt gataaatctg
    10381 tgctaataga gttggggtta atcgttggga aagatgcaag gcgccgtaga gaaattttaa
    10441 gtagaaaatt gcgaatcggc cattccaatg gtaagcagtt attgaaaaag ttaaatgcat
    10501 ttggttatac cgaagcggat gtaaggcaag ctttagaaga tgaatgagga agtgaaaata
    10561 ttggataata aagatattgc aacaccatca agaacgcgag cgttgttaga taaatatggc
    10621 tttaatttta aaaaaagttt aggacagaac tttttgatag atgtgaatat cattaataat
    10681 atcattgatg caagtgatat tgatgcacaa actggggtga ttgaaattgg tccaggtatg
    10741 gggtcattga cagaacaatt ggccagacat gctaaaaggg tattggcatt tgaaattgat
    10801 caacgtttaa tacctgtatt aaatgatact ctatcacctt atgataatgt gacggtgatt
    10861 aatgaagata ttttaaaagc gaatattaaa gaagctgttg aaaatcattt acaagattgt
    10921 gaaaaaataa tggttgttgc aaacctgccg tactatatta cgacgccaat tttattaaat
    10981 ttaatgcaac aagatatacc aattgatggc tacgtggtga tgatgcaaaa agaagtgggc
    11041 gaacgcttaa atgctgaagt aggttcaaaa gcatatggtt cgttatcaat tgtcgtacaa
    11101 tactatacag agactagtaa agtattaacg gtacctaaat ctgtatttat gccaccacct
    11161 aatgttgatt caatagttgt aaaactgatg cagagaactg aaccgttagt aacagtagat
    11221 aacgaggaag cattctttaa gttagcaaaa gcagcatttg cacaaagaag aaagacaatt
    11281 aacaataact atcaaaatta ttttaaagat ggtaaacaac acaaagaagt gattttacaa
    11341 tggttagaac aagcggggat tgatccaaga cgtcgcggtg aaacgctatc tattcaagat
    11401 tttgctaaat tgtatgaaga aaagaaaaaa ttccctcaat tagaaaatta aatgattgac
    11461 aaagcaaagc actattgtta aaatttaaat tttgtttgac gaaaacgctg caaatatggt
    11521 attatgtaac ttgtagcgag gtggagcaat atgccaaaat caattttgga catcaaaaat
    11581 tctattgatt gtcatgtagg aaatcgtatt gtactgaaag ccaatggagg ccgtaagaaa
    11641 acaataaaac gttctggaat tttaaaagaa acatatccgt cagttttcat tgttgagtta
    11701 gatcaagaca aacacaactt tgagagagta tcttatacat acactgatgt gttaactgaa
    11761 aatgttcaag tttcatttga agaggataat catcacgaat caattgcaca ctaaataaga
    11821 catatagaga tgttagacgt ttcttagtat aagaagtaaa tattatgata attatttgag
    11881 tgttgggcat tatgttcaat actcttttta tttacaaaat gtttaacact gatgtttcgc
    11941 ttatagattt tcagtaaatg gatacttgta tttataaaca caaatacaag taaatactaa
    12001 gtaattagat ggagaaaatt acttttttat taaaaaaaca ctaaaaaaca aattaaaatg
    12061 tcaaatatta attctcttta tgttaaaatc atcatattaa gataacgaaa agagggcgga
    12121 aaatgatata tgaaacggca ccagccaaaa ttaattttac gctcgataca ctttttaaaa
    12181 gaaatgatgg ctatcatgag attgaaatga taatgacaac agttgattta aatgatcgtt
    12241 taacttttca taaaagaaaa gatcgaaaga tagttgttga gattgaacat aattatgtgc
    12301 cttctaatca taaaaatctc gcatatcgtg cagcgcaact atttattgag caatatcaac
    12361 taaagcaagg tgtaacaatt tctatcgata aagaaatacc tgtttctgct ggcttagctg
    12421 gaggttcggc tgatgcagca gcaactttaa gaggattgaa tcgacttttt gatatagggg
    12481 cgagtttgga agaattggct ctactaggca gtaaaatcgg gacagatatt ccgttttgta
    12541 tttataataa aactgcacta tgtactggaa gaggagagaa aatcgagttt ttaaataaac
    12601 caccttcagc ttgggtgatt cttgctaaac caaacttagg catatcatca ccagatatat
    12661 ttaagttgat taatttagat aagcgttacg acgtacatac gaaaatgtgt tatgaggcct
    12721 tagaaaatcg agattatcaa caattatgtc aaagtttgtc taatcgatta gagccaattt
    12781 ctgtttcaaa acacccacaa atcgataaat taaaaaataa tatgttgaaa agtggtgcag
    12841 atggtgcgtt aatgagtgga agcggaccta ctgtgtatgg gctagcacga aaagaaagcc
    12901 aagcaaaaaa tatttataat gcagttaacg gttgttgtaa tgaagtgtac ttagttagac
    12961 tattaggata gaagggttga aaagatgaga tataaacgaa gcgagagaat tgtttttatg
    13021 acgcaatatt tgatgaacca tccgaataaa ttgattccat taactttttt tgtgaaaaaa
    13081 tttaaacagg cgaagtcttc aataagtgaa gatgtccaaa ttataaaaaa tacattccaa
    13141 aaagaaaagt taggtacagt aattactact gctggcgcaa gtggtggtgt tacgtataaa
    13201 ccaatgatga gtaaagaaga ggcgactgaa gttgttaatg aggtcattac tctattagaa
    13261 gagaaagaac gtttgttacc tggcggatat ttatttttat cagatttggt aggtaatcca
    13321 tcgctactaa acaaagttgg taagttaatt gccagtattt acatggaaga aaaattagat
    13381 gctgttgtta ccattgcgac aaaaggtatt tcattggcaa atgcggttgc taatatttta
    13441 aatttaccag tagtagtgat tagaaaagac aacaaggtga ctgaaggttc tacagtttca
    13501 attaattacg tttcaggatc ttcaagaaaa atagaaacaa tggtactttc gaagagaact
    13561 ttagcagaaa attcaaatgt tttagttgtc gatgatttta tgagggctgg tggctctatt
    13621 aatggtgtta tgaatttaat gaatgagttt aaagcccatg taaaaggggt atcagtactt
    13681 gtagaatcaa aagaagttaa acaaagattg attgaagatt atacttcctt agtgaaatta
    13741 tctgatgtag atgaatataa tcaagagttt aacgtagaac ctggcaacag tttatctaag
    13801 ttttcataaa aggagtttta gtattatgaa aatcattaac acaacaagat taccggaagc
    13861 acttggacca tattcgcatg caacagttgt gaatggtatg gtttatactt ctggtcagat
    13921 tccattgaat attgatggac atatcgtaag cgctgatgtt caagcacaga caaaacaagt
    13981 tttagaaaat ttaaaggttg ttttggaaga agcaggatct gatttggatt ctgttgcgaa
    14041 agcgaccatt ttcattaaag atatgaatga tttccaaaaa ataaatgaag tgtatggtca
    14101 atattttaat gaacacaagc cagcgcgtag ttgtgtagag gttgcgcgtt tgccaaaaga
    14161 tgtgaaagta gaaattgaat tagtaagtaa aattaaggaa ttataatttt cgattaatat
    14221 gtttaatcaa gcttctaaat aaaacagaga tatatatact ataggggggc tcactacatg
    14281 aaagtgacag atgtaagact tagaaaaata caaacagatg gacgaatgaa agcactcgtt
    14341 tccattacat tagatgaagc tttcgtaatt catgatttac gtgtaattga aggaaactct
    14401 ggcttgttcg ttgcaatgcc aagtaaacgt acaccagatg gtgaattccg cgacatcgcg
    14461 catcctatta attcagatat gagacaagaa attcaagatg cagtgatgaa agtatatgat
    14521 gaaacagatg aagtagtacc agataaaaac gctacatcag aagattcaga agaagcttaa
    14581 tcaattttat atttagcgat gtaatacatt tgcaataagt tgatttgata ctgtcgataa
    14641 agcataaagc tttgtcggca gtttttttag tttgtattaa tgttttttta tttttaatga
    14701 aaggctaata aatatatacg ttaacagatt atgatgatat gaaaattatt gattcattgc
    14761 tgataaaaat tgcgtttgaa tgatgctcgt atttttgaag taagaaaaaa gttgttttta
    14821 aaattacaac gaattaaaaa caatgccttt tatatgttga aagagtattg cagattaaat
    14881 tataataatg acgaagtgta aaatttaatg ggggttaatg ttcatgcgaa gacacgcgat
    14941 aattttggca gcaggtaaag gcacaagaat gaaatctaaa aagtataaag tgctacacga
    15001 ggttgctggg aaacctatgg tcgaacatgt attggaaagt gtgaaaggct ctggtgtcga
    15061 tcaagttgta accatcgtag gacatggtgc tgaaagtgta aaaggacatt taggcgagcg
    15121 ttctttatac agttttcaag aggaacaact cggtactgcg catgcagtgc gaatggcgaa
    15181 atcacactta gaagacaagg aaggtacgac gatcgttgta tgtggtgaca caccgctcat
    15241 cacaaaggaa acattagaaa cattgattgc gcatcacgag gatgctaatg ctcaagcaac
    15301 tgtattatct gcatcgattc aacaaccata tggatacgga agaatcgttc gaaatgcgtc
    15361 aggtcgttta gaacgcatag ttgaagagaa agatgcaacg caagctgaaa aggatattaa
    15421 tgaaatcagt tcaggtattt ttgcgtttaa taataaaacg ttgtttgaaa aattaacaca
    15481 agtgaaaaat gataatgcgc aaggtgaata ttacctccct gatgtattgt cgttaatttt
    15541 aaatgatggc ggcatcgtag aagtctatcg taccaatgat gttgaagaaa tcatgggtgt
    15601 aaatgatcgt gtaatgctta gtcaggctga gaaggcgatg caacgtcgta cgaatcatta
    15661 tcacatgcta aatggtgtga caatcatcga tcctgacagc acttatattg gtccagacgt
    15721 tacaattggt agtgatacag tcattgaacc aggcgtacga attaacggtc gtacagaaat
    15781 tggcgaagat gttgttattg gtcagtactc tgaaattaac aatagtacga ttgaaaatgg
    15841 tgcatgtatt caacagtctg ttgttaatga tgctagcgta ggagctaata ctaaggtcgg
    15901 accgtttgcg caattgagac caggcgcgca attaggtgca gatgttaagg ttggaaattt
    15961 tgtagaaatt aaaaaagcag atcttaaaga tggtgccaag gtttcacatt taagttatat
    16021 tggcgatgct gtaattggcg aacgtactaa tattggttgc ggaacgatta cagttaacta
    16081 tgatggtgaa aataaattta aaactatcgt cggcaaagat tcatttgtag gttgcaatgt
    16141 taatttagta gcacctgtaa caattggtga tgatgtattg gtggcagctg gttccacaat
    16201 cacagatgac gtaccaaatg acagtttagc tgtggcaaga gcaagacaaa caacaaaaga
    16261 aggatatagg aaataatcat ttacgtattt aaaatggcta ggataaaagg ataatcctat
    16321 gtaatattaa tgtaatcttt atgatttaat gattcgcata gtaatggagt tacattttat
    16381 atataatagt aattgcgtaa gtaaataatt ggaggactat aaatgttaaa taatgaatat
    16441 aagaattcgt cattaaagat tttttcattg aaaggaaacg aagcattagc gcaagaagtt
    16501 gctgaccaag taggaattga actaggtaaa tgttcagtta aacgttttag tgatggagaa
    16561 attcaaatta atatcgaaga gagtattcgt ggttgtgacg tatttattat tcaaccaaca
    16621 tcatatcctg tgaatctaca tctaatggaa ttattaatta tgattgatgc ttgtaaacgt
    16681 gcttctgcag caacaatcaa tattgtagtg ccatattatg gatatgcaag acaagataga
    16741 aaagcccgta gccgtgagcc aatcacagct aaattagttg caaacttaat agaaacagct
    16801 ggcgcaactc gtatgattgc gttagactta catgcaccac aaattcaagg attctttgat
    16861 attccaattg accacttaat gggtgtgcca attcttgcta aacatttcaa agatgatccg
    16921 aatattaacc cagaagaatg tgtcgttgtt tcaccagacc atggcggtgt tacacgtgca
    16981 cgtaaattag ctgacatttt aaaaactcca attgcaatta tagataaacg tcgtcctaga
    17041 ccaaatgttg ctgaagtgat gaacattgtt ggtgagattg aaggacgtac ggcaattatt
    17101 attgacgata ttattgatac agcaggtaca atcactttag ctgcacaagc attaaaagat
    17161 aaaggtgcta aagaagtata tgcttgttgt acacaccctg ttttatcagg accggctaaa
    17221 gaacgtatcg aaaattctgc tataaaagaa ttaatcgtaa caaactcaat tcatttagat
    17281 gaagaccgca aaccatctaa cactaaagaa ttatctgttg ctggtttaat cgcacaagct
    17341 atcattcgtg tatacgaaag agaatcagtt agcgtattat ttgactaata tttaaaaggc
    17401 gtttgacgaa catatcccaa acgtgtataa tagtttcgtt cgtgattata cgaataaata
    17461 aacacttgca agcaacgatg atgttgatgg gtaagtgagg tgctcgtttt gagcaaaaat
    17521 gaaaggtgga aatgagaatg gcttcattaa agtcaatcat ccgtcaaggt aaacaaacac
    17581 gttcagatct taaacaatta agaaaatctg gtaaagtacc agcagtagta tacggttacg
    17641 gtactaaaaa cgtgtcagtt aaagttgatg aagtagaatt catcaaagtt atccgtgaag
    17701 taggtcgtaa cggtgttatc gaattaggcg ttggttctaa aactatcaaa gttatggttg
    17761 cagactacca attcgatcca cttaaaaacc aaattactca cattgacttc ttagcaatca
    17821 atatgagtga agaacgtact gttgaagtac cagttcaatt agttggtgaa gcagtaggcg
    17881 ctaaagaagg cggcgtagtt gaacaaccat tattcaactt agaagtaact gctactccag
    17941 acaatattcc agaagcaatc gaagtagaca ttactgaatt aaacattaac gacagcttaa
    18001 ctgttgctga tgttaaagta actggcgact tcaaaatcga aaacgattca gctgaatcag
    18061 tagtaacagt agttgctcca actgaagaac caactgaaga agaaatcgaa gctatggaag
    18121 gcgaacaaca aactgaagaa ccagaagttg ttggcgaaag caaagaagac gaagaaaaaa
    18181 ctgaagagta attttaatct gttacattaa agtttttata ctttgtttaa caagcactgt
    18241 gcttatttta atataagcat ggtgcttttt gtgttattat aaagcttaat taaactttat
    18301 tgctttgtac taaagtttaa ttaattttag tgagtaaaag acattaaact caacaatgat
    18361 acatcataaa aatttttatg tactcgattt taaaatacat acttactaag ctaaagaata
    18421 atgataattg atggcaatgg cggaaaatgg atgttgtcat tataataata aatgaaacaa
    18481 ttatgttgga ggtaaacacg catgaaatgt attgtaggtc taggtaatat aggtaaacgt
    18541 tttgaactta caagacataa tatcggcttt gaagtcgttg attatatttt agagaaaaat
    18601 aatttttcat tagataaaca aaagtttaaa ggtgcatata caattgaacg aatgaacggc
    18661 gataaagtgt tatttatcga accaatgaca atgatgaatt tgtcaggtga agcagttgca
    18721 ccgattatgg attattacaa tgttaatcca gaagatttaa ttgtcttata tgatgattta
    18781 gatttagaac aaggacaagt tcgcttaaga caaaaaggaa gtgcgggcgg tcacaatggt
    18841 atgaaatcaa ttattaaaat gcttggtaca gaccaattta aacgtattcg tattggtgtg
    18901 ggaaggccaa cgaatggtat gacggtacct gattatgttt tacaacgctt ttcaaatgat
    18961 gaaatggtaa cgatggaaaa agttatcgaa cacgcagcac gcgcaattga aaagtttgtt
    19021 gaaacatcac gatttgacca tgttatgaat gaatttaatg gtgaagtgaa ataatgacaa
    19081 tattgacaac gcttataaaa gaagataatc attttcaaga ccttaatcag gtatttggac
    19141 aagcaaacac actagtaact ggtctttccc cgtcagctaa agtgacgatg attgctgaaa
    19201 aatatgcaca aagtaatcaa cagttattat taattaccaa taatttatac caagcagata
    19261 aattagaaac agatttactt caatttatag atgctgaaga attgtataag tatcctgtgc
    19321 aagatattat gaccgaagag ttttcaacac aaagccctca actgatgagt gaacgtatta
    19381 gaactttaac tgcgttagct caaggtaaga aagggttatt tatcgttcct ttaaatggtt
    19441 tgaaaaagtg gttaactcct gttgaaatgt ggcaaaatca ccaaatgaca ttgcgtgttg
    19501 gtgaggatat cgatgtggac caatttctta acaaattagt taatatgggg tacaaacggg
    19561 aatccgtggt atcccatatt ggtgaattct cattgcgagg aggtattatc gatatctttc
    19621 cgctaattgg ggaaccaatc agaattgagc tatttgatac cgaaattgat tctattcggg
    19681 attttgatgt tgaaacgcag cgttccaaag ataatgttga agaagtcgat atcacaactg
    19741 caagtgatta tatcattact gaagaagtga tcagccatct taaagaagag ttaaaaactg
    19801 catatgaaaa tacaagaccc aaaatagata aatcagtgcg caatgatttg aaagaaacgt
    19861 atgaaagctt taaattattc gaaagtacat actttgatca tcaaatacta cgtcgtttag
    19921 tagcgtttat gtatgaaaca ccttcgacaa ttattgagta tttccaaaaa gatgcaatca
    19981 ttgcagttga tgaatttaat cgtattaaag aaactgaaga aagtttaaca gtagagtctg
    20041 attcgtttat tagcaatatt attgaaagtg gtaatggatt tataggacaa agttttataa
    20101 aatatgatga ttttgaaaca ttgattgaag gctatcctgt cacttatttt tcattattcg
    20161 ctacaacaat gccgataaaa ctaaatcata ttattaaatt ttcatgtaaa cctgtccaac
    20221 aattttatgg gcaatatgac attatgcgtt ctgaatttca acgatatgtc aatcaaaatt
    20281 atcatattgt ggttttggtc gaaactgaaa ctaaagttga acgtatgcaa gcgatgttaa
    20341 gtgaaatgca tattccatca ataacaaaat tgcatcgctc aatgtcatcg gggcaagcag
    20401 tgattattga aggcagttta tctgaaggat ttgaactacc tgatatggga ttagttgtca
    20461 ttactgagcg tgagcttttt aaatcaaaac agaaaaagca acgaaaacgt acgaaagcta
    20521 tctcaaatgc tgaaaaaatt aagtcttacc aagatttaaa tgtgggagat tatattgttc
    20581 atgtgcatca tggtgttggt agatatttag gtgttgagac gctcgaagtg gggcaaacgc
    20641 atcgggatta tattaaattg caatataaag gtacggatca actatttgtt ccagtagatc
    20701 aaatggatca agttcaaaaa tatgtagctt cggaagataa gacgccaaaa ttaaataaac
    20761 tcggtggcag tgaatggaaa aaaacaaaag ctaaagttca acaaagtgtt gaagatattg
    20821 ctgaagagtt gattgattta tataaagaaa gagaaatggc agaaggttat caatatgggg
    20881 aagacacagc tgagcaaaca acatttgaat tagattttcc atatgaactt acgcctgacc
    20941 aagctaaatc tatcgatgaa attaaagatg acatgcaaaa atcgcgtcca atggatcgct
    21001 tgctatgtgg tgatgttggt tatggtaaaa ctgaagttgc agtgagagca gcattcaaag
    21061 ctgtaatgga aggaaagcaa gttgcatttt tagttcctac aactatttta gctcagcaac
    21121 attatgagac gttaattgag cgtatgcaag attttcctgt tgaaattcaa ttaatgagtc
    21181 gttttagaac gccaaaagag ataaaacaaa ctaaggaagg acttaaaact gggtttgttg
    21241 acatagttgt tggtacacac aaattactta gtaaagatat acagtataaa gatttagggc
    21301 tgttgattgt agatgaagaa caacgatttg gtgtacgcca taaagagcgt attaaaacat
    21361 taaaacataa tgtagatgta ctaacattga ctgcaacccc aatacctaga acattgcata
    21421 tgagtatgct aggtgtgcgc gatttgtcag tgattgaaac gccgccagaa aatcgtttcc
    21481 cagttcaaac atatgtatta gaacagaaca tgagttttat caaagaagct ttagaaagag
    21541 aactatcccg tgatggccaa gtgttttatc tttataataa agtgcaatcc atttatgaaa
    21601 aacgagaaca actccagatg ttaatgccag atgctaacat tgcagttgct catggacaaa
    21661 tgacagagcg cgatttagaa gaaacgatgt taagttttat caataatgaa tatgatattt
    21721 tagtaacgac gacgattatt gaaacaggtg tcgatgtccc aaatgcaaat actttgatca
    21781 ttgaagatgc agatcgcttt ggattgagtc agttgtatca attaagaggt cgtgttggtc
    21841 gttcaagtcg tattggttat gcatacttcc tacatccagc aaataaggta ctaactgaga
    21901 ctgcagaaga tcgattacaa gcgattaaag aatttacgga gttaggctca ggatttaaga
    21961 ttgcgatgcg tgatttgaac attcgtggtg ctggtaattt gttaggtaaa caacagcacg
    22021 gctttattga tacagttgga tttgatttgt acagtcaaat gttagaagaa gctgtaaatg
    22081 aaaaacgtgg tattaaggaa ccagaatctg aggtgccaga agtcgaagtt gatttaaact
    22141 tggatgcata tttgccaaca gagtatattg caaatgaaca agctaaaatt gaaatttata
    22201 aaaagctacg aaaaactgaa acatttgatc aaattatcga cattaaagat gaattaattg
    22261 atcgttttaa tgattatcct gttgaagtag cacgtttgct tgatatagtg gaaataaaag
    22321 tacacgcatt acattcaggt atcacgttga ttaaagataa agggaaaata attgatattc
    22381 atttatctgt aaaagccact gaaaatattg atggcgaagt gctgttcaaa gcaacacaac
    22441 ctttaggtag aacaatgaag gttggtgttc aaaataatgc aatgacaatt actttaacga
    22501 aacaaaatca atggcttgat agtttgaatt ttttagttaa gtgcattgaa gaaagtatga
    22561 gaatcagtga tgaagcataa agaagcattt aatggcgttg tcgtgttaac tgctgcatta
    22621 attgtcatta aaattctgag tgctgtatat cgaattccat atcaaaatat attaggcgat
    22681 acaggtttgt atgcatatca acaagtgtat ccaattgtag cactaggaat gatattatcg
    22741 atgaatgcca ttcctagtgc aattacacaa aatataggaa agtatcatag tgacgaagca
    22801 tatgcaaaag cagtcgctta tatacaatta gttggtatat taatatttat tgctattttt
    22861 gtgtttgcga acaatattgc acatatgatg ggtgatggcc atttaacacc aatgattcaa
    22921 gctgcaagtt taagctttat atttataggt atgcttggcg tgttaagagg ttattatcaa
    22981 tctgcaaata atatgacagt tccggctatt tcccaggtta tagaacaagt tatacgagta
    23041 ggtattatca ttgttactat tgttattttt gtagacagag gttggacgat atatgaagcg
    23101 ggaacaattg ctattttagc atcaacgata ggttttttag gttcttcaat ttatttagta
    23161 gcgcaccgac cttttaagtt taaaatggta aataacactg caaagattgt ttggaaacag
    23221 ttcgcacttt cggttttgat tttcgctatc agtcaattaa tcgtaatttt atggcaagtg
    23281 attgatagtg ttactattat taagtcactt caagcgatac gcgtgccatt cgatgttgcc
    23341 ataactgaaa aaggagtcta tgaccgtggt gcatcattta ttcagatggg attgattgta
    23401 actacaacat ttagttttgc gctcattcct ctgttaagtg acgcaatcaa aatgaataat
    23461 caggtactta tgaatcgtta tgcaaatgcg tcattaaaga ttacgatttt aataagtaca
    23521 gcagcgggaa taggattaat taatttattg cctttaatga acggtgtgtt ttttaagacg
    23581 aatgatttaa ccttaacgtt aagtgtttat atgattacgg tcatttgtgt atcgttaatt
    23641 atgatggata tggcattatt acaagcgcaa catgctgtga gacctatttt tgttggtatg
    23701 acggcaggat tggttattaa atttatactt aatatcattt tgattcgttt aagtggcatt
    23761 attggtgcga gcattagtac tgttgtatca ttaattatat tcggtacgat tatccatatt
    23821 gctgtcacga gaaaatacca cttacatgcg atgagacgat tttttatcaa tgttgtttta
    23881 ggtatggtat ttatgtcgat tgttgttcaa tgcgtgttaa acatagtgac aacacacggt
    23941 agaatcactg gactcattga attattatgt gcagcagtat taggtatcat tgcattgttt
    24001 ttctatattt ttagatttaa tgttttgaca tataaagagt taacttattt accatttggt
    24061 tcaaagttgt atcaaattaa gaaaggaaga cgttgatggc acataccatt acgattgttg
    24121 gcttaggaaa ctatggcatt gatgatttgc cgctagggat atataaattt ttaaagacac
    24181 aagataaagt ttatgcaaga acgttagatc atctagttat agaatcattg caagatgaat
    24241 taacatttca gagttttgac catgtttatg aagcacatga ccaatttgaa gatgtctata
    24301 atgatattgt ggcgcaattg gttgaagatg ctaatgaaaa agatattgtc tatgcggttc
    24361 cgggtcatcc tagagttgct gagacaacta cagtgaaatt actggcttta gcaaaggaca
    24421 atactgatat agatgtgaaa gttttaggtg gtaaaagctt tattgatgat gtgtttgaag
    24481 cagttaatgt agatccaaat gatggcttca cactgttaga tgcgacatca ttacaagaag
    24541 taacacttaa tgttagaacg catacattga ttacgcaagt ttatagtgca atggttgctg
    24601 ctaatttgaa aatcacttta atggaacgat atcctgatga ttaccctgtt caaattgtca
    24661 ctggtgcacg aagcgatggt gcggataacg ttgtgacatg cccattatat gaattggatc
    24721 atgatgaaaa tgcattcaat aatttgacga gtgtattcgt accaaaaatc ataacatcga
    24781 catatttgta tcatgacttt gattttgcaa cggaagtgat tgatacttta gttgatgaag
    24841 ataaaggttg tccatgggat aaagtgcaaa cgcatgaaac gctaaagcgt tatttacttg
    24901 aagaaacatt tgaattgttc gaagctattg acaatgaaga tgattggcat atgattgaag
    24961 aactaggaga tattttatta caagtgttat tgcatactag tattggtaaa aaagaagggt
    25021 atatcgacat taaagaagtg attacaagtc ttaatgctaa aatgattcgt agacacccac
    25081 acatatttgg tgatgccaat gctgaaacta tcgatgactt aaaagaaatt tggtctaagg
    25141 cgaaagatgc tgaaggtaaa cagccaagag ttaaatttga aaaagtattt gcagagcatt
    25201 ttttaaattt atatgagaag acgaaggata agtcatttga tgaggccgcg ttaaagcagt
    25261 ggctagaaaa aggggagagt aatacatgag attagataaa tatttaaaag tatcacggtt
    25321 aataaagcga cgtacgctag caaaagaagt aagtgatcaa ggtagaatta caataaatgg
    25381 taatgttgct aaagctggat cggatgttaa agttgaagat gtgctgacga ttcgctttgg
    25441 tcaaaaatta gtaacagtta aagtaactgc attaaatgaa catgcatcta aagataacgc
    25501 gaagggcatg tatgaaatcg ttgaagagcg tcgacttgaa gaagcgtaaa ttggaggtga
    25561 caagcaatga aaaataaagt agaacatata gaaaatcagt acacgtcgca agagaacaag
    25621 aaaaaacaac gtcaaaaaat gaaaatgcgt gttgttcgta ggcgtattac agtatttgcg
    25681 ggcgtattac ttgcgataat tgttgtttta tcaatcttgc ttgttgtcca aaaacatcgc
    25741 aatgatatcg atgcacagga gcgaaaagcg aaagaagcac agtttcaaaa gcaacaaaat
    25801 gaagaaattg cgttaaaaga aaagttgaat aatctgaatg acaaagatta tattgaaaaa
    25861 attgcgcgtg atgattatta cttaagcaac aaaggtgaag tgatttttag gttgccagaa
    25921 gacaaagatt cgtctagctc aaaatcttcg aaaaaataaa tccaaattga ttcaaaatta
    25981 tccgagtata gacattgtga aaaaatccaa acaaggatat aataagggaa aatcgaatca
    26041 aatcgggagg atttatttaa catatgtcaa tcgaagttgg aaataagctt aaaggtaaag
    26101 tcactggtat taaaaagttt ggtgcattcg tagaattacc tgaaggaaaa agtggtttag
    26161 ttcacattag tgaagtcgca gataattatg ttgaaaacgt agaagagcac ctttctgttg
    26221 gtgatgaagt agacgtaaaa gtattatcta ttgctgatga tggaaaaatt agtctttcaa
    26281 ttaagaaagc taaagaccgt ccacgtagac aacatacgag taaaccaagt catcaaaaac
    26341 cagtgcaaaa agccgaagat tttgaaaaga aattaagcaa tttcttaaaa gatagtgaag
    26401 ataaattaac ttcaatcaaa cgtcaaacag aatctagacg cggtggcaaa ggttcaagac
    26461 gttaattaaa ataaataaag actgtttcga taaggaatat atttagaatg atgcgtatcg
    26521 aataatcgat tgcagcgtta gacaatctaa gactgtttct taaataagga gcagtctctt
    26581 ttatttgtaa tgatataact aagacttata ccatttttga aaattgtaaa agtgaggtga
    26641 tgttatgcag ttaaatagta atggttggca tgttgatgac catattgttg tcgctgtttc
    26701 tacaggtatt gatagtatgt gtttattgta tcaactacta aatgattata aagatagtta
    26761 tagaaaacta acatgcttac atgtcaatca tggcgttagg tcagcttcaa tcgaggaagc
    26821 cagattttta gaagtatact gcgaacgtca tcacatcgat ttacatatca aaaagttaga
    26881 tttgtcgcat agtctcgacc gaaataacag cattcagaat gaagctcgaa ttaaacgtta
    26941 cgaatggttt gatgaaatga tgaatgtatt agaagcggat gtattgctaa cggcgcatca
    27001 tttggacgat caattagaaa ctattatgta tcgtattttt aatgggaaat caacacgtaa
    27061 taaactagga tttgatgagt tatcgaagcg aaaaggttat cagatttatc gaccactttt
    27121 agctgtctct aaaaaagaaa taaaacaatt ccaagagaga tatcatattc catattttga
    27181 agatgaatct aataaagata acaaatatgt tagaaatgat attcgtaata gaattattcc
    27241 agctattgat gaaaataatc aacttaaagt atcgcattta ttaaaattaa aacaatggca
    27301 tgatgaacaa tatgatattt tgcaatattc agctaaacaa tttattcaag aatttgtgaa
    27361 gtttgatgaa cagtcaaaat atttagaggt ttctagacaa gcttttaata acttaccaaa
    27421 ctcattaaag atggttgtgt tggattgcct attatcaaag tattatgagt tgtttaatat
    27481 tagtgctaaa acatacgaag agtggtttaa acaatttagt agtaagaaag cacaattcag
    27541 tattaatctc acggataaat ggataattca aatcgcatat ggtaaattaa taataatggc
    27601 taaaaataat ggcgatacat attttagagt tcaaactatt gaaaagccag gtaattatat
    27661 ttttaacaaa tatcgattag agatacattc taatttacca aaatgtttat ttccgcttac
    27721 agtgagaaca cgacaaagtg gcgatacatt taaactgaat gggcgcgatg gttataagaa
    27781 agtgaatcgc ctgtttatag attgtaaagt gcaacagtgg gttcgggatc aaatgccaat
    27841 tgtattggat aaacaacagc gcattattgc ggtaggagat ttatatcaac aacaaacaat
    27901 aaaacaatgg attataatta gtaaaaatgg agatgaatag cgttatgcat aatgatttga
    27961 aagaagtatt gttaactgaa gaagatattc aaaatatctg taaggaattg ggagcacaat
    28021 taacaaagga ttatcaaggt aaaccattag tatgcgtggg tatcttaaaa ggctcagcaa
    28081 tgtttatgtc agatttaatt aaacgaattg atacccattt atcaattgat ttcatggatg
    28141 tttctagtta tcacggaggc actgagtcaa ctggtgaagt tcaaatcatt aaagatttag
    28201 gttcttctat tgaaaataaa gacgtattaa ttattgaaga tatcttagag actggtacta
    28261 cacttaagtc aattactgaa ttattacaat ctagaaaagt taattcatta gaaatagtta
    28321 ctttattaga taaaccaaac cgtcgtaaag cggacattga agctaagtat gtaggtaaaa
    28381 aaataccaga tgaatttgtt gttggttacg gtttagatta tcgtgaatta taccgaaact
    28441 taccatatat cggtacgtta aaacctgaag tgtattcaaa ttaatttttt aatcaatttc
    28501 agttattatt actatgcgtt tgagaaataa tagtgtagac tcaaaaatat gaaaaatgta
    28561 tttcatatat atttaatttt agacaagaca tatgtcttga aaagttgaaa aatatagaga
    28621 ttgataaaac taatacggat gtgaatgaca ttgatgttaa gctcaattac tagcttataa
    28681 aacatgtcat atgttacaat ttttgttagt tttattatgg gaagtaggag gaaatgacgc
    28741 atgcagaaag cttttcgcaa tgtgctagtt atcgtaataa taggcgttat tatttttggt
    28801 ctattttcat atttaaacgg taatggaaat atgccgaaac agcttacata taatcaattt
    28861 actgagaagt tggaaaaagg tgaccttaaa actttagaaa tccaaccaca acaaaatgtc
    28921 tatatggtaa gtggtaaaac gaaaaatgat gaagactatt catcaactat tttatataac
    28981 aacgaaaaag aattacaaaa aattactgat gctgctaaaa agcaaaacgg tgtaaaatta
    29041 acgattaaag aagaagaaaa acaaagtgtc tttgtgagta tactttcaac attaattcca
    29101 gttgtagtca tagcgttatt atttattttc ttcctaagcc aagcacaagg tggcggtagt
    29161 ggcggtcgta tgatgaactt tggtaaatct aaagcaaaaa tgtacgataa taataaacgt
    29221 cgtgttcgtt tctctgatgt agcaggggca gatgaagaaa aacaagaatt aattgaaatt
    29281 gttgatttct tgaaagataa taaaaaattc aaagaaatgg gatctaggat tcctaaaggt
    29341 gtcttacttg ttggacctcc aggtactggt aaaacattac ttgctagagc ggttgcaggt
    29401 gaagctggcg caccattctt ctctattagt ggttcagact ttgtagagat gtttgttggt
    29461 gttggtgcga gccgtgttcg tgacttattc gataatgcta agaaaaacgc gccttgtatt
    29521 atctttatcg atgagattga tgctgttggt cgtcaacgtg gtgcaggtgt tggtggcggt
    29581 catgatgaac gtgaacaaac cctaaaccaa ttattagttg aaatggatgg tttcggtgaa
    29641 aatgaaggta tcattatgat agctgctaca aaccgtcctg atatccttga cccagcctta
    29701 ttacgtccag gtcgttttga tagacaaatt caagttggtc gtccagatgt gaaaggccgt
    29761 gaagcaattc ttcatgttca tgctaaaaac aaaccacttg atgaaacggt tgatttaaaa
    29821 gcaatttcac aacgtacacc tggtttctca ggtgctgatt tagagaactt attaaatgaa
    29881 gcatctttaa ttgctgtacg tgaaggtaaa aagaaaattg acatgagaga tatcgaagag
    29941 gcaacggata gagttatagc cggacctgct aagaaatctc gagttatttc taagaaagaa
    30001 cgtaatattg ttgctcatca cgaagctggt catacaatta tcggtatggt acttgatgag
    30061 gcagaagtag tgcataaagt tactattgtt ccacgtggac aagcaggtgg ttatgcaatg
    30121 atgctaccta aacaagatcg tttcttaatg actgaacaag agttattaga taaaatctgt
    30181 ggtttacttg gtggacgtgt atcagaagat attaacttta acgaagtatc aacaggtgct
    30241 tcaaatgact tcgaacgtgc aacacaaatc gcacgctcaa tggttacgca atatggtatg
    30301 agtaaaaaat taggaccatt acagttcggt catagcaatg gtcaagtatt cttaggtaaa
    30361 gatatgcaag gtgagcctaa ttattcaagc caaatcgcat atgaaattga taaagaagtt
    30421 caacgaatcg ttaaagaaca atacgaacgt tgtaaacaaa ttttattaga gcacaaagaa
    30481 caattaattt taattgctga aacattatta acagaagaaa cattagttgc tgaacaaatt
    30541 caatcattat tctacgaagg taaattacct gaaattgatt atgatgcagc taaagttgtt
    30601 aaagatgaag attctgaatt taatgatggt aaattcggta aatcttatga agagattcgt
    30661 aaagagcaat tagaagatgg acaacgtgac gaaagtgaag atcgtaaaga agaaaaagat
    30721 attgctgagg ataaaaaaga agctgataaa tctgatgaaa aagatgaacc agcacatcga
    30781 caagccccaa atatcgaaaa accttacgat ccaaatcacc cagacaataa ataatcgatt
    30841 atatacagta cctctttcta tgataaagtt atagaaaggg gtacttttat cgtttttgaa
    30901 aatacgtatt agattttaag tcgttgaatt gttatagcag aaaataattg taaaacaagt
    30961 tacttcatta tttagaatga tgggtgtaga ataagaacaa ttgttgcatt ttatgaagta
    31021 aagtaatttt ttaaatatag agtaatagag gagattgaaa taatgacaca cgattatatt
    31081 gttaaagcat tagcatttga tggagagatt agggcttatg ctgctttgac aactgaaact
    31141 gttcaagaag cacaaacgag acattataca tggccgacag catctgctgc aatgggaaga
    31201 acaatgacag caacagctat gatgggcgca atgttgaaag gtgatcaaaa attaactgtc
    31261 actgtagatg gccaaggacc tattggacga attattgccg atgcaaatgc taaaggcgag
    31321 gtgcgtgctt atgtagacca tccacaaact cattttccat taaatgagca aggtaaactt
    31381 gatgtaagac gagcagtagg gacaaatgga tctattatgg ttgttaaaga cgttggaatg
    31441 aaagactatt tctctggagc aagtccaatt gtttcaggag aacttggtga agattttact
    31501 tattattatg ctacaagtga acaaacacct tcatcggtag gtcttggtgt attggtaaat
    31561 cctgataata cgattaaagc agcaggagga tttatcattc aagttatgcc aggtgccaaa
    31621 gatgaaacaa tttcaaaatt agaaaaagca attagtgaaa tgacaccagt ttctaaatta
    31681 attgaacaag gattaacgcc agaaggatta ctaaacgaaa tcttaggtga agaccatgtg
    31741 caaattttag agaaaatgcc tgttcaattt gaatgtaatt gtagtcatga gaaattttta
    31801 aatgctatta aaggattggg cgaggctgag attcaaaata tgattaaaga agatcatggt
    31861 gctgaagcag tatgtcattt ctgtggaaat aaatataaat atactgaaga agaattaaac
    31921 gtgttgctag aaagtttagc gtaatttaat ttaaatcaat acgctaaaat gtttattttt
    31981 agcggtttag tgaaatgtag aactaaatag ttgtataatc cttagtaatt ttgtttgctt
    32041 tctagaattt atttgataaa ataattctat atccgataaa taaactaaga tttcaacaac
    32101 taactaaaaa ggagtgttct taatggcaca aaaaccagta gataatatta ctcaaattat
    32161 tggcgataca ccggtagtca aattgagaaa tgtagtagat gacaatgcag cagatgttta
    32221 tgtaaaattg gaatatcaaa atccaggtgg ttctgtaaag gatagaattg ctttagcaat
    32281 gattgaaaaa gcagagcgag aaggcaaaat taaacctggc gatacaattg tagaaccaac
    32341 tagtggtaat acgggtatcg gtttagcatt tgtatgtgct gctaaaggat ataaagcagt
    32401 atttactatg cctgaaacaa tgagccaaga gcgtcgtaat ttattaaaag catacggtgc
    32461 ggaattagtt ttaacgcctg gatcagaagc gatgaaaggt gcaattaaaa aagctaaaga
    32521 attaaaagaa gaacatggtt acttcgagcc acaacaattt gaaaaccctg cgaaccctga
    32581 agttcatgag ttaactacag gtcctgagtt attacaacaa tttgaaggga aaactatcga
    32641 tgcgttccta gctggtgttg gtactggtgg tacgttatct ggtgtaggta aagttctgaa
    32701 aaaagaatat cctaacatcg aaattgttgc tatagagcct gaggcttctc cagtattgag
    32761 cggtggtgag ccaggtccac ataaattaca aggtttaggt gctggattta ttccaggcac
    32821 tttgaataca gaaatctatg acagtattat taaagtagga aatgatacag cgatggaaat
    32881 gtctcgtcga gttgctaaag aggaaggtat tttagcaggt atttcatcag gtgctgcgat
    32941 ttatgctgcc attcaaaaag caaaagaatt aggaaaaggt aaaacagtag taacagtatt
    33001 gccgagtaat ggtgaacgct acttatcaac acctttatat tcattcgatg actaattaat
    33061 gtcatttaaa agagtgagtt atctttttga gataacttgc tctttttttc taccatgtat
    33121 aattttaaaa atatgagcgt taaattaaac atttttctga taaaaacatc cagtgaatga
    33181 taagataata aacgtacata ctaataacta gtaaatcgca ggagtaaatt ttattagagt
    33241 taaacaatac ataattaaag ggtggttaac atgactaaaa caaaaattat gggcgtatta
    33301 aacgtcacac ctgattcatt ctcagatggt ggaaaattta ataatgttga atcagcagta
    33361 actagagtga aagcgatgat ggatgaaggt gctgacatta tagatgttgg aggtgtttca
    33421 acgagacccg gccatgaaat ggtttcatta gaagaagagc tgaacagagt attacctgtt
    33481 gttgaagcta ttgtcggttt tgatgtgaaa atttcagtcg atacatttcg aagtgaggtt
    33541 gctgaagcat gtttaaaatt aggcgttgat atcattaatg atcaatgggc ggggctgtat
    33601 gatcatcata tgttccaaat tgtagctaaa tatgacgcgg aaattatttt aatgcataat
    33661 ggaaatggta atcgtgatga accggttgtc gaagaaatgt taacatcttt gttagcacaa
    33721 gcacatcaag ctaaaatagc tggtatacct tcaaataaaa tttggctaga tccaggtata
    33781 ggtttcgcta aaactagaaa tgaagaagcc gaagttatgg caagactgga tgaacttgtt
    33841 gcaacagaat atccagtttt attagcgaca agccggaaac gtttcactaa agagatgatg
    33901 ggttatgata caacaccggt tgaaagagat gaagtaactg cagctacgac tgcatatggt
    33961 attatgaaag gcgttagagc agtacgcgtt cataatgtcg agttgaatgc taaattagct
    34021 aaaggtatag attttttaaa ggagaatgaa aatgcaagac acaatctttc ttaaaggtat
    34081 gcgcttttat ggatatcatg gtgctttatc agctgaaaat gaaatagggc aaattttcaa
    34141 agtggatgta actttgaaag tagacttagc tgaagctggg cgtactgata atgttattga
    34201 tacagttcat tatggtgaag tgttcgaaga ggttaaatca attatggaag gtaaggccgt
    34261 taatttactt gagcatctag ctgaacgtat tgcaaatcgt ataaattcac aatataatcg
    34321 tgtaatggaa acgaaagtga gaatcactaa agaaaaccca ccgattccgg gtcattatga
    34381 tggagtaggt atcgaaatag tgagggagaa taaatgattc aagcatactt aggattaggt
    34441 agtaatattg gtgatagaga aagccagtta aacgatgcta taaagatttt gaatgaatat
    34501 gatggtatta acgtatctaa tatttctccg atttatgaaa cagcaccagt tgggtatact
    34561 gagcaaccta actttttaaa tttgtgtgtt gaaattcaaa caacactcac agtattacaa
    34621 ctgttggaat gttgtttgaa gacagaagaa tgtttacacc gtgttagaaa ggaacgatgg
    34681 ggtcctagaa ctttagatgt ggatattttg ttgtatggag aagaaatgat agatttacca
    34741 aaactgtcgg tgccacatcc gagaatgaat gaacgtgcat ttgttttaat cccattaaat
    34801 gatatagcag caaatgtcat agaaccacgt tcgaaattga aagtgaaaga tttagttttt
    34861 gtcgatgaca gtgtaaagag atataaataa tgtattgttg agaacattca tatttattgg
    34921 gaatagatga ttgattattg gagatgtttc cgcattttga ttatctctaa atgcatttga
    34981 tttcgaatta gtatatgatg attcagtatg tgttagaatt aagttatttc ataaaatcaa
    35041 agtaagcaat atttgataaa ttgctgtaat gtatttgggc ttttgttgaa gtttgtggaa
    35101 gataattttt atacatttac ttagggttgt attaatgata atcgtatttt aaatgaataa
    35161 gtaattcata aacgaaaaca gaaattgctt tattacattt acaacctctt gtaaaattaa
    35221 aaaagtgata aaattgatgt tatgaatata agaaaacatg ccacatcata actttaaggt
    35281 gtaatggtta atgataaagt attagaaaca tcgaaagaga tgtatgttga gcaaaaatgt
    35341 ctgatatttt ataaaacttt aaaggaaaat gtttgagtgt accagttgga atactaaagg
    35401 attacaacaa gttaaaggag agaaagttat gtcagaagaa atgaatgacc aaatgttggt
    35461 tcgacgtcaa aaattacaag aattatatga tcttggtata gacccgtttg gttctaaatt
    35521 tgaccgttca ggtttatcta gtgatttgaa agaagagtgg gaccagtatt ctaaagaaga
    35581 attggtagaa aaagaagcgg atagtcatgt cgctatagct ggacgattaa tgactaagcg
    35641 tggtaaaggt aaagcaggat ttgcacacgt tcaggactta gctggacaaa ttcaaattta
    35701 cgttcgtaaa gatcaagttg gcgatgacga atttgattta tggaaaaatg ctgatttagg
    35761 cgatatcgtt ggtgttgaag gtgtaatgtt caaaacaaat actggcgaat tatcggttaa
    35821 agcgaagaaa ttcacgctac taactaaatc attgcgacca ttaccagata aattccacgg
    35881 tttacaggat attgaacaga gatatcgtca aagatattta gatttaatta cgaacgaaga
    35941 tagcactcgt acatttatta atcgtagtaa aatcattcaa gaaatgcgta attatttaaa
    36001 taataaaggt ttcttggaag tagaaacacc tatgatgcac caaattgctg gtggcgcagc
    36061 tgctagacca tttgtaacac atcataatgc attagatgca acgttataca tgcgtattgc
    36121 tattgagttg catttaaaac gtttaattgt cggtggactt gaaaaagtat atgaaattgg
    36181 tagagtattc cgtaatgaag gtgtatcaac tagacataac cctgaattca caatgattga
    36241 attatatgaa gcatatgcag attatcatga cattatggat ttaacagaat ctatggtgag
    36301 acatattacc aatgaagtat taggttctgc aaaagtacaa tacaatgggg aaacgattga
    36361 tttagaatct gcttggactc gtttgcatat tgttgatgct gtaaaagaag ctactggtgt
    36421 agatttttat gaagttaaaa gtgatgaaga agctaaagct ttagctaaag aacatggtat
    36481 tgaaattaaa gatacaatga aatatggtca tattttaaat gaattctttg agcaaaaagt
    36541 tgaagaaaca cttattcagc caacgtttat ctatggtcat ccgactgaaa tttcaccttt
    36601 agcgaagaaa aatcctgaag atcctagatt tactgatcgt ttcgaattgt tcattgtagg
    36661 tagagagcat gcaaatgcat ttactgaatt aaatgatcct attgatcaaa aaggtcgttt
    36721 tgaagcgcaa cttgttgaaa aagcgcaagg taatgatgaa gcgcatgaaa tggatgaaga
    36781 ttacattgaa gcgttagaat atggtatgcc tccgacaggt ggtcttggta tcggtattga
    36841 tagattggtt atgttattaa ctgactctcc atcaatcaga gacgtgttat tattccctta
    36901 tatgagacaa aaataaatga cgttgattgt tagtaagagc tctcgtgtat acaacatgtg
    36961 tatgcgaggg ttttcttaat tatggtaatt agttcgtgtt tgaatgtttt tgatagtaat
    37021 agttaacgat aatggtgcta tttttgactg ttaaacaagg tagttggctg atagatgaaa
    37081 atgacgatac gtatatagag tagttcggat gagaaatgtt aacgatagac attgagatat
    37141 cttataacaa aaattgctat attagtataa tttatcttaa tcagctataa aagtacttta
    37201 aaattgtata gaatgtgtat ggttttgtac atatgtgtat gatagaatac taaaagtgtt
    37261 atgaattaga gagcacgaga aatgtcagtt ttgaagaata aaaaagttga ttaaaagtgt
    37321 tgactttatc aattgaatga agtaatatat aaaagtcgtc aaaaacagac gaaacacact
    37381 aaaagctgat gtgacaaagt tcacaacaaa gtgtaaaatt aactattgca ccttattaat
    37441 taagcgtgta tcataaatta gtaagttatt ttgtctggtg actatagcaa ggaggtcaca
    37501 cctgttccca tgccgaacac agaagttaag ctccttagcg tcgatggtag tcgaacttac
    37561 gttccgctag agtagaacgt tgccaggcaa atgacaaatc ggagaattag ctcagctggg
    37621 agagcatctg ccttacaagc agagggtcgg cggttcgaac ccgtcattct ccaccattta
    37681 ttcttagata tagccggcct agctcaattg gtagagcaac tgacttgtaa tcagtaggtt
    37741 gggggttcaa gtcctctggc cggcaccatc ttttgagcca ttagctcagc tggtagagca
    37801 tctgactttt aatcagaggg tcagaggttc gaatcctcta tggctcatta cgatttaatt
    37861 tttatattta gcaaaataat gcagaagtag ttcagcggta gaatacaacc ttgccaaggt
    37921 tggggtcgcg ggttcgaatc ccgtcttctg ctccattatt ttgccggggt ggcggaactg
    37981 gcagacgcac aggacttaaa atcctgcggt gagagatcac cgtaccggtt cgattccggt
    38041 cctcggcacc attttagcgc ccgtagctca attggataga gcgtttgact acggatcaag
    38101 aggttatggg ttcgactcct atcgggcgcg ccatttttaa attaattgaa taacgggaag
    38161 tagctcagct tggtagagca cttggtttgg gaccaagggg tcgcaggttc gaatcctgtc
    38221 ttcccgatta cttcttaaat tccattttat gggggcttag ctcagctggg agagcgcctg
    38281 ctttgcacgc aggaggtcag cggttcgatc ccgctagtct ccaccattta ttttttacac
    38341 gatgaacatt gaaaactgaa tgacaatatg tcaacgttaa ttcc
//
LOCUS       DAPSKH010000020        38143 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPSKH010000020 DAPSKH010000000
VERSION     DAPSKH010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 38143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38143
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.020"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(88..1047)
                     /locus_tag="RPH49_001121"
     CDS             complement(88..1047)
                     /locus_tag="RPH49_001121"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDY5124289.1"
                     /translation="MKTFGKKVVLIGDGSVGSSYAFAMVTQGVADEFVIIDIAKDKVK
                     ADVQDLNHGTVHSPSPVDVKAGEYEDCKDADLVVITAGAPQKPGETRLQLVEKNTKIM
                     KSIVKSVMDSGFDGYFLIAANPVDILTRFVKEYTGLPAERVIGSGTVLDSARLQYLIS
                     QELGVAPSSVDASIIGEHGDTELAVWSQANVAGISVYDTLKEQTGSEAKAEEIYVNTR
                     DAAYEIIQAKGSTYYGIALALMRISKAILNNENNVLNVSIQLDGQYGGHKGVYLGVPT
                     LVNQHGAVKIYEMPLSAEEQALFDKSVKTLEDTFDSIKYLLED"
     gene            1734..3182
                     /locus_tag="RPH49_001122"
     CDS             1734..3182
                     /locus_tag="RPH49_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5124290.1"
                     /translation="MGSFFNKIARKEDPAIYQNKDGHLKRTLRVRDFLALGVGTIVST
                     SIFTLPGIVAAQHAGPAVALSFLLAAIVAGLVAFTYAEMAAAMPFAGSAYSWVNVLFG
                     EFFGWVAGWALLAEYFIAVAFVASGFSANLRGLVKPIGIELPAALSNPFGTNGGFIDI
                     IAAIVILLTALLLSRGMSEAARMENILVILKVLAIILFVIVGLTAINVSNYVPFIPEH
                     KVTATGDFGGWQGIYAGVSMIFLAYIGFDSIAANSAEALDPQKTMPRGILGSLSVAIV
                     LFIAVALVLVGMFHYSQYANNAEPVGWALRQSGHGVVAAIVQAISVIGMFTALIGMML
                     AGSRLLYSFGRDGLLPSWLSHLNDKHLPNRALVILTIIGVLIGSMFPFAFLAQLISAG
                     TLVAFMFVSLAMYRLRKREGKDLPIPAFKLPLYPVLPAVTFVLVLLVFWGLGFEAKLY
                     TLIWFIVGIILYLSYGLRHSKKNDVAEYHPPK"
     gene            complement(3262..4599)
                     /locus_tag="RPH49_001123"
     CDS             complement(3262..4599)
                     /locus_tag="RPH49_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase family protein"
                     /protein_id="HDY5124291.1"
                     /translation="MSKAHQLIQEDEHYFAKSGRIKYYPLVIDHGYGATLVDIEGKTY
                     IDLLSSASSQNVGHAPREVTEAIKAQVDKFIHYTPAYMYHEPLVRLAKKLCQIAPGDF
                     EKRVTFGLTGSDANDGIIKFARAYTGRPYIISFTNAYHGSTFGSLSMSAISLNMRKHY
                     GPLLNGFYHIPFPDKYRGMYEQPQANSVEEYLAPLKEMFAKYVPADEVACIVIETIQG
                     DGGLLEPVPGYFETLEKICREHGILIAVDDIQQGFGRTGTWSSVSHFNFTPDLITFGK
                     SLAGGMPMSAIVGRKEIMNCLEAPAHLFTTGANPVSCEAALATIQMIEDQSLLQASAE
                     KGEYVRKRMDQWVSKYNSVGDVRGKGLSIGIDIVSDKKLKTRDASAALKICNYCFEHG
                     VVIIAVAGNVLRFQPPLVITYEQLDTALNTIEDALTALEAGNLDQYDISGQGW"
     gene            4857..5273
                     /locus_tag="RPH49_001124"
     CDS             4857..5273
                     /locus_tag="RPH49_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124292.1"
                     /translation="MRLKVLFHFIAAIFISFMLLWMTMLFDLISNQSHLKALLLNLDF
                     LIPSDNTPYILEIICHLLIGSVIYFIFVLLFHTSKRLYYLCYIPLFFLFIALYPFLVF
                     IAQRPIFQFSVTELIGWIITHIFFMSLIALVIPRIK"
     gene            5396..6286
                     /locus_tag="RPH49_001125"
     CDS             5396..6286
                     /locus_tag="RPH49_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002478556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose bisphosphate aldolase"
                     /protein_id="HDY5124293.1"
                     /translation="MNKEQLEKMKNGKGFIAALDQSGGSTPKALKEYGVNEDQYSNED
                     EMFQLVHDMRTRVVTSPSFSPDKILGAILFEQTMDREVEGKYTADYLADKGVVPFLKV
                     DKGLAEEQNGVQLMKPIDNLDSLLDRANERHIFGTKMRSNILELNEQGIKDVVEQQFE
                     VAKQIIAKGLVPIIEPEVNINAKDKAEIEKVLKAELKKGLDSLNADQLVMLKLTIPTE
                     PNLYKELAEHPNVVRVVVLSGGYSREKANELLKDNAELIASFSRALASDLRADQSKEE
                     FDKALGDAVESIYDASVNKN"
     gene            complement(6478..7974)
                     /gene="mqo"
                     /locus_tag="RPH49_001126"
     CDS             complement(6478..7974)
                     /gene="mqo"
                     /locus_tag="RPH49_001126"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDY5124294.1"
                     /translation="MAKSNSKDIVLIGAGVLSTTFGSMLKEIEPDWNIHVYERLDRPA
                     IESSNERNNAGTGHAALCELNYTVLQPDGSIDIEKAKVINEEFEISKQFWGHLVKSGS
                     IENPREFINPLPHISYVRGKNNVKFLKDRYEAMKAFPMFDNIEYTEDIEVMKKWIPLM
                     MKGREDNPGIMAASKIDEGTDVNFGELTRKMAKSIEAHPNATVQFNHEVVDFEQLSNG
                     QWEVTVKNRLTGEKFKQVTDYVFIGAGGGAIPLLQKTGIPESKHLGGFPISGQFLACT
                     NPQVIEQHDAKVYGKEPPGTPPMTVPHLDTRYIDGQRTLLFGPFANVGPKFLKNGSNL
                     DLFKSVKTYNITTLLAAAVKNLPLIKYSFDQVIMTKEGCMNHLRTFYPEARNEDWQLY
                     TAGKRVQVIKDTPEHGKGFIQFGTEVVNSQDHTVIALLGESPGASTSVSVALEVLERN
                     FPEYKTEWAPKIKKMIPSYGESLIEDEKLMRKIRKQTSKDLELGYYEN"
     gene            8270..8601
                     /locus_tag="RPH49_001127"
                     /pseudo
     CDS             8270..8601
                     /locus_tag="RPH49_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501381.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8661..10259)
                     /locus_tag="RPH49_001128"
     CDS             complement(8661..10259)
                     /locus_tag="RPH49_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl--CoA ligase"
                     /protein_id="HDY5124295.1"
                     /translation="MQKSALFAPEKYNIISEIEKYSHIPDKKAILYHNTEGEDISVTY
                     QQLIEQSNKVGNVLASHGLSKGDKVLIMMPRSIATYELYIAALKLGVAIIPCSEMLRT
                     KDLQYRITHGEINAVIALEPFTVEFEKIKGYDALTKFVIAGQKDGWISLEAEKENASN
                     KLEMADTTRDDTAILSYTSGTTGNPKAVTHCHGWGFAHLQMAPKHWLCINEDDLVWAT
                     AAPGWQKWVWSPFLSVLGSGATAFVFNGRFSPETYLELLQKYQINVLCCTPTEYRMMA
                     KLQNLNDYDLTHLHSAVSAGEPLNREVVEQFKKYFNLTVRDGYGQTESTLLIGFLKDT
                     PQRIGSMGKGIPGSSVTVVDDEGNSVPANTEGNIAVPLDLPALFKGYYKEPERTAKAQ
                     TGKYYITGDLAHVDDDGYFWFEGRRDDIIISSGYTIGPFEVEDALTNHPAVKECAVVA
                     KPHDIRGNIVKAFVILQDHTAGDDTLVKELQQFVKNEVAPYKYPREIEFVDDLPKTNS
                     GKIRRVELRDAEIEKWQQQKDSNQ"
     gene            complement(10453..10896)
                     /locus_tag="RPH49_001129"
     CDS             complement(10453..10896)
                     /locus_tag="RPH49_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDY5124296.1"
                     /translation="MNIYDEYRSYVIEELDDCLTIQKNNDTAYYDVLEAINDLSNDSL
                     CVLNHLYINEGQEETFEQKFLRRNKHLKNVDGFKALRFLRPRTAGRHYIIITLWENRK
                     AFYHWQNSAEYKHTHKHRGTSKGADVKIINRELSYNIRIELADMV"
     gene            complement(11176..11388)
                     /locus_tag="RPH49_001130"
     CDS             complement(11176..11388)
                     /locus_tag="RPH49_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDY5124297.1"
                     /translation="MSFYEYIQTFKDDKTPLGELAIWIKEDDSFPKQEKLTENILSYF
                     HQMSNIDHEFLEIVKRSLSLYDQLKS"
     gene            complement(11665..13374)
                     /gene="betA"
                     /locus_tag="RPH49_001131"
     CDS             complement(11665..13374)
                     /gene="betA"
                     /locus_tag="RPH49_001131"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDY5124298.1"
                     /translation="MSNKNKSYDYVIIGGGSAGSVLGNRLSEDKDKEVLVLEAGRSDY
                     FWDLFIQMPAALMFPSGNKFYDWIYSTDEEPHMGGRKVAHARGKVLGGSSSINGMIYQ
                     RGNPMDYEGWAEPEGMETWDFAHCLPYFKKLEKTYGAAPYDKFRGHDGPIKLKRGPAT
                     NPLFQSFFDAGVEAGYHKTPDVNGFRQEGFGPFDSQVHRGRRMSASRAYLHPAMKRKN
                     LTVETRAFVTEIHYEGRRATGVTYKKNGKLHTIDANEVILSGGAFNTPQLLQLSGIGD
                     SEFLKSKGIEPRVHLPGVGENFEDHLEVYIQHKCKEPVSLQPSLDIKRMPFIGLQWIF
                     TRKGAAASNHFEGGGFVRSNNEVDYPNLMFHFLPIAVRYDGQKAAVAHGYQVHVGPMY
                     SNSRGSLKIKSKDPFEKPSIRFNYLSTEEDKKEWVEAIRVARNILSQKAMDPFNGGEI
                     SPGPEVQTDEEILDWVRRDGETALHPSCSAKMGPASDPMAVVDPLTMKVHGMENLRVV
                     DASAMPRTTNGNIHAPVLMLAEKAADIIRGRKPLEPQYIDYYKHGVHDENEGAIEVKP
                     YAK"
     gene            complement(13635..15125)
                     /gene="betB"
                     /locus_tag="RPH49_001132"
     CDS             complement(13635..15125)
                     /gene="betB"
                     /locus_tag="RPH49_001132"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDY5124299.1"
                     /translation="MELLKHLSQRQYIDGEWVESANKNTRDIINPYNQEVIFTVSEGT
                     KEDAERAILAARRAFESGEWSQETAETRGKKVRAIADKIKEHREALARLETLDTGKTL
                     EESYADMDDIHNVFMYFAGLADKDGGEMIDSPIPDTESKIVKEPVGVVTQITPWNYPL
                     LQASWKIAPALATGCSLVMKPSEITPLTTIRVFELMEEVGFPKGTINLILGAGSEVGD
                     VMSGHKEVDLVSFTGGIETGKHIMKNAANNVTNIALELGGKNPNIIFDDADFELAVDQ
                     ALNGGYFHAGQVCSAGSRILVQNSIKDKFEQALIDRVKKIKLGNGFDADTEMGPVIST
                     EHRNKIESYMDVAKAEGATIAVGGKRPDRDDLKDGLFFEPTVITNCDTSMRIVQEEVF
                     GPVVTVEGFETEQEAIQLANDSIYGLAGAVFSRDIGKAQRVANKLKLGTVWINDFHPY
                     FAQAPWGGYKQSGIGRELGKEGLEEYLVSKHILTNTNPQLVNWFSK"
     gene            15194..15289
                     /locus_tag="RPH49_001133"
     CDS             15194..15289
                     /locus_tag="RPH49_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124300.1"
                     /translation="MKNVSIYKTTKELSFVSSLDFYLTKHLTLML"
     gene            15378..15941
                     /locus_tag="RPH49_001134"
     CDS             15378..15941
                     /locus_tag="RPH49_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GbsR/MarR family transcriptional regulator"
                     /protein_id="HDY5124301.1"
                     /translation="MTRSQNKQQQLEQAKDIVINSIGQTMDLYGTNRSVGNLYGTMVF
                     EGSMTLDEMRHQLQMSKPSMSAGVKKLQEFDIVKQQFTRGSRKQHFIAEKDFFIFFRN
                     FFTKKFQREIDINVEAVKDAQAIINPLLESSDLTEAETQEAQKIKAQLDHTHVYYEWL
                     EQLTEAIESGEIFKYFPIPEQPSDSEN"
     gene            complement(16111..17733)
                     /locus_tag="RPH49_001135"
     CDS             complement(16111..17733)
                     /locus_tag="RPH49_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501390.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDY5124302.1"
                     /translation="MKKEKVMDWTTFIGTVAVLLFAVIPMMAFPKASEDIITGINSAI
                     SDSIGSIYLFMGLAIFCFVMYIAFGKYGNVTLGKASDKPEFNTFTWAAMLFCAGIGSD
                     ILYWGVIEWAFYYQVPPNGAKSMSDEALQYATQYGMFHWGPIAWAIYVLPALPIGYLV
                     FVKKQPVYKISQACRPILKGQTDKFVGKVVDILFIFGLLGGAATSLALGVPLISAGIE
                     RLTGLDGKNMILRSAILLTITVIFAISSYTGLKKGIQKLSDINVWLSFVLLAFIFIIG
                     PTVFIMETTVTGFGNMLRDFFHMATWLEPFGGIKGRKETNFPQDWTIFYWSWWLVYAP
                     FIGLFIARISKGRRLKEVVLGTIIYGTLGCVLFFGIFGNYAVYLQISGQFNVTQYLNT
                     HGTEATIIEVVHHLPFPSLMIVLFLVSAFLFLATTFDSGSYILAAASQKKVVGEPLRA
                     NRLFWAFALCLLPFSLMLVGGERALEVLKTASILASVPLIVIFIFMMISFLIILGRDR
                     IKLETRAEKLKEVERRSLRIVQVSEEEQDDNL"
     gene            17865..18026
                     /locus_tag="RPH49_001136"
     CDS             17865..18026
                     /locus_tag="RPH49_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124303.1"
                     /translation="MAIIEYLYNFSRNKQNLNSAKTTVLSYDLTNLTNFTRMAFKNIY
                     TLLTNIYLL"
     gene            complement(18042..18152)
                     /locus_tag="RPH49_001137"
     CDS             complement(18042..18152)
                     /locus_tag="RPH49_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124304.1"
                     /translation="MIEYDLTIILIPILKVAYPFFKKVERKKWYFSGKEV"
     gene            complement(18252..18788)
                     /gene="nrdG"
                     /locus_tag="RPH49_001138"
     CDS             complement(18252..18788)
                     /gene="nrdG"
                     /locus_tag="RPH49_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDY5124305.1"
                     /translation="MTLLDIKQGQGYIAKIESNSFVDGEGVRCSVYVSGCPFNCVGCY
                     NKASQKFRYGEKYTDEILAEILDDCDHDYISGLSLLGGEPFCNLDITLNLVKAFRARF
                     GNTKTIWVWTGFLYEYLANDCAERRELLSYIDVLVDGLFIQHLFKPDLPYKGSLNQRI
                     IDVQQSLSHARMIEYIVS"
     gene            complement(18785..20635)
                     /gene="nrdD"
                     /locus_tag="RPH49_001139"
     CDS             complement(18785..20635)
                     /gene="nrdD"
                     /locus_tag="RPH49_001139"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDY5124306.1"
                     /translation="MNQIEEALTGLISKDPAIVNENANKDSDTFSTMRDLTAGIVSKS
                     YALNHLLPKHVADAHQRGDIHFHDLDYHPFQPLTNCCLIDAKNMLHNGFEIGNANVTS
                     PKSIQTASAQLVQIIANVSSSQYGGCTVDRVDELLSTYARHNEEQHRNIAKQFVKESE
                     IDRYVDQQVTKDINDAIESLEYEINTLYTSNGQTPFVTLGFGLGTDHLSRKIQQAILN
                     TRIKGLGKDRTTAIFPKLVFSIKKGTNFSPQDPNYDIKQLALKCSTKRMYPDILNYDK
                     LVEILGDFKAPMGCRSFLPSWKDAEGHFENNGRCNLGVVTLNLPRMALESAGNMTKFW
                     EIFYERIDVLHDALLYRINRLKDAVPNNAPILYKSGAFNYKLKETDDVAELFKNKRAT
                     ISMGYIGLYETATVFYGPDWETSQEAKAFTLEILKEMKRYQTKWTELYDIWFSIYSTP
                     SESLTDRFCRLDQERFGDIKDITDKGYYQNSFHYDVRKDVTPFEKLDFEKDYPYYASG
                     GFIHYCEYPKLQHNLKALEAVWDYSYDKVGYLGTNIPIDHCYECDYDGDFEATEKGFK
                     CPNCGNDNPKTVDVVKRTCGYLGNPVQRPVIKGRHKEICARVKHMKAPKE"
     gene            complement(20881..22251)
                     /locus_tag="RPH49_001140"
     CDS             complement(20881..22251)
                     /locus_tag="RPH49_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CitMHS family transporter"
                     /protein_id="HDY5124307.1"
                     /translation="MNSDNMWLTVMGLIIIISIVGLLIAKKINPVVGMTIIPCLGAMI
                     LGYSVTDLVGFFAKGLDQVINVVIMFIFAIIFFGIMNDSGLFKPLVKRLILMTRGNVV
                     IVCAMTALIGTIAQLDGAGAVTFLLSIPALLPLYKALNMNKYLLILLLALSAAIMNMV
                     PWGGPMARVAAVLKAKSVNELWYGLIPIQIIGFILVMLFAVYLGFKEQKRIKKAIERN
                     ELPQTQDIDVHKLVEVYERDQDVRFPVKGRARTQPWIKWVNTALTLAVILAMLMNIAP
                     PEFAFMIGVSLALIINFKSVDEQMERLRAHAPNALMMAAVIIAAGMFLGVLNETGMLK
                     AIATNLIKVIPAEVGPYLHIIVGLLGVPLDLLTSTDAYYFAVLPIVEQTAGQFGVPSV
                     STAYSMVIGNIIGTFVSPFSPALWLAIGLAEANMGTYIKYAFFWIWGFAIVMLVIAML
                     MGIVTI"
     gene            complement(22573..22668)
                     /locus_tag="RPH49_001141"
     CDS             complement(22573..22668)
                     /locus_tag="RPH49_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124308.1"
                     /translation="MGGFVNSLIMKYLSDNDMRFKYEYYNREKDT"
     gene            complement(22733..23341)
                     /locus_tag="RPH49_001142"
     CDS             complement(22733..23341)
                     /locus_tag="RPH49_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding protein"
                     /protein_id="HDY5124309.1"
                     /translation="MNMPLMINLTNKNVVIVGGGVVASRRAQTLSQYVEHMTVISPTI
                     TEKLQNMVDNGVVIWKEKEFEPSDIVDAYLVIAATNEPRVNEAVKQALPEHALFNNVG
                     DASNGNVVFPSALHRDKLTISVSTDGASPKLTKSIMAELEALYPPSYSSYIDFLYTCR
                     QKIKLLDITYNEKQQLLSQIVSQEYLNHDKQAQFLAWLDVRQ"
     gene            complement(23407..25287)
                     /locus_tag="RPH49_001143"
     CDS             complement(23407..25287)
                     /locus_tag="RPH49_001143"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     flavoprotein subunit"
                     /protein_id="HDY5124310.1"
                     /translation="MKLNTSNSPFTEKQVTEINNLLQTLTESQQQWLSGFLLANSSDT
                     TSDSNQQQLETEVWQQSQISEEQATSTTYMLQNKEPHIEANQRHVTVLYGSESGNAMR
                     LAEIFSERLSDIGHQVVLMSMDEYDTTNIAQLEDLFIITSTHGEGEPPDNAWDFFEFL
                     EDDNAPNLNHVRYSVLALGDQTYEFFCQAGKDVDALLENLGAERICKRVDCDIDYEED
                     AEKWMADIINMIDTTSEGIQSESVISESIKSAKEKKYSKSNPYQAEVLANINLNGTDS
                     NKETRHIEFLLDDFSESYEPGDCIVALPQNDPELVEKLISMLGWDPQSPVPINDHGDT
                     VPIVEALTSHFEFTKLTLPLLKNADIYFDNEELSERIQDESWAREYVINQDFIDLITD
                     FPTIELQPENMYQILRKLPPREYSISSSFMATPDEVHITVGTVRYQAHGRERKGVCSV
                     HFAERIKPGDIVPIYLKKNPNFKFPMKQDIPVIMIGPGTGIAPFRAYLQEREELGMTG
                     KTWLFFGDQHRSSDFLYEEEIEEWLENGNLTRVDLAFSRDQEHKEYVQHRIMEESERF
                     NEWIEQGAAIYICGDEKCMAKDVHQAIKDVLVKERHISQDEAETILRQMKQQQRYQRD
                     VY"
     gene            25478..25566
                     /locus_tag="RPH49_001144"
                     /pseudo
     CDS             25478..25566
                     /locus_tag="RPH49_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501399.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(25674..26171)
                     /locus_tag="RPH49_001145"
     CDS             complement(25674..26171)
                     /locus_tag="RPH49_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDY5124311.1"
                     /translation="MNNRNVYDIEVSDYKGLTYKLEAFRSKVILVVNTATECIYSEQL
                     KKLETLFQKYKDRGFVVLSFPNNNFDNRQPGSNEEILKISREKFGVTFPVLAKISVNG
                     NDEHPLFTHLKNEQPGIFGSPIKWNFTKFIIDRQGNVVNRFLPMEDPLDISANIEILL
                     QESSS"
     gene            complement(26181..26441)
                     /locus_tag="RPH49_001146"
     CDS             complement(26181..26441)
                     /locus_tag="RPH49_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124312.1"
                     /translation="MIIMRGYNERYCSWTNTAIQCDYFNKVRQVKKDGKSDRLSNNIN
                     SNIIYRVFEKCIALYNVYSRCKRALILSEHSKKNIFNIKKAV"
     gene            complement(26823..26936)
                     /locus_tag="RPH49_001147"
     CDS             complement(26823..26936)
                     /locus_tag="RPH49_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124313.1"
                     /translation="MNGILIKCLNIGGQYYLQTRMLSNVDNAEKTISGNSI"
     gene            complement(27600..29600)
                     /locus_tag="RPH49_001148"
     CDS             complement(27600..29600)
                     /locus_tag="RPH49_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124314.1"
                     /translation="MKLRLLWHIVRRQFITQRLVIIPFILAVSVLFMIEYTLVSIGLN
                     SYIKQKNDFLVPFIIIANFFMALLTFIFIFYANHFMMSQRRKEFSIFMTLGMTKKSMR
                     LIVVMETILQFMIISVVSIAGGYLLGAIFFLFIQKIMGSEVATLRYYPFDSVAMFITL
                     IIIAVLMGMLLIFNLFSINFQRPITYQHRSDSSVISRWLRYVLIVIGSAALYLGYFIA
                     LQQDTTFGAFFKIWIVIGFVIIGTYAFFVGISEIIISILQQVSKVYYHPRYFFVVVGM
                     RVRLKMNAVSLATITLLCTFLIVTLTMTLTTYRDMNHTIMKLITNDYDLSFNDNSKSQ
                     IERQQMIENIKRDIQGSVNAKDFKVYETTLFRASLEKNRAYYKLKQASDDIPIDFIGN
                     EGSIFSKQSVMITALTVQDYNRYHQNKLHLDNQSIGMITNVPIFKKQSKVGLNNEVFK
                     VKQLDAHALNLMMIQDSMVLIVKDNNQLQKVKRFYAHEQKKSTISINFNVSGKTKLTT
                     SQIQKLSKKYDASINSKSEMLMVWDRLTGGLIFVGGVVSIVLVIGIFLMMYYKQVSEA
                     YANQHNYDIMKKLGLDNGRIAKITRNQMTFLFAIPITVALIHTLISSNIVYTLLNMIG
                     INNYHIFLTSYVLAVIIISFLYMAMYKITSYIYAKVIHQERN"
     gene            complement(29597..30352)
                     /locus_tag="RPH49_001149"
     CDS             complement(29597..30352)
                     /locus_tag="RPH49_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124315.1"
                     /translation="MLLEVKHVKKVYGKGLNATTALNQMNLSVGAGEFVAIMGESGSG
                     KSTLLNLIASFDGLTEGDIIVDGAHLNNMKNKSKALYRQQMVGFVFQDFNLLPTMTNK
                     ENIMMPLILAGAKRKDIEQRVHQLTVQLHLEGFLNKYPSEISGGQKQRIAIARALVTK
                     PTILLADEPTGALDSKTSKALMMLFQEIHQLEQTILMVTHSNIDASYAERVIFIKDGR
                     LYHEIYRGEESQLAFQQRITDSLALVNGGSVNI"
     gene            complement(30460..31347)
                     /gene="nsaS"
                     /locus_tag="RPH49_001150"
     CDS             complement(30460..31347)
                     /gene="nsaS"
                     /locus_tag="RPH49_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nisin susceptibility-associated two-component
                     system sensor histidine kinase NsaS"
                     /protein_id="HDY5124316.1"
                     /translation="MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILL
                     LLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNEQIEYKNDVESYFLTWVHQMKTP
                     ITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
                     PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFD
                     EQSNQLYVKDNGIGISEADLPKIFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPV
                     SVVSKQNEGTTFTIQFPDE"
     gene            complement(31358..32023)
                     /gene="nsaR"
                     /locus_tag="RPH49_001151"
     CDS             complement(31358..32023)
                     /gene="nsaR"
                     /locus_tag="RPH49_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nisin susceptibility-associated two-component
                     system response regulator NsaR"
                     /protein_id="HDY5124317.1"
                     /translation="MKILIVEDDFVIAESLASELKKWNYGVIVVEQFDDILSIFNQHQ
                     PQLVLLDINLPTLNGFHWCQEIRKTSNVPIIFISSRIDNMDQIMAIQMGGDDFIEKPF
                     NLSLTIAKIQALLRRTYDLSVANDSMTVKGCTLILDEAKVVYQEQNIQLSLTELQILK
                     LLFQNEDKYVSRTALIEKCWESENFIDDNTLAVNMTRLRKKLNTIGVNDFIITKKNVG
                     YKV"
     gene            complement(32049..32249)
                     /locus_tag="RPH49_001152"
     CDS             complement(32049..32249)
                     /locus_tag="RPH49_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124318.1"
                     /translation="MILVMLSPLLIIFFIVLSILEERKRTKKKQLEKEKANTLNQNTN
                     DMESSNQELSLQQAKEQKDNKG"
     gene            32447..33796
                     /locus_tag="RPH49_001153"
     CDS             32447..33796
                     /locus_tag="RPH49_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDY5124319.1"
                     /translation="MLSVKKATKFAVANLIIVSTVFSSITPAIAQSDKSSKDESFAVG
                     NTKNPKNVIFLVGDGMGPSFNTAYRYYKNDPKQNITDSAAGGTAFSSGHKTYNGAIGV
                     DSNKQKVKTVLERAKEKGKSTGLVSTAELTDATPAAYAAHVTSRDDKNEIAKQFYKDK
                     INGKHKVDVLLGGGAKYFGKSNGNLDKKFKKDGYDLATNSKELSKSDKDKVLGLFADK
                     NMPLAIDASKDEPSLADMQQSALSKLERNKKGFFLMVEGASIDKSAHSNDITGVMSEM
                     EGFEKAFDDAIQYAKKHKDTLVVATADHSTGGLTIGKDKGYEWNPQPIKSMKHSGSYM
                     TEKMAKGEDPEKVINEGYGFEFSQDDMKKVKKENKKLQKLLKKNKDEKSADVEKQTKA
                     LQHAIQKPVNDKSYTGWTSDGHTGEDVNTYAYGPRSESFSGNIENTESAKIIFDIFK"
     gene            33866..33976
                     /locus_tag="RPH49_001154"
     CDS             33866..33976
                     /locus_tag="RPH49_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124320.1"
                     /translation="MLGAWLTRSWYFLNAKYKPPTNVKITANFFIIQTPF"
     gene            complement(34079..34534)
                     /locus_tag="RPH49_001155"
     CDS             complement(34079..34534)
                     /locus_tag="RPH49_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDY5124321.1"
                     /translation="MSTNKNDYEHMLFYFAYKTFITTADEIIEKYGMSRQHHRFLFFI
                     NKLPGITIKSLLEILEISKQGSHATLQKLKEQGLIIEKVLETDRRVKKLYSTDKGDQL
                     IAELNKAQDELLQNIYQQVGSDWYDVMEALAKGRLGFDFIKHLKDEKES"
     gene            complement(34780..35541)
                     /locus_tag="RPH49_001156"
     CDS             complement(34780..35541)
                     /locus_tag="RPH49_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDY5124322.1"
                     /translation="MAYISLNYHSPTIGMHQNLTVILPEDQSFFNNDTTAKPLKTLML
                     LHGLSSDETTYMRYTSIERYANEHKLAVIMPNVDHSAYANMAYGHSYYDYILEVYDYV
                     HQIFPLSKKRDDNFIAGHSMGGYGTIKFALTQGDKFAKAVPLSAVFEAQNLMDLEWND
                     FSKEAIVGNLSSVKGTEHDPYYLLDKAVAEDKQIPKLLIMCGKQDFLYQDNLDFIDYL
                     SRKNVPYQFEDGPGDHDYAYWDQAIKRAITWMVND"
     gene            complement(35657..38038)
                     /gene="clfB"
                     /locus_tag="RPH49_001157"
     CDS             complement(35657..38038)
                     /gene="clfB"
                     /locus_tag="RPH49_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin clumping factor ClfB"
                     /protein_id="HDY5124323.1"
                     /translation="MKKRIDYLSNKQNKYSIRRFTVGTTSVIVGATILFGIGNHQAQA
                     SEQSNDTTQSSKNNASADSEKNNMIETPQLNTTANDTSDISANTNSANVDSTAKPMST
                     QTSNTTTTEPASTNETPQPTAIKDQATAAKMQDQTVPQEANSQVDNKTTNDANNIATN
                     SELKNPQTLDLPQSSPQTISNAQGTSKPSVRTRAVRSLAVAEPVVNAADAKGTNVNDK
                     VTASDFKLEKTTFDPNQSGNTFMAANFTVTDKVKSGDYFTAKLPDSLTGNGDVDYSNS
                     NNTMPIADIKSTNGDVVATATYNILTKTYTFVFTDYVNDKENINGQFSLPLFTDRAKA
                     PKSGTYDANINIADEMFNNKITYNYSSPIAGIDKPNGANISSQIIGVDTASGQNTYKQ
                     TVFVNPKQRVLGNTWVYIKGYQDKIEESSGKVSATDTKLRIFEVNDTSKLSDSYYADP
                     NDSNLKEVTNEFKDKITYKYQNVASINFGDITKTYVVLVEGHYDNTGKNLKTQVIQEN
                     IDPATGKDYSIFGWNNENVVRYGGGSADGDSAVNPVDPTPGPPVDPEPSPEPEPEPTP
                     DPEPSPDPEPEPTPDPEPSPDPEPEPTPDPEPSPDPDSDSDSDSDSDSNSDLDSDSGS
                     DSDSDSDSDSDSDSDSDLDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSRVTPPNNEQKAPSNPKGEVN
                     HSNKASKQHKTDDLPETGDKSENTNATLFGAMMALLGSLLLFRKRKQDHKEKA"
BASE COUNT        11888 a         7035 c         5750 g        13470 t
ORIGIN      
        1 aaatggatct atcagtgcca cgtgttactg caacactaat agatcctctt accattaata
       61 tatttctaat taatacttaa aataggctta gtcttctaat aaatatttaa ttgaatcaaa
      121 tgtatcttct aatgttttaa ctgatttgtc gaataatgct tgttcttcag cacttaatgg
      181 catttcataa attttaactg cgccatgttg gttaaccaat gtcggtacac ctaagtaaac
      241 gcctttgtga ccgccatatt gaccatctaa ttgtatagaa acatttaaga cattattttc
      301 attatttaaa atggcttttg aaatgcgcat caatgctaat gcaataccat agtatgttga
      361 ccctttagct tggataattt cataagcagc gtcacgtgta tttacataaa tttcttccgc
      421 tttagcttcg ctaccagttt gttcttttaa tgtgtcatat actgaaatac ctgctacatt
      481 tgcttgtgac caaactgcaa gttcagtatc accatgctca ccaataatac tagcgtcaac
      541 acttgaaggt gcaacaccaa gttcttggct aattaaatat tgtaaacgtg cactgtccaa
      601 tacagtacct gaaccgataa cacgctctgc tggcaatcca gtatattctt ttacaaatct
      661 tgttaaaatg tctacagggt ttgccgcgat taagaaatat ccatcaaagc cgctatccat
      721 tacactctta acaatgctct tcataatctt agtatttttt tcaactaatt gtaaacgtgt
      781 ttcacctggc ttttgaggtg caccagctgt aataacaact aaatctgcat ctttacagtc
      841 ttcgtattca cctgctttca catcaactgg tgaaggactg tggactgtac catggtttaa
      901 atcttgaaca tctgctttta ctttgtcttt tgcaatgtca ataattacaa attcatcagc
      961 aacaccttgc gtaaccattg caaaggcata gcttgatcct acagatccat ctccgattaa
     1021 tacaaccttt ttaccaaatg ttttcataat tatgtctcct aacctaattg aatttatttt
     1081 acacgtgact acacgtaaaa atatctatac tgaaattaaa gattaacaat tttattttat
     1141 tataatatta tgctaccaaa ttacaaacat aaaactgaga tgtaagcgga gtcaaattac
     1201 actctatcgc caataaatat tgatatctca agctttagca cgtaatttga aatttgtgac
     1261 aatttttagc attctaaaat tgcataatga cgctatttaa aggctttaac aaactattga
     1321 gctttctatt tttttcaatt taaaaaggat ggctattcga cttaaatgac ttactatata
     1381 acctcctatt ttccgcctta ccctcatcat atttgatgca tctttttata gtcaaagaat
     1441 tacatttcat acacactaac caatcagaca taaacatgaa attgatttta aaaatataat
     1501 gtgcaaaatt gttagaaaat tagcaaaaaa tagtacttat tcatttaata tctgttataa
     1561 tcagttttat catttaaaaa atctacggat gttatcaaga caagtcatta atacgtaaca
     1621 taaagttgtg atttttcaga atttttagac aaaatattga ttatttgtgc tatgatataa
     1681 catattaaaa aacaccgtat agaattgttt atgaatgttt gggaggaaag tttatgggaa
     1741 gttttttcaa taaaatagca cgaaaagagg atccggctat ctatcaaaat aaagatggtc
     1801 atttaaagcg tacacttcgg gtgcgtgatt tcttagcttt aggtgttgga acaattgtat
     1861 cgacatctat ctttacgcta cctggcattg ttgctgcaca gcatgcaggg ccggcagttg
     1921 cgttatcatt cttactcgca gctattgttg ctggtttagt tgcatttact tatgcagaaa
     1981 tggctgccgc tatgccattt gcaggttcag cctattcttg ggtcaatgta ttatttggtg
     2041 aattctttgg atgggttgcc ggttgggctc tattagctga atattttatc gccgtagcct
     2101 ttgttgcatc aggattctca gcgaatttac gcggacttgt gaaaccaatt ggcatcgaat
     2161 taccagcagc attatcaaat ccatttggta cgaatggcgg ttttatcgat attattgctg
     2221 ctatcgttat tttattaact gcattattac tatcacgtgg tatgtcagaa gcagcacgta
     2281 tggaaaatat tttagttatt ttaaaagtat tagctattat tttatttgtc atcgtaggtt
     2341 taacagcaat aaatgttagt aactatgtgc catttattcc agaacacaaa gtaactgcta
     2401 caggtgactt tggtggttgg caaggcatat atgctggtgt ttcaatgatt ttcttagcgt
     2461 atatcggttt cgattctatc gcagcaaact cagcagaagc acttgaccct caaaagacaa
     2521 tgcctagagg tattcttggt tctttaagtg ttgctatcgt attatttatt gctgtagcac
     2581 ttgtgttagt tggtatgttc cattactcac aatacgcaaa caatgctgaa cctgttggtt
     2641 gggctttacg tcaaagtggt catggtgttg tagcagctat tgttcaagct atctctgtaa
     2701 tcggtatgtt tacagcatta attggtatga tgttagcagg ctcacgttta ctttattcat
     2761 ttggacgtga cggcttatta ccttcatggt taagccattt aaacgacaaa catttaccta
     2821 atcgcgcact agttatactt actattattg gtgttttaat tggttctatg ttcccattcg
     2881 catttttagc acaattaatt tcagcaggta cacttgttgc atttatgttc gtttcattag
     2941 caatgtatcg tttgagaaag cgtgaaggta aagatctacc aattcctgca tttaaattac
     3001 ctttatatcc tgtgttacca gcagttacat ttgttttagt attgctagta ttctggggat
     3061 taggattcga agcgaaatta tacactttaa tttggtttat tgttggtatc attctatatt
     3121 taagttatgg acttagacat tctaagaaaa atgacgtagc tgaataccac ccaccaaaat
     3181 aaaaatcaaa aaaatcattt cccatctgat taacatccag atgtggaaat gattttttat
     3241 tttatattaa gataatcgct attaccaacc ttgtccagat atgtcatatt gatctaagtt
     3301 acctgcttcc aaagcagtca gtgcatcttc tatagtgttt aacgccgtgt ctaattgctc
     3361 atatgttatt accaatggcg gttggaatcg caacacattt cctgctacag ctataataac
     3421 tacgccatgc tcaaagcagt aattacaaat tttaagtgcc gcactggcat cacgtgtttt
     3481 gagttttttg tcggaaacaa tatcaatacc aatgctcaga cctttacctc taacatcgcc
     3541 tacactattg tatttagata cccattgatc cattcgtttc ctaacatatt cccctttttc
     3601 cgcactagcc tgaagaagcg actgatcttc aatcatttga attgtggcta atgcagcttc
     3661 acaactaact ggattagcac ctgttgtaaa taaatgtgct ggcgcttcta aacaattcat
     3721 aatctctttg cgtccaacaa ttgctgacat aggcatacca cctgctaagg attttccaaa
     3781 agtgattaaa tcgggcgtaa aattaaaatg cgagactgaa ctccatgtac ctgttctccc
     3841 aaaaccttgt tgaatatcat cgacagcgat taaaatacca tgttcacgac aaatcttttc
     3901 taacgtttca aaataccctg gaactggttc taaaagtcca ccatcgcctt gtatcgtttc
     3961 aataacaata catgctactt catcagcagg tacatatttc gcaaacattt cttttaaggg
     4021 tgctaaatat tcttctactg aattagcttg tggctgctcg tacataccac gatatttatc
     4081 tggaaacgga atatgataaa aaccattcaa taacggacca taatgtttgc gcatatttaa
     4141 actaatagct gacatagaca atgagccaaa agttgaacca tgatatgcat tagtgaaact
     4201 aatgatataa ggacgccctg tatatgctct ggcaaattta atgatgccat catttgcgtc
     4261 tgatccggtt aatccgaagg tcactctttt ttcaaaatct ccaggtgcaa tctgacaaag
     4321 cttcttagct aaacgtacca acggttcatg atacatatat gctggtgtat aatgaataaa
     4381 tttatcaact tgtgccttta tcgcttctgt tacttctcta ggtgcatgac ctacgttttg
     4441 agaactcgca ctcgataaca aatcgatata tgtcttcccc tcaatatcaa ccaatgttgc
     4501 tccatatcca tgatcaatca ctaacggata atatttaata cgtcctgatt tcgcaaaata
     4561 atgttcatcc tcttgaatta attgatgtgc tttactcata tacattcccc tcccattgac
     4621 agtattaatg tgcaagcaaa gtggcctctc ttaaatcgat tataaaatcc gatttaaaat
     4681 cctgctcaaa taccgtcatg cctctatgaa tactatccaa tatactaata aaattcagat
     4741 ttgtaaatat attctgataa ttaagaattt tatatcaatc tactttgttt atgcgcataa
     4801 ttttgttcga ttagggaatt gtttactata tttcatttga ctctgaggtg atacgaatgc
     4861 gtttaaaagt attgttccat ttcattgctg ctattttcat atcattcatg ttgctatgga
     4921 tgaccatgtt gtttgactta ataagcaatc aatcacattt aaaagcttta ttattgaatt
     4981 tagattttct aattccttct gacaatacac catatattct agaaataata tgtcacttac
     5041 taattggtag cgtcatttat tttatatttg tgttgctgtt tcatacttct aaaaggcttt
     5101 actatctatg ttatatccct ttatttttct tatttatagc attgtatccc tttttagtat
     5161 ttattgcgca acgtccaatt tttcaattta gtgtgacaga attaatcggt tggattatta
     5221 cacatatttt ctttatgtca ttaatagcgt tagtcatacc tagaataaaa taatattttt
     5281 aattaaactg acaattattt ttcacatttt atacactttt caaggtttat gacttgagaa
     5341 atgttctcat ttttatcata ctggaggtgt attgaaaagt taaggagtgg aaagtatgaa
     5401 taaagagcaa ttagaaaaaa tgaaaaatgg aaaaggcttt attgccgcat tagaccaaag
     5461 tggtggtagt acaccaaaag cacttaaaga atatggtgta aacgaagatc aatatagcaa
     5521 tgaagacgaa atgttccaac ttgttcacga tatgcgtaca cgtgtggtaa cttcaccttc
     5581 attctcacca gataaaattt tgggtgctat tcttttcgaa caaacaatgg atcgcgaagt
     5641 agaaggcaaa tacactgcag attacttagc tgataaaggt gttgttccgt tcttaaaagt
     5701 agacaaaggt cttgctgaag agcaaaatgg tgttcaatta atgaaaccaa tcgacaactt
     5761 agacagttta ttagaccgtg caaacgaacg tcacattttt ggtacaaaaa tgcgttctaa
     5821 cattttagaa ttaaatgagc aaggtatcaa agacgttgtt gaacaacaat ttgaagttgc
     5881 taaacaaatt attgctaaag gtttagttcc aattatcgaa ccagaagtta atattaatgc
     5941 aaaagacaaa gctgaaattg aaaaagtatt aaaagctgaa cttaaaaaag gtttagatag
     6001 cttaaatgct gatcaattag taatgttgaa attaacaatt cctactgaac caaacttata
     6061 caaagagtta gctgaacatc ctaatgttgt tcgtgtcgtt gtattatcag gtggttacag
     6121 cagagaaaaa gcaaatgaat tacttaaaga taacgctgaa cttatcgcaa gtttctcacg
     6181 tgcattagct agtgatttaa gagctgatca atctaaagaa gaattcgata aagctttagg
     6241 tgatgctgta gaatcaatct acgacgcatc tgtaaacaaa aactaattta tacattaaac
     6301 tattttttga tataaactac taaaatggac tcatacatgt gctttaaggg cattgtgtat
     6361 gagtcttttt tgattaaagt tgattttgcc gtatgtatta gattacgtaa aaaatcggac
     6421 agctgaaaaa tctataagat ttctcagttg cccgatttta aatatagcta ttagaattta
     6481 gttttcgtag taacctaatt ctaagtcttt tgaagtttgt ttacggattt ttctcattaa
     6541 tttttcgtct tcaattaatg attcaccgta tgatggaatc attttcttga ttttaggtgc
     6601 ccattcagtt ttgtattcag ggaagttacg ttctaatact tctaacgcaa ctgaaactga
     6661 agttgaagcc cctggtgatt cacctaataa tgcgattaca gtatggtctt gtgagttaac
     6721 cacttctgta ccgaattgga tgaatccttt accgtgttca ggtgtatctt tgataacttg
     6781 tacacgttta ccagcagtgt ataattgcca atcttcatta cgtgcttctg gatagaaagt
     6841 acgtaagtgg ttcatacaac cttcttttgt cataatcact tggtcaaatg agtatttaat
     6901 taaaggtaag tttttaactg ctgctgctaa taaagttgta atgttgtatg ttttaactga
     6961 tttgaataaa tctaagttag aaccattttt caagaattta ggtccaacat tagcaaatgg
     7021 tccaaataat aatgttcttt gaccatcaat gtaacgcgta tctaaatgag gtactgtcat
     7081 tggtggtgta ccaggtggct ctttaccata aactttggca tcgtgttgtt caataacttg
     7141 tgggtttgta caagctaaga attgaccact gatagggaat ccacctaaat gcttactttc
     7201 agggatacct gttttttgta ataatggaat tgctccaccg ccagcaccga tgaatacata
     7261 gtcagttact tgtttgaatt tctcaccagt taggcgattt ttaacagtaa cttcccattg
     7321 accatttgat aattgttcaa aatcaacaac ttcatggtta aattgcactg tagcatttgg
     7381 atgtgcttca atgcttttag ccattttacg tgttaattca ccgaagttta catctgtacc
     7441 ttcgtcaatt ttacttgccg ccatgatacc agggttatct tcacggcctt tcatcatcaa
     7501 tggaatccat tttttcatta cttcgatgtc ttcagtatat tcgatattat cgaacatagg
     7561 gaaagctttc atcgcttcgt aacgatcttt taagaattta acattgtttt tacctctaac
     7621 ataactgatg tgtggtaatg gattgataaa ttctcttgga ttctcgatgc taccgctttt
     7681 cactaagtga ccccagaatt gttttgaaat ctcaaactct tcgttaatca ctttcgcttt
     7741 ttcgatgtcg atagaaccat caggttgtaa aactgtgtag ttcaactcac ataatgctgc
     7801 atgacccgta ccagcattat ttctttcgtt tgaactttcg attgcaggac gatccaagcg
     7861 ttcgtaaacg tggatattcc agtctggctc aatttctttt aacattgaac caaatgttgt
     7921 gctaagtaca ccggctccaa ttaaaacgat gtctttacta ttagacttag ccattggttt
     7981 cacctctcca aaaattgtaa atgtgtatca tcaatatgaa agttacataa aactgacata
     8041 tttctttaaa atatcaacgc catagataac ttcctgtttt aattgatacg ctgtaacaaa
     8101 atactatagt tagtgcttac atgtatatgt taaagcaagc agtggtaaat gtaaattata
     8161 attattcatt aactttgcaa tatattaaat cttttattca tagaagataa atatcaaatc
     8221 aatcataatt atttgacaac aaatagctaa cgattgtttt aatctacatc tggcttatag
     8281 cattttaaac ctatactcta ttttgataca atataagtgt aaaatcaatc ataaaaagga
     8341 gattcaatac acatgcatcc aagaaaacca cttcaattac ctttaatatt gaaaattatt
     8401 ttgaatcttg cacttatagg tattgtaatt attattttaa cacacactga gtttcaactt
     8461 aatgccggtg atagtaatgt atttttatta aattgggata ttcgaggttt aacatcttat
     8521 attttctcat tcttaatact ggttgcgctt gtttctaaac taattttatt atttataact
     8581 agacgacaaa gaacatcata aataaacaag cagtccagtg cgtatcatca taccttacgc
     8641 attggactgc tttgctatgt ttattgattg ctatcttttt gttgttgcca tttttctatt
     8701 tcagcatctc gtagttcaac acgacgaatt ttacctgagt ttgtttttgg taagtcgtca
     8761 acgaattcaa tctctctcgg atatttatat ggtgcaactt catttttaac aaattgttgt
     8821 agttctttaa ctaacgtatc atcacccgca gtatggtctt gtaaaataac gaatgctttc
     8881 acaatattgc ctcgtatatc atgaggtttt gctactacag cacattcttt aacggctgga
     8941 tgattcgtta acgcatcttc aacttcaaaa ggcccaatcg tatagcctga actaataata
     9001 atgtcatctc gacgtccttc aaaccagaaa taaccatcat catctacatg agctaagtca
     9061 ccagtgatgt agtatttacc tgtttgcgct ttcgccgtac gttctggctc cttataatat
     9121 cctttgaaaa gtgctggcaa atcaagtggt actgcaatat tcccttccgt attagcaggt
     9181 acgctattcc cctcatcatc tactacagtg accgaactac ccggaatgcc tttacccatt
     9241 gatccaatcc tttgtggtgt atcttttaaa aagcctataa gcaaggtact ttcagtctgg
     9301 ccatatccat ctcttacagt taaattaaag tatttcttga attgttcaac tacttctcga
     9361 tttagtggct cacctgcaga aacggcacta tgtaaatgcg ttaagtcata atcatttaag
     9421 ttctgtaatt tagccatcat acgatattct gtcggtgtac aacataaaac attaatttga
     9481 tatttttgaa gcaattctaa gtatgtttca ggactgaatc ttccattaaa tacaaaagca
     9541 gttgcacctg aacctaatac agataagaaa ggactccata cccatttttg ccaacctggt
     9601 gctgctgttg cccaaactaa gtcatcttca ttaatacata accaatgttt tggtgccatt
     9661 tgtaaatgtg caaatcccca tccatgacaa tgtgtaacgg ctttaggatt gccagttgta
     9721 ccagatgtat atgacaaaat cgctgtatca tctcgcgtcg tatctgccat ttctagtttg
     9781 ttacttgcgt tttctttttc agcttcaagt gaaatccatc catctttttg accggcaata
     9841 acaaatttag ttaacgcatc atatccttta attttttcaa attcaactgt gaatggctct
     9901 agtgcaataa ctgcattaat ttcaccatgt gtgatacggt attgtaaatc tttagttctt
     9961 agcatttcag aacatggaat gattgcgaca cctaatttta aagcagcaat atataattca
    10021 tacgtcgcaa tagatcgtgg catcataatg agtactttat cacctttaga taaaccgtgc
    10081 gatgctaaaa cattgcctac tttattagac tgttcaatga gctgttggta agtgactgat
    10141 atatcttcgc cttcagtatt atgatataaa attgcctttt tatctggtat gtggctatat
    10201 ttttcgattt ccgaaataat gttatatttt tcaggcgcga atagagctga cttttgcata
    10261 actaacttcc tttcatacat ccacttttcc tgtgatgaac attgtaattt tataaatgaa
    10321 ttatatatat catacgccta tctttacaga attttcaatt aaatagggtt aaataccaaa
    10381 gtcctcgaca ctacactttg ccatgacgta gcattcaagg actttcaaat gattgagggt
    10441 tgatatctcg ggctagacca tatcagctaa ttcaatacga atattgtatg ataattcacg
    10501 attaattatt tttacatctg cacctttcga agtgccacga tgcttgtgtg tatgcttgta
    10561 ctcagctgaa ttttgccaat gataaaatgc tttcctattt tcccacagcg taataatgat
    10621 atagtgtcta ccagctgttc taggtcttaa aaaccttaat gctttaaacc catcaacgtt
    10681 ttttaaatgc ttattacgtc gcaaaaattt ttgctcgaat gtttcttctt gtccttcgtt
    10741 aatatataaa tgatttaaca cacataatga atcatttgat aaatcattta tcgcttctag
    10801 cacatcgtaa tatgcagtgt cattattttt ttgtattgtg agacaatcat ccagttcttc
    10861 tattacataa cttctatatt catcataaat gttcataata aatgccttca tttcatttat
    10921 atttttggtc atattacttt atatctatta ctaattcatt cccgtattta ttaattacaa
    10981 tcatagtttg gcttcttttt aaaagatacg actttgtaaa aagtattaat atttcataca
    11041 aatgggtaca ggaatcgcac actatttttg tgtcttcaat ttcatgatca ttatttaaca
    11101 ctagtcatga aaatagccga caacttcatc tgtgaaatta ccggcttttt attttagcta
    11161 actttatttc tgattttacg attttaattg atcatacaga gaaagtgatc tttttacaat
    11221 ttctaaaaac tcatgatcta tattggacat ttgatgaaaa taagacaaaa tgttttctgt
    11281 tagcttctct tgttttggga atgaatcatc ttctttaatc caaatcgcta attcgcctaa
    11341 tggtgtttta tcatctttaa atgtttgtat atattcgtaa aagctcatag tattccttct
    11401 ctcaatttac ttatataaat cctaccacga aagctttcaa gaaaacacaa ttaaatgtct
    11461 atttagtgaa ctttttaaag ttctacactc ttttaatgtc tgccaattag gtcaattaat
    11521 catcacaatg taaaattaac tctattttca gttcatatac tcacacatcg tttttgaaca
    11581 acacattaac ttctcattta gataaaacgc aaaaagcctg gcaccaatac aatagatgcc
    11641 agactaagag tctactatat acatttattt agcgtatggt tttacttcga ttgcaccttc
    11701 attttcatca tgaacaccat gcttataata atcaatatat tgtggctcta aaggctttct
    11761 gccacgtata atatctgctg ctttttcagc taacattaaa acaggtgcgt gtatattgcc
    11821 atttgtcgta cgtggcatag ctgatgcatc aactacacgt aaattttcca taccgtggac
    11881 tttcattgtt aacgggtcaa ctactgccat tggatctgaa gcaggaccca ttttagcact
    11941 acaagatggg tgtaatgctg tttcaccatc tctacgaacc caatcaagaa tttcttcgtc
    12001 tgtttgcact tctggtcctg gtgaaatttc tccaccattg aatggatcca ttgctttttg
    12061 agataaaata tttcttgcta cacgaattgc ttctacccat tcttttttat cttcttctgt
    12121 tgataaataa ttaaagcgga tacttggttt ttcgaatgga tctttagatt tgattttcaa
    12181 gctaccacga gagtttgaat acattggtcc tacatgaact tgataaccat gtgcgaccgc
    12241 tgccttttga ccatcatatc ttacagctat tggtaagaaa tggaacatta agttaggata
    12301 atcaacttcg ttatttgaac gtacaaatcc gccaccttca aaatggttag atgctgctgc
    12361 acctttacgt gtgaaaatcc attgtaaacc aataaatggc atgcgcttga tatctaagct
    12421 tggctgtaat gatacaggtt ccttacattt atgttgaatg tatacctcta agtgatcttc
    12481 aaagttttca cccacaccag gtaaatgaac acgtggctca atgccttttg attttaggaa
    12541 ctctgaatca ccgataccag ataattgtag taattgtggc gtattgaatg ccccaccaga
    12601 caaaatgact tcattagcat cgatggtatg tagtttgcca tttttcttat acgtaacacc
    12661 agttgctctt ctaccttcat aatgaatttc agttacaaag gcacgtgttt caacggttaa
    12721 gtttttacgc ttcatcgctg gatgtaaata tgctcttgaa gctgacattc ggcgaccacg
    12781 atgtacttga ctatcgaacg gtccaaaacc ttcttgtcta aatccattca catcaggtgt
    12841 tttatgatag cctgcttcaa cacctgcatc aaagaatgac tggaataaag gattcgttgc
    12901 tggccctcgt tttaacttaa ttggtccatc atggcctcta aatttatcat aaggcgctgc
    12961 accgtatgtt ttttctaatt ttttaaaata cggtaaacag tgcgcaaaat cccaagtttc
    13021 cataccttct ggttctgccc agccttcata gtccattgga ttaccacgtt ggtaaatcat
    13081 gccattaatc gaacttgatc cacctaaaac tttacctcgg gcatgtgcta ctttacgacc
    13141 gcccatatgt ggttcttcat ctgttgaata aatccaatcg taaaatttat tgcctgaagg
    13201 gaacattaac gcagcaggca tttggataaa taaatcccaa aaataatcac tgcgacccgc
    13261 ttctaatact aagacttctt tatctttatc ttcactcaga cgattaccta gtacagaacc
    13321 tgcactgcct cctccaatga tgacataatc atatgatttg tttttgttac tcatcgttat
    13381 gacctccaaa gtttgttgta tttcaaagtg agtattgcat gaaatatttg ttagtggctg
    13441 attggttatc gttgaattgc taaacttagc taaccaaaac actcgctttt ccttttacga
    13501 ttgttactaa cagtcatgaa ataatctatg attcattttg cgtttagtcc aaattatcaa
    13561 tcaacatttc gccacttata caaaacaaag tgagtgtctt gtgttcttac aatggcactc
    13621 accttatcta atttttattt gctaaaccaa ttcactaatt gtggatttgt atttgttaaa
    13681 atgtgttttg aaacaaggta ctcttctaag ccttctttgc ctaattctct accgatacct
    13741 gattgtttgt atccacccca tggcgcttgt gcaaaatatg gatggaaatc attaatccac
    13801 accgttccaa gtttcaactt gttagcaacg cgttgtgctt ttccaatatc tctagaaaat
    13861 acagcacctg ctaaaccata tatagaatca ttcgctaatt gaatcgcttc ttgttcagtt
    13921 tcaaagcctt ctacagtaac gacaggtccg aaaacctctt cttgtacaat acgcattgac
    13981 gtatcacaat ttgtaatgac tgttggctcg aagaatagac catcttttaa atcatctcta
    14041 tctggacgtt taccaccaac agcaattgtt gcgccttctg ctttagctac atccatataa
    14101 gattcgatct tattacgatg ttctgttgaa atcactggtc ccatttcagt atcagcatca
    14161 aaaccattac ctaatttaat ttttttcacg cgatcaataa gtgcttgctc aaatttgtct
    14221 ttaatactgt tttgtactaa tattcttgat cctgctgaac aaacttgacc tgcatggaaa
    14281 tatccaccat ttaacgcttg gtctaccgcc aattcaaaat cagcatcatc aaagataatg
    14341 tttggatttt taccgccaag ttccaaggca atattcgtaa cattattagc agcatttttc
    14401 ataatatgct taccagtctc aatgccacct gtaaatgata caaggtcaac ctctttatga
    14461 cctgacatta cgtcaccaac ttcagaacct gcacctagaa taagattaat tgttccttta
    14521 gggaaaccaa cttcttccat taattcaaaa acacgtattg ttgttaatgg tgtaatttca
    14581 cttggtttca taactagtga acaacccgta gcaagcgcag gcgcaatttt ccatgatgct
    14641 tgtaataacg gataattcca aggtgtaatt tgtgtaacta cacctactgg ttctttaaca
    14701 attttgcttt ctgtatctgg aattggtgaa tcaatcattt cgccaccgtc tttatctgct
    14761 aatccagcaa aatacataaa cacattatga atatcatcca tatctgcata tgattcttct
    14821 aacgtttttc cagtatctaa tgtttctaat cgtgctaacg cttcgcgatg ttctttaatc
    14881 ttgtccgcga tggcacgtac ttttttacct cttgtttcag cagtttcttg cgaccattca
    14941 ccagactcaa acgcacgtct tgcagctaag attgcacgtt ctgcatcctc ttttgtccct
    15001 tcagaaaccg taaatatcac ttcttgattg taaggattga taatatctct tgtattttta
    15061 ttcgcgcttt caacccactc accatcaata tattgacgct gagataaatg ttttaaaagt
    15121 tccattcaac aacctccgtt aagtttgtta aatttttatt taacgaattt tacaaactta
    15181 tgttagcata gaaatgaaaa atgtgtcaat ttacaaaaca actaaagaat taagttttgt
    15241 aagttcgtta gatttttatt taacgaaaca tttaacttta atgctttaaa tatttttaat
    15301 gtcttttttt agaaaaggtt ttataatgta ttagtattta ttttaacgtg accaaaatga
    15361 tgtacggagg tgcaatgatg actcgttctc agaacaaaca gcaacaatta gaacaagcaa
    15421 aagatattgt aattaattca attggacaga caatggattt gtatggcact aatagaagtg
    15481 taggaaactt atatggcact atggtgtttg aaggcagtat gacgcttgat gaaatgcgtc
    15541 atcaattgca aatgagcaaa ccaagtatga gtgctggcgt taagaaattg caggaatttg
    15601 atattgttaa acaacaattt acgagaggaa gccgcaaaca acattttatc gccgagaaag
    15661 actttttcat ctttttccga aactttttca ctaaaaaatt ccagcgtgaa attgatatca
    15721 atgtcgaagc agtaaaagat gctcaagcta ttatcaatcc attacttgaa agcagtgatt
    15781 taactgaagc tgaaacacaa gaggcacaaa aaattaaagc tcagcttgat catacacatg
    15841 tttattacga atggttagaa cagttaaccg aagcgattga aagcggtgaa attttcaaat
    15901 atttcccaat tccagaacaa ccttctgatt ctgaaaatta aaattgactc aaacaacgac
    15961 aatgatgatt atgcatgatg aaaacaatgc aacaggtcca cgaaataaac ggtaatttct
    16021 atctcaataa atagaaatta ccgtttttgt tttatatgac aatcaattat ttacttttaa
    16081 aaatcaaagt cttatgtgct atttatttaa ttataaatta tcgtcttgtt cttcttctga
    16141 tacttgaacg attcgcaatg aacgacgttc aacttctttt aatttttcag cacgcgtttc
    16201 aagtttaatt ctatcgcgcc ctaaaatgat taaaaatgat atcatcatga aaataaaaat
    16261 aacaattaat ggcacacttg ccagtattga agcagttttc aatacttcta atgcacgttc
    16321 gccaccaact agcatcaatg aaaatggcaa taagcacaat gcaaatgccc agaataaacg
    16381 attggcacgt aatggttcgc ctaccacttt tttctgagat gctgccgcta aaatatatga
    16441 acccgaatca aatgttgttg ctaagaataa gaaagcagat actaagaata gtacaatcat
    16501 caatgatggg aatggtaaat gatgcaccac ttcaataatg gttgcctctg taccatgtgt
    16561 atttaaatat tgtgttacat taaactgtcc agaaatttgt aaatacacag catagttacc
    16621 aaaaatacca aagaataata cgcatccaag cgttccataa ataattgttc ctagcacgac
    16681 ttctttaagg cgtcgacctt ttgaaattct agcgataaat aaaccgataa atggcgcata
    16741 tactaaccac catgaccagt agaatattgt ccagtcttgt gggaaattcg tttcttttcg
    16801 acctttaata ccaccgaatg gttctaacca tgttgccata tggaaaaaat ctctcaacat
    16861 atttccgaac cctgtcactg tcgtttccat aataaaaaca gtcggtccaa taataaatat
    16921 aaaggctaaa agtacaaatg atagccaaac gttgatatca cttaactttt gaataccttt
    16981 tttcaatcct gtatatgaac taatggcaaa tataaccgtg attgttaata aaatggccga
    17041 acgtaaaatc atatttttac catctaaacc agttaatctt tctatgcctg cagaaattaa
    17101 tggcacacct aacgctagtg atgttgccgc accacctagc aatccaaaga taaataagat
    17161 atctacaact ttacctacaa atttatctgt ttgacctttt aaaatcggac gacaagcttg
    17221 actaatttta tacaccggtt gttttttaac aaatactaaa taaccaattg gtaatgctgg
    17281 tagaacataa atagcccaag caattggccc ccagtggaac ataccatatt gcgtcgcata
    17341 ttggagtgct tcatcactca tacttttcgc gccatttggt ggaacttgat agtaaaaagc
    17401 ccattcaata acgccccagt ataaaatatc agagcctatg cctgcacaaa acagcattgc
    17461 agcccatgta aatgtattaa attctggttt atcacttgct ttaccaagtg tgacattacc
    17521 atatttacca aatgcgatat acattacaaa gcaaaaaatc gccagcccca taaataaata
    17581 tatcgaacca attgaatcag aaatggcact attaatacca gtgatgatat cttcacttgc
    17641 ttttggaaaa gccatcatag gtataactgc aaaaagaagt acagctactg tccctataaa
    17701 ggtcgtccag tccataactt tctctttttt caattgtgct ccccctaatt attaatttta
    17761 tgaatcctgt ttcgatttat ctcaaaatgt aataattata ttgattcaca aaattgacaa
    17821 taactaacat ttaataataa tgcaaatttc atacaatttg aaacttggca attattgaat
    17881 atttatataa tttttcccgt aataaacaaa accttaatag cgctaaaaca acagtgttaa
    17941 gttacgattt aacgaattta acaaatttta ctagaatggc atttaagaat atttatacgt
    18001 tattaacgaa tatttattta ttgtaaaacg ctaccaaaaa gttagacttc cttcccacta
    18061 aaataccact tttttctttc aactttttta aaaaacggat atgcaacttt tagtattggt
    18121 atcaaaatga ttgttaggtc atattctatc aatatatttt tctaaaaaat tgcttttatt
    18181 aactttcaat tatgtaccta acctaaaaag aagccaaggc aacgcatgtt accttgactt
    18241 ctaatacata ttcaactaac aatatattca atcatacgcg catgcgagag tgattgttgt
    18301 acatctataa tacgttgatt taaagaacct ttatatggta aatcaggttt gaataagtgt
    18361 tgtataaata gcccatctac taaaacgtca atgtatgata ataactctcg acgttctgca
    18421 caatcatttg ctaaatattc atataaaaat ccagtccata cccaaattgt ctttgtattt
    18481 ccaaaacgtg ctcgaaatgc tttgacaaga tttaatgtaa tatccaaatt acaaaatggt
    18541 tcgccaccta atagacttag cccagatata taatcatgat cgcagtcatc taatatttct
    18601 gctaatattt catcagtgta tttctcgcca tatctgaact tttgtgaggc tttgttgtaa
    18661 catccaacac aattaaatgg acatcctgat acataaacac tgcatcttac tccttcaccg
    18721 tcaacaaagc tatttgattc tattttagca atataacctt gtccttgttt aatgtctaaa
    18781 agtgtcattc tttaggcgct ttcatatgtt ttactcgtgc gcaaatttct ttatgacggc
    18841 ctttaattac tggacgttga actggattgc ctaagtaacc acatgttcgt ttaacgacat
    18901 caactgtttt aggattatca ttgccacagt tcgggcattt aaatcctttt tcagttgctt
    18961 caaaatctcc atcgtaatca cattcataac aatgatcaat cggaatattt gtacctaagt
    19021 aaccaacttt gtcataagag tagtcccata ccgcttctag tgctttcaaa ttgtgttgca
    19081 atttcggata ctcacaatag tgaatgaaac caccactcgc ataataagga taatcttttt
    19141 caaaatctaa cttttcaaaa ggtgtaacat ctttacgtac atcataatgg aaagagtttt
    19201 ggtaatatcc tttatctgta atgtctttaa tatctccaaa tctctcttgg tctaaacgac
    19261 aaaaacgatc cgttagcgat tcactcggcg tactgtaaat actgaaccaa atgtcatata
    19321 attctgtcca tttcgtttga taacgtttca tttctttaag aatttcaagc gtaaatgctt
    19381 ttgcttcttg agatgtttcc cagtctggac catagaaaac agtagctgtt tcatacaacc
    19441 ctatatagcc cattgaaatc gttgcacgtt tatttttaaa taactcagca acatcatctg
    19501 tttcttttaa tttatagtta aatgcgccac ttttatataa aatcggtgcg ttattcggta
    19561 cagcatcttt caaacgattt atacgataaa gtaatgcatc atgtaacaca tcgatacgtt
    19621 cataaaagat ttcccagaat tttgtcatat taccagcaga ttctaatgcc attctaggta
    19681 aattaagcgt tacaacacca aggttacaac gaccattatt ttcaaaatga ccttccgcat
    19741 ctttccaact tggtaaaaat gaacgacaac ccattggcgc tttgaaatca cctaatattt
    19801 ctacgagttt gtcataattt aaaatatctg gatacatacg ttttgttgaa cactttaatg
    19861 ctagttgttt aatgtcatag ttcggatctt gcggactaaa gttggttcct tttttaattg
    19921 aaaatacaag ttttgggaaa atcgctgtcg tgcggtcttt tcctaagcct ttgatacgag
    19981 tatttaagat agcttgttga attttgcgac ttaaatgatc tgtacctaag ccgaatccta
    20041 atgttacaaa aggtgtctgt ccattagatg tatataaggt attaatttca tattctaaac
    20101 tttcaatcgc atcattgatg tctttagtga cttgttgatc aacataacgg tcgatttcag
    20161 attctttgac aaattgcttt gcgatattcc tatgttgttc ttcattatgt cgtgcatatg
    20221 tactaagtaa ttcgtcaacg cggtcaaccg tacagccacc atattgactg ctagaaacat
    20281 tggctataat ttgtacaagc tgcgctgatg cagtttgtat tgattttggt gaagttacat
    20341 tcgcgttgcc tatttcaaat ccattatgta gcatattttt agcatctatt aaacaacagt
    20401 ttgttaacgg ttggaatgga tgataatcta agtcgtgaaa atgtatgtcc cctctttgat
    20461 gtgcatctgc aacgtgcttt ggtaataaat gatttaatgc gtaagattta gaaacgatac
    20521 ctgctgttaa atctctcatt gttgaaaatg tatcactatc tttgttggca ttttcgttaa
    20581 caatagcagg atctttagaa atcaaacccg ttaatgcttc ttcgatttga ttcattttac
    20641 cccttcttcc tatatattgt gtctactcat tacgttatac cactatatat agtattttca
    20701 aatttttatt agtctgttaa ctaaaacgtc acaaagttat taacatttag tgaaattcat
    20761 atttctacac aattatttca ttaattttta aaattgttct cgaatcgttc cgtctttcta
    20821 gcatagttac ataccatcat ttcattttgc aacgtgacca tagtttctat tttttcatac
    20881 ttaaatcgtc acaatgccca tcaacatcgc aattactaac atcacgatgg cgaatcccca
    20941 aatccaaaag aatgcatact taatatacgt gcccatgttt gcctctgcta aaccaattgc
    21001 caaccataag gctggtgaaa acgggctgac aaatgtacct ataatattcc ctatgaccat
    21061 tgaataagct gttgatacag acggtacacc aaattgccct gctgtttgtt cgacgattgg
    21121 taacacagca aaataataag cgtctgtgct agttagtaaa tctaatggta caccaagtaa
    21181 acctacaata atatgcaagt atggccctac ttctgcagga atcactttga ttaaattcgt
    21241 cgcaatcgct ttaagcatac cggtttcatt tagtacacct aaaaacatac ctgctgcaat
    21301 aatcactgca gccatcatta atgcattcgg cgcatgcgct cttaatcgct ccatttgttc
    21361 atccactgat ttaaaattaa taataagtgc caatgaaaca cctatcatga atgcaaattc
    21421 aggtggcgca atattcatta acatcgctag aataacagct aaagttaaag ctgtattcac
    21481 ccattttatc catggttgtg ttcgtgcacg tccttttaca ggaaacctta catcttgatc
    21541 tcgttcatat acttcaacta atttatgtac atctatatct tgtgtttgcg gtaattcatt
    21601 tctctctatt gcttttttga tacgtttttg ttctttaaat ccaagatata ccgcaaataa
    21661 cataacaaga atgaaaccta ttatttgaat aggtattaat ccataccata attcattgac
    21721 acttttggct tttaacactg cagctacacg agccattgga cctccccaag gtaccatgtt
    21781 cataatcgcc gcgcttaatg ctaatagtaa aatcaataaa tatttattca tatttaacgc
    21841 tttatataaa ggtaataatg caggaataga aagcaaaaat gttaccgcac cggccccatc
    21901 taattgggct attgtgccaa ttaaagctgt cattgcacag acaatgacga cattgcctcg
    21961 tgtcattaat attaagcgtt tgacaagcgg cttgaataaa ccactatcat tcatgatgcc
    22021 aaagaaaata atggcaaaga taaacataat aacaacgttg atgacttgat ctaatccttt
    22081 agcaaaaaat ccaaccaaat ctgtcacact atatcctaaa atcattgccc ctaagcaagg
    22141 tatgattgtc atacctacaa ctggatttat ctttttggca atgagtaaac ctacaattga
    22201 aataataata atgagcccca ttactgttaa ccacatatta tcactattca tattattttc
    22261 tccctccact tttaatacaa tttacataat ccccctcttt aacttaaata taataattaa
    22321 tataattttt tatatttaag ttaactcatt ttatcaaaaa tttctttttt gtgtaactat
    22381 caatagtgaa gtttgatttt cctacttgat aacatggcat gactaatcct tgtatatcct
    22441 gtcctgtatt tcattttgat ttatcatttt tattattgct ttctattgca caaaaaatct
    22501 ggctaaaggt cgctatgata gtaacgactt caaccagatt tcaatttatc catctatttt
    22561 attaagtttg ttctacgtat ctttttctct attgtaatat tcatatttaa aacgcatatc
    22621 attatcgctt aaatacttca ttattagact attcacaaag ccgcccatgt cttaatttca
    22681 atgattaagc gttaaagtta aaataagaag acttacctta gacggtccgc tattattgtc
    22741 ttacatccaa ccacgctaaa aattgagctt gtttgtcatg atttaaatat tcttgtgaca
    22801 caatttgtga cagtaactgt tgcttttcgt tatatgttat atctagtaac tttattttct
    22861 gtcggcaagt atataaaaag tcgatatacg aactgtatga tggtggatat aacgcctcaa
    22921 gctctgccat aattgatttt gtcaacttag gactcgcacc atcagttgat acactgatag
    22981 ttagcttgtc gcggtgtagt gcacttggaa atacaacatt gccatttgat gcatctccaa
    23041 cattattaaa aagggcatgc tcaggtaagg cttgttttac cgcttcattg acacgtggct
    23101 cattggttgc tgcaataact agatacgcgt ctacaatatc gcttggttca aactcttttt
    23161 ctttccatat gacgacaccg ttatctacca tattttgaag tttttcagtg attgtcggac
    23221 tgatgaccgt catatgttca acgtattgac ttaatgtttg tgcccgacga cttgcaacga
    23281 cgcctccacc aactatgacg acatttttat ttgttaaatt tatcattaat ggcatattca
    23341 tgttgagcaa catcctttat ataattttac atcattacac cttaaaatat ttaacacatt
    23401 gaagcattaa taaacatcac gttgatagcg ttgttgttgt ttcatttgac gcaatatcgt
    23461 ctcagcttcg tcttgagaaa tatgacgttc ttttaccaat acatctttaa tggcttgatg
    23521 gacatccttc gccatacatt tttcatcgcc acaaatatag attgctgcgc cttgctcaat
    23581 ccattcattg aaacgttcac tttcttccat tatacgatgc tgtacatatt ctttgtgttc
    23641 ttggtctctt gaaaatgcta aatctacgcg tgttaagttt ccattttcaa gccattcttc
    23701 tatttcttct tcatataaaa agtcagaact acggtgttga tcaccaaaga acaaccatgt
    23761 ttttccagtc ataccaagtt cttcacgttc ttgtaaatat gctctaaaag gagcaattcc
    23821 agtacctggt ccaatcataa taaccggtat atcttgcttc atcggaaatt tgaagttcgg
    23881 atttttcttc aaataaattg gtactatatc gcctggttta atacgctcag caaaatgaac
    23941 cgagcataca ccttttctct cacgtccatg tgcttgataa cgaaccgtac caacggtaat
    24001 atgcacttca tctggcgttg ccataaaact actagaaatc gaatactctc ttggtggtaa
    24061 ttttctaagg atttgataca tattctcagg ttgtaattct atagttggaa aatctgttat
    24121 taaatctata aagtcctgat ttataacata ttcacgcgcc catgactcat cttgaatacg
    24181 ttcagataat tcttcattgt caaaatagat atctgcattt ttcaataatg gcaatgttaa
    24241 tttagtaaat tcaaaatgtg atgttagtgc ttcaacaata ggaactgtat caccatgatc
    24301 attaattggc accggagatt gcggatccca acctaacatg gatattagtt tttcaaccaa
    24361 ttcagggtcg ttttgcggta atgctactat acaatctcct ggttcatatg attcactaaa
    24421 atcatcaagt aaaaattcta tatgtcgtgt ttctttattt gaatcggtac catttaaatt
    24481 gatattcgct aaaacttctg cttggtatgg atttgattta gaatatttct tttctttggc
    24541 agacttaatt gattcactta tcaccgattc actttgaata ccttctgatg tggtatcaat
    24601 catattaatg atgtctgcca tccacttttc tgcgtcttct tcataatcaa tatcacaatc
    24661 tacacgctta catatacgct cagcgcctag attttctagt aaagcatcta catctttacc
    24721 ggcttgacag aaaaattcat atgtttgatc acctaaagct agtactgaat atctcacatg
    24781 atttaaatta ggtgcgttat cgtcttctaa aaattcaaag aaatcccatg cattatcggg
    24841 cggttctcct tcaccatgag tagacgtaat aataaataaa tcttctaact gtgcgatgtt
    24901 tgtcgtatca tattcatcca ttgacatcaa aacaacttga tgtccgatat cacttaatcg
    24961 ttctgaaaat atttcagcca atcgcatggc attacctgat tcagaaccgt atagcacagt
    25021 gacatgacgc tgattagctt cgatatgtgg ctctttattt tgtaacatat acgttgttga
    25081 agttgcttgt tcttctgata tttgtgattg ttgccacact tctgtctcta attgttgttg
    25141 attactatca cttgtcgtat cgctactatt agctagtaaa aacccactaa gccattgttg
    25201 ttggctctct gttaatgttt gcagcagatt gttaatctct gtaacttgtt tttctgtaaa
    25261 tggactatta gatgtattta atttcaaata ttttcacctc aataaacttg aaatagatga
    25321 ttgactcatt ttttatcgat agtttagtca attttttaat atgtatggta taaattaaaa
    25381 caaacttgag ttgtgtctga tagttatact tacaaatatt tacaaccttc atgttgcttg
    25441 aatgacacag taattcagac aaaactttga ttatgtcgtg tcagttatta atgcatacag
    25501 taatgcatcg ttgttatttt ttatttacta tttattatgt accaaatcag cctttcagta
    25561 aaataggtca aattactgat tttctaaata taaaatgcct cctaatgaca tactattagt
    25621 acatcattaa gaggctcttg tgttatttgc atactaagcg ctcaatttta aatttaagat
    25681 gaagattctt gcaataatat ttctatattt gccgatatat ccaatggatc ttccattggc
    25741 aagaatcgat ttacaacatt gccttgtcga tcgattataa attttgtgaa attccatttt
    25801 attggggacc caaagattcc tggttgttca ttctttaaat gcgtaaataa cggatgttca
    25861 tcgttcccgt tcacagatat tttagctagc actggaaatg taacaccaaa tttctcacga
    25921 ctgattttca agatttcttc attagaacct ggttgtcgat tgtcaaaatt attattcgga
    25981 aaactcaaca ctacaaaccc acgatcctta tatttttgaa acaaagtctc tagttttttc
    26041 aattgttcgc tatatataca ttctgttgca gtattaacaa ctaaaatcac tttacttcta
    26101 aatgcttcta atttataagt taagccttta taatcactta cttcgatatc atacacattt
    26161 ctattattca taagacaccc ctacacagcc ttttttatat tgaatatgtt ctttttagaa
    26221 tgttctgata aaataagtgc gcgtttacac cgcgaataca cattatatag cgcgatacat
    26281 ttttcaaaca cacgataaat aatgttcgag tttatgttgt tgctcaacct atccgattta
    26341 ccgtcttttt tcacctgtct tactttatta aaataatcac attgtatagc tgtattagtc
    26401 cagctacaat atctttcgtt ataacccctc attataatca tccttatttt ctatttttaa
    26461 aaagacaatt agaccgctct ttaaactata gattaatact taagttaaac tcatacatac
    26521 tgataccata cgttaaatct aacaatttaa aattcgttat aactatggat taaagagctg
    26581 cccaactcat ataatcctta aaaacttcac atgtgattgt ttattaagcc ctcctttatc
    26641 ttattaagta tccttataac ccttttaaaa ttaaactgac acactcatac attgttacat
    26701 gcgacgataa acgtcatatt attgcatatc attaaaacaa gtcactttgt atcgtgtgcg
    26761 accgaataca tattaaatca tcaataatga ttattcaatt attaaaaata aaaacgaaca
    26821 ttctatatag agtttccact tattgttttt tcagcattgt ctacattact taacattcgt
    26881 gtttgtaagt aatattgacc accaatattt agacacttta taagtatgcc attcatcatt
    26941 tttaatcata ttatttttca tattgatatt tctattcata tatttctgat tgtatattta
    27001 gatataatca tttgttattg gaaaatatat gaaacaaatt tgactcatct ttttcaatat
    27061 ctaaatgaca cgatgcatga tttttgaatt ttgtaattaa tttcctttaa aattagactg
    27121 aattatgaca attttcaaac attttaatgt gtaaatcatt ggcaaaatat acgaattgca
    27181 tttaaatcgt caatttacat atatttttgc gtagtaatca atcgttatca ttgttattta
    27241 tcgttacatt acttcgagta tcagtatgta tttcgggctt cgtttgataa cgacatttct
    27301 ttgtgacatc gcttcatcag tgcaacaata aatacaatga tttcgtgatg ttagttaccc
    27361 attttatgtg ttgcataaaa tatgttgtta taaaacattt taaatcattt tatataaaca
    27421 agctatacat ttttgatatt tcaaaaatat aacttgtcat acaagtaaaa aaaccgacaa
    27481 gacattttat cttatcggtt gaaatttgtt attgttattt gtaatgtttt taggtttctt
    27541 tttaatataa tatatttcag tgaaaataca tgattgatta tgatttcact gaaacatggt
    27601 taattacgtt cttgatgaat aactttagca taaatatagg aagttatttt gtacatcgcc
    27661 atatatagaa acgaaattat aatgacagct agtacgtaac ttgttaaaaa tatatgatag
    27721 ttattaatac ctatcatatt tagtaacgta tatacaatgt tactagaaat taatgtatga
    27781 atcagtgcta ctgttattgg tattgcgaac aagaaagtca tttgatttcg tgttatcttt
    27841 gctattcttc cattatctaa accaagtttt ttcataatgt cataattgtg ctgatttgca
    27901 taggcttctg aaacttgttt atagtacatc attagaaata ttccaatgac aagtacaatt
    27961 gatactacgc cacctacaaa tattagtcca cctgtcagac gatcccaaac cattagcatt
    28021 tctgatttag aatttattga cgcatcgtat tttttcgata gtttttgtat ttgtgatgtt
    28081 gttaatttcg tctttccaga tacattaaag tttatcgata ttgtcgactt cttttgttca
    28141 tgtgcataaa atctttttac tttttgtaat tgattgttat ctttaacaat taaaaccata
    28201 ctatcttgaa tcatcatcaa atttaacgca tgtgcgtcaa gttgtttcac tttaaagact
    28261 tcattattaa gaccgacctt agactgcttt ttaaaaatag gtacattcgt aatcatacct
    28321 atactttgat tgtctaagtg taatttgttt tggtgatatc gattataatc ttgcacagta
    28381 agtgctgtga tcattactga ttgcttagaa aatatcgagc cttcattacc aatgaagtct
    28441 attggaatat catcactagc ctgttttaac ttgtaataag cacgattctt ttctaaagaa
    28501 gctctaaata atgtcgtttc atatactttg aagtcttttg cattaaccga accctgtata
    28561 tcacgtttaa tattctcaat catttgttga cgttctattt gcgacttaga attgtcgtta
    28621 aatgacaaat cataatcatt ggtaatcaat ttcataatgg tatgattcat atcgcgatag
    28681 gttgttaatg tcattgtgag cgttacaatc aaaaatgtac acagcaaagt gatcgttgca
    28741 agactgactg cattcatttt aagacgtaca cgcatcccaa ctaccacaaa aaaataccgt
    28801 ggatgatagt aaacttttga tacctgctgc aatatactaa taattatttc acttatacct
    28861 acaaaaaatg cataagtacc gataataacg aatcctatga caatccatat tttaaaaaag
    28921 gcaccaaacg tcgtatcttg ttgtaatgca ataaagtagc ctaaatatag tgctgcgctt
    28981 cctataacaa ttaaaacgta acgcaaccat cgtgatatga cactggaatc agaacgatgt
    29041 tgataagtta tcggtcgttg aaaatttata ctgaacaagt tgaatataag tagcatgccc
    29101 attaatacag caatgataat caaagtaata aacatcgcta cagagtcaaa tggataatac
    29161 cttaacgtcg caacctcact gcccattatt ttctgtataa acaagaaaaa tatcgcacca
    29221 agtaagtatc cgccggcaat actaacgact gaaattatca taaattgtaa gatagtttcc
    29281 atcactacaa ttaaacgcat acttttcttg gtcatgccca atgtcataaa aatgctaaac
    29341 tcttttcgtc tttgtgacat cataaagtga tttgcataga aaataaaaat aaaagttaaa
    29401 agcgccataa aaaaattagc tatgataata aatggtacta ggaagtcatt cttctgtttt
    29461 atgtagctat ttaacccaat tgacacaagc gtatattcaa tcatgaatag tacacttacc
    29521 gctaaaatga atggaatgat tacaagtcgc tgcgtaataa attgacgtcg cactatgtgc
    29581 cataacaatc ttaacttcat atattgacac ttcctccatt cacaagtgct aagctatctg
    29641 ttattcgttg ttgaaaagct aattgacttt cttcaccacg atatatttca tgatatagac
    29701 gcccatcttt aataaaaatg actcgctctg cataagacgc atcgatattt gaatgagtta
    29761 ccattaaaat tgtctgttcc aattgatgaa tctcttgaaa taacatcatc aatgcctttg
    29821 atgtttttga atcaagtgca cctgtaggtt catcggctag taaaatcgtc ggcttagtaa
    29881 ctaatgcacg tgcaatggca atgcgttgct tctgaccccc tgagatttca gaaggatact
    29941 tgtttaagaa tccctctaaa tgtaattgta ctgtcaactg atgtaccctt tgttctatat
    30001 cttttcgttt agcaccagct aaaattaatg gcatcattat attttcttta ttcgtcattg
    30061 ttggtaaaag attaaaatct tgaaaaacaa aacctaccat ttgttgacga tacaatgctt
    30121 tacttttatt tttcatatta tttaaatgtg cgccatccac aataatgtca ccttcagtta
    30181 gtccatcaaa agaagcaatt aaatttagta gtgtagactt ccctgaccca gactcaccca
    30241 taattgcaac aaattcacca gctccaactg ataaattcat ttgattaagt gctgtcgtag
    30301 cattcaaacc tttaccataa acctttttta catgtttcac ttctagcaac atggcatgca
    30361 cctcatttct ttgttagttc tatattaaaa caaaaaaata ctaataacat ttaaattagt
    30421 gaaaaaatgt tactagtatg cttacaatat tgaaagtttt tattcatctg gaaattgaat
    30481 cgtaaatgtt gtaccctcat tttgtttaga tacgactgaa acaggatggt ttgtgtgagt
    30541 tgaaatttgt tttacgataa ataagccaat cccacttgag ttactttgac gctggccatt
    30601 ataacctgaa tagcccttat caaatatttt aggcaagtcc gcctcactaa taccgatacc
    30661 attatctttt acatataatt gattggattg ctcatcaaat tcaatccata tatctttacc
    30721 tctcgcatac ttaagtgcat tatttattaa ttgttctatc attaaagagg tccatctaac
    30781 gtcagttaat acttcgtgat gacaaggttc ataatggatt tttgtttttt gatcaataaa
    30841 ctgtattgaa tatttcataa taattgggcg aatgatattg ttaatcgaaa ttttagtgac
    30901 agaaatatca gaagtttcat ttaataactt taaataacta agtgctaaac ttgtatagtt
    30961 atcaatttga ataacctctt gacgaacacg attcacaaca ttaggctcat ctctttcaag
    31021 taacagttgt gctgcagtaa tgggtgtttt catttgatgt acccatgtta aaaagtagct
    31081 ctctacatca tttttatatt caatttgttc atttttaagc tgatacaacg cattttctaa
    31141 gttttcaatt tgttgttgtt ggcttatagt ttttacaaaa cttaaatatt taatacctat
    31201 gaatatgagt aataataata aaataacgcc aagtgctagt aaatatgctt ctaatggcaa
    31261 atgatacagg taaaacatta agccaaataa agcaaaaata actatgacta ttgctatttc
    31321 ctgagtaata cttttaagaa aggtcattgc attcacccta tactttatat ccgacatttt
    31381 tctttgtaat aataaaatca ttaacgccaa tagtatttaa ttttttacgc aggcgcgtca
    31441 tgttaacagc taatgtattg tcatctatga agttttctga ttcccaacat ttttcaatta
    31501 aagccgttct acttacatat ttatcttcat tttgaaataa taactttaat atttgtaatt
    31561 cagtcaaaga tagctgtatg ttttgttctt gatacacgac ttttgcttca tctaatatta
    31621 atgtacaacc tttaaccgtc atcgaatcat tagctactga caagtcataa gttcgtctca
    31681 ataatgcttg aattttggca atcgttaatg acaagttaaa tggtttttcg ataaaatcat
    31741 ctccccccat ttgtattgcc ataatttggt ccatattatc aatacgggaa ctaataaata
    31801 taattggcac attagatgtt tttcggattt cttgacacca atgaaaacca tttaacgttg
    31861 gcaaattaat atctagcaat acaagctgag gttgatgttg gttaaagata gacagtatat
    31921 catcaaattg ttcaacgaca ataacaccgt aattccattt tttaagttca gatgctaaac
    31981 tttctgctat aacaaaatca tcttcaacaa ttaatatttt catctataat cttcttcctt
    32041 caattgaatt atcctttgtt atctttttgt tctttagcct gttgcaatga cagctcttga
    32101 tttgaacttt ccatgtcatt tgtattttga tttagtgtat ttgctttttc tttctcgagt
    32161 tgctttttct tcgtacgttt acgctcttct aaaatagaca acactataaa gaatatgatt
    32221 aataatggag ataacattac tagtatcatt tttccacctc aaattatatt taattctata
    32281 ttttcacacg cttctattct aacgctttct ataacaaatt gtcatatata ttcatttttt
    32341 gttattctaa atcactctgt ttacatattt ttaactaaaa ctacataatt gctcaaaatt
    32401 cctcttttac actgaagaca tagtcatata ctcaggagga tgtcttatgt tatcagttaa
    32461 aaaagccaca aaatttgcag ttgctaacct tattatcgtg tcaacagttt tcagttctat
    32521 cacacctgca attgcgcaat ccgataaaag ttctaaagat gaaagtttcg cggttggtaa
    32581 tactaaaaat cctaaaaatg ttatcttttt agttggcgat ggtatgggtc catcatttaa
    32641 cacagcttat cgttattata aaaatgatcc aaaacagaat attactgatt ctgcagctgg
    32701 cggaacagcc tttagttctg gccataagac atataatggt gccatcggtg ttgacagtaa
    32761 caagcagaaa gtaaagacgg tgcttgaacg tgcaaaagaa aaagggaagt cgactggtct
    32821 tgtttcaaca gctgaattaa cagatgcaac accagcagca tatgctgcac acgtgacttc
    32881 tagagatgat aaaaacgaaa tcgctaaaca attttataaa gataaaatca acggaaagca
    32941 taaagttgat gttttattag gcggtggcgc taaatatttc ggtaaaagta atggcaattt
    33001 agataaaaaa ttcaaaaaag atggttacga ccttgccacg aacagtaagg agttatcaaa
    33061 atctgataaa gataaagttc ttggtttgtt tgcagataaa aatatgccac ttgcaataga
    33121 tgcttctaaa gacgaaccat cattagctga tatgcaacaa agtgcactta gtaagcttga
    33181 gcgtaataaa aaaggtttct ttttaatggt cgaaggtgct tctatagata aatcagcgca
    33241 ttctaacgat attacaggcg ttatgtctga aatggaaggt tttgaaaaag cattcgatga
    33301 cgccattcaa tatgctaaga aacataaaga tacacttgtc gttgcaacag cagatcactc
    33361 tactggtggt ctaacaattg gtaaagataa aggatacgaa tggaatcctc aaccgattaa
    33421 atcgatgaaa cactctggat catatatgac agaaaaaatg gctaaaggtg aagaccctga
    33481 aaaagttatt aatgaaggtt atggctttga attttcacaa gatgatatga aaaaggttaa
    33541 aaaagagaat aaaaagttgc aaaaattact taaaaaaaat aaagatgaaa aatctgcaga
    33601 tgtagaaaaa caaacaaaag ccttacaaca cgctattcag aagccagtaa atgataaatc
    33661 ttatacaggg tggacttccg atggacatac aggcgaggat gttaatacct acgcttatgg
    33721 acctagatca gaatcattta gtggtaatat cgaaaataca gaaagcgcaa aaataatatt
    33781 tgatatattc aagtaaagca taaaaaaatt cccgagcact ataacaaggt gttcgggaat
    33841 tttttatggt ttaatttagt actcaatgtt aggtgcttgg ttaacacgtt cttggtattt
    33901 tttaaatgcg aagtataaac cgccaactaa tgttaaaata actgctaatt ttttcatcat
    33961 tcaaactcct ttctaagatg tgttgaaact gagttcaatt aaattatatg tttttattat
    34021 acactttttg acatattttt taaatttaag aatgcgaaga tttttaacat ttctgatgct
    34081 agctttcttt ttcatctttc aaatgcttaa taaaatcaaa gccaagtcgc cctttagcca
    34141 atgcttccat cacatcatac caatccgaac cgacttgttg atatatattt tgcaataatt
    34201 catcttgcgc cttgttcaat tcagcaatga gttgatcgcc tttatccgtc gaatataatt
    34261 ttttgacacg tcgatcagtc tctaaaactt tttcaataat gagaccttgc tcttttaatt
    34321 tttgaagtgt tgcatgtgat ccttgtttag aaatttctaa tatttctagt aatgatttaa
    34381 tagtaatacc aggtaattta ttgataaaaa acaaaaaacg atgatgctga cgactcatac
    34441 catacttctc tataatttca tcagcggtag taataaacgt tttatatgca aaataaaaca
    34501 acatatgctc ataatcgttt ttattggtcg acatgatgat gactcctttc aaagcgttaa
    34561 cctcattata ataaaattta taatgtaagt catacaaatg atgataaaac tataagctaa
    34621 atctaagttt cacgagaaac atttttgtgt atcagcaaat tgcgccaatc atattaatac
    34681 aaatttaatt taaacactta gaaatgttag tcgtgcgtaa atagtttgta tctctcactc
    34741 tgtgtatttt gatgcaatca catattttcc aggaaataat taatcattca ccatccatgt
    34801 tatagcacgc ttaatcgctt ggtcccaata tgcataatca tgatctcctg gtccatcttc
    34861 aaattgataa ggaacatttt tgcgtgataa ataatcgata aaatctaagt tgtcttgata
    34921 taaaaagtct tgtttaccac acataatgag caattttgga atttgtttat cttcagctac
    34981 agctttgtct agcaaataat acggatcatg ttcagttcct ttaacacttg aaagattgcc
    35041 aactatggcc tcttttgaaa aatcattcca ctctagatcc attaaatttt gcgcttcaaa
    35101 cacagcagat aatggtacag ctttggcaaa tttatcgcct tgtgttaatg caaatttaat
    35161 tgtgccatat cctcccatag agtgacctgc tataaaattg tcatcacgct ttttggaaag
    35221 tggaaatatt tgatgaacat aatcatatac ttccaaaata taatcataat agctatgacc
    35281 atatgccatg ttagcatatg cgctatgatc cacattgggc ataatcacag ctaatttgtg
    35341 ttcattcgca tacctttcta tgcttgtata tctcatatat gtcgtttcat cacttgataa
    35401 tccatgtaac aacattaaag tttttaatgg tttagcagtt gtatcgttat taaagaagct
    35461 ttgatcttcc ggtaaaatga ctgtcaaatt ttgatgcata ccaattgttg gtgaatgata
    35521 gtttaatgaa atataagcca tacgtcatga cccctttcta attcttcttt atcaacattt
    35581 tacgcttaaa caattcactt taaaatcatt ttcaacaaaa aaaccgaata caaatgtatt
    35641 cggcctaaaa aagtatttac gctttttctt tatgatcttg cttacgtttt ctaaacaata
    35701 gtaatgatcc taataatgcc atcattgcac caaataaagt tgcatttgtg ttttcgctct
    35761 tatctcctgt ttctggtaaa tcatcagttt tgtgttgttt tgatgcctta ttagaatggt
    35821 ttacttcacc tttaggattt gatggtgctt tctgttcatt atttggtggt gtaactcttg
    35881 aatcggagtc actatctgag tctgagtcac tgtctgagtc tgaatcgcta tctgagtccg
    35941 aatcgctgtc tgagtctgaa tcgctatctg agtccgaatc gctgtctgag tctgagtcgc
    36001 tatctgaatc tgaatcacta tctgagtctg agtcgctatc cgagtctgaa tcgctatctg
    36061 agtctgaatc actgtctgag tctgagtcgc tatctgaatc tgaatcactg tctaagtctg
    36121 agtcgctatc tgaatctgaa tcgctatctg agtctgaatc actgtctgag cccgagtcac
    36181 tgtctaagtc cgagttgcta tccgaatctg agtcactgtc cgaatccgaa tccgggtctg
    36241 gacttggctc tggatccggt gttggttccg gctctgggtc tggacttggt tctgggtccg
    36301 gtgttggttc cggctctggg tctggacttg gctctggatc cggcgttggt tccggttctg
    36361 gctctggact tggctctggg tcaactggtg gtcccggtgt tggatcaact ggatttactg
    36421 ctgaatcacc atcagcactt ccgcctccat aacgtacaac attctcatta ttccaaccga
    36481 aaatactgta atctttacct gtcgctgggt caatattttc ttgaataacc tgtgttttca
    36541 agtttttacc agtattatca tagtgacctt ccactaatac aacatacgtt ttagtaatat
    36601 cgccaaaatt aatacttgct acattttggt atttataagt gattttatcc ttaaactcat
    36661 tcgttacttc tttaagatta gagtcatttg ggtccgcata gtagctatct gataatttag
    36721 atgtatcatt cacttcaaaa attctcagtt ttgtatctgt agcacttact ttaccgctac
    36781 tttcttcgat tttatcttgg tagcctttaa tatacaccca cgtattacct aaaactcgtt
    36841 gcttagggtt aacaaatacc gtttgcttgt atgtgttttg gcctgaagct gtatctacac
    36901 caataatttg agaagaaatg ttcgcgccat ttggcttatc aattcctgca attggcgaac
    36961 tatagttata agtaatttta ttattaaaca tttcatccgc aatattaata tttgcatcat
    37021 atgttcctga tttaggtgcc tttgctcggt ctgtaaataa aggtaatgaa aattgtccgt
    37081 taatattttc tttatcattt acataatctg taaagacaaa tgtatacgtc ttagtcaaga
    37141 tattataagt cgctgtcgct acaacatcac cattcgtact tttaatgtct gcaattggca
    37201 tcgtattatt tgaattagag taatccacgt ctccattacc agttaaacta tctggtaact
    37261 tcgctgtaaa ataatcccct gatttcactt tatctgtcac tgtaaaattt gccgccataa
    37321 atgtgttacc actttggtta gggtcgaatg tagtcttttc taacttgaaa tcacttgccg
    37381 taactttatc atttacattt gtacctttag catcagcagc atttactaca ggttcagcaa
    37441 ctgcaagact acgtacagct ctcgttctaa cacttggttt actagttcct tgcgcattgg
    37501 aaatcgtttg tggtgatgat tgtggtaaat ctaatgtttg aggattttta agctcactgt
    37561 ttgttgctat gttattagca tcattcgttg ttttattatc tacttgagaa tttgcttctt
    37621 gaggaacagt ttgatcttgc atttttgcag cagttgcttg atctttaatt gccgtcggtt
    37681 gaggtgtttc atttgttgaa gctggctctg ttgtagtggt attgctcgtt tgtgtagaca
    37741 ttggttttgc tgtgctatct acattcgcac tgtttgtgtt tgcactaata tcagatgtat
    37801 cattagccgt tgtatttaat tgaggtgttt ctatcatatt gtttttttcg gaatctgcac
    37861 ttgcattatt tttcgaagat tgcgttgtat cgttcgattg ttctgaagct tgtgcttgat
    37921 gattgcctat cccaaatagt atagttgccc ctactattac tgatgtggta cctactgtaa
    37981 aacgtctaat cgaatactta ttctgcttat tcgacaaata atcaattctt tttttcaaaa
    38041 atattactcc atttcaattt ctagattagt ctaaattgta taatgaaata agaattatat
    38101 caattgcttt tcgaaaaaaa ttacgtaaaa tttgttttct tcc
//
LOCUS       DAPSKH010000021        37697 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPSKH010000021 DAPSKH010000000
VERSION     DAPSKH010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 37697)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37697)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37697
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.021"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            23..229
                     /gene="copZ"
                     /locus_tag="RPH49_001158"
     CDS             23..229
                     /gene="copZ"
                     /locus_tag="RPH49_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDY5124324.1"
                     /translation="MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSV
                     QYDDSKVAVSQMKDAIEDQGYDVV"
     gene            complement(319..1317)
                     /locus_tag="RPH49_001159"
     CDS             complement(319..1317)
                     /locus_tag="RPH49_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDY5124325.1"
                     /translation="MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVA
                     GYDGLSLSQQIPLSEHVYKRLNELGIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYS
                     PNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRV
                     VADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLF
                     NAELFKHFKKGAVFVNCARGSLVDTKALLEALDNGVIKGAALDTYEFERKLFPSDQRG
                     KTLNDPLLESLIDREDVILTPHIAFYTEAAVENLIVDALDATLDVLQTGDTRLRVN"
     gene            complement(1340..2494)
                     /locus_tag="RPH49_001160"
     CDS             complement(1340..2494)
                     /locus_tag="RPH49_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDY5124326.1"
                     /translation="MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQG
                     IIDHFQQALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGL
                     VAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSKVDSQIID
                     KTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILAS
                     ENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIY
                     ALNHYDDFLEEQSNIFKARRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQ
                     FLVKEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE"
     gene            complement(2921..4429)
                     /locus_tag="RPH49_001161"
     CDS             complement(2921..4429)
                     /locus_tag="RPH49_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5124327.1"
                     /translation="MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNTNVGGRMNQLKK
                     DGFTFDMGPTIVMMPDVYKDVFTMCGKNYEDYIELRQLRYIYDVYFDRDDRITVPTDL
                     AELQHMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAK
                     LKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIK
                     GGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTA
                     DFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDD
                     FRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSD
                     EALTQQIKEIIYRKLAAIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLA
                     QSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIERGV"
     gene            complement(4441..5304)
                     /locus_tag="RPH49_001162"
     CDS             complement(4441..5304)
                     /locus_tag="RPH49_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="HDY5124328.1"
                     /translation="MTMMAMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVC
                     RKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQ
                     SFYNLIDTVYKDQQFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRL
                     GESLQLINILRDVGEDFENERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAI
                     AEKDFRDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKL
                     FHEINSKYHRI"
     gene            complement(5341..6468)
                     /gene="crtQ"
                     /locus_tag="RPH49_001163"
     CDS             complement(5341..6468)
                     /gene="crtQ"
                     /locus_tag="RPH49_001163"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,4'-diaponeurosporenoate glycosyltransferase"
                     /protein_id="HDY5124329.1"
                     /translation="MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKSLTII
                     IPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDADGK
                     WYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQDEKGLLSVQPYHI
                     TKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANR
                     HIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGADGTKPK
                     IMAAIVLWLFGSIASILGLCLSLKYRQMSVGKMLTVYLSYTTQFIHLHRRVGQFSNLL
                     MVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ"
     gene            complement(6474..7967)
                     /locus_tag="RPH49_001164"
     CDS             complement(6474..7967)
                     /locus_tag="RPH49_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5124330.1"
                     /translation="MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRH
                     ESDGFGFDLGPSILTMPYIFKKIFEYSNKQMSDYVTIKRLPHQWRSFFPDGTTIDLYE
                     GIKETGQHNVILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNA
                     LINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLW
                     YVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIIS
                     NMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAY
                     LNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYA
                     KFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGVVADKKKNKGFK
                     FPKESQYFENLYFVGGSVNPGGGMPMVTLSGQQVADKINAREAKNRK"
     gene            complement(7960..8448)
                     /gene="crtO"
                     /locus_tag="RPH49_001165"
     CDS             complement(7960..8448)
                     /gene="crtO"
                     /locus_tag="RPH49_001165"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl-4,4'-diaponeurosporenoate
                     acyltransferase"
                     /protein_id="HDY5124331.1"
                     /translation="MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKHIIFKSF
                     NFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAEL
                     IHWISILPVIIFNKGPRLVKYINIFYAMITNVPIIIVQRYNRPRLTQLLRILKRRGER
                     HD"
     gene            complement(8623..9390)
                     /locus_tag="RPH49_001166"
     CDS             complement(8623..9390)
                     /locus_tag="RPH49_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5124332.1"
                     /translation="MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSY
                     TYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYT
                     NNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCT
                     YYVFDRVGGKIGSTWGNASNWASAAASSGYTVNNTPKAGAIMQTTQGYYGHVAYVEGV
                     NSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH"
     gene            complement(9751..11562)
                     /locus_tag="RPH49_001167"
     CDS             complement(9751..11562)
                     /locus_tag="RPH49_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDY5124333.1"
                     /translation="MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSG
                     GFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFT
                     LIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLL
                     FPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLL
                     GCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYII
                     SFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIP
                     VYVYVIEIVLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSI
                     VVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLI
                     GDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNG
                     AFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASA
                     GHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK"
     gene            complement(12077..12565)
                     /locus_tag="RPH49_001168"
     CDS             complement(12077..12565)
                     /locus_tag="RPH49_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124334.1"
                     /translation="MTINIIEYNRSYKEELIEFILSIQKNEFNIKIDRDDQPDLENIE
                     HNYLNSGGQFWLAINNHQNIVGTIGLIRLDNNMSALKKMFVDEGYRNLKIGKKLLDKV
                     IMTCKEQNIDGIYLGTIDKFISAQYFYSNNGFREIKRGDLPSSFPKLDVDNRFYYRNL
                     KG"
     gene            complement(12851..13552)
                     /gene="isaA"
                     /locus_tag="RPH49_001169"
     CDS             complement(12851..13552)
                     /gene="isaA"
                     /locus_tag="RPH49_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase IsaA"
                     /protein_id="HDY5124335.1"
                     /translation="MKKTIMASSLAVALGVTGYAASTGHEAHAAEVNVDQAHLVDLAH
                     NHQDQLNAAPIKDGAYDIHFVKDGFQYNFTSNGTTWSWSYEAANGQTAGFSNVAGADY
                     TTSYNQGSNVQSVSYNAQSSNSNVEAVSAPTYHNYSTSTTSSSVRLSNGNTAGATGSS
                     AAQIMAQRTGVSASTWAAIIARESNGQVNAYNPSGASGLFQTMPGWGPTNTVDQQINA
                     AVKAYKAQGLGAWGF"
     gene            complement(14160..15215)
                     /locus_tag="RPH49_001170"
     CDS             complement(14160..15215)
                     /locus_tag="RPH49_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDY5124336.1"
                     /translation="MTSIKTITPKDFIFRVLSGVAIGIVAGLVPNAILGEIFKYFMDY
                     HPIFKTLLGVVVAIQFTVPALIGALVAMKFDLSPLAIAVVASAAYVGSGAAQFKNGAW
                     MITGIGDLINTMITAAIAVLFILLIQHRVGSMALIVFPTVVGGISGAIGVLILPYTKM
                     ITTAIGNMVNGFTELQPIVMSILISMVFSLIIISPLSTVAIAFAIGITGLAAGSASIG
                     ISATEAVLIIGTSKVNRLGVPLSVFFGGVKMMIPNMVKYPILMLPILTTAIVSGLVSA
                     LVGIHGTKESAGFGFIGMVGPINAFKFMEVDSAWLSVLLIVVAFFVVPFVTAWLADII
                     YRKVFRLYTNDIFKFMG"
     gene            complement(15342..15470)
                     /locus_tag="RPH49_001171"
     CDS             complement(15342..15470)
                     /locus_tag="RPH49_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124337.1"
                     /translation="MDFKNEDKIKVYCNNMFEKLPISLSKNSEFCDILFFIVLSYR"
     gene            15607..16194
                     /locus_tag="RPH49_001172"
     CDS             15607..16194
                     /locus_tag="RPH49_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001807464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5124338.1"
                     /translation="MLGSEQTMESKSIDPRIVRTKQLLVDAFLKISREKKLSQITVKD
                     ITDIATLNRATFYAHFTDKEDLLDYTLSVTILKDLNDNLSISNVINEKVLRNIFISIA
                     SYIKDAAKSCELNSEAFCNKAHQRINNELEDIFAIMLENSYPEHQRDIIVNSASFLAA
                     GISGLALHWFNTSQETADVFIDRNLPFLIHHIAHF"
     gene            16392..16892
                     /locus_tag="RPH49_001173"
     CDS             16392..16892
                     /locus_tag="RPH49_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124339.1"
                     /translation="MTSIFVFAYLNNTSDNMLFRQQMIYACLLANVRHSSIVCLNNTC
                     RIVDIRCLNTKIGGIDVSETDESQGFERTHNILNINQSSLGVVTYITNKLKSTLKQHI
                     IIACGKKRIDYRLSYNFYTTYYDNVEIKKINCEYTYAMPIAILIRHMMSFDNDYFFAQ
                     LRHPVL"
     gene            17112..17342
                     /locus_tag="RPH49_001174"
     CDS             17112..17342
                     /locus_tag="RPH49_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDY5124340.1"
                     /translation="MKILDRINELANKEKVQPLTVAEKQEQHALRQDYLSMIRGQVLT
                     TFSTIKVVDPIGQDVTPDKVYDLRQQYGYIQN"
     gene            complement(17746..18123)
                     /locus_tag="RPH49_001175"
     CDS             complement(17746..18123)
                     /locus_tag="RPH49_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5124341.1"
                     /translation="MIQSMWFNLHVQDLEKSAQFYKALGFKINRNPQMLDKMVGIQIG
                     QTTVILIENKHFQNVSQQSLNTEPNEVMISLGVNTNEEVDQLVNKVKEAGGTVVQEPT
                     VSQGFYGAMFKDLDGHHFNFLVC"
     gene            complement(18140..18961)
                     /locus_tag="RPH49_001176"
     CDS             complement(18140..18961)
                     /locus_tag="RPH49_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NmrA/HSCARG family protein"
                     /protein_id="HDY5124342.1"
                     /translation="MKDILVIGATGKQGNAVVKQLLEDGWYVSALTRNKNNRKLSDIG
                     HPHLSIVEGDLSDSDSLQSAMKGKYGLYSIQPIVKDDVSEELRQGMKIIEIAEQENIQ
                     HIVYSTAGGVNRNRTGPHFEVLAKIENRLMESNINATVIKPSFFMDNFLRIAKVEDER
                     ITLPEFINPNIKFTMISSIDIAKIASYIFAHPQSFTHQSIEIGSDEVTLSEAATIFSE
                     VTGKSTVIEGEFVSSVAEKQWLEEKGYEVDFELMAEINPTRLSLSDWLKVQDYNK"
     gene            complement(18980..19279)
                     /locus_tag="RPH49_001177"
     CDS             complement(18980..19279)
                     /locus_tag="RPH49_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2316 family protein"
                     /protein_id="HDY5124343.1"
                     /translation="MSLNKEQRRITAEELQAHFEASTLSVQMIAEKLNVTTEDVEKAL
                     AMKAPLGIFSHQLQRFIHLVWDVRNVINDNIKENGQTPEPYTYLKGEKEDYWFLR"
     gene            19410..19967
                     /locus_tag="RPH49_001178"
     CDS             19410..19967
                     /locus_tag="RPH49_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5124344.1"
                     /translation="MRKDAKENRQRIEEIAHKLFDEEGVENISMNRIAKELGIGMGTL
                     YRHFKDKSDLCYYVIQRDLDIFITHFKQIKDDYHSDYEVMQVSLDYLLQFKIDNKALL
                     QCIEAGNNKLRFYQSAFYQELFNFYYDLFKSDDDIYKKFKTDMLLQALSTSVFAFQIE
                     HRHISIEAYRNYLLNIYLDEVERND"
     gene            19960..20664
                     /locus_tag="RPH49_001179"
     CDS             19960..20664
                     /locus_tag="RPH49_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="HDY5124345.1"
                     /translation="MTKIVLITGGNKGLGYASAEALKALGYKVYIGSRNDVRGQQASQ
                     KLGVHYVQLDVTSDYSVKNAYNMIAEKEGRLDILINNAGISGQFSAPSKLTPRDVEEV
                     YQTNVFGIVRMMNTFVPLLEKSEQPVVVNVSSGLGSFGMVTNPETAESKVNSLAYCSS
                     KSAVTMLTLQYAKGLPNMQINAADPGATNTDLVGDFSNNSKHVSEGIKPIIQLATIDA
                     DGPTGTFINGDGEMPW"
     gene            20762..21772
                     /locus_tag="RPH49_001180"
     CDS             20762..21772
                     /locus_tag="RPH49_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDY5124346.1"
                     /translation="MKSITFEEHYVIEDIQKETMNAISADPKGVPMKVMLEGLEKKTG
                     FTNADELSHHDERIQFMNNQDVQIQVLSYGNGSPSNLVGQKAIELCQKANDQLANYIA
                     QYPNRFVGFATLPINEPEAAAREFERCINDLGFKGALIMGRAQDGFLDQDKYDIIFKT
                     AENLDVPIYLHPAPVNSDIYQSYYKGNYPEVTAATFACFGYGWHIDVGIHAIHLVLSG
                     IFDRYPKLNMIIGHWGEFIPFFLERMDEALFAEHLNHPVSYYFKNNFYITPSGMLTKP
                     QFDLVKKEVGIDRILYAADYPYIEPEKLGVFLDELGLTDEEKEKISYTNGAKLLGLSS
                     NN"
     gene            21792..22622
                     /locus_tag="RPH49_001181"
     CDS             21792..22622
                     /locus_tag="RPH49_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5124347.1"
                     /translation="METLELQGAKLRYHQVGQGPVLIFIPGANGTGDIFLPLAEQLKD
                     HFTVVAVDRRDYGESELTEPLPDSASNPDSDYRVKRDAQDIAELAKSLSDEPVYILGS
                     SSGSIVAMHVLKDYPEVVKKIAFHEPPINTFLPDSTYWKDKNDDIVHQILTEGLEKGM
                     KTFGETLNIAPIDAKMMSQPADTEEGRIEQYKRTMFWSEFEIRQYTHSDITLDDFTKY
                     NDKITLLNGTDSRGSFPQDVNFYINNETGIPIVDIPGGHLGYIQKPEGFADVLLNMWS
                     "
     gene            22763..23788
                     /locus_tag="RPH49_001182"
     CDS             22763..23788
                     /locus_tag="RPH49_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDY5124348.1"
                     /translation="MKAIQIKKYNKNRDVQIRDITIPEIKSTEVLVKVAYAAINPLEN
                     LTINGSVKLIQNYKMPQTIGNELTGTIVKVGSKVEDYKLGDKIYSRLPIDRIGAFAEY
                     VSIESNAIAKLPKNLNLKTGAAVPLTGLTAYQAITEELKAIPGKTLFIPGGSGSFGQM
                     AVPIAKSLGLKVIVSGSPRLKDQFLAKGVDQYIDYKTENYCEVLSDIDYVIDTLGPNE
                     FDKELSVMKPGGTIVSLINAPNKAFAVKNNFSPFKKLLFGLAGKKFDKKAQKKSIDYR
                     FIFVRSDGEQLKILNKIIEQNNIIPDIDDHIFTIDEIDKALDYTFNHHTNGKVLIRID
                     NSDNTIY"
     gene            complement(24009..24899)
                     /locus_tag="RPH49_001183"
     CDS             complement(24009..24899)
                     /locus_tag="RPH49_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDY5124349.1"
                     /translation="MKIVIIGGFLGGGKTTVLNHLLAESLKESLKPAVIMNEFGKMSV
                     DGALVSEDIPLSELTEGCICCAMKADVSEQLHQLYLKEQPDIVFIECSGIAEPVSVLD
                     ACLTPILAPFTTITHMIGVVDASMYKHIKSFPKDIQGLFYEQLAYCSVLFVNKIDSAD
                     VETTSKLLKDLEVINPEADIQVGMHGSVTLPISVRQMTVTSDNKHESLHKTINHQFVQ
                     SPVKCTKAEFIKRLACLPSHIYRLKGFMTFEDTAHTYLIQFTQGQYELTPVAFSKKVP
                     EYLVLIGKGISKEDYQCLEQ"
     gene            complement(24999..26339)
                     /locus_tag="RPH49_001184"
     CDS             complement(24999..26339)
                     /locus_tag="RPH49_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter B"
                     /protein_id="HDY5124350.1"
                     /translation="MLEVKYDMRTGHYTPIPNEPHYLVISHADKLNATEKAKLRLLII
                     KQKLDISLAESVVSSPIASEHVIEQLTLFQHERRHLRPKISATFLAWLLIFLMFALPI
                     GIAYQFSDWFQNQYVSAWIEYLTQTTLLNHDILQHILFGDYGVLSLGTYSLVWALPVV
                     ILISLSTAIIDQTGFKSWMIWAIEPSMLRIGLQGNDIVPLLEGFGCNAAAISQAAHQC
                     HTCTKTQCMSLISFGSSCSYQIGATLSIFSVAGKSWLFMPYLILVLLGGILHNRIWLK
                     KNNQQLSVPLPYDRQLHMPNIRQMLLQMWQNIQMFIVQALPIFITICLIVSILSLTPI
                     LNVLSQIFTPILSLLGISSELSPGILFSMIRKDGMLLFNLHQGALLQGMTATQLLLLV
                     FFSSTFTACSVTMTMLLKHLGGQSALKLIGKQMLTSLSLVIGVGIIVKIVMLII"
     gene            complement(26333..27439)
                     /locus_tag="RPH49_001185"
     CDS             complement(26333..27439)
                     /locus_tag="RPH49_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="HDY5124351.1"
                     /translation="MQHHKVAIIGAGAAGIGMAITLKDFGITDVIILEKGTVGHSFKH
                     WPKSTRTITPSFTSNGFGMPDMNAISMDTSPAFTFNEEHISGETYAEYLQVVANHYEL
                     NIFENTVVTNISVDDAYYTIATTTETYHADYIFVATGDYNFPKKPFKYGIHYSEIEDF
                     DNFNKGQYVVIGGNESGFDAAYQLAKNGSDIALYTSTTGLNDPDADPSVRLSPYTRQR
                     LGNVIKQGARIEMNVHYTVKDIDFNNGQYHISFDSGQSVLTPHEPILATGFDATKNPI
                     VQQLFATTNQDIKLTTHDESTRYPNIFMIGATVENDNAKLCYIYKFRARFAVLAHLLT
                     QREGLPAKQDVIESYQKNQMYLDDYSCCEVSCTC"
     gene            complement(27774..28070)
                     /locus_tag="RPH49_001186"
     CDS             complement(27774..28070)
                     /locus_tag="RPH49_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4176 domain-containing protein"
                     /protein_id="HDY5124352.1"
                     /translation="METIGSIIYLKEGSQKLMIINRGPIVEIENQKYMFDYSGCKYPI
                     GVVEDEIYYFNEENIDSVIFKGYSDQDEVRFQELFDNMKQNLDSEIQRGKVTQQ"
     gene            complement(28058..28426)
                     /locus_tag="RPH49_001187"
     CDS             complement(28058..28426)
                     /locus_tag="RPH49_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124353.1"
                     /translation="MSNKLDEINKIITAKHEQMDDLYDEKREVKALIDESDALNHSID
                     QLYQHLGERYYSSNMASRMEQFRDEFHFAKRRSTVALHEQQQQIQHGIRKAEEEMIDL
                     EMRRNVEIETVTKEENKWKQ"
     gene            complement(28441..28719)
                     /locus_tag="RPH49_001188"
     CDS             complement(28441..28719)
                     /locus_tag="RPH49_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR04197 family type VII secretion effector"
                     /protein_id="HDY5124354.1"
                     /translation="MMSTVQSDIFKTNSASSSIKSAVETCNNVSKPDKDESTTVSGNN
                     NAHSVIDDLMSKNQSVAEAIRTASDNIQKVGEAFDQTDVMIGNEIGKN"
     gene            complement(29056..29922)
                     /locus_tag="RPH49_001189"
     CDS             complement(29056..29922)
                     /locus_tag="RPH49_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001005521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDY5124355.1"
                     /translation="MNEQWLEHLPLKDIKEISPVSGGDVNEAYRVETDTDTFFLLVQR
                     GRKESFYAAEIAGLNEFERAGITAPRVIASGEVNGDAYLVMTYLEEGASGSQRQLGQL
                     VAQLHSQQQEEGKFGFSLPYEGGDISFDNHWQDDWCTIFVDKRMDHLKDELLNRGLWD
                     ANDIKVYDKVRRQIVAELEKHQSKPSLLHGDLWGGNYMFLQDGRPALFDPAPLYGDRE
                     FDIGITTVFGGFTSEFYDAYNKHYPLAKGASYRLEFYRLYLLMVHLLKFGEMYRDSVA
                     HSMDKILQDTTG"
     gene            30140..31204
                     /locus_tag="RPH49_001190"
     CDS             30140..31204
                     /locus_tag="RPH49_001190"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDY5124356.1"
                     /translation="MYKLIKPFLFKIEPEKAHGLTIDALKTLQKFPVLFPVVDKLFTY
                     KNPTLSQTIQGNTYDNPIGLAAGFDKSCEVPKALEHLGFGALELGGITPKPQPGNPQP
                     RMFRLLEDDALINRMGFNNIGMNKALSHLRKNAYQVPVGINVGVNKMTPYEARYQDYI
                     KVIDTFKHDVSFFTVNISSPNTENLQNFHDKDEFSMLCQALTAFKKQHDVTVPIYLKL
                     TSDMDFDGLKALLPAITETFDGIILANTTRQRDGLTSANKVEEGGLSGRSLFERNLKL
                     IKYAYQQTNGEFLIIGTGGVFSTEDAIKMMRHGASLIQIYSSLVIEGPGLTKKMNKGI
                     ARYLKDHHFDNVSDIIGLDA"
     gene            31359..31634
                     /locus_tag="RPH49_001191"
     CDS             31359..31634
                     /locus_tag="RPH49_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124357.1"
                     /translation="MTKETDNKKTVATSDNKDTQQQNQPEEDERQGLNGYRKTDLDLE
                     IEQELREMMKTGENETKNDYKKFKVFSLISTLVIVILAIIRFVHKMM"
     gene            complement(31820..32542)
                     /locus_tag="RPH49_001192"
     CDS             complement(31820..32542)
                     /locus_tag="RPH49_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDY5124358.1"
                     /translation="MINAEPIISKMKNQKINYDKVLKKLIGQWEREAIRPKILLHSCC
                     APCSTYTLEFLTQYADIAIYFANSNIHPKNEYLRRAKVQEQFVEDFNRKTGANVKYIE
                     APYEPHKFVKMVKDKELADEKEGGLRCTACFEMRLDIVAKAAVEHGYDYFGSAITLSP
                     KKNAQLINELGMDVQKIYDVNYLPSDFKKSKGYERSIEMCNDYNIFRQCYCGCVFAAM
                     QQGIDFKTVNKEAKAFLEQYPD"
     gene            32896..33345
                     /locus_tag="RPH49_001193"
     CDS             32896..33345
                     /locus_tag="RPH49_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase/bleomycin resistance/extradiol
                     dioxygenase family protein"
                     /protein_id="HDY5124359.1"
                     /translation="MTALFPYIAFKNSKEALAYYEEVFGATDVKRLEVGEEQASHFGM
                     TKEEAQEATMHAEFEVLGVKVLCSDSFGRADKINNGISLLIDYDVNNKEDADKVEAFY
                     EQIKDHSSIEIELPLADQFWGGKMGIFTDKYGVRWMLHGQDYTAIQQ"
     gene            complement(33426..34013)
                     /locus_tag="RPH49_001194"
     CDS             complement(33426..34013)
                     /locus_tag="RPH49_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5124360.1"
                     /translation="MTIDRRIRKSQVAMRNAFIELLHQHQLEEITVQQIADLADVNRS
                     TFYTHYYDKYDLLEKLENQQLEEIRDFIHDEKLNGAVKLSTDNIHQIMTVLIEMIEKD
                     IAFYQLMFRMGKDSNIHEKLYDLIMCHLQRYKNENDQINGIPFSYFMSYVSGAGLSLI
                     RHWVEDPNRIDKVDLIRHFNTIVNQGPATIIKNIQ"
     gene            34156..35838
                     /locus_tag="RPH49_001195"
     CDS             34156..35838
                     /locus_tag="RPH49_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CocE/NonD family hydrolase"
                     /protein_id="HDY5124361.1"
                     /translation="MNQHLLGNPKLTVTHVNEVKAGINHIVVDSVQYGNQEMIMEKDV
                     TVEMRDGEKLYINIFRPNKDGKFPVVMSADTYGKDNKPKITNMGALWPTLGAIPTSSF
                     TPEESPDPGFWVPNDYVVVKVALRGSDKSKGVLSPWSKREAEDYYEVIEWAAKQPWSN
                     GNIGTNGVSYLAVTQWWVASLNPPHLKAMIPWEGLNDMYREVAFHGGIPDTGFYRFWI
                     QGIFARWTDNPNIEDMIQAQQEHPLFDDFWKQRQVPLSQIKTPLLTCASWSTQGLHNR
                     GSFEGFKQAASEEKWLYVHGRKEWESYYARENLERQKSFFDFYLKEENNDWKDTPHVI
                     YEVRDQFYKGEFKSASAFPLPNTEYTPLYLNAENHTLNHAKISSAHVAQYDSEDKRQD
                     VSFKYTFDKDTELVGNMNLKLWVSTKDSDDMDLFAGIKKLDRRGNEVNFPDFNHIENG
                     QVATGWLRVSHRELDQEKSTIAQPWHKHETELKLSQDEIVPVEIELLPSGTLFKQGET
                     LEVVVKGSEIVIGNSTPGMKTRYEHEETVNKGMHMIYTGGKYDSQLIIPIVN"
     gene            complement(35947..36582)
                     /locus_tag="RPH49_001196"
     CDS             complement(35947..36582)
                     /locus_tag="RPH49_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDY5124362.1"
                     /translation="MKKVISLFVAILSVLIFTDNANAENNKPEGVNENSNLIPVRQPD
                     ANYPGPVSDIARVKKLDNLIDGTKDPDVIKQLKDDNEVPNNAVKAKDSKIVSDCRHLL
                     KHPDNLMDGTKDPNVINQLKNANGTSNNSAVNPSIKANDIHTKSNKQMAKQQSIHLDS
                     KSKSVHKQQLKELPKTGVNNESNTAIMVLFIGLILLVVSLVTRFIKLNSHQ"
     gene            complement(36598..37674)
                     /locus_tag="RPH49_001197"
     CDS             complement(36598..37674)
                     /locus_tag="RPH49_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like serine protease"
                     /protein_id="HDY5124363.1"
                     /translation="MTKIFKISFLILLVVIVSSYYGESFVLADNNPIVNSENGSDNNF
                     ESGTIERNQNELYEVGDYSTPLTERVFGKDQRTVVNNILQRPYKQTVLLNMTFSNNRV
                     YKGTGTMIGKDIVLTAAHNVYSKDDKGWAKKIDVYAGVNGQTYTIGKAFSHKFFVSKS
                     WINNAPTKEDIAIIKLNSNLGNKTGYLTLNTRISKGENIEISGFPGDKSDNRQYKGKG
                     KLESFDENEMYYTVDTFSGQSGSAIRDSKNNIIGVHAYGRYNHNSGVRINDLKLDYIN
                     YWIGKYRSHPYNKKVKVIKSKYIYWKNIEITKKGDNKLIKKDKAYTAKLYYNIPNGYK
                     YYSLYDEKNRWMGYFNSNDIKVVK"
BASE COUNT        12302 a         6908 c         5700 g        12787 t
ORIGIN      
        1 gctctaaaag gaggtgaatg ctatgtcaca agaaatttta aatgttgaag gtatgagctg
       61 tggtcactgc aaaagtgctg ttgaatctgc attaaataat attgacggtg tcacttcagc
      121 tgacgttaac cttgaaaatg gtcaagtaag tgttcaatat gatgacagta aagttgctgt
      181 atctcaaatg aaagacgcaa ttgaagatca aggttacgat gtcgtttaat taggcaatat
      241 tcaacgtcat caacaccaaa ttaaaaaatc gaactgatga gaatcccaac aatccaaatt
      301 atctcatcag ttcgattttt aatttactcg caacctggta tctccagtct gcaatacatc
      361 taatgttgca tctaatgcat cgacaattag attttcaact gcagcttcag tataaaacgc
      421 aatatgtggt gttaatatga catcttccct gtcaatcaac gattctaaca atggatcgtt
      481 cagtgttttg cccctttgat cacttgggaa aagtttgcgt tcaaattcat acgtatcaag
      541 tgctgcacct ttaatcacac cattgtctaa tgcttctaat aacgccttag tatctactaa
      601 agaacctctc gcacaattga caaatactgc gcccttttta aaatgtttaa ataattcagc
      661 attaaataga taatgattat atttcgttgc aggtacatgt aatgtcacga tatcagcacc
      721 ttcaaccgct tcctcaatcg tatctttgta atcgacatac gttgcaattt tagcattagg
      781 aaacgggtcg tatgcgacca catcactttg ataaccattg gcaaatatat cggctactac
      841 acggccaatt cgacctgtac caataacagc tacttttaaa tctttaatgg atttcgataa
      901 aatagtaggt tcccatctaa aatcatgctc tcgcactttc gtttgaattt gattaaaatg
      961 acgaaccaca ttaatagcct ggttcacagc aaactccgca attgaattcg gagagtatga
     1021 cggcacattt gacacaatca agttatactt gtttgctaac tccaaatcat atgtatcaaa
     1081 tccagcactt cgttgtgcga tttgtttaat acctagttca tttaatcgtt tataaacatg
     1141 ctctgataat ggtatttgtt gtgatagcga taagccatca taaccagcga caccttcaac
     1201 attgtcatca gttaatgctt ctttagtaat atctacctca acatgatgtt tctctgccca
     1261 cgccttgata taaggcatat cttcatcacg tacactcatg attttaattt ttgtcatttt
     1321 aacatcaccc ttaactttat tattcatata aatatgctag ttctgttaat cttattgcag
     1381 cttcgtctaa tttctggtca tctaacgcca atgaaattct cacataacga ttaccattct
     1441 ctccaaatgg tttccctgga gcaacaagta ttgacttctc tttcactaaa aattgctcaa
     1501 attgctcgct gtcataacca ggcggtgttt ccaaccatac atatatgcca cctttagcat
     1561 gaacaaatgg caaatcagct tttgcaagca tggcttcgaa tcggtcacga cgtgctttaa
     1621 atatattgct ttgttcttct aaaaaatcat cataatgatt caaagcatat attgcggcat
     1681 cttgtaatgc accaaacatc ccagcatttg tgtgcgtttg gtactttttc aaagcttgaa
     1741 tcatatcttt attaccaact gcaaaaccga ctctaaaacc tgacatgtta taacctttag
     1801 acaaggaata aatttcaatc gcaacatctt tcccattttc cgaagcaagt atactaggat
     1861 ttttagcgtc gaaaccgaaa gcaccataag caaaatcatg tacgatttta gtgtctgtat
     1921 ctttaaattt agctatcgct tcatcaaaaa cttctttcgt agctgtcgat ccagttggat
     1981 tatttggata cgttaaataa atgagttttg ttttatctat tatttgtgaa tcaactttgg
     2041 accaatctgg caaataatgt ggcggttcta aattaagtgg gacaggcttg ccatcagcta
     2101 aaagtacacc tgctaaataa tccgtgtagc ctggatcagg tagtaataca tagtctcctg
     2161 gattgataac acatgttggt actgccacta atccattttt tgtaccatat aaaatgcata
     2221 cttcatcttc tttatctaac gtcacattat attgtctttg ataaaaatct acaatagctt
     2281 gcttgaacgc ttctttacca tgaaaagcac catatttttg attttcagga atagttagtg
     2341 cttgttgaaa atgatcaata ataccttgtg gtgtgggccc atcagggatc ccaactgcca
     2401 tattaattaa tggcaatggt ccatgttcga ttttacgtcc catcgttttc ccgaaataac
     2461 tatcagggat atttgctaat ttgttagaga tcatcaaatt cctcctctat cattaaacat
     2521 agcctgggcg actatcataa tcctaacaac ttgtatcgct ctcatttaga tggttacaat
     2581 gacatcgcca ttcaccgtta tgttcaacag aacttatgac acacgttgta ttgaatgaat
     2641 ttattttcat tttaggtagg tacattatta ttgtcaatat taggaatttt cagatcaata
     2701 tacgctcaat cgttatgatt taactgtcat gcatatccgc ttgcgcaacc agtaagatat
     2761 gcttatataa agtataacgc ccatcaaggt acgtattcaa acgtgaacct taacaggcgt
     2821 cattcattgt taaataaaac ttctttagca catacttatt tcactatgcc ttttacgttc
     2881 cccttatact tttctcacat ctttctctta gactactccc ttacacgcca cgctcaatat
     2941 ctttaatcat ttcgtctaca gttattttcg cactcgttaa gacaatagga acgcctgcac
     3001 ctggatgcgt acttgcacct gcaaaatata aatctttata atctctcgat acattttgtg
     3061 gacgataata attactttgc gctaaagttg gcattaaacc gaatgccgaa ccaaatttcg
     3121 catgatacgt ttgctcaaaa tcatttggcg taaagattgt ttctgaaaca atatgcgatt
     3181 ttatatcttc aaatacttca atcgctgcta atttacgata aataatttcc tttatttgtt
     3241 gcgtcaaagc ttcatctgac caatcgattc cgctacctgt tttaagttcc ggcgtcggca
     3301 ttaacacata aataccagtt ttgccttctg gcgcaagtga tttatcagcg accgctggaa
     3361 catacacata aatagaagga tcatatgata aacgtccctc aaatatttct tcaatattgc
     3421 ctctaaaatc atctgaaaaa ataacattat gaagtctcac ttgatctgtc acatcaatat
     3481 ctataccgat atacattaaa aatgctgaac aagagtaatc taagtctgca attttatgtg
     3541 gtggatactt tttaataggt gcaaaatctg gcattaatga ttccgcaaca ctagggaaat
     3601 cagccgtaca taaaatttta tcaaattttc ttatgtcacc attcactttt atcgcatcag
     3661 ctcgtttgaa tttaggatca ataataattt gctcaatttc agcattaagt tcaatattaa
     3721 cacctaaatc tttatttaat tgcgctagcc cttgagccat gccatacata ccgcctttaa
     3781 taaaatgcac accaaacatc atttcaatca taggaataat tgaatatagt gacgggcctc
     3841 gttttggatc aattcctatg tataacgttt gaaacgctaa aagcttttgt atcttttcgt
     3901 tatcaatata atgttcaatt agctgatctg catgatttaa cgtttttaac ttagcacctt
     3961 gcacaagtga cgtcatatta taaaagtcac ttggtttgcg atacgttctt tctaagaaat
     4021 agcgacgtgc aatttcatat tttttataaa catccgttaa aaatgacata aaaccatgcg
     4081 ttgaaccagg ttctatactt tctagcatgt gctgtaattc agctaaatct gtaggcaccg
     4141 ttatacgatc atcgcggtca aaatacacat cgtaaatata acgtaattgt ctcaattcaa
     4201 tataatcttc ataattttta ccacacattg taaatacatc tttataaaca tctggcatca
     4261 tgacaattgt ggggcccata tcaaatgtaa agccgtcttt ctttaattga ttcatacgcc
     4321 cgcctacgtt agtatttttt tcaaatatcg tcacttcatg accttgagaa gcaatacggg
     4381 ctgccgctgc taatcctgtg acacctgcac caattactgc aatcttcatt attcaaccac
     4441 ctatattcta tgatatttac tatttatttc atgaaacaac tttgcttttt tccgcttatc
     4501 cacaaaaaca cgttcatgta atgtatagtt agcctgtctc acttcgtcca gtatttcaat
     4561 atatatacgt gctgctaatt ctatgattgg ttgtgcttca atactaaata ctttgatttg
     4621 atccataaca tctcgaaaat ctttttctgc gatagctgca taatattccc ataagtcaat
     4681 ataatgatta ttaacaccat tttggtacac ttcagcaata tcaacttcat attgctttaa
     4741 tcgttgctta ctaaaatata tccgttcatt ttcaaaatct tcaccgacat ctcttaatat
     4801 attaatcaat tgcaacgatt caccaagcct tcttgcgaca tcgtatgtct gatgtgtttc
     4861 atgatcactt aaaatcggcg tcaatacttc acctactgta ccagcaacac cataacaata
     4921 tccgaataat tcagcgtccg tttcaaacat tgtaaattgt tgatctttat atacagtatc
     4981 aatgagatta tagaaagatt gaaaggcgat atttttatgt tgtgcaacat gctgaagagc
     5041 catcatgatt ctacgatcac tttgaaagtg atgatgttca tatgggtatt tttcaataga
     5101 ttgtatatct tcttttattt gatttaaaaa ttgaatatcg ccataaacat ctatactgtc
     5161 atcaatttta cgacacacag cataaattgc ccaaaccgct tttctttgat cttctggtaa
     5221 caagtcaaaa gcgtaagaaa agctttttga atgtttcttc atgattttat gacaatattt
     5281 aaaattcata gccatcattg tcatactagt cctcctatat tgaaatgcca ttaccttgat
     5341 ttattgttct ttagatatag aatattgacg acctttccat tcaactacac cataacgatg
     5401 cgtttgtttc caagattgga tgaaaatttt agtgaaaaac ataaataaca atggatgaca
     5461 taccattaat aaattagaaa attggccgac ccttcgatgc agatgaataa attgtgtagt
     5521 atagctcaag taaactgtta acatttttcc tacagacatt tggcgatatt ttaaactaag
     5581 acatagccct aaaatactcg cgatagaacc gaacaaccac aacacaattg ctgccatgat
     5641 cttaggcttt gtgccatctg ccccagtcga caaatgcttt gtccatcctt cttgtaatga
     5701 ctgaaatcct tcttgataca tgcgaaatgc aacaaatgga aatccttcat aaactgttac
     5761 gggcaatgat tgtgaagtat atgcacttcc taaagcaaat ccttcaataa tatgacggtt
     5821 cgcactttta tgacctccag ttgcataata atcttcttta tttgttaatg tcaccggtcc
     5881 aaatgcatgc tggttagtcc gaccgtcgtc taaggtagaa aatacattca taccaacgac
     5941 tgtcattaaa ttaaatatcg ctgaaaaccc ttcgtagaaa cgctttgtta tgtgataagg
     6001 ctgtacgctt aacaatcctt tttcatcttg taattgatac tgattaatca acgtttcaac
     6061 agcatctttc cttaagaaag ttacatcagc atctacaaaa gcaatacgat tcgtacatgc
     6121 atgcgtcaca ccttgataac aagcatgtga tttcccatac catttgccgt cagcatcatc
     6181 aacaacatct actacagtcg caccatatga acgcgctaca cgtgctgttt catctgtcga
     6241 tccgtcattc ataacaatga catctactgg aacttgctgt tgtattatcg aatgtagtaa
     6301 atgacctatt cttttttctt cgtttctagc cggaataata attgttaatg atttatgatt
     6361 gaagttcagc gttttcgcct ttagctgatg tctacgatta aatatcaatg caccacacgc
     6421 catagacatg gtcactatta ctgttaatat tcgtgataac catttcatag atatcacttc
     6481 ctattcttcg cttctcgcgc gtttattttg tctgcgactt gttgcccact taatgtaacc
     6541 attggcatgc caccaccagg atttactgat ccacctacaa agtacaagtt ttcaaaatac
     6601 tgactttctt taggaaattt aaatcctttg tttttctttt tatctgctac aacaccatat
     6661 attgcaccac gattagaacg ataatttttt tcaatatcct ccggtgtcca aacatcttca
     6721 taaataatgt gttttcttaa atcagtaagt cccatttttt ctaatttatc caaaatttta
     6781 tccctaaact tcgcataatc ttcagtggta aaaggctgat cttgaatata tggaatatgt
     6841 ggtaagactt tgatattttc ataacctact ggcgcttgtg tgtgatcagt tttattcgta
     6901 tttactagat aaatggtcgg atcatctggc aatacctttt catgaaaaac ttgttgataa
     6961 ttgagataag cattttccgt aaaaaagaaa ttatgatgtg ctaattgcgg gtattggcaa
     7021 gcaacaccta aatgcatcac atatcctgag cttgccggct caaattccct ctctaatttg
     7081 tttaatcgtt gagtatcaag gtgaattaaa tatttataag taggtatgac ttccatattt
     7141 gaaataatat aatctgcctt tacaaactca cctgtatcta atctgacacc cgtcacacgt
     7201 ctttgatatg ttttaatatt gtccacacgt gcacctgtat gaattgtgac accttcttca
     7261 cgcgctagct tttccaaggc attggctaaa tgatggattc caccttctac ataccaaagg
     7321 ccttgctctt gttgcatatg gaataacata gataatacag ctggcgcatc gtatgatgaa
     7381 gaacctacat atttgataaa atagcctaac atttgtcgca agtatggatt cgagatacgc
     7441 ttgtctatgg cctgttgcat agtatgtaca taatcataat taataagagc atttaatggc
     7501 ccatgaaatt taataatttg agatagtgta tctaaaccat agttaaaata ccctttttca
     7561 gtaatacgat cgattcgtct tgtataattc aaataatttt gcagttcctc tatatcctgt
     7621 ttcgacaata tcacattatg ctgacctgtt tctttaatac cttcatacaa atcgatagtc
     7681 gttccatctg gaaaaaagct acgccattga tgtggcaatc gcttgattgt aacgtagtct
     7741 gacatttgct tattgctata ttcgaatatt tttttaaaaa tataaggcat cgttaaaata
     7801 gatggaccta aatcaaagcc aaagccatct gattcatgac gattcacttt gcctcctata
     7861 tgattatttt gttcatataa tgagaccgaa tagccacttt gcgccattcg aattgctgca
     7921 gaaatcccac ctaagccacc accaataacg atgatatgtt tagtcatgac gttcacctct
     7981 tcgttttaat atgcgtagta actgcgttaa tctcggtcga ttataacgtt gcacaataat
     8041 gattggaaca ttagttatca ttgcatagaa aatatttata tactttacta aacgagggcc
     8101 tttattaaat atgatgactg gaagtatcga tatccaatgg atcaactctg ccctctttgt
     8161 ctctataatc attttttcaa tttcatcagt attgattgtc attaaatgac gctgatcata
     8221 tatattttga ttaagctgat gaccatctaa aatcttatgt ttccattttc ttacgtaaaa
     8281 ccatttgttc caaaattttc catgcttctc aaagttaaat gatttaaata ttatatgctt
     8341 ctgacgaaaa tacttgtcag gaattcttgt acctaaattt gctatattta gttgaacaat
     8401 taaccaatac atactacaaa aaaatgctgt tttgatatat tttttcatgg ttttcatcta
     8461 aattgaatca ctctcaatca tactgacata gtataaatta tcattttatt acttagttcc
     8521 ctaaagatta gtgaataaac cgctctcatt tatatttata taaaacaaaa acgccaatac
     8581 tctcatgtta gagaatattg acgtcatttg atttacattt gattaatgaa tgaaattata
     8641 tgaacctgct tggtttgctg aaattgtacg agacgtaacc acaccagcac catgtccata
     8701 gttcatttct gaaacacgaa cagaaccgtt gctgttaacg ccttcaacgt aagcaacatg
     8761 accgtaatag ccttgtgttg tttgcatgat agcaccagct tttggtgtat tgttcactgt
     8821 atagccagat gatgcagctg cgctagccca attacttgcg ttaccccatg ttgaaccaat
     8881 tttcccacca acacgatcaa atacataata agtacattgt cctgaagtat ataagttact
     8941 tcctgatgca taaccattag aaattgaacg accatttgaa gatggcgctg cagttgtagt
     9001 cacatgaaca ttattacttg ttgtgctata acttgcacct gaaccaccag tataatagtt
     9061 atttgttgct gtttggctat tgtttgtata gttattgtat tgatatgaat gattatagta
     9121 gttattgtaa gatgcattgt tataactata cgtattgtag ttattgtaat agtatgtgtt
     9181 gttttgcgtt aattgacttg gattccaatt tcctgtccaa gtgtaatgat aattaccttg
     9241 tgcatcaatt gtatacgtat agctgtatga ttgagcgtca ttagaattat atccattgtt
     9301 attttgttct gcggcttgtg catcatgtcc tgcaaatgcg atagtggcaa gtcctgctgt
     9361 agcgattgta gctgtaacga tttttttcat aattaaatat cctcccaata atcaaaacac
     9421 tctatacata tagtcattag cgactcaatt attttaaatt ttatattttt tattttttta
     9481 gtatgcaaat aattataact tttatagttt tgcgacaaaa taaactataa cagagattag
     9541 gtgtcttgcg ggctttgtta tcataatgta atctgttcct aataaagctt cattgaatgt
     9601 aatataccaa ttagaatgtt tacaacactt tttctgcacc gttaacatgg gatttgaaaa
     9661 taaaaaagca ctaaactttt aatgaaatac acacgaactg acaataaata tcagaagtaa
     9721 tgtaatattt caaaagttta gtgcatcaag ttatttttta tttgtagcat gtgtttccat
     9781 cgtttttaca atcaaatcag tcagcgcttt actacctgca tattccaaat gtatgccgtc
     9841 atatgcaaag tattccggat gacctgcaga agctttatac caatcgacta gatgtacatt
     9901 agagcgcttt tcagctgcct cataaattaa tttatttatt ctaccttcat aatctctagg
     9961 tactctaata gaaactaaat aaatgtctgc ttttccaaaa ctatccaata gttcatttaa
    10021 ttgatctttc gtaaatgccc catttgtacc aagctctact acaacttttt gacctttttt
    10081 agcatagtct ttatattgcg atttcacaat tggtgtagca tcaacgagtt gccgtccaac
    10141 tttaccatca atttgtgcat ttggtatttt cttagtaaag acattaccaa tatccaccat
    10201 gaccgagtca ccaattaata gtggtgatga ctttttaata tcctctttgc tattcgctgt
    10261 ctgcttatcc tcttgcttat cttttttaac gacttttttc ttcgttgttt taaattccgt
    10321 cttcttctct ttcttctcgg cttcatgttg tttgccaagt gcatcaaact gtccactgag
    10381 cacaacgata gacggaacca ataataggat aactaacact gttctagcaa attgcccctt
    10441 ctttttaggt aaaaatgcaa aagctttaaa tcctttttta cgtataggtg tttcaataaa
    10501 gcgatacgaa atttcagcca ttaacgctgt taatacaatt tctatcacat agacgtatac
    10561 aggtatttgt ccttgtacgt aataactgtt cacaaaaaca atgataggat aatgccataa
    10621 atataagcta tatgatcgtt tacctataat tagcaaaggt ttcatactta aaaatttagc
    10681 aaataaacta gaaggatgta ccgcaattgc aataatgaat aaagttgcaa atgatataat
    10741 gtaaaatcct ccattataga tccattgatc ttggtctcca actataaaga acaaagtcat
    10801 tagaaccgca aaaccagata tccctataat atctaatgat acgacaatct ttttagaaat
    10861 atcttttttc aaagcaaacg gaggccaaat aaatgctaat atacaaccaa gcaataaagt
    10921 ttgcagtcgt gtatctgtcc caaaatacac acgtgaatta tctccagtga tgaaatgaat
    10981 cactatcata agtcctaaag aaatcaacga tacaataaat agcgtttgaa taatatttct
    11041 cggtttaaat ctatgtaata agaacgtgat aaccaatggg aaaagcaagt aaaattgttc
    11101 ttcaatggct aaagaccata aatgtttgag tggttcaata gcaaattggt taaaataatc
    11161 tacattctgt gaaatgtacc accagtttga aacatagaat atagctgcaa tagcatctcg
    11221 tttcatttgt ataatcaatt ccggtttaaa tatcagtgtg aacgtaagca cgacacagat
    11281 taaaaacaac actgccggaa tgagtcgttt caatcgtcgc ttccaaaact ctagcaaatc
    11341 gattttttgc gtccgataat actcacttat caacaaactt gttattaaat aacctgaaat
    11401 aacgaagaat gtatctactc ctaaaaagcc cccacttaac cattgtgcat tcaagtgata
    11461 aataatgatt cctataactg cgaatgccct caatccatct aatccgggta agtatcgcgg
    11521 ggaatacatt ttttctaaac gtttaaagtc ttttgtatcc atgttaataa acgccccatt
    11581 tatttttctc tattttgtag catatcacaa tatttttgaa aataaaatat tgcactgatt
    11641 ttcattaatt gatttaaccc ttaattaaga tagttttaaa ttttttatta agtagaaaac
    11701 aattattaca gttaatttca ttactgcaaa ccacatataa atttgtcgat tttactacat
    11761 aacatagatt atcatagatt cttgaatttt taacaaaata actgttgttt tcattatatt
    11821 tttacaaaaa aaggttcgtt ttatatttta tgcatcttac ttttacacaa ttatttaaat
    11881 atacccttta aatttcattt tttcaaaact tctataatga ataaattacc atgtattgaa
    11941 aataaagtga aatgcataat atcctctaat ttaaatcaaa cgatatatca cgtcagcctt
    12001 ttatatttaa acgctatatg ccacttttaa aatgaatatt actaaggtcg ccatatcaat
    12061 tattcattga ttcgaattaa ccttttaaat ttctgtaata aaacctatta tctacatcta
    12121 atttaggaaa actacttggt aaatctcctc gcttaatttc acggaagcca ttattagaat
    12181 aaaaatactg tgcactaata aatttatcaa ttgttcctaa ataaatacca tcgatatttt
    12241 gttctttaca tgtcattata actttatcta aaagtttttt acctattttt aaattcctat
    12301 aaccttcatc aacaaacatt tttttaagtg cagacatatt attatctagt ctaatcaaac
    12361 ctatagtacc aacaatattt tgatgattgt ttattgcaag ccaaaattgc cctccactat
    12421 tcaaatagtt atgttcgatg ttctccaaat caggttgatc atctctatca atttttatat
    12481 taaattcatt tttttgaatc gataaaataa actcgattag ctcttcctta taagacctat
    12541 tatattcaat tatgtttata gtcattttta tctccagttt catttaattt aatcataaaa
    12601 tgtgcgttta gtttgtatct agtgtactca gtacagcctc aaatgaagtt tcattccact
    12661 tggcacttaa taaagacaag tattttagca gtaatacaat aaagtccaat aaagtccaat
    12721 aaatttccct aacttcaata tccacttttt aagaaatgta tttttgatta ataaaaaaac
    12781 tctccccaat ttctatggga agagctatat atttaatgtt taaacattac ttttatttat
    12841 tatgaaggaa ttagaatccc caagcaccta aaccttgtgc tttgtatgct ttaacagctg
    12901 cgttgatttg ttggtcaaca gtgtttgttg gaccccaacc tggcatagtt tggaataaac
    12961 ctgaagcacc tgatgggttg taagcattta cttgaccatt tgattcacga gcgatgattg
    13021 cagcccatgt agaagctgaa acaccagtac gttgagccat gatttgagct gctgatgaac
    13081 cagtagcacc tgcagtatta ccattgctta atctcactga acttgaagta gttgaagtgc
    13141 tgtagttatg gtaagttgga gctgaaacag cttcaacgtt tgagttactt gattgtgcat
    13201 tgtagcttac tgattgtaca tttgaacctt ggttgtatga agtagtgtag tctgcacctg
    13261 caacgtttga gaaaccagca gtttgaccat tagctgcttc atagctccat gaccatgtag
    13321 taccatttga agtgaagtta tattggaaac catcttttac aaagtggatg tcatatgcac
    13381 catctttgat tggagctgca tttaattgat cttggtgatt atgcgctaag tcaactaagt
    13441 gtgcttgatc aacgtttact tcagcagcgt gtgcttcatg tcctgtgctt gctgcgtaac
    13501 ctgttacacc taatgccact gctaatgatg atgccataat tgtctttttc atagtaaaaa
    13561 atcctccagt aataattgta agtttatgtt tttagtaatt atattttgaa tttgaatgtc
    13621 gtagtgcaag tttaaattgt cttttatttc tttcaacggt actcactata tcataaaaaa
    13681 gtagcaagta aattacactt tctttacaaa acattacaat atcaagtgtt atttgtaatg
    13741 ttgaaatatg gttgttttat actgtaatgt gaaatatgtt tctttttgaa tctaatcaat
    13801 ccttgaaata agcataaatg cataagtttt ttactatatt tagctcaact attacagctt
    13861 tcgtaatatt acagattgta tttttgttac atgcttgtaa cattaccgtc atcaaataca
    13921 acttaatttg atcagttaaa cacaattaaa aagcaatcaa tacataggtt ccatcacatg
    13981 tattgattgc tattaatatt aaatattcaa agtgactatg cacatatctt ttgtggattg
    14041 acttatcttt tattagcgca aattatctgc tgttcaatta tattgttcaa cttcattctc
    14101 gcaattcaca ataacattaa ataattttcg gtctcatatt ttcaaaaaac atactgtcct
    14161 tatcccatga atttaaaaat atcattagta tataaacgaa acactttacg ataaatgata
    14221 tctgcaagcc aagctgttac aaatggtaca acaaagaacg ctactacaat tagtaagaca
    14281 ctcaaccaag cagaatcaac ctccataaat ttaaatgcat taatcggtcc taccatccct
    14341 ataaaaccaa atccagctga ttctttcgtt ccatgaatac ctactaatgc tgataccaaa
    14401 cctgatacaa tggctgttgt caatattggt aacataagaa ttggatattt caccatatta
    14461 ggtatcatca ttttaacgcc tccaaagaag acggataacg gcacccctaa acgattcact
    14521 ttacttgtac caattatcaa tactgcttca gtcgcggaga taccaattga cgctgatcca
    14581 gctgctaaac ctgtaatacc tatcgcaaag gcaatggcca cagttgatag tggagaaata
    14641 ataataagac taaataccat tgaaatcaaa atactcatga caatcggttg taattctgta
    14701 aaaccattaa ccatattacc gatggctgtt gtaatcattt tcgtatacgg caatattaaa
    14761 acaccaattg cacctgaaat accgccaaca actgttggga atacaatcaa tgccatacta
    14821 cctacgcgat gttgaataag taaaatgaac aacactgcaa tcgctgctgt aatcattgta
    14881 ttaattaaat caccaatacc cgtaatcatc caagcaccat ttttaaactg cgctgcaccg
    14941 cttcctacat atgctgcact cgccacaaca gcaattgcta atggtgatag gtcaaatttc
    15001 atggcaacca atgcaccaat caaagcaggt actgtaaatt gaattgcaac gacaacgcct
    15061 aataacgttt taaaaatcgg atgataatcc ataaagtatt taaaaatttc tccaagtatc
    15121 gcattaggaa ctaaacccgc aacaatacct atggcgacac ctgataaaac tctaaatata
    15181 aaatctttgg gtgtaattgt tttaattgat gtcataatat catccttcca tttatgtata
    15241 tacatctgta tgcaaataat aaagagcctt aagttataag ctgccactag cttaaattct
    15301 aagatgtgca tgccgatgtt gttatattta ggctagcagt atcatctata actcaagact
    15361 atgaaaaata gtatatcaca aaattctgaa tttttagata aagaaattgg caatttttca
    15421 aacatattgt tacaatacac ttttatttta tcttcatttt taaaatccat taatacaata
    15481 gaagaaagac attcaaatgc ttaccaaaaa ggtacattat ttgttaggag cgtatcagca
    15541 cttacatatc atcaacacaa ttgacaatat aatagaagat actgataata agtgttaaaa
    15601 caacagatgt taggtagtga acaaacgatg gaaagtaaat ccatagatcc aagaatcgtt
    15661 agaaccaaac aattgcttgt cgatgctttt cttaaaattt ctagagaaaa gaaattatct
    15721 caaattacag ttaaagatat cactgatatt gctacgctaa atcgtgcaac attttacgct
    15781 catttcactg ataaagaaga cctcctagac tacacattgt ctgtaaccat tttaaaagac
    15841 ttgaatgata acttgagcat ttctaatgtc attaatgaaa aggtactgcg taatattttc
    15901 atttcaattg cgagttatat caaagatgct gcaaagtctt gcgaattaaa tagtgaagca
    15961 ttttgcaaca aagcacatca acgtattaat aatgaattag aagatatttt tgcgattatg
    16021 ttagaaaaca gctacccaga gcatcaacgc gatatcattg taaatagtgc gagtttttta
    16081 gcagctggta tctcaggctt agcattacat tggtttaaca cgagtcaaga gacagccgat
    16141 gtgtttatcg atcgcaacct accattttta attcatcata tagcacattt ttaataaaac
    16201 ttagtattta gtcatgcatc ttgaaatcac tatgtgactt aggttcatac ttgtacacac
    16261 aataaaattt aacgtattac gattaatttg cagtgtctag gacataaatc aacgtcctat
    16321 actctacaaa gccatattgg cagtcgttaa ctgaatgaaa ataagcttgt cattaaaaca
    16381 tatagatttt agtgacaagc atttttgttt ttgcgtactt aaacaacact tcagacaata
    16441 tgttgtttag gcaacaaatg atatatgcgt gtttattggc aaacgtacga catagtagta
    16501 tagtatgtct aaacaacaca tgtcgtatag ttgatatacg ttgtttaaat actaagatag
    16561 gagggattga cgtgagcgag acagatgaat ctcaggggtt tgaacgcacg cataatatat
    16621 taaatattaa tcagagtagt ctgggtgtag tgacatacat tacaaataaa ttaaagtcga
    16681 cgttgaagca acacataata attgcttgtg gtaaaaagcg aatcgactat cgactgtcgt
    16741 ataactttta cactacgtat tatgataatg tagaaatcaa gaaaatcaac tgtgaatata
    16801 cctatgctat gcccattgca attttaataa gacacatgat gtcattcgac aatgattatt
    16861 tctttgctca gctacgtcat cctgtcttat aaaacaacat tgcagacatg tatatcaaac
    16921 gacacttcaa taacatcagt ttgccatcgt actactatta aaatcgtgtc tcaaacccct
    16981 tattttaatt ccaaaaatct gctggtcaaa agaccgagaa actaaaaaca ttactgaatg
    17041 tgttgataaa ttaccttata gaaataatct caaaatatat caacacttga ttctaaggag
    17101 gatatgacaa tatgaaaatt ttagatagaa ttaatgaact tgcaaataaa gaaaaagtac
    17161 aaccacttac tgtagctgaa aaacaagaac aacatgcatt gcgtcaagac tacttaagca
    17221 tgatccgagg acaagtatta acaacatttt ccacaataaa agtggttgat ccaatcggtc
    17281 aagatgtcac accagataaa gtttatgatc ttcgccaaca atacggttat attcaaaatt
    17341 aatatttgct cacgaggtat tgcacttaag gtgccaactg acctcataaa caaagcccat
    17401 actgattgaa gacactaatg tgtccaggct gggacataaa tcaatgttct atgctctacg
    17461 aagttatatt ggcagtagtt gactgaacga aaatgcgctt gtaacaagct tttttcaatt
    17521 ctagtcaggg gccccaacaa agagaatttc gaaaagaaat tctacaggca atgcaagttg
    17581 gggatgggcc ccaacaaaga gaaattggat tcccaatttc tacagacaat gcaagttggg
    17641 gtgggacgac gaaataaatt ttgcgaaaat atcatttctg tcccactccc acattaaact
    17701 tcatctctgt atgggctttt tatttattct tttgagaatt tcattttagc agaccaaaaa
    17761 attaaaatgg tgtccatcaa gatctttgaa cattgcacca taaaaccctt ggcttactgt
    17821 tggttcttga acgactgtgc cacctgcttc tttcacttta ttcaccaact ggtcaacttc
    17881 ttcatttgtg ttcacaccta gagaaatcat cacttcattt ggttcagtat taaggctttg
    17941 ctgacttaca ttttgaaaat gcttgttttc tattaaaatt acggttgttt gacctatttg
    18001 aatgcccacc attttatcta acatttgtgg gtttctattt attttaaatc ctaacgcttt
    18061 ataaaactgt gcgctctttt ctaaatcttg aacatgcaaa ttaaaccaca ttgattgaat
    18121 catgattgca ccccattcat tacttattat agtcttggac tttaagccaa tcacttaatg
    18181 ataatcttgt tggatttatt tcagccatta attcaaagtc tacttcataa cctttttctt
    18241 ccaaccattg cttttctgca acactactaa caaattctcc ttcaataaca gtcgatttac
    18301 ctgtcacttc actaaaaatt gttgctgctt cacttaatgt aacttcatcg gaaccaatct
    18361 ctattgattg atgcgtaaag ctttgtggat gtgcaaaaat atacgatgca attttagcta
    18421 tatcaataga agaaatcatt gtgaatttta tattcggatt aataaattct ggtaatgtaa
    18481 tacgttcatc ttcgacttta gcaatgcgta aaaaattatc cataaagaat gatggtttga
    18541 taactgttgc gtttatatta gattccatta atctattttc tatttttgct agtacttcaa
    18601 agtgtgggcc agttcgattt cgattaaccc ctcccgcagt actatacaca atatgttgaa
    18661 tattttcttg ctcagctatt tcaattatct tcataccttg tcttaattct tcgctaacat
    18721 catctttaac gattggctga atactgtata agccatactt ccctttcatc gctgattgca
    18781 aactatcact atcactcaga tcaccttcaa cgattgataa atgcggatgt cctatgtctg
    18841 aaagtttacg attattctta tttctagtta atgcacttac ataccatcca tcctctaaca
    18901 actgttttac aactgcatta ccttgcttcc ctgttgcgcc tattactaaa atatctttca
    18961 ttttagatcc actccccttt tatcttaaaa accaatagtc ctctttttca ccttttaaat
    19021 acgtatatgg ttctggtgtt tgtccatttt ccttaatatt gtcatttatt acatttctga
    19081 catcccatac taaatgaata aatcgttgta attgatgact aaaaatgcct agtggcgctt
    19141 tcatagctaa tgctttttcc acatcttctg tggtaacatt cagtttttct gcaatcattt
    19201 gaaccgataa agttgatgct tcgaaatgtg cttgcaattc ttcagctgta atacgtcttt
    19261 gctctttatt taaagacata cgcaacactc ttttctttta tgatatttaa tagttattgc
    19321 aaattcattg ctatctttct taacacgctt tataataaac ggagagttat ccgtttgtca
    19381 attttagaga attttaagta ggtgtaatca tgcgaaaaga tgcaaaagag aataggcaac
    19441 gaattgaaga aatagcacac aaactttttg atgaagaagg cgttgaaaac attagtatga
    19501 atcgtattgc taaagaacta ggtatcggta tggggacatt gtatcgacat ttcaaagata
    19561 aaagcgattt atgctactac gtcatacaaa gagaccttga tattttcatc actcatttta
    19621 agcaaattaa agatgactat cattctgatt atgaggttat gcaagtgtcg ttagattatc
    19681 ttttacaatt taaaatcgat aataaggcac tactgcaatg tattgaagca ggcaacaata
    19741 aattacgttt ttaccaaagc gcattttatc aagaattatt taatttttat tatgacttat
    19801 ttaaaagcga tgacgacatt tacaagaagt tcaaaacaga tatgctgttg caagcattat
    19861 caactagtgt atttgccttc caaatagagc atcgccatat ttcaattgaa gcgtacagaa
    19921 attatttatt aaacatttat ttagatgagg tggaacgtaa tgactaaaat tgtgttaatc
    19981 acaggaggca ataaagggtt aggctatgca agtgcagagg cacttaaagc attgggttac
    20041 aaagtttata taggttctcg taatgacgta agaggacaac aagcatcaca aaaattaggt
    20101 gttcattatg tacagttaga tgttacaagt gactactcag tcaaaaatgc ttataacatg
    20161 attgctgaaa aagaaggccg tcttgatatc ctcattaaca atgcaggtat atctggtcaa
    20221 ttttcagcac cttccaaatt gacacctcgt gacgttgaag aagtatatca aacgaatgta
    20281 tttggtatcg ttcgaatgat gaacacattc gtccctctct tagaaaaatc tgaacaacct
    20341 gttgtcgtca acgtatcaag tggtttaggt tcatttggaa tggttacaaa ccccgaaaca
    20401 gctgaatcta aagtgaattc attagcttat tgttcgtcta aatcggcagt aacaatgcta
    20461 acgctacaat acgctaaagg attacctaac atgcaaatca atgctgctga tccaggcgct
    20521 acaaatactg atttagttgg tgattttagc aataattcaa aacatgtttc tgaagggatc
    20581 aagccaatca ttcaattagc aaccattgat gcagatggtc caacaggtac atttattaat
    20641 ggcgatggag agatgccttg gtagatcaat tttatgttac aaatattaaa tttagaggta
    20701 aataaagaat gcttctgcaa tagatgcaat atacatgcaa aaaaatatgg aggcgaatta
    20761 aatgaaaagt attacgtttg aagaacatta tgtcattgaa gatattcaaa aagaaacgat
    20821 gaatgcgata tcagcagatc ctaaaggtgt accgatgaaa gtaatgttag aaggccttga
    20881 aaaaaagacc ggttttacaa atgccgacga attatcacat catgatgaac gtatccaatt
    20941 tatgaataat caagacgttc aaattcaagt cttatcttat ggaaatgggt ctccttcaaa
    21001 tttagttggt cagaaagcca ttgaattatg tcaaaaagca aatgatcaat tggcaaatta
    21061 tattgcacaa tatcccaatc gctttgtagg ctttgcaact ttacctatca atgagcctga
    21121 agccgcagcg cgagaattcg aacgttgcat caatgattta ggattcaaag gtgcgctcat
    21181 tatgggacgt gcacaagatg gttttcttga tcaagacaaa tatgacatta ttttcaaaac
    21241 agctgaaaat ttagacgtac cgatttatct acatcccgcg ccagttaaca gtgacattta
    21301 tcaatcatac tataaaggaa attatcctga agtaactgcg gcaacatttg cttgttttgg
    21361 ttatggttgg cacattgatg tcggtattca tgcaatacat cttgtattat ctggcatttt
    21421 tgatcgttat ccaaagttaa atatgattat tggacattgg ggtgagttta tccccttctt
    21481 cttagaacgt atggatgaag ctttattcgc tgaacatttg aaccaccctg taagctatta
    21541 ctttaaaaat aatttttata tcacaccgag tggcatgtta acgaagccac agtttgattt
    21601 agtcaagaaa gaagtaggta ttgatagaat tctttatgct gctgattatc catatattga
    21661 gcctgaaaaa ttaggtgtat ttttagatga actgggttta acagatgaag aaaaagagaa
    21721 aataagttat acaaatggtg ctaaattatt aggtttatca tctaacaatt aacaaatgga
    21781 ggtcattgaa tatggaaact ttagaattac aaggcgctaa attacgatac caccaagtcg
    21841 gacaaggacc cgtgctcatc tttattcctg gtgcaaacgg taccggagac atttttctgc
    21901 ctcttgcaga acagttaaaa gaccatttta ctgttgtagc cgttgatcgt cgtgattatg
    21961 gagaaagcga gttaactgaa ccacttcctg attccgcttc taaccctgac agtgattatc
    22021 gtgtcaaacg cgacgcacag gacattgccg aacttgcaaa gtcattaagt gatgaacctg
    22081 tctatatatt aggttcaagt tcaggttcaa tcgttgcgat gcatgtgtta aaagattacc
    22141 ctgaagtcgt taaaaagatt gcatttcacg aaccaccaat taatacattt ttaccagaca
    22201 gtacttattg gaaagataaa aatgatgaca ttgtgcatca aattttaaca gaaggcttag
    22261 aaaaaggcat gaaaacattt ggtgaaacat taaatatcgc accaattgat gcaaaaatga
    22321 tgtctcaacc tgctgatact gaagaaggac gtatagaaca gtacaaacgt acgatgttct
    22381 ggtcagaatt tgaaattaga caatatacgc attcagatat tactttggat gatttcacaa
    22441 aatacaacga taaaatcacc ctactaaatg ggacagattc tagaggctcc ttcccacaag
    22501 atgttaactt ttatataaat aacgaaactg gcatacctat tgtagatatt ccaggtggtc
    22561 acttaggtta tattcaaaaa cctgaaggct ttgctgatgt attattaaat atgtggagtt
    22621 aattgatttt atagctttat acaactgcac catgctgaaa agttacattt ataaattgat
    22681 aatatactta tagagtgaaa tatttgtggg gtctaatgaa aatattgtaa tgcattttaa
    22741 tcactgagga gccatatata ctatgaaagc cattcaaata aagaaataca ataaaaatag
    22801 agatgtacaa attagagata ttactattcc agagatcaaa tctactgagg tacttgtaaa
    22861 agtagcttat gcagcaatta atccattaga aaatttaact attaatggaa gtgtcaaatt
    22921 aattcaaaac tataaaatgc ctcaaactat tggtaatgaa ctcacaggaa caattgttaa
    22981 agtaggaagt aaagtcgaag attataaatt aggcgataaa atatattcac gattaccaat
    23041 cgatcgtata ggtgcttttg cagagtatgt ttctattgaa tctaatgcta ttgcaaaatt
    23101 acctaaaaat ttaaacctta aaacaggtgc agcagtgccg ttaacaggtt taactgctta
    23161 tcaagcaatt actgaagaat taaaagctat acctggtaaa acattgttta tacctggtgg
    23221 ttcaggcagc tttggacaaa tggcagtacc tatagcaaaa tcattagggc ttaaagttat
    23281 tgtatccgga agtccgagac ttaaagatca atttttagct aagggtgtcg atcaatatat
    23341 agactacaaa actgagaatt actgtgaagt tttatctgac attgattatg ttatagacac
    23401 acttggacca aatgaattcg ataaagaatt atcagttatg aaacctggtg gtactattgt
    23461 cagtcttatt aatgcgccta acaaagcatt tgctgtgaaa aataattttt caccatttaa
    23521 aaaattgcta tttggtttag caggtaaaaa attcgataaa aaagctcaaa aaaagtcgat
    23581 agattatcgt tttatatttg tacgttcgga tggtgagcaa ttaaaaattt taaataaaat
    23641 catcgaacaa aacaatatca taccagacat cgacgaccat attttcacaa tagacgaaat
    23701 tgacaaagca cttgactata catttaatca tcatacaaat ggcaaggtat taatacgtat
    23761 tgataactct gacaacacaa tttattgatt aaatagatag tacctgaatt tatcttatat
    23821 ttatttgtag ctttaaaaat aatatcaatt attatctttg accttatgga tactattaat
    23881 agatctgtat ttaacaataa agaaatatac ctaataaaat aatttataaa tgcccctctc
    23941 actacaattt atataacaag tggggcattt attatctata tactgttcat tctttcccac
    24001 tgaaaacact actgttccaa acattgatag tcttcttttg aaataccctt tccgataagc
    24061 accaaatatt ctggcacttt ttttgaaaat gctacaggtg ttaattcata ttgtccttgt
    24121 gtaaattgaa tgagatacgt atgtgcggtg tcttcaaatg tcataaaccc tttcaaccta
    24181 taaatatgag acggaaggca tgctaaacgt tttataaact ctgctttagt acatttgact
    24241 ggtgattgca caaattgatg atttattgtt ttgtgtaatg attcatgttt attgtcggaa
    24301 gtaactgtca tttgtctaac tgatattggt aaagtgacgc tgccatgcat accgacttgt
    24361 atatctgcct ctgggttaat aacttctaaa tctttcaata gtttgctcgt tgtttcaaca
    24421 tctgctgaat ctattttatt aacaaataag acagaacaat atgctaattg ctcataaaat
    24481 aagccttgga tgtcttttgg aaatgatttt atatgtttat acatgcttgc atctacaaca
    24541 ccaatcatat gtgtaatggt tgtaaacgga gctaaaatag gcgttaaaca agcatctaag
    24601 acagagaccg gttctgcaat cccactacat tcaataaata caatgtctgg ttgctctttt
    24661 aaatataatt gatgtaattg ttctgataca tctgctttca ttgcacaaca gatacacccc
    24721 tctgtcagtt cacttaaagg tatgtcttca gatactaagg caccatcaac actcatttta
    24781 ccaaattcat tcatgataac tgccggtttc agcgactcct ttaatgattc agcgagcaaa
    24841 tgatttaaga cagtcgtttt accgccacct aaaaacccac ctataataac tattttcatc
    24901 tgcgactctc ctcttatact tcatatgaat agcatattcc aagatatctt tcctattgac
    24961 tgacatgact ctatattcag ttatagttca tttctttttt aaataatcag cattactatt
    25021 ttaacaatga tgcctacacc aataactaaa gacaatgatg tcaacatttg ctttccaatt
    25081 aattttagtg ctgactgacc acctaaatgt ttcaaaagca tcgtcattgt gaccgagcac
    25141 gctgtaaatg ttgaactaaa aaacacaagt agtagtaact gtgttgctgt cattccttgt
    25201 aataaggcgc cttgatgcaa attaaacaag agcatgccgt cttttcgaat cattgaaaat
    25261 aaaatccctg gtgacaattc tgacgagatg cctaataacg ataatatagg tgtaaatatt
    25321 tgtgataaaa cattcaaaat tggcgttagt gataaaatac taacaataag acagattgtg
    25381 ataaaaatag gtagcgcttg aacgataaac atttgtatat tttgccacat ttgtagcaac
    25441 atttgacgta tatttggcat atgtaattgt ctatcataag gtagcggaac gctaagttgt
    25501 tgattattct ttttcaacca tatcctatta tgtaagatgc cacctaaaag tactaatatt
    25561 aagtacggca taaatagcca tgactttcca gctacactaa aaatagataa tgtcgcacct
    25621 atttgataac tacaagaact accaaagctt attaaactca tacactgtgt cttcgtgcag
    25681 gtatggcatt ggtgtgctgc ttgtgaaatg gcggctgcat tacatccaaa tccttctaat
    25741 agtggcacga tatcattgcc ttgtaatcct atccgtaaca ttgacggttc aattgcccat
    25801 atcatccatg atttgaatcc tgtttgatca attatagcag ttgataaact aatcaatatt
    25861 acaaccggca atgcccatac gagcgaatat gttccaagtg atagcacacc ataatcacca
    25921 aataatatat gctgtaatat atcgtgattg agcaatgttg tttgagttaa atattctatc
    25981 catgctgata catactgatt ttgaaaccaa tctgaaaatt gataagcaat accaattggc
    26041 aatgcaaaca ttaaaaatat caacaaccag gctaaaaatg tcgcacttat tttaggtctt
    26101 aaatgtcgtc gctcatgttg aaatagtgtc aattgttcta tcacatgttc gctcgctata
    26161 ggcgaagaaa ctacactttc tgccaatgaa atatctaatt tctgttttat gattaataat
    26221 cttaatttcg ctttttctgt tgcgttaagt ttatccgcat gactaataac caaataatga
    26281 ggttcattag gtatgggcgt ataatgccca gttctcatat catatttcac ttctaacatg
    26341 tgcatgacac ttcacaacat gaataatcat ctaaatacat ttgatttttt tggtaacttt
    26401 caatgacatc ttgtttagct ggtaagcctt cccgctgtgt taaaagatgt gcaagtactg
    26461 caaatcgcgc tctaaattta tagatatagc ataatttggc attatcattt tcaactgttg
    26521 caccaatcat aaaaatattc ggataacgtg tcgattcatc atgtgttgtt aatttaatat
    26581 cttgatttgt tgtcgcaaat aattgttgaa cgattggatt ttttgttgca tcaaagccag
    26641 ttgctagtat tggttcatga ggcgtaagca cactttgtcc gctatcaaaa ctgatatgat
    26701 actgtccgtt gttaaaatca atatctttaa ctgtataatg tacattcatt tcaatacgag
    26761 caccttgttt aatgacatta cctagtcgct gacgtgtata aggtgacaat ctaacactag
    26821 gatcagcatc cggatcattt aaaccggttg tgctagtata aagtgcgatg tcagagccat
    26881 tttttgcaag ttgatatgca gcatcaaagc cactttcatt acctccgata accacatatt
    26941 gccccttatt aaagttatca aagtcttcaa tttcactata atgaatacca tatttaaatg
    27001 gctttttagg gaaattataa tcacctgttg cgacaaagat ataatccgcg tgatatgtct
    27061 ctgttgtcgt tgcaatcgta taatatgcat catctacaga tatatttgta acaactgtat
    27121 tttcaaagat attcagctcg taatggttgg caaccacttg taaatattca gcatatgttt
    27181 ctccggaaat atgttcttca ttaaatgtaa atgctggtga agtatccata gaaattgcat
    27241 tcatatcagg catgccaaat ccattagacg taaatgatgg cgtaatcgta cgggtcgatt
    27301 tcggccaatg tttaaatgaa tggcctactg ttcctttttc taaaataatg acatctgtta
    27361 taccgaaatc ttttaaggta atggccatac ctatacctgc agcaccggca ccgataatag
    27421 ccactttatg atgttgcata ttaacactcc ctcaatgatc tatttcaagt tattgttcct
    27481 gactataaat cgtaataatt acgatttata aagtatagac ctatccttga gaaatttcaa
    27541 tattaaaaga aaaacttccg ttattgtaga gaattcatct acatttcgga agttggtatg
    27601 tgtctttttt attaaattta aagatgctac ggttagttca aatgattatg aatgacattt
    27661 aatggtatca tccaacctca gtacttggat ataacatttt ggcggtgaga cagaaatcat
    27721 atttttacaa aatttatttc gtcgtcccac cccaataaag aaaaagtatt tctttattgt
    27781 tgtgtaactt ttccacgttg tatttcacta tccaaatttt gtttcatatt atcaaacaac
    27841 tcttgaaatc taacctcatc ttgatcagaa taacctttaa aaataactga atctatattt
    27901 tcctcgttaa aataataaat ttcatcttcc acaacaccaa tcggatattt acatccagaa
    27961 tagtcaaaca tatacttttg attttcaatt tctacaattg gtcctctatt aataatcatt
    28021 aacttttgcg aaccttcttt taaataaata atgcttccta ttgtttccat ttattttcct
    28081 cctttgtcac cgtctcaatt tcaacattcc ttcgcatttc caagtcaatc atctcttctt
    28141 ccgctttacg aatgccatgt tgaatttgct gttgctgctc gtgtaacgct accgttgaac
    28201 gtcgtttcgc aaaatgaaat tcatcgcgga actgttccat acgactagcc atattgctac
    28261 tataataacg ctcacctaaa tgttgatata attgatctat cgaatgatta agcgcatcac
    28321 tttcatctat caatgcttta acctctcgct tttcatcata taagtcatcc atttgctcat
    28381 gtttcgctgt gattatttta ttgatttcat ccagtttatt cgacatcatt tcaccacgtt
    28441 ttaattttta ccaatttcat taccaatcat tacgtcagtt tggtcaaaag cctcaccaac
    28501 tttttgtata ttatcgctcg cagttcgtat tgcttcagca acagattgat tcttactcat
    28561 caaatcatct atcacactat gagcattatt atttccactt actgttgtac tttcatcttt
    28621 atccggtttc gacacattat tacatgtttc aacagcgctt ttaatagatg atgatgcact
    28681 attggtctta aaaatatcac tttgaactgt actcatcatt tacacctctt cccatttaaa
    28741 ttattttaaa attattagaa actgtatcaa tatatgatat tcaaacattc aataatactt
    28801 aaatattgtt ttgtgattat attcaaaatt attgtatcaa taaatatgta tcattcctag
    28861 aattttatta aacaaaaagt tagaaaatca cttttattgc aactcaatct tgttttgcat
    28921 tatagaaatt aacaatagag attaaaattt tattttccaa caataaaaaa gcacaaatat
    28981 ttttattgag gcagctgaag gccttctcat tgtaaaaata tctgtgcata ttattatctt
    29041 aatctaacgt aataactaac ctgttgtatc ttgtaaaatc ttatccatag agtgcgcaac
    29101 actatcacgg tacatctccc caaatttcaa taaatgcacc atcaataaat ataaacgata
    29161 aaattcaagt ctataggatg caccttttgc aagtggataa tgtttattat acgcatcata
    29221 aaattcgctc gtaaaaccac caaataccgt tgtaataccg atatcaaatt ctctgtcacc
    29281 atataatggt gctggatcaa ataacgccgg acgaccatct tgtaagaaca tataattgcc
    29341 accccatagg tcaccatgta ataaagacgg tttactttga tgcttttcta attccgccac
    29401 aatttgacgt cgcactttgt catatacttt gatatcgttg gcatcccata gccctctatt
    29461 tagcaactca tctttcaaat gatccatgcg cttgtcgaca aaaatggtac accaatcgtc
    29521 ttgccaatga ttatcaaaag aaatatcgcc accttcataa ggtaatgaga agccaaattt
    29581 gccttcttct tgttgctgac tgtgtaattg agctacgagt tgccctaatt ggcgttgact
    29641 ccctgaagcc ccttcttcta aatacgtcat cactaaatac gcatcaccgt taacctcgcc
    29701 acttgcaatt actctaggtg ccgtgatacc tgcacgttca aattcattta aacctgcaat
    29761 ttctgcagca taaaatgatt ctttacgtcc acgttggaca agtaagaaaa atgtatccgt
    29821 atccgtttcg actcgatatg cttcgtttac atcgccacca ctcactggtg aaatctcttt
    29881 aatatctttt aaaggtaaat gctctaacca ttgttcattc atacaaacac cttccattac
    29941 gcttacttta tactattata ttgcctaatt aagatgattt aatctcaatt ttatttgtgg
    30001 tacttgcgtc aattttcaaa actttttagt tttaactagg aaattatgta gggaaatgct
    30061 agtctattaa aagaatatat ttcacatata ttaagttgag gatagtaagc ctcaaatata
    30121 atgaaatagg agcatactca tgtacaaatt aattaaacct ttcttattca aaatcgaacc
    30181 cgaaaaagca cacggactaa ctatcgatgc attaaaaacg ttacaaaaat ttccggtttt
    30241 attcccagtc gtcgataaac tatttactta taagaatcca acgttatcac aaacgataca
    30301 aggtaatacg tacgacaatc caattggctt agcagctggt ttcgacaaat cttgcgaagt
    30361 accaaaagca ttggaacacc ttggattcgg tgctttagaa ttaggtggta tcacacctaa
    30421 acctcaaccg ggtaaccctc aaccacgcat gttcagatta ttagaagatg atgccttgat
    30481 aaatcgtatg ggcttcaata atattggtat gaacaaagca ctcagtcatt tgcgtaaaaa
    30541 tgcttatcaa gtacctgttg gtatcaatgt tggtgtgaat aaaatgacac cttatgaagc
    30601 gcgttatcaa gattatataa aagtcattga tacgtttaaa cacgacgttt catttttcac
    30661 agtcaatatc agttctccaa atactgaaaa tcttcaaaac ttccatgata aagatgaatt
    30721 ttcaatgtta tgccaagctt taacagcatt taaaaaacaa catgatgtaa cagtgccaat
    30781 ttatttaaaa ctaacgtctg atatggattt cgatggctta aaagcactat taccagcgat
    30841 tactgagaca tttgacggta tcatcttagc aaacacaacg cgacaacgag atggtttaac
    30901 ttctgctaat aaagtcgaag aaggcggttt gagtggtcgt tcattatttg aacgtaattt
    30961 aaaattgatt aagtatgctt atcagcaaac aaatggtgaa tttttaatta taggtacagg
    31021 cggcgtattc agtactgaag atgcaatcaa aatgatgcgt cacggtgcgt cacttattca
    31081 aatttattca tcacttgtta ttgaaggccc aggtttaact aagaaaatga acaaaggcat
    31141 cgcacgttac ttaaaagatc atcattttga caatgtcagt gatattatag gactagatgc
    31201 ctaatccaac gtagtcaaat aatactttaa aacttgctga atcgtcttat taaaattatg
    31261 atataactca agaagatata tttatcacca tttttcaaaa taatggctta aatatcacat
    31321 atcattaaat atagcgtttt ataacggagg cgtttgttat gactaaagaa acagataata
    31381 aaaaaacagt agcgacttct gacaacaaag acacacagca acaaaatcaa cctgaagaag
    31441 atgaacgtca aggtttgaat ggttatcgta aaacagatct tgatttagaa attgagcaag
    31501 agctacgtga aatgatgaaa acaggagaaa atgaaacgaa aaatgactac aaaaagttta
    31561 aagtgttttc acttatttca acacttgtca ttgtcatttt agcaattata agatttgttc
    31621 ataaaatgat gtaattagag tgagacattg ttttatgtct caggatccag ttatttatta
    31681 tagctacaat atttacgatg atataaataa cccgagattt tagtatgatt catttcacta
    31741 aagtctcggg tttctatttg ataattttta atagggcatg gcttgtatat gcgcctgcct
    31801 tttatctcat ttccaatgat taatctggat attgttctaa aaatgctttc gcttctttat
    31861 taactgtttt aaaatcaata ccttgttgca tcgctgcaaa gacacatcca caataacact
    31921 gcctaaagat attatagtca ttacacattt ctatggaacg ctcataacct ttacttttct
    31981 taaaatcact tggcaaatag ttcacatcgt atattttttg gacatccata ccaagttcat
    32041 tgattaattg tgcgttcttt ttaggtgata atgtaattgc actgccaaaa taatcatagc
    32101 catgttctac agctgctttc gctacaatat ccaaacgcat ttcaaaacaa gcggtacaac
    32161 gtaagccgcc ttctttttca tcagctaatt ctttatcctt caccattttc acaaacttat
    32221 gcggttcata aggtgcttca atatacttca cattcgcacc agtcttgcga ttaaaatctt
    32281 ctacaaattg ttcttgcact ttagcacgtc gtaaatattc atttttcgga tgaatatttg
    32341 aattcgcgaa ataaattgca atgtctgcat attgtgttaa aaactctaat gtatatgtac
    32401 tacaaggtgc acaacaacta tgcaataaga ttttaggtct gattgcttct ctttcccact
    32461 gcccgattaa tttcttcaac accttgtcat aattaatttt ttgatttttc attttactga
    32521 taataggttc agcattaatc atgatttaac ctcccacatt taatcattaa cttctattat
    32581 atatgattca tattaaatgt cagtcaaaaa agttagaaat tcattttaat gcatttatat
    32641 ttcgaaagtc ccttatgtat ctaaaagcat tttttaaact tgaattttaa aacactaaac
    32701 aacacatacg tctctgtgtc attttcattt tttgtatgtc atatatatgt ttacttcatt
    32761 taaatcaatt tcatcttata atttatcgtg tattttacaa aagattgact tcaattcatc
    32821 ataaaagtta tacttttgcc attttttaat gtaacatggt gttagtaata aaaataatac
    32881 attgaggtgt tttacatgac agcattattc ccttatatcg cttttaaaaa ttcaaaagaa
    32941 gcccttgcat attacgaaga agtatttggt gcaactgacg ttaaacgttt agaagttggc
    33001 gaagaacaag cgtcacattt tggtatgact aaggaagaag cgcaagaagc aactatgcat
    33061 gctgagtttg aagtgcttgg cgtaaaagtg ttatgttctg attcttttgg tcgcgctgac
    33121 aaaattaata atggcatatc attattaatt gattatgatg ttaacaataa ggaagatgct
    33181 gataaagttg aagcattcta tgagcaaatt aaagatcatt cttcaattga aatagaatta
    33241 ccgttagctg accaattctg gggtggcaaa atgggcatct ttaccgataa atacggtgtt
    33301 cgttggatgt tacatggtca agactatact gcaatccaac aataatgtta ttgataaaga
    33361 tatcatttaa taagcttagg ttatttagca aggcaagcca ctctcgattc atggcttgcc
    33421 ttattttatt gtatattttt aattatcgtt gctggccctt gattgacaat cgtattaaaa
    33481 tgccttatta agtcaacttt gtctatacgg tttggatctt ctacccaatg tcttatcaaa
    33541 gacaatcccg cacctgaaac ataactcatg aaataggaaa atggtatacc attaatttga
    33601 tcattttcat ttttataacg ttgtaaatga cacataatta aatcataaag tttttcgtgg
    33661 atatttgaat ctttacccat acgaaacatc aattgataaa atgcgatgtc tttttctatc
    33721 atttctatta aaacggtcat aatttgatgt atattatccg tggataactt aactgctcca
    33781 tttaacttct catcatgaat gaagtctctt atttcctcca actgctgatt ctctaatttt
    33841 tctagcaaat catatttatc ataataatgc gtataaaatg tactacggtt aacatcagct
    33901 aaatctgcaa tttgttgcac agtaatctct tctaattggt gttgatgtaa aagttcaata
    33961 aatgcatttc tcattgcaac ttgtgatttt ctaatacgtc gatctatagt catttgtatc
    34021 aagtcctccc caatgattat taacaattat aaacgttatg ttcattatcc cacaaatctc
    34081 caacattgat gattggcaca caatgtttac ctgtttaata taggtgatac aaacaaacag
    34141 aaaaaggtga taacaatgaa ccaacattta ctaggaaatc caaaattaac tgtaactcat
    34201 gtcaatgaag tgaaagccgg tattaaccac atcgttgtcg acagtgttca atatggaaat
    34261 caagaaatga ttatggaaaa agatgtcact gtggaaatgc gcgatggcga aaaattatat
    34321 attaatattt tcagaccaaa taaagatggc aaattccctg tagttatgtc tgcagatact
    34381 tacggtaaag ataataagcc taaaatcaca aatatgggtg ccctttggcc aacattaggc
    34441 gccattccga catctagttt tacacctgaa gaatcaccag acccaggatt ttgggtgcca
    34501 aatgattatg ttgtagttaa agttgcatta cgcggtagtg acaaatcaaa aggcgtctta
    34561 tctccatggt caaaaagaga agcggaagat tattacgaag tgattgaatg ggcagcaaaa
    34621 cagccatgga gtaatggaaa tatcggaaca aatggtgttt cttatcttgc ggtgactcaa
    34681 tggtgggtcg catcattaaa tccaccacat ttaaaagcaa tgattccttg ggaaggatta
    34741 aatgatatgt atagagaagt agcctttcac ggaggtatac cggatactgg cttttatcgt
    34801 ttctggatac aaggtatttt tgcgagatgg acagataatc caaatatcga agacatgatt
    34861 caagcacaac aagaacaccc tttgttcgat gatttttgga aacagcgtca agtgccatta
    34921 tcacaaatta aaacacctct actaacatgt gctagttggt ctacacaagg tttgcacaac
    34981 cgtggctctt ttgaaggatt taaacaagct gcatctgaag aaaaatggct atatgtgcat
    35041 ggacgtaaag agtgggaaag ttactacgct agagaaaatc tcgaacgcca aaaatcattc
    35101 tttgattttt accttaaaga agaaaataac gattggaaag atacgcctca tgtcatttat
    35161 gaagttagag atcaatttta taaaggcgaa ttcaaatcag cgtcagcgtt ccctttacct
    35221 aacacagaat atacaccatt gtatttgaat gctgaaaatc acacattgaa tcatgcaaag
    35281 attagtagcg cgcatgtcgc acaatatgac tctgaagata aacgacaaga tgtaagtttt
    35341 aaatatacgt ttgacaaaga tactgagtta gttggaaaca tgaacttaaa actatgggta
    35401 agcactaaag actcagacga tatggattta tttgcaggta ttaaaaagtt agatcgtcgt
    35461 ggtaatgaag ttaacttccc tgattttaat catattgaaa atggtcaagt agctaccggt
    35521 tggttacgcg tatcacatcg tgaattagat caagaaaaat ccacaattgc gcaaccttgg
    35581 cataaacatg aaacagaatt aaagttgtca caagatgaga ttgtacctgt tgaaatcgaa
    35641 ttgttacctt caggcacgct atttaaacaa ggcgaaacat tggaagttgt tgtaaaaggt
    35701 agtgaaattg taattggtaa tagtacccct ggcatgaaaa cgcgttatga acatgaagaa
    35761 accgtaaata aaggcatgca catgatttat actggtggta aatatgattc acaattaatc
    35821 attcctatcg ttaattgata tgcagcaatt acggtcgctt ttgattaaaa gtgacatagt
    35881 gatagaactg tataacaaga gcaggccaca cgcttggaat cttaaaccaa ggtgtggccc
    35941 tttttattat tgatggctat ttaattttat aaatcttgtc actaaactta ctacaagcaa
    36001 tattaaacca ataaataaaa ccataattgc tgtattactt tcgttattta ctcctgtttt
    36061 tggtaattct ttcaattgtt gcttatgtac tgacttgctc ttgctatcca aatgaatact
    36121 ttgttgttta gccatttgtt tattactttt tgtgtgaata tcatttgctt taatacttgg
    36181 atttacagca ctattattcg atgttccatt tgcgtttttc aactgattaa taacatttgg
    36241 atctttcgtg ccatccatta aattatctgg atgttttagt aaatgtctgc agtcggatac
    36301 tattttagaa tcttttgcct ttaccgcatt attcggcacc tcattatcat ctttcaactg
    36361 cttgataaca tctggatctt tcgtgccatc tattaaatta tcaagttttt tcacacgtgc
    36421 tatgtcacta actggccctg gataatttgc atccggttgt ctaactggta ttaaattgct
    36481 gttttcattc acaccttcag gcttgttatt ttcggcgttc gcattatccg taaaaatcaa
    36541 cactgataaa attgcaacaa ataaacttat aacttttttc atcttattca tcctttccta
    36601 ttttactacc ttaatatcat tgctattaaa gtaacccatc catctatttt tttcgtcgta
    36661 taaagagtaa tatttatacc catttggaat attgtaatag agtttagctg tgtacgcttt
    36721 atctttttta attaatttat tatcaccctt ttttgtaatt tcaatgtttt tccaatatat
    36781 atacttactt ttaattactt tcactttctt attatatgga tgacttctgt acttacctat
    36841 ccaataattt atgtaatcta attttaaatc atttattctc acgcctgaat tatgattata
    36901 tctgccgtat gcatgtactc cgatgatatt gttttttgaa tctcttatcg cactaccact
    36961 ttgtcctgaa aatgtgtcta ccgtataata catttcattc tcatcaaaac tttctaattt
    37021 ccctttacct ttatattgtc tgttgtctga cttgtctcct ggaaatccag aaatttcaat
    37081 attttcacct ttgctaatgc gtgtgttcaa agttaagtaa cctgttttat ttcctaaatt
    37141 actatttaac ttaataattg ctatatcttc ttttgtagga gcattattaa tccaagattt
    37201 agatacaaaa aacttatgcg aaaaggcctt tcctattgta tatgtttgcc catttactcc
    37261 agcatagaca tcaatctttt tagcccaacc cttatcgtct ttagaataga cattatgagc
    37321 cgctgtcaat acaatgtcct taccaatcat agtaccggtg cctttatata cacggttatt
    37381 tgaaaacgtc atatttaata atacagtctg cttataaggt ctttgtaaaa tattattaac
    37441 aaccgttctt tgatctttac cgaaaactcg ctcagttaag ggcgtactat aatcacctac
    37501 ttcataaagc tcattttgat tacgttcaat tgttcctgat tcaaaattat tatcactacc
    37561 attttctgaa ttgacgatag gattattatc agctaagaca aaactttcac cataataact
    37621 agaaacaatt actactaaca aaatcaaaaa tgatatttta aaaatttttg tcataggcat
    37681 tcctccttta atctata
//
LOCUS       DAPSKH010000022        36980 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPSKH010000022 DAPSKH010000000
VERSION     DAPSKH010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36980
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.022"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            349..750
                     /locus_tag="RPH49_001198"
     CDS             349..750
                     /locus_tag="RPH49_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5124364.1"
                     /translation="MKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILL
                     TLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQ
                     QEKVELLNFISDAIASRATAMQNSLNAIIAV"
     gene            complement(870..1433)
                     /locus_tag="RPH49_001199"
     CDS             complement(870..1433)
                     /locus_tag="RPH49_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5124365.1"
                     /translation="MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPE
                     GHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDTHKGHIDAAIFNLGYL
                     PKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQ
                     KHAQVLQYQFLNQRNHAPFICAIEKIS"
     gene            complement(1430..2383)
                     /locus_tag="RPH49_001200"
     CDS             complement(1430..2383)
                     /locus_tag="RPH49_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500380.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDY5124366.1"
                     /translation="MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRD
                     GTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTH
                     APVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIH
                     QSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDV
                     QGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGP
                     IDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ"
     gene            2494..3675
                     /locus_tag="RPH49_001201"
     CDS             2494..3675
                     /locus_tag="RPH49_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124367.1"
                     /translation="MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAG
                     LVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLV
                     MLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYI
                     FLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICW
                     VAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPVLYLLKGNLKKQMF
                     VGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQG
                     FVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKID
                     A"
     gene            3963..6380
                     /locus_tag="RPH49_001202"
     CDS             3963..6380
                     /locus_tag="RPH49_001202"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDY5124368.1"
                     /translation="MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPS
                     GAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTK
                     KNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCP
                     ALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDM
                     QRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYK
                     EKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTG
                     AIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAI
                     TKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLL
                     PETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPK
                     NENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPFQKLFN
                     QGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGS
                     RRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLM
                     VFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTFDEALL
                     VDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQK
                     LVNIVAK"
     gene            6402..6713
                     /locus_tag="RPH49_001203"
     CDS             6402..6713
                     /locus_tag="RPH49_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDY5124369.1"
                     /translation="MKSITTDELKNKLLESKPVQIVDVRTDEETAMGYIPNAKLIPMD
                     TIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKS
                     I"
     gene            7039..13608
                     /gene="sasC"
                     /locus_tag="RPH49_001204"
     CDS             7039..13608
                     /gene="sasC"
                     /locus_tag="RPH49_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored repetitive surface protein SasC"
                     /protein_id="HDY5124370.1"
                     /translation="MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDQNV
                     QGESNQALPGNSHNTNVDTSRDITNSSQNTPNQHTTANASTNQALANHHNVGESNQVV
                     PMPVQPSTSSASNNNHSDAKSTATESAANTNNNLSSNNNTLNVPNNTDNNDSARHLTL
                     KEIQEDVRHSSDKPELVAIAEEASNRPKKRSRRAAPADPNATPADPTATPADPAAGNG
                     SAPVAITAPYTPTTDPNANNIGQNAPNEVLSFDDNGIRPSTNRSVPTVTVVDNLPGFT
                     LINGGKVGVFSHAMVRTSMFDSGDAKNYQAQGNVIALGRIRGNDVNDHGDFNGIEKTL
                     TVNPNSELIFEFNTMTTKNYQGMTNLVIKNADNDAVIGEKVVAYGPIWRLFKVPENVS
                     HLKIQFVPKNDAITDPRGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNK
                     EFSVTTSLKNNGNFGASFNTDDFVYKIQLPEGVEYVNNSLTKDFQSGNSGVDINDFNV
                     TYDAANRIITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKT
                     FSQDFINSPAESHTVSTEPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKRR
                     AQTILDENRNNVPLNKRVSQADIDSLANQMQHTLIRSVDAENAVNRKVDDMEDLVNQN
                     DELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSRDTATPVVKPN
                     AKQAIRDKAAKQREIINNTPDATQDEIQDALNQLTTDETDAIDNVTNATTNADVETAK
                     NNGINTIGAVVPQVTHKQAARDAINQATATKRQQINSNREATQEEKNAALNELTQATN
                     HALEQINQATTNDDVDTAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANP
                     DATQEERQAAIDKVNAAVAAANANILNANTNADVEQVKTNAIQGIQAIEPATKVKTDA
                     KNAIDQSAETQHNAIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKD
                     QGMQNIVVIQPATQVKTDARNTVNEKAREVITNINATPGATREEKQEAIDRVNALKNR
                     ALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTN
                     ATTEEKQIALNQVDQELAAALNNINQADTNAEVDQAQQLGAQAINAIQPNIVKKPAAL
                     AQINQHYNAKLAEINATPDATDDEKNAAINTLNQDRQQAIESLNQANTNNEVDQAAIT
                     AENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQA
                     FNQINQNQTNDQVDATTNQAINAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSIDS
                     TDNEKEVATQALAREKEKALVAIEQAQTNEQVNQAATDGITAIKIIQPETRVKPAARE
                     KINQKANELRAQINQDKEATAEERQAALDKINDLVTQAMTNITSDRTDQQVNDSTNQA
                     LGDIALVTPDHIIRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKRAL
                     QNIDQAIANNDVKRVESNGIATLKGVEPHIVVKPEAQQAIKASADNQVESIKDTPHAT
                     TDELDEANQQINDTLKQGQQDIDNTTQDVAVNDVRNQTIKAIEQIKPKVRRKRAALDN
                     IDESNNNQLDAIRNTLDTTQDERNIAIAELNKIVNTIKNDIAQNKTNAEVDQTEADGN
                     NNIKVILPKVQVKPAARHSVSAKAEAQNALIDQSDLSTEEERLAAKHLVDQALNQAID
                     QINHADKTAQVNQNSIDAQKIISQIKPATTVKTTALQQIQNIATNKINLIKANNEATD
                     EEQNAAIAQVEQALIKAKQQIASAVTNADVAYLLHDGKNEIREIEPVINRKSTAREQL
                     TTLLNDKKQAIEANVQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQ
                     TIHDLDVHPIKKPDAEKTINDDLARVTHLVQNYRKVSDRNKADALKAITALKLQMDEE
                     LKIARTNADVDAVLKRFKVALGDIEAVITEKENSLLRIDNIAQQTYAKFKSIATPEQL
                     AKVKALIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEVTNVSPKVGQPA
                     PKVCTPIKKEDKQEVHKVEKELPNTGSEEMDLPLKELALITGAALLARRRTKNEKES"
     gene            complement(13725..14993)
                     /locus_tag="RPH49_001205"
     CDS             complement(13725..14993)
                     /locus_tag="RPH49_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDY5124371.1"
                     /translation="MYQTIIIGGGPSGLMAAVAASEQSSNVLLIEKKKGLGRKLKISG
                     GGRCNVTNRLPYAEIIKNIPGNGKFLYSPFSIFDNESIIDFFESRGVKLKEEDHGRMF
                     PVSNKAQDVVDTLVTTIERQHVTIKEEEAVSRIEVKEDQTFTVHTQNNSYESHSLVIA
                     TGGTSVPQTGSTGDGYKFAQDLGHTITELFPTEVPITSAEPFIKSNRLKGLSLKDVEL
                     SVLKKNAKKRISHQMDMLFTHFGISGPAALRCSQFVYKEQKNQKTQHISMAIDAFPEL
                     NHEQLKQHITSLLSDTPDKIIKNSLHGLIEERYLLFMLEQAGIDENTTSHHLSNQQLN
                     DLVNMFKGFVFKVNGTLPIDKAFVTGGGVSLKEIQPKTMMSKLVPGLFLCGEVLDIHG
                     YTGGYNITSALVTGHVAGLYAGHYAHASME"
     gene            15399..17060
                     /locus_tag="RPH49_001206"
     CDS             15399..17060
                     /locus_tag="RPH49_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDY5124372.1"
                     /translation="MSESKEMVRGTFLITISILITKVLGVLFIIPFNYLIGGQENMAP
                     FTYAYAPYNIAIAVATAGVPLAASKYVAKYNAIGAYKVSQKFYKSSFIVMSITGVLGF
                     LVLYFLAPYISELTLARNVHDKNGWSVDDITWIIRIISMVVIFIPVLATWRGIFQGYK
                     SMGPTAVSEVTEQIARVIFILIGSYLVLNVFDGSILLANGIATFAAAVGAIIGIFTLW
                     YYWRKRKHNIDRMVESDYTDIDVSYGKMYKEIIAYSIPFVIVSLNYPLFNLVDQFTHN
                     GALSLVGIPSQLQDIFFNMLNMSTNKIVMIPTSLSAGFAVSLIPYITKTFAEGRLHEM
                     HHQIRTSIGVLMFITVPASIGIMALAQPLFTVFYGYDPIVLGHDPNHDGSRLLFYYAP
                     VAILISLLSVTASMLQGIDKQKLTVYVILASVVIKLALNYPLIMLFHTPGAILSTSIA
                     LLFAIGCNFYILKKYAKFKFSYSWIHFAKIFLYSFIMMLGVELVFFLANLFLEPTKLG
                     YLIIIILGVTVGILIYGTITIKTRLADEFLGEIPEKLRRRVRFLR"
     gene            17057..17752
                     /locus_tag="RPH49_001207"
     CDS             17057..17752
                     /locus_tag="RPH49_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDY5124373.1"
                     /translation="MRIDKFLANMGVGTRNEVKQLLKKGFVNVNEQVIKSAKTHIEPE
                     NDKISVRGELIEYVENVYIMLNKPKGYISATEDHHSKTVIDLIPEYQHLNIFPVGRLD
                     KDTEGLLLITNDGDFNHELMSPNKHVSKKYEVISANPITEDDIQAFKEGITLSDGKVK
                     PAILTYIDNQTSHVTIYEGKYHQVKRMFHSIQNEVLHLRRIKIADLELDSNLDSGEYR
                     LLTENDFDKLNYK"
     gene            17769..18191
                     /locus_tag="RPH49_001208"
     CDS             17769..18191
                     /locus_tag="RPH49_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDY5124374.1"
                     /translation="MAKGNLFKAILGIGGAVAAVLVTRKDSRDKLKAEYNKYKQDPQS
                     YKDNAKDKATQLGTIANETIKEVKTNPKEYANRLKNNPKAFFEEEKSKFTEYDNKTDE
                     SIEKGKFDDEGGVAPNNNLRIVTEEDLKKNKNALSDKE"
     gene            18394..19803
                     /gene="sapep"
                     /locus_tag="RPH49_001209"
     CDS             18394..19803
                     /gene="sapep"
                     /locus_tag="RPH49_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mn(2+)-dependent dipeptidase Sapep"
                     /protein_id="HDY5124375.1"
                     /translation="MWKEKVQQYEDQIINDLKGLLAIESVRDDAKASEDAPVGPGPRK
                     ALDYMYEIAHRDGFTTHDVDHIAGRIEAGKGNDVLGILCHVDVVPAGDGWDSNPFEPV
                     VTEDAIIARGTLDDKGPTIAAYYAIKILEDMNVDWKKRIHMIIGTDEESDWKCTDRYF
                     KTEEMPTLGFAPDAEFPCIHGEKGITTFDLVQNKLTEDQDEPDYELITFKSGERYNMV
                     PDHAEARVLVKENMTDVIQDFEYFLEQNHLQGDSTVDSGILVLTVEGKAVHGMDPSIG
                     VNAGLYLLKFLASLNLDNNAQAFVAFSNRYLFNSDFGEKMGMKFHTDVMGDVTTNIGV
                     ITYDNENAGLFGINLRYPEGFEFEKAMDRFANEIQQYGFEVKLGKVQPPHYVDKNDPF
                     VQKLVTAYRNQTNDMTEPYTIGGGTYARNLDKGVAFGAMFSDSEDLMHQKNEYITKKQ
                     LFNATSIYLEAIYSLCVEE"
     gene            19807..20655
                     /gene="dat"
                     /locus_tag="RPH49_001210"
     CDS             19807..20655
                     /gene="dat"
                     /locus_tag="RPH49_001210"
                     /EC_number="2.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino-acid transaminase"
                     /protein_id="HDY5124376.1"
                     /translation="MEKIFLNGEFVSPSEAKVSYNDRGYVFGDGIYEYIRVYNGKLFT
                     VTEHYERFLRSANEIGLDLNYSVEELIELSRKLVDMNQIETGAIYIQATRGVAERNHS
                     FPTPEVEPAIVAYTKSYDRPYDHLENGVNGVTVEDIRWLRCDIKSLNLLGNVLAKEYA
                     VKYNAVEAIQHRGETVTEGSSSNAYAIKDGVIYTHPINNYILNGITRIVIKKIAEDYN
                     IPFKEETFTVDFLRNADEVIVSSTSAEVTPVIKLDGEPVNDGKVGPITRQLQEGFEKY
                     IESHSI"
     gene            21206..21997
                     /locus_tag="RPH49_001211"
     CDS             21206..21997
                     /locus_tag="RPH49_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001602611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDY5124377.1"
                     /translation="MEQFYQLGWTLDSAGGASGEAYMAEQDGQKLFLKRNSNPFIAAL
                     SAEGIVPKLVWTKRIETGEVVTAQHWKNGRELSSNEMKQTRVAHLLKKIHNSRPLLSM
                     LKRMEMEPITPEIMLNKINASLSREVLTHHIVRKSLTYLEEHIPSLDSRFFTVVHGDV
                     NHNNWLLSDRDELFLVDWEGAMIADPAIDIGMLLYNYVPQQQWSEWLETYGVQESLNL
                     NKRMKWYTVIQSIGLVQWYEEQKRYKDMNTWLKFLNEVMNSNMFI"
     gene            22012..22656
                     /gene="trmB"
                     /locus_tag="RPH49_001212"
     CDS             22012..22656
                     /gene="trmB"
                     /locus_tag="RPH49_001212"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDY5124378.1"
                     /translation="MRVRYKPWAEDYLKDHPELVDMDGQHAGKMTEWFDKTQPIHIEI
                     GSGMGQFITTLAAQNPHINYISMEREKSIVYKVLDKVKEMSLTNLKIICNDAIELNEY
                     FKDGEVSRIYLNFSDPWPKNRHAKRRLTYHTFLALYQQILNDEGDLHFKTDNRGLFAY
                     SLESMSQFGMYFTKINLNLHQEDDGSNILTEYEKKFSNKGSRIYRMEAKFHSQK"
     gene            23126..23968
                     /locus_tag="RPH49_001213"
     CDS             23126..23968
                     /locus_tag="RPH49_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDY5124379.1"
                     /translation="MKIGDISIHYLNGGNTKMDGGAMFGVVPKPLWSKQYNANERNQI
                     NLPTHPILIQTAQYNLIIDAGIGNGKLSEKQLRNFGVDEESHIIADLANYNLTPKDID
                     YVLMTHMHFDHAAGLTDQAGHAIFENAIHVVQQDEWHEFIAPNIRSKSTYWDKNKGDY
                     SNKLILFEKHFEPVPGIKMQHSGGHSFGHTIITIESQGDKAVHMGDIFPTTAHKNPLW
                     VTAYDDYPMQSIREKERMIPYFIQQQYWFLFYHDENYFAVKYSDDGENIDAYILRETL
                     VDNN"
     gene            complement(24093..24404)
                     /locus_tag="RPH49_001214"
     CDS             complement(24093..24404)
                     /locus_tag="RPH49_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDY5124380.1"
                     /translation="MTKLKYIIPTIIAVAIVIISTISIIQFINRKRYNPVKVLNEVKS
                     YFMNVKGSYIVYEPFVHPETDKYRLVYQGGITTIKNGQNIHYDFYADAYTGEVINIVE
                     R"
     gene            24491..25567
                     /locus_tag="RPH49_001215"
     CDS             24491..25567
                     /locus_tag="RPH49_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDY5124381.1"
                     /translation="MNINKKVTLQRIQTLTELHGAPGFEEEVKNYMTQQMAPYVDEFI
                     ENRMGGFFGVKKSKNPNAKRVMIAAHMDEIGFMITNITKNGMIQFTNLGGVANDIWQG
                     QRLVIKNRNGDKIIGVVSNIPKHFRTGSEGAPEIKDLTLDIGAQNEDEVRERGIDIGD
                     TIVPHTPFTQLSEHRYSAKAWDNRYGCVLAIEILELLKDIELDVDLYVGANVQEEVGL
                     RGAKASAEMIDPDVAFVVDCSPANDVKGNQPLSGELGKGTLIRIKDGTMILKPVFRDY
                     LLKLVEAHDIEHQYYMSPGGTDGGEIHKANIGIPTAVIGVCARYIHSTDSVFDIRDYF
                     AARSLLSEAICNLDNNQIETLQYK"
     gene            25632..25943
                     /locus_tag="RPH49_001216"
     CDS             25632..25943
                     /locus_tag="RPH49_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDY5124382.1"
                     /translation="MKQLESEQQFESLKQGATVFEFTAGWCPDCRVIEPDLPELEARY
                     PMFDFVSVDRDKFMDICIENGIMGIPSFLVYKNGELLGSYIGKERKSIEKIDAFLAQY
                     V"
     gene            26043..26900
                     /locus_tag="RPH49_001217"
     CDS             26043..26900
                     /locus_tag="RPH49_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1444 domain-containing protein"
                     /protein_id="HDY5124383.1"
                     /translation="MNTFQMRDKLKERLSHLDVDFKFNREEETLRIYRTDNNKGITIK
                     LNAIVAKYEDKKEKIVDEIVYYVDEAIAQMADKTLESISSSQIMPVIRATSFDKKTKQ
                     GVPFIYDEHSAETAVYYAVDLGKSYRLIDESMLEDLKLTEQQIREMSLFNVRKLSNSY
                     TTDEVKGNIFYFINSNDGYDASRILNTAFLNEIEAQCQGEMLVAVPHQDVLIIADIRN
                     KTGYDVMAHLTMEFFTKGLVPITSLSFGYKQGHLEPIFILGKNNKQKRDPNVIQRLEA
                     NRRKFNKDK"
     gene            26929..27525
                     /locus_tag="RPH49_001218"
     CDS             26929..27525
                     /locus_tag="RPH49_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDY5124384.1"
                     /translation="MNLFYNPKYVGDVAFLQIEPVEGELNYNKKGNVVEITNEGNVVG
                     YNIFEISKDITIEEKGHIKLTDELVNVFQKRISEAGFDYKLNADLSPKFVVGYVETKD
                     KHPDADKLSVLNVNVGNDTLQIVCGAPNVEAGQKVVVAKVGAVMPSGMVIKDAELRGV
                     ASSGMICSMKELNLPNAPEEKGIMVLNDSYEIGQAFFE"
     gene            27546..31370
                     /locus_tag="RPH49_001219"
     CDS             27546..31370
                     /locus_tag="RPH49_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDY5124385.1"
                     /translation="MSWFDKLFGEDNDSNDDLIHRKKKRRQESQNIDNDHDSLLPQNN
                     DIYSRPRGKFRFPMSVAYENENVEQSADTISDEKEQYHRDYRKQSHDSRSQKRHRRRR
                     NQTTEEQNYSEQRGNSKISQQSIKYKDHSHYHTNKPGTYVSAINGIEKETHKSKTHNM
                     YSNNTNHRAKDSTPDYHKESFKTSEVPSAIFGTMKPKKLENGRIPVSKPSEKVESDKQ
                     KYDKYVAKTQTSQNKQLEQEKQNDSVVKQGTASKSSDENVSSTTKSMPNYSKVDNTIK
                     IENIYASQIVEEIRRERERKVLQKRRFKKALQQKREEHKNEEQDAIQRAIDEMYAKQA
                     ERYVGDSSLNDDSDLIDNSTDASQLHTNGIENETVSNDENKQASIQNEDTNDTHVDES
                     PYNYEEVSLNQVSTTKQLSDDEVTVSNVTSQHQSALQHNVEVNDKDELKNQSRLIADS
                     EEDGATNKEEYSGSQIDDAEFYELNDTEADEDTTSNIEDNTNRNASEMHVDAPKTQEH
                     AVTESQVNNIDKTVDNEIELAPRHKKDDQTNLSVNSLKTNDVNDGHVVEDSSMNEIEK
                     HNAEITENVQNEAAESEQNVEEKTIENVNPKKQTEKVSTLSKRPFNVVMTPSDKKRMM
                     DRKKHSKVNVSELKPVQSKQAVSESKPASQAAPSSSSDSQESNTNAYKTNNMTSNNVE
                     NNQLIGHAETENDYQNAQQYSEQKPSADSTQTEIFEESQDDNQLENEQVDQSTSSSVS
                     EVSDITEESEETTHPNNTSGQQDNDDQQKDLQPSFSNQNEDTANENRPRTNQQDVATN
                     QAVQTSKPMIRKGPNIKLPSVSLLEEPQVIEPDEDWITDKKKELNDALFYFNVPAEVQ
                     DVTEGPSVTRFELSVEKGVKVSRITALQDDIKMALAAKDIRIEAPIPGTSRVGIEVPN
                     QNPTTVNLRSIIESPSFKNAESKLTVAMGYRINNEPLLMDIAKTPHALIAGATGSGKS
                     VCINSILMSLLYKNHPEELRLLLIDPKMVELAPYNGLPHLVAPVITDVKAATQSLKWA
                     VEEMERRYKLFAHYHVRNITAFNKKAPYDERMPKIVIVIDELADLMMMAPQEVEQSIA
                     RIAQKARACGIHMLVATQRPSVNVITGLIKANIPTRIAFMVSSSVDSRTILDSGGAER
                     LLGYGDMLYLGSGMNKPIRVQGTFVSDDEIDDVVDFIKQQREPDYLFEEKELLKKTQT
                     QSQDELFDDVCAFMVNEGHISTSLIQRHFQIGYNRAARIIDQLEQLGYVSSANGSKPR
                     DVYVTEADLNKE"
     gene            31394..32707
                     /locus_tag="RPH49_001220"
     CDS             31394..32707
                     /locus_tag="RPH49_001220"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDY5124386.1"
                     /translation="MTHYHFVGIKGSGMSSLAQIMNDLGHEVQGSDIENYVFTEVALR
                     NKGIKILPFDANNIKEDMVVIQGNAFASSHEEIVRAHQLKIDVVSYNDFLGQIIDQYT
                     SVAVTGAHGKTSTTGLLSHVMNGDKKTSFLIGDGTGMGLPESDYFAFEACEYRRHFLS
                     YKPDYAIMTNIDFDHPDYFKDINDVFDAFQEMAHNVKKGIIAWGDDEHLRKIEADVPI
                     YYYGFKDSDDIYAQNIQITDKGTAFDVYVDGEFYDHFLSPQYGDHTVLNALAVIAISY
                     LEKLDVTNIKEALETFGGVKRRFNETTIANQVIVDDYAHHPREISATIETARKKYPHK
                     EVVAVFQPHTFSRTQAFLNEFAESLSKADRVFLCEIFGSIRENTGALTIQDLIDKIEG
                     ASLINEDSINVLEQFDNAVILFMGAGDIQKLQNAYLDKLGMKNAF"
     gene            32781..33272
                     /locus_tag="RPH49_001221"
     CDS             32781..33272
                     /locus_tag="RPH49_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDY5124387.1"
                     /translation="MDWILPIAGIIAAIAFLILCIGIVAVLNSVKKNLDYVAKTLDGV
                     EGQVQGITRETTDLLHKVNRLTEDIQGKVDRLNSVVDAVKGIGDSVQTLNSSVDRVTN
                     SITHNISQNEDKISQVVQWSNVAMEIADKWQNRHYRRGSANYKANNVATDANHSYTSR
                     VDK"
     gene            33346..34704
                     /locus_tag="RPH49_001222"
     CDS             33346..34704
                     /locus_tag="RPH49_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124388.1"
                     /translation="MTQQQNNKRTLKNKHTYHNELLPNRKDFVVSFITGALVGSALGL
                     YFKNKVYQKADDLKVKEQELSQKFEERKTQLEETVAFTKERVEGFLNKSKNEQAALKA
                     QQAAIKEEASANNLSDTSQEAQEIQEAKKEAQAETDKSAEVSNKESKAVALKAQQAAI
                     KEEASVNNLSDTSQEAQEIQEAKKEAQAETDKSAAVSNEESKAVALKAQQAAIKEEAS
                     ANNLSDTSQEAQEIQEAKKEAQAETDKSEAVSNEESKAVALKVSKEESQAERLANAAK
                     QKQAKLTPGSKESQLTEALFAEKPVAKNDLKEIPQLITKKNDVSETVNTDNKDTVKQK
                     EAKFENGVITRKADEKTTNNTDVDKKSGKQSKKTTPSNKRNASKASTNKTSGQKKQHN
                     KKSSQGAKKQSSSSKSTQKNNQTSNKNSKATNAKSSNASKKSNAKVEKAKSKIEKRTF
                     ND"
     gene            34860..34943
                     /locus_tag="RPH49_001223"
     CDS             34860..34943
                     /locus_tag="RPH49_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124389.1"
                     /translation="MLFVTSLDYNSDIAHFKLKMEKYSIIK"
     gene            35398..36489
                     /locus_tag="RPH49_001224"
     CDS             35398..36489
                     /locus_tag="RPH49_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-deoxy-7-phosphoheptulonate
                     synthase/chorismate mutase"
                     /protein_id="HDY5124390.1"
                     /translation="MSNKLESYRSEIVSLNHQILDLLSKRGELAQKIGEEKLKQGTRI
                     YDPQREKEMLNDLIDSNKGPFNDNTIKQLFKEIFKASTDLQKSENEKHLYVSRKLKPE
                     DTIVTFDNGGIIGDGNKSFVFGPCSVESFEQVEAVAKNLHAKGEKFIRGGAFKPRTSP
                     YDFQGLGVEGLKILKQIKDKYDLNVVSEIVNPNDFEVADEYLDVFQIGARNMQNFELL
                     KEAGRTKKPILLKRGLSATIEEFVYAAEYIASQGNQNIILCERGIRTYEKATRNTLDI
                     SAVPILKQGTHLPVMVDVTHSTGRKDIMLPTAKAALAVGADGVMAEVHPDPSVALSDA
                     GQQMDLDEFQAFYDELKPLSDLYNAKKLK"
     gene            36842..36955
                     /locus_tag="RPH49_001225"
     CDS             36842..36955
                     /locus_tag="RPH49_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124391.1"
                     /translation="MKKVYIKLKYIVRYHLAFVFISSFSLNFSKQKYVTVN"
BASE COUNT        13780 a         5297 c         6811 g        11092 t
ORIGIN      
        1 tgtaataaaa attcaatgcg tatctttttt gaagaaatat atgtagaatt gttgcaattt
       61 aatggtaata ttgatatatt ttctttgtat ataaattata aaattaatat gtaatagagt
      121 gatttgtttt atgtactatt atcttatttc taaatattaa ctctattgat tattggtttt
      181 tatacttatt taattttatt caactttgac aattgaatag aaagcaagtt tatttacact
      241 tgtagtttta tgcataagtt agcacataca agttttggga ttgttgggat gtttgttaat
      301 acttgtatgg tagctaaata tgtgattatt aattgggaga tgtttagcat gaaaaaagta
      361 aataacgaca ctgtatttgg gattttgcaa ttagaaacac ttttgggtga cattaactca
      421 attttcagcg agattgaaag cgaatacaaa atgtctagag aagaaatttt aattttacta
      481 actttatggc aaaaaggttc tatgacgctt aaagaaatgg acagatttgt tgaagttaaa
      541 ccgtataagc gtacgagaac gtataataat ttagttgaat tagaatggat ttacaaagag
      601 cgtcctgttg acgatgaaag aacagttatt attcatttca atgaaaagtt acaacaagag
      661 aaagtagagt tgttgaattt catcagtgat gcgattgcaa gtagagcaac agcaatgcaa
      721 aatagtttaa acgcaattat tgctgtgtaa gtttaatagc ataaaaagag gttttcatta
      781 agttgaaaac ctctttttgt tgttggtatt aatttttcaa atgttgacta ctcaatccta
      841 aattataaat agtatagcgc agcaaatgct taagaaattt tttctatggc acaaatgaat
      901 ggagcatgat tacgttggtt taaaaattga tattgcaaaa cttgcgcatg cttttgatcc
      961 aaagtactca agtaatcaag caatgcatgc ttctcaattt gtccttcgct atgaccatga
     1021 tatataacaa gtacaataat accttcaatt gacattaatg atagcaatga attaatagct
     1081 tggattgtcg tgtcaggctt tgtcacgata gatttatcac ctttaggcaa ataacctagg
     1141 ttaaagatgg ctgcatcaat atgaccttta tgtgtatcat ttatatgatg ttcaatattt
     1201 tcatgtccat cttttattaa agaaacatga ttgaaatcct taactttatc acgtgtattt
     1261 tccaaagcta aatcttgaat gtcgaaacca taaacatgtc cttctggtac ttgttcggct
     1321 aaaaataaag tgtcattgcc gttaccgcaa gttgcgtcta caacaatact ttctggtgtt
     1381 atatgttgtt taataagtgt ttttgaaaaa gggagtatac gttctaattt cattgcttca
     1441 ccttagactt gtaacgcaag ccttgataag aatttctacg tgctaattca gcatcgatgc
     1501 catttaatac ttcccattta ttaacactcc acattggacc gaccatgata tctattggac
     1561 catcaccggt aattcggtga acgatcattt cagggggaat cacttctaat tgatccacaa
     1621 ctaggtttgt gtattcttct tgagtcataa aagttaataa acctttatcg tattgtttta
     1681 ccatcggtgt accttttaac aaatgaagta aatgaatttt aataccttgt acatccattt
     1741 gtgcaacttc tttggcagta gccatcatca tgtcatagtc ttcgccaggt aagccattaa
     1801 tgatgtgtgt acatacattg atattatgct tacgtaattt tgccacacca tcataataag
     1861 ttttcatatc atgggcacga ttgattaaat cagatgttga ttgatggatt gtttgtagtc
     1921 ctaattcaac ccataagtat gttcgttgat tcaaatctgc taaatattcg acaacatcgt
     1981 ctggtagaca gtcaggacgc gtaccaatag ataatcccac aacacccggt tctttaagta
     2041 caggttcgaa tttttctttt aatacttcaa ctggtgcatg tgtatttgta aatgcctgaa
     2101 aataagcaat atattttcct tcgtgccatt tctcatgcat cttttcctta atttctttaa
     2161 attgtactgc gattgaatct gcacgattac ctgcaaagtc tccgctacct gcagcagaac
     2221 aaaatgtaca tccaccatgt gctacagtgc catcgcggtt aggacagtca aacccgccat
     2281 ccaatgcaac tttaaatatt ttttgtccaa atttattttt taaatggtaa ttccacgtgt
     2341 gataacgttt gttttcaaaa gcgtattgga aatgattgcc catatgtcat tttcctttct
     2401 ataaaaaaaa gagttctaag tacagatttt aacatatttt aatgttatag tgtttattat
     2461 agtttgacaa aaaagagaga ggaactatga aatatgaata tacctaaatc agtctggtgg
     2521 ctagtaattg gcatggcgtt aaatattact ggttccagtt ttttgtggcc tttaaataca
     2581 atttatatga aacaagaact tggaaaaagt ttaactgttg ctggtttagt gctaatgata
     2641 aattcatttg gcatggttat tggaaactta ttaggtggtt cactatttga taaattaggt
     2701 ggatacaaga cgattttaat tggaactttc acttgtcttt gtagtacaac gctacttaat
     2761 ttctttcacg ggtggccttg gtatgctgta tggcttgtaa tgttagggtt tggtggcgga
     2821 atgattattc ctgcgatata cgctatggct ggagcagtgt ggccaaatgg cggaagacaa
     2881 acgtttaatg cgatatactt agcgcaaaat attggtgtgg ctgtcggtgc tgcaatgggc
     2941 ggctttgtcg cagaatttag ctttaactat atctttttag ccaatcttat tatgtatgtt
     3001 gtgtttgcgc ttgtcgcggt aacgcaattt aatattgaaa ttaatgcgaa agttaaatat
     3061 ccaactcatt tagatattac tggtaaaaag aataaagcaa gatttatttc attagtacta
     3121 atttgtgcaa tgtttgcaat ttgttgggtt gcgtatattc aatgggagtc tacaatcgca
     3181 tcatttacac aatctattaa tatttcaatg gcacaatata gtgttttatg gacaattaac
     3241 ggaataatga ttttagtagc acaaccatta attaaaccgg ttctctatct gttaaaagga
     3301 aacttaaaga agcaaatgtt tgtcggcatc atcattttta tgttgtcgtt ctttgtcacg
     3361 agttttgccg aaaactttac aatatttgtt gtcggtatga ttattttaac ttttggagaa
     3421 atgtttgtat ggccagcagt tccaactata gccaatcagt tagcgccaga tggtaagcaa
     3481 ggacagtacc aaggttttgt gaattcagct gctacagtag gaaaagcatt tggtccattt
     3541 cttggtggtg tattagttga tgcgtttaat atgcgcatga tgtttatcgg tatgatgcta
     3601 ctacttgtat ttgcattaat attattaatg gttttcaagg agaataatac gcaacctaaa
     3661 aaaatagatg cataatgagt aaatagaatt aacgttatag acttgaaata aatgtcgtta
     3721 taacataata ttaatttgta taatttaatt tcgtttggag cttttctaca gaaagctagt
     3781 gatgctgaga gctagtgtta aggactaaat gtaaatcgta ttaattttaa attgaatgaa
     3841 tgacatctct tactattaaa atgagtgcac aatttttgtg aaatagggtg gtaacgcggc
     3901 aaatgtcgtc cctatgtaaa tagaatagtt agaggtgtct tttttattga ataggaggaa
     3961 atgtgttgaa ttacaaccac aatcaaattg aaaagaaatg gcaagactat tgggacgaaa
     4021 ataaaacatt taaaacaaat gataacttag gtcaaaagaa attttatgct ttagacatgt
     4081 ttccatatcc atcaggtgct ggtttacatg ttggacatcc tgagggctat acagcaacag
     4141 atatcatttc aagatataaa agaatgcaag gatataatgt attacatccg atggggtggg
     4201 atgcattcgg attaccagca gagcaatatg ctttagacac tggcaacgac ccacgtgaat
     4261 ttacaaagaa aaatatccaa acttttaaac gacaaattaa agaattaggg ttcagttatg
     4321 attgggatcg tgaagttaat acaacagatc cagaatacta taaatggaca cagtggattt
     4381 tcatacagtt atataacaaa ggtttagcat acgttgatga agttgcagtt aactggtgtc
     4441 cagcattagg cactgtttta tctaacgaag aagtgattga tggtgtctct gaacgtggtg
     4501 gacatccagt ttatcgtaag ccgatgaaac aatgggtact taaaatcaca gaatatgcag
     4561 atcaattatt agcagattta gatgatttag attggcctga gtctttaaaa gatatgcagc
     4621 gcaattggat tggacgttct gaaggggcca aagtttcatt tgatgtagat aatacggaag
     4681 gaaaagtaga agtatttacg actagaccag atacaatcta tggtgcatca ttcttagtct
     4741 taagtcctga acatgcatta gttaattcaa ttactactga tgaatataaa gaaaaagtaa
     4801 aagcttatca aacagaagct tctaaaaagt cagatttaga acgtacagat ttagcaaaag
     4861 ataaatcagg tgtgtttact ggtgcatatg caattaatcc tttatctggt gaaaaagtac
     4921 aaatttggat tgctgattat gtattatcaa catatggtac tggagcaatt atggcagtac
     4981 cagcgcatga tgacagagat tatgaatttg ctaaaaagtt tgatttgcca atcattgaag
     5041 tcatcgaagg tggaaatgtt gaagaagcag catacactgg tgaaggtaaa catattaatt
     5101 ctggtgaact tgatggttta gaaaatgaag cggcaattac taaagctatt caattattag
     5161 agcaaaaagg tgctggcgaa aagaaagtta attacaaatt aagagattgg ttattcagtc
     5221 gtcagcgtta ttggggcgaa ccaattcctg tcattcattg ggaagatgga acaatgacaa
     5281 ctgttcctga agaagagcta ccattgttgt tacctgaaac agatgaaatc aagccatcag
     5341 ggactggtga gtctccacta gctaatattg attcatttgt aaatgttgta gatgaaaaaa
     5401 caggtatgaa aggacgtcgt gaaacaaata caatgccaca atgggcaggt agttgttggt
     5461 attatttacg ttacatcgat cctaaaaatg aaaatatgtt agcagatcct gaaaaattaa
     5521 aacattggtt acctgttgat ttatatatcg gtggagtaga acatgcggtt cttcacttat
     5581 tatatgcaag attttggcat aaagtccttt atgatttggg tatcgtacct actaaagaac
     5641 ctttccaaaa attatttaac caaggtatga ttttaggaga aggtaatgag aagatgagta
     5701 aatctaaagg aaatgtaatc aatcctgatg atatagtaca gtctcatggt gcagatactt
     5761 tacgtcttta cgaaatgttt atgggacctt tagatgctgc aattgcatgg agtgaaaaag
     5821 gattagatgg gtctcgtcga ttcttagatc gcgtatggcg tttaatggta aatgaagatg
     5881 gaacattgag ttcaaaaatt gtaactacaa ataataaatc tttagataaa gtttataacc
     5941 aaactgttaa aaaggtaaca gaagactttg aaacattagg atttaatact gctattagtc
     6001 aattaatggt atttattaat gagtgttata aagttgatga agtttataaa ccttacattg
     6061 aaggcttcgt taaaatgtta gcacctattg caccacatat cggtgaagaa ttatggtcaa
     6121 aattaggaca tgaagagtct attacgtacc aaccttggcc aacttttgac gaagcactac
     6181 ttgtagatga tgaagtagaa atcgttgttc aagtaaatgg taaattgaga gctaaaatta
     6241 aaattgctaa agatacatca aaagaagaaa tgcaagaaat tgccttatct aatgacaatg
     6301 ttaaagcgag tattgaaggt aaagacatca tgaaagtcat cgctgttcct caaaaattag
     6361 tcaatattgt agctaaataa tgttttaagg aggactttga aatgaagtca attactacag
     6421 atgaattaaa aaacaaactt ttagaatcta aaccagttca aattgttgat gttcgtactg
     6481 acgaagaaac agcaatggga tatattccta atgcaaagtt gattccaatg gataccattc
     6541 cggataattt aaattcattt aataaaaatg aaatatatta tattgtatgt gctggtggag
     6601 ttcgaagcgc taaagttgta gaatatttag aggcaaatgg cattgatgcc gtaaatgtcg
     6661 aaggcggcat gcacgcatgg ggcgatgaag gtttggaaat aaaaagtatt taaagtagtg
     6721 acataattta aaataatatt acatttgtaa tgacaccaag taacgtttcg gttgcttggt
     6781 gttttttggt atgaattact ttctgttaca aaacattcta aagcgttctt gttatgtttt
     6841 attaagattt taattacaaa acggaaacta aattgtaata aaataaaact ttattttata
     6901 aaatgatgat gataaaattg agcgaactta aaatattgta caaaataata tagctataaa
     6961 cataatatga gggagcgtat atttttagca taattcttaa caacacagca gagaacagac
     7021 aaccaggagg aaaatgaaat gaatttgtta aagaaaaata aatatagtat taggaagtat
     7081 aaagtaggca tattctctac tttaatcgga acagttttat tactttcaaa cccaaatggt
     7141 gcacaagcct taactacgga tcaaaatgtt caaggtgagt caaatcaagc attacctgga
     7201 aactcacata atacaaatgt cgatactagt agagatatta caaatagttc gcaaaataca
     7261 cctaatcaac atacgacggc aaatgcatca acaaaccaag ctttggctaa tcatcataac
     7321 gttggtgagt caaatcaagt tgtgccaatg ccagtacagc ctagtacgtc atctgcatca
     7381 aacaataatc attctgatgc taagtcaaca gcaactgagt cagcggcgaa tacaaataat
     7441 aatttatcat caaataacaa tacattaaac gtgcctaata atacagataa caatgattca
     7501 gcgcgtcatc tgactttaaa agaaattcaa gaagatgttc gtcattcttc agataagcca
     7561 gagttagttg cgattgctga agaagcatct aatagaccga aaaaaagaag cagacgtgct
     7621 gcgccagcag atcctaatgc aacaccagca gatccaacgg ctacaccagc agacccagcg
     7681 gcaggaaacg gtagtgcacc agttgcaatt acagcgccat acacgccaac aactgatccc
     7741 aatgccaata atataggaca aaatgcacct aacgaagtgc tgtcatttga tgataacggt
     7801 attagaccaa gtacgaaccg ctctgtgcca acagtaaccg tcgttgataa tttaccaggt
     7861 tttacattaa ttaatggtgg taaagtaggg gtatttagtc atgcgatggt aagaacgagt
     7921 atgtttgatt caggagatgc taagaactat caagcacaag gcaatgtaat tgcgttaggt
     7981 cgtattagag gtaatgatgt aaatgaccat ggcgatttta atggtatcga gaaaacatta
     8041 acagtaaatc cgaattctga attaatcttt gaatttaata caatgactac taaaaactat
     8101 caaggtatga caaatttagt cattaaaaat gctgataatg atgcagttat tggtgaaaaa
     8161 gtagtcgctt atggtccgat ttggcgctta tttaaagtac ctgaaaatgt tagtcattta
     8221 aaaatacaat ttgttcctaa aaatgacgca ataacagatc cgcgtggcat ttatcaatta
     8281 cgtgatggtt ataaatacta tgactttgtt gactctatcg gtctacattc tgggtcgcat
     8341 gtctatgttg aaagacgtac aatggagcca acagcaacaa ataacaaaga attttcagtt
     8401 acaacgtcat taaagaataa tggtaacttt ggcgcttcat ttaatacaga tgattttgta
     8461 tataaaattc aattacctga aggtgttgaa tatgtaaata attcattgac taaagatttc
     8521 cagagcggta attcaggtgt tgatatcaat gattttaatg tgacgtatga cgcagcaaat
     8581 cgaattatta caattaaaag tactggtgga ggttcaggga attcaccggc acgacttatg
     8641 cctgataaaa tattggattt gaagtataag ctacgtgtga acaatgtgcc aacaccaaga
     8701 acagtaacat ttaacgatac gttaacgtat aaaacatttt cacaagattt tattaattca
     8761 cctgcagaaa gtcatacagt aagcactgaa ccgtatacaa tcgatatcat catgaataaa
     8821 gacgcactac aagctgaagt tgatagacgt attcaacaag cggattatac atttgcatca
     8881 ttagatattt ttaatgatct taaaagacgc gcacaaacaa ttttagatga aaaccgtaac
     8941 aatgtacctt taaacaaaag agtttctcag gcagatatcg attcattagc aaatcaaatg
     9001 caacatacgt taattcgaag tgttgacgct gaaaatgccg ttaatagaaa agttgatgac
     9061 atggaagatt tagttaacca aaatgatgaa ctgacagatg aagaaaaaca agcagcgatt
     9121 caagtcatcg aggaacataa aaatgaaatt attggaaata ttggtgacca aacgactgat
     9181 gatggtgtta ctagaattaa agatcaaggt atacagactt taagtagaga cactgcaaca
     9241 ccagttgtta aaccaaatgc taaacaagca atacgtgata aagctgcgaa acaaagagaa
     9301 attatcaata acacaccaga tgctactcaa gatgaaattc aagatgcatt aaatcaatta
     9361 acaacggatg aaacagatgc tattgataat gttacgaatg ctactaccaa tgctgatgtt
     9421 gaaacagcta aaaataatgg tattaatact attggagctg ttgtccctca agtaacacac
     9481 aaacaagcag caagagatgc aattaaccaa gcaacagcaa caaaaagaca acagataaat
     9541 agtaatagag aagcaacaca agaagagaaa aatgcagcat tgaatgaatt aacgcaagct
     9601 acgaaccacg ctttagagca aatcaatcaa gcgacaacca atgatgatgt ggatacagcc
     9661 aaaggtgatg gtctgaatgc cattaatcct attgcgcctg taactgttgt caagcaggca
     9721 gcaagagatg ccgtatcaca tgatgcacaa caacatatcg ctgagatcaa tgctaatcct
     9781 gatgcgactc aagaagaaag acaggcagcg attgacaaag taaatgctgc tgtagctgct
     9841 gcgaatgcta acattttaaa tgctaatacc aatgcagatg tggagcaagt gaagacaaat
     9901 gcaattcaag gtatacaagc cattgaacca gctacaaagg ttaaaacaga tgctaaaaat
     9961 gctattgatc aaagtgctga aacgcaacat aatgcgatat ttaataataa tgatgcgacc
    10021 ttagaagagc aacaagcagc acaacaattg cttgatcaag ctgtagccac agcgaagcaa
    10081 aatattaatg cagcagatac gaatcaagaa gttgcacaag caaaagatca aggtatgcaa
    10141 aatatagttg tgattcaacc agcgacacaa gttaaaacgg atgctcgtaa tactgtaaat
    10201 gaaaaagcac gtgaggtgat aacaaatatc aatgctacac ctggtgcgac tcgagaagag
    10261 aaacaagaag cgatagatcg tgtcaatgca cttaaaaata gagcattaac tgatatcggt
    10321 gtgacgtcta ctactgcgat ggtcaatagc attagagacg atgcagtcaa tcaaatcggt
    10381 gctgttcaac cgcatgtaac taagaagcaa acagctacag gtgtattaaa cgatttagca
    10441 actgctaaaa agcaagaaat taatcaaaat acaaatgcaa caactgaaga aaagcaaata
    10501 gcattaaatc aagtagacca agaattagca gctgcactta ataatataaa tcaagctgat
    10561 acaaacgcgg aagtagatca agcgcaacaa ttaggtgcac aagcaattaa tgcgattcag
    10621 ccaaatattg taaaaaaacc tgcagcatta gcacaaatca atcagcatta taatgctaaa
    10681 ttagctgaaa tcaatgctac accagatgca acagatgatg agaaaaatgc tgcaattaat
    10741 acgttgaatc aagacagaca acaagctatt gaaagtctta atcaagcgaa taccaataat
    10801 gaagtagacc aagctgcgat aacagcagaa aataatattg atgctgttca agttgacgta
    10861 gtgaaaaagc aagcagcacg agataaaatc actgctgaag tggcgaaacg tattgaagcg
    10921 gttaaacaaa cacctaatgc aactgatgaa gaaaagcagg ctgctgttaa tcaaatcaat
    10981 caacttaaag atcaagcatt taaccaaatt aatcaaaacc aaacaaatga tcaggtagac
    11041 gcaactacaa atcaagcgat aaatgctata gacaatgttg aagctgaagt agtaattaaa
    11101 ccaaaggcaa ttgcagatat tgaaaaagct gttaaagaaa agcaacagca aattgataat
    11161 agtattgatt caacagataa tgagaaagaa gttgctacac aagcattagc tagagaaaaa
    11221 gaaaaagccc ttgtagcaat tgaacaagct caaacgaacg agcaagtgaa tcaagcggca
    11281 acagatggta taactgcgat aaaaattatt caacctgaaa ctcgagttaa accagcagca
    11341 cgtgaaaaaa tcaatcaaaa agcgaatgaa ttacgtgcgc aaatcaatca agataaagaa
    11401 gcgacagcag aagaaagaca agcggcgtta gataaaatca atgatttagt tactcaagct
    11461 atgacaaata tcacgagtga tagaacagat cagcaagtta acgactcaac aaatcaagcg
    11521 cttggagaca ttgcattagt gacgcctgac catattatta gagcagctgc tagagatgca
    11581 gtaaagcaac aatatgaggc taaaaagcaa gaaatagagc aagcggaaca tgcgactgat
    11641 gaagaaaaac aagttgcttt aaatcaatta gcgaataatg aaaaacgtgc attacaaaac
    11701 atcgatcaag caatagcgaa taatgatgtg aaacgtgttg aatcaaatgg tattgctacg
    11761 ttaaaaggcg tagaaccgca cattgtggtt aaacctgaag ctcaacaagc cataaaagcg
    11821 agcgcagata atcaagtaga atctataaaa gatacaccac atgctacgac tgatgaatta
    11881 gatgaagcaa accaacaaat aaacgacaca cttaaacaag gtcaacaaga tatagacaat
    11941 acaacacaag atgtagctgt aaatgatgtt agaaatcaaa cgattaaggc aatcgaacaa
    12001 attaaaccga aagttagacg caaacgtgca gcgttggata acattgatga aagtaataat
    12061 aaccaactcg atgcaatccg aaatacgcta gatactacgc aagatgaacg aaatattgct
    12121 attgctgagt taaataaaat tgtaaatact atcaaaaatg acattgcgca aaacaaaacg
    12181 aatgcagaag tggatcaaac tgaggcggat ggtaacaata acatcaaagt gattttacct
    12241 aaagttcaag ttaaaccagc agcgcgtcat tctgttagcg caaaagctga agctcaaaat
    12301 gcacttattg atcaaagtga tttatctacc gaagaagaaa gattagctgc taaacattta
    12361 gtagatcaag cacttaatca ggctattgat cagattaatc atgctgataa gactgcacaa
    12421 gttaatcaaa atagtatcga tgctcaaaag ataatttcac aaattaaacc agcgacaaca
    12481 gttaaaacaa cagcactaca acaaattcaa aatatcgcta caaataaaat aaatttaatt
    12541 aaagcaaata atgaagcgac agatgaagaa caaaatgctg caatagcaca agtagaacaa
    12601 gcattaataa aagcgaaaca acaaattgca agtgcagtga cgaatgctga tgtagcatat
    12661 ctattgcatg atggtaaaaa tgaaattcgt gaaattgaac ctgttattaa tagaaaatca
    12721 actgcgcgag aacaattaac aacattgctc aatgataaaa aacaagcaat tgaagcgaat
    12781 gttcaagcaa cggtagaaga aagaaatagt attttagcgc agttacaaaa catttatgac
    12841 actgctattg gacaaattga tcaagatcgt agcaatgcac aagttgataa aacagcatca
    12901 ttaaatctac aaacaataca tgatttagat gtacatccta ttaaaaagcc agatgctgaa
    12961 aaaacgatta atgatgatct tgcacgtgtt acacatttag tgcaaaatta tcgaaaagta
    13021 agtgatcgta ataaggctga tgcattaaaa gctataactg cattaaaatt acaaatggat
    13081 gaagaattaa aaatagcacg cactaatgct gatgttgatg cagttttaaa acgatttaaa
    13141 gttgcattag gcgatataga agcagtaatt actgaaaaag aaaatagctt actgcgcatt
    13201 gataacattg ctcaacaaac atatgcgaaa ttcaaatcaa tcgcaacacc agaacaatta
    13261 gctaaagtaa aagcattaat tgatcaatat gttgcagatg gcaatagaat gattgatgaa
    13321 gatgcgacat taaatgacat caaacaacat acgcaattca ttgttgatga aattttagca
    13381 attaaattgc cagctgaagt gacgaatgta tcaccaaaag tggggcaacc tgctccaaaa
    13441 gtttgtacgc ctattaaaaa agaagataaa caagaagtgc acaaagttga aaaagaactt
    13501 ccaaatactg gttctgaaga aatggattta ccattaaaag aattagcgct aattacaggc
    13561 gcagcattat tagctagaag acgtactaaa aatgaaaaag aatcataatt aacgaaatga
    13621 ccttaatata acgacacttt ttagtgactc agttatatta gggtcatttt taattaaatg
    13681 aaaaagttga tctattaaag agaatcgaac caaattttat actattattc cattgatgca
    13741 tgtgcgtaat gaccggcata taatccagcg acatgtcctg ttacgagtgc acttgtaata
    13801 ttataaccac cagtataacc atgtatatct aatacttcac cacataaaaa taatcccgga
    13861 actaatttag acatcattgt tttaggttga atttctttaa gtgacacacc accacctgtg
    13921 acaaatgcct tatctatagg taatgtcccg tttaccttaa atacaaaccc tttaaacata
    13981 tttactaagt cgttcaattg ttgatttgat aagtgatgtg atgtggtatt ttcatcgatt
    14041 ccagcttgtt ccagcatgaa cagtaagtag cgctcttcaa ttagtccatg caagctgttt
    14101 ttaatgattt tatctggtgt gtccgataat aatgatgtga tgtgttgttt taattgttca
    14161 tggtttaatt caggaaatgc atcgattgcc atagaaatat gctgtgtctt ttgatttttt
    14221 tgttctttat aaacaaactg actacatctt aatgcagctg gaccactgat accaaaatga
    14281 gtgaataaca tatccatttg atgactaatg cgttttttag catttttctt aagtactgac
    14341 aattcaacat cttttaaact taaacctttt agacgattgg atttgatgaa aggttcagct
    14401 gatgtaattg gaacttcggt cgggaataac tccgtaatgg tatgacctaa atcttgtgcg
    14461 aacttataac catcaccagt tgaacctgtt tgagggacac ttgttccacc tgtagcaatc
    14521 actagcgaat ggctttcata actattattt tgagtatgta cagtgaaagt ttgatcttct
    14581 tttacttcga ttctactaac agcttcttct tctttaatcg ttacatgttg gcgttcgata
    14641 gttgtcacta atgtatcaac tacgtcttgt gctttgttgg agactggaaa catacgcccg
    14701 tgatcttctt cttttaattt aacaccccta gactcaaaaa aatctatgat ggattcatta
    14761 tcaaaaattg aaaagggact atataaaaat tttccatttc caggaatgtt cttaataatt
    14821 tcagcatatg gtaatcgatt agttacgtta catctaccgc caccagatat tttgagttta
    14881 cgacctagac ctttcttttt ttcaatgagt aacacattgc tactttgttc gcttgcagct
    14941 actgccgcca ttaagccgct aggtccgcct ccgataataa ttgtttgata catatacgct
    15001 tcctccaaat ttgttactgg acattcaatt gctattttat agtacttttt taaactttgc
    15061 tatatctctt gtgttatgag atgacaatta tgttgaatat atttataatg tgaacttcat
    15121 aaaaatgaag atgtatgtgt atgataagaa tgatttttct actgttatgc gatgttcatc
    15181 tcaaatagta gtataatgtt catatgaaat tttgtaatat tctaatcaaa atcgagtatt
    15241 caatgacaat gcgttgataa ttttgttatg ataattcatt gaatatacga caatgaaata
    15301 aagttttgtg atatattcat aataatgaaa aatgatttta cagagaaata gcttttagtt
    15361 tacaaaactt taataaacat gagataggga gattcgtaat gagtgaaagt aaagaaatgg
    15421 tgcgtggaac ctttttaatt accattagta tattaattac caaggtattg ggcgtacttt
    15481 ttatcattcc attcaactat ttaattggtg gacaagaaaa tatggcgccg ttcacatacg
    15541 cttatgcacc atataatatt gcaattgcag ttgcgacagc aggtgtacct ttagcagctt
    15601 cgaaatatgt tgcgaaatat aatgctattg gggcatataa agtcagtcag aaattttata
    15661 aatcgagttt tattgtaatg agtattaccg gtgttttagg tttcttggta ctgtatttcc
    15721 tagcacctta tatttctgaa ttaacattag ctagaaacgt acatgataaa aacggttggt
    15781 cagtcgatga tattacttgg attataagaa tcattagtat ggttgttatc tttattcctg
    15841 tattagcgac atggagaggt atattccaag gttataaatc tatggggcca acagcagtgt
    15901 cagaagtaac tgagcaaatt gcacgcgtga ttttcatatt aatcggaagt tatttagtac
    15961 taaatgtctt tgatggctct attttattag ccaatggtat tgctactttt gcagcagcag
    16021 ttggtgcgat tattggtata ttcacactct ggtattactg gagaaagcgt aagcataata
    16081 ttgatcgtat ggtcgaatct gattacacag atatagatgt gtcatatggc aagatgtata
    16141 aagaaatcat tgcttatagt attccattcg ttattgttag tttgaattat ccattattta
    16201 acttagtaga tcaatttaca cataacggtg ctttatcttt agttggtata ccttcacagt
    16261 tacaagatat attctttaat atgctaaata tgtcaactaa taaaattgtt atgattccaa
    16321 catcattaag tgctggtttt gcggtgagtt taattcctta tattacaaaa acatttgcag
    16381 aaggtcgctt acatgaaatg catcatcaaa ttagaacgtc aattggagta ttaatgttta
    16441 taactgttcc agctagtatt ggaattatgg ccttggcgca accattattc acagttttct
    16501 atggttacga tccaattgtt ttaggtcatg accctaacca tgatggcagt cgattattat
    16561 tctattatgc gcctgtagca atactaattt cactattaag tgtaacggcg tcaatgttac
    16621 aaggtataga taaacagaaa ttaacagttt atgttatttt agcttctgta gttatcaagt
    16681 tagcgttaaa ctatccatta attatgttat tccatacacc tggtgcaatt ttaagtacta
    16741 gtatcgcatt attatttgca attggatgta atttctatat tcttaaaaaa tatgcgaagt
    16801 ttaaattcag ctatagttgg attcattttg caaaaatatt cttgtattca tttattatga
    16861 tgctaggtgt agaattagta ttcttccttg caaatctatt cttagaacct actaaacttg
    16921 gttacttaat cattattatt ttaggtgtta cagtaggtat tctaatttac ggtacaatca
    16981 ctattaaaac gcgtcttgcg gacgaattct taggtgaaat tcctgaaaaa ttaagacgta
    17041 gagttaggtt tttacgatga gaatagataa atttttagca aatatgggcg tcggtacacg
    17101 taatgaggtc aaacagttac ttaaaaaagg ctttgtaaat gtcaacgaac aagtaattaa
    17161 atcagcaaaa acacatatag aaccagaaaa cgataagata tcagttcgtg gagaattaat
    17221 agaatacgtt gaaaacgtct atattatgtt aaataagcca aaaggttata tatcggcaac
    17281 tgaagatcat cattcaaaaa ccgttattga tttaatacct gaataccaac atctaaatat
    17341 ttttccggtt ggtcgtcttg ataaagatac agaagggcta ttattgataa cgaatgatgg
    17401 tgattttaat catgaattaa tgagtccaaa caaacatgtt tctaaaaaat atgaagttat
    17461 ttcagcaaat cctatcactg aagacgacat tcaagctttt aaagagggta taacactgtc
    17521 tgatggcaag gttaagcctg caattttaac ttatattgat aatcaaacgt cacacgtaac
    17581 aatttatgaa ggaaaatatc atcaagttaa acgaatgttt catagcattc aaaatgaggt
    17641 attacattta agacgtatca aaattgctga tttagaattg gacagcaatc tagattcagg
    17701 agaatatcgt ttattaactg aaaatgattt tgacaaatta aattataaat aaaagggaga
    17761 cgattgatat ggcaaaaggt aatttattta aagcgatttt aggtataggt ggcgctgtag
    17821 cagctgtact tgttacacgt aaagatagtc gtgacaagct gaaagcagaa tataataaat
    17881 ataaacaaga tcctcaaagc tataaagata atgctaagga taaagcgacg caattaggaa
    17941 caattgctaa tgaaacaatt aaagaagtaa aaacaaatcc gaaagaatat gctaatagat
    18001 taaaaaataa tccaaaagca tttttcgaag aagaaaaatc aaaatttacc gaatatgaca
    18061 ataagactga cgaaagtatt gaaaaaggta aatttgatga tgaaggtggc gtagcaccaa
    18121 ataataattt acgtatcgtc actgaagaag acttaaaaaa gaataaaaat gcattatctg
    18181 ataaagaata aggcatacaa ttaataagtt ggtattgaac tggcatatta aatatataaa
    18241 ttaaaaaagg aacaaagcag ctattaatga tttgtgtcat atcgatagca tcgttttgtt
    18301 cctttttatt attttctgac atcttattgt agtttttata tcatttcatg taaaatagaa
    18361 tttaacttat agaaaaaagg aagtcgattt cgaatgtgga aagaaaaagt tcaacaatac
    18421 gaagatcaaa tcattaatga cttaaaagga ttattagcaa ttgaaagtgt gagagatgat
    18481 gcgaaagcat cagaagacgc accagttggt ccaggtcctc gtaaggcatt agactacatg
    18541 tatgaaattg cacatagaga tggatttaca acacatgatg tggatcatat tgcaggaaga
    18601 attgaggcag gtaaaggaaa tgacgtatta ggtatcttat gtcatgttga cgttgttcct
    18661 gctggtgatg gatgggatag taatccgttt gagccggttg taacagaaga tgctatcata
    18721 gctagaggta cacttgatga caaaggtcca acaattgctg cttattatgc aattaagata
    18781 ttagaagata tgaatgtgga ttggaagaaa cgtattcata tgattattgg tacggatgaa
    18841 gaatctgatt ggaaatgtac ggatcgctat tttaaaacag aagaaatgcc aacattaggt
    18901 tttgcaccag atgcagaatt tccgtgtatt catggtgaaa aaggcattac aacatttgat
    18961 ttagttcaaa ataaacttac tgaagatcaa gatgaacctg attatgaatt aataactttc
    19021 aaatctggtg aacgttacaa catggtacct gatcatgcag aagcaagagt gcttgttaaa
    19081 gaaaatatga cagatgttat tcaagacttt gagtactttt tagaacaaaa tcatttacaa
    19141 ggtgatagta ctgttgatag tggcattcta gttttaacag ttgaaggtaa agcggttcat
    19201 ggtatggatc catctatcgg tgtgaatgcg ggtctttact tactaaaatt cttagcatca
    19261 ttaaatcttg ataataatgc acaagcgttt gtagcattta gtaatcgcta cttatttaat
    19321 tcagattttg gtgaaaagat gggaatgaaa ttccatacag atgtcatggg tgatgtgaca
    19381 actaacattg gtgttattac atatgataat gaaaatgcag gtcttttcgg tatcaattta
    19441 agatatcccg aaggatttga atttgaaaaa gctatggatc gttttgcaaa tgagattcaa
    19501 caatatggct ttgaagtgaa attaggtaaa gtccaaccac cacattatgt tgataaaaat
    19561 gatccttttg tacaaaagtt agttactgca tatagaaatc aaacaaatga tatgactgaa
    19621 ccttatacta taggtggcgg tacttatgcg agaaacttag acaagggtgt agcatttggc
    19681 gcaatgttta gtgattctga agatttaatg catcaaaaaa atgaatatat cactaaaaaa
    19741 cagttattta atgcaactag tatttattta gaagcaattt attcattatg tgtggaggaa
    19801 taatatatgg aaaaaatttt tttaaatggt gagtttgtaa gtccaagtga agcaaaggtt
    19861 tcatacaacg acagaggata cgtatttggc gatggtattt atgaatacat tcgagtatat
    19921 aatggtaagt tatttacagt aacagaacat tatgaaagat ttttacgtag tgccaatgag
    19981 attggtttag atttaaatta ttctgtagaa gaattaattg aactatctcg taaattagtt
    20041 gatatgaatc aaattgaaac tggggcaatt tatattcaag caacgcgtgg tgtagctgaa
    20101 agaaatcata gcttcccgac acctgaagta gaaccagcaa ttgttgctta tacaaagagt
    20161 tatgatcgtc cttatgatca tttagaaaat ggtgtgaatg gtgttaccgt tgaagatatc
    20221 cgttggttac gttgcgatat taaaagctta aatttattag gtaatgtttt agcgaaagaa
    20281 tatgctgtga aatataatgc agttgaagca atccaacatc gaggcgaaac tgtcactgaa
    20341 ggatcttcaa gtaatgctta tgcaattaaa gacggtgtga tttatacaca tccgattaac
    20401 aactatattc ttaatggtat tacacgaatt gtaattaaaa aaattgccga agactataac
    20461 atcccattta aagaagaaac gtttactgta gatttcttga gaaatgcaga tgaagttatt
    20521 gtttcaagta cttcagctga ggttacacct gttattaaat tagatggtga accagttaat
    20581 gatggtaaag ttggcccaat tacacgtcaa ctacaagaag gatttgaaaa gtatatagag
    20641 tcacacagta tttaaaattc tttcatcata tttttagatt aaattactta aatttatcaa
    20701 ctttcgtaag tgaattatgt tataatttaa aacgaagctt aaaagtgttg tttagaaaac
    20761 acatattagt aaaaagtgcc attttgtttc tcattttcag ttgaaatata atgataaaaa
    20821 ttataaaatt ttctatgagt tacaaatatg atgtgcatca tattttacta agtacgtaaa
    20881 tgttacagtt cataaattta tgctaaccat gaaaatggga tagcaattat tttgaaaact
    20941 agagtttatc gcctacaaaa gttacaaaaa catgtagttt tagacacggt aacattttat
    21001 gtcaagtaag tgactataga atgtatggtg tcaatgaaag acaatacgat ttaaatttag
    21061 tcgtgtaatg taggcattgg ttgaggattt aaaataatta tctggtcata aaatttgtac
    21121 cagtatggtg ttataaatta gaatatatgg ctcttgaaaa acctatttct agagccattt
    21181 tctaattgaa agtgaggtgg acgagttgga gcagttttat caattagggt ggacacttga
    21241 ttcagcaggt ggtgcatctg gtgaagcata tatggctgaa caagatggac aaaagttgtt
    21301 tttaaaacga aattcaaatc catttattgc ggcattatca gcagaaggta ttgtgcccaa
    21361 attagtatgg acgaagcgca tagaaacagg cgaggttgtt acagcacaac attggaaaaa
    21421 tggccgtgaa ctatcttcaa acgaaatgaa gcaaacaaga gttgcacatt tattaaagaa
    21481 gatacacaat tctagacctt tattaagtat gttaaagcgt atggaaatgg aacctattac
    21541 tcctgagatt atgcttaata aaattaatgc ctctttatca agagaagttt taacacatca
    21601 tattgtgaga aaatcattaa cctatttaga agagcatata ccgagtttag attcacgttt
    21661 tttcactgtt gtacatggcg atgtgaatca taataattgg ttattatctg atcgagatga
    21721 actattttta gtcgattggg aaggtgcaat gatcgcagac ccggcaattg atatcggaat
    21781 gctgctttac aactatgttc cacaacaaca atggtctgaa tggcttgaaa catatggtgt
    21841 tcaagagagc ttgaatttaa ataaacgtat gaaatggtat acggtaattc aatctatagg
    21901 tcttgtgcaa tggtatgaag agcaaaaaag atataaggat atgaacactt ggcttaaatt
    21961 cctaaatgaa gttatgaata gtaacatgtt tatttaagag gagaataaaa tatgagagtt
    22021 cgatacaaac catgggctga agattattta aaagatcatc ctgaattggt tgacatggac
    22081 ggtcaacatg cagggaaaat gactgaatgg tttgataaaa cgcaaccgat acacattgaa
    22141 attggttcgg gtatggggca gtttattaca acattagctg ctcaaaatcc tcatattaac
    22201 tatatttcaa tggaacgtga gaaaagtatc gtttataaag tattggataa agttaaagag
    22261 atgagtttaa caaatttaaa gattatttgt aatgatgcca ttgaattaaa tgaatatttt
    22321 aaagacggcg aagtttcgcg tatttatttg aacttttcag atccatggcc aaaaaatcgt
    22381 catgcaaaac gacgtttaac gtatcatacg tttttagcgt tgtatcaaca aatcttaaat
    22441 gatgaaggag atttacattt taaaactgat aacagaggac tatttgccta cagtttagaa
    22501 agtatgtctc aatttggaat gtattttaca aaaataaatc taaatttaca tcaagaagac
    22561 gatggcagta atattctaac agaatatgaa aagaaatttt cgaataaagg gtcacgtatt
    22621 tatcgtatgg aagcgaaatt ccattcacaa aaataaagca cttatgaggg tatgtacaca
    22681 tacaatcata agtgtttttt cgtactataa tggttctata gtaaaatggt tctataataa
    22741 atcggactga tagaaaaagt attttacttt tcatctgtcc gattttttga ttttgaatat
    22801 aaaaaagcgc aattgcctct gtaatttaaa gtgaccaaac ctaaactaaa ggagacaatt
    22861 gcgcctatga acaatgttat actaaatacc tttgatttaa aagaataaag cttgcatttt
    22921 acttggaaat tttaattatt aatttaaaat tacagtccga tggttatgat gtatttacat
    22981 ataatatgat tgcattaatc tttataagta gttggaagtg tattagtgtg gggcgtttcg
    23041 tttttgttcg catttatgaa tagtgatatg atgtaataaa cacatgctaa ttgtaataac
    23101 gaatacagaa agaataggtg atgttatgaa gatcggggat atatctattc attatctaaa
    23161 tggtggcaat acaaaaatgg atggcggtgc aatgtttggt gttgttccga agccgttgtg
    23221 gtcaaagcaa tacaatgcaa atgaacgaaa tcaaatcaat ttaccgacac atccaatttt
    23281 gattcaaacg gctcaatata atttgattat agatgcgggt attggtaatg gtaaattatc
    23341 tgaaaagcaa ttacgtaatt ttggagtaga tgaagaaagt catataattg ctgatttggc
    23401 aaattataat ttaacgccaa aggatattga ttatgtgcta atgacacata tgcattttga
    23461 tcatgctgcc ggtttgactg atcaagcggg acatgcaatt tttgaaaatg cgattcatgt
    23521 tgtgcaacaa gatgagtggc atgagtttat tgcacctaat ataagaagta aatcaactta
    23581 ctgggataag aataaaggcg attatagtaa caagttgatt ttattcgaaa aacattttga
    23641 accggttccg ggtatcaaga tgcaacatag tggaggtcat agctttggcc acacgattat
    23701 tacgattgaa agtcaaggag ataaagcagt tcatatgggt gatatattcc caactactgc
    23761 acataaaaat cctctatggg taacggcata tgatgattat cctatgcaat cgattcgtga
    23821 aaaagaacgc atgataccat attttattca gcaacaatat tggttcttgt tttatcatga
    23881 tgaaaactac tttgctgtaa aatacagcga tgatggtgaa aacatagatg catatatttt
    23941 acgtgaaaca ttagttgata ataactaaaa taaagatgta ttactaaaca aattttcaaa
    24001 aataaaaaaa tgagccacat ccaatcttac taattagggt gtggctcatt tttaagtttt
    24061 acgatccaaa tcaaatatgg ataaaattcg tattaacgct ctacaatgtt aatgacttca
    24121 ccagtatatg catctgcata aaaatcataa tgaatatttt gaccattttt aatagttgta
    24181 attccacctt gataaactaa acggtattta tcagtttcag gatgaacgaa tggttcataa
    24241 acgatatatg agcctttgac attcataaaa tatgatttta cttcattaag tactttaacg
    24301 ggattatagc gtttacgatt aataaattgg atgattgaaa tggtagaaat aattacaatg
    24361 gctactgcaa ttattgttgg aattatatat ttcagtttag tcatcattta agctcccttg
    24421 atttcaaatt catatcatta gtttaccata ttgaagatga tataataact tataaggagt
    24481 gagaactttt atgaacataa ataaaaaagt aacattacaa cgaattcaaa ctttaactga
    24541 gcttcatggg gcaccaggtt ttgaagaaga agtaaaaaat tatatgactc agcaaatggc
    24601 gccgtacgta gatgaattta ttgaaaatcg tatgggtgga ttttttggtg tgaaaaaatc
    24661 taaaaatcca aatgcaaaac gtgtaatgat tgcagcacat atggatgaaa tcggatttat
    24721 gattacaaat atcactaaaa atggaatgat tcaattcaca aatttaggtg gtgttgcaaa
    24781 tgatatttgg caaggacaac gcttagtaat taaaaataga aatggcgata aaattatcgg
    24841 tgttgtttct aatataccta aacattttcg tactggtagt gaaggtgcac cggaaattaa
    24901 agatttaaca ttagatatag gtgctcaaaa tgaagatgag gtgcgtgagc gcggaataga
    24961 tataggagat acaattgtac ctcacacgcc attcacacag ttatctgaac atcgatatag
    25021 tgctaaagca tgggataatc gttatggttg tgtcttggca attgaaatac tagaattatt
    25081 aaaagatata gaattagatg tagacttgta tgttggcgca aatgttcaag aagaggttgg
    25141 attacgaggt gcgaaagcat ctgcagagat gatagaccca gacgttgcat ttgtagtcga
    25201 ttgttcacct gccaatgacg ttaaaggaaa ccaaccatta tctggtgaac ttggtaaagg
    25261 gacgttaatt cgcataaaag acggtacaat gattttaaag cctgtattta gagattattt
    25321 attaaagtta gtagaagcac atgacattga acatcaatac tatatgtcac caggtggaac
    25381 agatggtgga gaaattcata aagctaatat tggtattccg actgcagtta ttggtgtatg
    25441 tgcacgatat attcatagta cagactcagt atttgatata agagactatt ttgcagctag
    25501 atctttactt tcagaagcca tttgtaattt agataataat caaatagaaa cattacaata
    25561 taaataatcg ggtaataaca actattatct ctaaatagtt atatataatc attaattaag
    25621 gagacataaa aatgaaacaa cttgaatcag aacaacaatt tgaatcttta aaacaaggtg
    25681 ctacagtgtt tgaattcact gcaggctggt gtccagattg tagagtgata gaaccagatt
    25741 taccggaatt agaagcgaga tatcctatgt ttgacttcgt atcagtagac cgtgacaaat
    25801 ttatggatat ttgtattgaa aatggtatta tggggattcc aagttttcta gtatataaaa
    25861 atggtgaact gcttggaagt tatattggaa aagaacgaaa atcaattgaa aagatagatg
    25921 catttttagc tcaatacgtg taatttagac tagagaaaaa cggggtaata ctcgtttttc
    25981 tctgttacta tgtgttgatt tattgtaaac tattataagg tgcgaaatta ggagtgttac
    26041 atatgaatac ctttcaaatg agagataaat taaaggaacg tttaagccat ttagacgttg
    26101 attttaaatt taatcgtgaa gaagaaactt tgcgtattta tcgaacagat aataacaaag
    26161 gtatcacgat taaacttaac gctatagtcg caaaatatga agataaaaaa gaaaaaattg
    26221 tagatgaaat tgtttattac gttgatgaag ctattgcaca aatggcagat aaaacccttg
    26281 agagtatatc atctagtcaa attatgcctg tcattagagc gactagcttt gataaaaaaa
    26341 ctaaacaagg tgttcctttt atctatgatg agcatagtgc agaaacagca gtttattatg
    26401 cagtcgattt agggaaatca tatcgtctaa ttgacgaaag catgttagag gatttgaagt
    26461 taactgaaca acaaataaga gaaatgtctc tgtttaatgt tagaaaattg tcaaattcat
    26521 atacgactga tgaagtaaaa ggtaatattt tttattttat taactcaaat gacgggtatg
    26581 atgcaagtag gatactaaat actgcatttt taaatgaaat tgaggcacaa tgtcaaggcg
    26641 aaatgctcgt agcagtgcca caccaagatg tgttaattat tgcagatata cgcaataaaa
    26701 caggatatga tgtgatggca catttaacaa tggaattttt cactaaaggt ctagttccaa
    26761 ttacatcatt atcctttgga tataaacagg gtcatcttga accgatattt attttaggta
    26821 aaaataataa acaaaaaaga gatccaaacg tgattcagcg tttagaagca aatcgtcgta
    26881 aatttaataa agataaatag aaataattgg ataaggagtt ttgtcataat gaatttattt
    26941 tacaatccta aatatgtagg agatgtcgca tttttacaaa ttgaaccagt tgaaggtgaa
    27001 ttaaactaca ataaaaaagg taatgttgtt gaaattacta atgaaggtaa tgttgtaggt
    27061 tataatattt ttgaaatttc aaaagatata acaattgaag aaaaaggtca tattaaatta
    27121 actgatgaac ttgtaaatgt attccaaaag cgtatttcag aagctggttt tgattataaa
    27181 ttaaatgctg atctatcacc gaaatttgta gttggctacg ttgaaactaa agacaaacat
    27241 cctgatgcag ataaattaag tgtactaaat gtaaacgttg gaaatgacac attacaaatt
    27301 gtatgtggcg cgcctaacgt tgaagctgga cagaaagttg ttgttgctaa agtaggtgca
    27361 gtgatgccta gcggtatggt aattaaagat gctgaattac gtggtgttgc ctcaagcggt
    27421 atgatttgtt caatgaaaga attgaattta cctaatgcac ctgaagaaaa aggtattatg
    27481 gtattaaatg acagctatga aattggacaa gcattttttg aataattaag gaaggtagtg
    27541 aaaatatgag ctggtttgat aaattattcg gcgaagataa tgattcaaat gatgacttga
    27601 ttcatagaaa gaaaaaaaga cgtcaagaat cacaaaatat agataacgat catgactcat
    27661 tactgcctca aaataatgat atttatagtc gtccgagggg aaaattccgt tttcctatga
    27721 gcgtagctta tgaaaatgaa aatgttgaac aatctgcaga tactatttca gatgaaaaag
    27781 aacaatacca tcgagactat cgcaaacaaa gccacgattc tcgttcacaa aaacgacatc
    27841 gccgtagaag aaatcaaaca actgaagaac aaaattatag tgaacaacgt gggaattcta
    27901 aaatatcaca gcaaagtata aaatataaag atcattcaca ttaccatacg aataagccag
    27961 gtacatatgt ttctgcaatt aatggtattg agaaggaaac gcacaagtca aaaacacata
    28021 atatgtattc taataataca aatcatcgtg ctaaagattc aactccagat tatcacaaag
    28081 aaagtttcaa gacttcagag gtaccatcag ctatttttgg cacaatgaaa cctaaaaagt
    28141 tagaaaatgg tcgtatccct gtaagtaaac cttcagaaaa agttgagtca gataaacaaa
    28201 aatatgataa atatgtagct aagacgcaaa cgtctcaaaa taaacaatta gaacaagaaa
    28261 aacaaaatga tagtgttgtc aaacaaggaa ctgcatctaa atcatctgat gaaaatgtat
    28321 catcaacaac aaaatcaatg cctaattatt caaaagttga taatactatc aaaattgaaa
    28381 atatttatgc ttcacaaatt gttgaagaaa ttagacgtga acgagaacgt aaagtgcttc
    28441 aaaagcgtcg atttaaaaaa gcgttgcaac aaaagcgtga agaacataaa aacgaagagc
    28501 aagatgcaat acaacgtgca attgatgaaa tgtatgctaa acaagcggaa cgctatgttg
    28561 gtgatagttc attaaatgat gatagtgact taatagataa tagtacagat gctagtcagc
    28621 ttcatacaaa tggcatagag aatgaaactg tatcaaatga tgaaaataaa caagcgtcaa
    28681 tacaaaatga agacactaat gacactcatg tagatgaaag tccatacaat tatgaggaag
    28741 ttagtttgaa tcaagtatcg acaacaaaac aattgtcaga tgatgaagtt acggtttcga
    28801 atgtaacgtc tcaacatcaa tcagcactac aacataacgt tgaagtaaat gataaagatg
    28861 aactaaaaaa tcaatccaga ttaattgctg attcagaaga agatggagca acgaataaag
    28921 aagaatattc aggaagtcaa atcgatgatg cagaatttta tgaattaaat gatacagaag
    28981 cagatgagga tactacttca aatatcgaag ataataccaa tagaaacgcg tctgaaatgc
    29041 atgtagacgc tcctaaaacg caagagcacg cagtaactga atctcaagtt aataatatcg
    29101 ataaaacggt tgataatgaa attgaattag caccgcgtca taaaaaagat gaccaaacaa
    29161 acttaagtgt caactcattg aaaacgaatg atgtgaatga tggtcatgtt gtggaagatt
    29221 caagcatgaa tgaaatagaa aagcataacg cagaaattac agaaaatgtg caaaacgaag
    29281 cagctgaaag tgaacaaaat gtcgaagaga aaactattga aaacgtaaat ccaaagaaac
    29341 agactgaaaa ggtttcaact ttaagtaaaa gaccatttaa tgttgtcatg acgccatctg
    29401 ataaaaagcg tatgatggat cgtaaaaagc attcaaaagt caatgtgtct gaattaaagc
    29461 ctgtacaaag taaacaagct gtgagtgaaa gcaagcctgc gagtcaagcc gcaccatcat
    29521 caagctctga ttcacaagag tcaaacacaa atgcatataa aacaaataat atgacatcaa
    29581 acaatgttga gaacaatcaa cttattggtc atgcagaaac agaaaatgat tatcaaaatg
    29641 cacaacaata ttcagagcag aaaccttctg ctgattcaac tcaaacggaa atatttgaag
    29701 aaagccaaga tgataatcaa ttggaaaatg agcaagttga tcaatcaact tcgtcttcag
    29761 tttcagaagt aagcgacata actgaagaaa gcgaagaaac aacacatcca aacaatacta
    29821 gtggacaaca agataatgat gatcaacaaa aagatttaca gccttcattt tcaaatcaaa
    29881 atgaagatac agctaatgaa aatagacctc ggacgaacca acaagatgtt gcaacaaatc
    29941 aagctgtaca aacatctaag ccgatgattc gtaaaggccc aaatattaaa ttgccaagtg
    30001 tttcattact agaagaacca caagttattg agccggacga ggactggatt acagataaaa
    30061 agaaagaact gaatgacgca ttattttact ttaatgtacc tgcagaagta caagatgtaa
    30121 ctgaaggtcc aagtgttaca agatttgaat tatcagttga aaaaggtgtt aaagtttcaa
    30181 gaattacggc attacaagat gacattaaaa tggcattggc agcgaaagat attcgtatag
    30241 aagcgcctat tccaggaact agtcgtgttg gtattgaagt tccgaaccaa aatccaacga
    30301 cggtcaactt acgttctatt attgaatctc caagttttaa aaatgctgaa tctaaattaa
    30361 cagttgcgat ggggtataga attaataatg aaccattact tatggatatt gctaaaacgc
    30421 cacacgcact aattgcaggt gcaactggat cagggaaatc agtttgtatc aatagtattt
    30481 tgatgtcttt actatataaa aatcaccctg aggaattaag attattactt atcgatccaa
    30541 aaatggttga attagctcct tataatggtt tgccacattt agttgcaccg gtaattacag
    30601 atgtcaaagc agctacacag agtttaaaat gggccgtaga agaaatggaa cgacgttata
    30661 agttatttgc acattaccat gtacgcaata taacagcatt taacaaaaaa gcaccatatg
    30721 atgaaagaat gccaaaaatt gtcattgtaa ttgatgagtt ggctgattta atgatgatgg
    30781 ctccgcaaga agttgagcag tctattgcta gaattgctca aaaagcgaga gcatgtggta
    30841 ttcatatgtt agtagctacg caaagaccat ctgtcaatgt aattacaggt ttaattaaag
    30901 ccaacatacc aacaagaatt gcatttatgg tatcatcaag tgtagattcg agaacaatat
    30961 tagacagtgg tggagcagaa cgcttgttag gatatggcga tatgttatat cttggtagcg
    31021 gtatgaataa accgattaga gttcaaggta catttgtttc tgatgacgaa attgatgatg
    31081 ttgttgattt tatcaaacaa caaagagaac cggactatct atttgaagaa aaagaattgt
    31141 tgaaaaaaac acaaacacaa tcacaagatg aattatttga tgatgtttgt gcatttatgg
    31201 ttaatgaagg acatatttca acatcattaa tccaaagaca tttccaaatt ggctataata
    31261 gagcagcaag aattatcgat caattagagc aactcggtta tgtttcgagt gctaatggtt
    31321 caaaaccaag ggatgtttat gttacggaag cagatttaaa taaagaataa ttatgagtaa
    31381 ggagttttat ataatgacac actatcattt tgtcggaatt aaaggttctg gcatgagttc
    31441 attagcacaa atcatgaatg atttaggaca tgaagttcaa ggatcggata ttgagaacta
    31501 cgtatttaca gaagttgctc ttagaaataa ggggataaaa atattaccat ttgatgctaa
    31561 taacataaaa gaagatatgg tagttataca aggtaatgca ttcgcgagta gccatgaaga
    31621 aatagtacgt gcacatcaat tgaaaataga tgttgtaagt tataatgatt ttttaggaca
    31681 gattattgat caatatactt cagtagctgt aactggtgca catggtaaaa cttctacaac
    31741 aggtttatta tcacatgtta tgaatggtga taaaaagact tcatttttaa ttggtgatgg
    31801 cacaggtatg ggattgcctg aaagtgatta tttcgctttt gaggcatgtg aatatagacg
    31861 tcacttttta agttataaac ctgattacgc aattatgaca aatattgatt tcgatcatcc
    31921 tgattatttt aaagatatta atgatgtttt tgatgcattc caagaaatgg cacataatgt
    31981 taaaaaaggt attattgctt ggggtgatga tgaacattta cgtaaaattg aagcagatgt
    32041 tccaatttat tactatggat ttaaagattc ggatgacatt tatgctcaaa atattcaaat
    32101 tacggataaa ggtactgctt ttgatgtgta tgtggatggt gagttttatg atcacttcct
    32161 gtctccacaa tatggtgacc atacagtttt gaatgcatta gctgtaattg cgattagtta
    32221 tttagagaag ctagatgtta caaatattaa agaagcatta gaaacgtttg gtggtgttaa
    32281 acgtcgtttc aatgaaacta caattgcaaa tcaagttatt gtagatgatt atgcacacca
    32341 tccaagagaa attagtgcta caattgaaac ggcacgaaaa aaatatccac ataaagaagt
    32401 tgttgcagta tttcaaccac acactttctc tagaacacaa gcatttttaa atgaatttgc
    32461 agaaagttta agtaaagcag atcgtgtatt cttatgtgaa atttttggat caattagaga
    32521 aaatactggt gcattaacga tacaagattt aattgataaa attgaaggtg catcgttaat
    32581 taatgaagat tctattaatg tattagaaca atttgataat gctgttattt tatttatggg
    32641 tgcaggtgat attcaaaaat tacaaaatgc atatttagat aaattaggca tgaaaaatgc
    32701 gttttaatat gtttataata gagtagtatg ggtatttatt attaatgaca ttattacatg
    32761 ttaattagga ggcgttttta atggattgga ttttaccaat tgctggaatt atcgctgcga
    32821 ttgcattctt aattttatgt atcggtatcg tagctgtatt aaattctgtt aagaaaaact
    32881 tagattatgt tgcaaaaaca cttgacggtg tagaaggtca agttcaaggt attactcgtg
    32941 aaacaacaga tttacttcat aaagtaaacc gtttaactga ggatatccaa ggtaaagtag
    33001 atcgtttaaa ctcagttgta gatgctgtta aaggtatcgg tgactcagta caaacgttaa
    33061 acagctctgt agatcgtgta acaaattcaa ttacacataa tatttctcaa aatgaagata
    33121 aaatctcaca agttgttcaa tggtcaaatg ttgcaatgga aattgcagac aaatggcaaa
    33181 atagacacta ccgtcgtgga agtgcaaatt acaaagctaa taatgtagca actgatgcaa
    33241 atcatagcta tacttctcga gtagataaat aattaataat taaacaaatg cacttaaatg
    33301 aggttgttac ttatttaagt gcatttgtta taggaggata tacaaatgac gcagcaacaa
    33361 aataataaaa gaacattaaa aaataaacac acttatcata atgaactact accgaaccgt
    33421 aaagattttg ttgttagttt tataactggc gcgcttgttg gttcagcttt aggcttgtat
    33481 tttaaaaata aagtttatca aaaagcagat gatttaaaag tcaaagaaca agaactgtcg
    33541 caaaagtttg aagaaagaaa aacgcaactt gaagaaacgg ttgcctttac aaaagaacgt
    33601 gttgaaggat ttttaaacaa atctaaaaat gagcaagcgg cattaaaagc acaacaagca
    33661 gcaataaaag aagaagcaag tgcaaataat ttaagtgata catcacaaga ggcacaagag
    33721 attcaagaag ctaaaaaaga agcacaagca gaaacggata aaagtgcaga agtatcaaat
    33781 aaagaatcaa aagcagtggc attaaaagca caacaagcag caataaaaga agaagcaagt
    33841 gtaaataatt taagtgatac atcacaagag gcacaagaga ttcaagaagc taaaaaagaa
    33901 gcacaagcag aaacagataa aagtgcagct gtatcaaatg aagaatcaaa agcagtggca
    33961 ttaaaagcac aacaagcagc aataaaagaa gaagcaagtg caaataattt gagtgataca
    34021 tcacaagagg cacaagaaat tcaagaagct aaaaaagaag cacaagcaga aacagataaa
    34081 agtgaagctg tatcaaatga agaatcaaaa gcagtggcat taaaggtatc gaaagaagag
    34141 tcacaagctg aaagattagc aaacgctgca aaacagaagc aagctaaatt aacaccaggt
    34201 tcaaaagaga gtcaattaac tgaagcgtta tttgcagaaa aaccagttgc taaaaatgac
    34261 ttgaaagaaa ttcctcaatt aattactaaa aagaatgatg tatcagaaac agttaataca
    34321 gataataaag acactgtaaa acaaaaagaa gctaaatttg aaaatggtgt tattacacgt
    34381 aaagctgatg aaaaaacaac taataataca gatgttgaca agaaatcagg taaacaatct
    34441 aaaaaaacaa caccttcaaa taaacgaaat gcatcaaaag catctacaaa taaaacttca
    34501 ggtcagaaaa agcaacataa taagaaatca tcacaaggtg ctaagaaaca aagtagttca
    34561 agtaagtcaa ctcaaaagaa taatcaaact agtaataaga attcaaaagc aacaaatgct
    34621 aaatcatcaa atgcatcaaa aaaatcaaat gcaaaagttg aaaaagctaa aagtaaaata
    34681 gagaagcgta catttaatga ctaagcatac taaaatcgtt taataatcat tcatagcagt
    34741 aagctatgta ttatatttat aaaaattgaa tttcaaaata aaaggtaggc attcaggtgc
    34801 ttaccttttt tgatatcatc agtttatttt gaaaggcaac gcgatcattc catgtattta
    34861 ttttgtttgt aacatcgtta gattacaata gtgatattgc acattttaag ctgaagatgg
    34921 aaaaatattc gataatcaaa taaacaatga atcttagtaa ttacaatgac gttcactaat
    34981 tcaaatatag ctgaatatgt tggtgagtga tgttcactat agatttatat taatatacaa
    35041 aggttgttaa attttattaa gcgttaggtt gaatgtatga gaattttaga tttataatag
    35101 aagatagaaa ccaaaatttt tcttaaaagc agtaatgttg actcaaaata agctataatc
    35161 atgacactta tttaattgat taacatgtgc taataaatat caatatagaa tataactttc
    35221 aaacaatgac tgagaaaatc gaaatgtcag tcaagcatca tatagttaga aaattaatta
    35281 ttttctgtca atttagggtt gaactataca tatgatattg ttagaatatt ttttaacatt
    35341 atattttatt gctttaaagt ggaatatact tgaaataatt cgtagaggtg agtaaggatg
    35401 agtaataaat tagaatcata cagaagtgag attgtctcac tgaatcatca aattttagac
    35461 ttattatcta aacgtggtga actagcacaa aaaattgggg aagaaaaatt aaaacaaggt
    35521 acacgtatct atgatccaca acgtgaaaaa gaaatgctta acgacttaat cgatagtaac
    35581 aaaggaccat tcaacgataa tactattaag caattattta aagaaatttt caaagcctct
    35641 acagatttac aaaaatctga aaatgaaaaa catttatatg tatcacgtaa gttgaaacct
    35701 gaagatacga ttgtaacatt tgataatggg ggcattattg gagacggcaa taaatcattt
    35761 gtatttgggc catgttcagt tgaatcattt gaacaagttg aagctgttgc taaaaactta
    35821 catgctaaag gtgaaaaatt tattcgtggc ggtgcattta aaccacgtac atcaccatat
    35881 gatttccaag gtttaggtgt tgaaggtctt aaaatactta aacaaattaa agataaatat
    35941 gatttaaatg ttgtcagtga aatcgtaaat ccaaatgatt ttgaagtggc tgatgagtat
    36001 ttagacgtat tccaaattgg tgcacgtaat atgcaaaact tcgagttatt aaaagaagct
    36061 ggccgtacga aaaagcctat tctattaaaa cgtggtttat ctgctacaat cgaagagttt
    36121 gtttatgcag ctgaatacat tgcttcacaa ggtaatcaaa acattatttt atgtgaacgt
    36181 ggaatccgaa cttatgaaaa ggctacacgt aacactttag atatttcagc agtaccaatt
    36241 ttaaaacaag gtacgcactt accagtcatg gtagatgtta cgcatagtac aggtcgtaaa
    36301 gatatcatgt taccaactgc gaaagcagca ttagcagtag gtgctgatgg cgttatggct
    36361 gaggtgcatc cagatccatc tgttgcactt agtgatgcgg gtcaacaaat ggatttagat
    36421 gaattccaag cattttatga tgaattaaag cctttgtctg atttatataa cgctaaaaag
    36481 ttaaaataat attccaagga aactatagac tacttaacta atatgtcatg ttgaagtaga
    36541 atattatctt tgaatcgaca attttaaact tgtagccatt ctaagagtat attactttta
    36601 gagtggctat tattttttgt atagaaataa aggtgtactg cacttaacga ttgttataat
    36661 acttcaacac ttgttcaatt tcacaattat taaagattat gactgattgc agtaattaaa
    36721 attataacta tgaattatct gtaaatataa tagattcaca catttgttac tgaaatgtga
    36781 acatttttca acaaatgcaa ttggtatttg aaaaggcttt ctcaaaatat tacaattaaa
    36841 aatgaaaaaa gtttatataa aattaaaata tatcgttcgt tatcatttag cgtttgtttt
    36901 tatttcaagc ttttcgctaa atttttccaa acaaaaatat gttactgtaa attaaaatat
    36961 ggtaaactat gaaaatgaaa
//
LOCUS       DAPSKH010000023        36352 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPSKH010000023 DAPSKH010000000
VERSION     DAPSKH010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36352
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.023"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(260..322)
                     /locus_tag="RPH49_001226"
     CDS             complement(260..322)
                     /locus_tag="RPH49_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014532416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-4"
                     /protein_id="HDY5124392.1"
                     /translation="MAIVGTIIKIIKAIIDIFAK"
     gene            complement(386..454)
                     /locus_tag="RPH49_001227"
     CDS             complement(386..454)
                     /locus_tag="RPH49_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-3"
                     /protein_id="HDY5124393.1"
                     /translation="MEFVAKLFKFFKDLLGKFLGNN"
     gene            complement(506..571)
                     /locus_tag="RPH49_001228"
     CDS             complement(506..571)
                     /locus_tag="RPH49_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-2"
                     /protein_id="HDY5124394.1"
                     /translation="MGIIAGIIKFIKGLIEKFTGK"
     gene            complement(603..668)
                     /locus_tag="RPH49_001229"
     CDS             complement(603..668)
                     /locus_tag="RPH49_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin PSM-alpha-1"
                     /protein_id="HDY5124395.1"
                     /translation="MGIIAGIIKVIKSLIEQFTGK"
     gene            1189..2673
                     /locus_tag="RPH49_001230"
     CDS             1189..2673
                     /locus_tag="RPH49_001230"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH dehydrogenase subunit 5"
                     /protein_id="HDY5124396.1"
                     /translation="MLSFQLLFSLFVIALIIALISGLLFLAPVMPMRYIKLHLYILVM
                     PVLFAVIGFFGIHGQHVLGPFKIDRLSWLLAGFVMALGFIIQKFSMRYLLGDHHYRHY
                     FPLFTAITSFASLAWMSEDLRLMALCWGMTLLCLTLLMNVNRFWKVPRESAKLSSMTF
                     LCGWLAFVGAIVTIYIATGEWRVPQHMSNSTWSLLTNVLLVLAVMIPAAQFPFHRWLI
                     ESVTAPTPVSAIMHAGIVNAGGVILTRFAPIFDNGFALSLLLILSSISVLLGSGISLV
                     QVDYKRQLVGSTMSQMGFMLVQCALGVYSAAIIHLILHGIFKATLFLQSGSIVKRFNI
                     PKQASAKDAYGWIVMGRVLAIIVAFLFWMSSDRSAYEVLSALILAWSLLVSWNQMVAF
                     SKGRMARLVGMILIAIVTFIYIITHNYFYDVLRNITTHATTPPTVSVIISVVILIFGS
                     LLSIWVARHRYSKGFAVLYVWLVNLGEARSKAIESHPNYLKKYL"
     gene            2686..5391
                     /locus_tag="RPH49_001231"
     CDS             2686..5391
                     /locus_tag="RPH49_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbcC family protein"
                     /protein_id="HDY5124397.1"
                     /translation="MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDV
                     AKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHHYNIPQHYINLYID
                     NIKTLKDVPTSYMNHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLS
                     EQVNRQMIKWTKIYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPN
                     DPEMTIESVLTHFSIAQEDYQACVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAI
                     RLVVEQLLVGDEFKSVTKDCESRSENWFKQTVASWCYYSDMPSDVLLQHDVNEIQTFI
                     HFAATMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNANQP
                     HSVLLNDTQAVDENNSELNQMGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGF
                     FGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLM
                     KNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFD
                     RTSDLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGAC
                     GGASSGFNAKLLAMICNRPNVRQGLKQAGVVIPETTVFAAAEHHTSTDTLAWVYVPDT
                     LSALALDAYESLNDAMPMISEHANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEW
                     GLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTLLNTIISGPALVAQWINLQ
                     YYASTVAPHFYGSGNKATQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRL
                     LVVVQAPDYVVARLLANNDHFARKVSNHWLRLMSVNEEGRFKSWI"
     gene            5553..5915
                     /locus_tag="RPH49_001232"
     CDS             5553..5915
                     /locus_tag="RPH49_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2294 domain-containing protein"
                     /protein_id="HDY5124398.1"
                     /translation="MKRTKGEIEAEISKAITQWEKDFLGRGSLSVKSDILRDMVIISL
                     QGILTPAEYRVCSTNEGLLNIKRTRSELVESGEQDLNDIILKITGIKVMSFHSDLSTV
                     TGERIIVFKLEDNLEKHI"
     gene            complement(6144..6560)
                     /locus_tag="RPH49_001233"
     CDS             complement(6144..6560)
                     /locus_tag="RPH49_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124399.1"
                     /translation="MLSIISMCHKFHFTDNIKIIKFILLCILQIKHCIIEITIFCYFQ
                     FSTIYSYYTEGVRRINRVIFVYIALIITLVRFFTPIHPSFSNLIYWIFVLYFIPIILC
                     VIGFKAEKLIATMVIIPNFLGILYRLYAYVTHILFM"
     gene            6598..7272
                     /locus_tag="RPH49_001234"
     CDS             6598..7272
                     /locus_tag="RPH49_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDY5124400.1"
                     /translation="MIDKKLTSPKMTVPLFLIALIVFIGMFYSVVTNQEWLKNIDMGS
                     LTWFTDYFGEPQRQYVNNLFNYYMTFSAEIGDVKGVVLISIIITIILFIKQRHLAVWF
                     VTYLVSGVIMNKLIKDTVLRPRPYNHLAVDTGFSFPSGHSNASTLLYFALMIIIISLA
                     AKTITKVLSALVMGILWLSILFCRLYFHAHYFSDVIGGTSLAIIWVALFLMVYPYFIN
                     HRRQRV"
     gene            7309..8043
                     /locus_tag="RPH49_001235"
     CDS             7309..8043
                     /locus_tag="RPH49_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase"
                     /protein_id="HDY5124401.1"
                     /translation="MRIKTPSPSYLKGTNGHAILLLHSFTGTNRDVKHLAAELNAQGF
                     SCYAPNYPGHGLLLKDFMTYNVDDWWEEVEKAYQFLVNEGYESISATGVSLGGLMTLK
                     LAQHYPLKRIAVMSAPKEKSDDGLIEHLVYYSQRMSNILNLDQQASSAQLAAIDDYEG
                     EITKFQHFIDDIMTNLNVIKMPANILFGGKDAPSYETSAHFIYEHLGSVDKELNGLKD
                     SHHLMTHGEGRDILEENVIRFFNALT"
     gene            8172..8285
                     /locus_tag="RPH49_001236"
     CDS             8172..8285
                     /locus_tag="RPH49_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124402.1"
                     /translation="MGIVPEVVMWRDVGDIDGVVCGEILAYVYSVEPENLM"
     gene            8450..9787
                     /locus_tag="RPH49_001237"
     CDS             8450..9787
                     /locus_tag="RPH49_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="HDY5124403.1"
                     /translation="MKRQQSQWKSSTGFILASAGSAIGLGAMWKFPYMAGIYGGGAFL
                     AMFLIFTIFVGLPLLIMEFTVGKMGRTYTTQIYSKLTGKKWLNIIGWNGNLAVFILFG
                     FYSVIGGWIVIYIGQVLWQLVIFQRINHLQEMNFEAVISNPWLTVLGQGIFIFATMII
                     VMLGVEKGLEKASKVMMPLLFVFLIIIVIKSLTLDGALEGVKFILQPRVSEITADGIL
                     FALGQSFFTLSLGTTGMITYASYASKDMTIKSSAISIVVMNIFVSVLAGLAIFPALHS
                     FGYEPQEGPGLLFKVLPMVFSQMHLGTLFYLGFLVLFLFAALTSSISLLELNVSNFTK
                     NDNTKRKKVAVIGSILVFIISIPATLSFGILKDVRFGAGTIFDNMDFIVSNVLMPLGA
                     LGTTLVVGQLLDKKLLQQYFGKDRFRLFSGWYYLIKYAMPVVIILVFIVQLFS"
     gene            10004..10909
                     /locus_tag="RPH49_001238"
     CDS             10004..10909
                     /locus_tag="RPH49_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000634108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDY5124404.1"
                     /translation="MITYDLIGNTPLVLLEHYSDDKVKIYAKLEQWNPGGSVKDRLGK
                     YLVEKAIQEGRVRAGQTIVEATAGNTGIGLAIAANRHHLKCKIFAPYGFSEEKINIMI
                     ALGADVSRTSQSEGMHGAQLAARSYAEKYGAVYMNQFESEHNPDTYFHTLGPELTSAL
                     QQIDYFVAGIGSGGTFTGTARYLKQHHVQCYAVEPEGSVLNGGPAHAHDTEGIGSEKW
                     PIFLERRLVDGIFTIKDQDAFRNVKSLAINEGLLVGSSSGAALQGALNLKAQLSEGTI
                     VVVFPDGSDRYMSKQIFNYEENDYE"
     gene            10902..12044
                     /locus_tag="RPH49_001239"
     CDS             10902..12044
                     /locus_tag="RPH49_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional cystathionine
                     gamma-lyase/homocysteine desulfhydrase"
                     /protein_id="HDY5124405.1"
                     /translation="MNKKTKLIHGGHTTDDYTGAVTTPIYQTSTYLQDDIGDLRQGYE
                     YSRTANPTRSSVESVIAALENGKHGFAFSSGVAAISAVVMLLDKGDHIILNSDVYGGT
                     YRALTKVFTRFGIEVDFVDTTHTDSIVQAIRPTTKMLFIETPSNPLLRVTDIKKSAEI
                     AKEHGLISVVDNTFMTPYYQNPLDLGIDIVLHSATKYLGGHSDVVAGLVATSDDKLAE
                     RLAFISNSTGGILGPQDSYLLVRGIKTLGLRMEQINRSVIEIIKMLQAHPAVQQVFHP
                     SIESHLNHDVHMAQADGHTGVIAFEVKDTESAKQLIKATSYYTLAESLGAVESLISVP
                     ALMTHASIPADIRAKEGITDGLVRISVGIEDTEDLVDDLKQALDTL"
     gene            12338..13363
                     /locus_tag="RPH49_001240"
     CDS             12338..13363
                     /locus_tag="RPH49_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HDY5124406.1"
                     /translation="MIEFRQVSKTFNKKKQKIHALKDVSFKVNRNDIFGVIGYSGAGK
                     STLVRLVNHLEAASSGQVLVDGHDITNYSEKGMREIKKDIGMIFQHFNLLNSATVFKN
                     VAMPLILSKKSKTEIKQRVTEMLEFVGLSDKKDQFPDELSGGQKQRVAIARALVTNPK
                     ILLCDEATSALDPATTASILTLLKNVNQTFGITIMMITHEMRVIKDICNRVAVMEKGQ
                     VVETGTVKEVFSHPKTTIAQNFVSTVIQTEPSTSLIRRLNDEQVGDFKDYKIFVEETQ
                     VTQPIINDLIQICGREVKILFSSMSEIQGNTVCYMWLRFNMDQQFDDTAINQYFKEKN
                     IQFEEVH"
     gene            13367..14026
                     /locus_tag="RPH49_001241"
     CDS             13367..14026
                     /locus_tag="RPH49_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124407.1"
                     /translation="MFGSDLDSAQLLQALYETLYMVSIALFLGAVIGIPLGVLLVITR
                     KQGIWPNIVIHQVLNPLINILRSLPFIILLIAIVPFTKLVVGTSIGTTAAIVPLTVYV
                     APYIARLVENSLLEVDEGIIEAAKAMGASPLQIIRYFLIPEALGSLVLAITTAIIGLI
                     GSTAMAGAVGGGGIGDLALVYGYQRFDTTVIIITVIVLVIIVQVIQTLGNVLARFIRR
                     H"
     gene            14063..14905
                     /gene="gmpC"
                     /locus_tag="RPH49_001242"
     CDS             14063..14905
                     /gene="gmpC"
                     /locus_tag="RPH49_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter
                     glycylmethionine-binding lipoprotein"
                     /protein_id="HDY5124408.1"
                     /translation="MKRLIGLVIVALVLLAACGSNNDKKVTIGVASNDTKAWEKVKEL
                     AKKDDIDVEIKHFSDYNLPNKALNDGDIDMNAFQHFAFLDQYKKAHKGTKISALSTTV
                     LAPLGIYSDKIKDVKKVKDGAKVVIPNDVSNQARALKLLEAAGLIKLKKDFGLAGTVK
                     DITSNPKHLKITAVDAQQTARALSDVDIAVINNGVATKAGKDPKNDPIFLEKSNSDAV
                     KPYINIVAVNDKDLDNKTYAKIVELYHSKEAQKALQEDVKDGEKPVNLSKDEIKAIET
                     SLAK"
     gene            15238..16245
                     /gene="aaa"
                     /locus_tag="RPH49_001243"
     CDS             15238..16245
                     /gene="aaa"
                     /locus_tag="RPH49_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin/adhesin Aaa"
                     /protein_id="HDY5124409.1"
                     /translation="MQKKVIAAIIGTSAISAVAATQANAATTHTVKPGESVWAISNKY
                     GISIAKLKSLNNLTSNLIFPNQVLKVSGSSNSTSNSSRPSTNSGGGSYYTVQAGDSLS
                     LIASKYGTTYQNIMRLNGLNNFFIYPGQKLKVSGTASSSNSASNSSRPSTNSSGGSYY
                     TVQAGDSLSLIASKYGTTYQKIMSLNGLNNFFIYPGQKLKVTGNATSSNSASATTTNR
                     GYNTPVFSHQNLYTWGQCTYHVFNRRAEIGKGISTYWWNANNWDNAAAADGYTIDNRP
                     TVGSIAQTDVGYYGHVMFVERVNNDGSILVSEMNYSAAPGILTYRTVPAYQVNNYRYI
                     H"
     gene            complement(16430..16699)
                     /locus_tag="RPH49_001244"
     CDS             complement(16430..16699)
                     /locus_tag="RPH49_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124410.1"
                     /translation="MAKRSKSQRLSSLLNVAGFIVDGYNGYKYHAKNKKLVYLSLGLS
                     TVGTVLDFYISIKSPRKFKKAVAVVTLITNGARLFTSIRKVKHEY"
     gene            16848..17243
                     /locus_tag="RPH49_001245"
     CDS             16848..17243
                     /locus_tag="RPH49_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDY5124411.1"
                     /translation="MIKCVCLVEETADKILLVQVRNREKYYFPGGKIEEGESQVQALL
                     REVKEELNLTLTMDEIEYIGTIVGPAYPQQDMLTELNGFRALTKIDWENVTINNEITD
                     IRWMDKDNDALIAPAVKVWIETYGGKHDK"
     gene            17233..17718
                     /locus_tag="RPH49_001246"
     CDS             17233..17718
                     /locus_tag="RPH49_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124412.1"
                     /translation="MTNNDTIMLRHYVPQDYSMLEAFQLSESDLKFVKTPEENITAAM
                     SDNERYPIVVMDGRQCVAFFTLHRGKGVAPFSDNQDAVFFRSFSVDQRYRNRGIGKVV
                     MEKLASFITSTFQGINEIVLTVNTDNPHAMALYRQQGYQYMGDSMFVGRPVHIMALTI
                     K"
     gene            complement(17887..18669)
                     /locus_tag="RPH49_001247"
     CDS             complement(17887..18669)
                     /locus_tag="RPH49_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDY5124413.1"
                     /translation="MNAVFILALLLLFLMIIFGGKKGFISYLTLFLNFAILIISIVLI
                     IFGVPIYVVTFFFCIIIGACNLFVLNSYNVKTQAAFISTIVTTILLITLIYLSVYFGH
                     LQGFSTEQQDETYVYSMNIGIDMVQFMVFTIILAVIAAVIDLTITISSPIYELHQVNP
                     TLTQYELFQSGMRVGREILATSANTIYLAFFGGQLALFIWFFKLKYSFGHIINSKIFA
                     QEFISIILGGIAVAISIPITAWITAFLIKRPSRQRKNDESIN"
     gene            complement(18666..19784)
                     /locus_tag="RPH49_001248"
     CDS             complement(18666..19784)
                     /locus_tag="RPH49_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDY5124414.1"
                     /translation="MFLKYRNLFTKPFNIILGLFCIAFIGAILFTFNNENFYNKPIGQ
                     IIDVKHVSSTPTKDAQNNRDIKYKNQLKVKILNGQFAGETTTINHQYVKSQADSEAFR
                     THEKVLLHISNKPSDAYIIEKKRDTLTVIITGLFLLTVLLVGRKVGLQSILSLILNSI
                     AILIAIYIHIQHSNINLFLLMTIAMICSTVLTLLLVTGWHMRTLITIASTIIGTFLSI
                     GLTELIIYMTDGKGIKYETMNFLSLPPKDIFLASVLIGSLGAIMDVAITIASGMHEIL
                     QRTPHISMRRWALAGRYIGQDIMGTMTNILLFSYLSGALPMFLIFLKNANTVTYTISM
                     NWSLEIARALTGGIGIVLTIPITILFMEIFETLRRAKQ"
     gene            complement(19899..20783)
                     /locus_tag="RPH49_001249"
     CDS             complement(19899..20783)
                     /locus_tag="RPH49_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5124415.1"
                     /translation="MEIKQLRYFIEVAKREHISETALELNIAQSAISRQITLLEQELN
                     VSLFKKQGRNITLTSEGKLLFNEALRIIEHLDSTIEQFQSHGLTKNKSIYIGYDESDV
                     SHMLLPLIQTFHLQNDTHVIPNLLEHDTIINSVLNGNIDIGFTELTPEIRKHKQLHML
                     PLFEEHYHLYAPSDDPITMATHPPLIQFEHSHIYCLAPFAETVKKQLRKITKSDVYTI
                     SSQPLAQYLLRQKEGYIISSQNIHLPESKSWIDIKLDHTELKRTICAITKEPYTKSDI
                     GILLTLIQQLMTKTSTFH"
     gene            20964..25463
                     /gene="gltB"
                     /locus_tag="RPH49_001250"
     CDS             20964..25463
                     /gene="gltB"
                     /locus_tag="RPH49_001250"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDY5124416.1"
                     /translation="MHNEKLIKGLYDYREEHDACGIGFYANMDNKRSHDIIDKSLEML
                     RRLDHRGGVGADGITGDGAGIMTEIPFAFFKQHVTDFDIPGEGEYAVGLFFSKERVLG
                     SEHEAVFKKYFEGEGLSILGYRNVPVNKDAIAKHVADTMPVIQQVFIDIRDIEDVEKH
                     LFLARKQLEFYSTQCDLELYFTSLSRKTIVYKGWLRSDQIKKLYTDLSDDLYQSKLGL
                     VHSRFSTNTFPSWKRAHPNRMLMHNGEINTIKGNVNWMRARQHKLIETLFGEDQHKVF
                     QIVDEDGSDSAIVDNALEFLSLAMEPEKAAMLLIPEPWLYNEANDANVRAFYEFYSYL
                     MEPWDGPTMISFCNGDKLGALTDRNGLRPGRYTITKDNFIVFSSEVGVVDVPENNVAF
                     KGQLNPGKLLLVDFKQNKVIENNDLKGAIAGELPYKAWIDNHKVDFDFENIQYQDSQW
                     KDETLFKLQRQFAYTKEEIHKYIQELVEGKKDPIGAMGYDAPIAVLNERPESLFNYFK
                     QLFAQVTNPPIDAYREKIVTSELSYLGGEGNLLAPDETVLDRIQLKRPVLNESHLAAI
                     DQEHFKLTYLSTVYEGDLEDALEALGREAVNAVKQGAQILVLDDSGLVDSNGFAMPML
                     LAISHVHQLLIKADLRMSTSLVAKSGETREVHHVACLLAYGANAIVPYLAQRTVEQLT
                     LTEGLQGTVVDNVKTYTDVLSEGVIKVMAKMGISTVQSYQGAQIFEAIGLSHDVIDRY
                     FTGTQSKLSGISIDQIDAENKARQQSDDNYLASGSTFQWRQQGQHHAFNPESIFLLQH
                     ACKENDYAQFKAYSEAVNKNRTDHIRHLLEFKACTPIDIDQVEPVSDIVKRFNTGAMS
                     YGSISAEAHETLAQAMNQLGGKSNSGEGGEDAKRYEVQVDGSNKVSAIKQVASGRFGV
                     TSDYLQHAKEIQIKVAQGAKPGEGGQLPGTKVYPWIAKTRGSTPGIGLISPPPHHDIY
                     SIEDLAQLIHDLKNANKDADIAVKLVSKTGVGTIASGVAKAFADKIVISGYDGGTGAS
                     PKTSIQHAGVPWEIGLAETHQTLKLNDLRSRVKLETDGKLLTGKDVAYACALGAEEFG
                     FATAPLVVLGCIMMRVCHKDTCPVGVATQNKDLRALYRGKAHHVVNFMHFIAQELREI
                     LASLGLKRVEDLVGRTDLLQRSSTLKANSKAASIDVEKLLCPFDGPNTKEIQQNHNLE
                     HGFDLTNLYEVTKPYITEGRRYTGSFTVNNEQRDVGVITGSEISKQYGEAGLPENTIN
                     VYTNGHAGQSLAAYAPKGLMIHHTGDANDYVGKGLSGGTVIVKAPFEERQNEIIAGNV
                     SFYGATGGKAFINGSAGERFCIRNSGVDVVVEGIGDHGLEYMTGGHVINLGDVGKNFG
                     QGMSGGIAYVIPSDVEAFVENNQLDTLSFTKIKHQEEKAFIKQMLEEHVSHTNSTRAI
                     HVLKHFDRIEDVVVKVIPKDYQLMMQKIHLHKSLHDNEDEAMLAAFYDDSKTIDAKHK
                     PAVVY"
     gene            25481..26944
                     /locus_tag="RPH49_001251"
     CDS             25481..26944
                     /locus_tag="RPH49_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit beta"
                     /protein_id="HDY5124417.1"
                     /translation="MGEFKGFMKYDKQYLGELSLVDRLKHHKAYQQRFTKEDASIQGA
                     RCMDCGTPFCQTGQQYGRETIGCPIGNYIPEWNDLVYHQDFKTAYERLSETNNFPDFT
                     GRVCPAPCESACVMKINRESIAIKGIERTIIDEAFENGWVAPKVPSRRRDEKVAIVGS
                     GPAGLTAAEELNLLGYQVTIYERARESGGLLMYGIPNMKLDKDVVRRRIKLMEEAGIT
                     FINGVEVGVDIDKATLESEYDAIILCTGAQKGRDLPLEGRMGDGIHFAMDYLTEQTQL
                     LNGEIDDITITAKDKNVIIIGAGDTGADCVATALRENCKSIVQFNKYTKLPEAITFTE
                     NASWPLAMPVFKMDYAHQEYEAKFGKEPRAYGVQTMRYDVDDKGHIRGLYTQILEQGE
                     NGMVMKEGPERFWPADLVLLSIGFEGTEPTVPNAFNIKTDRNRIVADDTNYQTNNEKV
                     FAAGDARRGQSLVVWAIKEGRGVAKAVDQYLASKVCV"
     gene            27213..27305
                     /locus_tag="RPH49_001252"
     tRNA            27213..27305
                     /locus_tag="RPH49_001252"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:27249..27251,aa:Ser,seq:tga)
     gene            27776..29203
                     /gene="treP"
                     /locus_tag="RPH49_001253"
     CDS             27776..29203
                     /gene="treP"
                     /locus_tag="RPH49_001253"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDY5124418.1"
                     /translation="MAVKREDVKAIVTAIGGKENLEAATHCVTRLRLVLKDESKVDKD
                     ALSNNALVKGQFKADHQYQIVIGPGTVDEVYKQFIDETGAQEASKDEAKKAAAQKGNP
                     VQRLIKLLGDIFIPILPAIVTAGLLMGINNLLTMKGLFGPKALIEMYPQIADISNIIN
                     VIASTAFIFLPALIGWSSMRVFGGSPILGIVLGLILMHPQLVSQYDLAKGNIPTWNLF
                     GLEIKQLNYQGQVLPVLIAAYVLAKIEKGLNKVVHDSIKMLVVGPVALLVTGFLAFII
                     IGPVALLIGTGITSGVTFIFQHAGWLGGAIYGLLYAPLVITGLHHMFLAVDFQLMGSS
                     LGGTYLWPIVAISNICQGSAAFGAWFVYKRRKMVKEEGLALTSCISGMLGVTEPAMFG
                     VNLPLKYPFIAAISTSCVLGAIVGMNNVLGKVGVGGVPAFISIQKEFWPVYLIVTAIA
                     IVVPCILTIVMSHFSKQKAKEIVED"
     gene            29267..30907
                     /gene="treC"
                     /locus_tag="RPH49_001254"
     CDS             29267..30907
                     /gene="treC"
                     /locus_tag="RPH49_001254"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDY5124419.1"
                     /translation="MSKEIDWRKSVVYQIYPKSFNDTTGNGIGDINGIIEKLDYIKLL
                     GVDYIWLTPVYESPMNDNGYDISNYLEINEDFGTMDDFEKLIKVAHQKDLKVMLDIVI
                     NHTSTEHEWFKEARKSKDNPYRDYYFFRSSEDGPPTNWHSKFGGNAWKYDSETDEYYL
                     HLFDVSQADLNWDNPEVRQSLYRIVNHWIDFGVDGFRFDVINLISKGEFKDSDKIGKE
                     FYTDGPRVHEFLHELNRQTFGNTDMMTVGEMSSTTIENCIKYTQPERQELNSVFNFHH
                     LKVDYVDGEKWTNAKLDFHKLKEILMQWQRGIYDGGGWNAIFWCNHDQPRVVSRFGDD
                     TSEEMRIQSAKMLAIALHMLQGTLYIYQGEEIGMTDPHFTSIAQYRDVESINAYHQLL
                     SEGHAEADVLAILGQKSRDNSRTPMQWSDDVNAGFTAGKPWIDISENYHQVNVRQALQ
                     NKDSIFYTYQKLIQLRHTHDIITYGDIVPRFMDHDHLFVYERHYKNQQWLVIANFSAS
                     AVDLPEGLAREGRVVIQTGTVENNTISGFGAIVIETNA"
     gene            30932..31660
                     /gene="treR"
                     /locus_tag="RPH49_001255"
     CDS             30932..31660
                     /gene="treR"
                     /locus_tag="RPH49_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDY5124420.1"
                     /translation="MAKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRE
                     TVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVV
                     NEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVA
                     SDSIYDYLEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMP
                     FQYNISKHLANEFKFNDFSRRRTK"
     gene            31722..31991
                     /gene="ffs"
                     /locus_tag="RPH49_001256"
     ncRNA           31722..31991
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RPH49_001256"
                     /product="signal recognition particle sRNA large type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01854"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01854"
     gene            32064..32165
                     /locus_tag="RPH49_001257"
     CDS             32064..32165
                     /locus_tag="RPH49_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124421.1"
                     /translation="MKTIQRIIRGTCLWEVAFLYVKFDSSELDVQFE"
     gene            32303..32827
                     /locus_tag="RPH49_001258"
     CDS             32303..32827
                     /locus_tag="RPH49_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDY5124422.1"
                     /translation="MQIYLSTLTELDYDKSLNSIEESFDDNPETSWQARAKVKHLRKS
                     PCYNFELEVIAKNENNDVVGHVLLIEVEINSDDKTYYGLAIASLSVHPELRGQKLGRG
                     LVQAVEERAKAQEYSTVVVDHCFDYFEKLGYQNAAEHDIKLESGDAPLLVKYLWDNLT
                     DAPHGIVKFPEHFY"
     gene            32896..34593
                     /gene="dnaX"
                     /locus_tag="RPH49_001259"
     CDS             32896..34593
                     /gene="dnaX"
                     /locus_tag="RPH49_001259"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDY5124423.1"
                     /translation="MNYQALYRMYRPQSFEDVVGQEHVTKTLRNAISKEKQSHAYIFS
                     GPRGTGKTSIAKVFAKAINCLNSTDGEPCNECHICKGITQGTNSDVIEIDAASNNGVD
                     EIRNIRDKVKYAPSESKYKVYIIDEVHMLTTGAFNALLKTLEEPPAHAIFILATTEPH
                     KIPPTIISRAQRFDFKAISLDQIVERLKFVADAQQIECEDAALAFIAKASEGGMRDAL
                     SIMDQAIAFGDGTLTLQDALNVTGSVHDEALDHLFDDIVQGDVQASFKKYHQFITEGK
                     EVNRLINDMIYFVRDTIMNKTSEKDTEYRALMNLELDMLYQMIDLINDTLVSIRFSVN
                     QNVHFEVLLVKLAEQIKGQPQVIANVAEPAQIASSPNTDVLLQRMEQLEQELKTLKAQ
                     GVSVAPTQKSSKKPVRGIQKSKNAFSMQQIAKVLDKANKADIKLLKDHWQEVIDHAKN
                     NDKKSLVSLLQNSEPVAASEDHVLVKFEEEIHCEIVNKDDEKRSSIESVVCNIVNKNV
                     KVVGVPSDQWQRVRTEYLQNRKNEGDDMPKQQAQQTDIAQKAKDLFGEETVHVIDEE"
     gene            34683..35000
                     /locus_tag="RPH49_001260"
     CDS             34683..35000
                     /locus_tag="RPH49_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002479279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDY5124424.1"
                     /translation="MRGGGNMQQMMKQMQKMQKKMAQEQEKLKEERIVGTAGGGMVAV
                     TVTGHKEVVDVEIKEEAVDPDDIEMLQDLVLAATNEAMNKADELTQERLGKHTQGLNI
                     PGM"
     gene            35007..35603
                     /gene="recR"
                     /locus_tag="RPH49_001261"
     CDS             35007..35603
                     /gene="recR"
                     /locus_tag="RPH49_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009383386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDY5124425.1"
                     /translation="MHYPEPISKLIDSFMKLPGIGPKTAQRLAFHTLDMKEDDVVQFA
                     KALVDVKRELTYCSVCGHITENDPCYICEDKQRDRSVICVVEDDKDVIAMEKMREYKG
                     LYHVLHGSISPMDGIGPEDINIPSLIERLKSDEVSELILAMNPNLEGESTAMYISRLV
                     KPIGIKVTRLAQGLSVGGDLEYADEVTLSKAIAGRTEM"
     gene            35808..35913
                     /locus_tag="RPH49_001262"
                     /pseudo
     CDS             35808..35913
                     /locus_tag="RPH49_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499028.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT        11997 a         5305 c         7559 g        11491 t
ORIGIN      
        1 atttcgcacg ccaaatcatg aatgtctcag acctcgagta tcaaacataa aacacgccac
       61 aaaaatataa cgcgtcagac tacaaagatc acgaatattc cgtacgtccc acgaagaaca
      121 tcctatacaa aaaaaccaag accatttatt tgcaacaaac taacaagact aacctcacat
      181 caataaatca acacaaagca aagccaccat ccctattggc atagtggcct gagaatttta
      241 agtattcaat tcgcttaaat tattttgcga aaatgtcgat aattgctttg atgattttaa
      301 tgatagtacc tacaatagcc atcgttttgt cctcctgtat gttgatttaa catagtgatg
      361 agttgttgat cgttaatgtt tgagattagt tgttacctaa aaatttacca agtaaatctt
      421 taaagaattt gaataatttt gctacgaatt ccatgtgaat ggcccccttc aaataagatg
      481 ttcatatcta tgagattttt ataacttact taccagtgaa tttctcaatt aatcctttaa
      541 tgaatttaat gattcctgca atgataccca tgtgaaagac ctcctttgtt tgttatgaaa
      601 tcttatttac cagtgaattg ttcgattaag cttttgataa ctttaatgat gccagcgatg
      661 atacccatta agattacctc ctttgcttat gagttaactt cattgtacat agttatcttg
      721 tgcgtaattg atttttttcc taacttgaat tgttatgatc ataactgcga attttttatt
      781 ttaaaaggac gggaaatact gcctaactgt acaggtgcat ttacaaaatc tttacaatca
      841 ttggtttaat agaggttaag ctgatgaatt tgacatgaag cagaaattta attatatttt
      901 atgttataag tttaaaacga ataacacgtt aggtctcgtc taggcaaagc atatttatga
      961 agatgaattg aacagacaga agtaacattt tatatacata tgtgcatggg agcacgctta
     1021 aagagaacac tgcaacaagg tatatcaacg taccgtgatg cagtgtctag ttaaactgaa
     1081 acctgcaata gtaaattttc tgccattatg tacagaatct actattgtag gtttttattt
     1141 ttatacataa gcaattatgc gagagattag aaataaggag gttatgcagt gttaagtttt
     1201 caattgctat tttcactgtt tgttattgcg cttatcattg cattgataag tggcttgttg
     1261 tttttagcac cagttatgcc aatgagatat attaaattac atttatacat actagtcatg
     1321 ccagtattat ttgcagtcat tggctttttc ggtattcatg gtcaacatgt cttaggtcca
     1381 tttaaaatag atcgtttatc ttggttatta gctggctttg taatggcgct tggctttatt
     1441 attcaaaagt tttcaatgcg atatttacta ggtgatcatc attatagaca ttactttcca
     1501 ttgttcactg cgattacgtc gtttgcatct ttagcatgga tgtctgaaga cttaagactg
     1561 atggcactct gctggggtat gacattatta tgtttaacat tgctgatgaa cgttaatcgt
     1621 ttttggaaag tgccacgtga gtctgcgaaa ttatcaagta tgacattttt atgtggttgg
     1681 cttgcattcg ttggagcaat tgtaactatt tatattgcga ctggcgagtg gcgcgtgcct
     1741 caacatatgt ctaattcgac atggtcattg ttgacgaatg tactacttgt attagctgtc
     1801 atgataccgg cagcacaatt tccttttcat cgatggttga ttgaatctgt aacggcacca
     1861 acgccagtat cggcaattat gcatgcagga attgtgaatg caggtggtgt tattctaact
     1921 cgttttgcgc cgatatttga taatggattt gcgttatcat tattacttat cctttctagt
     1981 atttctgtat tgttaggatc gggtattagc ttagttcaag ttgactataa acgccaatta
     2041 gtgggctcta cgatgagtca aatgggcttt atgttagttc aatgtgcatt gggtgtatat
     2101 tcagcagcga ttattcattt aatattgcac ggtattttta aagcaacatt atttttacaa
     2161 tcaggttcta tcgtgaagcg attcaatatt ccaaaacaag catctgctaa agacgcttat
     2221 ggctggattg tcatgggacg tgtattagct attatcgtgg catttctatt ttggatgagt
     2281 agtgacagaa gtgcatatga agtgttaagt gcactcattc tagcatggtc attacttgta
     2341 tcttggaatc agatggtagc ctttagtaaa gggcgcatgg cacgtcttgt tggcatgatt
     2401 ttgattgcaa ttgtgacatt tatctacatc atcacacata attattttta cgatgtattg
     2461 cgaaatataa caacacatgc gacaacaccg cctacagtga gtgtcatcat tagtgttgtc
     2521 attttaatct ttggtagttt attaagtatt tgggtggcgc gtcatcgata ctctaagggt
     2581 tttgcggtat tgtacgtgtg gttagttaat ctaggtgaag cacgctcgaa agcgatagaa
     2641 agtcatccga attatttgaa gaagtattta taggaggtga aaggtatgac aacacagtta
     2701 aatatcaatt cagtcattga aaatgcgaaa cgtgttatta caccattatc accaatttcg
     2761 atttttgcag cacgaaatcc atgggaagga ttagaagcgg atacgtttga agatgttgca
     2821 aaatggttac gtgatgttcg agatgtggat atttttccaa ataaagcatt aatagaaagt
     2881 gctgtggcac gtggtgaatt agacgaaagt gtctttaatc aacttgttac tgatatgtta
     2941 cttgaacatc actacaatat cccgcaacac tacatcaatc tttatattga taacattaaa
     3001 acattaaaag acgtacctac atcatatatg aatcattcaa atgttgatgt tgttgctgat
     3061 ctactattag aaaaatcaaa acgtgatatg gctgaatcat atcatcacta tgatgtacgt
     3121 ccgatgagtg atgcaataat agatgaacaa ggtgagccac ttagcgaaca agtgaatcgt
     3181 caaatgatta aatggacgaa aatttatatc gatcaatttc tatcgagttg gacaatgccg
     3241 aagcgagagc aaagttttta ccatgcatgg ttgcatttag cgcaacatga ccatagtttt
     3301 actaaagcac agcgccaagt gattaaaggc ttacccaatg atcctgaaat gacgatagag
     3361 tcagtattaa ctcatttttc aatagcgcag gaagactacc aagcttgtgt tgaaggacat
     3421 cttttggcgt taccgggttg ggcaggtatg ttgtattacc gttcacaaca gcatcacttt
     3481 gaacaacatt tgttaacgga ttatttggcc attcggttag ttgtcgaaca attgctagtt
     3541 ggtgatgagt ttaagtcagt cactaaagat tgtgaaagta gatcggaaaa ttggtttaag
     3601 caaactgttg catcatggtg ttactacagt gatatgccta gcgatgtatt actacaacat
     3661 gacgtcaatg aaattcaaac gtttattcat tttgcagcaa ctatgaataa aaatgtattt
     3721 aaaaatttat ggctaattgc ctgggaaatg acatacgaat ctcagttaaa acaaaaaatt
     3781 aaagcaggtc atgagagtgt ggcgggcgca ttagatgtaa accaagtaaa tgtctcagaa
     3841 aatgataacg ctaatcagcc acattcagta ttgttaaatg acacacaagc agttgatgaa
     3901 aataatagcg agctaaatca gatgggcaca tcaacgaaag cgcaaattgc attttgtata
     3961 gatgttcgtt cagaaccatt tcgtagacat atcgaagcgg cagggccctt tgaaacgatt
     4021 ggtattgcag gtttctttgg attacctatt caaaaagatg ccgtagacga acaattcaaa
     4081 catgattcat tacctgtcat ggtaccgccg gcatatcgca ttaaagaatt tgcagaccgc
     4141 tacgatatga atgtttatcg acaacagcaa cagacaatgt catcgatgtt ttacacattt
     4201 aaattgatga aaaataatgt catgcctagt ctgttattgc ctgaattaag tgggccattt
     4261 ttaagcttga gtaccattgt caattcgatt atgcctagaa aaagtcgcgc gtctttacaa
     4321 aaaataaaac aaaaatggtt gaaaaagcct gaaacaaagt taacgattga tcgtgagttt
     4381 gaccgaacat cagacttacc tgttggattt actgagcaag agcaaattga tttcgcgtta
     4441 caagcgttga aattgatgga tttaaccgaa gcatttgcgc cgttcgttgt gttagcaggt
     4501 catgctagtc attctcataa taatccacat catgcatcac ttgaatgtgg ggcttgtggt
     4561 ggcgcatcaa gcggttttaa tgctaagtta ttagcgatga tatgtaatcg tccaaatgtc
     4621 agacaaggat taaaacaagc aggcgtagta attccggaga caactgtttt tgcggcagca
     4681 gaacatcata cgtctactga tacgttggca tgggtatatg tgccagacac attatcagct
     4741 ttagctctag atgcatatga atcattgaat gacgcgatgc cgatgatttc tgaacacgcg
     4801 aatcgcgaac gtttggacaa actgccaacg attggtcgtg tgaatcatcc agtggaagaa
     4861 gcgcagcggt ttgcgagtga ttggagtgag gtacgtccag aatggggctt ggctaaaaat
     4921 gcatcattta taattggacg acgccaatta acaaaaggca ttgatttaga agggcggaca
     4981 tttttacaca attatgattg gcgtaaagat aaagatggca cattgttaaa taccatcatt
     5041 tctggtccgg cacttgtggc acaatggatt aatttacaat attatgcgtc gacagttgcg
     5101 ccgcattttt acggaagtgg gaataaagcg acacaaaccg tcacgtcagg tgttggtgtc
     5161 atgcaaggta atgcgagtga tctgatgtat ggcttatcat ggcaatctgt tatggctgct
     5221 gatcgaacga tgtatcattc gccaattcgt ttgcttgtcg ttgttcaggc acccgactat
     5281 gttgtagcaa gactactcgc gaataatgac catttcgcta ggaaggtgtc taatcattgg
     5341 ctgcgtttaa tgagcgttaa tgaggaaggg cgttttaaaa gttggattta acgatgatat
     5401 gttgcgatgc taagtaacta atatatcatc atatctacaa tgttctagct tcttaaaata
     5461 tactaaaaat gataaactta atgtaatagt tgatgtcgtg ataacgatac aaagatgaag
     5521 taatcaattt taatattatt ggagttagtg atatgaaaag aacgaaaggt gaaatcgaag
     5581 ctgaaatcag taaagccatt acgcaatggg aaaaagattt ccttggcaga ggttccttgt
     5641 cagttaaatc agacatttta agagatatgg tgattattag tttacaaggt atcttaacgc
     5701 cagcagaata tcgtgtgtgt agtacgaatg aaggattatt aaatattaaa cgaacacgtt
     5761 ctgaattagt tgaatccggt gagcaagatt tgaatgatat cattcttaaa attacaggta
     5821 tcaaagtgat gagcttccac agtgatttaa gtacagttac aggtgaacgt attatcgtat
     5881 tcaaacttga ggataatttg gaaaagcata tttaagaagg ttaggtatgc ttctgctggc
     5941 ttattaaagc tatagaagta tgcttggtta aacagcgcaa cgccatatat ttgggtgtgc
     6001 tgtttttcta ttatatgatg tgtttattac gtggatgaat gcgtgggtct gaatatagcc
     6061 cgtgaaaggc gtatgtcata aaatttgcga atggtgacaa gtcaacgcaa gcatatttgt
     6121 tgcgagacat gcccactatc cttttacata aagagtatat gtgtgacgta tgcatataat
     6181 cgataaagta tacctaaaaa attaggtata atgaccattg ttgcaataag tttttcggcc
     6241 ttgaaaccga taacgcatag tataatagga ataaaatata atacaaatat ccagtaaatc
     6301 aaatttgaaa acgatggatg aataggggta aagaatctaa ctaatgtaat gattaacgct
     6361 atatagacaa aaataactct attgatacgc cttaccccct ctgtataata actataaatc
     6421 gtactaaatt gaaaatagca aaatattgtt atttcaatta tacaatgttt tatttgcaat
     6481 atacataaca atatgaactt tataattttg atattgtcgg taaagtgaaa tttgtggcac
     6541 attgatatta tggataacat ttgtaaaatg aaaatgatga tacgaggaga ttgtaagatg
     6601 atagataaaa aattaacatc accgaaaatg acagtgcctt tatttttaat cgcgctgatt
     6661 gtatttatag gtatgtttta cagtgtagtg acaaatcaag aatggcttaa aaatatagat
     6721 atgggatcat taacatggtt tacagattat ttcggtgagc cacaacgtca gtatgttaac
     6781 aatttattta attactatat gacgtttagt gcggaaattg gagatgtcaa aggtgtcgtg
     6841 ttgatttcca ttatcatcac aatcatactg tttattaaac agaggcattt agcggtttgg
     6901 tttgtgacat atttggtttc aggcgtcatc atgaacaaat taattaaaga tactgtttta
     6961 cgtccaagac catataatca tttagccgtt gatacaggct tttcatttcc aagtggacat
     7021 tccaacgcca gcacattatt atatttcgcc ttaatgatca taattatttc acttgctgct
     7081 aagacaataa caaaagtgtt gagtgcgcta gttatgggaa tattatggct tagcatatta
     7141 ttttgtcgcc tttattttca tgcgcattac ttttcagatg tcattggcgg cacgtcacta
     7201 gcaatcattt gggtagcgtt attcttaatg gtatacccat actttattaa tcatcgacga
     7261 caacgcgttt agcaaacatc tttagacata gtggaggtat atagaaaaat gagaattaaa
     7321 acaccgagtc catcgtattt aaaaggcaca aatggacatg cgatattatt attacattca
     7381 tttacaggta caaatcggga tgtgaagcat cttgcagctg agttaaatgc acaaggattt
     7441 agttgttatg caccgaatta tccaggtcat ggcttactgt tgaaagattt catgacatat
     7501 aatgtagatg attggtggga agaagttgag aaagcttacc aatttttagt caatgaaggt
     7561 tatgaatcta tcagtgcaac gggtgtgtct ttaggtggat taatgacatt aaaattggcg
     7621 caacactatc ctttgaaacg tatcgctgtc atgtcagcac caaaggaaaa gagtgacgat
     7681 ggcttaatag aacatttagt ttattatagt caacgcatgt cgaatatttt aaatttagat
     7741 cagcaagcat cgagtgcgca attagcagca attgatgatt atgaaggtga aattacgaag
     7801 tttcaacatt ttattgatga tatcatgaca aatttaaatg ttattaaaat gccagctaat
     7861 atattatttg gtggtaaaga tgcgccatcc tatgaaacaa gtgcacattt tatttatgaa
     7921 catttaggat cagtagacaa agaattaaat ggtctgaagg attcgcatca tttaatgacg
     7981 catggagaag gcagagatat tttagaagaa aatgttattc gctttttcaa tgctttaaca
     8041 taattgaaga ttttaaaaat taacacttga gtgacgatgt tattatattt gtcatttgag
     8101 tgttttttgt ggcgtgatag tatagggaac ttagctaaag ttaatttgta gtgtgatgtc
     8161 gtggaaattt tatgggcatt gtacctgaag ttgttatgtg gcgagatgtt ggggatatag
     8221 atggtgttgt atgtggcgag atattggcgt acgtatacag cgttgaacca gaaaatttaa
     8281 tgtagcgtaa tgacaacaca ttacaagagt tgattatatt atgataaatc caggtgctac
     8341 cgtactaatg aaacaaattt gatgcaggtg tattgcatgt tatttacata catgttagag
     8401 tgttacttaa acacgtagac gctttaacgc tttaaaggag atgcgaatga tgaaaagaca
     8461 acaatcacaa tggaagtcat caactggatt tattttagct agtgcgggtt ctgcaatcgg
     8521 tcttggtgcc atgtggaaat tcccatatat ggcagggatt tatggcggcg gtgcctttct
     8581 agctatgttc ttaatattca ccatttttgt tgggttgcca ttactcatta tggaattcac
     8641 tgttgggaaa atgggacgga catatacaac acaaatatat agtaaattaa ctggtaaaaa
     8701 atggctcaat atcattggct ggaacggtaa tttggcagtg tttattttat ttggcttcta
     8761 tagtgttatc ggtggttgga ttgtcattta catcggacaa gtattatggc aattagttat
     8821 atttcaacgc atcaatcatc tccaagaaat gaattttgaa gcggtaatat caaatccttg
     8881 gttaactgtt ctagggcaag gtatattcat attcgctacg atgattattg tcatgttagg
     8941 tgttgaaaaa ggattagaaa aggcatcgaa agttatgatg ccattgctgt ttgtcttttt
     9001 aatcatcatt gtgattaagt ctttaacatt agatggtgcc ttagaaggtg tgaaatttat
     9061 tttacaacca agagtatcag agattactgc tgacggtatc ttgtttgcgc taggccaatc
     9121 attctttacg ttatcattag gaactacagg tatgattact tatgcgagtt atgcctctaa
     9181 agacatgacg attaagtcat cagctatttc tatcgttgtt atgaatatct ttgtatctgt
     9241 attggcaggt ctagctatat ttccggcgtt acatagtttt ggctatgaac cacaagaagg
     9301 gcctggatta ttatttaaag tactgccaat ggtctttagt caaatgcatc taggcacatt
     9361 attctatttg ggattcttag tgctgttctt atttgcggct ttaacgtcat ctatttcttt
     9421 attagaatta aatgtttcta acttcacgaa gaatgacaat acaaaacgta aaaaagtcgc
     9481 agtgatcggt agtattttag tatttatcat tagtattcca gcaaccttat cttttggtat
     9541 cttaaaagat gtaagattcg gtgcgggaac gatttttgat aatatggatt tcatcgtttc
     9601 gaatgtattg atgccattag gcgcattagg tactacgctt gtcgtaggac aattattaga
     9661 taaaaaatta ttacaacaat attttggtaa agatcgattt agattattca gtggttggta
     9721 ttacttaatt aagtatgcga tgcctgtcgt tattatctta gtctttatcg tgcaattatt
     9781 tagttaatat atagaagcat ctgacacaca agtatttgtg ttgatcaggt gtttttttgt
     9841 ttggaattga aaagttagta ctggttctga attaatcgaa acttagataa ttgcaaaata
     9901 acaaaatgtc gtttataatt cttatctgaa aagtaagaat taaaattgag atatgaagaa
     9961 aggtttcatt catttgatcg gcatgtcaga tgagggtgca tctatgatta cttatgattt
    10021 aattggcaat acaccattag ttctgttaga acattatagt gatgataaag ttaaaattta
    10081 tgccaagctt gaacaatgga atcctggagg cagtgttaaa gacagactcg ggaaatattt
    10141 agtagagaag gcaattcaag aagggcgtgt gcgtgcaggt caaactattg ttgaagcgac
    10201 tgctggtaat acaggcatag ggttagctat tgcagcgaat agacatcatt tgaaatgtaa
    10261 gatctttgcg ccgtatggtt tttcagaaga aaagattaat attatgatag cgcttggtgc
    10321 agatgtttca aggacgagtc agtctgaagg tatgcatggg gcacaattag ctgcacgttc
    10381 ctatgctgaa aaatatggtg ccgtttatat gaatcaattt gaatccgaac ataatccgga
    10441 tacatatttt catacattgg gacccgaatt gacttcagca ttacagcaaa ttgattattt
    10501 tgtggctggt attggctctg gcggtacatt tacaggtacc gcacgttatt taaagcaaca
    10561 tcacgtgcaa tgttatgccg ttgagccaga agggtccgtg ttaaatggag ggccagctca
    10621 tgcacatgac actgaaggta tcggttctga gaaatggccg atatttttag agagacgtct
    10681 tgtagatggg atatttacga ttaaagatca agatgccttt cgaaatgtca aaagtttggc
    10741 tataaatgaa gggttgttag taggcagttc ttcaggtgca gcattacaag gtgcattgaa
    10801 tttaaaagcg caattatctg aaggtacgat tgttgtcgta tttccagatg gtagcgatcg
    10861 atatatgtct aagcaaatat ttaattatga ggagaatgat tatgaataag aaaactaaat
    10921 taattcacgg tggacacaca acggacgact atacaggtgc agttactaca ccaatttatc
    10981 aaacaagtac atatttacaa gatgatattg gtgatttacg tcaaggatat gaatattctc
    11041 gtactgcgaa tccgacaaga agttctgtag aaagcgttat tgcggcatta gaaaatggca
    11101 aacatggctt tgcatttagt tcaggtgttg cagcaatcag tgcagttgtt atgctgttgg
    11161 acaaaggtga tcatattatt ttaaattcag atgtatacgg cggtacttat cgcgcattga
    11221 caaaagtatt tacacgattt ggcattgaag tggattttgt agatacaacg catacagatt
    11281 caattgtaca agcgatacgc ccaacaacaa agatgttgtt tattgaaaca ccttctaatc
    11341 cattattacg tgttactgac attaaaaagt ctgctgaaat tgcgaaagaa cacggtttga
    11401 tttcagtcgt tgataacaca tttatgacac cttattatca gaatccatta gatttaggta
    11461 tcgatattgt tttacattct gcaacgaaat atttaggtgg acatagtgat gtcgttgctg
    11521 gtttagttgc aacatcggat gacaagcttg cagaacgttt agcatttatt tcaaattcaa
    11581 caggtggcat tttaggacct caagatagct atttacttgt gaggggtatt aaaacattag
    11641 gtttacgtat ggaacaaatt aatcgcagtg ttattgaaat tattaaaatg ttacaagcac
    11701 atccagctgt gcaacaagtg ttccatccaa gtattgaaag tcatttaaat catgatgtcc
    11761 atatggctca agctgatggc catacaggtg tgattgcatt tgaagtgaaa gatacagaaa
    11821 gtgccaaaca attgattaaa gcaacatcgt attacacatt agctgaaagt ttaggtgcag
    11881 tggaaagttt aatttcagta cctgcactga tgacacatgc atccattcca gcagatattc
    11941 gagctaaaga aggtattaca gacggacttg taagaatttc tgtaggtatt gaagatactg
    12001 aagatttagt ggatgattta aaacaagcac tagatacgtt ataaataata gcagcactgg
    12061 catatatttt gagttcaacg tttgttgttc ttgaatatgc tagtgctttt ttgtgcgatg
    12121 ttaatatttc gtaattgcgt tgtggaggat tgctggtcat ttttattcat ttaattcgat
    12181 aaatgtcata gtagcctcac aattcatcat tgtcacatga attgcttatt ttttaatttt
    12241 ttagaaaatt cggcaaattg tattgacgat atatgcaatt ttacatataa tgctcttatt
    12301 cctagtggat taataagaat ttgtaggagg ggcgatgatg attgagtttc gacaggtaag
    12361 taagaccttt aataaaaaga agcaaaaaat acatgcttta aaagatgtat catttaaggt
    12421 caatcgcaat gatatttttg gtgtgattgg atacagtggt gctggaaaaa gtacgttggt
    12481 aagactcgtg aatcatcttg aagctgcctc aagtggtcaa gtgcttgtag atggacatga
    12541 tattacgaat tatagtgaaa aaggcatgcg agaaataaaa aaagatatcg gtatgatatt
    12601 tcagcatttc aatttattaa attcagctac cgtatttaaa aatgtagcaa tgccactcat
    12661 tttaagtaag aaaagcaaaa cagaaattaa gcaacgagta acggaaatgc ttgaatttgt
    12721 aggattgagt gataaaaaag accaatttcc tgatgaatta tctggtgggc agaagcaaag
    12781 ggtggctatt gcaagagcgc ttgttactaa tccgaaaata ctcctatgcg atgaagcaac
    12841 aagcgcattg gatccagcaa cgactgcttc gatattgacg ttattaaaga atgtcaatca
    12901 aacctttggc attacaatta tgatgattac acatgaaatg cgcgttatta aagacatttg
    12961 taatcgtgtt gctgtaatgg aaaaggggca agtggttgaa acaggaactg ttaaagaggt
    13021 gtttagtcat cctaaaacga cgattgctca aaattttgtg tctacagtta tacagactga
    13081 gccaagtaca tcattgattc gtcgattgaa tgacgaacaa gttggcgatt ttaaagatta
    13141 taaaatcttc gtcgaggaaa ctcaggtgac acaaccgatt ataaatgact tgattcaaat
    13201 ttgtggcaga gaggttaaaa ttttattttc atctatgtca gaaatacaag gtaacaccgt
    13261 atgttatatg tggcttcgat ttaatatgga tcaacaattt gatgacacgg caataaatca
    13321 atatttcaaa gagaaaaata ttcaatttga ggaggtgcat taacatatgt ttggttctga
    13381 tttagacagt gcacagttat tacaagcatt gtacgaaacg ctatatatgg tatctattgc
    13441 tttattttta ggagcagtga ttggtattcc attaggtgtc ttattggtaa ttactcgaaa
    13501 acaaggcata tggcccaata tagtgataca tcaagtttta aatcctttaa tcaatatttt
    13561 aaggtcacta ccatttatta ttttgttaat tgcgattgtg ccattcacaa aattagtagt
    13621 aggtacttca attggtacga ctgctgccat cgtgccttta acagtatatg tggcacctta
    13681 cattgcaaga cttgttgaaa actcattatt ggaagtagac gaggggatta ttgaagcggc
    13741 gaaagcgatg ggcgcttcac cactacaaat cattagatat tttttaatcc ctgaagcgtt
    13801 aggttcatta gtattagcaa ttaccactgc gattattgga cttattggaa gtacggcgat
    13861 ggcaggagct gttggcggtg gtggtatagg agacttagct ttagtgtatg gttatcaaag
    13921 atttgatacg acggtcatta ttattaccgt tattgtatta gtcattattg tccaagtgat
    13981 tcaaacgcta gggaatgttc tagctagatt catacgtaga cattaatggt atatagtgaa
    14041 gattttgaaa ggaattgata gaatgaaaag attgattggg ttagttatcg tagcacttgt
    14101 attattagca gcgtgtggta gtaacaatga taaaaaagta acaattggtg tcgcatcaaa
    14161 tgatactaag gcttgggaga aggttaaaga attagctaaa aaagatgata ttgatgtgga
    14221 gattaagcac ttttccgatt acaatttacc gaataaagca ttaaacgatg gtgatattga
    14281 tatgaatgca ttccaacatt ttgcattttt agatcagtat aagaaggcac ataaaggaac
    14341 aaagatttca gcattaagta caacagtttt agcaccgttg ggcatttact cagataaaat
    14401 taaagatgtc aaaaaggtta aagatggtgc taaagttgtc attccaaatg atgtatcaaa
    14461 ccaagcacgt gcacttaaac tattagaagc agctggttta ataaaactga aaaaagattt
    14521 cggtttggca ggcacggtga aagatataac gtcaaatcca aaacatttaa aaattactgc
    14581 agtagatgca caacaaactg cgcgtgcttt atctgatgtc gatattgcag ttattaataa
    14641 tggtgtagca actaaagcgg gtaaagatcc taaaaatgat ccgatatttt tagaaaaatc
    14701 aaattcagat gctgtaaagc catatattaa tattgttgca gttaatgaca aagacttgga
    14761 taacaaaaca tatgctaaaa tcgtagaatt gtatcattca aaagaagctc aaaaagcgtt
    14821 gcaggaagat gtcaaagatg gagagaaacc tgttaattta tctaaagatg agattaaggc
    14881 aatagaaacg tcattagcaa aataaataat attgcgtcct acaagcaaag ttcatgctta
    14941 tgtttgtagg gcgttattgt ttgacaataa aattatttcc aatagagaaa gggattgtaa
    15001 tcattttata gtgaaatatt atgaaattgt aataatttag atattgtaaa atctaataag
    15061 ttgtaataat tttaaggggt aattataaaa tttgatgata cagtatatga tttttttgta
    15121 atcataatgt catcaaacat caacctatta tacataatta aatcgtataa tgatgtagta
    15181 ttcataaatt cggataaaaa gaatgttagg aaagttaagc aagaggagga ttttaaagtg
    15241 caaaaaaaag taattgcagc tattattggg acaagcgcga ttagcgctgt tgcggcaact
    15301 caagcaaatg cggctacaac tcacacagta aaaccgggtg aatcagtgtg ggcaatttca
    15361 aataagtatg ggatttcgat tgctaaatta aagtcattaa acaatttaac atctaatcta
    15421 attttcccaa accaagtact aaaagtatct ggctcaagta attctacgag caatagtagc
    15481 cgtccatcaa caaattcagg tggcggatca tactatacag tacaagcagg tgactcattg
    15541 tcattaatcg catctaaata tggtacaact taccaaaaca ttatgcgact taatggttta
    15601 aataatttct ttatttatcc aggtcaaaaa ttaaaagtat caggtactgc aagctcaagt
    15661 aattctgcga gcaatagtag ccgtccatca acgaattcaa gcggtggatc atactacaca
    15721 gtacaagcag gtgactcatt gtcattaatc gcttcaaaat atggtacaac ttaccaaaaa
    15781 attatgagct taaatggctt aaataatttc tttatatatc cgggtcaaaa attaaaagta
    15841 actggtaatg caacatcttc aaactcagca tctgcaacaa ctacgaatag aggttacaat
    15901 acaccagtat tcagtcatca aaacttatat acatggggtc aatgtacata tcatgtattt
    15961 aatcgtcgtg ctgaaattgg taaaggtatt agtacttatt ggtggaatgc taataactgg
    16021 gataacgcag cggcagcaga tggttacact atcgacaata gacctactgt aggttctatc
    16081 gctcaaacag atgtaggtta ctatggtcat gttatgtttg tagaacgtgt aaataacgat
    16141 ggtagtattt tagtttcaga aatgaactat tcagctgcac caggtatttt aacttacaga
    16201 acggtaccag cttaccaagt aaataattat agatatattc actaaagtct tacgtatata
    16261 aatatataat gaattcctat tacatttcac aagctgaaaa gttggattga atcctaaact
    16321 ttatggcggg gctatcaaag tcgtgattgt tgtaatagga atttttgtat atgaaaaagg
    16381 attggtcgaa tgaacttcat gttctatgtt cgaccaatcc ttttctgaat tagtattcat
    16441 gctttacttt gcgaatgctt gtaaataatc tagcaccgtt tgttattaaa gtaacaactg
    16501 ccactgcttt tttgaactta cgtggtgact taattgaaat gtaaaagtct aacacggttc
    16561 ctacagtgct taaacctaat gaaagatata ctaatttttt atttttagca tgatatttat
    16621 agccattgta gccgtcgact atgaaacctg cgacatttag taaacttgat aaacgttgtg
    16681 atttggaacg ttttgccata atattaattc cccctagtat cttctgttta tatgaaaagt
    16741 tgggtgcgct gaattgctaa cgttttgcgc tataactact catatatgat aacataattg
    16801 tacagtataa tttgaaaaat tgatttcaca aagttggggt gtcaaagatg attaaatgtg
    16861 tctgtttagt tgaagaaaca gctgataaaa tattgcttgt tcaagtaagg aatcgcgaaa
    16921 agtattattt cccaggtggt aaaatagaag aaggggaatc acaagtacaa gcgctgttaa
    16981 gagaagtaaa agaagaatta aatttaacat taacaatgga tgaaattgaa tatatcggga
    17041 caattgtagg tcctgcatat ccacaacagg atatgttaac tgagttaaat ggatttcgcg
    17101 cattaaccaa aatcgattgg gaaaacgtaa ctatcaataa tgaaattacg gatatacgct
    17161 ggatggataa agataatgat gcgttgattg cgcctgctgt caaagtttgg attgaaacgt
    17221 atggtggtaa acatgacaaa taatgacacc atcatgttac gacattatgt cccacaagat
    17281 tattcgatgt tagaagcttt tcaattaagt gaaagtgatt tgaagtttgt taaaacgcca
    17341 gaggaaaata ttacagctgc aatgtctgat aatgaaaggt atcccatcgt tgtaatggat
    17401 ggcaggcaat gtgtggcctt ttttacatta catcgtggaa aaggggtcgc accatttagc
    17461 gataaccaag atgcagtatt tttcaggtca tttagtgttg atcaacgtta tcgtaataga
    17521 ggaataggta aagtggtaat ggaaaaattg gcgtcattta tcacttcaac atttcagggt
    17581 attaatgaga ttgtgttaac ggttaatact gacaatccac atgccatggc actttatcgc
    17641 caacaaggat atcaatatat gggagatagt atgttcgtcg gaagacctgt tcatattatg
    17701 gcgttaacta taaaataaat taaatttaaa agcatcttta ctcatcgtcg atcacaacaa
    17761 ttaatgatga ataaaggtgc tttttgttat agatcaccgg acaatttact atagtaaaaa
    17821 gcgacctagt gaacaattga catatatcca caggtcgctt aacttaaatt atattgctag
    17881 ttgcgattaa ttgatagact catcattttt gcgctgtcga gatggtcttt ttattaaaaa
    17941 tgccgtaatc caagccgtaa tcggaatact gattgcaacg gcaataccgc ctaaaataat
    18001 agaaataaat tcttgagcaa atattttcga gtttataata tgaccaaatg aatatttaag
    18061 tttgaaaaac caaataaata aagcaagttg gccaccaaaa aaggcaaggt aaatcgtgtt
    18121 cgcagatgtc gctaaaattt ctctaccaac acgcatgcca gattggaata attcgtattg
    18181 cgtaagtgtt ggattcactt gatgcaattc ataaatgggt gaactaatgg taatcgttaa
    18241 atctatcaca gctgcaataa cagcaagaat aatagtgaac accataaatt gaaccatatc
    18301 aatgccaata ttcattgaat acacatatgt ttcatcttgt tgttcggttg aaaagccttg
    18361 tagatgaccg aagtagaccg ataaataaat gagtgtaatc aacaatattg ttgtaacgat
    18421 agtgctgata aatgcagctt gtgttttaac attgtaacta ttgagtacga ataaattaca
    18481 agcgccaata ataatgcaga aaaagaatgt gacgacataa atcggtacgc caaaaataat
    18541 caacacaata ctaataatta aaatagcgaa atttaaaaat agggttaaat aagagatgaa
    18601 tcccttttta cctccgaaaa ttatcatcag aaagaggagc aataacgcca atataaatac
    18661 agcattcatt gtttcgccct ccttaatgtt tcaaatattt ccataaacaa tattgtgata
    18721 ggaattgtaa gtacgatacc tataccgcct gttagtgcgc gcgcaatttc taacgaccaa
    18781 ttcatcgaaa tagtataagt cacagtattt gcatttttta aaaagattaa aaacataggt
    18841 agtgcaccag ataaatatga gaataataag atgttagtca ttgttcccat aatatcttgg
    18901 ccgatgtatc gcccagcaag cgcccatctc ctcattgaaa tgtgtggcgt acgctgtaaa
    18961 atttcatgca taccactagc aattgtaatt gcaacatcca taatagcgcc aagtgaacct
    19021 attaacactg aggctaggaa gatatctttc ggtggtaatg ataaaaagtt catcgtttca
    19081 tatttaatgc ctttaccatc tgtcatatat atgattaatt ctgttaaacc tatactcaaa
    19141 aaagttccga taattgtact ggctatggta atgagtgtac gcatatgcca gcctgtaacg
    19201 agcaataaag tgagtactgt tgaacagatc atggcaatgg tcatgagtaa gaataaatta
    19261 atattgctat gttgaatatg aatgtaaatt gcgattaata tggcaataga attcaagatt
    19321 aacgataaaa tcgattgcag tccgactttg cgaccaacca ataatacagt taataagaac
    19381 aaaccagtga tgataaccgt taaggtatca cgcttctttt ctataatata agcatcactc
    19441 ggcttgttag aaatatgtaa taatactttt tcgtgtgtgc gaaatgcctc agaatctgct
    19501 tgtgatttga cgtactgatg attaatcgtc gttgtttctc cagcaaattg accatttaat
    19561 attttgactt ttaattgatt tttatattta atatcacgat tattttgtgc atcttttgta
    19621 ggtgtcgaag aaacatgttt gacatctata atttgaccaa ttggtttgtt gtaaaagttc
    19681 tcattattga atgtaaataa aatagcacca atgaatgcga tgcagaacaa acctaaaatt
    19741 atattaaatg gctttgtaaa taaatttcta tatttcaaaa acaaaacccc aattctatga
    19801 atgaattaat atggtgatta tacgccctta attttttatt ttcaaagata ttactgctaa
    19861 gtgtaaaacg aaaatcatca ttgatagcat cgaattactt aatggaatgt agacgtttta
    19921 gtcattaatt gctgaataag tgttaataat atgccaatat cactctttgt ataaggctcc
    19981 tttgtaatag cacatatcgt tctttttaat tcagtatgat ctaattttat atctatccat
    20041 gatttagatt ctggtaaatg tatattttgt gatgaaatga tgtaaccttc tttttgacga
    20101 aggagatact gcgcaagtgg ttggctactg attgtgtata catctgattt agtaatcttg
    20161 cgcaattgtt tttttacagt ttcggcaaat ggtgccaagc aataaatatg actatgctca
    20221 aactgaatta atggtgggtg tgtcgccatc gtaattggat cgtctgaagg cgcatataaa
    20281 tgatagtgct cttcgaataa aggtagcata tgtaattgtt tgtgtttacg tatttctggt
    20341 gtaagttccg tgaaaccaat gtctatattc ccatttaata cgctatttat aattgtgtca
    20401 tgttctaata aattagggat gacatgtgta tcattttgta aatgaaacgt ttggataagt
    20461 ggtagtaaca tgtgggatac gtcactctca tcatagccaa tgtagatact tttattttta
    20521 gttaatccat ggctttgaaa ttgttcaatc gtgctatcta aatgttcaat aatacgcaga
    20581 gcttcattaa ataataattt tccttcagat gtgagcgtaa tattgcgtcc ttgcttttta
    20641 aataaagaca cattaagttc ttgttctaat aatgtaattt gacggcttat cgctgattga
    20701 gcaatgttta gttcaagtgc tgtttcggag atatgttctc ttttagcgac ctcgataaaa
    20761 tatcttaatt gtttaatttc catagcgata taggcacctc caaaaatgag tgttttgtaa
    20821 ctattatagc aatattattg ataaatgttc tattttttag atgaatatct tctattttat
    20881 atattgaaca gataaatttt ttagattata gtaattatca ttaataacta atatcagaat
    20941 attctaaaaa aggggtgtgc atcatgcaca atgagaaatt aattaaaggc ttatatgact
    21001 atcgtgagga acatgatgcg tgtggtattg gtttttatgc gaatatggat aataaaaggt
    21061 ctcacgacat cattgataaa tcgcttgaaa tgttgcgacg cttagatcat aggggcgggg
    21121 tcggcgcaga tggcatcact ggtgatggcg caggtattat gactgaaata ccttttgcat
    21181 ttttcaaaca acatgtaacg gactttgata tccctggtga aggtgaatat gccgtggggt
    21241 tatttttttc caaagaacgc gttttaggtt ctgaacatga agcagttttt aaaaaatatt
    21301 ttgaaggcga agggttatca attcttggtt atcgtaatgt accagttaat aaagatgcca
    21361 ttgctaaaca tgtagcagat acgatgccag tcattcaaca agtgtttatt gatattaggg
    21421 acattgaaga tgttgaaaag catttgtttt tagcgagaaa acaattagag ttttattcga
    21481 ctcagtgcga tttagaattg tattttacga gcttatcacg caaaacaatt gtatataaag
    21541 gttggttacg atcagaccaa attaaaaaac tctatacaga tttatcggat gatttatatc
    21601 aatcaaagct agggttagtg cattcgagat ttagtacgaa tacattcccg agttggaaaa
    21661 gggcacatcc taaccgtatg ttaatgcata atggtgagat taacacgatt aaaggtaatg
    21721 taaactggat gcgagcacgc caacataaat taatcgaaac attatttggc gaggatcaac
    21781 ataaagtgtt tcaaattgtc gatgaggatg gtagtgactc tgctattgta gataatgcgc
    21841 tagagttctt atcgttagcc atggagccag aaaaggcagc gatgttactc atacctgaac
    21901 cttggttata taatgaagcg aatgatgcaa atgtacgtgc gttttatgaa ttttatagtt
    21961 atttaatgga accgtgggat ggtcctacaa tgatttcgtt ctgtaacggt gacaaacttg
    22021 gcgcgcttac agatagaaat ggattacgtc caggtcgtta tacgattact aaagataact
    22081 ttattgtctt ttcatctgaa gtgggtgttg tggacgtacc tgaaaataat gttgctttta
    22141 aaggtcaatt gaatcctgga aagttattgc ttgttgattt taaacagaat aaagtcattg
    22201 aaaataatga tttaaaaggt gcgattgctg gagaattacc atataaagcg tggattgata
    22261 accataaagt tgactttgat tttgaaaata tacaatatca agattcgcaa tggaaagatg
    22321 agacgttatt taaattacaa cgtcagtttg catacacgaa agaagagatt cataagtata
    22381 ttcaggaact tgtagaaggt aagaaggatc ctatcggtgc aatgggatat gatgcgccaa
    22441 ttgcagtgtt gaacgagcga ccagaatcac tatttaatta ctttaaacag ctgtttgcac
    22501 aagttacgaa tccaccaatt gatgcgtatc gtgaaaaaat cgtaacgagt gaactttctt
    22561 atttaggtgg cgaaggtaac ttactagcac ctgatgaaac ggttttagat cgtattcaat
    22621 tgaaaaggcc ggtattgaat gaatcacact tagcagcgat tgatcaggaa cattttaaat
    22681 taacttattt atcaacggta tatgaagggg acttggaaga tgcgttagaa gcattaggcc
    22741 gagaagcagt gaatgctgta aagcaaggcg ctcaaattct agtgttagat gacagtggat
    22801 tagttgatag caatggcttt gcaatgccga tgttactcgc aataagtcat gtgcatcaat
    22861 tacttattaa agcagattta cgtatgtcta caagtttagt cgctaaatct ggtgagacac
    22921 gagaagtgca tcatgttgct tgtttactcg catatggcgc gaatgcaatt gtgccatacc
    22981 tagcgcaacg tacagttgaa caactgacat tgacagaagg gttacaaggc accgttgtcg
    23041 ataatgttaa gacatatacg gatgtattgt cggaaggtgt cattaaagta atggctaaga
    23101 tgggaatttc gacagtgcaa agttatcaag gggcacaaat atttgaagcg attggcttgt
    23161 ctcatgatgt gattgatcgt tattttactg ggacacagtc taagttatct ggtatttcga
    23221 ttgatcaaat tgatgctgaa aataaagcac gtcaacaaag tgatgataat tatcttgcat
    23281 caggtagtac attccaatgg agacaacaag gtcaacatca tgcttttaat ccggaatcta
    23341 ttttcttatt gcagcacgca tgtaaagaaa atgactatgc gcaatttaaa gcatactctg
    23401 aagcggtgaa caaaaataga acagatcaca ttagacattt acttgaattt aaagcatgta
    23461 caccgattga catcgaccaa gttgaaccgg taagtgacat tgtcaaacgc tttaatacag
    23521 gggcgatgag ttatggatcg atttcagcgg aagcacatga aacgttagca caagccatga
    23581 accaattagg tggaaagagt aatagtggtg aaggtggcga agatgcaaaa cgttatgaag
    23641 tacaagttga tggaagcaac aaagtaagtg cgattaaaca agttgcttct gggcggtttg
    23701 gtgtaactag tgattattta caacatgcca aagaaattca aattaaagtt gcgcaaggtg
    23761 caaagcctgg tgaaggtggt caattacctg gtactaaggt atatccgtgg attgcgaaga
    23821 caagagggtc aacgccaggt atcggtctga tttcaccacc gccacatcat gatatttatt
    23881 caatagaaga tttagcgcaa ctgatacatg atttgaaaaa tgcgaataaa gatgcagata
    23941 tcgcggtaaa attagtttcg aaaacaggtg ttggtaccat tgcatctggg gtggcaaaag
    24001 catttgcaga taaaattgtc atcagtggtt acgatggtgg tacaggggct tcacctaaaa
    24061 cgagtattca gcatgccggt gttccttggg agattggttt agcagaaaca catcaaacat
    24121 taaaactaaa tgacttaaga agtcgtgtta agttagaaac agacggtaag ttattaactg
    24181 gtaaagatgt agcgtacgca tgtgcgcttg gagcggaaga atttggattt gcaactgcac
    24241 cattagtggt gttgggctgt ataatgatgc gtgtatgcca taaagataca tgtccagtag
    24301 gagttgcaac tcaaaacaaa gatttacgtg ctttatatag aggtaaagca catcatgttg
    24361 ttaattttat gcattttatt gcacaagaat taagagaaat tttagcatct ttaggtttga
    24421 aacgtgtaga agacttagtt ggaagaactg atttattaca acgatcatca acattaaaag
    24481 cgaatagcaa agcggctagt attgatgttg aaaaactgtt atgtcctttc gatgggccaa
    24541 acacaaaaga aattcaacaa aatcataatc ttgagcatgg atttgattta acaaatttat
    24601 atgaagtaac gaagccatat attactgaag ggcgtcgcta tacaggtagc tttacagtaa
    24661 ataatgaaca acgtgatgta ggagttatta caggtagtga gatttcgaaa caatatggag
    24721 aagcaggact tcctgaaaat acaattaatg tttatacgaa tggtcatgct ggtcaaagtc
    24781 ttgcagcata cgcaccgaaa ggcttaatga ttcatcatac tggagatgcg aatgactatg
    24841 ttggtaaagg attatctggt ggtacggtca ttgtcaaagc accttttgaa gaacgacaaa
    24901 atgaaattat tgctggtaac gtctcattct atggtgcgac aggtggtaag gcatttatta
    24961 acggtagtgc aggagaaaga ttctgtatta gaaatagtgg tgtagatgtt gtcgttgaag
    25021 gtatcggcga ccatggatta gagtacatga ctggtggaca tgtcattaat ttaggtgatg
    25081 taggtaagaa cttcggtcaa ggtatgagtg gtggtattgc ttacgttatc ccgtctgatg
    25141 tagaagcttt tgttgaaaat aatcaactag atacgctttc gtttacaaag attaaacacc
    25201 aagaagaaaa agcattcatt aagcaaatgc tggaagaaca tgtgtcacac acgaatagta
    25261 cgagagcgat tcatgtgtta aaacattttg atcgcattga agatgtcgtc gttaaagtta
    25321 ttcctaaaga ttatcaatta atgatgcaaa aaattcattt gcacaaatca ttacatgaca
    25381 atgaagatga agcgatgtta gctgcatttt acgatgacag taaaacaatc gacgctaaac
    25441 ataaaccagc cgttgtgtat taaggaaagg gggagatacg atgggtgaat ttaaaggatt
    25501 tatgaagtat gacaaacagt acttaggtga attatcactg gtagaccgtt tgaagcatca
    25561 taaagcatat caacaacgat ttactaaaga agatgcctct atccaaggtg cgcgatgtat
    25621 ggattgtgga acgccgtttt gtcaaaccgg acaacagtat ggtagggaaa caataggttg
    25681 tccaattgga aactacattc ctgaatggaa cgacttagtg tatcatcaag attttaaaac
    25741 tgcttatgaa cgcttaagcg aaacaaataa ctttcctgac tttacagggc gtgtatgtcc
    25801 tgcaccatgc gaaagtgctt gtgtgatgaa gattaataga gaatcgattg cgattaaagg
    25861 tattgaacgc acaattattg atgaagcttt tgaaaatggt tgggtagcgc cgaaagttcc
    25921 gagtcgccgt agagatgaaa aagtggcaat cgttggaagc ggtccagcag gattaactgc
    25981 tgctgaagaa cttaatctac taggatatca agtaactatt tatgaacgtg ctagagaatc
    26041 aggcggttta ttaatgtatg gtattccgaa tatgaaactt gataaagatg tggttcgacg
    26101 tcgtattaag ttaatggaag aagcgggcat tactttcatt aatggtgttg aagtaggcgt
    26161 tgatattgat aaagcaacgt tagaatctga gtatgatgcc attatattat gtactggtgc
    26221 acaaaaaggt agagatttac ctttagaagg acgcatgggt gatggtatac atttcgctat
    26281 ggattattta actgaacaaa cgcagctgtt aaatggagaa attgatgata ttacaataac
    26341 tgcaaaagat aagaatgtca ttatcattgg tgctggtgat acaggggcag actgtgtagc
    26401 gacagcatta agagaaaatt gtaaatcgat tgttcaattt aataaatata cgaaattgcc
    26461 agaagcaatt acatttacag aaaatgcatc atggccttta gcaatgccgg tgtttaaaat
    26521 ggactatgcg caccaagagt acgaagctaa gtttggtaag gaaccacgtg catatggtgt
    26581 tcaaacaatg cgttacgatg ttgacgataa aggacacata cgtggtttgt atactcaaat
    26641 tttagagcaa ggcgaaaatg gtatggtcat gaaagaagga cctgaaagat tttggcctgc
    26701 tgaccttgta ttattatcaa tcggcttcga aggtacagaa ccaactgtac cgaatgcttt
    26761 taacattaaa acggatagaa atcgaatcgt ggcggatgat acaaactatc aaactaataa
    26821 tgaaaaagta tttgctgctg gagatgctag acgtggtcaa agtttagttg tatgggcgat
    26881 taaagaaggt agaggcgtag cgaaagcagt agatcagtat ttagcgagta aagtttgtgt
    26941 ataatctttg tatggaaatg gtggttacgt tgacgttgtg gcatgctgaa tcgagtttga
    27001 aataatctag tatctatcaa cgtcacatgc tatcattgta acctaaaaac aaaggtttgt
    27061 aagacaacaa atagattaat tataagtagt gattttttac attcgtttat aggtcaactg
    27121 tagtggaaga caatgatttg tggtaatcat gtaatgctta aaaacaatat tgacttttac
    27181 agaacgttca tatatgataa atattgtgtt taggaggaat acccaagtcc ggctgaaggg
    27241 atcggtcttg aaaaccgaca ggggcttaac ggctcgcggg ggttcgaatc cctcttcctc
    27301 cgccatcaat atttatatta aatactatat ataatgaagg taagtgctca aattttgagt
    27361 atttaccttt tttatttgtc tttgaatgac tcgtaatttt tgataataga aatgataagg
    27421 cattgagatt ggaagggcat ttggcttgtg caatatacat agctaaatgt cttttttgtt
    27481 ttgtgaaata tgatggatgg cttgtgtgga caagtttgct atttatagat atgcattttt
    27541 caatttagga gttggccatg catctacact ttataatggt gagagcgtgg tgaggtattg
    27601 ttaataacgc aattgtagcg aggagttatt gctacatatg tcgttatggc tcattgattt
    27661 tctgaaatgg ctatcccaga taattgtgac aaaataaaaa tatttctttg aaagccttta
    27721 cataacttgt ctagacaagt tatactcatt ttaagacatt aagggagtga aatatatggc
    27781 tgtaaaaaga gaagatgtaa aagccatcgt aaccgctatt gggggaaaag aaaatcttga
    27841 agctgcaacg cattgtgtaa cacgattacg tttagtgctg aaggatgaaa gtaaagttga
    27901 taaagacgca ttaagtaata acgcgttggt caaggggcag tttaaagcag accatcaata
    27961 tcaaattgtc attggtccag gaacagtcga tgaagtgtat aagcagttta ttgatgaaac
    28021 aggtgctcaa gaagcttcga aagatgaagc gaaaaaagca gctgcacaaa aagggaatcc
    28081 agtacaacgt ttgatcaaat tgttggggga tatttttata ccaatattac ctgcgattgt
    28141 gacagctggt ttgttaatgg gaatcaataa tttacttaca atgaaaggtt tatttggtcc
    28201 aaaagcactt attgagatgt atccacaaat tgctgatatt tcaaacatca ttaatgtgat
    28261 tgcgagtacg gcatttattt tcttaccagc attaattggt tggagtagta tgcgtgtatt
    28321 tggtggtagt ccgattctag gcatagtctt aggtttgatt ttaatgcatc cgcaattagt
    28381 atctcagtat gatttggcaa aagggaatat tccgacgtgg aacttatttg gcttagagat
    28441 taagcagttg aattaccaag gtcaagtgtt gccagtttta attgcagctt atgttctagc
    28501 taaaattgaa aaaggattaa ataaagtcgt tcacgattcg ataaaaatgt tggtcgttgg
    28561 acccgtagcg cttttagtta ctggattttt agcatttatt atcattggac cagttgcgtt
    28621 attgattggt acaggtatta catctggtgt tacatttata ttccaacatg caggatggct
    28681 tggcggagca atatatggat tgttatatgc accacttgta attacaggac tacaccatat
    28741 gtttttagca gtagatttcc aattgatggg tagcagctta ggcggtacgt atttatggcc
    28801 aattgttgcg atttccaata tttgtcaggg ctctgcagca tttggagcat ggtttgtcta
    28861 taaacgtcgt aaaatggtta aagaagaagg cttggcatta acatcttgta tttctggtat
    28921 gttaggtgtt actgaaccag ctatgtttgg tgtgaactta cctctgaaat atccatttat
    28981 cgctgcgata tcaacgtctt gtgtattggg ggcaatcgtt ggtatgaata acgtacttgg
    29041 aaaagttggt gttggtggcg tgccagcatt catttcaatt caaaaagaat tttggccagt
    29101 atatcttatt gtgacagcta ttgctattgt tgtaccatgt atactaacaa ttgtgatgtc
    29161 tcattttagt aaacaaaaag cgaaagaaat tgttgaagat taataaaata aaaaaggggc
    29221 gttcgttatt tggacgtcct ttattacgtt ataaggtggt aattgtgtgt cgaaagaaat
    29281 agattggaga aaatccgttg tatatcaaat ttatcctaag tcgtttaatg atacgacggg
    29341 gaatggtata ggagatatca acggaattat agaaaaattg gattatatca agttattggg
    29401 tgttgattat atttggttaa caccagtgta tgaatcaccg atgaatgata atggctatga
    29461 tatcagcaat tatttagaaa tcaacgaaga ctttggaacg atggatgatt ttgaaaagtt
    29521 aatcaaagtt gctcatcaaa aagacttgaa agtgatgtta gatattgtca ttaatcatac
    29581 gtcgacggag catgaatggt ttaaagaagc ccgtaaatct aaagataacc cttatagaga
    29641 ttattacttt ttcagatcat ctgaagacgg gccgccaaca aattggcatt ctaaattcgg
    29701 tggtaatgca tggaagtatg attctgagac agatgaatat tatttacatt tatttgatgt
    29761 cagtcaagct gatttaaatt gggataatcc ggaagtacgt caatcgttat atcgcatagt
    29821 caatcattgg atagacttcg gcgttgatgg ttttcgattt gatgtcatta acttaatttc
    29881 taaaggtgaa tttaaggact ctgacaaaat aggtaaagaa ttttatacgg atggtcctag
    29941 agtgcatgag tttctgcatg aattaaatcg tcaaacgttt ggtaacactg acatgatgac
    30001 tgtaggagaa atgtcttcga cgacgattga aaattgtatt aagtatacac agccagaacg
    30061 ccaagaattg aatagtgttt ttaattttca tcatctaaag gttgattatg ttgatggtga
    30121 aaagtggaca aatgcgaagc ttgattttca taagttaaag gaaattctga tgcaatggca
    30181 acgaggtatt tatgacggtg gcggatggaa cgcgattttc tggtgtaatc atgatcagcc
    30241 acgggtagtg tctagatttg gtgatgatac gtcggaagag atgaggatac aaagtgctaa
    30301 aatgttagct atcgcactgc atatgttgca agggacgcta tatatttacc aaggggaaga
    30361 aattggtatg acggacccac attttacatc aatagcacaa tatcgcgatg ttgaatcgat
    30421 taatgcctac catcagttgt taagtgaagg gcatgctgaa gcggatgtat tagcgatttt
    30481 aggacagaag tcacgagaca attcgagaac gcctatgcaa tggagtgatg atgttaatgc
    30541 tggatttaca gctggtaagc cttggattga tatttcggaa aattatcatc aggtcaacgt
    30601 tagacaagca cttcagaata aagattctat tttctacacg tatcaaaaat taatacaatt
    30661 aagacatacg catgatatta ttacgtatgg agacattgtg ccacgtttta tggatcatga
    30721 tcatttattt gtttatgaac gtcattataa gaatcaacaa tggctagtaa ttgcgaattt
    30781 ctcagcatcg gctgttgatt tgccagaagg attggctaga gaaggtcgtg ttgtgattca
    30841 aacaggcaca gtggaaaata atacgataag cgggtttggt gcaattgtaa tcgaaacaaa
    30901 cgcgtaaaat aaattgagtg gatgcgttta tatggcgaaa caaaaaaagt ttatgaagat
    30961 ttatgaggcg ttgaaagaag atatattaaa cgggcagatt caatatggtg aacaaattcc
    31021 gtctgaacat gatttggtgc aattgtacca gtcatctcga gagaccgtgc gtaaggcatt
    31081 agatttgttg gcattagacg gcatgattca aaagattcat ggtaaagggt cacttgtcat
    31141 ttatcaggag gttacagagt ttccattttc tgaacttgtt agttttaaag aaatgcaaga
    31201 agaaatgggc gtcgcatatt taactgaagt tgttgtgaat gaggttgttg aagcgcatga
    31261 agttccagaa gttcaacatg ctttaaacat caattctagt gaatcactca ttcatattgt
    31321 tagaactcgt cggcttaacc aacatgtgaa gattgttgat gaagattatt ttctaaagtc
    31381 gattgtttca gatataggta atgatgttgc gagtgattct atttatgatt atttggaaaa
    31441 ggtattaaat cttaatatta gttattcaag taagtctatt acttttgaac cgtttgatga
    31501 acaagcatat caattgtttg gtgatgtatc ggtggcttat tcagcaacag ttcgaagtat
    31561 tgtgtattta gaaaatacaa tgccgtttca atataatatt tcaaaacatc ttgcaaatga
    31621 atttaaattt aatgacttct caagacgtcg tacaaagtaa acaatgatat aaatgattta
    31681 tacttgcaat taactattaa aatatagtaa tatatatctt gccgtgctag gtggggaggt
    31741 agcggttccc tgtactcgaa atccgcttta tgcgaggctt aattcctttg ttgaggccgt
    31801 atttttgcga agtctgccca aagcacgtag tgtttgaaga tttcggtcct atgcaatatg
    31861 aacccatgaa ccatgtcagg tcctgacgga agcagcatta agtggatcat catatgtgcc
    31921 gtagggtagc cgagatttag ctaacgactt tggttacgtt cgtgaattac gttcgatgct
    31981 taggtgcacg gttttttatt ttttaaatat taaaccgatt attaagagtt gaaaatatat
    32041 atttatttat agaagctact ttcttgaaga caattcagcg tattatacgt ggaacatgtt
    32101 tgtgggaagt agctttttta tatgtgaagt ttgattcaag tgaactcgat gtacagtttg
    32161 aatgattttt gtgtcaatga aaagtaagaa gttataattt gatgataaag aaatgatggt
    32221 gaaatgaggg ggagtatctt acaatagaat tattaatgag atacgttatg attattgaca
    32281 atcaaatgcc tacggaggac atatgcaaat atatttaagt actttaacag agttagatta
    32341 tgataaatct ttaaatagta ttgaagaaag ttttgatgat aatcctgaaa cgagttggca
    32401 agcacgtgcg aaagtaaaac atttaagaaa atctccttgc tataattttg aattagaagt
    32461 aatagcgaaa aatgaaaata acgatgtcgt tggacacgtt ttattaattg aagtagaaat
    32521 taatagtgat gataagacgt attatggttt ggcgattgcc tctttatcag ttcatcctga
    32581 attacgtgga caaaaattag gtcgtggctt ggttcaagca gtagaagagc gtgccaaagc
    32641 acaagagtat agtacggttg ttgtagacca ttgttttgac tactttgaaa agttgggtta
    32701 tcaaaatgct gctgagcatg acattaaatt agaatctggt gatgcaccgt tacttgtaaa
    32761 atatttatgg gataatttga cggatgcacc acacggaatc gtaaaatttc cagaacattt
    32821 ttattaattg ttcaattaag aagtaaaggt attatcatgc tataatgaga ggtaattgtt
    32881 tatggaggtg ctaacttgaa ttatcaagcc ttatatcgta tgtacagacc ccaaagtttc
    32941 gaggatgtcg tcggacaaga acatgtcacg aagacattgc gcaatgcgat ttcgaaagaa
    33001 aaacagtcgc atgcttatat ttttagtggt ccgagaggta cggggaaaac gagtattgcc
    33061 aaagtgtttg ctaaagcaat caactgttta aatagcactg atggagaacc ttgtaatgaa
    33121 tgtcatattt gtaaaggcat tacgcagggg actaattcag atgtgataga aattgatgct
    33181 gctagtaata atggcgttga tgaaataaga aatattagag acaaagttaa atatgcacca
    33241 agtgaatcga aatataaagt ttatattata gatgaggtgc acatgctaac aacaggtgct
    33301 tttaatgccc ttttaaagac gttagaagaa cctccagcac acgctatttt tatattggca
    33361 acgacagaac cacataaaat ccctccaaca atcatttcta gggcgcaacg ttttgatttt
    33421 aaagcaatta gcctagatca aattgttgaa cgtttaaaat ttgtagcaga tgcacaacaa
    33481 attgaatgtg aagatgcagc cttggcattt atcgctaaag cgtctgaagg gggtatgcgt
    33541 gatgcattaa gtattatgga ccaagctatt gcatttggtg atggtacgtt aacattgcaa
    33601 gatgcgttga atgtcacagg tagcgtacat gatgaagcgt tggatcactt gtttgatgat
    33661 attgtacaag gtgacgtaca agcatctttt aaaaaatacc atcagtttat aacagaaggt
    33721 aaagaagtga atcgcctaat aaatgatatg atttattttg tcagagatac gattatgaat
    33781 aaaacatctg agaaagatac tgagtatcga gcactgatga acttagaatt agatatgtta
    33841 tatcaaatga ttgatcttat taatgataca ttagtgtcga ttcgttttag tgtgaatcaa
    33901 aacgttcatt ttgaagtgtt gttagtaaaa ttagctgagc agattaaggg tcaaccacaa
    33961 gtgattgcga atgtagctga accagcacaa attgcttcat cgccaaacac agatgtattg
    34021 ttgcaacgta tggaacagtt agagcaagaa ctaaaaacac taaaagcaca aggagtgagt
    34081 gtcgctccta ctcaaaaatc ttcgaaaaag cctgtgagag gtatacaaaa atctaaaaat
    34141 gcattttcaa tgcaacaaat tgcaaaagtg ctagataaag cgaataaggc agatatcaaa
    34201 ttgttgaaag atcattggca agaagtgatt gatcatgcca aaaacaatga taaaaaatca
    34261 ctcgttagtt tattgcaaaa ttcggaacct gtggcggcaa gtgaagatca cgtacttgtg
    34321 aaatttgagg aagagatcca ttgtgaaatc gtcaataaag acgacgagaa acgtagtagc
    34381 atagaaagtg ttgtatgtaa tatcgttaat aaaaacgtta aagttgttgg tgtaccatca
    34441 gatcaatggc aaagagttcg aacggagtat ttacaaaatc gtaaaaacga aggcgatgat
    34501 atgccaaagc aacaagcgca acaaacagat attgctcaaa aagcaaaaga tcttttcggt
    34561 gaagaaactg tacatgtgat agatgaagag tgatacatga caagcgatat aatcgtatgt
    34621 ataatgaaag aaacatcatt ttattgataa atatttattg attttcaagg aggaaatgga
    34681 atatgcgcgg tggcggaaac atgcaacaaa tgatgaaaca aatgcaaaaa atgcaaaaga
    34741 aaatggctca agaacaagaa aaacttaaag aagagcgtat tgtaggaaca gctggcggtg
    34801 gcatggttgc agttactgta actggtcata aagaagttgt cgacgttgaa atcaaagaag
    34861 aagctgtaga cccagatgat attgaaatgc tacaagactt agtgttagca gctactaatg
    34921 aagcgatgaa taaagctgat gagcttactc aagaacgttt aggtaaacat actcaaggct
    34981 taaacatccc tggaatgtga tcatagatgc attatccaga acctatatca aaacttattg
    35041 atagctttat gaaattgcca ggcattggtc caaagacagc ccaacgtctg gcttttcata
    35101 ccttagatat gaaagaagac gatgttgttc agtttgccaa agcattagta gatgttaaaa
    35161 gagaattaac atattgtagc gtatgtggtc acattactga aaatgatcca tgttatattt
    35221 gtgaagataa gcaaagagat cgttcagtta tttgtgttgt ggaagatgac aaagatgtca
    35281 tagctatgga aaaaatgaga gaatacaaag gtttatatca cgttttacat gggtctattt
    35341 cgcctatgga tggcattgga ccagaagata ttaatattcc ttcattgatt gaacgcttaa
    35401 aaagcgatga agttagcgaa ttaatcttag ctatgaaccc gaacttagag ggggaatcta
    35461 cagccatgta tatttctaga ttagttaagc ctataggtat caaagtgacg agattagcac
    35521 aagggttatc ggtaggtggc gatttagagt atgctgacga agtaacttta tctaaagcaa
    35581 tcgcaggtag aacagaaatg taatgtcttc tattaaacat ttttgaattt aatactatag
    35641 taagaaaagt cacagtgtaa tcattgtggc tttttttatg gtgtggtgtg atgtactact
    35701 ttatttgcgg tgtggcggtg gtatggttta cctagtttta ctgagggatg ggtaatcttt
    35761 aggaagcaag ccgttggttg tgatttgtta cttctaatag taatgatgtg aattggatta
    35821 tcgaattaga tctacggtta tggtgtgttg gtgctattaa tttgataaat gcggttgatg
    35881 gttaatgact atgcaaatga aattcttttg taattgaaat gatagatgct ggcttagtag
    35941 ttgtacttct ttggtctaaa gtttattaaa tcagcctgta tagcggtgtt ttgagaggtt
    36001 atttaaaact tgtaaattta tttttaattt ctggtaaaaa ataaagttct gttttgcggt
    36061 ttttttgatt gatatggtta gagaaaaatc tgtttcttgt tctaaaaaac gtactattta
    36121 taagtgggga ttttttaagt tcgattttta ggataagggc gttcagtaca gatggcaaag
    36181 gtgtaatttt tactgttgtt aagcagtttg aaagcctgta tagtatttat ttgttgaggc
    36241 aaacaaaaca actcaactta agaaataact tgaattacta acgaaaatta attttaaaaa
    36301 gttgttgact taaatgttaa taaaatgtat aattaattct tgtcggtaag aa
//
LOCUS       DAPSKH010000024        36291 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPSKH010000024 DAPSKH010000000
VERSION     DAPSKH010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36291
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.024"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            93..1211
                     /gene="ald"
                     /locus_tag="RPH49_001263"
     CDS             93..1211
                     /gene="ald"
                     /locus_tag="RPH49_001263"
                     /EC_number="1.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
                     /protein_id="HDY5124426.1"
                     /translation="MLVAVVKELKQGEGRVACTPENVRKLTDAGHKVIVEKNAGIGSG
                     FSDDMYEKEGAKIVTHEQAWEADLVIKVKEPHTSEYQYFKKDQIIWGFLHLASSKEIV
                     EKMQEVGVTAISGETIIKNGKAELLAPMSAIAGQRSAIMGAYYSEAQHGGQGTLVTGV
                     HENVDIPGSTYVIFGGGVAATNAANVALGLNAKVIIIELNDDRIKYLQDMYAEKDVTV
                     VKSTPENLAEQIKKADVFISTILIPGAKPPKLVTREMVKSMKKGSVLIDIAIDQGGTI
                     ETIRPTTISDPVYEEEGVIHYGVPNQPGAVPRTSTMALAQGNIDYILEICDKGLEQAI
                     KDNEALSTGVNIYQGQVTNQGLATSHDLDYKEILNVIE"
     gene            1306..2346
                     /gene="tdcB"
                     /locus_tag="RPH49_001264"
     CDS             1306..2346
                     /gene="tdcB"
                     /locus_tag="RPH49_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDY5124427.1"
                     /translation="MTTNTVTLQTAHIVSLGDIEEAKASIKPFIRRTPLIKSMYLSQS
                     ITKGNVFLKLENMQFTGSFKFRGASNKINHLTDEQKEKGIIAASAGNHAQGVALTAKL
                     LGIDATIVMPETAPQAKQQATKGYGAKVILKGKNFNETRLYMEELAKENGMTIVHPYD
                     DKFVMAGQGTIGLEILDDIWNVNTVIVPVGGGGLIAGIATALKSFNPSIHIIGVQSEN
                     VHGMAESFYKRDLTEHRVDSTIADGCDVKVPGEQTYEVVKHLVDEFILVTEEEIEHAM
                     KDLMQRAKIITEGAGALPTAAILSGKINNKWLEDKNVVALVSGGNVDLTRVSGVIEHG
                     LNIADTSKGVVG"
     gene            2377..3699
                     /locus_tag="RPH49_001265"
     CDS             2377..3699
                     /locus_tag="RPH49_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5124428.1"
                     /translation="MSNGKELQKNIGFFSAFAIVMGTVIGSGVFFKISNVTEVTGTAG
                     MALFVWFLGGIITICAGLTAAELAAAIPETGGLTKYIEYTYGDFWGFLSGWAQSFIYF
                     PANVAALSIVFATQLINLFHLSIGSLIPIAIASALSIVLINFLGSKAGGILQSVTLVI
                     KLIPIIVIVIFGIFQSGDITFSLIPTTGNSGNGFFTAIGSGLLATMFAYDGWIHVGNV
                     AGELKNPKRDLPLAISVGIGCIMAVYLLINATFLLTLPIELLAGNLNAASDTSKILFG
                     ENGGKIITIGILISVYGTINGYTMTGMRVPYAMAERKLLPFSHLFAKLTKSGAPWFGA
                     IIQLIIAIIMMSMGAFDTITNMLIFVIWLFYCMSFVAVIILRKREPNMERPYKVPLYP
                     IIPLIAILAGSFVLINTLFTQFILAIIGILITALGIPVYYYKKKQKAA"
     gene            3855..5246
                     /gene="norB"
                     /locus_tag="RPH49_001266"
     CDS             3855..5246
                     /gene="norB"
                     /locus_tag="RPH49_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter NorB"
                     /protein_id="HDY5124429.1"
                     /translation="MEKPSREAFEGNNKLLIGIVLSVITFWLFAQSLVNVVPILEDSF
                     NTDIGTVNIAVSITALFSGMFVVGAGGLADKYGRIKLTNIGIILNILGSLLIIISNIP
                     LLLILGRLIQGLSAACIMPATLSIIKSYYIGKDRQRALSYWSIGSWGGSGVCSFFGGA
                     VATLLGWRWIFILSIIISLIALFLIKGTPETKSKSISLNKFDIKGLVLLVIMLLSLNI
                     LITKGSELGVTSLLFITLLAIAIGSFSLFIVLEKRATNPLIDFKLFKNKAYTGATASN
                     FLLNGVAGTLIVANTFVQRGLGYSSLQAGSLSITYLVMVLIMIRVGEKLLQTLGCKKP
                     MLIGTGVLIVGECLISLTFLPEILYVICCVIGYLFFGLGLGIYATPSTDTAIANAPLE
                     KVGVAAGIYKMASALGGAFGVALSGAVYAIVSNMTNIYTGAMIALWLNAGMGILSFVI
                     ILLLVPKQNDTQL"
     gene            5644..>36291
                     /gene="ebh"
                     /locus_tag="RPH49_001267"
     CDS             5644..>36291
                     /gene="ebh"
                     /locus_tag="RPH49_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyperosmolarity resistance protein Ebh"
                     /protein_id="HDY5124430.1"
                     /translation="MNYRDKIQKFSIRKYTVGTFSTVIATLVFLGFNTSQAHAAETNQ
                     PASVVKQKQQSNNEQTENRESQVQNSQNSQNGQSLSATHENEQPNINQTNHVDVSAEQ
                     SSTTENEQAVSQNKQTKKDTADATPTQSAKAESKHEQNESRSANKKENDNKAAHVENH
                     EANVVTASDSPDNGNVQHDRNELQAFFDANYHDYRFIDRENADSGTFNYVKGIFDKIN
                     TLLGSNDPINNKDLQLAYKELEQAVALIRTMPQRQQTSRRSSRIQTRSVESRAAEPRS
                     VSSYQNADSSYYVENANDGSGYPVGTYINASNKGAPFYLPTAPWNTLKASAAKEIVLI
                     TAKQTGDGYQWVIKFNKGHAPHENMIFWFALPSDQVPVGRTDFVTVNADGTNVQWSNG
                     AGAGAYKPLPQMWPYGVNDSRSRDFKIRNRSGQVIYDWTDVHVNTLRDLARAGDYFSE
                     AGAPAATKAIGEQTFRYINGERPTESPGASKVYTFIGAGDASYTISFKTQGPTTNKLY
                     YAAGGRALEYNQLFMYSQLYVESTQDHQQRLDGFRQVVNRSYRLGTTKRVEVSQGNIQ
                     TKKVLESTNLNIDDFMDDPLSYVKTPSNKVLGFYPTNANPNAYRHGGTNPLNEYQLSQ
                     LFTDDKLQQAARTGNPIRLMIGFDYPDGHGNAETLVPVNLTVLPEIQHNIKFYKNDDT
                     QNIADKPASRQAGHPIFYVYAGNQGNASVNLGGSVTSIQPLRINLTSSENFTDRDWQI
                     TGIPRTLHIENSTNRPNNARERNIELVGNLLPGDYFGTIRFGRKEQLFEIRVKPHTPT
                     ITTTAEQLRGTALQKVPITVTNIPLDPSSLVYIVYPTDQTRDGGSEADQMPSNYSILA
                     TGTPDGVHNTITIQPKDYTVFIPPVGKQIRALIYYNKVVASNMSNAVTILPDDIPPTI
                     NNPVGLNAKYYRGDEVNFTMGVSDRHSGIKNTTITTLPNGWTSNLTKADKNNGSLSIT
                     GRVSMNQAFNSDITFKVSATDNVNNTTNDSQSKHVTVHVGKISEDAHPIVLANSEKVV
                     VVNPTSVSNDEKQRIITAFMNKNQNIRGYLASSNPVTVDNNGNVTLHYRDGSSTTLDA
                     TNVMTYEPVVKPEYQTANAPKTATVTIAKGQSFSIGDIKQYFTLSNGQAIPNGTFTNI
                     TSDRTIPTAQEVSQMNAGTQLYHIVASNAYHKDTEDLYISLKIIDVKQPEGDQRVYRT
                     STYDLTTDEISKVKQAFINANRDAITFAEGDISVTNTPNGANVSTVTVNINKGRLTKS
                     FTSNLANMNFLRWVNFPQDYTVSWTNAKIASRPTDGGLSWSDDHKSLIYRYDATLGTP
                     ITTNDILTMLKATTTVPGLRNNIAGNEKTQAEAGGRPNYRPTGYSQANASSDGQRQYT
                     LNGQVIQVLDIINPTNGFGGQTITNSNVRANHSNSTVVSVNEPAANGAGAFTIDHVVK
                     NNTTHNAADAVYKAQLYLSPYGPKQYVEHLNQNTGNTTDAINIYFVPSDLVNPTISVG
                     NYANHQVFSGETFTNTITANDNFGVQSVTVPNTSQITGTVDNNHQHVSATAPNVTSAT
                     NKTINLVATDTSGNTATTSYNVTIKPLRDKYRVGTSSTAANPVRIANISNNAIVSQAD
                     QTAIINSLTFTETVPNRSYARASANEITSKTVSNVSRTGNNANVTVTVTYQDGTTSTV
                     TVPVKHVIPEIVAHSHYTVQGQDFPAGNGSSASDYFKLSNGSAIPDATITWVSGQAPN
                     KDNTRIGEDITVTAHILIDGETTPITKTATYKVVRTVPKHVFETDRGVLYPGVSDMYD
                     AKQYVKPVNNSWSTNAQNMNFQFVGTYGPNKDVVGISTRLIRITYDNRQTEELTILSK
                     VKPDPPRIDGNSVTYKAGLTNQEVKVNNVLSNSTVKLFKADNTPLNVTNIIHGSGYSS
                     VVTVSDALPNGGIKAKSSISMNNVTYTTQDEHGQVVTVTRNESVDSNDSASVTVTPQL
                     QATTEGAVFIKGGDGFDFGHVERFIQNPPHGATVAWHDNPDTWKNTVGNTHKTAVVTL
                     PSGQGTRNVEVPVKVYPVANAKALSRDVKGQNLTNGTDAMSYITFDPNTNTNGITAAW
                     ANRQQPNNQQAGVQHLNVDVTYPGISAAKRVPVTVNVYQFEFPQTTYTTTVGGTLASG
                     TQASGYAHMQNATGLPTDGFTYKWNNAATGTNDANWAAMNKPNAAKVVNAKYDVIYNG
                     HTFATSLPAKFVVKDVQPAKPTVTETAAGAITIAPGANQTVNTHAGNVTTYADKLVIK
                     RNGSVVTTFTRHNNTSPWVKEASATNVTGIVGTNNGITVAAGTFNPADTIQVVATQGS
                     GETISDEQRSDDFTVVAPQPNQATTKIWQNGHIDITPNNPSGHLINPTQAMDIAYTEK
                     VGNGAEHSKTINVVRGQNNQWTIANKPDYVTLDAQTGKVTFNANTIKPNSAITITPKA
                     GTGHSASSNPSTLTAPAAHTVNTTEIVKDYGSNVTASEINNAVQVANKRTATIKNGTA
                     MPTNLAGGSTTTIPVTVTYNDGSTEEVQESIFTKADKRELITAKNHLDDPVSTDGKKP
                     GTITQYNNAMHNAQQQINAAKTEAQQVINNERATPQQVNAALSKVQAAQTKINEAKAL
                     LQNKEDNSQLVTSKNNLQSSVNQVPSTAGMTQQSIDNYNAKKREAESEITAAQRIIDN
                     GDATAQQISDEKHRVDNALTALNQAKHDLTADTHALEQAVQQLNRTGTTTGKKPASIT
                     AYNNSIRALQSDLTSAKNSANAIIQKPIRTVQEVQSALTNVNRVNERLTQAINQLVPL
                     ADNSTLRTAKTKLDEEINKSVTTDGMTQSSIQAYENAKRAGQTESTNAQNVINNGDAT
                     DQQIAAEKAKVEEKYNSLKQAIAGLTPDLAPLQTAKTQLQNDIDQPTSTTGMTSASVA
                     TFNEKLSAARTKIQEINRVLASHPDVATIRQNVTAANAAKSALDQARNGLTVDKAPLE
                     NAKNQLQHSIDTQTSTTGMTQDSINAYNAKLTAARNKIQQINQVLAGSPTVDQINTNT
                     SAANQAKSDLDHARQALTPDKTPLQNAKTQLEQSINQPTDTTGMTTASLNAYNQKLQA
                     ARQKLTEINQVLNGNPTVQNINDKVAEANQAKDQLNTARQGLTLDRQPALTTLHGASN
                     LNQAQQNNFTQQINAAQNHAALETIKSNITALNTAMTKLKESVADNNSIKSGQNYTDA
                     TQANKQAYDNAVNAAKGVIGETNNPTMDVNTVNQKAASVKSTKDALDGQQNLQRAKTE
                     ATNAITHASDLNQAQKNALTQQVNSAQNVQAVNNIKQTTQSLNTAMTGLKRGVANHNQ
                     VVQSDNYVNADTNKKNDYNNAYNHANDIINGNPQHPVITPSDVNNALSNVTSKEHALN
                     GEAKLNTAKQEANTALGQLNNLNNAQRQNLQSQINGAHQIETVNTIKQNATNLNSAMG
                     NLRHAVADKEQVKRTEDYADADTAKQNAYNSAVSSAETIINQSTNPTMSVDDVNRATL
                     AVTTNKTALNGDEKLAQSKTDAARAIDALPHLNNAQKADVKSKINAASNIAGVNTVKQ
                     QGTDLNTAMGNLQGAINDEQTTLNSQNYQDATPSKKTAYTNAVQAAKDILNKSNGQNK
                     TKDQVTEAMNQVNSAKNNLDGTRLLDQAKQTAKQQLNNMTHLTTAQKTNLTNQINSGT
                     TVAGVHTVQSNANTLDQAMNTLRQSIANKDATKASEDYVDANNDKQTAYNNAVAAAET
                     IINANSNPEMNPSTITQKAEQVNSSKTALNGDENLATAKQNAKTYLNTLTSITDAQKN
                     NLISQISSATRVSGVDTVKQNAQHLDQAMASLQNGINNESQVKSSEKYRDADTNKQQE
                     YDNAITAAKAILNKSTGPNTAQNAVEAALQRVNTAKDALNGDAKLIAAQNAAKQHLGT
                     LTHITTAQRNDLTNQISQATNLAGVESVKQSANSLDGAMGNLQTAINDKSGTLASQNF
                     LDADEQKRNAYNQAVSNAETILNKQTGPNTAKTAVEQALNNVNSAKHALNGTQNLNNA
                     KQAAITAINGASDLNQKQKDVLKAQANGAQRVSNAQDVQRNATELNTAMGTLKHAIAD
                     KTNTLASSKYVNADSTKQNAYTTKVTNAEHIISGTPTVVTTPSEVTAAANQVNSAKQE
                     LNGDERLRVAKQNANTAIDALTQLNTPQKAKLKEQVGQANRLEDVQTVQTNGQSLNNA
                     MKGLRDSIANETTVKASQNYTDASPNNQSTYNSAVSNAKGIINQTNNPTMDTSAITQA
                     TTQVNNAKNGLNGAENLRNAQNTAKQNLNTLSHLTNNQKSAISSQIDRAGHVSEVTAA
                     KNAATELNTQMGNLEQAIHDQNTVKQSVNFTDADKAKRDAYTNAVSRAETILNKTQGA
                     NTSKQDVEAAIQSVTSAKNALNGDQNVTNAKNTAKHALNNLTSINNAQKRNLTTKIDQ
                     ATTVAGVEAVSNTGTQLNTAMANLQNGINDKTNTLASENYHDADSDKKTAYTQAVTNA
                     ENILNKNSGSNLDKVAVENALSQVTNAKGALNGNHNLEQAKSNANTTINGLQHLTTAQ
                     KDKLKQQVQQAQNVAGVDTVKSSANTLNGAMGTLRNSIQDNTGTKNGQNYLDATESNK
                     TNYNNAVDRANGVINATSNPNMDANAINQIATQVTSTKNALDGTHNLTQAKQTATNAI
                     DGATNLNKAQKDALKAQVTSAQRVANVTSIQQTANELNTAMGQLQHGIDDENATKQTQ
                     KYRDAEQNKKTAYDQAVAAAKAILNKQTGSNSDKAAVDHALQQVTSTKDALNGDAKLA
                     EAKAAAKQNLGTLNHITNAQRTALEGQINQATTVDGVNTVKTNANTLDGAMNSLQGSI
                     NDKDATLRNQNYLDADESKRNAYTQAVTAAEGILNKQTGGNTSKADVDNALNAVTRAK
                     AALNGADNLRNAKTSATNTINGLPHLTQLQKDNLKHQVEQAQNVAGVNGVKDKGNTLN
                     TAMGALRTSIQNDNTTKTSQNYLDASDSNKNNYNTAVNNANGVINATNNPNMDANAIN
                     GMANQVNTTKAALNGAQNLAQAKTNATNTINNAHDLNQKQKDALKTQVNNAQRVSDAN
                     NVQRTATELNSAMTALKAAIADKERTKASGNYVNADQEKRQAYDSKVTNAENIISGTP
                     NATLTVNDVNSAASQVNAAKTALNGDNNLRVAKEHANNTIDGLAQLNNAQKAKLKEQV
                     QSATTLDGVQTVKNSSQTLNTAMKGLRDSIANEATIKAGQNYTDASPNNRNEYDSAVT
                     AAKAIINQTSNPTMEPNTITQATSQVTTKEHALNGAQNLAQAKTTAKNNLNNLTSINN
                     AQKDALTRSIDGATTVAGVNQETAKATELNNAMHSLQNGINDETQTKQTQKYLDAEPS
                     KKSAYDQAVNAAKAILTKASGQNVDKAAVEQALQNVNSTKTALNGDAKLNEAKAAAKQ
                     TLGTLTHINNAQRTALDNEITQATNVEGVNTVKAKAQQLDGAMGQLETSIRDKDTTLQ
                     SQNYQDADDAKRTAYSQAVNAAATILNKTAGGNTPKADVERAMQAVTQANTALNGIQN
                     LERAKQAANTAITNASDLNTKQKEALKAQVTSAGRVSAANGVEHTATELNTAMTALKR
                     AIADKAETKASGNYVNVDANKRQAYDEKVTAAENIVSGTPTPTLTPSDVTNAATQVTN
                     AKTQLNGNHNLEVAKQNANTAIDGLTSLNGPQKAKLKEQVGQATTLPNVQTVRDNAQT
                     LNTAMKGLRESIANEATIKADQNYTDASQSKQTDYNNAVTAAKAIIGQTTSPTMNAQE
                     INQAKDQVTAKQQALNGQENLRTAQTNAKQHLNGLSDLTNAQKEAAKRQIEGATHVNE
                     VTQAQNNADALNTAMTNLKNGIQDQNTIKRGVNFTDADEAKRNAYTNAVTQAEQILNK
                     AQGPNTAKDGVETALQNVQRAKNDLNGNQNVANAKTTAKNALNNLTSINNAQKEALKS
                     QIEGATTVAGVNQVSTTASELNTAMSNLQRGINDEAATKAAQKYTDADREKQTAYNDA
                     VTAAKTLLNKTAGSNDNKAAVEQALQRVNTAKNALNGDARLNEAKKTAKQQLATMSHL
                     TDAQKANLTSQIERGTTVAGVQGIQANAGTLNQAMNQLRQSIASKDATKSSEDYQDAN
                     TDLQNAYNRAVSDAEGIISATNNPEMNPDTINQKASQVNSAKSALNGDEKLAAAKQTA
                     KTDIGRLTDLNNAQRTAANAEVDQAPNLAAVTAAKNKATSLNTAMGNLKHALAEKDNT
                     KRSVNYTDADRPKQQAYDTAVTQAEAITNANGSNANETQVQAALNQLNQAKNDLNGDN
                     KVAQAKEAAKRALASYNNLNNAQSTAATSQIDNATTVAGVTAAQNTANELNTAMGQLQ
                     NSINDQNTVKQQVNFTDADQGKKDAYTNAVTNAQGILDKAHGQNMTKAQVEAALNQVT
                     TAKNALNGDANVRQAKSDAKANLGTLTHLNNAQKQDLTSQIEGATTVNGVNGVKTKAQ
                     DLDGAMQRLESAIANKDQTRASENYIDADPTKKTAFDNAITQAESYLNKDHGANKDKQ
                     AVEQAIQSVTTAKNALNGDANLQRAKTEATQAIDNLTHLNTPQKTALKQQVNAAQRVS
                     GVTDLKNSATSLNNAMDQLKQAIADHDTIVAGGNYTNASPDKQGAYTDAYNAAKNIVN
                     GSPNVVTNAADVTAATQRVNNAETGLNGDSNLATAKQQAKDALRQMTHLSAAQKQSIT
                     GQIDSATQVTGVQSVKDNATNLDNAMNQLRNSIANKDEVKASQPYVDADTDKQNAYNT
                     AVTSAENIINATSQPTLDPSAVTQAANQVNTNKTALNGVQNLANKKQETTANINQLSH
                     LNNAQKQDLNTQVTNAPNISTVNQVKTKAEQLDQAMERLINGIQDKDQVKQSVNFTDA
                     DPEKQTAYNNAVTAAENIINQANGTNANQSQVEAALSTVTTTKQALNGNRKVTDAKNN
                     ANQTLSTLDNLNNAQKGAVTGNINQAHTVAEVTQAIQTAQELNTAMGNLKNSLNDKDT
                     TLGSQNFADADPEKKNAYNEAVHNAENILNKSTGTNVPKDQVEAAMNQVNTTKAALNG
                     TQNLEKAKQHANTAIDGLSHLTNAQKDALKQLVQQSTTVAEAQGNEQKANNVDAAMDK
                     LRQSIADNATTKQNQNYTDASPNKKDAYNNAVTTAQGIIDQTTSPTLDPTVINQAAGQ
                     VSTTKNALNGNENLEAAKQQATQSLGSLDNLNNAQKQTVTDQINGAHTVDEANQIKQN
                     AQNLNTAMGNLKQAIADKDATKATVNFTDADQAKQQAYNTAVTNAENIISKANGGNAT
                     QTEVEQAIQQVNAAKQALNGNANVQHAKDEATALINSSNDLNQAQKDALKQQVQNATT
                     VAGVNNVKQTAQELNNAMTQLKQGIADKEQTKADGNFVNADPDKQNAYNQAVAKAEAL
                     ISGTPDVVVTPSEITAALNKVTQAKNDLNGNTNLATAKQNVQQAIDQLPNLNQAQRDE
                     YNKQITQATLVPNVNAIQQAATTLNDAMTQLKQGIANKAQIKGSENYHDADTDKQTAY
                     DNAVTKAEELLKQTTNPTMDPNTIQQALTKVNDTNQALNGNQKLADAKQAAKTNLGTL
                     DHLNDAQKQALTTQVEQAPDIATVNNVKQNAQNLNNAMTNLNNALQDKTETLNSINFT
                     DADQAKKDAYTNAVAHAEGILSKANGSNASQTEVEQAIQRVNEAKQALNGNDNVQRAK
                     DAAKQVITNANDLNQAQKDALKQQVDAAQTVANVNTIKQTAQDLNQAMTQLKQGIADK
                     DQTKANGNFVNADTDKQNAYNNAVAHAEQIISGTPNANVDPQQVAQALQQVTQAKGDL
                     NGNHNLQVAKDNANTAIDQLPNLNQPQKTALKDQVSHAELVTGVNAIKQNADALNNAM
                     GTLKQQIQANSQVPQSVDFTQADQDKQQAYNNAANQAQQIANGTPTPVLSPDTVTQAV
                     TTMNQAKDALNGDEKLAQAKQDALANLDTLRDLNQPQRDALRNQINQAQALATVEQTK
                     QNAQNVNATMGNLKQGIANKDTVKASENYHDADADKQTAYTNAVSQAEGIINQTTNPT
                     LNPDEITRALTQVTDAKNGLNGEAKLATEKQNAKDAVSGMTHLNDAQKQALKGQIDQS
                     PEIATVNQVKQTATSLDHAMDQLSQAINDKAQTLADGNYLNADPDKQNAYKQAVAKAE
                     ALLNKQSGTNEVQAQVESITNEVKTAKQALNGNDNLANAKQQAKQQLANLTHLNDAQK
                     QSFENQITQAPLVTDVTTINQKAQTLDHAMELLRNSIADNQATLASEDYHDATAQRQN
                     DYNQAVTAANNIINQTTSPTMNPDDVNRATTQVNNTKVALDGDENLVAAKQQANNRLD
                     QLDHLNNAQKQQLQSQITQSSDIAAVNGHKQTAESLNTAMGNLINAIADHQAVEQRGN
                     FINADTDKQTAYTTAVNEAEAMINKQTGQNANQTEVEQAITKVQTTLQALNGDHNLQV
                     AKTNATQAIDALTSLNDPQKTALKDQVTAATLVTAVHQIEQTANTLNQAMHGLRESIQ
                     DNATTQANSKYINEDQPEQQNYDQAVQAANNIINEQTATLDNNAINQAATTVNTTKAA
                     LHGDVKLQNDKDRAKQTVSQLAHLNNAQKHMEDTLIDSETTRSAVNHDLTEAQALDQL
                     MDTLQQSIADKDATRASSAYVNAEPNKKQAYDEAVQNAESIIAGLTNPTINKGNVSSA
                     TQAVTSSKNALDGVERLAQDKQTAGNSLNHLDQLTPAQQQALENQINNATTRDKVAEI
                     IAQAQALNEAMKALKESIKDQPQTEASSKFINEDQAQKDAYTQAVQHAKDLINKTTDP
                     TLAKSIIDQATQAVTDAKNNLHGDQKLAQDKQRATETLNNLSNLNTPQRQALENQINN
                     AATRDKVAQKLTEAQALNQAMEALRNSIQDQQQTEAGSKFINEDKPQKDAYQAAVQHA
                     KDLINQTSNPTLDKAQVEQLTQAVNQAKDNLHGDQKLADDKQHAVTDLNQLNGLNNPQ
                     RQALESQINNAATRGEVAQKLTEAQALNQAMEALRNSIQDQQQTESGSKFINEDKPQK
                     DAYQAAVQNAKDLINQTGNPTLDKSQVEQLTQAVTTAKDNLHGDQKLARDQQQAVTTV
                     NALPNLNHAQQQALTDAINAAPTRTEVAQHVQTATELDHAMETLKNKVDQVKTDKAQP
                     NYTEASTDKKEAVDQALQAAQSITEPNNGSNANKDAVEQALTKLQEKENELNGNERVA
                     EAKTQAKQTVDQLTHLNADQIATAKQNIDQAMKLQPIAELVDQATQLNKSMDQLQQAV
                     NDHTNVEQTVDYTQADSDKQNAYKQAIADAENVLKQNANKEQVDQALQNILNAKQALN
                     GDERVALAKTNGKHDIDQLNTLNNAQQDGFKGRIDQSNDLNKQIVDEAKALNRAMNQL
                     SQEITGNEGRTKGSTNYVNADTQVKRVYDDAVDKAKEALNKATGQNLTAEEVIKLNDA
                     VTAAKQALNGEERLNKRKSEALQRLDQLTHLNNAQRQLATQQINNAETLNKASRAINR
                     AVQLDDAMGAVQQYIDDHHFDVISSTNYINADDNLKANYDNAITNAAHELDKVQGSAI
                     TKAEAEQLKQNIIDAQQALNGDQNLATAKDKANAFVDTLNGLNQQQQDLAHQAINNAD
                     TVTGIANIINDQIDLNNAMETLKHLVDNEIPTAEQTINYQNADDVAKSIFDDAKRLAN
                     TLLNSDNTNVNDINGAIQAVNDAIQNLNGDQRLQEAKDKAIQNVNKVLADKLKEIEAS
                     NATDQDKLIAKNKAEELANSIINNINKATSNQDVSQVQTAGNHAIEQVHANEIPKAKI
                     DANKDADKQVQALIDEIDRNPNLTDKEKQALKDRINQILQQGHNGINNAMTKEEIEQA
                     KAQLAQALQEIKDLVKAKENAKNAIKALANAKRDQINSNPDLTPEQKAKALKEIDEAE
                     KRALENIENAQTKDQLNQGLNLGLDDIRNTHVWEVDTQPAVNEIFDATPEQILVNGEL
                     IVHRDDIITEQDILAHINLVDQLTAEVIDTPSTATISDSLTAKVEVTLLDGSKVIVNV
                     PVKVVEKELAVVKQQAIESIENAAQQKINDINNHTTLTPEQKEAAIAEVNKLKQQAIE
                     QINNATDVHSVEEVQQQEQTHIEQFNPEQFTIDQAKSNAIKSITDAIQHMIDEINASK
                     DLTDKEKQEAISKLNQLKEQAIQAIQRAQSIDEITQQLEQFKAQIKAANPFAKELEKR
                     KKVAISKIKDISTDAIERIKNSSTGTAEERQAAMNRINEIVLETIRDINNAQTPQQVE
                     AALNNGIARILAVQIVTSNNSK"
BASE COUNT        14462 a         6372 c         6605 g         8852 t
ORIGIN      
        1 atatgaataa ttaattaatg gtatttacat atgcataccc acaagataaa atgattgtga
       61 aataattcac aaaatcaaaa ggagtgttgc aaatgttagt tgcagtagtc aaagaattaa
      121 aacaaggtga aggacgtgta gcttgcacac ccgaaaatgt gcgtaagtta acggatgcag
      181 gacataaagt aattgtagaa aaaaatgctg gcattggttc aggattttct gacgatatgt
      241 atgaaaaaga aggcgctaag attgtaactc acgaacaagc atgggaagca gatctggtta
      301 tcaaagtaaa agaaccacat acaagtgaat atcaatattt taaaaaagat caaatcatct
      361 ggggattctt acatttagca tcttcaaagg aaatagtaga aaaaatgcaa gaagttggtg
      421 ttactgctat tagtggtgaa accattataa aaaatggaaa agcagaatta ttagcgccaa
      481 tgagtgctat agcaggtcaa cgctcagcaa ttatgggagc ttactactct gaagcacaac
      541 atggtggtca aggtacttta gtgactggtg tacatgaaaa tgtggatata cctggtagta
      601 catatgtgat tttcggtggt ggcgtagcag caacaaatgc agcaaatgtt gccttgggac
      661 taaatgctaa agtaatcatt atcgagttaa acgatgatcg cattaaatat ttacaagaca
      721 tgtatgcaga aaaagatgtc acagtagtca aatcaacacc agaaaattta gcagaacaaa
      781 taaaaaaagc agatgtattt atttctacaa ttttaattcc aggtgcgaaa ccgccaaaat
      841 tggttactcg tgagatggtt aaatcaatga aaaaaggttc agtattaatc gatatagcta
      901 ttgaccaagg tggaactatt gaaacaatta gaccaactac aatttctgat ccagtgtatg
      961 aagaagaagg tgtgattcat tacggtgtac caaaccaacc aggagcagtc ccaagaactt
     1021 caacaatggc attagcacaa ggaaatattg attatatatt agaaatttgt gacaaaggct
     1081 tagaacaagc aattaaagat aatgaagcct taagtactgg tgtaaacatt taccaaggac
     1141 aagtgacaaa tcaaggatta gctacatcac atgacctaga ttataaagaa atattaaatg
     1201 ttatcgaata gatagtaatt taaatgaaat tgagtgaaat gaatatttta aatatagcat
     1261 tatagtttgg actaaaaatt tacaaaacgg aaggatgtaa ttattatgac aaccaacaca
     1321 gttacattac aaacagcaca tattgtaagt ttaggagata tcgaagaagc taaagcaagc
     1381 attaaaccat ttattcgtcg aacacctcta attaaatcaa tgtatttaag ccaaagtata
     1441 actaaaggga atgtatttct aaaattagaa aatatgcaat tcacaggatc ttttaaattt
     1501 agaggcgcta gcaataaaat taatcactta acagatgaac aaaaagaaaa aggcattatc
     1561 gcagcatctg ctgggaacca tgcacaaggt gttgctttaa cagctaaatt attaggcatt
     1621 gatgcaacta tcgtaatgcc tgaaacagca ccacaagcaa aacaacaagc aacaaaaggc
     1681 tatggggcaa aggttatttt aaaaggtaaa aactttaacg aaactagact ttatatggaa
     1741 gaattagcga aagaaaatgg catgacaatc gttcatccat atgacgataa gtttgtaatg
     1801 gcaggccaag gaacaattgg tttagaaatt ttagatgata tttggaatgt gaatacagtc
     1861 atcgtaccag ttggcggtgg aggattaatt gcaggtattg ccaccgcatt aaaatcattt
     1921 aacccttcaa ttcatattat cggtgttcaa tctgagaatg ttcatggtat ggctgagtct
     1981 ttctataaga gagatttaac tgaacatcga gtggatagca caatagcaga tggttgtgat
     2041 gtaaaagttc ctggtgaaca aacatatgaa gtagttaaac atttagtaga tgaatttatt
     2101 cttgttactg aagaagaaat tgaacatgct atgaaagatt taatgcagcg tgccaaaatt
     2161 attactgaag gtgcaggcgc attaccaaca gctgcaattt taagtggaaa aataaacaat
     2221 aaatggcttg aagataaaaa tgttgttgca ttagtttcag gcgggaatgt tgacttaact
     2281 agagtttcag gtgtcattga acatggactg aatattgcag atacaagcaa gggtgtggta
     2341 ggttaaaaca tttaatctta aaaatgaggt gtaattatgt caaatggtaa agaattacaa
     2401 aaaaatatag gtttcttctc agcgtttgct attgttatgg ggacagttat tggttcagga
     2461 gtattcttta aaatatcaaa cgtaacagaa gtaacaggaa cagcaggaat ggccttgttt
     2521 gtatggttcc taggcggcat cattaccatt tgtgcggggt taacagcagc agaacttgct
     2581 gctgcaatcc ctgaaacagg tggcttaacg aagtatatag aatatacata cggtgatttc
     2641 tggggcttct tatcaggctg ggcacaatca tttatttatt ttccagcaaa cgtagcagca
     2701 ttgtctatcg tatttgcgac acagttaatt aatttattcc atttatctat aggttcatta
     2761 ataccaatag caatcgcatc tgcgttatct attgtgttga taaatttcct aggttcaaaa
     2821 gcaggtggaa ttttacaatc agttacatta gtaattaaac tgattccaat catcgttatc
     2881 gtaatttttg gtatttttca atctggagat atcacttttt cattaattcc aactacaggt
     2941 aattcaggaa atggtttctt tacagcaatt ggtagtggtt tattagcaac tatgtttgca
     3001 tatgatggtt ggattcatgt aggaaatgtt gcgggggaac ttaaaaatcc taaacgcgat
     3061 ttacctttag cgatttcagt tggtatcggt tgtattatgg ctgtgtattt attaattaac
     3121 gctacattct tattaacgtt gccaattgaa ctacttgctg gtaatttaaa tgcagcttca
     3181 gatacatcaa aaatattatt tggtgaaaat ggcggtaaga ttattacaat tggtatatta
     3241 atttctgttt atggtacgat caatggctat actatgactg gtatgcgcgt accatatgca
     3301 atggctgaaa gaaaattatt gccatttagc cacttattcg caaaattaac aaaatctggc
     3361 gcaccatggt ttggcgcaat tatacaactt ataatcgcta tcatcatgat gtcaatggga
     3421 gcatttgata caattacaaa catgttaatc tttgttattt ggttgttcta ttgtatgtca
     3481 tttgttgcgg taataatttt aagaaaacgt gaaccaaata tggagcgacc atataaagta
     3541 ccgttatatc caatcatacc tttaattgct attttggcag gatcatttgt attaattaat
     3601 acactgttta cacaatttat actagcaatt attgggattc taatcacagc acttggtata
     3661 ccagtttatt actataagaa gaaacaaaaa gcagcataag gtaagataac tagcattgag
     3721 aataaatgga tggactacta ataaatttaa agttttacac attaaaatca aaaaccattc
     3781 aattattcta tcgaacagac aaatttctgt tatggaattt gtctgttttc aaaagtatag
     3841 ggaggcaaat agagatggaa aagccgtcaa gagaggcatt tgaaggcaat aataagttgt
     3901 taataggaat tgttttaagt gtaataacgt tttggctatt tgcacaatca ttggttaatg
     3961 ttgtaccaat acttgaagat agtttcaata cagatattgg aacggtaaat atcgccgtta
     4021 gtataactgc tttattttca ggaatgtttg tagtaggagc aggtggtctt gctgataaat
     4081 atggcagaat taaactcacg aacattggta ttatcttaaa tatattgggt tcattattaa
     4141 tcattatttc aaatattcct ttattactta ttttaggaag attaattcaa ggactttcag
     4201 cagcatgtat tatgcctgca actttgtcta ttattaagtc atattacatt gggaaagata
     4261 gacaacgcgc tttaagttat tggtcaattg gctcatgggg cggctcaggt gtttgttcat
     4321 tttttggagg tgcagttgca acgcttttag gttggcgttg gattttcatc ctatcaatta
     4381 taatttcatt aattgcgcta tttcttatta aaggcacacc tgaaactaaa tctaaatcga
     4441 tttctctaaa taaatttgac attaaaggtc tggttctttt agtcattatg ctcctcagtt
     4501 taaacatttt aattactaaa ggatcagaat taggtgtaac ctcacttctt tttatcactt
     4561 tattagcaat tgcaattgga tcttttagtt tatttatagt tcttgaaaag cgtgctacaa
     4621 atcctttaat cgattttaaa ttatttaaaa ataaagctta tacaggtgca acagcttcaa
     4681 actttttgtt aaatggtgtt gcgggaacat taatagtagc caacacattt gttcaaagag
     4741 gtttaggata ttcttcattg caagcaggaa gtttatcaat cacttattta gtaatggtac
     4801 taattatgat tcgtgttggt gaaaagttac ttcaaacact cggatgcaag aaaccaatgt
     4861 taattggaac aggagttctt attgtcggag aatgtctcat ttcattaaca tttttgccag
     4921 aaatattgta tgtcatttgt tgtgttatag gttatttatt ctttggttta ggactaggaa
     4981 tatatgctac accatcaaca gatacagcaa ttgcaaatgc accgttagaa aaagtaggcg
     5041 ttgctgcagg tatctataaa atggcttctg cattaggtgg agcatttggc gtcgcattaa
     5101 gtggtgcagt ttatgcaatc gtatcaaata tgacaaacat ttatacaggt gcaatgattg
     5161 cattatggtt aaacgcaggt atgggaattt tatcattcgt tatcattttg ttacttgtgc
     5221 ctaaacaaaa cgacactcaa ttatgataat tgagaattaa attgaaatca tataagtcgc
     5281 tacaatatta aacaaaaata taaaccgatt cttatgtgtc attattttaa atgaacatag
     5341 ggattggttt tttattactc ttttacgcta ctttatttat aattattata aattgtcaca
     5401 aattcaattt accttacaat atattttttg ttattatatt ctggagcata aataaattgt
     5461 tcaacacata gttgtaatgt gtttcaatac tttttggata gattgcgaaa ttgtattgaa
     5521 tcgtcatcgt tttaaatttt taaatgagaa tggaatgagc attacaatac acaagcaatc
     5581 aaaagtaaat acattcacaa cacaacagag acataacaac aagataagga gtgaacaata
     5641 gctgtgaatt atcgtgataa aattcaaaag tttagtattc gtaaatatac cgttggtaca
     5701 ttttcaacgg tcattgcgac attggtattt ttaggattca atacatcaca agcacatgct
     5761 gctgaaacaa atcaaccagc aagcgtggtt aaacagaaac aacaaagtaa taatgaacag
     5821 actgagaatc gagaatctca agtacaaaat tctcaaaatt cacaaaatgg tcaatcatta
     5881 tctgctactc atgaaaatga gcaaccaaat attaatcaaa caaaccatgt agatgtaagt
     5941 gcagaacaat catctacaac tgaaaatgaa caagcagtat ctcaaaataa gcaaacaaag
     6001 aaagatacag cagatgctac gccaacacaa tcggctaaag cggaaagcaa gcatgaacaa
     6061 aatgaaagtc gttctgctaa caaaaaagaa aacgacaata aagcggctca tgtagaaaat
     6121 catgaagcaa atgtagtcac agcttcagat tcacctgata atggtaacgt acaacatgac
     6181 cgaaatgaac tacaagcatt ttttgatgca aattatcatg attatcgctt tattgaccgc
     6241 gaaaatgcag attctgggac atttaactat gtaaaaggca tttttgacaa gattaatacg
     6301 ttattaggaa gcaatgatcc aataaacaat aaagacttgc aacttgcata taaagaattg
     6361 gaacaagctg ttgcattgat ccgcactatg cctcaacgtc aacaaactag ccgacgctca
     6421 agcagaattc aaacgcgttc agttgagtca agagctgcag aacctagatc agtatcaagt
     6481 tatcaaaatg cagactcttc atactacgtt gaaaatgcta atgacggttc agggtatcct
     6541 gtaggtacat atattaatgc atcaaacaaa ggtgcgccat tctatcttcc tacagcccca
     6601 tggaatactt tgaaagcatc agctgcaaaa gaaatagtac tgatcacagc gaaacaaact
     6661 ggagacggat atcaatgggt aattaagttt aacaaaggtc atgcaccaca tgaaaatatg
     6721 attttctggt ttgctttacc gtcagatcaa gtgccagttg gacgtactga ctttgtaaca
     6781 gtgaatgcag acgggacgaa tgtacaatgg agtaatggtg cgggagctgg tgcttacaaa
     6841 ccacttccac aaatgtggcc atatggtgta aatgactcac gttcgcgaga ctttaaaatt
     6901 agaaatagaa gcggacaagt tatttatgat tggactgatg ttcatgtaaa tacattgaga
     6961 gacttagcgc gagcaggaga ttatttcagt gaagctggag cacccgctgc gactaaagct
     7021 ataggggaac aaacgtttag atatattaat ggtgaaagac caacagaatc ccctggtgca
     7081 tcaaaagttt atacttttat tggtgctggc gatgcaagtt atacgatttc atttaaaaca
     7141 caaggaccaa caacgaacaa attgtattat gcagccggtg gtcgtgctct agaatacaat
     7201 caattattta tgtatagcca actatacgta gaatcaacgc aagaccacca acaacgactt
     7261 gatggtttta gacaagtagt taatcgttct tatcgtttag gtacaacaaa aagagtagaa
     7321 gtaagtcagg gtaacattca aactaaaaaa gtacttgaaa gtacaaacct aaatatcgat
     7381 gactttatgg atgatccatt aagttatgtt aagacaccga gtaataaagt gttaggtttt
     7441 tatccaacaa atgcgaatcc caatgcatat agacatggtg gaactaatcc attaaatgaa
     7501 tatcaattaa gtcagttatt tactgatgat aaactacaac aggcagctag aactggcaat
     7561 ccaatacgat taatgattgg atttgactat ccagatggtc atggcaacgc agaaacttta
     7621 gtaccagtta acttgacggt attacctgaa attcaacata atattaaatt ttataaaaat
     7681 gatgacacac aaaatattgc cgataaacca gcttcaagac aagcaggaca tccaatcttc
     7741 tatgtatatg caggtaatca agggaatgct tcagtgaatt taggtggaag cgtaacatct
     7801 attcaaccgt tacgtattaa tttaacaagt agtgaaaatt ttacagatag agattggcaa
     7861 ataacaggta ttccacgtac gttacacatt gaaaactcga caaatagacc taataatgcc
     7921 agagaacgta acattgaatt ggttggtaat ttattaccgg gtgactattt tggaacaata
     7981 cgttttggcc gtaaagaaca attattcgaa atacgtgtta agccacatac accaacaatt
     8041 actacaactg ctgaacaact aagaggtaca gcattacaaa aagtgccaat tacagttacg
     8101 aatattccgt tggacccatc gtcattagtt tatatcgttt atccaacaga tcaaacaaga
     8161 gatggtggat ctgaagcaga ccaaatgcct tcaaactatt caatactggc gactggtaca
     8221 cctgatggtg tgcataatac cataacaata caaccaaaag actatactgt gtttattcct
     8281 ccggtaggta aacaaattag agcattgatt tattacaata aagttgttgc ttctaatatg
     8341 agtaatgcgg ttactatttt gccggatgat attccgccga caattaataa tccagttggc
     8401 ttaaatgcaa agtattatcg tggtgatgaa gtcaacttta caatgggagt ttcagataga
     8461 cattctggaa taaaaaatac aactattact actttaccga atggttggac atcaaattta
     8521 actaaagcgg ataagaataa tggctcatta tctattactg gtagagtgag tatgaatcag
     8581 gcatttaaca gtgatattac atttaaagtg tcagcgacag ataatgtcaa taatacgaca
     8641 aatgatagtc aatctaaaca tgtgacagta catgtaggta aaattagtga agatgcgcat
     8701 ccaattgtat tagcaaattc tgaaaaagtt gtcgttgtaa atccgacatc tgtatctaat
     8761 gatgaaaaac aacgaataat tactgcattt atgaataaaa accaaaatat aagaggttat
     8821 ttagcttcat caaatccagt tacagttgat aataatggta atgtcacatt acattaccgt
     8881 gatggctcat caacaacgct tgatgctaca aatgtgatga catacgaacc agttgtgaaa
     8941 cctgaatatc aaactgccaa tgcacctaaa acggcaacgg taacaattgc taaaggacaa
     9001 tcatttagta taggtgatat taaacaatat ttcactttaa gtaatggaca agcgattcca
     9061 aatggaacat ttacaaatat tacttcggac agaacgattc caacagcaca agaagttagt
     9121 caaatgaatg caggtacaca gttataccat atcgtcgctt caaacgcgta tcataaagac
     9181 actgaagact tatatattag tttgaaaatc atcgatgtga aacaaccaga gggtgatcaa
     9241 cgtgtatatc gtacatcaac atatgattta actactgatg aaatttcaaa agtaaaacaa
     9301 gcatttatta atgccaatag ggatgcgatt acgtttgcag aaggagatat atcggttaca
     9361 aatacaccaa atggtgccaa tgtgagtacc gttactgtca atattaataa aggtcgatta
     9421 acgaaatcgt ttacatcaaa ccttgctaat atgaatttct tacgttgggt taatttccca
     9481 caagattata ctgtatcttg gacaaatgcg aaaatcgcta gtagaccaac tgatggtggt
     9541 ttatcatggt ctgatgatca taaatcatta atttatcgct atgatgcaac attaggtaca
     9601 ccaattacga cgaatgatat tttaacgatg ttaaaagcaa caacgacagt gcctggattg
     9661 cgtaataaca ttgccggtaa tgagaaaact caagctgaag ctggtggcag accaaactat
     9721 agaccaactg gatattcaca agcaaatgct tcatcagatg ggcaacgtca atatacgtta
     9781 aatggacaag taatccaagt tctagatatt attaacccga cgaatggttt cggtggtcaa
     9841 acgattacaa actcaaatgt tcgtgcaaac catagtaatt caactgttgt tagtgtcaat
     9901 gaaccggcag ctaatggtgc gggtgcattt acaattgatc atgtggtaaa aaataatact
     9961 acgcataatg cagctgatgc ggtatacaaa gcgcagttat acttatctcc atatggacca
    10021 aaacaatatg ttgaacattt aaatcaaaat acgggaaata ctaccgatgc tattaacatt
    10081 tattttgtac ctagtgatct agtaaatcca actatttcag taggtaatta cgcaaatcat
    10141 caagtattct ctggtgaaac atttaccaat acgattacag cgaatgataa ctttggtgtg
    10201 caatctgtaa ctgtaccaaa tacatcacaa attacaggta ctgttgacaa taatcatcag
    10261 cacgtttctg caacagcgcc aaatgtgaca tctgctacaa ataaaacgat caatttagtg
    10321 gcaactgata caagcggcaa tactgcaaca acgtcataca atgtcacaat taaaccttta
    10381 cgtgataaat atcgagttgg aacatcatca acggctgcta atccagtgag aattgctaat
    10441 atttcgaata atgcgatagt atcacaagct gatcaaacag caattattaa ttcattgacg
    10501 tttactgaaa cagtaccaaa tagaagttat gcaagagcaa gtgcaaatga aatcactagt
    10561 aaaacagtta gtaatgtgag tcgtactgga aataatgcca atgtcacagt aactgttact
    10621 tatcaagatg gaacaacatc aacagtgact gtacctgtaa agcatgtcat tccagaaatc
    10681 gttgcacatt cgcattacac tgtacaaggc caagacttcc cagcaggtaa tggttctagt
    10741 gcatcagatt actttaagtt atctaatggt agtgccattc cagatgcaac tattacatgg
    10801 gtaagtggac aagcgccaaa taaagataat acgcgtattg gtgaagatat aacagtaact
    10861 gcacatatct taattgatgg cgaaacaacg ccgattacga aaacagcaac atataaagta
    10921 gtaagaactg taccgaaaca tgtctttgaa actgacagag gtgttttata cccaggtgtt
    10981 tcagatatgt atgatgcaaa acaatatgtt aagccagtga ataattcttg gtcgacaaat
    11041 gcgcaaaata tgaatttcca atttgtggga acttatggac ctaacaaaga tgttgtaggt
    11101 atatcaacgc gtcttattag aatcacatat gataatagac aaactgaaga attaactatt
    11161 ttatctaaag ttaaaccaga cccaccgaga attgatggca actctgtaac atataaagca
    11221 ggtcttacaa accaagaagt taaagttaat aacgtattaa gtaactcgac ggttaaattg
    11281 tttaaagctg acaatacgcc attaaatgtt acaaatatta tccatggcag tggctatagt
    11341 tcggttgtga cagtaagtga tgcgttacca aatggtggaa ttaaagcgaa atcttcaatt
    11401 tcaatgaaca atgtgacgta tacgacgcaa gacgaacatg gtcaagttgt tacagtaaca
    11461 agaaatgaat ctgttgattc aaatgatagt gcttctgtta cagtaacacc acaattacaa
    11521 gcaactactg aaggcgctgt atttattaaa ggtggcgacg gttttgattt cggacacgta
    11581 gaaagattta ttcaaaaccc accacatggc gcaacggtcg catggcacga taatccagat
    11641 acatggaaga atacagtcgg taacactcat aaaactgcgg ttgtaacatt accaagtggt
    11701 caaggtacgc gtaatgttga agttccagtc aaagtttatc cagttgctaa tgctaaggcg
    11761 ctatcacgtg atgtgaaagg tcaaaatttg actaatggaa cggatgcgat gagctacatt
    11821 acatttgatc caaatacaaa cacaaatggt atcactgcag catgggcaaa tagacaacaa
    11881 ccaaataacc aacaagcagg cgttcaacat ttaaatgtcg atgtcacata tccgggtatt
    11941 tcagctgcta aacgagttcc tgtaactgtg aacgtatatc aatttgaatt ccctcaaact
    12001 acttatacaa caacagttgg tggcacttta gcaagtggta cgcaagcatc gggatatgca
    12061 catatgcaaa acgctactgg tttaccaact gatggattta cgtataaatg gaataatgca
    12121 gcaacgggta caaacgatgc aaactgggca gcaatgaata aaccgaatgc ggctaaagtc
    12181 gttaatgcga aatatgatgt tatctataat ggacatacat ttgcaacatc tctaccagcg
    12241 aagtttgtag taaaagatgt acaaccagcg aaaccaactg tgactgaaac agcggcagga
    12301 gcgattacaa ttgcacctgg agcaaaccaa acagtgaata cacatgccgg taacgtaaca
    12361 acatacgctg ataaattagt tattaaacgt aacggcagtg ttgtgacgac atttacacgt
    12421 cataataata cgagtccatg ggttaaagaa gcatcagcaa ctaatgtaac aggtattgtt
    12481 ggaacgaata atggtattac tgttgcagca ggtactttca atcctgctga tacaattcaa
    12541 gttgttgcaa cacaaggtag tggtgaaaca atcagtgacg aacaacgtag tgatgatttc
    12601 acagttgtcg cacctcaacc gaaccaagcg actactaaga tttggcaaaa tggtcatatt
    12661 gatatcacgc ctaataatcc atcagggcat ttaattaatc caactcaagc aatggatatt
    12721 gcttacactg aaaaagtggg taatggtgca gaacatagta agacaattaa tgttgttcgt
    12781 ggtcaaaata atcaatggac aattgcgaat aagcctgact atgtaacgtt agatgcacaa
    12841 actggtaaag tgacattcaa tgccaatact atcaagccaa attcagcaat taccattaca
    12901 ccgaaagcag gtacaggtca ctcagcaagc agtaatccaa gtacattaac tgcaccggca
    12961 gcacatactg tcaacacaac agaaattgtg aaagattatg gttcaaatgt aacagcatct
    13021 gaaattaaca atgcagttca agttgctaat aaacgtactg caacgattaa aaatggcaca
    13081 gcaatgccta ctaatttagc tggtggtagc acaacgacga ttcctgtgac agtaacatac
    13141 aatgatggca gtactgaaga agtacaagag tccattttca caaaagcgga taaacgtgag
    13201 ttaatcacag ctaaaaatca tttagatgat ccagtgagta cagatggtaa aaagccaggt
    13261 acaattacgc agtacaataa tgcaatgcat aatgcgcaac aacaaatcaa tgctgcgaaa
    13321 acagaagcgc aacaagtgat taataatgag cgtgcaacac cacaacaagt gaacgcagca
    13381 ttatctaaag tccaagcagc acaaactaag ataaatgaag ctaaagcttt acttcaaaat
    13441 aaagaagata atagccaatt agtaacgtct aaaaataact tacaaagttc tgtgaaccaa
    13501 gtaccatcaa ctgcgggtat gacgcaacaa agtattgata actataatgc gaagaaacgt
    13561 gaagcagaat cggaaattac agctgcacaa cgtatcattg acaatggaga tgcaactgca
    13621 caacaaattt cagatgaaaa acatcgtgtc gataacgcat taacagcatt aaaccaagcg
    13681 aaacatgatt taactgcaga tacacatgcc ttagagcaag cagtgcaaca attgaatcgc
    13741 acaggtacaa cgactggtaa gaagccagca agtatcactg cgtataataa ttcgattcgt
    13801 gcacttcaaa gtgacttaac aagtgctaaa aatagcgcta atgctatcat tcagaagcca
    13861 ataagaacag tgcaagaggt acaatctgca ttaacaaatg taaatcgtgt caatgagcga
    13921 ttaacgcaag caattaatca attagtacct ttagctgata atagtacttt aagaactgct
    13981 aagacgaaac ttgatgaaga aattaataaa tcagtaacta ctgatggtat gacacaatca
    14041 tcaatccaag catatgaaaa tgctaaacgt gcgggtcaaa cagaatcaac aaatgcacaa
    14101 aatgttatta acaatggtga cgcgacagac caacaaattg ccgcagaaaa agctaaagta
    14161 gaagaaaaat ataatagctt aaaacaagca attgctggat taacaccaga cttggcacca
    14221 ttacaaactg caaaaacgca gttgcaaaat gatattgatc agccaacgag tacgactggt
    14281 atgacaagcg catctgttgc tacatttaat gaaaaacttt cagcagctag aactaaaatt
    14341 caagaaatta atcgcgtact ggcatctcat ccagatgttg caacgattcg tcaaaacgtg
    14401 acagcagcga atgctgctaa atcagcactt gatcaagcac gtaatggctt aacagtcgat
    14461 aaagcgcctt tagaaaatgc gaaaaatcaa ctacaacata gtattgatac gcaaacaagt
    14521 acaactggta tgacgcaaga ttctattaat gcatacaatg cgaagttaac agctgcacgt
    14581 aataagattc aacaaatcaa tcaagtatta gctggttcac cgacagttga tcaaattaat
    14641 acaaatacgt ctgcagcaaa ccaagctaaa tctgatttgg atcatgcgcg tcaagcatta
    14701 acaccagata aaacaccgct tcaaaatgcg aaaacgcaat tagaacaaag tattaatcaa
    14761 ccaacagata caacaggtat gacgaccgct tcgttaaatg cgtacaacca aaaattacaa
    14821 gcagcgcgtc aaaagttaac tgaaattaat caagtgttga atggcaaccc aactgtccaa
    14881 aatatcaatg ataaagtggc agaggcaaac caagctaagg atcaactaaa tacagcacgt
    14941 caaggtttaa cattagatag acagccagcg ttaacaacat tacatggtgc atctaactta
    15001 aaccaagcac aacaaaataa tttcacgcaa caaattaatg ctgctcaaaa tcatgctgcg
    15061 cttgaaacaa ttaagtctaa cattacggct ttaaatactg cgatgacaaa attaaaagaa
    15121 agtgttgcgg ataataattc tattaaatca ggtcaaaact acactgacgc aactcaagct
    15181 aataaacaag cgtatgataa tgcagttaat gcggctaaag gtgtcattgg ggaaacgaat
    15241 aatccaacga tggatgttaa tacagtgaac caaaaagcag catctgttaa atcgacgaaa
    15301 gatgctttag atggtcaaca aaacttacaa cgtgcgaaaa cagaagcaac aaatgcgatt
    15361 acacatgcaa gtgatttaaa ccaagcacaa aagaatgcat taacacaaca agtgaatagt
    15421 gcgcaaaatg ttcaagcagt aaataatatt aaacaaacaa ctcaaagctt aaacactgca
    15481 atgacaggtc taaaacgtgg cgttgctaat cataaccaag tcgtacaaag tgataattat
    15541 gtcaacgcag atactaataa gaaaaatgat tacaacaatg catacaacca tgcgaatgac
    15601 attattaatg gtaatccaca acatccagtt ataacaccaa gtgatgttaa caatgcttta
    15661 tcaaatgtca caagtaaaga acatgcattg aatggtgaag ctaagttaaa tactgcgaaa
    15721 caagaagcga acactgcatt aggtcaatta aataacttga ataatgcaca acgtcaaaac
    15781 ttacaatcgc aaattaatgg tgcgcatcaa atcgagacag ttaatacgat taagcaaaat
    15841 gcaactaact taaatagtgc aatgggtaat ttaagacatg ctgttgcaga taaagagcaa
    15901 gtcaaacgta cagaagatta tgcggatgca gatacagcta aacaaaatgc atataatagt
    15961 gccgtttcaa gtgctgaaac aatcattaat caatcaacaa atccgacaat gtctgttgat
    16021 gatgttaatc gtgcaacttt agctgttact actaataaaa ctgcattaaa tggtgatgaa
    16081 aaattagcac aatctaaaac agatgctgca agagcaattg atgcattacc acatttaaat
    16141 aatgcacaaa aagcagatgt taaatctaaa attaatgctg catcaaatat tgctggcgta
    16201 aatactgtta aacaacaagg tacagattta aatacagcaa tgggtaactt gcaaggtgcg
    16261 atcaatgatg aacaaacgac acttaatagt caaaattatc aagatgcgac acctagtaag
    16321 aaaacagcat acacaaatgc ggtacaagct gcgaaagata ttttaaataa atcaaatggt
    16381 caaaataaaa cgaaagatca agttactgaa gcgatgaatc aagtgaattc ggctaaaaat
    16441 aacttagatg gtacgcgttt attagatcaa gcgaagcaaa cagcgaaaca gcagttaaat
    16501 aatatgacgc atttaacaac tgcacaaaaa acgaatttaa caaaccaaat taatagtggt
    16561 actactgtcg ctggtgttca tacggttcaa tcaaatgcca atacattaga tcaagccatg
    16621 aatacgttaa gacaaagtat tgccaacaaa gatgcgacta aagcaagtga agattacgta
    16681 gatgctaata atgataagca aacagcatat aacaacgcag tagccgctgc tgaaacgatt
    16741 attaatgcaa atagtaatcc agaaatgaat ccaagtacga ttacacaaaa agcagagcaa
    16801 gtgaatagtt ctaaaacggc acttaacggt gatgaaaact tagctacggc aaaacaaaat
    16861 gcgaaaacgt acttaaacac attaacgagt attacagatg ctcaaaagaa caatttgatt
    16921 agtcaaatta gtagtgcgac aagagtgagt ggtgttgata ctgtaaaaca aaatgcgcaa
    16981 catctagacc aagctatggc tagcttacaa aatggtatta ataacgaatc tcaagttaaa
    17041 tcttctgaga aatatcgtga tgctgataca aataaacaac aagagtatga taatgctatt
    17101 actgcagcga aagcgatttt aaataaatcg acaggtccaa acactgcgca aaatgcagtt
    17161 gaagcagcat tgcaacgtgt gaatactgcg aaagatgcat tgaatggtga tgcaaaatta
    17221 attgcagctc aaaacgcagc aaaacaacat ctaggtactt taacacatat cactacagca
    17281 caacgtaatg atttaacaaa tcaaatttca caagctacaa acttagctgg tgttgaatca
    17341 gttaaacaaa gtgcaaatag tttagatggc gcaatgggta acttacaaac tgctatcaac
    17401 gataaatctg gaacattagc gagccaaaac ttcttggatg ctgatgagca aaaacgtaat
    17461 gcttacaatc aagctgtatc aaatgccgaa acaattttaa ataaacaaac tggaccgaat
    17521 acagcgaaaa ctgcagttga acaagcactt aataatgtta atagtgcgaa acatgcatta
    17581 aatggtacgc aaaacttaaa taatgcgaaa caagcagcga ttacagcaat caatggcgca
    17641 tctgatttaa atcaaaaaca aaaagatgta ttaaaagcac aagctaatgg tgctcaacgc
    17701 gtttctaatg cacaagatgt acagcgcaat gcgactgaac tgaacacggc aatgggtaca
    17761 ttaaaacatg ccatcgcaga taagacgaat acgttagcga gcagtaaata tgttaacgcc
    17821 gatagcacta aacaaaatgc atacacaact aaagttacca atgctgaaca tattattagc
    17881 ggtacgccaa cggttgttac gacaccttca gaagtaacag ctgcagctaa tcaagtaaac
    17941 agcgcgaaac aagaattaaa tggtgacgaa agattacgtg tagcaaaaca aaacgccaat
    18001 actgctattg atgcattaac gcaattaaat actcctcaaa aagctaaatt aaaagaacaa
    18061 gtgggacaag ccaatagatt ggaagacgta caaactgttc aaacaaatgg acaatcattg
    18121 aacaatgcaa tgaaaggctt aagagatagt attgctaacg aaacaacagt caaagcaagt
    18181 caaaactata cagacgcaag tccgaataac caatcaacat ataatagcgc tgtgtcaaat
    18241 gcgaaaggta tcattaatca aactaacaat ccaactatgg atactagtgc gattacccaa
    18301 gctacaacac aagtgaataa tgctaaaaat ggtttaaacg gtgctgaaaa cttaagaaat
    18361 gcacaaaaca ctgctaagca aaacttaaat acgttatcac acttaacaaa taaccaaaaa
    18421 tctgcaatct catcacaaat tgatcgtgca ggtcatgtga gtgaggtaac agctgctaaa
    18481 aatgcagcaa ctgagttaaa cacgcaaatg ggtaacttgg aacaagctat ccatgatcaa
    18541 aacacagtta agcaaagtgt taactttact gatgcagata aagctaaacg tgatgcgtat
    18601 acaaatgcgg taagcagagc agaaacaatt ctgaataaaa cgcaaggtgc aaatacttca
    18661 aaacaagatg ttgaagcagc tattcaaagt gttactagtg ctaaaaatgc attgaatggt
    18721 gatcaaaatg tcacaaatgc gaagaataca gctaaacatg cattaaataa cttaacgtct
    18781 attaataatg cacaaaaacg taacttaaca actaaaattg atcaagcaac aactgtagct
    18841 ggtgtagaag cggtttctaa tacaggtacg caattgaata cagcgatggc taacttgcaa
    18901 aatggtatta atgataaaac aaatacacta gcgagcgaaa actatcatga tgctgattca
    18961 gataagaaaa ctgcttatac tcaagccgtt acgaacgcag aaaatatttt aaataaaaat
    19021 agtggatcaa atttagacaa agttgccgtt gaaaacgcgt tgtcacaagt aacaaatgca
    19081 aaaggtgccc taaatggtaa ccataattta gagcaagcta aatcaaatgc aaacactact
    19141 ataaacggac ttcaacattt aacaactgca caaaaagata aattgaaaca acaagtgcaa
    19201 caagcacaaa atgttgcagg tgtagatact gttaaatcaa gtgccaacac attaaatggt
    19261 gctatgggta cgttaagaaa tagcattcaa gataacacag gtacgaaaaa tggccaaaac
    19321 tatcttgatg ctacagaaag taacaaaaca aactataaca atgctgttga tcgtgctaat
    19381 ggtgtcatta atgcaacaag caatccaaat atggatgcta atgcaattaa ccaaatcgct
    19441 acacaagtga catcaacgaa aaatgcatta gatggtacac ataatttaac acaagcgaaa
    19501 caaacagcaa caaatgccat cgatggtgct actaacttaa ataaagcgca aaaagatgcg
    19561 ttgaaagcac aagtgacaag tgcgcaacgt gttgcaaatg taacaagtat ccaacaaact
    19621 gcaaatgaac ttaatacagc tatgggtcaa ttacaacatg gtattgatga tgaaaatgca
    19681 acaaaacaaa ctcaaaaata tcgtgacgct gaacaaaata agaaaactgc ttatgatcaa
    19741 gctgtagctg ctgcgaaagc aattttaaat aaacaaactg gatcaaattc agataaagca
    19801 gcagttgacc atgcattaca acaagtaaca agtacgaaag atgcattgaa tggtgatgct
    19861 aaactggcag aagcgaaagc ggcagctaaa caaaacttag gcactttaaa ccatattacg
    19921 aatgcacaac gtactgcgtt agaaggtcaa atcaatcaag cgacgactgt tgatggcgtt
    19981 aatactgtga aaacaaatgc aaatacatta gacggcgcaa tgaatagctt gcaaggttca
    20041 atcaatgata aagatgcgac attaagaaat caaaattatc ttgatgcaga tgaatcaaaa
    20101 cgaaatgcat atacgcaagc tgtcacagcg gctgaaggca ttttaaataa acaaactggt
    20161 ggtaacacat ctaaagcaga cgttgataat gcattaaatg cagttacaag agcgaaagcg
    20221 gctttaaatg gtgctgacaa cttaagaaat gcgaaaactt cagcaacaaa tacgattaat
    20281 gggttaccac acttaacaca attacaaaaa gacaacttga agcatcaagt tgaacaagcg
    20341 caaaatgtag ctggtgtaaa tggtgttaaa gataaaggta atacgttaaa tactgccatg
    20401 ggtgcattac gtacaagtat ccaaaatgat aatacgacga aaacaagtca aaattatctt
    20461 gatgcatctg atagcaacaa aaataattac aatactgctg taaataatgc aaatggtgtt
    20521 attaatgcaa cgaacaatcc aaatatggat gctaatgcga ttaatggcat ggcaaatcaa
    20581 gtcaatacaa caaaagcagc gttaaatggt gcacaaaact tagctcaagc taaaacaaat
    20641 gcgacgaaca caattaacaa cgcacatgac ttaaaccaaa aacaaaaaga tgcattaaaa
    20701 acacaagtta acaatgcaca acgtgtatct gatgcaaata acgttcaacg tacagctact
    20761 gaattgaaca gtgcgatgac agcacttaaa gcagctattg ctgataaaga aagaacaaaa
    20821 gcaagcggta attatgtcaa tgctgatcaa gaaaaacgtc aagcgtatga ttcaaaagtg
    20881 actaacgctg aaaatattat tagtggtaca ccgaatgcga cattaacagt caatgacgta
    20941 aatagtgcgg catcacaagt caatgcggct aaaacagcat taaatggtga taacaactta
    21001 cgtgtagcga aagagcatgc caacaataca attgatggct tagcgcaatt gaataatgca
    21061 caaaaagcaa aattaaaaga acaagttcaa agtgcaacta cattagatgg cgttcaaact
    21121 gttaaaaata gttctcaaac gttgaataca gcgatgaaag gcttaagaga tagtattgcg
    21181 aatgaagcaa caattaaagc aggtcaaaac tacactgacg caagtccaaa taatcgtaac
    21241 gagtacgaca gtgcagttac tgcagcaaaa gcaatcatta atcaaacatc gaacccaacg
    21301 atggaaccaa atactattac gcaagcaaca tcacaagtga caactaaaga acatgcatta
    21361 aatggtgcgc aaaacttagc tcaagctaag acaactgcga aaaacaactt aaataactta
    21421 acatcaatta acaatgcaca aaaagatgcg ttaacgcgta gcattgatgg tgcaacaaca
    21481 gtagctggtg taaatcaaga aactgccaaa gcaacagaat taaataacgc aatgcacagt
    21541 ttacaaaatg gtatcaatga tgagacacaa acaaaacaaa ctcagaaata cctagatgct
    21601 gagccaagta agaaatcagc ttatgatcaa gctgtaaatg cagcgaaagc aattttaaca
    21661 aaagctagtg gtcaaaatgt agacaaagca gcagttgaac aagcattaca aaatgtgaac
    21721 agtacgaaga cggcgttgaa cggtgatgcg aaattaaatg aagctaaagc cgctgcgaaa
    21781 caaacgttag gtacattaac acacattaat aatgcacaac gtacagcgtt agataatgaa
    21841 attacacaag caacaaatgt tgaaggtgtt aatacagtta aagccaaagc gcaacaatta
    21901 gatggtgcta tgggtcaatt agaaacatca atacgtgata aagacacgac gttacaaagt
    21961 caaaattatc aagatgctga tgatgcgaaa cgaactgcat attctcaagc agtaaatgca
    22021 gcagcaacta ttttaaataa aacagctggc ggtaatacac ctaaagcaga tgttgaaaga
    22081 gcaatgcaag ctgttacaca agcaaatact gcattaaacg gtattcaaaa cttagaacgt
    22141 gcgaaacagg ctgctaacac agcgattaca aatgcttcgg acttaaatac aaaacaaaaa
    22201 gaagcattaa aagcacaagt aacaagtgca ggacgagtat ctgcagcaaa tggtgttgaa
    22261 catactgcga ctgaattaaa tactgcgatg acagctttaa aacgtgccat tgctgataaa
    22321 gctgagacaa aagctagtgg taactatgtc aatgttgatg cgaataaacg ccaagcatat
    22381 gatgaaaaag tgacagctgc agaaaatatc gttagtggta caccaacacc aacgttaaca
    22441 ccatcagatg ttacaaatgc agcaacacaa gtaacgaatg cgaagacgca gttaaacggt
    22501 aatcataatt tagaagtagc gaaacaaaat gctaacacag caattgatgg tttaacttct
    22561 ttaaatggtc cgcaaaaagc taaacttaaa gaacaagtgg gtcaagcgac gacgttgcca
    22621 aatgttcaaa ctgttcgtga taatgcacaa acattaaaca ctgcaatgaa aggtctacga
    22681 gaaagcattg cgaatgaagc aacgattaaa gcagatcaaa actacacgga tgcaagtcaa
    22741 agtaaacaaa ctgactacaa caatgcagtc actgcagcaa aagcaatcat tggtcaaaca
    22801 actagtccaa caatgaatgc gcaagaaatc aatcaagcga aagaccaagt gacagctaaa
    22861 caacaagcgt taaacggtca agaaaactta agaactgcgc aaacaaatgc gaagcaacat
    22921 ttgaatggct taagtgactt aactaatgct caaaaagaag cagccaaacg ccaaatcgaa
    22981 ggtgcaacgc atgttaatga agtaacacaa gcgcaaaata atgcggacgc attaaataca
    23041 gctatgacga acttgaaaaa tggtattcaa gatcaaaata cgattaagcg aggtgttaac
    23101 ttcactgatg cagatgaagc gaaacgtaat gcatatacaa atgcagtgac gcaagctgaa
    23161 caaattttaa ataaagcaca aggtccaaat actgcaaaag acggtgtcga aactgcgtta
    23221 caaaatgtac aacgtgctaa aaacgatttg aacggtaatc aaaatgttgc gaatgctaag
    23281 acaactgcga aaaatgcatt aaataattta acatcaatta ataatgcaca aaaagaagca
    23341 ttgaaatcac aaattgaagg tgcgacaaca gttgcaggtg taaatcaagt gtctacaacg
    23401 gcatctgaat taaatactgc aatgagcaac ttacaacgtg gtatcaacga tgaagcagct
    23461 acaaaagcag ctcaaaaata tactgatgca gatagagaaa aacaaacagc atacaatgat
    23521 gccgtaacag cagctaaaac gttattaaat aaaacagctg gttcaaatga taataaagca
    23581 gccgttgaac aagcattaca acgtgtgaat actgcgaaaa atgcattaaa tggtgatgcg
    23641 cgcttaaatg aagcgaagaa aacagctaaa caacaattag cgacaatgtc acatttaact
    23701 gatgctcaaa aagcaaactt aacatcgcaa attgaacgcg gtacgactgt tgcaggtgtt
    23761 caaggtattc aagctaatgc tggtacttta aatcaagcaa tgaatcaatt aagacaaagt
    23821 attgcttcta aagatgcgac taaatcaagt gaagattatc aagacgcgaa tacagattta
    23881 caaaatgcat acaaccgtgc agtatcagat gctgaaggta ttattagtgc aacgaataac
    23941 cctgaaatga atccagatac gattaatcaa aaagcgagcc aagtgaatag tgcgaagtca
    24001 gcattgaacg gtgacgaaaa attagcagcc gcaaaacaaa ctgcgaaaac agatatcggt
    24061 cgtttaacag acttaaacaa tgcccaacga actgcggcaa atgcagaagt ggatcaagca
    24121 ccaaaccttg cagcggtaac agcagctaaa aataaagcga catcgttaaa tacagcgatg
    24181 ggtaatttga aacatgcact tgctgaaaag gataatacga agcgaagtgt caattacaca
    24241 gatgcggatc gaccaaaaca acaagcgtat gacactgcag ttacacaagc cgaagcaatt
    24301 actaatgcca atggcagcaa cgcgaatgaa acacaagttc aagcagcgct taaccaattg
    24361 aatcaagcta aaaatgactt gaatggtgat aataaagttg ctcaagctaa agaagcagcg
    24421 aaacgtgcat tagcttcata taataacttg aataatgcgc aatcaactgc agcaactagt
    24481 caaattgaca atgcaacgac agtagcaggc gtaactgctg cacaaaatac tgctaatgaa
    24541 ttaaatacag ctatgggtca acttcaaaat agtattaatg accaaaacac tgttaaacaa
    24601 caagtgaact ttacagatgc tgaccaaggt aagaaagatg cttacacaaa tgctgttacg
    24661 aatgctcaag gtattttaga taaagcacac ggtcaaaata tgacaaaagc acaagttgaa
    24721 gctgcattaa atcaagtaac gactgctaag aatgctttaa acggtgacgc aaatgtaaga
    24781 caagcaaaat cagatgcgaa agcaaactta ggtacattaa cacacttaaa taatgcacaa
    24841 aaacaagatt taacatcaca aatcgaaggc gcaacaacag tcaacggtgt aaatggtgtt
    24901 aaaacgaaag cacaagactt agatggtgca atgcaacgat tagagtcagc aatcgcaaat
    24961 aaagatcaaa ctagagcgag cgaaaactac atcgacgcag atccaactaa gaaaacagca
    25021 tttgataatg ccatcacaca agctgaatct tacttaaata aagatcatgg tgcgaataaa
    25081 gataagcaag ctgttgaaca agcaattcaa agtgtaacga ctgctaagaa tgctttaaac
    25141 ggtgacgcga acttacaacg cgctaaaact gaagctacac aagctatcga taacttgaca
    25201 catttgaata caccacaaaa aacagcgtta aaacaacaag tgaacgctgc gcaacgtgta
    25261 tcaggtgtaa ctgatctgaa aaatagtgct acatcactta ataatgcgat ggatcaatta
    25321 aaacaagcaa ttgctgatca tgacacaatt gttgctggtg gtaattacac taatgcaagt
    25381 cctgataagc aaggtgctta tactgatgca tataatgctg cgaaaaacat tgtaaatggt
    25441 tcacctaatg tggttacaaa tgcagcagat gttacagcag caacacaacg tgttaataat
    25501 gctgaaacag gtttaaatgg tgattcaaac ttagcaactg cgaagcaaca agctaaagat
    25561 gcattacgtc aaatgacgca tttatctgct gcacaaaaac aaagtattac tggtcaaatt
    25621 gatagtgcga cacaagtaac tggcgttcaa agtgtaaaag acaatgcaac aaatcttgac
    25681 aatgcaatga atcaacttcg aaatagtatt gcgaataaag atgaagttaa agcgagtcag
    25741 ccatatgttg atgcagatac agataaacaa aatgcataca acacagctgt tacaagtgct
    25801 gaaaatatca ttaatgcaac gagtcagccg acacttgatc catctgcagt aacacaagca
    25861 gctaatcaag tgaacactaa caaaactgcg cttaatggtg tacaaaactt agcgaataaa
    25921 aagcaagaaa cgactgctaa catcaaccaa ttaagtcatt taaataatgc tcaaaagcaa
    25981 gatttaaata cgcaagtgac aaatgcacca aatattagca cagtaaatca agtgaaaact
    26041 aaagctgaac aattagatca agcaatggaa cgtttaatca acggaatcca agacaaagat
    26101 caagtgaaac aaagtgttaa ctttacagat gcagatccag aaaaacaaac agcatacaac
    26161 aatgcggtaa cggctgctga aaatattatt aatcaagcaa atggtacaaa tgcgaaccaa
    26221 tcacaagttg aagcagcact ttcaactgta acaactacta aacaagcgtt gaatggtaat
    26281 agaaaagtaa cagatgctaa aaacaatgca aaccaaacat tatctacatt agataactta
    26341 aacaatgcac aaaaaggtgc tgttactgga aacatcaatc aagcgcacac tgtagctgaa
    26401 gtaacgcaag ccattcaaac agctcaggaa ctgaatacag cgatgggtaa cttgaaaaat
    26461 agcttgaatg ataaagacac tacacttggc agtcaaaact ttgcagatgc agatccagag
    26521 aagaaaaatg catacaatga agcggttcat aatgctgaaa atattttaaa taaatctaca
    26581 ggtacaaacg tgcctaaaga tcaagttgaa gcagctatga atcaagtgaa tactacaaaa
    26641 gcagcgctta atggtactca aaaccttgaa aaagctaaac aacacgcaaa tacagcaatt
    26701 gacggtttaa gccatttaac aaatgcacaa aaagatgcat taaaacaatt ggtacaacaa
    26761 tcgactactg ttgcagaagc acaaggtaat gaacaaaaag caaacaatgt tgatgcagca
    26821 atggacaaat tacgtcaaag tattgcagat aatgcgacaa caaaacaaaa ccaaaattat
    26881 actgatgcaa gtccgaataa aaaggatgcg tacaataatg ctgtcacaac tgcacaaggt
    26941 attattgatc aaactacaag tccaacttta gatccgactg ttatcaatca agctgctgga
    27001 caagtaagca caactaaaaa tgcattaaat ggtaatgaaa acctagaggc ggcgaaacaa
    27061 caagcgacac aatcattagg ttcattagac aacttaaata atgcgcaaaa acaaacagtt
    27121 actgatcaaa ttaatggcgc gcatactgtt gatgaagcaa atcaaattaa gcaaaatgcg
    27181 caaaacttaa atacagcgat gggtaacttg aaacaagcga ttgctgacaa agatgctacg
    27241 aaagcaacag taaacttcac tgatgcagat caagcaaaac aacaagcata taacactgct
    27301 gttacaaatg ctgaaaacat tatttcaaaa gctaatggtg gcaatgcaac acaaactgaa
    27361 gttgaacaag caatccaaca agtaaatgca gcaaaacaag cattaaatgg taatgccaac
    27421 gttcaacatg caaaagacga agcaacagca ttaattaata gctctaatga ccttaaccaa
    27481 gcacaaaaag acgcattaaa acaacaagtt caaaatgcaa ctactgtagc tggtgtaaac
    27541 aatgttaaac aaacagcaca agagttaaac aatgcgatga cacaattaaa acaaggcatt
    27601 gcagataaag aacaaacaaa agctgatggt aactttgtca atgcagatcc tgacaagcaa
    27661 aatgcatata atcaagcagt agcaaaagct gaagcattaa ttagtggtac gcctgatgta
    27721 gtcgttacac ctagcgaaat tactgcagct ttaaataaag ttacgcaagc taaaaatgat
    27781 ttgaatggta atacgaactt agcaacggcg aaacaaaatg ttcaacaagc tattgatcaa
    27841 ttgccaaact tgaatcaagc gcaacgtgat gaatacaaca aacaaattac gcaagcaact
    27901 cttgtaccaa acgtcaatgc tattcaacaa gcggcgacaa cgcttaatga cgcgatgaca
    27961 caattgaaac aaggtattgc gaataaagca caaattaaag gtagcgagaa ctatcacgat
    28021 gctgatactg acaagcaaac agcatatgat aatgcagtaa caaaagcaga agaattgtta
    28081 aaacaaacaa caaatccaac aatggatcca aatacaattc aacaagcatt aactaaagtg
    28141 aatgacacaa atcaagcact taacggtaat caaaaattag ctgatgctaa acaagcagct
    28201 aagacaaatc ttggcacatt agatcattta aatgatgctc aaaaacaagc gttaacaaca
    28261 caagttgaac aagcaccaga tattgcaaca gttaataatg ttaagcaaaa tgctcaaaat
    28321 ctgaataatg ctatgactaa cttaaacaat gcattacaag ataaaactga gacattaaat
    28381 agcattaact ttactgatgc agatcaagct aagaaagatg cttatactaa tgcggtagca
    28441 catgcagaag gtattttatc taaagcaaat ggcagcaatg caagtcaaac tgaagtggaa
    28501 caagcgatac aacgtgtgaa cgaagcgaaa caagcattga atggtaatga caatgtacaa
    28561 cgtgcaaaag atgcagcgaa acaagtaatt acaaatgcaa atgatttaaa tcaagcgcaa
    28621 aaagatgcat taaaacaaca agtcgatgct gcgcaaactg ttgcaaatgt aaacacaatt
    28681 aagcaaacag cacaagattt aaatcaagca atgacacaat tgaagcaagg tattgcagat
    28741 aaagaccaaa ctaaagcaaa tggtaacttt gtcaatgcag atactgataa gcaaaatgca
    28801 tataacaatg cggtagcaca tgctgaacaa atcattagtg gtacaccaaa tgcaaacgtg
    28861 gatccacaac aagtggctca agcgttacaa caagtgactc aagctaaggg tgatttaaac
    28921 ggtaaccata acttacaagt tgctaaagac aatgcgaata ctgccattga tcagttacca
    28981 aacttaaatc aaccacaaaa aacagcgtta aaagaccaag tgtcacatgc agaacttgtt
    29041 acaggtgtta atgctattaa gcaaaatgct gatgcattaa ataatgcaat gggtacgttg
    29101 aaacaacaaa ttcaagcaaa cagtcaagta ccgcaatcag ttgactttac acaagcggat
    29161 caagacaaac aacaagcata taacaatgca gctaaccaag cgcaacaaat tgcaaatgga
    29221 acaccaacac ctgtattgtc gcctgataca gtaacacaag cagttacaac tatgaatcaa
    29281 gcgaaagatg cattaaacgg tgatgaaaaa ttagcgcaag cgaaacagga tgctttagca
    29341 aatctggata cgttacgtga cttaaatcaa ccacaacgtg atgcgttacg taatcaaatc
    29401 aaccaagcac aagcgttagc tacagtcgaa caaactaaac aaaatgcaca aaatgtgaat
    29461 gcaacaatgg gtaacttgaa acaaggtatt gcaaataaag atactgtcaa agcaagtgag
    29521 aactatcatg atgctgatgc cgataagcaa acagcatata caaatgcagt gtctcaagcg
    29581 gaaggtatta tcaatcaaac gacaaatcca acgcttaatc cagatgaaat aacacgtgca
    29641 ttaactcaag taactgatgc taaaaatggc ttaaacggtg aagctaaatt agcaactgaa
    29701 aagcaaaatg ctaaagatgc cgtaagtgga atgacgcatt taaacgatgc tcaaaaacaa
    29761 gcattaaaag gtcaaatcga tcaatcgcct gaaattgcta cagtgaacca agttaaacaa
    29821 acagcaacga gcctagatca tgcaatggat caattatcac aagctattaa tgataaagct
    29881 caaacattag cggacggtaa ttacttaaat gcagatcctg acaaacaaaa tgcgtataaa
    29941 caggcagtag caaaagctga agcattattg aataaacaaa gtggtactaa tgaagtacaa
    30001 gcccaagttg aaagtatcac taatgaagtg aaaacagcga aacaagcatt aaatggtaat
    30061 gataatttag cgaatgctaa gcaacaagcg aaacaacaat tggcgaattt aacacactta
    30121 aatgatgctc aaaaacaatc atttgaaaat caaataacac aagcgccact tgttacagat
    30181 gtcactacaa ttaatcaaaa agcgcaaacg ttagatcatg cgatggaatt attaagaaat
    30241 agtattgcag ataaccaagc gacattagca tctgaagatt atcatgatgc aactgcgcaa
    30301 agacaaaatg actataacca agctgtaaca gctgctaata atatcattaa tcaaacaaca
    30361 tcacctacga tgaatccaga tgatgttaat cgtgcaacaa ctcaagtgaa taacacgaaa
    30421 gttgcattag atggtgatga aaaccttgta gcagctaagc aacaagcgaa caatagactt
    30481 gatcaattag atcatttaaa taatgcgcaa aagcaacagt tacaatcaca aattacgcaa
    30541 tcatctgata ttgcagcagt taatggtcac aagcaaactg cagaatcttt aaataccgca
    30601 atgggtaact taatcaatgc gattgcagat catcaagccg ttgaacaacg tggtaacttc
    30661 atcaatgctg atactgataa acaaactgct tatactacag cagtaaatga agcagaagca
    30721 atgattaaca aacaaactgg tcaaaatgcg aaccaaacag aagtagaaca agctattact
    30781 aaagttcaaa caacacttca agcgttaaat ggagatcata atttacaagt tgctaaaaca
    30841 aatgcgacgc aagcaattga tgctttaaca agcttaaatg atcctcaaaa aacagcatta
    30901 aaagaccaag ttactgctgc aacattagta actgcagttc atcaaattga acaaactgcg
    30961 aatacgctta accaagcaat gcatggctta agagaaagta ttcaagataa cgcaacaact
    31021 caagcaaata gcaaatatat caacgaagat caaccagagc aacaaaacta cgatcaagca
    31081 gtgcaagctg caaataacat tatcaatgag caaacagcga cattagataa taatgcgatt
    31141 aatcaagcag caacaactgt gaatacaacg aaagcagcat tacatggtga tgtgaagtta
    31201 caaaatgata aagatcgtgc gaaacaaacg gttagtcaat tagcacatct aaacaatgct
    31261 caaaaacata tggaagatac gttaattgat agtgaaacaa ctagatcagc cgttaaccat
    31321 gatttgactg aagcacaagc attagatcaa cttatggata cattacaaca aagtattgct
    31381 gacaaagatg caacacgtgc gagcagtgcc tatgtcaatg cagaaccgaa taaaaaacaa
    31441 gcatatgatg aagcagttca aaatgctgag tctatcattg caggattaac taatccaact
    31501 atcaataaag gcaatgtttc aagtgcgaca caagcagtaa catcatctaa aaatgcatta
    31561 gacggtgttg aacgattagc gcaagataag caaactgctg gaaattctct aaatcattta
    31621 gatcaattaa cgccagcaca acaacaagcg ctagaaaatc aaattaataa tgcaacaact
    31681 cgtgataaag tggctgaaat cattgcacaa gcgcaagcat taaatgaagc gatgaaagca
    31741 ttaaaagaaa gtattaaaga tcaaccacaa actgaagcaa gtagtaaatt tattaatgaa
    31801 gatcaagcac aaaaagatgc ttatacgcaa gctgtacaac acgcgaaaga tttgattaac
    31861 aaaacaactg atcctacatt agctaaatca atcattgatc aagcgacaca ggcagtaact
    31921 gatgctaaaa acaacttaca tggtgatcaa aaattagctc aagataagca acgtgcaaca
    31981 gaaacgttaa ataacttgtc taacttgaat acaccacaac gtcaagcact tgaaaatcaa
    32041 atcaataatg cagcaactcg tgacaaagta gcacaaaaat taactgaagc acaagcactt
    32101 aaccaagcaa tggaagcttt acgtaatagc attcaagatc aacagcaaac agaagcgggt
    32161 agcaagttta tcaatgaaga taagccgcaa aaagatgcat accaagcagc agttcaacat
    32221 gccaaagatt tgattaatca aactagcaat ccaacgcttg ataaagcaca agttgaacaa
    32281 ttgacacaag ctgttaacca agctaaagat aacctacatg gtgatcaaaa acttgcagac
    32341 gataaacaac atgcagttac tgatttaaat caattaaatg gtttgaacaa tccgcaacgt
    32401 caagcgcttg aaagtcaaat aaacaatgca gcaactcgtg gtgaagtagc acaaaaatta
    32461 actgaagcac aagcacttaa ccaagcaatg gaagctttac gtaatagcat tcaagatcaa
    32521 cagcaaacag aatctggtag caagtttatt aatgaagata aaccgcaaaa agatgcttac
    32581 caagcagcag ttcaaaatgc aaaagattta atcaaccaaa caggtaatcc aacactcgac
    32641 aaatcacaag tagaacaatt aacacaagca gtaacaactg caaaagataa tctacatggt
    32701 gatcaaaaac tagctcgtga tcaacaacaa gcggtaacga ctgttaatgc attaccaaac
    32761 ttaaatcatg cacaacaaca agcattaact gatgcaatta atgcagcgcc tacaagaaca
    32821 gaggttgcac aacatgttca aactgctact gaacttgatc acgcgatgga aacattgaaa
    32881 aataaagttg atcaagtgaa aacagataag gcccaaccaa attacactga agcatcgacg
    32941 gataaaaaag aagcagtgga tcaagcgtta caagctgcac aaagcattac agaacctaat
    33001 aatggttcaa atgcaaataa agatgctgta gaacaagcat taactaagct tcaagaaaaa
    33061 gaaaatgagt taaatggtaa tgagagagtc gctgaagcta aaacacaagc gaaacaaaca
    33121 gttgaccaat taacacattt aaatgctgat caaattgcaa ctgcaaaaca aaacattgat
    33181 caagcgatga aacttcaacc aatcgctgaa ttagtagatc aagcaacgca attgaacaaa
    33241 tctatggatc aattacaaca agcggtcaat gatcatacaa acgttgagca aactgtagat
    33301 tacacgcaag cagattcaga taagcaaaat gcttataaac aagctattgc agatgctgaa
    33361 aatgtattaa aacaaaatgc gaataaggaa caagtggatc aagcacttca aaacatttta
    33421 aatgcaaaac aagcattaaa tggtgatgaa cgcgtagcac ttgctaaaac aaatggtaaa
    33481 catgatattg accaattaaa tacattaaac aatgcacaac aagatggatt taaaggcaga
    33541 attgatcaat ctaatgactt aaataaacaa attgtagatg aagctaaagc tctaaatcgt
    33601 gcaatgaatc aattgtctca agaaatcact ggcaatgaag gacgtacgaa aggtagtacg
    33661 aactatgtca atgcagatac acaagttaaa cgcgtgtacg atgatgcagt tgataaagcg
    33721 aaggaagcac taaataaagc gacaggtcaa aacttaactg cagaagaagt tatcaagttg
    33781 aacgatgcgg taacagcagc gaaacaggca ttaaatggtg aagaaagact taacaagcgt
    33841 aagtctgaag cattacaaag attggatcaa ttaacacatc taaacaatgc tcaaagacaa
    33901 ttagcaacac aacaaattaa taatgctgaa acattaaata aagcgtctcg agcaattaat
    33961 agagctgttc aattagatga tgcaatgggt gcagtacaac agtatattga tgatcatcat
    34021 tttgatgtca ttagcagtac aaattacatc aatgcagacg ataacttgaa agcaaattat
    34081 gataatgcca ttacaaatgc agcgcatgag ttagataaag ttcaaggtag tgcaatcacg
    34141 aaagctgagg cagaacaatt aaaacaaaat attatagatg cgcaacaagc cttaaatggt
    34201 gatcaaaatc ttgcaactgc taaagataaa gccaatgcct ttgttgatac attaaatggt
    34261 ttaaatcaac aacaacaaga tcttgcacat caagcaatta ataatgccga tactgtaaca
    34321 ggtatagcga atattattaa tgatcaaatc gacttgaata acgctatgga aacattgaaa
    34381 cacttagttg acaatgaaat tccaactgca gaacaaacta tcaattacca aaacgctgac
    34441 gacgttgcta aatcaatctt tgatgatgca aaacgtctgg caaatacatt gctaaatagt
    34501 gataacacaa atgtgaatga tattaacggc gcaattcaag cagtcaatga tgcaatccaa
    34561 aatcttaatg gtgatcaacg tctacaagaa gctaaggaca aagcaattca aaatgttaac
    34621 aaagtcttag cagataaatt gaaagaaata gaagcttcaa atgcgacgga tcaagacaag
    34681 cttattgcga aaaataaagc agaagaattg gcaaacagta tcattaacaa cattaataaa
    34741 gcaacaagta atcaggatgt atctcaagtt caaacagctg gcaaccatgc gattgaacaa
    34801 gtgcatgcca atgaaatacc gaaagctaaa attgatgcaa ataaagatgc tgataagcaa
    34861 gtacaagcat taattgacga aattgatcga aatccaaatc taacagataa ggaaaaacaa
    34921 gcacttaaag atcgaataaa tcaaatattg caacaaggtc ataacggcat caacaatgcg
    34981 atgactaaag aagaaattga acaagccaaa gcacaacttg cacaagcgtt acaagaaatt
    35041 aaagatttag tgaaagctaa agaaaatgcg aaaaatgcaa ttaaagcatt agcaaatgcg
    35101 aagcgtgatc aaatcaattc aaaccctgat ttaacacctg agcaaaaagc aaaagcgctc
    35161 aaagaaattg acgaagctga aaaacgagca ctagaaaata ttgaaaatgc tcaaactaaa
    35221 gatcaattaa atcaaggatt aaatttagga ttagatgata ttagaaatac tcatgtatgg
    35281 gaagttgata cacaacctgc tgtaaatgaa atttttgacg caactcctga acaaatcctt
    35341 gtaaatggtg aactcattgt acatcgtgat gacatcatta cagaacaaga tattctagca
    35401 catataaact tagttgatca gcttacagca gaagttattg atacaccgtc aaccgcaaca
    35461 atttctgata gcttaacagc aaaagtcgaa gtaacattac ttgatggatc aaaagtaatt
    35521 gttaatgttc ctgtgaaagt agtagaaaaa gaattggcag tagtcaaaca acaggcaatt
    35581 gaatcaattg aaaatgcggc acaacaaaag attaatgata tcaataatca cacaacatta
    35641 acaccagaac aaaaagaagc tgcgattgcg gaagttaata agcttaaaca acaagctatt
    35701 gagcaaatta acaatgcaac agatgttcat tcggtggaag aagttcaaca acaagaacaa
    35761 acgcatattg aacaatttaa tccagagcaa tttacaattg accaagccaa atcaaatgcc
    35821 attaaatcaa ttactgatgc tattcaacat atgattgatg aaattaatgc tagtaaggat
    35881 ttaactgata aagagaaaca agaagctata tctaagttaa atcaattaaa agaacaggca
    35941 attcaagcga ttcaacgtgc gcaaagtatc gatgaaatca cacaacaatt agagcaattc
    36001 aaagcgcaaa taaaagcagc aaatccattt gctaaagaat tggaaaaacg taaaaaagta
    36061 gcgatttcaa aaattaaaga tatttcgaca gatgcaattg aacgcattaa aaatagttca
    36121 actggaactg ctgaagaaag acaagcagca atgaatcgaa ttaacgaaat tgtacttgaa
    36181 acaatcagag atattaataa tgcgcaaacg ccacaacaag ttgaggctgc attgaataat
    36241 ggtatcgcac gaattttggc agtacaaatt gttacatcta ataatagcaa g
//
LOCUS       DAPSKH010000025        36198 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPSKH010000025 DAPSKH010000000
VERSION     DAPSKH010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 36198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36198
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.025"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(247..1203)
                     /locus_tag="RPH49_001268"
     CDS             complement(247..1203)
                     /locus_tag="RPH49_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124431.1"
                     /translation="MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDF
                     KEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVED
                     LRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQ
                     EAQASQAKVLAESTNKVDAKSATDEKADSKDSKVAGVNTSTDAKTDTKADNAGDGTTT
                     KVDKEDQISATEAIEKASVEQSKNDNAAETSNKEATVDAEAQHDAEQQVAEAHAEASK
                     QATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL"
     gene            complement(1321..1983)
                     /locus_tag="RPH49_001269"
     CDS             complement(1321..1983)
                     /locus_tag="RPH49_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124432.1"
                     /translation="MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNK
                     TENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHE
                     LNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHP
                     TNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRK
                     PF"
     gene            complement(2126..2533)
                     /locus_tag="RPH49_001270"
     CDS             complement(2126..2533)
                     /locus_tag="RPH49_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDY5124433.1"
                     /translation="MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLH
                     DSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAV
                     RDKSSHQEVHENNSAYEEIDITHFAEASKGPKA"
     regulatory      2713..2815
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            3046..3624
                     /gene="xpt"
                     /locus_tag="RPH49_001271"
     CDS             3046..3624
                     /gene="xpt"
                     /locus_tag="RPH49_001271"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDY5124434.1"
                     /translation="MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYE
                     QFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKN
                     KTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQN
                     GHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE"
     gene            3624..4892
                     /locus_tag="RPH49_001272"
     CDS             3624..4892
                     /locus_tag="RPH49_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDY5124435.1"
                     /translation="MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDI
                     FMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVII
                     IAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTL
                     IIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGF
                     SFDVTSTLVFFIVAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIF
                     NSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAM
                     IAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQ
                     NGIVLGAISAIILNFFFNGIKYKQTEENVK"
     gene            4930..6396
                     /gene="guaB"
                     /locus_tag="RPH49_001273"
     CDS             4930..6396
                     /gene="guaB"
                     /locus_tag="RPH49_001273"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDY5124436.1"
                     /translation="MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNI
                     PVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFL
                     TPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQE
                     NLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHG
                     RLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLV
                     AGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHG
                     KAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGS
                     LGAMEKGSNDRYFQDDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSH
                     DLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF"
     gene            6421..7962
                     /gene="guaA"
                     /locus_tag="RPH49_001274"
     CDS             6421..7962
                     /gene="guaA"
                     /locus_tag="RPH49_001274"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019166941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDY5124437.1"
                     /translation="MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIE
                     EIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVER
                     ANEREYGKAIINAKSDELFVGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIE
                     DKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGD
                     RRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNI
                     IRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIE
                     SGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFP
                     GPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGD
                     YRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPS
                     TIEWE"
     gene            complement(8202..8594)
                     /locus_tag="RPH49_001275"
     CDS             complement(8202..8594)
                     /locus_tag="RPH49_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000888757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124438.1"
                     /translation="MLEDNGDIRLLYQSIEELASVLGQSQFETKTVSLIFVQMDLRYS
                     VFEKVQTDFMKYLAHKNSDEIKYIDLIKIIENALPEDKELSINVINSIIIGFANNYYP
                     ILQSLVPEIQSSYGITINKNFNIDSIDF"
     gene            complement(8616..9095)
                     /locus_tag="RPH49_001276"
     CDS             complement(8616..9095)
                     /locus_tag="RPH49_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124439.1"
                     /translation="MKITKTIGSLVLTAVLLTSVSPLTNANEIQTNNTKTAHQSYENI
                     NGVKINRNPNLPMNPEAQQRIGGTKVVKTAIKLIINNRGKAKNVIQQVGGKKAATIFD
                     KGYSGIVKELKPLLKWSEVPANAVGDAVKRGAINAGLSKGDAGIISTVVKEAIAWLF"
     gene            10023..10355
                     /locus_tag="RPH49_001277"
     CDS             10023..10355
                     /locus_tag="RPH49_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124440.1"
                     /translation="MATLKDVKTGKKEILPSTAKDKNGKKVTLIYFEKDDKLGFYVQK
                     TQKERGVGKCVSGIAGGAVTGGTTLGLAGAGVGTVTIPVIGTVSGGVVGAVGGAVGGG
                     LTGGATFC"
     gene            complement(10943..11128)
                     /locus_tag="RPH49_001278"
     CDS             complement(10943..11128)
                     /locus_tag="RPH49_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000384191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124441.1"
                     /translation="MDYALSIASEIYDRTALRHICVDWYDNKNLKEFYCNNCGFKIYQ
                     EKITKKGKLISAFYKLK"
     gene            complement(11508..11660)
                     /locus_tag="RPH49_001279"
     CDS             complement(11508..11660)
                     /locus_tag="RPH49_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124442.1"
                     /translation="MVPEEKGSITLSKEAAIIFATAKFKPFKNRIKNNPLKTNPFLKL
                     HENKKS"
     gene            complement(12189..12548)
                     /locus_tag="RPH49_001280"
     CDS             complement(12189..12548)
                     /locus_tag="RPH49_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HDY5124443.1"
                     /translation="MNIISIILIIFVALEFFYIMYLETIATTSKKTSETFNISVDKLK
                     DKNINVLLKNQGVYNGLIGVLLIYGLFISSNPKEICAAILVYIIGVAIYGGLSSNISI
                     FFKQGTLPVLALISMLW"
     gene            complement(12567..13412)
                     /locus_tag="RPH49_001281"
     CDS             complement(12567..13412)
                     /locus_tag="RPH49_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5124444.1"
                     /translation="MNIMLTGATGHLGTHITNQAIANHIDHFHIGVRNVEKVPEDWRG
                     KVSVRQLDYFNQESMVEAFKGMDTVVFIPSIIHPSFKRIPEVENLVYAAKQCGVAHII
                     FIGYYADQHNNPFHMSPYFGYAARLLATSGIDYTYVRMAMYMDPLKPYLPELMNMHKL
                     IYPAGDGRINYITRNDIARGVIAIIKNPDTWGKCYLLSGYSYDMKELAAILSEASGTE
                     IKYEPVSLETFAKMYDEPKGFGALLASMYDAGARGLLDQESNDFQQLVNDQPQTLQSF
                     LQENI"
     gene            13884..14564
                     /locus_tag="RPH49_001282"
     CDS             13884..14564
                     /locus_tag="RPH49_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL1"
                     /protein_id="HDY5124445.1"
                     /translation="MKFKAIAKASLALGMLATGVITSNVQSVQAKAEVKQQSEADLKL
                     YYSGPSFEYKKVTGYGFVEGKDRFIDFIYNGQYNKISLVGSDKDKYNEEVNPDIDVFV
                     VREGNGRQADNHSIGGVTKTNRGVYYDYIHTPILEIKKGKEEPQSSLYQIYKEDISLK
                     ELDYRLRERAIKHHGLYSKGLKQGQITITMNDGTTHTIDLSQKLEKERMGQSVDGKQI
                     QKILVEMK"
     gene            14848..15549
                     /locus_tag="RPH49_001283"
     CDS             14848..15549
                     /locus_tag="RPH49_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL2"
                     /protein_id="HDY5124446.1"
                     /translation="MKMKSIAKVSLVLGILATGVNTVTEQPVHAENKPIQVSQNSKNL
                     KAYYTQPSVEYKNVTGYISSIQPKAGTKFMNIIEGNTVNNLALVGKDKQHYHTGVHRN
                     LDIFYVNEDKRFEGSKYSIGGITEASDKAVDQIAEARVIKEDHTGEYDYDFFPFKIDK
                     EAMTLKEVDFKIRKHLIDHYGLYGEMSSGTVTVKMKYYGKYTFELDKKLQEDRMADII
                     KVTDIDRIEVIVKKA"
     gene            15839..16870
                     /locus_tag="RPH49_001284"
     CDS             15839..16870
                     /locus_tag="RPH49_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL3"
                     /protein_id="HDY5124447.1"
                     /translation="MKIRTIAKASLALGLVTTGASIVTTQSANAEVASALKAGQLAKI
                     NVSSSAVTTTTQAVNAEQNRTANTEQASKSNTEKVSTSPSIKTEQTPKSNTQKATQPT
                     PSGTTQPLPNAQPQSPQSTPNASTSPSSSVETQQPQSPTTKQAQKEINPKYKDLRTYY
                     TKPSLEFEKQFGFMLKPWTTVRFMNVIPDWFIYKIALVGKDDKKYKDGPYDNIDVFIV
                     LEDNKYQLKKYSVGGITKTNSKKVDHKARISITKEDEKGKISRDDSEYKITKEEISLK
                     ELDFKLRKQLIEQHNLYGNIGSGTIVIKTKNGGKYTFELHKKLQEHRMADVIDGTSID
                     RIEVNLKSS"
     gene            17231..17935
                     /locus_tag="RPH49_001285"
     CDS             17231..17935
                     /locus_tag="RPH49_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL5"
                     /protein_id="HDY5124448.1"
                     /translation="MKIRTIVKASLALSILATGVITSTAQTVNASEHEAKYENVTKDI
                     FDLRDYYSGESKALKNVIGYHYSKGGRHYLVIDKNRKFTRVQIFGKDIERFKARKNPG
                     LDIFVVKEAENRNGTVYSYGGVTKKNQGAYYDYINAPRFQIKRDEGDGIATYGRVHYI
                     YKEEVSLKELDFKLRQYLIQNFDLYKKFPKDSKIKVIMKDGGYYTFELNKKLQTNRMS
                     DVIDGRNIEKIEANIR"
     gene            18383..19078
                     /locus_tag="RPH49_001286"
     CDS             18383..19078
                     /locus_tag="RPH49_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL7"
                     /protein_id="HDY5124449.1"
                     /translation="MKLKTLAKATLALGLLTTGVITSEGQAVKAAEKQERVQHLHDIR
                     DLHRYYSAPSFEYSNISGKVENYNGSNVVRFNQKDQNHQLFLLGKDKEEYKEGLQGQN
                     VFVVQELIDPNGRLSTVGGVTKNNNKTSETKTQLVVNKVDGGDLHASIDSFLIQKEEI
                     SLKELDFKIRQQLVNNYGLYKGTSKYGKIIINLKDENKVEIDLSDKLQFERMGDVLNS
                     KDIRGIAVTINQI"
     gene            19419..20117
                     /locus_tag="RPH49_001287"
     CDS             19419..20117
                     /locus_tag="RPH49_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL9"
                     /protein_id="HDY5124450.1"
                     /translation="MKLTALAKATLALGILTTGVFTAESKAVHAKVELDETQRKYYIY
                     MLKDYYSEESYEPTNISVKSEDYYGSNVLNFNHRNKNFKVFLLGDDKNKYKEKTHGLD
                     VFAVPELIDTKGGIYSVGGITKKNVRPVFGFVSHPGLLVKKIDPKHGFSVNELFFIQK
                     EEVSLKELDFKIRKMLVEKYRLYKGASDKGRIVINMKDEKKYVIDLSEKLSFDRMFDV
                     MDSKQIKNIEVNLN"
     gene            20484..21167
                     /locus_tag="RPH49_001288"
     CDS             20484..21167
                     /locus_tag="RPH49_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL10"
                     /protein_id="HDY5124451.1"
                     /translation="MKLTALAKATLALGILTTGTLTTEAYSGHAKQNQKSVNKHDKEA
                     LHRYYSGNFKEMKNINALRHGKNNLRFKYRGMKTQVLLPGDEYRKYQQRRHTGLDVFF
                     VQEKRDKHDISYTVGGVTKSNKTPGFVSAPLLNVTKENGEDAFVKGYPYDIKKEEISL
                     KELDFKLRKHLIEKYGLYKTKSKDGKIKINLKDGSFYNLDLRSKLKFKHMGEVIDSKQ
                     IKDIEVNLK"
     gene            21426..22982
                     /locus_tag="RPH49_001289"
                     /pseudo
     CDS             21426..22982
                     /locus_tag="RPH49_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028656.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
     gene            22975..24234
                     /locus_tag="RPH49_001290"
     CDS             22975..24234
                     /locus_tag="RPH49_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDY5124452.1"
                     /translation="MSNTQKKNVPELRFPGFEGEWEEKKLGDLTDRVIRKNKNLESKK
                     PLTISGQLGLIDQTEYFSKSVSSKNLENYTLIKNGEFAYNKSYSNGYPLGAIKRLTRY
                     DSGVLSSLYICFSIKSEMSKDFMEAYFDSTHWYREVSGIAVEGARNHGLLNVSVNDFF
                     TILIKYPSLEEQQKIGKFFSKLDRQIELEEQKLELLQQQKKGYMQKIFSQELRFKNEN
                     GNDYPDWERIKFFDVIDKVIDFRGRTPKKLNMEWSDEGYLALSAVNVKKGYIDFNVEA
                     KYGNLDLYTRWMRGNELYKGQVLFTTEAPMGNVAQVPDNKGYILSQRTIAFNSNEKIT
                     DNFLASLLSSENVYNDLLKLCSGATAKGVSQKNLNRLYVTIPHSISEQEEIAEFFRKI
                     NQLVELQKYKIEHTKSQKQVFLQKMFI"
     gene            24647..25333
                     /locus_tag="RPH49_001291"
     CDS             24647..25333
                     /locus_tag="RPH49_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL11"
                     /protein_id="HDY5124453.1"
                     /translation="MKLKNIAKASLALGILTTGMITTTAQPVKASTLEVRSQATQDLK
                     DYYKGQSFDLKNIGGYKEGNKVTFIYHNQQIDVTLTGNEKLEFNDDGEISNVDVFVVR
                     ENSDRSGITSSNGGITTSNKQDIIDNVKSVNMQITKKTSSNTETVTSSYYSISKENIS
                     LKELDFKLRKHLIDKNGLYKTEPKNSKIRVTMEDGGFYTFELNKKLQTNRMGDVIDAT
                     KIKEINVELN"
     gene            25355..26836
                     /locus_tag="RPH49_001292"
     CDS             25355..26836
                     /locus_tag="RPH49_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKLRK protein"
                     /protein_id="HDY5124454.1"
                     /translation="MRENFKLRKMKVGLVSVAITMLYIMTNGQAEASETNQKPSTNQE
                     STAVTHTEQNSKETKTAESSKNFVNLDPIKPGDQKVTGTTMPNHIILLNIDGKSVDSV
                     DGEDSSFITSKEDGKFEYPLNNRKIVHNQEIEVSSSSLDDLGEDDEEVEEDSTEKSEA
                     EEESTGAKVTYTTPRYEKAYEVPEKRLEEKDGHHQVFIEPITEGSGIIKGHTSVKGKV
                     ALSINNKFINFETNSNGGPNKEEAKSGSEGIWMPIDDKGYFNFDFKTKRFDNLELKEG
                     NDISLTFAPDDEDALKPLIFKTKVTSLEDIDKAETKYDHTKVNKVKILDNVKEDLHVD
                     EIYGSLYHTDKGKGILDKEGTKVIKGKTKFANAVVKVDSELGEAQLFPDLQVNEKGEF
                     SFDSHGAGFRLQNGEKLNFTVVDPITGELLSNEFVSKEIDIEETPEEKADREFDERLE
                     NTPAYYKLYGDKIVGFDTNDFPITWFYPLGEKKVERITPKLEK"
     gene            complement(26943..27251)
                     /gene="spn"
                     /locus_tag="RPH49_001293"
     CDS             complement(26943..27251)
                     /gene="spn"
                     /locus_tag="RPH49_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myeloperoxidase inhibitor SPIN"
                     /protein_id="HDY5124455.1"
                     /translation="MKFKKVLVATAMVGVLATGVVGYGNQADAKVYSQNGLVLHYDAN
                     FLEHELSYIDVLLDKNADQATKDNLRSYFADKGLHSIKDIINKAKQDGFDVSKYEHVK
                     "
     gene            27618..28400
                     /locus_tag="RPH49_001294"
     CDS             27618..28400
                     /locus_tag="RPH49_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5124456.1"
                     /translation="MGYLKRFTLYISIFILIVVIAGCGKSDETKEDSKEEQIKKSFAK
                     TLDMYPIKNLKDLYDKEGYRDGEFKKGDKGTWTLLTSFSKSNKPGEIDDEGMVLYLNR
                     NTKKATGYYFVNKIYDDISKNQNEKKYRVELKNNKIVLLDNVEDEKLKQKIENFKFFS
                     QYADFKDLKNYQDGSITTNENVPSYEAEYKLNNSDENVKKLRDIYPITTKKAPILKLH
                     IDGDIKGSSVGYKKIEYKFSKVKDQETTLRDYLNFGPSDEDI"
     gene            28448..29227
                     /locus_tag="RPH49_001295"
     CDS             28448..29227
                     /locus_tag="RPH49_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5124457.1"
                     /translation="MGYLKRIGLCISLLILSIFVTSCDSDNKITGDSKEAQIKKSFAK
                     TLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVVRSEMIIQPKSKSLTSRGMILYMNR
                     NTRTTTGYFSIEEIDSRKNLDERETEKKYPVKIINNKIIPTVKIKDEKLKKEIENFKF
                     FVQYGSFKGIENYENGHISYNSEGPIYSARYQLKNDDYNVKELRKRYDIPTEKAPKLL
                     LKGSGDLKGSSVGYKEIEFIFLENKKENIYFSDGLNLIPGD"
     gene            29288..30082
                     /locus_tag="RPH49_001296"
     CDS             29288..30082
                     /locus_tag="RPH49_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5124458.1"
                     /translation="MRDSKRVVLYISIMVLSIFIIGCNSSSENAKKSKEDSKEDQIKK
                     SFAKTLDMYPIKNLEDLYDKEGYRDGEFEKGDKGTWTIYTDFAKSNKAGELDSEGMVL
                     HLNRNTRTAKGYYFVRKTYNEEDKMLQRKDYRIKLKNNKIVLLDKVEDKKLKHKIENF
                     KFFGQYADFKDLKNYKNGKISSNENVPYYEAEYKIENSDRNVKKLRNVYPITTSESPT
                     LKFHIDGDIKGSSIGYKKVEYIFSKQKDNQISVSDFLNFNPSKDNQ"
     gene            30121..30918
                     /locus_tag="RPH49_001297"
     CDS             30121..30918
                     /locus_tag="RPH49_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5124459.1"
                     /translation="MRNLKRDVLYISIMALSIFIIGCDKSSVTAEKAKEDSKEDQIKK
                     SFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGTWVIRSEMTTELKDENVESKGMVV
                     RLNRNTRTTTGEYFVRIIKEDNEGKVYSDERKYPVKIDNKKIIPLKLIDDEKVKKEIE
                     EFKFFVQYGNFKELENYKDGKVSYNPEVPIYSAQYQLKNSDYNVEQLRKRYNIPTRKA
                     PKLLLKGSGNLKGSSVGYKNIEFTFVENKEENIYFTDSINFNPSEDK"
     gene            31099..31908
                     /locus_tag="RPH49_001298"
     CDS             31099..31908
                     /locus_tag="RPH49_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5124460.1"
                     /translation="MEYIKKIALYMSVLLLIIFIGGCGNMKEEQKKEANTNKTDSKEE
                     QIKKSFAKTLDMYPTENLEDFYNKEGYRDGEFKKDDKGTWLIRSEIVKQPKGKVMKTR
                     GMQLYINRNTKTAKGFFVLKEISENNNRVNKDKEEKYEVKMVGNKIIPTEQINDEKIK
                     KEIENFKFFVQYGKFKNFEKYKNGEFSYNPEAPIYSAKYQLQNDDYNVRQLRKKYDIS
                     TKEAPKLLLKGGGDLKGSSVGQKDIEFTFVERKGENIYFNDSVEFIPSEDK"
     gene            31911..33239
                     /locus_tag="RPH49_001299"
     CDS             31911..33239
                     /locus_tag="RPH49_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124461.1"
                     /translation="MSKPEYQLNPGKINANTEETSAISYFSYQIENANISGLDKVKMY
                     QQIDILKDRYKFPSNLEYVDSYTDSLTGVTTSAFLNKDTGKVTLGMTGTNLQDEAFKK
                     LKEGEFSRQNFTNALETVKDGYADLKILYSPASDQNYRYANTQEFINKIKSKYDIDFI
                     TGHSLGGRDAVVLGMSNGIPNIVVYNPAPISITSLNPNSPDGKRLLELYKNYKGNITR
                     FVAENDALTENLKKYKHYVFFGNDKVFKNGKGHGMEGFLTKEEQKAIKKELKKLQGYA
                     EENNKSFVKHSNNAISKLASIELLRANMMTTNGGGLSSSQQKVLESLTALTIAQSFSQ
                     LIDDEINQIKKMYNEKKKKFGKNWEDAQKAGKAVGEDLSVNGVLNALDEGQVNESSMV
                     REPEQMISAKERQLSTIGSSVSNYIMRVRLSINEIVDKDQVLASQIGGLL"
     gene            33236..33559
                     /locus_tag="RPH49_001300"
     CDS             33236..33559
                     /locus_tag="RPH49_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124462.1"
                     /translation="MMFNQINNKNELEESYESEKKRIENELQNLNELRHRTRKENERS
                     YDVFQYLKHEMNYSEDAQRKMTRNIEAYEQEINEIIRKQEWKLEEYKEDLKKSYEKQL
                     DKLSD"
     gene            33578..33892
                     /locus_tag="RPH49_001301"
     CDS             33578..33892
                     /locus_tag="RPH49_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124463.1"
                     /translation="MTLIEPDMNLRMPDISTTVETLNLISKMEAQKENIRTVIAPEHK
                     HKYKDIENGLKGEEKVLIEQMAQHCEAFKANFKGAAQGDWVKSAMSEIDSIKDDLKKI
                     NS"
     gene            complement(34220..34480)
                     /locus_tag="RPH49_001302"
     CDS             complement(34220..34480)
                     /locus_tag="RPH49_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124464.1"
                     /translation="MSALLYNGDKDISHERESRCINMLFVILVLYVIGIAFILLSVFG
                     SKTEGLSTKHTLYTIGSAIITIAIFISIGYAIQYLTAALYGL"
     gene            34599..35801
                     /locus_tag="RPH49_001303"
     CDS             34599..35801
                     /locus_tag="RPH49_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDY5124465.1"
                     /translation="MAKIPVTVLSGYLGSGKTTLLNHILQNREGRRIAVIVNDMSEVN
                     IDKDLVADGGGLSRTDEKLVELSNGCICCTLRDDLLKEVERLVKKGGIDQIVIESTGI
                     SEPVPVAQTFSYIDDELGIDLTAICRLDTMVTVVDANRFVHDINSEDLLMDRDQSVDE
                     TDERSIADLLIDQVEFCDVLIINKIDLISEEELAKLEKVLSALQPTAKIIKTTNSEVD
                     LKEVLNTQRFDFEKASESAGWIKELESGGHASHTPETEEYGISSFVYKRRLPFHAKRF
                     NDWLESMPNNVVRSKGIIWLAQYNHVACLLSQAGSSCNIHPVTYWVASMSEAQQTQIL
                     AERQDVAAEWDPEYGDRHTQFVIIGTELDEEKLTKELDACLVNAQEIDADWQQFEDPY
                     QWQIRPAR"
BASE COUNT        13399 a         5031 c         6594 g        11174 t
ORIGIN      
        1 taacaagctt ttttaaattc tagtcagggg ccccaacaca gagaatttcg aaaagaaatt
       61 ctacaggcaa tgcaagttgg ggtgggacga cgataaagaa atactttttc tatagaaatt
      121 agtatttctt atgcatgagt tttactcatg tattcctatt tttaagtaca cattagctgt
      181 ggctaatgtg taagaaccac tacataataa attattagtg gctctttatc atttctgtcc
      241 cactccctac aggttgaata aacgtgcgaa gaaacctttt ttctcttctt gaggtttagg
      301 ttctgacatt tcagactgtg aagctgtgct gtcattttct gctttcgctt ccaatgaatc
      361 gttcgaagta gcttgtttag aagcttctgc atgggcttct gctacttgtt gttcagcatc
      421 atgttgcgct tctgcatcta ctgtagcttc tttatttgaa gtctcagctg cattgtcatt
      481 tttagactgc tcaacgctgg ctttttcaat tgcttcagtt gcagaaattt gatcctcttt
      541 atctacttta gtagtagtgc catcgcctgc attgtctgct ttagtatccg tcttagcgtc
      601 tgttgatgta ttcactccag caaccttcga atctttactg tcagcctttt catcagtagc
      661 ggacttagca tcaactttat ttgttgattc agccaatact ttagcttgag atgcttgtgc
      721 ttcttggata gcctcttgtg atgtttggat ggcttttaag gattcgctat ttgaatcgat
      781 tttagatgta agttgatttt gaagttcttt taattcttgt tgttgctgat gtacttgatt
      841 catcatttga ccaagtaggt gacgttcttc gcgcattttc tggatttcta ggcgtaaatc
      901 ttctactaat tgagcgacat tttgattagt aggtaagttt ttgtcatcgt ttttgacaat
      961 gacttgcagg aagtcttttt ctttttctaa ttcatcaaac gctagatcat aactatttgt
     1021 ttgttttact ttgtcggcaa tgtctttgaa aagctcgata tcttcttctt tgaaatcagt
     1081 tgcttcacga ccacgatatt cagtcttgct tagttggtaa ccacgttctt ctaaatgttg
     1141 aacaatttta cggacttgct tctcacttag ttctacgcgt tgtgcaaatt ctttagttaa
     1201 catactttaa agtcctttct gcatatactt tatgtatact gacgtttgtc tacgggcagt
     1261 gaaacgtcag tcttgcttca tacatagttt aaacgttatt gttagtgatt tcaagtttgt
     1321 ttaaaatggt ttacgtaaat ccatttcttc taataaagca taaataattt cacgtgcgat
     1381 accattggca aatacatact tcaaaatata atttgattta acacttgtac cgtagatatc
     1441 ctttgtcagt ttaatatttt tctttaaaaa taagtccact tttttagtgt gaccatcatt
     1501 agttggatga atgtaatcaa tttcagtttg tctttcaaat tgatgttcgt ataaaaactg
     1561 tctacggtgt tcaataatga ggccgttatc ttgtgttaaa tctgcaggtt ctttagggac
     1621 ttccatcatt aaaaagttaa tacttctaga atgaacaagg tttgataata agtttagttc
     1681 atgttcaatt tgatgtaatg tttgcgtcat taactcatca tggttgggta ggtcttttgc
     1741 gaataaataa attaaaaatg ctgaattggt tgtggcttca taatgtgcag ttgctagact
     1801 gacaacaaca tcgttttcta agcctacgat aaaaacataa tcgttttcgg ttttgttgtt
     1861 ttctaatgag cgtttgatga tacgtttatc ttcagttaaa gataaattta acttagtatc
     1921 gtaaagttta agtgcttcgt tgtaatgtgg atctttgaca gattgaatgg ttttaaattc
     1981 cataagaaca cctccccaat ttaaataata ttatagcata atcgcctgct gtaaaagact
     2041 gttcataaac ttttaaatgg tataaaaaac tgtactatct taaattagac agtacagtaa
     2101 tctcattttg aattcagtgt gataactaag ctttgggacc tttagatgct tcagcaaaat
     2161 gtgtaatatc aatctcttca taagctgaat tattttcatg cacttcttga tgtgatgatt
     2221 tgtcacgaac cgctacaact aacattttat cgtctaaaat aagttgttta tatttttcta
     2281 attcatcagg cgctaagttg tagcgtgata aaactgcatg ttcaccatct tctcctgtta
     2341 acagtttagt cattctatca ctaaatgttc cacttgttga gataagggag atttcagagt
     2401 cgtgtaagtc atttaggtgt aatttacttt tactaataat tgttagctct gattctaaat
     2461 aaccttcaga tttcttttga ttgattacgt tgtataattc gccagtgtca tttactacag
     2521 taatatctgc catagttgtc gcccctttaa aaatttgttt atttaatctt ttacccttct
     2581 tattataaag taaaaccctt acattattaa gttataagtc ttcattcgca ttaaacgtct
     2641 ctgtacattt ataaaactat taaaagatta cctaagcagt tattgaaaaa atgccgaaaa
     2701 tttgctatta tcgttaaata atttacataa actcatataa tctaaagaat atggctttag
     2761 aagtttctac catgttgcct tgaacgacat gactatgagt aacaacacaa tactaggagt
     2821 agcttcagcc attaaattgt aaccatggtg ggtgatttat atcattttat atgatggtca
     2881 cagtttattt gatgaaactt cttttacatt gattgcatga caaattcgtt atgcatgttc
     2941 gttcactcat aaaccctgaa actattattt agtttgggga tttttttgta tctagcacca
     3001 atttaagagc aaaatgtttc acacaaatct gaggaggttt taagagtgga gttactagga
     3061 caaaaagtaa aggaagacgg cgttgtcatt gatgagaaga ttttaaaagt cgatggattt
     3121 ttaaatcatc aaattgatgc aaagttaatg aatgaagttg gtcgcacttt ttacgagcaa
     3181 tttaaagata aagggattac taaaatctta accattgaag cttccggtat cgcacctgca
     3241 atcatggctg cactgcattt tgatgtgcca tgtttatttg cgaaaaaagc aaaacctagc
     3301 actttgacgg atggttatta tgaaacatct attcattcat ttactaaaaa taaaacaagt
     3361 acggtcattg tttcaaaaga atttttatca gaagaagata ctgtactcat catcgatgac
     3421 tttttagcaa atggtgatgc ttcattagga ttatacgata tcgcacagca agcgaatgct
     3481 aagacagctg gtattggtat tgttgttgaa aagagtttcc aaaatgggca tcaacgttta
     3541 gaagaagcag gtttaacagt ttcttctctc tgcaaggttg cttcactaga aggaaacaaa
     3601 gtgacattgg tgggagaaga ataatgaaaa atttaatcct aagtgttcaa catcttttag
     3661 ctatgtacgc aggtgccatc ttagttccaa tcattgttgg tacaagtttg aagtttacac
     3721 ctgaacaaat cgcttactta gttacagtag atatatttat gtgtggggtt gccacatttt
     3781 tacaagccaa taaagtaaca ggaacaggat taccaatcgt tcttggatgt acattcacgg
     3841 ctgttgcgcc catgatttta attggtcaaa cgaaaggaat agatgtactt tatggttcgc
     3901 tatttttatc agggatatta gttattatca tcgcgccttt cttttcacat cttgtaaaat
     3961 tcttcccacc agtagtaacg ggtagtgttg ttactatcat tggtatcaat ttaatgccag
     4021 tagcaatgaa ttacttagct ggaggtcaag gtgcaaagga ctatggagat gttaagaaca
     4081 ttttgttagg tttaatgaca ttaatcatta ttcttgtttt acaaagattc acaactggat
     4141 ttattaagag tattgccata ttaattggac tcgttttagg aacgataggc gctggcttac
     4201 ttgggatggt cgatattaat caagtcaatc atgccggttg gttaggcatc ccagtgccgt
     4261 ttagattctc aggatttagc tttgatgtga catcgacgtt agtgttcttt attgtagcta
     4321 tcgttagttt aattgagtcg acaggtgtct atcatgcgtt aagtgaaatt accggtaaga
     4381 agttagaaag aaaagatttt cgtaaaggtt atactgcgga aggtctagcg atagtgttag
     4441 gttctatatt caattcattt ccgtatacag cctattcgca aaatgtagga cttgtttctt
     4501 tatccggcgc taagaaaaac aatgttatat acggcatggt cgtgttattg cttatatgtg
     4561 gttgtatacc taagcttggt gcattagcaa atatcatacc gctacctgtg ttaggtggtg
     4621 cgatgatagc tatgtttggc atggtaatgg catatggtgt tagtatatta ggacatatcg
     4681 attttaaaaa tcaaaacaat ttattaatta tcgctgtatc agtaggatta ggtactggta
     4741 taagcgctgt accacaagca tttaaaggtt taggtgaaca atttgcatgg ttgactcaaa
     4801 acggaattgt tttaggcgca atctctgcaa ttattcttaa tttctttttt aatggaataa
     4861 agtataaaca aacggaagaa aatgtgaaat aatataacta attaatttga aaaatggagg
     4921 ctgtttttaa tgtgggaaag taaatttgca aaagaatcat taacgtttga tgatgtgtta
     4981 ttaattccag cacaatctga tattttaccg aaagacgttg atttaagcgt acaattatca
     5041 gacaaagtta aattgaatat tccagttatt tctgctggta tggatacagt aactgaatct
     5101 aaaatggcga ttgctatggc tcgtcaaggt ggtttaggtg ttattcataa aaatatgggc
     5161 gttgaagaac aagcggacga agttcaaaaa gtaaaacgct cagaaaatgg tgttatttca
     5221 aacccatttt tcttaacacc agaagaaagt gtttatgaag cggaagcatt aatgggtaaa
     5281 taccgtattt caggtgtacc aattgttgat aataaagaag atcgcaactt agtaggtatt
     5341 ttaacaaacc gtgacttacg ttttattgaa gacttctcga ttaaaattgt agatgtaatg
     5401 acgcaagaaa atttaattac agctccagtg aatacaacac ttgaagaagc agaaaaaatt
     5461 ctccagaaac ataaaattga aaagttacca ttagttaaag acggacgtct agaaggtctt
     5521 attactatta aagatattga aaaagttatc gaattcccta atgcagcaaa agatgaacat
     5581 ggtcgtctac ttgtagccgc agcaattggt atttcaaaag atactgatat tcgtgctcaa
     5641 aaattagtcg aagcaggtgt ggatgtctta gttatcgata cagcacatgg tcactctaaa
     5701 ggtgttatcg atcaagtgaa acatattaag aagacttacc cagaaatcac attagtagca
     5761 ggtaacgtag caactgcaga agcaacaaaa gatttatttg aagcgggtgc agatattgtt
     5821 aaagttggta ttggcccagg ttcaatttgt acgacgcgtg ttgtagcagg tgttggtgta
     5881 ccacaaatta cagcaattta tgattgtgca actgaagcac gcaaacatgg taaagctatc
     5941 attgctgatg gtggtattaa attctcagga gatatcatta aagcattagc tgctggtgga
     6001 catgcggtta tgttaggtag cttattagca ggtactgaag aaagtccagg cgcaacagaa
     6061 attttccaag gtagacaata taaagtatac cgtggtatgg gctctttagg tgcgatggaa
     6121 aaaggttcaa acgatcgtta cttccaagat gacaaagcgc ctaagaaatt tgttcctgaa
     6181 ggtatcgaag gacgtacggc ttataaaggt gcgttacaag atacaattta ccaattaatg
     6241 ggcggtgtgc gtgctggtat gggttatact ggttcacacg atttaagaga attacgcgaa
     6301 gaagcacaat ttacacgtat gggtcctgct ggtttagcag aaagccatcc acataatatt
     6361 caaattacga aagaatcacc gaactactca ttctaattaa gataaaggag aacgacaaat
     6421 atggaaatgg caaaagaaca agagttaatc cttgtcttag actttggtag ccaatacaac
     6481 caattaatta cacgccgaat tcgtgaaatg ggcgtttata gtgaattaca cgatcatgaa
     6541 atttcaattg aagaaattaa gaaaatgaat ccaaaaggta tcatcttatc aggtggtcca
     6601 aattcagttt atgaagaagg ttcatttaca attgatccgg aaatatataa tttaggaatt
     6661 ccagtacttg gtatttgtta cggcatgcaa ttaactacta aattattagg tggtaaagtt
     6721 gaacgtgcca atgaacgtga atacggtaaa gcaatcatta atgcgaagtc agatgagtta
     6781 ttcgttggct taccagcaga acaaactgtt tggatgagtc attctgataa agttattgaa
     6841 attccagaag gctttgaagt tatcgctgat agcccaagca cagactatgc agcaatcgaa
     6901 gataagaaac gtcgcattta tggtgttcaa ttccatccag aagtacgtca tacagaatat
     6961 ggtaatgatt tattaaataa ttttgtccgt cgtgtttgtg attgtaaagg tcaatggaca
     7021 atggaaaact ttatcgaaat cgaaattgaa aagattcgtc aacgcgtagg agaccgtcgt
     7081 gtattatgtg cgatgagtgg cggcgtagat tcatctgttg tagctgtact attgcataaa
     7141 gcaattggtg atcaactaac atgtatcttt gtagaccatg gcttacttcg taaaggtgaa
     7201 ggcgacatgg ttatggaaca attcggtgaa gggttcaaca tgaatattat tcgtgttaat
     7261 gcgaaagatc gttttatgaa taaattaaaa ggtgtttcag atcctgaaca aaaacgtaaa
     7321 atcattggta atgaatttgt atatgtattt gatgatgaag catcaaaact caaaggtgta
     7381 gacttccttg cgcaaggaac actatataca gacgtcatcg aatcaggtac taagacagca
     7441 caaacaatca aatcacacca caatgttggt ggattaccag aagacatgga attcgaatta
     7501 atcgaaccaa tcaatacatt gtttaaagat gaagtacgta aattaggtat tgaactaggt
     7561 attccagaac atttagtgtg gagacaacca ttcccaggac ctggtcttgg tattcgtgta
     7621 cttggagaaa ttactgaaga taaactagaa atcgttagag aatcagacgc gattttacgc
     7681 caagtgatta gagaagaagg tcttgaaaga gaaatttggc aatacttcac agtgttacca
     7741 aacattcaat cagtaggtgt tatgggagac taccgtacgt atgatcacac agtaggtatt
     7801 cgtgcagtaa catctatcga cggcatgaca agtgattttg cacgcatcga ttgggaagtc
     7861 ttacaaaaga tttcaagtcg tatcgtaaac gaagtagacc acgtcaaccg cgtagtctat
     7921 gacattacat caaaaccacc aagcacaatt gagtgggaat aattatatat agcaaatgat
     7981 aggctagaag taccgttatt acgcggtttc tagccttttt tggtgcgatt ggtatgggca
     8041 acatcatgtg atgaaatgat gggagttata tctgtagaaa ttggcgtacc aatttcttta
     8101 tgttggggct ccgcagtcaa ctactaccaa tataagattg tagagcctac gatttggatt
     8161 ttatgtcctg ggatcggttt cctattctta ttaaatagta tttaaaaatc tatactatct
     8221 atattgaaat ttttatttat ggttatgcca taactacttt gtatttccgg tactaaactt
     8281 tgcaatattg ggtaatagtt attagcgaaa ccaataataa tggaattaat cacattgata
     8341 ctaagttctt tatcttcagg taatgcattt tctattattt tgattaagtc tatatatttt
     8401 atttcatcag aatttttatg tgctaaatac ttcataaaat cagtttgcac tttttcgaaa
     8461 acactatatc ttaagtccat ttgtacaaat attaagctga cagttttagt ttcgaattga
     8521 ctttgaccca aaactgaagc aagttcttct attgattgat atagcaatct gatatcgccg
     8581 ttatcttcaa gcatatgaaa cactccttta tcattttaga ataaccatgc aatggcttct
     8641 ttgactacag ttgagattat tccagcatca cctttactta gaccggcatt tattgcgcct
     8701 cgtttaactg catcaccgac agcgttagct ggtacttctg accattttag caatggtttc
     8761 aattctttta caatacctga atacccttta tcaaaaatag ttgcagcttt tttgccgcca
     8821 acttgttgta tgacattttt tgctttgccc ctattattaa taattagctt tatagcagtt
     8881 ttaactactt ttgttccgcc aattcgttgt tgtgcttctg gattcattgg caagtttgga
     8941 ttgcgattaa ttttcacacc atttatattt tcataacttt ggtgagcagt ttttgtattg
     9001 tttgtctgta tttcatttgc gttagttaaa ggtgaaacag acgttaataa aacggcagtc
     9061 aagactagtg aaccaatagt ttttgtgatt ttcattatac atttatctcc tttaatagtg
     9121 aatttgcaaa accaaatgtt tgaaatataa gtaaataatc attaaaaaac aaagtgagtg
     9181 aaaggtccta attcgtataa ctagcattta ataatttaat taatcgtttg caccaaaata
     9241 gaaaatgcca cttaacacaa ttattaaaag taatgtaact atgaaagaag tccaagctaa
     9301 tacaagtgaa catattaaaa gtactaatga agtgactgtt tgtaagaacc caaaaagtaa
     9361 agattccatt atataagcaa aataaatagt tagtgaaaaa attgctacag caaataacat
     9421 tagccctatg attttcaaaa ttccagttgt gtagccagta actaataaat ttttcacatg
     9481 aacttgatta ccatattgtc atcccgttca taaaatagtt tagaagagat tgctattaaa
     9541 tttaattgtt ttgcataagt gtcagaatat tattcttaac tgttaagagt cgttaattta
     9601 tttaaatcca ttaaggttgt tagagattat tatgcggtga gaaacgcgac tgttacagtg
     9661 gaagatgaat ttgtataact agatatgtta atcgtaaatg tggcgtcgtg aaacacgact
     9721 tcaaacatcg aggaccaatc tatctttgag attggttgaa gattgaaaca tatgtaagaa
     9781 aatgacatag tttatggaaa ggtcgataag taattgaaaa atcaatctag attgaaatca
     9841 tgcatatcgt ttaataaaat ttttcggaga aataaaaact tactaaaaat gaaaaggttt
     9901 atttgattta tttacttgta tattgtaaaa ggttacaatg agtctataga ttatgtagag
     9961 aactctatta tgctttttga gtatatgtgg ggttctttct ttatatataa aaggagttcg
    10021 gagtggcaac actaaaagat gtaaagactg gtaaaaagga aattttgcca tcaactgcaa
    10081 aagataaaaa tggtaaaaaa gttacgttaa tttattttga aaaagacgat aaattaggtt
    10141 tttatgtgca gaaaacacaa aaagaacgtg gagtagggaa atgcgtttct ggtatagcgg
    10201 gtggcgcagt gacaggaggc actactttag gtcttgcagg tgcaggagta ggaacagtta
    10261 ctattccagt aattgggaca gttagtggag gcgtagttgg agctgttggt ggtgctgtcg
    10321 gcggtggtct aaccggtgga gccacattct gctaatagtg taggagtgat accatgaaaa
    10381 aattttttaa tatatgggta tgttcgttct tattttttag taataatatc atgggtgata
    10441 attagtataa aatttggtaa tatcagcacg acgcaaatat taatttcaaa tctgtttata
    10501 tttatcgctt atatactata tttagttaag ttcattcgtt tcaaaaaaag atgaaaatac
    10561 gttttttgcc caaaacctaa ttgtgatagc atatgaaaag tgagtagtgt ccttttttta
    10621 atctaattta cttatgaagc gaaaataacg tgcaagtaac gtgcaagtaa aaaaacgacc
    10681 taaatccctt taaaaacaag gattaggtcg tatttatttg gtaatgaatt tgtctagcga
    10741 aaataacgtg caagtaacgt gcaaataaaa aagcatgcgt aatatggtat atattttata
    10801 tgtctaggta aagtttacga acctacagat ttgaaatatt cttcagcaac tccgtctttt
    10861 ataattcttg aaataaccga ggtttttatt tttacgttgt tttgaattgt ctaaaatagt
    10921 catacataat ctgtttaaac ccttacttaa gcttgtaaaa tgcggaaata agttttcctt
    10981 ttttagttat tttttcttgg tatattttaa atccacaatt attgcaataa aattctttca
    11041 aattcttatt atcataccaa tcaacacaaa tatgtcttag tgcagtacga tcataaattt
    11101 cagaagcaat agataaggca tagtccatta caatttctcc tggtatatgc tttttgtgtt
    11161 tatcgctcct atctaattta gttattaata atgcttgaaa ttctccattc tttttagcat
    11221 cagacgagat ttttcttttc gtttttccac taacgtcttt ttcaagcttt atatttataa
    11281 tttttaagca gaagtatccc attatttcaa ggtctgattt atctataatt aaatacgtac
    11341 ggaaggaatt ttgatcgttc attgttattg ctttatgttt tagggaatgt gctattgaag
    11401 ggtttaaaga tgtttgaaat gtcttggttt cttgacttat atagttatga aagagggcgt
    11461 tgtcctttat agcatttctg agattagaaa tgctataaat aaagttatta agattttttg
    11521 ttttcatgta atttaagaaa tggatttgtt tttagtgggt tatttttaat tctgttctta
    11581 aatggtttga attttgcggt tgcaaatatg atagcagctt cttttgacaa agtaatagaa
    11641 cctttttctt ctggtaccat gatattcact ccttgtacaa ttggatttaa agtttataaa
    11701 ataattttac tatgtataat aatttgtgta aatagtttct tattgttacc gaataatttg
    11761 tttggaagcg ttatgtaatg ccaatcaaca ccaaagtcct catgtcctca ttccttttgc
    11821 gactacatat attgttaata atattgaaat tataaactga tagtgataat tttgttaact
    11881 gacccatgaa agtaggaacc ccaccatacg ggaatttcga aatcatggtt tttttgtttt
    11941 aaagtattga tgcaatagat aaagtagcca ttctaatata tggagtattt atcagctaaa
    12001 aattaaaaca gatatgaatt ttcttcatta aatcattttt ccatatagaa acagaggcaa
    12061 cgctactgtc acctctgctt gaaataatta ggttgaaata ctctgggtct aaagtccaca
    12121 cctaaatcac ccaaatcgct caaactctca accccagact aaatctccaa accccaaaac
    12181 accaatactt accaaagcat tgaaatgagt gccaatactg gcaacgtacc ttgtttgaaa
    12241 aagatactaa tattgcttga aaggccacca taaatagcaa cgccaatgat atacactaaa
    12301 atagctgcgc atatttcttt tggattactg ctgataaaca aaccgtatat tagcaaaact
    12361 ccgattaaac cattatatac gccttgattc ttcaaaagta cgttaatatt tttgtctttc
    12421 aatttatcga cgcttatatt aaatgtctcg ctagtctttt tggaagttgt agcaatcgtt
    12481 tcaaggtaca taatatagaa aaattctaat gccacaaata tgattaaaat tatcgagatg
    12541 atattcactg taacgctcct ttagtattaa atattttctt gtaaaaatga ttgtagtgtc
    12601 tgtggttgat cattgactaa ttgttggaaa tcattggatt cttggtctaa tagtcctctt
    12661 gctcctgcgt cgtacattga tgccaataat gcaccaaagc ctttaggttc atcgtacatt
    12721 tttgcaaatg tctctaatga aacgggttca tatttaattt ctgtgcctga tgcctcagat
    12781 aaaatagcag caagttcttt catatcataa ctgtagcctg ataataaata acatttgccc
    12841 caagtatctg gatttttaat aatagcaatg acgcctctag caatatcatt tctagtaata
    12901 taattaatac gaccatcacc agctggataa atcagtttat gcatattcat caattctggt
    12961 aaatatggtt taagtggatc catgtacatt gccattctta cataggtata gtcaatgcca
    13021 cttgttgcca atagacgtgc tgcataacca aaataaggac tcatatggaa tggattatta
    13081 tgctgatctg cgtaataacc tatgaaaatg atatgagcaa cgccacattg ctttgcagca
    13141 tatactaaat tttccacttc aggaatacgt ttgaatgatg gatggataat acttggaata
    13201 aacacaacgg tatccattcc tttaaatgct tctaccatgc tttcttgatt aaaataatct
    13261 aattgtcgaa cagaaacttt tccacgccaa tcttctggaa ctttctcaac atttctaaca
    13321 ccaatgtgaa aatgatctat gtgatttgca atggcttgat ttgtaatatg tgtgcctaaa
    13381 tgacctgtag cacctgttaa cataatattc attcacttca tctcctaatc tttatataca
    13441 taacataata cttattcgat ggttttcaaa acatttgatt ttataaaaaa ttgtaatctg
    13501 tatttattgt cgtcgtgtat agtaaatacg tatatgttat taatgttgaa aataccgtaa
    13561 tgacgcgttt tagttgatgt gtgtcaccat gatctttgaa atttttgaca tggtactgcg
    13621 acgatatggt gtcatttttg tgtctaaaag ttttacagtt tttaaaatta aaatggtata
    13681 aagtgtgaat tgtataaaaa agagtctcga cggataagaa ttgattaata acagttagca
    13741 ttttattaat taccttaaca atgattcaag tttagttaaa tgaggtttaa tttgaaaggg
    13801 gatagcgcct caatataatg taggtagatt gttcatatta cgtaattgaa aaatcaaatt
    13861 taaatagatt ggggctaaaa attatgaaat ttaaagcgat agcaaaagca agtttagcat
    13921 tgggaatgtt agcaacaggt gtaattacat cgaatgtaca atcagtacaa gcgaaagcag
    13981 aagttaaaca acaaagtgag gctgatttaa aactttatta tagtggacca agttttgaat
    14041 ataaaaaagt aactggatat ggatttgttg aaggtaaaga tagattcatt gattttatat
    14101 acaatggaca atataataaa atatctttag ttggttctga taaagataaa tataatgaag
    14161 aagttaatcc agatatagat gtgtttgtcg ttagagaagg aaacggtaga caagctgata
    14221 atcattcgat tggtggcgta acaaaaacta atcgaggagt gtattatgac tatatacaca
    14281 caccaatcct tgaaatcaag aaaggtaaag aagaaccaca aagtagtcta taccaaattt
    14341 ataaagaaga catttcgcta aaagaacttg attatagatt aagagaacgt gcaatcaaac
    14401 atcacggctt gtattcaaaa ggtcttaaac aaggtcaaat tacaattaca atgaatgatg
    14461 gcacaacaca tacaatcgat ttaagtcaaa aacttgaaaa agagcgtatg ggtcagtcag
    14521 tagacggcaa acaaatacaa aaaattctag tagaaatgaa ataatacttt ctaacaacaa
    14581 agcactacgc tgaatagcac ttgttttgga atatatggaa gttaagcgac gtactgttgc
    14641 ttagcttctt tttttgaggg tcaaagttac aaaactcaca caaacagtcg caccacgcat
    14701 tatcttttac ttaactagct taatcatatt ttatgaatag ttaaaaaagg gttaatgtga
    14761 atatcagaat acagctccta taatatggtt gtatgattca atttacgtaa taaaacaatc
    14821 taatctaata tattggagca tacaactatg aaaatgaaat caattgcaaa agtaagttta
    14881 gtcttgggta ttttagctac aggtgtaaat actgtaacgg aacaaccggt gcatgccgaa
    14941 aataaaccta ttcaagtaag ccaaaatagt aaaaatttaa aagcgtacta tactcaaccg
    15001 agtgttgaat ataaaaatgt gacaggttat atcagtagta ttcaacctaa agcaggtact
    15061 aaatttatga atattataga aggtaataca gttaataatc tagctttagt tggcaaagat
    15121 aagcaacact atcatacggg tgtacatcgt aaccttgata ttttttatgt taatgaggat
    15181 aagagatttg aaggttcaaa gtactctatt ggtggtatca cagaagcaag cgataaagct
    15241 gttgaccaaa tagcagaagc aagagttatt aaagaagatc atactggtga atatgattat
    15301 gactttttcc catttaaaat agataaagaa gcaatgacat tgaaagaggt cgattttaaa
    15361 ataagaaaac atcttatcga tcattatggt ctttacggtg aaatgagttc aggaacagtt
    15421 actgttaaaa tgaaatacta tggcaagtat acatttgaat tagataaaaa gttacaagaa
    15481 gaccgaatgg ccgatatcat taaagtcaca gatattgaca gaattgaagt tatagttaaa
    15541 aaagcataat gcttagactg gtcgtcgtaa tgaattgaaa ttgcaataga gaggttaagt
    15601 gatgataaaa cgttacttaa cttctttttt atgtcttaaa atcatttcaa tgatacgtag
    15661 taacaccaca taaacctcga aagtactcat tattttttgc ttaaatgact taataatact
    15721 tcaacaattg ttaaacgagg gttaatgtga atagaccaat atgtcttcta taatgaagtt
    15781 gtatgattct aattacgtaa agaacaatcg aatataatta cgattggagc atacaactat
    15841 gaaaataaga acaattgcga aagcgagttt agcgttaggg cttgtaacaa caggtgcaag
    15901 tatagtaaca acgcaatcgg ccaatgcaga agtagcatca gcacttaaag caggacagtt
    15961 agcaaagata aacgtatcat caagtgcagt cacaacgaca acgcaagcag tgaacgcaga
    16021 acaaaatcgt acggctaata ctgaacaggc atcaaagtct aatacagaaa aagtatcaac
    16081 atcgccttca attaaaacag aacagacgcc aaaatctaac acacaaaagg caactcaacc
    16141 aacaccaagc ggaacaactc agcctttacc aaatgcacaa ccgcaatcac cacaatcaac
    16201 accaaacgca tcaacatcgc cttcatctag tgtagaaaca caacaaccgc aatcgcctac
    16261 cacaaaacaa gcacaaaagg aaataaaccc taaatataag gatttaagaa catattatac
    16321 gaaaccgagt ttagaattcg aaaagcaatt tggttttatg ctgaaaccat ggacgacagt
    16381 taggtttatg aatgttatac cagattggtt catttataaa atagctttag ttggaaaaga
    16441 cgataagaaa tataaagatg ggccatacga taatattgat gtatttatcg ttttagagga
    16501 caataaatat caattaaaaa aatattctgt cgggggtatc acgaagacga atagtaaaaa
    16561 agttgatcac aaagcaagaa tcagtattac taaagaagat gagaaaggca aaatctcacg
    16621 cgatgattca gaatacaaga ttactaaaga agagatttcc ttgaaagagc ttgattttaa
    16681 attgagaaag caactcattg aacaacataa tctgtacggt aatattggtt caggaacaat
    16741 tgttattaaa acgaaaaatg gtgggaagta cacgtttgaa ttacacaaaa aattacaaga
    16801 acatcgcatg gcagatgtca tagatggcac tagtatcgac agaattgaag tgaatctaaa
    16861 atcatcgtga tggatactgc atagaaccta tgaacgatgt gccgagaagt tgagtgacaa
    16921 ctatttacat gttgctcagc ttctttcgtg ttgcgcagtg atataagaag acgaatattt
    16981 gatgttgacc acacataaca tacttatgtc ctaaatgtgt ctaaaaatcc caatctatca
    17041 agcgttgaag tacaacaaaa gtcattttta tttaacgaac attatggatt ccttaattta
    17101 attaacgatg attcaaattt agttaaacaa ggtttaatgt gaatagagtc atacgccaac
    17161 tataataaag ctgtgtgatt caataaacgt aatcgaacaa gtctaataat tacgattgga
    17221 gcatacaact atgaaaataa gaacaattgt gaaagccagt ttagctctaa gtattttagc
    17281 aactggggtt ataacatcaa cggctcaaac tgtaaatgcg agtgaacatg aagcaaaata
    17341 tgaaaatgtg acaaaagata tctttgactt aagagactac tatagtggtg aaagtaaagc
    17401 gcttaaaaat gttatcggtt atcactatag taaaggcggt agacactacc ttgtcattga
    17461 taaaaataga aagttcacaa gagtacagat atttggtaaa gatattgaaa gatttaaagc
    17521 acgcaaaaat ccgggattag acatatttgt tgttaaagaa gcggaaaacc gtaatggtac
    17581 agtttattcg tatggtggtg ttactaagaa aaatcaaggc gcctattatg attatataaa
    17641 cgcaccaaga ttccaaatca agagagatga aggtgacggt attgctacgt acggtagagt
    17701 acactacatt tataaagaag aagtatcact taaagaattg gattttaaat tgagacagta
    17761 tttaattcaa aattttgatc tgtataaaaa gtttcctaaa gacagcaaga taaaagtgat
    17821 aatgaaagat ggcggctatt atacgtttga actcaataaa aagttacaaa caaaccgcat
    17881 gagtgacgtc attgacggta gaaatattga gaaaatagaa gccaatatta gataattcaa
    17941 taaaacatgg ataatagtaa aatatggata gtatagagga gttaggcagc ataggttgct
    18001 tagcttcttt tttgtgtcgt tatgatcgga aatgaagcgg gttgatgaaa gataataacg
    18061 acaataaaac ttgtaaaaat agttgatacc tatagtcgca cggtgtcgca ttagtgacgt
    18121 gaaacaatgt ggaaaacata attaaattga aggaaagtgt taatggtgaa aaaaattagc
    18181 atagtgttat aaaaaatgat taatactgtt aggaatccat taattagctt aacgttggtt
    18241 catgaatagt taaaaagtgg ttaattcata gcgcaatatc cggcttatat aatgatagta
    18301 gattgttcgt attacgtaat tgaattaatc atataagcat atattaagtt aaattttaaa
    18361 aatagattgg gagaataata ctatgaaatt aaaaacgtta gctaaagcaa cattagcatt
    18421 aggtttatta actactggtg tcattacatc agaaggtcaa gcagtaaaag cggcagaaaa
    18481 gcaagagaga gtacaacatt tacatgatat tagagattta catcgatact actcagcacc
    18541 aagttttgaa tatagtaata ttagcggtaa ggttgaaaac tacaatggtt ctaacgttgt
    18601 acgctttaac caaaaagatc aaaatcacca attattctta ttaggaaaag ataaagaaga
    18661 atataaagaa ggtcttcaag gtcaaaatgt ctttgtagta caagaattaa ttgatccaaa
    18721 cggcagacta tctactgttg gtggtgtaac gaagaacaat aacaaaactt ctgaaactaa
    18781 aacacaatta gttgttaata aagttgatgg cggagattta catgcatcaa ttgactcatt
    18841 tttaatccaa aaagaagaaa tctcattaaa agaacttgat ttcaaaatta gacaacaatt
    18901 agttaataat tacggattat ataaaggtac atctaaatac ggtaaaatca ttatcaattt
    18961 gaaagacgaa aataaagtag aaattgattt aagtgataaa ttgcaattcg agcgcatggg
    19021 cgatgtgttg aatagtaaag acattagagg tatagcagta actattaacc aaatttaaag
    19081 taagcaatca atgactttaa agtaataaat tttgaagcag cttaacgatg aaacgttgaa
    19141 taaatacgca tatcctacaa gaggagcgtg tttaaagtaa cgccgtcgtt cggctgtttt
    19201 ttatatttaa taacgcaggt cacgagtata ctaaaaaaac caaattagac gtgaaagcta
    19261 tgtgctttga atattactta gatgttcatt aacaatgatt caaagttatt taaacgcacg
    19321 ttaatgtcag tttgtttcga tgcactttat aataaaggca gatgtttcaa attacgtaat
    19381 cataacaatc caatacatta agattggagt aaataaatat gaaattgaca gcattagcaa
    19441 aagcaacatt agcattagga atattaacta caggtgtgtt tacagcagaa agtaaagccg
    19501 ttcacgcgaa agtagaactt gatgagacac aacgcaaata ctatatctat atgttaaaag
    19561 attactattc tgaagaaagc tatgaaccaa caaacattag tgttaaaagt gaagattatt
    19621 atggttctaa cgttttaaac tttaaccatc gaaataaaaa cttcaaagta tttctacttg
    19681 gtgatgataa aaataaatat aaagaaaaaa cgcatggtct tgatgtcttt gcagtacctg
    19741 aattaataga tactaaaggt ggcatatata gcgttggcgg tataacaaag aaaaatgtga
    19801 gacccgtgtt tggctttgta agtcatccag gtttactagt taaaaaaatc gatcctaaac
    19861 atggcttttc ggtaaatgag ttgttcttta ttcaaaagga agaagtatcg ttgaaagaac
    19921 ttgattttaa aataagaaaa atgttagtcg aaaaatatag attgtataaa ggcgcgtcag
    19981 ataaaggtag aatcgttatt aatatgaaag acgaaaagaa atatgtaatt gatttaagtg
    20041 aaaaattaag ttttgatcgt atgtttgatg taatggatag taagcaaatt aaaaatattg
    20101 aagtgaattt gaattaatta agcataatag cataatagat taagaagcga cttaacaaca
    20161 aaatgtgaat tgacatgcat gtccttaaat aaggaactgt gttaaataca ttaatgttgt
    20221 taagttgttt tttgcatttc aaagtgcaga acagagtatc aacatttgtt gtagtaaaca
    20281 atgatccaga aaaacaacca catgtaaaga gtgaaagtta attaatctgg ccattaaaat
    20341 atatttgttt ttcattaata ataattcacg tatatttaaa ttgaggttaa ttatcgcatt
    20401 aaacgatgga cgttataatt agagtgtatg attcaaatta cgtaataaaa caatccaata
    20461 cattaagatt ggagtaaata aatatgaaat tgacagcatt agcaaaagca acattagcat
    20521 tagggatttt aacaacagga actttaacaa cagaggctta ttcaggtcat gctaaacaaa
    20581 atcaaaagtc agtaaacaaa catgataaag aagcattaca ccgatactac agtggaaact
    20641 ttaaggaaat gaaaaacatt aatgctttga gacatggtaa aaataactta cgttttaaat
    20701 atagaggtat gaagactcaa gtattattgc ctggagatga gtaccgtaaa tatcaacagc
    20761 gaagacatac aggcttagat gtgttttttg ttcaagaaaa aagagacaag cacgacatat
    20821 catatactgt tggtggcgta acaaagtcga ataaaacacc tgggtttgtt agtgcaccat
    20881 tattaaatgt tacaaaagaa aatggtgaag atgcttttgt gaaaggttac ccttatgata
    20941 ttaaaaaaga agaaatatca ctaaaagaat tagattttaa gttaagaaaa catctaattg
    21001 aaaaatatgg tctttataaa acaaaatcaa aagatggcaa gattaaaatt aacttgaaag
    21061 atggcagctt ttataacctt gatttaagat ctaaattaaa attcaaacat atgggggaag
    21121 tcatagatag taaacaaatt aaagatattg aagtgaattt gaagtaaata attacgaata
    21181 agaaaaatta attgaagtgg cttaacgatg aaatgtaaat tggtgtgcac accttaccaa
    21241 agggatgcat taatcgatat cgtcgttaag tcgttttttt cgttttatgg attctacccc
    21301 aatttccata aagataaaat ttccaccacc aacatcaaaa ttctcaacat cgtaacatca
    21361 ccaaatgtta taataaatct attacacaaa gagataaatt acttattcaa aggcggagga
    21421 atcacatgtc tattactgaa aaacaacgtc agcaacaagc tgaattacat aaaaaattat
    21481 ggtcgattgc gaatgattta agagggaata tggatgcgag tgaattccgt aattacattt
    21541 taggcttgat tttctatcgc ttcttatctg aaaaagcaga acaagaatat gcagatgcct
    21601 tgtcaggtga agacatcacg tatcaagaag catgggcaga cgaagaatac cgtgaagact
    21661 taaaagcaga attaattgac caagtcggtt acttcattga gccacaagat ttattcagtg
    21721 cgatgattcg tgaaattgaa acgcaagatt tcgatatcga acatttggcg acggcaattc
    21781 gtaaagttga aacatcaaca ctaggtgaag aaagtgaaaa tgactttatc ggactgttca
    21841 gcgatatgga tttgagttca acgcgtttag gtaacaatgt caaagaacgt actgcgttaa
    21901 tctctaaagt catggttaac cttgacgatt taccattcgt tcacagtgac atggaaattg
    21961 atatgttagg tgatgcatac gaatttctta tcgggcgctt tgcggcgaca gcgggtaaaa
    22021 aagcaggcga gttctataca ccacaacaag tatctaagat actggcgaag attgtcacag
    22081 acggtaaaga taaattacgt cacgtgtatg acccaacatg tggttcaggt tcactgttgt
    22141 tacgtgttgg taaagaaaca caagtgtatc gttatttcgg tcaagaacgt aacaatacca
    22201 catacaactt agcgcgtatg aatatgttat tacatgatgt gcgttatgaa aatttcgata
    22261 tccgtaatga tgatacgttg gaaaacccag cctttttagg ccatacattt gatgcggtta
    22321 ttgcgaatcc accgtatagt gcgaaatgga cagcagattc aaaatttgaa aatgacgaac
    22381 gatttagtgg ttacggcaag cttgcgccaa aatccaaagc agactttgcc tttattcaac
    22441 acatggtaca ttacctagac gatgaaggta ccatggcagt tgtgctacca catggcgtct
    22501 tattccgtgg ggctgcagaa ggtgtgattc gtcgttattt aatagaagaa aagaactacc
    22561 tagaagccgt gattggctta ccagccaata ttttctatgg gacaagtatt ccaacatgta
    22621 ttttagtatt taaaaaatgt cgccaacaag acgacaacgt attatttatc gatgcatcca
    22681 atgattttga aaaaggaaaa aatcaaaacc atttaagcga tgcccaagtc gatcgtatta
    22741 tagccacata taagcgtaaa gaaacgattg ataaatatag ctacagcgcg acattacaag
    22801 agattgccga taacgattac aacctaaata taccgagata tgtcgacaca ttctaagaag
    22861 aagagccaat tgatttagat caagtccaac aagatttgaa aaatattgac aaagaaatcg
    22921 cagaaatcga acaagaaatc aatgcatacc tgaaagaact tggggtgttg aaagatgagt
    22981 aatacacaaa agaaaaatgt gccagagttg agattcccag ggtttgaagg cgaatgggaa
    23041 gagaagaagt taggggatct tacagataga gtaattagga aaaataaaaa cttagaatcg
    23101 aaaaagcctt taacaatatc cggacagtta ggtttaattg atcaaacaga atactttagt
    23161 aaatcagttt cgtcgaaaaa tctagaaaat tatacactaa taaagaatgg agaattcgcg
    23221 tataacaaaa gttattctaa tggataccca ttaggggcta ttaaaagatt aactagatat
    23281 gatagtggtg tattgtcctc tttgtatatt tgtttttcta ttaaaagtga aatgtctaaa
    23341 gacttcatgg aagcatattt tgattcgaca cactggtata gagaagtttc tggaattgca
    23401 gttgagggtg caagaaatca cggattatta aatgtttctg tgaatgattt ttttactatt
    23461 ctaattaaat atccaagttt agaagaacag caaaaaatag gcaagttctt cagcaaactc
    23521 gaccgacaaa ttgaattaga agaacaaaag cttgaattac ttcaacaaca gaaaaaaggc
    23581 tatatgcaga aaatcttctc acaggaattg cgatttaaga atgagaatgg taatgattat
    23641 cctgattggg aaagaattaa attttttgat gtaattgata aagtaataga ttttagaggg
    23701 agaacaccaa aaaaattaaa tatggaatgg tctgacgaag ggtatttagc attatcagca
    23761 gtcaatgtaa aaaaaggcta tattgatttt aatgtagagg cgaaatatgg aaatctagat
    23821 ttatatacta gatggatgag aggaaatgaa ttatataagg ggcaagtatt atttacaact
    23881 gaagcgccaa tgggcaatgt agcacaggtt ccggataata aaggatatat attaagtcaa
    23941 agaactatcg cgtttaattc aaatgaaaaa atcactgata actttttagc atcattgttg
    24001 agctctgaaa atgtttataa tgatttatta aaattgtgta gtggtgctac agcaaaaggt
    24061 gtgagtcaaa aaaatttaaa tcgactatac gttactattc cacattccat atcagagcaa
    24121 gaagagattg ctgaattctt tagaaaaatt aatcaattgg ttgagttgca aaaatataaa
    24181 attgaacata ctaaaagtca aaaacaagtg tttttacaaa agatgtttat ttaagcattt
    24241 gagcacatct atcaattaag tattaataaa ataatcttaa attggccgat tttccttatg
    24301 taacttttag taactaaaaa tacccgattc gctatgataa aaaagcgaac attaaattta
    24361 gacactgtga aagcgcagtg tcttttttgt gtcgaaattg tgtacagaat aagtggttaa
    24421 ataaagatta agttgagata aagtgttatt cgtaaataaa agagagtaga tcgataggaa
    24481 ttgaatgata ttagttaact atttattaaa ttacttaata atgattaatt tttagttaaa
    24541 gtaagtttaa tgtgaagcac gaccattgct cattataatg aatgaggatt gttcgtattg
    24601 cgtaatagaa taaatcaaat agactaaaaa ttgggagcat agaattatga aattaaaaaa
    24661 tattgctaaa gcaagtttag cattagggat tttaacaaca gggatgatta caactactgc
    24721 tcagccagta aaagcaagta cattagaggt tagatcacaa gcgactcaag atttaaaaga
    24781 ttattataaa ggacaaagtt ttgatctgaa aaatatagga ggatataagg aaggcaacaa
    24841 ggttactttc atatatcaca atcaacaaat tgatgtgaca ctaacaggta atgaaaagtt
    24901 agaatttaat gacgatggag aaatatctaa tgttgatgta tttgtggtca gagaaaattc
    24961 tgatagatca ggtatcacaa gttctaatgg aggaataaca acttcaaata aacaagatat
    25021 catagataat gtcaaaagtg tgaacatgca aataactaaa aaaactagta gtaatactga
    25081 aactgtaact tcatcttatt acagtataag taaagagaat atctcattaa aagaacttga
    25141 tttcaaatta agaaaacact taatcgacaa aaacggtctt tataaaacag aacctaaaaa
    25201 cagcaaaatt agagttacca tggaagatgg tgggttttac acatttgaat tgaataaaaa
    25261 gttacaaaca aaccgcatgg gtgatgtaat tgatgctact aaaataaaag aaattaatgt
    25321 tgaattaaac taataatatt cgagggagta aatcatgagg gaaaatttta aattacgtaa
    25381 aatgaaagtc ggtttagtat cagttgcaat tactatgtta tatatcatga caaacggaca
    25441 agcagaagca tcagaaacta atcaaaagcc aagtacaaat caagaatcaa cagctgttac
    25501 acatactgaa caaaattcaa aagaaacaaa aacggcagag tcttctaaga actttgttaa
    25561 tttagaccct atcaaaccag gagatcaaaa ggtaacaggg actactatgc cgaatcatat
    25621 tatattactt aacatagatg gaaaaagtgt tgattcagta gatggagagg acagttcatt
    25681 tataacttca aaagaagatg ggaagtttga gtatcctcta aataatcgta aaatagttca
    25741 caaccaagaa attgaagtat catcttcatc tttagatgat ttaggtgaag atgatgaaga
    25801 ggtagaagaa gattccactg aaaaatctga agctgaagaa gaaagtacag gtgctaaagt
    25861 tacttacaca acaccgcgat atgaaaaagc gtatgaagta ccggaaaaac gattagaaga
    25921 aaaagatgga catcaccaag ttttcatcga acctattact gaaggatcag gtattattaa
    25981 agggcatacg tctgtaaaag gtaaagttgc tttatctatt aataataaat ttattaattt
    26041 tgaaacaaat tctaatggtg gcccaaataa agaagaagcg aaatctggat cagaaggaat
    26101 ctggatgcct attgatgata aaggatactt taattttgac ttcaaaacga aacgtttcga
    26161 taatttagag ttaaaagaag gtaatgacat ttcactaaca tttgcacctg atgatgaaga
    26221 tgcattaaaa cctttaattt tcaaaactaa agtaacaagt ttggaagata ttgataaagc
    26281 agaaactaaa tatgaccata ctaaagtcaa caaagtgaaa attttagata atgttaaaga
    26341 agatttacat gttgatgaaa tatatggaag cttatatcat acagacaaag gtaaaggtat
    26401 tcttgataaa gaaggtacta aagtaattaa aggaaagact aaattcgcga atgcagtagt
    26461 gaaggtagac tctgaactag gtgaagcaca attattccct gatttacaag taaatgaaaa
    26521 aggtgaattt agctttgact cacatggtgc tggttttaga ttacaaaatg gagaaaaact
    26581 aaactttaca gtagttgatc ctattacagg tgagctgttg agtaatgagt ttgtttctaa
    26641 agagattgat attgaagaaa caccagaaga aaaagcagac cgtgaatttg atgaaagact
    26701 tgaaaatacg cctgcttact acaagttata cggcgataaa atagttggtt tcgatactaa
    26761 cgatttcccg attacttggt tttatccatt aggtgaaaag aaagttgaac gtataacacc
    26821 taaattagaa aaataattaa taaaataaaa cagcttaatg atgtaatgaa attagtgagt
    26881 taatcactga cttcaacgtc attgagctgt tttttgtgct ttgttacaaa gcattattga
    26941 atttatttta cgtgttcata ttttgaaaca tcaaagccgt cttgtttagc tttgttgata
    27001 atgtctttga ttgaatgtag tcctttatcg gcgaagtatg atcttaagtt gtcttttgta
    27061 gcttggtcag cattcttatc taataacaca tcaatataac ttaattcatg ttctaagaag
    27121 tttgcatcat aatgtagtac gagtccattt tgagaataaa ctttcgcatc tgcttgatta
    27181 ccatatccaa caacgccagt tgctaaaaca cctaccattg ccgtagctac taaaaccttt
    27241 ttaaatttca tatccatcac tcctctaaaa attgtaactc catcataaca ctgaatatta
    27301 agaaaattac gtttattaag tcgatttaat gatttttaat aaatagttaa agtgacaaat
    27361 attgctaaaa agcaattaat ctctaatacg atacttatga attttcctac taaaaccttg
    27421 atttcaaaga gggtttaaat caaatgaaac aataataaaa aaatgatgca acttaataat
    27481 aagtacaaat ttaattaaga aattaaattg attgtatatg tatattttgg taacgtaaaa
    27541 gagaaatata caaaataatt aattatttat atgaaaagag aatataaatg aagtataaaa
    27601 cagagagacg tgaagcgatg ggatatttaa aaaggtttac attgtacata agtattttta
    27661 ttttaatagt tgttatagca ggttgtggta aaagtgatga aacaaaagaa gattccaaag
    27721 aagaacaaat taaaaagagc tttgcgaaaa cgttagatat gtatccaatc aaaaatctca
    27781 aggatttata cgacaaagaa ggctatagag atggcgaatt taaaaagggc gataagggta
    27841 catggacttt actcacaagt ttttcaaaaa gtaacaaacc aggcgagata gatgatgaag
    27901 gtatggtgct atatctaaat aggaatacca aaaaggcaac aggttattat tttgtaaata
    27961 aaatttatga tgatattagc aaaaatcaga atgagaaaaa ataccgtgtt gaacttaaaa
    28021 ataataagat tgttctttta gataatgtag aagacgaaaa acttaaacaa aaaattgaaa
    28081 attttaaatt ttttagtcag tatgccgatt ttaaagattt aaaaaattat caagatggaa
    28141 gtataacaac taatgaaaat gtaccgagct atgaagcaga atacaaattg aataatagtg
    28201 atgaaaatgt aaaaaaactt agagatattt atccaattac aacgaaaaag gctccaatat
    28261 taaagttaca tatagatggt gatataaaag gaagttcagt tggatacaaa aaaatagaat
    28321 ataaattttc aaaagttaaa gatcaagaga caacattaag agattattta aattttgggc
    28381 cgtctgatga agatatctaa agtttattag atatagaaat aattctaaaa cagagagacg
    28441 tgaaatgatg ggatatttaa aaaggattgg attgtgcata agcctgttga ttttaagcat
    28501 ttttgtaaca tcttgtgata gtgataataa gatcactgga gattcaaaag aagcacaaat
    28561 taaaaagagt tttgcaaaaa ctttagatat gtatccaatt aagaatctcg aggatttata
    28621 cgacaaagaa ggatatagag atggtgaatt taaaaaggga gacaaaggga cgtgggttgt
    28681 tagatctgaa atgataattc aaccaaaaag taaaagttta acttcaagag gcatgatatt
    28741 atacatgaat agaaatacta ggaccacaac tggttatttt tcaatagaag aaatagattc
    28801 aagaaaaaac cttgacgaga gagaaacaga aaaaaagtat cctgtgaaaa ttataaacaa
    28861 taaaattatt ccaaccgtaa agataaaaga tgaaaagttg aaaaaggaaa ttgaaaactt
    28921 taagtttttt gttcaatatg ggagttttaa aggaatagag aattatgaaa atggtcacat
    28981 ttcctacaat tctgaaggtc ctatttattc cgcgagatat caactgaaaa atgatgatta
    29041 taatgttaaa gaattacgaa aaagatatga tataccaaca gaaaaggcgc ccaaattatt
    29101 gttgaaaggt tcgggggatt tgaaagggtc ttcagttgga tataaggaaa ttgaatttat
    29161 atttctagaa aataaaaaag aaaatatata tttttcagat ggattaaact taattccagg
    29221 tgactaaaaa taacacaaag gttgatggtg ctcaacaaat attaacatga tagagagaag
    29281 tgaaaaaatg agggattcaa aaagagtagt attgtacata agcattatgg tgttgagtat
    29341 ttttataatt ggttgtaata gttcaagcga gaatgcaaaa aaatcaaaag aagactcaaa
    29401 agaagaccaa atcaaaaaga gttttgcgaa aacgttagat atgtatccaa ttaagaatct
    29461 cgaggatcta tatgacaaag aaggatatcg agatggcgaa tttgaaaaag gtgataaggg
    29521 gacgtggacg atatatacag attttgccaa aagtaataaa gcgggtgaat tggatagtga
    29581 aggtatggta ttacatttga atagaaatac gcggacggct aaaggatatt attttgtaag
    29641 aaaaacttat aacgaagagg ataagatgct gcaaaggaaa gattatcgta ttaaacttaa
    29701 aaataataaa attgtccttt tagataaagt agaagataaa aaactcaaac ataaaataga
    29761 aaattttaaa ttttttgggc aatatgcaga ttttaaagac ttgaaaaatt ataaaaacgg
    29821 gaaaatatcg agcaatgaaa atgttccata ttatgaagca gagtacaaaa tagaaaatag
    29881 tgatagaaat gtaaaaaaac ttagaaatgt ttatccaatt acaaccagtg aatcgccaac
    29941 tttaaaattt catatagatg gggatataaa aggtagctcg ataggatata aaaaagtgga
    30001 atatatcttt tcaaagcaaa aagataacca aatttctgtc agtgattttt taaattttaa
    30061 cccatcaaaa gataatcagt agagattcaa taaaaaatca gacaagaaag atgtggaata
    30121 atgagaaatt taaagagaga cgtattgtac ataagcatta tggctttgag tatttttata
    30181 ataggctgtg ataaatctag tgttactgct gaaaaagcaa aagaagactc aaaagaagac
    30241 caaatcaaaa agagctttgc gaaaacgtta gatatgtacc ctattaagaa tctcgaggat
    30301 ttatacgata aagaaggata ccgtgatggc gaatttaaaa agggtgataa ggggacgtgg
    30361 gttattagat ctgaaatgac aacagaacta aaagatgaaa atgtggaatc caaaggtatg
    30421 gtcgtacgtt taaatagaaa taccagaaca actacaggtg agtattttgt taggataatc
    30481 aaagaagaca atgagggcaa ggtatatagt gatgaacgaa aatacccagt caaaattgat
    30541 aataaaaaaa ttattccatt aaaattaatc gatgatgaaa aagttaaaaa agaaattgaa
    30601 gaatttaaat tctttgtaca atatgggaat tttaaagaat tggaaaacta taaagatggt
    30661 aaagtgtcat ataatccaga agtaccaatt tactctgcgc aatatcaatt gaaaaacagt
    30721 gattataatg tagagcaact acgtaagcga tataatatcc caacaagaaa ggcgcctaaa
    30781 ttgttattga aaggctcagg taatttaaaa ggatcctcag tcggatataa aaatattgaa
    30841 tttacctttg ttgaaaataa ggaagaaaat atttacttca cagatagtat taatttcaac
    30901 ccaagtgagg ataaataagt atatttagta ttataaaaaa cacgttagaa catttaataa
    30961 taaagttaaa tgaattacat gtattaaatt gaataagtta gttttgtttg ataacataaa
    31021 agtgcaataa tcactatttt attaagttgt atgaaatatt caaatgttta taaaattaaa
    31081 gcagagagat gtgaaatgat ggagtatata aaaaaaattg ctttgtacat gagtgtatta
    31141 cttttaatca tttttattgg gggatgtgga aatatgaaag aagaacagaa aaaagaagca
    31201 aatacaaata aaacagattc aaaagaagag caaatcaaaa aaagctttgc gaaaacgttg
    31261 gatatgtatc ctactgaaaa tctagaagac ttttataaca aagagggata tcgagatgga
    31321 gaatttaaaa aagatgataa aggtacttgg ctaattagat ctgaaatagt taaacagcca
    31381 aagggcaaag tgatgaaaac aagaggtatg caattatata ttaatagaaa taccaaaaca
    31441 gccaaaggtt tctttgtttt gaaagaaata agtgaaaata ataatcgtgt aaataaagat
    31501 aaggaggaaa aatacgaagt gaaaatggta ggaaataaaa ttattcctac tgaacaaatt
    31561 aatgacgaga aaataaaaaa agaaattgaa aacttcaagt tttttgtgca atatggaaag
    31621 tttaaaaatt tcgaaaaata caaaaatggt gagttttcat ataatccaga agcaccaatt
    31681 tattcggcta aatatcaatt acaaaacgac gattacaatg taaggcaact acgtaaaaaa
    31741 tatgacattt caacaaaaga agcgcctaag ttacttttaa aaggtggagg ggatttaaaa
    31801 ggttcctcag ttggtcaaaa agatattgaa tttacatttg ttgaaagaaa aggtgagaat
    31861 atttatttta atgatagtgt tgaatttata ccaagtgagg ataaataaat atgagtaaac
    31921 cagaatatca actaaaccca ggtaaaataa atgcaaatac agaagaaaca tctgctatat
    31981 cctattttag ttatcaaatt gaaaatgcaa atattagtgg tttggataaa gtaaaaatgt
    32041 atcagcaaat tgatatacta aaagatagat acaaattccc ttctaatctt gaatatgttg
    32101 atagttacac tgattctctt actggagtaa caacttctgc ttttttaaat aaagatacag
    32161 gcaaagtaac tctcgggatg actgggacta atttacaaga cgaagccttt aaaaagttaa
    32221 aagaaggtga attttcaaga caaaatttta ccaatgcttt ggaaacagtt aaagatggat
    32281 atgcagatct taaaatatta tattctcctg catctgatca aaactataga tatgcgaata
    32341 cacaagaatt tataaataaa ataaaaagta agtatgacat tgattttatt actggtcatt
    32401 cactaggtgg aagagatgca gtagttctag gaatgagtaa tggtattccg aacattgtgg
    32461 tttataatcc agctcctatt tctataacta gtttgaatcc taattcccca gatggaaaac
    32521 gattgttaga gttatataaa aattataaag gtaatattac taggtttgtt gcagaaaatg
    32581 atgcattgac agaaaatctg aagaaatata agcattatgt ttttttcggt aatgataaag
    32641 tctttaaaaa tggtaaaggt catggaatgg aaggctttct gaccaaagaa gaacaaaaag
    32701 ctataaaaaa agaactaaaa aaactacaag gttatgcaga agaaaataat aagtcatttg
    32761 taaagcattc aaataatgct atctctaaat tagctagtat agaattactt agagcaaata
    32821 tgatgactac aaatggagga ggattatctt cttcgcagca aaaagtttta gaaagtttaa
    32881 cagctttaac aattgcgcag tcattcagtc aactgataga cgatgaaatt aatcaaatca
    32941 aaaaaatgta taatgaaaag aaaaagaaat ttggaaaaaa ttgggaagac gctcaaaaag
    33001 ctggaaaagc tgtaggtgaa gatttgagtg taaatggagt tctcaatgct ttagatgaag
    33061 gtcaagtgaa tgaaagtagt atggtaagag aacctgaaca aatgatatct gcaaaagaaa
    33121 gacaactttc aacgataggg tcttctgtat caaattatat tatgagagtt agactcagta
    33181 ttaatgaaat cgttgataaa gatcaagtgc ttgcatcaca aataggtgga ttactatgat
    33241 gtttaatcaa attaataata aaaatgaatt agaagaatca tatgaatctg agaaaaaacg
    33301 tatagagaat gaactgcaaa atttaaatga acttaggcat agaactcgaa aagaaaatga
    33361 acgtagttat gatgtttttc aatatttgaa gcacgaaatg aattatagtg aagatgccca
    33421 aaggaaaatg acgagaaata tagaagcgta tgagcaagaa atcaatgaga taattagaaa
    33481 gcaagaatgg aaattagaag aatataaaga agacttaaaa aagtcttatg aaaagcagtt
    33541 agataaacta agtgactgat aatttggagg agattaaatg actctaatag aaccagatat
    33601 gaacttaaga atgccagata taagtactac agtagaaaca cttaatctca tatctaaaat
    33661 ggaagcgcaa aaagaaaata ttcgcacagt tattgcacct gaacataagc ataaatataa
    33721 agatattgaa aatgggttaa aaggtgaaga aaaagtatta attgaacaaa tggcgcagca
    33781 ttgcgaagct tttaaagcta attttaaagg cgcagctcaa ggagattggg ttaaaagtgc
    33841 tatgtctgag attgacagca ttaaggatga cctgaaaaaa attaatagct aaactacata
    33901 tcatattaat aaataaagct cccttcaaaa ttttcatttt ttcaatgtct actttggagg
    33961 gagcgcttca gtatattcac aactgacact aggccgcttc tttttaattt attttattcc
    34021 catgtaaagt aattcgaacc gaatggacat accacactca caattgtaaa aacacaactt
    34081 aaattactgt cccgcattaa acatatccac attccaaaca gcaacaacaa aatcctcaag
    34141 taccaaaagc tatgaccact ttatcaaaat caacgcaagt caacatcgac cgaactactt
    34201 gccattaatc atcctcacct tacaaaccat aaagcgctgc agttaagtat tgaatggcat
    34261 agccaattga aatgaaaata gcaatcgtta taatagcact gccaatggta tataacgtat
    34321 gtttcgtaga taatccttca gtctttgaac caaaaacact gagtagaata aatgcaatac
    34381 caatgacata taaaactaaa atgacaaata gcatgtttat acacctcgat tctctttcgt
    34441 gagatatatc tttgtctcca ttataaagta aagcgctcaa taatttaatt aagtatacta
    34501 tttttttatt atcgaagatt gcgaaagatg aaacgctcct atataatgta aaacggaatt
    34561 attcctattt acaaataaat tgaagtgagg gtatatatat ggctaaaatt ccagttacgg
    34621 tattaagtgg ttatttaggc tcggggaaaa caacattgtt aaatcatatt ttacaaaatc
    34681 gtgaaggtcg acgtatcgcg gtaattgtaa atgatatgag tgaagttaat atcgataaag
    34741 atcttgtcgc agatggtggg ggactatcgc gtacagatga aaaattagtc gaactctcta
    34801 atggttgtat ctgttgtaca cttagagatg atttattaaa agaagttgag cgtttagtga
    34861 aaaaaggtgg catcgatcaa attgttattg agtcaacagg gatttcagag ccagtacctg
    34921 ttgcacaaac tttctcatat attgatgatg aacttggcat tgatcttaca gcgatttgcc
    34981 gtttagatac aatggttaca gttgttgatg ctaaccgctt cgtacatgac atcaactcag
    35041 aagatttatt gatggatcgt gatcaaagcg ttgatgaaac agatgaacgt tcgattgctg
    35101 atttattaat tgaccaagtt gaattttgtg atgtattgat tattaataaa attgatttaa
    35161 ttagtgaaga agaacttgca aagttagaaa aagtgttaag cgcattgcaa cctactgcta
    35221 aaattattaa gacaacaaat tctgaagtag atttaaaaga agtcttaaat acgcagcgtt
    35281 ttgattttga aaaagcgagc gagtcagcag gatggatcaa agaacttgag tctggtgggc
    35341 atgcatcgca tacacctgaa acagaagaat atggtatatc atcgtttgta tataaacgtc
    35401 gacttccttt ccatgctaaa aggttcaatg attggttaga aagcatgcca aataatgtcg
    35461 ttcgatcaaa aggtatcata tggctagcac aatacaatca cgtagcatgt ttattatctc
    35521 aagcagggtc atcttgcaat attcatccag ttacatattg ggtggctagt atgtctgaag
    35581 cgcaacaaac acaaatatta gcagaacgtc aagatgtcgc agctgaatgg gatccagaat
    35641 atggcgatcg tcatacacaa tttgtcatta ttggtacaga attagatgaa gaaaaattaa
    35701 caaaagaact cgacgcatgc ttagtcaatg cgcaagaaat tgatgcagat tggcaacaat
    35761 ttgaagatcc atatcaatgg caaattagac cagcacgata agttgaatga agtataatca
    35821 tttttaaatt gtggcttaat tgtttgcaat ttatgacaat taataaaaag ttaaggtgtt
    35881 cttaggatct ttttgttttc aatctattta aagtgtgata gttttgataa agcagaaatt
    35941 tgcattttat ccatagggct aggacatgta tgtgtcttag tcctttttat gtttgctttg
    36001 atgaaaaatg gcaaaaccat cgtaccaact gttaattgaa ggtacaatca ttgtttaaca
    36061 gtcataaaaa tgagtgaagt aaatgcagct atcaatgtac tattaacact tacggtcaca
    36121 cgagtgtttc agtctaaacg tgcaacgcaa ttccgcacgt ggccaatata tcttgcgcta
    36181 gatcatgaaa atcattaa
//
LOCUS       DAPSKH010000026        35859 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPSKH010000026 DAPSKH010000000
VERSION     DAPSKH010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 35859)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35859)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35859
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.026"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..361
                     /locus_tag="RPH49_001304"
     CDS             <1..361
                     /locus_tag="RPH49_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF3885 domain-containing protein"
                     /protein_id="HDY5124466.1"
                     /translation="VIRKFTSLTIDELYYFKEYKKEKDDNILCEEFSYKCSIKDIKYK
                     KLLKAISNQDFKGLVPNINQNDNYSEIYIINNTKNVIYHLYDDRGLWLAFNNNEDYAR
                     YSEKYNDLISEFDNEDI"
     gene            complement(412..615)
                     /locus_tag="RPH49_001305"
                     /pseudo
     CDS             complement(412..615)
                     /locus_tag="RPH49_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001789088.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(652..1392)
                     /locus_tag="RPH49_001306"
     CDS             complement(652..1392)
                     /locus_tag="RPH49_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDY5124467.1"
                     /translation="MFNLENDLETLKHIIDSSNRITFFTGAGVSVASGVPDFRSMGGL
                     FDEISKDGLSPEYLLSRDYLEDDPEGFINFCHKRLLFVDTKPNIVHDWIAKLERNQQS
                     LGVITQNIDGLHSDAGSQHVDELHGTLNRFYCNACHKSYTKSDVIDRTLKHCDNCGGA
                     IRPDIVLYGEMLDQPTIIRALNKIEHADTLVVLGSSLVVQPAAGLISNFKGDNLIIIN
                     KDRTPYDSDATLVIHDDMVSVVKSLITG"
     gene            1598..2389
                     /locus_tag="RPH49_001307"
     CDS             1598..2389
                     /locus_tag="RPH49_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDY5124468.1"
                     /translation="MTHRLNKGGNFTLNKHERLDEIAKLVNKKGTIRTNEIVEGLNVS
                     DMTVRRDLIELENKGILTKIHGGARSNSTFQYKEISHKEKHTRQIAEKRFIARKAASL
                     IEDGDTLFFGPGTTVELLAEEVNHHTLTIITNCLPVYKILLEKQTAHFRVYLIGGEMR
                     HITEAFVGEMANAMLEKLRFSKMFFSSNAVNKGAVMTSTLDEAYTQQLALSNSIEKYL
                     LIDHTKVGKEDFTSFCQLNELTAVVMDYEDEEKVETIKTYIEVVD"
     gene            2757..3185
                     /gene="lacA"
                     /locus_tag="RPH49_001308"
     CDS             2757..3185
                     /gene="lacA"
                     /locus_tag="RPH49_001308"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HDY5124469.1"
                     /translation="MAIIIGSDEAGKRLKEVIKSYLLDNKYDVVDVTEGQEVDFVDAT
                     LAVAKDVQSQEGNLGIVIDAFGAGSFMVATKIKGMIAAEVSDERSGYMTRGHNNSRMI
                     TMGSEIVGDTLAKNVVKGFVEGKYDGGRHQIRVDMLNKMC"
     gene            3201..3716
                     /gene="lacB"
                     /locus_tag="RPH49_001309"
     CDS             3201..3716
                     /gene="lacB"
                     /locus_tag="RPH49_001309"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HDY5124470.1"
                     /translation="MKIALGCDHIVTDTKMRVSEFLKSKGHEVIDVGTYDFTRTHYPI
                     FGKKVGEQVVSGNADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSALYAKEELNAN
                     VIGFGGRIIGELLMCDIIDAFINAEYKPTEENKKLIAKIKHLETSNADQADPHFFDEF
                     LEKWDRGEYHD"
     gene            3729..4661
                     /gene="lacC"
                     /locus_tag="RPH49_001310"
     CDS             3729..4661
                     /gene="lacC"
                     /locus_tag="RPH49_001310"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HDY5124471.1"
                     /translation="MILTLTLNPSVDISYPLTALKLDDVNRVQEVSKTAGGKGLNVTR
                     VLAQVGEPVLASGFIGGELGQFIAKKLDHAGIKHAFYNIKGETRNCIAILHEGQQTEI
                     LEQGPEIDNQEAAGFIKHFEQLLEKVEAVAISGSLPKGLNQDYYAQIIERCQNKGVPV
                     ILDCSGATLQTVLENPYKPTVIKPNISELYQLLNQPLDESLESLKQAVSQPLFEGIEW
                     IIVSLGEQGAFAKHNHTFYRVNIPIISVLNPVGSGDSTVAGITSAILNHENDHDLLKK
                     ANTLGMLNAQEAQTGYVNLNNYDDLFNQIEVLEV"
     gene            4665..5645
                     /gene="lacD"
                     /locus_tag="RPH49_001311"
     CDS             4665..5645
                     /gene="lacD"
                     /locus_tag="RPH49_001311"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDY5124472.1"
                     /translation="MSKSNQKIASIEQLSNNEGIISALAFDQRGALKRMMAKHQTEEP
                     TVAQIEQLKVLVAEELTQYASSILLDPEYGLPASDARNKDCGLLLAYEKTGYDVNAKG
                     RLPDCLVEWSAKRLKEQGANAVKFLLYYDVDDTEEINIQKKAYIERIGSECVAEDIPF
                     FLEVLTYDDNIPDNGSVEFAKVKPRKVNEAMKLFSEPRFNVDVLKVEVPVNMKYVEGF
                     AEGEVVYTKEEAAQHFKDQDAATHLPYIYLSAGVSAELFQETLKFAHEAGAKFNGVLC
                     GRATWSGAVQVYIEQGEDAAREWLRTTGFKNIDDLNKVLKDTATSWKQRK"
     gene            5667..5978
                     /locus_tag="RPH49_001312"
     CDS             5667..5978
                     /locus_tag="RPH49_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDY5124473.1"
                     /translation="MNREEVQLLGFEIVAFAGDARSKFLEALTAAQAGDFAKADALIE
                     EGNNCIAEAHRAQTSLLAKEAQGDDIAYSVTMMHGQDHLMTTILLKDLMKHLLEFYKR
                     G"
     gene            5984..7696
                     /locus_tag="RPH49_001313"
     CDS             5984..7696
                     /locus_tag="RPH49_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDY5124474.1"
                     /translation="MMQKLIAQIEKGKPFFEKLSRNIYLRAIRDGFISAMPVILFSSI
                     FLLIAYVPNIFGFKWDKGMEAILMKPYNYTMGLVAFLVAGTTAKSLTDSFNRKLESTN
                     QINFISTMLAAMCGFLFLASDPAKDGGFLSAFMGTKGLLTAFLSAFVTVIVYNFCVKR
                     NITIKMPKEVPPNISQVFKDLIPFSAVIIILYALDLVIRNSFKSNVAEGILKLFEPLF
                     TAADGWIGVTIIFGAFALFWFVGIHGPSIVEPAIAAITYANIEANFKLLQAGEHADKI
                     ITSGTQMFIVTFGGTGATLVVPFMFMWMTKSKRNKAIGRASVVPTFFGVNEPILFGAP
                     LVLNPVFFIPFVLAPIVNVWIFKLFVEVLGMNSFSVNLPWTTPGPLGIIMGTGFGLWS
                     FVLAITLIVVDIIIYYPFLKVYDSEILDEEEGRKESNSDLKEKVAANFDTKKADSILA
                     ASGVSDDAAKASNITEQTNVLVLCAGGGTSGLLANALNKAAEEYHVPVKAAAGGYGAH
                     MDIMKEYQLIILAPQVASNYEDIKQDTDRLGIKLAKTQGAEYIKLTRDGQAALDFVQQ
                     QFEN"
     gene            7714..9126
                     /gene="lacG"
                     /locus_tag="RPH49_001314"
     CDS             7714..9126
                     /gene="lacG"
                     /locus_tag="RPH49_001314"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDY5124475.1"
                     /translation="MTKTLPEDFIFGGATAAYQAEGATNTDGKGRVAWDTYLEENYWY
                     TAEPASDFYNRYPVDLELSEKFGVNGIRISIAWSRIFPNGYGEVNPKGVEYYHKLFAE
                     CHKRHVEPFVTLHHFDTPEVLHKDGDFLNRKTIDYFVDYAEFCFKEFPEVKYWTTFNE
                     IGPIGDGQYLVGKFPPGIKYDFEKVFQSHHNMMVAHARAVKLFKDGGYQGEIGVVHAL
                     PTKYPFDPSNPEDVRAAELEDIIHNKFILDATYLGKYSRETMEGVQHILSVNGGKLNI
                     TDEDYAILDAAKDLNDFLGINYYMSDWMRGYDGESEITHNATGDKGGSKYQLKGVGQR
                     EFDVDVPRTDWDWMIYPQGLYDQIMRVVKDYPNYHKIYITENGLGYKDEFIESEKTVH
                     DDARIDYVRQHLNVIADAIKDGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQE
                     RYPKKSAYWYKELAETKEIK"
     gene            9392..10261
                     /locus_tag="RPH49_001315"
     CDS             9392..10261
                     /locus_tag="RPH49_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5124476.1"
                     /translation="MKKIFVIITTLLAVAIIIGSIITVVFSQRQAQTFKIQQQQFVKK
                     PIPTLFLHGFGGSANSEKFMVKQAEKRGVTKDIITAYVSKDGAVTFKGKLRKDAVNPI
                     VKIELENNRQGYLDKNAAWFKNVLTKLQSEYNFDKFNFVGHSMGNLTFAQYMMTYGND
                     KSLPQLNKQVNIAGTFNGVLNMNEDVNEITVDKDGKPSRMNQPYQQLRVLKDIYKGKG
                     IEVLNIYGDLKDGTHSDGRVSNSSSKSLKYLLGNSPKSYRESKYEGEPAQHSQLHENE
                     NVANELIDFLWKK"
     gene            10544..11545
                     /locus_tag="RPH49_001316"
     CDS             10544..11545
                     /locus_tag="RPH49_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDY5124477.1"
                     /translation="MQNKQILFNKIPEGMPQEDTFKIEEIDTPKLESDGVLVQTLYIS
                     VDPYMRGRMTKADSYVQPFEIGKPIVSHVVAKVIDSTLADYKKGDVVVGMLPWRIINH
                     VQADQITKVPTTDVPLDLYLSVLGMPGQTAYHGLLDIGQPKAGDTVVVSAASGAVGSV
                     VGQIAKIKGCRVVGIAGGDKKVNYLTETLGFDAGIDYKKEDFAEALAQAVPDGIDVYF
                     ENVGGTVGDEVFKHLNRFARVPVCGAISSYNHPEADIGPRIQGTLIKKQVMMRGFLVS
                     EFANAFKEASEQLATWVQEGKIQSQVTIEDGFENAPHAFKNLFTGDNFGKQVIKVTE"
     gene            11779..12786
                     /locus_tag="RPH49_001317"
     CDS             11779..12786
                     /locus_tag="RPH49_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDY5124478.1"
                     /translation="MKMIGFEKPFKLEEGNLFKVYEQRKPTPENDDILVKVNSISVNP
                     VDTKQRQMEVTQAPRVLGFDAIGTVEAIGPDVTLFSPGDVVFYAGSPNRQGSNATYQL
                     VSEAIVAKAPHNISANEAVSLPLTGITAYETFFDTFKISHNPSENVGKSVLIINGAGG
                     VGSIATQIAKRYGLTVITTASRQETTEWCEKMGADIVLNHKEDLVRQFKEKEIPLVDY
                     IFCTYNTDLYYNTMIELIKPLGHITTIVAFNEDQDLNALKLKSITFTHEFMFARPIHR
                     TPDMIKQHEYLEDITKNIESGHYQPTTTQVFEGLSPENLYQAHLLLEKQSMIGKLVIN
                     I"
     gene            13093..14655
                     /locus_tag="RPH49_001318"
     CDS             13093..14655
                     /locus_tag="RPH49_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDY5124479.1"
                     /translation="MKNKSVSLVFWVSLVICTIFVAFGAIFPKQLEKLTQNITTFIAL
                     HFSWYYLLLVLVILFVCVYILFSRYANITLGEEGEDPEFSLPSWFAMLFSAGMGIGLV
                     FWTTAEPISHAFKLTPIHKAGTQSAINDAMQFSFFHWGIHAWAVYGIVALVFAYFSFH
                     KGYPGLVSATLTPLLGEKAMRGPLGGAIDVLAVIATVTGVAATLGFGALQINEGLHFL
                     FNVPSNFTMQVILIVITTILFTWSAWSGIDKGIKTLSNINMLLAFVVLIGLFIVGPTL
                     YILNTFTNGLGNYIANFFSMSLRIPSGGQKFQWLQNWTIFYWAWWISWAPFVGIFIAR
                     VSKGRTIKEFILGVLFVPALVCFIFFAVFGASAIYLQDNHIADIAKAATETATFATLQ
                     HYPLGFVLSLITLLVIMIFFVTSADSATYVLGMLSSRGDINPKSFVKVSWGIIMALFA
                     IIMIYTGGTQAIQNLLIIAALPFSVVIIAMIWSLLKSLSEEKPRNSNKVLIKHRDPDI
                     LEYRSSKHIDEN"
     gene            14830..15366
                     /gene="amaP"
                     /locus_tag="RPH49_001319"
     CDS             14830..15366
                     /gene="amaP"
                     /locus_tag="RPH49_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDY5124480.1"
                     /translation="MKRLKNFILGLLIVVIVGFLLFMYIQDGRITEYQDYFLQFEWFQ
                     PLLISLAALLILIGLILVFSIFKPTHRKPGLYKDFDDGHVYVSRKAVEKTAFDTVAKY
                     DQVRQPNVVAKLYNKKNKSYIDIKTDFFVPNNVQVQSLTEAIRSDIKKNVEYFTEMPV
                     RKLEVNVRDQKTSGPRVL"
     gene            15379..15618
                     /locus_tag="RPH49_001320"
     CDS             15379..15618
                     /locus_tag="RPH49_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDY5124481.1"
                     /translation="MANNHNQNGQDSTQQVINFLKVFKWRIVGFLAFLLIAILFLTLG
                     FWKTILIIVLCLIGVGIGYMKDRKQDFMNFLNRWS"
     gene            15681..16190
                     /locus_tag="RPH49_001321"
     CDS             15681..16190
                     /locus_tag="RPH49_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDY5124482.1"
                     /translation="MTVDNNKAKQAYDNQTGVNEKEREERQKQQEQNQEPQFKNKLTF
                     SDEVVEKIAGIAAREVKGILDMKGGLTDTFTNAFSSGNNVTQGVSVEVGEKQAAVDLK
                     VILEYGESAPKIFRKVTELVKEQVKYITGLDVVEVNMQVDDVMTQKEWKQKHEKNNEN
                     NNQERQGLQ"
     gene            complement(16351..18327)
                     /gene="sfaD"
                     /locus_tag="RPH49_001322"
                     /gene_synonym="sfnaD"
     CDS             complement(16351..18327)
                     /gene="sfaD"
                     /locus_tag="RPH49_001322"
                     /gene_synonym="sfnaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ornithine--citrate ligase SfaD"
                     /protein_id="HDY5124483.1"
                     /translation="MNLNLIFKEQTLKFNKEEQETYLFLQQHNNDWANIFKEMILQGR
                     DKVTQRLVTSMHRENLVKARTQSKKILSRDLIMLDISTTHILEIQFPQAKQTLYAPIT
                     GEHAFDRIDVEGPFYIKDDITNTITRVHHPNEILECILIEAPDLKNAASDQFQQDLIN
                     SATNMTFAISYQALSMQHDSTPLFNIIENSEDSYLRSEQAVIEGHPLHPGAKLRKGLN
                     ALQTFLYSSEFNQPIKLKIVLIHSKLSRTMSLSKDYDTTVHQLFPDLIKQLENEFTPK
                     FNFNDYHIMIVHPWQLDDVLHSDYQAEVDKELIIEAKHTLDYYAGLSFRTLVPKYPAM
                     SPHIKLSTNVHITGEIRTLSEQTTHNGPLMTRILNDILEKDVIFKSYASTIIDEVAGI
                     HFYNEQDEADYQTERSEQLGTLFRKNIYQMIPQEVTPMIPSSLVATYPFNNESPVVTL
                     IKRYQSAASLSDFESSAKSWIETYSKALLGLVIPLVTKYGIALEAHLQNAIATFRKDG
                     LLDTMYIRDFEGLRIDKAQLNEMGYSTSHFHEKSRILTDSKTSVFNKAFYSTVQNHLG
                     ELILTISKASNDSNLERHMWYIVRDVLDNIFDQLVLSTHKSNQVNENRINEIKDTMFA
                     PFIDYKCVTTMRLEDEAHHYTYIKVNNPLYRENN"
     gene            18429..19622
                     /gene="sfaA"
                     /locus_tag="RPH49_001323"
     CDS             18429..19622
                     /gene="sfaA"
                     /locus_tag="RPH49_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A export MFS transporter"
                     /protein_id="HDY5124484.1"
                     /translation="MTKYFFSSSFLLFLGNWIGQIGLNWFVLTTYHNAVYLGIVNFCR
                     LVPILLLSVWAGAIADKYDKGRLLRITISSSFLVTAILCVLTYSFTAIPISIIIIYAT
                     LRGILSAVETPLRQAILPDLSDKISTTQAVSFHSFIINICRSIGPAIAGVILAVYHAP
                     TTFLAQAICYFIAVLLCLPLHFKVTKMPEDATRYMPLKVIIDYFKLHMEGRQIFITSL
                     LIMATGFSYTTLLPVLTNKVFPGKSEIFGIAMTMCAIGGIIATLVLPKVLKYIGMVNM
                     YYLSSFLFGIALLGVVFHNIVIMFICITLIGLFSQWARTTNRVYFQNNVKDYERGKVL
                     SIIMMDRGMIPLGSLLMSICADVFGIVRTFSIMGISTICITMVFYFINRKLKLKLEES
                     NHGIS"
     gene            19609..21366
                     /gene="sfaB"
                     /locus_tag="RPH49_001324"
     CDS             19609..21366
                     /gene="sfaB"
                     /locus_tag="RPH49_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A synthetase SfaB"
                     /protein_id="HDY5124485.1"
                     /translation="MVYLEWAKADRNIQYRVINAIIKERIYPEQTFISQKGSLIEIQY
                     HMHVLTIEVVRKSALERYEFTGDITYLNKGETSLIITLEGLLDVLNHDFDIPISERLR
                     EELIHSRDSLVETYKQMSHRQTLISQSFKFSRLPQDINFFSWLQHVKDSDKTDDLTYS
                     ESLVPEGHPTHPLTKTKLPLTMEEVRAYAPEFEKEIPLQIMMIEKDHVVCTAMDGNDQ
                     FIIDEIIPEYYNQIRVFLKSLGLKSEDYRAILVHPWQYDHTIGKYFEAWIAKKILIPT
                     PFTILSKATLSFRTMSLIDKPYHVKLPVDVQATSAVRTVSTVTTVDGPKLSYALQNML
                     NQYPGFKVAMEPFGEYANVDKDMARQLACIIRQKPEIDGKGATVVSASLVNKNPIDQK
                     VIVDSYLEWLNQGITKESITTFIERYSQALIPPLIAFIQNYGIALEAHMQNTVVNLGP
                     HFDIQFLVRDLGGSRIDLETLQHRVSDIKITNDSLIADSIDAVIAKFQHAVIQNQMAE
                     LIHHFNQYDCVEETELFNIVQQVVAHAINPTLPHANELKDILFGPTITVKALLNMRME
                     NKVKQYLNIELDNPIKKEV"
     gene            21373..22443
                     /gene="sfaC"
                     /locus_tag="RPH49_001325"
     CDS             21373..22443
                     /gene="sfaC"
                     /locus_tag="RPH49_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin A biosynthesis protein SfaC"
                     /protein_id="HDY5124486.1"
                     /translation="MAHVNINISKIKYNAKVLQTVFQSKNMQFTPVIKCIAGDRTIVE
                     SLKALGINHVAESRLDNIISIADQDLTYTLLRTPAKKEISDMIEKVDMSIQTELSTIH
                     QINEVAEVLGKKHKILLMIDWKDGREGVLTYDVLDYIKEIIHLKNIHFVGLAFNFMCF
                     KSDAPSDDDIFMINRFVSAVEREIGYRLKIISGGNSSMLPQLLYNDLGKINELRIGET
                     LFRGVDTTTNQAIAMLYQDAITLEAEILEIKPRVNTQTHESFLQAIVDIGYLDTKVDN
                     ISPMDQHINILGASSDHLMLDLNGQGHYQVGDHISFSLNYEALSHSMYMKNLHKVYID
                     DSKIDTLLQNFDVKSPAMVNQY"
     gene            complement(22544..22669)
                     /locus_tag="RPH49_001326"
     CDS             complement(22544..22669)
                     /locus_tag="RPH49_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124487.1"
                     /translation="MYHGYIIFALMQLTPFSMTVIPVIQLILSVAILCDELLHFI"
     gene            22836..23819
                     /locus_tag="RPH49_001327"
     CDS             22836..23819
                     /locus_tag="RPH49_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDY5124488.1"
                     /translation="MRGLKTFSILGLIVALFLVAACGNTDNSSKKESSTKDTISVKDE
                     NGTVKVPKDAKRIVVLEYSFADALAALDVKPVGIADDGKKKRIIKPVREKIGDYTSVG
                     TRKQPNLEEISKLKPDLIIADSSRHKGINKELNKIAPTLSLKSFDGDYKQNIDAFKTI
                     AKALDKEKEGEKRLAEHDKLINKYKDEIKFDRNQKVLPAVVAKAGLLAHPNYSYVGQF
                     LNELGFKNALSDDVTKGLSKYLKGPYLQLDTEHLADLNPERMIIMTDHAKKDSAEFKK
                     LQEDATWKKLNAVKNNRVDIVDRDVWARSRGLISSEEMAKELVELSKKEQK"
     gene            23831..24862
                     /locus_tag="RPH49_001328"
     CDS             23831..24862
                     /locus_tag="RPH49_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDY5124489.1"
                     /translation="MAIKEISSQSAIDHKRKRRTTLTYIVSLCFLFICIYLNMAIGSS
                     KINFSDIVHYVTGHTDTKATFLLHNVRMPRMIAGLFIGGALAVSGLLMQAMTRNPLAS
                     PKIFGVSSGASFVIVLVTIIIPSLEYYALYLGVIGAFIGGLTVYTLSGATKGMTPIKL
                     ALAGMAIHLFFSSMTEGIIILNENSNEQVMFWLVGSLSSMKWDEILTILPWLIGALIA
                     TVFIGRQLTIMELGDDIAKGLGQNINKVRIIIGLLVIILTGMSVSVAGPIGFVGLIVP
                     HIVKRYVSKNYLVMIPLTFIIGADLLLLSDVLSRLITYPYESPVGIVTSFVGALYFLF
                     ITIKGVKRI"
     gene            24859..25827
                     /locus_tag="RPH49_001329"
     CDS             24859..25827
                     /locus_tag="RPH49_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDY5124490.1"
                     /translation="MMTTKIIRRYSLITILLIVSIFISLCVGSVMIHPIDAIKGIFAQ
                     DDFILNEYRIPRTLLGIIIGSSLAISGAIIQAVIRNPLASPDVIGISKGASLAAVIII
                     MIFPTAPLFVLPIGSFLGAFAVSLFLSFLISKYDVKGSKLALIGLAIGAICTAIVQFL
                     LIRNPLEANKALVWLTGSLYGHDMSNIYTILPWFLITIPIIILLSYQLDVLNLGDAVA
                     TALGLKVKTIKMLLLILAVILAGSAISVVGGISFLGLIAPHIARQLIGNKTLHVIIMS
                     GLIGAILLTFGDGLARGIHPPLDIPVGVIIAIIGAPYFLILLRRMK"
     gene            26063..27433
                     /locus_tag="RPH49_001330"
     CDS             26063..27433
                     /locus_tag="RPH49_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiH family protein"
                     /protein_id="HDY5124491.1"
                     /translation="MDSFSRKEIVIGRLKFITMSLIGILLFLVPIPVEQDGQKQTTLP
                     VAFLAGVLKDVLGGVMPFLIVTIITLSGIITLICSTILKDKLKPDGLMNNAFNVRIGW
                     LILRLLAVVFAWMTFLRIGSKVIYSDETGGLLFSSLLPTLVAVFLFAALFLPLLMEYG
                     LLEMLGPIFRPVMRPLFTLPGRSTVDNLASFIGDGTVGVLITSRQYGEGYYSRREATV
                     ISTTFSVVSITFAIVVAETVHMQNQFFAFYLSVIVSCLVAAVIMPRIWPLNKIPDEYA
                     KEVPESARTEALPEGKTALRHGFDTATEVGIKAPGVVDFFKSGLKTVVDMWFVILPVV
                     MSIGTIATIIANYTPFFVILGKPFVPFLELMQIPEAAQASQTIIIGFADMFLPSILIE
                     GVQNDITRFVIGALSISQLIYLSEVGGVILGSKIPVSIGKLFMIFLIRTIITLPIISL
                     MAHLLL"
     gene            complement(27565..27825)
                     /locus_tag="RPH49_001331"
     CDS             complement(27565..27825)
                     /locus_tag="RPH49_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124492.1"
                     /translation="MAMTVKKDNNEVRIQWRVADIKIPTSEIKNITQDQDIHAVPKLD
                     SKDVSRIGSTFGKTNRVIIDTEDHEYIIYTQNDQKVYNELTK"
     gene            28002..28517
                     /locus_tag="RPH49_001332"
     CDS             28002..28517
                     /locus_tag="RPH49_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDY5124493.1"
                     /translation="MTGKTHASCGMLVGALTTQYFQTDIFSSVTVIILATLASLLPDI
                     CHTQSKIGRRFKVISFFVRLIFGHRTFTHSILFIAIIAFLLQIIQTPNYYMAAIIIGL
                     VSHVILDMITPKGVKLFYPLPFNVKTPIQFKTGGLVDLSLATALMVGTVYVLFQPFIN
                     DIISNWNTKFL"
     gene            28561..29748
                     /locus_tag="RPH49_001333"
     CDS             28561..29748
                     /locus_tag="RPH49_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDPGP type 1 family protein"
                     /protein_id="HDY5124494.1"
                     /translation="MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAK
                     LYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEGQGLQAIKEGQFAVLLMAGG
                     QGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYF
                     EAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYL
                     EEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNV
                     DCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDEN
                     FGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNTEGKDSVATATEDLRRM
                     GLI"
     gene            29767..30450
                     /locus_tag="RPH49_001334"
     CDS             29767..30450
                     /locus_tag="RPH49_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDY5124495.1"
                     /translation="MSKSSEKSNDTIAETFKDIIPLSFGEEIGNAASHGLAALLTLLV
                     LPYAAVHSYIANGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMI
                     YVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMG
                     WVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLL
                     HLIAILYFM"
     gene            30730..32073
                     /locus_tag="RPH49_001335"
     CDS             30730..32073
                     /locus_tag="RPH49_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124496.1"
                     /translation="MRLKSIVTVIALILIMFMAAIESSIISLALPTIKQDLNAGNLIS
                     LIFTAYFIALVIANPIVGELLTRFKIIYIAIAGLTLFTVGSLMSGLSTHFSMLIISRV
                     IQGFGSGVMMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWH
                     WLFFINIPIAIIAIILVVWTFHFSEEETVAKSKFDTKGITLFYIFIGLIMFALLNQQH
                     LYLNIIGFVLAILIALRLFNVEKKVSSPFLPVAEFNRMITLVFITDLLTAVCLMGFNL
                     YIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHHIEAKLSRKVIYLSSFTLLLLS
                     SIIIAFGIKLPILIACVLILSGISFGYIYTKDSVIVQEETSPIQMKKMMSFYGLTKNL
                     GASIGSTIMGYLYALKSGLFGANLHNILGVVSLISVGLIVVWLIFYREAASQTNE"
     gene            32195..32668
                     /gene="sepA"
                     /locus_tag="RPH49_001336"
     CDS             32195..32668
                     /gene="sepA"
                     /locus_tag="RPH49_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter SepA"
                     /protein_id="HDY5124497.1"
                     /translation="MVMNYLKHKFYNLLTTIIVLFIFVLSGAIFLTFLGFGLYGLSRI
                     LIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATF
                     HLISYMVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK"
     gene            32857..34299
                     /gene="lmrS"
                     /locus_tag="RPH49_001337"
     CDS             32857..34299
                     /gene="lmrS"
                     /locus_tag="RPH49_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter LmrS"
                     /protein_id="HDY5124498.1"
                     /translation="MANVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELN
                     INESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFG
                     VLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLI
                     IDQASWRVPFIIIVGIALVAFIFGLISISSYNEVKYTKLDKRSVMYSTIGFGLMLYAF
                     SSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNISNALLNLRVFKNRTFALCTISSMI
                     IMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLI
                     YTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEIS
                     HGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFSSTSPSHLTATEIKQQSIAIGVDISF
                     AFVAVLVMAAYVIALFIREPKEIESNRRKF"
     gene            34447..35511
                     /locus_tag="RPH49_001338"
     CDS             34447..35511
                     /locus_tag="RPH49_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-loop NTPase"
                     /protein_id="HDY5124499.1"
                     /translation="MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVK
                     LAMAQLGGAPQLDLQMAVVNVLKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEG
                     LLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGI
                     DEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIE
                     YLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVI
                     ENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSD
                     DRLGKIYSSIAQKVIAATNK"
     gene            35600..35785
                     /locus_tag="RPH49_001339"
     CDS             35600..35785
                     /locus_tag="RPH49_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124500.1"
                     /translation="MLSNKRVEKEAGCEHKKFLKKLLTLNSKVDNMIKSSKTTQLFLK
                     KNFKSVKLTIEITIKTI"
BASE COUNT        12247 a         5028 c         6682 g        11902 t
ORIGIN      
        1 tgttataaga aaatttacat cgttaacaat agatgaattg tattacttta aagaatataa
       61 aaaggagaag gatgataata ttttgtgcga ggagttttca tataagtgtt ccataaaaga
      121 tataaaatat aaaaaattat taaaagctat atccaatcaa gactttaaag ggttagttcc
      181 aaatatcaat cagaatgata attattctga aatatacata attaacaata ctaaaaacgt
      241 aatatatcat ttatatgatg atagaggtct atggctagct tttaataata atgaagatta
      301 tgcaagatat tctgaaaaat ataatgattt aatatcagaa tttgataacg aagatatcta
      361 attttttaat attcgcagct attatttttt tacttgtttt atgtttattt tttaatctaa
      421 caaatgacaa accattaaaa gtaacatccc aacatcaaac aaaaaacaat tcatcaaatg
      481 aaaatcgtta taaaaccaag tcattaaaca cgcaataatt aaaattttcc actcatttta
      541 atttggaact tcaaacgtcg aattccaaaa acgaaactcc aaattccaaa aacgcaactc
      601 caaaattaaa agcatctccc tgttactcgg gaaatgcttt ttacctactg attaccctgt
      661 tattaatgat tttacaacgg aaaccatgtc gtcatgtatg accaaagtag cgtcgctatc
      721 ataaggtgtt cgatctttat tgataataat taaattgtcg cctttaaaat ttgatattaa
      781 tcctgcggca ggttgtacaa cgagtgatga acctagtaca acaagggtgt cggcatgttc
      841 aattttattt aatgcccgta tgatggtagg ttgatctaac atttcaccgt ataatacgat
      901 gtccggtcga atggcgccac cacaattatc acaatgtttc aaagttctat caatgacatc
      961 tgacttcgta taagatttat gacatgcatt acaataaaaa cgatttaacg tgccatgtaa
     1021 ttcatcaaca tgttgacttc cagcgtctga gtgcaaacca tcgatatttt gcgtgatgac
     1081 acctaaagat tgttgattac gttctaattt tgcaatccaa tcatgaacga tattaggctt
     1141 cgtatcgaca aatagtaaac gcttatggca gaaattgata aaaccttcag gatcatcttc
     1201 taaataatca cggcttaaca agtattctgg tgaaagccca tcttttgaaa tttcatcaaa
     1261 taagccaccc attgaacgga aatctggaac accacttgcg acagatacac cagcacctgt
     1321 gaaaaatgta atacgattcg aactatctat aatatgtttt aatgtctcta aatcattttc
     1381 caaattaaac accccatcaa aataatgaat gatttataac gtcttttgct tttattatag
     1441 tatattcatt ttacgattat caaaagcgca gtttaaacag ttctttttaa aaatgaatta
     1501 tacatataat cgaacagtta aattatatta gtttttacgc aatttttatt atagaataag
     1561 catgtatatt aaaattgatg tctaaacata aaggataatg acccatcgcc taaataaagg
     1621 aggcaatttt acattgaata aacatgaacg tttggacgaa attgctaaac tagtgaataa
     1681 aaagggcacg ataagaacga atgaaatcgt cgaaggttta aatgtgtctg atatgacagt
     1741 tcgaagagat ttaattgaat tggaaaataa agggatttta acgaagattc atggtggtgc
     1801 acgcagtaat tcaacatttc agtataaaga aatatcacat aaagaaaaac atacccgtca
     1861 aattgcagaa aaacgattta tagctagaaa agctgcatca ttaattgaag atggggatac
     1921 tttgtttttc ggaccaggaa caacagtgga actattagca gaagaagtca atcatcatac
     1981 gctcacaatt attacgaatt gtttgccggt gtataaaatt ttgttagaaa aacaaacagc
     2041 acattttcgt gtctatttaa ttggtggtga aatgcgccat attacagaag catttgtagg
     2101 tgaaatggcg aatgccatgt tggaaaaact aagatttagc aagatgttct ttagtagtaa
     2161 cgcagtaaat aaaggtgctg tgatgacatc tacattagat gaagcctata cgcaacaact
     2221 ggcactcagt aattcaattg aaaaatactt gttaatcgat catacgaaag ttggcaaaga
     2281 agattttaca tcattttgtc agttaaacga attgactgca gtggtcatgg attatgaaga
     2341 tgaagaaaag gtagaaacga ttaaaacata tattgaagta gtcgactaaa ttaaaaatat
     2401 aactgcattg ttaaaatatg tgtctatatg ctcgtaagtg aatgtgaatt tgcattcatt
     2461 tatgggctat tttttatgca aatttatgta aacgggaacc tcgacaaagt tttactacaa
     2521 tttcagacga atacctaatt aaaacaacac cacagtatga atgttcactt attgtttgaa
     2581 aatatgtcat aaacaaacag attataaaca tattatgttg atttattgtt tgtttatgtt
     2641 tataatttaa acgtaatcaa attgaaagcc ttttctcaag attttcataa cctacaaata
     2701 aacatgtcat attttaagaa aggtatttca aaattaaagt aaaaaggagt cttattatgg
     2761 cgattattat tggttcagat gaagctggca aacgattaaa agaagtcatc aaatcatact
     2821 tattagacaa taaatatgat gttgttgacg taacagaagg acaggaagtt gactttgttg
     2881 atgcaacttt ggctgtagca aaagatgttc aaagtcaaga aggtaactta ggtattgtta
     2941 tcgatgcatt tggtgcaggt agctttatgg ttgctacaaa aatcaaaggc atgattgctg
     3001 ctgaagtatc agatgaacgc tctggatata tgactagagg ccataacaat tcaagaatga
     3061 tcactatggg gtctgaaatt gttggagaca cattagcgaa aaatgtcgtt aaaggttttg
     3121 ttgaaggtaa atacgatggt ggtagacacc aaatccgtgt agatatgctt aataaaatgt
     3181 gctagggagg aaaaattact atgaagattg cattaggatg cgaccatatt gttacagata
     3241 caaaaatgcg tgtatctgaa tttttaaaat caaaaggaca tgaagtcatt gacgtaggaa
     3301 catacgattt cacaagaaca cattatccaa tttttggtaa aaaagttggc gaacaagttg
     3361 ttagcggtaa tgcagactta ggtgtttgta tttgtggaac aggtgttggt attaacaatg
     3421 ctgtaaataa agtacctggc gttcgttcag cactagtacg tgatatgaca tcagctttat
     3481 atgctaaaga agaattaaat gcgaacgtta ttggctttgg tggacgtatt ataggtgagt
     3541 tattaatgtg cgatattatc gatgcattta ttaatgctga atataaacca actgaagaga
     3601 acaaaaaatt aatcgctaaa attaaacatt tagaaacaag caatgcagat caagctgatc
     3661 cacatttctt tgatgaattc ttagaaaaat gggacagagg cgaataccac gattaaggga
     3721 cgacacatat gattttaact ttaacattaa atccatccgt tgatatttca tatccattaa
     3781 cagcattgaa attagatgat gttaatcgtg ttcaagaagt aagtaaaaca gctggtggta
     3841 aaggtttaaa tgtaacaaga gtacttgcgc aagtaggtga gccagtcctt gcgagtggtt
     3901 ttattggcgg tgaattaggt caatttattg ctaaaaaatt agatcatgcc ggtatcaagc
     3961 atgcatttta taacattaag ggtgaaacac gaaactgcat tgcaatttta catgaagggc
     4021 aacaaacaga aattttagag caaggaccgg agattgataa tcaagaggct gcaggattta
     4081 ttaaacattt tgaacaatta ttagaaaaag ttgaagcagt tgctatttca ggtagcttac
     4141 ctaaaggatt aaatcaagat tattatgcac aaatcattga acgatgccaa aacaaaggtg
     4201 tgcctgtaat attagactgc tcgggtgcaa ctttgcaaac agttttggaa aatccataca
     4261 aaccaacagt cattaaacca aacatttctg aactatatca attgcttaac cagccacttg
     4321 atgaaagttt agaaagtttg aaacaggcag tgtcacaacc cttattcgaa gggattgagt
     4381 ggattattgt gtctttaggt gaacaaggtg cattcgctaa gcacaatcat acattctata
     4441 gagtgaatat tccgataata agtgtattaa atccggttgg ttcaggtgat tctacggttg
     4501 ctggaattac ttcagcaatt ctcaatcatg aaaacgacca cgatttacta aaaaaagcca
     4561 atactttagg catgctgaat gcgcaagaag cacaaacagg ttatgtcaat ttaaataatt
     4621 atgatgattt attcaatcaa attgaagttt tagaggtgta aaaaatgtca aaatcgaatc
     4681 aaaaaatcgc atcaattgaa caattaagta acaacgaagg tatcatttct gcattagcat
     4741 ttgaccaacg tggtgcttta aaacgcatga tggcaaaaca tcaaactgaa gaaccaactg
     4801 tagctcaaat tgaacaatta aaagtattag ttgcggaaga attaacacaa tatgcatctt
     4861 caattttatt agatcctgaa tacggtttac cagcttctga tgcacgtaac aaagattgtg
     4921 gattattact tgcttatgaa aaaactggtt atgacgtaaa tgctaaaggt cgtttacctg
     4981 actgtttagt tgaatggtct gcaaaacgat taaaagaaca aggcgcaaat gctgttaaat
     5041 tcttacttta ctatgatgta gatgatacag aagaaatcaa tattcaaaag aaagcatata
     5101 tcgaaagaat cggttcagaa tgtgtagctg aagatattcc attcttttta gaagtattaa
     5161 catacgatga caacattcct gataacggta gtgttgaatt cgcaaaagtt aagcctagaa
     5221 aggttaacga agcaatgaaa ttattctcag aaccacgctt taacgttgat gtattgaaag
     5281 ttgaagtacc agtaaacatg aaatatgtag aaggctttgc tgaaggtgaa gtggtttata
     5341 caaaagagga agcggcacaa cactttaaag atcaagatgc agcaactcat ttaccataca
     5401 tttacttaag tgctggtgtt tctgcggaat tattccaaga aactttaaaa tttgctcacg
     5461 aagctggtgc taaattcaac ggtgtacttt gtggccgtgc tacatggtct ggtgctgttc
     5521 aagtatacat tgaacaaggt gaagatgctg ctcgtgaatg gttacgtaca actggtttca
     5581 aaaatattga tgacttaaac aaagtattaa aagatactgc gacatcttgg aaacaaagaa
     5641 aataagtata aaaggggatt aatgctatga atagagaaga agtccaatta ttaggttttg
     5701 aaattgttgc atttgcaggg gatgcacgtt ctaagttttt agaagcatta acagcagctc
     5761 aagctggaga ttttgcaaaa gcagatgcac tgatagaaga aggaaacaat tgcattgcgg
     5821 aagcgcatag agcacaaaca agcctgttgg ctaaagaagc gcaaggtgat gatattgcat
     5881 atagtgtgac gatgatgcat ggtcaagacc atttaatgac aacaatttta ctgaaagatt
     5941 taatgaagca tttattagaa ttttataaaa gagggtgatg acaatgatgc aaaaattgat
     6001 cgcacaaatt gaaaaaggga agccattttt cgagaaatta tcacgtaaca tatatttaag
     6061 agccatccgt gatggattta tttctgcaat gcctgtcatc ttattctcaa gtatctttct
     6121 attaattgca tacgtgccaa atatatttgg ttttaaatgg gataaaggca tggaagccat
     6181 tttaatgaaa ccatataact atacgatggg acttgtagca tttttagtag caggaacgac
     6241 agcgaaatct ttaacagatt catttaatcg taagctagaa agtacaaatc aaattaactt
     6301 tatttctacg atgctagcag cgatgtgtgg attcttgttc ttagcttctg atccagccaa
     6361 agatggtgga ttcttaagtg catttatggg aactaaaggt ttattaacag cattcttatc
     6421 agcatttgta actgttattg tttataactt ctgtgtgaag cgcaatatta caattaaaat
     6481 gccgaaagaa gtaccgccga atatttcaca agtatttaag gacttaattc cattttcagc
     6541 ggtaatcatc attctttatg cattagattt agtcattcgc aacagcttta aatcaaatgt
     6601 agcggaaggt attttaaaat tattcgaacc attatttaca gcagcagatg gatggattgg
     6661 tgtcacaatt atctttggtg cctttgcatt attctggttt gtaggaattc atggtccatc
     6721 aatagtagaa ccagcaattg cagccattac atatgcgaat atcgaagcga acttcaagtt
     6781 gcttcaagct ggagaacacg cagataaaat tattacatca ggtacacaaa tgtttatcgt
     6841 tacttttggg ggtacgggtg cgacattggt cgtcccattc atgtttatgt ggatgacgaa
     6901 atctaaacga aacaaagcga ttggacgtgc atcagttgta ccaacattct ttggtgtaaa
     6961 cgaaccaatt ttatttggtg caccactagt attgaatcct gtgttcttta ttccatttgt
     7021 attagcacca attgttaacg tatggatttt caaacttttc gttgaagtgt taggaatgaa
     7081 tagttttagt gtgaatttac cttggacaac accaggtcca ttgggcatta tcatgggtac
     7141 aggttttggt ttatggtcat tcgtactagc tattactttg attgttgtag atatcattat
     7201 ttactaccca ttcctaaaag tttatgatag tgaaattctt gatgaagaag aaggacgtaa
     7261 agaaagtaat tcagatttaa aagaaaaagt tgcagcaaac tttgatacga aaaaagctga
     7321 ttcaatttta gcggcaagtg gtgtatcaga cgatgcagct aaagcttcaa atatcacaga
     7381 acaaacaaat gtcttagtac tttgtgccgg tggtggtaca agtggattat tagccaacgc
     7441 acttaataaa gcagctgaag aatatcatgt gccagtgaaa gcagcagctg gcggatatgg
     7501 cgcacatatg gacattatga aagagtacca attaatcatt ttagcgccac aagttgcgtc
     7561 taactatgaa gatattaagc aagatacaga tagattaggt attaaattag cgaagactca
     7621 aggtgctgaa tatatcaaat tgacacgaga tggccaagca gcccttgatt tcgttcaaca
     7681 acaatttgaa aattaagaat aggagttttt catatgacta aaacattacc tgaagatttt
     7741 atttttggtg gagcaacagc agcatatcaa gcagaaggtg cgacaaatac ggatggtaaa
     7801 ggtcgtgtag catgggatac gtatttagaa gaaaactatt ggtacactgc agaaccagcg
     7861 agtgattttt ataacagata tccagtggat ttagaattaa gtgaaaaatt cggtgttaat
     7921 ggtatccgta tttcaattgc atggtctcgt atcttcccaa atggatatgg cgaagttaac
     7981 cctaaaggtg ttgagtatta ccataagtta tttgcagagt gtcataaacg tcatgtcgaa
     8041 ccatttgtaa cattgcatca ttttgataca ccagaagtgt tacacaaaga tggcgatttt
     8101 ctaaatcgta aaacgattga ctactttgta gattatgctg aattttgttt taaagaattc
     8161 ccagaagtaa aatattggac tacattcaat gaaattggac ctattggtga tggtcaatat
     8221 ttagtaggta aattccctcc aggtattaaa tatgattttg aaaaagtttt ccaatctcat
     8281 cacaatatga tggttgctca tgcaagagca gtaaaattat ttaaagatgg cggctatcaa
     8341 ggagaaattg gtgttgtaca cgcattgcca acaaaatatc cgttcgatcc atcaaatcct
     8401 gaagatgttc gtgcagcaga attagaagat atcatccata ataaattcat cttagatgca
     8461 acatatttag gtaagtattc tcgtgaaacg atggaaggtg tgcaacatat cttatctgtt
     8521 aatggcggta aattaaacat tacagatgaa gattatgcca ttttagatgc agccaaagat
     8581 ttaaacgact tcttaggtat caattactac atgagtgatt ggatgagagg ttacgatgga
     8641 gaatctgaaa tcacgcataa tgcgacaggt gataaaggcg gttctaaata ccaacttaaa
     8701 ggtgtcggac aacgtgaatt tgatgtcgac gtacctcgca cagactggga ctggatgatc
     8761 tatcctcaag gtttatatga tcaaatcatg cgtgttgtta aagattatcc taactatcat
     8821 aagatttata tcactgaaaa tggtttagga tataaagatg aatttattga atctgaaaaa
     8881 acagttcatg atgatgcacg tattgattat gtaagacaac atttaaacgt tattgcagat
     8941 gctattaaag atggtgcaaa tgttaaaggt tactttattt ggtcattaat ggatgtgttc
     9001 tcttggtcaa atggttatga aaaacgatat ggtttattct atgtcgattt tgagactcaa
     9061 gaacgttatc ctaagaaaag tgcttattgg tacaaagagt tagccgaaac aaaagaaatt
     9121 aaataattat agatattaaa aggcctatca gtcgagtgct ggtaggtctt tatttataga
     9181 aagagataaa ttaaacatgc atatacatat ttatatatta atcaatgggt gacacaccat
     9241 tgaaagctaa agaagcaatc aattaacaaa cgttaacgga caactttcca aagtcatctt
     9301 aaaagttaat gatgtattca aaatcaacta aaggacattt ttaatcacat cctttatact
     9361 tatataaaag acatgaatgg gagttaaaag tgtgaagaaa atttttgtaa ttattacgac
     9421 attgttagcg gtcgctatta ttataggctc tattattacg gtggtgttta gtcaacgaca
     9481 ggcacaaaca tttaaaatac aacaacagca atttgttaaa aagccaattc caacattgtt
     9541 cttacatgga tttggtggta gtgccaattc tgaaaagttt atggtgaagc aagcagaaaa
     9601 aagaggggta actaaagata tcatcactgc ttacgtttca aaggatggtg cagtgacatt
     9661 taaagggaaa ctaagaaaag atgcagtgaa tcctattgtg aaaattgaac ttgaaaataa
     9721 cagacaaggc tatttggata agaatgctgc gtggtttaaa aatgtactga ctaagttaca
     9781 atctgaatac aatttcgata aattcaactt tgtcggtcac tcaatgggga acttaacatt
     9841 tgcacaatat atgatgacat atggtaacga caagtcactg ccacagttaa acaaacaagt
     9901 gaatattgca gggacattta atggtgtttt aaatatgaat gaagatgtca atgaaattac
     9961 agttgataaa gatggtaaac caagtcgaat gaatcaacct tatcagcaat tacgcgtgct
    10021 aaaagatatt tataaaggta aaggtatcga agtgctaaat atttatggag atttgaaaga
    10081 tggtacacat tcagacggca gagtgtctaa tagttcttcg aaatcattaa aatatttact
    10141 gggaaatagt ccgaaaagtt atcgagaatc taaatatgaa ggtgagcctg cacaacatag
    10201 tcagcttcat gagaatgaaa atgttgctaa tgagttaatc gacttcttat ggaaaaaata
    10261 aagcaactgc tagtttttct ggggcaaaaa agcttgtaat attagagctt ttcaaaaatt
    10321 atctattgtt tgagagtttc cataaaatgt ctaagtcgta acattttaaa tttatgatta
    10381 tagcaaatat aatgtggttg aagttacatg aatgaatcag tgcttaagtc aaaatataac
    10441 aactaagaat gtatttgcat acagacatca cgaagacaca attcaaactt aacgcttaag
    10501 taacaaataa gtaaaagttt caaataaaga aaggtgatta atgatgcaaa ataaacaaat
    10561 tctttttaac aaaataccag aaggcatgcc tcaagaggat acattcaaaa ttgaagagat
    10621 tgacacgcct aaacttgaga gcgatggtgt acttgtacaa acgctgtata tttcagtgga
    10681 tccatatatg agaggacgta tgactaaggc agattcgtat gtacagcctt ttgaaattgg
    10741 taaaccgatt gttagccatg tcgttgcaaa agtaattgat tcgacactcg cagattataa
    10801 aaaaggagat gtcgttgtag gtatgttgcc ttggcgaatc attaatcatg tccaagcgga
    10861 tcaaattact aaagttccaa cgacagatgt accacttgat ttatatttaa gtgttttagg
    10921 aatgccagga caaacagcat atcatggtct gcttgatatt ggacaaccta aagccggtga
    10981 tactgttgtg gtttcagctg catctggtgc tgtaggttca gttgtaggtc aaattgctaa
    11041 gattaaaggt tgccgtgttg taggtattgc gggtggcgac aaaaaagtaa attatttaac
    11101 agagacactg ggctttgacg ctggtattga ttataagaaa gaggattttg cagaagcgtt
    11161 agcacaagca gtaccagatg gtattgatgt ttattttgaa aatgttggtg gtacagttgg
    11221 cgatgaagta tttaagcatt taaatcgttt tgcacgtgta ccagtatgtg gcgcaatttc
    11281 gtcatataat catcctgaag ccgatatcgg accacgtatt caaggtacgc ttattaagaa
    11341 gcaagtaatg atgagaggct tcttagtaag tgaattcgcc aatgctttta aagaagctag
    11401 tgaacagctc gcaacatggg ttcaagaagg taaaattcag tcacaagtaa ccattgaaga
    11461 tggttttgaa aatgcgccac atgcatttaa aaatttattt actggcgata actttggtaa
    11521 acaagttatt aaagtaacgg aataataaag tatacgtttt aacaaactaa ctttgttaat
    11581 tgaccaaaat ttaataattt tttatctaaa gcaaatttgt tcagtaacat ggtagaaata
    11641 agtctaaaat gtaatacgaa aggcgtctgt aattatttat atattcagat gaaaaaggag
    11701 tcatgatgct gcgataaaag cacacatggc ttctattttg tataataaga aataagttca
    11761 taaatgaggt gaaacgatat gaaaatgata ggatttgaaa agccctttaa attggaagaa
    11821 ggaaatttat ttaaagtata cgaacaaaga aagccaacgc cagaaaacga tgatatctta
    11881 gtcaaagtaa atagcattag tgtaaatccc gtagatacaa agcaacgaca aatggaagtc
    11941 actcaagcac ctcgtgtact tgggtttgat gctattggta ctgttgaagc tatcggacca
    12001 gacgttacat tatttagtcc gggtgacgtt gtattttatg ctggatcgcc aaatagacaa
    12061 ggatcaaatg cgacatatca attggtttca gaagctatag ttgcaaaagc gccacacaac
    12121 ataagcgcta atgaagcggt tagtctaccg ctaactggta ttacggcata tgaaacgttt
    12181 tttgatacat ttaaaatttc acataatcct tctgaaaatg taggtaaatc cgtgttaatc
    12241 attaatggcg ctgggggtgt aggaagtatt gccactcaaa ttgctaaacg gtatggttta
    12301 actgtcatta caacagcatc acgacaagaa acaacagagt ggtgtgaaaa gatgggagca
    12361 gatatcgtat tgaatcataa agaggattta gtgcgtcaat ttaaagaaaa agaaattcca
    12421 ttagtagatt atatattttg tacctataat acagacttgt attacaatac tatgattgaa
    12481 ctgataaaac cattagggca tattacaact atcgtagctt ttaatgaaga tcaagattta
    12541 aatgcattaa aattaaaaag tataacattt acacatgaat ttatgtttgc gcgtccaatt
    12601 catcgaacgc ctgatatgat taaacaacat gagtatttag aagatattac gaaaaatata
    12661 gaatcaggac attaccaacc aacaacgaca caagtttttg aaggtttatc acctgaaaac
    12721 ttatatcaag cacatctatt gttggaaaaa cagtcaatga ttgggaaatt agtaattaat
    12781 atatagttta gtaagtaaag tcgccttatg cagaaaatac tgtatggggc gacttatttt
    12841 tgtgtctagc gactattgat tctaaaggga aatatgacaa cttagaaggt atcaattcaa
    12901 taatgcatta gaaaggcatt acttaaatac aataaaatac tttgttgttc aatgataaat
    12961 aatttgagta tgttttatat atcattttta aaagatgaag cattattaat tgtgtctata
    13021 taaaattaca aatgattaaa atgttgcagt tgtgggtatg aatttaccat tacacagaaa
    13081 gggtttgtat ttatgaaaaa taaatcagta agtctagtgt tttgggtatc gttagtgatt
    13141 tgtacgatat ttgttgcttt tggtgcaata tttccgaaac agttagaaaa actcacgcaa
    13201 aacattacta catttattgc gctacatttt tcttggtatt atttattgct cgttttagtt
    13261 attttatttg tctgtgtgta tattttattt tcaagatacg caaacattac attaggtgaa
    13321 gaaggcgaag atcctgaatt ctcattgccg tcttggtttg ctatgttatt tagtgctggt
    13381 atgggaatag gacttgtgtt ctggacaaca gcagaaccaa tcagtcatgc cttcaaatta
    13441 acgcctattc ataaagctgg cacgcaatct gcaattaatg atgcaatgca gttttcattt
    13501 ttccattggg ggattcatgc atgggcagtc tatggtattg tcgcgcttgt gtttgcatat
    13561 tttagctttc ataaaggata tcctggctta gtcagcgcta cattgacgcc tttattaggt
    13621 gaaaaggcaa tgcgtggacc tttaggtggt gccattgatg tattggcagt catagctaca
    13681 gtaacaggcg ttgctgcaac attaggtttc ggtgcattgc aaataaacga aggtttacat
    13741 tttttattta atgtaccgag taacttcacg atgcaagtaa tcttgattgt cattacaacc
    13801 atattattta cttggtcagc atggtcaggt atcgataaag gtatcaaaac gttgagtaat
    13861 atcaacatgt tacttgcttt tgtagtactt attggtcttt ttattgttgg gccaacgcta
    13921 tacattttaa atacatttac gaatggtcta ggtaattata ttgcaaattt ctttagtatg
    13981 agtttacgca ttccgtcagg cggtcaaaaa ttccaatggt tacaaaattg gacaatcttt
    14041 tactgggcat ggtggatatc ttgggcacca tttgtaggta tatttattgc acgtgtgtca
    14101 aaaggacgta cgattaaaga atttattcta ggtgtacttt ttgtcccggc attagtttgc
    14161 tttatattct ttgcggtatt cggcgcgtca gcaatttact tacaagataa tcatattgcc
    14221 gatattgcta aagctgcgac agaaacagca acctttgcaa cgctacaaca ttacccacta
    14281 ggttttgtat taagcttaat tactttactt gttattatga ttttctttgt tacatcagcg
    14341 gattcggcaa cttatgtttt aggtatgttg agttcaagag gtgatattaa tccgaagtca
    14401 tttgtcaaag tgagttgggg tatcattatg gcattatttg caattatcat gatctacaca
    14461 ggtggtactc aagcgattca aaatttatta atcattgctg cgttaccatt ttccgtggtc
    14521 attatagcga tgatatggtc gcttttaaaa tctttgagtg aggagaaacc gagaaatagt
    14581 aataaggttt taattaaaca tcgtgaccca gatattttag aatatcgttc ttcaaaacat
    14641 attgacgaaa attaattaat aatgaggttt tatttacaaa aactagggaa tatattacta
    14701 aatggtactt catcttatat attaaaaata aatttatagt tattaattta ttatgtttaa
    14761 gaaaaaatct gatgggtaca tatttaatat gtttttaaat taactttaac taaggaggtg
    14821 tcgttagggg tgaaacgact taaaaacttt atccttggct tattaatagt agtaatcgtg
    14881 gggttcctgt tattcatgta tatccaagat ggacgtataa ctgaatatca agactacttc
    14941 cttcaatttg aatggttcca accattactt atttcacttg ctgcactatt gatattaata
    15001 ggtcttatat tagtatttag tatcttcaaa cctacgcatc gaaaacctgg attatacaaa
    15061 gacttcgatg atggtcatgt ttacgtatct cgtaaagctg ttgaaaagac ggcattcgat
    15121 acggttgcaa aatatgatca agtaagacaa ccaaatgtag ttgcaaaact atataacaaa
    15181 aaaaataaat cttatatcga cattaaaact gactttttcg taccaaataa tgttcaagtt
    15241 caatctttaa ctgaagcaat tcgttcagat attaaaaaga atgtagaata tttcacagaa
    15301 atgccagtac gtaagttaga agttaatgtg agagatcaga aaacttctgg tccacgagtg
    15361 ttgtaaggga ggtatatcat ggctaacaat cataaccaaa acggacaaga ctctacacaa
    15421 caagtgatta attttttaaa agtatttaaa tggagaatcg ttggtttctt agcgtttcta
    15481 ttaatcgcga tattattctt aacgttaggt ttttggaaaa caatacttat catcgtttta
    15541 tgtttaattg gtgtaggtat tgggtatatg aaagaccgta agcaagattt tatgaatttt
    15601 ttaaatcgat ggagttaatt catcaattta gaatttaatt aaaaaaatat aaaaaacaat
    15661 aagttaaagg agaatctatt atgactgtag ataacaataa agcaaaacaa gcatacgaca
    15721 atcaaactgg tgttaacgaa aaagaaagag aagagcgtca aaaacaacaa gaacaaaatc
    15781 aagaacctca attcaaaaat aaattaactt tctctgatga agttgttgaa aaaattgctg
    15841 gtatcgctgc acgtgaagtt aaaggtatct tagacatgaa aggtggctta actgatacat
    15901 tcactaatgc attctcaagt ggcaacaacg ttacacaagg tgtatctgtt gaagttggtg
    15961 aaaaacaagc tgctgtagac ttaaaagtaa ttttagaata tggtgaatca gcacctaaaa
    16021 ttttccgtaa agtaactgaa ttagtaaaag aacaagttaa atatattact ggtttagatg
    16081 ttgttgaagt taacatgcaa gttgacgatg taatgactca aaaagaatgg aaacaaaaac
    16141 acgaaaaaaa taatgaaaac aataaccaag aaagacaagg tttacaataa gttattcgat
    16201 aaaaaagctc ggcacaccat tttagtgccg agcttttttg tgatttttaa taatttgaat
    16261 atgagaaatg tatctttctc tcatttgttt agattgtatt taataagtta atgtaatcct
    16321 tgagctcacg attaataaaa ttctataacc ttaattattt tctcgataca aagggttatt
    16381 aactttaata taagtataat gatgtgcctc atcttcaaga cgcattgttg taacacactt
    16441 ataatctata aatggcgcga acatggtatc tttaatttca tttatgcgat tctcatttac
    16501 ttgattagat ttgtgtgtcg aaagcacaag ttgatcaaag atgttatcta gtacatcacg
    16561 aacgatatac cacatatgtc tttccaagtt tgaatcattt gatgctttag agattgtaag
    16621 aattaattcg cctaaatggt tttgaacggt agaataaaag gctttgttaa acacagacgt
    16681 ttttgaatca gtaagaattc ttgatttttc atggaaatga gatgtactgt atcccatttc
    16741 atttagttgt gctttatcaa ttcttaaacc ttcaaagtct ctaatataca tcgtgtccaa
    16801 taaaccatct ttccgaaatg ttgcaatagc attttgcaag tgagcctcta atgcaatgcc
    16861 atatttagta actagtggga ttacgagacc aagcaatgct ttactataag tttcaatcca
    16921 cgatttcgcc gatgattcaa aatcagacaa tgatgcagct gattgataac gtttaatcaa
    16981 tgtcacgaca ggtgattcat tgttaaatgg gtaggttgca actaaacttg aaggaatcat
    17041 tggtgtgact tcttgtggaa tcatttggta tatgtttttt ctaaataatg tacctaattg
    17101 ttcacttcgt tcagtttgat agtctgcttc gtcttgctca ttataaaaat gaataccagc
    17161 aacttcatca ataattgttg atgcatagga cttaaatatg acatctttct ccaaaatatc
    17221 atttaaaata cgtgtcatta gtggaccatt gtgcgttgtt tgttctgata atgtacgaat
    17281 ttcacctgta atatgaacgt ttgtcgacaa tttgatgtgt ggcgacatag ctgggtattt
    17341 aggaactaat gttctgaaag ataaaccagc ataataatcc aacgtatgtt ttgcttcaat
    17401 gattaattct ttatctactt ctgcttgata atcagaatgt aatacgtcat ctaattgcca
    17461 tggatgtaca atcataatgt gataatcatt aaagttaaac tttggcgtaa attcattttc
    17521 taattgttta attaagtccg gaaatagttg atgaacagtt gtatcataat ctttagacag
    17581 tgacatagta cggcttaatt tactgtgaat cagtactatt ttcaacttaa taggttgatt
    17641 gaattctgaa gaatatagga atgtttgtaa tgcatttaaa cctttacgta atttagcccc
    17701 aggatgtagc ggatgacctt caataacggc ttgctctgaa cgcaagtaac tatcttcgct
    17761 attttcgata atattaaata aaggtgtaga atcatgttgc attgacagtg cttgatagct
    17821 aattgcaaat gtcatattag ttgcactgtt tattaaatct tgctgaaatt gatcactagc
    17881 agcatttttt aaatctggtg cttcaattaa aatacactca agaatttcat ttggatggtg
    17941 tactcgtgta atcgtatttg taatgtcatc tttaatgtag aaagggcctt caacatcaat
    18001 tcgatcaaag gcatgttctc cagtgatagg agcatataat gtttgcttag cttgtgggaa
    18061 ctggatttct agtatatgag tcgttgagat atctaacata atcaaatcac gactcaatat
    18121 tttcttactt tgagtgcgcg ctttaactaa gttttcgcga tgcattgatg tgactaatct
    18181 ctgagtgact ttatctcttc cttgtaaaat catctcttta aaaatattag cccaatcgtt
    18241 attatgttgt tgtaaaaata aatatgtttc ttgttcttct ttgttaaatt ttaatgtctg
    18301 ttctttaaaa attaagttca agttcataat tcacctctat gaaatatttt acaaaagcaa
    18361 gatagatttg tataatccat attaatgata atgattctta ttatcaacag aatgcgggtg
    18421 taagttttat gacaaaatat ttttttagca gttcttttct actatttcta ggtaattgga
    18481 ttggacaaat agggctaaat tggtttgtac ttaccactta tcataacgca gtttatctgg
    18541 ggattgtcaa tttttgcaga cttgtaccaa tattattact aagtgtgtgg gcaggggcaa
    18601 ttgccgataa atatgataaa gggcgattgc tgagaattac aatttcatca tcatttttag
    18661 taactgcaat tttatgtgtg cttacgtata gtttcactgc aattccaatt agcatcatta
    18721 ttatatatgc gacattaaga gggattttaa gtgcggttga aacaccttta agacaagcaa
    18781 tcttaccaga tttatcagat aaaatatcta ctacacaagc tgtatcattt cattcattca
    18841 tcattaatat ttgtcgttca atagggcctg ccattgctgg tgtcatatta gcagtctatc
    18901 atgcgccaac aacatttctt gcacaggcaa tttgttattt tatcgcagtt ttattatgtt
    18961 taccattaca ttttaaagta actaaaatgc ctgaagatgc aacaagatat atgcctttaa
    19021 aagtcattat agattacttc aaattacata tggaaggtcg acaaatattt ataacatcat
    19081 tattgattat ggcgacaggt ttttcatata cgacactttt accagttttg acaaacaaag
    19141 tatttccagg gaaatctgaa atatttggta tcgctatgac gatgtgtgcc attggtggta
    19201 ttattgcaac gctagtttta cctaaagtac ttaaatatat tggtatggta aatatgtatt
    19261 atttaagttc atttttattt ggcattgctt tgttaggtgt ggtatttcac aatattgtca
    19321 tcatgttcat ttgtattaca ttgattgggt tatttagtca atgggcacgt acgacaaatc
    19381 gcgtttattt tcaaaataat gttaaagatt atgaacgtgg taaagtactg agtattatta
    19441 tgatggatag aggtatgatt ccattgggaa gtctgttaat gagtatatgt gcagatgtgt
    19501 ttggcattgt tagaactttt tcaataatgg gaataagtac tatatgcatt acaatggtat
    19561 tctattttat aaatagaaag ttgaagttaa agttggagga aagtaatcat ggtatatctt
    19621 gaatgggcaa aggcagatag aaatattcaa tatcgtgtaa ttaacgccat tattaaagaa
    19681 cgtatttacc ccgagcaaac atttatttcg caaaaaggat ctttaattga aattcagtat
    19741 catatgcatg tgttgactat tgaagttgtt agaaaaagtg cattagaacg ctatgagttt
    19801 acaggggata ttacttattt aaataaaggt gaaacgtcat taattataac tttagaaggt
    19861 ttgttagatg tgttgaatca tgactttgat atccctattt cagagcgact acgcgaagag
    19921 ttaatacaca gtcgagatag tttagttgaa acatataagc aaatgtctca tagacaaaca
    19981 ttaataagtc aaagttttaa attttcaaga ttaccacaag atattaactt tttttcatgg
    20041 ttacaacatg taaaagatag tgataagaca gatgatttaa cttattctga gagtttggta
    20101 ccagaggggc atccaacaca ccctttaacc aaaacgaaat tgcccttaac tatggaagaa
    20161 gtacgagcat atgcacctga gtttgaaaaa gaaatccctt tgcaaattat gatgattgaa
    20221 aaagaccatg ttgtgtgcac agctatggat ggtaatgatc aatttattat tgatgaaata
    20281 attcccgaat actacaatca gattcgtgtg tttttgaaga gtttaggttt gaaaagtgaa
    20341 gactatagag cgattttagt acatccttgg caatatgatc atacgatagg gaaatatttt
    20401 gaagcatgga ttgctaaaaa aatattaatt ccaacgccgt ttacaatact ttcaaaagca
    20461 actttatcat ttaggacgat gtctttaatt gataaaccat accatgttaa gttgcccgtc
    20521 gatgtacaag caacaagtgc cgttagaaca gtctcaactg tgactactgt agatggacca
    20581 aagttaagtt atgctttaca aaacatgttg aatcaatatc caggatttaa agttgctatg
    20641 gaaccgttcg gtgaatatgc aaatgttgat aaagatatgg cacgtcagct tgcttgtatt
    20701 ataagacaaa aacctgaaat tgatggaaaa ggtgcaacag ttgttagtgc aagtctagtt
    20761 aataaaaatc caatagatca aaaagttatc gtggatagtt acttagagtg gttaaatcaa
    20821 ggaattacta aagaaagtat tacgacattt attgaacgat actctcaagc attaatcccg
    20881 cctttaattg cttttattca aaattatgga attgcattag aagcacacat gcaaaataca
    20941 gtagtgaact tggggccaca ttttgacatt caatttttag tgagagattt aggtggttct
    21001 agaattgatt tagaaacatt acaacatcgt gtatcagata ttaaaattac aaatgatagt
    21061 ttaatagctg attctataga tgcagtgatt gcaaaattcc aacatgctgt tattcaaaat
    21121 caaatggcag aattaatcca tcattttaat cagtatgatt gtgttgaaga aaccgaatta
    21181 tttaacatag tacagcaagt agtagcgcat gccattaacc caacactacc acatgcaaat
    21241 gagttaaaag atattttgtt tggaccaaca attactgtca aagcgttgtt aaatatgaga
    21301 atggaaaata aagtaaagca atatttaaat attgagttag ataatccgat aaaaaaagag
    21361 gtgtagtact acatggcaca cgttaacata aatatatcga agattaaata taacgccaaa
    21421 gtacttcaaa cagtttttca aagtaaaaat atgcaattca caccagtaat taagtgcata
    21481 gctggtgacc gtacaattgt agaaagctta aaagcgttag gtatcaatca tgttgcagaa
    21541 tccagattgg ataacataat tagtattgca gatcaggatt taacatatac gttattgcgt
    21601 acgcctgcca aaaaagagat ttcagatatg atagaaaaag ttgatatgag tatccaaaca
    21661 gaattatcta ccatacatca aataaatgaa gtagcagaag ttttaggaaa aaaacataag
    21721 attttattaa tgatagattg gaaagatggc cgtgaaggtg ttctgactta tgatgtttta
    21781 gattatatta aagagattat tcacttgaaa aatatccatt ttgtaggttt agcattcaat
    21841 tttatgtgct ttaaatctga tgcgccaagt gatgatgata tctttatgat taatcgattc
    21901 gtctcagctg ttgaaagaga aataggatat cgattgaaaa ttatttcagg tggtaattcg
    21961 agcatgttac cacaactttt atataatgat ttgggtaaaa taaatgaatt gcgaataggt
    22021 gaaacgttgt ttagaggtgt tgatacaacg acaaatcaag cgatagctat gttatatcaa
    22081 gatgcgatta cattggaggc tgagatttta gaaattaaac ctcgagttaa tacacaaacg
    22141 catgaatcat tcttacaagc tattgtagat attggctatt tagacactaa agtcgataat
    22201 atttcaccta tggatcagca tatcaatatt ttaggcgctt cgagtgatca tttaatgctt
    22261 gatttaaatg gtcaaggaca ctatcaagtt ggagatcata tatctttttc attaaattat
    22321 gaagcacttt ctcattcgat gtatatgaaa aatttacata aggtatatat tgatgattca
    22381 aagattgata cgctacttca aaattttgat gtgaaatctc ccgctatggt aaaccaatat
    22441 taatatattt atcaataagt ctaagttgac aagttatact acatatcgtt tacacggttg
    22501 tatcataatt gttcaactta gattttttgt atttgttgat ttatcaaata aagtgcaaca
    22561 gttcgtcaca taaaattgca acagataata tcagctgaat tacagggata acggtcatgc
    22621 taaatggtgt caattgcatt aatgcaaaga tgatatagcc atgatacatt atcagtattt
    22681 tgtctaagga aatgtgctaa ttgtagtcat aattattaga ggaaatatat atagtcatac
    22741 attttagtaa tataaaaaga ttgaacgcta cttgacaatg ataattgtta tcaataaaat
    22801 aataaatgaa gttatacata ttaaggagtg gaacgatgag aggtctaaaa acttttagta
    22861 tattgggatt aatagttgcc ttatttttag ttgcagcttg tggtaatacg gataattcaa
    22921 gtaaaaaaga atcatcaact aaagatacta tttcggtaaa agatgaaaat ggtacagtaa
    22981 aagtacctaa agatgcaaaa cgtatcgttg tattagagta ctcatttgca gatgcattag
    23041 cagcattaga cgttaaacca gttggtattg ctgatgatgg taagaaaaaa cgtatcatta
    23101 aaccagttag agaaaaaatt ggggattata cttctgtagg tacacgtaaa cagccaaact
    23161 tagaggaaat tagtaaatta aaaccggatt taattatcgc tgatagcagt agacataaag
    23221 gtattaataa agaattaaac aaaattgcac caacattatc attaaagagt tttgatggtg
    23281 actacaagca aaatatcgat gctttcaaga caattgcgaa agctttagat aaagaaaaag
    23341 aaggcgaaaa acgtcttgct gagcatgata aattaatcaa taagtataaa gatgaaatta
    23401 aatttgatag aaatcaaaaa gtgcttccag cagttgttgc taaagctggt ttattagcac
    23461 atccaaacta ttcatatgtt ggacaatttt taaacgaatt aggatttaaa aatgcattaa
    23521 gtgacgatgt aacaaaaggt ttaagtaaat atttgaaagg accttactta caattagaca
    23581 ctgaacattt agctgattta aatccagagc gtatgatcat tatgactgat cacgctaaaa
    23641 aagattctgc tgaattcaag aaattacaag aagatgcaac atggaaaaaa ttgaatgcag
    23701 ttaaaaataa tcgcgtggat attgttgacc gtgatgtttg ggcaagatct cgtggcttaa
    23761 tttcttctga agaaatggct aaagaacttg ttgaattatc aaaaaaagaa caaaagtaag
    23821 gtggaagtaa atggctataa aagaaataag tagccaatct gccatagatc ataaaagaaa
    23881 aagacgcaca acactcacgt atatagtgag tttgtgcttt ctttttattt gtatatattt
    23941 aaatatggcg attggttctt cgaaaattaa ttttagcgat atcgttcact atgttactgg
    24001 tcatacagat acgaaagcaa cgtttttatt gcacaatgta cgtatgccaa ggatgattgc
    24061 agggttattt attggcggtg cattagcggt atctggtttg ttaatgcaag caatgacacg
    24121 caatccgcta gcatcaccta aaatttttgg tgttagttct ggcgcgtcat ttgtcattgt
    24181 attagtaacg attattattc catcattaga atattatgca ttatatttgg gtgtgatagg
    24241 tgcatttata ggtggtttaa ctgtttatac actttcaggt gctacgaaag gtatgacacc
    24301 cattaaatta gcattggctg gtatggcgat ccatttgttt tttagtagta tgactgaagg
    24361 tattattatt ttaaatgaga attctaatga acaagtgatg ttttggcttg ttggttcatt
    24421 atccagtatg aagtgggatg agattttaac cattctacca tggcttattg gtgcattaat
    24481 tgcaacagtc tttattgggc gtcagttaac gataatggaa cttggcgatg acattgctaa
    24541 gggattgggt caaaatataa ataaagttag aattatcatt ggactattag tcattattct
    24601 tacaggtatg tcggtgtcag tggcaggacc aattggattt gttggcttaa tcgtaccgca
    24661 tatagtcaaa cgctatgtga gtaagaatta tttagtcatg attccattaa catttattat
    24721 aggtgcagat ttgttactac tatcagatgt attaagtcgt ttaattacat atccttatga
    24781 atcaccagta gggattgtta catcattcgt aggtgcactt tacttcttat ttataacgat
    24841 taaaggggtg aaaagaatat gatgacaacg aaaattatac gtcgttatag tttaatcaca
    24901 atccttttaa ttgtgagtat attcataagt ttatgtgtag ggtctgtcat gattcatccg
    24961 attgatgcta ttaagggaat ctttgcacaa gatgatttta ttttaaatga gtatcgtata
    25021 cctagaacat tacttggtat tattatcggt agtagcttgg ctatatcagg tgcaattata
    25081 caagctgtaa taagaaaccc gttagcctca cctgatgtta taggtatttc taaaggtgcc
    25141 agtttagctg ctgtgattat tattatgatc tttccaacag caccattgtt tgtattacct
    25201 ataggttcat tcttaggtgc ctttgcagta agtttatttt tatcattttt aatttcaaaa
    25261 tatgatgtta aaggttcaaa gcttgcctta attggtttag caataggcgc aatatgtacg
    25321 gcgattgtgc agttcttatt aatcagaaat ccactggaag caaacaaagc gcttgtttgg
    25381 ttgacaggta gcctatatgg acatgatatg tcgaatattt atactatatt accttggttt
    25441 ttaataacga taccaatcat cattttattg agttatcaat tagatgtatt gaatctaggt
    25501 gatgctgttg caaccgcact cggtttaaaa gttaaaacta ttaaaatgct attgttaatt
    25561 ttagcagtaa tattagcagg atccgcaatt tcagttgtcg gtggtattag ctttttagga
    25621 ttaattgcac ctcatattgc gagacaatta ataggaaata aaacattaca cgttattatc
    25681 atgtcggggt taattggtgc tatattgtta acatttggag atggtttagc ccgtggcatt
    25741 catccgccac tggatattcc tgtaggggtt atcattgcaa ttatcggtgc accatacttc
    25801 ttaatattat tacgaagaat gaaataacta acatatgatt agagtttaaa aaaggttaag
    25861 tacgaaatca gtaattgtac ttaacctttt ttgaattcat cttgaaaaat tacaagaaat
    25921 agcgtatatt taataactgt aattattcat tattttgcat acataaacat tttaaaagat
    25981 agaatgataa ggaatatgtt tgttaactga atagaattct gtatatactt aaaacgaata
    26041 catagagaaa tggattgatt ttatggatag cttttcaagg aaagagatag ttattgggag
    26101 acttaagttt attacgatgt ctttaattgg tatcttatta tttttagtac caattccagt
    26161 cgaacaagat ggacagaagc aaacaacgtt gcccgtggca tttttagcag gcgtgcttaa
    26221 agatgtatta ggtggcgtaa tgccattttt aattgtgacg ataattactt tgtcgggtat
    26281 cataacactg atttgttcaa ctattttaaa agataaattg aaacctgacg ggctaatgaa
    26341 taatgctttt aacgttagaa ttggttggtt aattttgcgc ctacttgcag ttgtttttgc
    26401 atggatgaca tttttacgaa ttggttcaaa ggttatttac tcagatgaaa cgggtggatt
    26461 attgttctca agtttattgc caacattagt ggcagtattc ttatttgcag ctctattttt
    26521 accgctatta atggaatacg gtttgttaga gatgttgggt cctattttta gaccggttat
    26581 gagaccctta tttacattgc caggacgttc gacggtagat aatttagcct catttattgg
    26641 agacggaact gttggagtct taattacaag tagacaatat ggtgaaggat attattctcg
    26701 tcgtgaggca acagttattt caacgacatt tagtgtagtt tctatcacct tcgcaattgt
    26761 agttgctgaa acagtgcata tgcaaaatca attttttgct ttctatttat cagtgatagt
    26821 atcctgcctc gttgcagcag tcattatgcc aagaatttgg cctttaaata aaattcctga
    26881 tgagtatgct aaggaggtac ctgaaagtgc gcgtactgag gcattgccag aaggaaagac
    26941 ggcattgaga catggctttg atactgcaac agaagtaggt attaaagcac cgggcgttgt
    27001 tgactttttt aagtcaggat taaaaacagt cgttgatatg tggtttgtta ttttgcctgt
    27061 agtgatgagt attggtacta ttgctaccat tattgcgaac tacacgccct tttttgtcat
    27121 attgggtaaa ccttttgttc catttttaga gttaatgcaa atacctgaag cggcacaggc
    27181 ttctcaaacg attattatcg gtttcgccga tatgttttta ccttctatat taattgaagg
    27241 tgtacaaaat gatataactc gttttgttat tggggcactt agtatatcgc agttaatata
    27301 cttgtctgaa gtaggtggcg tcatacttgg ttcgaagatt cctgtaagca tcggcaaatt
    27361 gtttatgatt ttcttgatta gaacaatcat tacactacca attatttctt tgatggcaca
    27421 tcttttgtta taaatatatg tggaaaagga caactgttaa aattatggaa acagttgtcc
    27481 ttttgtattt gtttatgctg ggtgttgaac caattaaaaa aatcattcat gaagccctca
    27541 ccatgaatga tttttttata caatttattt agttaattca ttgtaaactt tttgatcgtt
    27601 ttgagtataa ataatgtatt cgtggtcttc agtatcgata ataacgcgat tcgttttacc
    27661 aaacgttgag ccgattctag atacatcttt gctgtctaat ttaggaactg catgaatatc
    27721 ttggtcttgt gtaatatttt taatttcact tgtaggaatt ttgatatcag caactctcca
    27781 ttgaatacgc acttcattat tatctttctt tactgtcatt gccattattc aaacacatcc
    27841 tttaaatatt ttgtaaatac atcataaacg attttgtaat cgttttcaag agttatgtga
    27901 tactttttta aattgtgtca tactaatgat ttttaacccg aaaatatgtt cgtgtttttg
    27961 ttagggatat ggtaaaatgt gagtattaaa ggagaacaaa tatgacaggt aaaacacatg
    28021 cttcatgcgg catgctcgtt ggagcgctaa caacacaata ttttcaaacg gatatttttt
    28081 cgtcggttac ggttatcatt ctagcaactc tagctagctt attacccgat atatgtcaca
    28141 ctcaaagtaa gattggcaga aggtttaagg taattagttt ttttgtgaga ttgatctttg
    28201 gacatcgaac ctttacgcat tcaatattat ttatcgcaat catagcattt ttattgcaaa
    28261 ttattcagac gcctaattac tatatggcag caattataat tggattagtg tcacatgtta
    28321 tactagatat gataacacca aaaggcgtga aattatttta tccgttaccg tttaatgtga
    28381 agacaccgat tcaatttaaa acaggtggac ttgtagactt atctttagct actgcgttaa
    28441 tggtcggaac agtttatgtt ttatttcagc ctttcatcaa tgatataata agcaactgga
    28501 atactaagtt tttatagaaa ataaattatt aaaggttaca aactcagcag gaggcataaa
    28561 atgctagata aaaatcaatt agctaaatat aaacaagatc atttgtgtga atatgaaaaa
    28621 ataatgagta acaatgaaaa agaagcactt gaagagaagg tagcgtcatt agatttagat
    28681 tttattgcca aattatataa cgatttatac atcaataaga aaacaataga tgatgtatct
    28741 gcagtttctg aagtgaaata tgatattaaa tcacaaatga gtgatgatga gattaagcgt
    28801 ttagagggac aaggacttca agctattaaa gaaggacaat ttgcagtact tttgatggca
    28861 ggtggacaag gaacaagact tggatataaa ggacctaaag gttcgtttga aattgaaggt
    28921 gtaagtttat ttgaacttca agctaaccaa ttaaaaacat tgaatcatca atctggacat
    28981 acgattcaat ggtatattat gacaagtgat atcaatcatg aagaaacttt agcttatttc
    29041 gaagcacata gttattttgg atatgatcaa gaagcaatcc atttctttaa acaagataat
    29101 attgtggcgc ttagtgaaga agggaagtta attttaaatc aacagggtcg tattatggaa
    29161 acgccgaatg gtaatggtgg cgtgtttaaa tctttagaca aggcaggata cttagaagaa
    29221 atgtctaata atggcgttaa gtatattttc ttgaataata tcgacaatgt tttagtaaaa
    29281 gtgttggatc cactatttgc aggatttacg gtagaacatg attacgatat tacttctaaa
    29341 acgattcaac caaaaccagg agaaagtgtt ggacgtttag ttaatgtcga ttgtaaagat
    29401 acagtactgg agtattcaga attagatcca gaagttgcaa atcaatttaa caatgctaat
    29461 atcggtattc atgcatttaa acttggtttt attttaaacg ctgtaaatcg tgaattacct
    29521 tatcatttag ctattaagaa tttgaaacaa ttagatgaga actttggtgt tattgaacaa
    29581 ccaactttaa aattcgaatt gttctatttt gacatattta cttatggaac tagttttgtc
    29641 acgttacaag ttcctagaga agaagaattt tcacctctta aaaatacaga aggtaaagat
    29701 agtgttgcaa ctgcaacaga agatttacgt agaatgggtt taatttaatg ataggcggtg
    29761 actatgatgt ccaaatctag tgaaaaaagt aatgacacaa ttgcagaaac atttaaggat
    29821 atcattccat tgtcatttgg agaagaaata ggcaatgctg catctcatgg gttagcagcg
    29881 ctgttaacac tattagtctt accttatgcg gctgtacata gttatattgc aaatggcaca
    29941 cttgcatcag ttagtatgtc aatttatgtt atttctatct ttatgatgtt tatttcatct
    30001 actatttatc attctatgca aaatgaaacg cctcataaat atattttaag gattattgat
    30061 catagtatga tttatgtagc aatatcaggt acatatacgc ctattttatt aacagttgta
    30121 ggtggttgga ttggatggac agtgtttatc ctattatggg gcacaacgct ttggggaatt
    30181 ttatataaat ccattgctgt caaagtaaac caaaagttaa gcttaattgt ctatttggta
    30241 atgggttggg taggtattat cttgctacca ataatattta ttcgtacatc ttggatattt
    30301 attttattta tttttctagg cggtgtgtca tatacgattg gtgcatggtt ctatgcacaa
    30361 aaaaacagac catattttca tatgatatgg catattttta tcgttatagc atcattattg
    30421 catttaattg caatcttata ttttatgtag tcgtttagaa aaggtggggg gaactccgct
    30481 ttttttatta cttaattcat tctaatagag gattgttttg ctttttttaa atcggtatga
    30541 tttttaaagc tgggagtgca cttaatttgt attaatcaga catttgatgg atacgtttat
    30601 ttgaattttt tagtaggtgc aacaaataga ttttttaaaa aactaatttg aatttaaaag
    30661 agggcaagat aggaaatagt aaaattagaa attacaaagc actatcatta ttataaaagg
    30721 aggtatagca tgcgtttaaa atcaattgta actgtaatag ctttaatatt aatcatgttt
    30781 atggctgcaa tcgaatcatc aattatttct ttagcgttac caacaattaa gcaagattta
    30841 aatgcaggga atttaatttc attgatattt acggcttact ttattgcatt agtgattgcg
    30901 aatccaatag taggtgaatt attaactcga tttaaaatta tttatattgc tatcgcaggt
    30961 cttacactat tcacggttgg tagtttaatg tcaggtttaa gcacacattt tagtatgttg
    31021 attatatcac gtgtaattca agggtttgga tctggtgtca tgatgtcctt gtcgcaaatt
    31081 gtgcctaaac tagcgtttga aattccatta cgctataaaa taatgggtat cgttggtagc
    31141 gtttggggga tttcaagtat cattggtccg ttactaggag gcggtatact tgaatttgca
    31201 acttggcatt ggttattttt tattaatatt ccgatagcaa ttattgcaat aatattggtt
    31261 gtctggacat ttcatttttc agaagaagaa actgtggcta aatcaaaatt cgatactaaa
    31321 ggtatcacct tgttttatat tttcattggt ttaattatgt ttgcattgtt aaaccaacag
    31381 catctatatt taaatatcat aggttttgtt ttagcaatat taattgcact tcgattattt
    31441 aatgttgaga aaaaagtttc atccccattc ttaccagtag cagaatttaa tcgaatgatt
    31501 actttggtct ttattacaga tcttcttaca gctgtttgtt taatgggctt taatttatat
    31561 attcctgtgt atcttcaaga acaactggga ttatcgccat tgcaaagtgg attagttatt
    31621 tttccacttt ctgtagcgtg gattacattg aattttaatt tgcaccatat tgaagcgaag
    31681 ttatcaagaa aagttatcta tttgtcgtct tttacattat tattattaag tagtataatc
    31741 attgcgtttg gtataaaatt accaatcctt atagcatgtg tcttaatttt aagtggaata
    31801 agctttggat atatttatac aaaagatagt gtaattgtcc aagaggaaac aagtccaata
    31861 caaatgaaga aaatgatgtc gttttatgga ttaacaaaaa accttggcgc atcaataggt
    31921 tcgacgatta tgggatacct ttatgcatta aaatcaggat tatttggtgc aaacttgcat
    31981 aatattttag gcgttgtatc cttgataagt gtagggctca tcgttgtatg gctcatattt
    32041 tatagagaag cggcgtcaca aacaaatgaa tagaattatc attaaaattg atgtagtgta
    32101 aataaagtaa gaaataatca ttttactagg tttgaagtgt aatcaactat cttaaaatga
    32161 aaagcaatat aaattattta tggtaaggag gacaatagtt atgaattatc ttaaacataa
    32221 gttttataat ttattaacaa caattattgt tctctttatc tttgtgcttt ctggtgcgat
    32281 atttttaacg tttttaggat tcggactata tggattaagt agaattctta tttattttag
    32341 gttaggtgac ttcacatata acagaagtat gtacgacaac ctattgtatt atggcagtta
    32401 tataatcttt gggtacttca tcatatttgc agtcgagcat ttaatggatt attttagaaa
    32461 aatgttacct gaaaatgctt attttagagg tgcaactttt catttaatct cttatatggt
    32521 tgcaacaacg ttattttatt ttattattca tctgaactat gtatatatca atattgattt
    32581 ttgggtcatc atggttatta taggcttttt atatgtttgt aagttgcagt tttaccctga
    32641 aagtaaaaat ctaaacaata gaaaatagag ttttgaagtt gggggcaatg atgtgttcca
    32701 acttcttttt attcatatag tagaaaatga gttgttttgc ttcaattaat cacggttaat
    32761 aataaccatt gatataaata gttggtactg taatctgaaa tatattttaa gtatatatgc
    32821 taataaacgt aaatttgtta caaaggagga attgtggtgg ctaatgttga attaacaacg
    32881 cgaagacgaa attttatagt agctgtgatg ttaatcagtg cttttgtagc tattttaaat
    32941 caaacattat taaatacagc gttacctagt attatgagag agttaaatat caatgaaagt
    33001 acttcacaat ggttagttac tggttttatg cttgttaatg gcgtcatgat acctctaact
    33061 gcatacttaa tggacaggat taaaactaga cctttatact tagcagcgat gggaacattt
    33121 ttattaggtt ctattgttgc agccttagct ccgaattttg gagttttaat gttagcacgt
    33181 gtaattcaag cgatgggtgc aggggtactt atgcctttaa tgcaattcac attgtttacg
    33241 ttattcagta aagaacatag aggatttgca atgggattag ctggtttagt tattcaattt
    33301 gcaccagcaa ttgggcctac tgttactgga ttaatcattg atcaagcaag ttggcgtgta
    33361 ccttttatta taattgtagg aattgcttta gtcgcattta tcttcggttt aatttcaatc
    33421 tctagttaca atgaagtgaa atatacgaaa ttagataagc gctctgtaat gtattcgacg
    33481 attggatttg ggttaatgtt atatgcattc agtagtgcag gcgacttagg atttactagc
    33541 ccgatagtta taggtgcatt gataataagt atggttatta tctatttatt tatacgtaga
    33601 caatttaata ttagtaatgc acttttaaat ttaagggttt ttaagaatag aacatttgca
    33661 ttatgtacga ttagttcaat gattataatg atgtcaatgg ttggacctgc actgcttata
    33721 ccgctatatg ttcaaaatag tttgtcttta tctgccttgt tatcaggact tgttatcatg
    33781 ccaggtgcaa tcataaatgg tattatgtcg gtttttacag gtaaatttta tgataagtat
    33841 ggtcctagac cactgattta tactggtttt acgattttaa caattactac tattatgttg
    33901 tgtttcttgc atacagacac atcttatacg tatttaatag tcgtatatgc aattagaatg
    33961 ttttcagttt ctttactcat gatgccgata aatactacag gaattaattc tttgagaaat
    34021 gaagaaatct cacatggcac ggctattatg aactttggtc gtgtaatggc tggttcacta
    34081 ggcacagctt taatggttac tttgatgagt tttggcgcaa aaatattttc atctacatcg
    34141 ccatcgcatt taactgcaac tgaaattaaa cagcaatcaa ttgctatagg ggtggatatc
    34201 tcatttgctt ttgtagccgt gcttgttatg gcagcttatg tgatagcact ttttataaga
    34261 gaacctaaag aaatagaaag taatagaagg aaattttaaa ataattatag tagttggtct
    34321 attgaaaata ataggctaac ttcttttttt atttaataaa aagttttata cttttagtga
    34381 tagactaagc aaaaattgtt atttgctatg atgtagatgt cttaaaatga ttaaggggga
    34441 tttgctttgt taacggtaga tcaagtgaaa gaattggtag gagaaattaa agaccctatt
    34501 atagatgtgc ctttaaaaga aacagaaggt attgttgaag tttctattaa ggaagaaaaa
    34561 gaacatgtga gtgttaaatt agcaatggca caattaggtg gtgcaccgca attagattta
    34621 caaatggctg ttgttaacgt attaaaagaa aacggtgcga aaacggtcgg tatacgattt
    34681 gaaacattgc cggaagaaaa agtaaatcaa tttaaaccaa aagaagaaaa taaacctaaa
    34741 acgatagaag gcttattatc tcaaaataat ccagtcgaat ttattgctat tgcttcaggt
    34801 aaaggtggcg tcggtaaatc cactgttgca gtaaatttag ccgttgcctt agcccgtgaa
    34861 gggaaaaaag tcggattagt agatgccgat atatatggat ttagtgtacc agatatgatg
    34921 ggtattgatg aaaaacctgg aattaaaggg aaggaagtaa ttccagttga acgtcatggc
    34981 gttaaagtta tatcaatggc cttttttgtg gaagaaaatg cgccagttat atggagaggg
    35041 ccaatgttag gtaaaatgtt gacgaatttc tttacagaag ttaaatgggg agacattgaa
    35101 tatttaatac tcgatcttcc acctggaaca ggagatgtag ctttagatgt tcatacgatg
    35161 ttaccttcaa gtaaggaaat tattgtaacg acacctcatc ctacagcagc atttgttgca
    35221 gctcgcgcag gtgcgatggc aaaacatacg gatcattcta ttcttggcgt aattgaaaac
    35281 atgagttatt ttgaaagtaa agagacgggt aataaagaat atgtctttgg caaaggtggc
    35341 ggtactaagt tagctgatga acttaatact caattacttg gggaattacc tttagagcaa
    35401 ccatcttgga atccaaaaga ttttgcaccg tcaatatatc aatcagatga tcgtctaggt
    35461 aaaatttata gctcgattgc acaaaaagtt atagctgcta caaataaata ggtataatat
    35521 atgctaaacg tacaaaatta cttttatttt gtacgttttt atgttgattt gttttggaat
    35581 gctggtaaaa taagttcttg tgttaagcaa taaacgcgtt gaaaaagaag cgggttgtga
    35641 acacaaaaag tttttaaaaa agttattgac tttaaattcc aaagttgata atatgataaa
    35701 gtcgtcaaaa acgacgcagt tgtttttaaa gaagaatttc aaaagtgtaa aacttaccat
    35761 tgaaataact ataaaaacaa tatagaataa ataaagtaat cgttcaaaaa gttattgact
    35821 tcaagaaaca aatgaagtag aataaaagag attgaacat
//
LOCUS       DAPSKH010000027        35208 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPSKH010000027 DAPSKH010000000
VERSION     DAPSKH010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 35208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35208
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.027"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..277
                     /gene="sarU"
                     /locus_tag="RPH49_001340"
     CDS             <1..277
                     /gene="sarU"
                     /locus_tag="RPH49_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarU"
                     /protein_id="HDY5124501.1"
                     /translation="LTFLDLSILYVISSRKNEILNLKDLFESIRFMYPQIVRSVNRLN
                     NKGMLIKERSLADERIVLIKINKIQYNTIKSIFTDTSKILKPRKFFF"
     gene            complement(489..1355)
                     /gene="galU"
                     /locus_tag="RPH49_001341"
     CDS             complement(489..1355)
                     /gene="galU"
                     /locus_tag="RPH49_001341"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDY5124502.1"
                     /translation="MKKIKKAIIPAAGLGTRFLPATKAMPKEMLPILDKPTIQYIVEE
                     AARAGIEDIIIVTGRHKRAIEDHFDSQKELEMVLKEKGKSELLEKVQYSTELANIFYV
                     RQKEQKGLGHAISSARQFIGNEPFAVLLGDDIVESEVPAVKQLIDVYEETGHSVIGVQ
                     EVPEADTHRYGIIDPLTKNGRQYEVKKFVEKPAQGTAPSNLAIMGRYVLTPEIFDYLK
                     TQKEGAGNEIQLTDAIERMNNDNQVYAYDFEGERYDVGEKLGFVKTTIEYALKDDSMR
                     EELTRFIKELGL"
     gene            complement(1535..4408)
                     /gene="fnbB"
                     /locus_tag="RPH49_001342"
     CDS             complement(1535..4408)
                     /gene="fnbB"
                     /locus_tag="RPH49_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein FnbB"
                     /protein_id="HDY5124503.1"
                     /translation="MKSNLRYGIRKHKLGAASVFLGTMIVVGMGQEKEAAASEQNNTT
                     VEESGSSATERKASETQTTTNNVNTIDETQSYSATSTEQPSQSTQVTTEEAPTTVQAP
                     KVETSRVDLPSEKVADKETTGTQVDTAQPSNVSEIKPRMKRSTDVTAVTEKEVVEEAK
                     ATGTDVTSKVEVEEGSEIVGHNNKETNVVNPHNAERVTLKYKWKFEDGIKPGDYFDFT
                     LSNNVETHGISPLRKVPDIKSKDDNILAVGKVMDERKIRYTFTDYINNKNNLMAELNL
                     NLFIDPTTVTKQGKQTVEVKLGENKISKEFDIKYLDGVKDNWGVTVNGRITLLDKENS
                     KIHHLAYINPKKSDMTSITINGFFAKGGLYTGNVPTVKVYEYLRSDELPESVYANTND
                     QEKFKDVTNDMSDKLTLSENGSYKLTLDALNKKSYVVSFEGKYNENDKELLFRTNLHG
                     YHANYGYYYYYPVSLTWDNGVAFYSNNAQGDGKDKPNDPIIEKSEPIELDIKSEPPVE
                     KHELTGTIEESNDSKPIDFEYHTAVEGVEGHAEGIIETEEDSIHVDFEESTHENSKHH
                     ADVVEYEEDTNPGGGQVITESNLVEFDEESTKGILTGAVSDHTTVEDTKEYTTESNLI
                     ELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSE
                     LGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIHGQNKGDQSFEEDTEK
                     DKPKYEHGGNIIDIDFDSVPHIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVEYEEDTL
                     PQVSGHNEGQQTIEEDTTPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSE
                     PETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKA
                     QSKKSELPETGGEESTNKGILFGGLFSILGFALLRRNKKNHKA"
     gene            complement(5089..8136)
                     /gene="fnbA"
                     /locus_tag="RPH49_001343"
     CDS             complement(5089..8136)
                     /gene="fnbA"
                     /locus_tag="RPH49_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein FnbA"
                     /protein_id="HDY5124504.1"
                     /translation="MKNNLRYGIRKHKLGAASVFLGTMIVVGMGQDKEAAASEQKTTT
                     VEENGNSATENKVNETQTTTTNVNTIDETQSYSATATEQPSNATQVTTEEAPKAVQAP
                     QTAQPANLETVKEEVVKEEAKPQVKETTQSQDNSGDQRQVDLTPKKATQNQVAETQVE
                     VAQPRTASESKPRVTRSADVVEAKEASDEKVETGTDVTSKVTVESGSIEAPQGNKVEP
                     HAGQRVVLKYKLKFADGLKRGDYFDFTLSNNVNTYGVSTARKVPEIKNGSVVMATGEI
                     LGNGNIRYTFTNEIEHKVEVTANLEINLFIDPKTVQSNGEQKITSKLNGEETEKTIPV
                     VYNPGVSNSYTNVNGSIETFNKESNKFTHIAYIKPMNGNQSNTVSVTGTLTEGSNLAG
                     GQPTVKVYEYLGKKDELPQSVYANTSDTNKFKDVTKEMNGKLSVQDNGSYSLNLDKLD
                     KTYVIHYTGEYLQGSDQVNFRTELYGYPERAYKSYYVYGGYRLTWDNGLVLYSNKADG
                     NGKNGQIIQNNDFEYKEDTAKGTMSGQYDAKQIIETEENQDNTPLDIDYHTAIDGEGG
                     YVDGYIETIEETDSSAIDIDYHTAVDSEAGHVGGYTESSEESNPIDFEESTHENSKHH
                     ADVVEYEEDTNPGGGQVTTESNLVEFDEESTKGIVTGAVSDHTTIEDTKEYTTESNLI
                     ELVDELPEEHGQAQGPIEEITENNHHISHSGLGTENGHGNYGVIEEIEENSHVDIKSE
                     LGYEGGQNSGNQSFEEDTEEDKPKYEQGGNIVDIDFDSVPQIQGQNNGNQSFEEDTEK
                     DKPKYEQGGNIIDIDFDSVPQIHGFNKHTEIIEEDTNKDKPNYQFGGHNSVDFEEDTL
                     PKVSGQNEGQQTIEEDTTPPTPPTPEVPSEPETPTPPTPEVPSEPETPTPPTPEVPSE
                     PETPTPPTPEVPAEPGKPVPPAKEEPKKPSKPVEQGKVVTPVIEINEKVKAVAPTKKA
                     QSKKSELPETGGEESTNKGMLFGGLFSILGLALLRRNKKNNKA"
     gene            complement(8120..8222)
                     /locus_tag="RPH49_001344"
                     /pseudo
     CDS             complement(8120..8222)
                     /locus_tag="RPH49_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501263.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8605..9963)
                     /locus_tag="RPH49_001345"
     CDS             complement(8605..9963)
                     /locus_tag="RPH49_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease"
                     /protein_id="HDY5124505.1"
                     /translation="MFNEIWPLISVVLGIVILLVLIIGFKLNTFISLIITSMITALML
                     GIPLTKIMETIEKGMGSTLGHIALIFGLGAILGKLLADGGGATRIADTLIQKFGQKHV
                     QWAMLVAAFIVGIALFFEVGLVLLIPLVFTVAKRANVSVLKLGLPMVTALSVTHGFLP
                     PHPGPVVIAKELKANVGDVLLYGMIIAIPVTLIAGPIFNKVAQKMIPSAYTREGDISA
                     LGAQKEFTDQEMPGFGMSLLTATLPVILMLVSTITQLVTGHDKPTNLFESIIYMIGTA
                     GTAMLIAVLFAIVTMGLMRKRKMNHIMESVTNAIYPIGMMLLIIGGGGTFKQVLIDGG
                     VGNTIAKMFEGTEMSPILLAWIVAAVLRIALGSATVAAISTTGIVLPLLQSSDVNVAL
                     VVLAIGAGSVILSHVNDAGFWMFKEYFGLTVKETFLTWSLLETIISVSGIIFILFISL
                     FV"
     gene            complement(10080..11633)
                     /gene="gntK"
                     /locus_tag="RPH49_001346"
     CDS             complement(10080..11633)
                     /gene="gntK"
                     /locus_tag="RPH49_001346"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDY5124506.1"
                     /translation="MKYMIGVDIGTTSTKSVLYDDNGTFIMKHQIGYDLHTPNVDVSE
                     ENPDELFDAVLMTIKYVMRESKVNKDDIKFVSFSAQMHSLIAMDQKHQRLTNNITWAD
                     NRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKT
                     YIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMLPELVPTTYVMKGM
                     KERYATLMGLNEDTPFVIGASDGVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTD
                     YKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAKRLGVDPYDVLTQIA
                     KRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYT
                     VYLALIEVMNETPKMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGL
                     KAVGDIEDFSIVSSMVGATNNHMPFEENVAVYQELVSIFINLSRSLTENYEQIADFQR
                     QHMAENKTQ"
     gene            complement(11657..12337)
                     /locus_tag="RPH49_001347"
     CDS             complement(11657..12337)
                     /locus_tag="RPH49_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5124507.1"
                     /translation="MMYGYPEKWLEGMTTGEGIAAELRLGIVNGHIAEGTLLTENQMA
                     KQFNVSRSPIRDAFKLLQQNQLIQLERMGAHVLPFGEQEKKEMYDLRLMLESFAFSRV
                     KNQERLPIVKEMKKQLEMMKVAVKFEDAESFTKHDFEFHETLIKASNHQYLNSFWSHL
                     KPVMMALVLTSMRQRMQQNPQDFERIHHNHQVFIDAVEQYDSQILKEAFHLNFDDVGK
                     DIEGFWLN"
     gene            complement(12491..13255)
                     /locus_tag="RPH49_001348"
     CDS             complement(12491..13255)
                     /locus_tag="RPH49_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDY5124508.1"
                     /translation="MSNYSTGELAKLCNVTTRTIQYYDRKGILKPQGFTEGKRRVYTE
                     QQRQTLELILLLKDLGCALSDIDMLLKGEGTLKTLNTLLTMKQQEINQQVKQQQAVLN
                     KIKNVQYYVNKASTSPITHLKDIEHVMSKSAEMKSIRRNIWISAGIIGIIQYSSIISA
                     ILMKNKWPFLIALPFMIGYGIGVTFYYQQKVAYLCPNCQHIFSPSLWAVIKAKHTATT
                     RRFECPNCHETHYCIEVPKAHMSTEQLEISRIQHNN"
     gene            complement(13420..14112)
                     /locus_tag="RPH49_001349"
     CDS             complement(13420..14112)
                     /locus_tag="RPH49_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDY5124509.1"
                     /translation="MYVDRKPSLYLEDLRHDFKNSLSKFENGDEAFDTLLGFVELDHI
                     YSSALKEISTKLSILDDNFNHIYKHNPIHHMERRVKEMRSLIEKLNRKGLQISAETAK
                     EHILDIAGIRVVCNYLDDIYLIEEMLLKQEDVQLIKRKDYIQHPKENGYRSLHIVVSI
                     PVFLAERVEVLPVEIQIRTIGMDMWASLEHKIRYKNNAETEKYRDLLKECATEITEVE
                     DKLQQIHSEITE"
     gene            complement(14343..14759)
                     /locus_tag="RPH49_001350"
     CDS             complement(14343..14759)
                     /locus_tag="RPH49_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDY5124510.1"
                     /translation="MPFTMKGYPEKWKDFEVIKRQKAIEIANAMLKEGYLEKDVVPIA
                     AKKAKDWYRALSKEEIKALEEENFVQFHTATMEKTEVDSEYATTDNEEHIQEQSNQDK
                     SYFDSESIGNQSGGVRQREPLMDGPHPKVVESFKDV"
     gene            complement(14898..16721)
                     /locus_tag="RPH49_001351"
     CDS             complement(14898..16721)
                     /locus_tag="RPH49_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDY5124511.1"
                     /translation="MIIPAIIGYLCGNFQFGLLVATGTLAHIYVFKGPSRSKLRTVII
                     CNLAFAICMMLGTLTAKTPLVFGMTLLIVTVIPFYIFTALKIAGPSSTFFIVTFSLPI
                     NLPIAPEEALYRGFAILVGGILATMMVLITIVFSKNKAEEQAIQNDFKLISKLLHTYN
                     DKSAFLQVAKTAVDNFKASDKLLITSTSSNDKLSRRFQKLLLLHTSAQGIYSELLELN
                     AKQIRPLPDELIEMMDHIIAQLDNSEENVRYWRKEVTVTEEFQNLFNHILKIDEMVHA
                     NEARIAYEADMRKPLYSKRIYQNLTLDSIVFRNTLRYTAIMMIAIFIALMFDFEKAYW
                     IPLSAHTILLGTSTIHAIERGMARGLGTILGVLVLSVILLFSIPTPVAVILMGIAALF
                     TEALVGANYAIAVVFITIQVILMNGLASQNLTINIAFPRVIDVAMGIVIAIIGLFVLG
                     QRTASALLPNVMAEVVRKEATLFHYLFSENQYKDDVYQKNTAMNLSVKLNNMTQVYNA
                     ANGELFSDKTLIQNYYPSLFALEEISFMLNRAMANEDRLTINEQLMGEYLATFENIAK
                     HLELNTELEIKILPDLPQYNYIQSAMMNIQHNSFCERDKNV"
     gene            complement(17631..18908)
                     /locus_tag="RPH49_001352"
     CDS             complement(17631..18908)
                     /locus_tag="RPH49_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124512.1"
                     /translation="MKEKRTNVRWMFALAFFFIGVIAYMDRANISYIAKQMMDDLGMT
                     KPQFGLLASFFSLGYALMQVPSGMLAEKFGPRKMITIALVWWSAFTILTGMIKNHGLI
                     YLVRFLFGVGEAPMYPSNAVFNSFWFSKNEKGRASSALLAGSYFGPVLAPIVTIAIVN
                     AFNWQAVFYIFGAVGILMAVLWAIIAKDLPEQHRMVNEAEKRFIMENRDIVATEKSSP
                     PWNDFFKRFSFYAIAIQYFVVQFIITLFLIWLPTYLTEVFHVNFKEMSISSLPWLLMF
                     FLILSAGAISDRVLGLGRSKFVARGVIAIAGFIVFAVSIIFAVRTGNLYVSIFWLSLG
                     LGGIGISMGMSWAAATDLGRNFSGTVSGWMNLWGNIGALISPLLAGLFVEHLGWTMTF
                     QLLIVPAVIAVIMWFYVKPDQPLIVSDDKAIEK"
     gene            19455..20066
                     /locus_tag="RPH49_001353"
     CDS             19455..20066
                     /locus_tag="RPH49_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDY5124513.1"
                     /translation="MEQIITEFISRFGYAAIFILILLENVLPIVPSEIILTFAGLMSV
                     KSHLSILTLFIIATIASFIGLLILYYICRLISEERLYRFIDRHGKWIKLKSKDLKRAN
                     DWFKKYGVWAVFICRFIPVLRVLITIPAGVNRMNVVTFTVISLIGTTIWNFGLILLGR
                     TLSDSFGMLMTGLHTYSRIMYVIIIIAVIYFAIRYIGKRKRVK"
     gene            complement(20075..20174)
                     /locus_tag="RPH49_001354"
                     /pseudo
     CDS             complement(20075..20174)
                     /locus_tag="RPH49_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501275.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(20164..21327)
                     /locus_tag="RPH49_001355"
     CDS             complement(20164..21327)
                     /locus_tag="RPH49_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124514.1"
                     /translation="MTNSNIRLYILGFLAFFASLIQNIYTPIIPRLYDDFQVPLFWIN
                     ATVGGFIFIVAVMQIVLGRSIDSRDSKKVLLTGLGIVIISSFICAMTHNFILFAISRL
                     FQAIGCGIIPLVTLTLLAKLSTDNGRAQAMANYQIFLSCAPALAPILGSTLGARWDYI
                     GIFSFLLVISIVLFLIIFFIDIPNVEKGIVKLTEKIEEKYLIDKVFITLVTLGFLIFL
                     TYFSILVYLPTLLNNTYDIGVGISGVLFLPITVSVILGSLFYKRLSKKYNEIMILRVT
                     ITGFAIFTLLFGWLNESNVIILSVIIFILGTCVGIVPALLSTIISKRFEHIKGKVLGV
                     FNFVRYIGMTVGALLIGIISHSLVPFYFTTVTIMLIIIFLYIKIGDFQLKFAK"
     gene            complement(21320..21640)
                     /locus_tag="RPH49_001356"
                     /pseudo
     CDS             complement(21320..21640)
                     /locus_tag="RPH49_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501277.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix DNA-binding protein"
     gene            22054..22749
                     /locus_tag="RPH49_001357"
     CDS             22054..22749
                     /locus_tag="RPH49_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDY5124515.1"
                     /translation="MDVLTIEHLTKKIGNKTILEDVSFKLKRGQIVGLVGANGAGKTT
                     LMKVILGYSSFQSGNFNVINSKDSKSNIGALIENPGIYPFMSGYENLKLLNESKNTQD
                     IDKIVSQLHMDEYIHKKAKTYSLGMKQKLGIAIAFLNKPQFIILDEPMNGLDPKAVRD
                     VRELIVQKAQEGVTFLISSHILSELVKITNSILIINKGKIVTETSEEELKQFKDNDLE
                     NVLLEIIEREDQA"
     gene            22751..23521
                     /locus_tag="RPH49_001358"
     CDS             22751..23521
                     /locus_tag="RPH49_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124516.1"
                     /translation="MGTLIKQECFKLFKKKSTFIAPIVFILLMVAQGYIATKYNEIFT
                     PQESFTSAYNGFSWFAFLLIIQASTIISMEFHYGTIKNLLYREYSRTTMIVSKIITLF
                     IISLIYFVITIIASIVIGSLFFNDLNIFESSGNQLSLLNQLLLVSLGTFVGVWLVLSL
                     TLLLSSATNSTGVAIAVGIVFYFASSILAVIQTALLEKIDWLKWNPINMMNIMLQTVE
                     KGFSKSTKLELHELFIGNIAYISIFLILVVFIFKKKNI"
     gene            23958..25922
                     /locus_tag="RPH49_001359"
     CDS             23958..25922
                     /locus_tag="RPH49_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1,6-bisphosphatase"
                     /protein_id="HDY5124517.1"
                     /translation="MTQITERELKKKYLDLLSQHFDTPEKLATEIINLESILELPKGT
                     EHFVSDLHGEYEAFQHVLRNGSGNVRAKINDIFKDKLSTKELNDLTALVYYPEDKLQL
                     IKCDFQNYGQLNVWYITTIEHLIQLIKYCSSKYTRSKLRRALPEQYVFIVEELLYKNN
                     EFKNKKSYYETLVNQVIELKQADDLIIGLAYSVQRLVVDHLHVVGDIYDRGPQPDKIM
                     DTLINYHSLDIQWGNHDVLWVGAYAGSKVCLANLLRICARYDNLDIVEDAYGINLRPL
                     LTLAEKYYDADNPAFKPKKRPDKHERLTQREESQITKIHQAIAMIQFKLEIPVIKRRP
                     NFEMDERLVLEKVNYDTNEITVYGKTYPLKDTCFQTVNRDNPAELLPEEEEVMNKLLL
                     SFQQSEKLRRHMSFLMRKGSLYLPYNGNLLIHGCIPVDENGEMESFEIDGQTYSGQEL
                     LDVFEYHVRKSFDEKENTDDLSTDLVWYLWTGKYSSLFGKRAMTTFERYFIADKASHK
                     EEKNPYYHLREDVNMVRKMLSDFGLNPDEGRIINGHTPVKEINGEDPIKADGKMLVID
                     GGFSKAYQSTTGIAGYTLLYNSFGMQLVAHQQFNAKEKILSEGIDELSIKRIVDKELQ
                     RKKIRNTNKGKELQAQIDILKMLMHDRYLD"
     gene            26264..27343
                     /locus_tag="RPH49_001360"
     CDS             26264..27343
                     /locus_tag="RPH49_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124518.1"
                     /translation="MRILKESIIVAFAFVGVVVGAGFATGQEIFQFFTSHGVYSISGI
                     IVTGLLITLGGMIVMHTGHHLKSRNHSDSINYFLYPSIARGFDIILTMFMLSLAIIMT
                     AGGASTIHQSFNLPYWLSALILVAFILATLFLKFDRLIAVLGGVTPFLIAIVIMIAVY
                     YFTTSHLDFTAANNDAQIHKQKSLSPGWWFDAINYASLQIAAAFSFLSVMGSKVKYRD
                     STLYGGLIGGLIITFLLMMINLGLISQFDKIKHVDLPTLKLATQMSPSIGIIMSVIMI
                     LVIYNTVVGLMYAFASRFSVPFSRRYFIIIITMAVITYISTFIGFISLIGKVFPIMGL
                     FGFILLIPVLYKGLIKRITGKSHID"
     gene            complement(27448..28041)
                     /locus_tag="RPH49_001361"
     CDS             complement(27448..28041)
                     /locus_tag="RPH49_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5124519.1"
                     /translation="MEHIFREGQKGAPTLILLHGTGGDEFDLLPLGEALNENYHLLSI
                     RGQVSENGMNRYFKRLGEGVYDEEDLAFRGQELLTFIKEAAERYEFDIEKAVLVGFSN
                     GSNIAINLMLRSEAPFKKALLYAPLYPIEVTSTKNLSDVSVLLSMGKHDPIVPLAASE
                     QVINLFKTRGAQVEEVWVNGHEITETGLTAGQQILGK"
     gene            complement(28063..29031)
                     /locus_tag="RPH49_001362"
     CDS             complement(28063..29031)
                     /locus_tag="RPH49_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000183732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDY5124520.1"
                     /translation="MANNHELLGIHHVTAITDNAERNYKFFTEVLGMRLVKKTVNQDD
                     IYTYHTFFADDVGSAGTDMTFFDFPDIPKGQAGTNSITRPSFRVPNDDALTYYEQRFD
                     EFGVKHEGIQELFGKKVLPFEEVDGQVYQLISDELNEGVAPGVPWKNGPVPVDKAIYG
                     LGPIEIKVSYFDDFKNILETVYGMTTIAHEDNVALLEVGEGGNGGQVILIKDDKGPAA
                     RQGYGEVHHVSFRVKDHDAIEAWATKYKEVGINNSGIINRFYFEALYARVGHILIEIS
                     TDGPGFMEDEPYETLGEGLSLPPFLENKREYIESEVRPFNTKRQHD"
     gene            complement(29109..29543)
                     /locus_tag="RPH49_001363"
     CDS             complement(29109..29543)
                     /locus_tag="RPH49_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5124521.1"
                     /translation="MDRTKQSLNVFVGMNRALDTLEQITKEDVKRYGLNITEFAVLEL
                     LYNKGPQPIQRIRDRVLIASSSISYVVSQLEDKGWITREKDKDDKRVYMACLTEKGQS
                     QMADIFPKHAETLTKAFDVLTKDELTILQQAFKKLSAQSTEV"
     gene            29770..30054
                     /locus_tag="RPH49_001364"
     CDS             29770..30054
                     /locus_tag="RPH49_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDY5124522.1"
                     /translation="MSNLEIKQGENKFYIGDDENHALAEITYRFVDNNEINIDHTGVS
                     DELGGQGVGKKLVKAVVEHARENHLKIIASCSFAKHMLEKEDSYQDVYLG"
     gene            30228..31034
                     /locus_tag="RPH49_001365"
     CDS             30228..31034
                     /locus_tag="RPH49_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5124523.1"
                     /translation="MAFHDKTATQVTNIELNVRDLDLMTTFYKNILGLSVKSSDDNTT
                     VLSVGTGGHTLTLHLLEDGRQTSPREAGLFHIAFLLPTTEDLANFLYFVAQKNMGIGA
                     GDHLVSEALYFNDPEGNGIEVYRDRPSSSWEWQNGKVKMDTLEVDSQTLLTHRTDEGW
                     QGMPAKGMIGHLHLKTHDLDAAYQCYIEQLGFQHVSDFPRALFMSTNHYHHHIAANTW
                     QSNQARQNNAQSYGLTHVDIYQPDASTHTFTAPEGFGITVHSNTDLVPEK"
     gene            complement(31154..31825)
                     /locus_tag="RPH49_001366"
     CDS             complement(31154..31825)
                     /locus_tag="RPH49_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDY5124524.1"
                     /translation="MSNMNQTIMDAFHFRHATKQFDPQKKVSKEDFETILESGRLSPS
                     SLGLEPWKFVVIQDQALRDELKAHSWGAAKQLDTASHFVLIFARKNVTSRSPYVQHML
                     RDIKKYEAQTIPAVEQKFDAFQADFHISDNDQALYDWSSKQTYIALGNMMTTAALLGI
                     DSCPMEGFSLDTVTDILANKGILDTEQFGLSVMVAFGYRQQDPPKNKTRQAYEDVIEW
                     VGPKE"
     gene            32095..33087
                     /locus_tag="RPH49_001367"
     CDS             32095..33087
                     /locus_tag="RPH49_001367"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDY5124525.1"
                     /translation="MTKIMFFGTRDYEKEMALNWGKKNNVEVTTSKELLSSATVDQLK
                     DYDGVTTMQFGKLENDVYPKLESYGIKQIAQRTAGFDMYDLDLAKKHNIVISNVPSYS
                     PETIAEYSVSIALQLVRRFPDIERRVQAHDFTWQAEIMSKPVKNMTVAIIGTGRIGAA
                     TAKIYAGFGATITAYDAYPNKDLDFLTYKDSVKEAIKDADIISLHVPANKESYHLFDK
                     AMFNHVKKGAILVNAARGAVINTPDLIAAVNDGTLLGAAIDTYENEAAYFTNDWTNKD
                     IDDKTLLELIEHERILVTPHIAFFSDEAVQNLVEGGLNAALSVINTGTCETRLN"
     gene            33495..33975
                     /locus_tag="RPH49_001368"
                     /pseudo
     CDS             33495..33975
                     /locus_tag="RPH49_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(34186..34986)
                     /locus_tag="RPH49_001369"
     CDS             complement(34186..34986)
                     /locus_tag="RPH49_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5124526.1"
                     /translation="MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASG
                     NQYAKLKSIFGDRDMYFISENGAVIYKGNELYNYKSFNRQVFQQVVDYLNMNQGIDQL
                     VICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
                     DEEVATQFSNDIKLVSSGHDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANND
                     KDMLAFAKHSYVMENSHDEELFNIASAVAPSNDKQGVLTIIEQEVLNK"
BASE COUNT        10887 a         6529 c         5212 g        12580 t
ORIGIN      
        1 tttaacattt cttgatttat ctatcttata tgtaatatca tctcgaaaaa atgagatact
       61 aaatttaaaa gatttgtttg aaagtattag atttatgtat cctcaaattg ttaggtcagt
      121 taatagatta aataataaag gtatgctaat caaagaacga tcccttgcag atgaaaggat
      181 tgtgttaatc aaaataaata aaatacaata taacactatt aaaagcatat tcacagatac
      241 ttccaagatt ctcaaaccaa gaaaattttt cttttaaatt taaacagatt tacctcttga
      301 taaaataaat aagcaatcat aatacttctc aatttagtat aaataaaaat acataattaa
      361 ctttcttttg tttttatatt atttcaatac cctactatat atcacaacac ataaattaag
      421 catgacactc attcaattta gttcacaatt tcgtgttcca attttattga gtatcatgct
      481 ttttaatgtt ataaccctaa ttctttaata aatcgtgtta attcttctcg catactgtca
      541 tctttcaatg catattctat cgttgtttta acgaagccta atttttctcc aacgtcataa
      601 cgttcgcctt cgaagtcata tgcatacact tggttatcat tattcatacg ttcaatcgca
      661 tctgttaact gaatttcgtt acctgcgcct tctttttgcg tttttaaata atcgaaaatt
      721 tcaggcgtta atacataacg tcccataata gctaggtttg atggtgccgt accttgtgct
      781 ggcttttcaa caaacttttt cacttcatac tgacgtccgt ttttagttaa tgggtcaata
      841 atcccataac gatgagtatc tgcttccgga acttcttgga cacctataac tgagtgccct
      901 gtttcttcat aaacgtcaat caactgtttc actgctggca cttcagattc aacaatatcg
      961 tcacctaata ataccgcaaa tggttcattg ccgataaatt gacgcgcaga actaatcgca
     1021 tgccctaaac ctttttgttc tttctgcctt acataaaaaa tattcgcaag ttctgttgaa
     1081 tactgaactt tttctagtaa ctcagattta cctttttctt ttaacaccat ttctaattct
     1141 ttttgactat caaaatgatc ttcaatcgcg cgtttgtggc gacctgtcac tataataata
     1201 tcttcaattc cagctcttgc agcttcttca acgatatatt gtattgtggg tttatctaag
     1261 ataggaagca tttcctttgg catcgcttta gttgctggta aaaatctagt ccctaaacca
     1321 gcagcgggaa tgattgcctt ttttattttt ttcaaagtta atgtgctcct tttcctaagt
     1381 attaaatcta tgtatcaacg tcattttaac actaattaga acgccttcat agtgtcatta
     1441 agtatgtaat tatttcttgg gaaatttgat ttaattttaa aaaacaggct tacttcatat
     1501 aatttatgaa ataaacctgt caattttaga ttgattatgc tttgtgattc tttttatttc
     1561 tgcgtaataa tgcaaatcct aaaatactaa acaatcctcc gaacagtata cctttgtttg
     1621 ttgattcttc tccacctgtt tcaggtagtt cagatttctt agattgtgct tttttagttg
     1681 gtgccactgc tttaaccttt tcattgattt caatgacagg tgttactacc ttaccttgtt
     1741 ccactggttt agaaggcttt ttaggttctt ctttggcagg tggtactggt ttaccaggtt
     1801 cagctggtac ctctggcgtt ggtggtgttg gtgtttccgg ctcacttggt acctctggtg
     1861 ttggcggtgt tggtgtttcc ggctcacttg gtacttctgg tgtcggtggt gttggtgttt
     1921 ccggctcact tggtacttct ggtgttggtg gtgttggcgg cgttgtatct tcttcaatcg
     1981 tttgttgacc ttcattatga ccacttactt gtggaagtgt atcttcttca tattcaacac
     2041 tattgtgtcc accgaattga taatttggtt tatctttgtt tgtatcttct tcaataattt
     2101 cagtgtgctt attgaatcca tgaatatgtg gcacgctgtc gaagtcgata tcaatgatat
     2161 taccaccatg ttcatattta ggcttgtctt tctctgtatc ttcttcgaat gactgatcac
     2221 ctttattttg accatgaatt tgaggtacac tatcgaaatc gatatctacg atattgccac
     2281 cttgttcata tttaggttta tcttcttctg tgtcttcctc gaatgactgg ttaccgctat
     2341 tttggccacc ttcataacct aattcactct taatatcaac gtggctattt tcttcgattt
     2401 cttcaatcac accataattc ccgtgaccat tttcagttcc taaaccagaa tgagaaatat
     2461 gatgattgtt ttcagtaatt tcctcgattg gtccttgtgc ttgaccatgc tcttcaggta
     2521 attcatctac tagttcaatc agattacttt cagtcgtata ttctttcgta tcttcaactg
     2581 ttgtatggtc gctcactgcg ccagttagaa taccttttgt agactcttcg tcaaattcaa
     2641 ctaagttaga ctcagttatt acttggccac cacctgggtt tgtatcctct tcatattcaa
     2701 caacatcagc gtgatgtttt gaattttcat gtgtagattc ttcaaaatcc acatgaatag
     2761 aatcttcttc agtttcaata ataccttctg catgaccttc tacaccttca acagctgtat
     2821 gatattcaaa atcaattggc ttagaatcgt tactttcttc gattgtacca gtcaattcat
     2881 gcttctccac tggcggctct gatttaatgt ctaattcaat tggttcactc ttctcaatga
     2941 taggatcatt tggcttatct ttaccgtcgc cttgagcgtt attagagtag aatgcaacgc
     3001 cattgtccca tgttaaactt actggataat aatagtaata accgtaatta gcatgatagc
     3061 catgcaaatt agttctgaat aataactcct tgtcattttc attatattta ccttcaaaac
     3121 ttacaacata acttttctta tttagtgcat ctaaagttaa tttatagcta ccgttttcac
     3181 ttagcgttaa tttatcactc atgtcattgg taacatcttt aaatttctct tgatcatttg
     3241 tgttagcata gacgctttct ggtaattcat cacttctcaa atactcataa actttcactg
     3301 ttggaacatt tcctgtatac aatccacctt tagcaaaaaa cccatttata gttattgagg
     3361 tcatatcgct ttttttaggg tttatataag ctaaatgatg tattttacta ttttctttat
     3421 ctaataaagt tatacgtcca tttacagtta ctccccagtt atctttaaca ccgtctagat
     3481 atttgatatc aaattctttt gaaatcttat tttcacctaa tttaacctca acagtttgct
     3541 ttccttgctt cgtaactgta gttggatcaa taaacaaatt taagtttaat tcagccatta
     3601 aattattttt gttatttata taatcagtaa acgtatatct aatttttctt tcatccatca
     3661 ctttgccaac agccaaaata ttatcatctt tactttttat atctggaact ttacgaagag
     3721 gcgagatacc atgagtttct acattattac ttaatgtgaa atcaaagtag tcccccggtt
     3781 taataccatc ctcgaatttc catttatatt tcaaggttac tctttctgca ttatgaggat
     3841 taacaacatt tgtctcttta ttgttatgcc ctactatttc actaccttct tctacttcca
     3901 ctttacttgt tacatctgta cctgtcgctt tagcttcttc cactacttct ttctctgtaa
     3961 ctgctgtaac atcagttgat cttttcattc ttggtttaat ttctgagaca ttacttggtt
     4021 gagctgtgtc aacttgagtt cctgtagttt ccttatcagc aactttttcc gatggcaaat
     4081 caactcgcga agtttctact tttggtgctt gcacagttgt tggtgcttct tctgttgtta
     4141 cttgtgttga ttgtgatggt tgctcagttg atgtcgcgct gtatgattgt gtttcatcta
     4201 ttgtattaac gttatttgta gttgtttgtg tttcgcttgc ttttctttca gtagctgaac
     4261 tcccactttc ctctactgta gtattgtttt gttccgatgc tgcagcttct ttttcttgtc
     4321 ccattccaac aacgatcatt gttcctaaga atactgaggc cgctcccaat ttgtgttttc
     4381 ttatgccgta tctaagattg cttttcacta taatattctc ccttaaatgt aaaattcatt
     4441 tattttttaa ctcaataaat gcaattctat attgttcggt ttttaaaagc aatgaaaaaa
     4501 agcgagttaa taaaaagtta agattgttgt taactttatg tataatgagt tttttattat
     4561 ttgaaactca catatatatt gcatacaaag ctcttgaata ccttgatata acaggcttgt
     4621 attttttata cttacttttt aaattaaatt aaaattcatc taatttaaaa caatatacta
     4681 aaacatacat aataatcgcc tgtacaatgc atcattaaca agtcactgaa acgcctttca
     4741 ttgtattaat aacgtcacta caatttttat atcgttcggt ttttgtttgg ttttaatgat
     4801 tgtttataca gaaacagccg tatttcaaga cgatatttta aatttaacta aatttgcatc
     4861 tagttaataa ttgcatttat ctaatttgtc ttattgattc aatctaattt gtacttacaa
     4921 actagtttta aattctaact ttatctctca gttcgttatc aatcatcaga cataaaccaa
     4981 tgaagcaatc agaaaacact ctaattttct attagaaatt tgatttaatc taaaaaaaca
     5041 ggtttacttc atataattta tgaaataaac ccgtcaattt ttgtttaatt atgctttgtt
     5101 attcttttta tttctgcgta ataatgctaa acctagaatg ctgaataatc cgccgaacaa
     5161 catacctttg tttgttgatt cttctccacc tgtttcaggt agttcagatt tcttagattg
     5221 tgctttttta gttggtgcca ctgctttaac cttttcattg atttcaataa caggtgttac
     5281 tactttacct tgttccactg gtttagaagg ctttttaggt tcttcttttg cgggtggtac
     5341 tggtttacca ggttcagctg gtacctctgg tgttggcggt gttggtgttt ctggctcact
     5401 cggcacttct ggtgtcggtg gtgttggtgt ttccggctca cttggtactt ccggagtcgg
     5461 tggtgttggt gtttccggct cacttggtac ttctggtgtc ggtggtgttg gcggcgttgt
     5521 atcttcttca atcgtttgct gaccttcatt ttgaccgctt acttttggaa gtgtatcttc
     5581 ttcaaaatca acactgttgt gtccaccgaa ttgataattt ggtttatctt tgtttgtatc
     5641 ttcttcaata atttcagtgt gcttattgaa tccatgaatt tgtggcacac tgtcgaagtc
     5701 gatatcaatg atattaccac cttgttcata cttaggtttg tctttctctg tatcttcttc
     5761 gaatgactgg ttaccattat tttgaccttg gatttgaggt acactgtcga aatcgatatc
     5821 tacgatattg ccaccttgtt catatttagg tttgtcttct tctgtgtctt cctcgaatga
     5881 ctggttaccg ctattttggc caccttcata acctaattca ctcttaatat caacatgact
     5941 attttcttcg atttcttcaa tcacgccata attaccgtga ccattttcag ttcctaaacc
     6001 agaatgagaa atatgatgat tgttttcagt gatttcctcg attggacctt gagcttgacc
     6061 atgttcttct ggtagttcat ccactagttc aatcagatta ctttcagtcg tatattcttt
     6121 cgtatcttca attgttgtat gatcgctcac tgcgccagtt acaatacctt ttgtagactc
     6181 ttcgtcaaat tcaactaagt tagactcagt agtaacctga ccaccacctg gatttgtatc
     6241 ctcttcatat tcaacaacat cagcgtgatg ttttgaattt tcatgtgtcg attcttcaaa
     6301 gtcaattgga tttgattcct cagaggactc agtgtatcct ccaacgtgac ccgcttcact
     6361 atccacagca gtatggtaat cgatatcaat agctgatgaa tccgtttctt ctattgtttc
     6421 aatataccca tcaacataac caccctcacc atctatagct gtgtggtaat caatgtcaag
     6481 cggtgtattg tcttgatttt cttctgtttc aataatttgc ttggcatcgt actgcccgct
     6541 catagttcct tttgcagtat cttctttata ttcaaaatca ttattttgaa taatttgtcc
     6601 atttttacca ttgccgtcag ctttattgct atataaaact aaaccattat cccaagttaa
     6661 acgatatccc ccataaacat agtaagattt atatgctcgt tctggatacc catataattc
     6721 agttctaaaa ttaacctgat ctgacccttg caaatattca cctgtataat gaatgacata
     6781 cgttttatcc aacttatcta aattcaatga gtaactacca ttgtcttgca cactcaattt
     6841 tccattcatt tcctttgtta catctttgaa tttgttagta tctgatgtat ttgcataaac
     6901 actttgtggc aattcatctt ttttccctag atattcatat actttaacag taggttgtcc
     6961 accagctaaa ttactacctt cagtcaacgt ccctgttact gatacagtgt ttgactggtt
     7021 tccattcatt ggcttaatat aagctatatg tgtaaattta ttagattctt tattaaatgt
     7081 ttcaattgat ccatttacat ttgtataact attgctaaca cctggattat aaacaactgg
     7141 tattgttttt tctgtttctt caccatttaa tttagaagta atcttttgtt ctccattgct
     7201 ttgtacagtt ttagggtcaa taaataagtt gatttctaaa ttagctgtta cctctacctt
     7261 gtgttcaatt tcgttagtaa atgtatatct tatgttacca ttccctaaga tctcacctgt
     7321 agccattaca actgagccat ttttaatctc tggtaccttt ctagctgttg aaaccccata
     7381 agtatttaca ttatttgata atgtaaaatc aaaataatct cctcttttta atccatctgc
     7441 gaatttcaat ttgtatttca atacgacacg ttgaccagca tgtggctcta ctttatttcc
     7501 ttgaggtgcc tcaatagaac cactttctac tgtaacttta cttgtcacat ctgtacccgt
     7561 ttccactttc tcgtcactag cttccttagc ttcaactacg tctgctgatc ttgtcacacg
     7621 tggtttactt tctgatgccg ttcttggctg tgccacttca acttgtgttt ctgcgacttg
     7681 attttgtgtg gcctttttag gtgttaaatc tacttgtctt tgatctccgc tattgtcttg
     7741 agattgtgtt gtttccttaa cttgaggttt cgcttcttcc ttaactacct cttctttaac
     7801 tgtttctaaa tttgctggtt gtgcagtttg tggtgcttgt actgcttttg gtgcttcttc
     7861 agttgttact tgtgttgcgt ttgacggttg ttctgttgct gttgcgctgt atgattgtgt
     7921 ttcatctata gtattaacgt tagttgtagt tgtttgtgtt tcgtttactt tattttcagt
     7981 agctgaattc ccattttctt ctactgtagt tgtcttttgt tctgatgctg cagcttcttt
     8041 atcttgtccc atcccaacaa cgatcattgt tcctaagaat actgatgctg ctcccaattt
     8101 atgttttcta atgccgtacc taagattgtt tttcactgta atatctccct ttaaatgcaa
     8161 aattcattaa tttttttaaa cttaataaat gcaagtctat attgttcggt ttttaaaagc
     8221 aatacaaaaa agcgagttaa tgaaaagtta agattgtcat taattttatg ttaattgata
     8281 attttattat ttgaaatata cctataaatt gtattcaagt catcataaac ccttgtcaca
     8341 caaggcttgt attttttata cttatttttc aaattaaatt catcattatc taatttaaaa
     8401 caatatacta agcgtttcat aattatcgcc tgtacaatac gcacaaaaac atgtcttgaa
     8461 acgcctttca ttacactaaa atccccaata tactttttat atcgttcgga ttctgactat
     8521 ttcagacgat tttctgcata aaaataaacg tgtttcaagg caatatattg caattacctt
     8581 aaaacacgtt tacttaatat ttagttaaac aaataagctg atgaatagaa tgaagatgat
     8641 acctgaaacg gaaataatcg tttctaataa tgaccatgtt aagaatgttt cttttacagt
     8701 taaaccaaaa tattctttaa acatccaaaa tcctgcgtca tttacatgag acaaaatcac
     8761 actacctgca cctatcgcaa gtacaactaa tgcaacattt acatctgatg attgtaataa
     8821 tggtaagaca atacctgtag ttgaaatcgc agctactgta gccgaaccta atgcgatacg
     8881 tagcacagct gcaacaatcc atgctagtaa aattggagac atctctgtac cttcaaacat
     8941 tttagcaatt gtatttccga caccaccgtc aattaatact tgtttaaatg taccgccacc
     9001 gccaataatc aataacatca ttccgattgg ataaatcgca ttcgtcactg attccataat
     9061 atgattcatc ttacgttttc tcattaatcc catcgtaacg attgcaaata atactgctat
     9121 tagcatggct gtccctgctg ttcctatcat ataaatgata gattcaaata gatttgtagg
     9181 tttgtcgtgc ccagttacaa gttgcgttat cgtagacact aacattaata tgactggtaa
     9241 tgttgcagtt aataaactca taccaaatcc tggcatctct tgatccgtaa attctttttg
     9301 tgcacctaac gctgaaatat cgccttctcg tgtatacgca gacggaatca ttttttgtgc
     9361 aactttgtta aatataggtc ctgcaatgag tgtaactgga atggcaataa tcataccgta
     9421 cagtaataca tctccaacat ttgcctttaa ttcttttgcg atgactaccg gtcctggatg
     9481 tggtggtaaa aagccatgtg tcacagataa agctgttacc ataggtagtc ctagttttaa
     9541 cactgaaaca tttgcgcgtt ttgctactgt aaatactaat ggaatcagta agactaaacc
     9601 tacttcaaag aacaatgcaa taccgacgat aaatgctgca acaagcattg cccattgtac
     9661 atgtttttga ccaaattttt gaatcaacgt gtctgcaatt cgagttgcac caccaccatc
     9721 agcaagtaat ttcccaagta tggcacctaa accgaatatt agtgcaatgt ggccgagcgt
     9781 actgcccatc cctttctcaa tcgtctccat aattttagtc aatggtatac ctagcattaa
     9841 cgctgtaatc atcgatgtga taattaatga aataaatgta tttaatttaa acccaataat
     9901 taatactaat aaaataacga tacctaaaac aacactgatt aacggccata tttcgttaaa
     9961 catgacattc ccctctttct cttttcaata gaatgtaaca ccgtcgtcgc gcacgtattc
    10021 cacataatat atagtagtca tggcacaaca actttatcta agatgcttaa gtgacgtatt
    10081 tattgtgttt tattttcagc catatgttgg cgttgaaaat ctgcaatttg ttcataattc
    10141 tctgttaaag aacgacttaa attgataaaa atggatacga gctcttggta aacagcgaca
    10201 ttttcttcaa acggcatatg attatttgta gcaccgacca tcgatgaaac gattgaaaaa
    10261 tcttcaatgt cacctacagc tttaagtcca agcacgcagg cacctaagca tgaactttca
    10321 tagctttcag gaaccactaa ctctgtgtca aatatatctg acatcatttg acgccatact
    10381 tcacttttcg caaaaccacc tgttgctttt atcatcttag gcgtttcatt cattacttca
    10441 atgagtgcaa ggtagacggt atacaaattg taaagaacac cttctaatgc agcgcgaatc
    10501 atatgttctt ttttatgaga taaagttaaa ccgaagaatg aacctcttgc atttgcgttc
    10561 caaagcggtg cacgttctcc agctaaatag ggatggaata ttaaaccatc tgcacctggt
    10621 ttaacacgct ttgcaatttg agttaagaca tcataaggat caacaccgag acgtttcgca
    10681 gtttcgactt cactcgctag caactcgtcg cgcaaccatc tcaatacgac accaccatta
    10741 tttacaggac ctccgatgac gtagtggtcc tctgttaaga cataacaaaa tattctacct
    10801 ttgtaatcag tacgcggttt atctatcaca gtacgaatcg ccccagatgt accgattgtg
    10861 acagcaactt ctcctttacc aacgctattg acacccaaat tagaaaggac cccatcactc
    10921 gcaccaataa caaacggtgt atcttcatta agccccatta atgttgcata acgttctttc
    10981 atgcctttca ttacgtacgt tgttggcact aattccggca acatttcctt ggaaatacca
    11041 agcaattcta atgccccaac atcccaatct aatgtttcta aattaaacat ccctgttgcg
    11101 gaagccattg aataatcaat gatatatgta tcaaataaat gatagaaaat gtatgtttta
    11161 atatctgcaa acttagcagt acgttgaaat acatcttgcc attcatgttt catccaaaaa
    11221 attttcacta aaggcgacat aggatgaata ggcgtacctg ttcgctgata aatcgcattg
    11281 ccatcatgca cttcatttat tactgttgca tattttgcag cgcggttatc tgcccaagta
    11341 atattatttg ttaatctttg atgtttctga tccatcgcaa tcaagctatg catttgcgca
    11401 ctaaatgaca caaatttaat atcatcttta ttaactttgg attctctcat aacatattta
    11461 atagtcatta ataccgcatc aaataattca tctgggtttt cttctgagac atcaacgttt
    11521 ggtgtgtgta aatcatagcc gatttgatgt ttcatgatga atgttccatt gtcatcatat
    11581 aagactgact tggtactcgt cgttccaatg tcgacaccaa tcatatattt catgacaaat
    11641 ccttctttct ttcattttaa ttcaaccaaa atccttcaat atctttacca acatcgtcga
    11701 aatttaagtg aaacgcttct ttcaaaattt gactgtcgta ttgttccact gcatcaataa
    11761 acacttgatg attatgatgt atgcgttcaa aatcttgcgg gttctgttgc atacgttgtc
    11821 gcatggatgt taaaacgagt gccatcatta ctggttttaa atgactccaa aatgagttta
    11881 aatattgatg attagatgct ttgattaatg tttcatgaaa ttcaaagtca tgcttcgtaa
    11941 atgattctgc atcctcaaat tttactgcca ctttcatcat ttcaagttgt ttcttcattt
    12001 cttttacgat aggtagtcgc tcttgatttt taactcttga aaatgcaaaa gactctagca
    12061 tcagtcgcaa atcgtacatt tctttctttt cttgttcccc aaacggcaac acatgtgcac
    12121 ccattctttc taattggatg agttgatttt gttgcaataa tttaaatgca tctcgaattg
    12181 gcgaacgact cacattaaat tgctttgcca tttgattttc agtgagtaac gtaccttcag
    12241 ctatgtgacc attcacaata cctaagcgta attctgccgc gataccttct ccagttgtca
    12301 taccttccaa ccatttctct ggatatccat acatcatcaa agccactcct tcattacacg
    12361 acatacttgt atacaagtat gttaatatag ttcttaatcg tttgcaagcg ctttctttac
    12421 gcgtactaaa atagcgacca ccccttttcg atgtaagttt aaagggaatg gtcactatca
    12481 cacgaataat ttaattgtta tgttgtatgc gggatatttc taattgttct gtactcatat
    12541 gcgctttagg tacttcaatg caataatgcg tttcatgaca gttcggacat tcgaatcgac
    12601 gtgttgtcgc tgtatgtttc gctttgataa ctgcccacaa agatggtgag aatatatgct
    12661 ggcagttagg acataaatag gcaacctttt gttggtaata aaaagtaaca ccaatgccgt
    12721 atccaatcat aaacggcaac gcaattagaa acggccattt atttttcatc aaaattgcac
    12781 ttataatgct agaatattga attattccta taatacccgc actaatccaa atgttacgac
    12841 gaatactttt catttcagct gatttactca tgacatgctc tatgtctttt aaatgtgtga
    12901 ttggagacgt cgacgcttta tttacgtaat attgaacatt tttaattttg tttaataccg
    12961 cttgttgctg tttgacttgt tgattaattt cttgttgttt catagttagt aaagtattga
    13021 gtgtcttcaa agtaccttca ccttttagca acatatctat atcgcttaac gcacaaccta
    13081 aatctttaag caataagatt aactctaatg tttgtcgctg ttgttctgta tacacacgac
    13141 gctttccttc tgtaaatcct tgtggtttca aaataccttt gcgatcataa tattgaatcg
    13201 ttcgcgttgt cacattgcat aatttcgcga gttctccagt cgaatagtta gacatagatt
    13261 ccacctccta caatcaccat agttgatgac ccgacgtcac gagcaagtac tttttctaca
    13321 ttttaaagaa atttattata ctaggcgtct tatttttgtg atttcgtacc atgttgattt
    13381 acaaaatcac tcaaattaag caacactact actaaacgtc tactctgtta tttcagaatg
    13441 aatttgttgt aatttatctt caacttcagt aatctctgtc gcacattctt tcagtaaatc
    13501 tcgatacttt tccgtctctg cattgttttt ataacgtatt ttatgttcta aacttgccca
    13561 catatccata cctatcgttc taatttgaat ttcaacaggc aatacctcaa cgcgttctgc
    13621 taaaaagact ggaatggata caacgatatg taaactgcgg taaccatttt ctttagggtg
    13681 ctgaatataa tctttacgtt ttatcaattg tacgtcttct tgtttaagca acatctcttc
    13741 aatcaaataa atatcatcta agtaattaca tactacgcga attccggcaa tatccagtat
    13801 atgttctttg gcagtttctg cgctaatctg taatccttta cgattaagct tttctattaa
    13861 actgcgcatt tctttcacac gtcgctccat atgatgtata gggttgtgtt tataaatgtg
    13921 attgaaatta tcgtctaaaa tactcagttt agtgcttatt tcctttagtg ctgacgaata
    13981 aatatgatct aactctacga aacctaataa cgtatcaaat gcttcatcac cattttcaaa
    14041 tttacttaaa ctatttttaa aatcatgtcg caaatcctct aaatatagtg atggttttcg
    14101 atctacatac atttttatac taacctccga tatataatca tctttattgt acctaacatt
    14161 ttattaagat aatactaata cactatcgaa ctttgggctg atactgaaac agcacaaaga
    14221 aactcaaaca attcgaatta tgtatcaaaa ccttcaatta taggaagtaa ttttaaaatg
    14281 atttaacgca aaaaaacacc tgttaccgtt atataggtac aagtgtttaa ttgatagaga
    14341 tgttatacgt ctttaaatga ttccacaact tttggatgtg gaccatccat aagcggttct
    14401 ctttgtcgaa cgccaccact ttggttgcca attgattcgc tatcaaagta cgatttatct
    14461 tgatttgatt gttcttgaat atgttcttca ttatcagttg ttgcatattc actatccacc
    14521 tctgtttttt ccattgttgc tgtatggaat tgtacgaagt tctcttcttc taatgctttg
    14581 atttcttctt tcgataacgc tcgataccaa tctttcgctt ttttcgccgc aataggaaca
    14641 acatcttttt caagatatcc ttcttttaac attgcattcg caatttctat cgctttttgc
    14701 cgtttaatta cttcaaaatc tttccatttt tcggggtaac ctttcattgt aaagggcatt
    14761 tccttaacct ccaatatgtt ataattcatg ttatatacca ccataattat aaaatgaaac
    14821 atattaaaca caatttttta gactcccgtc ataataactt cagacaaacg ttagtctgac
    14881 ctgataaata ttttatttta aacgttcttg tctctctcac aaaaactatt gtgttgaata
    14941 ttcatcattg ctgattgaat ataattatac tgtggtaaat ctggtaatat ctttatttct
    15001 aattctgtat ttaattctaa atgcttagcg atgttttcaa atgttgctaa atactcgccc
    15061 attaattgtt catttattgt aagtctatct tcattagcca tggctctatt taacataaag
    15121 ctaatttctt ctaatgcgaa taagctagga taataatttt gaatcaatgt cttatcacta
    15181 aataattcac cattagctgc attataaact tgcgtcatgt tatttaattt cacagatagg
    15241 ttcatagccg tgtttttctg atacacatca tctttatatt ggttttcaga aaacaaataa
    15301 tggaagagcg ttgcttcttt acgaacaact tcagccatta cattaggaag caatgcggat
    15361 gcggtacgtt gtccaaggac aaataaacct atgattgcaa tcacaatacc cattgcaacg
    15421 tcaataactc ttggaaacgc aatgttaatt gttaaattct gtgatgctaa tccattcatt
    15481 aaaataactt gtattgtaat aaaaactact gcaatcgcat aatttgctcc caccaatgct
    15541 tcagtaaaca atgctgcaat gcccattaaa attactgcaa caggtgttgg tattgaaaac
    15601 aacaatatga ctgaaagtac taacacacct aaaatagtac ctaaacctcg tgccatacct
    15661 ctctcgattg catgtatagt tgatgttcct agtaatattg tatgtgcaga taacggtatc
    15721 cagtatgctt tttcaaaatc aaacattaac gcaataaata tcgctatcat cataatcgct
    15781 gtatatctca atgtatttct aaaaacaata gagtctaatg ttaaattttg ataaatgcgt
    15841 ttactatata aaggttttcg catgtctgct tcatacgcaa tacgcgcttc atttgcatgc
    15901 accatttcat caattttcaa tatgtggttg aataaatttt gaaattcctc tgttactgtc
    15961 acttcttttc gccaatatct tacattttcc tcactattat ctagttgtgc aatgatatga
    16021 tccatcattt caattaactc atctggcaat ggtcgaattt gtttagcgtt caactctaac
    16081 agttcagaat aaatcccttg ggcagatgtg tgtaataata ataatttttg gaaacgtcta
    16141 cttaatttat cgttacttga agtagaagtg attaataatt tatcagatgc tttaaaatta
    16201 tccaccgctg tttttgctac ttgtaaaaat gcagatttat cattataagt gtgtaacaac
    16261 ttagatatga gtttaaaatc attttgaatt gcttgttctt cagctttgtt tttagaaaat
    16321 acgatcgtga ttaacaccat catagtggca agtataccgc ctactaaaat cgcaaagcct
    16381 ctatataatg cttcttcggg agctataggt aagttaatgg gtagactgaa tgtcacaatg
    16441 aagaatgtcg atgacggtcc agctattttt aaggcagtaa atatataaaa tggtataacc
    16501 gtaacaatta ataatgtcat tccaaaaacg agtggcgttt tggctgttag cgtaccaagc
    16561 atcatacata ttgcaaacgc taaattacaa attattacag ttcgcagctt agatcgcgac
    16621 ggacctttaa aaacataaat atgggctagt gttccggttg caactaataa tccaaattgg
    16681 aaattaccac ataagtaacc gattattgcg ggaataatca ttaacagtcc ctgtcttaca
    16741 cctttataaa agtctaagtt aagtcgattg atttttatga gtgatgtcaa aaagatgtca
    16801 tttcgacttc tcctttcctt gtcaaaatat ttccataatc tttttattag catagttaaa
    16861 atgaatttgt tgctataaat tttaattacg caacatatgt cattataaca ccttatgctc
    16921 aattatctaa atttaaaaac ttttaaagtc caattaaaat taatttctaa tgttatttaa
    16981 catcgttgaa cctttggtcg cccacctttg cgctagttaa aatttatttg tgacatgttg
    17041 aaattatttt agcgaattat acatttaggg ttagaaaaac attcacatag acttagtgtc
    17101 tatttacttc atattattcc tagggttcaa gatccaaact atagtaaatt taagaaagtt
    17161 tataaaacat atttgcttca taagcttgaa tagttcctat attcgttatt taaaatgaca
    17221 ttcgatgtca gttcattttt taaaatatcg aaagatgctt acgtataata tatatagtga
    17281 cgtatttaca aataatggca gtaagcagta caaaatgatt acacaaaaat ttccttctac
    17341 tcgataaatt aagaagaata aactaattaa aaaaatactt ataattagac ctataagagg
    17401 caaacttcta atatatttct ctaagttttc cttcatattt ataacctcct aaaatttata
    17461 tgtactttta taagcgttac ctgactaatg ttttaaaact ttatttcttt acatacatca
    17521 ttttaataac ttctctttca tcttaaacca tatctgtttt aaaaagtttc aatttcaacg
    17581 taaaaaaagc aataagcccc aacaatgtga aagcttactg cttgtttaaa ttatttttct
    17641 attgctttat catcactaac aattaaaggt tgatctggtt tcacatagaa ccacataatc
    17701 acagcgatta ctgctggaac gattaacaat tggaatgtca ttgtccaacc caaatgttct
    17761 acgaatagac ctgctaatag cggactgatt aatgcaccta tattacccca taagttcatc
    17821 caccctgata ctgtaccaga gaagttacgt cctaagtcag ttgctgcagc ccaactcata
    17881 cccattgaaa taccgatacc accaagacct agtgataacc agaaaatact tacatataaa
    17941 tttcctgtac gtacagcaaa gataattgaa actgcaaaca caataaatcc tgcgattgca
    18001 attacacctc tagctacgaa ttttgaacga cctaatccta atacacggtc agaaattgca
    18061 cctgctgata agattaagaa gaacattaat aaccaaggta atgaactaat gctcatttct
    18121 ttaaagttaa cgtggaatac ttctgttaaa tacgtcggta accaaattaa gaataatgta
    18181 atgataaatt gtacaacaaa gtattgaatt gcaattgcat agaagctaaa acgcttaaag
    18241 aaatcattcc atggtggtga tgacttttca gtagctacga tatcacgatt ttccataatg
    18301 aaacgtttct ccgcttcatt aaccattcta tgttgctcag gtaagtcttt ggcaataatc
    18361 gcccataata cagccattaa aatacctact gcaccaaaaa tgtaaaatac tgcttgccag
    18421 ttaaatgcgt taacaatagc aattgtaact attggtgcta atacaggtcc gaaatatgat
    18481 cctgctaata atgcacttga tgctctacct ttttcatttt tagagaacca aaatgagtta
    18541 aacacagcat tagaagggta cattggcgcc tcacctacac caaataagaa tctcactaaa
    18601 taaattaaac cgtggttctt aatcataccc gttaagattg taaatgcact ccaccaaact
    18661 aatgcaattg taatcatctt acgtggaccg aatttttcag ccaacatccc cgatggtact
    18721 tgcattaatg cataacctag agagaagaat gatgccaata aaccaaattg tggctttgtc
    18781 atccctaaat catccatcat ttgcttagcg atatatgaaa tgtttgctct atccatatac
    18841 gcaataaccc caataaagaa gaacgcaagc gcgaacatcc accttacgtt agttcgtttt
    18901 tccttcataa ctattcctac ttccctaatt aattttttaa aacttaccct gaaacgttaa
    18961 aattttcgga catctggcat gtccacccct actttgtcac aaaattgtac caaagttatt
    19021 ttttataata ttatcagaca tggaaagcgt ttacaataga atctataaaa attttattaa
    19081 attccgctta acttttgcta ttaaaacgat ataaaggaac ttttagttac atagtagcct
    19141 atcatttgtt aattaaaaat actgcaatgc tagtgtttta aaacgtatat tgcaggcttt
    19201 cttacatatt tgacattcat tttaaattgc ataaaactac attgctcatt cattgtgcag
    19261 cgcctgttat ttagatgatc atttgttgac ttttcgtact tatagcaagc aattttttga
    19321 tttattgctt ataatacatt ttaagacaaa tgcttgtttc aacatcgcat acgacatcat
    19381 tcattattca tttgaattta tccagtttct atttgtctgc aattgctgaa aattaaagga
    19441 gcttattttt aataatggaa caaattatca ctgaatttat tagtcgtttt gggtatgcag
    19501 ccatttttat attaatttta ttagaaaatg ttttacctat cgtaccatcg gaaattattc
    19561 tgacatttgc tggccttatg tctgttaaat cacatttatc aattttaacc ttatttatta
    19621 ttgcaaccat cgcatcgttt atagggctgt taattttata ttatatctgt cgtttgattt
    19681 cagaagaacg tctatatcgt tttattgatc gacacggtaa gtggattaaa ttgaaaagta
    19741 aggatttaaa gagagcaaat gattggttta aaaagtatgg cgtatgggct gtatttatct
    19801 gtcgtttcat acctgtatta cgtgtattga ttaccattcc agccggtgta aaccgcatga
    19861 atgttgtgac atttaccgtt atttcattaa taggtacaac aatttggaat ttcggtttaa
    19921 ttttactagg acgcactttg agcgatagct ttggtatgtt gatgactggt cttcatacat
    19981 attcacgtat tatgtatgtt atcatcatta tcgcagtcat ttactttgct atacgttaca
    20041 tcggcaaacg taaaagagta aaataatatt gttgttagta taaaggcatg aattttaaat
    20101 ttctatacac aaaaagcagt aaaatcattc catctattga aatgattcac tgctttttta
    20161 agtttatttg gcaaacttta gctgaaagtc acctatcttt atataaagaa atattattat
    20221 taacatgata gttacagttg tgaaataaaa tggtaccaat gagtgagaaa tgataccaat
    20281 taataatgcg ccgacagtca ttccaatata tctcacaaag ttaaatacac ctaacacttt
    20341 tccttttata tgttcaaacc ttttagaaat tatagtagac agcaaagctg gcacaatacc
    20401 aacacaagta cctaatataa atataattac tgataatata attacatttg attcgtttaa
    20461 ccatccaaac aataatgtaa atatagcaaa tccagttata gtaacacgaa gtatcattat
    20521 ttcattatat ttttttgaca atcgtttata aaataaactt cctaatataa cactaacagt
    20581 aataggtaaa aacaaaactc ctgatattcc aacgcctata tcataggtat tatttaataa
    20641 tgtcggtaaa taaactaata ttgaaaagta cgtcaaaaat attaaaaatc ccaatgtcac
    20701 taaagtaata aacactttat cgatcaaata tttttcttca attttttcag ttaattttac
    20761 aatccctttt tcaacatttg gaatatcaat aaaaaagata atcagaaata atacgataga
    20821 tataacaagc aaaaaactaa aaataccaat ataatcccat cttgcaccta aagtactccc
    20881 taggattggt gccaaagctg gcgcacatga taaaaatatt tgatagttcg ccatagcttg
    20941 agctctacca ttatctgtac ttagtttggc taataaagtt aaagtcacga gaggaataat
    21001 tccgcaacca attgcttgaa ataaccttga tatagcaaat aatataaagt tatgtgtcat
    21061 tgcacaaata aagctagata tgattactat tcccaatccc gttaaaagta cttttttcga
    21121 atcacgagaa tctatacttc taccaagtac aatttgcata actgcaacga taaatataaa
    21181 accgccaact gtcgcattta tccaaaatag tggtacttga aaatcgtcat atagtctcgg
    21241 aataataggc gtgtatatgt tttgaatcaa tgatgcgaaa aatgctaaaa atcctagaat
    21301 atataatctg atattactat tagtcattta aaccatcttc ttcttttttt aattcttcta
    21361 tactacggtt taaaaactct acaataactg ccatttcatc attatcaaag actttaagta
    21421 cttcttcata tttttttacc gctttttcat gtaattcatc atgtatataa gataattttt
    21481 ttccttcttg tgttaatgaa taattaactt ctcttttgtt aaattcattg tgcgattcaa
    21541 ctactaagcc tttcgctaaa agttttttta tcgatttagt aattgctggt tttgatacat
    21601 ttaacatttc agacaaaaat ttattattca ctttatcatt agttaaccgg ttaactatat
    21661 tattgttgtc actcccattt ttgtcaaata ttgttgtaat taacatatat ttacttagtt
    21721 atgcaccatt tattccgcaa acccacctca caaatccatc tataatacaa actatcattt
    21781 taaataagca gaattttccc tgtcttccac acaaactgtt ttcgtcactg taatatgcct
    21841 tctattcaaa aaagtcactc ataacaaatt gcgcatttta ataaatgtag caatgccatt
    21901 tgcatgctgc aaaaatactc atattaatat ttatatttta tattatttaa gttttttaaa
    21961 tccatatttt tataacaatt gctatgtgat aaaattaatt ttatatataa aatcttaaga
    22021 ttcagattat ttaatagcaa aggagatagt gatatggatg ttttaacaat agaacattta
    22081 acaaagaaga taggcaacaa aacgattctc gaagatgtat catttaagct gaaacgcgga
    22141 caaatagttg gtcttgttgg agcgaatggt gcaggtaaaa caactttaat gaaagttata
    22201 ttaggttact ctagtttcca aagcgggaat tttaatgtta ttaacagcaa ggacagcaaa
    22261 agcaatatcg gtgcattgat tgaaaatcca ggaatatatc cttttatgtc tggatatgaa
    22321 aacttgaagt tattgaacga atcaaaaaac actcaagata tcgataaaat tgtctcacaa
    22381 cttcatatgg atgaatacat tcataaaaaa gctaaaacgt attctcttgg tatgaaacaa
    22441 aaattaggaa ttgctatagc atttttaaat aaacctcaat tcattatctt agatgaacca
    22501 atgaacggct tagatccaaa agctgtgcga gatgtacgtg aattgattgt acaaaaagcg
    22561 caagaaggtg tcactttctt aatttcgagt catattttaa gtgagttagt taaaatcaca
    22621 aactctatcc ttattattaa caaaggtaaa attgttacag aaacatcgga agaagaactt
    22681 aaacaattta aagataatga tttagaaaat gtattactag aaatcataga aagggaggat
    22741 caagcataaa atgggaactt taattaaaca agaatgtttc aaattattta aaaagaaatc
    22801 aacttttatc gcacctattg tctttattct actaatggtt gctcaaggtt atatcgctac
    22861 aaaatacaat gaaattttta cgccacagga atcttttaca tctgcttata atggtttttc
    22921 atggtttgca tttttattaa ttattcaagc aagtacaatc atttcaatgg aatttcatta
    22981 cggtacgatt aaaaatttac tctatcgtga atattcaaga acaactatga ttgttagcaa
    23041 aatcatcaca ttatttatta tttctttaat ttattttgtt attacaatta ttgcttcaat
    23101 tgttattggg tctttattct ttaatgattt aaatatattt gaaagtagcg gtaatcaatt
    23161 atctttattg aatcaattat tattagttag tttaggcaca tttgttggcg tttggttagt
    23221 tttaagctta acgttgctat tatcatctgc aacaaattca acgggtgtag ccattgctgt
    23281 aggtattgtt ttttattttg caagttctat tttagcagtt attcaaacgg cacttttaga
    23341 aaaaatagac tggctaaagt ggaatcctat taatatgatg aatattatgc ttcaaacagt
    23401 tgaaaaaggc tttagtaagt cgacaaaatt agaacttcat gaattgttta ttggtaatat
    23461 tgcttatatt tctattttct taatacttgt agtatttatt ttcaagaaga aaaatattta
    23521 gtaacttaaa gtattagatg aataaataca cacagattcc atcgtaattc aaaatcattt
    23581 tcaaatccct tcaccataat ggtgcgggga tttttgatat gtcagcatac cactcattct
    23641 atcttttata tattccagaa tccccccact tgtaatgtac aaaatatgct cacttatacg
    23701 ataatcgtat ctctgccaag ctatttcaac tctgcttcaa caactttatc acttcacatt
    23761 tatgcgggta cacttcaacg ctactaatat gaatgataca accatagatt ctcaacacta
    23821 aaattcacaa tatgtttact ctatttttat caattcaagc atacttattg aaaaatgtta
    23881 acgttttctt gataatcatt gtaagcgtat taattttaca aaccaatgat tgaaatatac
    23941 tacaggagtg acacacaatg actcaaatta ctgaaagaga attaaaaaag aaatatttgg
    24001 atttattatc tcaacatttc gatactccag aaaagcttgc gactgaaatt attaatttag
    24061 aatctattct agaattgcct aaaggtacgg agcatttcgt cagcgattta catggtgaat
    24121 atgaagcttt ccaacacgta ttacgcaacg gttctgggaa cgtgcgagcg aaaatcaatg
    24181 atattttcaa agacaagtta tcaacgaaag aacttaacga tttgactgcc cttgtttact
    24241 atccagaaga caaattgcag cttattaaat gcgattttca aaattacgga caattaaatg
    24301 tttggtatat tacgacgatt gaacatctca ttcagctaat taaatattgt tcttcaaaat
    24361 atacgcgttc aaaacttcga cgtgccttgc cggagcaata cgttttcatc gtagaagagt
    24421 tattatataa aaacaacgaa ttcaaaaata aaaaatctta ctacgaaaca cttgtaaatc
    24481 aagtgattga gcttaagcaa gcggatgatt taattatagg gcttgcgtat tctgtacaac
    24541 gcttagtcgt cgatcattta cacgttgtcg gcgatattta tgatcgtggc ccgcaaccag
    24601 ataaaatcat ggacacgctg attaattatc attctctgga tattcaatgg ggtaatcatg
    24661 atgtgctatg ggttggtgct tatgcagggt ctaaagtatg tttagctaat ttactacgta
    24721 tttgtgcacg ttatgacaat ctagatatcg ttgaagatgc ttacggtatt aatttaagac
    24781 ctttgctaac attagccgaa aaatactatg atgcagataa tcctgctttt aaacctaaaa
    24841 aaagacctga taaacatgaa cgtttaacac aacgcgaaga aagtcagatt actaaaattc
    24901 atcaagctat tgcgatgatt caattcaaac tggaaatacc ggttattaag cgccgtccaa
    24961 actttgaaat ggacgaacga cttgtacttg aaaaagttaa ttacgatact aatgaaataa
    25021 cagtatacgg aaaaacatat ccattaaaag atacatgctt ccaaactgtt aaccgtgata
    25081 acccagcaga attactacct gaagaagaag aagtcatgaa taaactatta ttgtcattcc
    25141 agcaatctga aaaattacgt cgtcatatgt ctttcttgat gcgtaaaggc tcactttact
    25201 taccttataa tggcaattta ctcattcatg gttgtattcc agttgatgaa aatggtgaga
    25261 tggaatcatt cgaaattgat ggtcagacat acagtggcca agagttatta gatgtgtttg
    25321 aatatcatgt ccgtaaatca tttgatgaaa aagaaaatac tgatgactta tccactgatt
    25381 tagtttggta tttatggact gggaaatatt cttcactatt tggtaaacgt gcgatgacta
    25441 cgtttgagcg atattttatt gcagataaag cttctcataa agaagaaaaa aacccgtact
    25501 atcatctacg tgaagatgtg aatatggttc gtaaaatgct cagtgatttt ggattaaatc
    25561 cagatgaagg acgcattatt aatggtcaca caccagtgaa agaaattaat ggcgaagatc
    25621 ctatcaaggc tgatggaaaa atgcttgtca ttgatggcgg cttttcaaaa gcttatcagt
    25681 caacaactgg cattgcaggt tatacattgt tgtataattc attcggaatg caactcgttg
    25741 cacatcaaca atttaacgca aaagaaaaaa ttctttccga aggtatcgac gaactgtcaa
    25801 ttaaacggat tgttgataaa gaattgcaac gtaaaaaaat ccgtaataca aataaaggta
    25861 aagagcttca agctcaaata gatattttga aaatgttaat gcatgatcgt tacttagact
    25921 aaagacgaca tttggtgcat gcatcgtgca cttacttaat ggtactttgt ttacgcattg
    25981 gctacgcaaa cgcgatggta aatagtcgac ctaactacac cgaaaaatcc cctcactatt
    26041 gcgagtagtg aggggattgg tgtatctatg ctagttcctg ttaactgtat tataacaact
    26101 tcacagcaaa aaaatgcaaa atcaactaat aaattaatga aatgaccgac gccctcgctt
    26161 ctactccaat ttaacaaaat actatattag tactatattt ttcattaaca tgtatgttac
    26221 attttctata ttacttaaaa ttacgaaggg acatttttaa atcatgcgta tcttaaaaga
    26281 gtccattatt gtggcatttg cctttgttgg tgttgtcgtt ggtgccggct ttgctactgg
    26341 tcaagaaatt ttccagtttt tcacaagtca tggcgtgtat agcatttcag gcattattgt
    26401 gacaggacta ttgattactt taggtggaat gattgtcatg catacaggtc atcatctaaa
    26461 gtctagaaat cattctgatt caattaacta tttcttatat ccctctattg caagaggttt
    26521 tgatattatt ttgacaatgt ttatgttgtc tttagctatt attatgactg caggtggcgc
    26581 ttcaaccatt catcaaagtt tcaacttacc gtattggctg agcgcactca tattagtcgc
    26641 ctttatttta gcaacactgt ttctaaaatt cgatcgttta attgctgtgc ttggcggtgt
    26701 taccccattt ttaattgcga ttgtcattat gattgcggtc tactatttca caacgagtca
    26761 tcttgatttt actgccgcta ataatgatgc tcagattcat aagcagaaat cattatcacc
    26821 tggatggtgg tttgatgcaa ttaactatgc aagcttgcaa attgctgctg ccttcagctt
    26881 cttatcagtg atgggtagta aagttaagta tcgtgactca acgttatacg ggggcttgat
    26941 tggcggttta atcattacat ttttactcat gatgattaac ctaggtttaa tttctcaatt
    27001 cgataaaatt aaacacgtcg acttacctac attaaaatta gcgacacaaa tgtctccgtc
    27061 aatcggtatt attatgtctg tcattatgat acttgtcatc tacaatactg ttgttggatt
    27121 aatgtatgca tttgcgtcac gtttcagcgt tccatttagc agacgttact tcatcattat
    27181 tattacaatg gctgtcatca cttatattag tacatttatc ggtttcattt cattaattgg
    27241 aaaagtattc cctattatgg gattgttcgg tttcatctta ctcatacctg tactctataa
    27301 aggtttaatt aagcgtatta ccggcaaatc tcatatcgat taaaatatct atactattgt
    27361 aaaatttagt acaacacttc aaaatcaaaa aagcgggcag atgaaaagta aaaatctttt
    27421 ccatctgtcc gcttcttaat agaactgtta tttcccaagt atttgttgac cagccgttaa
    27481 tccagtttct gtaatttcat gaccattcac ccaaacttct tcgacttgtg ccccacgtgt
    27541 cttaaacaag ttaatgactt gttcacttgc agctaatggt acaattggat catgtttccc
    27601 catagaaagc aacacactga catctgataa attcttcgtt gatgttactt caattggata
    27661 taacggtgca tataacaatg cttttttaaa tggtgcttct gaacgcaaca ttaagttaat
    27721 tgctatattt gatccatttg aaaatccaac aagcacagcc ttttcaatat caaattcata
    27781 acgttcagca gcttctttaa tgaacgttaa caattcttgt ccacgaaatg ccaaatcttc
    27841 ttcatcataa acaccttcac caagacgttt gaaataacgg ttcatcccat tttctgaaac
    27901 ttgtcctcta atacttaaca agtgataatt ttcattcaat gcttcgccta atggcaataa
    27961 atcgaactca tcaccacctg taccatgcaa caatattagc gttggcgcac ctttttgtcc
    28021 ttcacgaaaa atatgttcca tcacaaatcc tcctcattcc aattaatcat gttgacgctt
    28081 cgtattaaaa ggtctaactt ccgattctat atattctctt ttattttcta aaaatggtgg
    28141 taatgataac ccttcgccta atgtttcata aggttcatct tccataaatc ctggtccatc
    28201 tgttgaaatt tctattaaaa tatgccccac acgtgcatat aatgcttcaa aatagaaacg
    28261 attaatgatg cctgagttgt taatacctac ctctttatat ttcgttgccc acgcttctat
    28321 tgcatcatga tctttcacac gaaatgacac atgatgtacc tcaccataac cttgacgtgc
    28381 tgctggccct ttatcatctt ttattaagat tacctggcca ccattgcctc cttcgccaac
    28441 ttcaagtaat gcgacattat cttcatgcgc aatagttgtc ataccgtaaa cagtctctaa
    28501 aatattttta aagtcgtcaa aataacttac tttaatttca atgggtccta atccataaat
    28561 cgctttatct actggaaccg gtccattctt ccaaggtaca ccaggtgcta caccttcatt
    28621 taactcatct gaaattaatt gatacacttg gccatcgact tcttcaaatg gcaacacttt
    28681 tttaccaaat agttcttgaa taccttcgtg tttgacacca aactcatcaa agcgctgttc
    28741 ataatatgtt aatgcgtcat cgttaggcac tctaaaagac ggtcttgtaa tagaatttgt
    28801 tccagcctgc cctttaggaa tatctgggaa atcgaagaat gtcatatctg tacctgctga
    28861 acctacatca tctgcaaaaa atgtatgata cgtataaata tcatcttgat tgactgtctt
    28921 tttaactaag cgcatgccta gtacttctgt aaaaaattta taattacgtt ctgcattatc
    28981 tgttattgca gtaacatggt gaatacctaa taattcatga ttatttgcca ttttatatac
    29041 cctctttgtc tttttagtgt atttatctcg aaatcgagat attttaatgt aaatttttag
    29101 tgcacgcctt acacttctgt agattgtgca cttagtttct taaacgcttg ttgtaagatt
    29161 gttaattcat cctttgttaa cacatcaaac gcttttgtta atgtctcagc atgcttaggg
    29221 aaaatatctg ccatttgact ttgacctttt tcagttaaac aagccatata tacacgttta
    29281 tcatctttat ccttttcacg tgtaatccaa cctttgtcct ctaattgact tacaacatat
    29341 gaaatgctgc tacttgcaat taatacgcgg tctctaatac gttgaattgg ttgcggacct
    29401 ttattataaa gcaactcaag cactgcaaat tcagtaatat ttaatccata acgttttacg
    29461 tcttcttttg tgatttgctc taatgtgtct aatgctctat tcattccgac aaagacattg
    29521 agcgattgtt tcgttcgatc catatcatca ccaacttttt cattttattt cgatttcgag
    29581 ataaattata tagctgaata gatttaatgt caagatacgt gttttcatct ttatttcaaa
    29641 ctgcgcttaa taaaaacgac tacataaatg tggcaatgtc gtcacatgac tgtcatgcac
    29701 ctttgacttc gtttaagtta aaatagaata gggaaatact ataatcaatc atgataggag
    29761 ttgatatgta tgagtaacct tgaaattaaa caaggcgaga acaaattcta tattggtgat
    29821 gatgaaaatc atgctttagc tgaaatcaca taccgttttg tggataataa tgaaattaac
    29881 attgatcata caggcgtatc tgatgaactc ggtggtcaag gtgttggcaa aaaactagtt
    29941 aaagcagttg ttgaacatgc tcgcgaaaat catttaaaaa tcattgcctc atgttcattt
    30001 gccaaacata tgttagaaaa agaagattca tatcaagatg tatatcttgg ttaaataaat
    30061 tttgcgatgg tgcaactgtg ccatcgcttt ttatttgttc gcatcaatat aaaattgcaa
    30121 aacgactagt tattttgcat ttcaaacttt atgctgtcaa ttcattttct tttctggtat
    30181 actttttata ctaacttata gaaaaataga aaaagaggcg atgcataatg gcatttcacg
    30241 ataaaacagc aacacaagtg acaaacattg aactgaacgt aagagactta gacttaatga
    30301 caacatttta caaaaacatt ttaggactat ccgttaaaag ttctgacgat aacacaaccg
    30361 tattatctgt tgggactggt ggccatactc taacgttaca tttattagaa gacggccgtc
    30421 agacttcccc acgtgaagca ggactttttc atatagcatt tttattacca actactgagg
    30481 atctagctaa cttcttatat ttcgtggcac aaaaaaatat gggcattggc gctggtgatc
    30541 atttagtcag tgaagcttta tatttcaacg accccgaagg taatggtatt gaagtctatc
    30601 gcgatagacc ttcatcttca tgggaatggc aaaatggcaa agttaaaatg gatactttag
    30661 aagttgatag ccaaacttta ttaacacatc gtactgatga aggttggcaa ggaatgccag
    30721 caaaaggcat gattggacac ttacatttaa aaacacatga tttagacgca gcatatcaat
    30781 gttacattga acaattagga ttccaacatg tgtctgattt tccacgtgcg ctatttatgt
    30841 caacgaatca ctatcaccat catattgccg ctaacacttg gcaatctaat caagcaagac
    30901 aaaacaatgc acaaagttat ggattaacac atgttgatat ttatcaaccc gacgcctcaa
    30961 cacatacatt tacggcacca gaagggtttg gcatcacagt tcattcaaat actgaccttg
    31021 ttccagaaaa ataaacatcc atactttatt aatacaattt tttcacgcaa aagcctgcga
    31081 ttcatttatg taatcgcagg cttttttatt gctaactttt taattttata tatttagaca
    31141 tacggtattc tatttattct tttggtccaa cccattcaat aacatcttca taagcttggc
    31201 gtgttttatt tttcggtgga tcttgttgtc tgtagccaaa tgcaaccatc actgataaac
    31261 caaattgctc agtatctaag atacctttat ttgctaaaat gtctgtcact gtatccagac
    31321 taaaaccttc catcgggcat gaatcaatac ctaataatgc agctgtcgtc atcatattgc
    31381 ctaatgcgat atacgtttgt ttacttgacc aatcatacaa ggcttgatca ttatcggaaa
    31441 tatgaaaatc tgcttggaat gcatcgaatt tttgttcaac agctggaatc gtttgtgcct
    31501 catatttttt aatatctctt aacatatgtt gtacatacgg tgatcttgac gttacatttt
    31561 tacgcgcaaa aattagcaca aaatggctcg ctgtatctaa ttgctttgct gcgccccaac
    31621 tgtgcgcttt taattcatca cgtaacgctt gatcttgaat cacgacaaac ttccaaggtt
    31681 ctaacccaag agaacttgga gacaatctac ctgactctaa tattgtttca aaatcttctt
    31741 tcgaaacttt cttttgtgga tcgaattgct tagtcgcatg tctgaaatga aatgcatcca
    31801 taattgtttg attcatattg ctcattgaac atagcctcca atttttatat ttattactat
    31861 acaaattata cttcatgttt taaaaagact aaagtaatcc gtttgcaatt cactataact
    31921 tgtgtacatg ttataagttt tctgcaataa aacacacttt tgaattttgg aaaatttagt
    31981 gttataatat atttgtgata tttttcacaa ttaaattgtg gcgtgatttt aatgtacata
    32041 atctttaatt tcactcattt acttttcaat cttttaaaag cgaggttttt aataatgaca
    32101 aaaattatgt tctttggtac gcgtgattat gagaaagaga tggcattaaa ttggggaaaa
    32161 aagaataatg tcgaagtaac tacttctaaa gagctattat caagtgctac agtcgatcaa
    32221 ttaaaagatt acgatggcgt aactacaatg caatttggta agttagaaaa tgacgtttat
    32281 cctaaattag aatcttacgg tattaaacaa attgcacaac gtactgctgg atttgatatg
    32341 tatgatttag atttagctaa aaaacacaac attgtgatat ctaacgttcc tagttattca
    32401 cctgaaacaa ttgcagagta ttctgtttct atcgccctac aattagtgcg tcgcttccca
    32461 gatattgaac gccgtgtaca agcacatgat tttacttggc aagcagaaat catgtctaaa
    32521 ccagttaaaa atatgactgt tgcaattatt ggtacgggtc gtatcggtgc tgctacagct
    32581 aaaatatatg caggatttgg tgctacaatt acagcttatg acgcctatcc taataaagat
    32641 ttagactttt taacttataa agatagtgtt aaagaagcta ttaaagatgc cgatattatt
    32701 tctttacatg ttccagcgaa caaagaaagc tatcatttat tcgataaagc aatgtttaat
    32761 catgtgaaaa aaggtgcaat cttagttaac gcagcacgtg gtgcagtcat caatacacct
    32821 gatttaatcg ctgcagtgaa cgatggtact ttgttaggtg ctgcgattga tacttatgaa
    32881 aatgaagcag catacttcac aaatgactgg actaataaag acattgacga taaaacatta
    32941 ttagagttaa tcgaacatga aagaatttta gtaacaccac atattgcttt cttctctgat
    33001 gaagcagtac aaaaccttgt tgaaggtggt ttaaacgcag cattatctgt cattaacact
    33061 ggtacatgtg aaacacgttt aaattaatat atatttaaac aggctgggac ataaatccct
    33121 aaaaaacagc agtaagataa ttttcaatta gaagatatct tactgctgtt ctatatttat
    33181 acaatacttc gtattgaatg gcttcgctat gcccatctgg cacattactg taaaattcta
    33241 taaatagaat ttttgatgat gggtcccttc ctagggtgcc gtctcagcct cggtcttcga
    33301 ctggcactgc tccctcagga gtctcgccat taatactacg tattaacatg taattttact
    33361 tttaaataat ttaaaaaata agacactttg ccaaacttgc acataaatgt ttaattcaat
    33421 aatttgaatt ttctgtgttg ggtcccttcg tataatttaa taaataccac taaactaaat
    33481 taatgaagtg ccttatgtat aaaaattata acttgatcca acttacacta ccaatagaaa
    33541 cttctgttag aattcctcaa attgatattt cgcgatatgt taatgaaatt gttgaaacga
    33601 tacctaatag tgaattcgat gaattcagac accatcgtgg cgcaacatct tatcatccaa
    33661 aaatgatgta aaaattatct tatatgcata cactcaatct gtattttctg gtcgtagaat
    33721 agagaaacta cttcatgaca gtattcgaat gatgtggtta gctcaaaatc aaacaccttc
    33781 ttataaaact attaatcgtt ttagagtaaa tcctaatact gatgcattaa ttgaatcttt
    33841 atttatccag tttcatagtc aatgtttaaa gcaaaacctt attgatgata attcgatttt
    33901 tattgatgta caaaagtaga agctaatgcc aataggtata catttgcgtg gaagaaaagt
    33961 attcaaaatc atgaattgtt ttattttgta tatctgtatc aaaatcgatt tgattaaaat
    34021 ccgctttatt ttatcatcta ttcaaatgat tttagtgcgc ttattttact atggcattat
    34081 tgtctaacct gtttgagata tattaatatt tgatgattcg tattcagagt tttcatttaa
    34141 catgtattta gtatcataat agctacttca ttgatgatgt actacctact tgttcaatac
    34201 ttcttgttcg ataattgtta aaacaccttg cttatcgtta cttggagcga cagcagaggc
    34261 aatattgaac aattcttcat catgactatt ttccatcaca taactatgct tagcgaacgc
    34321 tagcatatct ttatcattat tcgcatctcc aaaggccatg agctctgaag gagacatttc
    34381 ccatttatct aacaatcgtt ttaatgcctg ccctttagtc atgtttggca taataatatc
    34441 aatactatcg tgcccacttg agacaagttt aatatcattg ctgaattgcg ttgctacttc
    34501 ttcgtcaaca ttcggatgcg tctcacgatt aatattaaat gctattttga cataatcatc
    34561 ctcaggtaat tgttgtagac tatcaatttc ttttaactga tgataataaa atctcgtatc
    34621 ttctttaaat gcttcagaag tatgtttcaa aatatacgcg cttttcaaac cacagatgac
    34681 gagttgatca ataccttggt tcatatttaa gtaatcgaca acctgttgaa acacctgacg
    34741 attaaagctt ttataattat ataactcatt gcctttataa ataactgcac cattttcaga
    34801 aataaaatac atatctctat ccccgaaaat agacttcaac ttcgcatatt gattgccact
    34861 cgcagcaata aatgtaatat ctctatttct aagttcagta aaaatcgctt caaatcttgg
    34921 tttatcgtat gtctttttcg aatctaaaaa cgtcccgtcc atatctaccg caatagcctt
    34981 aaccatgatt atcctcctca ttgctctttt agtcgtcttc attatatcca tctcatgaca
    35041 agcaatgaag tttgtcatac cacaatgaac ctatattcac attttgaaat tgctttcata
    35101 tatgcaaaac acattacact ggatatagca ttcgaaggcg aacataaatt tcagaatatt
    35161 gtaaaaatat aacgatatat ttatcatttg gacaaaatat agtgtgat
//
LOCUS       DAPSKH010000028        34817 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPSKH010000028 DAPSKH010000000
VERSION     DAPSKH010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 34817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34817
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.028"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..332)
                     /gene="deoC"
                     /locus_tag="RPH49_001370"
     CDS             complement(<1..332)
                     /gene="deoC"
                     /locus_tag="RPH49_001370"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDY5124527.1"
                     /translation="MNSAKLIDHTSLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVK
                     YAAERLADSEVLVCTVIGFPLGASTTATKAFETEDAIQNGADEIDMVINIGALKDGRF
                     DDVQQDIEA"
     gene            647..1357
                     /gene="deoD"
                     /locus_tag="RPH49_001371"
     CDS             647..1357
                     /gene="deoD"
                     /locus_tag="RPH49_001371"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDY5124528.1"
                     /translation="MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFND
                     VRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVN
                     LYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSD
                     TFYNADPTFNAAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPE
                     ERQNSFTQMMEIALEIAE"
     gene            complement(1479..1922)
                     /locus_tag="RPH49_001372"
     CDS             complement(1479..1922)
                     /locus_tag="RPH49_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDY5124529.1"
                     /translation="MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKF
                     EELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDF
                     TNISKQLEKAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS"
     gene            complement(2122..2535)
                     /locus_tag="RPH49_001373"
     CDS             complement(2122..2535)
                     /locus_tag="RPH49_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase DCC family
                     protein"
                     /protein_id="HDY5124530.1"
                     /translation="MPIVYYDGNCIYCYNYVIWLIQHDLPRNYRFATLKGEVGQQFFK
                     QHPEAANKNSVILQKGDRIYFESQAIIQLITALPNRTKLLGVGLWLVPKPVRNFGYRM
                     FANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD"
     gene            complement(2991..4364)
                     /locus_tag="RPH49_001374"
     CDS             complement(2991..4364)
                     /locus_tag="RPH49_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EVE domain-containing protein"
                     /protein_id="HDY5124531.1"
                     /translation="MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRA
                     FKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKR
                     SEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIY
                     THTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNST
                     VIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGL
                     KSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPD
                     FSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLE
                     GYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTR
                     IVKVKHD"
     gene            complement(5038..5268)
                     /locus_tag="RPH49_001375"
     CDS             complement(5038..5268)
                     /locus_tag="RPH49_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124532.1"
                     /translation="MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAM
                     LTFKDKQISASLKFSALLINVLPLCGTFVASN"
     gene            complement(5299..6237)
                     /locus_tag="RPH49_001376"
     CDS             complement(5299..6237)
                     /locus_tag="RPH49_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I mannose-6-phosphate isomerase"
                     /protein_id="HDY5124533.1"
                     /translation="MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGT
                     SEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYE
                     HENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEF
                     YFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNA
                     PLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMI
                     VDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV"
     gene            complement(6673..7338)
                     /locus_tag="RPH49_001377"
     CDS             complement(6673..7338)
                     /locus_tag="RPH49_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5124534.1"
                     /translation="MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQG
                     MKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKE
                     ANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAA
                     GSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNYQEFQIISGEQDIKDALTQFEI
                     EKD"
     gene            7490..7810
                     /gene="czrA"
                     /locus_tag="RPH49_001378"
     CDS             7490..7810
                     /gene="czrA"
                     /locus_tag="RPH49_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)-responsive metalloregulatory
                     transcriptional repressor CzrA"
                     /protein_id="HDY5124535.1"
                     /translation="MSEQYSEIHTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGH
                     ISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPK
                     ESGL"
     gene            7812..8792
                     /gene="czrB"
                     /locus_tag="RPH49_001379"
     CDS             7812..8792
                     /gene="czrB"
                     /locus_tag="RPH49_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc efflux transporter CzrB"
                     /protein_id="HDY5124536.1"
                     /translation="MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLA
                     NSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFV
                     ISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAF
                     LHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEG
                     TPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLE
                     NIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH"
     gene            9058..10149
                     /locus_tag="RPH49_001380"
     CDS             9058..10149
                     /locus_tag="RPH49_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDY5124537.1"
                     /translation="MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKY
                     VQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVK
                     FTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYAD
                     STHLIGIAITTQSIIIIVVLLIKAIITWLLLIPIFNFMTSFVESTNDKVKTHLANGFK
                     AMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTI
                     ILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKDKKVVTEPKNTKVENDKVATSVE
                     TKTEKAQDSLNDNTTKTMTSDKPEDNQPK"
     gene            complement(10664..10768)
                     /locus_tag="RPH49_001381"
     CDS             complement(10664..10768)
                     /locus_tag="RPH49_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124538.1"
                     /translation="MLLLERTSMSDFEMLMVVLTIIGLVLISNQGHKK"
     gene            complement(10866..11027)
                     /locus_tag="RPH49_001382"
                     /pseudo
     CDS             complement(10866..11027)
                     /locus_tag="RPH49_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002504693.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            11445..11603
                     /locus_tag="RPH49_001383"
     CDS             11445..11603
                     /locus_tag="RPH49_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001792784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDY5124539.1"
                     /translation="MRKSSDALFNLLTQSFELIEGVHNELVTDNLKTVMYKPRKERTN
                     GRINRRFK"
     gene            complement(12263..13120)
                     /locus_tag="RPH49_001384"
     CDS             complement(12263..13120)
                     /locus_tag="RPH49_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDY5124540.1"
                     /translation="MDNVKAIFLDMDGTILHENNQASTYTKDVINRLREKGYKVFLAT
                     GRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQIINLAKRQQIY
                     YEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEG
                     EYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMI
                     AHFGIHQDETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAK
                     YLAKHFLAD"
     gene            complement(13188..13970)
                     /locus_tag="RPH49_001385"
     CDS             complement(13188..13970)
                     /locus_tag="RPH49_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124541.1"
                     /translation="MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTL
                     LNILNAYEPATTGGVNLFGEMPGKVGYSAETVRQHIGFVSHSLLEKFQDGERVIDVVI
                     SGAFKSIGVYQDIDDEVRNEAHQLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQ
                     PQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLK
                     DGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE"
     gene            complement(14202..16007)
                     /gene="glmS"
                     /locus_tag="RPH49_001386"
     CDS             complement(14202..16007)
                     /gene="glmS"
                     /locus_tag="RPH49_001386"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDY5124542.1"
                     /translation="MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTV
                     FKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGV
                     IENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALG
                     LLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKD
                     EVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEG
                     NLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMP
                     LLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAG
                     PEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIM
                     EQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIE
                     DGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTP
                     LVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE"
     gene            16688..18226
                     /locus_tag="RPH49_001387"
     CDS             16688..18226
                     /locus_tag="RPH49_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDY5124543.1"
                     /translation="MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFID
                     NGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPM
                     LLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPIM
                     KFIMHILSVAVESLVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQS
                     ILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLF
                     IAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFV
                     VATLIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETS
                     SSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGIND
                     ITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKK
                     DDQA"
     gene            18261..20393
                     /locus_tag="RPH49_001388"
     CDS             18261..20393
                     /locus_tag="RPH49_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDY5124544.1"
                     /translation="MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKG
                     VESYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQLQTIDLSVEEQKVIIIYALI
                     QAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKR
                     EFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPY
                     QLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLDQIYD
                     VTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTL
                     VDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEI
                     AFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLK
                     SLDLSQYDGIISTVNLDIDTPYLMVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMN
                     DKDDVHVETKDIDGNTSFENEQTSNLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKI
                     VSTEVKQWQTYIADYLYQCDAIKDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNM
                     IKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLES
                     IDTFMENPQELETLLRSKFLERIKKQFI"
     gene            20405..20839
                     /locus_tag="RPH49_001389"
     CDS             20405..20839
                     /locus_tag="RPH49_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDY5124545.1"
                     /translation="MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAM
                     KDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGK
                     DGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA"
     gene            20839..21945
                     /locus_tag="RPH49_001390"
     CDS             20839..21945
                     /locus_tag="RPH49_001390"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDY5124546.1"
                     /translation="MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDH
                     QYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFA
                     SFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNEN
                     ILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFA
                     GKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSD
                     EVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTGDQETVEKN
                     NYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS"
     gene            complement(22264..29580)
                     /locus_tag="RPH49_001391"
     CDS             complement(22264..29580)
                     /locus_tag="RPH49_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HDY5124547.1"
                     /translation="MNLFRQQKFSIRKFNVGIFSALIATVTFISINPTTASAAEQNQP
                     AQNQPAQPADPNAQPNANAGAQANPTAQPAAPANQGGQADPAANQGGQANPAGGAVQP
                     AAGTTQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANA
                     PAGAQPAAAVAANGQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVN
                     GYSLINNGKIGFVNSELRRSDMFDKNNPQNYQARGNVAALGRVNANDSTDHGNFNGIS
                     KTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPT
                     DADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKAT
                     NNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLK
                     NMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNIANIDTPKNIDFN
                     EKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAE
                     YNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDAKAQEK
                     ITAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTAQGVTTEKDNGIAVLEQDVI
                     TPTVKPQAKQDIIQAVTTRKQQIKKSTASLQDEKDVANDKIGKIETKAIKDIDAATTN
                     AQVEAIKTKAINDINQTAPATTAKAEALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIE
                     RINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVKQAATARK
                     AQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQ
                     SRVKPAADTEVDNAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNS
                     AVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTSEEQQAAKDK
                     VDQAVVTANADIDNAAANSDVDNAKTTNEATIAAITPDANVKPQAKQAIADKVQAQET
                     AIDANNGATTEEKVAAKQQVQTEKTTADTAIDGAHSNAEVEAAKNAEIAKIEAIQPAT
                     TTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVIQANSNIEAANSQND
                     VDQAKTTGETSIDQVTPTVNKKATARNEITTTLNNKLQEIQATPDATDEEKQDAETEA
                     NTENAKANQAITAATTNAEVDEAKTNAEAAINAVTPKVMKKQAAKDEIDQLQAAQTAV
                     INNDQNATNEEKEAAIQQLATAVTDAKNNITAATDNNGVDTAKDAGKNSIQSTQPATA
                     VKSNAKNDVDQAVTTQNQAIDNTTGATTEEKNAAKDLVSKAKEKAYQDILNAQTTNDV
                     TQLKDQAVADIQGITADTTIKDVAKGELTAKANEQKALIAQTADATTEEKEQANQQVD
                     AQLTQGNQNIENAQSIDDVNTAKDNAVQAIDPIQASTDVKTNARAELLNEMQNKITEI
                     LNDNTTTNEEKGKDIGPVRAAYEEGLNNINVANSTGDVTTAKDAAVQKVQQLHANPVK
                     KPAGKTELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNIDQSSTDDYVD
                     AAVRDGKAKINAVKTFSEYKKDALAKIADAYNAKVNEADNSNASTSSEIAEAKQKLAE
                     LKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNIS
                     ADTNATQDEKQQAIKQVDQNVQTALESINNGVDNSDVDDALTQGKATIDAVQVDATVK
                     AKANQAIDAKAQETKESIDQSDQLTAEEKTEALATIKQITDQAKQGITDATTTAEVEK
                     AKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDSDATTEEKEVFTNALEEI
                     LSKATEDISDQTTNAEIATVKNSALEQLKAQRINPEVKKNALEAIREVVNKQIEIIKN
                     ADADASAKEIARTDLGRYFDRFADDLDKTQTNAEVAELQNVTIPAIEAIVPQNDPDAN
                     HSSSDNNDATANTNVNAEPDNAGQPNVTESTDNANADTSSTTTNNHNDAATGETTATS
                     TNNSSTDDANDKPTANNNSSVDASIDNSATGNGTTDKPATTESTEKTSSADSKDNASV
                     NDSNQNAEVNNSAESQPTNGKVAQPKSENKAKVEKDGRDSTNQSMVESTTETLPSADI
                     TEPNVPSNTSKDKEESTSNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASS
                     EAKDKMTSTEDSQKADMATADTKDNQASIGSSADANNKATQNDGANASPATVSNGSNS
                     ANQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGM
                     AFLIRRFTKKDQQTEE"
     gene            complement(29857..31212)
                     /locus_tag="RPH49_001392"
     CDS             complement(29857..31212)
                     /locus_tag="RPH49_001392"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDY5124548.1"
                     /translation="MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPR
                     VLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISAS
                     HNPVADNGIKFFESDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQK
                     YLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKC
                     GSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQE
                     LNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVM
                     MDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDV
                     KEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLD
                     K"
     gene            complement(31239..32171)
                     /locus_tag="RPH49_001393"
     CDS             complement(31239..32171)
                     /locus_tag="RPH49_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HDY5124549.1"
                     /translation="MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTI
                     QDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQ
                     EKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQ
                     TVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNL
                     QVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDL
                     DGISESTEKTVKINLPEHVTKAQPSETKAYINVK"
     gene            complement(32173..32982)
                     /locus_tag="RPH49_001394"
     CDS             complement(32173..32982)
                     /locus_tag="RPH49_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDY5124550.1"
                     /translation="MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQL
                     LKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFL
                     KRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNIS
                     QELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEV
                     SDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK"
     gene            complement(33171..34079)
                     /gene="rocF"
                     /locus_tag="RPH49_001395"
     CDS             complement(33171..34079)
                     /gene="rocF"
                     /locus_tag="RPH49_001395"
                     /EC_number="3.5.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginase"
                     /protein_id="HDY5124551.1"
                     /translation="MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLIPRLKQLDL
                     DVNDKGDIKVSAVDIEKFQSEQNGLRNYDEIIDVTQKLNKEVSASIENNRFPLVLGGD
                     HSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLE
                     FNINTIKPENIVLIGMRDLDKGERQFIKDKNIKTFTMADIDKLGIQTVIENTLDYLKT
                     HNVDGIHLSLDVDALDPLETPGTGTRVLGGLTYRESHFALELLHQSQSVTSMDLVEVN
                     PLIDSNNHTAEQAVSLVGTFFGETLL"
     gene            complement(34223..34295)
                     /locus_tag="RPH49_001396"
     tRNA            complement(34223..34295)
                     /locus_tag="RPH49_001396"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34260..34262),aa:Lys,seq:ttt)
     gene            complement(34299..34373)
                     /locus_tag="RPH49_001397"
     tRNA            complement(34299..34373)
                     /locus_tag="RPH49_001397"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34339..34341),aa:Gln,seq:ttg)
     gene            complement(34383..34466)
                     /locus_tag="RPH49_001398"
     tRNA            complement(34383..34466)
                     /locus_tag="RPH49_001398"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34430..34432),aa:Tyr,seq:gta)
     gene            complement(34495..34570)
                     /locus_tag="RPH49_001399"
     tRNA            complement(34495..34570)
                     /locus_tag="RPH49_001399"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34535..34537),aa:Val,seq:tac)
     gene            complement(34578..34649)
                     /locus_tag="RPH49_001400"
     tRNA            complement(34578..34649)
                     /locus_tag="RPH49_001400"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34614..34616),aa:Glu,seq:ttc)
     gene            complement(34651..34725)
                     /locus_tag="RPH49_001401"
     tRNA            complement(34651..34725)
                     /locus_tag="RPH49_001401"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34691..34693),aa:Asn,seq:gtt)
BASE COUNT        10482 a         6277 c         5387 g        12671 t
ORIGIN      
        1 gcttcaatgt cttgttgtac atcatcaaaa cgcccatctt ttaatgcgcc gatgttgatg
       61 accatgtcaa tttcgtctgc accattttga attgcatctt ctgtttcaaa tgctttcgtt
      121 gcagttgtcg acgcacctaa tgggaatcct attaccgtac aaactaacac ctctgaatca
      181 gctagtcgct ctgctgcata tttaacatgc gttggattca cacatacaga tttaaaattg
      241 tatgctttcg cttcatcgat gatttgatcg atttgcgtac gtgttgactc aggcttcaat
      301 gaagtgtgat caatcaattt tgcactattc attttctatc tcctccttta tggttgatta
      361 taaaaatacg gttgtaaatt agttgattga gcgtcaggtt catttaaata tcaggttaga
      421 tgttcgcttt ttatgtaacc gcatacatat actattacat taattcattt cccataaaca
      481 aacaatacaa ttgaacgtga tatcttcatt atgaacgatg acttgacaac aagctaatca
      541 ggattatatt tttataattc tttaattcta tagtacaaaa attcgcaaaa aagggaaaca
      601 aatgttatct taaaattatt aatgaatatt aaggagaaga taacaaatga caaaaggtac
      661 accacatatt caaccaaatg gagtaaaaat tgctaaaaca gtattaatgc ctggcgatcc
      721 gctacgcgca aaatatattg ctgataattt tttagaaaat gttgaacaat ttaacgatgt
      781 acgtaacatg tttggttaca ctggtacata taaaggtaaa gaagtttctg taatgggttc
      841 tggtatgggt attccaagta tcggtattta ctcatatgag ttatacaact tctttgatgt
      901 agacacaatc attcgtatcg gttcttgtgg cgcattacaa gaaaatgtta acttatacga
      961 tgttattatt gcacaagctg catcaactaa ttcaaattat gtagatcaat acaatattcc
     1021 aggtcatttc gcgcctatcg ctgacttcga gttagtaact aaagctaaaa atgtcgctga
     1081 ccaaatcggt gctactacac acgtaggtaa cgtattatct tctgatacat tttacaatgc
     1141 cgatccaaca ttcaatgctg cttggaaaaa aatgggtatt ttaggtatcg aaatggaatc
     1201 agctggttta tatttaaatg cgattcatgc tggtaaaaaa gcacttggta ttttcacagt
     1261 aagtgatcat attttacgtg acgaagctac tacacctgaa gaacgtcaaa attcatttac
     1321 acaaatgatg gaaattgctt tagaaatcgc agagtaactt atttaaattg actttaattg
     1381 ctctttaaca atgagattaa actcaaaaag ccaacacatt ctgggcgtat tccccattta
     1441 tgtgttggct tttatttata ttattactta tctgtagatt agcttaagta agatttaaac
     1501 atccaattat gtttatctac tgatgtttgc atacctataa acatatcttc tgatacatca
     1561 tcgccagcat taccagcaat ttcaatcgct ttttctaatt gttttgagat atttgtgaaa
     1621 tcttgagata attcttcaac catttgttct gcagagtaac ctttcgcagc ttctttaaca
     1681 attgattgct ctaagcattc agttaatgta cctacagggt ttcctcctac cgctaaaatt
     1741 ctttcagcta attcgtctac atattggctt gcttcattat ataattcttc aaatttaacg
     1801 tgtaatgaga agaagttagg ccctttcaca taccagtgga aattatgtag ctttgtgtat
     1861 gctactgtcc agtttgctac ttgttgattc aattctttta caacatcttg ttgattactc
     1921 atatttaata cactccttaa aattgtctac gtcttacttg tttatattaa ttattatatt
     1981 ataatgattc taatctgtaa agtgttttca ctctcttttt tataattatt ctaatttaat
     2041 tgtgaggtgt ttggcttttt aaatgcctaa attttaatcc atcatctagt atgtctatta
     2101 tcaattagca actatgtttt atcaatcagt aagttttact ttcgcattat catctaaaaa
     2161 gaacgatttt tcataatcat ttggttggtg ccatgttgtt ttccacattc tatttctatt
     2221 attagcaaac attcgataac cgaaattacg gactggttta ggtacaagcc ataaacctac
     2281 gcccaataat ttagttcgat taggtagtgc tgtgattagt tgaataatcg cctgcgattc
     2341 aaaatatata cgatcacctt tctgtaaaat cacactattt ttatttgccg cttctggatg
     2401 ttgtttaaaa aattgttgtc caacttcacc ttttaacgta gcaaatcgat aatttcttgg
     2461 taggtcatgt tgaattaacc aaatgacata gttataacaa tatatacagt ttccatcata
     2521 atatacgatt ggcataattt attcgctcct tcaatagtac ttatagtcat ttttcctaat
     2581 ttaaaaacat ttaaacaagg ttgtcacttg ataagtcctc gcgacacgaa attgccataa
     2641 aatttatttt tcagttttat atttattgta taatgtattt tttatttact ttaaatttct
     2701 caatctacag tgtaatctta tttcttatta ttaacttagc gtttagtcgt tcgccttatt
     2761 caacatacca ctggaaactc atataaagtt ttaattcagt aacataaatt catttatatt
     2821 catatactgt ctttatcatt tattaaaata aaaacgagta atctatcata agctcttaat
     2881 tagctcttat ggttgattac ccgtcatttt ttctttatac ggttattcaa atatgcaatt
     2941 atgcaatttt taatctttcc ttacttcttt tcaaaaacta ccatatatca ttagtcatgt
     3001 ttgactttga ctatacgtgt gtattttaaa aactgctctg aatatttctc cttaatttcc
     3061 tctaaactat catatgtaat acctacaata tgccaattag gattgaaata atagaaagaa
     3121 tctttttgtc gtgaccattt aatcatatta ccgtctttat tataacgtgg taatgttacc
     3181 tcatagcctt ctaacacatt aatatacgtt tggaaaatgt ctgtatctat acgattaaaa
     3241 ttatcaataa ctaaataact tttatccttt ttaggcatta actgagtaat aaatccttca
     3301 cgatagtata atgcccctgt ttcatttggt aaatacttgc cataaagcat atcttctgaa
     3361 aaatcaggat gacctgttgt tataacagga tttgcattcg ctttttgcaa taagtcatta
     3421 gccgctttta agccttcttc ttttcgatct acaacaagta aaataaatgg ctttaacgct
     3481 tcttcttttt cactttcaag catatctggt ttttgaacca tttcaaatgg agatttcaat
     3541 ccattattat cgctcatttc aataattgca tcatactgtg cttgtgacat acttgcaata
     3601 gcctgttttg cattttcttg aaggaaatat aagtttttca atttaggatg cttatttaat
     3661 gtacttaatg taatcggcgt aatgtctttc tcataagaca cttcaatcac tgtactattt
     3721 gttctaccag gaattggtgg tttttcatga atatgctttg atacttctcc aattccaacg
     3781 acagattgat tttttgttcg attataaaaa ataatattgt cgccttcttc taactgagta
     3841 taaaaatgat aaccattacg tttaataccg ttgtacgtgt gcgtataaat cgtatattgg
     3901 tttccaggtt caaattcttc agtttcagct aaaaagaaat aacgtggtat cttaatttcg
     3961 cctttaccaa gaccacttat taaatcaaac tcttctgcag tgatttggtt gaacaatgtc
     4021 tctttcatat tactcatacg aaattccaaa gcttcactac gctttagata atctgctgtt
     4081 aatggtttca attgttcatt aaaacgaaac tgtacacgta ttttattttg tgcacctgtt
     4141 tcaacactaa taatttcacc acatccaagt agtccagtat ccgtctgaac ttgataaaag
     4201 atgacttgat ctcctacttt agccttttta aacgctctaa atccttgaga tgggttaaaa
     4261 tgtgcgcctg attcaaataa agctgtttgt cctactaacg gttcattatg attccaacgg
     4321 ttatatccac aattcaacca aaaataattc gtttctgctg tcatcttaat actccttaac
     4381 ctgaataaat tttagaaaca ctatgaatta cattctttta gtgtttctta tgcagttgga
     4441 cgcgtatgcg atcaactgta taccctttgt tcactgcgat tttaatcgca tttcctataa
     4501 cactgtagcg cccaggacat taatttacgt cccagaccct taacgttttc ccttttaagt
     4561 aagtcgaact attttgcttt acaacaagtg cgactctata tgcagttgga cacacacata
     4621 cgagcgactg tatacctttt aatcagtttt ctatatttta tttattatat ctgtcttaat
     4681 gataaaaatt gttacaaaca gtttaacata tttagctacc tattttgcat ataaaaaaca
     4741 tgcttggata cactatgcaa taaaaattac aaatttatat atgataccac tatgcttgct
     4801 tatctctata gcgccattga tacacatttt taaatatcta tactgccgtt agaattttag
     4861 catgtcttaa ttttcattaa atataaaata cttcatttta tataaaccaa caaaaacccc
     4921 ctcactacta tgcaagtgag aggttatgtt gatgtgcttt attttcatca atgtcattaa
     4981 cacaatcata tttcttctgt taatgcactg tattatattc aaacgcgcta tcgacaatta
     5041 atttgaagct acaaaggtac cgcataatgg cagcacatta attaacaatg cgctaaactt
     5101 taatgaggcg ctgatttgct tgtctttaaa agtcaacata gcactgataa ttcctaaaat
     5161 agctactata cgtggaattg tcatgctcgg atactgcggt atatgtaaga aagcaccaag
     5221 acctgctatc acaccacata ctaacgcaat atatagaaat tgcttcaaat cattcactcc
     5281 taaattgtta ttacactatt acacatagct aatcatcaat gtgaaatcac cttcaaagac
     5341 actatccaaa tcttcagaag tcaaaataaa gtttgtacca gtagtcagtt tgaaaatttc
     5401 accatcgaca atcatttgcc cttcaccttc caacactgta actaaacaga actctctagg
     5461 cttcatataa tttaacgtgc cagaaatttc ccatttaacc aatgtaaaga aatcattcga
     5521 tacaatgtgt gtacacttat ggttttcaat aatttcactt tcaggcaaaa tattaggtaa
     5581 tggggcattg tactgaataa cgtctaaagc tttttcaata tttaacggtc tatcattata
     5641 ttgattatct tgacgattga aatcataaag tctatatgta atgtctgacg attgcatcgt
     5701 ttcgtatgct agtattcctg aagaaatagt atgtactgtt cctgctggaa taaaatagaa
     5761 ttctccaggt tttactttaa tatatctaag tatcgactct atcgttccgt gttgaacatg
     5821 attcgcaact tcttctctag actctgctaa tgtccctata actatttctg catcttcttc
     5881 agcatctata atataccaac attcagattt gccatattgc ccgttttcat gctcataagc
     5941 ataagaatta tcagggtgca catgaataga aagtgattct cttgcatcca ctattttagt
     6001 tagaagcgga aaatctttgc ttgggaaatc accaaacaat tcacgatgtt ctgaccaaat
     6061 acggtctaat gtttgacctt gatatggtcc attaataatc tcgcttgtac catttggatg
     6121 tgctgacaca caccaacatt ccccagttgt atcattgtct aattgatatc caaactcact
     6181 tagacgttga ccgccccata attttgtttt taaaattggt tgtaaaaata atggcattgt
     6241 tgcacctcca ttgtgattaa gtaagcaata gaactctgat gttgttgttc cattatattt
     6301 tgattttgtt ctcatttaca tcgtattata aatttccaca tttcaaatta actattagtg
     6361 attgtaccat atttactaac attgcagtac tgccaattaa agcgcttcac ttaaatttac
     6421 agtactttaa catttttaaa aattaatagc atagagatta tctctctctt acatttgtac
     6481 acatttccct ttaaatttac tcgcccatta taccaattaa taaacaactt taatagttgt
     6541 gccatacatt gttcaaattc tttgtaaaat gcatagacaa tacgtactta ttcatactta
     6601 taattcatca ttttcaaaaa aataacgagt tacgaaaacg taacccgctt caaatcatat
     6661 ttactatcct tattaatcct tttcaatttc aaattgagtt aaagcatctt taatgtcctg
     6721 ctcaccacta ataatttgaa actcttggta attaaaatga ttggatgtga caatttcttt
     6781 taatactgtc gcaacatctt ctctaggaat ttcaccttta ccatcaaaat attgtgcagc
     6841 ttctatcttt ccagatcctg ctgcatttgt aagtgcccct ggatgtaaaa ttgtataatt
     6901 caaacctgaa cgtcttaaat agtcatcagc gtaatgttta gctattgtat atggctttaa
     6961 atcaccgcta tcatcaaaag cctgacgtct cgaatcatat gttgaaacca tgacatagtg
     7021 tttaatatta gcctctttac tcgcaatcat tgatttaaca gcaccatcta aatcgacaat
     7081 aattgtttta tctgctcccg tgttccctcc agaacctact gaaaagataa ctttatcgaa
     7141 tggtttaaac gtctcagtta aagtctctat tgaatcattt tcaacatcaa caagaattgc
     7201 tttcatacct tgtgatttta acgcattaag ttgatcggat tgcctaacac cagcagtaaa
     7261 tggtacattt tcttttgcta attgttgcac tagtaacgaa cctacaccgc cattagcacc
     7321 tataaccaaa atattcattt acaacactct cctatttatt attccctatg ccataccact
     7381 ttatgagata tgtaaaactt gttacaacta taaaaatcaa ttgacatact actgagaacg
     7441 tattaaatta atatatgaac aaatattcat atgaaaggat tgtcatataa tgtcagaaca
     7501 atattcagaa atacatacag atacattaga acgcgtaact gaaattttca aggcattagg
     7561 cgattacaat cgaatacgta ttatggaatt gttatcagtc agtgaagcaa gtgttggtca
     7621 catttcacat caattgaatt tatctcaatc aaatgtctcg caccaattaa aattacttaa
     7681 aagtgtgcat cttgtgaaag caaaacgaca aggccaatca atgatttatt cattagatga
     7741 catccacgta gcaactatgt taaagcaagc catacatcac gcgaatcatc ctaaagaaag
     7801 tgggttataa tatgtctcat tcacatcatc atcatgacca tatgcatagt catgtaacta
     7861 caaataataa gaaagtattg tttatatcgt ttttaataat cggtctatat atgtttatcg
     7921 aaatcatcgg cggtctcctt gctaacagct tggcattact atctgacggt atccatatgt
     7981 ttagcgacac attctcatta ggtgttgcac ttgtcgcatt tatttatgct gaaaagaatg
     8041 ccacaactac aaaaacattt ggttataaac gtttcgaagt actcgcagcg ttatttaacg
     8101 gtgtaacgct ttttgtaata agtattttga ttgtttttga agcgattaaa cgtttctttg
     8161 ttccttctga agttcaatca aaagaaatgt taatcattag tattatcggt ttaattgtca
     8221 atatcgttgt tgcattcttt atgtttaaag gcggcgacac ttcacacaat ttaaatatgc
     8281 gtggtgcttt tctacatgtt atcggagact tattaggttc agttggcgcc attactgcag
     8341 ctattttaat ttgggcattt ggatggacaa tcgccgaccc tatcgcaagt attttagttt
     8401 ccgttattat tttaaaaagt gcttggggta tcacaaaatc ttcaattaac attttaatgg
     8461 aaggcacacc aagtgatgtt gatatagatg aagttataac tactattaaa aaggattcac
     8521 gaatacaaag tgtgcatgat tgccatgttt ggacaatttc aaatgatatg aatgcattga
     8581 gttgtcatgt tgttgtagac catacattga caatgaaaga atgtgaatta ttattagaaa
     8641 acattgagca tgatttatta catttaaata ttcaccatat gactattcaa ttagaaacgc
     8701 ctaatcacaa acatgatgaa tcgattatat gttcaggaac acatagtcat tcacataacc
     8761 atcatgctca tcatcacgca catgtacatt aataatttta acctactgcc attgcatcga
     8821 ttaaactttt caatggcagt agttttttta tgtctttatg gcgacttgtt tggtctttga
     8881 tgacgcaatg tttattaaca aattttcaac tattatttct tacattagtc atatttttga
     8941 caatttacta ttataattct ctaactttag tcactttaat taatttttat tagatattaa
     9001 tatgaaaata acgtgttttt tgttattgta tttatatgaa gaaaaggagg caccactttg
     9061 tttacttact ttaaatcagc atttaaaaat gctaaaccac aattattaat aacattgata
     9121 tatgcactta tagcatttgc tgtaattgca gttgtatatt tacttgctaa tttccagctt
     9181 gctaagtatg tacaaactat tgcaatttat tcacaatttg ggcaaaaacc accagtagat
     9241 gcatatttaa aagttatcgc tgtattactt atagcagctg tagtttcact gtttgtttta
     9301 gttcaaattt ttatcggaat tacaaatgtt atgaaacgag caatgagtca tgaaaaagta
     9361 aaatttaccg atttatttat tgcatttaaa aaaggtaatt atttaaagag cgttctgatc
     9421 ggtcttgtat ctatagcaat gattatcgtt ctttcacttc tgacatcatt actatacaaa
     9481 ttattttctc cagtatcaga aatgattatg aattcagtac aatcatcata tgcagatagt
     9541 acacacctga ttggtattgc tattacaact caaagcatca taatcattgt tgttttattg
     9601 attaaagcaa ttattacttg gttattgtta atacctattt tcaactttat gactagtttc
     9661 gttgaatcaa ctaacgataa agtaaaaaca cacttagcta atggatttaa agcaatgaaa
     9721 aatggtcaaa aaacattttt caaatttttc attggaatac tattattaaa cttaattatt
     9781 attttattta aaacacctgt tggttacttg atttcattta atacgcaatc actctctcaa
     9841 agtgttgcag aaaatatcat aagagtttat acagtaatga caattatttt attcgttgtt
     9901 attcatgcaa tcattttaat gggtatcgtt caatattact taaaacgtgg tcaaaaaatt
     9961 actaaagata aagtaaaaac agctgacaag gataaaaaag ttgtcactga accaaaaaat
    10021 acaaaagtag aaaatgataa agtggcaaca tctgttgaaa caaaaacaga aaaagcacaa
    10081 gattcattaa atgataatac aacaaaaacg atgacttcag ataaaccaga agacaatcaa
    10141 ccaaaataaa ttttagagcc ccttacaact ttagttgtta ggggctctta tgcagttgat
    10201 gcgtagcatc caactgtatt cctctatttt tcaactttag ttgttagggg ctcttatgca
    10261 gttgatgcgc agcatccaac tgtgttcctc tatttttcaa ctttagtagc tgataccgaa
    10321 ataacatgat gctaatttca tggcatgccg aaaaaatata tgaagaggtc tgcagtactt
    10381 tttatatagt ccgtgattac attctatact ttttattgtt ttttgttgta ttgatagttg
    10441 gctttattat ttctgattat gttcagaact acaattcata agaaaaatgt gttaaaatat
    10501 atttgtagta agtagaagta aaagatgaaa atctttaact cttgaaacac aaaaagggca
    10561 acactcggaa acatgttacc ctaatgagcc cgttaaaaag acggtgacct tatattttat
    10621 ttaaaaatag ccttcaaaaa tgccggtcaa agcgaataga aggttatttt ttatggcctt
    10681 gattactaat caatactaaa ccaatgattg ttaatacaac catcagcatt tcaaaatcag
    10741 acatgctagt cctttctagg agtaacaact ataaccatag gcatcacccc tttattaaga
    10801 gattagccac catctatcca acttgctcaa taaatattat aacatgcacg cttttaaaca
    10861 gtaattcata gtataagttt tttcatttcg ttaataactc gataaacagt tgagcgacat
    10921 acccctgtct gactagctat ttcttcccct gctatctttt gttcatcata taaaaattta
    10981 atttctcact ttttatgctc tggtaaagag gggcgcccgc tttttcggct gataagctcc
    11041 cttcaaagta gacattgaaa aataaaaatt tcgaaagaga aatcgtcagt ctattattga
    11101 caattattat ccgatcatcc aaaagatact ttcagacact agtaaacaat agttctacta
    11161 taagcatata ttttggcaat atttgaaggt taaacatgga ttaacctgtg cctattctac
    11221 atttagagct atccttaagc atgatgaatt taatcgttat tttatgaaaa gttatcaaca
    11281 gatgtcgcct aaagtttcaa cgagattcga gacaaaaccc agtcatcaag tacagtttga
    11341 ctggaaagaa accattaatt ttaaaaagaa agataatcaa atgatttcac taaatatagg
    11401 agtgctacta ctttcttatt ctcgttttat aatcatgcat gacaatgcgt aaatcaagtg
    11461 atgccttatt taatttatta acacaatcgt ttgagctaat agaaggtgta cataatgaac
    11521 ttgtaacgga taacttgaaa acagtcatgt ataagccaag aaaagaacgt acaaatggtc
    11581 gaataaatcg tagatttaaa taattcgctg atggttttaa ttttaaagta aaaccttgta
    11641 tttccggccg ccctagaaaa aaggtaaagt tgaatcaata acgaaatcat tagatgaaat
    11701 tcatgcttat caagacgaat tgtatttgga aaaagttcct aagttttttt atcttaatga
    11761 acgatttaac tactaagttc atactagtac aggtaaattg cctattactg cctaagagaa
    11821 agaaaaaatt ttcttacaac cactacagaa tgtgaatgta aaaaactcat ataaagtgaa
    11881 acatatctta cttatggaat gaaatgtttg atgatctcaa aattgcaaat gcgagtttgg
    11941 agttgttagg gtcccttatg catgccctta gcgcaaacac tctacttaaa gaaacggtag
    12001 ttgttatagt atacttaaat gcataaacca tataaaagcg gatataacta tgacattcgg
    12061 ttcaattgta gctatactct gtgccctatt tgtgattttc ttcattccat atatggagaa
    12121 gaaagacaaa aagaagaaat aacactagta cctggattac tagcatacaa aagagcagta
    12181 aggcattttc taacagaaaa taactttact gctctttgta tattgctcat caactatttt
    12241 ggatttatta ttaaaacacc aattaatcag ctaaaaaatg ttttgctaaa tattttgctg
    12301 cgccatcctc ttcattcgtg tatgccgtta catctgaagt taatgcttgg atttcagggc
    12361 gtgcattttt catagcaact gtataatgac caaattcaaa cattgctctg tcgttatcac
    12421 tatctccaat aactaaagtt tcatcttgat gaatgccaaa gtgtgcaatc atttctttaa
    12481 taccagtgcc tttatcagtt tgataagcca ttgtttccgc attaaatctt gatgaatttg
    12541 aaacactaat ctgtagttgc acatgatttt gctttaattc atctctaaat gctgttattt
    12601 tttctaaatt agaactgaat agataaattt ttgaatattc accttcagga aacttagtta
    12661 cccaatctat cttaccagca agcgcatctt gtcttgaaga ccattcacta tgacttacgc
    12721 cattaatagg atcttgacta cgaatcatat ctcgcatcca tgtttcatct tcttttaaag
    12781 aaactctatt accttcaaaa ggaaatacct cataataaat ttgttggcgc ttagctaaat
    12841 taataatttg ttgcacttga gccaatgata aaccatgttt gaagataatt tctccatcta
    12901 cttctccaat tgttccattt gaactaatga tgccattaac cgcaaaatct tgaggtacaa
    12961 gttgatgtat ttcagaatgc gaacgtcctg ttgccaaaaa tactttatat cctttctctc
    13021 tcaatcgatt aatgacatct ttcgtatacg ttgatgcttg attattttca tgtaaaattg
    13081 ttccatccat gtccaaaaat attgctttta cgttatccat attgccctcc actgtccatt
    13141 ttatcttaat taaattttgt cattattact tattatttgc aaaatattta ctctaacatt
    13201 gccatagaaa atcgattatt ccatctttga actgctacat ttttctggaa aaatcgtgac
    13261 atgttttcag atgtcaaaat atcatctatt aatccttgtt gtacactttc cccatctttt
    13321 aatagcaaaa ttttagtaaa gttaccagta atttcttcaa taaagtgcgt cacataaatc
    13381 atcgcaagcg ttggatatga atctgacaat gagtcaagta tattcaatag tgactcacga
    13441 gcaataaagt ctaaaccagc tgctggctca tctaaaatta aaacctgagg ttgccccatt
    13501 aaagctcgtg caatcatcac tcgttgtttt tcacctgtag ataaataacc aatatattgt
    13561 tgcgctttag cagatattcc aactaattta agtaattgat gtgcttcatt acgtacctca
    13621 tcatcaatat cttgataaac accaattgat ttaaaagcac cgcttatcac cacatcgatt
    13681 actctttcac catcttgaaa cttttccagt aaactatgag atacaaaacc tatatgttgt
    13741 cgtacagtct ctgcagaata ccctaccttg cctggcattt caccaaatag attaacaccg
    13801 ccagttgtcg caggctcata tgcatttaat atatttaata gcgttgtctt accagcacca
    13861 tttaaaccat atagaatcca tttgtcacct ttagcaattt gccacgaaat attttttaaa
    13921 attgtttttc cttgcttcat tcgcccaatt tgatctaatt gaattaacat gcgaggtcac
    13981 ccctttattg ctactccata cttctcataa aatcatatta acataacacc cttaattgtc
    14041 agactattta aataaataaa acacttcatt tttacgcatt tctgccaaat taagatgaag
    14101 taaaagctaa gtcgacctaa aaaagcaccc ttctagtcga ttaatctaaa agggtgccat
    14161 atactttaat tttaatacat gattgattct aaaaaagtga attattccac agtaacagat
    14221 ttagcaaggt tacgtggttt atccacatct aaatctctgt gtaatgctgc ataatatgaa
    14281 atcaattgta atgcaactac tgaaactaat ggtgtcaata attcatgtac atgtggaatg
    14341 acataagtgt cgccttcttt ttcaagacct tccatagaaa tgatacatgg atgtgcacca
    14401 cgtgctacta cttctttaac gttaccacga attgataaat taacgttttc ttgagttgct
    14461 aaagcaacaa ctggtgtgcc atcttcgatt aaggcaattg taccatgttt aagttctcca
    14521 ccagcaaaac cttctgcttg aatgtaagaa atttctttaa gttttaacgc accttctaaa
    14581 cttacgttat agtcaatagt acgtccgata aagaatgcat tgcgtgttgt ttctaagaaa
    14641 tctgtagcaa tttgttccat aattggtgca tcgtcaacaa ttgcttctat tgctgttgtt
    14701 acttttgcta attctctcaa taaatcaata tctgcttcac gaccgtgctc ttttgcaacg
    14761 atttgagaca agattgataa tactgcaatt tgtgcagtat atgcttttgt agatgcaact
    14821 gcgatttcag gacccgcgtg taataacaat gtgtggtctg cttcacgtga taaagttgaa
    14881 cctgcaacat tagtgattgt taatgattta tgacctaatt tattagtttc aactaatacg
    14941 gcgcggctat ctgcagtttc acctgattga gaaatataaa cgaacaatgg tttttcagat
    15001 aataatggca tgttgtagac aaactctgat gcaacgtgta cttcagttgg tacgccagcc
    15061 catttttcta aaaattcttt acctactaaa cctgcatggt agcttgtacc tgctgcaata
    15121 acgtaaatgc ggtctgcttc tttaacatca ttgatgatgt cttgatcaat tttcaagtta
    15181 ccttctgcat cttgatattc ttgaataata cgacgcatta ctgctggttg ttcatgaatt
    15241 tcttttaaca tgtagtgtgc ataaacacct ttttcagcat ctgatgcatc aatttcagca
    15301 atatatgaat cacgttctac aacgtttcca tctgcatctt taataataac ttcatctttt
    15361 ttaacaataa cgatttcatg gtcatggatt tctttatatt cgcttgtcac ttgtaacatt
    15421 gcaagtgcgt ctgatgcgat aacattgaaa ccttcaccaa cacctaataa taatggtgat
    15481 ttatttttag caacatagat tgtgtctttg tcttcagcat ctaataaacc taatgcatat
    15541 gaaccatgta ataatgacac aacttttgta aatgcttctt cagttgaaag tccttgattt
    15601 gaaaagtatt caactaattg aacgataact tctgtatctg tttctgaaat gaatgataca
    15661 ccttgtaagt attcaccttt taactcttca tagttttcaa taacaccgtt atgaactaga
    15721 gtaaaacggc catttgatga ttgatgtgga tgagagtttt catgattcgg tacaccgtgt
    15781 gttgcccaac gtgtgtgacc gattccaaca ggtccatcaa aatcgctact atcagcaact
    15841 ttacgtaatt ctgcaatacg acctttttct ttaaatacag ttgtattatc atcatttact
    15901 actgcgatac ctgcagagtc ataacctctg tattctaatt tttctaaacc ttttaataat
    15961 aattctttgg cattatcata gccaatgtaa ccaacaattc cacacataac gacattttcc
    16021 tccatattgg aatagtacgc gtaaattatg atttattgcc gataatttag attgacaatc
    16081 tgctttcata atataaatag gaacatgcta tcatcgcatt catccataac aaattaagca
    16141 tagttatttt tacaactata caaattgctc acactgtact ttccatatta atatttttta
    16201 tattcaattt ctggcgatct tattaacttt gtccattaag tcaccctaat gttttactta
    16261 ataagctaac gaatgagcca catccgggat agcatccgcc gatctattcg atcactatcc
    16321 tcctcgtcta caaatacata tattgcactc tataaaggcc actcatatat taacctttaa
    16381 tcttcaaata caaatattta tttgcacagg cgctttaact gtactgccga actttccccc
    16441 tttccattaa tcattattgt acaacggtgt tgttttgttt tgcaaatatt ttcacaataa
    16501 aattttaaaa atcctaaaac aatttttttg ttttactttt tcaaaatatc tatactgtca
    16561 cattgatgac actttattta attttgtcac atttattttg acaaagttga tttttgttta
    16621 tattgagtaa caagtaacgt ctctatacac tatatatagt cacatatatt aaaaaagagg
    16681 tgtaaatatg tcacaaactg aagagaaaaa aggaattggt cgtcgtgttc aagcatttgg
    16741 atcattctta agtagtatga tcatgccaaa cattggcgct ttcatcgctt ggggttttat
    16801 cgcggccatt tttatagata atggatggtt acctaacaaa gatttagcta ctttagcagg
    16861 accaatgatt acttatttaa tcccattatt gatcgcattt agtggtggtc gtttaattta
    16921 tgatttacgt ggtggtatca tcgcagcaac agcaactatg ggggtcatcg ttgcattacc
    16981 tgatacacca atgttacttg gtgcaatgat tatgggtcca cttgttggtt ggttaatgaa
    17041 aaagacagac caattaatcc aacctagaac accacaaggt tttgaaatgc tatttaataa
    17101 tttttcagct ggtattttag gatttatcat gacaattgca ggatttaaaa ttttagcacc
    17161 aattatgaag tttatcatgc atattttatc agtagcagta gaatcattag tgcatgcaca
    17221 tctacttcca cttgtaagta ttttagtaga acctgcaaaa atcgtatttt taaacaatgc
    17281 gattaaccat ggtgtattca caccgcttgg tgcagatcaa gctgcaaaag ctggtcaatc
    17341 aattttatac acaattgaat ctaaccctgg accaggttta ggtatcttac ttgcttatat
    17401 gatttttgga aaaggcactg caaaagcaac gtcatatggt gctggaatta tccacttctt
    17461 aggtggtatt catgaaattt atttcccata tgtattaatg cgtcctttat tatttatcgc
    17521 tgttatttta ggtggaatga ctggtgttgc aacttatcaa gcaacaggat ttggatttaa
    17581 aagtcccgcg tcaccaggtt catttatagt ttactgttta aatgcaccta gaggtgaatt
    17641 cttgcacatg ttactcggtg tgttccttgc tgcacttgta tcattcgttg tagctacttt
    17701 aattatgaag ttcactagag aaccaaagca ggatttagaa gctgcgacag ctcaaatgga
    17761 aaatactaaa gggaaaaaat caagcgttgc ttctaagtta gtatcttctg ataaaaatgt
    17821 taatacagaa gaaaatgcta gtggtaatgt tagtgaaaca tcttcatcag atgatgatcc
    17881 tgaagcgcta ttggataatt acaacactga agatgttgat gcacacaatt acaataatat
    17941 aaatcatgtt atttttgcct gcgatgcggg tatgggttct agtgcaatgg gtgcaagcat
    18001 gttacgtaat aaatttaaaa aagcgggcat taatgatatt acagttacaa atactgcgat
    18061 taatcaattg ccaaaagatg ctcaattagt tatcactcag aaaaaactaa ctgatcgtgc
    18121 tattaaacaa acaccaaatg ccatccatat ttcagtggat aatttcctta attcaccaag
    18181 atatgaagaa cttttaaata atctaaaaaa agatgatcaa gcataataat taaataaatt
    18241 aaaaaatgga ggataccgcc atgttattga gtacacgtga aaaagaaatg atagccctat
    18301 tgattaagta ccacggtcaa tatatcacta tacacgacat tgctcagcaa cttgcggtgt
    18361 cctctcgtac tattcaccgt gaattaaaag gtgttgaatc atatttaact tcattttcat
    18421 taactttaga acgtgcaaac aaaaaagggc tacgcattgc tggcgcagat tctgatttaa
    18481 atgatttgaa gcaatcgatc gcacaacttc aaaccattga cttatctgtt gaagagcaga
    18541 aagtaattat tatatacgct ttgatacaag ccaaggagcc agttaaacaa tatagtttag
    18601 cgcaagaaat tggcgtttct gtccagactt tagcaaagat gttagatgat ttagagctcg
    18661 atttaaataa gtaccaacta tctttatctc gaaagcgtgg cgaaggtatt tacttggtag
    18721 gtactgaatc aaagaaacgt gaatttttaa gtcaattaat ggtgaataac ttaaatagta
    18781 ctagcgttta ttcagtaatt gaaaatcatt ttgtctttca ttcattaaat caaatccaca
    18841 aagactttgt tgacttagag cgtattttta atgttgaaag actattaatg gactacctaa
    18901 gtgccttacc ctaccaactt accgaatcaa gttatttaac tttaactgtc catatcgtgc
    18961 tctccatttc acgtataaaa aatggagagt atgtcgcatt aaacgatgat atttatgatt
    19021 ctgtacaaaa cacatttgaa cacaaagtag caagcgaact tgctgataaa cttgatcaaa
    19081 tatatgacgt cacgtttaat caggcagaaa ttgctttcat tactatccat ttacgtggag
    19141 ctaaacgaaa aaatcttaat gatacatcat taaataatcg ttgtgaagaa aacaaaatta
    19201 aagcgtttgt taacaaagta gaaatgattt caggtatgac atttgcagat ttggatactt
    19261 tagtagatgg actgacgcta caccttaatc ctgcaatcaa tcgtttgcaa gctaatatcg
    19321 agacctataa tccgttaaca gacatgatta agttcaaata tccaagacta tttgaaaatg
    19381 taagattagc tttaaatgat tgttggcctg atttgatttt tccagagagt gaaattgctt
    19441 ttatagtttt acactttggt ggctcgatta aaaaccaagg taatcgattt ttaaacatat
    19501 tagtcgtttg cagcagtggt atgggaacta gtcgtctatt atcaactcgt ctagagcaag
    19561 tttttagtga gattgagcgt attacacaag catcagtcag cgatttgaag tcactagatt
    19621 taagtcaata tgatggcatt atttctactg tgaatttaga catcgacacc ccctatttaa
    19681 tggtaaaccc attattacca gatagtgata tcagttatgt cgcacagttt ttaaatacaa
    19741 agtctacgtt ccaagagacg catgataaat catcaaacat gaatgataag gatgatgttc
    19801 atgttgaaac gaaagatatt gatggcaaca catcttttga aaatgaacaa acttcaaact
    19861 taacttcagt tttcgaaaaa catttaagtg acgaaaaatc agagcaatta atgcatcata
    19921 tgcgttcggg tttaactttg cttgattcag tgaaaatagt tagtaccgaa gttaaacagt
    19981 ggcaaacata tatcgcagat tatctatatc aatgcgatgc aataaaagat ccaacgtcat
    20041 tcgctgaact actagagcaa cgattgattg acaatccagg atggatatta agtccatatc
    20101 ctgttgcaat accacaccta agagacaata tgattaaaca ccctatgatt ctaatcacag
    20161 ttttagaaga accgttaaca ttgcctagta ttcaaaatga caatcaaaca attaaatata
    20221 tgatttccat gtttattcct gacaatgatt ttatggcatc actggtaagt gacttgtccg
    20281 aatttttaag tttgaaatta gaatctattg atacttttat ggaaaatcca caggaacttg
    20341 aaacattatt aagaagcaaa tttttagaac gaattaaaaa acaatttatt taggagtgta
    20401 caaaatgagc gaattattta gtaatgacaa tatcttttta aatgtaaatg ttaacagcca
    20461 aaatgaagca attgaaaaag caggtaaagc cttagttgat agtggtgctg taacagatgc
    20521 ttatattcaa gcaatgaaag atcgtgagca agttgtatca acatttatgg gaaatggctt
    20581 agcaattcct catggcacag atgaagctaa aacaaatgtg attcactcag gtttaacatt
    20641 attacaaatc cctgaaggcg ttgactggga tggcgaagta gttaaagttg tcgtgggtat
    20701 tgctggtaaa gatggggaac atttagactt gttatctaaa attgcaatta catttagcga
    20761 agaagaaaat gtggatcgta tcgttcaagc aaaatctgca gaagaaatta aacaagtatt
    20821 cgaggaggca gatgcataat gaaagcagtt cactttggtg ctggtaacat aggtcgtggt
    20881 ttcattggtt atattcttgc agacaacaat gttaaagtaa catttgcaga cgtcaatgaa
    20941 gaaatcatta atgctttagc tcatgatcat caatacgatg ttattttagc tgatgagtct
    21001 aaaacaacga cgcgcgtgaa taatgttgat gcaattaatt caatgcaacc ttctgaagcg
    21061 ttgaaacaag caattctaga agctgatatt attacaacag ctgttggtgt taacatacta
    21121 cctattattg ctaaatcttt tgcgtctttc ttaaaagaaa aaacaaacca tgttaatatt
    21181 gttgcttgtg agaatgccat tatggcaact gatacattga aaaaagcggt acttgatatt
    21241 actggccctc ttggtaacaa tattcatttt gctaactcag cagttgatag aattgtacca
    21301 ttacaaaaga atgaaaatat attagacgtt atggttgagc cattttacga atgggttgtt
    21361 gaaaaagatg catggtatgg tccagaacta aaccatatta aatatgttga tgatttaaca
    21421 ccatatattg aacgtaaatt attaactgtg aatacaggac atgcatattt agcgtatgct
    21481 ggtaaatttg caggtaaagc taccgtatta gacgctgtaa aagatagttc aattgaagct
    21541 ggcttacgcc gtgttttagc tgaaacaagt caatatatta ctaatgaatt tgattttact
    21601 gaagcggaac aagctggtta tgttgaaaaa ataatagacc gtttcaacaa ttcttattta
    21661 tctgatgaag tgacacgtgt cggacgaggt acgttacgta aaattggccc taaagataga
    21721 attataaaac cattaacata tctttataat aaagatttag aacgcactgg tttattaaat
    21781 acagctgcat tgttattgaa gtatgatgat acaggagacc aagaaactgt tgagaaaaat
    21841 aattacatta aagaacacgg tttaaaagcg tttttaagcg aatatgctaa agttgacgat
    21901 ggcttagccg atgaaataat tgaagcgtac aattcacttt cataatttat tgagctttgt
    21961 ttgaaacaag aagtttccaa cgttattcgt taacaatcag taataatgta gtagttccgt
    22021 tgaattaaca atattaaatt tctgaacata aaaaatactc ccttcaacat agacacttaa
    22081 cttgtgttat gtatgaaagg agtatttttg cgttaataat ttgttttatt ttcgagccac
    22141 agccacctat tcaatggcta ttggtcatta ctaaaacaaa ttcatattaa ctgttagact
    22201 tggttactta gtaaggaata tttccctatg aaataactag atgttcacat tcttgaataa
    22261 attttattct tcagtttgtt ggtctttctt agtgaatctt ctaattaaga atgccatacc
    22321 tgcacctaga gctaattcag catatggtaa atcgtcatta tgtgacatac cagtatctgg
    22381 taaagtttta gcttgttgtt taggcttatt aacttttcct tgttggtctg attttgcatt
    22441 tgctttgttt tcttcaggct tagttacatt aagcatatct tgattagcac tattgcttcc
    22501 atttgaaact gtagctggag atgcattggc accgtcgttt tgcgtagctt tattgtttgc
    22561 atctgcagat gaaccaattg atgcttgatt atcttttgta tctgctgttg ccatgtcagc
    22621 tttttggcta tcctcagtcg aagtcatttt atcttttgct tctgaagatg cagatgttga
    22681 tggtttattc gaaacttcag tatcagcttt gcttggcgat ttatctgctt cgttagatgc
    22741 aacgttagtt tcagacttaa gttgtcctgc atcagtttga tttgacgtac tttcctcttt
    22801 atcttttgat gtattagaag gtacatttgg ttctgttatg tctgctgaag gcaatgtttc
    22861 agttgttgat tcgaccatac tttgatttgt tgaatctcta ccatcttttt ctaccttagc
    22921 tttattttca gattttggtt gtgcaacctt gccattagtt ggttgagatt cagcactatt
    22981 attcacttca gcattttgat ttgaatcatt tacagatgca ttatctttgc tatcagcaga
    23041 tgatgttttt tctgtgctct cagttgttgc tggtttatca gttgtgccat tacccgttgc
    23101 cgaattgtct attgatgcat ctacactaga attgttatta gctgtcggtt tatcatttgc
    23161 atcatcagtt gatgaattgt ttgttgatgt tgctgttgtt tcacctgttg ctgcatcatt
    23221 atgattattt gtcgttgttg aagacgtatc tgcgttggca ttatctgttg actcagttac
    23281 attaggttgt ccagcattgt ctggctctgc attaacattt gtatttgctg ttgcgtcatt
    23341 attatctgaa ctgctatgat tagcatccgg atcattctga ggcacaatcg cttcaattgc
    23401 aggtatcgtt acattttgta attctgcaac ttctgcattt gtttgtgttt tatctaaatc
    23461 atcagcaaat ctgtcaaaat atctacctaa atccgtacgt gcaatttctt tcgccgatgc
    23521 atctgcatct gcatttttaa ttatttctat ttgcttgtta accacttctc taattgcttc
    23581 taaagcattt ttcttaactt caggattaat acgttgtgct ttaagttgtt caagcgcact
    23641 atttttgaca gtagcgattt ctgcatttgt agtttgatca gaaatatctt cagttgcttt
    23701 tgataaaatc tcttctaaag cattcgtaaa tacttctttt tcttcagttg tagcatcaga
    23761 gtcgacattt acacctgctt caatctggtc tagtgcagtt tctaattctt cgatagcttt
    23821 ttgtttttct gttgagtcga tttgaatgtt atcaaatgct tcaagtcctt gagctttcgc
    23881 tttttcaact tcggcagttg ttgttgcatc agtaatacct tgtttagctt gatctgtaat
    23941 ttgtttaatc gttgctaatg cttcagtttt ttcttcagca gttaactggt cactttggtc
    24001 aatagattct ttcgtttcct gtgctttagc atcaatcgct tggtttgctt tagctttaac
    24061 agtagcatct acttgaactg catcaattgt cgctttacct tgtgttaatg catcatcaac
    24121 atcactatta tccacgccat tattaatgct ttctaacgca gtttgaacat tttggtcaac
    24181 ttgcttgatt gcttgttgtt tttcatcttg tgttgcatta gtgtcagctg aaatattatt
    24241 tttcttctga tctgcatagg catataaatc tgttgtagcc gattcttttt tacctgttgg
    24301 aatcgtataa tcgttaatat tatctaagtc attatgaatt tgtacttcta tgtcatcttt
    24361 agaagtagct tgattaacgt tttgatccgc agtttgtttc aattcagcaa gtttttgttt
    24421 cgcttcagca atttcacttg aagtcgatgc gttagagtta tccgcttcat taactttagc
    24481 attatatgca tctgcaattt tagctaaagc atcttttttg tattcactaa atgttttaac
    24541 tgcattaatt ttagcttttc catctctaac cgcagcatct acatagtcat cagttgaaga
    24601 ttgatcaata tttgttttcg cttgatttaa ctctgtatca acttcttgtt ttgcatcatt
    24661 aatttcttgt tgtgacgcat ttggcgtttg ttcaatttgt gttttcttat cagctgcagc
    24721 ttgatctaat tctgttttac ctgctggttt cttaacagga tttgcatgaa gttgttgaac
    24781 tttttgtact gctgcgtctt tagcagttgt tacatcacct gttgaatttg caacattaat
    24841 attatttaaa ccttcttcat atgctgctct aactggccct atatctttac ctttttcttc
    24901 attggtagtc gtattgtcat taaggatttc agttatttta ttttgcattt catttaacaa
    24961 ttcagctctt gcattcgttt taacatctgt tgatgcttga attgggtcga tggcttgaac
    25021 tgcattatct tttgcagtgt ttacgtcatc aattgactgt gcattttcaa tattttgatt
    25081 accttgcgtt aactgtgcgt ctacttgttg atttgcttgt tctttttctt ccgtagtcgc
    25141 atctgcagtt tgtgcaataa gtgctttttg ttcatttgct tttgccgtta attcaccttt
    25201 agcaacatct ttaattgtcg tatcagcagt aataccttga atgtcagcaa ctgcttgatc
    25261 ttttaattgc gtaacatcgt tagtcgtttg cgcatttaaa atatcttgat atgctttttc
    25321 tttagcttta gaaactaaat cttttgctgc atttttctct tcagtcgttg cacctgtagt
    25381 attatcaatt gcttgatttt gagttgtcac agcttgatca acatcatttt ttgcattcga
    25441 tttaactgct gttgctggtt gtgtactttg aatcgaattt ttacccgcat ctttggctgt
    25501 atctacacca ttattgtcag ttgcagctgt aatgttattc ttcgcgtctg taactgctgt
    25561 tgctagttgt tgaatcgctg cttctttttc ttcatttgtt gcgttttgat cgttattaat
    25621 aaccgctgtt tgtgctgctt gtaattggtc gatctcatct ttcgctgctt gtttcttcat
    25681 aacttttggt gttacagcgt taattgccgc ttctgcatta gtttttgcct catctacttc
    25741 agcgtttgtt gtagctgctg tgatagcttg atttgcttta gcattttcag tattagcttc
    25801 agtttctgca tcttgttttt cttcatctgt tgcatctggc gtagcttgaa tctcttgcaa
    25861 cttgttgttt aatgtagtag tgatttcatt acgcgctgtt gcttttttat taacagttgg
    25921 tgtcacttga tcaatactag tttcaccagt tgttttcgct tggtctacat cattttgact
    25981 attagcagct tcaatgttgc tatttgcttg tatcacagca ttatctacgt ccgcattagc
    26041 cgctgcaatt tcttctgctg taatgtcttg cgtttgagcg attgctgttt tacgttcatt
    26101 cgctttcgta gcaattgctt gtttcgcatt atctttcgtt gttgttgctg gctgaattgc
    26161 ttcaatttta gcaatttctg catttttagc cgcttcaact tctgcatttg aatgtgcacc
    26221 atcaattgct gtatcagctg ttgttttttc agtttgaact tgttgtttcg cagctacttt
    26281 ttcttctgtt gttgcaccgt tattagcatc aattgctgtt tcttgagctt gtactttatc
    26341 tgcaattgct tgtttcgctt gaggtttaac atttgcatca ggtgtaatgg ctgcgattgt
    26401 agcttcattt gtagtttttg cattatctac atcactgttt gctgcggcat tatcaatatc
    26461 agcgtttgca gtaactactg cttgatcaac tttgtctttc gctgcttgtt gttcttcact
    26521 agtcgaatca ttcattgctt cgattgctgt tttacgttca cttgcttttt gagcaatttc
    26581 tgctttagca tccgatttct tagttgttgc cgcttgaact tgattaattg cagcaatacc
    26641 attgtcttta gctgttgtta cagcactgtt tgtatttgca gcatcaagat tcgttcttgc
    26701 ctcttgtttt ttagcatcta attccgtata tgccgcttct ttttcttctg tagttgaagc
    26761 attgctattt tggatttctt gtttacgtgt attatatgcg ttgtctactt ccgtatccgc
    26821 tgcaggttta actcttgatt gtgtttgaat agcattgatt ttatctaata cttttgcttt
    26881 agtatcagcc acttcttgtt gtgatttaac aacttggatg tcatgtaaac cttctgtttg
    26941 agctgcatct actgctgcat ttgcctctgc tacttcttca tctgtagcat ttgaaactgt
    27001 agcattttga gcttttctag ctgtagcagc ttgtttaact tctttataag catccatttt
    27061 agtttgagtt gagtccgtaa tattctcaat tttgaatatt tcttcgtttt taacgcgttc
    27121 taaatcttgt gcagtcgttg tcgcttctat cgctttaaca cctgaaactt tagctgcatt
    27181 aatacgttca atggcctccg ctacttcttc atttgttgta tcaggattta aaggcgcttg
    27241 atcaatttgc gcttgtacaa cttcatcaaa ttcttcaaga gcttctgctt tggctgttgt
    27301 tgcaggtgca gtttgattaa tatcattgat tgcttttgtt ttaatagctt ctacttgcgc
    27361 attcgtagtt gctgcatcaa tatctttaat tgcctttgtt tcaattttac caattttatc
    27421 atttgctaca tctttttcat cttgaagaga tgcagttgac tttttaattt gttgtttacg
    27481 agttgtaact gcttggataa tatcttgttt cgcttgtggt ttaacagttg gtgtaattac
    27541 atcctgttct aacactgcga taccattatc tttttcagtt gtgacacctt gcgcagttgt
    27601 ttgtttatta atttctgcga ttgcattatt tttatcattg ttaattttag ttacaagtgc
    27661 tgccacttca tcttgcgtaa cttttttact ttgttgtgct gctgtaatct tttcttgtgc
    27721 tttagcatct aattcagcaa ttgctgcttg attatcaatt aatgcagctt gtaatttagt
    27781 tactaaacca tcaatatccg cttgagatgc acgatttgca gtttcaacat gattcgcatc
    27841 ttcatttaaa atagtgtctg cttgttgttt aagtttattg tattctgcaa ttgatgctgt
    27901 tgtgtaatga ctattatcaa cttgtgagtt tacttgttgt tgtaacgcat ctttgttcat
    27961 ttcaaccgct actgaaaatg gatctgcagt tagtgtaact tctggttgcg cattattaat
    28021 tacaacatct gaagcagtac gatatgttaa tttttcatta aaatcaatat ttttaggtgt
    28081 atcgatattc gcaatattaa ctttatatga taattttaaa gatttatctg ggaataaaac
    28141 ttctttcgtg tgtgtaccac gagccgttgt cacaccttgg ctagtaaatg ttactttatt
    28201 cgcagtttga tcataattga cagtcatatt tttcaatact gtactgtctt cgttaccatt
    28261 agggaacgta gtagttaacg aatcattaac gtacgttaca ccttgtggta atgttacttc
    28321 gtatttgaat tgatctgctt ttaatgaagc accaaaatta ccattgttac cgatttcagt
    28381 attaatagta tattctttat tgttagttgc tttcggtgct aaatctctat ttttgacata
    28441 taaatgtgat cctgagaata gacctacatt atcaatgaat gaatagtatt tataaccatc
    28501 tttatttgtt gtaattcttg aagcatcagc aactgctgta ttgtcaggaa taaattgtaa
    28561 atctaagcga tcagcatcag ttggcacttt aaataaatgt gcagtaccag tcttagcaac
    28621 atttacagtt gctaattcag tatttttctt agcatcttta ataactaaat ttgttgcacc
    28681 ttgcttacta ttcgtttgca tagtagtaaa gttaataatc aattctgaat ctggctttac
    28741 atttacagtt tttgaaatac cgttaaagtt accatgatct gtagaatcat ttgcattcac
    28801 acgacctaat gcagctacat tccctctagc ttgatagttt tgagggttat tcttatcaaa
    28861 catatcgctt cgtcttaatt ctgagttaac gaaaccaatc ttaccattgt taattaatga
    28921 ataaccattt actttatctg taacagttac agttggatcc tgtctattct catctgttga
    28981 tatggctgga tcatcaaatg ttaatgtagt attaatactg ccttcaccag tattgctagc
    29041 atttggatct tgagtttgtc cgtttgctgc tacagctgct gctggttgcg ctcctgctgg
    29101 agcattcgct ggctgtgttt gatttgccgg tgttgcatta ttattaggtg ttgcttggtt
    29161 atttccttga cctgcttgat ttgcaggtgc tgcttgattt ccaggttgtg cttgtgcagc
    29221 attattcgga tcagcttgat taccttgtcc agctggttgt gttgtacctg ctgccggttg
    29281 tactgcgcct cctgctggat tagcctgtcc accttgattt gctgctgggt ctgcttgacc
    29341 accttggttg gcaggtgcag caggctgtgc tgtaggatta gcttgagcac cagcatttgc
    29401 gttaggctgt gcattggggt cagccggttg tgctggttga ttttgtgcag gctgattttg
    29461 ctctgctgca gacgctgttg tcgggttaat agatataaat gtaacagtgg caattaaagc
    29521 tgaaaaaata ccgacattaa attttctgat actaaatttt tgttgtctga ataaattcat
    29581 taagtcatcc tcctggttga ttattctcgc tgttaaatga tgtcacttaa tcaactgtta
    29641 agatatgtag tagcatctgc gttaaaaaca caaagcaact ctatctaatt aaaattaatt
    29701 ttatcatcat tatatattga gtaccagtgt attttatatt acatattgat tactttgttt
    29761 ttattttgtt tatatcattt tacgtttgta ctataaatta tttctacaaa cacaaaaaac
    29821 cgatgcatac gcatcggctt atttgtaata cagtatttat ttatctaatc ccattttatc
    29881 ttgaaccaca tcagctattt gttgtgcaaa tctttcagca tcttcatcag ttgctgcttc
    29941 aaccatgaca cgaactaatg gttctgttcc agaaggtctt actaaaattc gaccttctcc
    30001 attcatttct acttctactt tagtcataac ttctttaacg tcaacatttt cttcaacacg
    30061 atatttatct gttacgcgta cgttaattaa tgattgtgga tattttttca tttgcccagc
    30121 taattcactt agtgatttac cagtcatctt tattactgaa gctaattgaa taccagttaa
    30181 taaaccatca ccagttgtat tgtaatccat cataacgata tgtccagatt gttctccgcc
    30241 taagttataa ttaccgcgac gcatttcttc tactacatat ctgtcgccaa ctttagtttt
    30301 attagattta attccttctt gttcaagcgc tttgtaaaaa cctaagttac tcataacagt
    30361 agaaacaatc atgtcattat tcaattcttg atttttatgc atttcttgac caataataaa
    30421 cataatttgg tcaccgtcaa cgatttgacc attctcatct actgctatga ttctgtctcc
    30481 atcgccgtca aatgctaacc caaaatcact ttcagtttca acaacttttt ctgctaattt
    30541 ttcaggatgt gtagagccac atttctcatt gatattatat ccatcaggac tacatccaat
    30601 tgtttcagta tctgcttcta aatcaccaaa taagaatggc gctagtgatg atgttgaacc
    30661 atttgcacca tctaaaacaa ttttcaaacc ttcaaagtta acatctactg ttgattttaa
    30721 atagctcaaa tatttttgtg ccccttcaaa gtaatctgaa taatgtacaa tatcattgcc
    30781 aactggtctt ggtaattctg ggttttcttg atccaataat gcttcaattt cattttcttg
    30841 ttcatctgat agtttaaaac catctgattc aaagaattta ataccattat ctgcaactgg
    30901 attatgagag gctgaaatca ttacacctaa ctctgcaccc atatcgcgtg ttaaatatgc
    30961 aacacctggt gttgaaataa tacctaatcg catcacttct gcaccaattg aaatcaaacc
    31021 agctattaat gctgattcta acatttcacc tgaaactcta gtatcgcgac ctacaagtac
    31081 acgtgggtgt ttttcacctt tattatgtgc taaaacatag ccaccgtatc ttcctaattt
    31141 aaatgccaat tcaggtgtta gttcttggtt tgcgacacct cttactccgt ctgtaccaaa
    31201 atattttccc attgtttact ctcctttaat ttagctattt attttacatt tatataagcc
    31261 ttcgtttcac ttggttgtgc tttagtgaca tgttctggta aattgatttt tacagtcttt
    31321 tcagttgatt ctgaaatacc atctaaatct acttctgcat caacttcgct tatattttgt
    31381 aagtcatctc gactaccgaa gatttcaatt tctttatctt ctaaatcaat cgaacttaac
    31441 tctttatcat ctgctaaact acctttctgt ttaacattta ctttaacctt tttgctaaaa
    31501 ggctctactt taacttgtaa attcacttca ttaggttgaa tcgatacatt taatttattc
    31561 agttttttat caaaagccgt tacttctgcg acatcttttg tgtcaccatt aatcttttta
    31621 ttagttttaa aagtggcttt taaataagcg atatcattca attgttcttc tccacctgtt
    31681 actttaactg tttgtggtga aacttcttgc tttgtaattt tataaagtgg atcaatatca
    31741 ctctgactta catcaggttg aactgtcatc tttttagtta ctttgttttc aagcgtaata
    31801 tttgctaatt taggttttac agaataatga atgtcatcag ctaacccttt aacttgatac
    31861 ttctcttgat attttccagc ttttgcattt gataaatcaa tcactactct taaatcttct
    31921 ggattttcaa tttttattat ctttgattgt ggtcctgaaa tagtcacatt aactgtttca
    31981 ggcgcttttg ttaaatgcaa atctttagtg ttataaagaa tttcaacggg tacatcttga
    32041 atcgttttac tagacttttg accaagatta ccagtgttaa agatatttcc aaaaacattg
    32101 ttaacagata aaaagaaaaa caatgccaaa agaaaggcaa taaatctcaa gccccattta
    32161 ctttctagca tattatttca cacctttctt ttgaaagcgt gtgccaaacc aatgttcagc
    32221 aagcaactct tcaaaaattt cgtttgaaat gtctcgtcgt aattttccat caaatgttac
    32281 cgaaatatca ccagtttctt cagatacaat aacggtaaat gcatcagata cttctgaaat
    32341 accaaccgca gctctatgtc ttgtacccaa acttttagat atcttaggac tatcagacaa
    32401 tggcaaataa cttgctgctg ctgcaatctt agtgccttga ataatcattg caccatcatg
    32461 taaaggtgtg ttaggtataa agacattaat taaaagttct tgcgaaatat ttgaatccat
    32521 tgcaatacct gtttcaatat aatcttgaag acctgtttct ttttcaaaga caattaatgc
    32581 acctatacgt cttttagcca tatattgcac agcctttgaa accgattgaa tcaatttctc
    32641 ttcatcttta ctatacgtat tagaagtata gcgttttaaa aagctacctc taccaagttg
    32701 ttctaacgca cgtctaattt ctggttggaa tattactatt aaagctaata ccccccattg
    32761 aataacgata tcgaataatt tagatgttgc agtcaagttc aatatcatac ttatctgctg
    32821 accaataaca attactaata tccctttaag taattgtatc gctttagttc ccttaaagac
    32881 cgtgatgaga agataaagta cataccaaac tatcagtaaa tcaaggatac tcgttacaat
    32941 ttttaacgta ctgaggtttt gaaaaaagtt ggaaaaatcc ataacatctc ctccgggtaa
    33001 tatttttcca taatacccat tataccaatc atttacatca ctgtcatacg aacatatatt
    33061 taaatagaaa aaatttattt taaagattat aactactctt aatcatttta gtgaattaaa
    33121 aaaagtagtg caaaaagcaa aatatacttt atacactaca aatcatttat ttataataaa
    33181 gtttcaccga aaaatgttcc aactaatgaa accgcttgtt cagcagtatg attattactg
    33241 tcaatcaatg gatttacttc aactaaatcc attgatgtta ctgattgaga ctgatgtaat
    33301 aattccagcg caaaatgact ttctctatat gtaagtccac ctaatactct tgtacctgtg
    33361 cctggcgttt caagtggatc taaggcatca acgtcaagag ataaatgtat accatctaca
    33421 ttatgagttt ttaaataatc taatgtattt tcaattacag tctgaattcc tagtttatct
    33481 atgtcagcca tagtaaatgt tttaatattt ttatctttaa taaattgtcg ttcaccttta
    33541 tccaaatctc tcataccaat tagcacaata ttttcaggtt taatggtatt aatattgaat
    33601 tctaatagtt cctttggtcc ttcacctgtc aaaatccgaa gtggcatacc atgaatattt
    33661 ccacttggtg actcttcagg tatatttaaa tcaccatgtg catcatacca aataacacct
    33721 aaattattat aatgtttact tattgctgat actgaaccta ccgcaataga atgatctcca
    33781 ccaagaacta gaggaaatct gttattttca attgatgctg aaacttcttt atttaatttt
    33841 tgagtaacat ctataatttc atcgtagttt cttaatccat tttgttcact ttgaaatttt
    33901 tcaatgtcta cagctgatac cttaatatcc cctttgtcat taacatcaag gtctaattgc
    33961 tttagtcttg gtattaaacc tgcatatcta atcgcagttg gtcctaaatc aacacctaat
    34021 tttctttgtc caaatgttga tggtgcacca ataatatcaa ttgcttttgt ctttgtcata
    34081 agcgtccccc ctttgttata cataatttca gaataatgta tacgcttact ataatcaagt
    34141 aatagccata acataacccc ttagcattct aattctcaaa aaataaaaaa aagcacttcc
    34201 caagaatgga aagtgcaagt agtgagccat agaggattcg aacctctgac cctctgatta
    34261 aaagtcagat gctctaccaa ctgagctaat ggctctaatg gctgggctag ctggattcga
    34321 accaacgagt gacggagtca aagtccgttg ccttaccgct tggctatagc ccaatatata
    34381 gatggtggag gggggcagat tcgaactgcc gaacccgaag gagcggattt acagtccgcc
    34441 gcgtttagcc acttcgctac ccctccagct tattcagtta attaataatc aaaatggtgg
    34501 agaatgacgg gttcgaaccg ccgaccctct gcttgtaagg cagatgctct cccagctgag
    34561 ctaattctcc aatataatga ctcctacggg actcgaaccc gtgttaccgc cgtgaaaggg
    34621 cggtgtctta accgcttgac caaggagcca tggctccaca ggtaggactc gaacctacga
    34681 ccgatcggtt aacagccgat agctctacca ctgagctact gtggattaat attaatgcct
    34741 ggcaacgttc tactctagcg gaacgtaagt tcgactacca tcgacgctaa ggagcttaac
    34801 ttctgtgttc ggcatgg
//
LOCUS       DAPSKH010000029        34568 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPSKH010000029 DAPSKH010000000
VERSION     DAPSKH010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 34568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34568
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.029"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            322..3027
                     /gene="acnA"
                     /locus_tag="RPH49_001402"
     CDS             322..3027
                     /gene="acnA"
                     /locus_tag="RPH49_001402"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDY5124552.1"
                     /translation="MAANFKEQSKKHFDLNGQSYTYYDLKAVEEQGITKVSNLPYSIR
                     VLLESLLRQEDDFVITDDHIKALSQFGKDGNEGEVPFKPSRVILQDFTGVPAVVDLAS
                     LRKAMDDVGGDITKINPEVPVDLVIDHSVQVDSYANPEALERNMKLEFERNYERYQFL
                     NWATKAFDNYNAVPPATGIVHQVNLEYLASVVHVRDVDGEKTAFPDTLVGTDSHTTMI
                     NGIGVLGWGVGGIEAEAGMLGQPSYFPIPEVIGVRLVNSLPQGATATDLALRVTQELR
                     KKGVVGKFVEFFGPGVQHLPLADRATIANMAPEYGATCGFFPVDDESLKYMKLTGRSD
                     EHIALVKEYLKQNHMFFDVEKEDPNYTDVIELDLSTVEASLSGPKRPQDLIFLSDMKS
                     SFENSVTAPAGNQGHGLDKSEFDKKAEINFKDGSKATMKTGDIAIAAITSCTNTSNPY
                     VMLGAGLVAKKAVEKGLKVPEYVKTSLAPGSKVVTGYLRDAGLQPYLDDLGFNLVGYG
                     CTTCIGNSGPLLPEIEKAIADEDLLVTSVLSGNRNFEGRIHPLVKANYLASPQLVVAY
                     ALAGTVDIDLQNEPIGKGNDGEDVYLKDIWPSIKEVSDTVDSVVTPELFIEEYNNVYN
                     NNELWNEIDVTDQPLYDFDPNSTYIQNPSFFQGLSKEPGTIVPLNGLRVMGKFGDSVT
                     TDHISPAGAIGKDTPAGKYLQDHQVPIREFNSYGSRRGNHEVMVRGTFANIRIKNQLA
                     PGTEGGFTTYWPTNEVMPIFDAAMKYKEDGTGLVVLAGNDYGMGSSRDWAAKGTNLLG
                     VKTVIAQSYERIHRSNLVMMGVLPLEFKKGESADSLGLDGTEEISVNIDENVQPHDYV
                     KVTAKKHDGDLVEFDAMVRFDSLVEMDYYRHGGILQMVLRNKLAQ"
     gene            3167..4734
                     /locus_tag="RPH49_001403"
     CDS             join(3167..3842,3842..4734)
                     /locus_tag="RPH49_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611580.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDY5124553.1"
                     /translation="MKTLKGAIFMPIKPKVDIDVLLYMFQEYEKGVSFQYLIDTLQLD
                     INVNTLYPKYKYYKTHGIETLLTQKQYNRYSKELKLKVVNEYLNSNQSTQDLAIKYNI
                     RSSTQVKNWIKMYTVGKEIKNQSPKTGVYIMKARKTTFEERVTIVEYYLNHKQSYREV
                     AEHFNISYGQIYQWVQKYQAHGKNGLVDGRGKGKPKSMMTPEEQKEAEIQALKAQNRL
                     LEMENDVFKKVSSIGKRNDSKRKQITAYKTIEALKHQYPIQRLCRILGISRASYYKWV
                     HYQPSELELENEQLKREIESIYHKYNGIYGYRRIYIYIRLKLGKQVNRKRIYCLMKEL
                     NLKAVIRQKRKPYRRSTPQITSENKLNRQFDIDTPNKVWLTDVTEFKIKDGSKIYLSA
                     IYDLGAKRIVSYELGPSNNNQLVFKTFNQAIEKVENTKGILFHSDRGFQYTSKTFKHM
                     LDECGMIQSMSRVSKCIDNGPMEGVWGTIKSEIFRGNKHFKFNSVEEATKTIHDFIHF
                     FNYERITLKMADSV"
     gene            4869..5336
                     /locus_tag="RPH49_001404"
     CDS             4869..5336
                     /locus_tag="RPH49_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDY5124554.1"
                     /translation="MIYSITEIEARYAETDKMGVIYHGNYATWFEVARLDYISKLGFS
                     YADMEKQGIISPVTDLNVNYKKSIFYPEKVKVKTWVEKYSRLRSVYKYEIFNEKGELA
                     TTGSTELICIKEDTFKPIRLDRYFPDWHEAYSKVQTLNNEGKTVEIMDDIDSL"
     gene            complement(5543..5839)
                     /locus_tag="RPH49_001405"
     CDS             complement(5543..5839)
                     /locus_tag="RPH49_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HesB/YadR/YfhF family protein"
                     /protein_id="HDY5124555.1"
                     /translation="MQIELTDAAVTWFKNELELPENNKVLVFFVRYGGEFQLKQGFSP
                     AFTVEPKEDVDIGYEQQYDDLNVVVAEKDLWYFEDDHIIVNVVDHEDEISYSTK"
     gene            complement(6214..6822)
                     /gene="plsY"
                     /locus_tag="RPH49_001406"
     CDS             complement(6214..6822)
                     /gene="plsY"
                     /locus_tag="RPH49_001406"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDY5124556.1"
                     /translation="MMIIVMLLLSYLIGAFPSGFVIGKLFFKKDIRQFGSGNTGATNS
                     FRVLGRPAGFLVTFLDIFKGFITVFFPLWLPVHADGPISTFFTNGLIVGLCAILGHVY
                     PVYLKFQGGKAVATSAGVVLGVNPILLLILAIIFFVVLKIFKYVSLASIVAAICCVIG
                     SLIIQDYILLVVSFLVSIILIIRHRSNIARIFRGEEPKIKWM"
     gene            7028..9019
                     /gene="parE"
                     /locus_tag="RPH49_001407"
     CDS             7028..9019
                     /gene="parE"
                     /locus_tag="RPH49_001407"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDY5124557.1"
                     /translation="MNKQNNYSDDSIQVLEGLEAVRKRPGMYIGSTDKRGLHHLVYEI
                     VDNSVDEVLNGYGNEIDVTINKDGSISIEDNGRGMPTGIHKSGKPTVEVIFTVLHAGG
                     KFGQGGYKTSGGLHGVGASVVNALSEWLEVEIHRDGNIYHQSFKNGGSPSSGLVKKGK
                     TKKTGTKVTFKPDDTIFKASTSFNFDVLSERLQESAFLLKNLKITLNDLRSGKERQEH
                     YHYEEGIKEFVSYVNEGKEVLHDVATFSGEANGIEVDVAFQYNDQYSESILSFVNNVR
                     TKDGGTHEVGFKTAMTRVFNDYARRINELKTKDKNLDGNDIREGLTAVVSVRIPEELL
                     QFEGQTKSKLGTSEARSAVDSVVADKLPFYLEEKGQLSKSLVKKAIKAQQAREAARKA
                     REDARSGKKNKRKDTLLSGKLTPAQSKNTEKNELYLVEGDSAGGSAKLGRDRKFQAIL
                     PLRGKVINTEKARLEDIFKNEEINTIIHTIGAGVGTDFKIEDSNYNRVIIMTDADTDG
                     AHIQVLLLTFFFKYMKPLVQAGRVFIALPPLYKLEKGKGKTKRVEYAWTDEELNKLQK
                     ELGKGFTLQRYKGLGEMNPEQLWETTMNPETRTLIRVQVEDEVRSSKRVTTLMGDKVQ
                     PRREWIEKHVEFGMQEDQSILDNSEVQVLENDQFDEEEI"
     gene            9019..11421
                     /gene="parC"
                     /locus_tag="RPH49_001408"
     CDS             9019..11421
                     /gene="parC"
                     /locus_tag="RPH49_001408"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDY5124558.1"
                     /translation="MSEIIQDLSLEDVLGDRFGRYSKYIIQERALPDVRDGLKPVQRR
                     ILYAMYSSGNTHDKNFRKSAKTVGDVIGQYHPHGDFSVYEAMVRLSQDWKLRHVLIEM
                     HGNNGSIDNDPPAAMRYTEAKLSLLAEELLRDINKETVSFIPNYDDTTLEPMVLPSRF
                     PNLLVNGSTGISAGYATDIPPHNLAEVIQATLKYIDNPDITVNQLMKYIKGPDFPTGG
                     IIQGIDGIKKAYESGKGRIIVRSKVEEETLRNGRKQLIITEIPYEVNKSSLVKRIDEL
                     RADKKVDGIVEVRDETDRTGLRIAIELKKDVNSESIKNYLYKNSDLQISYNFNMVAIS
                     DGRPKLMGIRQIIDSYLNHQIEVVANRTKFELDNAEKRMHIVEGLIKALSILDKVIEL
                     IRSSKNKRDAKGNLIEVFEFTEEQAEAIVMLQLYRLTNTDIVALEGEHKELEALIKQL
                     RHILDNHDALLNVIKEELNEIKKKFKSERLSLIEAEIEEIKIDKEVMVPSEEVILSMT
                     RHGYIKRTSIRSFNASGVEDIGLKDGDSLLKHQEVNTQDTVLVFTNKGRYLFIPVHKL
                     ADIRWKELGQHVSQIVPIEEDEVVINVFNEKDFNTDAFYVFATQNGMIKKSTVPLFKT
                     TRFNKPLIATKVKENDDLISVMRFERDQLITVITNKGMSLTYNTSELSDTGLRAAGVK
                     SINLKAEDFVVMTEGVSENDTILMATQRGSLKRISFKILQVAKRAQRGITLLKELKKN
                     PHRIVAAHVVTGEHSQYTLYSKSNEEHGLINDIHKSEQYTNGSFIVDTDDFGEVIDMY
                     IS"
     gene            11671..13131
                     /locus_tag="RPH49_001409"
     CDS             11671..13131
                     /locus_tag="RPH49_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDY5124559.1"
                     /translation="MKDFDSLIPGWFKEFVHVGTDLIWSQYLIGLLLTAGFFFTISSK
                     FVQLRMLPEMFRALVERPETLEDGKKGISPFQAFAISAGSRVGTGNIAGVATAIVLGG
                     PGAVFWMWVIAFIGAASAFIEATLAQVYKVHDKDGGFRGGPAYYITKGLNQKWLGIVF
                     AILITITFAFVFNTVQSNTIAESLNTQYNISPVITGIILAIVTAIIIFGGVRSIATLS
                     SLIVPIMAIIYIGMVLVILLFNLDQIVPMIGTIIKSAFGIEQVTGGAVGAAVLQGIKR
                     GLFSNEAGMGSAPNAAATAAVPHPVKQGLIQSLGVFFDTMLVCTATAIMILLYSGLKF
                     GDNAPQGVAVTQSALNEHLGSAGGIFLTIAVTLFAFSSVVGNYYYGQSNIEFLSTNRV
                     ILFIFRCLVVVLVFVGAVVKTETVWNTADLFMGLMAIVNIISIIGLSNVAFALMKDYQ
                     KQKKEGKNPVFKPENLEINLFGISAWGANKYKNSDK"
     gene            13631..14482
                     /locus_tag="RPH49_001410"
     CDS             13631..14482
                     /locus_tag="RPH49_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HDY5124560.1"
                     /translation="MGEYIVTKTLNNNVVVCTNNDQEVILIGKGIGFNKKEGMTLNDQ
                     TITIEKIYKLESEQQKAHYKSLVEIADDNVLQVIIDSLNFISNTAMNVDSKQLVVSLT
                     DHIIFAYKRLKQNQVISNPFVMETMQLYSDAYHIAKQVIDQLNAALDVHFPEDEIGFI
                     ALHIASNTEDLSMHEMTLINNVIKKGIDIIESDLVTTVDKESLQYQRFIRHVQFLIRR
                     LRRKEYIHAQDDFVSMIKNHYPICYNTAYKILTMIQKQFDVTISESEIIYLTLHIHHF
                     EERINHS"
     gene            14457..14624
                     /locus_tag="RPH49_001411"
     CDS             14457..14624
                     /locus_tag="RPH49_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124561.1"
                     /translation="MKKGLIIPKLSALYGRFVTVKGICMVSLMLVILHKWTVFIQHLM
                     NILSGGESIIE"
     gene            14617..15825
                     /locus_tag="RPH49_001412"
     CDS             14617..15825
                     /locus_tag="RPH49_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDY5124562.1"
                     /translation="MNENEKNIRKNFLKFTESRYMKFVGGNDLVFSLIALVLLGIVIF
                     IFEKVSYVFDPFIIVFKTIAAPIIVSLILFYLFNPIVNMMERYRIPRVAGISIIYLAV
                     VGVITLIVNLLIPIIGSQVDSLVKNSPQYLEKLINSIDKIANNTFFSSYYSQINDWLN
                     SLPKKIPSMLSEFTDGFGSKIATFAETIANIGVVIVTTPFVLFFMLKDGHHFKEFSTN
                     IMPPKFRKDFHDLLEKMSVQVGSYIQGQIIVSFCIGILLFIGYSVIGLKYSLVLASIA
                     AVTSVVPYLGPTIAISPAIVIAAITSPWMLLKLAVVWTLVQFVEGHFISPNIMGKTLK
                     IHPLTIIFILLCAGKLLGIVGVILGIPGYAILKVLVTHLFQLFKRRYNRFYGNDVGEY
                     DIKESNKIVE"
     gene            16306..18828
                     /gene="mprF"
                     /locus_tag="RPH49_001413"
     CDS             16306..18828
                     /gene="mprF"
                     /locus_tag="RPH49_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDY5124563.1"
                     /translation="MNQEVKNKVFSILKITFATALFIFVVITLYRELSGINFKDTLVE
                     FSKINRMSLVLLFIGGGASLVILSMYDVILSRALKMDISLGKVLRVSYIINALNAIVG
                     FGGFIGAGVRAMVYKNYTHDKKKLVHFISLILISMLTGLSLLSLLIVFHVFDASLILD
                     KITWVRWVLYVVSFFLPLFIIYSMVRPPDKNNRFVGLYCTLVSCVEWLAAAVVLYFCG
                     VIVDAHVSFMSFIAIFIIAALSGLVSFIPGGFGAFDLVVLLGFKTLGVPEEKVLLMLL
                     LYRFAYYFVPVIIALILSSFEFGTSAKKYIEGSKYFIPAKDVTSFLMSYQKDIIAKIP
                     SLSLAILVFFTSMIFFVNNLTIVYDALYDGNHLTYYILLAIHTSACLLLLLNVVGIYK
                     QSRRAIIFAMISILLITVATFFTYASYILITWLAIIFVLLIVAFRRARRLKRPVRMRN
                     IVAMLLFSLFILYVNHIFIAGTLYALDIYTIEMHTSVLRYYFWLTILIIAIIIGMIAW
                     LFDYQFSKVRISSKIEDCEEIINQYGGNYLSHLIYSGDKQFFTNENKTAFLMYRYKAS
                     SLVVLGDPLGDENAFDELLEAFYNYAEYLGYDVIFYQVTDQHMPLYHNFGNQFFKLGE
                     EAIIDLTQFSISGKKRRGFRATLNKFDELNISFEIIEPPFSTEFINELQHVSDLWLDN
                     RQEMHFSVGQFNEEYLSKAPIGVMRNEENEVIAFCSLMPTYFNDAISVDLIRWLPELD
                     LPLMDGLYLHMLLWSKEQGYTKFNMGMATLSNVGQLHYSYLRERLAGRVFEHFNGLYR
                     FQGLRRYKSKYNPNWEPRFLVYRKDNSLWESLSKVMRVIRHK"
     gene            complement(19031..19540)
                     /gene="msrA"
                     /locus_tag="RPH49_001414"
     CDS             complement(19031..19540)
                     /gene="msrA"
                     /locus_tag="RPH49_001414"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDY5124564.1"
                     /translation="MNINTAYFAGGCFWCMTKPFDTFDGIEKVTSGYMGGHIENPTYE
                     QVKSGTSGHLETVEIQYDVALFSYNKLLEIFFSVIDPLDTGGQYQDRGPQYQTAIFYT
                     NDHQKELAETYIEQLKNTINADKAIATKILPASQFYKAEDYHQDFYKKNPERYAEEQK
                     IRQEYKNKQ"
     gene            19677..20660
                     /locus_tag="RPH49_001415"
     CDS             19677..20660
                     /locus_tag="RPH49_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDY5124565.1"
                     /translation="MDKETNDNEYRRQSEHRTSAPKRKKKKKIRKLPIILLIVVILLI
                     ALVVYIVHSYNSGVEYAKKHAKDVKVHQFNGPVKNDGKISILVLGADKAQGGQSRTDS
                     IMVVQYDFINKKMKMMSVMRDIYADIPGYGKHKINSAYALGGPELLRKTLDKNLGINP
                     EYYAVVDFTGFEKMIDELMPEGVPINVEKDMSKNIGVSLKKGNHRLNGKELLGYARFR
                     HDPEGDFGRVRRQQQVMQTLKKEMVNFRTVVKLPKVAGILRGYVNTNIPDSGIFQTGL
                     SFGIRGEKDVKSLTVPIKNSYEDVNTNTDGSALQINKNTNKQAIKDFLDED"
     gene            complement(20748..20933)
                     /locus_tag="RPH49_001416"
     CDS             complement(20748..20933)
                     /locus_tag="RPH49_001416"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDY5124566.1"
                     /translation="MPIVNVKLLEGRSDEQLKNLVSEVTDAVEKTTGANRQAIHVVIE
                     EMKPNHYGVAGVRKSDQ"
     gene            21081..22343
                     /locus_tag="RPH49_001417"
     CDS             21081..22343
                     /locus_tag="RPH49_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDY5124567.1"
                     /translation="MYNYHLLEDRDVLCIDQKSFFASVSCIEKGLDPLETKLAVVADT
                     KRQGSVVLAATPKLKELGIKTGSRLFEIPHRNDIYIINPSMRKYLNVSVAISKIALRY
                     IPPEDLHQYSIDEFFMDVTDSYHRFSSTVHAFCERLKREIYEETGIYCTVGIGSNMLL
                     SKIAMDVEAKHSQNGIAEWRYQDVPTKLWPIQPLRDFWGINRRTEAKLNKRGIFTIGD
                     LAKYPYKFLKKEFGILGVDMHLHANGIDQSKVREKHKISNPSICKSQILMRDYHFDEA
                     KVVMQELIEDVASRVRARKKVARTIHFAFGYSDEGGVHKQYTLKDPTNLEKDIYKVVM
                     HFADKLCNKQALYRTLSISLSQFINEDERQLSLFEDEYQRKRDECLAKTIDQLHLKYG
                     KGIVSKAVSFTEAGTKHGRLGLMAGHKM"
     gene            complement(22480..23571)
                     /locus_tag="RPH49_001418"
     CDS             complement(22480..23571)
                     /locus_tag="RPH49_001418"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDY5124568.1"
                     /translation="MTTVLFVGLGLIGGSLASNIKYHKPNTNIIAYDADTSQLDKAKS
                     IGIINEKCLNYSEAIKKADVIIYATPVAITNKYLSKLIDMPTKPGVIVSDTGSTKAMI
                     QQHECNLLKHNIHLVSGHPMAGSHKSGVLNAKKHLFENAYYILVYNEARNEQAANTLK
                     ELLSPTLAKFIVTTAEEHDYVTSVVSHLPHIVASSLVHVSQKNGQEHHLVNKLAAGGF
                     RDITRIASSNAQMWKDITLSNKTYILEMIRQLKSQFQDLERLIESNDSEKLLSFFAEA
                     KSYRDALPAKQLGGLNTAYDLYVDIPDESGMISKVTYILSLHNISISNLRILEVREDI
                     YGALKISFKNPTDRERGMQALSDFDCYIQ"
     gene            23736..24767
                     /locus_tag="RPH49_001419"
     CDS             23736..24767
                     /locus_tag="RPH49_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDY5124569.1"
                     /translation="MEPILEMIKTLTGINSPSGDTEEAIQFVEKYAKDLGYQTTLTNK
                     GALLITVPGKNDEVQRCITAHVDTLGAMVKEIKEDGRLAIELIGGFTYNAIEGEYCQI
                     KTDAGQIYTGTICLHETSVHVYKNNHEITRDQKHMEIRVDEVTTSEEDTKSLGISVGD
                     FVSFDPRTVITSSGFIKSRHLDDKASVAMILQLLKKLKEEQIILPHTTQFYISNNEEI
                     GYGANASIDSKIKEYIALDMGALGDGQASDEYTVSICAKDASGPYHKQLKSHLVNLCK
                     INNIPYKVDIYPYYGSDASAALHAGADIRHGLFGAGIESSHAMERTHIDSIKATEKLL
                     YAYCLSPIE"
     gene            25259..26665
                     /locus_tag="RPH49_001420"
     CDS             25259..26665
                     /locus_tag="RPH49_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDY5124570.1"
                     /translation="MDIFYKKIKANVTPEVLAQLHSKKIILESTNQQQTKGRYSVVIF
                     DIYGTLTLDNDVLSVSTLKESYQIIERPYHYLTTKINEDYHNIQDEQLKSLPFISGYV
                     GTCSFDLVRHEFPKLQSIQLEDHKQHDVRLYMVEQVYVFDHYKDELYIIATNQFSNST
                     KSDLENRVNKSIEDLTKIQPFMPTQDFDFKTKEIQSNISEERFIEMIQYFKEKITEGD
                     MFQVVPSRIYKYAHHASQHLNQLSFQLYQNLKRQNPSPYMYYLNIDKPYIVGSSPESF
                     VSVKDQIVTTNPIAGTIQRGETTQIDNENMKQLLNDPKECSEHRMLVDLGRNDIHRVS
                     KIGTSKITKLMVIEKYEHVMHIVSEITGKINQNLSPMTVIANLLPTGTVSGAPKLRAI
                     ERIYEQYPHKRGVYSGGVGYINCNHNLDFALAIRTMMIDEQYINVEAGCGVVYDSIPE
                     KELNETKLKAKSLLEVSP"
     gene            26662..27228
                     /locus_tag="RPH49_001421"
     CDS             26662..27228
                     /locus_tag="RPH49_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDY5124571.1"
                     /translation="MILVVDNYDSFTYNLVDIVAQHTDVIVQYPDDDNVLNQSVDAVI
                     ISPGPGHPLDDQQLMKIISTYQHKPILGICLGAQALTCYYGGEVIKGDKVMHGKVDTI
                     SITSNTHKVLYQDVPEQFSIMRYHSLISNPDNFPEELKITGRTKDCIQSFEHKERPHY
                     GIQYHPESFATDYGVKIITNFINLVKEG"
     gene            27234..28232
                     /gene="trpD"
                     /locus_tag="RPH49_001422"
     CDS             27234..28232
                     /gene="trpD"
                     /locus_tag="RPH49_001422"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HDY5124572.1"
                     /translation="MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSE
                     REIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGV
                     KVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQ
                     PVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGA
                     NGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAITLNI
                     LNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE"
     gene            28234..29019
                     /gene="trpC"
                     /locus_tag="RPH49_001423"
     CDS             28234..29019
                     /gene="trpC"
                     /locus_tag="RPH49_001423"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HDY5124573.1"
                     /translation="MTILSEIVKYKQSLLQNGYYQDKLNTLKSVKIQNKKSFINAIEK
                     EPKLAIIAEIKSKSPTVNDLPERDLSQQISDYDQYGANAVSILTDEKYFDGSFERLQA
                     LTTKTTLPVLCKDFIIDPLQIDVAKQAGASMILLIVNILSDKQLKDLYNYAISQNLEV
                     LVEVHDRHELERAYKVNAKLIGVNNRDLKRFVTNVEHTNTILENKKPNHHYISESGIH
                     DASDVRKILHSGIDGLLIGEALMRCDNISEFLPQLKMQKVKSR"
     gene            29016..29648
                     /locus_tag="RPH49_001424"
     CDS             29016..29648
                     /locus_tag="RPH49_001424"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HDY5124574.1"
                     /translation="MKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKK
                     LASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKI
                     TKALAADENIIQNINKYKEFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGG
                     INSENIQKVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRENE"
     gene            29641..30855
                     /gene="trpB"
                     /locus_tag="RPH49_001425"
     CDS             29641..30855
                     /gene="trpB"
                     /locus_tag="RPH49_001425"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDY5124575.1"
                     /translation="MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKAD
                     PEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQA
                     LLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
                     AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKE
                     IKSQILKKEGRLPDAIVACIGGGSNAIGTFYPFIKDDVALYGVEAAGQGEDTDKHALA
                     IGKGSPGVLHGTKMYLIQDEGGQVQLAHSISAGLDYPGIGPEHSYYHDIGRVTFENAS
                     DTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETI
                     RQYMAERGLAND"
     gene            30848..31576
                     /locus_tag="RPH49_001426"
     CDS             30848..31576
                     /locus_tag="RPH49_001426"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDY5124576.1"
                     /translation="MTKLFIPYIMGNKDLIENATLLSENGADIIEIGVPFSDPVADGP
                     VIMEAGQQAIKQGITIDYIFNQLEKHGDQIKCNYVLMTYYNIICHYGEQAFFEKCRDT
                     GVYGLIIPDLPYELSQRLKEQFSHYGVKIISLVAMTTDDKRMKDIVSHAEGFIYTVTM
                     NATTGQNGAFHPELKRKIESIKAIANVPVVAGFGIRTPQHVADIKEVADGIVIGSEIV
                     KRFKSNTREEIIKYLQSIQQTLNN"
     gene            31898..33160
                     /gene="femA"
                     /locus_tag="RPH49_001427"
     CDS             31898..33160
                     /gene="femA"
                     /locus_tag="RPH49_001427"
                     /EC_number="2.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine glycyltransferase FemA"
                     /protein_id="HDY5124577.1"
                     /translation="MKFTNLTAKEFGAFTDSMPYSHFTQTVGHYELKLAEGYETHLVG
                     IKNNNNEVIAACLLTAVPVMKVFKYFYSNRGPVIDYENQELVHFFFNELSKYVKKHRC
                     LYLHIDPYLPYQYLNHDGEITGNAGNDWFFDKMSNLGFEHTGFHKGFDPVLQIRYHSV
                     LDLKDKTADDIIKNMDGLRKRNTKKVKKNGVKVRYLSEEELPIFRSFMEDTSESKAFA
                     DRDDKFYYNRLKYYKDRVLVPLAYINFDEYIKELNEERDILNKDLNKALKDIEKRPEN
                     KKAHNKRDNLQQQLDANEQKIEEGKRLQEEHGNELPISAGFFFINPFEVVYYAGGTSN
                     AFRHFAGSYAVQWEMINYALNHGIDRYNFYGVSGKFTEDAEDAGVVKFKKGYNAEIIE
                     YVGDFIKPINKPVYAAYTALKKVKDRIF"
     gene            33179..34438
                     /gene="femB"
                     /locus_tag="RPH49_001428"
     CDS             33179..34438
                     /gene="femB"
                     /locus_tag="RPH49_001428"
                     /EC_number="2.3.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine glycyltransferase FemB"
                     /protein_id="HDY5124578.1"
                     /translation="MKFTELTVTEFDNFVQNPSLESHYFQVKENIVTRENDGFEVVLL
                     GIKDDNNKVIAASLFSKIPTMGSYVYYSNRGPVMDFSDLGLVDYYLKELDKYLQQHQC
                     LYVKLDPYWLYHLYDKDIVPFEGREKNDALVNLFKSHGYEHHGFTTEYDTSSQVRWLG
                     VLNLEGKTPETLKKTFDSQRKRNINKAINYGVKVRFLERDEFNLFLDLYRETEERAGF
                     VSKTDDYFYNFIDTYGDKVLVPLAYIDLDEYVLKLQQELNDKENRRDQMMAKENKSDK
                     QMKKIAELDKQIDHDQHELLNASELSKTDGPILNLASGVYFANAYEVNYFSGGSSEKY
                     NQFMGPYMMHWFMINYCFDNGYDRYNFYGLSGDFTENSEDYGVYRFKRGFNVQIEELI
                     GDFYKPIHKVKYWLFTTLDKLRKKLKK"
BASE COUNT        12240 a         4899 c         6318 g        11111 t
ORIGIN      
        1 tcatttctgt cccactccca tcaaaagaat gacattgaaa agaaatatta aagtttggcg
       61 ctataatttt ctttctgctc aatgaaataa tacgtttgaa aattgaattg aatcattcgc
      121 gaaattgata attattctca attaataaaa aatacttatt acaccttact tgtatgataa
      181 gttttgctta tatactctga ttaaaaagtc aaaacctaaa ttaagcgttt tctaagcatg
      241 atgagttgtt tatcaataaa tataataata caatttaatc aaggcatata aatataaaaa
      301 tgtatcaagg gggatcatta aatggctgca aattttaaag agcaatcaaa aaaacatttt
      361 gacttgaatg gccaaagtta tacttactat gatttaaaag ctgtagaaga gcaaggtatt
      421 actaaagttt ccaatttacc ttattcaatt cgtgttttgt tagaatcttt acttcgtcaa
      481 gaagatgatt ttgtaattac agacgatcat attaaagctt taagtcagtt tggaaaagat
      541 ggaaatgaag gcgaggtacc atttaaacct tctcgtgtta ttttacaaga tttcacaggt
      601 gtaccagccg tagttgattt agcttcttta cgtaaagcaa tggatgacgt tgggggagat
      661 attactaaaa ttaatccaga agtaccggtg gatttagtta ttgaccactc agttcaagtg
      721 gatagctatg caaatccaga agctcttgaa cgtaatatga aattagaatt tgaacgtaac
      781 tatgaacgtt atcagttttt aaattgggca acgaaagcat ttgataatta caatgcagtt
      841 cctcctgcaa ctggaatagt tcaccaagtt aacttagaat atttagcaag tgttgtacat
      901 gttcgtgatg tagatggtga aaaaactgca tttccagata cattagttgg tactgattca
      961 catacaacaa tgataaatgg tattggcgta ctaggatggg gtgttggtgg tattgaagct
     1021 gaagctggaa tgcttggaca accttcttat ttcccaattc cagaggttat tggtgtacga
     1081 ctagtaaatt cattaccaca aggcgcaaca gcaactgatt tagcgttaag agtaactcaa
     1141 gagctacgta aaaaaggtgt tgttggtaaa tttgtggagt tctttggtcc aggtgtacaa
     1201 catttaccac tagcagaccg tgctacaatt gcaaacatgg caccagagta tggagcaact
     1261 tgcggattct tcccagttga tgatgaatct cttaaatata tgaagttaac tggtagatca
     1321 gacgaacata tcgcgctagt aaaagaatat ttgaaacaaa accatatgtt ctttgatgtt
     1381 gagaaagaag atcctaatta tacagatgtt atcgaattgg atttatcaac agttgaagca
     1441 tcgctttcag gaccaaaacg tcctcaagat ttaattttct taagtgatat gaaatcatca
     1501 tttgaaaatt ctgtaacagc tccagcaggc aaccaaggac acggtttaga taaaagtgaa
     1561 tttgataaga aagctgaaat taactttaaa gatggatcaa aagctacaat gaaaacaggt
     1621 gatattgcaa tagcagcaat tacatcatgt acaaatacat ctaaccctta tgtaatgtta
     1681 ggtgcaggtt tagttgctaa aaaagcagtt gaaaaaggct tgaaagttcc tgaatacgtt
     1741 aaaacttctc tagcaccagg atcaaaagtt gttaccggat atttaagaga tgctggctta
     1801 caaccttatt tagatgattt aggcttcaac ttggttggtt atggatgtac aacttgtatc
     1861 ggtaattcag gtcctttatt accagaaatt gaaaaagcga ttgctgatga ggacctatta
     1921 gtgacatctg tattatctgg taaccgtaac tttgaaggtc gtatccatcc tcttgttaaa
     1981 gccaattacc tagcttcacc acagttagtt gttgcttatg cattagctgg aacggttgat
     2041 attgatttac agaatgaacc tattggtaaa ggtaatgacg gtgaagatgt atatttgaaa
     2101 gatatttggc catcaattaa agaagtttca gataccgttg atagtgttgt aacacctgaa
     2161 ttatttattg aagaatataa taacgtatac aataacaacg aattatggaa tgagattgat
     2221 gtaactgatc aacctctata tgactttgat cctaattcaa catacattca aaatccatca
     2281 ttcttccaag gattatctaa agaaccgggt acgattgttc cattaaatgg tttacgtgtt
     2341 atgggtaaat tcggtgattc tgtgacaact gaccacatct ctccagcagg tgcaattggt
     2401 aaagatacgc cagctggtaa atatttacaa gatcaccaag tgcctattcg tgaatttaat
     2461 tcttatggtt caagacgtgg taatcacgaa gtaatggttc gaggtacgtt tgctaatata
     2521 cgtattaaaa accaattagc gccaggcact gaaggtggtt ttacaactta ttggccaaca
     2581 aatgaagtaa tgcctatctt tgatgctgca atgaaatata aagaagatgg tacaggttta
     2641 gttgtattag ccggtaacga ttatggtatg ggttcatctc gtgactgggc agcaaaaggt
     2701 acaaacttat taggtgttaa aacagttatt gcacaaagtt atgaacgtat ccatcgttca
     2761 aatttagtta tgatgggtgt attaccatta gagtttaaaa aaggtgaatc agctgattct
     2821 cttggtctag atggtacaga agaaatttct gttaatattg atgaaaatgt tcaaccacat
     2881 gactacgtca aagttactgc taagaagcat gatggtgatt tggtagaatt tgacgctatg
     2941 gttcgttttg actcacttgt tgaaatggat tactatcgtc acggtggtat tttacaaatg
     3001 gttttaagaa ataaattagc gcaataaaaa tagatatcac agcaaaattt taatcggtat
     3061 ttgaggcact ttgatagtgc tcaaaaatac ttctataaac tttatgatat aataggtcgg
     3121 ttcaaaacct ttgtgaaatg ctcccttcaa agtagacatt gaaaaaatga aaactttgaa
     3181 gggagctata tttatgccaa taaaacctaa agtagacata gatgtactgc tatatatgtt
     3241 tcaagaatat gaaaaaggcg tgtcgtttca atacttaatc gatacattac aattagatat
     3301 taatgtcaat actttgtatc ctaagtataa atattataaa acccatggta ttgaaacact
     3361 acttacacaa aaacaataca atcgctattc aaaggaacta aaattaaaag ttgtaaatga
     3421 atatttgaat tcaaatcaat caacacaaga tctcgccatt aaatacaata ttcgtagttc
     3481 gacacaagtc aaaaattgga taaaaatgta tactgtagga aaagagatta agaatcaatc
     3541 tccgaaaact ggggtgtata tcatgaaagc aagaaaaacc acatttgaag aacgtgtcac
     3601 aattgttgaa tattacttga atcataaaca atcttataga gaagttgcag aacactttaa
     3661 tatctcatac ggtcaaattt accagtgggt ccaaaagtat caagcccatg gtaaaaatgg
     3721 gttagtagat ggcaggggca aaggaaaacc caaatctatg atgacgccag aagaacaaaa
     3781 ggaagctgaa attcaagcat taaaagcaca aaatcgatta ttagaaatgg aaaatgacgt
     3841 tttaaaaaag tttcaagcat tggaaagaga aatgattcaa agagaaaaca aatcacggca
     3901 tacaaaacga tcgaagcgtt aaagcatcaa taccctatcc aacgcttgtg tcgtatttta
     3961 ggcatttcta gagcgagtta ttataagtgg gtacattatc aaccgagtga acttgaatta
     4021 gagaatgaac agcttaagcg agaaatagaa tcaatctatc ataagtataa tggtatttat
     4081 ggctatcgtc gcatttatat ctatattcga ttaaaactag gtaaacaagt aaaccgaaag
     4141 cgaatttatt gtttgatgaa agaacttaat ttaaaagcgg taatacgtca aaagcgaaaa
     4201 ccttatcgac gttcaacgcc acaaatcaca tcagaaaata agcttaatcg acaatttgac
     4261 attgatacgc caaataaagt ttggttaaca gatgtaacag aatttaaaat caaagatggt
     4321 agtaagatat atttgagtgc catttatgac ttaggtgcta aacgtattgt tagttatgag
     4381 ctaggccctt ctaacaataa tcaattagta tttaaaacat tcaatcaagc gatagaaaaa
     4441 gtagaaaata ccaaaggtat tttatttcat agtgaccgag gttttcaata cacatcgaaa
     4501 acatttaaac atatgttgga tgaatgtggc atgattcaaa gtatgtcacg tgttagcaaa
     4561 tgtatcgata atggtcctat ggaaggtgtg tggggtacaa taaaaagtga aatttttaga
     4621 ggaaataagc actttaaatt taatagtgta gaagaagcta caaaaacaat tcatgatttt
     4681 atccatttct ttaattatga aagaattaca ttaaaaatgg ctgattctgt ataacaacaa
     4741 aaccaaccat taattttaat tatttaattg tctactagac tgggtgcagt tcattgtgtt
     4801 cttggccggc ctcttcttgt attttatgtt agaatgagat ataaagttaa actgaaagaa
     4861 ggcttaaaat gatatatagt attacagaaa tagaagcgcg ttatgctgaa actgataaga
     4921 tgggtgtaat ttatcacggg aattatgcaa cttggtttga agttgcgcgg ttggattata
     4981 tatcgaagtt aggttttagt tatgctgata tggaaaaaca aggaatcatt tcacccgtga
     5041 ctgacctcaa tgtcaattat aaaaagtcta ttttttatcc agaaaaagtt aaagttaaaa
     5101 cttgggttga aaaatattcg agattacgtt cagtgtataa atatgagatt tttaatgaaa
     5161 aaggtgaact tgcaactaca ggttccacag aattgatttg cattaaagaa gatactttta
     5221 agcctatacg gttggatcgt tatttcccag attggcatga agcctatagt aaagtgcaaa
     5281 cgctcaataa tgaagggaaa acagtagaga taatggatga tattgattct ttataagtta
     5341 ctataaatgt ttggagaggc aatattaaca attaatctat gttaaatagt caatacgtta
     5401 gcattaacgc aattagcgtg aagataagct aatatatagc aaaaacgaac ttgttcatac
     5461 aacatcagat gtgataaacc aaagtgcaac ttccgaggtt cagtacacat cagaatgtgt
     5521 aaacaagttc gttttaattt agttattttg tggaataaga aatttcatct tcgtgatcaa
     5581 ctacatttac aataatgtgg tcatcttcaa agtaccacaa atctttttcc gctacgacaa
     5641 catttaaatc gtcatattgt tgttcatagc caatatcaac atcttccttt ggttcaactg
     5701 taaaagcagg actaaatcct tgcttgagtt ggaattcgcc accatatctt acaaaaaaca
     5761 cgagcacttt attattttca ggtaactcaa gttcattttt aaaccaagtt actgctgcat
     5821 cagtaagttc tatttgcata acaatgacct cctatattta ttacagaatg gtagtgggcc
     5881 aactcgtatt gtttgtggaa tttcttttcg aaattctctg tgttggagcc caccccaacc
     5941 tgcacattat tgtaagctga atttccataa gcttctatgt tgggaccccc gaccagaatt
     6001 gaaaaaacct agttataagc gcatttcgtt ctgtcaactt cagctaatat aacattgtgg
     6061 agcctatgac attgatttat gtctcggtct caaatgttct tgtaaaaaac taagtatagt
     6121 tggattttaa gttaaaaaaa ttgtttttgc aaaaataaaa taatccatca actgcaaaaa
     6181 aatatgcaat gatggactaa tgtcaaaaaa ttgttacatc cattttattt taggttcttc
     6241 gcctctaaaa atccttgcga tattagagcg atgtctaatt atcaatatga ttgaaactaa
     6301 gaaactaacg actaataaaa tatagtcttg aatgataagc gagccaatca cacagcaaat
     6361 tgctgcaacg atacttgcta aagaaacata tttaaaaatc ttcaatacaa caaagaagat
     6421 aattgcaagt attagtaaaa gtatcggatt gactcccaag acgacacctg cactagttgc
     6481 aacagctttg ccaccttgga attttaaata aacaggataa acatgtccaa gtatagcgca
     6541 taagccaaca attaaaccat ttgtaaaaaa agtactaata gggccatctg cgtgaactgg
     6601 taaccataaa gggaagaaaa cagttatgaa ccctttgaaa atatctagaa atgttaccaa
     6661 gaatcctgca ggacgaccta atactctaaa gctattagta gcgccagtat taccactacc
     6721 aaattgtcta atatcttttt tgaaaaataa ttttccaatt acgaatccac ttgggaaagc
     6781 gccgataaga taacttagta gtaacatgac gattatcatc ataaatatta cacatccttt
     6841 aatatcttag gactatttta tcatattcgt ttaaattacg gctaaaattt ttaaaaacgg
     6901 ggattaatat atggaattaa gctatgaaag ttaattgata cttgcatttt acgctgattt
     6961 atataagaat aactattgta tagttttaaa aacgaacgta cgtttgcagg aggcgaaatc
     7021 attggcaatg aataaacaaa ataattattc agatgattca atacaggttt tagaggggtt
     7081 agaagcagtt cgtaaaagac ctggtatgta tattggatca actgataaac ggggattaca
     7141 tcatctagta tatgaaattg tcgataactc cgtcgatgaa gtattgaatg gttacggtaa
     7201 cgaaatagat gtaacaatta ataaagatgg tagtatttct atagaagata atggacgtgg
     7261 tatgccaaca ggtatacata aatcaggtaa accgacagtc gaagttatct ttactgtttt
     7321 acatgcagga ggtaaatttg gacaaggcgg ctataaaact tcaggtggtc ttcacggtgt
     7381 tggtgcttca gttgtaaatg cattgagtga atggcttgaa gttgaaatcc atcgagatgg
     7441 taatatatat catcaaagtt ttaaaaacgg tggttcgcca tcttctggtt tagtgaaaaa
     7501 aggtaaaact aagaaaacag gtaccaaagt aacatttaaa cctgatgaca caatttttaa
     7561 agcatctaca tcatttaatt ttgatgtttt aagcgaacga ctacaagagt ctgcgttctt
     7621 attgaaaaat ttaaaaataa cgcttaatga tttacgcagt ggtaaagagc gtcaagagca
     7681 ttaccattat gaagaaggaa tcaaagagtt tgttagttat gtcaatgaag gaaaagaagt
     7741 tttgcatgac gtggctacat tttcaggtga agcaaatggt atagaggtag acgtagcttt
     7801 ccaatataat gatcaatatt cagaaagtat tttaagtttt gtaaataatg tacgtactaa
     7861 agatggtggt acacatgaag ttggttttaa aacagcaatg acacgtgtat ttaatgatta
     7921 tgcacgtcgt attaatgaac ttaaaacaaa agataaaaac ttagatggta atgatattcg
     7981 tgaaggttta acagctgttg tgtctgtacg tattccagaa gaattattac aatttgaagg
     8041 acaaacgaaa tctaaattgg gtacttctga agctagaagt gctgttgatt cagttgttgc
     8101 agacaaattg ccattctatt tagaagaaaa aggacaattg tctaaatcac ttgtgaaaaa
     8161 agcgattaaa gcacaacaag caagggaagc tgcacgtaaa gctcgtgaag atgctcgttc
     8221 aggtaagaaa aacaagcgta aagacacttt gctatctggt aaattaacac ctgcacaaag
     8281 taaaaacact gaaaaaaatg aattgtattt agtcgaaggt gattctgcgg gaggttcagc
     8341 aaaacttgga cgagaccgca aattccaagc gatattacca ttacgtggta aggtaattaa
     8401 tacagagaaa gcacgtctag aagatatttt taaaaatgaa gaaattaata caattatcca
     8461 cacaatcggg gcaggcgttg gtactgactt taaaattgaa gatagtaatt ataatcgtgt
     8521 aattattatg actgatgctg atactgatgg tgcgcatatt caagtgctat tgttaacatt
     8581 cttcttcaaa tatatgaaac cgcttgttca agcaggtcgt gtatttatag ctttacctcc
     8641 actttataaa ttggaaaaag gtaaaggcaa aacaaagcga gttgaatacg cttggacaga
     8701 cgaagagctt aataaattgc aaaaagaact tggtaagggc ttcacgttac aacgttacaa
     8761 aggtttgggt gagatgaacc ctgaacaatt atgggaaacg acgatgaacc cagaaacacg
     8821 aactttaatt cgtgtacaag ttgaagatga agtgcgttca tctaaacgtg taacaacatt
     8881 aatgggtgac aaagtacaac ctagacgtga atggattgaa aagcacgttg agtttggtat
     8941 gcaagaggac caaagtattt tagataattc tgaagtacaa gtacttgaaa atgatcaatt
     9001 tgatgaggag gaaatctagt gagtgaaata attcaagatt tatcacttga agatgtttta
     9061 ggtgatcgct ttggaagata tagtaaatat attattcaag agcgtgcatt gccagatgtt
     9121 cgtgatggtt taaaaccagt acaacgtcgt attttatatg caatgtattc aagtggtaat
     9181 acacacgata aaaatttccg taaaagtgcg aaaacagtcg gtgatgttat tggtcaatat
     9241 catccacatg gagacttctc agtgtacgaa gcaatggtcc gtttaagtca agactggaag
     9301 ttacgacatg tcttaataga aatgcatggt aataatggta gtatcgataa tgatccgcca
     9361 gcggcaatgc gttacactga agctaagtta agcttactag ctgaagagtt attacgtgat
     9421 attaataaag agacagtttc tttcattcca aactatgatg atacgacact cgaaccaatg
     9481 gtattgccat caagatttcc taacttacta gtgaatggtt ctacaggtat atctgcaggt
     9541 tacgcgacag atataccacc acataattta gctgaagtga ttcaagcaac acttaaatat
     9601 attgataatc cggatattac agtcaatcaa ttaatgaaat atattaaagg tcctgatttt
     9661 ccaactggtg gtattattca aggtattgat ggtattaaaa aagcttatga atcaggtaaa
     9721 ggtagaatta tagttcgttc taaagttgaa gaagaaactt tacgcaatgg acgtaaacag
     9781 ttaattatta ctgaaattcc atatgaagtg aacaaaagta gtttagtaaa acgtatcgat
     9841 gaattacgtg ctgacaaaaa agtcgatggt atcgttgaag tacgtgatga aactgataga
     9901 actggtttac gaatagcaat tgaattgaaa aaagatgtga acagtgaatc aatcaaaaat
     9961 tatctttata aaaactctga tttacagatt tcatataatt tcaacatggt cgctattagt
    10021 gatggtcgtc caaaattgat gggtattcgt caaattattg atagttattt gaatcatcaa
    10081 attgaggttg ttgcaaatag aacgaagttt gaattagata atgctgaaaa acgaatgcat
    10141 atcgttgaag gtttgattaa agcgttgtca attttagata aagtaatcga attgattcgt
    10201 agctctaaaa acaagcgtga cgctaaagga aaccttatcg aagtattcga gttcacagaa
    10261 gaacaggctg aagcaattgt aatgttacag ttatatcgtt taacaaacac tgacatagtt
    10321 gcgcttgaag gtgaacataa agaacttgaa gcattaatca aacaattacg tcatattctt
    10381 gataaccatg atgcattatt gaatgtcata aaagaagaat tgaatgaaat taaaaagaaa
    10441 ttcaaatctg aacgactgtc tttaattgaa gcagaaattg aagaaattaa aattgacaaa
    10501 gaagttatgg tgcctagtga agaagttatt ttaagtatga cacgtcatgg atatattaaa
    10561 cgtacttcta ttcgtagctt taatgctagc ggtgttgaag atattggttt aaaagatggt
    10621 gacagtttac ttaaacatca agaagtaaat acgcaagata ccgtactagt atttacaaat
    10681 aaaggtcgtt atctatttat accggttcat aaattagcag atattcgttg gaaagaattg
    10741 gggcaacatg tatcacaaat agttcctatc gaagaagatg aagtggttat taatgtcttt
    10801 aatgaaaagg actttaatac agatgcattt tatgtttttg cgactcaaaa tggcatgatt
    10861 aagaaaagta cagtgcctct atttaaaaca acgcgtttta ataaaccttt aattgctact
    10921 aaagttaaag aaaatgatga tttgattagt gttatgcgct ttgaaagaga tcaattaatt
    10981 accgtcatta ctaataaagg tatgtcatta acgtataata caagtgaact atcagatacc
    11041 ggattaaggg cagctggtgt taaatcaata aatcttaaag ctgaagattt cgttgttatg
    11101 acagaaggtg tttctgaaaa tgatactata ttgatggcca cacaacgcgg ctcgttaaaa
    11161 cgtattagtt ttaaaatctt acaagttgct aaaagagcac aacgtggaat aactttatta
    11221 aaagaattaa agaaaaatcc acatcgtatt gtagctgcac atgtagtgac aggtgaacat
    11281 agtcaatata cattatattc aaaatcaaat gaagaacatg gtttaattaa tgatattcat
    11341 aaatctgaac aatatacaaa tggctcattc attgtagata cagatgattt tggtgaagta
    11401 atagacatgt atattagcta aaaactatat gcaatcacga aattaaatga taaaatacag
    11461 taatgttaaa ttttgactaa attcaaggga tttatattaa atgctgacca agtacttatc
    11521 gttaaattag cgatatactt tgaccaaact aatataaatc tcttgtattg tataagaaat
    11581 gatgatgtat ctctatattt actgaagttt caattcggtc taattttata gaaggtgcat
    11641 gattcatgta gaggatgcga ggggtttatt ttgaaagatt tcgatagttt aattcctgga
    11701 tggtttaaag aatttgtcca tgttggtacc gatttaatat ggtctcaata tttaattggt
    11761 ctattattga cagctggatt cttctttaca attagttcta aattcgttca attacgaatg
    11821 ttacctgaaa tgtttagagc tttagtagaa cgtccagaaa ctttagaaga tggtaagaag
    11881 ggtatttcgc cattccaagc atttgctatt agtgctggtt cgagagttgg tactggtaat
    11941 attgctggtg ttgcgactgc gattgtttta ggcggtccag gtgcagtgtt ttggatgtgg
    12001 gttattgcat ttataggtgc agcgagtgca tttatagaag cgactttggc tcaggtttat
    12061 aaagtacatg ataaagatgg tggattccgt ggtggtccag cttactatat tactaaaggt
    12121 ttaaatcaaa aatggctagg tatcgtattt gcgattttaa ttacaattac atttgcattt
    12181 gtatttaaca cagtgcaatc taatacaatt gcggagtcgt taaatacgca atataatatt
    12241 agtccagtaa tcacaggtat tattttagca atcgtaacag ctattattat atttggtggt
    12301 gtacgtagta ttgctacgtt atcttcgtta attgtaccga ttatggctat catttacatt
    12361 ggtatggttt tagtaatatt gctatttaat ttagatcaaa ttgttcctat gataggtacg
    12421 attattaaaa gtgcatttgg tatcgaacaa gtaactggtg gcgctgtagg tgctgcggtt
    12481 cttcaaggta tcaaacgtgg tttattctct aacgaagctg gtatgggttc tgcgccgaat
    12541 gcagcggcaa ctgctgccgt gccacaccct gttaagcaag gtttaatcca atcattaggt
    12601 gtgttctttg atacaatgtt ggtttgtaca gcaactgcaa tcatgatttt actatattca
    12661 ggattgaaat ttggtgataa cgcacctcaa ggtgttgcag ttactcaatc agcacttaat
    12721 gagcatttag gttctgctgg aggtattttc ttaacaatag cagttacact gtttgcattt
    12781 tcatctgttg taggtaatta ctattacggt caatctaata ttgaattttt atcaacaaac
    12841 cgtgtaatat tatttatctt tagatgtctt gttgtagtac ttgtctttgt cggtgcagtt
    12901 gtaaaaacag aaacagtatg gaatacggca gacttattta tgggcttaat ggcaattgta
    12961 aacattattt ccattatagg actgtccaat gtagcttttg cattgatgaa agattatcaa
    13021 aagcagaaaa aagaaggcaa gaatcctgtc tttaaacctg aaaacttaga aattaactta
    13081 tttggaatta gtgcttgggg cgctaacaaa tataagaact ctgataaata aatattttta
    13141 atgtaacgat tcattatata aaaatcaaat aaaccctgag gttttcaaat taaagcgaaa
    13201 atctcagggt tttaaatttg tactcaataa tcatctgtat cattacacta gttaatccaa
    13261 gatttgatta tatattaata tagtaaggtt gagatttatt tcctccattg gtgtgcaaag
    13321 actataccat tgataagaca tattgttgga tagatgaata taaatttatt ttagctttgc
    13381 acaatttaat agtacgtttt agtttgtatt gagtattaat tcagataata tataaataaa
    13441 tagaattatt tgtaaatatg ggagtcagat ttttttatta tagttattcc actttgagag
    13501 gcatcgaaat taaattaaga tgtatcatat aggataggcg tgtaatagaa cacaagtatt
    13561 taatttatta tactttcaag ttaggcattt ccgatatata atcttaataa tagaaaaata
    13621 ggtgatgata atgggagaat atattgttac taaaacattg aacaacaatg tcgtagtatg
    13681 tactaataat gatcaagaag ttattttaat cggtaaaggt attggtttta acaaaaaaga
    13741 gggaatgacg ttaaacgacc aaactattac aatagagaaa atttataaat tagagagtga
    13801 gcaacaaaaa gcacattata aaagtttagt tgaaatcgct gatgataatg tattacaagt
    13861 aattattgat tcgttaaatt ttatttctaa tactgcgatg aatgttgatt caaaacaact
    13921 tgtagtttca ttaacggatc atattatatt tgcatataaa cgcttaaaac aaaatcaagt
    13981 tattagcaat ccatttgtta tggaaactat gcagttatat agtgatgcat atcatattgc
    14041 taaacaggta attgatcagt taaatgcagc attagatgta cattttcctg aagatgagat
    14101 aggatttatt gcattacata ttgcatctaa cacagaagat ttatctatgc atgagatgac
    14161 tttgatcaat aatgttatta aaaaaggtat agatatcatt gaatcagacc ttgtgacaac
    14221 tgttgataag gaatcattac aataccaacg ttttataaga catgtacaat ttttaattcg
    14281 ccgattaaga agaaaagaat atatacatgc acaagatgat tttgtgtcta tgattaaaaa
    14341 tcactatccg atttgctata acacagcata taaaatttta actatgatac aaaaacaatt
    14401 tgatgttact atcagtgagt ctgaaattat atatttaaca ttacacattc atcattttga
    14461 agaaaggatt aatcattcct aaattaagtg cattatacgg gcgtttcgtt actgtaaagg
    14521 gtatttgtat ggtatcattg atgttagtaa ttttacataa gtggactgtt tttatacaac
    14581 atcttatgaa tattttaagt ggtggtgaat ctataattga atgaaaatga aaagaatata
    14641 agaaagaact ttttaaaatt taccgaatca cggtatatga agtttgttgg tgggaatgat
    14701 ttagtcttct cattaatagc tctagtattg ttgggtattg ttatttttat tttcgaaaaa
    14761 gtatcatacg tttttgatcc ttttatcatc gtttttaaga cgatagcagc acctatcatc
    14821 gtctctttaa ttctattcta tctatttaac ccaatcgtaa atatgatgga acgttataga
    14881 ataccaagag ttgcaggtat ttctattatt tatctagctg tagtaggtgt tattacgtta
    14941 attgttaatt tattgatacc tattattggt tcgcaagtag atagtttagt taaaaattca
    15001 ccgcaatatc tagaaaaatt aattaattct attgataaaa tagcaaataa tacgtttttc
    15061 tcttcgtatt atagtcaaat taatgattgg ttaaattctt tacctaagaa aataccatct
    15121 atgttaagtg aatttacaga tggctttggg tctaaaattg caacgtttgc agaaacgatt
    15181 gctaatattg gcgttgtgat tgtaacaaca ccatttgtac tattctttat gcttaaagat
    15241 ggacatcact tcaaagaatt ttcaacgaat attatgccac cgaaattccg aaaagatttt
    15301 catgatctac ttgaaaaaat gagtgttcaa gttggttcat acattcaagg acaaattatt
    15361 gtttcattct gtatcggtat attgttgttt atcggttatt cggttatcgg gttgaaatat
    15421 agcttagtat tagctagtat tgcggcagtt acaagtgttg taccatattt agggcctaca
    15481 atagcgattt caccagctat tgtaatagct gctataactt cgccgtggat gctcttaaaa
    15541 ttagcagtag tatggacttt agtacaattt gttgaagggc acttcatttc accaaatatc
    15601 atgggtaaaa cacttaagat tcatccactt acaatcattt tcattttact ttgtgcaggc
    15661 aaattgcttg gtattgtagg cgttatttta ggtattccgg gatatgctat tttaaaagta
    15721 ttagttactc atttattcca attatttaaa cgtcgataca atcgtttcta tggtaatgat
    15781 gtaggtgaat atgatattaa agaaagtaat aaaatagttg aataagtaat taaaaatacc
    15841 aatagactat acgtttgttg gtatttttta tggtgcttat aatgttgggc actcacattt
    15901 atgattatca gcacatgttt agcttataaa tttttacgaa agtttagccg tttctaaagt
    15961 acataataat aaaacgagta tttgccactt gattagtact tcattattat gtcgaaaata
    16021 aaaacaagtg gtatttttaa tatattaaga agcactcata atcagctgtt aattaataat
    16081 atttttcata agtattgatt catcattttc tttatgttaa atatgaatca gtatagataa
    16141 ccatattgtt ctgtttgaga tagaaatatt ttctatttac ttcttaatac agatgtcaat
    16201 atgacaaaag tgttatataa atcaaaggta aatgatatgc tatttttatg gtttatatga
    16261 tatattttga tttataacag aaataattag aattgatgtg aaaaaatgaa tcaggaagtt
    16321 aaaaacaaag tattttcaat cttaaaaatt acgtttgcta cagctttatt tatttttgta
    16381 gtaatcacgt tgtatcgaga gttatctgga attaacttta aagatacttt ggttgaattt
    16441 agtaaaatca accgtatgtc ccttgtctta ttatttattg gtggtggggc atcgcttgtt
    16501 attctctcaa tgtatgatgt gattttatct agagctttaa aaatggatat ttcattagga
    16561 aaagttttaa gagtaagtta tatcattaat gcattaaatg cgattgtagg ctttggtggc
    16621 tttattggtg ccggtgtaag agcaatggtt tacaaaaact atacgcatga taaaaagaaa
    16681 ttggttcact ttatttcatt aatactgatt tcaatgttga caggtttaag cttattatca
    16741 ttgctaattg tattccatgt tttcgatgca tctttaatct tagataagat tacatgggta
    16801 agatgggtat tatatgtagt gtcatttttc ttaccattat tcattattta ttcaatggtt
    16861 agaccacccg ataaaaacaa tcgttttgta ggattgtact gcactttagt gtcgtgtgtt
    16921 gaatggttag cagctgcagt tgtattatat ttctgtggtg taattgttga cgctcatgta
    16981 tcattcatgt cctttattgc aatatttatc attgctgcat tatcaggttt agtcagcttt
    17041 attcctggtg gtttcggcgc tttcgattta gttgtattac taggatttaa aactttaggt
    17101 gtccctgagg aaaaagtatt attaatgcta cttctatatc gttttgcgta ctattttgta
    17161 ccggtaatta ttgcattaat tttatcatca tttgaatttg gtacatcagc taagaagtac
    17221 attgagggat ctaaatactt tattcctgct aaagatgtta cgtcattttt aatgtcttat
    17281 caaaaggata ttattgctaa aattccatca ttatcattag caattttagt attctttaca
    17341 agtatgatct tttttgtaaa taacttaacg attgtttacg atgctttata tgatggaaat
    17401 cacttaacgt attatattct attggcaatt catactagtg cttgtttatt acttttactg
    17461 aatgtagttg gtatttataa gcaaagtaga cgtgccatta tctttgctat gatttcaatt
    17521 ttattaatca cagtggcgac attcttcact tacgcttcat atattttaat aacatggtta
    17581 gctattattt ttgttctgct tattgtagct ttccgtagag cacgtaggtt gaaacgccca
    17641 gtaagaatga gaaatatagt tgcaatgctt ttattcagtt tatttatttt atatgttaac
    17701 catatattta ttgctggaac gttatatgca ttagatattt atacgattga aatgcataca
    17761 tctgtattgc gctattactt ctggcttacg attttaatca tcgctatcat cataggtatg
    17821 attgcatggt tgtttgatta tcaatttagc aaagtacgta tttcttctaa aattgaagat
    17881 tgcgaggaga ttattaatca gtacggcggt aattatttga gtcacttgat atatagtggt
    17941 gacaagcagt ttttcactaa tgaaaataaa acagcatttt taatgtatcg ttataaagca
    18001 agttcattag tggttcttgg agatccgtta ggtgatgaaa atgcctttga tgaattgtta
    18061 gaagcattct ataattacgc tgagtattta ggctatgatg ttatattcta tcaagttaca
    18121 gatcaacaca tgcctttata tcataatttc ggtaaccaat ttttcaaatt aggtgaagaa
    18181 gcaattattg atttaacgca attttcaatt tcaggtaaaa aacgccgtgg atttagagcg
    18241 actttaaata aattcgatga acttaatatt tcgttcgaaa ttattgaacc accgttttca
    18301 actgaattta taaatgaact tcaacatgta agtgatttat ggctagataa tcgtcaggaa
    18361 atgcatttct ctgttggtca atttaatgaa gaatacttat ctaaagcgcc aattggtgta
    18421 atgcgaaatg aagaaaatga agtaattgca ttctgtagtt taatgccaac atactttaat
    18481 gatgccattt cagtcgattt aattagatgg ttgccagagt tagatttacc attaatggat
    18541 ggattatact tgcacatgtt actttggagt aaagaacaag gttatacaaa atttaatatg
    18601 ggtatggcaa cgttatcaaa cgttggtcaa ttgcattatt catatttaag agaacgactt
    18661 gcaggccgtg tctttgaaca tttcaacggt ctatatcgtt tccaaggatt acgtcgttat
    18721 aaatctaaat ataatccgaa ttgggaacca cgctttttag tttatcgtaa agataattcg
    18781 ctttgggaat cactttctaa agtaatgcgt gtaatacgtc acaaataatt aaaatccaag
    18841 tgctaagagg tatacagtta tgcctgaagc gcttggattt tttggtttct ataaagaatg
    18901 atttataaaa aacggtacag ataagaatat ttaagtttcc tatctgtacc gtattttaat
    18961 attgaaatga gcttaagtta agtcgcctaa cttttattat cagtccaatc agtttcatca
    19021 agtataaatg ttattgctta tttttgtatt cttggcgtat tttttgttct tctgcatagc
    19081 gctctggatt tttcttataa aaatcttggt gatagtcttc ggctttgtaa aattgtgacg
    19141 ctggtaatat ttttgttgca attgccttat cagcattaat cgtattttta agctgctcga
    19201 tataagtctc agcgagttct ttttgatgat cattagtgta gaaaatagct gtttgatatt
    19261 gagggccacg gtcttgatat tgaccacctg tatctaatgg gtcaatgact gagaaaaata
    19321 tttctaataa cttattgtat gagaataatg caacatcata ttgaatttca acagtttcta
    19381 aatgaccact cgtacctgat tttacttgtt cgtaagtagg attttcaata tgtccgccca
    19441 tatatccaga agttactttt tctatgccgt caaaggtgtc aaatggtttc gtcatacacc
    19501 aaaagcaacc tccggcaaaa taagctgtat taatattcat ttttgacatc ctttcattag
    19561 accttagtac gatttattaa gaaatcactt gctttttgaa ttgtttttat ataacgttaa
    19621 tatgtgatta ttatagtaca caaaaatcta tttttgaaga tataaggtag gtaaatatgg
    19681 ataaagaaac taatgacaac gaatatagac gtcaaagtga acatcgcact tcggcgccta
    19741 agcgaaaaaa gaagaagaaa attaggaaat tacctatcat tcttctgatt gttgtaattt
    19801 tacttatcgc attagttgta tatattgtgc atagttacaa tagcggtgta gaatatgcca
    19861 agaaacatgc gaaagatgtt aaagtacatc aatttaatgg accagtaaaa aatgatggta
    19921 aaatttctat tcttgtactc ggtgcagata aagcacaagg tggacaatca agaacagatt
    19981 ctatcatggt tgttcaatat gactttatca ataaaaagat gaaaatgatg tctgtcatgc
    20041 gtgatattta tgcagatatt ccaggatatg gaaaacacaa aattaattca gcatacgctt
    20101 taggtggtcc agagctactt agaaaaacac ttgataaaaa tttaggaatt aatcctgaat
    20161 attatgcagt agttgatttt actggatttg agaaaatgat tgatgaatta atgccagaag
    20221 gtgtaccaat taatgtcgaa aaagatatgt cgaaaaatat tggtgtatct ttgaaaaagg
    20281 gtaaccatag gttgaatggt aaagaattac ttggttatgc aagattccgt cacgaccctg
    20341 aaggtgactt cggacgcgtg cgacgtcagc aacaagtgat gcaaacattg aaaaaagaaa
    20401 tggttaattt tagaacagtt gttaaattac caaaagtcgc aggtatttta agaggctatg
    20461 tgaatacaaa cattcctgat tcagggattt tccaaacagg tttgagtttt ggtatccgag
    20521 gtgaaaaaga tgttaagtca ttgactgtgc caatcaagaa ctcatacgaa gatgtcaata
    20581 caaatactga tggtagtgca ttacagatta ataaaaacac aaataaacaa gctattaaag
    20641 actttttaga tgaagattaa aaataaacaa ggcgatttct atcatactca gatagaagtc
    20701 gccttgttcg ttttcaaaga attatttggc atgcatctta tgaagaacta ttgatctgac
    20761 tttcttacgc cagccacacc ataatggttt ggtttcattt cttctataac aacgtgaatt
    20821 gcttgtctat ttgctcccgt tgttttttct acggcgtcag taacttcgct aactaaattt
    20881 tttaattgtt catccgaacg accttctaat aattttacat tgacgattgg catcatccaa
    20941 acctcctaat cattattaat ttgagtatat catgtaatac ttaaaaattc atttgcaaat
    21001 taacagaaca cttgttctaa aatagttgaa atagaacacg tgttcgtata taatagaatt
    21061 caagtaaggg aggaataaca gtgtataatt atcatttatt agaagatagg gatgttctat
    21121 gtattgacca aaaaagtttt tttgcgagtg tttcttgtat tgaaaaaggg ctagatccat
    21181 tagaaacaaa gttagctgtt gttgcagata ctaagcgtca gggttctgta gtattggctg
    21241 cgacacctaa attaaaagaa ttaggcatca agacagggtc gcgattgttt gaaataccac
    21301 atagaaatga tatttacatt atcaatccaa gtatgcgtaa atatcttaat gtttcagttg
    21361 ctatttctaa gattgcattg cgttatattc cacctgaaga tttacaccaa tatagtattg
    21421 acgaattttt tatggatgtt actgatagct atcatagatt tagttctaca gtacatgcat
    21481 tttgcgaaag acttaaacgt gaaatttatg aagaaacagg catttattgt actgtgggca
    21541 ttggttctaa tatgttatta agtaaaattg ctatggatgt tgaagcgaag catagtcaaa
    21601 atggtatagc tgaatggcga tatcaagatg taccaacgaa attatggcca attcagccct
    21661 tgcgagattt ttggggtatt aatcgtcgaa cagaagccaa attgaataaa agaggaattt
    21721 ttactatagg agatttagcg aaatatccat ataaattttt aaaaaaagag ttcggtattt
    21781 taggtgttga tatgcatcta catgcgaatg ggatagatca gagtaaagta cgtgaaaagc
    21841 acaagatcag caatccatcg atatgcaaaa gtcaaatatt aatgagagat tatcattttg
    21901 atgaagcaaa agtagtaatg caagagttaa ttgaagatgt tgctagcaga gttcgagcaa
    21961 gaaaaaaagt ggcaagaacg atacattttg cctttggcta tagtgatgaa ggcggtgtac
    22021 ataagcaata tactttgaaa gatccaacaa acttagaaaa agatatttat aaagtagtaa
    22081 tgcatttcgc agataaatta tgtaataaac aagcactata tcgtacgcta agtatatctt
    22141 tgagtcaatt tattaatgag gatgagcgac agttaagtct gtttgaagat gaataccaac
    22201 gcaaacgtga cgaatgtcta gctaaaacga tagaccaatt acatttgaaa tacggcaaag
    22261 gtattgtgtc caaagcagta tcgtttacag aagcaggtac aaaacacggc agattaggtt
    22321 taatggctgg acataaaatg taatgattat acggtttaag gaatatataa ctgtgattcg
    22381 tataaaataa gtctctaaag ataaatattt catatatcac aatagatttc acaataatat
    22441 ctaagaatac atgggaattt atcaaaagag acttaataat tattggatat aacaatcaaa
    22501 atcactcaat gcttgcatac cgcgttctcg gtcagtagga tttttgaaac taatttttaa
    22561 agcaccgtat atatcttcgc gtacttctaa gattcttaag ttgcttatag atatgttatg
    22621 taaactcagg atataagtca ctttacttat catacctgat tcatccggaa tatccacata
    22681 tagatcatac gcagtattta gtccacctag ttgtttagcg ggcagtgcgt cacgatacga
    22741 tttagcttcg gcaaaaaatg ataacaattt ttcagaatca ttgctttcaa ttagtctttc
    22801 taaatcttga aactgacttt ttagctgtcg aatcatttct aaaatatacg ttttattact
    22861 caaggtgata tctttccaca tttgtgcatt actactagct atacgagtga tatcacgaaa
    22921 accaccagct gcaagtttat tgactaaatg atgttcttga ccgttctttt gactaacatg
    22981 aactaaacta gatgcaacga tatgaggtaa atgacttacg acgcttgtta cgtagtcgtg
    23041 ttcttcagca gtagttacaa taaatttagc aagagtaggt gataacagtt cttttaacgt
    23101 gtttgctgct tgctcatttc ttgcctcatt gtagactaaa atataataag cgttttcaaa
    23161 taagtgcttt ttagcattta gtacaccaga tttatgacta ccagccattg gatgaccact
    23221 gactagatga atattatgct ttaataaatt gcattcgtgt tgctgtatca ttgctttagt
    23281 actaccagta tcagaaacaa taacaccagg tttagttggc atatctataa gcttgctaag
    23341 atatttattt gtgatagcaa caggtgttgc ataaataatt acatcggctt ttttaatagc
    23401 ttcactataa tttaaacatt tttcattaat aataccgatt gatttagctt tatctaactg
    23461 agaagtatct gcatcgtatg caataatatt agtattaggc ttatggtatt ttatattgct
    23521 agcaagactt ccaccaatta atccaagccc aacaaataaa actgttgtca tataaatcac
    23581 cttatttcga aattttcaga ataataacat tgtaaatgag ctgttgacac agtgcaatag
    23641 taaataaaaa tcgataatag cattaataga taaacggaga taaatcatct acaataaaga
    23701 gtatagtaac acaatggcaa cggaggggta aatcaatgga accaatatta gaaatgatta
    23761 aaacattaac aggtattaat agtccttcag gagacacaga agaagcaatt caatttgtcg
    23821 aaaaatatgc aaaagacttg ggttatcaaa caacactaac aaataaaggt gcgttattaa
    23881 taacagtgcc aggcaaaaat gatgaagtac aacgctgtat tactgctcat gttgatactt
    23941 taggtgcaat ggttaaagaa attaaagaag atgggcgctt agcaatagaa ttaattggag
    24001 gattcacgta taacgcgatt gagggtgaat attgccaaat taaaactgat gctggtcaaa
    24061 tatatacagg aacaatttgt ctgcatgaaa caagtgttca tgtatataaa aataatcatg
    24121 aaataactag agaccaaaag catatggaaa taagagttga tgaagtaact acatcagaag
    24181 aagatacaaa gagtttaggt atttcagtag gtgattttgt tagctttgat ccacgtacag
    24241 ttatcacgtc atcaggtttc attaaatctc gccatttaga tgataaagct agcgtagcga
    24301 tgatactaca attactaaag aaattaaaag aagagcaaat aatattacca catacaacgc
    24361 aattttatat ttctaataac gaagaaatag gttacggtgc aaatgcatca attgattcga
    24421 aaatcaaaga atatattgca ttagatatgg gcgcgttggg agacggtcaa gcatcggatg
    24481 aatatacagt ttctatttgt gccaaagatg cttcaggtcc atatcataag caattgaaat
    24541 cgcacctagt taatctttgc aaaataaata acattccata taaagtcgac atatatccat
    24601 attatggttc agatgcttca gcagctttac atgctggtgc ggatatcaga catggtttat
    24661 ttggcgctgg cattgaatca tctcatgcaa tggaacgaac acatattgat tctattaaag
    24721 cgacagagaa attactatat gcatattgct tatcaccaat tgagtaaaca attagtgttg
    24781 acaaatgtga acgacctatg taatataatg aactataaaa ataattagaa ttttctaaag
    24841 aaatagtagc agatatgaaa cgtagcaaat agaaagctaa tgggtgatgg gaattagcac
    24901 gccatatctt gtgaattgga ctttggaaaa caattgaatg agttttgaaa gtgaacatga
    24961 attatgttaa ctaaggtggc accacggtaa cgcgtcctta caggtatatg cgttatgtgg
    25021 tgtcttttta tttagacaaa atgtagtagt taattaaagg tagcaacaga aagttagtgg
    25081 atgatgtgaa ctaacaccga gattaatgaa attgggtttt gtctgcaaca gaaaaattat
    25141 atatagtaaa gagtgaacta tgaatatttc gaatattcgg ttaatttagg tggtaccacg
    25201 cgtcagcgtc ctttatattg ataaggatgc tggcgctttt ttgaaaggag cgtatagaat
    25261 ggatatattt tataaaaaaa taaaagcaaa tgtaacgcca gaagttttag cacaacttca
    25321 ttccaagaag atcattttgg aaagtacaaa tcaacaacaa actaaaggtc gctattcagt
    25381 tgttattttt gatatttatg gcactttaac tttagataat gatgtattat cagtaagcac
    25441 tttaaaagaa tcgtatcaaa tcattgaaag accgtaccat tatttaacga ctaaaataaa
    25501 tgaagactac cataatattc aagatgagca acttaagtca ttaccgttta tatctggata
    25561 tgttgggacg tgtagctttg atttagtaag acatgaattt cctaaattgc aatcaataca
    25621 attagaagat cacaagcagc acgatgtaag gttatatatg gttgaacaag tttatgtatt
    25681 tgaccattac aaagatgagt tatatatcat cgcgacgaat caattttcaa attcaacaaa
    25741 atcagatctt gagaatcgag ttaataagtc tatcgaagac ttaactaaaa tccaaccatt
    25801 catgcctaca caagattttg attttaaaac taaagaaatt caatcaaata tttctgaaga
    25861 aagatttatc gaaatgattc agtatttcaa agagaaaata acagaagggg atatgttcca
    25921 agttgtgcca tcaagaattt acaaatatgc gcatcatgct agtcagcatt taaatcaact
    25981 ttcgtttcaa ctgtatcaaa atttaaaacg acaaaaccca agtccatata tgtattatct
    26041 taatatcgat aaaccctata ttgtcggtag ttctcccgaa agtttcgtaa gtgtcaaaga
    26101 tcaaattgta acaactaatc ctattgcagg tacgattcaa cgtggtgaga cgacacaaat
    26161 agataatgag aatatgaaac aactacttaa tgatccaaaa gaatgcagcg aacatcgtat
    26221 gctagttgat ttaggacgta atgatattca tagagtaagt aaaatcggta cctcaaaaat
    26281 tactaaatta atggttattg aaaaatatga acatgttatg catatcgtaa gtgaaatcac
    26341 aggtaaaata aatcaaaatt tatcaccaat gacagttatt gcgaatttat taccaacagg
    26401 taccgtttca ggtgcaccaa aattacgtgc aattgaaaga atatatgaac aatatccaca
    26461 taaacgaggc gtttatagtg gtggtgttgg atacataaat tgtaatcata acttagattt
    26521 tgctttagca attcgaacga tgatgataga tgagcagtat atcaacgtag aagctggttg
    26581 tggcgttgta tatgattcta ttcctgaaaa agaactaaat gaaacgaaat tgaaagctaa
    26641 aagcttattg gaggtgagcc catgatctta gttgtagata attatgattc ctttacatat
    26701 aacctagtgg atattgttgc tcaacatact gacgtcattg ttcaataccc tgatgatgat
    26761 aatgtgctga atcaatcggt ggacgctgtt attatatctc ctggtccagg gcatccatta
    26821 gacgatcaac agttgatgaa aatcatatca acctatcaac acaaacccat tttaggtata
    26881 tgtttagggg ctcaggcact gacttgttac tacggtggag aagtcattaa aggcgacaag
    26941 gttatgcacg gcaaagttga tactataagt atcacttcaa atactcacaa agtgttatat
    27001 caagatgttc cagaacagtt ttcaattatg agatatcatt cattaataag taaccctgac
    27061 aattttccag aagaattgaa aattactgga cgtaccaaag attgtataca gtcatttgag
    27121 cataaagaaa gaccgcatta cggtattcag taccatcctg aatcatttgc tacagactat
    27181 ggtgtcaaaa taattacaaa ttttattaat ctagtgaagg aaggatgaaa accatgacat
    27241 tactaacaag aataaaaact gaaactatat tacttgaaag cgacattaaa gagctaatcg
    27301 atatacttat ttctcctagt attggaactg atattaaata tgaattactt agttcctatt
    27361 cggagcgaga aatccaacaa caagaattaa catatattgt acgtagctta attaatacaa
    27421 tgtatccaca tcaaccatgt tatgaagggg ctatgtgtgt gtgcggcaca ggtggtgaca
    27481 agtcaaatag tttcaacatt tcaacgactg ttgcttttgt tgtagcaagt gctggcgtaa
    27541 aagttataaa acatggtaat aaaagtatta cctcaaattc aggtagtacg gatttgttaa
    27601 atcaaatgaa catacaaaca acaactgttg atgatacacc taaccaatta aatgaaaaag
    27661 accttgtatt cattggtgca actgaatcat atccaatcat gaagtatatg caaccagtta
    27721 gaaaaatgat tggaaagcct acaatattaa accttgtggg tccattaatt aatccatatc
    27781 acttaacgta tcaaatggta ggcgtctttg atcctacaaa gttaaagtta gttgctaaaa
    27841 cgattaaaga tttaggtaga aaacgtgcaa tcgttttaca tggtgcaaat ggtatggatg
    27901 aagcaacact atctggtgat aatttgatat atgaattgac tgaagatgga gaaatcaaaa
    27961 attacacatt aaatgcgact gattatggtt tgaaacatgc gccgaatagt gattttaaag
    28021 gcggttcacc tgaagaaaat ttagcaatca cactgaatat cttgaatggt aaagatcagt
    28081 caagtcgacg tgatgttgtc ttactaaatg cgggtttaag cctttatgtt gcagagaaag
    28141 tggataccat cgcagaaggc atagaacttg caactacatt gattgataat ggtgaagcat
    28201 tgaaaaaata ccatcaaatg agaggtgaat aatatgacga ttttatcaga aattgttaaa
    28261 tataaacagt cacttttaca aaatggctat tatcaagaca aacttaatac cttgaaaagt
    28321 gtgaagattc agaataaaaa atcttttata aacgcaattg agaaagaacc aaagctagca
    28381 attattgcag aaatcaaatc gaagagtcct acagttaatg acttacctga acgagattta
    28441 tcgcaacaaa tctcagatta tgaccaatat ggtgcaaatg ccgtgtctat tttaactgat
    28501 gaaaagtact ttgatggtag ttttgaaaga ttacaagcat tgacgacaaa aacaacatta
    28561 cccgtattat gcaaagactt tattatagac ccgcttcaaa ttgatgttgc taaacaagct
    28621 ggtgcatcta tgattttatt gatcgttaac atcttatctg ataaacaatt gaaagattta
    28681 tataactacg ctatatcgca aaatctagaa gtgttagttg aagtacatga tcgccatgaa
    28741 ttagaacgtg cctataaggt taatgctaaa ttgattggtg tgaataacag ggacttaaaa
    28801 cgatttgtca caaatgtgga acatacaaat actattttag aaaataaaaa accaaatcat
    28861 cattatattt ctgaaagtgg tattcacgat gcatctgatg taagaaaaat cttgcatagt
    28921 ggtatcgatg gcttactaat aggtgaggcg cttatgcgtt gtgacaatat atctgaattt
    28981 ttaccacaac tgaaaatgca aaaggtgaag tcaagatgaa attgaaattt tgtggcttta
    29041 catcaataaa ggatgttaca gcggccagtc aattacctat tgatgcgata ggtttcatcc
    29101 attatgaaaa aagtaaaagg catcaaacaa ttacccaaat aaaaaagtta gcgtctgctg
    29161 ttccaaatca tatcgataaa gtatgtgtca tggtaaatcc tgatttaaca acaattgaac
    29221 acgtattaag caatacgtca attaacacaa tacagttaca cggcacagaa tctattgatt
    29281 ttatacagga aattaaaaag aaatattcaa gcattaaaat cactaaagct ttagctgcag
    29341 atgaaaacat aatccaaaac ataaataaat ataaagagtt cgtagattta tttattatcg
    29401 acacaccctc agtgtcgtat ggtggtaccg gtcaaacata tgactggact attttgaagc
    29461 acataaaaga cataccttac ttgatagcag gaggcattaa ctctgaaaat attcaaaaag
    29521 ttaatcaact taaattatca catcaaggtt atgatcttgc atcaggtata gaagtaaatg
    29581 ggcgaaaaga tatagaaaaa atgacagcaa ttgtaaatat tgtgaaagga gatagagaaa
    29641 atgaataaac aaatacaaac agaagcagat gaattaggtt tctttggtga atacggaggg
    29701 caatatgttc cagaaacatt aatgccagca attattgagt tgaaaaaagc ttataaagag
    29761 gcaaaagcag acccagagtt tcaaagagaa ctggaatact atttatcaga gtatgtagga
    29821 cgcgcgacgc cacttacata tgctgcatca tatactgaaa gcctaggtgg cgctaaaata
    29881 tatttgaaac gagaggatct aaatcataca ggcgcccata aaattaataa tgcgttaggt
    29941 caagcgttgc ttgctaaaag aatgggcaag aagaagcttg ttgctgaaac tggtgcgggt
    30001 caacatggtg tagctagtgc tacggttgct gcattatttg atatggaact tgttgtcttt
    30061 atgggaagtg aagatattaa aagacaacaa cttaatgtat ttagaatgga attacttggt
    30121 gcaaaggttg tggcagttga agatggtcaa gggactttat cggatgcagt taataaagca
    30181 ttgcaatatt gggtaagtca tgtagatgat acacattatt tattaggttc tgcattaggt
    30241 ccagacccgt tcccaacgat tgttagagat tttcagagtg tgattggtaa agaaataaaa
    30301 tcacagatat tgaagaaaga aggtcgactt ccggatgcaa ttgtagcatg tatcggtggt
    30361 ggctcaaatg caatcggtac attttatcca tttattaaag atgatgttgc attatacggt
    30421 gttgaagccg caggtcaagg cgaggatact gataaacatg cacttgcaat tggcaaagga
    30481 tcacctggcg tattacatgg tactaaaatg tatttaattc aagatgaagg tgggcaagtg
    30541 caactagcac attctatttc agcaggactt gattatcctg gtattgggcc agaacattct
    30601 tattaccacg acattggtag agtaactttt gaaaatgcaa gtgatacaca agcaatgaat
    30661 gctttaatca actttacaaa acatgaaggt attatacctg caattgaaag tgcacatgca
    30721 ctgagttatg ttgaaagact agcgcctacg atgtcgaaag aagatattat tgtagtaact
    30781 atttctggac gtggcgataa agatatggaa acaattagac aatatatggc agagcgaggt
    30841 cttgcaaatg actaaattat ttatacctta tattatgggc aataaagatt tgattgaaaa
    30901 tgcaacattg ttgagtgaaa atggtgcaga tataattgaa attggtgtac ctttctctga
    30961 tccggttgct gatggtccag ttatcatgga agcaggtcaa caggcgatta aacaaggcat
    31021 cacgatagat tatattttca atcaattaga aaaacatggt gatcaaatta agtgtaacta
    31081 tgtattaatg acgtattata atattatttg tcattatgga gaacaagcgt tttttgaaaa
    31141 atgtcgagat actggtgtct acggcttaat tattcctgat ttaccatatg aattatcgca
    31201 gcgtttaaaa gaacaattta gtcactatgg cgtcaaaatc atatcgttag ttgcgatgac
    31261 tactgatgac aaacgtatga aagatatcgt atcccatgcg gaaggcttta tttatactgt
    31321 gacgatgaat gcgacaacag ggcaaaacgg tgcgtttcat ccagaattaa aacgaaaaat
    31381 tgagtcaatt aaagcgatag ccaatgtgcc agttgtcgca ggatttggta taagaacacc
    31441 tcaacatgtt gcagatataa aagaggttgc agatggcatc gtcattggta gcgaaatcgt
    31501 taagcgattt aaatctaaca cgcgtgaaga aatcattaaa tatttacaat ctatccaaca
    31561 aacattgaat aattaagttt acttgattta aaaaaattag tcgaatactg tttgaaaaag
    31621 tgaaaaacgg tgaattataa aattgaatag aaatgataca aaagtaatat gagcaaaccc
    31681 aaacgttcat attacttttt ttgaaattgt atgcaaaaat ctaaatatta ctataaaagt
    31741 atacgcaatt aaagcgttta tgttttagtt ttaacattaa ctattgtata cttatttaga
    31801 ttagatttat tatttttgac atttgcagag gggaaataga aaaactgcaa atacggaaat
    31861 gaaattaatt aacgagagac aaataggagt aatgataatg aagtttacaa atttaacagc
    31921 taaagagttt ggtgccttta cagatagcat gccatacagt catttcacgc aaactgttgg
    31981 ccactatgag ttaaaacttg ctgaaggtta tgaaacacat ttagtgggaa taaaaaacaa
    32041 taataacgag gttattgcag cttgcttact tactgctgta cctgttatga aagtgttcaa
    32101 gtatttttat tcaaatcgcg gtccagtgat cgattatgaa aatcaagaac tcgtacactt
    32161 tttctttaat gaattatcaa aatatgttaa aaaacatcgt tgtctatacc tacatatcga
    32221 tccatattta ccatatcaat acttgaatca tgatggcgag attacaggta atgctggtaa
    32281 tgattggttc tttgataaaa tgagtaactt aggatttgaa catactggat tccataaagg
    32341 atttgatcct gtgctacaaa ttcgttatca ctcagtgtta gatttaaaag ataaaacagc
    32401 agatgacatc attaaaaata tggatggact tagaaaaaga aacacgaaaa aagttaaaaa
    32461 gaatggtgtt aaagtaagat atttatctga agaagaactg ccaattttta gatcatttat
    32521 ggaagatacg tcagaatcaa aagcttttgc tgatcgtgat gacaaatttt actacaatcg
    32581 cttaaaatac tacaaagacc gtgtgttagt gcctttagcg tatatcaact ttgatgaata
    32641 tattaaagaa ctaaatgaag agcgtgatat tttaaataaa gatttaaata aagcattaaa
    32701 ggatattgaa aaacgtcctg aaaataaaaa agcgcataac aagcgagata acttacaaca
    32761 acaacttgat gcaaatgagc aaaagattga agaaggtaaa cgtctacaag aagaacatgg
    32821 taatgaatta cctatctctg ctggtttctt ctttatcaat ccatttgaag ttgtttatta
    32881 tgctggtggt acatcaaatg cattccgtca ttttgccgga agttatgcag tgcaatggga
    32941 aatgattaat tatgcattaa atcatggcat tgaccgttat aatttctatg gtgttagtgg
    33001 taaatttaca gaagatgctg aagatgctgg tgtagttaaa ttcaaaaaag gttacaatgc
    33061 tgaaattatt gaatatgttg gtgactttat taaaccaatt aataaacctg tttacgcagc
    33121 atataccgca cttaaaaaag ttaaagacag aattttttag gaagggaatt atcaaaacat
    33181 gaaatttaca gagttaactg ttaccgaatt tgacaacttt gtacaaaatc catcattgga
    33241 aagtcattat ttccaagtaa aagaaaatat agttacccgt gagaatgatg gctttgaagt
    33301 agttttatta ggtattaaag acgacaataa caaagtaatt gcagcaagcc ttttctctaa
    33361 aattcctact atgggaagtt atgtttacta ttcgaatcgt ggtccagtaa tggatttttc
    33421 agatttagga ttagttgatt attatttaaa agagttagat aaatatttac agcaacatca
    33481 atgtttatat gttaaattag atccgtattg gttatatcat ctatatgata aagatatcgt
    33541 gccatttgaa ggtcgcgaga aaaatgatgc cttagtaaac ttgtttaaat cacatggtta
    33601 cgagcatcat ggctttacaa ctgagtatga tacatcgagc caagtacgat ggttgggcgt
    33661 attaaacctt gaaggtaaaa cacccgaaac attgaaaaag acatttgata gtcaacgtaa
    33721 acgtaatatt aataaagcga taaactatgg tgttaaagtc agattccttg aacgtgatga
    33781 gttcaatctt ttcttagatt tatatcgtga aactgaagag cgtgctggat ttgtatcaaa
    33841 aacagatgat tatttttata actttattga cacatatgga gataaagtat tagtaccatt
    33901 agcatatatt gaccttgatg aatatgtgtt aaagttgcaa caggaattga atgacaaaga
    33961 aaatcgtcgt gatcaaatga tggcgaaaga aaacaaatca gataagcaaa tgaagaaaat
    34021 tgcagaatta gataagcaaa ttgatcatga tcagcatgaa ttattgaatg caagtgaatt
    34081 gagcaaaacg gacggcccaa ttctaaacct tgcttctggc gtttattttg caaatgcata
    34141 tgaagtgaat tatttctctg gtggttcatc agaaaaatat aatcaattta tgggaccata
    34201 catgatgcat tggtttatga ttaactattg cttcgataat ggttatgatc gttataattt
    34261 ctatggttta tcaggtgatt tcacagaaaa cagtgaagat tatggcgtat accgctttaa
    34321 acgtggattt aatgtacaaa tcgaagaatt aataggggat ttctataaac caattcataa
    34381 agtgaaatat tggttgttca caacattgga taaattacgt aaaaaattaa agaaatagat
    34441 gtaaatgatg ttagggctta tagttattga tgctataggc tcttttttat atgtttttta
    34501 gcgaaatttt aattatttca cactaagaaa aactagtatg tatttgtcaa tctaatgttt
    34561 ttcattat
//
LOCUS       DAPSKH010000030        33310 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPSKH010000030 DAPSKH010000000
VERSION     DAPSKH010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 33310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33310
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.030"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            258..1742
                     /locus_tag="RPH49_001429"
     CDS             258..1742
                     /locus_tag="RPH49_001429"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDY5124579.1"
                     /translation="MDASTLFKKVKVKRVLGSLEQQIDDITTDSRTAREGSIFVASVG
                     YTVDSHKFCQNVADQGCKLVVVNKEQSLPANVTQVVVPDTLRVASILAHTLYDYPSHQ
                     LVTFGVTGTNGKTSIATMIHLIQRKLQKNSAYLGTNGFQINETKTKGANTTPETVSLT
                     KKIKEAVDAGAESMTLEVSSHGLVLGRLRGVEFDVAIFSNLTQDHLDFHGTMEAYGHA
                     KSLLFSQLGEDLSKEKYVVLNNDDSFSEYLRTVTPYEVFSYGIDEEAQFMAKNIQESL
                     QGVSFDFVTPFGTYPVKSPYVGKFNISNIMAAMIAVWSKGTSLETIIKAVENLEPVEG
                     RLEVLDPSLPIDLIIDYAHTADGMNKLIDAVQPFVKQKLIFLVGMAGERDLTKTPEMG
                     RVACRADYVIFTPDNPANDDPKMLTAELAKGATHQNYIEFDDRAEGIKHAIDIAEPGD
                     TVVLASKGREPYQIMPGHIKVPHRDDLIGLEAAYKKFGGGPVDQ"
     gene            1723..1983
                     /locus_tag="RPH49_001430"
     CDS             1723..1983
                     /locus_tag="RPH49_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueH family protein"
                     /protein_id="HDY5124580.1"
                     /translation="MALLINKRFIDEGKTIDVYLFEALNNQIIIAIPDWFWSYQMAMT
                     LDEETCFEAILMQLFVFKEEEEAESIASQLTDWIETYKKEKD"
     gene            1983..3545
                     /locus_tag="RPH49_001431"
     CDS             1983..3545
                     /locus_tag="RPH49_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDY5124581.1"
                     /translation="MNLKQEVESRKTFAIISHPDAGKTTLTEKLLYFSGAIREAGTVK
                     GKKTGKFATSDWMKVEQERGISVTSSVMQFDYDDYKINILDTPGHEDFSEDTYRTLMA
                     VDSAVMVIDCAKGIEPQTLKLFKVCKMRGIPIFTFINKLDRVGKEPFELLDEIEETLN
                     IETYPMNWPIGMGQSFFGIIDRKSKTIEPFRDEENILHLNDDFELEEDHAITNDSAFE
                     QAIEELMLVEEAGEAFDNDALLSGDLTPVFFGSALANFGVQNFLNAYVDFAPMPNARQ
                     TKEDVEVSPFDDSFSGFIFKIQANMDPKHRDRIAFMRVVSGAFERGMDVTLQRTNKKQ
                     KITRSTSFMADDKETVNHAVAGDIIGLYDTGNYQIGDTLAGGKQTYSFQDLPQFTPEI
                     FMKVSAKNVMKQKHFHKGIEQLVQEGAIQYYKTLHTNQIILGAVGQLQFEVFEHRMKN
                     EYNVDVVMEPVGRKIARWIENEDQITDKMNTSRSILVKDRYDDLVFLFENEFATRWFE
                     EKFPEIKLYSLL"
     gene            3847..4650
                     /locus_tag="RPH49_001432"
     CDS             3847..4650
                     /locus_tag="RPH49_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDY5124582.1"
                     /translation="MLMDPSLILPYLWVLVVLVFLEGLLAADNAIVMAVMVKHLPPEQ
                     RKKALFYGLLGAFVFRFLALFLISIIANFWFIQAAGAVYLIYMSIKNLWQFFKHPEIE
                     SPEAGDDHHYDESGEEIKASNKSFWGTVLKIEFADIAFAIDSMLAALAIAVTLPKVGI
                     HFGGMDLGQFVVMFLGGMIGVILMRYAATWFVELLNKYPGLEGAAFAIVGWVGVKLVV
                     MVLAHPDIAVLPEHFPHGVLWQSIFWTVLIGLVIIGWLGSVVKNKKSHK"
     gene            4869..7193
                     /locus_tag="RPH49_001433"
     CDS             4869..7193
                     /locus_tag="RPH49_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDY5124583.1"
                     /translation="MEWTLVDIGKKHVIPKSQYRRKRREFFHNEDREENLKQHQDKQN
                     IDHTTSKKADKQIHKDSIDKHERFKNSLSSHLEQRNRDVNENKTEESKSNQDSKSAYS
                     RDHYLTDDVFKKQNSLDSVDQDTEKSKYYEQNSDATLSTKSTDKIESTDMRKLSSDKN
                     KVGHEEQHVLSKPSEHDKETRIDFESSRTDSDSSMQTEEIKKDSSDENKSSNLKSEVI
                     SDKSNTVPKLSESDDEVNNQKPLTLPEEQKLKRQQSQNEQTKTYTYGDSEQNDKSNHE
                     NDLSHHTPSISDDKDNVMRENHIVDDNPDNDINTPSLSKTDDDRKLDEKIHVEDKHKQ
                     NADSSETVGYQSQSSASHRSTEKRNISINDHDKLNGQKTNTKTSANNNQKKATSNLNK
                     GRATNNNYSDILKKFWMMYWPKLVILMGIIILIVILNAIFNNVNKNDRMNDNNDTDAQ
                     KYTTTMKNANNTVKSVVTVENETSKDSSLPKDKASQDEVGSGVVYKKSGDTLYIVTNA
                     HVVGDKENQKITFSNNKSVVGKVLGKDKWSDLAVVKATSSDSSVKEIAIGDSNNLVLG
                     EPILVVGNPLGVDFKGTVTEGIISGLNRNVPIDFDKDNKYDMLMKAFQIDASVNPGNS
                     GGAVVNREGKLIGVVAAKISMPNVENMSFAIPVNEVQKIVKGLETKGKIDYPDVGVKM
                     KNIASLNSFERQAVKLPGKVKNGVVVDQVDNNGLADQSGLKKGDVITELDGKLLEDDL
                     RFRQIIFSHKDDLKSITAKIYRDGKEKEINIKLK"
     gene            7210..8568
                     /locus_tag="RPH49_001434"
     CDS             7210..8568
                     /locus_tag="RPH49_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDY5124584.1"
                     /translation="MSIFSQFLKRSSPQQGIVLYYIVAIVIAFLLLNLPYVHKPGVEV
                     NPIDTLFVAVSGISVTGLSPISIVDTYSTFGQLIILVILNIGGIGVMAIGTMLWVVLG
                     KHIGIRERQLIMLDNNKNTMSGTVKLIIDIVKSIFVIELVGAMLLAFYFYRDNPDLKY
                     AIMQGVFVSISATTNGGLDITGKSLIPYAHDYFVQAIVIFLIILGSIGFPVLLEVKAY
                     IQNRVTNFRFSLFTKITTSTYLFLFIVGVLAILLFEHNHAFKGLSWHQSLFYSLFQSA
                     TTRSAGLQTIDVTTLSDPTNIIMGILMFIGSSPSSVGGGIRTTTFAILILFLINFSNN
                     ADKTSIKVYNREVHIMDIQRSFAVFTMATILTFLGMLIISATENGKLTFLQVFFEVMS
                     AFGTCGLSLGVTSDISDISKVVLMVLMFIGRVGLISFIIMIAGRREPDKFHYPKERIQ
                     IG"
     gene            8707..10218
                     /locus_tag="RPH49_001435"
     CDS             8707..10218
                     /locus_tag="RPH49_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDY5124585.1"
                     /translation="MEKNENINVEILTTSDMHSHFLNGDYGSNIYRAGTYVNQVRAQN
                     HRVILLDSGGSLAGSLAAYYYAIVAPYKRHPMIKLMNRMHYDASGVSPSEFKFGLSFL
                     TRSIALARFPWLSANIEYNVTKEPYFSTPYCIKHFGDLKIAIVGVTADGLMENEYSEM
                     EQDVSIEKTLVASKRWIRYIHEVEEPDFLIVIYHGGLNKISNSTKNKKASSNEAEKLM
                     EELGVIDLMITAHQHQTIVGQDHETYYVQAGQDAKELVHLSINFKKRTTTYDVESIDS
                     KVIDLNEYEEDQELLDLTFYDRKAVAYWSQEIISDKGLMLSVNGLQDLVCQTHPFSQL
                     LHDAIHLAFDNDITCVHVPMNGEKGLSGQIRNEDLYHAYPYPDKPMDMTISGQNIKDI
                     LEYSYSHLDFVNEQLSLTIIDETLCTMWQGFNYEIDMNQEPGQRVMLDQIDLTKSYRV
                     TMTDYCYRNYKNYLKNAIIHESYDETMSTLIAEKLRDPNYRISCSDNFVVKNR"
     gene            complement(10400..10488)
                     /locus_tag="RPH49_001436"
     tRNA            complement(10400..10488)
                     /locus_tag="RPH49_001436"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10451..10453),aa:Ser,seq:gct)
     gene            complement(10491..10565)
                     /locus_tag="RPH49_001437"
     tRNA            complement(10491..10565)
                     /locus_tag="RPH49_001437"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10531..10533),aa:Asn,seq:gtt)
     gene            complement(10707..11276)
                     /locus_tag="RPH49_001438"
     CDS             complement(10707..11276)
                     /locus_tag="RPH49_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComK"
                     /protein_id="HDY5124586.1"
                     /translation="MYSQNIYVIRKGDMVIRPAFDDDDQRNGSEIIRFDKTRIQNPFK
                     VQKIIERSCKFYGNTYLGKKAETNRITGISSKPPILLTPLFPTYFFPTHSDRQNENIW
                     LNMHYIESIKELKNRKCKVTFINNESIILHVSYHSLWHQYNNSIFYYYMVDKQSRMIS
                     KNPDQPIDYNKATLNVFEALTRYSLFEDK"
     gene            11486..11704
                     /locus_tag="RPH49_001439"
     CDS             11486..11704
                     /locus_tag="RPH49_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IDEAL domain-containing protein"
                     /protein_id="HDY5124587.1"
                     /translation="MKYNTNVKHTTLEAFVTTVNDLGIELIINEALREVRKRQLIELI
                     DDALVNKDEAAFNQYTAEYKNLEAFLGE"
     gene            complement(11785..12771)
                     /locus_tag="RPH49_001440"
     CDS             complement(11785..12771)
                     /locus_tag="RPH49_001440"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDY5124588.1"
                     /translation="MKFISNNNITDPTLNLAMEEYVLKNLPAEESYFLFYINRPSIIV
                     GKNQNTIEEVNQTYIDAHNIDVVRRISGGGAVYHDTGNLNFSFITDDDGNSFHNFQKF
                     TEPIVQALQSLGVNAELTGRNDIQVGQAKISGNAMVKVKNRMFSHGTLMLNSDLDEVQ
                     NALKVNPAKIKSKGIKSVRKRVANIQEFLNDPLEIEEFKKIILKTIFGETEVEEYKLT
                     DEDWENIEKLSNDKYRTWEWNYGRNPKYNFEREEKFEKGFVQIKFDVKRGKIEHAKIF
                     GDFFGVGDVTDLENALVGCLHDFEHIEEALSEYDLYHYFGDIVRHELIRLMS"
     gene            12970..13146
                     /locus_tag="RPH49_001441"
     CDS             12970..13146
                     /locus_tag="RPH49_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkvS family protein"
                     /protein_id="HDY5124589.1"
                     /translation="MTVAEVGNIVEFMDGLRGRVEKINDNSVIVDLTIMENFNDLDLP
                     EKTVINHKRYKIVE"
     gene            13161..13763
                     /locus_tag="RPH49_001442"
     CDS             13161..13763
                     /locus_tag="RPH49_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDY5124590.1"
                     /translation="MNKISKALTWFIISFIIFHLILFIMWGEHQEYWYLYTGIMLIAG
                     ISYVFYQRDIESKRLLTSIGVGIITAIILIMLQLLFSLITSNLSYSSLIKELARTGVN
                     WKWQMLVTLLFVIPCHELYMRTVLQKELTHFSIPKWVAILITAICSSSLFIYLDNWWI
                     VTFIFVAQVILSLSYEYTRRIATTSVAQIVAIILLLIFNA"
     gene            13873..14060
                     /locus_tag="RPH49_001443"
                     /pseudo
     CDS             13873..14060
                     /locus_tag="RPH49_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500662.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
     gene            14707..14979
                     /locus_tag="RPH49_001444"
     CDS             14707..14979
                     /locus_tag="RPH49_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001790097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HDY5124591.1"
                     /translation="MFGTILYLTLALGLSTAAYASTEYAEGGTWSHGVGSKYVWSYYY
                     HGHKGHGATAIGKYRSFSGYTRAGVKAKGSATKHNCWINRAYYNIY"
     gene            15023..16987
                     /locus_tag="RPH49_001445"
     CDS             15023..16987
                     /locus_tag="RPH49_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HDY5124592.1"
                     /translation="MKWFKLILDVTIFILIAILLFVYTYKENEEILPDTKYPIAVTDW
                     NKKYSKNEIYKHINQFAKNENVAIYKSTSNYTNKNVDKDIYVFNKSKATTITPFNAKY
                     NIHYLSDDEVLKKDIKGSYFVKDKNFDVSKFINFLKEYGVTAESYKIDHMMIAVGVIK
                     QMNIVVPLSSLLIVYFIYYIFEKNINFKAYAIKYLNGFTLRKIIFENFSKKCTYWVTL
                     IITQILLTTSVLWILNYTGNLDLFILRIVLLSCLFILTISVINLWTFLMLLNLNIANM
                     IKGKQHFKTIRFINTVCKSILLVLIANVMIENTSVIKDLNKIKETEKYWNVLDDYYTI
                     EFAPYHETKQSLIDNMVRSEQLVKASEAENNAILFKPKGDSVDNDNFSPDEGNVILVN
                     NQFWSIYHKQFQPDIPIKNQKNNVEVIIPQKFHAMRNEINQAYHSWFEFVHNKNNKES
                     KLSIQFINKNDYRIFTFDARDSRHLSFIEAPIIVNVQASDLSNDFYYAMISQGGYLFK
                     NYDALVKNIEKYHLDGEISGITNYKDSVMEMYHENNLKLTVLNFSQIIIAIILIIIIL
                     FDVKYYFEQHRKLLVIKKLYGYSTLRANYQYLLINNIVVVFIGILTNVILHSQYIMMI
                     FVTIIVVQILLQICSLYYHGRRFNGVIKEF"
     gene            16990..17310
                     /locus_tag="RPH49_001446"
     CDS             16990..17310
                     /locus_tag="RPH49_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDY5124593.1"
                     /translation="MKFIIAILLGLILSITIAFTIIHHPILDRFNPFLKTEYSYAKVP
                     KGTQQYVNITAYSERGEKLDYKLTFNGFSPSRTYVEIKHKGQYVISITYVEKEDTPKE
                     VRQE"
     gene            17307..17948
                     /locus_tag="RPH49_001447"
     CDS             17307..17948
                     /locus_tag="RPH49_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124594.1"
                     /translation="MIELKDLTIQKGNTHILKKLNLKFQCGKSYALIGKSGCGKSTLL
                     NTIAGLEKTGKQYVYFNGQLEQFKSNFYRDKLGYLFQNYGLIDNLTVNENLDIGLAYK
                     KISKKEKEQLKIRYIEQFGLSNSLKRKVHTLSGGEQQRVALIRMMLKDPIVMLADEPT
                     GALDPKTGQMIIQSLFDLVDENKVLILATHDMAIANQCDEIIDLEQYRKVASM"
     gene            complement(18036..18326)
                     /locus_tag="RPH49_001448"
     CDS             complement(18036..18326)
                     /locus_tag="RPH49_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124595.1"
                     /translation="MFCAYHFKMKIGGVILTRTYNIIGILSCLISFIIMALPMIWYTA
                     SALWFFPGAIMILLLSLVIVFCYIKTKNQLHLLLLVLNIIILLFFSLPLLLS"
     gene            18467..18604
                     /locus_tag="RPH49_001449"
     CDS             18467..18604
                     /locus_tag="RPH49_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001788572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly(glycerol-phosphate)
                     alpha-glucosyltransferase"
                     /protein_id="HDY5124596.1"
                     /translation="MADKILKLVNNDVLAEEFGSKARENIIEKYSTESTLEKWLNLFN
                     S"
     gene            complement(18693..19049)
                     /locus_tag="RPH49_001450"
     CDS             complement(18693..19049)
                     /locus_tag="RPH49_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDY5124597.1"
                     /translation="MKLGMLLIRWMLATSFLVHGTLKFVDLDGTIHFLGSLGLPPTIA
                     VLMSIGEVVGGLALIIGFLTPYVNVFYICVMLGSIFTLKLTRGYVSGYEFEIIHIVMN
                     LACISSYSWKKWLQFY"
     gene            19540..20497
                     /locus_tag="RPH49_001451"
                     /pseudo
     CDS             19540..20497
                     /locus_tag="RPH49_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081330.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(20543..20674)
                     /locus_tag="RPH49_001452"
     CDS             complement(20543..20674)
                     /locus_tag="RPH49_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124598.1"
                     /translation="MRYVTMRQFIKRIVKTILVGYVLKFIRNKLSGKSSHSTNNKHN"
     gene            complement(20738..20953)
                     /locus_tag="RPH49_001453"
     CDS             complement(20738..20953)
                     /locus_tag="RPH49_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TM2 domain-containing protein"
                     /protein_id="HDY5124599.1"
                     /translation="MKVNKAIYVIVALFLGGLGIHKFYADKFGQGLFHLLFFWTGIPT
                     IISIIHAIFVIFTKKADRDGYIIFPKN"
     gene            21118..21669
                     /locus_tag="RPH49_001454"
     CDS             21118..21669
                     /locus_tag="RPH49_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124600.1"
                     /translation="MIRQARPEDRFDIAKLVYMVWDDMELELVKHLPKDMVLDAIEKS
                     CVDATYRTFYQHILVYEVENKVAGCIISYSGENELKYEKAWALLDLPEEIKQYGTPLP
                     VKEAKDDEYYIETIATFAAYRGRGIATKLLTSLLESNTHVKWSLNCDINNEAALKLYQ
                     KVGFISDGQIELYKHMYHHLIVK"
     gene            complement(21721..22659)
                     /locus_tag="RPH49_001455"
     CDS             complement(21721..22659)
                     /locus_tag="RPH49_001455"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDY5124601.1"
                     /translation="MSNQYQQYSTVKKYWHLMRPHTLTASVVPVLVGTAASKIYFLGS
                     EDHIKISLFIAMLLACLLIQAATNMFNEYYDYKKGLDDHESVGIGGAIVRNGMSPELV
                     LRLAIAFYILAAILGLFLAANSSFWLLPVGLVCMAVGYLYTGGPFPISWTPFGELFSG
                     VFMGMFIIVIAFFIQTGNIQSYVIWLSVPIVITIGLINMANNIRDRVKDKASGRKTLP
                     ILLGKNASLTFMAIMYFIAYAFIVLTIIIKPGGSLFYLLALLSFPMPVKVIRRFKKND
                     TPPTMMPAMAAAGKTNTFFGLLYALGIYISALFAGI"
     gene            22841..24202
                     /locus_tag="RPH49_001456"
     CDS             22841..24202
                     /locus_tag="RPH49_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000190617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDY5124602.1"
                     /translation="MATGVLEDDIVKEIYDSSKEWVSVEVKLSQSLDPSTLFHLTDNE
                     AGDRFYMRLNDNRTSYFGYKANQLFKNNSKNKQSIFKDWEKLKHNITFIHPQSEKHHL
                     RVVGGFQFSSHKSDDEWREFGLNHFVLPEVLISTDNNGTFLTYTVKRESFTVEALNDL
                     MDLFNNISDIDVDEQIGEITRNEDIYKDDWRQLVVEAIESINNEEKIVLARRRLIKFD
                     KDISIPYILKQAYSKEKNSYIFLLESQDSIFFSQTPEQLIKVNNKILSTKAVAGTIKR
                     SQDEDEDTKNVDAFLKDNKNLIEHRFVVDSILHDIKPYITELHYDKTPKILKNDHLYH
                     LYTEIKAPLKDDSYISLIDHLHPTPALGGYPKEFAMDFIEQKEFGTRGLYGAPVGYID
                     IYDDCEFIVAIRSMLIKKAQATLFAGCGIVKDSDPDSELAETNLKFTPMMNALGVDMN
                     GKS"
     gene            24189..25862
                     /gene="menD"
                     /locus_tag="RPH49_001457"
     CDS             24189..25862
                     /gene="menD"
                     /locus_tag="RPH49_001457"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDY5124603.1"
                     /translation="MGNHKAALTKQVFTFASELYAYGVREVVISPGSRSTPLALAFEA
                     HPNIKTWIHPDERSAAFFAVGLIKGSERPVAILCTSGTAAANYTPAIAESQISRIPLI
                     VLTSDRPHELRSVGAPQAINQVNMFNNYVSYEFDMPIADDSKETIDAIYYQMQIASQY
                     LYGPHKGPIHFNLPFRDPLTPDLNATELLTSEMKILPHYQKSIDASALRHILNKKKGL
                     IIVGDMQHQEVDQILTYSTIYDLPILADPLSHLRKFDHPNVICTYDLLFRSGLDLNVD
                     FVIRVGKPVISKKLNQWLKKTDAFQILVQNNDKIDVFPIAPDISYEISANDFFRSLME
                     DTTINRVSWLEKWQRLEKKGRKEIKCYLEQATDESAFVGELIKKTSEKDALFISNSMP
                     IRDVDNLLLNKNIDVYANRGANGIDGIVSTALGMAVHKRITLLIGDLSFYHDMNGLLM
                     SKLNNIQMNIVLLNNDGGGIFSYLPQKESATDYFERLFGTPTGLDFEYTAKLYQFDFK
                     RFNSVSEFKNATLLSETSTIYELITNREDNFKQHQILYQKLSEMIHDTL"
     gene            25849..26652
                     /gene="menH"
                     /locus_tag="RPH49_001458"
     CDS             25849..26652
                     /gene="menH"
                     /locus_tag="RPH49_001458"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDY5124604.1"
                     /translation="MTHYNYYEANVETNQVLVLLHGFLSDSRTYHNHIDKYTDICHVI
                     TIDLPGHGEDQSSMDETWNFDYITTLLDRILDKYKDKSITLFGYSMGGRVALYYAING
                     HIPISNLILESTSPGIKEEANQLERRLVDDARAKVLDIAGIELFVNDWEKLPLFQSQL
                     ELPVEIQHQIRQQRLSQSPHKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGECDEK
                     FVQIAKKMANLIPNSKCKLISDTGHTIHVEDSDEFDTMILGFLKEEQND"
     gene            26645..27466
                     /gene="menB"
                     /locus_tag="RPH49_001459"
     CDS             26645..27466
                     /gene="menB"
                     /locus_tag="RPH49_001459"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDY5124605.1"
                     /translation="MTNRQWETLREYDEIKYEFYEGIAKVTINRPEVRNAFTPKTVAE
                     MIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRL
                     IRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLA
                     RIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALR
                     FLKAAMNADTDGLAGLQQMAGDATLLYYTTDEAKEGRDAFKEKRDPDFDQFPKFP"
     gene            complement(27704..28033)
                     /gene="sspC"
                     /locus_tag="RPH49_001460"
     CDS             complement(27704..28033)
                     /gene="sspC"
                     /locus_tag="RPH49_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphostatin B"
                     /protein_id="HDY5124606.1"
                     /translation="MYQLQFINLVYDTTKLTHLEQTNINLFIGNWSNHQLQKSICIRH
                     GDDTSHNQYHILFIDTAHQRIKFSSIDNEEIIYILDYDDTQHILMQTSSKQGIGTSRP
                     IVYERLV"
     gene            complement(28071..29252)
                     /gene="sspB"
                     /locus_tag="RPH49_001461"
     CDS             complement(28071..29252)
                     /gene="sspB"
                     /locus_tag="RPH49_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease staphopain B"
                     /protein_id="HDY5124607.1"
                     /translation="MNSSYKSRVFNIISIIMVSMLILSLGAFANNNKAKADSHSKQLE
                     INVKSDKVPQKVKDLAQQQFAGYAKALDKQSNAKTGKYELGEAFKIYKFNGEEDNSYY
                     YPVIKDGKIVYTLTLSPKNKDDLNKSKEDMNYSVKISNFIAKDLDQIKDKNSNITVLT
                     DEKGFYFEEDGKVRLVKATPLPGNVKEKESAKTVSAKLKQELKNTVTPTKVEENEAIQ
                     EDQVQYENTLKNFKIREQQFDNSWCAGFSMAALLNATKNTDTYNAHDIMRTLYPEVSE
                     QDLPNCSTFPNQMIEYGKSQGRDIHYQEGVPSYEQVDQLTKDNVGIMILAQSVSQNPN
                     DPHLGHALAVVGNAKINDQEKLIYWNPWDTELSIQDADSSLLHLSFNRDYNWYGSMIG
                     Y"
     gene            complement(29334..30398)
                     /gene="sspA"
                     /locus_tag="RPH49_001462"
     CDS             complement(29334..30398)
                     /gene="sspA"
                     /locus_tag="RPH49_001462"
                     /EC_number="3.4.21.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Glu-specific serine endopeptidase SspA"
                     /protein_id="HDY5124608.1"
                     /translation="MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQT
                     DKQQTPKIQKGGNLKPLEQRERANVILPNNDRHQITDTTNGHYAPVTYIQVEAPTGTF
                     IASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG
                     DLAIVKFSPNEQNKHIGEVVKPATMSNNDETQVNQNITVTGYPGDKPVATMWESKGKI
                     TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQ
                     NIEDIHFANDDQPNNPDNPDNPNNPDEPNNPDNPNNPDNPNNPDNPNNPDNPNNPDNP
                     NNPDNPDNGDNNNSDNPDAA"
     gene            complement(30926..32080)
                     /locus_tag="RPH49_001463"
     CDS             complement(30926..32080)
                     /locus_tag="RPH49_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDY5124609.1"
                     /translation="MKLSLNSNSKYLRAPSIRQFSNRMKGLDDCVNLTIGQPDFPMPD
                     VVKRAYIDAINNNQTSYSHNKGLLETREAISQYFKNRYHFYYDPEEIIVTNGASEAID
                     TTLRSIIEPGDEIIIPGPIYAGYIPLIEVLGGKPIYIDTTATQFKITPDALESHISPK
                     TKAVLLNYPTNPTGVVLKRNEVLNIVNVLKKYPIFIISDEIYAENTFSGKHVSFAEFE
                     DIRDQLILIGGLSKSHSATGIRIGFLLGPQYLIEKLTFMHAYNCICANVPAQIACITA
                     LNEGLEAPKYMNEAYVERRNYLVSELTKLGFEITAQPEGAFYIFPSIKHITDDDFEFC
                     VDLLESTHLAIVPGSSFTEFGKGFVRISYAYEMDVLKEGMKRLAKYLNTK"
     gene            complement(32276..33286)
                     /locus_tag="RPH49_001464"
     CDS             complement(32276..33286)
                     /locus_tag="RPH49_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDY5124610.1"
                     /translation="MTSLKERDYFFDNARAILILLVVFGHMLQPYTSGDKYLSALYLV
                     IYSFHMPTFLFISGYFAKNIDKPYYLEKISKRLIVPYMIFFAFFSIYYFLTGKSDELQ
                     LDPFNPVFALWFLITLFFFHVILVIVRRFNPYKVLSVSIIISIGAGFSGNIDSYLSIS
                     RTIVFFPIFYLGYIFTKKHTAIFKNKKLIPVSIITFILFFIIYVIHPINADWLLGSSP
                     YTSLENEGQSVFSPFKRLILYGIILIAMTAFLNLISTKKKLYTYIGSRTLYVYLLHGL
                     IIGIVRGFEWYPFDNPISLMTYLYLISISVIIVYVLSTNFVCKWTNPIINLQRPSQFK
                     DS"
BASE COUNT        11932 a         4554 c         5847 g        10977 t
ORIGIN      
        1 gtatatttaa aattatccag tatacaatta tagcatattt ttggaaacaa ttatgatatt
       61 ataccatgtt acaagatggt tttaataatt taagatgagc cataattgta aaactaattc
      121 ataataccgt atgttttatt tttaatagta gaaattagaa aatgctgatt agtaggatat
      181 aacagtgaaa ttataaattt attaacatca acaaaacgtg tataataaac atattgtaga
      241 aaaaggagcg gttcagtttg gatgcaagta cgttgtttaa gaaagtaaaa gtaaagcgtg
      301 tattgggttc tttagaacaa caaatagatg atatcactac tgattcacgt acagcgagag
      361 aaggtagcat ttttgtcgct tcagttggat atactgtaga cagtcataag ttctgtcaaa
      421 atgtagctga tcaagggtgt aagttggtag tggtcaataa agaacaatca ttaccagcta
      481 acgtaacaca agtggttgtg ccggacacat taagagtagc tagtattcta gcacacacat
      541 tatatgatta tccgagtcat cagttagtga catttggtgt aacgggtaca aatggtaaaa
      601 cttctattgc gacgatgatt catttaattc aaagaaagtt acaaaaaaat agtgcatatt
      661 taggaactaa tggtttccaa attaatgaaa caaagacaaa aggtgcaaat acgacaccag
      721 aaacagtttc tttaactaag aaaattaaag aagcagttga tgcaggcgct gaatctatga
      781 cattagaagt atcaagccat ggcttagtat taggacgact gcgaggcgtt gaatttgacg
      841 ttgcaatatt ttcaaattta acacaagacc atttagattt tcatggcaca atggaagcat
      901 acggacacgc gaagtcttta ttgtttagtc aattaggtga agatttgtcg aaagaaaagt
      961 atgtcgtgtt aaacaatgac gattcatttt ctgagtattt aagaacagtg acgccttatg
     1021 aagtatttag ttatggaatt gatgaggaag cccaatttat ggctaaaaat attcaagaat
     1081 ctttacaagg tgtcagcttt gattttgtaa cgccttttgg aacttaccca gtaaaatcgc
     1141 cttatgttgg taagtttaat atttctaata ttatggcggc aatgattgcg gtgtggagta
     1201 aaggtacatc tttagaaacg attattaaag ctgttgaaaa tttagaacct gttgaagggc
     1261 gattagaagt tttagatcct tcgttaccta ttgatttaat tatcgattat gcacatacag
     1321 ctgatggtat gaacaaatta atcgatgcag tacagccttt tgtaaagcaa aagttgatat
     1381 ttttagttgg tatggcaggc gaacgtgatt taactaaaac gcctgaaatg gggcgagttg
     1441 cctgtcgtgc agattatgtc attttcacac cggataatcc ggcaaatgat gacccgaaaa
     1501 tgttaacggc agaattagcc aaaggtgcaa cacatcaaaa ctatattgaa tttgatgatc
     1561 gtgcagaagg gataaaacat gcaattgaca tagctgagcc tggggatact gtcgttttag
     1621 catcaaaagg aagagaacca tatcaaatca tgccagggca tattaaggtg ccacatcgag
     1681 atgatttaat tggccttgaa gcagcttaca aaaagttcgg tggtggccct gttgatcaat
     1741 aaaagattta ttgatgaagg taaaactatt gatgtttatt tattcgaagc attaaataac
     1801 cagataatca ttgctatacc agattggttt tggtcatatc agatggcaat gacattagat
     1861 gaagaaactt gttttgaagc aatactcatg caattgtttg tttttaaaga agaggaagag
     1921 gcagaatcga ttgcatcaca actaacagat tggatagaaa catataaaaa ggagaaagac
     1981 taatgaactt aaagcaagaa gttgagtcta gaaagacttt tgcgattatt tcacatcccg
     2041 atgcagggaa aacaacgtta actgaaaaac tattgtactt cagtggtgct attcgtgaag
     2101 cgggtacagt taaagggaag aagactggta aatttgcgac aagtgactgg atgaaagttg
     2161 aacaagagcg tggtatttct gtaactagtt cagtaatgca atttgattac gatgattata
     2221 aaatcaatat cttagataca ccaggacatg aagacttttc agaagatacg tatagaacat
     2281 taatggcagt tgacagtgct gtcatggtca tagactgtgc aaaaggtatt gaaccacaaa
     2341 cattgaagtt atttaaagtt tgtaaaatgc gtggtattcc aatctttaca ttcattaata
     2401 aattagaccg agtaggtaaa gaaccatttg aattattaga tgaaatcgaa gagacattaa
     2461 atattgaaac ataccctatg aattggccaa ttggtatggg acaaagtttc tttggcatca
     2521 ttgatagaaa gtctaaaaca attgaaccat ttagagatga agaaaatata ttacatttga
     2581 atgatgattt tgagttggaa gaagatcatg caattacaaa tgatagtgct tttgaacaag
     2641 cgattgaaga attaatgttg gttgaagaag cgggtgaagc ctttgataat gacgcgctgt
     2701 tgagtggaga cttaacacct gtatttttcg gttcagcttt agctaacttt ggtgtacaaa
     2761 atttcttaaa tgcatatgtt gattttgcgc caatgccaaa tgcgagacaa acaaaagaag
     2821 acgttgaagt aagcccgttt gatgattcat tttcaggatt tatctttaaa attcaagcca
     2881 acatggaccc taaacaccgt gatagaattg cctttatgcg tgtcgttagt ggtgcatttg
     2941 aacgtggtat ggatgttact ttgcaacgta ctaataaaaa gcaaaagatc acacgttcaa
     3001 cgtcatttat ggcagacgat aaagaaactg tgaatcatgc tgtagcaggc gatatcattg
     3061 gactatatga tactggtaat tatcaaattg gagatacttt agctggtgga aaacaaacct
     3121 acagtttcca agatttacca caatttacgc cagaaatttt tatgaaagtt tctgctaaaa
     3181 acgtcatgaa acagaagcat ttccataaag gtattgaaca attagtacaa gaaggtgcga
     3241 ttcaatacta taaaacatta cacacaaacc aaattatttt aggtgctgtt ggtcagttac
     3301 aatttgaagt tttcgaacat agaatgaaaa acgaatataa tgttgatgtt gttatggagc
     3361 cagtaggccg taaaattgca cgttggattg aaaatgaaga ccaaattaca gataagatga
     3421 acacatcaag atcgatttta gtgaaagata gatatgacga tttagtattc ttatttgaaa
     3481 atgaatttgc aacaagatgg tttgaagaga aattccctga aattaaattg tatagtttac
     3541 tttaacagct caattgtata atcgaatttg ttacattaaa aataattgtt tcgttgaaga
     3601 aaaataaatt gtatatttta aaagaaaaag gtatactatg atgtatcaaa tgaataacct
     3661 atggcatttt gtcagagggg agtaacttaa gaatcatgac cgtataaatg attcgacact
     3721 ttatcgtcat tacgaagata tcttccggta aagtgggcaa tttaaattgc ttagtgagac
     3781 ctttgctatt tatttagcat aggtcttttt gtttgtactt aacttattta tttaaaggag
     3841 ttgtacatgt taatggatcc aagtttgatc ttaccttatt tatgggtact tgtcgtttta
     3901 gtatttttag aaggcttatt agcagcagat aacgcgattg ttatggctgt aatggttaag
     3961 cacttaccac ccgaacaacg taaaaaagct ttgttttacg gtttgttagg tgcatttgta
     4021 tttagatttt tagcattatt cttaattagt attatcgcga acttttggtt tattcaagct
     4081 gcaggagcgg tttacttaat ttatatgtca atcaaaaatc tgtggcagtt ctttaaacac
     4141 ccagaaattg aaagtcctga agctggagat gatcatcatt atgatgaatc tggtgaagag
     4201 attaaagcaa gtaacaaatc attctgggga actgtgttga aaatagaatt tgcagatatc
     4261 gcatttgcca tagattctat gcttgctgct ttagctattg ctgtaacact tcctaaagtt
     4321 ggtattcact ttggtggtat ggacttaggt cagttcgtag tcatgttcct aggtggaatg
     4381 attggtgtta ttctaatgcg ttatgcagca acatggtttg tagagctatt aaacaaatat
     4441 ccaggacttg aaggtgcagc cttcgcgatc gttggttggg taggtgttaa attagttgtc
     4501 atggtattag cgcacccaga catcgctgta ttgcctgagc acttcccaca tggcgtatta
     4561 tggcaatcta ttttctggac agtactaatt ggattagtaa ttatcggttg gttaggttca
     4621 gttgttaaaa ataaaaaatc gcataaataa ttgatgtgaa gcggacaatc ttaatttagt
     4681 ttaaggttgt cctttttcat ttaattgagt gatttatgaa aaatggattt tgaagaatat
     4741 gaatcaaaat atgcgatata gcattaagaa aatgtgcctt ttatatttag cattttttca
     4801 atagaaatta tatagatttt aaagcaaatt aagtgttaat gtgtcataat gaaaagtgat
     4861 tttattgaat ggagtggaca ttagtggata ttggtaaaaa acatgtaatt cctaaaagtc
     4921 agtaccgacg taagcgtcgt gaattcttcc acaacgaaga cagagaagaa aatttaaaac
     4981 aacatcaaga taaacaaaat atagatcata caacatcaaa aaaagcagat aagcaaatac
     5041 ataaagattc aattgataag cacgaacgtt ttaaaaacag tttatcatcg catttagaac
     5101 agagaaaccg tgatgttaat gagaataaaa ctgaagaaag taaaagtaat caggatagta
     5161 agtcagcata tagcagagat cattatttaa cagacgatgt atttaaaaaa caaaattcat
     5221 tagattcagt ggaccaagat acagagaaat caaaatatta tgagcaaaat tctgatgcga
     5281 ctttatcaac taaatcaacc gataaaatag aatcaactga catgagaaag ctaagttcag
     5341 ataaaaacaa agttggtcat gaagagcaac atgtactttc taaaccttca gaacatgata
     5401 aagagactag aattgatttt gagtcttcaa gaactgattc agacagctcg atgcagacag
     5461 aggaaataaa aaaagacagt tcagatgaaa ataaaagtag taatctgaaa tctgaagtaa
     5521 tatcagacaa atcaaataca gtaccaaaat tgtcggaatc tgatgatgaa gtaaataatc
     5581 agaagccatt aactttgccg gaagaacaga aattgaaaag acagcaaagt caaaatgagc
     5641 aaacaaaaac ctatacatat ggtgatagcg aacaaaatga caagtctaat catgaaaatg
     5701 atttaagtca tcatacacca tcgataagtg atgataaaga taacgttatg agagaaaatc
     5761 atattgttga cgataatcct gataatgata tcaatacacc atcattatca aaaacagatg
     5821 acgatcgaaa acttgatgaa aaaattcatg ttgaagataa acataaacaa aatgcagact
     5881 cgtctgaaac ggtgggatat caaagtcagt caagtgcatc tcatcgtagc actgaaaaaa
     5941 gaaatatttc tattaatgac catgataaat taaacggtca aaaaacaaat acaaagacat
     6001 cggcaaataa taatcaaaaa aaggctacat caaatttgaa caaagggcgc gctacaaata
     6061 ataattatag tgacattttg aaaaagtttt ggatgatgta ttggcctaaa ttagttattc
     6121 taatgggtat tattattcta attgttattt tgaatgccat ttttaataat gtgaataaaa
     6181 atgatcgcat gaatgataat aatgatacag atgctcaaaa atatacgaca acgatgaaaa
     6241 atgccaataa cacagttaaa tcggtcgtta cagttgaaaa tgaaacatca aaagattcat
     6301 cattacctaa agataaagca tctcaagacg aagtaggatc aggtgttgta tataaaaaat
     6361 ctggagatac gttatatatt gttacgaatg cacacgttgt cggtgataaa gaaaatcaaa
     6421 aaataacttt ctcgaataat aaaagtgttg ttgggaaagt gcttggtaaa gataaatggt
     6481 cagatttagc tgttgttaaa gcaacttctt cagacagttc agtgaaagag atagctattg
     6541 gagattcaaa taatttagtg ttaggagagc caatattagt cgtaggtaat ccacttggtg
     6601 tagactttaa aggcactgtg actgaaggta ttatttcagg tctgaacaga aatgttccta
     6661 ttgatttcga taaagataat aaatatgata tgttgatgaa agctttccaa attgatgcat
     6721 cagtaaatcc aggtaactcg ggtggtgctg tcgtcaatag agaaggaaaa ttaattggtg
     6781 tagttgcagc taaaattagt atgccaaacg ttgaaaacat gtcatttgca atacctgtta
     6841 atgaagtaca aaagattgta aaaggtttag aaacaaaagg taaaattgac tatcccgatg
     6901 taggtgttaa aatgaagaat attgccagtc taaatagttt tgaaagacaa gcagttaaat
     6961 tgccaggaaa agttaagaac ggtgttgttg tagatcaagt tgacaacaat ggtttagcgg
     7021 atcaatctgg tctgaaaaaa ggtgatgtaa ttacagaatt agatggcaaa cttttagaag
     7081 atgatttacg ctttaggcag attatattta gtcataaaga tgacttgaaa tcaattacag
     7141 cgaagattta tagagatggt aaagagaaag aaattaatat taaactaaaa taatgttgag
     7201 gtgaacaacg tgtcaatttt tagccagttt ttaaaaagat caagccctca acaaggtatt
     7261 gtattgtact atatcgtcgc aattgtcatt gcatttttat tattaaactt accgtatgtt
     7321 cataaaccag gtgtagaagt aaatccaatt gacacattat ttgttgccgt atccggaatt
     7381 agtgttactg gattgtctcc gataagtatt gtcgatacct attctacatt tggacaatta
     7441 attatcctcg tgatattaaa tattggtgga attggcgtca tggcaattgg tacgatgtta
     7501 tgggtggtac taggtaaaca tattggaatt agagaacgtc agttaattat gttagataat
     7561 aacaaaaaca caatgagtgg taccgtcaaa ttgattattg atattgtaaa atcaatattt
     7621 gtaatcgaac tcgtaggagc catgttatta gcattttact tttatcgaga taatccagat
     7681 ttaaaatatg caatcatgca aggtgttttt gtttctattt ctgccactac caatggtgga
     7741 ttagatatta caggtaagtc attaattcct tatgcacatg attattttgt acaagcgata
     7801 gttatatttt taataatttt aggatcaatc ggcttcccag tattattaga agttaaagct
     7861 tatattcaaa atagggttac taattttaga ttttcattat ttactaaaat tacgacatca
     7921 acatatttat ttttatttat tgttggggta ttagccattc tattatttga acataaccat
     7981 gcgttcaaag gattaagttg gcatcaatcg ttattctatt cgctatttca atcagcgact
     8041 acaagaagtg cgggtcttca aacaattgat gtgacaacac taagtgaccc tacgaatatt
     8101 atcatgggta ttttaatgtt tataggttct tcgccaagtt cggttggtgg cggtattcgt
     8161 acaacaacat tcgctatttt aattttgttt ttaattaact ttagtaataa tgccgataaa
     8221 acatccatta aagtttacaa tagagaagta cacattatgg atattcaacg ttcatttgca
     8281 gtatttacaa tggcgacaat tttaacattt ttaggaatgc taattatatc agctactgaa
     8341 aatggtaagc ttacattttt acaagtattt tttgaagtca tgtctgcatt tggaacttgt
     8401 ggactatcgc ttggtgtcac aagtgatatt agtgatattt ccaaggtcgt actaatggta
     8461 ctcatgttta taggacgtgt tggcttaata tcatttatca ttatgatagc aggacgtcga
     8521 gaaccagata aattccatta tccaaaagaa cgtattcaaa taggataata taatagcaat
     8581 ctaagtttag ttaatgtaga ttttaactgg aacttagatt gcttttttag tttgtatttt
     8641 taacttattt tataagacga ttggttttga aaatggtaaa ctagtaacaa tgagaggtgt
     8701 aacatgatgg aaaaaaatga aaacattaat gtagagattt taactacgtc agatatgcat
     8761 agtcatttct taaatggtga ttatggttca aatatatata gagctggtac ttatgttaac
     8821 caagtaagag cacaaaatca tcgcgtcatt ttattagata gtggcggaag tttagctggc
     8881 tcgttagcgg cctattatta tgctattgtt gcaccttata aacgacatcc aatgataaag
     8941 ttgatgaaca gaatgcatta tgatgctagc ggtgtgagtc caagtgaatt caagtttggt
     9001 ttatcatttt taactcgttc aattgctttg gcacgttttc catggttatc agcaaatatt
     9061 gaatacaatg ttactaagga gccatatttt tcaacgccat attgtattaa acattttggt
     9121 gacttaaaaa ttgctatcgt aggcgtcaca gcagatggtt taatggaaaa tgagtattct
     9181 gaaatggaac aagatgtatc tattgaaaag acattagtgg catcaaaacg atggattaga
     9241 tatatccatg aagttgaaga gccagatttt ttgattgtaa tttatcatgg tggattgaat
     9301 aaaattagta atagcacgaa aaataaaaag gcaagttcga atgaagctga aaaattaatg
     9361 gaagaactcg gtgttataga tttaatgatt acagctcatc agcatcaaac aatagtaggt
     9421 caagatcatg aaacgtatta tgttcaggct ggtcaagatg caaaagagct tgtacatctt
     9481 tcgattaatt ttaaaaagag aacaacaact tatgatgttg aaagtattga ttctaaagtg
     9541 attgacttaa atgagtatga agaggatcaa gaattattag atttaacatt ctatgataga
     9601 aaagcagtgg cttattggtc acaggaaatc ataagtgata aaggtttgat gttatcagta
     9661 aatgggttac aagatttagt ctgtcaaaca catccatttt cgcaattatt acatgatgca
     9721 attcaccttg catttgataa tgatataaca tgtgtccacg tgcctatgaa cggagagaag
     9781 gggttgagtg gacagattcg aaatgaagat ttgtatcatg catacccata tccagataag
     9841 ccaatggata tgacaattag tggtcaaaat atcaaagata tattggagta tagttattca
     9901 catttagatt ttgttaacga gcaattaagc ttaacaatta ttgatgaaac gttatgtaca
     9961 atgtggcaag gattcaatta tgagattgat atgaatcaag aacctgggca acgagtaatg
    10021 ttagatcaaa ttgatttgac taagagttat agagttacaa tgactgacta ttgttatcgt
    10081 aactacaaga attatttgaa aaatgctatt atacatgaat catacgatga aacaatgagt
    10141 acattaattg cagagaagtt aagagatccg aattatcgta tttcatgtag tgataatttt
    10201 gtagttaaaa acaggtaaat attgctatgt aataaattaa ttataagttt aacaattcta
    10261 aaaacctttc ttagagaaga ttatctagga aaggttttta gaattttaaa attgatataa
    10321 aagaacagtg aaaatctcat tcattatata tataagtaaa caaaaaagct taaatggtat
    10381 ataccattta agcaagtaac ggaaacggag ggattcgaac cctcgcgccg ctttcgcgac
    10441 ctacaccctt agcaggggcg cctcttcagc caacttgagt acgtttccaa tggctccaca
    10501 ggtaggactc gaacctacga ccgatcggtt aacagccgat agctctacca ctgagctact
    10561 gtggattaat ttgtatgtgt ttgaatatca agcacaaata ttattataac aagattaagt
    10621 taatttgcaa tagatacctt aaaaaaatat gcagaacatt tacactatat ttataaaaca
    10681 ttccgcatat tttaaaaata aacaatttat ttatcttcaa ataaagaata gcgtgtcaat
    10741 gcttcaaaca cattcaatgt ggctttatta taatctattg gttggtcggg attttttgat
    10801 atcatgcgag attgtttatc taccatgtaa tagtaaaaaa tggaattgtt atattgatgc
    10861 cataaactgt ggtatgaaac atgaagaatg attgattcat tattaataaa tgtcacttta
    10921 catttacgat tttttaattc tttaatactt tcgatataat gcatatttaa ccaaatattt
    10981 tcattttgtc tgtcagaatg tgttgggaaa aaataagttg gaaataatgg tgttagtaaa
    11041 ataggtggtt tactagaaat gccagtaatg cggtttgtct ctgctttctt gccaagataa
    11101 gtattaccat aaaatttgca agagcgttca atgattttct ggactttaaa aggattttga
    11161 atacgcgttt tgtcaaaccg aattatttca ctaccgtttc tttgatcgtc atcatcaaat
    11221 gctggtcgaa taaccatgtc tcctttgcgt atcacataaa tattttgaga atacataagc
    11281 aaaacctcgc tttattaagt tttaaaccat taatataaaa attcaattaa tgatataaag
    11341 atattttata ataaaattct gagttgtcaa gttattattt tggtgaaaat gtacaataat
    11401 ttttaactaa tagtcagaat attcattgat ttcaaaatta gaaaaatgta tacttattat
    11461 aaattaaaga aaggtagtgg tttctatgaa atacaatact aatgttaaac atacaacttt
    11521 agaagcgttt gtcacaaccg tcaatgattt gggtattgaa ttaattatca atgaagcact
    11581 tcgagaggta agaaaacgac agctcataga acttatagat gacgcactcg tcaataaaga
    11641 tgaagcagca tttaatcaat atacggcaga atacaaaaat ttggaggcat ttctcggtga
    11701 ataacattga ttcgaattcc ataacgcaat cataaaagga ctattcttaa catctcatac
    11761 atgtaagaat agtcctttaa tcgtttaaga cattaatcta attaattcat gtctaactat
    11821 gtcaccgaaa tagtgatata aatcatattc tgatagtgct tcttctatat gctcaaagtc
    11881 gtgtagacag ccaactaatg cattttcaag atcagtgaca tctccgacac caaagaaatc
    11941 accgaaaatt tttgcatgtt cgattttacc tcgtttaaca tcaaacttaa tttgtacaaa
    12001 tcctttttca aatttttcct cgcgttcaaa gttatattta gggtttctac cataattcca
    12061 ttcccaagtt ctatatttgt cgttacttaa cttttcaata ttttcccaat cttcatccgt
    12121 taatttatat tcttctactt cagtttctcc aaagatagtt ttcaagatga tttttttaaa
    12181 ttcttcaatt tctaaagggt catttaaaaa ttcttgaatg tttgctactc gtttacgaac
    12241 agatttaata ccttttgatt taatcttagc tggattaact tttagtgcat tctgaacttc
    12301 gtctaaatca ctatttaaca tcaacgtacc atgactaaac attctatttt taactttaac
    12361 catggcattt cctgagattt tcgcttgtcc aacttgaata tcgttacgac cagttaattc
    12421 agcatttacg cctaaagatt gtaatgcttg aacaattggt tcagtgaatt tttggaaatt
    12481 gtggaaactg ttgccatcat catctgttat aaaactaaag tttaaattgc cagtatcatg
    12541 ataaacagcg ccaccaccag aaattcttct aactacatcg atgttgtgag catctatata
    12601 tgtctgattt acttcctcta tcgtattttg attctttcca acaatgatag atggtctatt
    12661 tatgtaaaat aaaaagtaac tttcttctgc tggtaaattt tttaaaacat attcttccat
    12721 tgctaagttt aaagttggat ctgtaatatt attattacta atgaatttca ttacaatctc
    12781 tcccttatat ctatatatat tctctactta tttatgcctt aactttgctc aaaatgccaa
    12841 ttatatactc acaaatcatt ctaaatatcg gcttaaagtt acattttatt atttttgatt
    12901 gttaatagtt tatttgttaa gtgaatttta gtacaatata atttagttat gatttaagga
    12961 ggacttaaaa tgactgttgc agaagtgggt aacattgttg agtttatgga tggattaaga
    13021 ggtcgtgttg aaaaaatcaa cgataactct gttattgttg acttaacaat tatggaaaat
    13081 tttaatgacc ttgatttacc ggaaaaaact gttatcaatc ataaacgata taagattgtt
    13141 gaataagaag gtaagttata atgaataaaa tctcgaaggc tttaacttgg tttattataa
    13201 gtttcattat atttcatctc atattattta ttatgtgggg cgaacaccaa gaatactggt
    13261 atttatatac aggtataatg ctaattgctg gtatcagtta tgtattttat caaagagata
    13321 ttgaatctaa gcggttgctt acatcaattg gtgttggtat tattacggca attattttaa
    13381 ttatgcttca acttttattc tcacttataa cttctaattt aagttatagt tcattaatta
    13441 aagaattagc aagaacaggt gtcaattgga agtggcaaat gttagtaact ttactttttg
    13501 tcattccatg tcacgagtta tatatgagaa ctgttttaca aaaagaatta acacattttt
    13561 caataccgaa atgggtagct atattaataa ctgcaatttg ttctagttca ttatttattt
    13621 atttagataa ttggtggata gtaacattta tatttgttgc acaagtgata ttatcattaa
    13681 gttatgagta tactcgacgc atagcaacaa catccgttgc gcaaattgta gctattatat
    13741 tgttattaat ttttaatgct taaataagct tttcttagac gtctgtgttc taagaaaagc
    13801 ttttttgctt aagaatagca atacgaagat tcgaggcatg cttcattata gtggtaatat
    13861 ttttcgagca agttgaattg atggtggcta tctgagtaaa ggggggtggt gcctatggca
    13921 ttacttaaca cttttgaaag gaaaagccta ttgtgacatc tattgcaaac gcattacatt
    13981 taatgttaag tttcggtatg tttatcgtca ctttcattgg tatagtagta gcaataataa
    14041 atttaagcaa taaaaaataa ccatcatttc aaaactttga catagaatga tggttaaaga
    14101 aaatctcatt tagtcaccgt ctttttaacg ggctcattag gcgacatgtt actgcatgtc
    14161 gtctttttac atttttatag taacatatct tttatttaat tgtctatgtt tattagatgt
    14221 gtaacaaaat tttgaagtat ttttcgtata ttgcctgcta aacatgtcag atttgaaagg
    14281 aaaatcatac tgtggtagaa atcaattatg attatatggt agtacttata aataagtgat
    14341 ttctattgaa tatgtaatga agttcatata ttaataaaac tttcattggt atagtagtcg
    14401 caataattaa tttaaacaat aaaaaataac catcatttcc aaactttgac aaagaataat
    14461 ggttaaagca aacctcattt agtcaccgtc ttttaacggg ttcaataggc gacatgttcc
    14521 tgtatatcgt ctatttatgc actgcgcaat ttaataataa tacaattaca ctttgatgtc
    14581 catttaacat gaagtagttg aaatttgtag caaataaatt catctttaaa tattcagaaa
    14641 attctgtata atttaaatag agagatatag attaaatatg aagaggtgtt tttatagaag
    14701 aataaaattt ttggcactat attatattta actttagcac ttggattatc aacagcagct
    14761 tatgcatcta cagaatacgc agaaggaggc acttggagtc acggtgtcgg cagtaagtat
    14821 gtttggtctt attattatca tggtcataaa ggacatggtg caacagctat tggaaaatat
    14881 agatcattta gtggttatac aagagctggt gtaaaagcaa aaggatcagc tactaaacat
    14941 aattgctgga tcaatagagc gtattataac atttattaaa tactaaaaaa tcatagaaaa
    15001 taaacaacgc aagaggtaca acatgaaatg gttcaaatta atacttgatg ttacaatctt
    15061 cattctgatt gctatattgt tatttgttta tacatataaa gaaaacgaag aaatattgcc
    15121 tgatactaaa taccctatag cagtaactga ctggaataaa aaatatagta aaaatgagat
    15181 ttataaacat ataaatcaat tcgctaaaaa tgagaacgta gcaatctata aatcaacttc
    15241 aaattataca aacaaaaacg tagataaaga tatatatgta tttaataaat caaaagcaac
    15301 aactatcact ccttttaatg ctaaatataa cattcattat ttaagtgacg acgaagtatt
    15361 aaaaaaagat atcaaaggga gttattttgt aaaagacaaa aattttgacg tgtctaaatt
    15421 cataaatttt ttaaaagaat atggtgttac tgctgaatca tacaaaatag atcatatgat
    15481 gattgccgtt ggtgtcatta aacaaatgaa tatagtagtt ccattatcct cacttttaat
    15541 cgtttatttt atttattata ttttcgaaaa gaacattaat ttcaaagcgt atgcgattaa
    15601 gtatttaaat ggttttacat taagaaaaat aattttcgaa aatttttcaa agaaatgcac
    15661 gtattgggta acgttaatca taactcaaat tcttttaact acaagtgtac tttggatatt
    15721 aaattacacg ggtaatttag atttattcat attaagaata gttctgcttt catgtctttt
    15781 cattttaacg attagtgtta ttaatttatg gactttctta atgttactaa atttaaatat
    15841 tgccaatatg attaaaggta agcagcactt taaaacaatt cgttttatta atacagtttg
    15901 taaaagtatt ctcttagtac taatagctaa tgtaatgata gaaaatacta gtgttattaa
    15961 agatttgaat aaaataaaag aaactgagaa atattggaat gtattagatg attattacac
    16021 gattgaattt gcaccttatc acgaaacaaa acaaagtttg attgataata tggtgcgatc
    16081 agaacaatta gtaaaggcta gtgaagcaga aaataatgcg attttattca aaccaaaggg
    16141 tgactccgtt gacaatgaca acttttcacc tgatgagggg aatgtaatat tagtaaataa
    16201 tcagttttgg tcgatttatc acaagcagtt tcaacctgat attccaataa aaaatcaaaa
    16261 aaataatgtc gaagtaatta ttccacaaaa gtttcatgca atgcgtaatg aaatcaatca
    16321 agcatatcat tcatggtttg aatttgtaca taataaaaat aataaagaga gtaagttatc
    16381 tatacagttt atcaacaaaa atgattatcg aatttttaca tttgatgcac gagatagtcg
    16441 ccatttgtca tttatagagg cgccaatcat tgtgaatgtt caggcatcag atttatcgaa
    16501 tgatttttat tatgccatga tcagtcaagg cgggtattta ttcaaaaatt atgacgcgct
    16561 agtaaaaaat attgaaaagt atcatcttga tggggaaatt agtggaataa ccaattataa
    16621 agatagcgtg atggaaatgt atcatgaaaa caatttgaaa ttaacagtac tcaacttttc
    16681 acaaatcatt atcgcaatca ttttaataat tattatttta tttgatgtga aatattattt
    16741 tgaacaacat cgaaaattac tcgtaatcaa aaagctatat ggttattcaa cattaagagc
    16801 caattaccaa tacttattaa taaataatat agttgttgtt tttattggaa tattgacgaa
    16861 tgtaatttta cattctcagt atataatgat gatatttgta acgattattg tcgttcaaat
    16921 attattgcag atttgcagcc tatactatca tggccgacgt tttaatggag ttatcaagga
    16981 gttttaacta tgaaatttat cattgcaata ttattaggat taatattatc cattactatt
    17041 gcttttacaa tcatacatca tcctatactt gatcgtttta atcctttctt aaaaacggag
    17101 tatagttatg ccaaagtgcc aaaaggtacg caacaatatg ttaatattac ggcttatagt
    17161 gaaagagggg aaaagcttga ttataaatta acatttaatg gattttcacc tagtagaacg
    17221 tatgtcgaaa taaagcataa agggcaatat gtcatatcga tcacatatgt tgaaaaagag
    17281 gatacaccaa aagaggtaag acaagaatga tagaattaaa agatttaacc atacaaaaag
    17341 gtaatacaca tattttgaag aaacttaatt tgaaatttca atgtggaaaa tcatatgcac
    17401 ttattggtaa aagtggatgc ggaaaatcta cattattaaa tactattgct ggacttgaaa
    17461 aaacagggaa acaatatgtc tattttaatg gtcaattaga acaatttaaa tctaattttt
    17521 acagagataa attaggatat ttatttcaaa attatggatt aatcgataat ttgacagtaa
    17581 atgaaaattt agatattgga ttagcatata aaaaaataag taagaaagaa aaagaacaat
    17641 taaagatacg ttatatagaa cagtttggtc tgtcaaacag tttaaaaaga aaagttcata
    17701 cgctaagtgg aggtgaacaa caacgtgtcg ctttaattag aatgatgtta aaagatccga
    17761 ttgttatgtt agctgatgaa ccaacgggtg cgttagatcc taaaacagga cagatgatta
    17821 ttcaatcatt atttgatttg gtcgatgaaa ataaagtgct gattttagca acacatgata
    17881 tggctattgc aaatcaatgt gacgaaataa tagatttaga acagtataga aaagtagcat
    17941 ctatgtgata tccaaaagat aaaattaaaa gccaatcaat gggaaatgtt gacttcaaca
    18001 ctccgtttga ttggctttta taatgtgtta ctaagttatg aaagtaacaa cggcaaactg
    18061 aaaaaaagca atataataat atttaatacg agtagtaata aatgtaattg atttttcgtt
    18121 ttaatatagc aaaaaacaat gactaaagat aacaacaata tcatgattgc acctgggaag
    18181 aaccataatg ctgaagctgt gtaccaaatc attggtaacg ccataataat aaaagatata
    18241 agacaagaaa ggataccaat aatattataa gttctagtca aaattacacc tccaattttc
    18301 attttaaaat gatatgcgca aaacaatcat tttaaataca tcatacaata aaattaaatt
    18361 gtgcggtaga agaatttgaa attaaattga attggcttga ttaaaaggtg attttataga
    18421 agataataaa aatggttatt taatagaaaa ccataatata aacgacatgg ctgataaaat
    18481 attaaagctt gttaataatg atgttttagc agaggagttt ggttcgaaag cgagagaaaa
    18541 cattatagaa aaatattcaa cggaatcaac attagaaaaa tggttaaatc ttttcaatag
    18601 ctaaatgaaa aaatcctagg tattcatgag tacctaggat ttttacgcat tatatataca
    18661 aaaaaagaga ggatagtcct ctcaaataat agttaataaa attgtagcca tttcttccag
    18721 ctgtaactac taatacaagc taagttcatt acgatatgta tgatttcaaa ttcataacca
    18781 cttacatatc ctcttgtaag tttaagtgtg aagattgagc ctaacataac acaaatataa
    18841 aaaacattaa cataaggcgt taaaaagccg ataataagtg ctaaacctcc aacaacttca
    18901 ccaatggaca tcaatactgc gatggtaggt ggtaaaccta aagagcctaa gaagtgaatt
    18961 gttccatcta aatcaacaaa tttcaaagta ccatgcacta agaatgatgt tgctaacatc
    19021 catctaatta aaagcatacc taatttcatc atgtcacctc caacatacat ttttttctta
    19081 aaacatagtc caaattatat ttgtaaagaa gtggaaagta aagattattt ataaaaataa
    19141 ttattaaata tttattaaat gttctattgt attgaacaat tgttgtagaa agatgtttaa
    19201 gtcatcagtt actttttgta tttataaata aagattagta cagcatagtg caaagattat
    19261 agggaaatga attaactatt gcatcgctat ttatgaatcg taaacactat tatgaaattg
    19321 caagagtagt atggacaatt agaatgatgg tttgagataa atgcgtgtta ttaaccagtg
    19381 cgtcatcttc aaattagagg ccatttgctg tttataataa gaagatttga taatcaacta
    19441 tgataagaaa aaaataataa catcctaaat atatcataaa caaattaaat gataaaataa
    19501 taatgtggtt ttctattaaa gttgtttgga ggtaaatgtg tgaataggaa tatcgttaaa
    19561 ttagttgtgt ttatgctaat cttagttgta gcagtagcgg gttgtggaca aaaagatact
    19621 gaagagaaaa ctgaaatgac gacaataaaa gatgaattag gaactgaaaa aattaagaaa
    19681 aatcctaaac gtgttattgt attagaatat agttttgctg attatttagc agcattagat
    19741 atgaaacctg ttggtattgc agatgatggc agcactaaaa atataacaaa gtcagtaaga
    19801 gataagattg gagcatatga atcggttgga tctagaccgc aaccgaatat ggaagtaata
    19861 agtaaattaa aaccggattt gatcattgca gatgttagca gacataagaa aatcaaatca
    19921 gaattgagca aaattgcgcc gacaatcatg ttagttagcg gtacgggaga ttataatgca
    19981 aatattgaag catttaaaac agtcgctaaa gcagtaggca aagagaaaga aggcgagaag
    20041 cgtctggaaa agcatgataa aataagcgga gattagaaag aaaattgaac agagtacgtt
    20101 aaaatctgca tttgcattcg gtatctcaag agcaggtatg tttattaata atgaagatac
    20161 atttatggga caattcttaa ttaaaatggg tattcaacct gaagtcacaa aagacaaaac
    20221 tgcgcatgtt ggtgaacgca agggtggccc ttatatatat ttaaataatg aagagcttgc
    20281 caatatcaat ccaaaagtta tgattttagc tacgaatgga aaaacagata aaaatagaac
    20341 gaaattcatt gatcctgcag tttggaaatc attaaaagct gtgaaagata ataaagttta
    20401 tgacgttgac cgaaataagt ggttgcaatc aagaggtatt atcgcaagtg aaagtatggc
    20461 agaagattta gagaaaattg cagaaaaagc aaaataaaaa tacagcgcca ctcggaaatc
    20521 atataagagt ggcgctgtat ttttaattat gtttgttatt tgttgaatgt gatgatttac
    20581 ctgaaagttt atttcgaata aattttaata cataaccgac aaggattgtt ttaacaattc
    20641 ttttaatgaa ttgacgcatc gttacatacc tcatttctct ttatcttatg aactatatac
    20701 ccattcatat atgcttttta aacgtcattg tcacaattta atttttaggg aatataatat
    20761 aaccgtctct gtctgctttt ttagtaaaaa tgacaaaaat ggcatgtatt attgagatga
    20821 tggtagggat acctgtccag aaaaataata agtgaaaaag accttgtcca aatttatcag
    20881 cataaaattt atgaatacct aaacctccaa gaaataatgc aacaataaca taaatggctt
    20941 tattgacttt catttgtaaa tcctccttaa ctataattct acttaaattc gttgtgaaaa
    21001 ccaatatttc taactttaga attttcaaac tttctaaaat tataagtata tctttttaaa
    21061 ataagctaga atttctatat aataaatgtt aataacgtaa aagggaatga tgacatagtg
    21121 atacgtcaag cacgtccaga ggaccgattt gatattgcga agttagttta tatggtttgg
    21181 gatgatatgg aattagaatt ggtaaagcat ctacctaaag acatggtatt agatgcaatt
    21241 gaaaaaagct gtgttgatgc aacatatcga actttttatc agcatatttt agtttatgaa
    21301 gtagaaaata aagtagcagg ttgtattatt agctatagcg gtgaaaatga attgaaatat
    21361 gaaaaagcat gggcactact tgacttacca gaagaaataa aacaatatgg cacgccatta
    21421 cctgtaaaag aagctaaaga cgatgagtat tatatagaaa caattgcgac atttgcagca
    21481 tatagaggta gaggcattgc gacaaagtta ttaacgtcat tacttgaatc aaatacacat
    21541 gttaaatgga gtttgaattg cgatattaat aatgaagcag cattaaagtt atatcaaaaa
    21601 gtaggtttta tatctgatgg acagattgaa ttatacaagc acatgtatca tcatttaatt
    21661 gttaaataaa aaaactcgac agttcgaagt aagtcgattg ccgagtagta tcattttata
    21721 ttaaatgcct gcaaataatg cgctaatata aatacctaat gcatataata aaccgaaaaa
    21781 tgtatttgtt ttaccagcag cagccattgc tggcatcatt gtaggcggtg tatcattctt
    21841 cttgaaacgt ctgataactt taacaggcat tgggaatgat aacaacgcaa gtaagtaaaa
    21901 taatgagcca ccaggtttaa taatgatcgt aagtacaata aaggcataag cgataaagta
    21961 catgattgcc ataaatgtta aagaagcatt tttacctaat agaatgggta aagttttacg
    22021 accacttgct ttatctttga cacggtcgcg aatattgtta gccatattaa ttaaaccgat
    22081 agtgattact ataggtacac ttaaccaaat tacatagctt tgaatattgc cagtttgaat
    22141 aaagaatgca ataacgataa taaacatacc cataaatacg cctgagaata attcaccgaa
    22201 aggcgtccat gaaataggga aagggccacc tgtatatagg taaccaacag ccatacatac
    22261 taatccaact ggtaataacc aaaatgaaga gttagcagct aaaaacaaac ctaatattgc
    22321 tgctaagatg taaaatgcaa tggctaatcg tagcacaagc tctgggctca taccgttgcg
    22381 tacaattgca ccaccaatgc ctacagattc atgatcatca aggccttttt tataatcata
    22441 gtattcgtta aacatattag ttgctgcttg aataagtaag catgctagta acatggcaat
    22501 gaataggctg attttaatat gatcttcgct accaagaaaa tatattttag atgctgctgt
    22561 accaactaaa acgggtacta cggaagcagt taatgtatga ggacgcatta aatgccaata
    22621 tttcttaact gtagaatatt gctgatattg attactcatt gaatacaaaa cctctttaaa
    22681 tcatattttt tataacaaag atattttaat agaaagtagc ataaaggtca attgacgtga
    22741 aaaattgcaa gataagttta agcaattctt gtaacacaat tatccaaaaa tgatacaata
    22801 taataatgag tgaaaaaaga cgaagaaaga agtgaaatgg atggctacgg gcgtattaga
    22861 ggacgatatt gtcaaagaga tatatgacag ctcaaaggaa tgggtttcag ttgaagtgaa
    22921 attatcacag tcactagacc cgagcacatt atttcatctc actgacaatg aggcaggaga
    22981 tcgcttttat atgcgtttga atgataatcg aacgtcatat tttggctaca aagcaaatca
    23041 attattcaaa aataattcta aaaataaaca atctattttt aaagactggg aaaaattaaa
    23101 acataacatc acatttatac atccgcaatc tgagaaacat catcttcgag ttgttggagg
    23161 gtttcaattt tcaagtcata aatcagatga tgaatggcga gagtttggac taaatcattt
    23221 tgtattacct gaagttttaa tttcaactga taataatggg acatttttaa cttatacagt
    23281 taaaagggaa agttttactg ttgaggcatt gaacgattta atggatttgt tcaacaatat
    23341 atcggacata gatgtggacg agcaaattgg ggaaattact agaaatgaag atatttataa
    23401 agatgattgg cgtcaacttg tagtagaagc tatagaatct attaataatg aagaaaaaat
    23461 tgtactagca cgtagacggt taataaagtt cgataaagat atcagtattc catatattct
    23521 aaagcaagca tattctaaag aaaaaaacag ttatatattc ttgttagaat cacaagattc
    23581 tatattcttt tcacaaacac ctgaacaatt aataaaggtc aataataaaa tactatcgac
    23641 taaagctgta gcaggtacaa ttaaacgttc acaagatgag gacgaagata caaaaaatgt
    23701 tgacgcattt ttaaaagata ataaaaactt aattgaacat cgatttgttg ttgacagtat
    23761 tttacatgat attaaacctt atatcactga attacattat gataagacgc ctaaaattct
    23821 aaaaaatgat catttatatc acttatacac tgaaataaag gcgccactga aggatgattc
    23881 gtatattagt ttaattgatc atttacatcc aacacctgct ttaggtggct atccaaaaga
    23941 atttgcaatg gattttattg agcagaaaga atttggtacg cgaggattat atggtgcacc
    24001 ggttggctat atagatatat acgatgattg tgaatttatt gttgcaattc ggtcaatgct
    24061 gattaagaaa gcacaagcaa cattatttgc agggtgtggc attgttaaag attctgatcc
    24121 agatagtgaa ttggcagaaa cgaaccttaa gttcacacct atgatgaatg cattaggagt
    24181 cgatatgaat gggaaatcat aaagcagctt taacgaagca agtttttaca tttgcatctg
    24241 agttatatgc gtacggcgta agggaagtag ttatcagtcc gggatcacgc tcaacgccac
    24301 ttgcacttgc atttgaagca catccaaata ttaaaacatg gatacacccc gatgagcgaa
    24361 gtgcagcttt ttttgcggta ggattaatta aaggcagtga aagacctgtc gctatattat
    24421 gtacgtcagg tacagcagca gcgaattata cgcctgcaat tgctgaaagc caaattagta
    24481 gaattccttt aatcgtttta acaagtgacc gtccgcatga attaagaagt gtaggcgcac
    24541 cacaagcgat taatcaagta aatatgttta ataattatgt aagttatgag ttcgatatgc
    24601 ctattgcaga tgatagtaaa gagaccattg atgcaattta ttatcaaatg caaattgcta
    24661 gtcaatattt atatggacca cataaagggc caattcattt taacttgcca tttagagatc
    24721 cgttaacacc tgatttgaat gcaacagaat tgttaacttc tgagatgaag attttaccgc
    24781 actatcaaaa aagtatagat gcatcggcat taagacacat tttaaataag aaaaaaggtt
    24841 taattattgt aggggatatg cagcaccaag aagttgatca aatactgacg tattcaacga
    24901 tatatgattt gcctatttta gctgatcctt taagtcattt aagaaaattt gatcatccga
    24961 atgttatctg tacatatgat ttgctgttta gaagcggctt agacttaaat gtggatttcg
    25021 taattcgtgt tggaaaacca gtgatttcta aaaagttgaa tcaatggtta aagaaaactg
    25081 atgcatttca aatattagtg caaaacaatg ataagattga tgtctttccg atagccccag
    25141 atatttcata tgagatttct gcgaatgatt tctttaggtc attaatggaa gacacgacca
    25201 tcaatcgagt aagttggtta gaaaaatggc aacgcttaga gaaaaaaggg cgtaaagaaa
    25261 ttaaatgtta tttggaacaa gctacagatg agagtgcatt cgttggtgaa ttgattaaga
    25321 aaacatctga aaaagatgca ttatttatta gtaatagtat gcctatcaga gatgtagata
    25381 acttgttatt gaataaaaat atagatgtct atgcgaatcg tggtgcgaat ggtattgatg
    25441 gtatcgtttc aactgcactg ggtatggctg tgcataaacg aataacatta ttgataggtg
    25501 atttatcatt ttatcatgat atgaatggac tattaatgtc aaaattaaat aatattcaga
    25561 tgaatattgt attattgaac aacgatggtg gcggtatttt ttcatattta ccacaaaaag
    25621 aaagtgcaac tgactatttt gaacggttgt ttggcacacc gacgggattg gattttgagt
    25681 atacagctaa gttatatcaa ttcgatttta aacgttttaa cagtgtttca gaatttaaaa
    25741 atgccacatt gttatctgaa acttcgacga tttatgaatt gataacgaat cgcgaagata
    25801 actttaaaca gcatcaaatt ttatatcaga aattgagtga aatgattcat gacacattat
    25861 aattactatg aagcaaacgt tgagaccaat caagttttag tattactgca tggttttctt
    25921 agcgacagtc gtacttatca taatcacatc gataaatata ctgatatctg tcatgtcatc
    25981 actatagact taccaggaca tggcgaagat cagtcttcaa tggatgaaac gtggaatttt
    26041 gattatatta cgacgttgtt agaccgaatt ttagataaat ataaagataa atcaataaca
    26101 ttgtttggat attcaatggg tgggcgtgtt gcgttatatt atgcaattaa tggtcacatc
    26161 cctatatcta atttgatatt agaaagtacg tcaccaggta ttaaagaaga agcaaatcaa
    26221 ttggaacgcc gtcttgttga tgatgcacgt gctaaagtat tagacatagc aggtattgaa
    26281 ttatttgtta atgattggga aaagttgcca ttatttcaat cgcaactaga attaccagtt
    26341 gaaatacaac atcaaataag acaacaacga ttgtctcaat cgccacataa aatggccaaa
    26401 gcattaagag attatggtac aggtcaaatg ccaaacttat ggccgcgcct gaaagaaatt
    26461 aaagtaccaa cattaatatt agctggagaa tgtgatgaaa aatttgtaca gattgcgaaa
    26521 aaaatggcaa atttaattcc taatagtaaa tgtaaattaa tttctgatac aggtcataca
    26581 attcatgtgg aagatagtga tgaatttgat acaatgatat taggattttt aaaggaggag
    26641 caaaatgact aacagacaat gggaaacact tagagaatat gatgaaatca aatatgaatt
    26701 ttacgaaggg attgctaagg taacaataaa tcgccctgaa gtacgcaatg cgtttacacc
    26761 taaaacagtt gctgaaatga ttgacgcatt ttcacgtgca cgtgatgatc aaaacgtttc
    26821 agttatcgta ttaactggtg aaggtgattt agcattctgt tctggtggtg accagaagaa
    26881 acgtggacat ggtggttatg taggtgaaga ccaaatccct cgcttaaatg tattagattt
    26941 acaacgttta attcgtatta ttccaaaacc ggttatcgcg atggtaaaag gttatgctgt
    27001 aggtggcggt aatgtactaa atgttgtttg tgacttaacg attgctgctg ataatgctat
    27061 ttttggacaa actggtccta aagtaggttc atttgatgcg ggttatggtt caggatattt
    27121 agcacgtatc gttggacata agaaagcacg tgaaatttgg tacttatgtc gtcaatacaa
    27181 tgcacaagaa gctttagata tgggtctagt aaatacagtg gtacctttag agaaagttga
    27241 agatgaaact gtgcaatggt gtaaagagat tatgaaacac tcaccaacag ctttacgatt
    27301 ccttaaagca gctatgaatg ctgacacaga tggtttagct ggtttacaac aaatggctgg
    27361 ggatgcaaca ttgctttatt acacaactga tgaagcgaaa gaaggccgtg atgcgtttaa
    27421 agaaaaacgt gatcctgact tcgatcaatt ccctaaattc ccataagtta ttttgaatat
    27481 gatattaagt cacttgcgtc gtttattagc gacgataggt ggctttttta ttttataaga
    27541 atttaaaagg gaattttaat taattatcat aaagataagg tagtttgagt aaattaatag
    27601 agaaagaata aatgttaaag attattatta caatgaaaaa acgagctggt gagaaattga
    27661 attctcgcca acccgcttta tgaagtgaaa tcatttaaat tagttatact aagcgctcat
    27721 aaacgattgg tcgcgaagtg ccaatacctt gtttggatga cgtttgcatg aggatatgct
    27781 gtgtatcatc ataatcaaga atataaatga tttcttcatt atcaatagat gaaaatttaa
    27841 tgcgttgatg tgccgtatct ataaaaagaa tatgatattg attgtgactt gtatcatcgc
    27901 catgacgtat acaaattgat ttttgtaatt gatgattact ccaattacca atgaataaat
    27961 tgatattggt ttgttctaga tgtgtgagtt tggttgtgtc gtaaactaaa tttataaatt
    28021 gtagttgata catagtttta cctgccttta atcaatatct atattacttt ttagtaacct
    28081 atcattgaac cataccagtt ataatcacga ttgaatgata aatgtaatag gcttgaatct
    28141 gcatcttgga ttgataattc tgtatcccaa ggattccagt aaataagttt ttcttggtca
    28201 ttaattttag cattaccaac aactgctagc gcatgtccta aatgtgggtc attagggttt
    28261 tgagatacac tttgtgcaag gatcataatt cctacattat cttttgtaag ttgatcaact
    28321 tgttcatatg atggtacgcc ttcttgataa tgaatatctc tgccttgtga tttaccgtat
    28381 tcaatcattt gattagggaa tgttgagcaa ttaggaaggt cttgttcact tacttctggg
    28441 tataatgtac gcataatatc atgtgcatta taagtgtctg tatttttagt tgcatttaat
    28501 aatgctgcca tactgaaacc tgcacaccat gagttatcga attgttgttc tctaattttg
    28561 aagtttttta atgtattttc atattgaact tgatcttctt gtatcgcttc gttttcttca
    28621 actttagtag gtgttactgt attttttaac tcttgtttca attttgctga aactgtttta
    28681 gcactttctt tttcttttac attaccaggt agtggcgtag cttttactaa tctaactttg
    28741 ccatcttctt caaaataaaa ccctttttca tcagtaagaa cagtgatatt tgaattttta
    28801 tctttaattt ggtctaaatc tttagcgatg aagtttgaaa ttttaacact gtaattcatg
    28861 tcttcttttg atttgtttaa atcatcttta tttttagggc taagtgttaa agtataaaca
    28921 attttaccgt cttttataac tggataatag taactattat cttcttcacc attaaattta
    28981 taaattttaa aagcttcgcc aagttcatat ttaccagttt ttgcattact ttgtttatct
    29041 aatgctttag cataaccagc aaattgttgt tgtgctagat cttttacttt ttgaggtact
    29101 ttgtcactct taacattaat ttctagctgt ttagagtgtg aatcggcttt ggctttattg
    29161 ttattagcaa atgcgcctag tgataaaata agcattgaaa ccattatgat gcttataata
    29221 ttgaatactc tagatttata tgaactattc atataatacc ctccatttaa atcaaaatat
    29281 tttgcgttgc taagactttg cttatatttt atctagacga acttaattgt taattaagct
    29341 gcatctggat tgtctgaatt attgttatcg ccattgtctg gattatcagg gttattaggg
    29401 ttgtcagggt tattaggatt gtccggatta ttaggattgt ccggattatt aggattgtcc
    29461 ggattattag gattgtctgg gttatttggt tcatctgggt tgttagggtt atcaggatta
    29521 tctgggttat taggttggtc atcgttggca aaatggatat cttcaatatt ttgttttaag
    29581 aagttgcgta cattttcatt aataaatacc gcaccattaa attcatttgg tacaccgccc
    29641 caatgaattc cgattacttc atttttttca ttaaatacag gtgaacctga gttaccacca
    29701 gttgtactta aatcatattg catagcttcg cctttgaggt aagtgatttt tcctttactt
    29761 tcccacattg ttgctacagg tttatcacca ggatatcctg ttacagtaat attttggtta
    29821 acttgtgttt catcattatt actcattgtt gctggtttaa ctacttcgcc tatatgtttg
    29881 ttttgctcat taggggagaa tttaacgatt gctaaatcac cttcgcctga atatttagtg
    29941 atttgttcag cagtgaaacc accatttgga taattgtctt ggttaattgc agaagggaat
    30001 gcttttaaag catgaggatc accgtgcgta gcatctacga cgtgtttatt tgttaaaagt
    30061 gtatctttac ctacaactac accggaagca ataaatgtac cagtaggtgc ttcaacttga
    30121 atataagtaa caggtgcata atgaccattc gttgtatctg tgatttggtg acgatcgtta
    30181 tttggtaata taacattagc gcgttcacgt tgttctaatg gtttaaggtt accgcctttt
    30241 tgaatcttag gtgtttgctg tttgtctgtc tgcgtttgtt gtggatgatt gtccatagct
    30301 tttgaagata acgcatttgc tgctggagaa ctcacaagtg tcgctgttgt caaagttgca
    30361 acgaataaag aactaacttt taaaaattta cctttcatct aaaaacctcc aaaaaattta
    30421 tttacaagtt aaatataaca ctaaaatttt ttaagtcaat aagaatatat aaataaatta
    30481 aaaagttttt gtaaagatta gagtttacaa aaacattaag ggaattaaaa ttgaattgta
    30541 ttatacttta ttcgattgtg ttaaattgat aaggttgtca attgtttgca tttatctaaa
    30601 agaataaata ggtaagcaat tgaggactaa gggaaagtat ttgattataa taataaatag
    30661 taacttttga ataataattg tttagccaaa ggtagattta tatgaatggt gatatattat
    30721 ttgagtgctt aagtttcgaa gaacaattat aagttagcat attaaaacct tttgatagaa
    30781 tcattttgag tgaggtgttt aaaggagagg aatgtaactc ggtagtattt acagtctcta
    30841 tagagtatta tttaaaactt atagaaaata aaaaactgaa cgtactatga atttagttca
    30901 cgacgtccag ttcaacatat tatttttatt tagtatttaa atatttagca agtctcttca
    30961 taccttcttt taaaacatcc atttcataag cataggaaat ccttacaaat cctttaccga
    31021 attctgtaaa ggatgagcct ggaacgattg ctaaatgtgt tgattcaagt aaatcgacac
    31081 aaaattcgaa atcgtcatcg gtgatatgtt taatacttgg gaaaatataa aacgcgcctt
    31141 caggttgagc ggtaatctca aaacctaatt tagttaattc agatactaaa taatttcttc
    31201 gttctacata agcttcgttc atatatttag gagcttctaa tccttcgtta agtgctgtta
    31261 tacatgctat ttgagctgga acattggcac aaatacaatt atacgcatgc ataaatgtta
    31321 atttttcaat gagatattga ggtcctaata gaaaaccaat tcttattcca gttgctgagt
    31381 gtgatttact taaaccacca attaatatta attgatcacg aatgtcttca aattcagcga
    31441 aagatacatg tttaccacta aatgtatttt cagcataaat ctcatcgcta ataataaata
    31501 tcggatattt ttttaataca tttacgatat ttaaaacttc atttcttttt aaaactacgc
    31561 cagttggatt agtcggataa tttaacaaga cagcttttgt ctttggagaa atatgacttt
    31621 ctaacgcatc aggtgtaatt ttgaattgtg ttgctgttgt atcaatataa attggtttac
    31681 cacctagtac ttcgatgagt ggtatgtagc ctgcataaat tggtcccggt attataattt
    31741 catctccagg ctctatgata gaacgtaacg ttgtgtctat tgcttcacta gctccatttg
    31801 tcacaataat ttcttcagga tcatagtaaa aatgataacg atttttgaag tattgactaa
    31861 ttgcttcgcg agtttctaat aaccctttat tgtgagagta tgaagtttga ttattgttta
    31921 tggcatcgat atatgcacgt ttcactacgt ctggcatagg aaagtcaggt tgcccaattg
    31981 ttaaattaac acaatcatca agacctttca tgcggtttga aaattggcga atacttgggg
    32041 ctcttaaata tttagaatta gaatttaaag aaagtttcat ttgtgacacc tcaaatataa
    32101 atcaaatatt gtctaaaaat ttagaaatta ataatatcat aacatacttt taaagcaaaa
    32161 aagggtaaat tacttaagct ttatttgaaa aacgaaaaat gtctaaatac actgtagtaa
    32221 ctacttttca aaatgaataa agtggttaca gttaatgtac ttagacatta tataattatg
    32281 agtctttaaa ctgtgatggt ctttgtaaat taattattgg atttgtccat ttacaaacaa
    32341 agtttgtaga taatacatat acgatgatta cagatatact tattaaataa agatacgtca
    32401 ttaatgatat aggattatcg aatgggtacc attcaaatcc tctaacaatg ccaataatta
    32461 aaccatgtaa taaatatacg tatagcgtac gactaccaat ataagtatat aattttttct
    32521 ttgttgatat taaatttaga aacgcagtca ttgcgattaa tataattcca tataatataa
    32581 gtcgtttaaa aggactgaat acactctgtc cttcattttc aagtgaagta tatggtgaac
    32641 ttcctaataa ccaatctgca ttgataggat gaatcacgta aatgataaaa aacaaaataa
    32701 acgtaatgat agatactggt attagttttt tatttttaaa aatagccgta tgttttttgg
    32761 tgaaaatgta acctaggtaa aatattggga aaaatacgat tgtccttgaa atgcttaagt
    32821 agctatcgat gtttcctgaa aaacctgctc caatagatat aataattgaa actgatagca
    32881 ctttatatgg attaaatctt ctaactatta ctaaaatgac atgaaagaaa aatagcgtga
    32941 tcaaaaacca taacgcaaat actgggttaa aaggatcaag ttgtaattcg tcacttttac
    33001 ctgttaagaa ataatatatt gaaaagaatg caaaaaatat catataaggt actatcaaac
    33061 gttttgaaat tttttctaaa tagtatggtt tatcaatatt tttcgcgaaa taaccagata
    33121 taaacaaaaa tgttggcata tggaaactat aaataactag gtataatgct gataaatatt
    33181 tatcgccact agtgtagggt tgtaacatat gtccaaatac gactaataat attaaaattg
    33241 ctcttgcgtt gtcaaaaaaa taatctctct cttttaatga agtcatattt tatctccttt
    33301 atgtccataa
//
LOCUS       DAPSKH010000031        33288 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPSKH010000031 DAPSKH010000000
VERSION     DAPSKH010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 33288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33288
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.031"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..298
                     /locus_tag="RPH49_001465"
     CDS             <1..298
                     /locus_tag="RPH49_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5124611.1"
                     /translation="NYDRLSQYDLTMKISREQSIVSRWIKKLVLKGYITSQQSSEDLR
                     CKELILTDQARTLISQINNARCELIEARCQCLSEVELDNLNQLLDKLNQRRISL"
     gene            325..435
                     /locus_tag="RPH49_001466"
     CDS             325..435
                     /locus_tag="RPH49_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124612.1"
                     /translation="MSLCTQQKLNHELQAKVAVIVKIDGKQSPLFLLVYV"
     gene            complement(506..4279)
                     /locus_tag="RPH49_001467"
     CDS             complement(506..4279)
                     /locus_tag="RPH49_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDY5124613.1"
                     /translation="MAKKFNYKLPSMVALTLVGSAVTAHQVQAAETTQDQTTNKNVLD
                     SNKVKATTEQAKAEVKNPTQNISGTQVYQDPAIVQPKAANKTGNAQVNQKVDTTQVNG
                     DTRETQSTTSNNAKPVTKTTNTTASKTNNNVTSAGYSLVDDEDDNSENQINPELIKSA
                     AKPAALETQYKAAAPKATPVAPKAKTEATPKVTTFSASAQPRSVAAAPKTSLPKYKPQ
                     VNSSINDYIRKNNLKAPKIEEDYTSYFPKYAYRNGVGRPEGIVVHDTANDRSTINGEI
                     SYMKNNYQNAFVHAFVDGDRIIETAPTDYLSWGVGAVGNPRFINVEIVHTHDYASFAR
                     SMNNYADYAATQLQYYGLKPDSAEYDGNGTVWTHYAVSKYLGGTDHADPHGYLRSHNY
                     SYDQLYDLINEKYLIKMGKVAPWGTQSTTTPTTPSKPTTPSKPSTPSTGKLTVDANNG
                     VAQIKPTNSGLYTTVYDKTGKATNEVQKTFAVSKTATLGNQKFYLVQDYNSGNKFGWV
                     KEGDVVYNTAKSPVNVNQSYSIKPGTKLYTVPWGTSKQVAGSVSGSGNQTFKASKQQQ
                     IDKSIYLYGSVNGKSGWVSKAYLVDTAKPTPAPTPKPSTPTTNNKLTVSALNGVAQIN
                     AKNNGLFTTVYDKTGKPTKEVQKTFSVTKEASLGGNKFYLVKDYNSPTLIGWVKQGDV
                     IYNNAKSPVNVMQTYTVKPGTKLYSVPWGTYKQEAGAVSGTGNQTFKATKQQQIDKSI
                     YLYGTVNGKSGWISKAYLAVPAAPKKAVEQPKTAVKAYAVTKPQTTQTVSKIAQVKPN
                     NTGIRASVYEKTAKNGAKYADRTFYVTKERAHGNETYVLLNNTSHNIPLGWFNVKDLN
                     VQNLGKEVKTTQKYTVNKSNNGLSMVPWGTKNQVILTGNNIAQGTFNAAKQVSVGKDV
                     YLYGTINNRTGWVNAKDLTAPTAVKPTTSAAKDYNYTYVIKNGNGYYYVTPNSDTAKY
                     SLKAFNEQPFSVVKEQVINGQTWYYGKLSNGKLAWIKSTDLAKELIKYNQTGMTLNQV
                     AQIQAGLQYKPQVQRVPGKWTDANFNDVKHAMDTKRLAQDPALKYQFLRLDQPQNISI
                     DKINQFLKGKGVLENQGAAFNKAAQMYGINEVYLISHALLETGNGTSQLAKGADVVNN
                     KVVTNSNTKYHNVFGIAAYDNDPLREGIKYAKQAGWDTVSKAIVGGAKFIGNSYVKAG
                     QNTLYKMRWNPAHPGTHQYATDVDWANINAKIIKGYYDKMGEVGKYFDIPQYK"
     gene            complement(4507..4941)
                     /locus_tag="RPH49_001468"
     CDS             complement(4507..4941)
                     /locus_tag="RPH49_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5124614.1"
                     /translation="MFLKVNNQKMLEDCFYIRKKVFVEEQGVPEESEIDEYESESIHL
                     IGYDNGQPVATARIRPINETTVKIERVAVMKSHRGQGMGRMLMQAVESLAIDEGFYVA
                     TMNAQCHAIPFYESLNFKMRGNIFLEEGIEHIEMTKKLTSLN"
     gene            complement(5098..5568)
                     /locus_tag="RPH49_001469"
     CDS             complement(5098..5568)
                     /locus_tag="RPH49_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499548.1"
                     /note="Essential protein for resistance to osmotic stress
                     from salt; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic stress response protein"
                     /protein_id="HDY5124615.1"
                     /translation="MSRKTYEKIANINGMFNMLEQQIIHSQDMAHFRSEFFYVNHEHR
                     ENYEALLIYYKNSIENPIVDGACYILALPEIFNSVDVFESELPFSWVYDENGITETMK
                     SLSIPLQYLVAAALEVTDVNIFKPSGFTMGMNNWNIAQMRIFWQYTAIIRKEAL"
     gene            complement(5616..6842)
                     /locus_tag="RPH49_001470"
     CDS             complement(5616..6842)
                     /locus_tag="RPH49_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase"
                     /protein_id="HDY5124616.1"
                     /translation="MNKFLKYFLILLALVLIVVPIVFATLLFKTSQDAFESSQDSKNA
                     NRQSNLRDNKVNPEEQPISILFLGIDDNDGRRKKGQDAEHSRSDAMILTTFNQSKHQI
                     RMLSIPRDTISYIPKVGYYDKITHAHAYGGPIAAMDSVEATMNVPVDYYVRVNMKAFV
                     EAVNELGGIYYDVPYDLNEPNTDDTGKIKIKKGYQKLNGDEALAVARTRHHDSDLKRG
                     QRQMELIKILFQKAQEVDSIDKLDNVIQIVGKNAKHNLTNSEIKALAKMYLTNDVEIK
                     TAQLKGKDDMLNGIYYYHPSVDSIQKYANLLRKDLELSPINDKNDFLDQRVINHYGSL
                     IPLTPLDSSLLRKEQNDTTDKDKSSNNSDDSNNSNSNNSVNNQQQPATDQNLNQNQGG
                     TQQTPQASNNQNGVVN"
     gene            7283..8476
                     /gene="fmtA"
                     /locus_tag="RPH49_001471"
     CDS             7283..8476
                     /gene="fmtA"
                     /locus_tag="RPH49_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala esterase FmtA"
                     /protein_id="HDY5124617.1"
                     /translation="MKFNKVKLVIHACVLLFIIISIGLVFHRLQTKTNSIEPIHKETK
                     LSDNAKYLVDRNKGKGEPSKLKEVYNSKDPKYKKIDQYLQNSLFNGSVAVYENGKLKM
                     SKGYGYQDFEKGIKNTPNTMFLIGSAQKFSTGLLLKQLEEEHKININDPVSKYIPWFK
                     TSKPIPLKDLMLHQSGLYKYKSSKDYKNLDQAVRAIQKRGIDPKKYKKHMYNDGNYLV
                     LAKVIEEVTGKSYAENYYTKIGDPLKLQHSAFYDEKSFRKYLAKGYSYNSTGLSFLKP
                     NVLEQYYGAGNIYMTPTDMGKLITQMQQYKLFSPKITNPLLHEFGTKQYPDEYRYGFY
                     VKPTLNRLNGGFFGQVFTVYYNDKYVVVLALNVKGNNEVRIKHIYNDILKQNKPYNTK
                     GVIVQ"
     gene            complement(8819..9097)
                     /gene="qoxD"
                     /locus_tag="RPH49_001472"
     CDS             complement(8819..9097)
                     /gene="qoxD"
                     /locus_tag="RPH49_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit IV"
                     /protein_id="HDY5124618.1"
                     /translation="MKHTVGFIASIVLTLLAVYVTLYTSLTFHAKLTIIFGFAFIQAG
                     LQLLMFMHLTEGKDGRLQTFKVIFALVITLCFVVGTYWVMQGGHSSHL"
     gene            complement(9106..9711)
                     /gene="qoxC"
                     /locus_tag="RPH49_001473"
     CDS             complement(9106..9711)
                     /gene="qoxC"
                     /locus_tag="RPH49_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit III"
                     /protein_id="HDY5124619.1"
                     /translation="MSHDTNTIDSRTHEGELNKLGFWIFITAEFALFGTLFATLLTLQ
                     HGGDYAGKMTTELFELPLVLIMTFALLFSSYTCGIAIYYMRQEKQKLMMFWMIITLLL
                     GLVFVGFEIYEFAHYASEGVNPTIGSYWSSFFILLGTHGCHVSLGIVWAICLLIQIQR
                     RGLDKYNAPKLFIVSLYWHFLDVVWVFIFTAVYMIGMVYSG"
     gene            complement(9701..11689)
                     /gene="qoxB"
                     /locus_tag="RPH49_001474"
     CDS             complement(9701..11689)
                     /gene="qoxB"
                     /locus_tag="RPH49_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit I"
                     /protein_id="HDY5124620.1"
                     /translation="MNFPWDQLLVKGNWMITMAQIGAPFLVIGLIAVITYFKLWKYLY
                     KEWFTSVDHKKIGIMYLICAVLMFVRGGIDALLIRAQLTVPDNKFLESNHYNEIFSTH
                     GVIMIIFMAMPFIFGLWNIVVPLQIGARDVAFPVLNNVSFWLFFAGMILFNLSFIIGG
                     SPAAGWTNYAPLAGEFSPGPGVNYYLIAIQISGLGTLATGINFFVTILRCKTPTMKFM
                     QMPMFTVTTFITTLIVILAFPPLTVALALMTTDRIFDTAFFTVAHGGMPMLWANFFWV
                     WGHPEVYIVILPAFGIYSEIIPTFARKRLFGHQSMVWATAGIAFLSFLVWVHHFFTMG
                     NGALINSFFSISTMLIGIPTGVKLFNWLLTLYKGRITFESPMLFSLAFIPNFLLGGVT
                     GVMLAMASADYQYHNTYFLVAHFHYTLVTGVVFACLAGLIFWYPKMMGYKLNETLNKW
                     CFWFFMIGFNVCFLPQFILGLDGMPRRLYTYMPSDGWFLLNLISTIGALLMAIGFLFL
                     VVSIVYSHFKSPREATGDNWDGLGRTLEWTTASAIPPKYNFAITPDWNDYDTFVDMKE
                     HGRHYLDNHNYKDIHMPNNTPVGFWIGIFMTIGGFFLIFETVIPALICLFGIFGTMIY
                     RSFQIDHGYHIPAAEVAETEARLREARIKEREAVSHES"
     gene            complement(11689..12789)
                     /gene="qoxA"
                     /locus_tag="RPH49_001475"
     CDS             complement(11689..12789)
                     /gene="qoxA"
                     /locus_tag="RPH49_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome aa3 quinol oxidase subunit II"
                     /protein_id="HDY5124621.1"
                     /translation="MSKFKSLLLLFGTLILLSGCSNIEIFNAKGPVASSQKFLILYSI
                     VFMLVICFVVLGMFAIFIYKYSYNKNAESGKMHHNAIIETIWFVIPIIIVAALAIPTV
                     KTLYDYEKPPKSEKDPMVVYAVSAGYKWFFAYPDEHIETVNTLTIPKDRPVVFKLQAM
                     DTMTSFWIPQLGGQKYAMTGMTMNWTLEASQTGTFRGRNSNFNGEGFSRQTFKVNAVS
                     QKDYDKWVKEVKGKKTLDQDTFDKQLLPSTPNKALEFNGTHMAFVDPAADPEYIFYAY
                     KRFNFELKDPNFTSEENMFKDVSDKPLIPARKAQITNANYKRHGMKLMILGNDEPYNN
                     EFKKDESKNAKEMKKISKDAQDQDNDDHGGGH"
     gene            complement(13361..13678)
                     /locus_tag="RPH49_001476"
     CDS             complement(13361..13678)
                     /locus_tag="RPH49_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5011 domain-containing protein"
                     /protein_id="HDY5124622.1"
                     /translation="MNKLLQSLSALGVSATLVTPNLNADATTNTTPQIKGANDIVIKK
                     GQDYNLLNGISAFDKEDGDLTDKIKVDGQIDTSKSGKYQIKYHVTDSDGAIKISTRYI
                     EVK"
     gene            complement(14343..15203)
                     /gene="folD"
                     /locus_tag="RPH49_001477"
     CDS             complement(14343..15203)
                     /gene="folD"
                     /locus_tag="RPH49_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDY5124623.1"
                     /translation="MVAKILDGKQIAKDYRQGLQDQVEALKEKGFTPKLSVILVGNDG
                     ASQSYVRSKKKAAEKIGMISEIVHLEETATEEEVLNELNRLNNDDSVSGILVQVPLPK
                     QVSEQKILEAINPDKDVDGFHPINIGKLYIDEQTFVPCTPLGIMEILKHADIDLEGKN
                     AVVIGRSHIVGQPVSKLLLQKNASVTILHSRSKDMASYLKDADVIVSAVGKPGLVTKD
                     VVKEGAVIIDVGNTPDENGKLKGDVDYDAVKEIAGAITPVPGGVGPLTITMVLNNTLL
                     AEKMRRGIDS"
     gene            15404..15886
                     /gene="purE"
                     /locus_tag="RPH49_001478"
     CDS             15404..15886
                     /gene="purE"
                     /locus_tag="RPH49_001478"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDY5124624.1"
                     /translation="MKVAVIMGSSSDWKIMQESCNMLDYFEIPYEKQVVSAHRTPKMM
                     VQFASEARESGIDIIIAGAGGAAHLPGMVASLTTLPVIGVPIETKSLKGIDSLLSIVQ
                     MPGGIPVATTAIGAAGAKNAGILAARMLSIQNPSLVEKLNHYESSLIQKVEDMQNELQ
                     "
     gene            15873..16997
                     /gene="purK"
                     /locus_tag="RPH49_001479"
     CDS             15873..16997
                     /gene="purK"
                     /locus_tag="RPH49_001479"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDY5124625.1"
                     /translation="MNFNKLKFGATIGIIGGGQLGKMMAQSAQKMGYKVAVLDPAEDC
                     PCRYVAHEFIQAKYDDEKALNQLGQKCDVITYEFENISAQQLKLLCEKYNIPQGYQAI
                     QLLQDRLTEKETLKSAGTKVVPFISVKESTDIDKAIETLGYPFIVKTRFGGYDGKGQV
                     LINNEKDLQEGFKLIETSECVAEKYLNIKKEVSLTVTRGNNNQITYFPLQENEHRNQI
                     LFKTIVPARIDKTAEAKEQVNKIIQSIHFIGTFTVEFFIDSNNQLYVNEIAPRPHNSG
                     HYSIEACDYSQFDTHILAVTGQSLPNSIELLKPAVMMNLLGKDLDLLENEFNEHPEWH
                     LHIYGKSERKDSRKMGHMTVLTNDVNQTEQDMYAKFEGSN"
     gene            17001..17705
                     /locus_tag="RPH49_001480"
     CDS             17001..17705
                     /locus_tag="RPH49_001480"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDY5124626.1"
                     /translation="MTLLYEGKAKRIFSTNQENELRVEYKDEVTAGNGAKKDTMAGKG
                     RLNNQITSIIFKYLQENGIESHFIKQLSETDQLVKPVKIIPLEVVVRNIASGSITKRL
                     GFENGEVFREPLVEFFYKNDALNDPLITDDHIKLLNIATDKDIETLKTKALEINQVLK
                     QLMDAMNLKLVDFKIEFGKTETGQILLADEISPDTCRIWDKATNANFDKDVYRNNTGS
                     LIETYQIFLNKLEDLK"
     gene            17705..17968
                     /gene="purS"
                     /locus_tag="RPH49_001481"
     CDS             17705..17968
                     /gene="purS"
                     /locus_tag="RPH49_001481"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDY5124627.1"
                     /translation="MKTIELHITLQPQVLDTQGQTLTRAVHDLGYAQVNDIRVGKVLY
                     MTVDEVSDEKVHNIITTLSEKLFANTVIEEYSYKVLDDEKENA"
     gene            17970..18641
                     /gene="purQ"
                     /locus_tag="RPH49_001482"
     CDS             17970..18641
                     /gene="purQ"
                     /locus_tag="RPH49_001482"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase I"
                     /protein_id="HDY5124628.1"
                     /translation="MKFAVLVFPGSNCDRDMFNAAIKSGVEAEYVDYRETSLSGFDGV
                     LIPGGFSFGDYLRSGAMASVAPIISEVKRLAAEGKPVLGVCNGFQILTEIGLLPGALL
                     HNDSHLFISRNEKLEIVNNQTAFTNLYEQGEKVIYPVAHGEGHYYCTDEIYQQLKANN
                     QIILKYVNNPNGSYDDIAGIVNEKGNVCGMMPHPERALETLLGTDSGVKLFEAMVKSW
                     REQHV"
     gene            18634..20823
                     /gene="purL"
                     /locus_tag="RPH49_001483"
     CDS             18634..20823
                     /gene="purL"
                     /locus_tag="RPH49_001483"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDY5124629.1"
                     /translation="MSKFIEPSVEEIKLEKVYQDMGLSDQEYEKVCDILGRQPNFTET
                     GIFSVMWSEHCSYKHSKPFLKQFPTSGEHVLMGPGEGAGVVDIGDNQAVVFKVESHNH
                     PSAIEPYQGAATGVGGIIRDIVSIGARPINLLNSLRFGELDNKQNQRLLKGVVKGIGG
                     YGNCIGIPTTAGEIEFDERYDGNPLVNAMCVGVINHDMIQKGTAKGVGNSVIYVGLKT
                     GRDGIHGATFASEELTEESESKRPSVQIGDPFVGKKLMEATLEAITFDELVGIQDMGA
                     AGLTSSSSEMAAKGGSGLHLRLEQVPTREPGISPYEMMLSETQERMLLVVEKGTEQKF
                     LDLFDKHELDSAVIGEVTDTNRFVLTYDDEVYADIPVEPLADEAPVYILEGEEKDYNT
                     SKNDYTHIDVKDTFFKLLKHPTIASKHYLYDQYDQQVGANTIIKPGLQASVVRVEGTN
                     KAIASTIDGEARYVYNNPYEGGKMVVAEAYRNLIAVGATPLAMTDCLNYGSPEKKEIY
                     QQLIDSTKGMAEACDILKTPVVSGNVSLYNETKGTSIFPTPVVGMVGLIENVNYLNDF
                     EPQVGDKLYLIGDTKDDFGGSQLEKLIYGKVNHEFESLDLSSEVEKGESIKTAIREGL
                     LSHVQTVGKGGLLITLAKLSAHYDLGLKSSIDITNAQLFSETQGRYVVSVKSGKTLNI
                     DNAIEIGLLTDSDNFKVTTPYTEISENVSDIKQIWEGAIAQCLTTQD"
     gene            20802..22286
                     /locus_tag="RPH49_001484"
     CDS             20802..22286
                     /locus_tag="RPH49_001484"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDY5124630.1"
                     /translation="MFNYSGLNEECGVFGIWNHPEAAQLTYMGLHSLQHRGQEGAGIV
                     VSDQNELKGERGLGLLTEAIKDDQMERLKGYQHAIGHVRYATSGNKGIENIQPFLYHF
                     YDMSVGICHNGNLINAKSLRQNLEKQGAIFHSSSDTEVIMHLIRRSKAPTFEEALKES
                     LRKIKGGFTFAILTKDALYGAVDPNAIRPLVVGKMKDGTYILASETCAIDVLGAEFVQ
                     DIHAGEYVVINDKGITVKSYTHHTTTAISAMEYIYFARPDSTIAGKNVHAVRKASGKK
                     LAQESPVNADMVIGVPNSSLSAASGYAEEIGLPYEMGLVKNQYVARTFIQPTQELREQ
                     GVRVKLSAVKDIVDGKNIILVDDSIVRGTTIRRIVKMLKDSGANKVHVRIASPEFMFP
                     SFYGIDVSTTAELISASKSPEEIKDYIGADSLAYLSVDGLIESIGLDYDAPYSGLCVE
                     SFTGDYPAGLYDYEANYKAHLSHRQKQYISKNKHFFDSEGNLNV"
     gene            22279..23307
                     /locus_tag="RPH49_001485"
     CDS             22279..23307
                     /locus_tag="RPH49_001485"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDY5124631.1"
                     /translation="MSKAYEQSGVNIHAGYEAVERMSSHVKRTMRKEVIGGLGGFGAT
                     FDLSQLNMTAPVLVSGTDGVGTKLKLAIDYGKHDSIGIDAVAMCVNDILTTGAEPLYF
                     LDYIATNKVVPEVIEQIVKGISDACVETNTALIGGETAEMGEMYHEGEYDVAGFAVGA
                     VEKDDYVDGSEVKEGQVVIGLASSGIHSNGYSLVRKLINESGIDLASNFDNRPFIDVF
                     LEPTKLYVKPVLALKKEVSIKAMNHITGGGFYENIPRALPAGYAARIDTTSFPTPKIF
                     DWLQQQGNIDTNEMYNIFNMGIGYTVIVDEKDASRALKILAEQNVEAYQIGHIVKNES
                     TAIELLGV"
     gene            23310..23876
                     /gene="purN"
                     /locus_tag="RPH49_001486"
     CDS             23310..23876
                     /gene="purN"
                     /locus_tag="RPH49_001486"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDY5124632.1"
                     /translation="MVKIAIFASGSGSNFENIVEHVESGKLENIEVTALYTDHQNAFC
                     IDRAKKHGIPVYINEPKQFDSKAAYEQHLVTLLNKDKVEWIILAGYMRLIGPDLLASF
                     AGKILNIHPSLLPKYKGIDAIGQAYHSGDTITGSTVHYVDSGMDTGEIIEQRKCDIRP
                     DDSKEQLEEKVKKLEYELYPSVIAKIVK"
     gene            23891..25369
                     /gene="purH"
                     /locus_tag="RPH49_001487"
     CDS             23891..25369
                     /gene="purH"
                     /locus_tag="RPH49_001487"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDY5124633.1"
                     /translation="MKKAILSVSNKTGIVEFAKALTQLNYELYSTGGTKRILDEANVP
                     VRSVSDLTHFPEIMDGRVKTLHPAVHGGILADRNKPQHLNELSEQHIDLIDMVVVNLY
                     PFQQTVANPDVTMDEAIENIDIGGPTMLRAAAKNYKHVTTIVHPADYHEVLTRLRNDS
                     LDESYRQSLMIKVFEHTAEYDEAIVRFFKGDKETLRYGENPQQSAYFVRTSNAKHTIA
                     GAKQLHGKQLSYNNIKDADATLALVKKFDTPAAVAVKHMNPCGVGIGDTIEQAFQHAY
                     EADSQSIFGGIVALNRAVTPELAEQLHSIFLEVIIAPKFTDEALDILKQKKNVRLLEI
                     DMTIDSNEEEFVSVSGGYLVQDKDNYVVPKDEMKVVTEVVPTDEQWEAMLLGWKVVPS
                     VKSNAIILSNNKQTVGIGAGQMNRVGAAKIALERAIEINDHVALVSDGFFPMGDTVEL
                     AAQHGIKAIIQPGGSIKDQDSIDMANKHGIAMVVTGTRHFKH"
     gene            25391..26638
                     /locus_tag="RPH49_001488"
     CDS             25391..26638
                     /locus_tag="RPH49_001488"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDY5124634.1"
                     /translation="MNILVIGAGGREHALAYKLNQSNLVKQVFVIPGNEAMTPIAEVH
                     TEISESNHQGILDFAKQQNVDWVVIGPEQPLIDGLADILRANGFKVFGPNKQAAQIEG
                     SKLFAKKIMEKYNIPTADYKEVERKKDALTYIENCELPVVVKKDGLAAGKGVIIADTI
                     EAARSAIEIMYGDEEEGTVVFETFLEGEEFSLMTFVNGDLAVPFDCIAQDHKRAFDHD
                     EGPNTGGMGAYCPVPHISDDVLKLTNETIAQPIAKAMLNEGYQFFGVLYIGAILTKNG
                     PKVIEFNARFGDPEAQVLLSRMESDLMQHIIDLDEGKRTEFKWKNESIVGVMLASKGY
                     PDAYEKGHKVSGFDLNENYFVSGLKKQGNTFVTSGGRVILAIGKGDNVQDAQRDAYEK
                     VSQIQSDHLFYRHDIANKALQLK"
     gene            complement(26904..27710)
                     /locus_tag="RPH49_001489"
     CDS             complement(26904..27710)
                     /locus_tag="RPH49_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDY5124635.1"
                     /translation="MYEQWKVRQSFVDDVNIITKLFLGIILFFFIIFVHNFDFMLYIT
                     ILMLVFLLMFNGTQFKITSIFITISIGFALLSSLFMILYGNGSHTILKFGFIHITTES
                     LVRGLHVSLRTIAISFFGILIALTSQVVMIFYSLMQHLKVKSKVAYAFMAAIRMIPLM
                     ISSLIQLRRSLKMRYQMIDAANYRGLKRFKHLIIPLLSQNIRKAHQLSVAMESKGFRD
                     GPRTYYYNVPFSYKDIIFIIVLIAIITLAYYCSITLPITGIDDVRLGRVG"
     gene            complement(27703..29103)
                     /locus_tag="RPH49_001490"
     CDS             complement(27703..29103)
                     /locus_tag="RPH49_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124636.1"
                     /translation="MLKVSDLRLKYPSGQRKIFDHLNITIQDKEKVLLLGPSGCGKST
                     LLNVLSGIVPNLIELPMKYDELIVDPLSGVIFQDPDSQFCMPKVYEELAFVLENRQVP
                     REDMDALIINALNMVNLNVTPETYIKDLSGGMKQKLAIVETILQQSKTLFLDEPTAML
                     DVQATEDLWTKLIELWEDQTVVIVEHKVKHIWNHVDRVILMDYNGNIIADECPEIILQ
                     KYVHLLSEYGVWHPRAWEFAPSRVDFPTTNSHLLQFKNGRIIRGKSTLLSFSDLEIGL
                     GEWITITGANGSGKTTLLESIMQLIKYQGDVYFENQRLTKIKHAAKHMYLVYQNPELQ
                     FITNSVYDEINIHFNHLSKDQSDDETIQLLKLLDLENVKDQHPYELSIGQKRRLSVAT
                     ALSSKADIIFLDEPTFGLDSHNTFQLIKLFQKRINLGQSIVMVTHDDEIIERYPSRRL
                     KISDGTLLDCDGDTNV"
     gene            complement(29118..29693)
                     /locus_tag="RPH49_001491"
     CDS             complement(29118..29693)
                     /locus_tag="RPH49_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDY5124637.1"
                     /translation="MSKGLKLSEILVTVLISVVFAVIYNLWWFVYNGVQATGLHLEQL
                     TNGVWFMAAIVCYLIIPKPGIALLAEFAAGAGETIIMGRFDIPTIVYAFIQGLACELV
                     FAIFKYQSRSVMVAMLAGFCTAIAAFPIDYFYGYLNEVAGWNLTLFIVFRLISGAVVA
                     GVLSYLLVKALDKTGVTKLFRPAAKEDYDNL"
     regulatory      complement(29770..29870)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(30192..30326)
                     /gene="graF"
                     /locus_tag="RPH49_001492"
     CDS             complement(30192..30326)
                     /gene="graF"
                     /locus_tag="RPH49_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance-associated protein GraF"
                     /protein_id="HDY5124638.1"
                     /translation="MSNENQNKKAAEKAKEVEEKLKDKKEEKTEDINQTKQDIQDTLN
                     "
     gene            30478..31773
                     /locus_tag="RPH49_001493"
     CDS             30478..31773
                     /locus_tag="RPH49_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124639.1"
                     /translation="MSFLRKHAEIIFSYLIGIVSLFTGLIILINLPLIKQLNGGKKVD
                     THVHNVWEFLNAFFSEIIKVMSRFIGNFPIVSAIVIIIFGILVMLIGHTLLRTIKYDY
                     DISIFFLVIGIMYFIITLILMTQVYGFFAVIFIIPFTIHIGYIVYKDELNQENVKNHF
                     MWIIVSYGISYLITQIALYGRIDANEIESIDILSVNAFFIIMWLLGQMAIWNFLFLRR
                     ALPLTKQELGEEEPELSRTSKGNVTNQTKIHLKQLQDKTTEYARKTRRSVDLDKIRAK
                     RDKFKKKVNDIIDIQEDDIPDWMRKPKWVKPMYVELFCGVVIFLFTFLEFNNRNALFV
                     YGDWKLSQTQYVIEWVTLLILLFIIIAYIATTLTFHLKGKFYYLQLFMGSILFFKLLT
                     EFINIMIHGLLLSVFITPTLLLMLLVIIISYSLQLRERP"
     gene            32198..>33288
                     /locus_tag="RPH49_001494"
     CDS             32198..>33288
                     /locus_tag="RPH49_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDY5124640.1"
                     /translation="MKIATLNKGKETKYFNGYPLIEEEDIYSQDHLKEGDIFQIVTDK
                     SQYVATAYVGRQHKGLGWVLTYDKAQEINTAFFVKLFNTALAERDYYFNIDGTNAFRL
                     FNAEGDGVGGLTIDNYDGHLLIQWYSKGIYKFKYAILEAVRKVFDYKSIYEKVRFKDS
                     EYSGGFVEGDAPEFPIVIEENFTFYNVDLEDGLMTGIFLDQKEVRKKLRDQYAKERHV
                     LNLFSYTGAFSVIAASEASSTTSVDLANRSRSLTEENFGLNAIDPKSQYIYVMDTFDF
                     YKYAARHGHSYDTIVIDPPSFARNKKRTFSVQKDYDKLITGALNILSSEGTLLLCTNA
                     SVYPLKQFKNTIKKTLEESGVDYELTEVMG"
BASE COUNT        11305 a         5036 c         5965 g        10982 t
ORIGIN      
        1 taattacgat cgcttatcac agtatgattt gacgatgaag attagcaggg aacaatctat
       61 agtttcaagg tggattaaga aattagtttt gaaagggtac atcacaagtc aacaatctag
      121 cgaagattta agatgtaaag aattaatttt gactgatcaa gcacgtacat taatttcaca
      181 aataaataat gcacgttgcg aattgattga agcaagatgt caatgtttat cggaagtcga
      241 attagataat ttaaatcaat tacttgataa gttaaatcaa cgacgcatat cgttgtaaca
      301 cgacaatagc aaacacataa tttagtgtca ttgtgcacac aacaaaaatt gaatcatgaa
      361 ttacaagcaa aagtagcggt gattgttaaa attgatggta aacaatcacc gctatttttg
      421 cttgtgtatg tataaaaaag ggatcaaagg tcatccccca tgattgatag tggggggatg
      481 acttttgatc ctatgttcat gttgcttatt tatattgtgg gatgtcgaag tatttgccga
      541 cttcgcccat tttatcatag tagcctttga tgattttagc attgatgtta gcccaatcta
      601 catctgtagc atattggtgt gttcctggat gtgcaggatt ccatctcatt ttgtaaagcg
      661 tattttgacc agcttttaca tatgagttgc cgatgaattt agcaccacca acgatggctt
      721 ttgaaactgt gtcccaacca gcttgtttag catatttaat accttcacgt aaaggatcgt
      781 tatcatatgc agcaatacca aatacgttat ggtatttcgt gttagagtta gttacaactt
      841 tgttgttcac tacatctgca ccttttgcta attgagaagt accgttacct gtttctaata
      901 gggcatgtga gataagataa acttcattaa tgccatacat ttgagcagct ttgttaaatg
      961 cagcaccttg gttttctaat acacctttac cttttaagaa ttgattaatt ttatcaatag
     1021 aaatattttg tggttggtct aagcgtaaga attgatattt taatgctgga tcttgagcta
     1081 aacgcttcgt atccattgca tgcttaacat cattaaagtt agcatctgtc cacttacctg
     1141 gtacacgttg tacttgtggt ttatattgta aaccagcttg aatttgagca acttggttta
     1201 atgtcatacc tgtttgatta tacttaatta attctttagc taaatcagtc gatttaatcc
     1261 atgctaattt accgttagat aatttaccat agtaccaagt ttgtccatta atgacttgtt
     1321 ctttaacaac tgagaatggt tgttcattaa atgcttttaa tgagtattta gctgtatcag
     1381 aatttggtgt tacatagtaa taaccattac catttttaat tacataagtg tagttataat
     1441 ctttggcagc tgatgtagtt ggtttaacag cagttggtgc agttaaatct tttgcattta
     1501 cccaaccagt gcggttatta atagtaccgt ataaataaac atctttgcct acagatactt
     1561 gtttcgctgc attaaatgta ccttgagcaa tgttattgcc tgttaaaatg acttggtttt
     1621 tagtacccca aggaaccatt gataagccgt tatttgattt attaacagta tatttttgag
     1681 tcgttttaac ttctttgcct aagttttgaa catttaagtc tttaacattg aaccaaccta
     1741 atggaatatt atgacttgta ttatttaata atacatatgt ttcattacca tgtgcacgtt
     1801 cttttgttac atagaatgta cgatccgcat attttgcgcc gtttttcgct gttttttcat
     1861 aaacagaagc acgaatacca gtgttgtttg gtttaacttg agcaattttg ctaactgttt
     1921 gagtcgtttg tggtttagta acagcataag cttttacagc tgtttttggt tgttctacag
     1981 cttttttagg tgcagcaggt acagctaaat atgctttact aatccatccg gatttaccat
     2041 ttacagttcc atataaatag atagatttat caatttgttg ttgcttagtc gctttaaaag
     2101 tttggttacc tgtgccagaa accgcaccag cttcttgttt ataagtaccc caaggtactg
     2161 aatataattt agtgcctggt tttactgtat atgtttgcat tacatttaca ggtgattttg
     2221 cattgttata aataacgtca ccttgtttaa cccaaccaat taaagttgga ctattgtaat
     2281 ctttaactag gtagaatttg tttccaccta gacttgcttc ttttgttaca gaaaatgttt
     2341 tttgaacttc tttcgttggc ttaccagttt tgtcataaac tgtagtgaat aaaccattgt
     2401 ttttagcatt aatttgagca acaccattta atgctgagac tgttaattta ttatttgttg
     2461 tcggcgttga tggcttaggt gttggtgcag gtgtaggttt agcagtatca actaaatatg
     2521 ctttacttac ccaaccagat ttaccattca cagagccata taaataaatt gatttatcaa
     2581 tttgttgttg ctttgaagcc ttaaatgttt ggtttccaga gccagacacg ctaccagcaa
     2641 cttgtttaga tgtaccccaa ggtactgtat aaagtttcgt accaggtttg attgaatatg
     2701 attgatttac atttacaggt gatttagctg tgttgtaaac cacatcgcct tctttaaccc
     2761 aaccaaattt attaccagaa ttgtaatctt gaacgagata gaatttttga ttacctaatg
     2821 tagctgtttt agatacagca aatgtttttt gaacttcatt agttgcctta ccagttttgt
     2881 cgtaaacagt agtatataaa ccactatttg ttggtttgat ttgtgcgaca ccattattag
     2941 catcaactgt taatttacca gttgatggtg ttgatggttt cgacggtgtt gttggttttg
     3001 atggtgtagt aggggtagtt gtagattgcg taccccatgg cgccacttta cccattttta
     3061 ttaaatattt ttcattaatt aagtcatata attgatcata actataatta tgacttctta
     3121 aatatccatg tggatcggca tggtccgtac cacctaaata tttacttaca gcgtagtgag
     3181 tccatactgt accatttcca tcatactcag cactgtctgg ttttaaacca taatattgta
     3241 attgtgtagc tgcatagtca gcatagttat tcattgaacg tgcaaatgaa gcataatcgt
     3301 gtgtgtgtac gatttcaaca ttgatgaatc tagggttacc gactgcacct acaccccatg
     3361 ataagtaatc cgttggtgct gtttcaatta tacgatcccc atcaacaaac gcatgaacga
     3421 aagcattttg ataattgttt ttcatataac taatttcgcc atttatcgtc gaacgatcat
     3481 tagctgtatc atgaactacg attccttcag gacgacctac gccgttacgg tatgcgtatt
     3541 tagggaagta agatgtataa tcttcttcaa tcttaggtgc ttttaaatta tttttacgaa
     3601 tgtaatcgtt aattgatgag tttacttgcg gtttatattt tggcaaactc gtttttggtg
     3661 ctgcagcgac tgatcttggt tgtgctgaag cactaaaagt agttactttt ggtgtagctt
     3721 cagttttagc tttaggtgca acaggtgttg cttttggtgc tgcggcttta tattgcgttt
     3781 caagagcagc aggtttagca gctgatttaa ttaattctgg atttatttga ttttctgaat
     3841 tatcatcttc atcatcaact aaactatatc cagcacttgt aacattattg ttcgttttag
     3901 atgctgttgt gttagttgtt tttgtaacag gtttcgcatt atttgatgta gttgattgag
     3961 tctcacgagt gtcaccattt acttgtgtag tatcaacctt ttgatttact tgagcattgc
     4021 ctgttttatt cgctgctttt ggttggacaa tagcagggtc ttgatatact tgagtgccag
     4081 aaatgttttg cgttggattt tttacctcag cttttgcttg ttcagtagtt gctttaactt
     4141 tattactatc taaaacgttt ttattagtag tttgatcttg tgtcgtctca gctgcttgaa
     4201 cttgatgtgc agtgactgct gaacctacaa gcgttaatgc aaccattgat ggtagtttgt
     4261 aattaaattt tttcgccatt ctatttatta ctcctaacat ttattaatta ttaatctcat
     4321 tatagtacct gttttataca cctgtgcgta tttaaccaat ttgtaatata ctcttaattt
     4381 atattttcac tgtaaaaaaa tgaaaaaaat tttgaatctc aatggtgacg tgacaaatca
     4441 aatagaattg atgtcaattt aagaattggt ttattacaaa tgtttctata atagatacaa
     4501 ctttttttaa ttaagcgagg tcaacttttt tgtcatttca atatgctcga tgccttcctc
     4561 aagaaatata ttacctctca ttttaaaatt taaactttca tagaatggaa ttgcatgaca
     4621 ttgggcattc atggtagcta cgtaaaaacc ttcatctata gctaatgact ctacagcttg
     4681 cataagcatt ctacccatgc cttgtccgcg atgtgatttc atcacagcta ctcgttctat
     4741 tttgacagtt gtttcattaa tagggcgtat tcgagcagtg gcaactggct gcccattgtc
     4801 atacccaatc aggtgaatag attcagattc atattcatca atttcacttt cctctgggac
     4861 gccttgttct tctacaaaca ctttctttct tatatagaag caatcttcta acatcttttg
     4921 attgtttact tttaaaaaca taaaatccct ccatatccca acaaaatcat ttatatttaa
     4981 tttactaata ataacataga ataacgattg ttatttttca caaaaataat tagacataaa
     5041 aaatgctata aaaatgattc ataggaacca tctttatagc tagatagagt gtatttgtta
     5101 taatgcttct tttctaataa ttgctgtata ttgccaaaag attcgcattt gagcaatatt
     5161 ccaattattc atccccattg taaacccaga aggtttaaag atatttacat ctgtcacttc
     5221 taaagctgct gcgactaaat attgtaatgg aatactaagt gatttcattg tttcagtaat
     5281 gccattttca tcatataccc atgaaaatgg taactctgat tcgaaaacat caacactatt
     5341 gaaaatttca ggtagggcta aaatataaca tgcaccatct acaataggat tctcgatact
     5401 atttttgtaa taaattagga gtgcttcata gttttctcga tgctcatgat tgacgtaaaa
     5461 aaattcactt ctaaaatgag ccatatcttg gctatgaata atttgttgtt ctaacatatt
     5521 aaacatccca tttatatttg caatcttttc gtatgttttt ctactcatgt atgatgctcc
     5581 tttcataaat agtaaatgtt aatcgtcata taatattagt ttacaacacc attttggtta
     5641 tttgaagctt gtggcgtttg ttgagtgcca ccttgatttt gatttaagtt ttgatctgta
     5701 gcaggttgtt gttgattatt gacgctattg ttgctattac tgttattact gtcgtcgcta
     5761 ttattcgaag atttatcttt atcagtcgta tcgttttgtt cttttctcaa taaactacta
     5821 tctaaaggcg ttaatggtat taatgaacca taatgattga tgacacgttg atctaagaaa
     5881 tcatttttat cattaatagg tgataattct aagtctttac gaagtaagtt tgcatatttt
     5941 tgaatgctgt ctacacttgg atgataatag taaataccat ttaacatatc atctttacct
     6001 tttaattgcg cagttttaat ttcaacatca tttgttaagt acatttttgc taaagcttta
     6061 atttcagagt tagttaaatt atgctttgca tttttaccta caatttgaat cacgttatca
     6121 agtttatcaa tagaatcaac ttcctgtgct ttttggaata aaatcttaat taattccatt
     6181 tgacgttgtc cacgtttcaa gtctgaatca tgatgtctag ttctagcaac tgctaaagcc
     6241 tcatcaccat ttaatttttg gtaccctttt ttaattttaa tcttaccagt atcatctgta
     6301 tttggctcat ttaaatcata tggtacatca tagtatatgc caccaagttc atttacagct
     6361 tctacaaagg ccttcatatt aacgcgtaca tagtaatcaa ctggaacatt catcgttgct
     6421 tcaacagagt ccattgctgc aattggacca ccatatgcat gtgcatgggt aattttatcg
     6481 tagtagccga ctttaggaat gtagctgatt gtatcacgag gaatactaag cattcgaatt
     6541 tggtgtttag attgattaaa agtagttaaa atcatagcgt ctgatctaga gtgttcagca
     6601 tcttggcctt tttttcttct tccgtcatta tcatcgatac ctaagaagag aatagagata
     6661 ggttgttctt caggattaac tttattgtct cgtaaatttg attgacgatt agcattttta
     6721 ctatcttgag aagattcaaa tgcatcttga gacgttttaa aaagtaacgt agcgaagaca
     6781 attggaacaa caataagaac caatgctaga aggatcaaaa agtattttaa aaatttattc
     6841 atgattgatg ctcctatatt aaatttttgt taaatcataa tcataatttt aaaatataat
     6901 tagttgaacg atatttatac aacttcatta ctaatacatt atagccttaa attgtagtac
     6961 tttatagtaa aaaatacaaa tgttatgtca aagttccttg taatttgaat gttttgttaa
     7021 aatcaaaaag cattttaaaa aatataatgc gactttagta tgatgtctaa aaaaaattaa
     7081 aggggtaata taaatttgag tgatttatac aatgtgataa ggtataatta aatttgttgt
     7141 aataagaact tatatgaaga aaatattact aagtagcata acgcataagt gggtgacaga
     7201 taaaattgta agtgatatta taacgaagtt aaggttattg ttttaattat ttaatttgaa
     7261 tacaatgaga ggctattagc gaatgaaatt taataaagtg aaattggtta tacatgcatg
     7321 cgtgcttttg ttcatcatta tctctatagg attagttttt catcgattac aaacgaaaac
     7381 gaactctata gaacctatac ataaggaaac aaaattatcg gataatgcga aatatttggt
     7441 tgatcgtaat aaaggcaaag gtgagccatc gaaattaaag gaagtataca atagtaaaga
     7501 tccaaagtat aagaagattg accagtattt acaaaattca ttatttaatg gttcagtagc
     7561 ggtatatgaa aatggcaaat tgaaaatgag taaaggctat ggatatcaag attttgaaaa
     7621 aggaattaaa aatacaccaa atacgatgtt tctaattggt tcagctcaaa aattttcaac
     7681 aggattactg ttaaaacagt tagaagaaga acataaaatt aatattaatg atccagtaag
     7741 caaatatatt ccatggttta aaacatctaa gcccattcct ttaaaagact tgatgctgca
     7801 tcaaagtgga ttatataaat ataaatcttc aaaagactat aagaacttag atcaagcagt
     7861 gagagcaatt caaaaacgtg gcattgatcc taagaaatac aaaaagcata tgtataatga
     7921 tgggaattat ttggtgctag ctaaagttat cgaagaagtt accggcaaat catatgccga
     7981 gaattactat acaaaaatag gggatcctct aaaacttcag cattcagcat tttatgatga
     8041 aaaatcattt agaaaatatt tagcaaaagg ttattcttat aatagtacag gactttcttt
     8101 cttgaagcct aatgttttag aacaatatta tggtgcaggt aatatatata tgacaccaac
     8161 agatatgggt aaattaatta ctcaaatgca acaatataaa ttatttagtc ctaaaataac
     8221 caacccatta ttacatgagt ttggtacgaa acagtatcca gatgaatatc gatatggttt
     8281 ctatgttaag ccaacattga atagacttaa cgggggattc tttggacaag tctttactgt
     8341 ttactataat gataagtatg tagttgtact tgcattaaat gtaaaaggaa acaatgaagt
     8401 tcgaatcaaa catatttata atgatatttt aaaacaaaat aaaccttaca atacgaaggg
     8461 tgttattgtt caataattaa tatagaagat ataacttgta tatggcatta aggcattgac
     8521 cttatttgac tagtatacga gttatatctt cttttttata gaggtgaaaa gtttaaagta
     8581 taaggttgaa gtagtaggat gataaatttg cgttaagtta aaaagatata aacaattgat
     8641 gtaaatgtca atataaaaat gtatataaat gattgtataa gaatgtatta attgaatgga
     8701 taataatgat tgtcttttaa gatatagaag gggacttaac catttaaaaa ttgaaggaaa
     8761 ataaaaacca gctaacaaaa gtgttagctg gttaaacttt acattattaa aatgttgttt
     8821 ataagtgtga agagtgaccg ccttgcataa cccaatatgt tccgacaacg aaacaaagtg
     8881 taattacaag agcaaagata actttgaatg tttgtaaacg tccatcttta ccttcagtta
     8941 aatgcatgaa cattaataat tgaagtccag cttggatgaa tgcaaagcca aagataattg
     9001 tcaacttcgc gtggaatgtt aatgacgtgt atagtgttac gtaaactgct aaaagcgtta
     9061 atacgataga tgcgataaat cctacagtat gtttcattat tgtactcatc cgctatacac
     9121 catccctatc atatatacgg cagtaaagat gaaaacccaa acaacatcta agaagtgcca
     9181 gtataaactt actataaata attttggcgc attatatttg tctaatccgc gtcgttggat
     9241 ttggattaat aaacaaatgg cccaaacgat acctagcgat acgtgacaac catgcgttcc
     9301 taataggata aagaaactag accagtaaga accaattgtt gggttaacgc cttctgatgc
     9361 atagtgtgcg aattcataaa tttcgaatcc aacaaagact aaacctaaaa gtaacgtaat
     9421 gatcatccaa aacatcatta acttttgttt ttcttggcgc atgtagtaaa tagcaatacc
     9481 acatgtgtaa gaactgaata ataatgcaaa cgtcattatt aaaacaagag gcaattcaaa
     9541 taactcagta gtcattttac ctgcataatc gccaccatgt tgcaaagtta atagtgtcgc
     9601 aaatagggta ccgaataacg caaattcggc tgtaatgaaa atccaaaagc caagcttatt
     9661 taattcgcct tcatgtgtgc gtgaatcaat agtgtttgta tcatgactca tgacttacag
     9721 cctccctttc tttaatacgc gcttctctta atctagcttc agtttcagca acttcagcag
     9781 cagggatatg atatccgtga tcgatttgga aactgcgata aatcatagta ccaaaaatac
     9841 cgaataaaca aattaatgct ggaattacag tttcgaaaat taagaagaaa ccgccgatag
     9901 tcataaagat accaatccag aatccaacag gagtattgtt tggcatatga atgtctttgt
     9961 aattatggtt gtctaagtaa tgacgaccat gttctttcat atcaacaaat gtgtcgtagt
    10021 cattccaatc tggtgtaatg gcaaagttgt atttaggtgg aattgctgat gcagtagtcc
    10081 actctagagt acgaccaagg ccatcccagt tatctccagt tgcttcacgt ggagatttga
    10141 agtgactgta tacgatacta acaacaagga ataagaatcc gattgccatt aataatgcac
    10201 cgatagttga aattaagttt aataagaacc aaccatctga tggcatataa gtgtataaac
    10261 gacgtggcat accatctaat ccaagaatga attgtggtaa gaaacaaacg ttaaatccga
    10321 tcatgaagaa ccagaagcac catttgttta atgtttcgtt taatttgtaa cccatcatct
    10381 ttggatacca gaagattaaa ccagctaagc aggcaaatac aacaccagta accaatgtat
    10441 agtggaagtg agctactaag aagtacgtat tgtgatattg atagtcagct gatgccattg
    10501 ctaacattac acccgtaaca ccacctaaaa ggaagttagg gataaatgct aatgagaata
    10561 gcattggtga ctcaaatgta atacgtcctt tatataatgt taataaccag ttaaacaatt
    10621 tcacaccagt tggaatacca atcagcattg ttgaaattga gaagaatgag ttgattaacg
    10681 caccattacc cattgtgaag aaatggtgaa cccaaactaa gaaactaagg aacgcgatac
    10741 cggcagttgc ccataccata ctttgatgtc cgaataaacg cttacgagcg aatgtcggga
    10801 taatttctga gtaaatacca aatgctggaa ggataacgat ataaacttca gggtgccccc
    10861 atacccagaa gaagttagcc caaagcattg gcataccgcc atgtgcaact gtgaagaatg
    10921 ctgtgtcaaa tattctatca gttgtcatta atgctaacgc tactgttaaa ggagggaaag
    10981 caagaataac aattaatgta gtaataaatg ttgttactgt aaacattggc atttgcataa
    11041 acttcatagt tggtgtttta catcttaaaa ttgttacaaa gaagttgata cctgtagcta
    11101 aggtaccaag ccctgaaatt tgtatagcta ttaagtaata gttaacaccc ggaccaggac
    11161 tgaattcacc tgctagtggc gcatagtttg tccaaccagc tgctggtgaa ccaccaataa
    11221 taaatgacag gttgaataaa atcatacctg caaagaatag ccagaaactt acgttgttta
    11281 atactgggaa tgcaacatca cgtgctccaa tttgtaatgg aacaacgata ttccataaac
    11341 caaagataaa tggcattgcc atgaagataa tcatgattac accatgtgta ctaaaaattt
    11401 cgttatagtg gttagattct aaaaatttgt tatcaggtac tgttaattgc gcacgaataa
    11461 gtaacgcatc aataccacca cggacgaaca ttaatacggc acagattaaa tacataatac
    11521 cgattttctt atggtctaca gatgtgaacc attctttgta aagatatttc cataatttaa
    11581 agtaagtaat tactgcgatt aaaccaataa ctaagaatgg ggcaccaatt tgtgccattg
    11641 taatcatcca gttaccttta actagtaatt gatcccatgg aaaattcatt aatgtccacc
    11701 tccatgatca tcattgtctt gatcttgcgc atcttttgaa attttcttca tttctttcgc
    11761 atttttcgat tcatctttct tgaactcatt gttatatggt tcgtcatttc caagaatcat
    11821 caatttcata ccatgtcgtt tatagttcgc atttgtaatt tgagctttac gagcaggtat
    11881 taatggtttg tctgatacat ctttaaacat attttcttca ctagtgaagt ttggatcttt
    11941 caattcgaaa ttgaaacgtt tatatgcata gaagatgtat tctggatcgg ctgctggatc
    12001 aacaaacgcc atatgtgtac cattaaattc taaagcttta ttaggtgtgc ttggtaataa
    12061 ttgtttatca aatgtatctt gatctaacgt tttcttacct ttaacttctt tcacccattt
    12121 gtcgtagtct ttttgactaa cggcatttac tttaaatgtt tgacgtgaga atccttcacc
    12181 attgaagtta gagttacgac ctctgaacgt accagtttga gatgcttcta acgtccaatt
    12241 cattgtcatg ccagtcatgg catatttttg accacctaat tgtggaatcc agaaacttgt
    12301 cattgtatcc atagcttgaa gcttaaatac aacaggacga tctttaggga ttgttaatgt
    12361 attaacagtc tctatatgtt catctggata agcaaagaac catttgtatc ctgcacttac
    12421 tgcatataca accattggat ctttctcact cttcggtggt ttttcgtaat cgtataaagt
    12481 tttaactgta ggaatagcta aagcagcaac gattatgata ggtattacaa accatattgt
    12541 ttcaatgatg gcattatggt gcatcttacc agattcggca ttcttattat aactatactt
    12601 gtaaataaaa atggcgaaca tgccaagtac aacgaaacaa ataacaagca tgaagacgat
    12661 tgaataaaga atcaagaact tctgactact tgctactggc ccttttgcgt tgaaaatttc
    12721 tatatttgaa caaccactaa gtaaaattag tgtgccaaat aatagaagca aagacttaaa
    12781 ttttgacact tttttgacct cctaatacta caaatgtagg gcttaacatt aattttaagt
    12841 tattacacaa tatttacaag ggcttatggg aaaaaaatta ataaaattgt atcaaaaatg
    12901 ttgataaatc aaggtgtgac gtgggttcac acatttgtta aaattatgtg tacattttgt
    12961 gactaatagc gtttttgaaa aaattgcttc atatttaaaa gggaagttga gaatagcttt
    13021 caattaaagg ttaattgaat gaaaataaaa aaagtttgaa attgtctaat aaattgaaaa
    13081 tgatggctag ttcattgaaa ggaagcgcaa acattttaat aaggaatttg ccaaaagtaa
    13141 tttatcgtta aacaatgaaa agtagaaatt tgtttgttca aaatcaaaat attcttttaa
    13201 aaagagcagt taagttttaa taatttgaaa ggtagtcctt tggtatacag aaaaaataca
    13261 atatttgggt taaagttgca gatgaagttg gaataacaaa taaaatggta gcaaaacatg
    13321 tacgtttgct accattttat ttgcagtata gtgatgaggg ctatttaacc tcaatatacc
    13381 tagtggaaat tttaattgca ccatctgaat cagtgacatg atatttaatt tgatatttac
    13441 cagatttaga tgtatcaatt tggccatcga ctttaatttt atcggttaaa tctccatctt
    13501 ctttatcaaa tgcacttatg ccgtttagaa ggttataatc ttgacctttc ttaataacga
    13561 tatcattagc gcctttaatt tgtggtgtag tattcgtcgt tgcatctgca tttaaatttg
    13621 gtgttactag tgtagcagaa acaccgaggg ctgataatga ctgtaatagt ttattcataa
    13681 tgtaacctcc gaatgataag tcatttctga gttagcttta ctatacctta atttatatta
    13741 tttacacatc atactatagt cctaatctta ccctataaag aatgaaattt aaatataaat
    13801 ttataaataa tgaggaaata attattattt tgaaaatctg ccacaattgt aaaattaata
    13861 attcagggat aatttgaaat caaatataac tttattcgac agtttgaaca taaatttttg
    13921 tgtatcaaaa caataagaaa agggaggcga aaatgataaa gaaccactat tgattaatta
    13981 tgtagtagta ctttatcata gtcacagctt ctgtgatggg gcctcgtcga cttgcattgt
    14041 ctgtagaaat tggaaatcca attcctcttt gttggggccc atccccaact tgcacattat
    14101 tgtaagctga ctttccgcca gcttctatgt tggggccccg gactataatt gaaaaatgct
    14161 tgttacaagc ttattttcat tcaattaaca actgtctata taaaattgtt gagccaagaa
    14221 caaagtgaaa tgctcccttc aaagccttca tttattcaat gtctactttg aagggagcat
    14281 ttgatcgatt aatgtcccag atttttcttg ttattcattc acattacatg actaatgtga
    14341 atttacgaat caatacctcg acgcattttt tctgcaagca aagtattatt taataccata
    14401 gtaattgtta atggaccaac gccaccagga actggtgtaa tagctccagc aatttcttta
    14461 accgcatcat aatcaacgtc accttttaat ttcccatttt catctggcgt attgccaaca
    14521 tcgataatta ctgctccttc tttgaccaca tcttttgtta ctaaaccagg cttaccaact
    14581 gcactgacaa tgacatcagc atcttttaaa tatgatgcca tatcctttga acgagaatgt
    14641 aagattgtta ctgatgcatt tttttgaagt agtaacttag aaactggttg tccgacaata
    14701 tgacttcgtc caattacaac tgcattttta ccttctaaat caatatcagc atgttttaat
    14761 atttccatga tgccgagcgg tgtgcaaggt acaaaagttt gttcatcgat atataatttc
    14821 cctatattta ttggatgaaa accgtccaca tctttatcag gattgattgc ttctaatatt
    14881 ttctgttcgc taacttgttt tggtagtggt acttgtacca aaataccact tacagaatca
    14941 tcattattta gtctatttag ttcgtttaat acttcctctt cagtagctgt ttcttccaaa
    15001 tgtacgattt ctgaaatcat accaattttt tcagctgctt tcttttttga tctaacataa
    15061 ctttgactag cgccatcatt accaactaat ataacggata atttaggtgt aaaacccttt
    15121 tcttttagcg cttcaacttg atcttgtaac ccctgtctgt agtctttggc aatttgttta
    15181 ccatctaaaa ttttagcaac cataaaaact tctcctccta ttgtcaatat cctaactttg
    15241 ttagtttata aaactaattt acatagcaaa agacgtaaat tcaaacaaaa aatcaaaata
    15301 aagttcgatt tttgattgaa aaagcagaaa ttgcttgtta tgctatatct ataatataca
    15361 actaaagtaa ttcacaattc aaacttttga aagggtgtac aaagtgaaag tagcagtcat
    15421 tatgggcagt tcttccgatt ggaaaattat gcaagagagt tgtaacatgt tggattattt
    15481 tgaaattccg tacgaaaaac aagtagtatc ggcacatcgt acgccaaaaa tgatggttca
    15541 atttgcttct gaagcgagag aaagcggtat agacattatc attgcaggcg ctggcggtgc
    15601 ggcacattta ccaggtatgg ttgcatcatt aacgacgcta ccagttattg gagtgccgat
    15661 tgaaacaaaa agtttaaagg gtatagattc tttattatca attgttcaaa tgccaggagg
    15721 tattccggtt gcaacgactg caattggtgc agcaggtgct aaaaacgcag gtatacttgc
    15781 agcaagaatg ttaagtattc aaaatccttc tttagttgaa aaactaaatc attatgaatc
    15841 ttcgttaatt caaaaagtgg aggacatgca aaatgaactt caataaatta aagtttggtg
    15901 cgactattgg cattattggt ggtggtcagc ttggaaagat gatggcacaa tcagctcaaa
    15961 aaatgggtta taaagtggct gtattggatc ctgctgaaga ttgtccatgt agatacgttg
    16021 cacacgaatt tatacaagcc aagtatgacg atgaaaaggc actcaatcaa ttaggacaaa
    16081 aatgtgatgt gattacttat gaatttgaaa acatttcagc ccaacaatta aaactattat
    16141 gtgaaaagta caatattccg caaggttacc aagctataca gttattacaa gaccgcttaa
    16201 ctgaaaaaga aacattaaaa agtgctggta ccaaagttgt cccgttcatt tcagtaaaag
    16261 aatctacaga tattgacaaa gcaattgaaa cattaggata tccttttatt gtaaaaacta
    16321 gatttggtgg ctacgatggc aaaggtcaag ttttaattaa caacgaaaaa gacttacaag
    16381 aaggttttaa attaattgaa actagtgaat gcgtagctga aaaatatttg aatatcaaga
    16441 aagaagtatc acttactgtt acaagaggaa acaacaatca aattacttat ttcccattac
    16501 aagaaaatga gcatagaaat caaatacttt tcaaaacaat tgttccagcg agaatagata
    16561 aaacagctga ggcgaaagag caagttaata aaattatcca atcgattcat ttcattggaa
    16621 catttacagt tgaatttttt atagatagta acaaccaatt gtatgtgaac gagattgcac
    16681 caaggcctca caattccgga cattattcaa ttgaagcatg tgattattca caatttgata
    16741 ctcatatttt agcagttacc ggacaatcat taccaaattc aattgaatta ttaaagcctg
    16801 cagtcatgat gaacttacta ggtaaagact tagatttatt ggaaaatgaa tttaatgaac
    16861 atccagagtg gcacttacat atttatggta agtctgagcg taaagatagt agaaaaatgg
    16921 ggcatatgac tgtactaacg aatgatgtaa accaaactga acaagatatg tacgctaaat
    16981 ttgaggggag taattaaagc atgacattat tatatgaagg aaaagcgaag cgtattttct
    17041 caacaaatca agaaaatgaa ttaagagttg aatataaaga tgaagttact gctggaaacg
    17101 gggctaagaa agacacaatg gcaggtaagg ggcgattaaa taatcaaatt acttctatta
    17161 tatttaaata tttacaagaa aatggaatag aaagtcactt tattaaacaa ttatctgaaa
    17221 cagatcaatt agttaagcct gtgaaaataa ttccattaga agtagttgtc cgtaatattg
    17281 ctagtggatc tattacaaag cgtttaggtt ttgaaaatgg tgaagttttt agagaaccac
    17341 ttgtggaatt tttctataaa aatgatgcat taaatgatcc tttgattaca gatgatcaca
    17401 tcaaattact gaatattgcg acagataaag atattgaaac attaaaaacg aaagcgctag
    17461 aaattaatca agtattaaaa caattaatgg atgcgatgaa tttaaaatta gtagatttta
    17521 aaatcgaatt tggaaagact gagactggtc aaattttgtt agcggatgaa atatctccag
    17581 atacatgtcg aatttgggat aaagctacca atgcaaactt tgataaagat gtatatagaa
    17641 ataacactgg atcactgatt gaaacatatc aaatattttt aaacaaattg gaggatttaa
    17701 aataatgaaa acaattgaac tacatatcac attacaacca caagtattag atacgcaagg
    17761 acaaacgctt actcgagctg tacatgactt aggttatgca caagtgaatg atattcgtgt
    17821 aggaaaagta ttatatatga cagtggatga ggttagtgat gaaaaggtac acaacattat
    17881 tacaactcta agtgaaaaat tgtttgcaaa tacagtgatt gaagaatata gctataaagt
    17941 gttagatgat gaaaaggaga atgcataaaa tgaaatttgc ggttcttgtt tttccaggtt
    18001 cgaattgtga tagagacatg tttaatgctg ctattaaaag tggtgttgaa gcggaatatg
    18061 tagattatag agaaacatca ctaagtggat ttgatggcgt acttattcct ggtggatttt
    18121 cattcgggga ttacttaaga tctggggcaa tggctagtgt agcgccgatt atttcggaag
    18181 ttaaacgtct tgcagctgaa ggtaagccag tattaggtgt ttgtaatggg tttcaaattt
    18241 taactgaaat aggcttatta cctggtgcat tattgcataa cgattcacat ttatttatta
    18301 gtagaaatga aaagttagaa atagtgaata atcaaacggc atttacaaat ctttatgaac
    18361 aaggtgaaaa agttatatat cctgtagctc acggtgaagg tcattattat tgtactgatg
    18421 aaatatatca acaattaaaa gctaacaatc aaattattct gaaatatgtg aataatccga
    18481 acggttcata tgatgatatt gcaggaattg ttaatgaaaa aggcaatgta tgtggcatga
    18541 tgccacatcc tgaaagagct ttagaaacgt tgttaggtac tgatagtggt gtgaaattat
    18601 ttgaagcgat ggtaaaaagt tggagggaac aacatgtcta aatttatcga accaagcgtt
    18661 gaagaaatta aacttgaaaa agtatatcaa gatatgggat taagtgatca agaatatgaa
    18721 aaagtttgcg atattttagg cagacaacct aactttacag aaacaggtat cttttctgtt
    18781 atgtggagtg aacattgctc ttataaacat tctaaaccgt ttttaaagca atttcctacg
    18841 tcaggtgagc atgtgcttat ggggcctggt gaaggtgcag gggtagtcga tataggtgat
    18901 aatcaagccg tagtatttaa agtagagtct cacaatcatc catcagcaat tgaaccatat
    18961 caaggggctg ctacaggcgt tggtggaatc attcgtgaca ttgtctctat tggggctaga
    19021 cctattaatt tgttaaacag tcttagattt ggagaattag ataataaaca aaaccaaaga
    19081 ttacttaaag gtgttgtaaa gggtatcgga ggttatggta actgcattgg tattccaaca
    19141 actgctggtg aaatcgaatt tgatgaacgt tatgatggca atccacttgt taatgcaatg
    19201 tgtgttggtg ttatcaatca cgacatgatt caaaaaggca cagcaaaagg tgtaggtaat
    19261 tcggtcattt atgttggttt gaaaactggt cgagatggta ttcatggtgc tacttttgca
    19321 tctgaagaat tgacggaaga aagcgaaagt aaacgacctt ctgtacaaat cggtgatcca
    19381 tttgtaggta aaaaattaat ggaagcaaca cttgaagcaa ttacatttga tgaattagtt
    19441 ggtattcaag atatgggtgc tgctggttta acatcttcat cgtctgaaat ggcggcaaaa
    19501 ggtggtagtg ggttacattt gagattagaa caagtgccaa cacgtgagcc aggtatttct
    19561 ccttatgaaa tgatgctttc agaaactcaa gaacgtatgt tactagttgt tgaaaaaggt
    19621 actgaacaaa aattcttaga tttatttgat aagcacgaat tggatagtgc tgttataggt
    19681 gaagttacag atacaaatcg ttttgtttta acatatgatg acgaagttta tgctgacatt
    19741 ccagttgaac cactagctga tgaagcacct gtatatattt tagaaggaga agaaaaagat
    19801 tataatactt ctaaaaatga ttatacacac atcgatgtta aagatacttt ctttaaatta
    19861 cttaagcatc cgactatagc atctaaacac tatttatatg atcaatacga ccaacaagtt
    19921 ggtgccaata cgataattaa gccaggactt caagcatcgg tagtacgtgt ggaaggcaca
    19981 aataaggcga ttgcttcaac aattgatggt gaagcgcgtt atgtatataa caatccatat
    20041 gaaggtggaa agatggtagt agctgaagct tatcgaaatt taattgccgt gggtgcaaca
    20101 ccattagcaa tgacagattg tttaaattat ggttctcctg aaaagaaaga aatctatcaa
    20161 cagttgatag attcaacgaa aggtatggca gaagcatgcg acattcttaa gacaccagta
    20221 gtttctggaa atgtatcttt atataacgaa acgaaaggta cttctatttt cccaacacca
    20281 gttgttggaa tggtaggttt gattgaaaat gtaaattatt taaatgattt tgaacctcaa
    20341 gttggagata aattatattt aatcggtgat actaaggacg actttggtgg tagtcaactt
    20401 gaaaagttaa tttatggcaa agttaatcat gaatttgagt cattagattt gagttcagaa
    20461 gttgaaaaag gtgaatcaat caagaccgct attcgtgaag gactattatc acatgttcaa
    20521 acagttggta aaggtggctt actgattacc ttagctaaac taagtgcgca ttacgattta
    20581 ggattaaaat cttcaataga tataacaaat gcacaattgt ttagtgagac acaaggccga
    20641 tatgttgttt ctgttaaatc aggtaaaact ttaaatattg ataatgcaat agaaattgga
    20701 cttttaacag atagtgataa tttcaaagta acaacaccat atacagagat tagtgaaaat
    20761 gtttcagata ttaaacaaat atgggaaggg gcaattgctc aatgtttaac tactcaggat
    20821 taaacgaaga atgtggcgtg tttggtattt ggaatcatcc tgaagcagcg caactaacat
    20881 atatgggact tcatagtttg caacatcgtg gtcaagaagg tgcaggtata gttgtttctg
    20941 atcaaaatga attaaaaggc gagcgaggat taggcttact aactgaagcg attaaagatg
    21001 atcaaatgga acgattaaaa ggatatcaac atgcaattgg tcacgtccgt tatgctactt
    21061 caggtaataa aggtattgaa aatattcaac cgtttctgta tcacttttat gatatgagtg
    21121 taggtatttg tcataatggt aacctcatta atgctaaatc attgcgtcag aatttagaaa
    21181 aacaaggtgc tatcttccat tcgtcttctg atactgaagt cattatgcat ttgattcgac
    21241 gcagtaaggc accaactttt gaagaagcat taaaagaaag tcttcgaaaa attaaaggtg
    21301 gttttacatt tgcaatttta acaaaggatg cgttatatgg cgcagtagat ccaaatgcta
    21361 tcagaccact tgttgtaggt aaaatgaaag atgggacata catccttgca agtgaaacat
    21421 gtgcaataga tgtgttaggt gcagaattcg ttcaagatat tcatgcaggt gaatatgtcg
    21481 tgattaacga taaaggtatt acagttaaat cttatacaca tcatacgaca actgcaattt
    21541 ctgcgatgga atatatttat tttgctagac cagactcaac aatagctggt aaaaatgtcc
    21601 atgcagtacg taaagcttct ggtaaaaaat tagcccaaga aagccctgta aatgctgata
    21661 tggtcatcgg tgtacccaat tcatcgttat cagctgcgag tggttatgct gaagaaatag
    21721 gtttgccata tgaaatggga ctagttaaaa atcaatatgt tgcaagaaca tttattcaac
    21781 caactcaaga attacgtgag caaggtgtga gagtgaagtt atctgcggta aaagatatag
    21841 tagatgggaa aaatatcatt cttgttgatg attctattgt tcgcggtacg acaattcgac
    21901 gcattgtgaa aatgttaaaa gattctggtg caaataaagt gcatgtgcgt atagcatcac
    21961 cggaatttat gttcccaagt ttttatggaa tcgatgtttc aactacggca gaattaattt
    22021 ctgcaagcaa atcacctgaa gaaattaaag attatattgg cgctgattca ttagcatatc
    22081 tatctgtaga tgggttaatt gaatcaattg gtttagatta tgacgcgcca tatagtggct
    22141 tatgtgtaga aagtttcact ggagattatc ctgcagggtt atacgattat gaagcaaatt
    22201 ataaagcaca tttaagtcat cgacaaaagc aatatatttc taaaaataaa cacttttttg
    22261 atagtgaggg aaatttaaat gtctaaagca tatgaacaat ctggtgtaaa tattcatgct
    22321 ggttatgaag ctgtagaaag aatgtctagt catgttaaac gtacgatgcg taaagaagtt
    22381 atcggtggtt taggtggatt cggtgctaca tttgatttat cacaattaaa tatgacagca
    22441 ccagttttag tttctggaac agacggagta ggaacgaaat taaaactagc tatcgactat
    22501 ggtaaacatg attcgatagg tatcgatgca gtcgcaatgt gtgttaatga tattttaacg
    22561 acaggtgcag aaccattata ttttttagat tacatcgcta caaataaagt tgttcctgaa
    22621 gttattgaac aaattgttaa aggtattagt gatgcatgtg ttgaaacgaa tactgcactt
    22681 atcggtggag agactgctga aatgggtgaa atgtatcacg aaggcgaata tgatgtagcc
    22741 ggatttgctg ttggagcagt tgaaaaggat gactatgtag atggttcaga agtgaaagag
    22801 ggacaagttg ttataggact tgcgtcaagt ggcattcatt caaatggata tagtttagtg
    22861 cgcaaattaa ttaatgaatc aggcattgat ttggcatcaa acttcgataa tcgtccattt
    22921 atagatgtct ttttagaacc aactaaatta tatgtcaaac ctgtacttgc tttgaaaaaa
    22981 gaagtttcta ttaaggcaat gaatcatatt actggtggag gtttttatga aaatattcca
    23041 cgtgcattgc cagccggata tgctgctaga attgatacta catcatttcc aacgccaaaa
    23101 atatttgatt ggttacaaca acaaggcaat atagatacaa atgaaatgta taacattttt
    23161 aacatgggta ttggctatac ggttatcgtt gatgaaaaag atgcatcacg cgctttgaag
    23221 attttagcag aacaaaatgt ggaagcctat caaattggac atattgtgaa aaatgagtca
    23281 actgcaattg aattgttggg ggtataacaa tggttaaaat tgcgattttt gcatcaggtt
    23341 caggaagtaa ctttgaaaat atagttgagc atgttgaatc aggaaaactt gaaaatattg
    23401 aagttacggc gctatatacg gatcatcaaa atgcgttttg tatagataga gcaaaaaagc
    23461 acggtattcc tgtttatatt aatgaaccaa aacaatttga ttcaaaagca gcgtatgaac
    23521 aacatttagt aacattatta aataaagata aggtagagtg gattatttta gctggttaca
    23581 tgcgtctaat tggtccagat ttattagctt catttgcagg taaaatattg aatatacatc
    23641 catctctatt gccgaaatat aaggggattg acgcaatagg ccaagcatat catagtggcg
    23701 atactattac tggttcgaca gtacattatg ttgatagtgg tatggatacg ggagaaatta
    23761 ttgaacagag aaaatgtgat attagaccgg acgattcaaa agaacaatta gaagagaaag
    23821 taaaaaaatt ggaatatgag ttatatccaa gtgttattgc taaaattgta aaataaggag
    23881 tatgtatgtg atgaagaaag ctattttgag cgtatcaaat aaaacaggta ttgtagagtt
    23941 tgctaaagcg ttaacgcaat taaattatga attatattca acaggtggta ctaaacgtat
    24001 attagatgaa gcaaatgtac cagttcgttc tgtttcagac ttaacacatt ttccagaaat
    24061 aatggatggc cgtgttaaaa cattacatcc ggctgttcat ggtggcattt tagctgatcg
    24121 aaataaaccg cagcatttaa atgaattatc agaacaacat atagatttaa ttgatatggt
    24181 agtagttaat ttatatccat tccaacaaac tgttgcaaac cctgatgtga cgatggacga
    24241 agcaattgaa aatattgata ttggtggtcc aacaatgtta cgtgctgcag ctaaaaacta
    24301 taaacatgta acaacaattg tacatccggc agattatcat gaagtattga cgcgattaag
    24361 aaacgattcg ttagatgagt catatagaca atcattaatg attaaagttt ttgagcatac
    24421 tgcagaatat gatgaagcga ttgtacgttt ctttaaaggg gataaagaaa ctttaagata
    24481 tggagaaaat ccacaacaat cagcgtattt tgtgagaact tcgaatgcta agcacacgat
    24541 tgcaggcgct aaacaattac atgggaaaca attaagctat aacaatatta aagatgcaga
    24601 tgctacacta gctttagtta aaaagtttga tacacctgct gcagttgcgg ttaaacacat
    24661 gaatccatgt ggtgttggta tcggtgacac gatagagcaa gcatttcaac atgcgtatga
    24721 agcggatagt caatcaatat ttggtggaat tgttgcatta aaccgagctg taacacctga
    24781 gttagcagag caattgcata gtatcttttt ggaagtcatt attgcaccaa aatttacaga
    24841 tgaagcatta gatattttaa aacaaaagaa gaatgtaaga ttattagaaa ttgatatgac
    24901 tatagacagt aacgaagaag agtttgtttc agtatctggc ggatatttag ttcaagataa
    24961 agataattat gtcgtaccaa aagatgaaat gaaagttgtt acagaagtag tacctacaga
    25021 tgaacaatgg gaagcaatgt tattaggatg gaaagttgta ccatcagtaa aaagtaatgc
    25081 aattatttta agtaataata aacaaactgt aggtataggt gctggacaaa tgaatcgtgt
    25141 cggtgctgct aaaattgcgt tagagagagc tattgaaatc aatgatcatg tagcgttagt
    25201 atctgatgga tttttcccta tgggagatac agttgaactt gcagcacaac atggtataaa
    25261 ggcaattatc caaccgggtg gttcgattaa agatcaagat tcaattgata tggctaataa
    25321 acatggtatt gcaatggtag tcacaggcac tcgacatttt aaacactaat tttaaagggg
    25381 cgtaacataa atgaatatat tagtaattgg tgctggtgga cgagaacatg cacttgcata
    25441 taaacttaat caatcgaatc tagttaaaca agtgtttgtc attccaggta atgaggcaat
    25501 gacacctata gctgaagtac acactgaaat ttcagaatct aatcatcaag ggatactaga
    25561 ttttgctaaa cagcaaaatg ttgattgggt agttataggt ccagaacagc cgctaattga
    25621 tggattagca gacattttac gagcgaatgg tttcaaagtg tttggtccaa ataagcaagc
    25681 agctcaaatc gaaggctcaa aattatttgc taaaaagata atggaaaaat ataatattcc
    25741 aactgctgat tataaagaag ttgagcgaaa aaaggatgct ttaacatata ttgaaaactg
    25801 tgaattgccc gttgttgtca agaaagatgg gttagctgct gggaaaggcg ttattattgc
    25861 agatactatt gaagcagcca gaagtgctat tgagattatg tatggtgatg aagaagaagg
    25921 tactgttgta tttgaaacgt ttttagaagg tgaagagttc tcgctaatga catttgttaa
    25981 tggtgattta gcagttcctt tcgactgtat tgcacaagat cataaacgcg catttgatca
    26041 tgatgaagga ccaaatactg gtggtatggg ggcttattgt ccagtaccac atattagtga
    26101 cgatgtttta aaacttacaa atgaaacaat tgcacaaccc attgcaaagg caatgcttaa
    26161 tgaaggttat caattcttcg gtgtattata cattggtgct attttaacta aaaatggtcc
    26221 aaaagtaata gaatttaatg cccgttttgg tgatcctgaa gctcaagtat tattaagtcg
    26281 catggaaagt gatttaatgc agcatattat tgatttagat gaaggaaaac gtactgaatt
    26341 caaatggaaa aatgaatcta ttgtaggggt catgttggca tcaaaaggat atcctgatgc
    26401 atatgaaaaa gggcataaag taagtggctt tgatttaaat gaaaactatt ttgttagtgg
    26461 attaaagaag caaggtaata cctttgttac ttcaggtggt agagttatac ttgccatcgg
    26521 aaaaggtgac aatgtacaag atgcacagcg agacgcatac gaaaaagtat cacaaataca
    26581 aagtgaccat ttattctatc gtcatgacat tgcgaataaa gcactacaac ttaaataagt
    26641 atatttaaaa aatactaaga ttagctatga agaaatctat aacgatagtt ttttcatagc
    26701 ttttttagtt gtagagtcta ggacattgat ttctgtacca aatttgtgat tattcatatg
    26761 taatacaaaa gaggcgccac aacatgtttg gatgaacaaa ataacatgtt tgtggcacct
    26821 cttttgttta gtatggaata aatggttttc tttttctata caatgaattt ctaatttagt
    26881 atctatacaa ttatggataa aatttaacct acacgaccaa gacgaacatc atctatgccc
    26941 gtgatgggta aggtgattga acaataatat gccaaagtaa taatggcaat taaaactata
    27001 ataaagatta tatctttata tgagaaaggt acgttgtaat agtaagtacg aggaccatct
    27061 ctaaatcctt tcgactccat cgcaactgat aattgatgtg cctttctaat attttggctt
    27121 aatagaggta taattaaatg cttaaatcgc tttaaccctc tataatttgc cgcgtctatc
    27181 atctgatagc gcatttttaa agatctgcga agctgtatta aagaactaat cattaaaggt
    27241 atcatacgaa tggcagccat gaatgcataa gcaacttttg atttaacctt taaatgctgc
    27301 attaaactat aaaatatcat gacaacctga gatgtaagtg cgattaagat accgaaaaat
    27361 gatatagcaa tggttcttaa tgatacatgt aaaccacgaa ctaaactttc tgttgtaata
    27421 tggataaatc cgaatttcaa aattgtatgg ctaccattcc cgtataaaat catgaatagg
    27481 gaagagagta atgcaaagcc aatacttata gttataaaaa ttgatgtaat tttaaactga
    27541 gtaccattaa acatcaataa gaaaactaac attaagatag tgatataaag cataaaatcg
    27601 aaattatgca caaatataat aaagaaaaat agtataattc caagaaatag tttcgttata
    27661 atgttgacat catcaacaaa tgattgccga actttccatt gctcatacat tcgtatcacc
    27721 atcacaatct agtaacgtac catctgaaat tttaagtctt cttgatggat aacgttcaat
    27781 tatttcatcg tcatgtgtaa ccatgacaat actttgtccc aaattaattc gtttttggaa
    27841 aagtttgatc aactggaatg tattatggct atcaagtcca aatgtcggtt catctaaaaa
    27901 gatgatatca gctttagaac ttagtgcggt agctacgcta aggcgtcgtt tttgaccaat
    27961 agacaactca taaggatgtt gatctttaac attttctaaa tctaaaagtt ttaaaagttg
    28021 tatcgtttca tcatcacttt gatctttaga aaggtgatta aaatgaatgt taatttcatc
    28081 ataaaccgaa tttgttataa attgtaattc tgggttttga taaactagat acatgtgttt
    28141 tgctgcatgt ttaatttttg ttaaacgttg attttcaaaa taaacatcac cttgatattt
    28201 aatcaattgc ataattgatt caagcaaggt agttttacca ctgccatttg cccctgtaat
    28261 tgtaatccac tcacctaaac caatttctaa atctgagaat gaaagcaacg ttgatttacc
    28321 gcgaataata cgtccatttt taaattgtaa taagtgtgag tttgttgttg gaaagtcaac
    28381 acgacttggt gcgaattccc atgcacgtgg atgccacaca ccgtattcac tgagtaaatg
    28441 aacatacttc tgtaatatga tttcaggaca ttcatcggca atgatatttc cgttataatc
    28501 catcaaaatg acgcggtcga catgattcca gatgtgttta actttatgtt caacgattac
    28561 aacagtttga tcttcccaaa gttcaattag tttagtccat aaatcttccg ttgcttgaac
    28621 atctaacatt gctgtcggtt catctaaaaa caatgttttt gattgttgaa gaatggtttc
    28681 aacaattgcc aatttctgtt tcatcccgcc acttaaatct ttgatatacg tttcaggggt
    28741 aacatttaaa ttgaccatat ttaaagcatt gataattaac gcatccatgt cttcacgtgg
    28801 tacttgtcta ttttctaaaa cgaatgcaag ttcttcgtat acttttggca tacaaaactg
    28861 gctatcaggg tcttggaaaa taacgccact taatgggtca acgattagtt catcatattt
    28921 cataggtaat tcaattaaat taggaacaat accacttaat acattcagaa gtgtactttt
    28981 accgcaacca gaaggaccga gtaaaagtac tttttctttg tcttgaatag tgatatttaa
    29041 atgatcgaaa attttacgct gaccacttgg atattttaat cgtaaatcac ttacttttaa
    29101 cactctgaat gctcctctta taagttgtcg taatcttctt tagcagctgg tctaaataat
    29161 tttgttacgc ctgtcttatc taaagctttt actaaaaggt aagataggac gccggcgact
    29221 actgcaccac taattaatct aaatacgatg aataatgtta agttccaacc tgcaacttca
    29281 tttaaatacc catagaaata atctatcggg aaagctgcga ttgctgtaca aaaacctgct
    29341 aacatagcta ccataactga acgtgattga tatttaaaaa ttgcaaagac aagttcacac
    29401 gctaaacctt gtataaaagc gtaaacgatt gtcggaatat cgaaacgacc cataatgata
    29461 gtttcgcctg cacctgcagc aaattcagcc agtaaagcaa tacctggctt tgggataatt
    29521 agatagcaga caatagctgc catgaaccaa accccgtttg ttaattgttc gaggtgaagg
    29581 cctgtagctt gcacaccatt gtaaacaaac caccataaat tgtaaataac tgcgaatact
    29641 actgaaataa gaacggttac tagtatttca gatagcttta aaccttttga catttttaca
    29701 tcctcctaat aaaaaaacgc acaaccatcc ataggaaagt tatgcgttca caatatatat
    29761 tagtaaaaca tatgtatagt aacactttcc tacgctagtt caagctagat caggttcaaa
    29821 gggtttgagg gcaagcctca tctcagtata aaacacccct agtgtgtgcg atttatttaa
    29881 ttaattatac tgtaagacgt ttgtaaactt atgtcaatag gttgtcttca tgaaatttcg
    29941 tttaattcga tttagaattt ataatattgg cattggattt aaattgaaga tgtagtagga
    30001 atgttagtaa ttaaagatat aaaaatatgt gacatgtaat aatattgagc tgataaatga
    30061 agagggatac atgtgccgag cgcaagcaaa aaagccccta acaactaaag cttgtaaggt
    30121 aggagaggga tacatgcgcc gagcacatgc aaaaaagccc ctaacaacta aaagttgtaa
    30181 ggggctctaa attaatttag tgtatcttgg atatcttgtt ttgtttgatt aatatcttct
    30241 gttttttctt cttttttatc ttttaatttt tcttcaactt ctttagcttt ttctgctgct
    30301 tttttatttt gattttcatt agacatgatt aattcctccc aaattggata attatttata
    30361 tataaatctt acccggttgt actttcgtta aacttttcta agtctatagc actatttatt
    30421 catttatcta aagacaacaa cattagatta atatataatg attttgaggt gaacataatg
    30481 tcttttctta ggaaacacgc cgaaattatt tttagctatt taatcggtat cgtttcactc
    30541 ttcactggtc tcattatttt aattaacttg ccattaatta aacaattaaa tggtggtaaa
    30601 aaagttgata cacatgttca taatgtgtgg gaatttctga atgcattttt cagtgaaatt
    30661 attaaagtaa tgagtcgatt tataggtaat ttccctatag ttagtgcaat tgtgataatt
    30721 atattcggta ttttagttat gttgattggt catacattac ttagaactat taagtatgac
    30781 tatgatattt ctatcttttt cttagttatc ggtatcatgt attttattat tactcttata
    30841 ttaatgactc aagtttatgg attctttgca gtgattttca ttattccatt tacaattcat
    30901 ataggatata tcgtctataa agatgaattg aatcaggaaa atgtaaaaaa tcatttcatg
    30961 tggataattg tgagttatgg tataagttac ttaattacac aaattgcatt gtatggcaga
    31021 attgatgcta atgaaataga gtcaattgat atcttaagtg tcaatgcttt ctttataatt
    31081 atgtggttac ttggtcaaat ggctatttgg aatttcttgt tcttgcgccg agctttacct
    31141 ttaacaaagc aagaattagg tgaagaggag ccagaattat caagaacaag taaagggaat
    31201 gtcacgaatc aaactaaaat tcacttgaaa caactccaag ataagactac agaatatgca
    31261 cgtaagacaa gaagaagtgt cgatttagat aaaattagag ctaaaagaga taaattcaaa
    31321 aagaaagtta atgatattat cgatattcaa gaagacgata ttcctgattg gatgagaaaa
    31381 ccgaaatggg ttaaaccaat gtatgtcgaa ctattttgtg gtgtcgtcat ctttttattc
    31441 acatttttag aatttaataa tcgtaatgca ttatttgtat atggtgattg gaaattatca
    31501 cagacacaat atgttattga atgggttaca ttactaattc tgttattcat tattatcgca
    31561 tatatcgcta caacgttaac tttccacttg aaaggtaagt tttattattt acaactattt
    31621 atggggagca ttttattctt taaattgtta acggaattta taaatataat gattcacgga
    31681 ctactacttt cagtgttcat tacgccaaca ttactattaa tgttattggt aatcatcatt
    31741 tcttattcgt tacaattacg agagcgacca taattaaaag cattataaaa gtactatcta
    31801 ttaaacattt tgatgtgtac gctataagtt agatatatct ctaacttact tagatacatg
    31861 tcaatgaagt ttatggatag tacttttttt gtaactagat ttgattgatt caggtgatgt
    31921 gaattaagta ttgaaaattg tatacaaagt tttagtgcaa ataaaatagt tgaaaagtta
    31981 tccatttgta aaatcaagaa aactagtaaa tagttgaagc gacttatgga atttgcgaaa
    32041 cgatatatag tatttccttt gtagaaattt aacatatatc attcgaatta ctaatttgtt
    32101 aaaatcaaca gtaagattag aagtagatga tattgaaatt tggcaaacaa tttaatctat
    32161 ataaaactac aacgaaacac agaaaggaag ttgtcagatg aaaatagcaa ctctgaacaa
    32221 aggcaaagaa acaaaatatt ttaatggata tcctttaatt gaagaagagg atatctattc
    32281 acaagatcat ttaaaagaag gagatatttt tcaaattgtg actgataaat cacaatatgt
    32341 tgcaacggct tatgttggtc gccaacataa aggattaggt tgggttctaa catacgataa
    32401 agctcaagaa atcaacacag ctttctttgt gaaattgttt aatactgcat tagcagaacg
    32461 tgattattat tttaatatag atggaacaaa tgcttttaga ttatttaatg ctgaaggtga
    32521 tggtgttggg ggattaacaa tcgacaatta cgatggtcat ttgttgattc aatggtactc
    32581 aaaaggtatt tataaattta aatatgccat tcttgaagcg gttagaaaag tatttgatta
    32641 taaatctatt tacgaaaaag taagatttaa agacagcgaa tatagtggtg gttttgttga
    32701 aggcgatgca cctgagtttc caattgttat cgaagaaaac ttcacatttt ataatgtaga
    32761 ccttgaagat ggtttgatga caggtatctt tttagatcaa aaagaagtgc gcaagaaatt
    32821 aagggatcaa tatgccaaag aacgccatgt tttaaactta tttagttata caggtgcttt
    32881 ttctgtaata gcagcaagtg aggcatcttc aacaacaagt gtagatttgg ctaatcgttc
    32941 tcgtagttta actgaagaaa attttggatt aaatgctatt gatcctaaat ctcaatatat
    33001 ttatgtcatg gacacttttg atttctataa atatgctgca cgacatggac atagttatga
    33061 cacaatcgtg atcgatccac ctagctttgc acgcaacaaa aaacgtacat tttcagtgca
    33121 aaaagattat gacaaattaa ttactggcgc cttaaatatc ttatcatctg aaggaacatt
    33181 attattatgt acaaacgcaa gtgtatatcc attaaagcaa tttaaaaata ctattaaaaa
    33241 gacgcttgaa gagagtggcg ttgattatga attaactgaa gttatggg
//
LOCUS       DAPSKH010000032        29910 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPSKH010000032 DAPSKH010000000
VERSION     DAPSKH010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 29910)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29910)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29910
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.032"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            177..4298
                     /gene="sasA"
                     /locus_tag="RPH49_001495"
     CDS             177..4298
                     /gene="sasA"
                     /locus_tag="RPH49_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000044585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-rich repeat glycoprotein adhesin SasA"
                     /protein_id="HDY5124641.1"
                     /translation="MSKRQKEFHDSLANEKTRVRLYKSGKNWVKSGIKEIEMFKIMGL
                     PFISHSIVSQDNQSISKKMTGYGLKTTAVIGGAFTVNMLHDQQAFAASDAPLTSELNT
                     QSETVGNQNSTTIEASTSTADSTSVTKNSSSVQTSNSDTVSSEKSENVTSTTNSTSNQ
                     QEKLTSTSESTSSKNTTSSSDTKSVASTSSTEQQTNISTNQSTASNTTSQSTAPASTH
                     LKQTSTTSTSTAPVKLRTFSRLAMSTFASAATTTALTANTITVNKDNLKQYMTTSGNA
                     TYDQSTGVVTLTQDAYSQKGAITLGTRIDSNKSFHFSGKVNLGNKYEGNGNGGDGIGF
                     AFSPGVLGETGLNGAAVGIGGLSNAFGFKLDTYHNTSKPNSAAKANADPSSVAGGGAF
                     GAFVTTDSTGVATTYTSSSTADNAAKLKVQPTNNTFQNFDITYNGDTKVMTVTYAGQT
                     WTRNISDWIAKSGTTNFSLSMTASTGGATNLQQVQFGTFEYTESAVTQVRYVDVTTGK
                     DIIPPKTYSGNVDQVVTIDNQQSALTAKGYNYTSVDSSYASTYNDTNKTVKMTNAGQS
                     VTYYFTDVKAPTVTVGNQTIEVGKTMNPIVLTTTDNGTGTVTNTVTGLPSGLSYDSAT
                     NSIIGTPTKIGQSTVTVVSTDQANNKSTTTFTINVVDTTAPTVTPIGDKSSEVFSPIS
                     PIKIATQDNSGNAVTNTVTGLPSGLTFDSTNNTISGTPTNIGTSTITIVSTDASGNKT
                     TTTFKYEVTRNSMSDSVSTSGSTQQSQSVSTSKADSQSASTSTSGSIVVSTSASTSKS
                     TSVSLSDSVSASKSLSTSESNSVSSSTSTSLVNSQSVSSSMSGSVSKSTSLSDSISNS
                     SSTEKSESLSTSTSDSLRTSTSLSDSVSMSTSGSLFKSQSLSTSTSDSASTSQSVSDS
                     TSNSISTSESLSESVSTSESISISNSISNSVSASTSKSESQSTSISLSTSDSKSMSTS
                     ESLSDSTSTSDSVSGSLSVAGSQSVSTSTSDSMSTSEMISDSMSTSGSLAASDSKSMS
                     VSSSMSTSQSVSTSESLSDSISTSDSDSKSLSLSTSQSGSTSTSTSTSASVRMSESQS
                     MSGSMSASQSDSTSISTSFSDSTSDSKSASTASSESVSQSVSTSTSGSVSTSTSLSTS
                     SSERTSTSLSASTSLSTSESGSTSDSTSTSDSISEAISGSGSTSVSDSTSMSESDSTS
                     VSMSQSMSGSTYNSTSVSDSESVSTSTSTSLSTSDSTSTSESLSTSMSGSQSISDSTS
                     TSMSGSTSTSESNSMHPSDSMSMHHTHSTSTSRLSSEATTSTSESQSTLSATSEVTKH
                     NGTPAQSEKRLPDTGDSIKQNGLLGGVMTLLVGLGLMKRKKKKDENDQDDSQA"
     gene            4428..5639
                     /gene="secY2"
                     /locus_tag="RPH49_001496"
     CDS             4428..5639
                     /gene="secY2"
                     /locus_tag="RPH49_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein translocase subunit
                     SecY2"
                     /protein_id="HDY5124642.1"
                     /translation="MLKLLQQYEYKIIYKRMLYTCFILFIYILGTNISIVSYNDMQVK
                     HESFFKIAISNMGGDVNTLNIFTLGLGPWLTSMIILMLISYRNMDKYMKQTSLEKHYK
                     ERILTLILSVIQSYFVIHEYVSKERVHQDNIYLTILILVTGTMLLVWLADKNSRYGIA
                     GPMPIVMVSIIKSMMHQKMEYIDASHIVIALLIILVIITLFILLFIELVEVRIPYIDL
                     MNVSATNMKSYLSWKVNPAGSITLMMSISAFVFLKSGIHFILSMFNKDVSDEMPMMTF
                     DSPIGISVYLVIQMLLGYFLSRFLINTKQKSKDFLKSGNYFSGVKPGKDTERYLNYQA
                     RRVCWFGSALVTVIIGIPLYFTLFVPHLSTEIYFSVQLIVLVYISINIAETIRTYLYF
                     DKYKPFLNQYW"
     gene            5650..7203
                     /gene="asp1"
                     /locus_tag="RPH49_001497"
     CDS             5650..7203
                     /gene="asp1"
                     /locus_tag="RPH49_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp1"
                     /protein_id="HDY5124643.1"
                     /translation="MKYFIPAWYDDQRWWQDTTVPYYQLQNKTEFDDMISLMGMHLEN
                     DLDYRLIVLNHAPNLRTFLHRYDLYETKYWSVFDEIQGFSHHAPQAINYHHLKWPDDV
                     EFVYTPYLLKCVTSEQNYTNIYFSQEGYSIWFEEFERDQLQRRYIFDDRGYLSAIRYF
                     DDHGEASYQEYLTINGDCVLYENFKNGRVTVSKRYQHHYQQTEYNNMVQLIEEKFQAM
                     IAQQIHEDDHVIVASDARHNRQIANHIPAKSLSYSFFKNRNETVSDEEYQSIVKNAHL
                     IVDSVQLERDLISHQEKYQRENTMIRITPFETRQSPNISSQLMETFIGVWIDGMSDAD
                     LQQMMQRLVDYIAQEDNYRLILLSRHQNDIPMWLRECITSVNEEYQAKQNADVNVSAL
                     MTPEDQDDIIAVKTIHAEHDVVEALRTLRLVIDMSKEPDLYLQISAISAGIPQINGQQ
                     TDYVSDYDNGRIINTVDELDDALNYYLFYLKNWNYAYAYSLKLIDAYASKNIINQLDE
                     LIEGENDAT"
     gene            7193..8761
                     /gene="asp2"
                     /locus_tag="RPH49_001498"
     CDS             7193..8761
                     /gene="asp2"
                     /locus_tag="RPH49_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp2"
                     /protein_id="HDY5124644.1"
                     /translation="MPRKFRVLQIGGDDLEPIFQHKKGVSWDYFDIGLFEFDSGYVEA
                     IEAIVEAEGRFDFIYIQAPYSETLTNLFQMISEPYNTYVDESFWSVEYEQDENVQKYV
                     VQPLHYRNIEERNNKLEAVSFSGQYGDKVSPKLALVHPNFKGDVVYQGNSELTLSGEF
                     GKEFKPIASWQNNLVYDKDKVIQIWPEFDIDGAVELQYTFRLIQTGADGALIEQIILT
                     DDMLDSPLEIPTKPFDAYISVTVKARGNGTVHLGPIHKRWSRLDMGQFLLGGSRFVDS
                     QRQEFIYYFHPGDMKPPLNVYFSGYRTAEGFEGYYMMKRMNAPFLLIGDPRVEGGSFY
                     IGSSEYEQGIINVIDETLEKLNFKSHELILSGLSMGSFGALYYGAQLNPQAIIVGKPL
                     VNIGTIAEHMRLLRPEEFGTALDVLVSNEGDTSQASIQALNQKFWQTFQKKSLSQTVF
                     AIAYMQHDDYDPHAFQELLPVLTAHQARVMNCSIPGRHNDDSPTIASWFVNFYNIILE
                     DKFGRVQHAEKQNI"
     gene            8739..9698
                     /gene="asp3"
                     /locus_tag="RPH49_001499"
     CDS             8739..9698
                     /gene="asp3"
                     /locus_tag="RPH49_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system protein Asp3"
                     /protein_id="HDY5124645.1"
                     /translation="MLKNKTFKVTWNYISQTTFMYGSKVSFSNGEVTFINPLMPSGLP
                     IHEWLMLKQFSKYKSAPSLPILRRGQHYKLHFDFDATPAGSVYFIIIFYNKNGTKLST
                     EIVKSNSITIQYPDEAYAYKIKMMNAASTSLIFRCLTITEMTHQDDLEYKSMRVTKIG
                     DDQYGNDMINVIIAEPSDTYPTISNDFLKLFGHVWLVERWMDDNIEGNIKQLKNDLQS
                     QDTLKAINLISYGSKSNVFATYVAQHLDCKVYRTSHEDDDLKEWLTEHVPGNHELKDT
                     NVEVYFKEEQDNHLNYMSRLMNPVRFLDYLDVSKLNGGEVNET"
     gene            9688..12078
                     /gene="secA2"
                     /locus_tag="RPH49_001500"
     CDS             9688..12078
                     /gene="secA2"
                     /locus_tag="RPH49_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system translocase SecA2"
                     /protein_id="HDY5124646.1"
                     /translation="MKHKLDVTINELRLKSIRKIVKRINTWSDEVKSYSDDALKQKTI
                     EFKERLASGVDTRDTLLPEAYAVAREASWRVLGMYPKEVQLIGAIVLHEGNIAEMQTG
                     EGKTLTATMPLYLNALSGKGTYLITTNDYLAKRDFEEMQPLYEWLGLTASLGFVDIVD
                     YEYQKGEKRNIYEHDIIYTTNGRLGFDYLIDNLADSAEGKFLPQLNYGIIDEVDSIIL
                     DAAQTPLVISGAPRLQSNLFHIVKEFVDTLIEDVHFKMKKTKKEIWLLNQGIEAAQSY
                     FNVEDLYSEQAMVLVRNINLALRAQYLFESNVDYFVYNGDIVLIDRITGRMLPGTKLQ
                     AGLHQAIEAKEGMEVSTDKSVMATITFQNLFKLFESFSGMTATGKLGESEFFDLYSKI
                     VVQVPTDKAIQRIDEPDKVYRSVDEKNIAMIHDIVELHETGRPVLLITRTAEAAEYFS
                     KVLFQMDIPNNLLIAQNVAKEAQMIAEAGQIGSMTVATSMAGRGTDIKLGEGVEALGG
                     LAVIIHEHMENSRVDRQLRGRSGRQGDPGSSCIYISLDDYLVKRWSDSNLAENNQLYS
                     LDAQRLSQSSLFNRKVKQIVVKAQRISEEQGVKAREMANEFEKSISIQRDLVYEERNR
                     VLEIDDAENRDFKALAKDVFEMFVNEEKVLTKSRVVEYIYQNLSFQFNKDVACVNFKD
                     KQAVVTFLLEQFEKQLALNRKNMQSAYYYNIFVQKVFLKAIDSCWLEQVDYLQQLKAS
                     VNQRQNGQRNAIFEYHRVALDSFEVMTRNIKKRMVKNICQSMITFDKEGMPVIHFP"
     gene            12096..13604
                     /gene="gtfA"
                     /locus_tag="RPH49_001501"
     CDS             12096..13604
                     /gene="gtfA"
                     /locus_tag="RPH49_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosyltransferase GtfA"
                     /protein_id="HDY5124647.1"
                     /translation="MTIYNINFGIGWASSGVEYAQAYRAKLLRRTNQDTKFVFLDFIQ
                     SENIQTLTQNIGFKDQEVIWLYQYFSDISIAPTTYTLDDVERELGHDISFRERNGKIV
                     RLYFNGKSSFVTCYLQNEQKDVVDRAEFVINSMLVRKDFYSYTRIFSEYYAPADNKAK
                     LYMRQFYNEDGSIAYNEYIDGDSSIYVFEDAVLYNKTEFIAYFLQRLNLTRDDIVILD
                     RASDIGQAVLQHKGDSKVGVVIHADHYSNNMMSEQHILWNNYYEYQFSKAKYIDFFIT
                     ATDIQNHMVCRQFEQYQGYRPRVYTIPVGSIDALSYPTLSRKPYAMISASRLANEKHI
                     DWLVKAVIVAKRQVPELTFDIYGEGSEKTRLRKIIDTHRAQDYIRLLGHVKLDEIYND
                     YELFLSASTSEGFGLTLMEAVGSGLGMIGLNVNYGNPTFIRDGENGYLVPFDTDEDSV
                     DDVVAKLAHAIVMYFNNGPQTPHDISYEVAQQFMTQDIILKWETLVQEVLHD"
     gene            13597..14955
                     /gene="gtfB"
                     /locus_tag="RPH49_001502"
     CDS             13597..14955
                     /gene="gtfB"
                     /locus_tag="RPH49_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory Sec system glycosylation chaperone
                     GtfB"
                     /protein_id="HDY5124648.1"
                     /translation="MIKLFDYFNDHSRKLYESFKASKLEEDLTIVLNDNGFLPDDVIS
                     PYQFFADNHNTENMKPRFFNQVTVPAFWEIKGNNNSATINDMGRLRGKIFYQSGERPR
                     IVSRVEWFDDQQRVRFVDYYSKNGIKFAQTVYDLNRKAILKKYMTAEGKEVIYENFVT
                     SDVILDWQGKSYFFPSKLAFVLFFIKQLEITEHHFVINSLALPFSVLYNLPSNGSDVL
                     VWQEQCDGNVPGNMQLMCKGDMKRHCNIIIPDKNEYETMLNIADAKVQSRILQGGYLY
                     NYRSRNRYTKEIVILTNSDQLRNIKVLVETLPDFKFHIAAITEMSDKLMQLDQYANVH
                     LYPSINIDRVNELYQLCDIYLDINEGNEILNAVEQAFDYELLILGYRQTAHHAKVTLS
                     EHLFEHNDEITMESKDQLIQMLESLKDQQQFRDALLAQKAHAHEISREQFEQVFKQAL
                     ES"
     gene            15197..17104
                     /gene="sasF"
                     /locus_tag="RPH49_001503"
     CDS             15197..17104
                     /gene="sasF"
                     /locus_tag="RPH49_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-wall-anchored protein SasF"
                     /protein_id="HDY5124649.1"
                     /translation="MAKYRGKPFQLYVKLSCSTMMATSIILTNILPYDAQAASEKDTE
                     ISKEILSKQDLLDKVDKANRQIEQLKQLSASSKAHYKAQLNEAKTASQIDEIIKRANE
                     LDSKDNKGSQIEMNGQSDIDSKLDQLLKDLNKVSSKVDRGQQSGKDDLNAMKNDMSQT
                     ATTKYGEKDNENDEAMVDKALEDLDHLNQQIHKSKDASKDTSEDPAVSTTDNNHEVAK
                     TPNNDGSGHVVLNKFLSNEENQSHSNRLTDKLQGSDKINHAMIEKLAKSNASTQHYTY
                     HKLNTLQSLDQRIANTQLPKNQKSDLMSEVNKTKERIKSQRNIILEELARTDDKKYAT
                     QSILESIFNKDEADKILKDIRVDGKTDQQIADQITRHIDQLSLTTSDDLLTSLIDQSQ
                     DKSLLISQILQTKLGKAEADKLAKDWTNKGLSNRQIVNQLKKHFASTGDTSSDDILKA
                     ILNNAKDKKQAIETILATRIERQKAKLLADLITKIETDQNKIFNLVKSALNGKADDLL
                     NLQKRLNQTKKDIDYVLSPIVNRPSLLDRLNKNGKTTDLNKLANLMNQGSNLLDSIPD
                     IPTPKPEKTLTLGKGNGLLSGLLNADGNVSLPKAGETIKEHWLPISVIVGAMGVLMIW
                     LSRRNKLKNKA"
     gene            17271..17831
                     /locus_tag="RPH49_001504"
     CDS             17271..17831
                     /locus_tag="RPH49_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDY5124650.1"
                     /translation="MSRKTALLVLDMQEGIASSVPRIKNIIKANQRAIEAARQHRIPV
                     IFIRLVLDKHFNDVSSSNKVFSTIKAQGYAITEADASTRILEDLAPLEDEPIISKRRF
                     SAFTGSYLEVYLRANDINHLVLTGVSTSGAVLSTALESVDKDYYITVLEDAVGDRSDD
                     KHDFIIEQILSRSCDIESVESWKSSL"
     gene            complement(18098..19957)
                     /locus_tag="RPH49_001505"
     CDS             complement(18098..19957)
                     /locus_tag="RPH49_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase domain-containing protein"
                     /protein_id="HDY5124651.1"
                     /translation="MPKNKILIYLLSTTLVLPTLVSPTAYADTPQKDTTAKTTSHDSK
                     KSNDDETSKDTTSKDTDKADNNNTSSQDNNDKKFKTIDDSTSGSNNIIDFIYKNLPQT
                     NINQLLTKNKYDDNYSLTTLIQNLFNLNSDISDYEQPRNGEKSTNDSNKNSDNSIKND
                     TDTQSSKQDKADNQKAPKSNNTKPSTSNKQPNSPKPTQPNQSNSQPASDDRANQKSSS
                     KDNQSMSDSALDSILDQYSEDAKKTQKDYASQSKKDKNEKSNTKNPQLPTQDELKHKS
                     KPAQSFNNDINQKDTRATSLFETDPSISNNDDSGQFNVVDSKDTRQFVKSIAKDAHRI
                     GQDNDIYASVMIAQAILESDSGRSALAKSPNHNLFGIKGAFEGNSVPFNTLEADGNQL
                     YSINAGFRKYPSTKESLKDYSDLIKNGIDGNRTIYKPTWKSEADSYKDATSHLSKTYA
                     TDPNYAKKLNSIIKHYQLTQFDDERMPDLDKYERSIKDYDDSSDEFKPFREVSDSMPY
                     PHGQCTWYVYNRMKQFGTSISGDLGDAHNWNNRAQYRDYQVSHTPKRHAAVVFEAGQF
                     GADQHYGHVAFVEKVNSDGSIVISESNVKGLGIISHRTINAAAAEELSYITGK"
     gene            20168..23149
                     /locus_tag="RPH49_001506"
     CDS             20168..23149
                     /locus_tag="RPH49_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDY5124652.1"
                     /translation="MKNAFKLFKMDLKKVAKTPAVWIILAGLAILPSFYAWFNLWAMW
                     DPYGNTGHIKVAVVNEDKGDTIRGKKVNVGNTMVNTLKKNKSFDWQFVSREKADHEIK
                     MGKYFAGIYIPSKFTHEITGTLRKQPQKADVEFKVNQKINAVASKLTDTGSSVVVEKA
                     NEQFNKTVTRALLEEANKAGLTIEENVPTINKIKNAVYSADKALPKINDFANKIVYLN
                     NHQADLDKYANDFRKLGNYKGDILDAQKKLNEVNGAIPQLNEKAKLILALNNYMPKIE
                     KALNFAADDVPAQFPKINQGLNIASQGIDQANGQLNDAKDFVTQVRSRVGDYQDAIRR
                     AQDLNRRNQQQIPQNSAANNETSNSAPAAGNGVASTPPSVPSGDTAPNNNVTQNTAPN
                     GNNAPVSTTPQSTSGKKDGQSFADITTTQVSTANENTQNITDKDVKSMEAALTGSLLS
                     LSNNLDTQAKAAQKDSQALRNISYGILASDKPSDFRESLDNVKSGLEYTTQYNQQFID
                     TLKEIEKNENVDLSKEIDKVKAANNRINESLRLVNQLSNALKNGSSGTAEATKLLDQL
                     SKLDSSLSSFRDYVKKDLNSSLVSVSQRIMDELNKGQTALSNVQSKLNTIDQVINSGQ
                     AILKNGKTRIDRLQTVLPSIEQQYISAVKNAQANFPKVKSDVAKAANFVRNDLPQLEQ
                     RLTNATASVNKNLPTLLNGYDQAVGLLNKNQPQAKKALSDLADFSQNKLPDVEKDLKK
                     ANKIFKKLDKDDAVDKLIDTLKNDLKKQAGIIANPINKKTVDVFPVKDYGSGMTPFYT
                     ALSVWVGALLMVSLLTVDNKHKSLEPVLTTRQVFLGKAGFFIMLGMLQALIVSVGDLL
                     ILKAGVESPVLFVLITIFCSIIFNSIVYTCVSLLGNPGKAIAIVLLVLQIAGGGGTFP
                     IQTTPQFFQNISPYLPFTYAIDSLRETVGGIVPEILITKLIILTLFGIGFFVVGLILK
                     PVTDPLMKRVSEKVDQSNVTE"
     gene            complement(23261..24199)
                     /gene="manA"
                     /locus_tag="RPH49_001507"
     CDS             complement(23261..24199)
                     /gene="manA"
                     /locus_tag="RPH49_001507"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDY5124653.1"
                     /translation="MALFLQPVFKDRIWGGHALKAFNYDIPNETTGECWAISAHPNGP
                     NTIINGPYKDMTLDQLWSQHRELFDNDSRDSFPLLTKVLDANDKLSVQVHPDDDYALK
                     HEGELGKTECWYILDAAPGAEIIYGVHAHNKQTLIDMIDNHEFDSLFKRIPVKPGDFY
                     YVPAGTVHAIGSGILILETQQSSDTTYRIYDYDRRDQNGQLRDLHLEQSKDVIELGNH
                     EPNTTPITTHIDTHTVTQFVDNQYFAVYKWDIHGDLKFNKPHAYCLVTIIDGTGTLTV
                     NDKHYDIPKGSSFILTTEDEDIHFVGNISAIVSHPG"
     gene            complement(24213..26165)
                     /locus_tag="RPH49_001508"
     CDS             complement(24213..26165)
                     /locus_tag="RPH49_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIABC"
                     /protein_id="HDY5124654.1"
                     /translation="MKIVAITSCPNGIAHTYMAQEKLEQVAKEMGVDIKVETQGGVGA
                     ENVLTTQDIEEADGVIIAADKQVDLSRFVGKRLINENVREGIHNPRGLIQRIINQDAP
                     IYQSETNYHSKDRGKSKSGIQMVYQHLMNGVSFMVPFIVVGGLLIAIALTLGGETTSK
                     GLVIPDDSFWKSIENIGSLAFKFMVPILAGYIAVSIADKPGLVPGMIGGAIAADGSFY
                     GSDAGAGFLGGIVAGFLAGYIAKWIKDIKVPKAMAPIMPIIIIPIISSVVVGLIFIFL
                     IGAPISNIFEALTTWLKSMQGANIIILAMIIGAMIAFDMGGPVNKVAFLFGSALIAEG
                     NYAVMGMVAVAVCTPPIGLGLATFVQKYKFNHSEREMGKASFTMGLFGITEGAIPFAA
                     QDPLRIIPANIIGAMIASVIAAIGGVGDRVAHGGPIVAVLGGIDHVLLFIFAVIVGSL
                     VTMTTVLLLKRNTPVIAVDAPAQHTQLHDTDITQHDTEVDNVDNTAKHSHHNKPSHVF
                     DQQTMIITDHDMSRNEAIDMLIHKLKICRYVEHTSHLKNAILEREMESTTAIGMNVAI
                     PHAKSDVVKQPIVAVMKNNHGVKWESLDGSLPQLIFLIAVPNNSQDTHLKILQRLSKA
                     LMNDETRQSLINANSTTEIYNLLMKI"
     gene            complement(26242..28116)
                     /locus_tag="RPH49_001509"
     CDS             complement(26242..28116)
                     /locus_tag="RPH49_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDY5124655.1"
                     /translation="MLDRHLKLLQFFIKNPSKHISSNEIAEHVNVSNRTVRNDIHVIN
                     SNFMDDIIVSIKSKGYQLNTSQYTLETITERYTHIQSYKEKLLLSMAYQLLMHNKSQT
                     LQQLEQDYLLSKTVLNDYFIRIQQWCQKFNIALTIKKKQGIVVDGTDNDITNAIIHLN
                     QLSSGHVHVEDLILNELPDSHQRMISHIIQETLQQHSIETTDIQIQQLLIHLILIIKR
                     KQSLSELDTLNHDAKLISQSCIKQINERLGYDLNEQVINMFSFFIAYHFNKLDIGIER
                     IFIQSYIDRLIELMQQRIHVPFNEDSILQQNLYNHFSKAYLRITQNIYLNNPLVIEIK
                     KLYPFVFNTLFEAIDKLAVDTDIEMSEDEIAFLTIHFQAAIERRTKTQLNVVIACYYG
                     LGVSNFLETKINNLSEELLVINTIKLENITHYHFDNVDLLITTHDIPKQTLNILPKHL
                     STIKVAPLFSEDDRHKIRHIVKQKQNPVQAHHHMDTVNFLVVNTEQKPRHTVQIFEEA
                     QKILQAHHAIVEGYIESALEREKSSSTYIGNFMAIPHGDPEKVLQSHVLIFRTKDVFP
                     WRQHDVKLVFFLAISQKDTAFTKQMMQLIANLDDDSVNHLCNLDDHSLKQQLFEYLQE
                     "
     gene            complement(28356..28829)
                     /locus_tag="RPH49_001510"
     CDS             complement(28356..28829)
                     /locus_tag="RPH49_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124656.1"
                     /translation="MKKFLITVVIILLIGALGFAIYAAINHSTSSNHNNEQDNKATHQ
                     KKDTEVNHQKDENTNNTNENQNNNGVTNGNQSSTPSTVQNNGSTAPANTQPSNPNQSN
                     SNQSNPNQSNSNHGGSSQPSTNNQNHKQQNTPPANKSNNTNTPSKQTPQVQSPKN"
     gene            29084..29611
                     /gene="isaB"
                     /locus_tag="RPH49_001511"
     CDS             29084..29611
                     /gene="isaB"
                     /locus_tag="RPH49_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunodominant staphylococcal antigen IsaB"
                     /protein_id="HDY5124657.1"
                     /translation="MNQTTKLCAATTLALGTLIGATVVGTASPIHQETQAATTPYYTY
                     HGYIGHNANFIMDKHFINAIKYDNVTFNGIKLAKTNATKKVEKYDQTFKGVTAKGNEA
                     NQLQFIVKNNISLKDIQKAYGKDLKKENNKTKESDSGIFYYQHSKKSLGIWFVVDHNR
                     VVEVTVGHTPYKTSK"
BASE COUNT        10391 a         4576 c         5568 g         9375 t
ORIGIN      
        1 aaaattatac taaatcccac acaataaaga aggcgatttc atcaaagaat atacttttgg
       61 aaaaattgga ttttgacaaa ttaagtattt tttatttgaa aaaagagttg tattaaattg
      121 aatagtggca tatattataa tctaatgaat gtaaagataa tacaaggagt tattacatga
      181 gcaaaagaca gaaagaattt catgacagct tagcaaacga aaaaacaaga gtaagacttt
      241 ataaatctgg aaaaaattgg gtaaaatccg gtattaaaga aatagaaatg ttcaaaataa
      301 tgggactacc atttattagt catagtatag tgagtcaaga taatcaaagc attagtaaaa
      361 aaatgactgg atacggactg aaaacgacgg cggttattgg tggtgcattc acggtaaaca
      421 tgttgcatga ccagcaagct tttgcggctt ctgatgcacc attaacatct gaattaaata
      481 cacaaagtga aacagtaggt aatcaaaact caacgacaat cgaagcatca acatcaacag
      541 ccgattccac aagcgtaacg aaaaatagta gttcggtaca aacatcaaat agtgacacag
      601 tctcaagtga aaagtctgaa aatgtcactt cgacaactaa tagtacaagt aatcaacaag
      661 aaaaattaac atctacatca gaatcaacat cctcaaagaa tactacatca agttctgata
      721 ctaaatctgt agcttcaact tcaagtacag aacaacaaac taatatatca acaaatcaaa
      781 gcactgcatc aaatactact tcacaaagca cagcgccagc ttcaacccat ttaaaacaaa
      841 ctagcacaac gtcaaccagc acagcacctg tcaaacttcg aactttcagt cgattagcta
      901 tgtcaacctt tgcatcagct gcgacgacaa ccgcattaac tgctaataca attacagtta
      961 ataaagataa cttaaaacaa tatatgacaa cttcaggtaa tgccacttat gaccaaagta
     1021 caggggtcgt aacgttaacg caggatgcat atagccaaaa aggtgctatt acattaggaa
     1081 cacgtattga ctctaataag agttttcatt tttctggaaa agtaaattta ggtaataaat
     1141 acgaaggtaa tggaaatggt ggagatggta tcggctttgc cttttcgcca ggtgtattag
     1201 gtgaaacagg gttaaacggt gccgcagtag gtattggtgg cctaagtaac gcatttggct
     1261 tcaaattgga tacgtatcac aatacatcta aaccaaattc agctgcaaag gcgaatgctg
     1321 acccatctag tgttgctggt ggaggtgcgt ttggtgcctt tgttacaaca gatagtactg
     1381 gcgttgcgac aacgtacaca tcaagttcaa cagctgataa tgctgcaaag ttaaaagttc
     1441 aacctacaaa caacacgttc caaaattttg atattactta taatggtgat acaaaggtta
     1501 tgactgtcac gtatgcaggt caaacatgga cacgtaatat ttcagattgg attgcaaaaa
     1561 gtggtacgac caacttttca ttatcaatga cagcctcaac aggtggcgcg acaaatttac
     1621 aacaagtaca atttggaaca tttgaatata cagagtctgc tgttacacaa gtgagatacg
     1681 ttgatgtaac aacaggtaaa gatattattc caccaaaaac atattcagga aatgttgatc
     1741 aagtcgtgac aatcgataat caacaatctg cattgactgc taaaggatat aattacacat
     1801 ctgtcgatag ttcatatgca tcaacttata atgatacaaa taaaactgta aaaatgacga
     1861 atgctggaca atcagtgaca tattacttta ctgatgtaaa agcaccaact gtaactgtag
     1921 gcaatcaaac cattgaagtg ggtaaaacaa tgaatcctat tgtgttgact acaacggata
     1981 atggtacagg gactgtgaca aatacagtta caggattacc aagcggatta agttatgata
     2041 gtgcaacgaa ttcaatcatt gggacaccaa caaaaattgg tcaatcaaca gtgacagtag
     2101 tatctactga ccaagcaaat aacaaatcga cgacaacttt tacaataaat gttgtggata
     2161 cgacagcacc aacagtgacg ccaataggag ataaatcatc agaagttttt tctccaatat
     2221 caccgattaa aattgctacg caggacaata gtggtaatgc agtaacaaat acagtcacag
     2281 gattgccgtc tggactaaca ttcgatagta caaataatac cattagtggt acaccaacaa
     2341 acattggtac aagtactata acaatcgttt ctacagatgc gagcggtaac aaaacgacga
     2401 caacttttaa atatgaagta acaagaaata gtatgagtga ttccgtatca acatcgggaa
     2461 gtacccaaca atcacaaagt gtgtcaacaa gtaaagctga ctcacaaagt gcatcaacga
     2521 gtacatcagg atcgattgtg gtatctacat cagctagtac ctcgaaatcg acaagtgtaa
     2581 gcctatctga ttctgtgagt gcatctaagt cattaagcac atctgaaagt aatagtgtat
     2641 caagctcaac aagcacaagt ttagtgaatt cacaaagtgt atcatcaagc atgtcaggtt
     2701 cagttagtaa atcaacatca ttaagcgatt ctatttcgaa ctctagcagt actgaaaaat
     2761 ccgaaagtct atcaacaagt acatctgatt cattgcgtac atcaacatct ttaagtgatt
     2821 cagtaagcat gagtacatca ggaagcttgt ttaagtcaca aagcttatca acaagtacat
     2881 ccgattcggc tagtacttca caatcggtaa gtgatagtac atcaaattca attagtacgt
     2941 cagaatcatt gagtgagtca gttagtacat cagaatctat aagtatttct aatagcattt
     3001 cgaattcagt gagtgcatca acaagcaaat cggaatcaca aagtacatca atatcattaa
     3061 gtacaagcga ttctaaatcg atgagtacat cagaatcatt aagcgattca acgagcacaa
     3121 gtgattcggt atctggatca ttaagtgtag cagggtcaca aagtgtctca acaagcacat
     3181 cagactcaat gagcacgtct gaaatgataa gcgattctat gagtacaagt ggatcattag
     3241 ctgcatcaga cagtaaatca atgtctgtaa gtagttcgat gagcacttct cagtcagtta
     3301 gtacatcaga atcattaagt gattcgataa gtacatcgga ttctgacagt aagtcattat
     3361 cattaagtac tagtcaatca ggttcaacaa gtacatcaac gtcgacaagt gcttcagtac
     3421 gtatgtcgga atcacaaagt atgtctggtt caatgagtgc aagtcaatcc gattcaacga
     3481 gcatatcaac gtcgtttagt gattcaacaa gtgatagcaa atcagcatca acggcctcaa
     3541 gtgaatcagt atcacaaagt gtctcaacaa gtacatctgg ttcggtgagt acttcgacat
     3601 cgctaagtac tagtagttca gaacgcacat caacatcatt gagtgcttcg acaagtttaa
     3661 gcacatcaga gtctggttca acgagcgact caacgtcgac gagcgattct atcagtgaag
     3721 cgatatctgg ttcaggttca acgagcgtat ctgactcaac atcaatgagt gaatccgatt
     3781 caacaagtgt ttcaatgtca caaagtatgt ccggttcaac gtacaactcg acttcagtga
     3841 gcgactcaga atcagtgtca acaagcacat caacgtcatt gagcacatcc gattcgacaa
     3901 gcacatccga atcgctgagt acatctatgt ctggttcaca aagcatttct gactcaacat
     3961 caacaagtat gtccggctca acaagtacat ctgaatctaa ctcaatgcat ccgtcagact
     4021 caatgagtat gcatcatact cacagcacga gcacatctcg cttatcaagt gaagcaacaa
     4081 cgagcacgag tgaatctcag tctacattaa gtgcaacatc tgaagtgact aaacataatg
     4141 gcacgcctgc acaaagtgaa aaaagattgc cagatacagg tgactcaata aaacaaaatg
     4201 gattactagg tggcgttatg acattattag ttggtttagg tttaatgaag agaaagaaaa
     4261 agaaagatga aaatgatcaa gatgattctc aagcataaat tgaatttata gctggctaaa
     4321 attaaaaaga ctgaggcacc aatcactaga aaaatcgata taggatttta ataattagtg
     4381 atgaaccctt agtcttttta atgtttttga tataaaagag gtgcaacatg ttaaaacttt
     4441 tacaacaata cgaatataaa attatatata aacgtatgct atacacatgt tttatattat
     4501 ttatttatat attaggtaca aacatttcca tcgtttccta taacgatatg caagtaaaac
     4561 atgagtcatt ttttaaaata gctatttcta atatgggtgg agacgttaat actttaaaca
     4621 ttttcacttt aggattaggt ccgtggttaa catcaatgat tatcttgatg cttatttctt
     4681 atcggaatat ggataaatac atgaaacaaa caagtcttga gaagcattat aaagagcgca
     4741 tcttaacatt aattttaagt gttattcaaa gttattttgt gattcatgaa tatgtttcga
     4801 aagaacgtgt tcatcaagac aatatttact taacaatatt gattttggtt actggaacga
     4861 tgttattagt ttggttagct gacaaaaata gtcgttacgg catcgcagga ccaatgccga
     4921 ttgtaatggt tagtattatt aaatcaatga tgcatcaaaa aatggaatat atagatgcaa
     4981 gtcatattgt gattgcgttg ttaatcatcc ttgtgataat cacattgttt atcttattat
     5041 ttattgaatt agtagaagtg agaataccat atatcgattt aatgaacgtt tccgcaacaa
     5101 atatgaaatc ttatttatct tggaaagtta accctgcagg cagtattact ttaatgatga
     5161 gcatttcagc ttttgttttc ttaaaaagtg gcattcattt tattttatct atgtttaata
     5221 aagacgtttc agatgaaatg ccaatgatga cattcgatag tccaattggt atttcagtat
     5281 atttagtgat tcaaatgtta ttgggttatt ttttatcgag atttttaata aatacaaaac
     5341 aaaaatcaaa agacttctta aagagtggca attatttttc aggagttaaa cctggtaagg
     5401 atacagaacg ttatttaaat tatcaagcac gacgcgtatg ttggtttgga tcggcattag
     5461 ttacagtcat tattggtata ccactttatt tcacattgtt tgtaccgcat ttatctactg
     5521 aaatttattt ctcagtacaa ctgattgtat tagtttatat cagtattaat attgcagaaa
     5581 caattcgtac atatttatat tttgataaat ataagccatt tttaaaccag tattggtaag
     5641 gaggtaatta tgaaatactt tattccagct tggtacgatg accaacgatg gtggcaagac
     5701 acgactgtgc cgtattatca actacaaaat aagacggaat ttgacgatat gattagttta
     5761 atgggaatgc accttgaaaa tgacttagat tatcgtctga ttgttctcaa tcatgcacca
     5821 aatttaagaa catttttaca tcgatatgac ttatatgaga caaagtattg gtctgtgttt
     5881 gatgaaattc aaggattcag tcaccatgcg ccacaagcga ttaattatca ccacttaaaa
     5941 tggccggatg acgtagaatt cgtgtacacg ccgtatttat taaaatgtgt gacgagtgaa
     6001 cagaactata caaatattta ttttagtcaa gaagggtatt caatttggtt tgaagaattt
     6061 gaaagagatc agttacaacg gcgttatatt tttgatgaca gaggttattt atcagcgata
     6121 cgttattttg atgatcatgg agaggcttct taccaagaat atttaacgat taatggagat
     6181 tgtgtgcttt acgaaaactt taaaaatgga cgagtcactg tttcaaaaag atatcaacat
     6241 cattatcaac aaacagaata taacaatatg gttcaactaa ttgaagaaaa atttcaagca
     6301 atgattgcac aacaaataca tgaagatgat catgtgattg tggcttcaga tgctaggcac
     6361 aatcgacaaa tagccaatca tattccagcg aaatcattaa gttattcatt ttttaaaaat
     6421 agaaatgaaa ctgtgtcaga tgaggaatat caatctatcg taaagaatgc ccatttaatt
     6481 gttgatagtg tgcaactaga acgtgattta attagtcatc aagagaagta tcagcgagag
     6541 aatacaatga ttcgaatcac accatttgaa acgagacaat cacctaatat aagtagtcaa
     6601 ttgatggaaa catttatagg tgtatggata gatggtatga gtgacgctga tttgcaacaa
     6661 atgatgcaac gacttgtgga ttatatcgca caagaagata attaccgttt aattttatta
     6721 tcacgtcatc aaaatgacat accaatgtgg cttcgtgaat gtattacgtc ggtaaatgag
     6781 gaataccaag ctaaacagaa tgcggatgtt aatgtttcag cattaatgac acctgaagat
     6841 caagatgaca ttattgctgt taagacgata catgctgaac atgatgttgt agaagcattg
     6901 cggacgttgc gacttgtgat agatatgtca aaagaacctg acttgtattt acaaattagt
     6961 gcaattagcg ctgggattcc acaaattaat ggtcaacaaa cagattacgt ctctgattat
     7021 gacaatggcc gtattataaa tacagttgat gaattagatg atgcgttaaa ttattattta
     7081 ttttatttga aaaattggaa ttatgcgtac gcctattctt taaaattaat agatgcatat
     7141 gcttctaaga atattattaa tcagctcgat gagttaatag aaggtgaaaa tgatgccacg
     7201 taaatttaga gttttgcaaa ttggaggaga cgatttagaa cctattttcc aacacaaaaa
     7261 aggtgtgagt tgggattact tcgatattgg attgtttgaa tttgatagtg gttatgtaga
     7321 ggctattgaa gcgattgttg aagcagaagg gcgctttgat tttatctata ttcaagcacc
     7381 atactcggag acattaacga atttattcca aatgataagc gaaccataca atacgtatgt
     7441 tgatgaatca ttttggtctg ttgaatatga acaagacgaa aatgtccaaa aatacgttgt
     7501 tcaaccatta cattaccgga acattgaaga acgtaataat aaattagagg cagttagctt
     7561 ctcaggacag tatggagata aggtttctcc taagttagca cttgttcatc cgaattttaa
     7621 aggagatgtc gtttaccaag gtaattcaga gctcacgttg agtggagaat ttggaaaaga
     7681 atttaaacct atcgcatctt ggcaaaataa tctcgtttac gataaagata aagtcattca
     7741 aatatggcca gaatttgata ttgatggtgc ggtcgagttg caatatacat ttagattgat
     7801 tcagactggc gctgatggtg cattaattga gcaaatcata ttaactgatg atatgttaga
     7861 cagtccttta gagataccta cgaaaccatt tgatgcatat ataagtgtaa ctgttaaggc
     7921 gcgtggcaac gggacggtac atttaggacc tatacacaaa cgatggtcta gattagacat
     7981 gggtcaattt ttacttggtg gtagtcgttt cgtagatagt caacgacagg aatttattta
     8041 ttatttccac cctggtgata tgaaaccacc actaaacgta tattttagtg gttatcgaac
     8101 agcggaaggt ttcgaaggat attatatgat gaaacgtatg aatgcaccgt ttttacttat
     8161 cggcgatcct cgtgttgaag gtggtagctt ttatatcggt tcatctgaat atgaacaagg
     8221 tattatcaat gttattgacg agacattaga aaagctgaat tttaaatcac atgaattaat
     8281 attatctggt ttatctatgg gttcatttgg tgccttgtat tatggtgctc agttaaatcc
     8341 tcaggcaatt attgttggta aaccacttgt taatattgga acgattgctg aacatatgcg
     8401 attacttaga ccagaagagt tcggtacagc attagacgtc ctggtgtcta atgaaggtga
     8461 tacatctcaa gcgtcgatac aggcattaaa tcaaaaattt tggcaaacat ttcaaaagaa
     8521 atcattgtca caaactgttt ttgccatagc atatatgcaa catgatgatt atgatccaca
     8581 tgcatttcaa gagctattac ctgtattgac agcacaccaa gcaagagtga tgaattgcag
     8641 tattcctggg cgacataatg atgattcacc taccattgca agttggtttg ttaattttta
     8701 caacattatt ttggaagaca agtttgggag agttcaacat gctgaaaaac aaaacattta
     8761 aagttacttg gaattatatt tcacaaacta catttatgta tggctctaaa gtatcatttt
     8821 caaatggtga agtgactttt ataaaccctt tgatgccctc tggattaccg attcatgagt
     8881 ggttgatgtt aaagcaattt tcaaaatata aaagtgcgcc aagtttacca attttgcgta
     8941 gaggacagca ttataaattg cattttgatt ttgatgcaac gcctgctggt tcagtgtatt
     9001 ttatcatcat tttttataat aaaaatggca caaaactaag tactgagatt gtaaagtcaa
     9061 atagtatcac gattcaatat cctgatgaag cctatgctta taaaataaaa atgatgaatg
     9121 cagcatcgac gagtcttata tttagatgtt taacaatcac agagatgacg catcaagatg
     9181 atttagaata taaaagcatg cgggtgacga agataggcga tgaccaatat ggaaatgata
     9241 tgatcaatgt cattattgca gaaccatctg acacctatcc aactatttcg aatgattttt
     9301 tgaaactgtt tggtcatgtt tggctcgttg aacgttggat ggacgacaat atcgagggaa
     9361 atattaagca actaaagaat gatttgcaaa gtcaagatac cctaaaggct attaatttga
     9421 ttagttatgg gtcaaagtca aatgtttttg caacttatgt cgctcagcat ttggattgca
     9481 aagtgtatcg tacaagccat gaagatgatg atttaaaaga atggcttaca gaacatgtcc
     9541 caggaaatca tgaactaaaa gatacaaatg tcgaggttta ttttaaagaa gagcaagaca
     9601 accatctaaa ctatatgtca cgtttaatga atccagtacg atttttagat tacttagatg
     9661 tatcgaaact gaatggtggg gaagtaaatg aaacataaac tagatgttac gataaacgaa
     9721 ttaagactaa agtcgattag aaaaatagtg aaacgcatca atacatggag cgatgaagtt
     9781 aaatcatatt ctgatgatgc gttaaaacaa aagacaatag aatttaaaga acgtttagca
     9841 tcaggagttg atacacgaga tacattgttg cctgaagctt atgcagtggc acgtgaagcg
     9901 agctggagag tattaggtat gtatcctaaa gaagttcagt taatcggagc gattgtattg
     9961 catgaaggta acattgcgga gatgcaaaca ggcgaaggta aaacattaac agcaacgatg
    10021 cctttatatt taaatgcact ttcgggaaaa ggaacatatt taattacaac gaatgattat
    10081 ttagcgaagc gtgattttga agagatgcaa ccattatatg aatggttagg tttaactgct
    10141 tcattaggtt ttgttgatat tgtggattat gagtatcaaa aaggggaaaa acgtaatata
    10201 tatgaacatg atattatata tacaactaat ggacgtctcg gttttgatta tttaattgat
    10261 aatttggctg atagtgcgga aggaaaattt ttaccacaat taaattacgg tattattgat
    10321 gaagtggatt caatcatttt agatgctgcg caaacaccat tagttatttc gggtgcacca
    10381 agattacaat caaatctatt tcatattgtg aaagagtttg tagatacatt gattgaagac
    10441 gtgcatttta aaatgaagaa gaccaaaaag gaaatatggc tgttaaatca aggtattgaa
    10501 gcggcacaat catactttaa tgttgaagat ttatatagcg aacaagcgat ggtcctagtg
    10561 cgtaatatta atctagcact gcgcgcgcaa tatttgtttg aatctaatgt cgattacttc
    10621 gtatataatg gtgatattgt tttaattgac cgtattacag gtcgtatgtt accggggact
    10681 aagttgcaag ctggacttca ccaagctatt gaagcgaaag aaggtatgga ggtttcaaca
    10741 gataaaagtg ttatggcaac aattaccttc cagaatttat ttaaactttt tgaatcattt
    10801 tcaggtatga cagctacagg aaaattaggc gaatcagagt tctttgattt gtattcaaaa
    10861 atagtcgtac aagtaccaac tgataaagcg attcaacgta tcgatgaacc agataaagtg
    10921 tatcgttcag ttgatgagaa aaacatcgcg atgattcatg atattgttga acttcatgaa
    10981 acggggagac cggttttact cataacgaga actgctgaag cggctgaata cttttcgaaa
    11041 gtattattcc aaatggatat tcctaataat ttactcattg cgcaaaatgt tgcaaaagaa
    11101 gcgcagatga tagctgaagc agggcaaatt ggttccatga ctgttgcgac tagtatggca
    11161 ggtcgaggca cagatattaa acttggtgaa ggtgtcgaag cattaggtgg attagctgtt
    11221 attattcatg aacatatgga aaatagccgt gtagacaggc aattacgtgg tcgttctggt
    11281 agacaagggg atccgggatc atcttgtata tatatttcac tagatgatta tttagttaag
    11341 cgatggagcg atagtaattt agcggaaaat aatcaattat attcattaga tgcacaacga
    11401 ttatcgcaaa gtagtttgtt taatcgcaaa gttaagcaaa ttgtagttaa agcgcagcgt
    11461 atctcggaag aacaaggggt taaagctcgt gaaatggcta atgaatttga aaaaagcatt
    11521 agtatacagc gagatcttgt atacgaggaa cgtaatcgag ttttagaaat agatgatgct
    11581 gagaatcgag attttaaagc gttagctaaa gatgtgtttg aaatgtttgt aaatgaggaa
    11641 aaggtgctaa caaaatcgcg tgttgtcgag tatatttatc aaaatttaag tttccaattt
    11701 aataaagatg tggcttgtgt taattttaaa gataagcaag cagtagtgac atttttatta
    11761 gagcaatttg aaaagcaatt agctttgaat cgtaaaaaca tgcaaagtgc atattattat
    11821 aatattttcg ttcaaaaagt ctttttgaaa gcaattgatt catgttggtt agaacaagtc
    11881 gactatttac aacaattaaa agcaagcgtt aatcaacgac aaaatgggca acgtaacgct
    11941 atttttgaat accatagagt tgccttagat tcatttgaag ttatgacacg aaatatcaaa
    12001 aaaagaatgg tgaaaaatat ttgtcaaagc atgattacat ttgataaaga gggtatgcca
    12061 gttatacatt ttccataaat gaaaaggggt agcgcatgac aatatataat ataaactttg
    12121 gtataggctg ggcgagtagc ggtgttgaat atgcacaagc ttaccgtgct aaattattga
    12181 gacgtacaaa tcaagacact aaatttgtgt ttttagattt tatacagtca gagaacatac
    12241 agacattaac gcaaaacatt gggtttaaag atcaagaagt tatttggttg tatcagtatt
    12301 ttagtgatat ttctatagca ccaacaacgt acacgttaga tgacgttgaa cgtgagcttg
    12361 gtcatgacat tagttttaga gaaagaaatg gtaagatagt ccgtctatat tttaatggga
    12421 aatcatcatt tgtaacatgt tatctacaaa atgaacaaaa agatgttgtg gatcgtgcag
    12481 aatttgtaat taatagtatg ttagtacgta aagattttta tagttatacg cgtatatttt
    12541 ctgagtatta tgcaccagct gataataaag cgaaattata tatgcgacaa ttctataatg
    12601 aagatggttc catcgcttat aacgaatata ttgatggaga cagctctata tatgtgtttg
    12661 aagatgcggt gttgtataac aaaaccgaat ttattgcata ctttttacaa cgattgaatt
    12721 taacccgaga cgatattgtc atattagacc gcgcttctga tattggtcag gctgttttgc
    12781 agcataaagg tgatagtaaa gttggtgttg tgattcatgc tgatcattat agtaataata
    12841 tgatgagtga gcagcatata ctatggaaca attattatga atatcaattt tcaaaagcta
    12901 aatacattga tttctttatt acagcaacag atattcaaaa tcatatggtt tgtcgacaat
    12961 ttgagcaata tcaaggttat cgcccacgtg tttatactat tcctgtggga agcattgatg
    13021 cattatcata tccaacatta tcaagaaagc catatgcgat gattagtgca tctcgtttag
    13081 caaatgagaa acatattgat tggcttgtca aagcggttat cgtggctaaa cgacaagtgc
    13141 cagaattaac atttgatatt tatggagaag gtagcgagaa gacgcgactg cgtaaaatta
    13201 ttgatacaca ccgcgcacaa gattatattc gtttactagg gcatgttaaa cttgatgaaa
    13261 tttataatga ttatgagtta tttctttctg catcaactag cgaaggtttt gggttaacac
    13321 taatggaagc ggtaggctca ggactaggta tgattggatt aaatgtgaat tatggtaacc
    13381 caacctttat tcgagatggg gaaaatggct acttggtacc ttttgatacc gatgaagata
    13441 gtgtggatga tgttgtcgca aaactagctc atgccattgt aatgtatttt aacaatggtc
    13501 cccagacacc acatgacatc tcttatgaag tggcacagca atttatgact caagatatta
    13561 ttttaaaatg ggaaacatta gttcaagagg tgctgcatga ttaaattatt tgattacttt
    13621 aacgatcatt cacgaaagtt atatgagtct tttaaagcca gtaagttgga agaagattta
    13681 acaattgtac tcaatgacaa tggcttttta ccggacgatg ttatatcacc gtatcaattt
    13741 tttgcagata atcataatac agaaaatatg aaaccacgat tttttaatca ggttactgta
    13801 ccagcttttt gggaaattaa aggtaacaac aattcggcta caattaatga tatgggacgt
    13861 ctacgaggta aaatatttta tcaaagtgga gagcgcccta gaattgttag tcgtgtcgaa
    13921 tggtttgatg accaacaacg tgtccgattt gtcgattatt attctaagaa tggtattaaa
    13981 tttgcacaaa ctgtttacga tttaaatcgt aaagcgatct tgaagaaata tatgacagca
    14041 gaaggtaaag aagtgattta tgaaaatttt gtaacatctg atgtcatatt ggattggcaa
    14101 gggaagtctt actttttccc ttcaaagctc gcattcgtat tattttttat caagcaactt
    14161 gaaattacgg aacatcattt cgttattaac tcactagccc taccattttc agtgttatat
    14221 aatttgccat caaatggtag tgatgttttg gtatggcaag aacagtgcga tggtaatgtc
    14281 ccaggaaata tgcaattgat gtgtaaaggt gatatgaaac gacattgtaa tattattatt
    14341 ccagataaaa acgaatatga aacgatgctc aatatagcag acgcaaaggt tcaatctcgt
    14401 attttacaag gcggatatct atataactat cgtagtcgta atagatatac taaagaaatt
    14461 gtaatattaa ctaactcgga tcaacttcgt aacatcaagg tattggttga aactttacca
    14521 gattttaaat ttcacatcgc tgctattaca gagatgtctg ataagctaat gcaacttgat
    14581 caatatgcta atgtgcactt atacccatct attaatatag acagggtaaa tgaactatac
    14641 cagttatgtg atatttatct tgatatcaat gagggtaatg aaattttaaa tgcggtggaa
    14701 caagcgtttg actatgagtt gttgatttta ggttatcgtc aaacagcaca ccatgctaaa
    14761 gtaacactat cagagcactt atttgagcat aatgatgaga taacaatgga gagtaaagac
    14821 caattaatac aaatgttaga gagtttgaaa gatcagcaac agtttcgaga tgctttatta
    14881 gcacaaaaag cacatgcaca cgaaatctcg cgtgaacaat tcgagcaagt ttttaaacag
    14941 gcgctcgaaa gctaaaaaga aaaagcagtc taaaataaag taccatttaa tataaaagat
    15001 ttgacgtaat atgatgttag cgacatggac aatatgatat tacgtcatgc ttgttttgtt
    15061 tacttaaata taagctaagt aataagtaaa taattactaa caacaataac tagatagata
    15121 agtgtaaatt tcttgtaaac aggtatataa tagtatgtaa ttcttttaag gaagtaagtg
    15181 agaaaggagt atgttgatgg ctaaatatcg agggaaaccg tttcaattat atgtaaagtt
    15241 atcgtgttcg acaatgatgg cgacaagtat cattttaacg aatatcttgc cgtacgatgc
    15301 ccaagctgca tctgaaaagg atactgaaat ttcaaaagag atattatcta agcaagattt
    15361 attagacaaa gttgacaaag caaatcgtca aattgagcaa ttaaaacagt tatcggcttc
    15421 atctaaagca cattataaag cacaactaaa tgaagcgaaa acagcatcgc aaatagatga
    15481 aatcattaaa cgagctaatg agttggatag caaagacaat aaaggttctc aaattgaaat
    15541 gaacggtcaa agtgatatag acagtaaatt agatcaattg cttaaagatt taaataaggt
    15601 ttcttcaaag gttgataggg gtcaacaaag tggcaaggac gatcttaatg caatgaaaaa
    15661 tgatatgtca caaacggcta caacaaaata tggagaaaaa gataatgaaa atgatgaagc
    15721 aatggtagat aaggcgttag aagacttaga ccatttgaat cagcaaatac acaaatcgaa
    15781 agatgcatcg aaagatacat cggaagatcc agcagtgtct acaacagata ataatcatga
    15841 agtagctaaa acgccaaata atgatggttc tggacatgtt gtgttaaata aatttctttc
    15901 aaatgaagag aatcaaagcc atagtaatcg actcactgat aaattacaag gaagcgataa
    15961 aattaatcat gctatgattg aaaaattggc taaaagtaat gcctcaacgc aacattacac
    16021 atatcataaa ctgaatacgt tacaatcttt agatcaacgt attgcaaata cgcaacttcc
    16081 taaaaatcaa aaatcagact taatgagcga agtaaataag acgaaagagc gtataaaaag
    16141 tcaacgaaat attattttgg aagaacttgc acgtactgat gataaaaagt atgctacaca
    16201 aagcatttta gaaagtatat ttaataaaga cgaggcagat aaaattctaa aagatatacg
    16261 tgttgatggt aaaacggatc aacaaattgc agatcaaatt actcgtcata ttgatcaact
    16321 atctctgaca acgagtgatg atttattaac gtcattgatt gatcaatcac aagataagtc
    16381 gctattgatt tctcaaattt tacaaacgaa attaggaaaa gctgaagcag ataaattggc
    16441 taaagattgg acgaataaag gattatcaaa tcgccaaatc gttaaccaat tgaagaaaca
    16501 ttttgcatca actggcgaca cgtcttcaga tgatatatta aaagcaattt tgaataatgc
    16561 gaaagataaa aaacaagcaa ttgaaacgat tttagcaaca cgtatagaaa gacaaaaggc
    16621 aaaattactg gcagatttaa ttactaaaat agaaacagat caaaataaaa tttttaattt
    16681 agttaaatcg gcattgaatg gtaaagcgga tgatttattg aatttacaaa agagactcaa
    16741 tcaaacgaaa aaagatatag actatgtttt atcaccaata gtaaatcgtc caagtttact
    16801 agatcgattg aataaaaatg ggaaaacgac agatttaaat aagttagcaa atttaatgaa
    16861 tcaaggatca aatttattag acagtattcc agatataccc acaccaaagc cagaaaagac
    16921 gttaacactt ggtaaaggta atggattgtt aagtggatta ttaaatgctg atggtaatgt
    16981 atctttgcct aaagcggggg aaacgataaa agaacattgg ttgccgatat ctgtaattgt
    17041 tggtgcaatg ggtgtactaa tgatttggtt atcacgacgc aataagttga aaaataaagc
    17101 ataattatat tgggggaaga gcatctatat attttttaag tatataagac gtcttatttc
    17161 tccttaattt attgtgaagt atatgcaaaa tgcaatgaat agattgtcca tcattttaac
    17221 gttataatga atttaacgac ttagaactac acaagtaaag gagaatgaag atgtctcgaa
    17281 aaacggcgct attagttttg gatatgcaag aaggtatagc gagtagtgta cctagaataa
    17341 aaaatattat taaagcgaat cagagagcaa ttgaagcagc aagacaacat cgaataccag
    17401 tcattttcat acgtttagtg ttagataagc attttaatga tgtctcctcg agtaataaag
    17461 tgttttcaac aattaaagct caaggatatg cgattactga agcagatgca tctacacgaa
    17521 tacttgaaga tttagcacca ctagaagatg agccaattat ttctaagcga cgctttagcg
    17581 catttacagg tagttacttg gaagtttatt tacgtgcaaa tgatattaat catttagtat
    17641 taacgggtgt ctctacaagt ggagctgtat tgagcacggc attagaaagt gtagataaag
    17701 actattatat tactgtttta gaagatgctg ttggtgatag atcagatgat aaacatgact
    17761 ttattattga acaaatttta tcacgctcat gtgacattga atccgtagag tcatggaaaa
    17821 gtagtttata attaatataa cgtcaattaa agctcggcag taatgtttga gaataagtac
    17881 atttgctcat atttataaaa tgtgtgagat gacaattgaa acgtatatga tgaggaacat
    17941 ttgaacataa aataatatat ttatataaaa cgacccgagg cgttcgaact gaatgcctcg
    18001 ggtttaattg aataagaaat cggacttatg aacagaaata tgtttaagtc cgaactcctt
    18061 gtttatactt ataaatttta cgggtttaat ataatactta tttacctgta atatatgata
    18121 attcttcagc ggcagctgca ttgatagttc tatgagaaat gatacctaat cctttaacat
    18181 tggattctga aataacgata gaaccatcac tgttaacttt ttcaacaaat gctacatgac
    18241 cgtaatgttg atctgcacca aattgtccag cctcaaatac aacagcagca tgacgttttg
    18301 gtgtatgact tacttgataa tcacggtatt gagctcgatt attccaatta tgtgcatcac
    18361 ctaaatcacc tgagatagat gtaccaaatt gtttcatacg gttatatacg taccaagtac
    18421 attggccatg tggatatggc atactatcag atacctcacg gaaaggtttg aattcatctg
    18481 atgaatcatc ataatccttg atagaacgtt catatttatc taaatctggc atgcgttcat
    18541 cgtcaaactg agttaattga tagtgtttaa taatactgtt taatttctta gcatagtttg
    18601 gatctgtagc atatgtttta gataagtgtg atgttgcatc tttataagaa tcggcttccg
    18661 atttccatgt tggtttataa attgttcgat tgccatcaat accattttta ataaggtcag
    18721 agtaatcttt tagtgattct ttcgtgcttg gatattttcg gaatccagca ttaatactat
    18781 acaattgatt accatcagct tctaatgtgt taaaaggaac agaattccct tcaaaagcac
    18841 ctttgatacc gaataaatta tggtttggtg acttagctaa agcactacga cctgagtcag
    18901 attctaagat tgcttgggca atcatgacag acgcataaat atcgttatct tgaccaatgc
    18961 gatgtgcatc tttagcaatt gatttgacaa attgacgtgt atcttttgag tcaacaacgt
    19021 taaattgtcc actatcatca ttgttagata tactaggatc tgtttcgaat aatgatgttg
    19081 cacgtgtatc cttttgatta atatcgttat tgaatgattg agcaggttta gatttatgtt
    19141 tcaattcatc ttgtgttggt aactgtggat tctttgtatt agatttttca tttttgtctt
    19201 ttttagattg agatgcgtaa tctttttgtg ttttctttgc atcttcactg tattgatcca
    19261 aaatagagtc taaagccgaa tctgacattg actgattatc tttcgatgaa gatttttgat
    19321 ttgctctatc gtcacttgct ggttgactat ttgattgatt aggttgtgtt ggctttggcg
    19381 aatttggttg cttattagat gtacttggtt ttgtattgtt tgatttaggt gctttttgat
    19441 tgtctgcttt atcttgttta gatgattgcg tatccgtgtc atttttgatg ctattgtcac
    19501 tgtttttatt cgaatcattt gttgactttt cgccattacg aggttgttcg taatcagaaa
    19561 tatccgaatt taaattgaat aagttttgga ttaaagttgt taatgagtaa ttatcatcgt
    19621 atttattttt ggttagcaat tggtttatat tggtttgtgg taaattctta taaataaaat
    19681 caatgatatt gttagagcct gaagtgctgt cgtctatagt tttaaatttt ttgtcgttat
    19741 tgtcttggct acttgtatta ttgttgtctg ctttatcagt atctttactt gtagtatcct
    19801 tagaagtttc atcatcatta gatttttttg aatcatgaga tgttgtctta gctgtagtat
    19861 ctttttgagg tgtatcagca taagcggtag gtgaaactaa agtaggtaat acgagcgtag
    19921 ttgatagcaa ataaattaaa attttatttt taggcatatt tcgtattctc ccttgaaaaa
    19981 tataataatt aagtgtgata ataaactatg atttgttata atttatcgta tgctgaaaat
    20041 agttgatagg tatcaatcga ctaaatatct tccagtaaat tgattatact aattcacaac
    20101 gcaaaaataa attaatttac aaaaaatata taaaaaatat gaataattcc tacataggag
    20161 tgtgacaatg aagaacgcat ttaaattatt taaaatggat ctgaagaaag tagctaagac
    20221 gccagctgtg tggattatct tagcaggctt agctattttg ccatcgttct acgcttggtt
    20281 taacttatgg gcaatgtggg atccatatgg caacacggga cacatcaagg tcgcagtcgt
    20341 taatgaagat aaaggcgaca caatcagagg gaaaaaagtt aatgtcggta atacgatggt
    20401 taatacactc aagaaaaata aaagttttga ttggcagttt gtaagtagag agaaagctga
    20461 tcatgagata aaaatgggta aatattttgc aggtatttac atcccatcta agtttacaca
    20521 tgaaattacc gggacactac gtaagcagcc tcaaaaagca gatgtagaat ttaaggtgaa
    20581 tcagaagatt aacgctgttg cgtctaagct aacagatact ggttcgtcag ttgtcgttga
    20641 aaaagcgaat gaacaattta ataaaacagt aactcgagca ttattagaag aagctaacaa
    20701 agcaggttta actattgaag aaaatgtgcc gacaattaat aagataaaaa atgcggtata
    20761 ttcagcagat aaagctttac ctaagattaa tgactttgcg aataaaattg tatatttgaa
    20821 taaccaccaa gcggatttag ataaatatgc caatgatttt agaaaactag gaaattataa
    20881 aggcgatatt ttagatgctc agaaaaaatt aaacgaagtc aatggtgcta ttccgcaact
    20941 taatgaaaag gctaagttga tattagcttt aaataattat atgccgaaaa ttgaaaaagc
    21001 gttaaatttt gcagctgatg acgtgccagc gcagttccct aaaattaatc aaggacttaa
    21061 cattgcgagt caaggtattg atcaagctaa tggacagtta aatgatgcca aagacttcgt
    21121 cacacaagtt agaagtagag tcggtgatta tcaagatgca attcgacgcg cgcaagattt
    21181 aaatcgaaga aaccagcaac agattcctca aaatagcgcg gcgaacaacg aaacatcaaa
    21241 tagtgcacct gcagctggta atggtgtagc atcaacgcca ccaagtgtac caagtggcga
    21301 tactgcacca aataataatg ttacgcaaaa taccgcacca aatggtaata atgcgcctgt
    21361 atcgactaca ccacaaagta caagcgggaa aaaagatggt caaagttttg cagatataac
    21421 aacaacacaa gtcagcacag ctaacgagaa cacacaaaac attacagata aagatgttaa
    21481 atcaatggaa gcggcattaa cgggctcttt attatcatta tcaaataatt tagataccca
    21541 agcgaaagcc gcacaaaaag atagtcaggc attacgtaat atttcgtatg gcattttagc
    21601 atcggacaag ccttctgatt ttagagagtc tttagataat gttaagtccg gtttagaata
    21661 cacaacgcaa tataatcaac aatttatcga tacattaaaa gagattgaga agaatgaaaa
    21721 tgttgattta tcaaaagaaa ttgataaggt aaaggcagct aataatcgaa ttaatgaatc
    21781 attaaggtta gttaatcaat taagcaatgc attaaagaat ggtagttcag gaactgctga
    21841 agctactaaa ttactagatc aactttcaaa actagattca tcattatcat catttagaga
    21901 ttatgttaaa aaagatctta acagctcttt agtatcagta tcacaacgta ttatggatga
    21961 attgaacaaa gggcaaactg cattatccaa tgttcagtct aaattaaata caattgatca
    22021 agtcattaat agtggacaag ctattttaaa aaatggtaaa acacgtattg atcgcttaca
    22081 aacagtatta ccaagtattg aacaacaata cattagtgct gttaaaaatg ctcaagcaaa
    22141 cttcccgaaa gtgaaaagtg atgtagctaa agctgctaac tttgtgcgca atgacttacc
    22201 acagttggaa cagcgattaa ctaatgcgac agcaagtgtg aataaaaatt taccaacgtt
    22261 attaaatggt tatgatcaag cagtaggatt actaaataaa aatcagccac aagcgaaaaa
    22321 ggctttatca gatttagctg atttttctca aaataaattg cctgatgttg aaaaagattt
    22381 gaaaaaagcg aataagattt tcaagaagtt agacaaagac gatgcagtcg acaaattaat
    22441 cgacacactt aagaatgatt taaaaaaaca agcgggtatt attgcaaatc ctattaataa
    22501 gaagactgtt gatgttttcc cagttaagga ttatggttca ggtatgacac cattctatac
    22561 tgcactgtca gtatgggtag gtgcactctt gatggtaagc ctattaactg ttgataataa
    22621 acataagagc ttagagccag tgttaacgac acgacaagtg ttcttaggta aggcaggatt
    22681 ctttataatg cttggtatgt tgcaagcgct cattgtatcg gttggagatt tgttaatcct
    22741 aaaagcaggg gttgagtcac ctgtattatt cgtacttata acgattttct gttcgattat
    22801 tttcaactcg atcgtatata cgtgcgtatc attacttggt aacccaggta aagccattgc
    22861 aatcgtattg cttgtattac aaattgcagg tggtggagga acattcccaa ttcaaactac
    22921 gccacaattt ttccaaaaca tttcgccata cttaccattt acgtatgcaa ttgattcatt
    22981 acgtgaaaca gtaggcggta ttgttccgga aatcttaatt acaaaattaa ttatattaac
    23041 gttatttggc ataggattct tcgttgtagg tttaatttta aaacctgtaa cagatccatt
    23101 gatgaaacgc gtatctgaaa aagttgacca aagtaacgtt acagaataaa aatgaaatcc
    23161 acacattagg gttatagctc cttaatgtgt ggatttttat gtttttagac agaagagata
    23221 gtaatttctg tcttttatgg gacgggtgtt atcattgcta ttatccagga tgacttacta
    23281 tagcactaat attaccgaca aagtgaatat cctcgtcttc cgtagttaaa ataaagctag
    23341 aaccttttgg gatgtcatag tgcttatcgt ttactgttaa agtaccagta ccatcgataa
    23401 ttgtaactaa gcaataagca tgtggtttat tgaattttaa atctccatga atatcccatt
    23461 tatatactgc aaaatattga ttatctacaa attgagttac agtgtgtgtg tcgatgtgag
    23521 ttgttatagg agtagtattt ggttcatgat tgcctaattc aatcacatct ttactttgct
    23581 ctaagtgcaa atcacgcaat tgaccatttt gatctcgtct atcatagtca taaatacggt
    23641 atgtcgtatc ggaggattgt tgtgtctcta aaattaaaat acccgaacca atggcatgga
    23701 cagtgccagc aggaacataa taaaagtcac cgggcttaac aggtatacgt ttgaaaagac
    23761 tgtcaaattc atgattatca atcatgtcta ttaacgtctg tttattatgt gcatgtacgc
    23821 catatataat ttcagcacct ggggctgcat ctaaaatata ccaacattct gttttaccta
    23881 gttcgccttc gtgttttaaa gcgtaatcat catccgggtg aacttgaaca gataatttat
    23941 cattggcatc taatacttta gttagcagag ggaaactatc tcgtgaatca ttatcgaata
    24001 attcacgatg ttgtgaccaa agttgatcta gggtcatatc cttgtatgga ccattgataa
    24061 ttgtattagg accatttgga tgtgcagaaa ttgcccagca ttcaccagtt gtttcattag
    24121 ggatatcata gttaaatgct tttaatgcat gaccgcccca aattctgtct ttaaaaacgg
    24181 gttgtaaaaa taatgccata gttaaaactc ctctatattt tcattaataa gttataaatt
    24241 tctgtagtac tgtttgcatt aattagtgat tggcgtgtct catcattcat taacgcttta
    24301 gataagcgct gaagtatttt taaatgtgta tcctgactgt tgtttggtac ggcaattaag
    24361 aatatcaatt gaggtagact accatctaga ctctcccatt taacaccatg attatttttc
    24421 ataacagcta caatcggttg ttttacaaca tcagactttg catgtggaat ggccacgttc
    24481 atgccaatag ctgtcgtaga ctccatttca cgttctagga ttgcattttt taaatgcgat
    24541 gtgtgctcta cataacggca aattttaagt ttatgaatca acatatcaat tgcttcgttt
    24601 cgagacatgt cgtgatcagt aattatcata gtttgttgat caaaaacatg agaaggttta
    24661 ttgtgatgtg aatgtttcgc ggtgttatct acattgtcaa cctctgtatc atgttgtgtt
    24721 atatctgtat catgaagttg cgtgtgttgc gctggtgcat ctactgctat aactggtgta
    24781 ttgcgtttta ataatagtac agtagtcatt gtgacaagac tacctactat cactgcaaag
    24841 ataaacaata atacatgatc aataccacct aatacagcca cgattggacc tccatgtgcg
    24901 actctatcgc cgacaccacc aatggctgca atgactgatg caatcattgc accaatgatg
    24961 tttgcaggta taatgcgcaa tggatcttgg gctgcgaaag gaatagcacc ttcagtaata
    25021 ccaaatagtc ccatagtgaa ggaagcctta cccatttctc tttcggaatg attgaattta
    25081 tacttttgaa caaacgttgc taaacctaaa ccgattggtg gtgtacatac agcaactgcg
    25141 accataccca taacggcgta attaccttca gcaataagtg ctgagccaaa taaaaatgct
    25201 actttgttta ctggaccgcc catatcgaag gcaatcatcg cacctataat catcgcaagt
    25261 ataataatat tagcaccttg catacttttt aaccaggttg ttaatgcctc aaaaatatta
    25321 gaaattggtg caccgattaa aaatataaat atcaatccta caacgaccga tgaaataatg
    25381 ggaataataa tgataggcat aattggtgcc attgcttttg gaactttaat atctttaatc
    25441 cactttgcga tataacctgc taagaaacca gcaacaatac cacctaaaaa tcctgcgcct
    25501 gcatcactgc cataaaaact accgtcagca gcgatagcgc cgccaatcat accaggaaca
    25561 agaccgggct tgtcagcgat actaacagcg atatatccag ctagtattgg aaccataaat
    25621 ttaaaggcta aactaccaat gttttcaatg gatttccaaa atgaatcatc tgggatgact
    25681 aatccttttg atgtcgtttc accgcctaga gtcagcgcga tggcgataag gagtccacca
    25741 actacgataa aaggaaccat aaacgataca ccgttcatta aatgttgata caccatttga
    25801 ataccacttt tagacttacc gcgatctttc gaatgataat ttgtttcaga ttgataaata
    25861 ggcgcatctt gattaatgat acgttgaatt agacctctcg gattatgaat cccttcgcga
    25921 acattttcat taatcaaccg tttaccaaca aatcgggaca gatcaacttg tttatcagct
    25981 gcaattatga caccatcagc ttcttcgatg tcttgcgtag ttaaaacatt ttcagcacca
    26041 acaccgcctt gtgtctctac tttaatatcc acacccattt cttttgctac ctgctcaagc
    26101 ttttcttgag ccatatatgt atgtgcaatg ccatttgggc atgaggtaat agctacaatt
    26161 ttcataaaat catctccttt tctatattgt aagcgcattc tcgatactaa aaaaaagaat
    26221 aattaccgtt actagtggca attattcttg taagtattca aataactgtt gctttaaact
    26281 atgatcatct aaattacata aatggttcac tgaatcatca tccaagttag caattaattg
    26341 catcatttgt tttgtaaaag ctgtgtcttt ttgtgaaatt gctaagaaaa agacaagttt
    26401 gacatcgtgt tgtcgccaag gaaaaacatc ttttgtgcga aaaataagca catgtgattg
    26461 taaaactttt tcaggatcac catgaggaat cgccataaaa ttacctatgt atgtagaaga
    26521 tgatttctca cgctctaaag ctgattcgat atatccttct acaatcgcat gatgtgcttg
    26581 taatattttt tgagcttctt caaaaatttg cacagtatgt cgtggttttt gttcagtatt
    26641 tacgacaagg aaattgacag tgtccatatg atgatgtgct tgaaccggat tttgcttttg
    26701 cttcacaata tgtctgattt tgtgacggtc atcctcagaa aataatggtg caaccttgat
    26761 agttgaaagg tgcttaggaa gtatgtttag cgtttgtttt ggaatatcat gggtcgttat
    26821 taataaatct acattgtcaa agtgatagtg tgttatattt tctagtttaa tcgtatttat
    26881 cactaacaac tcttcggata agttatttat tttagtttct aaaaaattcg acacacctag
    26941 accataataa caagcaatga ctacatttaa ttgtgttttg gtacgacgct cgatggcagc
    27001 ttgaaaatga atagttaaaa aagcaatttc atcttcactc atctcaatat ctgtatcaac
    27061 tgctaattta tcaatcgctt caaaaagtgt gttaaacaca aagggataga gttttttaat
    27121 ctctataact aaaggattgt ttaaataaat gttttgagtg atacgtaaat atgctttact
    27181 aaaatgatta tataaatttt gttgtaaaat cgaatcttca ttgaaaggta catgaatacg
    27241 ttgctgcatc aattcgatta agcgatcaat ataactttgt ataaatatac gttctatgcc
    27301 aatatcgagt ttattaaaat gataagcaat aaagaatgaa aacatattga ttacttgttc
    27361 gttcaagtca taacctaatc tttcgttgat ttgcttaatg caagattgag atatcaattt
    27421 tgcatcgtgg tttaacgtgt ctagctcact taaagattgc ttacgtttaa tgattaaaat
    27481 gagatgaatt aaaagctgtt gtatttgaat atcagttgtt tcaatactat gttgttgaag
    27541 tgtctcttgt ataatatgcg aaatcatcct ttggtgtgaa tcaggtaatt catttaaaat
    27601 taggtcttca acatgtacat gccctgatga taattgattt aaatggatga tggcattagt
    27661 gatatcatta tctgttccat cgaccacaat accttgtttt ttcttaattg ttaaagcgat
    27721 attaaatttt tgacaccatt gttgaatacg aatgaaatag tcgttgagca cagttttaga
    27781 taatagataa tcttgctcta gttgttgcaa tgtctgcgat ttattgtgca ttagcagttg
    27841 atacgccata gataataata gtttttcttt atatgattga atatgcgtgt aacgttcagt
    27901 tatcgtttct aaggtatact gcgatgtatt taattgatat cctttagatt taatacttac
    27961 gatgatatca tccataaaat tgctattgat aacatggata tcattgcgaa ctgtgcggtt
    28021 tgaaacattg acatgttcag caatttcatt agaactaatg tgctttgatg gatttttaat
    28081 aaaaaactgg agtagtttta agtgtctatc aagcatttaa catgtacctc ctttctaaat
    28141 tttccgtgta agcgttttta aaggtgtatt aattttatta aacatgagag cttatacata
    28201 cgtcaatgac attaaagcga acttttatat gaatttaaca gagtgcgaat tatgcaaata
    28261 aagaacagca gtaagatatt tcaaatagaa aaatatctta ctgctgtttt tctgaattta
    28321 tgtacctgat acttgtggac gtatcaggta aatgattaat ttttaggtga ttgtacttga
    28381 ggtgtttgtt tagaaggcgt attggtatta tttgatttat tagcaggtgg tgtgttctgt
    28441 tgtttatgat tttggttatt cgttgaaggt tgactgctac cgccgtgatt tgaatttgat
    28501 tgattcggat tagattgatt tgaatttgat tgattcggat tagatggttg tgtattcgct
    28561 ggtgctgttg aaccgttatt ttggacagtt gatggcgtag atgattgatt gccattagta
    28621 acaccgttgt tgttttgatt ttcatttgtg ttgtttgtat tttcgtcttt ttgatgattt
    28681 acttcagtat ctttcttttg atgggtagct ttattatctt gctcattatt atgatttgac
    28741 gatgtagaat gatttattgc agcataaatg gcgaatccaa gtgcaccaat taacaagatg
    28801 ataacaacag taataagaaa ttttttcaaa tgtaacgcct ccgtttataa taaaaatagt
    28861 catacattgc atggcatcat gctttcaatg tcgacaaaat gatgttaact ataaaacttg
    28921 aaatgcggac gatattaatg tttgtgttag tttttatgta cttcaaataa gtataacaaa
    28981 actgttatat atttataaat ataatcaata gtattttatt gtacaagcaa gttataataa
    29041 tagtaataag attgaaaaat ttgtatggaa aagagagata aatatgaatc aaacaactaa
    29101 actttgtgca gcaacgacat tagcattagg tactttaatt ggcgcaacag ttgtagggac
    29161 tgcatcacca atacatcaag aaacgcaggc ggcaacaaca ccttactata cttatcatgg
    29221 atatatcggt cataacgcta attttataat ggataagcat tttattaacg ctattaaata
    29281 tgacaacgtg acatttaatg gtattaaatt agcgaagaca aatgcgacaa aaaaagtaga
    29341 gaaatacgat caaactttta aaggtgtaac tgcaaaagga aatgaagcga atcaattaca
    29401 atttatcgtt aaaaataata tatcactaaa agatattcaa aaagcttatg gtaaagattt
    29461 gaaaaaagag aataataaaa cgaaagaatc tgatagcggt attttttatt atcaacattc
    29521 taaaaagtca ttaggcattt ggtttgttgt tgatcataat agagtggttg aagttacagt
    29581 gggacatacg ccatacaaaa cgagtaaata ataaagtaaa tataggggct agtttgtgag
    29641 gaatgatgtc acatactagt ctttttgatt atatgatggt agttttcgtg tctccatgat
    29701 attgaaatat atagatttaa tcatgcgcag ttaagtagtc agcatatata tttcacgtat
    29761 tgattaagta tgtgttgtac taattttttg attgttaata atttcacaaa aataaagcct
    29821 tgataaattt taaaatataa ttaagtgcaa ttttcaaaat tttatttagt cacagataac
    29881 atttttaaaa aagaaaagaa tcaataaata
//
LOCUS       DAPSKH010000033        29846 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPSKH010000033 DAPSKH010000000
VERSION     DAPSKH010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 29846)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29846)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29846
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.033"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(167..1171)
                     /locus_tag="RPH49_001512"
     CDS             complement(167..1171)
                     /locus_tag="RPH49_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-dependent carboxyltransferase family
                     protein"
                     /protein_id="HDY5124658.1"
                     /translation="MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRL
                     VANDKNEATLEMTNKMAKIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLK
                     FRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTAR
                     HHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVIKNKGTEDFKEDAIQRFVKHDYKV
                     TSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQI
                     GTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
                     "
     gene            complement(1155..1865)
                     /locus_tag="RPH49_001513"
     CDS             complement(1155..1865)
                     /locus_tag="RPH49_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allophanate hydrolase subunit 1"
                     /protein_id="HDY5124659.1"
                     /translation="MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIE
                     IVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYG
                     SKYGPDLESLLKHYKIKLETFIELHSKAQYFVSMMGYSPGFPYLTGLNKKLYINHTSK
                     QKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFR
                     PINENELEVGAFKDVNHN"
     gene            complement(1955..2161)
                     /locus_tag="RPH49_001514"
     CDS             complement(1955..2161)
                     /locus_tag="RPH49_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124660.1"
                     /translation="MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIATITTVISF
                     ILVYALIHELMPFVVRAMDLMYHQ"
     gene            complement(2227..2835)
                     /locus_tag="RPH49_001515"
     CDS             complement(2227..2835)
                     /locus_tag="RPH49_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class IV"
                     /protein_id="HDY5124661.1"
                     /translation="MQLFETMKIDNGHIPRLTYHTNRIKCSSERLNFKFDEHAWRNEL
                     NDVTTKYHSGQYRLKIVLNAESEFETIVSPLPEKSSFTAKFQVLPKAVNPTFINNKTT
                     ERKHLAHNHETDLILLTSEDGKVLEFDIGNIVIEEDGKWYTPSYKDDFLKGCMRDYLI
                     DSDKLVEKDFNKNELIYKYHNNEIRLFLINSLREVADVHLCL"
     gene            complement(2835..3986)
                     /gene="pabB"
                     /locus_tag="RPH49_001516"
     CDS             complement(2835..3986)
                     /gene="pabB"
                     /locus_tag="RPH49_001516"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HDY5124662.1"
                     /translation="MRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHF
                     AQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLAKDDIYAVAYSFEKAESINSTYEHQT
                     SYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLT
                     QFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQ
                     QYYKTLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVS
                     GTLKNNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDD
                     KMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML"
     gene            complement(3970..4563)
                     /locus_tag="RPH49_001517"
     CDS             complement(3970..4563)
                     /locus_tag="RPH49_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HDY5124663.1"
                     /translation="MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMK
                     PKAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVH
                     GHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDAAIIMAFEHIR
                     FPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI"
     gene            4914..5582
                     /gene="queC"
                     /locus_tag="RPH49_001518"
     CDS             4914..5582
                     /gene="queC"
                     /locus_tag="RPH49_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDY5124664.1"
                     /translation="MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQR
                     HDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARN
                     LLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHT
                     PLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLES
                     KGAL"
     gene            5584..6003
                     /gene="queD"
                     /locus_tag="RPH49_001519"
     CDS             5584..6003
                     /gene="queD"
                     /locus_tag="RPH49_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDY5124665.1"
                     /translation="MLQQIYPSTTHPYQFELNKDFNFSAAHHIPCEEAGICQNVHGHT
                     YFVNLTIVGDKLDDTGFLVNFSHLKKMIHGKFDHQLLNNLPAFKNKIPSTEIVAETIY
                     QIVKENLASLEHQPKCIQVFVRETPTSYVVFRPKEQV"
     gene            6007..6720
                     /gene="queE"
                     /locus_tag="RPH49_001520"
     CDS             6007..6720
                     /gene="queE"
                     /locus_tag="RPH49_001520"
                     /EC_number="4.3.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDY5124666.1"
                     /translation="MAKIPVLEIFGPTIQGEGRVIGRKTMFVRTAGCDYRCSWCDSAF
                     TWDGSAKGDIKLMTAEEIYDELKRIGGDLFNHVTISGGNPALIKGIQELVNLFQDKGI
                     FSALETQGSKFQPWMTQIDDLTISPKPPSSTMTPDLKKLDEVITQCVPSSLNLKVVVF
                     DDKDYDFAKMIHHRYPNIPFYLQVGNPYLSDSVDNHTEKLLERYEQLVDLVMQSNDMN
                     HVYVLPQLHTLLWSNKKGV"
     gene            6819..7403
                     /locus_tag="RPH49_001521"
     CDS             6819..7403
                     /locus_tag="RPH49_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124667.1"
                     /translation="MIVYILINIAIVILITGFNLYRHQMQHLSLSAMLLSITINAFIN
                     TFIIDKYNFITLCTITMFIIWTILQFYIDKKLKPVYITDQKFIAIILTIVVSLTQRVT
                     DFSSTQSIYMSIPFLAPAIFIIGGIMLFISTFNNLDETAENNNKIKKLMIKGLIIINI
                     SFIVMMVLTPYWYLYLIVYLIFLLFLLWQKVYKF"
     gene            7683..8123
                     /locus_tag="RPH49_001522"
     CDS             7683..8123
                     /locus_tag="RPH49_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DM13 domain-containing protein"
                     /protein_id="HDY5124668.1"
                     /translation="MNTKYFLAVGAVAAVLTLGACGNSNSQDQGNKTEQKTKSEDSNV
                     KTDKTKHLTGTFSSKNGETVEGKAEIKNGKLMLTNYKSSKGPDLYVYLTKNGDIKNGK
                     EIAMVDYDKEKQTFDLKNVDLSKYDEVTIYCKKAHVIFGGAKLK"
     gene            8467..8940
                     /locus_tag="RPH49_001523"
     CDS             8467..8940
                     /locus_tag="RPH49_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDY5124669.1"
                     /translation="MNKLLLLVTFIIRVGSGIVMLMQGYEKLTGGFTLKGLVPVIANN
                     TDSPEWYKWFFANIVAHTTSLFDIIVPLGEIAIGLGLIFGVFAYAASFFGAFVMINYI
                     LADMIFTYPLQLTFFILLLMSHSLLKQISLKEIINYFRGRKNRGEKIDDPLTDRG"
     gene            8915..9601
                     /locus_tag="RPH49_001524"
     CDS             8915..9601
                     /locus_tag="RPH49_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5124670.1"
                     /translation="MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSND
                     IDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKP
                     FSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFEL
                     LWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVW
                     GLGYKFERSR"
     gene            9601..10656
                     /gene="saeS"
                     /locus_tag="RPH49_001525"
     CDS             9601..10656
                     /gene="saeS"
                     /locus_tag="RPH49_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     SaeS"
                     /protein_id="HDY5124671.1"
                     /translation="MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLT
                     TIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSF
                     NKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIK
                     ESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHEN
                     RTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIA
                     ISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDI
                     DVGTTMTVTLHKLDITS"
     gene            complement(10728..11711)
                     /gene="csbB"
                     /locus_tag="RPH49_001526"
     CDS             complement(10728..11711)
                     /gene="csbB"
                     /locus_tag="RPH49_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoteichoic acid-specific glycosylation protein
                     CsbB"
                     /protein_id="HDY5124672.1"
                     /translation="MKIRVVIPCFNEGEVITQTHQQLTEILSQDSSVKGYDYNMLFID
                     DGSTDTTIDEMQHLATIDRHVSYISFSRNFGKEAAMIAGYQHSTEFDAVIMIDCDLQH
                     PPEYIPKMVEGFMEGYDQVIAKRDRSGENFSRKTLSHLYYKLVNCFVEEVQFDDGVGD
                     FRLLSQRAVKSIASLEEYNRFSKGLFEWIGYNTKVFTYQNVERQKGESKWSFKKLFNY
                     GIDGLISFNSKPLRMMIYLGLFIFSISVLYIIYLFINIMISGVNIPGYFSTIAAILLL
                     GGIQLISIGVVGEYIGRIYYEVKARPKYIIQATNLSSIENAEKDTHKVYSK"
     gene            complement(11843..12682)
                     /locus_tag="RPH49_001527"
     CDS             complement(11843..12682)
                     /locus_tag="RPH49_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDY5124673.1"
                     /translation="MLNEIQILNNGYPMPSVGLGVYKISDEDMTKVVNAAIDAGYRAF
                     DTAYFYDNEASLGRALKDNGVDREDLFITTKLWNDYQGYEKTFEYFNKSIENLQTNYL
                     DLFLIHWPCEADGLFLETYKAMEELYEQGKVKAIGVCNFNVHHLEKLMAQSSIKPMVN
                     QIEVHPYFNQQELQEFCDRHDIKVTAWMPLMRNRGLLDDPVIVKIAEKYHKTPAQVVL
                     RWHLAHNRIIIPKSQTPKRIQENIDILDFNLELTEVAEIDALNRNARQGKDPDDVKIG
                     DLK"
     gene            complement(12904..14253)
                     /locus_tag="RPH49_001528"
     CDS             complement(12904..14253)
                     /locus_tag="RPH49_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDY5124674.1"
                     /translation="METSTIISLIIFILLIALTTVFVGSEFALVKIRATRIEQLADEG
                     NKPAKIVKKMIANLDYYLSACQLGITVTSLGLGWLGEPTFEKLLHPIFEAINLPTALT
                     TTISFAVSFIIVTYLHVVLGELAPKSIAIQHTEKLALVYARPLFYFGNIMKPLIWLMN
                     GSARVIIRMFGVNPDAQTDAMSEEEIKIIINNSYNGGEINQTELAYMQNIFSFDERHA
                     KDIMVPRTQMITLNEPFNVDELLETIKEHQFTRYPITDDGDKDHIKGFINVKEFLTEY
                     ASGKTIKIANYIHELPMISETTRISDALIRMQREHVHMSLIIDEYGGTAGILTMEDIL
                     EEIVGEIRDEFDDDEVNDIVKIDNKTFQVNGRVLLDDLTEEFGIEFDDSEDIDTIGGW
                     LQSRNTNLQKDDYVDTTYDRWVVSEIDNHQIIWVMLNYEFNEARPTIGQSDEDEKSE"
     gene            complement(14474..15655)
                     /gene="nagA"
                     /locus_tag="RPH49_001529"
     CDS             complement(14474..15655)
                     /gene="nagA"
                     /locus_tag="RPH49_001529"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDY5124675.1"
                     /translation="MSELIIYNGKVYTEDGKIDNGYIHVKDGQIVAIGEVNDKAAIDN
                     DTTNKIQVIDAKGHHVLPGFIDIHIHGGYGQDAMDGSYDGLKYLSENLLSEGTTSYLA
                     TTMTQSTDKIDNALINIAKYEAEQDVHNAAEIVGIHLEGPFISENKVGAQHPQYVVRP
                     FIDKIKHFQETANGLIKIMTFAPEVEGAKEALETYKDDIIFSIGHTVATYEEAVEAVE
                     RGAKHVTHLYNAATPFQHREPGVFGVAWLNDALHTEMIVDGTHSHPASVAIAYRMKGN
                     ERFYLITDAMRAKGMPEGEYDLGGQKVTVQSQQARLANGALAGSILKMNHGLRNLISF
                     TGDTLDHLWRVTSLNQAIALGIDDRKGSIKVNKDADLVILDDDMNVKSTIKQGKVHTF
                     S"
     gene            complement(15963..17921)
                     /locus_tag="RPH49_001530"
     CDS             complement(15963..17921)
                     /locus_tag="RPH49_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDY5124676.1"
                     /translation="MRVTELLTKDTIAMDLMANDKNGVIDELVNQLDKAGKLSDVASF
                     KEAIHNRESQSTTGIGEGIAIPHAKVAAVKSPAIAFGKSKAGVDYQSLDMQPAHLFFM
                     IAASEGGAQTHLDALAKLSGILMDENVREKLLHASSPEEVLAIIDHADDEATKEEEAE
                     AEAQQVAAAEQSSKQSNEPYVLAVTACPTGIAHTYMARDALKKQADKMGIKIKVETNG
                     SSGIKNHLTEQDIENATGIIVAADVHVETDRFDGKNVVEVPVADGIKRPEELINKALD
                     TSRKPFVARDGNRKGHSNDNQEKLSPGKAFYKHLMNGVSNMLPLVISGGILMAIVFLF
                     GANSFDPKSSDYNAFAEQLWNIGSKSAFALIIPILSGFIARSIADKPGFASGLVGGML
                     AISGGSGFIGGIIAGFLAGYLTQGVKAMTRKLPQALEGLKPTLIYPLLTVTATGLLMI
                     YVFNPPASWLNHLLLDGLNNLSGSNIVLLGLVIGAMMAIDMGGPFNKAAYVFATGALI
                     EGNAAPITAAMIGGMIPPLAIATAMLIFRRKFTKEQRGSIIPNYVMGMSFITEGAIPF
                     AAADPLRVIPSMMIGSGIGGAIALGLGSRITAPHGGIIVIVGTDGAHLLQTLIALVVG
                     TLVSALIYGLIKPKLTETEIEASKSMDE"
     gene            complement(17927..18847)
                     /gene="pfkB"
                     /locus_tag="RPH49_001531"
     CDS             complement(17927..18847)
                     /gene="pfkB"
                     /locus_tag="RPH49_001531"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDY5124677.1"
                     /translation="MIYTVTFNPSIDYVIFTNDFKIDGLNRATATYKFAGGKGINVSR
                     VLKTLDVESTALGFAGGFPGKFIIDTLNNSAIQSNFIEVDEDTRINVKLKTGQETEIN
                     APGPHITSTQFEQLLQQIKNTTSEDIVIVAGSVPSSIPSDAYAQIAQITAQTGAKLVV
                     DAEKELAESVLPYHPLFIKPNKDELEVMFNTTVNSDADVIKYGRLLVDKGAQSVIVSL
                     GGDGAIYIDKEISIKAVNPQGKVVNTVGSGDSTVAGMVAGIASGLTIEKAFQQAVACG
                     TATAFDEDLATRDAIEKIKSQVTISVLDGE"
     gene            complement(18844..19608)
                     /locus_tag="RPH49_001532"
     CDS             complement(18844..19608)
                     /locus_tag="RPH49_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDY5124678.1"
                     /translation="MMIITEKRHELILEELSHKDFLTLQELIDRTGCSASTIRRDLSK
                     LQQLGKLQRVHGGAMLKENRMVEANLTEKLATNLDEKKMIAKIAANQINDNECLFIDA
                     GSSTLELIKYIQAKDIIVVTNGLTHVEALLKKGIKTIMLGGQVKENTLATIGSSAMEI
                     LRRYCFDKAFIGMNGLDIELGLTTPDEQEALVKQTAMSLANQSFVLIDHSKFNKVYFA
                     RVPLLESTTVITSEKALNQESLKEYQQKYHFIGGTL"
     gene            complement(19858..20340)
                     /gene="ybaK"
                     /locus_tag="RPH49_001533"
     CDS             complement(19858..20340)
                     /gene="ybaK"
                     /locus_tag="RPH49_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDY5124679.1"
                     /translation="MAKNKKTNAMRMLDRAKIKYDVHSFEVPEEHLSGVEVAELIQAN
                     VKTVFKTLVLENTKHEHFVFVIPVSETLDMKKAAALVGEKKLQLMPLDNLKNVTGYIR
                     GGCSPVGMKTLFPTVVDKSCENYSHISVSGGLRTMQITIAVEDLIAITKGKIGEVIHE
                     "
     gene            complement(20514..20966)
                     /locus_tag="RPH49_001534"
     CDS             complement(20514..20966)
                     /locus_tag="RPH49_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124680.1"
                     /translation="MTVKNLFLGFVAVILTVCLIGLLILATNEDALAKVHKTINTLNA
                     INVSTEDTYKKKMDILNIHTAKASEVNENVKKQNHFKHRVNANKSNSFNEQECQVIAD
                     RYADKHINDNYGLERISKTNHGYNYVYSNDNSTSKQHVSISNQGIITK"
     gene            complement(21263..22429)
                     /gene="norA"
                     /locus_tag="RPH49_001535"
     CDS             complement(21263..22429)
                     /gene="norA"
                     /locus_tag="RPH49_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter NorA"
                     /protein_id="HDY5124681.1"
                     /translation="MNKQIFVLYFNIFLIFLGIGLVIPVLPVYLKDLGLTGSDLGLLV
                     AAFALSQMIISPFGGTLADKLGKKLIICIGLILFSVSEFMFAVGHNFSVLMLSRVIGG
                     MSAGMVMPGVTGLIADVSPSHQKAKNFGYMSAIINSGFILGPGIGGFMAEVSHRMPFY
                     FAGALGILAFIMSVVLIHDPKKSTTSGFQKLEPQLLTKIDWKVFITPAILTLVLAFGL
                     SAFETLYSLYTSYKVNYSPKDISIAITGGGIFGALFQIYFFDKFMKYFSELTFIAWSL
                     IYSVIVLVLLVIADGYWTIMVISFVVFIGFDMIRPAITNYFSNIAGDRQGFAGGLNST
                     FTSMGNFIGPLIAGALFDVHIEAPIYMAIGVSLAGVVIVLIEKQHRAKLKQQDL"
     gene            22638..23060
                     /locus_tag="RPH49_001536"
     CDS             22638..23060
                     /locus_tag="RPH49_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDY5124682.1"
                     /translation="MKLQKSNHTILLVLEKGEDIVECITNFADDQDLTFTSVSGIGAC
                     DDVVLKFFNLTTKQYEEKHITEPLELTSLLGNISRLENGHFAHLHATFGTQSYETFSG
                     HLAKAIVSATAEIILTVTDLDIQRSFKDAVGLNLLDPQ"
     gene            23246..23863
                     /locus_tag="RPH49_001537"
     CDS             23246..23863
                     /locus_tag="RPH49_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1361 domain-containing protein"
                     /protein_id="HDY5124683.1"
                     /translation="MQSRYIARIYFLILFIVSLFETKIFQFMTLNLFLAYIPFELSLL
                     LRLFKPNKKYEWPLFIIYSFIFVLLLPNTFYMVTDLIHLNQFQFNFYAGLNLSEWKYF
                     TYLLLGVFLAVYVMILIYFEILTLTSHRWLNRLIVVVLMFLNGFGIYIGRFLRLHSVY
                     FFNEPLHVLNHILESLTLKTAMFVCFMVVMQAAILLFGKGVRLNK"
     gene            23860..24144
                     /locus_tag="RPH49_001538"
     CDS             23860..24144
                     /locus_tag="RPH49_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000154460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124684.1"
                     /translation="MTINIIVLIVSIIVFQLIIGHIWHDIGLSYLRSILLMMLPFGLG
                     VFIQQVSYYERQYPKWQVPQNIKVRLKYIYLATFLEYVVLYLTLFTDILR"
     gene            complement(24299..25672)
                     /locus_tag="RPH49_001539"
     CDS             complement(24299..25672)
                     /locus_tag="RPH49_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDY5124685.1"
                     /translation="MAIAVLLNRMFRMEHNPLFEYIYQQKEDIDACYFIIPEEDMSSA
                     SDLKAQFYRGTLQRFYQSLHAEKLTPYVMSYDDIISFCKENNISEVVIAGDIMSYHLE
                     EYDILHQRSLFNEARIAVTLIRGNHYFKASKTMNQQGEPYKVFTSFYKKWRPYLRHRD
                     VYHYDLKSFEDFVIASPDDLVFDDITFGSSQIIEQNKWQHFLDQDIQNYESGRDYLPE
                     VLTSQLSVALAYGLLDIIEIFNDLLARYDEDEANYEAFIRELIFREFYYVLMTQYPET
                     SYQAFKPKYRQIKWSQNEANFNAWCEGQTGFPIIDAAIMELTQTGFMHNRMRMVVSQF
                     LTKDLFIDWTWGEKFFRKHLIDYDAASNIHGWQWSASTGTDAVPYFRMFNPIRQSERF
                     DAKALYIKTYLPIFNQIDAKYLHDTQRNESNLFEQGIELGSHYPRQMVDHQEKRTQVL
                     ATFKALD"
     gene            complement(25758..27311)
                     /locus_tag="RPH49_001540"
     CDS             complement(25758..27311)
                     /locus_tag="RPH49_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DASS family sodium-coupled anion symporter"
                     /protein_id="HDY5124686.1"
                     /translation="MSEEKHVVEHEQQKKEKTKKQYKPFWIVMSFIILIVVLLLPAPS
                     SLPIMAKAVLAILAFAVIMWVTEAVSYPVSATLIIGLMILLLGFSPVQNLGEKLGNPK
                     SGSAVLAGSDLLGTNHALTLAFSGFATSAVALVAAALFLAAAMQETNLHKRLALLVLS
                     IVGNKTRNIVIGAIIVSIVLAFFVPSATARAGAVVPILLGMIAAFKVSKDSKLASLLI
                     ITSVQAVSIWNIGIKTAAAQNIVAINFINHQLGFDVSWGEWFLYAAPWSIVMSIALYF
                     IMIKVMPPEINTIEGGKDLIKEELHKLGPVSAREWRLIVISMLLLLFWSTEKVLHPID
                     SASITIIALGVMLMPKIGVMTWKHVENKIPWGTIIVFGVGISLGNVLLKTGAAQWLSD
                     QTFGVLGLKHLPIIATIALITLFNILIHLGFASATSLSSALIPVFISLTSTLHLGDQS
                     IGFVLIQQFVISFGFLLPVSAPQNMLAYGTGTFTVKDFLKAGIPLTIVGYILVIVFSM
                     TYWKWLGLL"
     gene            complement(27594..27881)
                     /locus_tag="RPH49_001541"
     CDS             complement(27594..27881)
                     /locus_tag="RPH49_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124687.1"
                     /translation="MTNEDKRFEQLRFERKFIVIPYLIYAVIVLLLNIFYSDLKITMT
                     LFGLFFAYNVVILFIAFIKHYKRTLLLSLILTVLSGAAFFGIIYVYGINHF"
     gene            complement(27916..28824)
                     /locus_tag="RPH49_001542"
     CDS             complement(27916..28824)
                     /locus_tag="RPH49_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDY5124688.1"
                     /translation="MEQIMINHYVHFSRLVQGFWRANEWKMTAKELNYFINELVERGI
                     TTMDHADIYGDYQCESLFGNALDLSPELRNKIQIVTKCGIILPSKQFDFTNGHRYDLS
                     SKHIVKSVEQSLINLNVDYLDSLLIHRPSPLMDPEQVADALTKLVKQGKLKSFGVSNF
                     NHSQYQLLNQYIMKERLHISINQLELSPYHVDSLQDGTMDSMYQNHVQIMAWSPFAGG
                     KIFDKEDIKAQRIMKVVQSIADKYGVSDTAVMIAWLVKIPHRIMPILGTSQLKRIDQA
                     IEGLQLNLDDQSWFDIYTAIIGQDIP"
     gene            complement(28927..>29846)
                     /locus_tag="RPH49_001543"
     CDS             complement(28927..>29846)
                     /locus_tag="RPH49_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDY5124689.1"
                     /translation="NKDEKIRISIINGFLGSGKTTLLTHYISELLKNDEKIKIIMNEF
                     GTFDIDSNSISNEIEVHSLINGCVCCDLKQELVYELKAIALKGDVNHVIIEATGIAHS
                     LELLVACQDPQIVNFFEKPIIYGVLDATRFLERHQYTENTVSLMEDQLKLSDMIIINK
                     IDLVTDDSLEKIDKQLSIICASIPTYKTTYGQVSLEELDLPGKDREISSHHHHHHGIK
                     SMTYTFTGPIDRQLFYQFIMKLPESVLRLKGYVSFRDQPNAIYEFQYAYGLPDYGIIG
                     MHLPLTIVIIGETLDTNHIRNQLDMLQFT"
BASE COUNT         9915 a         5368 c         4206 g        10357 t
ORIGIN      
        1 gagtaatttt agtcaaaatt caagtaaaaa cacactttat cttttcattt tactgtgaaa
       61 cgaatttgaa tatgatacat ttcgcagata aaacacagta ttatttcatt atacattagg
      121 aggaaattat ttgcatcgga ctcgagtatg agctacgtac caaatattat ttcatcattt
      181 ctaattgcat tctatattct attccatgga ataattgatt taaccagtta ctatacttaa
      241 caaggttctt ttcagccgtt aaaatatcta taaattgaaa tttcaaacgt gatccttgcg
      301 gtttttgtgc taatttcgtt aaatgataac ttgcgattgt accgatttgc ggatagctac
      361 ctagcgtata atgatcattt aataagataa taggtgtgcc atcacgctta atttgtatcg
      421 ttcctttttt gacagtctga tacggtggca tatcttcata aaaggctttg attttttcac
      481 cttcaagcat catccccatg cgatttgctt tgctcgttac tttataatca tgtttcacaa
      541 atctttgaat ggcatcttct ttaaaatctt ccgtaccttt atttttaatg acatgaaata
      601 catcagacat ataattaaat gacaaggcgt atccatcaat accccaatct gtttgtttcg
      661 tgtgagcaag gttttcaaat aacttatgat gacgagctgt ataatctctc ttaagcttta
      721 tttcatcgcc atcttgtaat gttcttcctt taaaaccacc aatttttaca ttaaagtcgg
      781 ttgaattaga tcctaaccat gcatctaatt caaatccgcc tcccacagct aaatacactc
      841 gcgatgtata acttgtttct ctaaacttta aaacatcgcc tttatctaac aaatacaatt
      901 tatatggaga tatagtcata tgctcagtgt atgctttgac attaccccct gctaatgcaa
      961 tcagcgtagg ttctgtaaaa cgaatctttg ccattttatt agtcatttcc aaagttgctt
     1021 cattcttgtc attagcaact aatcgattag caatttcatg tgctaaagta tcaagtgcac
     1081 cacatggaat tacaccatca tgttcatatc cccttctacc aaagtcctga aagctactga
     1141 ataagccact tttttcaatt atgattgaca tctttaaacg ctcctacttc taattcattt
     1201 tcattgatag gtctaaattt aatattatcg cctaacttta agcgtgcgaa atctgattct
     1261 ttcggattaa aaagtgataa tggtgtataa ccaataacta accaatcatt aattgtatcc
     1321 gttgttacaa taccgcattt tttcccttca agtactacag aaccagctgg aatgaatttt
     1381 ttctgtttac tcgtgtgatt aatatacaat ttcttattta atccagttaa ataaggaaac
     1441 ccaggtgaat atcccatcat cgaaacaaaa tattgcgcct tagaatgtaa ttcaataaaa
     1501 gtttctagct tgattttgta atgttttaaa agtgattcta aatccggacc atatttcgaa
     1561 ccatacacaa ttggtatttc aatcaaatct tgctggttaa aatcatgttt tatgtttaaa
     1621 tgaatcgatt ctattagtgc tttcatgtat aaaaaaggtg attgtatatt atggtgttta
     1681 atcatatccc ttgcgtcata gacaatcatc atgtctgatt ctgatggcac aatttctata
     1741 ataaatggat aattttgttc aattaaatat gagcgaagtg ttaataaatc ttcggttaaa
     1801 cttttagata cttctttttc aattgcgact acaatggctt ggtcaccttg actatatatt
     1861 ttcatttgta cacctcttca atatttggtt actttacttt catttttaat taatagaatc
     1921 gattgaatag ttcattttat ctactcaact aaatttactg atgatacatt aaatccattg
     1981 ctcgcacaac aaaaggcatg agttcgtgaa ttaatgcata tacaaggata aagcttataa
     2041 cagtagtaat tgttgctatc aaacgaacaa catatattct attttcagat agcaatcgat
     2101 tcactaatcg ataatttacg tatacaagaa ttaacaacag cacaatataa acaataatca
     2161 tatttggccc catttaattt ttaaatttgt tttcacttcg ttttctacat tattatcata
     2221 ctaattttaa aggcaaaggt ggacatcggc aacctctcgt aaactattta tcaaaaataa
     2281 acgtatctca ttgttatgat atttataaat caattcgttt ttattaaagt ctttttcaac
     2341 aagtttgtca ctatctatta aataatcacg catgcatcct tttaagaaat catctttata
     2401 acttggtgtg taccattttc catcctcttc aatgacaatg ttgccaatat caaattcaag
     2461 gaccttgccg tcctctgaag ttagcaatat taaatctgtt tcatgattgt gtgctaaatg
     2521 ctttcgttct gtcgttttat tatttataaa agttggatta actgctttgg gcaacacttg
     2581 aaattttgct gtaaaactac ttttctcagg taaaggtgac actatcgttt caaattcgct
     2641 ttcagcattt aatacgattt taagtctata ttggccactg tgatactttg ttgttacatc
     2701 gtttaattca tttcgccatg catgttcatc aaatttaaag tttaatcgct cagaagaaca
     2761 ttttatgcga ttagtatgat aagtaagtct agggatatgt ccattatcaa ttttcattgt
     2821 ttcaaataat tgcattataa catctccaaa atcttggttt ttgcgtaaaa ttcatttact
     2881 tcatcttttg gcttagaatc aattgtaata cctgctccga ctccataaat cgcttgtcca
     2941 tatttatact caatagtacg aattggaata ttaaaaatca ttttatcatc ttcagttgga
     3001 agtaatagtc caattgctcc gcagtatata ccacgaggtg aactttctaa ttgtttaata
     3061 tatttcattg tattcagttt cggtgcacct gttatcgaac cacaaggaaa taacgatgtt
     3121 aaaatttgag ttaagtctgt attatttttt aaagttccac ttaccatcga agtcatttga
     3181 aatacagttt tatatgcctc aataaaaaat agtttataca ccttaattga gccactctgt
     3241 gatattctcc ctatatcgtt tcttagtaaa tcaacaatca tgacattttc tgcacgatct
     3301 ttcgaagaag tttgcaatgt tttataatac tgttgatctt cagcttccgt ttttcctcta
     3361 ggcattgtcc ctttcatcgg tttgcttatg ataacgttat cgacattgtt aaattgtcct
     3421 ttttgaaaaa ataattctgg tgagatagac gctacttgga tttcatctgt ttgtaataac
     3481 gcagtataat taccattact aaattgagtt aatcgttcat ataaagtact aataggataa
     3541 taaatgttat ctgttaagcg cgccgtatag ttcacttgat acgtttcgcc ttcgacaatt
     3601 gcttgttgga cacgtttaat attagtcatc ataacctcag aagattcaac aaatgaaaaa
     3661 tgatgctttg atacataaga agtttgatgt tcatatgttg aatttatgct ttccgctttt
     3721 tcaaaactat aagctactgc ataaatatca tctttagcta atgaatgtgt acacataaca
     3781 tgattaaaat actttgccgc ttcgtaactt aaatataacg agacatatct accttgtcgt
     3841 tgctgcgctt gtgcaaagtg tatcacttct cccacatcag ccaacttagt agcaacatac
     3901 ttctttataa atccctttaa ttgaatatgg tattgcttat attcattttc agttaaatag
     3961 tagcgataat tatattctat tctcacagta atcacctacc ttcgataaaa ataattcaac
     4021 ttgtcgataa ccgtattcac tcaaaataga ttcaggatga tattgcacac caaaaaccgg
     4081 aaatctaata tgctcaaatg ccataataat cgctgcatcg ttttttgctg taatctttaa
     4141 gcaatttgga aaagtcgctc cgtcagcaat taatgaatga taacgcatta cattgaaatt
     4201 ttgaggcagt ccttgaaaaa taccttcatt ggtatggcgt aactgtgtag tatgtccgtg
     4261 tacaggatga tagccgtgaa tgatatttcc accaaaataa gacacgatac attgaaatcc
     4321 taaacataca cctagtatag gtacacgctg ataaaattgt tctaacactt cattcaagat
     4381 aggataatca tccggattac ccggcccagg tgaaataaca attgcttttg gcttcatatt
     4441 aatgacgtct tctatcagca gattatcaat accaacaact tgaactgtta gtttcgtttg
     4501 agtcttaata tagtctatta aattatatgt aaatgaatca ttattatcta tgactagaat
     4561 cattgtatac tccgttctaa atgtgtttta tttttataat atgtattgga tgtagctaaa
     4621 actttaaaag cattgtcatt atcctgacct tgattttaac taatatatgg tatattctat
     4681 tcatcgtaca taaatgaata tcagaggttc ctagctgaaa ccctctataa aaaactagac
     4741 attgaaattt caaacattcg ttggtaaacc tttaatatat attataggag caacccattt
     4801 ctttcgtcta tcttttatgg agataggctt tttttatttt ataaattaaa aacgggctta
     4861 tcaatgccat taacctcttt attaatatta ttaatgatag gagcaattac aaaatggaaa
     4921 gtgtattaaa taatgaaaaa gccatcgttg tctttagtgg tggtcaagac agtacaacat
     4981 gtctctttta tgcaaaaaaa catttcaaag aagttgaact cgtaacgttt aattatggcc
     5041 aaagacatga tactgaaatt gaagtcgcaa aacaaattgc acaagatcaa ggaatgaaac
     5101 atcacgtttt agatatgtca ttattatcac aacttactcc aaacgcatta acacaacatg
     5161 atatggaaat tactaataat gaagatggta tacctaatac atttgttcca gctagaaatt
     5221 tacttttctt gtcgtttgca ggcgctctag cttatcaaat tggggctaag catattatta
     5281 caggcgtatg tgaaacagac ttttcaggct acccagactg tcgcgatagt tttataaaat
     5341 caatgaacgt aacattaagc ctagctatgg acaaagattt tgtcattcat actcctttaa
     5401 tgtggttaaa caaagcagaa acgtggaaat taagtgatga actcgaagtt ttagattata
     5461 ttcgtacaaa aacattaaca tgctataacg gtatcattgg ggatggctgt ggtgaatgtc
     5521 cagcttgtca tttacgtcaa cgtggactaa atcaatatct tgaaagtaaa ggagcgcttt
     5581 aaaatgttac aacaaatcta tcctagtaca acgcatccat atcaattcga attaaataaa
     5641 gattttaatt tttcagctgc acatcacatt ccatgtgaag aagcaggtat ttgtcaaaat
     5701 gtccatggtc atacttactt tgttaattta acaattgtcg gtgataaact agatgacact
     5761 ggcttcttag tgaactttag ccatttgaaa aagatgatac acggtaaatt tgaccatcaa
     5821 ctgttaaata acttacctgc ttttaaaaac aaaatccctt caactgaaat cgtagcggaa
     5881 acaatttatc aaattgttaa agaaaatttg gcatcgctcg aacaccaacc aaaatgtatt
     5941 caagtatttg taagagaaac accaacaagt tatgtcgtat ttagaccaaa ggaacaggtg
     6001 taactaatgg ctaaaattcc tgtactcgaa atattcggcc caaccattca gggtgaaggt
     6061 cgagtaatcg gtagaaaaac gatgtttgtg agaacagctg gatgtgatta tcgctgtagc
     6121 tggtgtgatt ctgcatttac ttgggatggt agtgctaaag gcgatataaa actcatgacc
     6181 gctgaagaaa tttatgatga attaaaacgt attggtggcg atttatttaa ccacgttaca
     6241 atttctggtg gtaacccagc attaattaaa ggtatccaag agttagttaa cttatttcaa
     6301 gataaaggta ttttcagcgc actggagaca caaggcagta aattccaacc ttggatgaca
     6361 caaattgatg atttaacgat tagtccaaaa ccaccaagtt caactatgac accagattta
     6421 aaaaagttag atgaagtgat tacacaatgt gtaccttcct cattaaactt aaaagtagtt
     6481 gtattcgatg ataaagatta tgattttgcc aaaatgatac accaccgtta tccaaatatt
     6541 cccttctatt tacaagttgg taacccatat ttatcagaca gcgtagataa tcataccgaa
     6601 aagttgttag aacgctacga gcagttggtg gatttagtta tgcaaagtaa tgatatgaat
     6661 cacgtttatg tgttaccaca acttcataca ttactttgga gtaataaaaa aggtgtataa
     6721 aggataactt attttacttt ttacaagtca tatctaatga ataacaatat attaattgat
     6781 ataatagttg attgaagtat aacgaacagg agtccatcat gattgtatat atattaatta
     6841 atattgctat cgtcatactt ataactggat tcaatttata taggcatcaa atgcaacatt
     6901 tatcattaag tgcaatgttg ttatctatta cgataaacgc ctttataaat acattcataa
     6961 ttgataaata taactttatt actctgtgta ctataacaat gtttatcatt tggacgatac
     7021 tacagtttta cattgataaa aaattaaaac ctgtatacat tacagaccaa aaatttattg
     7081 ctatcatatt aacgattgtt gtcagtttaa cacaacgtgt taccgacttt tcaagtacac
     7141 aatcaatata tatgtctatt ccatttttag cccctgccat tttcatcatt ggtggtatta
     7201 tgttgtttat ttcaacattt aataacttag atgaaactgc tgaaaataat aacaaaataa
     7261 agaaactaat gattaaagga cttatcatta ttaacatttc atttatcgtt atgatggttt
     7321 taacaccata ttggtacttg tatttaatcg tctatcttat tttcttgttg tttttattgt
     7381 ggcaaaaggt ttataaattt taataccaaa actataaaac acttctgata ttcttagttc
     7441 gatatatcag aagtgtttta tagtgataac tagtttagat aaatattttc ttacttaaaa
     7501 aaccgccctc ttcttatttt gcctcctatt tatttaaatc agacaattat tttcattttc
     7561 aaattattct ttcttcaata ttagttaagc gatatttaaa cgaagttaag aattagttaa
     7621 tggcatatta tttgccttca ttttaaactt aacttatcaa attgaagaaa tgaggagtta
     7681 gcatgaatac aaaatatttt ttagcagttg gtgctgttgc cgctgtatta actttaggcg
     7741 cttgtggtaa ttctaattca caagatcaag gtaacaaaac tgaacaaaaa acaaagtcag
     7801 aagacagcaa tgttaaaact gataaaacaa aacacctaac aggtacattc agttctaaaa
     7861 acggtgaaac tgttgaaggt aaagctgaga ttaaaaatgg taaattaatg cttactaact
     7921 acaaatcatc aaaaggtcca gatttatacg tctacctaac aaaaaatggc gacattaaaa
     7981 acggtaaaga aatcgcaatg gttgactacg ataaagaaaa acaaacattt gatcttaaaa
     8041 atgtagattt aagcaaatat gatgaagtaa caatctattg taaaaaagct cacgtcatct
     8101 tcggcggcgc taaattaaaa taatcaattt ctgagttaaa cttttattta caacatacta
     8161 ttactataca ttacaaattt taaaaatata cattacactc attactcaat ggaaagcgta
     8221 tgatttcaca gcccccccct agcttgtaga aatcatactt tccttttttc aatatatata
     8281 caactattaa atcccataag attgtagagc acataagtaa atatttttag agcttgaggt
     8341 ttgtttagct taagcagccc atgagctcaa acacttcctg ttcacataac actacaaatc
     8401 gcattatgtt gcttaatctt atgtttatat aaattacaca caataaatag aaagaatgtg
     8461 aacatcatga ataaattatt gctactcgtt acatttatca ttcgtgtggg ttcaggtatt
     8521 gttatgttaa tgcaaggcta cgaaaaatta acgggcggat ttacgctgaa aggtttagtc
     8581 ccagtcatag ctaacaatac tgattcacca gagtggtata agtggttttt cgcaaatata
     8641 gttgcacata cgacgtcatt atttgatatt attgttccac ttggagagat tgcaattgga
     8701 ttaggtttaa tttttggagt ttttgcatat gctgctagtt tctttggagc ctttgttatg
     8761 ataaattata tcttagcaga tatgatattt acgtatcctc ttcaattaac tttctttatc
     8821 cttttactaa tgagtcactc attgttaaaa cagatttcac ttaaagaaat cattaattac
     8881 tttagaggtc gtaagaacag aggtgaaaaa atagatgacc cacttactga tcgtggatga
     8941 tgaacaagac attgtagaca tttgtcaaac ctattttgaa tatgaaggtt acaaagtaac
     9001 aacgacaact agcggtaaag aagcaatttc tttactatca aatgatattg atatcatggt
     9061 acttgatatc atgatgccag aagttaatgg ttacgacatt gtcaaagaaa tgaaaaggca
     9121 aaaattagat atccccttta tctatttaac tgccaaaaca caagaacatg ataccattta
     9181 cgccttaact ttaggtgcag atgactatgt caaaaaacca tttagtccaa gggaactcgt
     9241 tttacgtatt aataatttac ttacaagaat gaagaaatac catcatcaac cagttgaaca
     9301 actgtcgttt gatgaattaa cacttattaa cttaagtaaa gttgtgactg taaatggtca
     9361 cgaagtccct atgcgtatta aggaatttga gttattgtgg tatttagctt ctagagaaaa
     9421 tgaagttatt tctaaatcag aattacttga aaaagtttgg ggatatgact attacgaaga
     9481 tgctaatacc gtgaatgtcc atatacaccg tattagagaa aaattagaaa aagagagctt
     9541 tacaacatat accatcacaa ctgtatgggg attaggatat aaatttgaaa ggagccgata
     9601 atggtgttat caattagaag tcaaatcatt attggcgtcg tatcgagtat actattaact
     9661 tcaactattt tagcaattgc atatatttta atgtggttta acggccatat gacactaact
     9721 ttgaccttaa cgacaataat tacaagctgt ttaaccttat taatatgtag tatttttatt
     9781 aatccactta tacaaaaaat taagcagttt aatataaaaa ctaagcaatt tgctaacgga
     9841 aattacgcaa gcaatgataa aacgtttaat tcaccaaaag aaatttatga attaaatcaa
     9901 tcttttaata aaatggcttc tgaaattacg caacaaatga atcaaattaa atccgaacaa
     9961 caagaaaaaa cagaactgat tcaaaactta gcccatgatt taaaaacacc tttagcaagc
    10021 attatttcat attctgaagg actacgtgat ggtataatca caaaggatca tgagattaaa
    10081 gagtcatacg acatattaat taaacaagca aacagattat caacattatt tgatgatatg
    10141 actcatatta tcactttaaa tacaggtaaa acatatcccc cagaattaat acaactagac
    10201 caattacttg tatcaatatt gcaaccatat gagcaacgta tcaaacatga aaaccgcaca
    10261 ttagaagtga atttctgtag cgaaattgat gcattttatc aatatcgaac gccacttgag
    10321 cgtattttaa caaacttact tgataatgcg ctaaaatttt caaatgttgg tagtcgcatt
    10381 gatattaata ttagtgaaaa caaagatcaa gatactatcg acattgctat tagcgatgaa
    10441 ggtattggca ttataccaga actacaagaa cgtatattcg aacgtacatt cagagtagaa
    10501 aactctcgta atacaaaaac gggtggttct ggattaggct tatatatagc taatgaactc
    10561 gcgcaacaaa ataacgcaaa aatcagtgta agcagtgata tagatgtagg aactacgatg
    10621 actgtgacat tacacaaatt agacattacg tcataatccg atttatttat aaaataaaat
    10681 gcaaagacta aaaagaagct cccattaatg agggcttctt tttttgttta tttagaataa
    10741 actttatggg tatccttctc agcattttca atacttgaaa gatttgtagc ttgaataata
    10801 tatttaggac gtgccttaac ttcataatat atcctgccaa tatattcacc tacaacacca
    10861 attgaaatta actgtatgcc gcctaataat aaaatagctg caatcgttga aaaatatccc
    10921 ggaatattaa caccagatat cataatattg atgaataaat agataatata tagaacgctt
    10981 attgaaaaga taaataaacc aagataaatc atcattctca aaggtttact attaaaggaa
    11041 atcaatccat caataccata attaaataac tttttaaatg accatttaga ttcacctttt
    11101 tgtctctcaa cattttgata cgtaaacact ttagtattat agcctatcca ttcaaataac
    11161 ccttttgaaa atcgattata ttcttcaagt gatgcaatgg atttaacagc tctttggctt
    11221 aaaagtctaa aatcaccaac accatcatca aattgtactt cttctacaaa gcaattaact
    11281 aacttataat acaaatggct taatgttttg cgactaaaat tttcaccact tctatcacgc
    11341 tttgcaatca cttgatcata gccttccata aaaccttcaa ccattttcgg aatatattca
    11401 ggtggatgtt gcaaatcaca atctatcatg atgactgcat caaattcagt actatgctgg
    11461 taacctgcaa tcatagctgc ttcttttcca aaatttctac taaaagaaat atagctgaca
    11521 tgtctatcta ttgtggcaag atgttgcatt tcatctatag tggtatccgt actaccatca
    11581 tctatgaaaa gcatattata atcatagcct ttcacactac tatcttgtga aagtatttca
    11641 gttaattgtt gatgtgtttg tgtaatgact tccccttcat taaaacaagg aatgacgact
    11701 ctaattttca tctatgtcca tcctttttat ttaaaagatt ttgaatgtac ctgagtattg
    11761 ttttatcaaa tagtaaaaac caactcattt attttaatgt acacattaaa aggcattcat
    11821 aaacgtaaaa tttaacatcc agttatttta aatccccaat tttcacatca tctggatctt
    11881 taccttgtct tgcatttcta tttaaagcat caatttcagc tacttctgtt aattctaaat
    11941 taaaatctaa aatatctata ttttcttgaa tgcgtttagg tgtctgagat tttggaataa
    12001 taattctatt gtgtgctaaa tgccaacgca atacaacttg tgctggtgtt ttatgatatt
    12061 tttcagcaat tttaacaatg acagggtcgt ctagtagtcc tctatttctc atcaaaggca
    12121 tccatgcagt cactttaata tcgtgacgat cacaaaattc ttgtaattct tgttggttaa
    12181 aatatggatg tacctcaatt tgattcacca ttggtttgat acttgattga gccattaatt
    12241 tttctagatg atgaacatta aaattacata cacctattgc ttttacctta ccttgctcgt
    12301 aaagttcttc catagcttta tatgtttcta aaaatagacc atctgcttca caaggccaat
    12361 gtattagaaa taaatcaaga taattagttt gtaaattttc aatcgatttg ttgaaatatt
    12421 cgaatgtttt ctcataacct tgatagtcat tccataactt cgttgttata aacaaatctt
    12481 ctctatcgac gccattatcc tttaatgctc gacctagtga agcctcatta tcataaaagt
    12541 atgcagtatc aaacgctcta tagcctgcgt caattgcagc atttacaact ttagtcatat
    12601 cttcgtcaga gattttataa acacctaatc caactgaagg catcgggtat ccattattta
    12661 atatttgtat ctcattcaac atctttatat ctctccaatc tatgtatctt ttatatcttt
    12721 acattaccct aattttttca acaaactcaa ttaatacgaa ttatcgcttt caataaaaaa
    12781 tattcattaa atcattaaag atattaagtt ccaatactat tttcactttt cattaatttt
    12841 agtcaaaaaa ataaccaacc aaaaatgaat taaatcattc ttagttggtt tatatattat
    12901 tatctattct gatttttcat cttcatcaga ctgtccgata gtaggtctcg cttcattaaa
    12961 ctcatagttt aacatcaccc aaataatttg gtggttatcg atttctgaaa caacccagcg
    13021 atcataagtt gtatccacgt aatcatcttt ttgtaagttg gtattacgag attgtaacca
    13081 tccacctatc gtatcaatat cctcagagtc atcaaattct ataccgaact cttcagttaa
    13141 atcatccaat agtactctac catttacttg gaatgtctta ttatcaattt taacgatatc
    13201 attcacttca tcatcatcaa attcatcacg aatttcccca acgatttctt ctaaaatatc
    13261 ttccatcgtt aaaatacctg ccgttccacc atattcatct ataataagac tcatatgtac
    13321 atgttcacgt tgcattctaa ttaatgcatc actgatacgt gttgtctctg aaatcattgg
    13381 caactcatgt atatagtttg ctattttaat agtttttcca gaagcatatt cagttaaaaa
    13441 ttctttgacg ttaataaatc ctttaatgtg gtctttatca ccatcatcag taattggata
    13501 acgcgtaaat tgatgttctt ttattgtttc tagtaattcg tctacattaa aaggttcatt
    13561 tagtgtaatc atttgagttc taggtaccat tatatctttt gcatgtcttt catcgaatga
    13621 aaagatattt tgcatatacg ccaattcagt ttggttgatt tctccaccat tataactatt
    13681 gttaataata attttgattt cttcttctga cattgcatcg gtttgggcat caggatttac
    13741 accaaacatt ctaataataa cacgtgcaga accattcatc agccaaatca atggtttcat
    13801 aatgttaccg aaatagaaca atggtcttgc atatactaaa gcaagctttt cagtatgttg
    13861 aatcgctata gatttaggcg ctaattcacc aagtactaca tgcaaatacg taacgattat
    13921 aaatgatact gcaaacgaaa tcgtcgtcgt taatgcagtt ggtaaattga ttgcttcaaa
    13981 tatcgggtgt aatagctttt caaacgttgg ttcaccaagc caacctaacc ctaaagatgt
    14041 tactgttata cctaactgac aagcagaaag ataataatct agattagcaa tcatcttttt
    14101 tactatttta gcaggtttat ttccttcatc tgctagctgt tcaattcttg ttgctctaat
    14161 ttttactaat gcaaattctg aaccaacaaa tacagtggtt aatgcaatta atagaataaa
    14221 tataatcaaa ctaattatgg tcgaagtttc caattaattc cctatttcta gggattcacc
    14281 tccatgttat atgtgtcact catgggtaac acgcattcaa atttatcact atgacttaaa
    14341 ttacaactac atgttatcgc cttcccattt agacaccccc agaaaaaaat gttattgctt
    14401 ctattttatc ataatataaa gtgcttatgt taacagatta aatctattgc atacatttaa
    14461 ttatgattat ctattagcta aatgtgtgaa ccttaccttg ttttattgta gattttacat
    14521 tcatgtcatc atctagaata acaaggtctg catccttatt tactttaata ctaccttttc
    14581 tatcatcgat acctaatgca atggcttgat ttaaacttgt tacacgccat aaatgatcta
    14641 atgtatcacc tgtaaatgat attaagttac gtaacccatg attcattttt aaaatactac
    14701 cagcaagcgc accatttgca agacgtgctt gttgtgattg aacagttact ttttgtccac
    14761 ccaaatcata ttctccttca ggcatacctt ttgcacgcat tgcatctgta attaaataaa
    14821 aacgttcatt acctttcata cggtaagcaa ttgcaaccga tgccggatga gaatgtgtgc
    14881 catcaacaat catttcggta tgtagagcat cattcaacca tgctactcca aaaacacctg
    14941 gttctctatg ttggaatggc gtcgctgcat tatataaatg cgtgacatgt ttagctcctc
    15001 gctcaacagc ttcaactgct tcttcgtatg ttgccactgt atgaccaatt gaaaaaataa
    15061 tgtcatcttt atacgtttca agcgcttctt ttgcaccttc aacttcaggt gcaaacgtca
    15121 taatctttat taatccgtta gcagtctctt gaaaatgttt aattttatcg ataaatggac
    15181 gtacaacgta ttgcggatgt tgagcaccaa ctttattttc agatataaat ggcccttcca
    15241 aatgtatacc tacaatttcc gctgcattgt gaacatcttg ctccgcttca tatttagcaa
    15301 tatttataag tgcattatct attttatcag tagattgcgt cattgtagtg gccaagtatg
    15361 atgtcgtccc ttcagacaac aaattttcgg atagatattt taagccatcg tatgacccat
    15421 ccattgcatc ttgaccataa ccaccatgaa tatgtatatc aataaaacct ggtaatacat
    15481 gatgaccttt agcatcaatc acttgaattt tatttgtcgt atcattatca attgctgctt
    15541 tatcatttac ttctccaatt gcaacaatct gtccatcttt cacatgaatg taaccattat
    15601 cgattttgcc atcttcagta taaactttgc cgttatatat aattaattct gacacgtata
    15661 aacccttctt tatttataaa ttttcacttt aagacactca tattttacta tatctgcttc
    15721 gtttggcata actttttgca aaatattaaa aaagtctata catttgtggt gtctatttct
    15781 tcattcattt atctaaaaat aaaaacacct tcatatcaat tcataaaaac tgaattaata
    15841 gaaagtgttt ttacagcttt atataaacta ccgttaacac gataaataaa actaacatat
    15901 attcattgaa catacaactt aatatgaagc tctttgctaa caatcatttt aaatcattaa
    15961 aactattcgt ccattgattt tgaagcttcg atttctgttt cagttaactt tggtttaata
    16021 agtccataaa ttagcgctga aactaatgta cctactacaa gtgcaataag tgtttgcagt
    16081 aaatgtgcac catccgtacc gacaattacg ataataccac cgtgtggcgc agtaattcga
    16141 gaacctaaac ctaaagcgat tgcgccacct atacctgacc caatcatcat tgaagggata
    16201 acacgtaatg gatcggcagc cgcgaatggg atcgcacctt ctgtaataaa ggacataccc
    16261 atcacatagt tagggataat tgaaccacgt tgttcttttg taaatttacg tctgaaaatt
    16321 aacatcgctg tcgcaattgc taacggtgga atcataccac caatcattgc agctgtaatt
    16381 ggtgctgcat taccttcaat caacgcacct gttgcaaaaa catatgccgc tttgttgaat
    16441 ggaccaccca tatcaatcgc catcatagcg ccaataacta aacctaataa tacaatatta
    16501 gaacctgata aattgtttaa tccatctaat aacaaatgat ttaaccaaga tgctggtgga
    16561 ttaaagacat aaatcatcaa taatcctgta gctgtcactg ttaatagtgg gtaaattaat
    16621 gtcggcttta atccctctaa tgcttgtggt aacttacgtg tcatggcttt aacaccttgt
    16681 gttaagtaac ctgctaagaa acctgcaata ataccaccaa taaatcctga accacctgaa
    16741 attgctaaca taccacctac aagacctgac gcgaatccag gtttatctgc aatactacgt
    16801 gcaatgaaac cagataaaat tgggataatt aatgcgaatg cacttttact accgatattc
    16861 caaagttgtt ctgcaaacgc gttataatct gaacttttcg gatcaaatga gtttgcacca
    16921 aataaaaaca cgattgccat taaaatacca ccagatatta caagtggtag catgttagaa
    16981 acaccgttca ttaagtgttt atagaatgct ttacctgggc ttaatttttc ttggttgtca
    17041 tttgaatgac cttttctgtt accatcacga gcaacaaaag gtttacgact tgtatctaat
    17101 gctttattaa ttaattcttc tggtcgttta ataccgtctg cgactggtac ttctacgaca
    17161 tttttaccat caaatcgatc cgtctcaaca tgaacatctg cagcaacaat gatacctgtt
    17221 gcattttcaa tatcttgttc agttaaatgg tttttaatac cgcttgaacc attcgtttct
    17281 actttaattt taatacccat cttatccgct tgctttttca atgcatcacg tgccatatat
    17341 gtgtgtgcaa tacctgttgg acaagcagtt acagctaata catatggctc attagattgt
    17401 ttagatgatt gttctgcagc tgcaacttgt tgtgcttcag cttctgcctc ttcttctttt
    17461 gtcgcttcat catcagcatg atcaataatt gctaacactt cttctggaga cgatgcatgt
    17521 aataatttct cacgaacatt ttcatccatt aaaataccag atagtttagc taaagcatct
    17581 aaatgtgttt gggcaccacc ttctgacgct gcaatcataa agaataagtg tgctggttgc
    17641 atatccaaac tttgataatc tacgcctgct ttagatttac caaatgcaat agctggtgac
    17701 ttaactgctg ccactttggc atgtggaata gcaatacctt caccgatacc agttgtactt
    17761 tgtgattctc gattgtgaat cgcttcctta aatgacgcga catcacttaa tttacctgct
    17821 ttgtctaatt gatttactaa ctcatcaata acaccatttt tgtcatttgc cattaaatcc
    17881 attgctatcg tatcttttgt taataactct gttactctca ttattttcac tccccatcaa
    17941 gtacgctaat cgtaacttgt gattttattt tttctatagc gtcccgtgtt gctaagtcct
    18001 catcaaatgc cgtggcagta ccgcatgcaa ctgcttgttg gaatgctttt tcaatcgtta
    18061 aacctgaagc aattccagcc accatgcctg caactgtact atcaccagag ccaactgtat
    18121 taaccacttt cccttgtgga ttaactgctt taatactgat ttctttatca atataaatag
    18181 caccatcacc gccaagtgag acaataacag attgcgcacc tttatcaact aacaaacgac
    18241 catatttaat aacatctgcg tctgagttca ctgttgtatt aaacatcact tctaattcat
    18301 ctttattagg tttaataaat agtggatgat atggtaaaac gctttcagcc aattcttttt
    18361 cagcgtcgac tactaattta gcacctgtct gtgctgtaat ttgtgcaatt tgcgcatacg
    18421 catcgcttgg aatactactt ggtacacttc cagcaacaat aactatatct tcgcttgttg
    18481 tatttttaat ttgttgtaac agttgttcaa attgtgttga cgttatatga ggaccaggtg
    18541 cattgatttc tgtttcttgt cctgttttta atttcacatt aatacgtgta tcttcatcaa
    18601 cttcaataaa attcgattga attgcactgt tatttaatgt atctataatg aatttcccag
    18661 gaaatccacc tgcaaatccc aaggcagttg actcaacatc caatgtcttt aaaacacgtg
    18721 agacattaat accttttccc ccagcgaatt tatatgttgc tgttgctcta ttcaaaccat
    18781 caattttaaa atcattcgta aaaatgacat agtcaattga aggattgaaa gtcactgtat
    18841 aaatcataaa gtccctccta taaagtgata cttttgttgg tattctttta acgattcttg
    18901 atttaatgct ttttcagatg tgatgacggt cgtactttct agcaaaggta cacgagcaaa
    18961 atatacttta ttaaacttag aatgatctat aagtacaaat gattgattgg ctaatgacat
    19021 tgctgtttgt ttaactaatg cctcttgctc atcgggagta gttaatccaa gttcaatatc
    19081 taatccattc atcccgataa aagctttatc gaaacaatat cgtcttaata tctccatggc
    19141 acttgaacca atcgtagcaa gtgtattttc tttaacttga ccacctagca taattgtttt
    19201 aatacctttt ttaagtaaag cttctacatg tgttaaacca ttggttacca caatgatatc
    19261 tttcgcttga atatatttaa ttagctccaa tgtagatgaa ccagcatcga taaataagca
    19321 ttcattatcg ttgatttgat tagctgctat tttagcaatc attttctttt catcgagatt
    19381 agttgctaat ttttcagtta aattcgcctc aaccatacga ttttctttta acattgcacc
    19441 accatgcaca cgttgcaatt tccctaattg ttgtagttta gataaatctc ttcgtattgt
    19501 tgaagcactg cagccagttc gatctattaa ttcttgtaaa gtcaaaaaat ctttgtgcga
    19561 aagttcttct aatattaact cgtgtctttt ttctgtaatt atcatcatca ccccatctca
    19621 ctctgtatta taatgagtac gctttcactt ttcaatcata aattaccaaa aacaatcaaa
    19681 aacaaccaaa ttgtgacgat aaaattacat ttttatattc aaatactcat ttgtaatgac
    19741 tgtttatgat cgtaatatgc taattcaatc aaaaaggagt gtggcagaaa tgaattttat
    19801 aaaaatttca tctctgtcac actcctaatc ttgccccata ctttttgttg ttattaatca
    19861 ttcatggata acttctccaa ttttgccttt agttattgca atcaaatcct caacagctat
    19921 tgtgatttgc attgttcgaa gcccaccact cacactgata tgactataat tttcacagga
    19981 tttgtcaacg actgttggaa acaatgtttt cataccaaca ggcgaacacc caccacgaat
    20041 gtatcccgtt acatttttca aattatctaa aggcataagc tgcaatttct tctctccaac
    20101 caaagcagct gcctttttca tatctaaagt ttcacttact gggataacaa atacaaaatg
    20161 ttcatgtttt gtattttcta gaacaagcgt tttaaatact gttttaacat ttgcttgtat
    20221 gagttctgcg acttctacac ccgataaatg ttcttctggt acctcaaagc tatgaacatc
    20281 gtatttaatt tttgcacgat caagcatacg catcgcgttc gttttcttat ttttagccat
    20341 ttcaacacct catttatact tcttcagaac tatattaaca ttttaaaata cattacggat
    20401 tggttgattt tgacataaca tttacatcat ttaataagtt gagttcacct tttcaaatta
    20461 aattattgca aaataaaaac agtatatcca attagaatac actgttccat ctattatttc
    20521 gttattatgc cttgatttga aatacttaca tgttgcttac tagttgaatt atcattggaa
    20581 tacacataat tatatccatg atttgtctta gaaattcttt ctaaaccata attatcattg
    20641 atatgcttat ctgcataacg atcagcaata acttggcact cttgttcgtt aaaagaattt
    20701 gatttatttg cattcacacg atgcttaaaa tgattttgct ttttcacatt ttcattcact
    20761 tcagatgctt tagcagtatg aatattgaga atatccattt tctttttata agtatcttca
    20821 gttgatacat ttatcgcgtt aagtgtatta atcgttttat gtaccttagc aagcgcatct
    20881 tcatttgttg ctaatattaa taaaccaatt aaacaaacgg ttaatattac agcaacaaag
    20941 cctaaaaata aattttttac tgtcatcccc ttacccacat ttccttactc attttttatc
    21001 atcttaacac attaatgtta atgaattagg tatgtggatt gcaatttaaa aagaatgtaa
    21061 tatttgtaac atgtttatta ctcaaaatca ttttttgtta catataacat ttaaatataa
    21121 agactaaaac atttaaaagt ttttaatctt tataaatgta aagcatcgac ttttcttcac
    21181 tataattgta agaaaatcga tgcttatttt gaaatgcttt agttgtcgaa atacattaat
    21241 cgaatgacaa ccatgtgcga tattacaaat cttgttgttt taacttagct ctatgttgct
    21301 tttcaattaa aacaataaca acacctgcta atgacacacc tatagccata taaattggtg
    21361 cttcaatgtg tacatcaaat aacgcacctg cgattaaagg acctatgaaa ttacccatac
    21421 tagtgaatgt cgagtttaac ccacctgcaa atccctgtct atcaccagca atatttgaga
    21481 aataatttgt aatagcaggt cttatcatat cgaacccgat aaagacaaca aagctaatta
    21541 ccataattgt ccagtaacca tcggcaataa ctaatagcac taatacaata actgaatata
    21601 ttaatgacca tgcaataaat gttaactcag agaagtattt cataaattta tcaaagaaat
    21661 aaatttggaa aagtgcacca aagataccgc cacctgtaat tgcaatcgaa atatctttag
    21721 gtgaataatt tactttatac gatgtatata aagaatacag tgtttcaaat gccgataaac
    21781 cgaacgctaa gacgagcgtt aaaattgctg gcgtaataaa gactttccaa tcaattttcg
    21841 ttaacaattg gggctcaagt ttttggaaac cacttgtcgt agactttttc ggatcatgaa
    21901 tcaatacaac tgacattatg aaagctaaaa tgcctaatgc acctgcaaaa taaaatggca
    21961 tacgatgtga aacttctgcc ataaatccac caatccctgg tcctaaaatg aatccagaat
    22021 tgataatcgc tgacatgtag ccaaagtttt ttgctttttg atggcttggt gaaacatctg
    22081 caatcaaacc tgtcacacca ggcattacca taccagcact cataccacca atcactctcg
    22141 ataacatcaa taccgaaaaa ttgtggccaa ctgcaaacat aaattctgac actgagaata
    22201 aaattaaccc tatacatata attaatttct tccctaattt gtcagctagc gtaccaccaa
    22261 acggcgatat aatcatttga gataacgcaa aagcagcaac tagtaatcct aaatcactac
    22321 cagttaatcc caaatctttt aaataaacag gcaagactgg tattactaaa ccgataccta
    22381 aaaaaatcaa gaaaatatta aaatataaga caaaaatctg tttattcata tgctcacctc
    22441 ttttttctcc atgtcatgct taaagctgtt attcttcttt tccacgacag attgcaattc
    22501 atgctaaata ttcgtaaaaa gtttctatat tgtattacaa cattgctaca tttgacaata
    22561 ttttttcttt gtaattatca ctattttcca tttaattgta taattaatga catattaaaa
    22621 taaaggggat tgatcatatg aaattgcaaa aaagtaatca tactatacta ctagtgttag
    22681 aaaaaggcga agatatcgtt gaatgtataa caaactttgc agatgaccaa gacttaacat
    22741 ttacatctgt cagcggcatt ggtgcgtgtg atgacgtcgt tttaaaattt ttcaatttaa
    22801 caacgaaaca atacgaagaa aaacatatta ctgagccact ggaattgacg agcttattag
    22861 gtaatatttc tcgtctagaa aatggtcatt ttgcacattt gcatgctact ttcggtactc
    22921 aatcatatga aacttttagc ggacatctcg ctaaagcaat tgtttctgca actgctgaaa
    22981 tcattcttac tgtaactgat ttggacattc aacgttcatt caaagatgca gtcggtttaa
    23041 atttacttga tcctcaatag cactttactt tttagttgaa tcaaatttta ttacaagtta
    23101 tcataagtgc ttaatcataa atgcattctc gtttattaat atacttcaac gagttaaatt
    23161 aaatttttaa ttaggaattg aatgcgttta taactatcac atttgaatga ataacttttt
    23221 cattagaaag tagtgtttat tattgatgca atctcgatac atcgctagaa tttacttttt
    23281 aattttattt atcgtctccc tttttgagac taaaattttt caatttatga ctttaaattt
    23341 gtttttagca tatatacctt ttgagcttag tctattatta cgattattca aaccgaataa
    23401 aaagtatgaa tggccactat ttatcatata tagttttata tttgtgttac ttttaccaaa
    23461 tacattttat atggtaactg atttaatcca tttgaaccaa tttcaattca acttttacgc
    23521 aggactaaat ttaagtgagt ggaaatactt tacctattta ctgcttggtg tcttcttagc
    23581 ggtttatgtg atgattttaa tctattttga aatactaaca ttgacttctc accgttggct
    23641 taatagatta attgttgtcg tgctaatgtt tttaaatgga ttcggaattt atattggtcg
    23701 tttcttacgc ttacattccg tttatttctt taatgagccc ttacatgttc taaatcacat
    23761 tctagaaagt ctaacgctta aaactgctat gtttgtatgt tttatggttg tcatgcaagc
    23821 agcaattcta ttatttggaa aaggagtgcg tttgaacaag tgacaataaa tataatcgtt
    23881 ttaatagtat ctatcattgt ctttcaattg attattggac acatatggca tgatattggt
    23941 ttaagttatt taagaagtat cttactcatg atgctgccat ttggactagg tgtatttata
    24001 caacaagtgt cgtattacga acgacaatat cctaaatggc aagtgcctca aaacataaaa
    24061 gttagattga aatatattta tctcgctacg tttttagagt atgtcgtact atacctcact
    24121 ttatttacag acatactaag ataacatcaa attaataaga aaactaaata caacttatat
    24181 atttgaggaa agccaatttc tatcacatca ataatagaaa ttggcttatt tatattgctt
    24241 aagaacttta tattctgctc cagattttac tcatgccaga tctatcaatt gagccgaatt
    24301 agtctagcgc tttaaatgta gctaaaactt gtgtacgttt ttcttgatga tctaccattt
    24361 gtcttggata atgactacct aattcaatcc cctgttcaaa aaggttggac tcattgcgtt
    24421 gtgtatcatg caaatatttt gcatcaattt gattaaaaat cggaagatat gttttgatat
    24481 acaaagcttt agcatcaaag cgttcactct gtcttattgg attaaacatt ctaaaatacg
    24541 gcactgcatc cgtacctgta gaagcagacc attgccatcc atgaatattt gatgctgcat
    24601 catagtcaat aaggtgcttt ctaaagaatt tttctcccca tgtccaatct ataaataaat
    24661 ctttggttaa aaattgcgac acaaccattc tcattcgatt atgcataaaa ccagtttgtg
    24721 tcaattccat tattgctgca tcaatgattg gaaatcctgt ttgcccttcg caccatgcat
    24781 taaaattcgc ttcattttgc gaccatttta tctgtcgata tttaggtttg aaagcttggt
    24841 atgaggtttc aggatactgt gtcattaaca cataataaaa ttctctaaaa atgagttcac
    24901 gtataaatgc ttcatagttt gcctcatctt catcataacg cgccaataaa tcattaaaaa
    24961 tttcaataat atctaataat ccatatgcta aagcaacact tagctgactt gttaacactt
    25021 caggtaaata gtctcttccg ctttcgtaat tctgtatatc ttgatctaaa aaatgttgcc
    25081 atttattctg ttcaattatt tgtgaggatc caaatgttat gtcatcaaac actaaatcat
    25141 caggtgatgc aatgacgaag tcttcgaatg attttaaatc atagtgatat acgtctctat
    25201 gcctcaagta aggtcgccat tttttataga aactagtaaa aactttgtat ggctcccctt
    25261 gttgattcat tgttttactc gctttaaagt aatgattccc acgtattaaa gtaacggcaa
    25321 tacgtgcttc attgaataaa gaacgttgat gtaaaatatc atattcttca agatgataac
    25381 tcataatatc acccgcaatc actacttcag atatattgtt ttctttacaa aatgaaatga
    25441 tatcgtcata agacatgaca taaggtgtga gcttttctgc gtgcaacgat tggtaaaagc
    25501 gctgcaaagt accgcgataa aactgtgctt tcaaatcaga agctgaagac atgtcctctt
    25561 ccggaatgat aaaataacat gcatcaatgt cttctttttg ttgataaata tattcaaata
    25621 atggattgtg ttccattcga aacattcgat ttaataacac agcaattgcc ataaacaaaa
    25681 cacccttcaa ttatcttttt attttattaa gctttttgtc actttaaaat aacctagatt
    25741 cttaattata tttttaatta aagcaaacct aaccatttcc aataagtcat actaaaaact
    25801 atcactagaa tataccctac aattgtcaat ggtatacctg ccttcaagaa atctttaacc
    25861 gtaaaagtac cagtgccata agccaacata ttttgaggtg cactaaccgg taataagaac
    25921 ccaaagctaa taacaaattg ttgaattaaa acaaatccta tagactggtc tcctaagtgt
    25981 aacgtagagg ttagcgaaat aaaaacaggt attaaggctg atgataaact tgttgcactc
    26041 gcaaagccca aatgaatcaa tatattaaaa agcgtgataa gtgcaattgt cgcgataata
    26101 ggtaaatgtt ttaaacctaa aacaccaaaa gtttgatcac ttaaccattg agctgcacct
    26161 gttttcaaaa gaacgttacc taatgaaata cctacaccaa acacgataat tgttccccat
    26221 ggtattttat tttcaacatg tttccatgtc atgacaccaa ttttcggcat taacataaca
    26281 cctaaagcaa taatagtaat ggatgcagag tcaatcggat gtaatacttt ttcagttgac
    26341 caaaacagta ataataacat ggatataaca attaaacgcc attcacgtgc gctaacgggg
    26401 ccaagtttat gcaattcttc ttttattaaa tctttgccac cttctattgt attgatttct
    26461 ggaggcatca ctttaatcat gatgaaatat aaagctatgg acataactat ggaccaaggc
    26521 gctgcatata agaaccactc gccccatgaa acatcaaatc ctaattgatg gtttataaaa
    26581 ttaatcgcta cgatattttg tgctgccgcc gttttgatac caatattcca aattgacaca
    26641 gcttgtactg aggtaattat taataaagac gctaacttgc tatctttgga aactttaaat
    26701 gccgcaatca tacccagcaa gattggtaca actgcccctg ctctagctgt tgcagaagga
    26761 acgaaaaatg caagtacaat tgaaacaata attgctccaa taactatatt tctagtttta
    26821 ttaccaacaa ttgataacac taaaagagct agtcttttat gcaaattcgt ttcttgcata
    26881 gcagcagcca aaaataatgc ggctgcaacg agagctacag ctgaagttgc aaatccacta
    26941 aacgctaatg ttaatgcatg attagttcct agaaggtcac ttccagctaa aacagcactg
    27001 ccacttttcg gattacctag cttctcccct aaattttgaa ccgggctaaa tcctaaaagt
    27061 aatatcatta agccaataat taaagttgct gacaccggat atgatacagc ttccgttacc
    27121 cacataataa ctgcaaaagc taaaatagct agtactgcct tagccattat tggcagactt
    27181 gaaggtgccg ggagtaatag tacaactata agtattataa aactcatgac aatccaaaat
    27241 ggcttgtatt gcttttttgt cttttctttc ttttgttgtt catgttccac tacatgtttt
    27301 tcttctgaca taacagtcac ccctttgttt aatcttaatt taattataac aattttttaa
    27361 aacatacatt tttaatttat gcaaaataca caattttatc gaaatatttt gtaaataata
    27421 ttgctaggtg atgagttatc tcggttaatt acaaaacgat atctaagttt aaatattaga
    27481 tcataaaaaa actatctact gaatatcctc atagcatcat ttttctaagc aaaagttaaa
    27541 cttagttaga taaaatgcaa atgagattat tgtagatagt ctctttttaa tatttaaaaa
    27601 tgattaatgc cataaacata aataattcca aagaatgccg cgccactaag cactgttaat
    27661 ataagactta gtaacaatgt gcgtttataa tgtttaataa atgctatgaa caaaatgact
    27721 acattatacg caaagaaaag tccgaataat gtcattgtta ttttcaaatc agaatagaaa
    27781 atatttaata gtaatacaat gactgcataa attaaatacg gaataactat aaatttgcgt
    27841 tcaaatctta attgttcgaa acgtttatct tcgtttgtca tgatatgctc ctttatgatt
    27901 taaaagtaaa taagtttacg gaatatcttg tccgataata gcggtgtaaa tgtcaaacca
    27961 cgactgatca tctaaattaa gttgtagccc ttcgattgct tgatcaatac gctttaactg
    28021 acttgttcca agtatcggca tgatacgatg cggtattttt actaaccatg ctatcatcac
    28081 agctgtgtca ctcacaccat atttgtcagc tattgattga acaactttca taatacgttg
    28141 cgctttaata tcttccttgt cgaaaatttt accgcctgca aaaggactcc aagccataat
    28201 ttgaacatgg ttttgataca ttgaatccat tgttccatct tgtaaactat caacgtgata
    28261 tggcgataat tctaattgat tgatgctaat atgtagtctt tctttcataa tatattgatt
    28321 taacaattgg tattgtgaat gattaaaatt cgacaccccg aatgacttca acttaccttg
    28381 tttaacaagt ttagttaatg catcagcaac ttgttctgga tccatcaatg gtgaaggacg
    28441 atgaatgagt agactatcta aataatctac attcaaattg attaatgact gttcaacaga
    28501 tttcacgatg tgcttactac tcaaatcata acgatgtcca tttgtaaaat caaattgctt
    28561 agaaggcaaa atgataccac atttcgtaac aatttgaatt ttatttctta attcgggtga
    28621 taaatccaaa gcattaccaa acagtgattc acattgataa tccccataaa tatcagcatg
    28681 atccatcgtg gtaatcccac gttcaactaa ttcatttata aaataattta actctttcgc
    28741 agtcatcttc cattcatttg cacgccaaaa accttgtaca agcctagaaa aatgaacata
    28801 gtgattaatc attatttgtt ccatatctca tccactccat ccctcaatgt cacaaaatat
    28861 tcacaataaa agtattaaga aattaatgtg ctatttccgt taaattgaaa caacacattt
    28921 tctgatttac gtaaattgta gcatatccaa ttgattacgt atgtgatttg tatctaaagt
    28981 ttcaccaata ataacaatcg ttaatggtaa gtgcatgcca attattccat agtctggtaa
    29041 accatatgca tattgaaatt cataaattgc atttggttga tctctaaatg atacataacc
    29101 tttcaaacgt agaacagatt ccggtaattt cattataaat tgataaaaca attgacgatc
    29161 aatcggacct gtaaatgtgt aagtcatact tttaatccca tgatgatggt gatgatgaga
    29221 cgatatctct ctgtctttac caggtaagtc caattcttcc aacgaaactt gtccataggt
    29281 tgttttataa gttggaatac ttgcacaaat tatacttaat tgcttatcaa ttttttcaag
    29341 actgtcatca gttacaagat caattttatt aataataatc atgtcactta gtttcaactg
    29401 atcttccatc agcgaaactg tattttcggt atattgatga cgttccaaaa atcgagtcgc
    29461 atctaataca ccataaataa ttggtttttc aaagaaatta acgatttgcg gatcttgaca
    29521 tgcaactagt aattccaaag aatgcgcaat gcctgtcgct tctatgatga catgattaac
    29581 gtcccctttt aaagcaatgg cttttagttc atagacaagt tcttgtttaa gatcgcaaca
    29641 aacacaacca ttaatcaatg aatggacttc aatttcattt gaaatactat tgctatcaat
    29701 atcaaaagta ccgaattcat tcatgatgat tttaattttc tcatcatttt ttaataattc
    29761 actaatataa tgtgtcagta acgtggtttt accactaccc aaaaatccgt taattatgga
    29821 tattcttatt ttttcatctt tattat
//
LOCUS       DAPSKH010000034        29719 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPSKH010000034 DAPSKH010000000
VERSION     DAPSKH010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 29719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29719
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.034"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..242
                     /locus_tag="RPH49_001544"
     CDS             <1..242
                     /locus_tag="RPH49_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HDY5124690.1"
                     /translation="NIGQRRLFEWLRQNGFLIKRKGVDYNMPTQYSMERELFEIKETS
                     ITHSDGHTSISKTPKVTGKGQQYFVNKFLGEKQTS"
     gene            258..455
                     /locus_tag="RPH49_001545"
                     /pseudo
     CDS             258..455
                     /locus_tag="RPH49_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500713.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            486..626
                     /locus_tag="RPH49_001546"
     CDS             486..626
                     /locus_tag="RPH49_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124691.1"
                     /translation="MLQKFRIAKEKNKLKLKLLKHASYCLERSNNPELLRAVAELLKK
                     VN"
     gene            complement(641..1273)
                     /locus_tag="RPH49_001547"
     CDS             complement(641..1273)
                     /locus_tag="RPH49_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124692.1"
                     /translation="MYIDPLKNVRFSINNVISNVEISKSMAIKQSLKPKYQLDIINRN
                     NINLFSDFKVDFHLNNLIEMNFNLRNSFSSLTFQRNLFSEETIKSFKELYRFDDEIVL
                     QAQQTIRDFYINPTAISTLAEAINSTYPINEQSTYKRHDEFVKRIENDFPHPFKKLIR
                     WSNGIAAGADIQIFVTNYINENDLHIQNSLIVAIVCLLSFLSTYCSHSKK"
     gene            1332..1652
                     /locus_tag="RPH49_001548"
     CDS             1332..1652
                     /locus_tag="RPH49_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HDY5124693.1"
                     /translation="MPHILNVTVPIPETHVLITKDEYDELIGYSLDPVWNMSDLKKKL
                     KIASDETIKDRLLFHPRFEKELRAQGIVHYPDENFNRWRFNARKMNKFVDEHFNEIYK
                     ERIK"
     gene            1649..1810
                     /locus_tag="RPH49_001549"
     CDS             1649..1810
                     /locus_tag="RPH49_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 domain-containing protein"
                     /protein_id="HDY5124694.1"
                     /translation="MSNIYKSYLVAVLCFTVLAIVLMPFLYFTTAWSIAGFASIATFI
                     FYKEYFYEE"
     gene            1903..2163
                     /locus_tag="RPH49_001550"
     CDS             1903..2163
                     /locus_tag="RPH49_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1108 family protein"
                     /protein_id="HDY5124695.1"
                     /translation="MYYKIGDVCQKVINVDGFDFKLAVKKQDYSILVNVLDLEDRFID
                     GINITDENDLYTALDILNQSIYEWIEENTDERDRLINLVMRW"
     gene            2172..2435
                     /locus_tag="RPH49_001551"
     CDS             2172..2435
                     /locus_tag="RPH49_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001638663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124696.1"
                     /translation="MRDTERNILNIFKTLFDEYTLSNQRALLEIERNHHGYLSINFLH
                     YHDSYKTNNKLVQIHEINPDSHERIKNLIIEVLRGHRKIKKGA"
     gene            2444..4387
                     /locus_tag="RPH49_001552"
     CDS             2444..4387
                     /locus_tag="RPH49_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDY5124697.1"
                     /translation="MKINKLTISNFAGIKEEKFNFDGKDAKIYGNNATGKTTTATALQ
                     WLLFDKGLDGSTKSFNPVPLNEKNEENYELIPTVFAEFEIDGKITTFKKESHPKYTIN
                     QKTNRKEYSRSRTKKQYINDESIKVKDYKARIDELIDEDVFKLITNPQAFNLLDWKKR
                     RSLLFEIAKPINDEDVIKTNDDFKELNNILGDHEIETKKKILTDKIKQINKDIKDIPI
                     RINQTQQNKQDVPEFDNDRYAIIKQEIEQLENERIDIQNGAEEINLRNQLADKQSELK
                     RIEDNNSASNENKIHTLTNELHVENGTVANLKTRLNQNKQQIAHEENRRNQLLENHKG
                     LKSDLEKAKNQKFEYLDDNVCSCCGQQLPAEQVNEAREKALQKFNASKSKELETIQTS
                     INHIISEGKKIKPIIEKLEDDNNNLQIKINEAEERSARIQNKINKLKTTHVDVTQTDE
                     YKAVMLEINEINQKRSNIRKTIQDKVSGIDDKISELTQEKSEIEVSRSIEKSNKHLDD
                     VISELRNEEDRLLDEKEKYSHDLYILKEFTTTKVKMLTENINNEFEIAEFKLFNTLVN
                     GELEETCSTTVNGVEYDSGLNNASRINVGLDIINTLSKHFKVTAPIFIDNAESVTELI
                     KTESQQIQLIVNEQDKKLRMETI"
     gene            4389..5309
                     /locus_tag="RPH49_001553"
     CDS             4389..5309
                     /locus_tag="RPH49_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HDY5124698.1"
                     /translation="MTENNKLQTIEQQLVQEKNVSDNVLNKVRVLESQGNLELPNDYS
                     PSNAMKQAWLQISQDNKLMSCNDTSKANALLDMVTQGLNPAKNQCYFIPYGNKMQLQR
                     SYHGNVMMLKRDAGAQDVVAQVIYKGDTFKQEMGETGRIKAIKHEQDFFNIDKENIIG
                     AYCTIVFNDGRDNYIEVMTIEQIKQAWMQSSMIKDEKALQNSKTHNNSKEEMAKKTVI
                     NRAAKRYINTSTDSNLFKYAQESEQRQRKEVLDAEVEENANQEQLDFEQPVLEEAQYT
                     ELENDKPIDVSDFEEIKEPATEKESEEEPF"
     gene            5375..6007
                     /locus_tag="RPH49_001554"
     CDS             5375..6007
                     /locus_tag="RPH49_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001796827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDY5124699.1"
                     /translation="MLEAGIKFERVQKHFKYKTRHIAGCLITHEHGDHAKYTKQFVDN
                     GVISYMTAGTQQAMNFESHRLCTIKAKQELRIGTWSILPFDIEHDANEPVAFLLQSTL
                     GYKVLYVTDTKYLKYKFNGITHMMLEVNYIYEQIQENIKNGSVHSTLANRIMESHFSL
                     EHAIGMLKANDLTRLEEIHLIHLSSQNSNAKYIKSEIQKVTGVPVYVGGL"
     gene            6008..6478
                     /gene="ssb"
                     /locus_tag="RPH49_001555"
     CDS             6008..6478
                     /gene="ssb"
                     /locus_tag="RPH49_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDY5124700.1"
                     /translation="MINRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGER
                     EADFINVIVFKKQAENVNKYLSKGSLTGVDGRLQTRNYENKEGQRVYVTEVIADSIQF
                     LEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIEIDDDDLPF"
     gene            6508..7401
                     /locus_tag="RPH49_001556"
     CDS             6508..7401
                     /locus_tag="RPH49_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HDY5124701.1"
                     /translation="MTGWISIDRSIQNHWLFKEKRTFSKFEAWIYLLMEANHSKAKVP
                     IGNQIVTVERGQRLTSILTLSDLFNWSRFKVKTFLDLLESDGMLEVKTTSKYTLITIV
                     NYDFYQSEQGRNQHQNDIKPTSKQHQSNINPTSKQHQTNTNNNDNKDNNEKNMNNEKK
                     KVTAFDFFQDNGFGFITPYNLDDLNYYLDSFENDSDQIVTASLKIAKDRNKVTWGYAK
                     SILNTWLNANLKSIEQVRAFEKQQLESKKQNYKPFVKQSKEKTPKWLTDSTRETKTPE
                     VDENLEKDREAFIKRLNSKWE"
     gene            7408..7626
                     /locus_tag="RPH49_001557"
     CDS             7408..7626
                     /locus_tag="RPH49_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124702.1"
                     /translation="MDAFDKYYLFDHDGNKMFSVTPHFKDERHLVVGLKHTKFNGRRW
                     YLDDYELKTLIDNEQMELGHQTSLFEYI"
     gene            7635..8039
                     /locus_tag="RPH49_001558"
     CDS             7635..8039
                     /locus_tag="RPH49_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDY5124703.1"
                     /translation="MEIEIKFNEVFNAPMGSPRPRFRNTGRYALTYMPTKYTEHKKYL
                     QNQMPKLNLENVLKIELEFYFPLLKSWSKKKKNEMVGQYKVTKPDIDNLIKTVLDACN
                     GHVWKDDNQITEITSSKRYGIEPKIIIRIEEI"
     gene            8052..8423
                     /locus_tag="RPH49_001559"
     CDS             8052..8423
                     /locus_tag="RPH49_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001651750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124704.1"
                     /translation="MARKARIVTINDKPYRFSKFEMELIESHGITAGMVSKRVKDGWE
                     LHEAMDAPEGTRLSEYREKKTIERLEQARLERKLERERKKEAELRRKKPHLFNVPQKH
                     SRDPYWFDTTYNQMFKKWQEA"
     gene            8424..8672
                     /locus_tag="RPH49_001560"
     CDS             8424..8672
                     /locus_tag="RPH49_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phi PVL orf 51-like protein"
                     /protein_id="HDY5124705.1"
                     /translation="MPKTDSACKEYLNQFFGSKRYLYQDNERVAHIHVVNGTYYFHGH
                     IVPGWQGVKKTFDTAEELETYIKQHGLEYEEQKQLTLF"
     gene            8737..9186
                     /locus_tag="RPH49_001561"
     CDS             8737..9186
                     /locus_tag="RPH49_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124706.1"
                     /translation="MMPKYRVWDEYTGRIHDVVGFDFIETEVHYENYAEAEALIHARD
                     FKDVELMQSTGLKDKNNNEIYAGDIVEFEDEILEMPDDESVIGTINRAVISIDVVNGI
                     QLKDFMFEGAVSENDYFEYIDIKSFLRYDCEVKGNIFESSHLLEVTE"
     gene            9183..9467
                     /locus_tag="RPH49_001562"
     CDS             9183..9467
                     /locus_tag="RPH49_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124707.1"
                     /translation="MNYETGVQLGVMDARLKKMRKQRDEYKKQRDELIGDIGKLRERN
                     KDLEKKASAWDRYCKSVEKDLINEFGNDDERVKFGMELNNKIFTEDDTNG"
     gene            9460..9714
                     /locus_tag="RPH49_001563"
     CDS             9460..9714
                     /locus_tag="RPH49_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1024 family protein"
                     /protein_id="HDY5124708.1"
                     /translation="MDNREQIEQSVISASAYNGNDTEGLIKEIEDVYKKAQAFDEILE
                     GMTNAIQHSVKEGIELDEAVGIMTGQVVYKYEEEQENEKI"
     gene            9834..10034
                     /locus_tag="RPH49_001564"
     CDS             9834..10034
                     /locus_tag="RPH49_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1514 family protein"
                     /protein_id="HDY5124709.1"
                     /translation="MWITMTIVFAILLLVCISINSDRAREIQALRYMNDYLLDEVVKT
                     KGYNGLEEYRIKLKRMNNDIKK"
     gene            10062..10478
                     /locus_tag="RPH49_001565"
     CDS             10062..10478
                     /locus_tag="RPH49_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDY5124710.1"
                     /translation="MIKIEKHDIKKLEEYIQHIDNYRRELKMREYELLESHEPDNAGA
                     GKSNLPGNPIERCAIKKFSDNRYNTLRNIVNGVDRLIDESDEDTLELLRFRYWDCPIG
                     CYEWEDIAHYFGTSKTSILRRRNALIDKLAKYIGYV"
     gene            10710..11009
                     /locus_tag="RPH49_001566"
     CDS             10710..11009
                     /locus_tag="RPH49_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000988331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDY5124711.1"
                     /translation="MMTKDERIRFYKSKEWQTTRKRVLERDNYECQQCKRDGKLTTYD
                     KSKHKSLDVDHILSLEHHPEFAHDLNNLETLCIKCHNKKEKRFIKKENKWKDEKW"
     gene            11140..11484
                     /locus_tag="RPH49_001567"
     CDS             11140..11484
                     /locus_tag="RPH49_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124712.1"
                     /translation="MEIIVDENLVLKEKERLQVLYKDIPSNKLKVVDGLIIQAARLRV
                     MLDYMWEDIKEKGDYDLFTQSEKAPPYERERPVAKLFNARDAAYQKIIKQLSDLLPEE
                     KEDTETPSDDYL"
     gene            11481..13142
                     /locus_tag="RPH49_001568"
     CDS             11481..13142
                     /locus_tag="RPH49_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016187779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDY5124713.1"
                     /translation="MISNKYVDEYINLWKQGKIILNKERIDLFNYLQKHIYSRDDVYF
                     DEQKIEDCIKFIEKWYFPTLPFQRFIIANIFLIDKNTDEAFFTEFAIFMGRGGGKNGL
                     ISAISDFLSTPLHGVKEYHISIVANSEDQAKTSFDEIRTVLMDNKRNKTGKTPKAPYE
                     VSKAKIINRATKSVIRYNTSNTKTKDGGREGCVIFDEIHYFFGPEMVNVKRGGLGKKK
                     NRRTFYISTDGFVREGYIDAMKHKIASVLSGKVKNSRLFAFYCKLDDPKEVDDRQTWE
                     KANPMLHKPLSEYAKTLLSTIEEEYNDLPFNRSNKPEFMTKRMNLPEVDLEKVIAPWK
                     EILATNREIPNLDNQMCIGGLDFANIRDFASVGLLFRKNDDYIWLGHSFVRQGFLDDV
                     KLEPPIKEWEKMGLLTIVDDDVIEIEYIVDWFLKAREKYGLEKVIADNYRTDIVRRAF
                     EDAGIKLEVLRNPKAIHGLLAPRIDTMFAKHNVIYGDNPLMRWFTNNVAVKVKPDGNK
                     EYIKKDENRRKTDGFMAFVHALYRADDIVDKDMSKALDALMSIDF"
     gene            13158..14345
                     /locus_tag="RPH49_001569"
     CDS             13158..14345
                     /locus_tag="RPH49_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDY5124714.1"
                     /translation="MSILEKIFKTRKDITYMLDLDMIEDLSQQAYVKRLAIDSCIEFV
                     ARAVAQSHFKVLEGNRIQKNDVYYKLNIKPNTDLSSDSFWQQVIYKLIYDNEVLIVVS
                     DSKELLIADSFYREEYALYDDIFKDVTVKDYTYQRTFTMQEVIYLKYNNNKVTHFVES
                     LFEDYGKIFGRMIGAQLKNYQIRGILKSASSAYDEKNIEKLQAFTNKLFNTFNKNQLA
                     IAPLIEGFDYEELSNGGKNSNMPFSELSELMRDAIKNVALMIGIPPGLIYGETADLEK
                     NTLVFEKFCLTPLLKKIQNELNAKLITQSMYLKDTRIEIVGVNKKDPLQYAEAIDKLV
                     SSGSFTRNEVRIMLGEEPSDNPELDEYLITKNYEKANSGENDEKEKDENTLKGGDEDE
                     SGD"
     gene            14329..15066
                     /locus_tag="RPH49_001570"
     CDS             14329..15066
                     /locus_tag="RPH49_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDY5124715.1"
                     /translation="MKAEIKGVIVSNEDKWVYEMLGMDSTCPKDVLTQLEFSDEDVDI
                     IINSNGGNLVAGSEIYTHLRAHKGKVNVRITAIAASAASLIAMAGDHIEMSPVARMMI
                     HNPSSIAQGEAKDLNHAAETLEHVGQIMAEAYAVRAGKNKQELVEMMARETWLNADEA
                     IEQGFADSKMFENDNMQIVASNTQVLSKDVLNRVTALVSKTPEVNIDIDAIANKVIEK
                     INMKEKESEIDVADSKVSANGFSRFLF"
     gene            15090..16235
                     /locus_tag="RPH49_001571"
     CDS             15090..16235
                     /locus_tag="RPH49_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001573791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDY5124716.1"
                     /translation="MTINLSETFANAKNEFINAVNNGEPQERQNELYGDMINQLFEET
                     KLQAKAEAERVSSLPKSAQSLSANQRSFFMDINKNVNYKEEKLLPEETIDRIFEDLTT
                     NHPLLADLGIKNAGLRLKFLKSETSGVAVWGKIYGEIKGQLDAAFSEETAIQNKLTAF
                     VVLPKDLNDFGPAWIERFVRVQIEEAFAVALETAFLKGTGKDQPIGLNRQVQKGVSVT
                     EGAYPEKEEQGTLTFANPRATVNELMQVFKYHSTNEKGKSVAVKGNVTMVVNPSDAFE
                     VQAQYTHLNANGVYVTALPFNLNVIESTVQEAGKVLTYVKGLYDGYLAGGINVQKFKE
                     TLALDDMDLYTAKQFAYGKAKDNKVAAVWKLDLKGHKPALEGTEETL"
     gene            16255..16539
                     /locus_tag="RPH49_001572"
     CDS             16255..16539
                     /locus_tag="RPH49_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124717.1"
                     /translation="MVKFKVVRAFKDIEHNQHKYKVGELYPAEGYNNPRVELLTNQIK
                     NKYDKVYIVPLDKLTKQELLELCESLQKKASSSMVKSEIVDLLNGEDNDD"
     gene            16529..16813
                     /locus_tag="RPH49_001573"
     CDS             16529..16813
                     /locus_tag="RPH49_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009560502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HDY5124718.1"
                     /translation="MTIDDLLVKFKSLEKIDHNSEDEYLKQLLKMSYERIKNQCGVFE
                     LENLIGQELILIRARYAYQDLLEHFNDNYRPEIIDFSLSLMEVSEDEESV"
     gene            16797..17159
                     /locus_tag="RPH49_001574"
     CDS             16797..17159
                     /locus_tag="RPH49_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HDY5124719.1"
                     /translation="MKKVFKKPRITTKRLNTRVHFYKYTENNGPEAGEKEEKLLYSCW
                     ASIDGVWLRELEQAISNGTQNDIKLYIRDPQGDYLPSEEHYLEIESRYFKNRLNIKQV
                     SPDLDNKDFIMIRGGYSS"
     gene            17156..17560
                     /locus_tag="RPH49_001575"
     CDS             17156..17560
                     /locus_tag="RPH49_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDY5124720.1"
                     /translation="MSVKVIGDKALERELEKRFGIKEMVKVQDKALIAGAKVIVEEVK
                     KQLKPSKDTGALINEVSFSKPEWINGKRTITVHWRGSKDRYKIVHLIEYGHVQKETGK
                     FIKPKAMGGVNRAIRQGQNKYFETLKRELKKL"
     gene            17557..17964
                     /locus_tag="RPH49_001576"
     CDS             17557..17964
                     /locus_tag="RPH49_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124721.1"
                     /translation="MIDILYKVHEVISQDRIIREHVNINNIKFNKYPNVKDTDVPFIV
                     IDDIDDPIPTTYTDGDECAYSYIVQIDVFVKYNDEYNARIIRNKISNRIQKLLWSELK
                     MGNVSNGKPEYIEEFKTYRSSRVYEGIFYKEEN"
     gene            17965..18609
                     /locus_tag="RPH49_001577"
     CDS             17965..18609
                     /locus_tag="RPH49_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDY5124722.1"
                     /translation="MAVKHASAPKAYINITGLGFAKLTKEGAELKYSDITKTRGLQKI
                     GVETGGELKTAYADGGPIESGNTDGEGKISLQMHAFPKEIRKIVFNEDYDEDGVYEEK
                     QGKQNNYVAVWFRQERRDGTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALF
                     PLVDNKKSVRKYIFDSANMTNHDGDGEKGEEAFLKKILGEEYTGNVTEDSEETL"
     gene            18651..18875
                     /locus_tag="RPH49_001578"
     CDS             18651..18875
                     /locus_tag="RPH49_001578"
                     /inference="COORDINATES: protein motif:HMM:NF014427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HDY5124723.1"
                     /translation="MPDSIKTLKVGDTYDLNVVVEPSNQSKLLKYTTDQTNIVSINSD
                     GQVTAEAQGIATVKATVGNMSDTITINVEA"
     gene            18925..19275
                     /locus_tag="RPH49_001579"
     CDS             18925..19275
                     /locus_tag="RPH49_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124724.1"
                     /translation="MAKLKRNIIQLVEDPKANEIKLQTYLTPHFISFEIVYEAMDLID
                     DIEDENSTMKPREIADRLMDMVVKIYDNQFTVKDLKERMHAPDGMNALREQVIFITQG
                     QQTEETRNFIQNMK"
     gene            19326..19463
                     /locus_tag="RPH49_001580"
     CDS             19326..19463
                     /locus_tag="RPH49_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124725.1"
                     /translation="MMDLIENGKDANEVLKMPFHYVLSIYQNKNNDISEEKAEALIDA
                     F"
     gene            19520..24049
                     /locus_tag="RPH49_001581"
     CDS             19520..24049
                     /locus_tag="RPH49_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001799555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDY5124726.1"
                     /translation="MGERIKGLSIGLDLDAANLNRSFAEIKRNFKTLNSDLKLTGNNF
                     KYTEKSTHSYKQRIKELDGTITGYKKNVDDLAKQYGKVSQEQGENSAEAQKLRQEYNK
                     QANELNFLEKELEKTTTEFEEFKKAQVEAQRMAESGWGKTSKVFESMGPKLTKMGDGL
                     KSIGKGLMIGVTAPVLGIAAASGKAFAEVDKGLDTVTQATGATGGELKKLQNSFKDVY
                     GNFPADAETVGGVLGEVNTRLGFTGKELESATESFLKFSHITGSEGVQAVQLITRAMG
                     DAGIEADEYQSVLDMVAKAAQASGISVDTLADSITKYGAPMRAMGFEMKESIALFSQW
                     EKSGVNTEIAFSGLKKAISNWGKAGKNPREEFKKTLAEIEKTPDIASATSLAIEAFGA
                     KAGPDLADAIKGGRFSYQEFLKTIEDSQGTVNQTFKDSESGSERFKVAMNKLKLVGAD
                     VWTSIESAFAPVMEELIKKLSIAVDWFSNLSDGSKRSIVIFGGIAAAIGPVVFGLGAF
                     ISTIGNAVTVLTPLLAGIAKADGLISFLSTKVPILGTVFTALTGPIGIVLGVLAGLAV
                     AFTIAYKKSETFRNFVNGAIESVKQTFSNFIQFIQPFIDSVKNIFKQAISAIVDFAKD
                     IWSQINGFFNENGISIVQALQNICNFIKAIFEFIINFVIKPIMFAIWQVMQFIWPAVK
                     ALIVSTWENIKGVIQGALNIILGLIKFFSSLFTGDWRGVWDAIVMILKGVVQLIWNLI
                     QLWFVGKILGVVRYFGGLLKGLIAGIWDVIKSIFSKSLSAIWNATKSIFGFLFNSVKS
                     IFTNMKNWLSNTWSSIRTNTIGKAQSLFSGVKSKFTNLWNATKEIFSNLRNWMSNIWN
                     SIKDNTVGIASRLWSKVRGIFTNMRDGLQSIISKIKSHIGGMVDAIKKGLNKLIDGLN
                     WVGGKLGMDKIPKLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGRGNGPNGFRNEMI
                     EFPNGKRVITPNTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFSLGTMWKDIKSGASSA
                     FNWTKDQIGKGTKWLGDKVGDVLDFIENPGKLLNYILEAFGIDFNSLTKGMGIAGDIT
                     KAAWSKIKKSATDWIKENLEAMGGGDLVGGILDPDKINYHYGRTAAYTAATGRPFHEG
                     VDFPFVYQEVRTPMGGRLTRMPFMSGGYGNYVKITSGVIDMLFAHLKNFSKSPPSGTM
                     VKPGDVVGLTGNTGFSTGPHLHFEMRRNGRHFNPEPYLRNAKKKGRLSIGGGDATSGS
                     GATYASRVIRQAQSILGGRYKGKWIHDQMMRVAKRESNYQSNAVNNWDINAQRGDPSR
                     GLFQIIGSTFRANAKRGYTNYNNPVHQGISAMQYIVGRYGWGGFKRAGDYAYATGGKV
                     FDGWYNLGEDGHPEWIIPTDPARRNDAMKILHYAAAEVRGKKASKNKRPSQLSDLNGF
                     DDPSLLLKMIEQQQQQIALLLKIAQSNDVIADKDYQPIIDEYAFDKKVNASIEKRERQ
                     ESTKVKFRKGGIAIQ"
     gene            24046..25530
                     /locus_tag="RPH49_001582"
     CDS             24046..25530
                     /locus_tag="RPH49_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDY5124727.1"
                     /translation="MIDTIKVNNKTIPWLYVERGFEIPSFNYVLKTENVDGRSGSIYK
                     GRRLESYSFDIPLVVRNDYLSHNGIKTHDDVLNELVKFFNYEEQVKLQFKSKDWYWNA
                     YFEGPIKLHKEFTIPVKFTIKVVLTDPYKYSVTGNKNTAISDQVSVVNSGTADTPLIV
                     EARAIKPSSYFMITKNDEDYFMVGDDEVTKEVKDYMPPVYHSEFRDFKGWTKMITEDI
                     PSNDLGGKVGGDFVISNLGEGYKATNFPDAKGWVGAGTKRGLPKAMTDFQITYKCIVE
                     QKGKGAGRTAQHIYDSDGKLLASIGYENKYHDRKIGHIVVTLYNQKGDPKKIYDYQNK
                     PIMYNLDRIVVYMRLRRVGNKFSIKTWKFDHIKDPDRRKPIDMDEKEWIDGGKFYQRP
                     ASIIAIYSAKYNGYKWMEMNGLGSFNTEILPKPKGARDVIIQKGDLVKIDMQAKSVVI
                     NEEPMLSEKSFGSNYFNVDSGYSELIIQPENVFDTTVKWQDRYL"
     gene            25546..29331
                     /locus_tag="RPH49_001583"
     CDS             25546..29331
                     /locus_tag="RPH49_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124728.1"
                     /translation="MIHVLDFNDKIIDFLSTDDPSLVRAIHKRNVNDNSEMLELLISS
                     ERAEKFRERHRVIIRDSNKQWREFIINWVQDTMDGYTEIECIASYLADITTAKPYAPG
                     KFEKKTTSEALKDVLSDTGWEVSEQTEYDGLRTTSWTSYQTRYEVLKQLCTTYKMVLD
                     FYIELSSNTVKGRYVVLKKKNSLFKGKEIEYGKDLVGLTRKIDMSEIKTALIAVGPEN
                     DKGKRLELVVTDDEAQSQFNLPMRYIWGIYEPQSDDQNMNETRLSSLAKTELNKRKSA
                     VMSYEITSTDLEVTYPHEIISIGDTVRVKHRDFNPPLYVEAEVIAEEYNIISENSTYT
                     FGQPKEFKESELREEFNKRLNIIHQKLNDNISNINTIVKDVVDGELEYFERKIHKSDT
                     PPENPVNDMLWYDTSNPDVAVLRRYWNGRWIEATPNDVEKLGGITREKALFSELNNIF
                     INLSIQHASLLSEATELLNSEYLVDNDLKADLQASLDAVIDVYNQIKNNLESMTPETA
                     TIGRLVDTKTLFLEYRKKLQDVYTDVEDVKIAISDRFKLLQSQYTDEKYKEALEIIAT
                     KFGLTVNEDLQLVGEPNVVKSAIEAARESTKEQLRDYVKTSDYKTDKDGIVERLDTAE
                     AERTTLKGEIKDKVTLNEYRNGLEEQKQYTDDQLSDLSNNPEIKASIEQANQEAQEAL
                     KSYIDAQDDLKEKESQAYADGKISEEEQRAIQDAQAKLEEAKQNAELKARNAEKKANA
                     YTDNKVKESTDAQRRTLTRYGSQIIQNGKEIKLRTTKEEFNANNRTLSNILNEIVQNV
                     TDGTTIRYDDNGVAQALNVGPRGIRLNADKIDINGNREINLLIQNMRDKVDKTDIVNS
                     LNLSREGLDINVNRIGIKGGNNNRYVQIQNDSIELGGIVQRTWRGKRSTDDIFTRLKD
                     GHLRFRNNTAGGSLYMSHFGISTYIDGEGEDGGSSGTIQWWDKTYSDSGMNGITINSY
                     GGVVALTSDNNRVVLESYASSNIKSKQAPVYLYPNTDKVPGLNRFAFTLSNADNAYSS
                     DGYIMFGSDENYDYGAGIRFSKERNKGLVQIVNGRYATGGDTTIEAGYGKFNMLKRRD
                     GNRYIHIQSTDLLSVGSDDAGDRIASNSIYRRTYSAAANLHITSAGTIGRSTSARKYK
                     LSIENQYNDRDEQLEHSKAILNLPIRTWFDKAESEILARELREDRKLSEDTYKLDRYV
                     GLIAEEVENLGLKEFVTYDDKGEIEGIAYDRLWIHLIPVIKEQQLRIKKLEESKNAG"
     gene            29321..29473
                     /locus_tag="RPH49_001584"
     CDS             29321..29473
                     /locus_tag="RPH49_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124729.1"
                     /translation="MQDNKQGLQANPEYTIHYLSQEIMRLTQENAMLKAYIQENKENQ
                     QCAEEE"
     gene            29520..>29719
                     /locus_tag="RPH49_001585"
     CDS             29520..>29719
                     /locus_tag="RPH49_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124730.1"
                     /translation="MAKEIINNTERFILVQIDKEGTERVVYQDFTGSFTTSEMVNHAQ
                     DFKSEENAKKIAETLNLLYQLT"
BASE COUNT        11472 a         4141 c         5923 g         8183 t
ORIGIN      
        1 taaacatcgg gcaacgcaga ttgtttgagt ggttacgtca aaacggattc cttattaaac
       61 gcaagggtgt ggattataac atgcctacac agtattcaat ggaacgtgag ttattcgaaa
      121 ttaaagaaac atcaatcaca cattcggacg gtcacacatc aattagtaag acgccaaaag
      181 taacaggcaa aggacaacaa tactttgtta ataagttttt aggagaaaaa caaacatctt
      241 aataggagga acgaacaatg caagctcaaa acaaaaaagt catctattac tactatgacg
      301 aagaaggtaa tagacgaccc gttaatattt aatacaacga tggctacgac ttaatgatag
      361 acccgcgttt tattgaaatg acgcttgaaa gacatccgca tttaaaaaat aacttttatg
      421 gattaataga tggaaaagaa tttaagttag attaaatttt tggaaatgca aaggaggcat
      481 aacaaatgtt acaaaaattt agaatcgcga aagaaaaaaa taaattaaaa ctcaaattac
      541 taaagcatgc tagttactgt ttagaaagaa gtaacaaccc tgaattgttg cgagcagttg
      601 cagagttgtt aaagaaggtt aactaaatta ggccttatta ttacttttta gaatgtgaac
      661 aataggtcga taaaaaactt aataaacaaa ctatagcaac tatcaatgaa ttttgaatat
      721 gtaaatcgtt ctcgtttata tagtttgtta caaagatttg aatgtcagca cctgctgcaa
      781 tgccattaga ccatcttatt aactttttga aaggatgtgg aaaatcattt tcgatacgtt
      841 tgacaaattc atcgtgtctc ttgtaggtac tttgctcatt tattggatag gtcgaattga
      901 tggcttcagc caaagtagag atagcagttg gattgatata aaaatctcta atggtctgtt
      961 gtgcttgaag tacaatctca tcatcaaacc tatagagttc cttaaaagat tttatcgttt
     1021 cttcagaaaa taaatttctt tgaaatgtta gagatgaaaa agaattacgc aaattaaaat
     1081 tcatttcaat taagttgttt agatgaaagt ctactttgaa gtcagaaaat aaatttatgt
     1141 tgtttctatt aattatatct aattggtact taggttttaa agattgttta attgccatac
     1201 ttttagaaat ttcaacatta ctaattacgt tattaataga aaaacgaaca ttttttaaag
     1261 gatcaatata caccaatatc acctcctttc actaggagat aacaacatta tacacgaaag
     1321 gaaagataga aatgccacat attttaaacg taacagttcc aatacctgaa acacatgtac
     1381 ttatcacaaa agatgaatat gatgagctaa ttggttattc attagaccct gtatggaaca
     1441 tgagtgactt aaagaagaaa ttaaaaattg catctgatga gactatcaag gacagattac
     1501 tatttcatcc tagatttgaa aaagaactaa gagcgcaagg aattgtgcat taccctgatg
     1561 agaattttaa tcgctggaga tttaacgcaa gaaagatgaa taaattcgtc gatgagcatt
     1621 tcaatgaaat atataaggag agaataaaat gagcaacatt tataaaagct acctagtagc
     1681 agtactgtgc tttacagtct tagcaattgt acttatgccg tttctatact tcactactgc
     1741 atggtcgatt gcgggattcg caagtatcgc aacattcata ttttataagg aatactttta
     1801 tgaagaataa aaaaactgtt actcacggca atgagtaaca gtctaaacaa ttagaaaatt
     1861 aatgcatatt caatataaaa cgaaataaag gaagtgtcaa caatgtacta caaaattggc
     1921 gatgtatgtc aaaaagtaat taatgtagac ggattcgatt ttaaattagc agttaagaaa
     1981 caagattaca gcattctagt gaatgtctta gatttagaag atagatttat cgacggtata
     2041 aatataacag atgagaatga tctatacaca gcattagaca tattaaatca atctatttat
     2101 gaatggattg aagagaacac agacgaaaga gacaggctaa ttaacttagt catgagatgg
     2161 taggtataag catgagagat acagaaagaa atatattgaa tatttttaag acgttattcg
     2221 acgaatatac tttgtcaaac caacgagcat tattggaaat tgaacgtaat catcacggat
     2281 acttatcgat taatttcttg cactatcacg acagttacaa aacgaacaat aagcttgtac
     2341 agatacatga aatcaatccg gacagccacg aacgaataaa aaatttaatt atcgaggtgt
     2401 taagaggtca ccgaaagatt aaaaaaggag catgaggaaa gatatgaaaa taaataagtt
     2461 aactatatcg aactttgctg gaatcaaaga agaaaaattt aactttgacg gtaaagatgc
     2521 aaaaatatac ggcaataatg cgactggcaa gactacaaca gcaaccgcat tacaatggct
     2581 gcttttcgat aaaggtttgg acggatcaac caaatcattt aaccctgtac ctttaaacga
     2641 aaaaaacgaa gaaaattatg agttaattcc gactgttttc gcagaatttg aaatcgacgg
     2701 aaaaattacg acttttaaaa aagagtcaca tcctaaatac acaataaatc aaaaaacgaa
     2761 tcgcaaggaa tactcacgaa gtcgaacgaa gaaacaatat atcaatgatg aatcaataaa
     2821 agtaaaggat tataaagctc gtattgatga actgattgat gaagatgtat tcaagttaat
     2881 tacgaaccct caagcattta acttactaga ttggaagaag cgaagaagtt tgttgtttga
     2941 aattgctaaa ccaatcaatg atgaggatgt cattaaaaca aatgatgatt ttaaagaatt
     3001 aaataatatt cttggagatc atgaaattga aacaaagaaa aagattctta cggacaagat
     3061 aaaacagatt aacaaagata tcaaagatat tccgatacgt attaaccaaa cacaacaaaa
     3121 taagcaggat gtacctgaat tcgataatga tagatacgca attatcaaac aagaaattga
     3181 gcaacttgaa aatgagcgta tagatattca aaacggtgca gaagaaatta atttgcgtaa
     3241 tcaattagct gataaacaat cagaattgaa gcgcattgaa gacaataaca gcgcaagtaa
     3301 tgagaacaaa atccatactt taacaaatga gttacacgtt gaaaatggaa cggttgcgaa
     3361 ccttaaaaca agattaaatc aaaacaaaca acaaatcgca catgaagaaa atagacgtaa
     3421 tcaattatta gaaaatcata aaggattaaa aagtgattta gaaaaagcta aaaatcaaaa
     3481 atttgaatat cttgatgaca atgtatgtag ttgttgtggt caacagttac cagctgaaca
     3541 agtgaatgag gcaagagaaa aagcattgca gaaattcaat gctagcaaat cgaaagaatt
     3601 agaaacaata caaacatcta tcaatcacat tatttcagaa ggcaagaaaa taaagccaat
     3661 catcgagaag ttagaggatg acaataataa tcttcaaatt aaaatcaacg aagcagaaga
     3721 gcgttcagca agaatacaaa acaaaattaa taagttaaaa acgactcacg ttgacgttac
     3781 acaaactgac gaatacaaag cagtaatgtt agagataaat gaaattaatc aaaaacgctc
     3841 aaacatcagg aaaactattc aagataaagt ttcaggaata gatgacaaaa taagcgaact
     3901 tactcaagaa aaatcagaaa ttgaagtgtc aagatcaatc gaaaaatcaa ataaacatct
     3961 agatgatgtt atttctgaat taagaaatga agaagataga ttattggatg aaaaagaaaa
     4021 gtattcacat gacctttata tcttaaaaga atttacaaca acaaaagtca aaatgcttac
     4081 tgaaaatatc aataatgaat ttgagattgc tgaatttaag ttattcaata ccttagttaa
     4141 cggcgaatta gaagaaacat gttccacaac ggttaacggc gtcgaatacg acagcggttt
     4201 aaataacgcc tcaagaatta atgttggctt agatatcatc aatacactgt caaaacattt
     4261 taaagttaca gcgccaatat ttattgataa tgctgaatca gtaacagagc ttatcaaaac
     4321 agaatcacaa caaattcaat tgatagtaaa tgaacaagat aaaaaattaa gaatggagac
     4381 tatataaaat gactgaaaat aataaattac aaactattga acaacaatta gtacaagaaa
     4441 agaacgtatc tgacaacgta ttaaacaaag tgagagtttt agagtcacaa ggcaatttgg
     4501 aattgccaaa tgattattca ccaagtaatg ccatgaaaca agcatggtta caaatcagcc
     4561 aagataacaa attaatgagt tgtaacgata caagcaaagc aaatgcctta ttagacatgg
     4621 taacgcaagg tttaaatcca gctaaaaatc aatgctactt tattccttac ggcaacaaaa
     4681 tgcagttaca acgtagctat cacggtaatg taatgatgtt aaaacgtgat gcaggtgctc
     4741 aagatgttgt tgctcaagtg atttataaag gcgatacatt caagcaagaa atgggagaaa
     4801 caggacgtat caaagcgatt aaacacgaac aagacttctt taacatcgac aaagaaaaca
     4861 ttatcggtgc gtactgcaca atcgtattta atgatggacg agataactat attgaagtca
     4921 tgactattga acaaattaaa caagcatgga tgcagtcatc aatgattaaa gatgaaaaag
     4981 cattacaaaa ttctaaaaca cataataatt ccaaagaaga aatggctaaa aaaacagtta
     5041 tcaatagagc tgctaaacgt tatatcaaca catcaacaga tagcaatctt ttcaaatatg
     5101 cacaagaatc cgaacaacgt caacgcaaag aagtgttaga cgcagaagtt gaagaaaatg
     5161 caaatcaaga acaattggac tttgaacaac cagttctcga agaagcacaa tacacagaat
     5221 tagaaaatga taagcctatt gatgtatctg actttgaaga aataaaagaa cctgcaacag
     5281 aaaaagaaag cgaagaagag ccattttaat tgaaacaata gcaactggtt caagtggtaa
     5341 ctgctacgtc ttaaatgatg gacgtactac gttactgctt gaggcaggaa taaaatttga
     5401 acgtgttcaa aagcatttca aatataaaac aagacatata gcagggtgtc ttatcacaca
     5461 cgaacatggt gatcatgcaa agtacacaaa gcagtttgtc gacaatggtg taatcagcta
     5521 tatgactgct ggaacacaac aagctatgaa ttttgaaagt catcgcttat gcacgattaa
     5581 ggcaaagcaa gagctgcgaa taggcacatg gtcaattcta ccgtttgaca tcgaacatga
     5641 tgctaacgag cctgtggctt tcttattaca aagtacatta ggttataagg ttctgtatgt
     5701 tactgataca aagtatttga aatacaaatt taacggcatt acgcacatga tgttagaagt
     5761 taattatatc tatgaacaaa tacaggaaaa cataaaaaac ggcagtgtgc acagcacatt
     5821 agcaaataga attatggagt ctcattttag cttagaacat gctatcggaa tgttaaaagc
     5881 aaatgattta actagactcg aagaaataca tttaattcat ttaagtagcc aaaattcaaa
     5941 tgcaaaatac attaaaagtg aaatacaaaa agtgacgggc gtgcccgttt atgttggagg
     6001 tttataaatg ataaacagaa caatattagt tggtcgttta actagagacc cagaattaag
     6061 gaccactcaa agtggtgtaa atgtagcatc attcacatta gcagttaatc gtacatttac
     6121 aaatgcacaa ggcgagcgcg aggcagactt tataaatgtc atcgtattta aaaaacaagc
     6181 agagaacgtt aataaatacc tatctaaagg atcgttgacg ggcgtagatg gtaggttaca
     6241 aacgcggaat tatgaaaata aggaaggtca acgtgtatat gttacggaag ttattgctga
     6301 tagtattcaa tttttagaac cgaaaaactc aaatgacact caacaagatt tataccaaca
     6361 acaagtacaa caaacacgtg gacaatcgca atattcaaat aacaaaccag taaaagataa
     6421 tccgtttgcg aatgcaaatg gtccgattga aatagatgac gatgatttac cattctaatt
     6481 taaccggttt gaaagtgagg tgtgtatatg actggttgga taagtattga tcgctcaatt
     6541 caaaatcatt ggctatttaa agaaaagaga acattttcaa agtttgaagc atggatatat
     6601 ttactcatgg aagcgaatca ttcaaaggca aaagtgccta ttggaaacca aattgtaacc
     6661 gtagaaagag gacaaagatt aacatcgatt ttgaccttgt ctgacctttt taactggtca
     6721 cgatttaaag tgaaaacctt ccttgactta ctcgagagtg atggaatgtt agaagtcaaa
     6781 acaacatcaa aatataccct tataaccatt gtcaattatg acttttatca aagtgagcag
     6841 ggcaggaacc aacatcaaaa cgacatcaaa ccaacatcaa aacaacatca gtcaaacatc
     6901 aacccaacat caaaacaaca tcaaaccaac acaaacaata atgataataa agataataat
     6961 gaaaagaata tgaataatga gaagaagaag gtaaccgcct tcgacttctt ccaagataac
     7021 ggattcggtt tcataactcc ttacaattta gacgatttaa attattatct tgattcattt
     7081 gaaaatgatt cagatcaaat agttaccgca tcacttaaaa tcgctaaaga tagaaacaaa
     7141 gttacttggg gatatgctaa aagcattttg aatacatggc ttaatgcaaa cttgaaatct
     7201 attgaacaag tacgtgcatt tgaaaagcaa caacttgaaa gcaaaaaaca aaattataaa
     7261 cctttcgtta aacaatcaaa agaaaaaaca cccaaatggc tcacagacag cacgagagaa
     7321 acgaaaacgc cggaagtaga tgaaaacctt gagaaagaca gagaagcttt tattaagcgt
     7381 ctaaatagca aatgggagtg attgaaaatg gatgcatttg ataaatacta tctatttgat
     7441 catgacggca acaaaatgtt ttcagttaca ccacatttta aagatgaacg gcatttagtt
     7501 gttggattaa aacatacaaa attcaatggt cgacgttggt acttagatga ttatgaatta
     7561 aaaacactta ttgataatga acaaatggag ttaggacacc aaacaagctt atttgaatat
     7621 atatgaggga ttacatggaa atagaaatta aatttaatga agtgtttaat gcgccgatgg
     7681 ggtcgcctcg tccacgcttt cgtaatacag gtagatatgc actcacatat atgcctacaa
     7741 aatatacaga acataaaaaa tatttacaaa atcaaatgcc aaagctaaat ctagaaaatg
     7801 tattaaaaat tgaattagag ttttactttc cattgcttaa atcatggtcg aagaaaaaga
     7861 aaaacgaaat ggttgggcag tataaagtga ctaagccgga tatcgacaac ttaattaaaa
     7921 cggtattaga tgcttgtaat ggccatgtat ggaaagacga taaccaaatt acagaaataa
     7981 ctagctcaaa gcgttatgga attgagccca aaataatcat acgaatagaa gaaatataag
     8041 aggtggataa aatggcgaga aaagcaagaa ttgtaacaat aaacgataaa ccttataggt
     8101 tcagtaaatt tgaaatggaa ttaatagaaa gtcacggtat aaccgctgga atggtttcta
     8161 agagagtaaa agacggttgg gaactacatg aagcaatgga cgcaccagaa ggtacgcgtt
     8221 taagcgagta cagagaaaag aaaacaatag aaagactgga acaagctaga ctcgaacgca
     8281 aattggaaag agagcgaaag aaagaggctg agctaagaag aaagaagcca catttgttta
     8341 atgtgcctca aaaacattca cgtgatccgt actggtttga tactacttat aaccaaatgt
     8401 ttaagaaatg gcaggaagca taaatgccta aaaccgatag cgcatgtaaa gaatacttaa
     8461 accaattttt cggatctaag agatatctgt atcaggataa cgaacgagtg gcacatatcc
     8521 atgtagtgaa cggcacttat tactttcatg ggcatatcgt gccaggttgg caaggcgtga
     8581 aaaagacatt tgatacagcg gaagagcttg aaacatatat aaagcaacat ggtttggaat
     8641 acgaggaaca gaagcaacta actttatttt agaggagatg aaaatgatga gaattaaaac
     8701 tgcaagcata gaggtcgaaa aagtggaggt agtagtatga tgccgaaata tcgagtgtgg
     8761 gacgaatata caggaagaat acacgatgtt gtaggattcg acttcattga gactgaagtt
     8821 cactatgaaa actacgcgga agcagaagct ttaatacatg caagagattt taaagatgta
     8881 gaacttatgc aaagtacagg acttaaagac aaaaacaaca acgaaatata tgcgggagat
     8941 atagttgagt ttgaagatga aatattagag atgccagacg atgaatctgt aataggaaca
     9001 attaatagag cagtaatatc tattgatgtt gtaaatggta ttcaattaaa agattttatg
     9061 tttgagggcg cagtctccga aaatgattac tttgagtata tagacataaa atccttcctt
     9121 agatatgact gtgaggttaa aggcaacata tttgaatcat cacatttatt ggaggtaaca
     9181 gaatgaacta tgaaacaggg gtccaactag gtgtaatgga cgctaggttg aagaagatga
     9241 gaaaacaacg tgatgagtac aagaagcaac gagatgagct tattggggat ataggtaagt
     9301 taagagaacg taacaaagat ctagagaaga aagcaagcgc atgggatagg tattgcaaga
     9361 gcgttgaaaa agatttaata aacgaattcg gcaacgatga tgaaagagtt aaatttggga
     9421 tggaattaaa caataaaatt tttacggagg atgacacaaa tggataaccg tgaacaaata
     9481 gaacaatcag tgatcagtgc tagtgcgtat aacggcaatg acacagaggg attgataaaa
     9541 gagattgagg acgtgtataa gaaagcacaa gcgtttgatg aaatacttga gggaatgaca
     9601 aatgctattc aacattcagt taaagaaggt attgaacttg atgaagcagt agggattatg
     9661 acggggcaag ttgtctataa atatgaggag gaacaggaaa atgaaaaaat ttaatgttca
     9721 aatcacatac actggcatga ttgaagagac tatcgagact gaaagtttag aagaaacaga
     9781 acttcgataa aagaaagaat tattattaat ttaaacaaga ggagatttaa atgatgtgga
     9841 ttactatgac tatcgtattt gctatattgc tattagtttg tatcagtatt aatagtgatc
     9901 gtgcaagaga gatacaagca ctcagatata tgaatgatta tctacttgat gaagtagtta
     9961 aaactaaagg atacaacggg ttagaagaat acaggattaa attaaagcga atgaataacg
    10021 atattaaaaa gtaatttata ttatcggagg tattgcattg aatgataaag attgagaaac
    10081 acgatatcaa aaagcttgaa gaatacattc agcacatcga taactatcga agagagttga
    10141 agatgcgaga atatgaatta cttgaaagtc atgaaccaga taatgcggga gctggcaaaa
    10201 gtaatttgcc gggtaatccg attgaacgat gtgcaataaa gaagtttagt gataacaggt
    10261 acaatacatt aagaaatata gttaacggtg tagatagatt gatagatgaa agtgatgagg
    10321 atacgcttga gttattaagg tttagatatt gggattgtcc tattggttgt tatgaatggg
    10381 aagatatagc acattacttt ggtacaagta agacaagtat attacgtaga aggaatgcac
    10441 tgatcgataa gttagcaaag tatattggtt atgtgtagcg gacttttacc ctatgtaagt
    10501 ccgcattaaa acagtttatt atgttagtat cagattaata tttaaagtta ttaaatgcta
    10561 atacgacgca tgaacaagag gcgcattact atgtgatgtg tctttttatt tatgaggtat
    10621 gaacatgttc aaactaattg taaatacatt actacacatc aagtatagat gcgtcttgat
    10681 actacttaag ttatataagg tgaaacatta tgatgactaa agacgaacgt atacgattct
    10741 ataagtctaa agaatggcaa acaacaagaa aaagagtact agaaagagat aattatgaat
    10801 gtcaacaatg taagagagac ggcaagttaa cgacatatga caaaagcaaa cataagtcgt
    10861 tggatgtaga tcatatatta tcgctagaac atcatccgga gtttgctcat gacttaaaca
    10921 atttagaaac actgtgtatt aaatgtcaca acaaaaaaga aaagagattt ataaaaaaag
    10981 aaaataaatg gaaagacgaa aaatggtaaa tacccccggg tcaaaaaaat caaaagcgat
    11041 caaaatactt ggggaacgag caggggctcg acttcgcgat aattttaaaa atccatgtat
    11101 aaccccccct cttataacca ttttaaggca ggtgatgaaa tggagattat agttgatgaa
    11161 aacttagtgc ttaaagaaaa agaaaggctg caagtattat ataaagacat acctagcaat
    11221 aaattaaaag tagttgatgg tttaattatt caagcagcaa ggctacgtgt aatgcttgat
    11281 tacatgtggg aagacataaa agaaaaaggt gactatgatt tatttactca atctgaaaag
    11341 gcgccaccat atgaaaggga aagaccagta gccaaactat ttaatgctag agatgctgca
    11401 tatcaaaaaa taatcaaaca attatcggat ttattgcccg aagagaaaga agacacagaa
    11461 acgccatctg atgattacct atgattagta ataaatacgt tgatgaatat ataaatttgt
    11521 ggaaacaagg aaagataatt ttaaataaag aaagaattga tctctttaat tatctacaaa
    11581 aacatatata ttcacgagat gatgtatatt ttgatgaaca gaaaatcgag gattgtatca
    11641 aatttattga aaaatggtat tttccaacat taccatttca aaggtttatc atagctaata
    11701 tatttcttat agataaaaat acagatgaag ctttctttac agaatttgct attttcatgg
    11761 gacgtggagg cgggaaaaac ggtctaataa gtgctattag tgattttctt tctacgccct
    11821 tacacggagt taaagaatat cacatctcca ttgttgctaa tagtgaagat caagcaaaaa
    11881 catcgtttga tgaaatcaga accgttttaa tggataacaa acgaaataag acgggtaaaa
    11941 cgccaaaagc tccttatgaa gttagtaaag caaaaataat aaaccgtgca actaaatcgg
    12001 ttattcgata taacacatca aacacaaaaa ccaaagacgg tggacgtgag gggtgtgtta
    12061 tttttgatga aattcattat ttctttggtc ctgaaatggt aaacgtcaaa cgtggtggat
    12121 taggtaaaaa gaaaaataga agaacgtttt atataagtac tgatggtttt gttagagagg
    12181 gttatatcga tgcaatgaag cacaaaattg caagtgtatt aagtggcaag gttaaaaata
    12241 gtagattgtt tgctttttat tgtaagttag acgatccaaa agaagttgat gacagacaga
    12301 cgtgggaaaa ggcgaaccca atgttacata aaccgttatc agaatacgct aaaacactgc
    12361 taagtacgat tgaagaagaa tataacgatt taccattcaa ccgttcaaat aagcccgaat
    12421 tcatgactaa gcgaatgaat ttgcctgaag ttgaccttga aaaagtaata gcaccatgga
    12481 aagaaatact agcgactaat agagagatac caaatttaga taatcaaatg tgtattggtg
    12541 gtttagactt tgcaaatatc cgagatttcg caagtgtagg gctactattt cgaaagaacg
    12601 acgattatat ttggttagga cattcttttg taagacaagg gtttttggat gatgtcaaat
    12661 tagagccacc tattaaagaa tgggaaaaaa tgggattatt gaccattgta gatgatgatg
    12721 tcattgaaat tgaatatata gttgattggt ttttaaaggc tagagaaaaa tatgggcttg
    12781 aaaaagtcat agctgataat tatagaactg atattgtaag acgtgcgttt gaggatgctg
    12841 gcataaaact tgaagtactt agaaatccaa aagcaataca tggattactt gcaccacgta
    12901 tcgatacaat gtttgcgaaa cataacgtaa tatatggaga caatcctttg atgcgttggt
    12961 ttactaataa tgttgcagta aaggttaaac ccgatggtaa taaagaatat attaaaaaag
    13021 atgaaaatag aagaaaaacc gatgggttca tggcttttgt tcacgcatta tatagagcag
    13081 acgatatagt agacaaagac atgtctaaag cgcttgatgc attaatgagt atagatttct
    13141 aatagaggag gtgagacatg agtattctag aaaagatatt taaaactagg aaagatataa
    13201 catatatgct tgatttagat atgatagaag atctatcaca acaagcgtat gtgaaacgtt
    13261 tagcgattga tagttgtatt gaatttgttg cgcgagctgt cgctcaaagt cattttaaag
    13321 tattggaagg taatagaatt caaaagaatg atgtttacta caagttaaat ataaaaccaa
    13381 atactgactt atcaagcgat agtttttggc aacaagttat atataaacta atttatgata
    13441 acgaggtttt aatcgtagta agtgacagca aagaattact tatcgcagat agcttttaca
    13501 gagaagagta cgctttgtat gatgatatat tcaaagatgt aacggttaaa gattatactt
    13561 atcaacgtac tttcacaatg caagaggtca tatatttaaa gtacaacaac aataaagtga
    13621 cacactttgt agaaagtcta ttcgaagatt acgggaaaat attcggaaga atgataggtg
    13681 cacaattaaa aaactatcaa ataagaggga ttttgaaatc tgcctctagc gcatatgacg
    13741 aaaagaatat agaaaaatta caagcgttca caaataaatt attcaatact tttaataaaa
    13801 atcaactagc aatcgcgcct ttgatagaag gttttgatta tgaggaatta tctaatggtg
    13861 gtaagaatag taacatgcct ttttctgaat tgagtgagct aatgagagat gcaataaaaa
    13921 atgttgcgtt gatgattggt atacctccag gtttgattta cggagaaaca gctgatttgg
    13981 aaaagaacac gcttgtattt gagaagttct gtttaacacc tttattaaaa aagattcaga
    14041 acgaattaaa cgcgaaactc ataacacaaa gcatgtattt gaaagataca agaatagaaa
    14101 ttgtcggtgt gaataaaaaa gacccacttc aatatgctga agcaattgac aaacttgtaa
    14161 gttctggttc atttacaagg aatgaggtgc ggattatgtt aggtgaagaa ccatcagaca
    14221 atcctgaatt agacgaatac ctgattacta aaaactacga aaaagctaac agtggtgaaa
    14281 atgatgaaaa agaaaaagat gaaaacactt tgaaaggtgg tgatgaagat gaaagcggag
    14341 attaaaggcg tcatcgtttc caacgaagat aaatgggttt acgaaatgct tggtatggat
    14401 tcgacttgtc ctaaagatgt tttaacacaa ctagaattta gtgatgaaga tgttgatatt
    14461 ataattaact caaatggtgg taacctagta gctggtagtg aaatatatac acatttaaga
    14521 gctcataaag gcaaagtgaa tgttcgtatc acagcaatag cagcaagtgc ggcatcgctt
    14581 atcgcaatgg ctggtgacca catcgaaatg agtccggttg ctagaatgat gattcacaat
    14641 ccttcaagta ttgcgcaagg agaagcgaaa gatctaaatc atgctgcaga aacattagaa
    14701 catgttggtc aaataatggc tgaggcatat gcggttagag ctggtaaaaa caaacaagaa
    14761 cttgtagaaa tgatggctag ggaaacgtgg ctaaatgctg atgaagccat tgaacaaggt
    14821 tttgcggata gtaaaatgtt tgaaaacgac aatatgcaaa ttgtagcaag caatacacaa
    14881 gtgttatcga aagatgtatt aaatcgtgta acagctttgg taagtaaaac gccagaggtt
    14941 aacattgata ttgacgcaat agcaaataaa gtaattgaaa aaataaatat gaaagaaaag
    15001 gaatcagaaa tcgatgttgc agatagtaaa gtatcagcaa atggattttc aagattcctt
    15061 ttttaataca aaaaatagga ggtcataaaa tgactataaa tttatcggaa acattcgcaa
    15121 atgcgaaaaa cgaatttatt aatgcagtaa acaacggtga accgcaagaa agacaaaatg
    15181 aattgtacgg tgacatgatt aaccaactat ttgaagaaac taaattacaa gcaaaagcag
    15241 aagctgaaag agtttctagt ttacctaaat cagcacaatc tttgagtgca aaccaaagaa
    15301 gtttcttcat ggatatcaat aaaaacgtta actataaaga agaaaaactt ttgccagaag
    15361 aaacaattga tagaattttt gaagatttga cgacgaatca tccgttatta gctgatttag
    15421 gtattaaaaa cgctggtttg cgtttgaagt tcttaaaatc tgaaacttct ggcgtagccg
    15481 tttggggtaa aatctatggt gaaattaaag gtcaattaga tgctgcgttc agtgaagaaa
    15541 cagcaattca aaataaattg acagcgtttg ttgttttacc aaaagattta aatgattttg
    15601 gtcctgcgtg gattgaaaga tttgttcgtg ttcaaatcga agaagcattt gcagtggcgc
    15661 ttgaaactgc gttcttaaaa ggtactggta aagaccaacc aatcggctta aaccgtcaag
    15721 tacaaaaagg tgtatcggta actgaaggtg cttatccaga gaaagaagaa caaggtacgc
    15781 ttacatttgc taatccgcgc gctacggtta atgaattgat gcaagtgttt aaataccact
    15841 caactaacga gaaaggtaaa tcagtagcgg ttaaaggtaa tgtaacaatg gttgttaatc
    15901 cgtccgatgc ttttgaggtt caagcacagt atacacattt aaatgcaaat ggcgtatatg
    15961 ttactgcttt accatttaat ttgaatgtta tcgagtctac agtccaagaa gcaggtaagg
    16021 ttttaacgta cgttaaaggt ttatatgatg gttatttagc tggtggtatt aatgttcaga
    16081 aatttaaaga aacacttgcg ttagatgata tggatttata cactgcaaaa caatttgctt
    16141 acggcaaagc gaaagataat aaagttgctg ctgtttggaa attagattta aaaggacata
    16201 agccagcttt agaaggtacc gaagaaacac tataaaattt tatgaggtga taaaatggtg
    16261 aaatttaaag ttgttagagc ttttaaagac atagagcaca atcaacacaa gtacaaagta
    16321 ggggagttgt atccagctga agggtataac aatcctcgtg ttgaattgtt gacaaatcaa
    16381 atcaaaaata agtacgacaa agtttatatc gtacctttag ataagctgac aaaacaagaa
    16441 ttattagaac tatgcgaatc attacaaaaa aaagcgtcta gttcaatggt taaaagtgaa
    16501 atcgtcgact tattgaatgg tgaagacaat gacgattgat gatttgcttg tcaaatttaa
    16561 atcacttgaa aagattgacc ataattcaga ggatgagtac ttaaagcagt tgttaaaaat
    16621 gtcgtacgag cgtataaaaa atcagtgcgg agtttttgaa ttagagaatt taataggtca
    16681 agaattgata cttatacgcg ctagatatgc ttatcaagat ttattagaac acttcaacga
    16741 taattacaga cctgaaataa tagatttttc gttatctcta atggaggtat cagaagatga
    16801 agaaagtgtt taaaaaacct agaattacaa ctaaacgttt aaatactcgt gttcattttt
    16861 ataagtatac tgaaaataat ggtccagaag ctggagaaaa agaagaaaaa ttattatata
    16921 gctgttgggc gagtattgat ggtgtctggt tacgtgaatt agaacaagct atctcaaacg
    16981 gaacccaaaa tgacattaaa ttgtatattc gtgatccgca aggtgattat ttacccagtg
    17041 aagaacatta tcttgaaatt gaatcaagat atttcaaaaa tcgtttgaat ataaagcaag
    17101 tatcaccaga tttggataat aaagacttta ttatgattcg tggaggatat agttcatgag
    17161 tgtgaaagtg ataggtgata aagcattaga aagagaatta gaaaaacgtt ttggcataaa
    17221 agagatggta aaagttcaag ataaggcgtt aatagctggt gctaaggtaa ttgttgaaga
    17281 agtaaaaaaa caactaaagc cctcaaaaga tacgggagca ttaattaatg aggtaagttt
    17341 tagtaaacct gaatggataa acggaaaacg tacaattact gttcattggc gaggttctaa
    17401 agaccgttat aaaatcgtac atttaattga atatggacac gttcaaaaag aaacaggtaa
    17461 atttatcaaa cctaaagcta tgggcggtgt taatagagca ataagacaag ggcaaaataa
    17521 gtattttgag acgctaaaaa gggagttgaa aaaattgtga ttgatatttt gtacaaagtt
    17581 catgaagtga ttagtcaaga cagaattatt agagagcacg taaatatcaa taatattaag
    17641 ttcaataaat accctaatgt aaaagatact gatgtacctt ttattgttat tgacgatatc
    17701 gacgacccaa tacctacaac ttatactgac ggagatgagt gtgcatatag ttatattgtc
    17761 caaatagatg tttttgttaa gtacaatgat gaatataatg cgagaatcat aagaaataag
    17821 atatctaatc gcattcaaaa gttattatgg tctgaactaa aaatgggaaa tgtttcaaat
    17881 ggaaaaccgg aatatataga agaatttaaa acatatagaa gctctcgcgt ttacgagggc
    17941 attttttata aggaggaaaa ttaaatggca gtaaaacatg caagtgcgcc aaaggcgtat
    18001 attaacatta ctggtttagg tttcgctaaa ttaacgaaag aaggcgcgga attaaaatat
    18061 agtgatatta caaaaacaag aggattacaa aaaattggtg ttgaaactgg tggagaacta
    18121 aaaacagctt atgctgatgg cggtccaatt gaatcaggga atacagacgg agaaggtaaa
    18181 atctcattac aaatgcatgc gttccctaaa gagattcgca aaattgtttt taatgaagat
    18241 tatgatgaag atggcgttta cgaagagaaa caaggtaaac aaaacaatta cgtagctgta
    18301 tggttcagac aagagcgtag agacggtaca tttagaacag ttttattacc taaagttatg
    18361 tttacaaatc ctaaaatcga tggagaaacg gctgagaaag attgggattt ctcaagtgaa
    18421 gaggttgaag gtgaggcact tttcccttta gttgataata aaaagtcagt acgtaagtat
    18481 atctttgatt cagctaacat gacaaatcat gatggagacg gtgaaaaagg cgaagaggct
    18541 ttcttaaaga aaattttagg cgaagaatat actggaaacg tgacagagga tagcgaagaa
    18601 actttgtaac gaaaccggct tcatcggaaa ctgcggtaaa gtcggttaat ataccagata
    18661 gcattaaaac acttaaagtt ggcgacacat acgatttaaa tgttgtagta gagccatcta
    18721 atcaaagtaa gttattgaaa tacacaacag atcaaacgaa tattgtatca atcaatagtg
    18781 atggtcaagt tactgcggaa gcacaaggca ttgctacggt taaagcaaca gttggtaata
    18841 tgagtgacac tataacaata aatgtagaag cataagaggg ggcaacccct ctattttatt
    18901 tgaaaataag gagagtatta taaaatggca aaattaaaac gtaacattat tcaattagta
    18961 gaagacccga aagcaaatga aattaaatta caaacgtact taacaccaca cttcatttca
    19021 tttgaaattg tatacgaagc aatggattta atcgatgata ttgaggacga aaatagcacg
    19081 atgaaaccaa gagaaatcgc tgacagattg atggatatgg ttgtaaaaat ttacgataac
    19141 caattcacag ttaaagacct aaaagaacgt atgcatgcac ctgatggaat gaatgcactt
    19201 cgtgaacaag taattttcat tactcaaggt cagcaaactg aggaaactag aaattttatc
    19261 cagaacatga aataaagcct gaagatttaa catataaagc aatgttgaaa aatatggata
    19321 ctctcatgat ggacttaatt gaaaatggta aagacgctaa cgaagtttta aaaatgccat
    19381 ttcattatgt actttccata tatcaaaata aaaacaatga catttctgaa gaaaaagcag
    19441 aggctttaat tgatgcgttt taaccttaac cgtttggtta gggttatttt tttgaacttt
    19501 tttagaaagg aggtaaaaaa tgggagaaag aataaaaggt ttatctatag gtttggattt
    19561 agatgcagca aatttaaata gatcatttgc agaaatcaaa cgaaacttta aaactttaaa
    19621 ttctgactta aagttaaccg gtaacaactt caaatatacc gaaaaatcaa ctcatagtta
    19681 caaacaaagg attaaagaac ttgatggaac tatcacaggt tataagaaaa acgttgatga
    19741 tttagccaag caatatggca aggtatctca agaacagggc gaaaacagcg cggaagctca
    19801 aaaattacga caagaatata acaaacaagc aaatgagctg aattttttag aaaaagaact
    19861 agaaaaaaca acaactgagt ttgaagagtt caaaaaagct caagttgaag ctcaaagaat
    19921 ggcagaaagt ggctggggaa aaaccagtaa agtttttgaa agtatgggac ctaaattaac
    19981 aaaaatgggt gatggtttaa aatccattgg taaaggtttg atgattggtg ttaccgcacc
    20041 tgttttaggt attgcagcag catcaggaaa agcttttgca gaagttgata aaggtttaga
    20101 tacagttacc caagcaacag gagcaaccgg cggagagctt aagaagttgc agaattcatt
    20161 taaagatgtt tatggcaact ttccagcaga tgctgagact gtaggcggtg ttttagggga
    20221 agttaacaca aggttaggtt tcactggcaa agaacttgag agtgccacag agtcattctt
    20281 gaaatttagt cacataacag gttctgaagg cgtacaagcc gttcaattaa ttacgcgtgc
    20341 aatgggtgat gcaggtattg aagctgatga gtatcaaagt gtacttgata tggtagcgaa
    20401 agcagcacag gctagcggta taagtgttga tacattagct gatagcatta ctaaatacgg
    20461 tgctccaatg agggctatgg gctttgagat gaaagaatca atcgctttat tctctcaatg
    20521 ggagaaatca ggtgttaata ctgaaatagc cttcagtggt ttgaaaaaag ctatatccaa
    20581 ttggggtaaa gctggtaaaa atccaagaga agaatttaag aagacattag cagaaattga
    20641 aaagacgccg gatatagcta gcgcaacaag tttagcgatt gaagcatttg gtgcaaaagc
    20701 aggtcctgat ttagcagatg ctattaaagg tggtcgtttt agttatcaag aatttttaaa
    20761 aactatcgaa gattcccaag gcacagtaaa tcaaacgttt aaagattctg aaagtggctc
    20821 cgaaagattt aaagtagcaa tgaataaatt aaaattagta ggtgctgatg tatggacttc
    20881 tattgaaagt gcgtttgcac cagtaatgga agaattaatc aaaaagctat ctatagcggt
    20941 tgattggttt tccaatttaa gtgatggttc taaaagatca attgttattt tcggtggtat
    21001 tgctgctgca attggtcctg tagtttttgg attaggcgca tttataagta caattggcaa
    21061 tgcagtaact gtattaaccc cactattagc tggtattgca aaggctgatg gattaattag
    21121 ttttttatcg actaaagtac ctatattagg aactgtcttc acggctttaa ctggtccaat
    21181 tggcattgta ttaggtgttt tggctggctt agcagtcgca tttacaattg cttataagaa
    21241 atctgaaact ttcagaaatt ttgttaatgg tgcaattgaa agtgttaaac aaacatttag
    21301 taattttatt caatttattc aacctttcat tgattctgtt aaaaacatct ttaaacaagc
    21361 gatatcagca atagttgatt ttgctaaaga tatttggagt caaattaatg gattctttaa
    21421 tgaaaacgga atttctattg ttcaagcgct tcaaaatata tgcaatttta tcaaagctat
    21481 atttgaattt attataaatt ttgtaattaa accaatcatg ttcgcgattt ggcaagtgat
    21541 gcaatttatt tggccggcgg ttaaagcttt aattgtcagt acttgggaga atataaaagg
    21601 tgtgatacaa ggagctttaa atatcatact aggtttaatt aagttcttct caagtttatt
    21661 tactggagat tggcgaggag tttgggatgc gattgttatg attcttaaag gagtcgttca
    21721 attaatatgg aatttaattc aattatggtt tgtaggcaaa atacttggcg ttgttaggta
    21781 ctttggcgga ttgctaaaag gattaatagc aggtatttgg gacgtaataa aaagtatatt
    21841 cagtaaatct ttatcagcaa tttggaatgc gacaaaaagt atttttggat tcttatttaa
    21901 tagtgtcaaa tcaattttca cgaatatgaa aaattggtta tctaatactt ggagtagtat
    21961 ccgtacgaat acgataggaa aagcgcagtc attatttagt ggcgtcaaat caaaatttac
    22021 taatttatgg aatgcgacga aagaaatttt tagtaattta agaaattgga tgtcaaatat
    22081 ttggaattcc attaaagata atacggtagg aattgctagc cgtttatgga gtaaggtacg
    22141 tggaattttt acaaatatgc gtgacggctt acaaagtatt atcagcaaaa ttaaaagtca
    22201 tatcggcggt atggtagatg ctattaaaaa aggacttaat aaattaatcg acggtttaaa
    22261 ctgggtcggt ggtaagttgg gcatggataa aatacctaag ttacatactg gtacagagca
    22321 cacacatact actacaagat tagttaagaa cggtaagatt gcacgtgaca cattcgctac
    22381 agttggagat aagggacgcg gaaatggtcc aaatggtttt agaaacgaaa tgattgaatt
    22441 ccctaatggt aaacgtgtaa tcacaccaaa tacagatact actgcttatt tacctaaagg
    22501 ctcaaaagta tataacggtg cacaaactta ttcaatgtta aacggaactc ttccaagatt
    22561 tagtttaggt actatgtgga aagatattaa gtccggtgca tcatcagcat ttaactggac
    22621 aaaagatcaa ataggtaaag gtaccaaatg gcttggcgat aaagttggcg atgttttaga
    22681 ttttattgaa aatccaggaa aacttttaaa ttatatactt gaagcttttg gaattgattt
    22741 caattcttta actaaaggaa tgggaattgc aggcgacata acaaaagctg catggtctaa
    22801 gattaagaaa agtgctactg attggataaa agaaaattta gaagctatgg gcggtggcga
    22861 tttagtcggc ggaatattag accctgacaa aattaattat cattatggac gtaccgcagc
    22921 ttataccgct gcaactggaa gaccatttca tgaaggtgtc gattttccat ttgtatatca
    22981 agaagttaga acgcctatgg gtggtagact tacaagaatg ccgtttatgt ctggtggtta
    23041 tggtaactat gtaaaaatta ctagtggcgt tatcgatatg ctatttgcgc atttgaaaaa
    23101 ctttagcaaa tcaccaccta gtggcacgat ggtaaagccc ggcgatgttg ttggtttaac
    23161 tggtaatacc ggatttagta caggaccaca cttacatttt gaaatgagga gaaacggacg
    23221 ccattttaac cctgaaccat atttaagaaa tgcaaagaaa aaaggtaggt tatcaattgg
    23281 tggcggtgat gctacttctg gaagtggtgc aacttatgcc agccgagtaa tccgacaagc
    23341 gcaaagtatt ttaggaggac gttataaagg taagtggatt catgaccaga tgatgcgagt
    23401 tgcaaagcgt gaaagcaact atcaatcaaa tgcagtgaat aattgggata ttaatgctca
    23461 aagaggagac ccgtctagag gattattcca aattatcggc tcaactttta gagctaacgc
    23521 taaacgaggg tacactaatt ataataatcc agtacatcaa ggtatctcag caatgcagta
    23581 cattgttgga cgatatggtt ggggtggttt taaacgtgct ggtgattacg catatgctac
    23641 aggtggaaaa gtttttgatg gttggtataa cttaggtgaa gacggtcatc cagaatggat
    23701 tattccaaca gatccagctc gtagaaatga tgcaatgaag attttgcatt atgcagcagc
    23761 agaagtaaga gggaaaaaag cgagtaaaaa taagcgtcct agccaattat cagacttaaa
    23821 cgggtttgat gatcctagct tattattgaa aatgattgaa caacagcaac aacaaatagc
    23881 tttattactg aaaatagcac aatctaacga tgtgattgca gataaagatt atcagccgat
    23941 tattgacgaa tacgcttttg ataaaaaggt gaacgcgtct atagaaaagc gagaaaggca
    24001 agaatcaaca aaagtaaagt ttagaaaagg aggaattgct attcaatgat agacactatt
    24061 aaagtgaaca acaaaacaat tccttggttg tatgtcgaaa gagggtttga aataccctct
    24121 tttaattatg ttttaaaaac agaaaatgta gatggacgtt cggggtctat atataaaggg
    24181 cgtaggcttg aatcttatag ttttgatata cctttggtgg tacgtaatga ctatttatct
    24241 cacaacggca ttaaaacaca tgatgacgtc ttgaatgaat tagtaaagtt ttttaactac
    24301 gaggaacaag ttaaattaca attcaaatct aaagattggt actggaacgc ttatttcgaa
    24361 ggaccaataa agctgcacaa agaatttaca atacctgtta agttcactat caaagtagta
    24421 ctaacagacc cttacaaata ttcagtaaca ggaaataaaa atactgcgat ttcagaccaa
    24481 gtttcagttg taaatagtgg gactgctgac actcctttaa ttgttgaagc ccgagcaatt
    24541 aaaccatcta gttactttat gatcactaaa aatgatgaag attattttat ggttggtgat
    24601 gatgaggtaa ccaaagaagt taaggattac atgcctcctg tttatcatag tgagtttcgt
    24661 gatttcaaag gttggactaa gatgattact gaagatattc caagtaatga tttaggtggt
    24721 aaggtcggcg gtgactttgt gatatccaat cttggcgaag gatataaagc aactaatttt
    24781 cctgatgcaa aaggttgggt tggtgctggc acgaaacgag ggctccctaa agcgatgaca
    24841 gattttcaaa ttacctataa atgtattgtt gaacaaaaag gtaaaggtgc cggaagaaca
    24901 gcacaacata tttatgatag tgatggtaag ttacttgctt ctattggtta tgaaaataaa
    24961 tatcatgata gaaaaatagg acatattgtt gttacgttgt ataaccaaaa aggagacccc
    25021 aaaaagatat acgactatca gaataaaccg ataatgtata acttggacag aatcgttgtt
    25081 tatatgcggc tcagaagagt aggtaataaa ttttctatta aaacttggaa atttgatcac
    25141 attaaagacc cagatagacg taaacctatt gatatggatg agaaagagtg gatagatggc
    25201 ggtaagtttt atcagcgtcc agcttctatc atagctatct atagtgcgaa gtataatggt
    25261 tataagtgga tggagatgaa tggattaggt tcattcaata cggagattct accaaaaccg
    25321 aaaggcgcaa gggatgtcat tatacaaaaa ggtgatttag tgaaaataga tatgcaagca
    25381 aaaagtgttg tcatcaatga ggaaccaatg ttgagcgaga aatcgtttgg aagtaattat
    25441 ttcaatgttg attctgggta cagtgaatta atcatacaac ctgaaaacgt ctttgatacg
    25501 acggttaaat ggcaagatag atatttatag aaaggagatg agagtgtgat acatgtttta
    25561 gattttaacg acaagattat agatttcctt tctactgatg acccttcctt agttagagcg
    25621 attcataaac gtaatgttaa tgacaattca gaaatgcttg aactgctcat atcatcagaa
    25681 agagctgaaa agttccgtga acgacatcgt gttattataa gggattcaaa caaacaatgg
    25741 cgtgaattta ttattaactg ggttcaagat acgatggacg gctacacaga gatagaatgt
    25801 atagcgtctt atcttgctga tataacaaca gctaaaccgt atgcaccagg aaaatttgag
    25861 aaaaagacaa cttcagaagc attgaaagat gtgttgagcg atacaggttg ggaagtttct
    25921 gaacaaaccg aatacgatgg cttacgtact acgtcatgga cttcttatca aactagatat
    25981 gaagttttaa agcaattatg tacaacctat aaaatggttt tagattttta tattgagctt
    26041 agctctaata ccgtcaaagg tagatatgta gtactcaaaa agaaaaacag cttattcaaa
    26101 ggtaaagaaa ttgaatatgg taaagattta gtcgggttaa ctaggaagat tgatatgtca
    26161 gaaatcaaaa cagcattaat tgctgtggga cctgaaaatg acaaagggaa gcgtttagag
    26221 ctagttgtga cagatgacga agcgcaaagt caattcaacc tacctatgcg ctatatttgg
    26281 gggatatatg aaccacaatc agatgatcaa aatatgaatg aaacacgatt aagttcttta
    26341 gccaaaacag agttaaataa acgtaagtcg gcagttatgt catatgagat tacttctact
    26401 gatttggaag ttacgtatcc gcacgagatt atatcaattg gcgatacagt cagagtaaaa
    26461 catagagatt ttaacccgcc attgtatgta gaggcagaag ttattgctga agaatataac
    26521 ataatttcag aaaatagcac atatacattc ggtcaaccta aagagttcaa agaatcagaa
    26581 ttacgagaag agtttaacaa gcgattgaac ataatacatc aaaagttaaa cgataatatt
    26641 agcaatatca acactatagt taaagatgtt gtagatggtg aattagaata ctttgaacgc
    26701 aaaatacaca aaagtgatac accgccagaa aatccagtca atgatatgct ttggtatgat
    26761 acaagtaacc ctgatgttgc tgtcttgcgt agatattgga atggtcgatg gattgaagca
    26821 acaccaaatg atgttgaaaa attaggtggt ataacaagag agaaagcgct attcagtgaa
    26881 ttaaacaata tttttattaa tttatctata caacacgcta gtcttttgtc agaagctaca
    26941 gaattactga atagcgagta cttagtagat aatgatttga aagcggactt acaagcaagt
    27001 ttagacgctg tgattgatgt ttataatcaa attaaaaata atttagaatc tatgacaccc
    27061 gaaactgcaa cgattggtcg gttggtagat acaaaaactt tatttcttga gtatagaaag
    27121 aaattacaag atgtttatac agatgtagaa gatgtcaaaa tcgccatttc agatagattt
    27181 aaattattac agtcacaata cactgatgaa aaatataaag aagcgttgga aataatagca
    27241 acaaaatttg gtttaacggt gaatgaagat ttgcagttag tcggagaacc taatgttgtt
    27301 aaatcagcta ttgaagcagc tagagaatcc acaaaagaac aattacgtga ctatgtaaaa
    27361 acatcggact ataaaacaga caaagacggt attgttgaac gtttagatac tgctgaagct
    27421 gagagaacga ctttaaaagg tgaaatcaaa gataaagtta cgttaaacga atatcgaaac
    27481 ggattggaag aacaaaaaca atatactgat gaccagttaa gtgatttgtc caataatcct
    27541 gagattaaag caagtattga acaagcaaat caagaagcgc aagaagcttt aaaatcatac
    27601 attgatgctc aagatgatct taaagagaag gaatcgcaag cgtatgctga tggtaaaatt
    27661 tcggaagaag agcaacgcgc tatacaagat gctcaagcta aacttgaaga ggcaaaacaa
    27721 aacgcagaac taaaggctag aaacgctgaa aagaaagcta atgcttatac agacaacaag
    27781 gtcaaagaaa gcacagatgc acagaggaga acactgactc gctatggttc tcaaattata
    27841 caaaatggta aggaaatcaa attaagaact actaaagaag agtttaatgc aaacaatcgt
    27901 acactttcaa atatattaaa cgagattgtc caaaacgtta cagatggaac aacaatcaga
    27961 tatgatgata acggagtggc tcaagcttta aatgtggggc cacgtggtat tagattaaat
    28021 gctgataaaa ttgatattaa cggtaataga gaaataaacc ttcttatcca aaatatgcga
    28081 gataaagtag ataaaaccga tattgtcaac agccttaatt tatcaagaga gggtcttgat
    28141 atcaatgtta atagaattgg aattaaaggc ggtaacaata acagatatgt tcaaatacag
    28201 aatgattcta ttgaactagg tggtattgtg caacgtactt ggagagggaa acgttcaaca
    28261 gacgatattt ttacgcgact gaaagacggt cacctaagat ttagaaataa caccgctggc
    28321 ggttcacttt atatgtcaca ttttggtatt tcgacttata ttgatggtga aggtgaagac
    28381 ggtggttcat ctggtacgat tcaatggtgg gataaaactt acagtgatag tggcatgaat
    28441 ggtataacaa tcaattccta tggtggtgtc gttgcactaa cgtcagataa taatcgggtt
    28501 gttctggagt cttacgcttc atcgaatatc aaaagcaaac aggcaccggt gtatttatat
    28561 ccaaacacag acaaagtgcc tggattaaac cgatttgcat tcacgctgtc taatgcagat
    28621 aatgcttatt cgagtgacgg ttatattatg tttggttctg atgagaacta tgattacggt
    28681 gcgggtatca ggttttctaa agaaagaaat aaaggtcttg ttcaaattgt taatggacga
    28741 tatgcaacag gtggagatac aacaatcgaa gcagggtatg gcaaatttaa tatgctgaaa
    28801 cgacgtgatg gtaataggta tattcatata cagagtacag acctactgtc tgtaggttca
    28861 gatgatgcag gagataggat agcttctaac tcaatttata gacgtactta ttcggccgca
    28921 gctaatttgc atattacttc tgctggcaca attgggcgtt cgacatcagc gcgtaaatac
    28981 aagttatcta tcgaaaatca atataacgat agagatgaac aactggaaca ttcaaaagct
    29041 attcttaact tacctattag aacgtggttt gataaagctg agtctgaaat tttagctaga
    29101 gagctgagag aagatagaaa attatcggaa gacacctata aacttgatag atacgtaggt
    29161 ttgattgctg aagaggtgga gaatttagga ttaaaagagt ttgtcacgta tgatgacaaa
    29221 ggagaaattg aaggtatagc gtatgatcgt ctatggattc atcttatccc tgttatcaaa
    29281 gaacaacaac taagaatcaa gaaattggag gagtcaaaga atgcaggata acaaacaagg
    29341 attacaagct aatcctgaat atacaattca ttatttatca caggaaatta tgaggttaac
    29401 acaagaaaac gcgatgttaa aagcgtatat acaagaaaat aaagaaaatc aacaatgtgc
    29461 tgaggaagag taatccttag cactattttt atacaaaaat ttaaggaggt catttaatta
    29521 tggcaaaaga aattatcaac aatacagaaa ggtttatttt agtacaaatc gacaaagaag
    29581 gtacagaacg tgtagtatat caagatttca caggaagttt tacaacttct gaaatggtta
    29641 accatgctca agattttaaa tctgaagaaa acgctaagaa aattgcggag acgttaaatt
    29701 tgttatatca attaactaa
//
LOCUS       DAPSKH010000035        27612 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPSKH010000035 DAPSKH010000000
VERSION     DAPSKH010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 27612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27612
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.035"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(63..1049)
                     /locus_tag="RPH49_001586"
     CDS             complement(63..1049)
                     /locus_tag="RPH49_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDY5124731.1"
                     /translation="MNDQWYKHLIGARTIKTGIAIFLTAVFCMALDLTPIYAILTAVV
                     TIEPTAKASLIKGYRRLPATVIGAGFAVLFTYLFGDQSPFTYALSATFTILFCTKLKL
                     QVGTNVAVLTSLAMIPGIHDAYIFNFLSRTLTAIIGLVTSGLINFMVFPPKYYGQVEE
                     KLSKTDALMYKLFYNRCQELILSRLQSDKSEKAYKNIFNLNNQVETLISYQRDELSYH
                     KKKECDWKLLNQLTKRAYTNRLFITHLSNIIYLPKNTRVNFSGDEKMALLKISSSIKD
                     IFYDGSFKREDDSVETLRSTIKALEISGENQIKSHILYEVLMIYRLLDSRYA"
     gene            1578..2336
                     /gene="map"
                     /locus_tag="RPH49_001587"
     CDS             1578..2336
                     /gene="map"
                     /locus_tag="RPH49_001587"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDY5124732.1"
                     /translation="MIVKTEEELQALKEIGYICAKVRNTMQAATKPGITTKELDNIAK
                     ELFEEYGAISAPIHDENFPGQTCISVNEEVAHGIPSKRVIREGDLVNIDVSALKNGYY
                     ADTGISFVVGESDDPMKQKVCDVATMAFENAIAKVKPGTKLSNIGKAVHNTARQNDLK
                     VIKNLTGHGVGLSLHEAPAHVLNYFDPKDKTLLTEGMVLAIEPFISSNASFVTEGKNE
                     WAFETSDKSFVAQIEHTVIVTKDGPILTTKIEEE"
     gene            2553..2939
                     /locus_tag="RPH49_001588"
     CDS             2553..2939
                     /locus_tag="RPH49_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124733.1"
                     /translation="MNYVERYIEQFLRATVRNNIKHYLLMLDEKMKNLDDYMRYLITK
                     KEQLSKLIDSLMLTLENKYIDIAEAFQIQCAREINNQEIENIKSELNKVEAYYAQIET
                     QIQQTSTEKIATEKTSYLINYMNAVA"
     gene            2954..3655
                     /locus_tag="RPH49_001589"
     CDS             2954..3655
                     /locus_tag="RPH49_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDY5124734.1"
                     /translation="MTHKYISTQMLIIFTALMIIANFYYIFFEKIGFLLVLLLGCVLV
                     YVGYLYFHKIRGLLAFWIGALLIAFTLLSNKYTIIILFVFLLLLIVRYLIHKFKPKKV
                     VATDEVMTSPSFIKQKWFGEQRTPVYVYKWEDVQIQHGIGDLHIDLTKAANIKENNTI
                     VVRHILGKVQVILPVNYNINLHVAAFYGSTYVNEKSYKVENNNIHIEEMMKPDNYTVN
                     IYVSTFIGDVEVIYR"
     gene            3652..4695
                     /locus_tag="RPH49_001590"
     CDS             3652..4695
                     /locus_tag="RPH49_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDY5124735.1"
                     /translation="MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIF
                     GIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKTQIERSMEGETVGINDQNIEIYS
                     ETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
                     QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLG
                     EGIKDLVIDLQKKVPMKVVHEIQDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVE
                     LFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGATFHIVSLPDSGTRIE
                     VKAPLNKEDSYDD"
     gene            4685..5314
                     /gene="vraR"
                     /locus_tag="RPH49_001591"
     CDS             4685..5314
                     /gene="vraR"
                     /locus_tag="RPH49_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator VraR"
                     /protein_id="HDY5124736.1"
                     /translation="MTIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGASGKEAIAKA
                     HELKPDLILMDLLMEDMDGVEATTQIKKDLPQIKVLMLTSFIEDKEVYRALDAGVDSY
                     ILKTTSAKDIADAVRKTSRGESVFEPEVLVKMRNRMKKRAELYEMLTEREMEILLLIA
                     KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ"
     gene            complement(5427..6644)
                     /locus_tag="RPH49_001592"
     CDS             complement(5427..6644)
                     /locus_tag="RPH49_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDY5124737.1"
                     /translation="MSKKDHSSSKYLNSVKEAQEESKKKNKSNPKIDVDRTYIEPQQF
                     QSKKPKKDDQVFFLSRLNKPAKYKKDSNFLSYLIYRIGKDDASGLAAQMTYHFVLAMF
                     PMLLFLLTLLPFFNIKQSQITNMLSNAPAETSTLIKSVIGDITQNSSGGLLSIGLILA
                     IWSASNGMTAIMNSFNVAYDVEDSRNGIVLKLLSVVFTVVMGVVFVVALALPTLGSVI
                     SHFLFGPLGFDEQVKWIFNLIRIVLPIIIIFIIFIVLYSVAPNVKTKLKSVLPGAVFT
                     SIIWLAGSFGFGWYISNFGNYSKTYGSIAGIIILLLWLYITSFIIIVGAEINAIIHQR
                     SVIKGKTPEEAALEHDDNNKNHYNENTRYEYDEDSNATHQRTYHVDEHPSDTYPEDDK
                     NIKDKIVDKLKKD"
     gene            complement(6922..7197)
                     /locus_tag="RPH49_001593"
     CDS             complement(6922..7197)
                     /locus_tag="RPH49_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDY5124738.1"
                     /translation="MENKFVPGILIGAVIGGAISLADKSTRQALVQSVKDAKNGNRTR
                     KPSKVSKIKDEVLYWKDVVEEIRRNNPELERSLKDAKETFVNRKNQR"
     gene            complement(7204..7668)
                     /locus_tag="RPH49_001594"
     CDS             complement(7204..7668)
                     /locus_tag="RPH49_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDY5124739.1"
                     /translation="MVDVAFVCLGNICRSPMAEAIMRQRLKDRNIHDIKVHSRGTGSW
                     NLGEPPHEGTQKILNKHNIPFDGMISELFEATDDFDYIVAMDQSNVDNIKSINPNLKG
                     QLFKLLEFSNMEESDVPDPYYTNNFEGVYDMVLSSCDNLIDYIVKDANLKEG"
     gene            7815..8015
                     /locus_tag="RPH49_001595"
     CDS             7815..8015
                     /locus_tag="RPH49_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1128 family protein"
                     /protein_id="HDY5124740.1"
                     /translation="MTNEEKVLAIREKLNIVNQGLLDPEKYKNANEEELTDIYDFVQS
                     RERLSPSEVTAIADALGQLRHD"
     gene            8018..9274
                     /locus_tag="RPH49_001596"
     CDS             8018..9274
                     /locus_tag="RPH49_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDY5124741.1"
                     /translation="MGILTNYKEKLQQYAELLVKVGMNVQPKQPVFIRSSVETLELTH
                     LIVEEAYHCGASDVRVVYSDPTLKRLKFENESVEHFANHELKSYDVEARMDYVKRGAA
                     NLALISEDPDLMDGIDSQKLQAFQQQNARAFKGYMESVQKNQFPWVVAAFPSKAWAKR
                     VYPELSVEEAYIKFIDEVFDIVRIDGNDPVENWRQHIANLSVYAQKLQQKNYHALHYV
                     SEGTDLTVGLAKNHIWEDATSYVNGKEQAFIANIPTEEVFTAPDRNRVDGYVTNKLPL
                     SYNGTIIDQFKLMFKDGEIIDFSAEKGETVLKDLINTDEGSRRLGEVALVPDDSPISN
                     RNTIFYNTLFDENAACHLAIGSAYAFNIQGGTEMTVEEKIASGLNDSNVHVDFMIGSS
                     DLTIYGIFEDGSKELVFENGNWASTF"
     gene            9364..9894
                     /locus_tag="RPH49_001597"
     CDS             9364..9894
                     /locus_tag="RPH49_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDY5124742.1"
                     /translation="MTNQDRPMKSMSESKCYKNRQVFPQDTNHHHTMFGGTLMANIDE
                     IAAITAMKHAGAQVVTASTDSVDFLKPIKTGDILQYVAMVSYAGTSSMEVVVQIRIDD
                     VFNNKHDLAALSYLTFVALDDEGKPKHVPGVYPEDDVEKWFYDTAPQRVERRKARRIE
                     SKQTIEYLAQVQHIRD"
     gene            complement(10154..11305)
                     /gene="yfkAB"
                     /locus_tag="RPH49_001598"
     CDS             complement(10154..11305)
                     /gene="yfkAB"
                     /locus_tag="RPH49_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM/CxCxxxxC motif protein YfkAB"
                     /protein_id="HDY5124743.1"
                     /translation="MNSVKLKQPVSIYNDPWESYNDVKEHGQLTLSNIEFTTTNLCNM
                     RCSHCAVGYTLQTVDPEPLDMDLIYRRLDEIPNLRTMSITGGEPMFSKKSIRNVVKPL
                     LKYAHHRGIYTQMNSNLTLPQDRYLDIAEYIDVMHISHNWGTTDEFANVGFGAMKKQP
                     PLKAKLKLYEQMISNARTLSEQGMFVSAETMLNQSTLPHLRKIHQEVVHDMKCSRHEI
                     HPMYPADFASQLNVLTLAEMKKTIHDILDFRDEDIWMLFGTLPVFPCLKDDEDQKLLS
                     RLRNAKNVTTRNDPDGRSRLNVNVFTGNVIVTDFGDETGTISNIQKDKLTDVFDKWLS
                     SDLAKSLNCHCSEFSCLGPNVLVKNMYYPNMDFKDNERHMHKQPQIIQF"
     gene            11529..11690
                     /locus_tag="RPH49_001599"
     CDS             11529..11690
                     /locus_tag="RPH49_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124744.1"
                     /translation="MNEQQTIEQIKARLNKFIEDIDHVNPDEVRVEDIDEWIGLLDQL
                     EEKVKLVSK"
     gene            11821..12336
                     /locus_tag="RPH49_001600"
     CDS             11821..12336
                     /locus_tag="RPH49_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDY5124745.1"
                     /translation="MTKKVAIILANEFEDIEYSSPKEALENAGFNTVVIGDTANSEVV
                     GKHGEKVTVDVGIAEAKPEDYDALLIPGGFSPDHLRGDTEGRYGTFAKYFTKNDVPTF
                     AICHGPQILIDTDDLKGRTLTAVLNVRKDLSNAGAHVVDESVVVDNNIVTSRVPDDLD
                     DFNREIVKQLQ"
     gene            12677..13486
                     /gene="sgtB"
                     /locus_tag="RPH49_001601"
     CDS             12677..13486
                     /gene="sgtB"
                     /locus_tag="RPH49_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional peptidoglycan glycosyltransferase
                     SgtB"
                     /protein_id="HDY5124746.1"
                     /translation="MKRSDRYSNSNEHFEHMKHEPHYNTYYQPVGKPPKKKKSKRILL
                     KILLTILIIIALFIGIMYFLSTRDNVDELRKIENKSSFVSADNMPEYVKGAFISMEDE
                     RFYNHHGFDLKGTTRALFSTISDRDVQGGSTITQQVVKNYFYDNDRSFTRKVKELFVA
                     HRVEKQCNKNEILSFYLNNIYFGDNQYTLEGAANHYFGTTVNKNSTTMSHITVLQSAI
                     LASKVNAPSVYNINNMSENFTQRVSTNLEKMKQQNYINETQYQQAMSQLNR"
     gene            13747..14565
                     /gene="recX"
                     /locus_tag="RPH49_001602"
     CDS             13747..14565
                     /gene="recX"
                     /locus_tag="RPH49_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDY5124747.1"
                     /translation="MPKITKIEVQKKNKERFNLFLDEQFEMGIDIDTLVKFNLKKGQQ
                     LEAADMAEIQKYDHYRIGLNKAIQYLSYKKRTEKEVIQYLQKEEISEQAISEVIEYCY
                     REKLIDHQDYAESLKNTMIRTTDKGPKIYQQKLYQLGIEPNIIEMFTELYREQQELDD
                     IIQIAEKISKTKKGPQNKVKEKVMQSLIQKGFEMETIHAVLNEMDFTQDEAVLDDLLQ
                     RDLEKIYNKNRKKYTQQKLISKTIEGLMRKGYKYDKIKAKLEESGIADGTEEIE"
     gene            14543..14857
                     /locus_tag="RPH49_001603"
     CDS             14543..14857
                     /locus_tag="RPH49_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhH family protein"
                     /protein_id="HDY5124748.1"
                     /translation="MEQKKLSEMSEPELRHEIQLYKEKMRKAEMNGILNEYDVYQSKV
                     IVAESYLVDRKKIEIGKIYKLTDGSNQYFKVERLKGIFAWGFRFNSDEPEEGLPIALL
                     QL"
     gene            14872..16389
                     /locus_tag="RPH49_001604"
     CDS             14872..16389
                     /locus_tag="RPH49_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124749.1"
                     /translation="MGSSIVLKLLKVTHYYRNKQNKKWYLPFGYDAEDIDLNNISLHI
                     YQGEALGIIGEPESSKALVGQLLAGAIKPDKGKVVCTEDLFYGYIEDQSLIHQTVEAY
                     TAQLVQLFPYEINDHKAEQIIQYAHLGDFKTKPVNHISKAAYAQLLLSIARSSKSNII
                     ILNHVIDYLTPQFMERAIELTNDYIENNLTIVSIGDDIDKISQVSNYIAWFSHGQLRM
                     EGSLKQVIPSFKEHERDRLSLNSKEEIENFDLDWKKNRTRIPEMTYNFKRVERYNHAK
                     PPKFLVRFWTLASGTILGLALMMLLIFNNIGIISITDFTNRATMQNENKDPYGEKLAY
                     GIAFNGSVDMQGDKQVTIPKYSVVTITGENSKNYRVTADNKTYYVSKDKLEYFNPAGL
                     YQTHSFKKLAPYMKSNYSNYYAYFNSQLHKKHSSVIKTLVPDDDNRFVASVTQQPIQL
                     LFNDNNQLYGFVYPIVDKKELKDKFNINNNIWITKVGNGYCIANLKEDKWIYIEL"
     gene            16398..17234
                     /locus_tag="RPH49_001605"
     CDS             16398..17234
                     /locus_tag="RPH49_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124750.1"
                     /translation="MLDNIILYFKNLPHTKRYVTERLKQSWKSFLIVLAACLILIIAS
                     ETLFSFSHLTDVKEVRWLFRIIALIVFAVVMFTIYISYHHYMNDFLVTKLFNISAATP
                     VVIMSILSFIMLVILTMISALVKPVNFETSYIALFYFIVMATIFVGLISVTFGLIRLL
                     TEKINIIFYGVCVLCILLLPIIFIPNPNHVFINHILMLNPMYYIVNGIAQSIIFGISS
                     MENIPYHFYFILFLCLIAAVNFVLARYTTHAIYNKTSKVTQTDNQQDVSNDSTDEADT
                     SS"
     gene            complement(17495..18472)
                     /locus_tag="RPH49_001606"
     CDS             complement(17495..18472)
                     /locus_tag="RPH49_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDY5124751.1"
                     /translation="MDTATHIAIGVGLTALATQDPAMASTFGATATTLIVGSLIPDGD
                     TVLKLKDNATYISHHRGITHSIPFTILWPILITFLIFTFFSGTNPFHVWMWAQLAVFL
                     HVFVDIFNSYGTQALRPITNKWIQLSVINTFDPIIFTVLCIGIVLWVIGLHPFAVFFP
                     IIALLIIYYMIRFKMRAVIKQQALKAIQQEHHPVKVFVAPTIKFMEWRVAIQTDAHDY
                     VGKAYGRNVVFSDKVERQTLSTDSILWKVKGNKDIRTFLNFSSIYRWQTTTLADGSTE
                     IRLIDLRYLKNDHYSFVAIAHVTNDNVIDHSYIGWVFTEDKLQRKLYAK"
     gene            18624..19661
                     /gene="mutY"
                     /locus_tag="RPH49_001607"
     CDS             18624..19661
                     /gene="mutY"
                     /locus_tag="RPH49_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDY5124752.1"
                     /translation="MYQQSSFKENLIHWFDENQREMPWRQTTNPYYIWLSEVMLQQTQ
                     VKTVIDYYHRFVERFPTVEVLSQASEDEVLKYWEGLGYYSRARNFHTAIKEVYDKYEG
                     LVPKDPDQFKALKGVGPYTQAAVMSIAYNVPLATVDGNVFRVWSRLNDDYRDIKLQST
                     RKSYEQELLPYVTTEAGTFNQAMMELGALICTPKNPLCLFCPVQENCEAFDKGTFEKL
                     PVKSKNVSKKVIEQSVFLIRNNQGQYLLQKRSEKLLHGMWQFPMFESEHARHEMTEKI
                     GHDIQPVETPIFELKHQFTHLTWKIKVYAVSGAINIETLPDDMIWFDLSDRDQYTFPV
                     PMSKIYQFING"
     gene            19963..20505
                     /locus_tag="RPH49_001608"
     CDS             19963..20505
                     /locus_tag="RPH49_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDY5124753.1"
                     /translation="MVRESIPKEGENIKIQSYKHDGKIHRVWSETTILKGTDHVVIGG
                     NDHTLVTESDGRTWITREPAIVYFHSEYWFNVICMFREDGIYYYCNLSSPFVCDEEAL
                     KYIDYDLDIKVYPNGKYHLLDEDEYEQHMNQMNYPHDIDIILRRNVDILQQWIEQKKG
                     PFAPDFIKVWKERYKKIRQY"
     gene            20797..22533
                     /locus_tag="RPH49_001609"
     CDS             20797..22533
                     /locus_tag="RPH49_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAV1866 family putative multidrug efflux ABC
                     transporter"
                     /protein_id="HDY5124754.1"
                     /translation="MIKRYLQFVKPYKYRIFATIIVGIIKFGIPMLIPLLIKYAIDGV
                     INNHALTTDEKVHHLTIAIGIALFIFVIVRPPIEFIRQYLAQWTSNKILYDIRKKLYN
                     HLQALSARFYANNQVGQVISRVINDVEQTKDFILTGLMNIWLDCITIIIALSIMFFLD
                     VKLTLAALFIFPFYILTVYVFFGRLRKLTRERSQALAEVQGFLHERVQGISVVKSFAI
                     EDNEAKNFDKKNTNFLTRALKHTRWNAYSFAAINTVTDIGPIIVIGVGAYLAISGSIT
                     VGTLAAFVGYLELLFGPLRRLVASFTTLTQSFASMDRVFQLIDEDYDIKNGVGAQPIE
                     IKQGRIDIDHVSFQYNDNEAPILKDINLSIEKGETVAFVGMSGGGKSTLINLIPRFYD
                     VTSGQILIDGHNIKDFLTGSLRNQIGLVQQDNILFSDTVKENILLGRPTATDEEVVEA
                     AKMANAHDFIMNLPQGYDTEVGERGVKLSGGQKQRLSIARIFLNNPPILILDEATSAL
                     DLESESIIQEALDVLSKDRTTLIVAHRLSTITHADKIVVIENGHIVETGTHRELMSKQ
                     GAYEHLYSIQNL"
     gene            22542..22634
                     /locus_tag="RPH49_001610"
     CDS             22542..22634
                     /locus_tag="RPH49_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124755.1"
                     /translation="MFDFSTILKRKFVTGWWGHNIEKAVRDFLN"
     gene            complement(22724..23818)
                     /locus_tag="RPH49_001611"
     CDS             complement(22724..23818)
                     /locus_tag="RPH49_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014667727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDY5124756.1"
                     /translation="MRLGARIFKTGIAIILAMSIASLLPDDVGLKALAGVSAVVAMQP
                     SIYRSFKTVSDQALGNIIGAILSVTMVTIFSDNFIIMGVTVIVLIAILFKFNLAHVAT
                     LASVTALIIMGQHTGSFYITAFYRFVLVMIGVISSSLVNFVFLPPKFETKIYYNSLNI
                     SSDIFMWFKLVLNDTTEFNNIKQDSHNLKQRVEKLEKIYDYYSEERPITKKHIHQQNR
                     KKILFREVVQTTRQAYEVLNKLSRYQNDLYLLNNNFLLQIKLDLDSLTAFHEQILASL
                     SKKARYNVTHVDYELDNPQKKDLLSTFQHELINHPYQTEYSFANVMQIVAAIEEYRHH
                     LEHLDRIRISFFTYHRSDADIEIVEEDFDL"
     gene            complement(24111..25400)
                     /locus_tag="RPH49_001612"
     CDS             complement(24111..25400)
                     /locus_tag="RPH49_001612"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500497.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDY5124757.1"
                     /translation="MNFSESERLQQLSNEYILGGVNSPSRSYKAVGGGAPVVMKEGHG
                     AYLYDVDGNKFIDYLQAYGPIITGHAHPHITKAIQEQAAKGVLFGTPTELEIEFSQKL
                     RDAIPSLEKIRFVNSGTEAVMTTIRVARAYTKRNKIIKFAGSYHGHSDLVLVAAGSGP
                     SQLGSPDSAGVPESVAREVITVPFNDINAYKEAIEFWGDEIAAVLVEPIVGNFGMVMP
                     QPGFLEEVNEISHNNGTLVIYDEVITAFRFHYGAAQDLLGVIPDLTAFGKIVGGGLPI
                     GGYGGRQDIMEQVAPLGPAYQAGTMAGNPLSMKAGIALLEVLEQDGVYEKLDSLGQQL
                     EEGLLKLIEKHNITATINRIYGSLTLYFTDEKVTHYDQVEHSDGEAFGKFFKLMLNQG
                     INLAPSKFEAWFLTTEHTEEDIKQTLKAADYAFSQMK"
     gene            25481..25936
                     /gene="bcp"
                     /locus_tag="RPH49_001613"
     CDS             25481..25936
                     /gene="bcp"
                     /locus_tag="RPH49_001613"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDY5124758.1"
                     /translation="MLQKGEQFPIFKLENQDGTVITNDTLKGKKAIIYFYPRDNTPTC
                     TTEACDFRDNLEMFNDLDVAVYGISGDSKKKHQNFIEKHGLNFDLLVDEDFKLAKETG
                     VYQLKKSFGKESMGIVRTTFIIDEQGKVLDVIEKVKVKTQIEELKNILG"
     gene            25942..26892
                     /locus_tag="RPH49_001614"
     CDS             25942..26892
                     /locus_tag="RPH49_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDY5124759.1"
                     /translation="MKVVGLNRMREVETELQQSFSDLDFKFYKKASEIPESDLADLDI
                     LVGYDGGINEAFLRRCPNLKWIAWFATGVNTLPLDYIADHGILVTNGKGVQAKQLSEY
                     ILAFILDDYKKMKLSYDNQRQHIYDSKITGKRLSGQTVLFLGTGAIATRTAKLAKAFN
                     MNLIGLSKSGQNKDEFDEIYTIESLESTLPNADIIINALPETQETIHLLKKKHFELMK
                     DEALFINIGRGSIVKESLLIEVLKSRVIRHAYLDVFENEPLKPNHELYELENVTITAH
                     ITGNDYEAKYDLLDIFKNNLVNFLNKNGLIENEVDAKKGY"
     gene            26989..27435
                     /gene="perR"
                     /locus_tag="RPH49_001615"
     CDS             26989..27435
                     /gene="perR"
                     /locus_tag="RPH49_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide-responsive transcriptional repressor
                     PerR"
                     /protein_id="HDY5124760.1"
                     /translation="MSVEIESIEHELEESIASLRQAGVRITPQRQAILRYLISSHTHP
                     TADEIYQALSPDFPNISVATIYNNLRVFKDIGIVKELTYGDSSSRFDFNTHNHYHIIC
                     EQCGKIVDFQYPQLNEIERLAQHMTDFDVTHHRMEIYGVCKECQDK"
BASE COUNT         9919 a         3948 c         4762 g         8983 t
ORIGIN      
        1 attttacgaa aatatcattt ctgtcccact cccatggtgc caattagcat aagatactta
       61 aattaagcat atctgctgtc tagcagtcga taaatcatta gaacttcgta tagtatatga
      121 cttttaattt gattttcacc actaatttca agtgctttta ttgtcgaacg taaagtttct
      181 acagaatcat cttctctctt aaaagaacca tcataaaata tatctttgat gctactacta
      241 atttttagca atgccatttt ttcgtcacct gaaaagttaa cacgagtatt tttaggcaag
      301 taaatgatat ttgataaatg agtgataaac aaacgattcg tatatgcacg tttagttaat
      361 tgattgagta atttccaatc acattctttt ttcttatgat agcttaattc atcacgttga
      421 taacttatta acgtttcaac ttgattgttt aaattgaaaa tatttttata tgctttttcg
      481 cttttatcag attgcagtct tgataagata agttcttggc agcgattgta aaataattta
      541 tacatcaagg catctgtctt acttaatttt tcttcgacct gaccataata cttaggtgga
      601 aacaccatga agttaattaa acctgatgtc acgagtccaa taattgctgt caatgttcga
      661 gacaaaaagt tgaatatgta ggcatcatga atacctggaa tcatagctaa tgatgttagt
      721 acagcgacat tcgtaccaac ttgcaatttg agttttgtac agaataaaat cgtgaacgtt
      781 gcactcaatg catatgtaaa aggtgattga tcgccgaata aatatgtaaa taatactgca
      841 aagcctgcac caattaccgt agcaggtaat ctacgataac ctttaataag tgatgccttg
      901 gcagttggtt caattgtgac tacagctgtt aaaatggcat agatgggtgt taaatctagt
      961 gccatacaaa agacagctgt taaaaaaatg gcaataccag ttttaattgt tctggcacca
     1021 attaaatgtt tataccattg atcgttcatt ttttaacctc taatcatcgt aaaatcttag
     1081 cgagcgcttt ataataatag tatcgtacat tggaaaagtt catgtatgta aaatatttga
     1141 aataatcata cttaagcatt actttgattt tcatatacat taatcaaagt tctgggctcc
     1201 acaatgttat attgttagta gttgactgaa ataaaatgca cttgtaacaa gcatttttca
     1261 attatagtcc ggggccccaa cacagaagct gacgaaaagt cagcttacaa taatgtgcaa
     1321 gttggggtgt gggccccaac atagagaatt tcaaaaaaga aattctacag gcaatgcaag
     1381 ttggggtgtg ggccccaaca cagagaattt cgaaaagaaa ttctacaggc aatgcaagtt
     1441 ggggacgata aagaaatatt ttttctttat cacactatgt ctcactcact ttccaaaata
     1501 ctaaagtaac atctttagta tatcaaagaa tttttgctat aataagttat aattatataa
     1561 aaaaggaacg ggataaaatg attgtaaaaa cagaagaaga attacaagcg ttaaaagaaa
     1621 ttggatacat atgcgctaaa gtgcgcaata caatgcaagc tgcaaccaaa ccaggtatca
     1681 ctacgaaaga gcttgataat attgcgaaag agttatttga agaatacggt gctatttctg
     1741 cgccaattca tgatgaaaat tttcctggtc aaacgtgtat tagtgtcaat gaagaggtgg
     1801 cacatgggat tccaagtaag cgtgtcattc gtgaaggaga tttagtaaat attgatgtat
     1861 cggctttgaa gaatggctat tatgcagata caggcatttc atttgtcgtt ggagaatcag
     1921 atgatccaat gaaacaaaaa gtatgtgacg tagcaacgat ggcatttgag aatgcaattg
     1981 caaaagtaaa accgggtact aagttaagta acattggtaa agcggtgcat aatacagcta
     2041 gacaaaatga tttgaaagtc attaaaaact taacaggtca tggtgttggt ttatcattac
     2101 atgaagcacc agcacatgta cttaattact ttgatccaaa agacaaaaca ttattaactg
     2161 aaggtatggt attagctatt gaaccgttta tctcatcaaa tgcatcattt gttacagaag
     2221 gtaaaaatga atgggctttt gaaacgagcg ataaaagttt tgttgctcaa attgagcata
     2281 cggttatcgt gactaaggat ggtccgattt taacgacaaa aattgaagaa gaatagttca
     2341 acatatacta agactaaagt atgaacatca tttagttccg gagcctattc atattggttt
     2401 cggaactgtt ttataataat taagaacaca atcaatgcgt catttcaaaa atatgttgta
     2461 ataaagtagt ttttaagcaa acatatcatc gacatcaacg aagatacata gcgcatttgg
     2521 tattttaaaa cttattataa aaggtgatag ttatgaacta tgttgaacgt tatattgaac
     2581 agtttttgag agcaacagta agaaataata tcaagcacta ccttttaatg ctagatgaaa
     2641 aaatgaaaaa tttagatgat tatatgcgtt atttaattac taaaaaagaa caacttagca
     2701 agttaattga cagtctaatg ctaacattag aaaataaata tattgatatt gctgaagcat
     2761 ttcaaattca atgtgcaaga gaaatcaata atcaagaaat tgaaaatatt aaatcagagt
     2821 tgaataaagt tgaagcatat tatgcacaaa ttgaaactca aattcaacaa acttcaactg
     2881 aaaaaatagc aacagaaaaa acatcgtatc taataaatta tatgaacgct gtggcataga
     2941 aaggcggcga aacatgacac acaaatatat atcaacgcaa atgttgatta tttttactgc
     3001 attaatgatt attgccaatt tttactacat attttttgaa aaaattggct ttttactcgt
     3061 tctattattg ggatgtgtat tagtttatgt aggatatctt tattttcata aaatacgtgg
     3121 ccttttggcg ttttggatag gcgcgctatt aattgcattc acattattgt ctaataagta
     3181 tacaatcatc atcttgttcg tctttttatt actacttatt gtgcgttatt taatacacaa
     3241 atttaaacca aaaaaagtag ttgcgacgga tgaggttatg acttcaccat cttttattaa
     3301 acaaaagtgg tttggtgagc aacgcacacc agtttatgta tataagtggg aagatgtcca
     3361 aatccaacat ggaattggcg acctacatat tgacttaaca aaagctgcaa atattaagga
     3421 aaataatacc attgttgtga gacacatttt aggtaaagta caggttatat tgccggttaa
     3481 ttacaatatt aatttacatg tagctgcttt ttatggaagt acttacgtga atgaaaaatc
     3541 atataaagtt gaaaataaca atattcatat tgaagaaatg atgaaaccgg ataactatac
     3601 agttaatatc tacgtatcaa cgtttatcgg agacgtagag gtgatttatc gatgaaccac
     3661 tacattagaa caattggttc aatgctcatc ttagtatata gcatgctagc tgcatttcta
     3721 ttcatcgata aagtttttgt aaatatcatc tattttcaag gtatgtttta tacacaaata
     3781 ttcggaatac cagtcttttt atttttaaat ctcatcatca tattattgtg tattattgtt
     3841 ggttcggtac tcgcttacaa aatcaatcag caaaatgatt ggattaagac gcaaattgag
     3901 cgttcaatgg aaggcgaaac agttggcatt aatgatcaaa atatagaaat atatagtgaa
     3961 acgttagatt tataccatac actcgtacct ttaaatcaag aattgcataa gttgcgactt
     4021 aaaactcaaa acttaaccaa tgaaaattat aatattaatg atgtgaaagt taaaaagatt
     4081 attgaagatg aacgtcaaag actagcacga gaacttcacg attctgttag tcagcaactt
     4141 tttgcggcaa gtatgatgct atctgctatc aaagaaacga agttagaacc accattagac
     4201 caacaaattc ctattttaga gaaaatggtt caagattcgc agttagaaat gcgtgctttg
     4261 ctgttacatt taagaccgct tggtttaaaa gacaaatctt taggtgaggg tattaaagat
     4321 ttagttattg atttacaaaa aaaagtgcca atgaaagttg tgcatgaaat acaagatttt
     4381 aaagtgccta aaggtattga agatcatttg ttcagaatta cacaggaagc aatttcgaat
     4441 acattgcgtc attcaaacgg tacaaaagtg acagtagaat tgtttaataa agacgattat
     4501 ttattgttga gaattcaaga taatggtaaa ggttttaatg ttgatgaaaa attagaacaa
     4561 agttatggac ttaaaaatat gcgtgaaaga gctttggaaa ttggtgcaac gttccatatt
     4621 gtatcattgc cagattcagg tacacgtatc gaggtgaaag cacctttaaa taaggaggat
     4681 tcgtatgacg attaaagtat tgtttgtgga tgatcatgaa atggtacgta taggaatttc
     4741 aagttatcta tcaacgcaaa gtgatattga agtagttggt gaaggcgctt ctggtaaaga
     4801 agcaattgcc aaagcccatg agttgaagcc agatttaatt ttaatggatt tacttatgga
     4861 agacatggat ggtgtagaag cgacgactca gattaaaaaa gatttaccgc aaattaaagt
     4921 attaatgtta actagtttta ttgaagataa agaggtatat cgtgcattag atgcaggtgt
     4981 cgatagttac attttaaaaa caacaagtgc aaaagatatc gccgatgcag ttcgtaaaac
     5041 ttctagagga gaatctgttt ttgaaccgga agttttagtg aaaatgcgta accgtatgaa
     5101 aaagcgcgca gagttatatg aaatgcttac agaacgagaa atggaaatat tattattgat
     5161 tgcgaaaggt tactcaaatc aagaaattgc tagtgcatcg catattacta ttaaaacggt
     5221 taagacacat gtgagtaaca ttttaagtaa gttagaagtg caagatagaa cacaagctgt
     5281 catctatgca ttccaacata atttaattca atagttcgta tcgaattaag aaaagttact
     5341 tacgccaatc acaatataac atcaaataga caccaaaaaa cagaggtctt cgcaatcatt
     5401 agcgaaaacc tctgttttgt tggtgtttag tcttttttaa gcttatcaac gattttgtct
     5461 tttatatttt tatcatcttc tggataggta tcactaggat gttcatcaac atgatacgta
     5521 cgttgatgtg ttgcattact atcttcatca tattcgtatc tagtgttctc attataatga
     5581 tttttattat tgtcatcatg ttctaatgct gcttcttcag gtgttttacc tttaattaca
     5641 ctacgctgat gaatgattgc attgatttca gcaccgacaa ttataataaa acttgtgata
     5701 tataaccata gtaataaaat gatgataccc gcgatactgc catatgtttt agaatagtta
     5761 ccaaaatttg aaatatacca accaaaacca aatgaaccag ctaaccaaat aattgaagta
     5821 aatactgcac ctggtaatac tgacttaagc ttcgttttaa cgttaggtgc aaccgaatat
     5881 aacacgataa atatgataaa tataataatg attggtaaca caattctaat aaggttaaaa
     5941 atccatttca cttgttcgtc aaatccaagt ggaccgaata ggaaatgact aattacagaa
     6001 ccaagcgttg gtaatgctag agcaactaca aacacaacgc ccataactac agtgaagaca
     6061 acacttagta gttttaaaac gattccatta cggctatctt ctacatcgta agcaacattg
     6121 aaagaattca taattgcagt cattccattt gaagctgacc aaattgctaa aatcaaaccg
     6181 atagataata agccaccact ggagttttga gttatatcac caattacact cttaattaga
     6241 gtagatgttt cagcgggtgc attgcttaac atattagtaa tttgactctg cttaatattg
     6301 aaaaatggta ataatgttaa taggaaaagc aacataggga acatagcaag tacgaaatgg
     6361 taagtcattt gcgctgctag tcctgaggca tcatcttttc ctatgcgata gatgagatat
     6421 gataagaaat tagagtcttt cttatatttt gcaggtttat ttaatcttga taagaagaaa
     6481 acctgatcat cttttttagg tttcttagat tggaattgtt gaggttcaat atatgtacga
     6541 tcaacatcaa ttttgggatt acttttattt ttcttttttg actcctcttg cgcttcctta
     6601 acagaattaa ggtattttga agaagagtga tcctttttcg acatgtgcac tccttaacct
     6661 ttctctatgt aatgttttat aaagtaacta ttagtattta tccaattata aaaaaactaa
     6721 acaatgatat gctttaaaaa tgataatatt atagaaatta attgatttaa atctttcata
     6781 ggctattttg atttaaaatt aaaacaaagg caatactgaa acaatgtagt ttggccaatc
     6841 attgtattat catttaataa tgataactat gaaaggcgta caccaaattg ttaagtattg
     6901 ccttataaaa acaaaatcat cttagcgttg attttttcta ttaacaaatg tttctttcgc
     6961 atcctttaat gaacgttcta attcaggatt attacgacga atttcttcaa caacatcttt
     7021 ccagtataaa acttcgtctt taatcttgct gactttagaa ggcttacgag tgcggttacc
     7081 attttttgca tctttaactg attgaactaa agcttgacgt gtagatttat cagctaaact
     7141 aattgcacca ccaattacgg caccaattaa aataccagga acaaatttat tttccataaa
     7201 aaactacccc tctttcaaat ttgcatcttt tacgatgtag tctattaaat tatcacaaga
     7261 tgataatacc atgtcgtata caccttcaaa attattcgtg tagtatggat ctggtacatc
     7321 actctcttcc atattactaa attctaacag tttgaacaat tgtcccttaa gattaggatt
     7381 gatagattta atattatcaa cgttactttg atccatagcc acaatgtaat caaaatcatc
     7441 tgtcgcttcg aataattcac taatcatgcc atcaaatgga atattgtgtt tgttgagaat
     7501 tttttgtgta ccttcatgag gcggctctcc taaattccag ctaccagtac ctcttgaatg
     7561 tactttaata tcatgaatat ttctgtcttt aagtctttgt cgcatgattg cttctgccat
     7621 tggagaacga catatattgc caagacagac aaatgctaca tctaccattt tgattcctcc
     7681 aaactatgta gttatatccc cattttatag cgactttaaa caataagaaa gcagattata
     7741 taaaattcta ttaaagttta ttaaattgtg atactttgat aacataacta ttattagagg
     7801 tgaacattgt ggctatgaca aatgaagaga aagtattagc tattagagag aagttaaata
     7861 ttgttaatca aggattatta gatcctgaaa aatataaaaa tgcaaatgaa gaagaattaa
     7921 cagatatata tgattttgtt caatcaagag aaagattgtc gccaagtgaa gtgacagcta
     7981 ttgctgacgc tttaggacaa ttgcgacacg actaggagtg ggaattttga ctaattacaa
     8041 agaaaagtta caacaatacg ctgaactatt agttaaggtt ggtatgaatg ttcaaccaaa
     8101 acagccagta tttattagat catcagtaga aacattagaa ttaacgcatt taattgtaga
     8161 agaagcatat cattgtggcg cttcagatgt acgtgttgta tatagcgatc caaccttaaa
     8221 acgcttaaaa tttgaaaatg aatctgtgga acattttgct aatcatgagt taaaatcata
     8281 tgatgttgaa gcgagaatgg attacgttaa acgtggcgct gctaatttag cacttattag
     8341 tgaagatcct gatttaatgg atggtatcga tagccaaaaa ttacaagcat ttcaacaaca
     8401 aaacgcacgc gcatttaaag gatatatgga aagtgtacaa aaaaatcaat ttccatgggt
     8461 cgtagctgct tttccatcta aagcttgggc gaagagagtg tatcctgaac tatctgtaga
     8521 agaagcatat attaagttta ttgacgaggt attcgatatt gtgcgaattg atggtaacga
     8581 tccagttgaa aattggcgtc aacacatcgc taatttaagt gtttacgctc aaaagttaca
     8641 acaaaaaaat taccatgcgt tgcattatgt atctgaaggt actgatttaa cggtaggttt
     8701 agcgaaaaat catatctggg aagatgctac aagttatgtt aacggcaagg aacaagcttt
     8761 tattgctaat ataccaactg aagaagtatt tacagcacca gatcgaaata gagtagatgg
     8821 atatgttact aataaattgc ctttaagtta taatggcaca attatcgatc aatttaaatt
     8881 gatgtttaaa gatggagaga ttattgattt ttcagctgaa aaaggtgaaa cggtattgaa
     8941 agatttaatc aatactgatg aaggttcaag aagattaggt gaagtagcat tagtacctga
     9001 tgattcaccg atatcaaatc gtaataccat tttttacaat actttatttg atgaaaatgc
     9061 agcatgtcat ttagcgattg gatctgctta cgcctttaat attcaaggtg gaacggaaat
     9121 gactgttgag gaaaagattg caagcggatt aaatgattca aatgtacatg tcgatttcat
     9181 gattggtagt agtgatttga ctatttatgg catattcgaa gatggttcaa aagaactagt
     9241 atttgaaaat ggaaattggg catcaacatt ttaataaatg ttattttgag gtgctgagta
     9301 ggaaatgaaa catgtattta aaggtcaaat acgtgattaa agtatagatt gggagataaa
     9361 ataatgacaa atcaggacag accaatgaaa tctatgtcag aatcaaaatg ttataaaaat
     9421 agacaagttt tccctcaaga tacgaatcac catcatacaa tgtttggtgg tacattgatg
     9481 gctaatattg atgaaattgc agcaatcaca gctatgaaac atgctggtgc gcaagtagtt
     9541 accgcatcta cagactcagt agatttctta aagccgatta aaacagggga catattacaa
     9601 tacgtagcga tggtttcata cgctgggact agttcaatgg aagtggtcgt tcaaattaga
     9661 attgacgatg tatttaataa caagcatgat ttagctgcat taagttactt aacatttgtt
     9721 gcgttagatg atgaaggcaa acctaaacat gtacctggtg tatatccaga agatgatgtt
     9781 gaaaaatggt tttatgatac agcaccacaa cgtgttgaac gaagaaaagc acgtcgcatt
     9841 gaaagtaaac aaacaattga atatttagct caagtgcaac atattagaga ctaaaaatat
     9901 aaagacagat tgttaaggat gaattgaact gttatgttcg aatattccac ctacaatctg
     9961 tctttttgat tatgcacgtt tatgctttta gttaaaattt acccctttta ttatagacta
    10021 ttagtcctat taaatgacct ttattattaa agtagagtac tgccagcaat taattgtttt
    10081 ttattttata atagcattaa aatatgcgga gactacttat cgataaagtg cttctccgca
    10141 taattaagcg tttttaaaat tgtataattt gtggttgttt gtgcatatga cgctcattat
    10201 ctttaaaatc catattcgga tagtacatat ttttaacaag aacatttggt cctaaacaac
    10261 taaactcgga acaatgacaa tttaatgatt tagcaagatc agaggataac catttatcaa
    10321 atacatctgt taatttatct ttttgtatat tcgaaattgt acctgtttca tctccgaaat
    10381 cagttacgat tacattacct gtaaatacat tgacatttaa acgactacgg ccatccgggt
    10441 catttctagt cgttacattt ttagcatttc ttaaacgtga tagtaacttt tgatcttcat
    10501 catcctttaa gcatggaaac acaggcaaag taccaaataa catccaaata tcttcatctc
    10561 tgaaatccaa tatatcatga attgtctttt tcatttccgc tagagttaac acatttaatt
    10621 gacttgcaaa gtcagctgga tacatagggt gaatctcgtg tctgctacat ttcatatcat
    10681 gaacgacttc ttgatgtatt tttcgtaaat gtggtagcgt actttgattg agcattgttt
    10741 ccgcagatac aaacattcct tgttctgata atgtacgtgc attcgaaatc atttgttcat
    10801 ataattttaa cttagctttt aacggtggtt gcttcttcat tgcgccaaag ccaacatttg
    10861 cgaattcatc agttgttccc cagttatgtg agatatgcat aacatcgata tattcagcaa
    10921 tatctaaata acgatcttga ggcaatgtta ggtttgaatt catttgtgta tatatacctc
    10981 gatgatgtgc atactttaat agaggtttaa caacatttct aatagacttt ttagaaaaca
    11041 ttggttcgcc acctgtaatt gacatcgttc gcagatttgg aatttcatca agtctacgat
    11101 aaattaagtc catatctaaa ggctcggggt cgacagtttg taaagtataa ccaactgcac
    11161 agtggctaca acgcatatta caaagatttg tagttgtaaa ttcgatgtta cttaaagtta
    11221 attggccatg ttctttaaca tcgttatatg attcccatgg atcattgtaa atgctaacag
    11281 gttgcttcaa tttgacgcta ttcatcgtct taaacttcct tctttctatt tggttcatat
    11341 cggtatgata ccacttcgta ttatcactcg taacaaatta tctcttaatt ttagttaatt
    11401 gaaaagggga tttttaaaag tcaaaataat ttgaatgtca taaatatagc taagattata
    11461 tcgctttaac gcaatttctg ttaggataat aatgaaaaag aaaacaaaat aaaaggagtt
    11521 aactttttat gaatgaacag caaacaatcg aacagataaa agcgcgttta aataagttta
    11581 ttgaggatat cgatcatgta aatcctgatg aagtacgtgt tgaagatata gatgaatgga
    11641 ttggattgtt agatcagctt gaagaaaagg ttaaattagt atctaagtaa atgccacata
    11701 agatgtgtta gggttagata tcgcgacagt cgcttaataa tttttatatc ttgtatgttt
    11761 aatcactgat ttacttgtct atagtaatta tatcaatgat atatagaaag gtgattttca
    11821 atgactaaaa aagtagcaat tattctagca aacgaatttg aagatataga atattcaagc
    11881 cctaaagagg cattagagaa tgcaggcttt aatactgtag tgattggaga tactgcaaat
    11941 agtgaagttg ttggtaaaca cggtgaaaaa gttactgtcg atgtaggcat tgcagaagct
    12001 aaaccagaag attatgatgc attattaatt cctggaggat tttcaccaga tcatttacgt
    12061 ggagatacag aaggtcgata tggcacattt gctaaatact ttactaaaaa tgatgtacca
    12121 acatttgcca tttgtcatgg gccacaaata ctaatagata cagacgattt aaaaggtcgt
    12181 acgttaacag cagtattaaa tgtacgcaaa gatttatcaa atgcaggcgc acatgtagtt
    12241 gatgagtcag tagttgtaga caacaatatt gtaacaagtc gagtaccaga cgatttagat
    12301 gattttaatc gagaaatcgt taaacaatta caatagaagt attgtggtta tcgattgtta
    12361 aaatttatat attttcgttt gaaatgaaat atggatttta gttttaataa atgaataaca
    12421 aataaaaggt cgtctctatt ggcatttaat agggatggtc ttttattttt acaaaatata
    12481 acaatatttg acatgattaa tatttaaaat tgcaatgatt tatctataat tttttcaaaa
    12541 aacaaaaaag taagtatgat ggcgtatacg attgtaagcc cttggactga ttttcccaaa
    12601 aagtgtagcc tatttgtgat agtactggta aactcaaggt atatactaag tgagttttaa
    12661 aagaaggagc aaacgcatga aaagaagcga taggtactca aactcaaatg aacattttga
    12721 gcatatgaaa cacgaacctc actataatac gtattatcaa ccagttggca aaccgccgaa
    12781 aaagaaaaaa agtaaacgaa tactattgaa aatattatta accattctaa tcattatcgc
    12841 attgtttatt ggtatcatgt attttttatc tacacgcgat aatgtggatg aactaagaaa
    12901 aattgaaaat aaaagtagtt ttgtgtcagc tgataacatg ccagagtatg ttaaaggtgc
    12961 ctttatttca atggaagatg aacgattcta caatcatcat ggattcgatt tgaaaggtac
    13021 aactagagct ttattttcaa cgattagcga cagagatgtg caaggtggta gtaccattac
    13081 acaacaagtt gtcaaaaatt atttttatga taatgatcgt tcatttacta gaaaagtaaa
    13141 agaattattt gtagctcatc gagttgaaaa acaatgtaat aagaacgaaa ttttaagctt
    13201 ttatttaaat aatatttact ttggggataa tcaatatacg cttgagggcg cagcaaacca
    13261 ttactttgga acaaccgtga ataaaaatag tacaacaatg tctcacataa cagttttaca
    13321 aagcgctatt ttagctagta aagtcaatgc acctagcgta tataatatca ataatatgtc
    13381 agagaatttt acgcaacgtg taagcacgaa cttagaaaaa atgaagcaac aaaattatat
    13441 caatgaaaca caatatcaac aggctatgtc acaattaaat cgttaaatac ttgcattcat
    13501 gtgtaagatg cttggaacta taatgtagaa ggtttaattg aaatgtcata atgataaagt
    13561 tgaattgttt ctgctttata aattttacag atttgcttgt aatcacactt tcattttaaa
    13621 agatgatagt gtgatttttt gttagcatcg aaaaatattt aaagttaaac atttgctata
    13681 ggaagtggct tattgaataa taaaagagta ttgtattaaa acttgagaaa gtaacggggt
    13741 gatccagtgc cgaagattac taaaatagaa gttcaaaaga aaaacaaaga acgttttaat
    13801 ctttttttag acgaacaatt tgaaatgggt atagatatcg atacattagt caaatttaat
    13861 ttaaaaaaag ggcaacaact tgaagctgct gacatggcag agattcaaaa gtatgatcat
    13921 tatcgcatag gtttaaacaa agcaatccaa tatttatcat ataaaaagag aactgaaaaa
    13981 gaagttatac aatatttaca aaaagaagag atatcagagc aagcgatttc tgaagtgatt
    14041 gaatattgtt atcgcgaaaa gttaatcgac catcaagatt atgcggaaag tttaaaaaat
    14101 acaatgattc gcacgacaga taaaggacct aaaatttatc aacaaaaact atatcaactt
    14161 ggtatagaac caaatatcat tgaaatgttt acagaacttt atagagaaca acaggaactt
    14221 gatgatatta tccaaattgc tgaaaaaata tctaaaacaa aaaaagggcc acaaaataag
    14281 gttaaagaaa aagtaatgca atctttaatt caaaaagggt ttgaaatgga aaccattcat
    14341 gctgtattga atgaaatgga ttttacacaa gatgaagcgg ttttagacga tttattacaa
    14401 cgagatttag aaaaaattta taataaaaat cgaaagaagt acacgcaaca gaaattaatt
    14461 tcaaaaacta tcgaaggcct tatgagaaaa ggatataaat atgataaaat taaagctaaa
    14521 ttagaagaaa gtggtattgc cgatggaaca gaagaaattg agtgagatgt ctgagccaga
    14581 attaagacac gaaatacaac tttataaaga gaaaatgaga aaagctgaga tgaacggtat
    14641 tttaaatgaa tatgacgttt atcaaagtaa agtaattgtt gccgaaagtt acttagtaga
    14701 cagaaaaaag atagaaattg gtaaaattta taaactgact gatggcagta atcaatattt
    14761 taaagtagaa agattaaaag gtatttttgc gtgggggttt agatttaata gcgatgaacc
    14821 cgaagaaggc ttacctatag cgttattaca attatagaag gatgaaaata gatgggaagt
    14881 tcaattgttt taaagttact aaaagtaaca cactactata ggaataaaca gaataaaaaa
    14941 tggtatttac cttttggata tgatgctgaa gatatcgatt taaacaatat tagtttacat
    15001 atttatcaag gagaagcatt aggtataatt ggtgaacctg aatcttccaa agcgttggta
    15061 ggtcaattgt tggcaggtgc aattaaacct gataaaggta aagtagtttg tactgaagat
    15121 ttgttctacg gatatattga agatcaatcg ttaattcatc aaactgttga agcttataca
    15181 gcgcagttag ttcaactatt tccatatgaa attaatgatc ataaagctga acagattatt
    15241 caatatgcac atttaggcga ttttaaaacg aagccggtta accatatatc gaaagcggca
    15301 tacgctcaat tactattaag tattgcacgc tcatcaaaat caaatattat tattttaaat
    15361 catgttattg actatttaac accacaattt atggaacgtg cgattgaatt aacaaatgat
    15421 tatattgaaa ataatttaac gattgtgtca attggtgatg atattgataa aatttcacaa
    15481 gtgagtaact acatagcttg gttttcacat ggtcaattaa gaatggaagg gtcacttaaa
    15541 caagttattc catcttttaa agaacatgaa cgtgatcgat taagtctaaa ctcaaaagaa
    15601 gaaattgaaa actttgattt agattggaaa aagaatcgta caagaatacc agagatgacc
    15661 tataatttca aacgtgttga gcgctataat catgcaaaac cgcctaagtt tttagtgcgt
    15721 ttttggactt tagcctcagg taccatttta ggcttagcat tgatgatgtt gctcattttc
    15781 aataatatag gaattatttc gataacagat tttacgaatc gtgctacgat gcaaaatgaa
    15841 aataaagatc catatggcga aaagttagct tatggaattg cttttaatgg cagtgtggat
    15901 atgcaagggg ataaacaagt cacaattcca aaatatagtg tagttacaat tactggcgaa
    15961 aatagtaaaa attatcgtgt taccgccgat aataagactt actatgttag taaagataaa
    16021 ttagaatatt ttaacccggc aggtttatat caaacgcata gttttaaaaa attagcacca
    16081 tatatgaaat caaattatag taattactat gcatacttta atagtcaatt acataaaaag
    16141 catagttcag ttattaaaac tttagttcct gatgatgata accgtttcgt tgcatccgtt
    16201 acacaacaac cgatacaatt acttttcaat gataataatc agttatatgg ttttgtttat
    16261 ccaattgtag ataaaaaaga attaaaagat aagtttaata ttaacaataa catttggatt
    16321 actaaagttg ggaatggata ttgtattgcc aatttgaaag aagacaaatg gatttatatt
    16381 gaattgtagg tgtaaagatg ctagataata ttattttata ttttaaaaac ttaccgcata
    16441 ctaaaaggta tgtaacagaa cgtttaaaac aaagttggaa aagttttcta atcgtattag
    16501 ctgcatgttt aatacttatt attgcaagtg aaacgctatt ttcctttagt catttgaccg
    16561 atgttaaaga ggtgcgatgg ttatttagaa ttattgcatt gattgttttt gcggtagtga
    16621 tgttcacaat ttatatctct tatcatcatt atatgaatga ctttttagtt actaagttat
    16681 ttaatatttc cgcagcgacg ccagtagtta ttatgtctat tttaagtttt attatgctag
    16741 tcattttgac gatgattagt gcattggtta aaccagtaaa cttcgaaaca tcatatatag
    16801 cgctattcta ttttattgtg atggcaacta tttttgtagg attaatatcc gttacttttg
    16861 gtcttattcg actgttaact gaaaaaataa atatcatatt ttatggggtt tgtgtattgt
    16921 gtatcttatt gttaccaatt attttcatac caaatccaaa tcatgtattt atcaatcaca
    16981 tcctaatgct gaatccaatg tattacattg ttaatggtat agcacaatct atcatatttg
    17041 gtatatcaag tatggaaaac attccatatc atttttactt tattttattc ttatgtttaa
    17101 tagctgcagt aaatttcgta ttagcaaggt atacgacaca cgcaatttat aataaaacat
    17161 ctaaagtgac acaaactgat aatcaacagg atgtttcaaa tgatagtaca gacgaggcgg
    17221 atacttcttc atgatgttta gctgacctgt tgtgtaaatt aatctgtgag aatcagaaac
    17281 aattagaata tcatctagat attgttttcc tatactgatt ttgatatttc gagtcattaa
    17341 aggtagtttg ttagcaacaa tataaatttt agattttgta aaagcattca tagttttaca
    17401 ttaaaaaacc ggacagagta aaaatcgttt tgattttcat tctgcccggt tgttcatttt
    17461 ttatagatta actttagtga ataataactt gaaattattt agcatacagt ttacgttgta
    17521 acttatcttc tgtaaatacc cagccaatat aagagtggtc tatgacatta tcgtttgtta
    17581 catgtgcaat tgccacaaat gaataatgat cattttttaa ataacgcaaa tcaatcaaac
    17641 gaatttcagt agaaccatct gctaacgttg ttgtttgcca acgatagatt gatgaaaagt
    17701 ttaaaaaagt acgtatatct ttattacctt tgactttcca taaaatggag tctgttgata
    17761 atgtttgacg ttccacttta tcactaaaca ccacattcct accatatgct tttccaacat
    17821 agtcatgtgc atcagtttgt atcgcgacac gccattccat aaattttatt gttggcgcaa
    17881 caaatacttt aacagggtga tgctcttgtt gaattgcttt taaagcttgt tgcttaatta
    17941 cggctctcat tttaaaacga atcatgtaat aaatgattag taaagcgatt ataggaaaga
    18001 agactgcaaa tggatgcaag cctataaccc ataatacaat accaatacaa agaactgtga
    18061 aaataatagg gtcaaatgtg ttaatcacac ttaattgaat ccatttgttt gtgataggtc
    18121 taagtgcttg tgtaccataa gaattgaata tatctacaaa gacatgtaaa aatactgcga
    18181 gctgagccca catccataca tgaaatgggt tggttccact aaagaacgtg aatattaaaa
    18241 atgtaattaa aattggccat agtattgtga aagggatgga atgcgtgata cctctatgat
    18301 gcgaaatata tgttgcattg tcctttaatt taagaacagt atccccatca ggaattaatg
    18361 aaccaacgat aagggttgta gctgttgcac caaacgtaga agccattgct ggatcttgag
    18421 ttgcaagtgc tgtaaggccc accccaattg cgatatgtgt tgcagtgtcc atatcagttc
    18481 actcatttca taatattata tatactatta taatccaatt tcgcaaataa ctaaattaac
    18541 ttacatacta accatgattt taatgtacaa taaaaacatt atgagtaaag acaattaatt
    18601 ttggtgagga aagggtttta taaatgtatc agcagtctag ttttaaagaa aatttgatac
    18661 actggtttga tgaaaatcaa agagaaatgc catggcgaca aacgaccaat ccgtactata
    18721 tttggttaag tgaggtcatg ttacaacaga cacaagttaa aacagttatt gactattatc
    18781 atcgttttgt tgaacgattt ccaactgtgg aagttttgag tcaagcttcg gaagatgaag
    18841 tgttaaagta ttgggaaggc ttaggatatt atagtagagc tcgaaatttt catacggcga
    18901 ttaaagaagt ttatgataaa tatgaaggct tagttcccaa agatcctgat caatttaaag
    18961 cgttaaaagg tgttggccca tacacacaag ctgcagtaat gagcattgca tataatgtac
    19021 cactagcaac tgtagacgga aatgtttttc gagtatggtc tagattgaat gatgactatc
    19081 gagatattaa attacaatcg acgaggaaat cgtacgaaca agaattgtta ccgtatgtta
    19141 ctacagaagc tggaacgttt aatcaagcta tgatggaatt aggggcatta atttgtacac
    19201 caaaaaatcc attatgctta ttttgtccag ttcaagaaaa ctgtgaggca tttgataaag
    19261 gtacatttga aaagttacct gttaaatcta aaaatgtaag taaaaaagta attgagcaat
    19321 ccgtcttttt aattagaaat aatcaaggtc aatatctgtt gcaaaagcgt agcgaaaaat
    19381 tattgcatgg tatgtggcaa tttcctatgt ttgaaagtga gcatgctaga catgaaatga
    19441 ctgaaaaaat cggtcatgac attcaaccag tagaaacacc tatttttgag ttgaagcatc
    19501 aatttactca tttaacatgg aagattaaag tatacgccgt ttcaggagca attaacattg
    19561 aaacattacc agatgacatg atttggtttg atttaagtga tcgagatcaa tatacattcc
    19621 ctgtacctat gtcaaagatt tatcaattta taaatgggta acattcgatg attggtaata
    19681 ttatcggaaa acatagtgac attaatttta aaaagtataa atgatatctt taaatctcat
    19741 agaataacaa tgtcaaaaag ttaaagtgtt gatatataaa agtgatgatt ttatatactt
    19801 taaatgggac atgtaaatct ctgttgcagt acttagcaat attaccgagt ttaattatta
    19861 agtagtaaaa tcttatttcg taaaaatatg tatttatata atactatttc tgaaatatgc
    19921 tataatttat aatggttaaa ttaacagaag gtggtgtgga gtatggtcag agaatccata
    19981 cctaaagaag gggaaaacat taaaattcag agttataaac atgatggtaa gattcatcgc
    20041 gtttggtctg aaacaacaat attaaagggt actgatcatg ttgtcattgg tggcaatgat
    20101 catacgttag tgactgaaag tgacggaaga acttggataa cacgtgaacc ggcaattgtt
    20161 tactttcact cagaatattg gtttaatgtt atctgcatgt ttagagaaga tggaatttat
    20221 tactattgca atttgtcatc accatttgtt tgtgatgaag aggcattaaa atatatagac
    20281 tatgatttag atattaaagt atatccaaac ggaaagtatc atttattaga tgaagatgaa
    20341 tatgagcaac atatgaatca aatgaattat ccgcatgata ttgatattat tttaagacgc
    20401 aacgtggaca ttcttcaaca atggatagaa cagaagaagg gcccattcgc gccagatttt
    20461 atcaaagttt ggaaagaacg ttacaaaaaa attagacagt attaagcaaa taaagtgtaa
    20521 atactgatta aatcatttat attgacttag tgatgtaaag aagtatgata acttttgctg
    20581 tcgtgtgggg acacagtatc catagattaa attgaataga atataacata cgaataagac
    20641 aacgtattta atcacatgaa tatgacagag gttgagatat cttaatttta aaaatgtaaa
    20701 ttgtaagaag aatttacatc tacaaattat gtatccaacc tctattcatt tttatgctta
    20761 tgaataggat agggcaatag attagggggg gattgtatga ttaaacgata tttgcaattt
    20821 gttaagccat acaaatatcg tatttttgca acgattattg ttggaataat taagtttggt
    20881 ataccaatgc ttataccact tttaattaaa tatgcaatag atggcgtgat taataaccac
    20941 gcactaacga ctgatgaaaa agttcatcat ttaactattg ccattggtat cgcattattt
    21001 atttttgtaa tagtgagacc accaattgaa tttatacgtc aatatttggc gcaatggaca
    21061 agtaataaaa tattgtatga tatacgtaaa aagttataca accatttaca agctttaagt
    21121 gcgagatttt atgctaataa tcaagtaggt caagtaatat ctagagtgat taatgatgtt
    21181 gaacaaacaa aagatttcat tttaaccggg ttaatgaata tttggttaga ttgtataaca
    21241 attattattg cactatccat aatgttcttt ttagatgtga aattgacttt agcagcactg
    21301 tttatcttcc cattttacat tttaacggtg tacgttttct ttggaagatt aagaaaattg
    21361 acgcgtgaga gatcgcaagc attagctgag gttcaaggat tcttgcatga acgtgttcaa
    21421 ggtatttcag tcgttaaaag ttttgcgatt gaagacaatg aagcgaaaaa ctttgataaa
    21481 aagaacacta atttcttaac acgtgctttg aaacatacaa gatggaatgc ctattccttt
    21541 gccgcaatta atacagttac agatattgga ccaataattg tcatcggtgt tggtgcatat
    21601 cttgctattt ctggatcaat cacagtaggt acacttgcag catttgttgg atacttagag
    21661 ttattgttcg ggcctttacg tcgtttagtc gcatcattta caactttaac gcaaagtttt
    21721 gcttcaatgg accgtgtatt ccaattaatt gacgaagatt atgacattaa aaatggtgtt
    21781 ggtgctcaac ctattgaaat taaacaaggt cgtattgata ttgatcatgt tagttttcaa
    21841 tataacgata acgaagctcc aattttaaaa gatattaatt tgagtattga aaaaggagaa
    21901 acagttgctt tcgtaggtat gagtggtggt ggtaaatcaa cattaattaa cttaataccg
    21961 agattttacg atgtaacttc tgggcaaatt ttaatagatg gtcacaacat taaagatttt
    22021 ttaacgggaa gtttaagaaa tcaaatagga ttggtgcaac aggataatat tttattctct
    22081 gatacagtta aggaaaatat tttacttggt cgtccaacag caacagatga agaagtagtt
    22141 gaagcggcga aaatggctaa tgcacatgac tttattatga acttgccaca gggatatgac
    22201 actgaagtag gtgaacgagg tgttaaatta tcaggtggtc aaaaacaaag attatcgatt
    22261 gctagaatat ttttaaataa tccgccaatt cttatcttgg atgaagcaac aagtgcactt
    22321 gatttagaaa gtgaatccat tattcaagaa gcattagatg tgttgagtaa agatcgaacg
    22381 acacttatcg tagcgcatcg cttgtccact attacacatg ctgacaaaat tgtcgtaatt
    22441 gaaaatggac atattgttga aacaggtacg catcgtgaat tgatgtcaaa acaaggtgct
    22501 tacgagcatt tatatagcat tcaaaactta taaagtatta gttgtttgac ttcagtacaa
    22561 tcttgaagag aaaatttgta acaggatggt ggggtcataa catagaaaaa gcagtaagag
    22621 attttcttaa ttgaaaataa tcttactgct ttttttaatt taatttcgag attcaatatt
    22681 actttatctc attgtggtat taattacagg aattgcttta aacttataaa tcaaagtctt
    22741 cttcaacaat ttcaatgtct gcatcagatc tatgatatgt gaaaaagcta attcttatgc
    22801 ggtctaaatg ctctaaatgg tgtcgatact cttcgatggc tgcaacaatt tgcataacat
    22861 tggcaaacga atattccgtt tgataaggat gatttattaa ctcatgctga aatgtggaca
    22921 ataaatcttt tttctgcgga ttatctaact cataatcaac atgtgtcaca ttataacgtg
    22981 cttttttaga aaggctagct aaaatttgct cgtgaaaagc agttaatgaa tctaaatcta
    23041 atttgatttg taataggaaa ttgttattaa gtaaatataa gtcgttttga taacgcgaca
    23101 atttgtttaa tacttcataa gcttgtctag tcgtctgaac tacttctctg aaaagtattt
    23161 tctttctatt ctgttggtga atatgttttt ttgtaatagg acgttcttcg ctatagtaat
    23221 cataaatttt ctctaacttt tcgacacgtt gttttaaatt atgactatct tgtttaatat
    23281 tattaaactc cgtcgtatca tttaatacta atttaaacca cataaaaata tctgaggata
    23341 tatttaatga attatagtaa atttttgttt caaatttagg tggtagaaac acaaagttaa
    23401 ctagagatga acttatgaca ccaatcatta caagtacaaa cctgtaaaag gcggtaatat
    23461 agaaagaacc ggtatgttgt cccataatga ttaatgctgt tacactcgcc aaagtagcaa
    23521 catgtgctaa attaaattta aataaaatag caataagtac tatgacggta acacccataa
    23581 tgataaaatt atcactaaaa attgttacca ttgtaacaga tagtatggca cctataatgt
    23641 tacccaatgc ttgatcagaa actgttttaa atgaacgata aatactaggt tgcattgcaa
    23701 caacagcact gacaccagct aaggctttca gaccaacatc atccggtagt aaagaagcga
    23761 tagacatagc taaaataatg gctataccag ttttaaaaat ccgagctcct agtctcaaaa
    23821 ataatgacgc cccttttaag tttattgaat atctaatatt cgtattcatt actgttatac
    23881 acttactagt tacaaaattc aagcttattt atagttgtta aaataaatca tacataatac
    23941 tgatagtgat gtaaaacttt agtcagagat taaaagagta taaatttgta aaataaaaac
    24001 tcacatagtg acatatcaag ttaaacgtta atagttaacg atataaaatg aatctactat
    24061 gtgagcattt gctttatttt aattcaatta aaaatatact tccttaaaag ttatttcatt
    24121 tgactaaaag catagtctgc agcttttaaa gtttgtttaa tatcttcttc tgtatgttca
    24181 gttgttaaga accaagcttc aaacttagaa ggtgctaaat tgataccttg atttaacatt
    24241 aatttgaaaa atttaccgaa cgcttcgccg tcagaatgtt caacttgatc ataatgtgtg
    24301 actttttcat ctgtaaagta caatgttaaa gatccataaa tacgattaat tgtagctgtg
    24361 atattatgtt tttcgattaa tttaagtaaa ccttcttcta gttgttggcc taagctgtct
    24421 aatttttcat aaacaccgtc ttgttctagt acttcgagta atgcaatacc tgctttcata
    24481 gataatgggt taccagccat tgtaccagct tgatatgcag gtcctagagg tgctacttgt
    24541 tccataatat cttgacgtcc accatagcct ccaattggta aaccaccgcc aacaatttta
    24601 ccaaatgcag ttaaatcagg gataacacct aataaatctt gagcggcacc gtaatggaaa
    24661 cggaatgcag taattacttc atcataaatc actagtgtcc cattgttatg cgaaatttca
    24721 ttaacctctt ctaaaaatcc aggttgaggc attaccattc caaagttacc aacaattggt
    24781 tctactaata ctgcggcaat ttcatcaccc caaaattcaa ttgcttcttt atatgcgtta
    24841 atatcattga aaggtacagt aatgacttca cgtgcgacgc tttctggaac accagctgag
    24901 tctggagaac cgagctgaga tgggccacta cctgctgcaa ccaatactaa atcagaatgg
    24961 ccatgataag atccagcaaa ttttataatt ttatttcttt tagtatatgc acgtgcaaca
    25021 cgaattgttg tcatgactgc ttctgttcca gaatttacaa agcgaatttt ctcaagagat
    25081 ggaattgcat cacgtaattt ttggctgaat tcaatttcta gttcagtcgg tgtaccaaat
    25141 aaaacacctt tagctgcttg ttcttgaatt gctttagtaa tatgaggatg tgcatgcccc
    25201 gtaataattg gaccgtatgc ttgaaggtaa tcaataaatt tattgccatc gacatcatat
    25261 aaatatgcac cgtgtccttc tttcataaca acaggtgcac cgcctcctac agctttataa
    25321 gaacgagaag gggaattgac accgcctaga atatattcgt ttgaaagttg ttgtaaacgt
    25381 tcactttcac taaaattcat ttatatcaac ctcttttaat ttaatatttt catctaatat
    25441 cgtatcataa aattattata atgaagaaaa aggtgattat atgttgcaaa aaggagaaca
    25501 atttccaata tttaaattag aaaatcaaga cggaactgtc attacaaatg atacattaaa
    25561 aggtaaaaag gcgattatat atttttatcc tagagataat acacctactt gtaccacaga
    25621 agcttgtgac tttagagaca atttagaaat gttcaatgat ttagatgttg cagtatatgg
    25681 tataagcggt gattcaaaga aaaaacacca aaattttatt gagaaacacg gattgaattt
    25741 cgatttatta gtagatgaag attttaaatt agctaaagaa actggcgtat atcagttgaa
    25801 aaaatcattt ggcaaagaaa gtatgggcat tgtaagaacg acttttataa tagatgaaca
    25861 aggcaaagta ttagatgtta tcgagaaggt taaggttaaa acacaaatag aagaacttaa
    25921 aaacattttg gggtgacata tatgaaagtt gttgggttaa atcgtatgcg tgaagttgaa
    25981 actgaattac aacaaagctt ttcagattta gattttaaat tttataaaaa agcatcagaa
    26041 atacctgaga gcgacttggc tgatttagat atattagttg gttatgatgg cggtatcaat
    26101 gaggcatttt tacgacgttg cccgaattta aaatggattg catggtttgc tacgggtgta
    26161 aatacattac cgttagatta tattgcagat cacggcatac ttgtaactaa tggaaaaggt
    26221 gttcaagcta aacaattatc tgaatacatt ttagctttca ttttagatga ttataaaaag
    26281 atgaaactat catatgataa ccaacgacaa catatatatg attcgaaaat aactggtaaa
    26341 cgcctatcag gacaaacagt tttattttta ggtacaggtg caattgctac tagaactgcg
    26401 aagttagcaa aggcttttaa tatgaattta attggtctga gcaagtcagg tcagaacaaa
    26461 gatgagtttg acgagatata tactatcgaa tcacttgaaa gcacattacc aaatgctgac
    26521 attattataa atgctttacc agaaacgcaa gaaacgattc atttactaaa gaaaaaacat
    26581 tttgaattaa tgaaagatga agcacttttt ataaatatag gacgaggtag catagttaaa
    26641 gaatcgctct taatagaagt attaaaaagt agagttattc gacatgcgta tttagatgtg
    26701 tttgaaaatg aacctttgaa acctaatcat gaattatatg aattggaaaa tgtaactata
    26761 acagcgcata taactggtaa tgattatgag gcaaagtatg acttattaga tatttttaaa
    26821 aacaatctag ttaattttct caataagaat ggtctaattg agaatgaagt tgatgctaaa
    26881 aaaggctatt aaatgaaatc atcatgtaaa tattgacacg cgcgcaatac tacagttata
    26941 tttatagtaa gtaataataa ttattatata agaaagatgg tgatatagat gagtgttgaa
    27001 atagaatcaa ttgaacatga actagaagaa tcaattgcat cattgcgaca agcaggcgta
    27061 agaattacac ctcaaagaca agcaatatta cgttatttaa tttcttcaca tactcatcca
    27121 acagctgatg aaatttatca agcactttca cctgattttc caaatataag tgttgcgaca
    27181 atatataata acttaagagt gtttaaagat attggaattg taaaagaatt aacatatgga
    27241 gactcatcaa gtcgattcga ctttaataca cataatcatt atcatattat atgtgaacaa
    27301 tgtggtaaga ttgttgattt tcaatatcca cagttaaatg aaattgaaag attagctcag
    27361 catatgactg actttgacgt aacacatcat cgaatggaaa tttatggagt ttgtaaagaa
    27421 tgccaagata aataatttaa ctttggtagt atgacaaatt aaaaaagcgt tagcttactt
    27481 catataagta agtgtaatat ttaagaagtt aaacgacatg aaagttgttt aacttctttt
    27541 ttatgctcat tctgaaaaat atttaaatag aagaaaagaa cattttaact acggaagtgg
    27601 tattaactaa ta
//
LOCUS       DAPSKH010000036        27576 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPSKH010000036 DAPSKH010000000
VERSION     DAPSKH010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 27576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27576
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.036"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(199..1197)
                     /gene="sirC"
                     /locus_tag="RPH49_001616"
     CDS             complement(199..1197)
                     /gene="sirC"
                     /locus_tag="RPH49_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter permease
                     subunit SirC"
                     /protein_id="HDY5124761.1"
                     /translation="MTEKINKKDNYHLIFALIFLAIVSVVSMMIGSSFIPLQRVLMYF
                     INPNDSMDQFTLKVLRLPRITLAILAGAALGMSGLMLQNVLKNPIASPDIIGITGGAS
                     LSAVVFIAFFSHLTIHLLPLFAVLGGTIAMMILLVFQTKGQIRPTTLIIIGISMQTLF
                     IALVQGLLITTKQLSAAKAYTWLVGSLYGATFKDTIILGMVILAVVPLLFLVIPKMKI
                     SILDDPVAIGLGLHVQRMKLIQLITSTILVSMAISLVGNIGFVGLIAPHIAKTIVRGS
                     YAKKLLMSAMIGAISIVIADLIGRTLFLPKEVPAGVFIAAFGAPFFIYLLLTVKKL"
     gene            complement(1194..2189)
                     /gene="sirB"
                     /locus_tag="RPH49_001617"
     CDS             complement(1194..2189)
                     /gene="sirB"
                     /locus_tag="RPH49_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter permease
                     subunit SirB"
                     /protein_id="HDY5124762.1"
                     /translation="MLLKPKYQIVIAGLCLAIVAILSLMIGNTLVSPGTVIQALFNFD
                     SENDLHDVVTGARASRTIIALLTGAALAVSGLLMQALTRNPIASPGLFGVNAGAVFFV
                     IFSITFIQIQSFKMIVVIAFLGAIVVTVLVVALGMFRQTLFSPHRVILAGAAIAMLFT
                     AFTQGILIMNETDLQGLLFWLSGSVSLRNIWDIPWIIPLVLILILIAFSMAAHINILM
                     TSDDIATGLGQNIKLIKWMIIMLISMLAGISVAVAGSIVFVGLIVPNISKRLLPPNYK
                     YLIPFTALAGAILMIISDIVARIIIKPLESPIGVVTAVIGAIVLIYIMKKGRQRL"
     gene            complement(2205..3197)
                     /gene="sirA"
                     /locus_tag="RPH49_001618"
     CDS             complement(2205..3197)
                     /gene="sirA"
                     /locus_tag="RPH49_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B ABC transporter
                     substrate-binding protein SirA"
                     /protein_id="HDY5124763.1"
                     /translation="MNKVIKMLVVTLAFLLVLAGCSGNSNKQSSDNKDKETTSIKHAM
                     GTTEIKGKPKRVVTLYQGATDVAVSLGVKPVGAVESWTQKPKFEYIKNDLKDTKIVGQ
                     EPAPNLEEISKLKPDLIVASKVRNEKVYDQLSKIAPTVSTDTVFKFKDTTKLMGKALG
                     KEKEAEDLLKKYDDKVAAFQKDAKAKYKDAWPLKASVVNFRADHTRIYAGGYAGEILN
                     DLGFKRNKDLQKQVDNGKDIIQLTSKESIPLMNADHIFVVKSDPNAKDAALVKKTESE
                     WTSSKEWKNLDAVKNNQVSDDLDEITWNLAGGYKSSLKLIDDLYEKLNIEKQSK"
     gene            3428..4408
                     /gene="sbnA"
                     /locus_tag="RPH49_001619"
     CDS             3428..4408
                     /gene="sbnA"
                     /locus_tag="RPH49_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000570808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="HDY5124764.1"
                     /translation="MIEKSQACHDSLLDSVGQTPMVQLHQLFPKHEVFAKLEYMNPGG
                     SMKDRPAKYIIEHGIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKIS
                     PTNLKIIKSYGANVEMVEEPDAHGGYLMTRIAKVQELLATIDDAYWINQYANELNWQS
                     HYHGAGTEIVETIKQPIDYFVAPVSTTGSIMGMSRKIKEVHPNAQIVAVDAKGSVIFG
                     DKPINRELPGIGASRVPEILNRSEINQVIHVDDYQSALGCRKLIDYEGIFAGGSTGSI
                     IAAIEQLITSIEEGATIVTILPDRGDRYLDLVYSDTWLEKMKSRQGVKSE"
     gene            4405..5415
                     /gene="sbnB"
                     /locus_tag="RPH49_001620"
     CDS             4405..5415
                     /gene="sbnB"
                     /locus_tag="RPH49_001620"
                     /EC_number="1.5.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-[(2S)-2-amino-2-carboxyethyl]-L-glutamate
                     dehydrogenase SbnB"
                     /protein_id="HDY5124765.1"
                     /translation="MNREMLYLNRSDIEQAGGNHSQVYVDALTEALTAHAHNDFVQPL
                     KPYLRQDPENGHIADRIIAMPSHIGGEHAISGIKWIGSKHDNPSKRNMERASGVIILN
                     DPETNYPIAVMEASLISSMRTAAVSVIAAKHLAKKGFKDLTIIGCGLIGDKQLQSMLE
                     QFDHIERVFVYDQFSEACARFVDRWQQQRPEINFIATENAKEAVSNGEVVITCTVTDQ
                     PYIEYDWLQKGAFISNISIMDVHKEVFIKADKVVVDDWSQCNREKKTINQLVLEGKFS
                     KEALHAELGQLVTGDIPGREDDDEIILLNPMGMAIEDISSAYFIYQQAQQQNIGTTLN
                     LY"
     gene            5436..7190
                     /gene="sbnC"
                     /locus_tag="RPH49_001621"
     CDS             5436..7190
                     /gene="sbnC"
                     /locus_tag="RPH49_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis protein SbnC"
                     /protein_id="HDY5124766.1"
                     /translation="MQNHTAVNTAQTIILRDLVDALLFEDIAGIVSNSDITKENGQTL
                     LIYERETQQIKIPVYFSALNMFRYESSQPITIEGRASKQPLTADEFWQTIANMNCDLS
                     HEWEVARVEEGLTTAATQLAKQLSELDLASHPFVMSEQFASLKDRPFHPLAKEKRGLR
                     EADYQVYQAELNQSFPLMVAAVKKTHMIHGDTANIDELENLTAPIKEQATDMLHDQGL
                     SIDDYVLFPVHPWQYQHILPNVFAKEISEKLVVLLPLKFGDYLSSSSMRSLIDIGAPY
                     NHVKVPFAMQSLGALRLTPTRYMKNGEQAEQLLRQLIEKDEALAKYVTVCDETAWWSY
                     MGQDNDIFKDQLGHLTVQLRKYPEVLAKNDTQQLVSMAALAANNRTLYQMICGKDNIS
                     KNDVMTLFEDIAQVFLKVTLSFMQYGALPELHGQNILLSFEDGRVQKCVLRDHDTVRI
                     YKPWLTAHQLSLPKYVVREDTPNTLINEDLETFFAYFQTLAVSVNLYAIIDAIQDLFG
                     VSEHELMSLLKQILKNEVATISWVTTDQLAVRHILFDKQTWPFKQILLPLLYQRDSGG
                     GSMPSGLTTVPNPMVTYD"
     gene            7183..8439
                     /gene="sbnD"
                     /locus_tag="RPH49_001622"
     CDS             7183..8439
                     /gene="sbnD"
                     /locus_tag="RPH49_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B export MFS transporter"
                     /protein_id="HDY5124767.1"
                     /translation="MINQSIWRSNFRILWLSQFIAIAGLTVLVPLLPIYMASLQNLSV
                     VEIQLWSGIAIAAPAVTTMIASPIWGKLGDKISRKWMVLRALLGLAVCLFLMALCTTP
                     LQFVLVRLLQGLFGGVVDASSAFASAEAPAEDRGKVLGRLQSSVSAGSLVGPLIGGVT
                     ASILGFSALLMSIAVITFIVCIFGALKLIETTHMSKSQTPNINKGIRRSFQCLLCTQQ
                     TCRFIIVGVLANFAMYGMLTALSPLASSVNHTAIDDRSVIGFLQSAFWTASILSAPLW
                     GRFNDKSYVKSVYIFATIACGCSAILQGLATNIEFLMAARILQGLTYSALIQSVMFVV
                     VNACHQQLKGTFVGTTNSMLVIGQIIGSLSGAAITSYTTPATTFIVMGVVFAVSSLFL
                     ICSTITNQINEHTLMKLWELKQKSAK"
     gene            8429..10165
                     /gene="sbnE"
                     /locus_tag="RPH49_001623"
     CDS             8429..10165
                     /gene="sbnE"
                     /locus_tag="RPH49_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2,3-diaminopropanoate--citrate ligase SbnE"
                     /protein_id="HDY5124768.1"
                     /translation="MQNKELIQHAAYAAIERILNEYFREENLYQVPPQNHQWSIQLSD
                     LETLTGEFRYWSAMGHHMYHPEVWLIDGKSKKITTYKEAIARILQYMAQSADNQTAVQ
                     QHMAQIMSDIDNSIHRTARYLQSNTIDYVEDRYIVSEQSLYLGHPFHPTPKSASGFSE
                     ADLEKYAPECHTSFQLHYLAVHKNVLLTRYVEGKEDQVEKVLYQLADINISEIPKDFI
                     LLPIHPYQINVLRQHPQYMQYSEQGLIKDLGVSGDLVYPTSSVRTVFSKALNIYLKLP
                     IHVKITNFIRTNDLEQIERTIDAAQVIASVKDEVETPHFKLMFEEGYRALLPNPLGQT
                     VEPEMDLLTNSAMIVREGIPNYHADKDIHVLASLFETMPDSSMSKLSQVIEQSGLAPE
                     PWLECYLDRTLLPILKLFSNTGISLEAHVQNTLIELKDGIPDVCFVRDLEGICLSRTI
                     ATEKQLVPNVVAASSPVVYAHDEAWHRLKYYVVVNHLGHLVSTIGKATRNEVVLWQLV
                     AHRLMTWKKEYANNAVFVDCVEDLYQTPTIAAKANLMSKLNDCGANPIYTHIPNPICH
                     NKEVSYCESNNS"
     gene            10074..11924
                     /gene="sbnF"
                     /locus_tag="RPH49_001624"
     CDS             10074..11924
                     /gene="sbnF"
                     /locus_tag="RPH49_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(L-alanin-3-ylcarbamoyl)-2-[(2-
                     aminoethylcarbamoyl)methyl]-2-hydroxypropanoate synthase
                     SbnF"
                     /protein_id="HDY5124769.1"
                     /translation="MIVVQTLFIHIYQIQFVITRRYRIVNQTILNRVKTRVMHQLVSS
                     LIYENIVVYKASYQDGVGHFTIEGHDSEYRFTAEKTHSFDRIRITSPIERVVGDEADT
                     TTDYTQLLREAVFTFPKNDEKLEQFIVELLQTELKDTQSMQYRESNPPATPETFNDYE
                     FYAMEGHQYHPSYKSRLGFTLSDNLKFGPDFVPNVKLQWLAIDKDKVETTVSRNVVVK
                     EMLRQQVGDKTYEHFVQQIEASGKHVNDVEMIPVHPWQFEHVIQVDLAEERLNGTVLW
                     LGESDELYHPQQSIRTMSPIDTTKYYLKVPISITNTSTKRVLAPHTIENAAQITDWLK
                     QIQQQDTYLKDELKTAFLGEVLGQSYLNTQLSPYKQTQVYGALGVIWRENIYHMLIDE
                     EDAIPFNALYASDKDGVPFIEKWIKQYGSEAWTKQFLAVAIRPMIHMLYYHGIAFESH
                     AQNMMLIHENGWPTRIALKDFHDGVRFKREHLSEAASHLTLKPMPEAHKKVNSNSFIE
                     TDDERLVRDFLHDAFFFINIAEIILFIEKQYGIDEQRQWKWVKDIIEAYQEAFPELNN
                     YQHFDLFEPTIQVEKLTTRRLLSDSELRIHHVTNPLGVGGINDATTISET"
     gene            11899..12675
                     /gene="sbnG"
                     /locus_tag="RPH49_001625"
     CDS             11899..12675
                     /gene="sbnG"
                     /locus_tag="RPH49_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis citrate synthase
                     SbnG"
                     /protein_id="HDY5124770.1"
                     /translation="MQQLSLKHRLNNGDSVYGIFNSIPDPLMIEVIAASGYDFVVIDT
                     EHVAINDETLAHLIRAAEAAHIIPIVRVTAVIDRDIIKVLDMGARGIIVPHVKDRETV
                     EHIVKLSRYYPQGLRSLNGGRMARFGRTPLLDAMEMANDHIMVIAMIEDVEGVMAIDD
                     IAQVEGLDMIVEGAADLSQSLGIPWQTRDDQVTSHVQHIFEIVNAHGKHFCALPREDE
                     DIAKWQAQGVQTFILGDDRGKIYRHLSASLATSKQKGDEG"
     gene            12675..13877
                     /gene="sbnH"
                     /locus_tag="RPH49_001626"
     CDS             12675..13877
                     /gene="sbnH"
                     /locus_tag="RPH49_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphyloferrin B biosynthesis decarboxylase
                     SbnH"
                     /protein_id="HDY5124771.1"
                     /translation="MRIVQPVIEQLKAQSHPVCHYIYDLVGLEHHLQHITSSLPSNCQ
                     MYYAMKANSERTILDTISQYVEGFEVASQGEIAKGLAFKPANHIIFGGPGKTDEELRY
                     AVSEGVQRIHVESMHELQRLNAILEDEDKTQHILLRVNLAGPFPNATLHMAGRPTQFG
                     ISEDEVDDVIEAALAMPNIHLDGFHFHSISNNLDSNLHVDVVKLYFKKAKAWSEKHRF
                     PLKHINLGGGIGVNYADLTSQFEWDNFVERFKTLIVEQEMEDVTLNFECGRFIVAHIG
                     YYVTEVLDIKKVHGAWYAILRGGTQQFRLPVSWQHNHPFEIYRYKDNPYSFEKVSISR
                     QDTTLVGQLCTPKDVFAREVKIDAISTGDVIVFKYAGAYGWSISHHDFLSHPHPEFIY
                     LTQTKEDE"
     gene            13881..14645
                     /gene="sbnI"
                     /locus_tag="RPH49_001627"
     CDS             13881..14645
                     /gene="sbnI"
                     /locus_tag="RPH49_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional transcriptional
                     regulator/O-phospho-L-serine synthase SbnI"
                     /protein_id="HDY5124772.1"
                     /translation="MNHIHEHLKLVPVDKIDLHETFEPLRLEKTKSSIEADDFIRHPI
                     LVTAMQHGRYMVIDGVHRYTSLKALGCKKVPVQEIHETQYSISTWQHKVPFGVWWETL
                     QQEHRLPWTTETRQEAPFITMCHGDTEQYLYTKDLGEAHFQVWEKVVASYSGCCSVER
                     IAQGTYPCLSQQDVLMKYQPLSYKEIEAVVHKGETVPAGVTRFNISGRCLNLQVPLAL
                     LKQDDDVEQLRNWKQFLADKFANMRCYTEKVYLVEQ"
     gene            14841..15248
                     /locus_tag="RPH49_001628"
     CDS             14841..15248
                     /locus_tag="RPH49_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124773.1"
                     /translation="MSSIIGRITIWIGIVAQIYFSVVFVRMISINIAGGSDYETIFLL
                     GLILTLFTVLPTIFTAIYMESYSVIGGALFIVYAIIALCLYNFLSAILWLIGGILLIW
                     NKYSKDESTDENEKVDIESTENQFESKDKITKE"
     gene            15298..15924
                     /locus_tag="RPH49_001629"
     CDS             15298..15924
                     /locus_tag="RPH49_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124774.1"
                     /translation="MEKNVEKSFIKIGLYFQIAYIVLMAITLCGFVIYYGLIFGLFYL
                     LSGSRADYLIVTIVISAIISIFVIILSIVPVIVLASDLFKERISKGVILIVLAIIALV
                     LCNFVSAILWFVSAISILGRKKLVAAADTTTIQKSKGNANQASHKDTGKKELDSQDMM
                     EHPEFKNPTTKNLEGLNEEIHKDEATTKVDSDNTQPPIESKDHVSKKD"
     gene            16135..16911
                     /locus_tag="RPH49_001630"
     CDS             16135..16911
                     /locus_tag="RPH49_001630"
                     /EC_number="1.1.1.304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-acetoin forming diacetyl reductase"
                     /protein_id="HDY5124775.1"
                     /translation="MTNNKVALVTGGAQGIGFKIAERLVEDGFKVAVVDFNEEGAKAA
                     ALKLSSDGTKAIAIKADVSNRDDVFNAVRQTAAQFGDFHVMVNNAGLGPTTPIDTITE
                     EQFKTVYGVNVAGVLWGIQAAHEQFKKFNHGGKIINATSQAGVEGNPGLSLYCSTKFA
                     VRGLTQVAAQDLASEGITVNAFAPGIVQTPMMESIAVATAEEAGKPEAWGWEQFTSQI
                     ALGRVSQPEDVSNVVSFLAGKDSDYITGQTIIVDGGMRFR"
     gene            17055..17177
                     /locus_tag="RPH49_001631"
     CDS             17055..17177
                     /locus_tag="RPH49_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124776.1"
                     /translation="MHQLKALLVLTHPRYYKTTQKRHYLIYLDKNSQSYLILFL"
     gene            17247..18233
                     /locus_tag="RPH49_001632"
     CDS             17247..18233
                     /locus_tag="RPH49_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDY5124777.1"
                     /translation="MEDLERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENI
                     KNLADDHVFELDIREYDAVEQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVAT
                     LRLLEIIKKYNSHIKRFVFASSAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTL
                     NYCSLYNIPTAVVKFFNVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDF
                     VYVYDVVQSVRLIMEHKDAIGHGYNIGTGTFTNLLEVYRIIGELYGKSVEHEFKEARK
                     GDIKHSYADISNLKALGFVPKYTVETGLKDYFNFEVDNIEEVTAKEVEMSKK"
     gene            18190..18882
                     /locus_tag="RPH49_001633"
     CDS             18190..18882
                     /locus_tag="RPH49_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDY5124778.1"
                     /translation="MKKLQLKKWKCQKNNIEAVHNNKGYAYQRKLDKLEEVRKRYYPI
                     KRAIDLILSIVLLFLTLPIMVIFAIAIVIDSPGNPIYSQVRVGKMGKLIKIYKLRSMC
                     KNAEKNGAQWADKDDDRITNVGKYIRKTRIDELPQLINVVKGEMSFIGPRPERPEFVE
                     LFSSEVIGFEQRCLVTPGLTGLAQIQGGYDLTPQQKLKYDMKYIHKGSLMMELYISIR
                     TLMVVITGEGSR"
     gene            19092..20258
                     /locus_tag="RPH49_001634"
     CDS             19092..20258
                     /locus_tag="RPH49_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDY5124779.1"
                     /translation="MKIIYCITKADNGGAQTHLIQLANHFCVHHDVYVIVGNHGPMIE
                     QLDARVNVIILEHLVGPIDFKQDILAVKVLAQLFSKIKPDVIHLHSSKAGTVGRIAKF
                     ISKSKDTRVVFTAHGWAFTEGVKPAKKFLYLVIEKLMSRITDSIICVSDFDKQLALKS
                     RFNRLKLTTIHNGIADVPAVKQTLKSQSHNNIGEVVGMLPNKQDLQINAPTKHQFVMI
                     ARFAYPKLPQNLIAAIEILKLHNSNHAHFTFIGDGPTLNDCQQQVVQAGLENDVTFLG
                     NVINASHLLSQYDTFILISKHEGLPISIIEAMATGLPVIASHVGGISELVTDNGICMM
                     NNQPETIAKVLEKYLIDSDYIKMSNQSRKRYLECFTEEKMIKEVEDVYNGKSTQ"
     gene            20239..21477
                     /locus_tag="RPH49_001635"
     CDS             20239..21477
                     /locus_tag="RPH49_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDY5124780.1"
                     /translation="MENQHNSKYLTLLLIGLAVFIQQSSVVAGVNVSIADFITLLILV
                     YLLFFANHLLKANHFLQFFIILYTYRMIITLCLLFFDDLIFITVKEVLASTVKYAFVV
                     IYFYLGMIIFKLGNSKKVIVTSYIISSVTIGLFCIIAGLNKSPLLMKLLYFDEIRSKG
                     LMNDPNYFAMTQIITLVLAYKYIHNYIFKVLACGILLWSLTTTGSKTAFIILIVLAIY
                     FFIKKLFSRNAVSVVSMLVIMLILLCFTFYNINYYLFQLSDLDALPSLDRMASIFEEG
                     FASLNDSGSERSVVWINAISVIKYTLGFGVGLVDYVHIGSQINGILLVAHNTYLQIFA
                     EWGILFGALFIIFMLYLLFELFRFNISGKNVTAIVVMLTMLIYFLTVSFNNSRYVAFI
                     LGIIVFIVQYEKMERDRNEE"
     gene            21467..22897
                     /locus_tag="RPH49_001636"
     CDS             21467..22897
                     /locus_tag="RPH49_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDY5124781.1"
                     /translation="MKSDSLKENIIYQGLYQLIRTMTPLITIPIISRAFGPSGVGIVS
                     FSFNIVQYFLMIASVGVQLYFNRVIAKSVNDKRQLSQQFWDIFVSKLLLALTVFAMYI
                     AVITIFIDDYYLIFLLQGIYIIGAALDISWFYAGTEKFKIPSLSNIVASGIVLSVVVI
                     FVKDQSDLSLYVFTIAIVTVLNQLPLFIYLKRYISFVSVNWIHVWQLFRSSLAYLLPN
                     GQLNLYTSISCVVLGLVGTYQQVGIFSNAFNILTVAIIMINTFDLVMIPRITKMSLHQ
                     SHSLTKTLADNMNIQLILTIPMVFGLIAIMPSFYLWFFGEEFASTVPLMTILAILVLI
                     IPLNMLISRQYLLIVNKIRLYNASITIGAVMNLVLCLVLIYFYGIYGAAIARLITEFF
                     LLIWRFIDITKINVKLNIVSTIQCVIAAVMMFIVLGVVNHYLPPTMYATLLLIAIGIV
                     VYLLLMMTMKNQYVWQILRHLRHKTI"
     gene            23165..23764
                     /locus_tag="RPH49_001637"
     CDS             23165..23764
                     /locus_tag="RPH49_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDY5124782.1"
                     /translation="MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVE
                     GTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDI
                     KAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLF
                     DVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK"
     gene            complement(24107..24862)
                     /locus_tag="RPH49_001638"
     CDS             complement(24107..24862)
                     /locus_tag="RPH49_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5124783.1"
                     /translation="MEVVYVTQTQPKFLTIYNTLYKEIQIGKYPSGHALPTEKELCAR
                     FDVSRMTLRQAIKLLAEDGIVESTRGKGHFVIPQTNAQHASSMDQFKHPLDQILLDRV
                     SMSSINYRVDLESEYTNHLFANHPSAVIAMERYYQKKDNHSKQADAFCFTFIPLNVID
                     TFKVNTQNEDDMKTFVEQTIYSNAYQSDLKMSITKAPHFKNHSHVFDGDTHCWLIIET
                     LYAQTPYPIMINKWYIPQEISELTLTRIRQSDY"
     gene            25098..25805
                     /gene="deoD"
                     /locus_tag="RPH49_001639"
     CDS             25098..25805
                     /gene="deoD"
                     /locus_tag="RPH49_001639"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDY5124784.1"
                     /translation="MKSTPHIKPMNDVEIAETVLLPGDPLRAKFIAETYLDDVEQFNT
                     VRNMFGFTGTYKGKKVSVMGSGMGMPSIGIYSYELIHTFGCKKLIRVGSCGAMQENID
                     LYDVIIAQGASTDSNYVQQYQLPGHFAPIASYQLLEKAVETARDKGVRHHVGNVLSSD
                     IFYNADTTASERWMRMGILGVEMESAALYMNAIYAGVEALGVFTVSDHLIHETSTTPE
                     ERERAFTDMIEIALSLV"
     gene            25812..27164
                     /gene="tet(38)"
                     /locus_tag="RPH49_001640"
     CDS             25812..27164
                     /gene="tet(38)"
                     /locus_tag="RPH49_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(38)"
                     /protein_id="HDY5124785.1"
                     /translation="MNVEYSKIKKAVPILLFLFVFSLVIDNSFKLISVAIADDLNISV
                     TTVSWQATLAGLVIGIGAVVYASLSDAISIRTLFIYGVILIIIGSIIGYIFQHQFALL
                     LVGRIIQTAGLAAAETLYVIYVAKYLSKEDQKTYLGLSTSSYSLSLVIGTLSGGFIST
                     YLHWTNMFLIALIVVFTLPFLFKLLPKENNTNKAHLDFVGLILVATIATTVMLFITNF
                     NWLYMIGALIAIIVFALYIKNAQRPLVNKSFFQNKRYASFLFIVFVMYAIQLGYIFTF
                     PFIMEQIYHLQLDTTSLLLVPGYIVAVIVGALSGKIGEYLNSKQAIITAIILIALSLI
                     LPAFAVGNHISIFVISMIFFAGSFALMYAPLLNEAIKTIDLNMTGVAIGFYNLIINVA
                     VSVGIAIAAALIDFKALNFPGNDALSSHFGIILIILGLMSIVGLVLFVILNRWTQSEK
                     "
     gene            27245..>27576
                     /gene="deoC"
                     /locus_tag="RPH49_001641"
     CDS             27245..>27576
                     /gene="deoC"
                     /locus_tag="RPH49_001641"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDY5124786.1"
                     /translation="MKFEKYIDHTLLKPESTRTQIDQIIDEAKAYNFKSVCVNPTHVK
                     YVAERLADSEVLVCTVIGFPLGASTTATKTFETEDAIQNGADEIDMVINIGALKDGRF
                     DDVQQDIEA"
BASE COUNT         9196 a         4244 c         5291 g         8845 t
ORIGIN      
        1 gaaaaatcga agaatattga ttgatattat agaatatgag tcggtgttat ttgtatataa
       61 agtattaata tgtaattaag aaagtcgacg cttgttaaca ttaacaacaa ctatatgtat
      121 aaaaaaacct cgcaactgtt agttaactga atcatttagc taacttcgtt gtgaggtcat
      181 tttgttttga taatatcttt ataacttttt cacggttaat aataagtata tgaagaatgg
      241 ggcaccaaaa gcagcaataa atacacctgc tggcacttct ttaggcaaga ataaggtacg
      301 cccaattaag tctgcaataa caattgatat ggcaccaatc attgctgaca ttagtaactt
      361 tttagcataa cttccgcgaa cgattgtttt cgcgatatgt ggtgcgatta aaccgacaaa
      421 cccaatgtta cctactaaac tgattgccat agatacgagt atagtagaag tgattaattg
      481 gattagtttc atacgttgta catgtaagcc taagccaatc gctacagggt catcaagtat
      541 agatattttc atttttggta taacaagaaa taacaacggc acaacagcta aaataaccat
      601 acccaaaatg attgtatctt taaacgtagc accgtaaaga cttccgacta gccatgtata
      661 agctttggca gcagataatt gcttcgttgt aatgagtaat ccttggacaa gcgcaataaa
      721 caacgtttgc atcgaaatac cgatgattat gagtgttgtc gggcgtattt gtcctttcgt
      781 ttgaaacact aatagtatca tcattgcaat tgtgccacct aatacagcga atagtggaag
      841 taaatgtatc gttaaatggc tgaaaaatgc aataaagaca acagcactta agctagcacc
      901 acctgtgata ccgataatat caggtgaggc aattggattt tttaatacat tttgcaacat
      961 taaaccactc attcctagtg cggcacctgc taaaatcgca agtgtaatgc gaggtaagcg
     1021 taatactttt aaagtgaatt gatccatact gtcatttgga tttataaagt acatcagtac
     1081 gcgttgtaat ggtataaagc ttgaaccaat catcatactt accactgaaa cgatggctaa
     1141 aaagattaac gcgaagatga gatggtaatt gtctttttta ttaatctttt cggtcataag
     1201 cgttgacgtc ctttcttcat aatatagatt aagacaatag cgccaatgac agcggtaacg
     1261 acaccgatag gcgactctag tggcttaatt attatacgag caacaatgtc tgaaatgatc
     1321 attaggattg ctccagctaa tgcagtaaaa ggaattaaat acttatagtt tggtggtaat
     1381 aatcgtttgc taatattcgg tacgataaga cccacaaaga cgattgatcc agctacggct
     1441 accgaaatac cggctaacat actgatgagc ataataatca tccatttgat taattttatg
     1501 ttttgaccga ggccggttgc aatgtcgtca cttgtcatca agatgttgat gtgtgcagcc
     1561 atgctaaatg caattaaaat aagtatcaat acaagcggaa taatccatgg gatatcccaa
     1621 atgttacgta atgaaacgga gccactcaac caaaataata ggccttgtaa gtctgtttcg
     1681 ttcataataa gtatgccttg agtaaaggct gtaaatagca tcgcaatcgc agcacctgcc
     1741 aaaatgacac ggtgaggtga gaatagtgtt tgtctaaaca tacctagcgc aacgactaag
     1801 actgtaacaa caatagcccc caaaaatgcg atgacaacaa tcattttaaa agattgaatt
     1861 tggataaatg taatactaaa gatgacaaaa aatactgcgc ctgcattgac accgaaaagg
     1921 cctggtgatg ctattgggtt tcgtgtaagt gcttgcatca acaaacctga gacagcaagg
     1981 gcagcaccag tcaataacgc aatgattgtt ctcgacgccc gtgcaccagt gacaacatca
     2041 tgtaaatcgt tttcactatc aaagttgaat aacgcctgta tcaccgtacc tggtgacaca
     2101 agcgtatttc caatcattaa acttaagata gctactattg caagacataa accagcaata
     2161 acgatttggt attttggttt aagtagcatc gtaaaactcc ttaattattt tgattgtttt
     2221 tcaatattta acttttcata taaatcgtca atcaatttta atgatgattt atatccgcca
     2281 gctaagttcc aagtgatttc atctaaatca tcagatactt ggttgttttt aactgcgtct
     2341 aaatttttcc actctttact tgaagtccat tcgctttcag tctttttaac taatgcagca
     2401 tctttcgcat ttggatctga ttttactaca aaaatatgat cagcgttcat taacggaatg
     2461 ctttctttag atgtaagttg gataatatct ttaccattat caacttgttt ttgtaagtct
     2521 ttattacgtt tgaatcctaa atcatttaag atttcaccag catatccacc agcataaatt
     2581 cttgtatgat cagcacggaa gttaacaact gaagctttca atggccatgc atctttatac
     2641 tttgcttttg catctttttg gaatgcagct actttatcat cgtacttttt aagtaaatct
     2701 tcagcttctt tttctttccc taaagctttc cccattaact tagttgtatc tttgaatttg
     2761 aaaactgtat cagtagaaac tgttggtgcg attttagata attgatcgta aactttttca
     2821 tttctaactt ttgacgcgac aattaagtcc ggttttaatt tagagatttc ttctaagtta
     2881 ggtgcaggtt cttgacctac aatcttagta tcttttaaat cattttttat gtattcgaat
     2941 ttcggttttt gtgtccatga ttctacagca cctacaggtt taacacctaa agatacagcg
     3001 acgtcagtgg caccttgata tagcgtaaca acacgctttg gtttcccttt aatttcagtt
     3061 gtacccattg catgtttaat tgaagttgtt tccttatctt tgttatcaga tgattgctta
     3121 tttgaattcc cactacatcc tgctaaaaca agtaggaaag caagcgtaac aacaagcatt
     3181 ttaattactt tattcattga ctaattagcc tccttcgtga tgtatgacaa tgagaatcat
     3241 tatcacgatt tagtatgaat taaaattttt cctaagtcaa taaaatattt atgatttaca
     3301 tgcaacttat aattatttga catataaatg cataaaaaat ataatcctaa ttacttgata
     3361 gtgagaatca ttatcaatta ggtaacacac aatattatag aattttaaat ttgaggagga
     3421 agcgcttttg attgaaaaaa gtcaagcatg tcacgattca ttgttagatt ctgtagggca
     3481 aacacctatg gttcaacttc atcaactatt tccgaaacat gaagtgtttg caaagttaga
     3541 gtatatgaat cctggaggca gcatgaaaga tcgacctgcc aagtacatca ttgaacatgg
     3601 tattaaacat ggtttaatca ctgagaatac acatttaatt gaaagtactt ctggtaattt
     3661 aggcattgcg ttggcaatga tagctaaaat caagggatta aaactcacgt gtgttgttga
     3721 tcctaaaata tcaccaacaa atttgaaaat tattaaaagt tatggtgcca atgtagaaat
     3781 ggttgaagaa cctgatgcac atgggggtta tttaatgact cgtattgcaa aggtgcaaga
     3841 actgttagcc actattgacg atgcatattg gattaatcaa tatgcgaatg agttaaattg
     3901 gcaatcccat tatcatggtg caggcacaga gattgttgaa acaattaagc aacctataga
     3961 ttattttgtc gcgccagtca gcacgacagg tagcattatg ggtatgagta gaaaaataaa
     4021 agaagtgcat ccaaacgcac aaattgttgc tgttgatgcg aaagggtcag tcatttttgg
     4081 tgacaaacct attaatagag aattacctgg tatcggtgct agtcgtgtac ccgaaatatt
     4141 gaatagatca gaaattaatc aagtgatcca tgtagatgat tatcaatctg ctttgggctg
     4201 tcgaaaactg attgattatg aaggcatatt tgccggaggt tcaacaggtt cgattattgc
     4261 agcgattgag cagttgataa cgtcaattga agaaggtgca acaattgtca cgattttacc
     4321 agatcgaggc gatcgttact tagatttagt ttattcagat acatggttag aaaaaatgaa
     4381 atcaagacaa ggagttaaat cagaatgaat agagagatgt tgtatttaaa tagatcagat
     4441 attgaacaag cgggaggaaa tcattcacaa gtttatgtgg acgcattaac agaagcatta
     4501 acagcgcatg cgcacaatga ttttgtacaa ccgcttaagc cgtatttaag acaggatcct
     4561 gaaaatggac acatcgcaga tcgaattatt gcaatgccaa gccatatcgg tggagaacac
     4621 gcaatttcag gtattaagtg gataggtagt aagcacgaca atccatcgaa acgtaatatg
     4681 gagcgtgcaa gtggtgtcat tattttgaat gatccggaaa cgaattatcc aattgcagtt
     4741 atggaagcaa gtttaattag tagtatgcgt actgcagcag tttcagtgat tgcagctaag
     4801 catttggcta aaaaaggatt taaagactta acaatcattg gatgcgggct aatcggagac
     4861 aagcaattac aaagtatgtt agagcaattc gatcatattg aacgcgtgtt tgtttacgat
     4921 caattctctg aagcatgtgc acgctttgtt gatagatggc aacaacagcg tccggaaatt
     4981 aattttattg cgacagaaaa tgctaaagaa gcagtatcaa atggtgaagt agtcattaca
     5041 tgtaccgtaa cggatcaacc atacattgaa tatgattggt tacaaaaggg tgcatttatt
     5101 agcaacattt ctatcatgga tgtgcataaa gaagtcttta ttaaagctga caaagtcgta
     5161 gtagatgact ggtcacaatg taatcgagaa aagaaaacta ttaaccaatt ggtgttagaa
     5221 ggtaaattca gcaaagaagc acttcatgct gaactagggc aacttgtgac aggtgacata
     5281 ccaggacgtg aagacgatga tgaaatcata ttacttaatc cgatgggtat ggctatcgaa
     5341 gatatttcaa gtgcttattt tatttatcaa caggcacaac aacaaaatat tgggacaaca
     5401 ttgaacctat attaagaatg cgaggtgtct gaacattgca gaatcataca gcagtcaata
     5461 cagcacaaac gataatatta agggatttag ttgatgcatt attatttgaa gatatagccg
     5521 gaattgtatc gaatagtgat attactaaag aaaatggaca aacgcttttg atatacgaac
     5581 gtgaaacaca acaaataaag atacctgttt attttagtgc tttaaatatg tttcgttatg
     5641 aaagttcaca accaattacg atagagggaa gggcgtctaa gcaaccacta actgcagatg
     5701 aattttggca aacaattgct aatatgaatt gtgatttaag tcatgaatgg gaagtggctc
     5761 gcgttgaaga aggactgact actgctgcca cacagcttgc taaacaatta tcagaattag
     5821 atttagcgtc acatcctttt gtgatgtcag agcagtttgc aagtttaaaa gatcgtccat
     5881 ttcatccatt agctaaagaa aaaagaggat taagagaagc ggattatcaa gtgtatcaag
     5941 ctgaattaaa tcaatcattt cctttaatgg ttgcagcagt taaaaagaca catatgattc
     6001 atggcgatac tgcaaatatt gatgaattag aaaatttgac agcccctata aaagaacaag
     6061 cgacagatat gttacatgat caagggttat caatagatga ctatgtacta tttcctgtac
     6121 atccttggca atatcaacat attttgccga acgtctttgc gaaagagatt agtgaaaaat
     6181 tggttgtact attaccgtta aaatttggag attatctgtc gtcttcaagt atgcgttcat
     6241 taattgatat tggcgcaccg tataaccatg tcaaagtacc atttgcaatg cagtcattag
     6301 gcgcattaag actaacgcct acgcgttaca tgaaaaacgg agaacaagca gaacaattat
     6361 tacgtcagct tatagaaaaa gatgaagcac tagctaagta tgtcacagtt tgcgatgaga
     6421 cagcttggtg gtcatatatg ggtcaagaca atgatatttt caaagatcaa ttaggtcatt
     6481 taactgttca gctaaggaaa tatccagaag tgctagccaa aaatgatacg caacagctag
     6541 tgtcaatggc agcactcgcg gcaaataatc gcaccttata tcaaatgatt tgtggaaaag
     6601 ataatatttc taaaaatgat gtcatgacgt tatttgaaga tatcgcgcaa gtctttttaa
     6661 aggtaacact atcatttatg caatacggcg cattaccaga gttgcatggt caaaatatat
     6721 tgttgtcatt tgaagatgga cgtgtacaaa aatgcgtgtt acgtgatcat gatactgtca
     6781 gaatttataa accatggcta acagcacatc agctttcatt gccgaagtat gtcgtcagag
     6841 aagatacacc taatacgcta attaatgaag atttggaaac attctttgct tattttcaaa
     6901 cattagctgt atcggtaaat ctatatgcca ttattgatgc aattcaagat ttatttggtg
     6961 taagtgagca tgaacttatg tcgttgttaa aacaaatttt aaaaaatgaa gtggcaacta
     7021 tttcctgggt tacaactgat cagctagctg tcagacacat tttatttgat aaacagacgt
     7081 ggccattcaa acaaatttta ttaccattgc tatatcaacg tgatagtggt ggaggtagta
     7141 tgccttcagg tttaactacc gtaccaaatc caatggtgac atatgattaa tcagtctata
     7201 tggcgcagta actttcgcat tttatggctc agtcagttta tagcgattgc tggactgaca
     7261 gtacttgtgc cattattgcc aatttatatg gcatcactac aaaatctatc agtcgtagaa
     7321 atacagttgt ggagtggtat agcgattgct gctcctgctg taacgacgat gatagcttcg
     7381 ccgatatggg ggaagctagg tgataagatc agtcgaaaat ggatggtgtt aagagcgtta
     7441 cttggtttgg cggtatgctt atttttaatg gcattgtgta cgacaccatt acagtttgta
     7501 cttgtgaggt tattgcaggg actatttggt ggtgttgttg atgcatcaag tgcgtttgcg
     7561 agtgcagagg cgccagctga agatcgtggc aaggtattag gaagactgca aagttcagtc
     7621 agcgcagggt ctcttgtggg gccattaatt ggcggtgtta cagcttcgat attaggtttt
     7681 agtgcgttac tgatgagtat tgccgttatt acttttattg tctgtatttt cggtgcatta
     7741 aaattgattg aaacgacaca tatgtcaaaa tcacaaacac caaatattaa taaaggtatt
     7801 cgccgttcat ttcaatgtct attatgcaca caacaaacat gtcgatttat tatcgttggc
     7861 gttttagcaa actttgctat gtatggcatg ctaactgcat tatcaccact tgcttcatca
     7921 gtgaatcata cagcgataga tgaccgtagt gtgattggat ttttacagtc cgcattttgg
     7981 acggcttcga tattaagcgc gcctttatgg ggtcgcttta atgataaatc atatgttaaa
     8041 tcagtatata tatttgcaac gattgcatgt ggttgtagtg cgatactgca aggtttagcg
     8101 acgaatatag agtttttaat ggctgcaagg atacttcaag gattaacata tagtgcattg
     8161 attcaaagtg tcatgtttgt tgtcgtgaat gcgtgtcatc aacaacttaa aggcacattt
     8221 gttggtacga caaatagtat gttagttatt ggccaaatta ttggtagtct tagtggcgct
     8281 gccattacta gttatactac accagctact acgtttatcg ttatgggcgt agtatttgca
     8341 gtaagtagtt tatttttaat ttgttcaacc atcactaatc aaatcaacga gcacacatta
     8401 atgaaattat gggagttgaa acaaaaaagt gcaaaataaa gaattaatac aacatgcagc
     8461 gtatgcggct atcgaacgca ttttaaatga atattttaga gaagaaaatt tatatcaagt
     8521 gccacctcaa aatcatcaat ggtctataca attatcagat ctcgaaacgt taacgggtga
     8581 atttcgctat tggtctgcga tggggcatca tatgtatcat ccagaggtat ggcttattga
     8641 tggaaaaagt aaaaaaataa caacttataa agaagcaatt gcgcgtattt tgcaatatat
     8701 ggctcaaagt gcagataatc aaacggcagt gcaacaacat atggcgcaaa ttatgtctga
     8761 catcgataat agcattcatc gcacggcgcg ttatttgcaa agtaacacaa tagactacgt
     8821 agaggatcgc tatatcgttt cagaacaatc tttatactta ggtcatccat ttcatccgac
     8881 tcctaagagt gcaagtgggt tttcagaagc agatttagag aaatatgcac ccgaatgtca
     8941 tacatcattc caattgcatt atttagctgt gcataaaaat gttctgctca cgcgctatgt
     9001 agaaggtaaa gaagatcagg ttgagaaagt gttgtatcaa ttagcagata taaatatatc
     9061 agagatacct aaagatttta ttttattacc aatacatcct tatcaaatca atgtgttgcg
     9121 acagcatcca cagtatatgc aatatagtga acaaggttta ataaaagacc ttggcgtttc
     9181 cggtgattta gtgtacccga cgtcttcggt tagaactgta ttttcaaaag cattaaacat
     9241 ttatttaaaa ttaccgatac acgttaaaat tactaatttt atacgtacga atgaccttga
     9301 acagattgaa cggacaattg atgccgcgca agttatcgca tcagtcaaag atgaggttga
     9361 aacaccccat tttaaattga tgtttgaaga aggatatcgt gcattgttac cgaatccatt
     9421 agggcaaaca gttgaacctg aaatggattt attaacaaat agtgccatga ttgttcgtga
     9481 agggataccg aattaccatg ctgataaaga tattcatgta ttggcgtcat tatttgaaac
     9541 gatgcctgat tcatcgatgt ctaagttatc acaagtgatt gagcaaagtg gtttagcacc
     9601 agaaccatgg cttgaatgtt atttggatcg tacattattg ccgatattaa agctgtttag
     9661 taacacaggc attagtctag aagcacatgt acaaaataca ttaattgaat taaaagatgg
     9721 catacccgac gtatgctttg tcagagatct tgaaggcatt tgtctatcta gaacgattgc
     9781 tactgaaaaa caacttgtgc caaatgttgt ggcagcatca agccctgttg tatatgcaca
     9841 cgatgaagca tggcatcgtc ttaaatatta tgttgtagta aatcacttag gacatttagt
     9901 atcaactatt ggtaaagcga ctagaaatga agttgtgtta tggcaacttg tagcgcatcg
     9961 tcttatgaca tggaaaaaag aatacgcgaa taacgcagta tttgttgact gtgtagaaga
    10021 tttatatcaa acgccgacca ttgcggctaa agcgaatttg atgagtaaat tgaatgattg
    10081 tggtgcaaac cctatttata cacatatacc aaatccaatt tgtcataaca aggaggtatc
    10141 gtattgtgaa tcaaacaatt cttaatcgtg taaagactag agtgatgcac caactggtat
    10201 catcacttat ttatgagaat attgttgtgt ataaagcgtc atatcaagac ggtgtcggtc
    10261 attttacaat agaaggacat gattcagagt atcgttttac tgctgaaaag acacatagct
    10321 ttgatcgtat acgtatcaca tcaccaattg agcgtgtcgt aggagatgag gcagatacaa
    10381 caacagacta tacacaatta ttgagagaag ctgtatttac atttcctaaa aatgatgaaa
    10441 agctagaaca atttattgtt gagttattac agacagaatt aaaagataca caaagtatgc
    10501 agtatcgaga atcaaaccca ccagcaacac ctgagacatt taacgactat gaattttatg
    10561 cgatggaagg gcatcagtat catccaagtt acaaatcacg tttaggattt acgttgagtg
    10621 ataatttgaa atttggacct gattttgtac caaacgttaa actgcagtgg ttagctatcg
    10681 acaaagataa agtagaaacg acggtatcaa gaaatgttgt agttaaagaa atgttacgtc
    10741 aacaagttgg tgataagact tatgaacatt ttgtacagca aattgaagcg tctggcaaac
    10801 atgtaaatga tgttgagatg atacctgtac acccatggca gtttgaacat gtcatccaag
    10861 ttgatttggc tgaagaaagg cttaatggca cagtactatg gttaggggaa agtgatgagc
    10921 tatatcaccc tcaacaatcg attcgtacga tgtcgccaat agacacgaca aaatattatt
    10981 taaaggtacc aataagtata acgaatactt caacgaaacg agtgttggcg cctcatacaa
    11041 ttgaaaatgc agcgcaaatt acggattggt taaagcagat acagcaacaa gatacgtatt
    11101 taaaagatga attaaagaca gcttttctag gggaagtctt aggacagtct tatttaaata
    11161 cacaactttc gccttataaa caaactcaag tttatggtgc gttaggtgtt atatggcgtg
    11221 aaaatatata tcatatgtta atcgatgaag aggatgcgat accatttaat gcactttatg
    11281 cgagtgataa ggatggtgta ccattcattg aaaagtggat taaacaatat ggttctgaag
    11341 cttggacaaa gcaattttta gctgtagcga ttcgtccaat gattcatatg ctttattatc
    11401 acggtattgc ctttgaatcg catgcacaaa atatgatgct cattcatgaa aatggttggc
    11461 ctacacgtat tgccttaaaa gattttcatg atggtgttcg ttttaagcgt gagcatttaa
    11521 gtgaagctgc ttcacacctg acattaaagc caatgccaga agcacataaa aaagtgaata
    11581 gtaattcatt tattgaaaca gatgacgaac gtttagtacg cgacttttta catgatgcat
    11641 ttttctttat taatatcgcc gaaatcatct tatttattga aaagcaatat ggtatcgatg
    11701 agcagcgaca atggaaatgg gttaaagaca ttatcgaggc gtatcaagaa gcatttccag
    11761 agttgaataa ctatcaacat ttcgatttgt ttgaacctac gattcaagtt gaaaagttaa
    11821 cgacacgtcg attattaagt gactccgagt taagaattca tcatgttaca aatccattag
    11881 gtgtaggagg tataaatgat gcaacaacta tctctgaaac atagattaaa caatggtgat
    11941 tcagtttatg gcatttttaa ttctataccg gacccattga tgatcgaggt tatcgcagca
    12001 agcgggtatg actttgttgt gattgataca gaacacgtgg cgattaatga tgagacacta
    12061 gcgcatttaa ttcgtgcagc tgaagcagcg catattatac caattgtacg tgtcactgca
    12121 gtgatagata gagatatcat taaagtgttg gatatgggtg cgagaggtat tattgtgcca
    12181 cacgttaaag atcgtgagac agttgagcat attgtgaaat taagtcgtta ttacccgcaa
    12241 ggattaagaa gtttgaatgg tggtcgcatg gcaagatttg gacgtacacc attacttgat
    12301 gcaatggaga tggctaatga ccatattatg gtgattgcca tgatagaaga tgttgaaggg
    12361 gttatggcca ttgacgatat agctcaagtc gaaggtttag acatgatagt cgaaggtgcc
    12421 gcagatttat cccagtcact tggcatacca tggcaaacgc gtgatgatca agtaacatca
    12481 catgttcaac atatttttga aattgtgaat gcacatggta aacatttttg tgcattacca
    12541 cgtgaagatg aagatattgc aaaatggcag gcacaaggtg tacaaacatt tattttaggt
    12601 gatgatcgcg gaaaaatata tcgccattta agtgcatctc tagcgacgtc taaacagaaa
    12661 ggggatgaag gctaatgcgt atagttcaac ctgttattga acaattaaaa gcacaatctc
    12721 atccagtttg tcattatatc tatgatttag tcggactgga acatcatttg caacatatta
    12781 catcgtcatt gccgagtaat tgtcaaatgt actatgcaat gaaagcaaat agtgaacgaa
    12841 caatcctaga tacaattagt cagtatgttg aaggattcga agttgcatct caaggtgaaa
    12901 tagcaaaagg tcttgctttt aaaccagcaa atcatattat ttttggtggc cctggtaaga
    12961 cagacgagga actaagatat gcagtaagtg aaggtgttca gcgtattcat gttgaaagta
    13021 tgcatgaatt acaaaggcta aatgccatct tagaagatga agataagaca caacacattt
    13081 tattgcgtgt taatttagca ggaccatttc ccaatgcaac gttgcatatg gcaggacgcc
    13141 ctacacaatt tggtatttct gaagacgaag ttgatgatgt cattgaagct gcgctcgcaa
    13201 tgccaaatat tcatctagat ggatttcatt ttcattctat ttctaacaat ttagactcga
    13261 atttacatgt cgatgtagtg aaactttatt ttaaaaaagc aaaggcatgg tctgaaaaac
    13321 atcgatttcc actcaaacat atcaatcttg gtggtggtat aggggttaac tatgcagatt
    13381 taactagcca atttgagtgg gataattttg tagaacgttt taaaacactt atcgttgagc
    13441 aagaaatgga agatgtgaca ttgaactttg aatgtgggcg ctttattgtg gcacatattg
    13501 gttactatgt gacagaagtg ctagatatta agaaagtgca tggtgcttgg tatgccattt
    13561 taagaggagg tacgcaacaa tttagactgc cggtatcttg gcagcataac catccttttg
    13621 aaatttatcg ctataaggac aatccatatt catttgaaaa agtttcaatt tcgagacagg
    13681 acacaacgtt agtcggtcaa ttatgtacac cgaaagatgt ctttgctaga gaagtaaaga
    13741 tagacgcaat cagtacaggc gacgttattg ttttcaaata tgcaggtgca tacggatggt
    13801 ctatttcaca tcacgatttc ttaagccatc cacatcctga atttatttat ttaacgcaaa
    13861 caaaggagga tgaataacta ttgaatcata ttcatgaaca tttaaaattg gtaccagtag
    13921 ataagattga tcttcacgaa acattcgaac ctttaagatt ggaaaagacg aaaagtagta
    13981 ttgaagcaga tgattttata cgtcatccta ttttagtgac agcgatgcaa catggtagat
    14041 atatggttat agatggtgtg catcggtata caagtttgaa agcgttagga tgtaagaaag
    14101 ttccagtgca agaaatccat gaaacacaat attcaattag tacgtggcaa cataaagttc
    14161 catttggtgt gtggtgggaa acgttacaac aagaacatcg cttgccatgg actactgaga
    14221 caagacaaga agcgccattt attacgatgt gtcatggtga tacagaacaa tatttgtata
    14281 caaaagattt aggcgaagca cattttcaag tatgggaaaa ggttgtcgca agttatagtg
    14341 gttgttgttc tgtagagaga attgcacaag gtacatatcc ttgtctttct caacaagatg
    14401 tactcatgaa gtatcagcca ttgagttata aggaaattga agcggttgtt cataaagggg
    14461 aaactgtgcc agcaggtgtg acacgcttta atatttcagg acgatgtctt aatcttcaag
    14521 taccactggc attgcttaaa caagatgatg atgttgaaca actgcgcaat tggaagcagt
    14581 ttttagcaga taagtttgcc aatatgagat gctatactga aaaagtatac ttggtggagc
    14641 aatagtttta ctgtgatgtt gagggaaata tgatgattta gcgtattgat agcgaaaata
    14701 taataaaaca atatagtgtg gagaactttt gatattttat aaatattgga gttctccatt
    14761 tttgtatttt gcatataaaa attaaataaa ataaggtata ttaaggtaaa gtataaattt
    14821 taaataaatg gggaatgagc atgagctcaa ttataggaag aataacaatt tggataggca
    14881 tcgtagctca aatatatttt agtgtcgttt ttgttaggat gatatctatt aatattgctg
    14941 gaggctctga ttacgaaaca atttttttat taggattaat attgactctt ttcactgttt
    15001 taccaaccat ctttactgcg atttatatgg aaagttactc tgtaatcgga ggtgcacttt
    15061 ttattgttta tgcgattatt gcactgtgtt tatataattt cctttcggca attttatggc
    15121 tgattggtgg tattttgctg atttggaata aatactcaaa agatgaatcg acagacgaaa
    15181 atgaaaaagt tgatattgaa agtacagaga atcaatttga atctaaagat aaaatcacta
    15241 aagaataaag agaatattta aggcggagta taaatattaa ataaatgggg aatagacatg
    15301 gaaaaaaatg tagaaaaatc attcataaag ataggtttat attttcaaat agcttatata
    15361 gtactcatgg ctataacttt atgtgggttt gtaatttact atggactaat tttcggcctt
    15421 ttctatttat tatcaggtag cagagctgat tatttaatag taacaatagt tatatcggca
    15481 ataatttcta tatttgtaat tatactttca atcgtacctg tcatcgtatt ggcatctgac
    15541 ttatttaaag aaaggatttc aaaaggtgtc atattaattg tattggctat tatcgcttta
    15601 gtattatgca actttgtatc tgcaatactc tggtttgttt cagccatatc tattttaggt
    15661 agaaaaaaat tagtagctgc agcagatact accactattc aaaaaagtaa agggaacgca
    15721 aatcaagcat cacataaaga cacgggtaaa aaggaacttg atagtcaaga catgatggaa
    15781 catcctgagt ttaaaaatcc cacgactaaa aacctagaag gattaaacga agaaatacat
    15841 aaagatgaag ctacaactaa agttgacagt gataacacgc aaccgccgat tgaatcaaaa
    15901 gaccatgtct cgaaaaaaga ttgatgacaa actaatcgag agacttaaaa aataatattc
    15961 aacataagca cttttaaagc gacatttaaa cgcattgcca atcactaatg gtagtgcgtt
    16021 taactatacc ttaaatatct gaatattttg ttaaatggag ttatctttgt tgtactattc
    16081 aaatgaagag gagtaaaatg taattaaagg aaagtaattt gaggagtgat ctttatgaca
    16141 aacaacaaag tagcgttagt aactggcggt gcacaaggga ttggttttaa aattgcagaa
    16201 cgtttagtgg aagatggttt caaagtagca gttgttgatt ttaatgaaga aggggcaaaa
    16261 gcagctgcac ttaaattatc aagtgatggt acaaaagcta ttgctatcaa agcagatgta
    16321 tcaaaccgtg atgatgtatt taacgcagta agacaaactg cagcgcaatt tggtgatttc
    16381 catgtcatgg ttaacaatgc cggccttgga ccaacaacac caatcgatac aattactgaa
    16441 gaacagttta aaacagtata tggcgtgaac gttgcaggtg tgctatgggg tattcaagcc
    16501 gcacatgaac aatttaaaaa attcaatcat ggtggtaaaa ttatcaatgc aacatctcaa
    16561 gcaggcgttg agggtaaccc aggattgtct ttatattgca gtacaaaatt cgcagtgcga
    16621 ggtttaacac aagtagccgc acaagattta gcgtctgaag gtattactgt gaatgcattc
    16681 gcacctggta tcgttcaaac accaatgatg gaaagtatcg cagtggcaac agccgaagaa
    16741 gcaggtaaac ctgaagcatg gggctgggaa caatttacaa gtcagattgc tttgggcaga
    16801 gtttctcaac cagaagatgt ttcaaatgta gtgagcttct tagccggtaa agactctgat
    16861 tacattactg gacaaacaat tattgtagat ggtggtatga gattccgtta ataatcatcc
    16921 actaatgata aataaatcct tattgttaag tttaatcact tagcagtaag gattttttag
    16981 tgcacttaga agggattgta ttggtagaaa attaataagc gaagttctta agtgagttat
    17041 gatgtcacag tctaatgcat cagttgaaag cattactagt attaacacac ccaagatatt
    17101 ataaaacaac acaaaaacgc cactatctaa tttatctcga taaaaattca caaagttatc
    17161 tcattttatt tttataaata aaaaatatcg ataaaaagct tacaatactt tatgttttta
    17221 tgatatattt ttaatgtata aatgaggtgg aagatttgga aagagttttg ataactggtg
    17281 gggctggttt tattgggtcg catttagtag atgatttaca acaagattat gatgtttatg
    17341 ttctagataa ctatagaaca ggtaaacgag aaaatattaa aaatttggct gacgatcatg
    17401 tgtttgaatt agatattcgt gaatatgatg cagttgaaca aatcatgaag acatatcaat
    17461 ttgattatgt tattcattta gcagcattag ttagtgttgc tgagtcggtt gagaaaccta
    17521 tcttatctca agaaataaac gttgtagcaa cattaagatt gttagaaatc attaaaaaat
    17581 ataatagtca tataaaacgt tttgtctttg cttcgtcagc agctgtttat ggtgatcttc
    17641 ctgatttacc taaaagtgat caatcattaa tcctaccatt atcaccatat gcaatagata
    17701 aatattacgg cgaacggacg acattaaatt attgctcgtt atataacata ccaacagcgg
    17761 ttgttaaatt ttttaatgta tttgggccaa gacaggatcc taagtcacaa tattcaggtg
    17821 tgatttcaaa gatgttcgat tcatttgagc ataacaagcc atttacattt tttggtgacg
    17881 gactgcaaac tagagatttt gtatatgtat atgatgttgt tcaatctgta cgcttaatta
    17941 tggaacacaa agatgcaatt ggacacggtt ataacattgg tacaggcact tttactaatt
    18001 tattagaggt ttatcgtatt attggtgaat tatatggaaa atcagtcgag catgaattta
    18061 aagaagcacg aaaaggagat attaagcatt cttatgcaga tatttctaac ttaaaggcat
    18121 taggatttgt tcctaaatat acagtagaaa caggtttaaa ggattacttt aattttgagg
    18181 tagataatat tgaagaagtt acagctaaag aagtggaaat gtcaaaaaaa taacattgaa
    18241 gctgtccata ataataaggg ttatgcctat caaagaaaat tagacaaact agaagaagtg
    18301 agaaaaagat attacccaat taaacgtgcg attgacttaa ttttaagcat tgttttatta
    18361 tttttaactt taccgattat ggttatattc gccattgcta tcgtcataga ctcaccagga
    18421 aaccctattt atagtcaggt tagagttggg aagatgggta aattaattaa aatatacaaa
    18481 ttacgttcga tgtgtaaaaa cgcagagaaa aatggtgcgc aatgggctga taaagatgat
    18541 gatcgtataa caaatgtcgg gaagtatatt cgtaaaacac gcattgatga attaccacaa
    18601 ctaattaatg ttgttaaagg ggaaatgagt tttattggac cacgcccgga acgtccggaa
    18661 tttgtagaat tatttagttc agaagtgata ggtttcgagc aaagatgtct tgttacacca
    18721 gggttaacag gacttgcgca aattcaaggt ggatatgact taacaccgca acaaaaactg
    18781 aaatatgaca tgaaatatat acataaaggt agtttaatga tggaactata tatatcaatt
    18841 agaacattga tggttgttat tacaggggaa ggctcaaggt agtcttaatt tacttaataa
    18901 gttcaaataa aagttacatt ttaaagattg tgaccaattg ttacagtata acgaggaatc
    18961 ccttgagaca gtatcaaatg gcattaagaa atatgtgcca tcattgattt gcgtggctat
    19021 aaatactatt catctgatga gatagccatg ttaagaaatt gaaagtatag cattaaaggg
    19081 gtttgtaaca gttgaaaatt atatattgta ttactaaagc agacaatggt ggtgcacaaa
    19141 cacatctcat tcaactcgcc aaccattttt gcgtacacca tgatgtttat gtcattgtag
    19201 gcaatcatgg accaatgatt gaacaactag atgcaagagt taatgtaatt attctcgaac
    19261 atttagtagg tccaattgac tttaaacaag atattttagc tgtcaaagtg ttagcacagt
    19321 tattctcgaa aattaaacct gatgttatcc atttacattc ttccaaagct ggaacggtcg
    19381 gacgaattgc gaagttcatt tcgaaatcga aagacacacg tgtagttttt actgcacatg
    19441 gatgggcttt tacagagggt gttaaaccag ctaaaaaatt tctatattta gttatcgaaa
    19501 aattaatgtc acgtattaca gatagcatta tttgtgtttc agatttcgat aaacagttag
    19561 cgttaaaatc tcgctttaat cgattgaaat taaccacaat acataatggt attgcagatg
    19621 ttcccgctgt taagcaaacg ctaaaaagcc aatcacataa caatattggc gaagtagttg
    19681 gaatgttgcc taataagcaa gatttacaga ttaatgcccc gacaaagcat caatttgtta
    19741 tgattgcaag atttgcttat ccaaaattgc cacaaaatct aatcgcggca atagagatat
    19801 tgaaattaca taacagtaat catgcgcatt ttacatttat aggcgatgga cctacattaa
    19861 atgattgtca gcaacaagtt gtacaagctg ggttagaaaa tgatgtcaca tttttgggca
    19921 atgtcattaa tgcgagtcat ttattatcac aatacgatac gtttatttta ataagtaagc
    19981 atgaaggttt gccaattagc attatcgaag ctatggctac aggtttgcct gttatagcca
    20041 gtcatgttgg cggtatttca gaattagtaa ctgataatgg tatatgtatg atgaacaacc
    20101 aacccgaaac tattgccaaa gtcctggaaa aatatttaat agacagtgat tacatcaaaa
    20161 tgagtaatca atctagaaaa cgttatttag aatgttttac tgaggagaaa atgattaaag
    20221 aagtggaaga cgtttataat ggaaaatcaa cacaatagta aatatctaac attgttactt
    20281 atcggtttag cggtttttat tcagcaatct tcggttgttg ctggtgtgaa tgtatctata
    20341 gctgacttta ttacattact aatattagtt tatttactgt tttttgctaa ccatttatta
    20401 aaggcaaatc attttttaca gtttttcatt attttgtata cataccgtat gattattacg
    20461 ttgtgtttac tattttttga tgatttgata tttattacgg ttaaggaagt tcttgcatct
    20521 acagttaaat atgcatttgt agtcatttat ttctatttag ggatgatcat ctttaagtta
    20581 ggtaatagca aaaaagtaat cgttacctct tatattataa gcagtgtgac tataggtcta
    20641 ttttgtatta tagctggttt gaacaagtcc cctttactaa tgaaattgtt atattttgat
    20701 gaaatacgtt caaaaggatt aatgaatgac cctaactatt tcgcgatgac acagattatt
    20761 acattggtac ttgcttacaa gtatattcat aattacatat tcaaggtcct tgcatgtggc
    20821 atcctgctat ggtctttaac tacaacggga tctaagactg cgtttatcat attaatcgtc
    20881 ttagccattt atttctttat taaaaagtta tttagcagaa atgcggtaag tgttgtgagt
    20941 atgttagtga ttatgctgat attactttgt tttacctttt ataatatcaa ctactattta
    21001 ttccaattaa gcgaccttga tgccttaccg tcattagatc gaatggcgtc tatttttgaa
    21061 gaggggtttg catcattaaa tgatagtgga tctgagcgaa gtgttgtatg gataaatgcc
    21121 atttcagtaa ttaaatatac attaggtttt ggtgttggct tagtggatta tgtacatatt
    21181 ggctcgcaaa ttaatggtat tttacttgtt gcccataata catatttgca aatttttgcg
    21241 gaatggggca ttttattcgg tgcgttattt atcatattta tgctttattt actgtttgaa
    21301 ttatttagat ttaacatttc tggtaaaaat gtaacagcaa ttgttgtaat gttgacgatg
    21361 ctgatttact ttttaacagt atcgtttaat aactcaagat atgtcgcttt tattttagga
    21421 attatcgtct ttattgttca atatgaaaag atggaaaggg atcgtaatga agagtgattc
    21481 actaaaagaa aatattattt atcaagggct ataccaattg attagaacga tgacaccact
    21541 gattacaata cccattattt cacgtgcatt tggtcccagt ggtgtgggta ttgtttcatt
    21601 ttctttcaat atcgtgcaat actttttgat gattgcaagt gttggcgttc agttatattt
    21661 taatagagtt atcgccaagt ccgttaacga caaacggcaa ttgtctcagc agttttggga
    21721 tatctttgtt agtaaattat tattagcgtt aacagttttt gcgatgtata tcgctgtgat
    21781 tacaatcttt atagatgatt actatcttat tttcctacta caaggtatct atattatagg
    21841 tgcagcactc gatatttcat ggttttatgc tggaactgaa aagtttaaaa tacctagcct
    21901 tagtaatatt gttgcgtctg gtattgtatt aagtgtcgtt gttatctttg tcaaagatca
    21961 atcagattta tcattgtatg tatttactat tgctattgtg acggtattaa accaattacc
    22021 tttgtttatc tatttaaaac gatacattag ctttgtttcg gttaattgga tacacgtctg
    22081 gcaattgttt cgttcgtcat tagcatactt attaccaaat ggacagctca acttatatac
    22141 tagtatttct tgcgttgttc ttggtttagt aggcacatac caacaagttg gtatcttttc
    22201 taacgcattt aatattttaa cggtcgcaat cataatgatt aatacatttg atcttgtaat
    22261 gattccgcgt attactaaaa tgtctttaca tcaatcacat agtttaacta agacgttagc
    22321 agataatatg aacattcaat tgatattaac aatacctatg gtctttggtt tgattgcaat
    22381 tatgccatca ttttatttat ggttctttgg tgaggaattc gcatcaactg tcccattgat
    22441 gaccatttta gcgatacttg tattaatcat tcctttaaat atgttgataa gcaggcaata
    22501 tttattaata gtgaataaaa taagattata taatgcgtca atcactattg gtgcggtaat
    22561 gaatttagta ttatgtcttg ttttgatata tttttatgga atttacggtg ctgctattgc
    22621 gcgtttaatt acagagtttt tcttgctcat ttggcgattt attgatatta ctaaaatcaa
    22681 tgtgaagttg aatattgtaa gtacgattca atgtgtcatt gctgccgtta tgatgtttat
    22741 tgtgcttggt gtggtcaatc attatttgcc tcctacaatg tacgctacgc tgctattaat
    22801 tgctattggt atagtagttt atcttttatt aatgatgact atgaaaaatc aatacgtatg
    22861 gcaaatattg aggcatcttc gacataaaac aatttaagta tcggtaacgc tatactttag
    22921 gaatttaaga ttaagaagaa aaggcaattt cttattgaaa aatggaagtt gtctttttta
    22981 attcttttta aaagcgggaa acaaaagcag ttaaatgcct ttttgcattc aatattaaat
    23041 attatatcaa ttccgaatat ttaaatttta tataattgga tataacaaat aaataataat
    23101 tattgcaaaa cacacccgaa attaattatt ataaaagtat attcataaaa ggaggaatat
    23161 acttatggca tttaaattac caaatttacc atatgcatat gatgcattgg aaccatatat
    23221 agatcaaaga acaatggagt ttcatcacga caaacatcac aatacgtacg tgacgaaatt
    23281 aaacgcaaca gttgaaggaa cagagttaga gcatcaatca ctagcggata tgattgctaa
    23341 cttagacaag gtaccggaag cgatgaggat gtcagtccgt aataatggcg gtggtcattt
    23401 taaccattca ttattctggg aaatactatc acctaattct gaagaaaaag gtggcgtaat
    23461 agacgacatt aaagcgcagt ggggcacttt agatgaattt aaaaatgaat ttgcaaataa
    23521 agcaacaaca ttatttggat caggttggac ttggttagtt gttaatgatg gaaaattaga
    23581 aattgtgaca acgccaaacc aagataatcc attaacagaa ggcaaaacac caatcttact
    23641 atttgatgtt tgggagcatg cctactatct gaaatatcaa aataaacgtc cagactatat
    23701 gactgcattt tggaatattg ttaactggaa aaaagttgat gaattatacc aagcagcaaa
    23761 ataatataac ttaatataat tgaggtggag catctacaag gtgtttcacc ttttttgtat
    23821 gtatgaggta atcaatttgc tttttgtata atgggttgga gaatcaaatg taggtaaaac
    23881 agtacaatca tttacaatga tgaatacttt acttgtgttc tctgtgcttg tgaactcaat
    23941 gtttcgagaa gagcgcacat cgaataacaa aattatttag acaacgttca acaaataaat
    24001 aaacatcata cgttttaaag tagaaaaaat catgtgatta cctgaaagtt attgtcgatt
    24061 aaacaatagc taaacagtca tcacatgatt ttttatttta ataattttaa taatccgatt
    24121 gtcttatacg tgtcagtgtt aattcagata tttcctgtgg aatataccac ttattaatca
    24181 taattggata aggtgtttgt gcgtacaatg tttcaataat cagccaacaa tgtgtatcac
    24241 catcaaacac gtgactatga tttttgaagt ggggcgcttt ggtaatagac atttttaaat
    24301 ctgattgata tgcattgcta taaatcgtct gctcaacgaa cgtcttcatg tcgtcttcgt
    24361 tttgtgtatt cactttaaat gtgtcaatga catttaacgg tataaaggta aaacaaaatg
    24421 catcagcttg cttagaatga ttgtcctttt tttgataata gcgttccatt gcaatgacgg
    24481 cagaaggatg gtttgcaaac aaatgatttg tatattcact ttctaaatca acacgataat
    24541 taattgatga catagataca cgatctagca atatttgatc aagtggatgc ttaaattgat
    24601 ccatacttga agcgtgttgg gcatttgttt gtggaataac gaagtgtccc ttccctcttg
    24661 tactctctac gatgccatct tcggccaaca attttatagc ttggcgcaaa gtcatacgac
    24721 tgacatcaaa gcgcgcacaa agttcctttt cagtaggtaa tgcatggcca ctcggatatt
    24781 ttcctatttg aatttcttta tataacgtat tataaatcgt taaaaatttt ggttgtgttt
    24841 gcgtcacgta gacaacctcc ataaagttac ttaatcactc tcatcataca ataattttta
    24901 ctcgaattgg aaaaattata aaaattaaac atagataggc tttgaaaatt agttttatac
    24961 aaggttagaa gctataactg taaaatgttc ttaatattgt caaaatgtaa tgcttgaaag
    25021 cgcttttaaa aaatattatt atatacatgg ttagacaaat agacaaatca ctatacaaat
    25081 attgggagga atattttatg aaatcaacac cacacattaa gccaatgaat gacgtcgaaa
    25141 ttgcagaaac ggtgctattg ccaggagatc cgttaagagc taagttcatt gcagaaacat
    25201 atttggacga tgtggaacag ttcaatacag tgcgaaacat gtttggtttt accggaacat
    25261 ataaaggtaa aaaagtttct gtcatgggtt caggtatggg tatgccatct attggcattt
    25321 actcttatga attaattcat acatttggtt gtaaaaaatt aattcgcgtt ggttcttgtg
    25381 gcgcgatgca agaaaacatt gatttatatg atgtgattat tgcacaaggt gcctctactg
    25441 attcaaatta cgttcaacaa tatcaattac caggtcattt tgcgccaatt gcttcttatc
    25501 agttattaga aaaagcagtt gaaacagcac gtgacaaagg tgtacgtcat catgtaggta
    25561 atgtgttatc aagtgatatt ttctataacg cggatacaac agcgagtgaa cgttggatgc
    25621 gtatgggtat tttaggtgta gaaatggaat cagctgcatt atacatgaat gcaatttacg
    25681 ctggtgtcga agcattaggt gtgttcacag tgagcgatca tttaattcat gaaacgtcaa
    25741 caacacctga ggaaagggaa cgtgcattta cagatatgat tgaaattgca ctgtcattgg
    25801 tgtagatgat tatgaatgtt gaatattcta aaataaagaa agcagtacct attttattat
    25861 tcttatttgt attcagtttg gttatagaca actcattcaa attgatttct gtagccattg
    25921 ctgatgactt aaacatttct gtaactacag taagttggca agcgacatta gccggtttag
    25981 taattggtat tggcgctgta gtatacgctt cattatctga tgccattagt atacgcacac
    26041 tatttattta tggcgtgata ttaatcatta tcggatcaat tattggttac attttccaac
    26101 atcaattcgc attactttta gttggacgta ttattcaaac tgcaggttta gctgctgcag
    26161 agacattata tgtgatatat gttgcaaagt atctttctaa agaggaccag aagacttacc
    26221 ttggcttaag tacgagcagt tattccttgt cattagttat cggtacatta tcaggtggat
    26281 ttatttctac gtatttacac tggacaaata tgtttttaat tgcattaatc gtagtattta
    26341 cgttgccatt cctatttaaa ttattaccaa aagaaaataa tacaaataaa gctcatttag
    26401 attttgttgg cttaattcta gtggcaacta ttgctacaac agtcatgctg tttattacga
    26461 actttaattg gttatatatg attggtgctt taattgcgat tatcgttttt gcgctatata
    26521 ttaaaaatgc gcaacgtcca ttagtaaaca aatcattttt ccaaaataaa cgttatgctt
    26581 catttttatt tatagtattc gtaatgtatg ctatccaatt gggttatatt tttacgttcc
    26641 cattcataat ggaacaaatt tatcatcttc aactagacac aacatcactg ttattagtac
    26701 cgggttatat tgtagcagtc atcgttggtg cactaagtgg taaaatcggc gaatatctta
    26761 attcaaaaca agcgattatc acagcaatta ttttaatcgc actgagctta attttacctg
    26821 catttgcagt aggtaatcac atttcaatct tcgtcatttc tatgatattc tttgcaggta
    26881 gctttgcttt aatgtatgca cctttactta acgaagccat taaaacaata gatcttaata
    26941 tgacaggtgt ggctattggt ttttataatt taattattaa tgtggcggta tctgtaggta
    27001 ttgcgattgc tgcggctcta atcgatttta aagcattaaa tttcccaggc aatgatgcat
    27061 taagttcaca tttcggtatt attttaatta ttttaggttt aatgagtatt gtcggattag
    27121 ttttattcgt catcttaaat cgttggacac aatctgaaaa ataaatagat ataaattcgc
    27181 gagatatatt cgtatttata gtaaaattaa ataaagagat tatataacac gaggagtagt
    27241 aagtatgaaa tttgagaaat atatagatca cactttattg aagcctgagt caacacgtac
    27301 gcaaatcgat caaatcatcg atgaagcgaa agcatacaat tttaaatctg tatgtgtgaa
    27361 tccaacgcat gttaaatatg tagcagagcg actagctgat tcagaggtgc tagtttgtac
    27421 ggtaatagga ttcccattag gtgcgtcgac aactgcaacg aaaacatttg aaacagaaga
    27481 tgcaattcaa aatggtgcag atgaaattga catggtcatc aacatcggcg cattaaaaga
    27541 tgggcgtttt gatgatgtac aacaagacat tgaagc
//
LOCUS       DAPSKH010000037        26391 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPSKH010000037 DAPSKH010000000
VERSION     DAPSKH010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 26391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26391
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.037"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            1..935
                     /locus_tag="RPH49_001642"
                     /pseudo
     CDS             1..935
                     /locus_tag="RPH49_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
     gene            complement(1051..3117)
                     /locus_tag="RPH49_001643"
     CDS             complement(1051..3117)
                     /locus_tag="RPH49_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIABC"
                     /protein_id="HDY5124787.1"
                     /translation="MFKKLFGQLQRIGKALMLPVAILPAAGILLAFGNAMHNEQLVEI
                     APWLKNDIIVMISSVMEAAGQVVFDNLPLLFAVGTALGLAGGDGVAALAALVGYLIMN
                     ATMGKVLHITIDDIFSYAKGAKELSQAAKEPAHALVLGIPTLQTGVFGGIIMGALAAW
                     CYNKFYNITLPPFLGFFAGKRFVPIVTSVVAIATGVVLSFAWPPIQDGLNSLSNFLLN
                     KNLTLTTFIFGIIERSLIPFGLHHIFYSPFWFEFGSYTNHAGELVRGDQRIWMAQLKD
                     GVPFTAGAFTTGKYPFMMFGLPAAAFAIYKNARPERKKVVGGLMLSAGLTAFLTGITE
                     PLEFSFLFVAPVLYGIHVLLAGTSFLVMHLLGVKIGMTFSGGFIDYILYGLLNWDRSH
                     ALLVIPVGIVYAIVYYFLFDFAIRKFKLKTPGREDEETEIRNSSVAKLPFDVLDAMGG
                     KENIKHLDACITRLRVEVVDKSKVDVAGIKALGASGVLEVGNNMQAIFGPKSDQIKHD
                     MAKIMSGEITKPSETTVTEEMSDEPVHVEALGTTDIYAPGVGQIIPLSEVPDQVFAGK
                     MMGDGVGFIPEKGEIVAPFDGTVKTIFPTKHAIGLESESGVEVLIHIGIDTVKLNGEG
                     FESLINVDEKVTQGQPLMKVNLAYLKSHAPSIVTPMIITNLENKELVIEDVQDADPGK
                     LIMTVK"
     gene            complement(3418..5157)
                     /locus_tag="RPH49_001644"
     CDS             complement(3418..5157)
                     /locus_tag="RPH49_001644"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDY5124788.1"
                     /translation="MAKIKANEALVKALQAWDIDHLYGIPGDSIDAVVDSLRTVRDQF
                     KFYHVRHEEVASLAAAGYTKLTGKIGVALSIGGPGLIHLLNGMYDAKMDNVPQLILSG
                     QTNSTALGTKAFQETNLQKLCEDVAIYNHQIEKGDNVFEIVNEAIRTAYEQKGVAVVI
                     CPNDLLTEKIKDTTNKPVDTSRPTVVSPKYKDIKKAVKLINKSKKPVMLIGVGAKHAK
                     DELRAFVEAAKIPVVHSLPAKTILPDDHPYSIGNLGKIGTKTSYQTMQDADLLIMVGT
                     NYPYVDYLPKKNIKAIQIDTNPKNIGHRFNINVGIVGDSKIALHQLTENIKHVAERPF
                     LNKTLERKAVWDKWMEQDKNNNSKPLRPERLMASINKFIKDDAVISADVGTATVWSTR
                     YLNLGVNNKFIISSWLGTMGCGLPGAMASKIAYPNRQAIAIAGDGAFQMVMQDFATAV
                     QYDLPLTVFVLNNKQLAFIKYEQQAAGELEYAVDFSDMDHAKFAEAAGGKGYTIKSAS
                     EVDAIVEEALAQDVPTIVDVYVDPNAAPLPGKIVNEEALGYGKWAFRSITEDKHLDLD
                     QIPPISVAAKRFL"
     gene            complement(5204..5893)
                     /locus_tag="RPH49_001645"
     CDS             complement(5204..5893)
                     /locus_tag="RPH49_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDY5124789.1"
                     /translation="MNDYVQALLMILLTVVLYYFAKRLQQKYPNPFLNPALIASLGII
                     FVLLIFGISYNGYMKGGSWINHILNATVVCLAYPLYKNREKIKDNVSIIFASVLTGVM
                     LNFMLVFLTLKAFGYSKDVIVTLLPRSITAAVGIEVSHELGGTDTMTVLFIITTGLIG
                     SILGSMLLRFGRFESSIAKGLTYGNASHAFGTAKALEMDIESGAFSSIGMILTAVISS
                     VLIPVLILLFY"
     gene            complement(5886..6281)
                     /gene="cidA"
                     /locus_tag="RPH49_001646"
     CDS             complement(5886..6281)
                     /gene="cidA"
                     /locus_tag="RPH49_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin-like murein hydrolase modulator CidA"
                     /protein_id="HDY5124790.1"
                     /translation="MHKVQLIIKLLLQLGIIIVITYIGTEIQKIFHLPLAGSIVGLFL
                     FYLLLQFKIVPLTWVEDGANFLLKTMVFFFIPSVVGIMDVASEITLNYILFFAVIIIG
                     TCIVALSSGYIAEKMSVKHKHRKGVDAYE"
     gene            complement(6494..7372)
                     /locus_tag="RPH49_001647"
     CDS             complement(6494..7372)
                     /locus_tag="RPH49_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5124791.1"
                     /translation="MDIKHMKYFIEVVKQGGMTNASKSLYIAQPTISKAIKDIENEMG
                     TPLFDRSKRHLILTDAGQIFYEKSKEIVALYDYLPSEMERLNGLETGHINMGMSAVMN
                     MKILINILGAFHQQYPNVTYNLIENGGKTIEQQIINDEVDIGVTTLPVDHHIFDYTTL
                     DKEDLRLIVSREHRLAKYETVKLEDLAGEDFILFNKDFYLNDKIIENAKNVGFVPNTV
                     AQISQWHVIEDLVTNELGISILPTSISEQLNGDVKLLRIEDAHVHWELGVVWKKDKQL
                     SHATTKWIEFLKDRLG"
     gene            7539..7757
                     /locus_tag="RPH49_001648"
     CDS             7539..7757
                     /locus_tag="RPH49_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sterile alpha motif-like domain-containing
                     protein"
                     /protein_id="HDY5124792.1"
                     /translation="MSFYEFMQSFLGDDTPLGELVDWINQDSNFPREVKSHSEILSYF
                     RTNPCPESISVPVIKRALSVFNQFTNVQ"
     gene            8146..8577
                     /locus_tag="RPH49_001649"
     CDS             8146..8577
                     /locus_tag="RPH49_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5124793.1"
                     /translation="MEYKKILIRLLIAFAVLFSADFTYQSVEQTHQSHAAVNYYSKNQ
                     CTWWAFKRRAQVGKPVSNKWGNAKNWYNNARKSKYATGRTPRKFAVMQSTAGYYGHVA
                     VVEQVYKNGSIKVSEYNFYRPLKYNTRVLSKKAARNFNYIY"
     gene            complement(8716..9993)
                     /locus_tag="RPH49_001650"
     CDS             complement(8716..9993)
                     /locus_tag="RPH49_001650"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDY5124794.1"
                     /translation="MQNLDKNFRHLSRKEKLQQLVDKQWLSEEQFDILLNHPLIDEEV
                     ANSLIENVIAQGALPVGLLPNIIVDDKAYVVPMMVEEPSVVAAASYGAKLVNQTGGFK
                     TVSSERIMIGQIVFDGVDDTEKLSADIKALEKQIHKIADEAYPSIKARGGGYQRIAID
                     TFPEQQLLSLKVFVDTKDAMGANMLNTILEAITAFLKNEFPQSDILMSILSNHATASV
                     VKVQGEIDVKDLARGERTGEEVAKRMERASVLAQVDIHRAATHNKGVMNGIHAVVLAT
                     GNDTRGAEASAHAYASRDGQYRGIATWRYDQDRQRLIGTIEVPMTLAIVGGGTKVLPI
                     AKASLELLNVESAQELGHVVAAVGLAQNFAACRALVSEGIQQGHMSLQYKSLAIVVGA
                     KGDEIAKVAEALKQEPRANTQAAERILQEIRQQ"
     gene            10247..11413
                     /locus_tag="RPH49_001651"
     CDS             10247..11413
                     /locus_tag="RPH49_001651"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDY5124795.1"
                     /translation="MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAV
                     SPVNQDIVSMGANAAKDIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFA
                     RCFEMKEACYAATPAIQLAKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAM
                     VIAHNPSILALNQDAVAYTEDVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAK
                     RQGKSLADFASLCFHVPFTKMGKKALESIIDNADETTQERLRSGYEDAVDYNRYVGNI
                     YTGSLYLSLISLLENRDLQAGETIGLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKAL
                     LNNRTEVSVDAYETFFKRFDDVDFDEEQDAVHEDRHIFYLSNIENNVREYHRPE"
     gene            complement(11584..12105)
                     /locus_tag="RPH49_001652"
     CDS             complement(11584..12105)
                     /locus_tag="RPH49_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDY5124796.1"
                     /translation="MVYKSYYDSPVGRLELLSDGVSLTAVLFENQQGDGNREENTSLA
                     IFKEATQWLDAYFKGDNPEITIPLKPTGSDFQQCVWNELRQIPYGTLTTYGAIAKKVG
                     KVLDKPKMSAQAVGGAVGSNPLSIIVPCHRVVGKTGSLTGFGGTINNKIKLLELENID
                     MSKLYVPKHSTKP"
     gene            12468..14576
                     /gene="clpL"
                     /locus_tag="RPH49_001653"
     CDS             12468..14576
                     /gene="clpL"
                     /locus_tag="RPH49_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpL"
                     /protein_id="HDY5124797.1"
                     /translation="MNNNFFNSDFDSILRRMMQDMQSSNQTSNKKYYINGKEVSPEEL
                     AQFTQQGGNHSAEQSAQAFQQAALRQQGQQGGNGNYLEQIGRNLTQEARDGLLDPVIG
                     RDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
                     DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLS
                     DILKPALSRGEISIIGATTQDEYRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIR
                     EKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITAAHLSAQSPAIDKVA
                     TEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTI
                     QRLTGIPVSQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPI
                     GSFLFVGPTGVGKTELAKQLAIDLFGNKDALIRLDMSEYSDTTAVSKMIGTTAGYVGY
                     DDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVINFKNTI
                     IICTSNAGFGNGTDQEYDDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLL
                     DDVQVTLDKKGITMNVSQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHT
                     DVKHVDLDIEDNELVVKGKS"
     gene            complement(14643..14813)
                     /locus_tag="RPH49_001654"
     CDS             complement(14643..14813)
                     /locus_tag="RPH49_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDY5124798.1"
                     /translation="MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDIDRDCCG
                     TEQHTANHFPGK"
     gene            complement(14826..16820)
                     /gene="feoB"
                     /locus_tag="RPH49_001655"
     CDS             complement(14826..16820)
                     /gene="feoB"
                     /locus_tag="RPH49_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDY5124799.1"
                     /translation="MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLK
                     ENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLE
                     LNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKHLLGEIKHLGE
                     GYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEV
                     VNKLSSLRDQVAKQVEAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKIL
                     THKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFL
                     QDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKS
                     FIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQ
                     SLVVLSLYVLGIIMAFLVSTVLTKTVLKNDNAIFIVELPTYRVPSIKTLWRSTWEKAK
                     GFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQA
                     GATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVST
                     VAAIRKETYSWKWTALAVAYPLVTAYVLTFIFYQVGHLFV"
     gene            complement(16832..17059)
                     /locus_tag="RPH49_001656"
     CDS             complement(16832..17059)
                     /locus_tag="RPH49_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDY5124800.1"
                     /translation="MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQ
                     KCLFKGPCIIEVNGQQLSIRHCDACSIALEE"
     gene            complement(17275..19764)
                     /gene="farE"
                     /locus_tag="RPH49_001657"
     CDS             complement(17275..19764)
                     /gene="farE"
                     /locus_tag="RPH49_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid efflux MMPL transporter FarE"
                     /protein_id="HDY5124801.1"
                     /translation="MAKFLYKMGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDND
                     IKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITKDIKKTLDDIKK
                     DDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNV
                     QTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGII
                     SLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYVKGIGLAVGTAG
                     SAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVVFAVLSALTLLPALISIFHKRI
                     KVNKLQSKFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPA
                     DSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDI
                     VTPPQMSKDNDYALMVVIPKQGPNAESTNDLVHDLRDYHRDAQDKYGFKTEISGQSVI
                     NIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLV
                     MQDGFMKGLFGIETTGPILAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYS
                     IKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIP
                     ALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKVY
                     PQGATNVSKYQDVHGQDDAHSIVLDDKTMALYQEVKQQSASSLFLYDALIDYQNKHQL
                     NSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS"
     gene            19909..20457
                     /gene="farR"
                     /locus_tag="RPH49_001658"
     CDS             19909..20457
                     /gene="farR"
                     /locus_tag="RPH49_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid efflux pump transcriptional regulator
                     FarR"
                     /protein_id="HDY5124802.1"
                     /translation="MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHR
                     TTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLRDIAEFQ
                     EEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSHIPDNLIFYIYDSLIEGFMHWIKDE
                     KIDWPGEEIDKIFHKIINIKIK"
     gene            complement(20534..20701)
                     /locus_tag="RPH49_001659"
     CDS             complement(20534..20701)
                     /locus_tag="RPH49_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124803.1"
                     /translation="MRYVISIIMAIVLAIWSLKQLSQSHLDSGFIFFFIVYVLCISYF
                     NSDKHDKNKKR"
     gene            complement(20813..22357)
                     /gene="pruA"
                     /locus_tag="RPH49_001660"
     CDS             complement(20813..22357)
                     /gene="pruA"
                     /locus_tag="RPH49_001660"
                     /EC_number="1.2.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glutamate gamma-semialdehyde dehydrogenase"
                     /protein_id="HDY5124804.1"
                     /translation="MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGE
                     KIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAANEAYKSWKTWSANDRAELML
                     RVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDR
                     EGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLM
                     EILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEG
                     QNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYD
                     EVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDS
                     KGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITN
                     NREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQK
                     VVSEMF"
     gene            complement(22547..23146)
                     /locus_tag="RPH49_001661"
     CDS             complement(22547..23146)
                     /locus_tag="RPH49_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDY5124805.1"
                     /translation="MTEKEKMLAEKWYDANFDQDLINERARAKDICFELNHTRPSDTI
                     KRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVF
                     IGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAG
                     SVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK"
     gene            23385..23576
                     /gene="cwrA"
                     /locus_tag="RPH49_001662"
     CDS             23385..23576
                     /gene="cwrA"
                     /locus_tag="RPH49_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall inhibition responsive protein CwrA"
                     /protein_id="HDY5124806.1"
                     /translation="MRILITGTVAILIILGLVKTIQDYEMTNDTSRQMSDNKDDDKVI
                     HLNNFKNLHAKEFNPSDFF"
     gene            23816..26224
                     /locus_tag="RPH49_001663"
     CDS             23816..26224
                     /locus_tag="RPH49_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDY5124807.1"
                     /translation="MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKA
                     TVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQN
                     ATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIK
                     LIISAILSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLR
                     NGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEA
                     RAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKII
                     KGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVE
                     EAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIA
                     CPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHLIDTIVLDKTGTITNGRPVVT
                     DYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDH
                     HHILVGNRKLMADNDISLPKHISDDLTHYERDGKTAMLIAVNYSLTGIIAVADTVKDH
                     AKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQG
                     KKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKAT
                     IRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPR
                     RKDA"
BASE COUNT         8616 a         4984 c         4102 g         8689 t
ORIGIN      
        1 aataccagag ataaaagaag atggatatag cgatttaaca atagaagaaa tagatttaat
       61 tggtagtcat ttagataaag aaatcgaaga tttaaatcat tctattgaga acgaagattg
      121 tgctcaaatt agaaaataga cccgtaaaaa agaactaaga ttaagaagtt caaaaataaa
      181 tttgatgatt attctgaaag aaaaagtaaa tatgaagagc aaaaatcgat tcttaaagat
      241 agaaatagct tttctaaaac tgatcatgat gcaactttta tgagaatgaa agaagaccat
      301 atgaaaaatg gccaacttaa gccaggatac aatttacaaa tagcgacaaa ttctcaattt
      361 gttttatcct atgacctatt tcaaaatcca acagatactg gaacattaat tccattttca
      421 acactcaaaa ttggaaatat gacgaactta atgatgaatt tatatgtcct aataacaaaa
      481 gaataggttt taaaagatat gcataccata atgatagata tggttttaaa cgagacttca
      541 aactatatga atgtgatgac tgttcatcat gttctttgag acatcaatgc atgaagccaa
      601 attcgaaatc caataagaaa attatgaaga attataattg ggaatacttt aaagcccaaa
      661 ttaatcaaaa gcgttctgaa ccagaaacga aaaaaatcta tagtcaaaga aaaattgatg
      721 tagagcctgt ttttggattt atgaaagcta ttttgagttt cattcgtatg tcagttcgag
      781 gaataaataa agttaaacga gagctaggtt ttgtattaat ggcacttaat ataaggaaaa
      841 tagcagctca acgagctgta cattataaaa tacatatcaa aaaagctaat ttctatcaaa
      901 taattaatag aaatcagctt ttttacattg cctaagaact taatgtctca agctcttttg
      961 taacgtattc tgtttcaact cgctacttcg catacgcact acgaatgaca aaaagttcat
     1021 tcatttgata tgctgtttca tttttaatca ttatttgact gtcataatta gcttacctgg
     1081 atcagcatct tgtacatctt caatgacaag ttctttattt tcaagatttg taataatcat
     1141 tggtgtaacg atgcttggtg cgtgtgattt caagtatgct aaattcactt tcattaatgg
     1201 ttgaccttgt gttacttttt catcaacgtt aatcagactt tcgaatcctt cgccattcag
     1261 tttcactgta tcgataccaa tatgaataag tacttcgaca ccactttcag attctaatcc
     1321 tatcgcatgt ttcgtaggga agattgtttt cactgtacca tcaaacggtg ctacaatttc
     1381 acctttttca gggataaagc caacaccatc acccatcatt ttaccagcga atacttgatc
     1441 aggtacttct gataatggaa tgatttgacc gacacctggt gcatagatat ctgttgttcc
     1501 aagtgcttct acgtgaactg gttcatctga catttcttca gtcactgtcg tttcacttgg
     1561 tttcgtaatt tcaccactca taatcttggc catatcatgt ttaatttgat ctgattttgg
     1621 accaaagata gcttgcatat tgtttccaac ttctaataca cctgatgcgc ctaaagcttt
     1681 aatacctgct acatctactt ttgatttatc aaccacttct acgcgcagac gtgtaataca
     1741 tgcatctaaa tgtttaatgt tttcttttcc acccattgca tctaagacat caaatggtaa
     1801 ttttgcgaca ctagagttac gaatttcagt ttcttcatct tcacgacctg gtgttttcaa
     1861 tttaaactta cgaattgcaa agtcgaataa gaagtaatac acgatagcat atacaatacc
     1921 gactggaata actaataatg cgtgtgaacg atcccagttt aataaaccat ataaaatata
     1981 atctatgaaa ccacctgaga atgtcatacc aattttaacg cctaataaat gcattactaa
     2041 gaatgatgta ccagctaata atacgtgaat tccataaagt actggtgcta caaataagaa
     2101 tgaaaattct aatggctcag tgataccagt taaaaatgca gttaatcctg ctgataacat
     2161 taaaccaccc acgacttttt tacgttctgg tcgtgcattt ttataaatcg caaatgctgc
     2221 cgctggtaaa ccaaacatca taaatggata tttaccagta gtaaatgcac cagcagtaaa
     2281 tggtacgcca tctttcaatt gtgccatcca aatacgttgg tcaccacgaa ctaattcacc
     2341 tgcgtgattt gtataactac cgaattcaaa ccagaacggt gaatagaaaa tatgatgtaa
     2401 accaaatgga attaatgagc gttcaataat accgaatata aacgttgtta atgttaaatt
     2461 tttatttaat aagaaattcg ataaactatt taatccgtct tgaattggtg gccacgcaaa
     2521 gcttaaaacc acacctgttg caatcgctac gaccgatgtc acaatcggta caaatcgttt
     2581 acctgcaaag aatcctaaaa atggtggtag tgtaatgtta taaaatttgt tgtagcacca
     2641 tgcggctaaa gcacccatga taataccgcc aaacacaccc gtttgtaatg ttggaatacc
     2701 taatactaag gcatgtgccg gttctttcgc tgcttgactt aattcttttg cccctttggc
     2761 atatgagaaa atgtcatcaa ttgtaatgtg caacactttc cccattgttg cattcataat
     2821 taagtaacct actagcgctg ctaatgctgc aacaccgtct cctcctgcta atccaagtgc
     2881 tgtaccaact gcaaataata atggcaagtt atcaaataca acttgtcctg ctgcttccat
     2941 gaccgacgaa atcattacaa tgatatcgtt ttttaaccat ggtgcaattt ctactaattg
     3001 ttcgttgtgc attgcgttac caaacgctaa taaaatacca gctgctggta aaatcgcaac
     3061 aggtaacatt aatgctttac cgatacgttg caattgtcca aacaatttct taaacatata
     3121 aacatcccct atctcaattt ccgcttccat gtacaaaaaa agcaggcatg aacaaacaag
     3181 actattctca tagtgcggtt gtttgctcat gcctgcatta ccagtaacac gcaagtgata
     3241 tctaattcat agctattata catatttgta aaagcgtttt caacaacttt ttcacaattt
     3301 tatcatcaat tcagtacgat catttgtgat aaataaacaa aacggcaatt cccattttgt
     3361 tgaaatagaa attaccgttt ttatagttca attcaattgt gataaccttt aaatcagtta
     3421 taagaaacgt tttgctgcca ctgaaattgg tggaatttga tctaaatcta aatgcttatc
     3481 ttcagtaatt gatctaaatg cccacttacc ataaccaagc gcttcttcat ttacaatttt
     3541 acctggtaat ggcgcagcat taggatcaac atatacatct acaatcgttg gtacatcttg
     3601 tgctaatgcc tcttcgacta tagcatctac ttcgctagca ctcttaattg tataaccttt
     3661 accacctgct gcctcagcaa attttgcatg atccatatca gaaaaatcaa ctgcatattc
     3721 taattcacca gctgcttgtt gttcatattt aataaatgct aactgtttgt tattaagtac
     3781 aaatacagtt aaaggtaaat catattgtac tgctgtagcg aagtcttgca ttaccatttg
     3841 gaatgcaccg tcaccagcaa tggcaatcgc ttgtctattt ggatatgcaa tttttgatgc
     3901 catagctcct ggaagaccgc aacccattgt acctaaccaa cttgaaatga tgaacttgtt
     3961 gttcacacca agatttaaat aacgtgtaga ccaaactgtt gcagtaccaa catctgctga
     4021 aattactgca tcatctttaa taaatttgtt aattgatgcc attaaacgtt ctggacgtaa
     4081 tggtttgcta ttattatttt tatcttgttc catccattta tcccaaaccg ctttacgttc
     4141 taacgttttg tttaaaaatg gtctttccgc aacatgttta atattttcag ttaactgatg
     4201 caatgcaatt ttactgtctc caacaattcc tacattaata ttaaaacgat gtccgatatt
     4261 tttaggattt gtgtcgattt ggattgcttt aatatttttc ttaggtaagt aatctacata
     4321 tggatagttt gtacctacca taattagtaa atctgcatcc tgcattgtct gatatgaggt
     4381 ttttgtacct attttaccta agttaccaat actgtatgga tggtcatccg gtaagattgt
     4441 cttagcaggt aatgaatgaa cgaccggaat ttttgccgct tcaacaaacg cacgtagctc
     4501 atctttcgca tgttttgcac caacaccaat caacataacc ggctttttac tcttattgat
     4561 taatttaaca gcttttttaa tgtctttata ttttggtgat acaacagttg gtcttgatgt
     4621 atctactggt ttattcgttg tatctttaat tttttcagtt aataagtcgt taggacaaat
     4681 aacaacagct acaccttttt gttcatatgc cgtacgaatt gcttcgttaa caatttcaaa
     4741 cacattgtca cctttttcaa tttggtgatt ataaatggct acatcttcac ataatttttg
     4801 taaatttgtt tcttggaatg ctttcgttcc aagtgctgta ctattcgttt gtccagataa
     4861 tattaattgc ggtacattat ccattttggc atcatacata ccatttaata aatgaattaa
     4921 accagggcca ccgatactta atgccacacc gattttacca gttaattttg tgtaaccagc
     4981 agccgctaag cttgctactt cttcatgacg tacatgataa aatttaaatt gatctctcac
     5041 tgtacgtaaa ctatcgacta ctgcgtcgat tgagtctcct ggaataccat acaagtgatc
     5101 tatatcccat gcttgtaatg ctttaactaa tgcttcattt gcttttattt ttgccattat
     5161 tactaatagc ctccctttct gtctatcatt ttaaatatct aaattaatag aataataaaa
     5221 ttagaacagg tattaacact gaactaataa ctgcagttaa aatcatccca attgaactaa
     5281 atgcaccgga ttcaatatcc atttctagtg ctttagctgt gccaaatgca tgtgacgcat
     5341 tcccatacgt taaacctttg gcgatagaag attcaaatct tccaaatctt aataacatcg
     5401 aacctaaaat actaccgatt aaacccgttg tgataataaa aagtacggtc atcgtatctg
     5461 taccacctag ttcatgtgac acttcgatac ctactgcggc tgttatagat cggggcaata
     5521 acgttacaat gacgtcttta gaatagccaa atgctttaag tgttaagaac actaacatga
     5581 aattcagcat gacgccagtt aatacacttg caaaaatgat agagacattg tctttaattt
     5641 tctctctatt tttataaagt gggtacgcta aacatacgac cgttgcgttt aaaatatggt
     5701 tgatccaact gccacctttc atatacccgt tataactaat tccaaagata agtaagacaa
     5761 aaataattcc taaagatgca attaatgctg gattcaaaaa tgggttcgga tatttttgtt
     5821 gtaacctttt agcgaaataa tataaaacga cagtcaacaa aatcattaat aaggcttgca
     5881 cgtaatcatt cataagcgtc tacaccttta cgatgtttat gtttaacaga cattttttca
     5941 gcaatataac ctgaagataa tgcaacgata catgttccta tgataatgac tgcgaaaaag
     6001 agtatataat ttagcgtaat ttcggaagca acatccataa tacctacaac tgacggtatg
     6061 aagaaaaaga ccatcgtctt taataaaaag tttgcaccgt cttctaccca agttagcggt
     6121 acaatcttaa attgtaatag taaataaaat aaaaatagac caacaatact gccggctaag
     6181 ggaagatgaa aaatcttttg aatttctgtg ccaatataag taatcacaat gatgattcct
     6241 agttgtagta gtagtttgat tattaattgg actttgtgca tggcgccatc cctttctaaa
     6301 tatgtctaaa ttgttacaat aactattata aagatggcgt acacaatata aaaatactct
     6361 ttttttatag tttgtattac tattttctat ggaaacgctc tctaaatttc acttcatttt
     6421 cacaaaaaaa cactcattat ttcaatgacc cacgtaatga tgcgccttaa ataatgagtg
     6481 ctttattaat atgttagcct aaacggtctt tcaaaaattc tatccatttc gttgtggcat
     6541 gacttaattg tttatccttc ttccaaacaa cacctaattc ccaatgtaca tgagcatctt
     6601 caatgcgtag cagcttcaca tctccattta gttgctctga aattgatgtt ggtaaaatac
     6661 taatacctaa ttcattcgta actaaatctt ctataacatg ccattgtgaa atttgcgcta
     6721 cagtattcgg aacaaagcca acgtttttag cattttcaat aattttatca ttcaagtaaa
     6781 agtctttatt aaataaaatg aagtcttcac ctgctaaatc ttcgagttta acagtttcat
     6841 attttgcgag tcgatgctct ctgctcacga taagtcgcaa atcttcctta tctagggtag
     6901 tataatcgaa aatatgatga tcgactggca aagtggtcac gcctatatct acttcatcat
     6961 tgataatttg ctgttcaatc gttttgccgc cattttctat taaattatat gtaacatttg
     7021 gatattgttg atggaatgca ccaagaatat tgataagaat cttcatattc atgactgccg
     7081 acatacccat gtttatatgc cctgtttcca gtccattcaa gcgttccatt tcagatggta
     7141 aataatcata cagtgcaaca atttctttac ttttctcata aaaaatttga cctgcatcgg
     7201 taagaattaa atgtctttta cttctatcaa ataagggcgt gcccatttca ttttcaatat
     7261 ctttaattgc tttactaatt gtaggttgtg caatatataa tgatttggaa gcattagtca
     7321 tgcccccttg cttaacgact tcaataaaat atttcatatg tttgatatcc actaacatca
     7381 tcctaactat ttcaacacgt ttatttcatt atacacaact tcttaaacat tcaataaatt
     7441 tagatttata aaattgcttt ataaaaagtt tcatgtaaaa tacacattct tttatggtat
     7501 tatattaatg gctcaagttt gttattcgag gtgaggtatt gagcttttac gaatttatgc
     7561 aaagttttct tggtgatgac acaccattag gtgaattggt tgattggatt aatcaagata
     7621 gcaatttccc tagagaagtg aagagccata gtgaaatatt gtcatatttt cgaacaaatc
     7681 catgtcctga aagcatctca gtacctgtaa ttaaacgggc actatcagtt ttcaaccaat
     7741 tcacaaatgt acaatgatac atgaatacat ggagtcacat catctcatgt tagcgctctg
     7801 attgcagggc gctattttta atgttatcgc tacatttagt atgttgtgat tgctattttc
     7861 tttcagttat aaaaccacgt accttttctt ttaaatcatt tatattttcc cactaatatc
     7921 cgctgttaat caattctgac atccttgtat cactatgaca attaattgtt aaatacatta
     7981 atttctacat tttatgaaaa aatccatttt tattacaatt caacacttta tatgacaact
     8041 tcattacagt tacttttatt gttgattgct tgcattgttt tctaaaaaaa ttttgttatc
     8101 ataaataacg ttgaataaag aaaaaaatta acttgggaga taaaaatgga atataaaaag
     8161 atactaattc gtttattaat tgcttttgca gtacttttct cagcagattt cacttatcaa
     8221 tccgtcgaac aaacgcatca atcgcatgcc gcagttaatt attatagtaa aaaccaatgt
     8281 acatggtggg catttaaacg tcgcgcacaa gttggcaaac ctgtctctaa caaatggggt
     8341 aatgccaaaa attggtataa caatgcacgt aaatcaaaat atgcgactgg tcgtacacca
     8401 agaaaatttg ctgtaatgca atcaactgca ggatattatg gacatgtcgc agttgttgaa
     8461 caagtatata aaaacggtag tattaaagtt tcagaataca acttttatcg cccattaaaa
     8521 tacaatacac gtgtactaag caaaaaggca gcacgtaact ttaactatat ttactaatca
     8581 aaaaacttct atcacgaacg cttcaatttc ctgtatgcgt gtgatagaag tttttatttt
     8641 ttgttcatat taatttattt aagcgctacg atggactgac ttaaactttt ctttaaaatc
     8701 gctattcgca atttactatt gttgtctaat ttcttgtaaa atacgttccg ctgcttgtgt
     8761 atttgcacgg ggttcttgct tcaatgcttc agctacttta gcaatttcat caccttttgc
     8821 tcctacaacg atagctaatg atttatattg taaactcata tgaccttgtt gaataccttc
     8881 tgacacaagc gcgcgacatg ctgcaaagtt ttgcgctaaa ccaacggcag caactacatg
     8941 acctaattct tgtgctgact ctacatttag tagctctaat gaagctttag ctattggcaa
     9001 tactttcgta ccacccccaa caattgctaa tgtcattggc acttcaattg taccaatcaa
     9061 tcgttgacga tcttgatcgt aacgccatgt agcaatacca cgatactgtc cgtcacgact
     9121 cgcatatgca tgcgcacttg cttctgcacc acgcgtatca tttcctgttg ctaaaacaac
     9181 agcatgtatg ccattcataa cacctttatt atgtgttgca gcacgatgaa tatcaacttg
     9241 tgccaataca gaagcacgtt ccattcgttt ggcaacctct tccccagttc tctcgcccct
     9301 tgctaaatct ttaacatcaa tttcgccttg aactttaaca acggacgctg ttgcatgatt
     9361 ggataaaata ctcattaaaa tatcgctttg cggaaattca ttttttaaaa atgcagttat
     9421 ggcctctaaa atcgtattaa gcatattagc gcccatagca tctttcgtat caacaaatac
     9481 ttttaaagat agtaactgtt gctcaggaaa tgtatcaatc gctatacgtt ggtaaccacc
     9541 accacgcgct ttaatagaag gatatgcctc atccgcaatt ttatgaattt gcttttctaa
     9601 agctttaatg tctgctgata atttttcagt atcgtcaacg ccatcaaaga cgatttgacc
     9661 tatcataata cgttcagaag ataccgtttt aaatccgcca gtctgattca ctagctttgc
     9721 accataacta gctgcagcga caactgaagg ctcttccacc atcataggta caacatatgc
     9781 cttatcgtcc acaatgatat tcggtaataa tccaacgggt aatgcacctt gcgcgatgac
     9841 attttcaatt aaactattgg ctacttcttc atcgattaat ggatgattca gtaaaatgtc
     9901 gaattgttct tctgataacc attgcttatc aaccaattgt tgtaactttt ctttacgaga
     9961 taaatgtcga aaattcttat ctaaattttg catggacgta ctccttttac ttcacataat
    10021 ttttaacatt tcaatcacta ctatttttac cacaaaataa cgtcattcgt cttaaaattc
    10081 aattgaataa ttgtcgtttt gactttaaaa taaaacaagg taaattaaaa cgcttacaag
    10141 aaacgacaaa tcatttttaa atttagtata tttctttgta taaaattagc atattctgat
    10201 atgatacaag tgttgctttt ataaatttga aaggatgtaa aaccttatga caataggtat
    10261 cgataaaata aacttttacg ttccaaagta ctatgtagac atggctaaat tagcagaagc
    10321 acgccaagta gatccaaaca aatttttaat tggtattggt caaactgaaa tggctgttag
    10381 tcctgtaaac caagacatcg tttcaatggg cgctaatgct gctaaggaca ttataacaga
    10441 cgaagacaaa aagaaaattg gtatggtaat tgtggcaact gaatcagcag ttgatgctgc
    10501 taaagcagcc gctgttcaaa ttcacaactt attaggtatt caaccttttg cacgttgctt
    10561 tgaaatgaaa gaagcttgtt atgctgcaac accagcaatt caattagcta aagattattt
    10621 agcaactaga ccgaatgaaa aagtattagt tattgctaca gatacagcac gttatggatt
    10681 gaattcaggc ggcgagccaa cacaaggtgc tggcgcagtt gcgatggtta ttgcacataa
    10741 tccaagcatt ttggcattaa atcaagatgc tgttgcttac actgaagacg tttatgattt
    10801 ctggcgtcca actggacata aatatccatt agttgatggt gcattatcta aagatgctta
    10861 tatccgctca ttccaacaaa gctggaatga atacgcaaaa cgtcaaggta agtcgctagc
    10921 tgacttcgca tctctatgct tccatgttcc atttacaaaa atgggtaaaa aggcattaga
    10981 gtcaatcatt gataacgctg atgaaacaac tcaagagcgt ttacgttcag gatatgaaga
    11041 tgctgtagat tataaccgtt atgtcggtaa catttatact ggatcactat atttaagcct
    11101 aatttcatta cttgaaaatc gtgatttaca agctggtgaa acaatcggtt tattcagtta
    11161 tggctcaggt tcagttggtg aattctatag tgcgacatta gttgaaggct acaaagatca
    11221 tttagatcag gctgctcaca aagcattatt aaataaccgt actgaagtat ctgttgatgc
    11281 atatgaaaca ttcttcaaac gttttgatga cgtagacttt gacgaagaac aagatgctgt
    11341 tcatgaagat cgccatattt tctacttatc aaatattgaa aataacgttc gcgaatatca
    11401 cagaccagag taatctgtgt atttgaaaga catttaaata taacctaaaa acagcagtaa
    11461 gaccacttct aattgaaatc gtcttactgc tgttttctat ttataatgct tcgtcttgaa
    11521 tgaattcatt atgcctattt gacatattat taaagttttc ctaatgcctg gatcctttat
    11581 acgttacggc ttcgtgctat gttttggtac ataaagcttt gacatatcga tattctccaa
    11641 ctctaacagc ttaattttat tattaatcgt tccaccgaat cctgttaagc tacccgtttt
    11701 accgacaaca cgatgacatg gcacgataat tgataatgga ttacttccga ctgcacctcc
    11761 aaccgcttga gctgacattt ttggcttatc aagcaccttg cctacttttt tggcaatagc
    11821 accatacgtt gttaacgtcc cataaggaat ctgtcttaat tcattccaaa cacactgttg
    11881 aaaatcacta cctgttggct ttaaaggtat tgtgatttca ggattgtcac ctttaaaata
    11941 cgcgtctaac cactgtgtcg cctctttaaa tatcgctaaa gacgtatttt cttccctatt
    12001 accatcacct tgttgatttt caaacaaaac agcggtcaga cttaccccat cactcaaaag
    12061 ttccaatcgt ccaacaggag aatcatagta actcttatat accataaaca cacactcctt
    12121 ttgcatcatc atactattca tttaacttta tgaaaatgat taacacttta tgctttatca
    12181 agatcaacta ttcacttcca aatcaaaatt cacacagact tccaacacaa tataccattt
    12241 cttaattaac tatgtatcaa cacatacatt tcttaaccat tgattaatat ttacttttaa
    12301 attcttactt acttcaaaaa ttacacaaaa agttcataaa gtgcctacaa tgcgccgttt
    12361 ttaaaactac aatggtggaa aaatagaatt gccattgttt atagtttgca tatagtttca
    12421 atgtattttc ttttacttat tagtttaaaa atttagaggt gatgtttatg aataacaatt
    12481 ttttcaatag tgacttcgat tctattttac gaagaatgat gcaagacatg caaagctcaa
    12541 atcagactag taacaagaaa tactatatta atggtaaaga agtttcaccg gaagaattag
    12601 cacaatttac gcaacagggt ggtaatcatt ctgccgaaca aagtgcgcaa gcttttcaac
    12661 aagcagcact aagacaacaa ggtcaacaag gtggcaatgg caattattta gaacaaattg
    12721 gtcgcaatct tacgcaagag gctcgtgacg gattattaga tccagtcatc ggtcgtgata
    12781 aagaaatcca agagactgca gaagtcttaa gtagacgcac taaaaacaat cctatcctag
    12841 tcggagaagc tggggttggt aaaactgcga ttgtcgaagg tttagcgcaa gcaatcgttg
    12901 aagggaacgt acctgcagca atcaaagata aagaaattat atctatagat atttcatcgc
    12961 ttgaagctgg aacgcaatat cgtggcgcct ttgaagaaaa catccaaaag ttagttgaag
    13021 gcgttaaatc atcacaaaat gctgtgctct tctttgacga aattcaccaa atcatcggtt
    13081 ccggtgcaac tggaagtgat tccggtagta aagggttatc tgatatttta aaaccagcat
    13141 taagtcgtgg tgaaatttca attataggtg caacgactca agatgaatat cgaaacaata
    13201 ttcttaaaga tgctgcatta acgcgcagat ttaatgaagt acttgttaat gaaccaagtg
    13261 ctaaagatac tgttgaaatt ttaaaaggta ttcgcgaaaa attcgaagaa caccatcaag
    13321 taaaattacc agatgacgta ttaaaagcat gtgttgactt atcaattcaa tatattccac
    13381 aacgattatt accagataaa gcaatcgatg tgttagatat tacagcagca catttatctg
    13441 cacaaagccc tgctattgat aaagtcgcga ctgaaaaacg tatttctgaa ttggaacatg
    13501 ataagcgtaa agcggtaagt gctgaagaat ataaaaaagc tgacgacatt caaaatgaaa
    13561 tcaaatcatt acaagataaa ttagaaaata gtaatggtga acatactgcc gttgctactg
    13621 ttcatgatat ttcagatact attcaacgat taactggtat tccagtttct caaatggatg
    13681 ataacgatat tgaacgttta aaaaatattt ctaatcgttt aagaagtaaa atcataggtc
    13741 aagatcaagc tgtagaaatg gtttctcgtg caattcgccg taatcgtgct gggtttgatg
    13801 acggcaaccg tccaattggc agtttcctat ttgttggccc tactggtgtt ggtaaaacag
    13861 agcttgctaa acaattagca attgatctat ttggtaataa agatgcactg attcgacttg
    13921 atatgagtga atatagtgac acaacagctg tttcaaaaat gattggtaca actgctggtt
    13981 atgtcggtta tgatgacaat tcaaatacgt taactgaaaa agtacgccgt aatccatatt
    14041 cagtcattct atttgatgaa atcgaaaaag caaatccaca aattttaaca ttgttattac
    14101 aagtaatgga tgatggtaat ttgactgatg gtcaaggtaa tgtcatcaac tttaaaaata
    14161 caattattat ttgtacatca aatgctggct ttggtaacgg tacagaccaa gaatacgatg
    14221 acattatgca tgaaatgaaa aaattcttcc gccctgaatt ccttaaccgc ttcaacggta
    14281 tcgttgaatt cttacattta gataaagatg cattacaaga tatcgtcaac ttattattag
    14341 acgatgtcca agtaacatta gataaaaaag gtattacgat gaatgtctct caagatgcaa
    14401 aagattggtt aattgaagaa ggttatgatg aagacttagg cgcacgccca ttaagacgta
    14461 ttgttgaaca gcaagtacgt gacaaaatta cagattacta tttagatcat actgacgtta
    14521 aacatgtgga tttagatatc gaggacaatg aattagtcgt caaaggtaaa tcatgatact
    14581 ttaacatatt gcgtatcaaa aaatgagcat caggacgccc tcacctgtgc tcatttttta
    14641 aattatttcc caggaaaatg attcgctgtg tgctgttctg ttccacaaca atcacgatca
    14701 atgtcacatg taccacattt tccttgtttc gaacgtttga aaaatttaac taacgtatac
    14761 aaggcatatc cgaaaattgc taaaaaaatt aaaatgttaa taatgactga cactttaacc
    14821 actccttaaa caaataaatg tccgacttga taaaaaatga atgttaagac atatgcagtg
    14881 actagaggat aggcaactgc aagtgccgtc catttccatg aataagtctc tttacggatt
    14941 gctgccactg tagaaacaca aggaatatac aatagtataa atatcataaa tgcatacgca
    15001 gatagcggtg tgaattgatt ttgaatcaca ttaacaaggc ctgcatcacc tgatgaatag
    15061 ataatcgcca tcgaacttac gataacttct tttgctaaaa atcctggcac taacgtagca
    15121 cctgcttgcc atgttccaaa tccgagcggt tgcactaaca taccaaagaa gctaccaacc
    15181 atatgtaaaa aactttgatt gatattcaca ttgataccat gtggtcctac ataacttaat
    15241 agccaaatga ctactgagcc gccaaaaata aatgtacctg ctttacgaac aaagccctta
    15301 gccttttccc aagtactacg ccacaacgtt ttaatggaag gcacacggta tgttggcaat
    15361 tccacaataa agattgcatt atcatttttc aaaaccgttt tagtaagtac tgtactgact
    15421 aaaaatgcca taataatacc taaaacatac aagcttaata ctactaaaga ttgattctct
    15481 ttgaaaaaga tacctacgaa caacgcatac actggcagtc tagcagagca tgacatgaat
    15541 ggtgcaatta atatcgttgt taaacgctct ttttcatttt caatactgcg cgcagccata
    15601 atactcggta cgttacaacc aaatccgata atcatcggta taaaagactt cccgcttaaa
    15661 ccgaacgatt ccataatacg atccattaaa accgcaatac gtgccatata acctgaatct
    15721 tctaataaag atataaagaa aaagagcaca acaatttgtg gtacaaagac taatactgat
    15781 cctacaccag caataatgcc atctgtaatt aaatcttgta aaaatggtat aacgccaaga
    15841 taattcataa tcgtcttcac actatccgta aatgtaccac ctataaatgc atcgagttga
    15901 tccgacaaag gtgtgccaat ccatgtaaat gtagtttgaa agatcaacca cataatcgct
    15961 agaaagatag gcatccctat atatttatgt gttaatatct tgtctattct agagctgaaa
    16021 tattgcttat cttcatctgg atacgttacc acgtcttgca ataacgtctc aatataatga
    16081 ttgcgtatac gctccatctc tcgacgaaca gatacagctt ctacttgttt agcaacttga
    16141 tcacgtaaac tcgacaattt atttacaacc tctgaattaa gttcgtttgc aatttgcatg
    16201 ttatttaata agaattgaat cgcaataaat ctagcttgat atttatcatg agatgtctct
    16261 gtcattatta tttgacacat atttttaatt gtctcttcaa tcttctcacc ataattgatt
    16321 ttaaaatgcg gttgataccc ttcccctaga tgctttattt cgccaagtaa atgtttagtt
    16381 cctttgcctg tacgtgccac aactggaaaa ataggtgttt ttaacttttt catcaattta
    16441 tgataatcga tttttatccc gcgctttgtt gctacatcaa tcatatttaa tccgatgtat
    16501 attggttgat taagttctaa caattgtact gttaattgca tatttctttt tagttgactc
    16561 gcatcaacaa tgttaatgat tcctgaaaat gaatcgttta ataaatagtc tgtcactaca
    16621 gtttcatctt tagaaatcgg cgataaatca tatgtacctg gtaaatcaat taattgtcct
    16681 acattttctt taagctttcc tacttttttc tctaccgtta cgccactcca gttgcctata
    16741 tattcatacg aaccagttaa agcgttaaac aaagatgttt taccaacatt aggatttcct
    16801 aaaatacaat aattttccat tcgtccggct cctattcttc taatgcaata gaacaagcat
    16861 cgcaatgtct aatacttaac tgttgtccgt ttacttcaat aatacatggc cctttaaata
    16921 aacatttttg tttaatcgtt atgatagcgt catctgttaa cccaaaggca cttagacgat
    16981 acaacatatt ctcattagca atatccattc gctttatttt ataagcctta ttcatttcac
    17041 catttttaat gtttaacata ctatttcgct ctcctattag aaataataat cattatcact
    17101 taaaaatcat aacccttaaa attgtagctc gcaatacttt atttaaataa ttttcatttt
    17161 tcatataaaa tttgtgacat tacaaaaatg ttttatataa tctcttacat gcaaaaaacc
    17221 tccacttcaa atatcattga tagacattta aagcggaggc atgtacatgt tattttatga
    17281 tttatttctt aagttttttt ctaacaattg attgagcttt tcaatatttt tattcaactg
    17341 ttctatgttc gttacttgtt gttttgaatt tagttgatgc ttgttttgat aatcaattaa
    17401 agcatcatat aagaacaatg aacttgctga ttgctgtttc acttcttggt acaatgccat
    17461 cgttttatca tctagtacta ttgaatgtgc atcatcttgc ccatgtacat cttgatattt
    17521 cgatacattt gttgcacctt gtggatatac tttaaaggtt gtgtcgtatg tttccttact
    17581 atctttagct tcagattcct gtgattcaac cgttttatat ttttcaagtg catgtccttc
    17641 aatatcaact cgtggaataa tgcgattcaa ccatgctggt aaataccacg aaccttttcc
    17701 aaacaattta gttaatgcag gaattaacat cattctgact acgaaggcat caaagagtac
    17761 accaaacgct aatgccatac ccattgattt aatcatgaca tcttcttgga atacaaacgc
    17821 aaagaagaca ctaaacatga ttaatgcagc tgctacaata acaggaccac tttctttcaa
    17881 tcctactttg atagaataat cattatcccc tgttttacta tattcttcat gaattcgcga
    17941 cataaggaag acttcgtaat ccattgctaa gccgaatagt ataccaattg taataaccgg
    18001 caagaaggct agaattggtc ctgtcgtttc tatgccgaat aatcctttca taaaaccatc
    18061 ttgcattact aatgttgtaa atcctagcgt tgccattaat gacaagacaa atcctaaaac
    18121 tgcttttaac ggtattagaa ttgaacggaa gacaatcatt aataagaaaa atgccaatac
    18181 aacaatgact gttgcaaata aaggtatcgc ctcatttaac tttttagaca tatcgatatt
    18241 aatgacactt tgtcccgaaa tctccgtttt gaacccatat ttatcttgtg catctctatg
    18301 ataatctcgt aaatcatgca ctaaatcatt tgtgctctct gcattaggcc cttgcttagg
    18361 tatcacgacc atcaaagcat aatcattatc tttactcatt tgtggcggcg taacgatatc
    18421 tacatttttc ttatctttaa tatctttata cacagattgt aaatcttgtt gtaatccttg
    18481 tggatcatcc tttttatctt tcacatttat caacatcgga atttggccat taaatccttc
    18541 accaaattta tccgagataa tatcgtaagc ttttttctgt gtagaatctg ctggtttaac
    18601 accgtcatct ggaataccaa gtcgcatatg actaactggt attgcagctg ctactaatat
    18661 gattaaacct agtaatactg ccgcaagtgc atttcctgta ataaatttag accatggcgt
    18721 atcaatatct tttttgaatt tagactgtaa tttattcact ttaatgcgtt tatggaaaat
    18781 gcttattaat gcaggtaata aagttaaagc gctaagtact gcaaaaacaa cactaattgc
    18841 cgaagcaaat cccattaccg ctaagaagtc aatacctact aatgataaac cacatactgc
    18901 aatcacaact gtcacaccag cgaagatgac tgcgctacct gctgttccca ctgcaagtcc
    18961 gataccttta acatagtctg tttcagtttt cattacttgt cgatatctaa acaaaataaa
    19021 taatgcataa tcgataccaa cagcgagccc aatcattacc gctaatgtca gtgtgacatt
    19081 tggtatatca aatgcataag ttaacaagct gataatgcca accccagatg ctaaaccaat
    19141 caatgcactt ataattggta atcctgcagc aatgactgaa ccaaatgtaa tcaataacac
    19201 tacaaatgca acaatgatac caactagttc agaattaccg cctacttctg tagatgtcat
    19261 tcctgtacca gttaactctg tttgtacatt atgattgtca cgtaagtctt tcaaatgact
    19321 tttaacatta tctctagagc catcttttaa agatgtttga ctaacgtcat atgtgatatc
    19381 tgcaaatgct gttgttttat ctttactaat ttgcttattt tcataaggat ctgatatttt
    19441 atcaatgtgc ttgtcatctt ttttaatatc atctaacgtt ttcttaatat ctttagtaat
    19501 gttcggttgc acaataccat catctttagt cgtcttaaag acaacacgta tttgtgcctt
    19561 ttcactatct tgattaaaat gtttttcaat ctttttattc gtatctaacg actctaatcc
    19621 tgtcatttta atatcattgt caaatttcgg tgcatttgta gcaagtggta tcaatattgc
    19681 agctacaatc actatccatg caatgaccgc ggaccattta tgttttgcga tgaatgtccc
    19741 catcttatat aaaaattttg ccaaagtata ttgcctcctt ttaaaatcaa cgttatagtt
    19801 taactataca gtgtagatta ttgtttgatt atagtatcta tccccgacct cttaaagaat
    19861 caattggaaa attttgtata ttaaactaca cacaaaggag aaatgtagat gaaagagact
    19921 gatttacgag ttataaagac aaaaaaagca ttgtcaagta gcttgctgca attgttagaa
    19981 cagcaattat tccaaacgat tactgtcaat caaatttgcg acaacgcact cgtacaccgc
    20041 acaacatttt ataaacattt ttatgataaa tatgatcttc ttgaatattt atttaatcaa
    20101 ttgactaaag actatttcgc cagagacatt agcgatcgtc ttaaccaccc atttcaaacg
    20161 attagcgata caattaacaa taaagaagat ttgcgagata ttgcagaatt tcaagaagaa
    20221 gacgctgaat ttaataaagt attaaaaaat gtctgcatta aaattatgca taacgatatc
    20281 aaaaataata gagaccgtat cgatattgac agccacatcc cagataatct catattttat
    20341 atttatgact cgttgattga aggttttatg cattggataa aagatgaaaa aattgactgg
    20401 cctggtgaag aaattgataa aattttccat aagataataa atattaagat taaatagtag
    20461 atgagaggct cataagcgtc accagcattc ataataaaaa cgatagttta cacattaatg
    20521 cattcgtgta ctactatcgt tttttatttt tatcgtgctt atcgctatta aaataactga
    20581 tacacaacac ataaactatg aagaaaaaaa taaatccgct atctaaatga ctttgactca
    20641 gttgtttcaa tgaccaaatt gctaatacaa ttgccatgat tattgaaata acgtatctca
    20701 tattcttata cctatcatcc ttttctaaaa atatggttgc tattacttaa tttttaaagt
    20761 tataaataaa aagagccaac cgcaatggat ggcccttgtt cattatgaag cattagaaca
    20821 tttctgaaac aaccttttgt tctaagaagt gtaataagta gtctgggcta cctgttttag
    20881 cgtcagtacc tgacattttg aaaccaccaa atggatggta tccaacaact gctgaagtac
    20941 agcctctgtt aaggtataaa ttacctacat caaattcgtt taccgcttta atccaatgct
    21001 cgcgattatt tgtaatcact gcaccagtta aaccgtaatc tgtatcattt gcaacctcaa
    21061 ttgcttcatc aaaatcgtta actttcacaa agccaacaac tggaccaaaa atttcttctt
    21121 gcatgattct atctttagat ttaagtcctg aaatgattgt tggttctaca aagtaacctt
    21181 ttgaatcatc agtgccgcca ccttgttcta atttaccttc ttctttacca atctcaatat
    21241 aatttttaat cttatcaaat tgttttttat taataactgg gcccatatac gtattgtcta
    21301 cagtattgcc caacgttaat tcttttgtta atttgattga tttctctaat acttcgtcat
    21361 aaacgtcttt atgcacaatt gcacgtgaac atgcagaaca tttttgacca gagaaaccaa
    21421 acgctgacgt tacaatagct tctgccgcca tatctgtatc aatattttca tcaactacaa
    21481 tggcatcttt accacccatt tcagcgataa cacgtttcaa gaagttttga ccttcttgaa
    21541 ctacggcact acgttcataa attctagtac ctgtcgcacg tgatcctgta aatgtaacga
    21601 aatgcgtatc tttatgatca actaagtaat caccaatttc tttcggatca ccaggaacaa
    21661 agttaactac gccttttggt aatcctgctt cttctaaaat ttccattaat ttataagcga
    21721 tataaggtgt atcctcagca ggtttcaata acactgtatt acctgccaca actggtgcta
    21781 aagttgtacc agccataatc gcaaacggga agttccacgg cggaattgta acacctgtac
    21841 caattgattt atagaaatat ttattgtgtt caccttcacg atcaagtact ggcttgcctt
    21901 gagccaagtc catcattgaa cgtgcatagt attcaataaa atcaatacct tcagctgcat
    21961 caccaactgc ttcatcccat ggcttacctg cttcataaac cataattgct gcaatttccg
    22021 cttttcgacg acgaataatt gccgaaacac gtaacataag ctctgcacga tcatttgctg
    22081 accatgtttt ccaagattta taagcttcgt ttgctgcttt aaatgcatct tcaacatctt
    22141 gttttgttgc ctttgatgca tttgcaatta cttgtgatgt gtctgcagga ttgattgatt
    22201 taattttgtc atctttgaaa atcttctctc cattaatcac taatggtatg tcttgaccta
    22261 attctttttc cacgtctttc aatgctttct taaacatatc cacattttct tggactgaaa
    22321 aatcgtaacc aggttcattt ttaaattcta ctaccatgta cacttacccc ctataaattt
    22381 tgaaagtggt ttaacccttt gatttaatga tataacatca tttaaactca ttttactatg
    22441 attaaggtca gttttgcaat cgctttcatt tttatgcttt atccctcatt ctcaagcatt
    22501 ttgaaattga ttggttactt tttaaaattt atatgtgtcg caactactac tttatcgttt
    22561 cgtcatttaa tgtttcggat ggtaggtcat tatcaatttt acgaacgact ttacaagggt
    22621 ttccaaccgc taagctgtgt ggcggaatat ctttagtgac aacactacca gcaccaatca
    22681 cactaccttc tccaatcgtc acccctggta gcacggctac atgaccgcca aaccaagtat
    22741 tactgccaat atgaatgggt ccggcttttt caaaaccttc atttctatga tgaaaattaa
    22801 gtggatgtgt cgctgtgtag aatccacaat taggtccaat aaaaacatta tcgccaattg
    22861 taatctgtcc accatccata aaataacaat tggtgtttac atagacattt tttcctagtt
    22921 taacgttcca accataatct gtatcaaaag gaatcgaaat acttacatta tctgttgttg
    22981 tttgaaataa ttgatcgatt aattcctttc ttttaattgt gtcactcggt cttgtatgat
    23041 ttaattcaaa gcaaatatct ttcgctcgtg cacgttcatt gattaagtct tgatcaaagt
    23101 ttgcatcgta ccatttttct gctaacattt tttctttttc agtcattaca cctttcaact
    23161 cctaataact tatttacttg tttaaaagtt aatcaaataa acattcgcct atgcaactaa
    23221 tacgctataa cattatgaaa tcgtgacctt atcaccctta tctatacaat tctcgcatca
    23281 aatactgcta aagtagtaga taaattcaat actacagacg cattcatttt ttaatctatt
    23341 aacgtacaat gtgagtaaga gaaatataaa ggagtatgat agcgatgaga atattaatta
    23401 caggcacagt tgctatctta atcattctag gtttagttaa aacgatacaa gattacgaaa
    23461 tgacaaacga cacaagtcgt cagatgtcag acaacaaaga tgatgataaa gtcatccatc
    23521 ttaataattt taaaaattta catgcgaaag aatttaaccc atctgatttc ttttaagtca
    23581 cctaagaatt gcaaatccag aagtcattta agttttacct ttcattcata catcctttaa
    23641 tattaattac gacttctttt atatagatgc taaatagaga gattgttgtg caatgtttgc
    23701 acggcaatct ctctttttct ttttaaaatt ggtaaaagta aaacgcaacg attgacttat
    23761 atacctatag ggggtacatt agacgtgtaa caatgaatca cagggaggca ataatgtggc
    23821 taatacgaaa aaaacaacat tagatatcac tggtatgact tgtgccgcat gttcaaatcg
    23881 tatcgaaaag aaactgaata aacttgatga cgttaatgcc caagtgaatt taactacaga
    23941 gaaagcaact gttgagtata accctgatca acatgatgtc caagaattta ttaatacgat
    24001 tcaacattta ggttacggtg tcgctgtaga aactgtcgaa ttagacatta caggtatgac
    24061 ttgtgctgca tgctcaagcc gtattgaaaa agtgttaaat aaaatggacg gtgttcaaaa
    24121 tgcaactgtc aatttaacaa cagagcaagc taaagttgac tattatcctg aagaaacaga
    24181 tgctgataaa cttgtcactc gcattcaaaa attaggttat gacgcgtcta ttaaagataa
    24241 caataaagat caaacgtcac gcaaagctga agcgctacaa cataaattga ttaagcttat
    24301 catatcagca atattatctt taccactatt aatgttaatg tttgtgcatc ttttcaatat
    24361 gcatatacca gcactattta cgaatccatg gttccaattt attttagcta cacctgtaca
    24421 atttattatt ggatggcaat tttatgtagg tgcttataaa aacttaagaa atggtggcgc
    24481 caatatggat gtacttgttg ctgttggtac aagtgcagca tatttttaca gtatttatga
    24541 aatggttcgt tggctaaatg gctcaacaac gcaaccgcat ttatactttg aaacaagcgc
    24601 cgtactaatt accttaatct tattcggtaa gtatttagaa gctagagcga agtctcaaac
    24661 aaccaatgcg cttggcgaat tattaagttt gcaagctaaa gaagcacgca ttttaaaaga
    24721 tggtaatgaa gtgatgattc ctctaaatga agtacatgtt ggagatacac ttatcgttaa
    24781 accaggtgaa aagatacctg ttgatggtaa aattattaaa ggtatgactg ccatcgacga
    24841 atctatgtta acaggtgaat ctatacctgt tgagaagaat gttgatgata ctgtaattgg
    24901 ttcaacgatg aacaaaaacg gtactattac tatgacagca acaaaagttg gcggggacac
    24961 tgcgttggca aatattatta aagttgtcga agaagctcaa agttctaaag cgccgattca
    25021 acgattggca gatattattt ctggttattt cgttcctatc gttgttggta tcgcactatt
    25081 aacatttatc gtgtggatta ctttagttac acctggtaca tttgaacctg cacttgttgc
    25141 gagtatttcc gttctcgtca ttgcttgccc atgcgcatta ggacttgcta caccaacttc
    25201 tattatggta ggtactggtc gcgctgctga aaatggtatt ttatttaaag gtggcgagtt
    25261 tgttgaacgc acacatctaa ttgataccat cgttttagat aagacgggta ccattacaaa
    25321 tggtcgtcca gtcgtgacag attatcatgg tgacaatcaa acgctacaac tactcgctac
    25381 tgctgaaaaa gattctgaac acccattggc agaagccatt gtcaattatg caaaagaaaa
    25441 gcaattaaca ttaactgaga caacaacatt taaagcagta cctggccatg gtattgaagc
    25501 aacgattgat catcaccata tattggttgg taaccgtaaa ttaatggctg acaatgatat
    25561 tagcttgcct aagcatattt ctgatgattt aacacattat gaacgagatg gcaaaacagc
    25621 tatgctcatt gctgttaatt attcattaac tggtatcatc gcagtggcag atactgtcaa
    25681 agatcatgcc aaagatgcta taaaacaatt gcatgatatg ggcattgaag ttgccatgtt
    25741 aactggcgat aataaaaaca ctgctcaagc cattgcaaaa caagtaggca tagatactgt
    25801 tattgcagat attttaccag aagaaaaagc tgcacaaatt gcgaaactac agcaacaagg
    25861 taagaaggtt gcaatggttg gtgacggtgt aaatgatgca cctgcattag ttaaagctga
    25921 tatcggtatc gccattggta caggtacaga agttgccatt gaagcggctg atattactat
    25981 tcttggtggc gacttgatgc ttattcctaa agccatttat gcaagtaaag caaccattcg
    26041 taatattcgt caaaatctat tttgggcatt cggctataat attgccggta tccctatagc
    26101 tgcattgggc ttacttgcgc catgggttgc tggtgctgca atggcactaa gttcagtaag
    26161 tgttgtcaca aacgcactta gattgaaaaa gatgcgatta gaaccacgcc gtaaagatgc
    26221 ctagattcct taataatgaa ggattcgttg gtgattctga ggtagactag tgattggctc
    26281 tataatgtcg cggtttacag ttggatcttc gctcctactg catatatagt tacacttttc
    26341 gcttggcgaa ttagtgtgtc ttacctaata gctccgccta ttaggttcca a
//
LOCUS       DAPSKH010000038        25927 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPSKH010000038 DAPSKH010000000
VERSION     DAPSKH010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 25927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25927
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.038"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..556
                     /locus_tag="RPH49_001664"
     CDS             <1..556
                     /locus_tag="RPH49_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDY5124808.1"
                     /translation="VKPCIAGRPRTKGKVESIMKILDEIHAYQGELYLEEIPKFISNL
                     NERLNYSVHTSTGKIPIIALEKEKSFLQPLPNVNVRNSYKVKHKYLKVNRSNMITYKS
                     NQYSVPAEYCGKIVEVQVYDQKLHVYYNTKSICEHLITQRKLNYQKEHYLETLSSSFG
                     NREMDDINQIAIDNLNAIGELYDE"
     gene            549..1310
                     /gene="istB"
                     /locus_tag="RPH49_001665"
     CDS             549..1310
                     /gene="istB"
                     /locus_tag="RPH49_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDY5124809.1"
                     /translation="MNNSTNYKRLKANLEYLKMNQMINHLDDVIDFSIKNNLSFIDTL
                     IKLSDYEIEIKEKNLIESMVKVAAFPFKKEISDFDFNFQPSINQQEIWDFTDLRFIEK
                     YQNIVFLGSSGVGKTHLATGIGMAAAKNRVSTYFIKCHHLIENLRKAKLENRLENRLK
                     HYSKYKLLIIDEIGYLPIGSEDAKLFFQLIDLRYEKKSTIFTTNINFNLWNEIFDDPK
                     IANAILDRILHHSSVVKIKGKSYRLKDHSPKKEIT"
     gene            1337..1417
                     /locus_tag="RPH49_001666"
     CDS             1337..1417
                     /locus_tag="RPH49_001666"
                     /inference="COORDINATES: protein motif:HMM:NF018593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 family protein"
                     /protein_id="HDY5124810.1"
                     /translation="MIYVHFYIDIYSIATFIFYKEYFYEE"
     gene            1506..1823
                     /locus_tag="RPH49_001667"
     CDS             1506..1823
                     /locus_tag="RPH49_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124811.1"
                     /translation="MAENIKTEQHYYTKDFSGYRNEEDNFVANQELTVTITLNEYRKL
                     IEIKAVKDKEEDTYRGKYFAEERKNEKLEKENIKLKNKIYELQNEEDNEECEEEYEEY
                     KED"
     gene            1828..2088
                     /locus_tag="RPH49_001668"
     CDS             1828..2088
                     /locus_tag="RPH49_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1108 family protein"
                     /protein_id="HDY5124812.1"
                     /translation="MYYKAGEIKNKIINFNGFEFKVSAMKRHDGISIQVKDMNNVPLK
                     SFHVVDLSELYIAMDAMHDVINEWIEENTDEQDRLINLVMKW"
     gene            2098..2319
                     /locus_tag="RPH49_001669"
     CDS             2098..2319
                     /locus_tag="RPH49_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2483 family protein"
                     /protein_id="HDY5124813.1"
                     /translation="MKQTVTYIIRHRDMPIYITNKPTDNNSDISYSTNRNRAREFNGM
                     EEASINMDYHKAIKKTVTETIEYEEVEHD"
     gene            2312..3091
                     /locus_tag="RPH49_001670"
     CDS             2312..3091
                     /locus_tag="RPH49_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDY5124814.1"
                     /translation="MTEQTNQDVDILTQLGVKDISKQNANKFYKFAIYGKFGTGKTTF
                     LTKDNNALVLDINEDGTTVTEDGAVVQIKNYKHFSAVIKMLPKIIEQLRENGKQIDVV
                     VIETIQKLSDITMDDIMDGKSKKPTFNDWGECATRIVSIYRYISKLQEHYQFHLAISG
                     HEGINKDKDDEGSTINPTITIEAQDQIKKAVISQSDVLARMTIEEHEQDGEKTYQYVL
                     NAEPSNLFETKIRHSSNIKINNKRFINPSINDVVQAIRNGN"
     gene            3121..3675
                     /locus_tag="RPH49_001671"
     CDS             3121..3675
                     /locus_tag="RPH49_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDY5124815.1"
                     /translation="MKITGRTQYIQETNQEAFMKGGDFLGAGEFTVKVANVEFNDREN
                     RYFTIVFENNEGKQYKHNQFVPPFQQDYQEKQYIELLSRLGIKLNLPDLTFDTDQLIN
                     KIGTIVLKNKFNEEQGKYFVRLSYVKVWNKDDEVVNKPEPKTDEMKQKEQQANGKQTP
                     MSQQSNPFANANGPIEINDDDLPF"
     gene            3688..4359
                     /locus_tag="RPH49_001672"
     CDS             3688..4359
                     /locus_tag="RPH49_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124816.1"
                     /translation="MQYITRYQKDNDGTYSVVATGVELEQSHIDLLENGYPLKAEVEV
                     PDNKKLSIEQRKKIFAMCRDIELHWGEPVESTRKLLQTELEIMKGYEEISLRDCSMKV
                     ARELIELIIAFMFHHQIPMSVETSKLLSEDKALLYWATINRNCVICGKPHADLAHYEA
                     VGRGMNRNKMNHYDKHVLALCREHHNEQHAIGVKSFDDKYHLHDSWIKVDERLNKMLK
                     GEKKE"
     gene            4356..4505
                     /locus_tag="RPH49_001673"
     CDS             4356..4505
                     /locus_tag="RPH49_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124817.1"
                     /translation="MNRLRIIKIALLIVILAEEIRSAKKIKKFTPEDSKGFPDITKDS
                     IKEPK"
     gene            complement(4498..4779)
                     /locus_tag="RPH49_001674"
     CDS             complement(4498..4779)
                     /locus_tag="RPH49_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124818.1"
                     /translation="MEKPYMLTYDLNSPGQKYEELRNVIKKEISNGHCNYWKSSFLFR
                     SSLSTSEMIEKLKPYLDSGDKLFVTEIVNNKQGWLTKEQWDFINHNIFI"
     gene            4906..5313
                     /locus_tag="RPH49_001675"
     CDS             4906..5313
                     /locus_tag="RPH49_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDY5124819.1"
                     /translation="MSKPKWNSAKKRKIKNELTQGIYKCVMCSNIFDSVDCLQIEHKI
                     PISKGGTNEMSNLTVLCQKCNCSRKNRVGNEHLKNILKNIEKEMDKINIDLLAYEKEI
                     GTLDNRDISEIINELESIYTDFHNTLVGEVLNV"
     gene            5306..6028
                     /locus_tag="RPH49_001676"
     CDS             5306..6028
                     /locus_tag="RPH49_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5124820.1"
                     /translation="MSKDKIKNSITGYGLVFKRVMKDTTISIEAKALYSYLSSYAGVD
                     ETAFPSVDLIKHELAIGKQRYQRARKELETAGYLQVDRKQNGNIYGSNLYTIYHSPRW
                     VDSRPVEIQSVEIQSLDNQPTTINSITNNNYTNNNKTINNSATDVTHEQFEEWWKLYD
                     KKKDKKISFTKFKSCLKKHSFEQIMQGTREYLKTITDKQYQKYPKTFLTNESYMNDYS
                     EEIKETGIDQLERMKYDESYWD"
     gene            6038..6811
                     /locus_tag="RPH49_001677"
     CDS             6038..6811
                     /locus_tag="RPH49_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDY5124821.1"
                     /translation="MKPLFNEKINESLKKYQPIEVILRQNCDKCGRQYDLYKFENGYE
                     YKDGCECEIQRLAYEEYKRNKQKKLDYIFNQSNVNPSLRDATVNNYKPQNEKQVQAKQ
                     TAIEYVQGFSTKEPKSLILQGSYGTGKSHLAYAIAKAVKAKGHTVAFMHIPMLMDRIK
                     ATYNKNAVETTDELVRLLSDIDLLVLDDMGVENTEHTLNKLFSIVDNRVGKNNIFTTN
                     FSDKELNQNMNWQRINSRMKKRARKVRVIGDDFRERDAW"
     gene            6805..6966
                     /locus_tag="RPH49_001678"
     CDS             6805..6966
                     /locus_tag="RPH49_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124822.1"
                     /translation="MVITKQNIKEILHCRDVYAQKMIDFANGDQEKLKKLIDDKLKEK
                     EERPAIVEY"
     gene            6979..7200
                     /locus_tag="RPH49_001679"
     CDS             6979..7200
                     /locus_tag="RPH49_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3269 family protein"
                     /protein_id="HDY5124823.1"
                     /translation="MPKEKYYLYREDGTEDIKVIKHEDNENEVYSLTGAHFSDEKKIM
                     TDSDLKRFKGAHGLLYEQELGLQATIFDI"
     gene            7211..7615
                     /locus_tag="RPH49_001680"
     CDS             7211..7615
                     /locus_tag="RPH49_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HDY5124824.1"
                     /translation="MSKYNAKKVEYKGIVFDSKVECEYYQYLESNMNGTNYDHIEIQP
                     KFELLPKLDKQRKIEYIADFALYLDDKLIEVIDIKGMPTEVAKLKAKIFRHKYRNIKL
                     NWICKAPKYTGKTWITYEELIKARRERKREMK"
     gene            7620..7805
                     /locus_tag="RPH49_001681"
     CDS             7620..7805
                     /locus_tag="RPH49_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001187261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3113 family protein"
                     /protein_id="HDY5124825.1"
                     /translation="MQQQAYINATIDIRIPTEVEYKHFGDVDKEKETLADYLYNNPNE
                     ILEYDNLKIRNVNVEVE"
     gene            7806..8177
                     /locus_tag="RPH49_001682"
     CDS             7806..8177
                     /locus_tag="RPH49_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124826.1"
                     /translation="MAKTARIVRIHDKPYRFSKFEMELIESHGITPGMVSKRVKDGWE
                     LHEAMDAPEGMRLSEYREKETIERLEQARLERKLERQRKKEAELRRKKPHLFNVPQKH
                     SRDPYWFDTTYNQMFKKWQEV"
     gene            8178..8426
                     /locus_tag="RPH49_001683"
     CDS             8178..8426
                     /locus_tag="RPH49_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phi PVL orf 51-like protein"
                     /protein_id="HDY5124827.1"
                     /translation="MPKTDSARKEYLNQFFGSKRYLYQDNERVAHIHVANGTYYFHGH
                     IVPGWQGVKKTFDTAEELETYIKQQDLEYEEQKQLTLF"
     gene            8435..8806
                     /locus_tag="RPH49_001684"
     CDS             8435..8806
                     /locus_tag="RPH49_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDY5124828.1"
                     /translation="MKVNYETGFQIGVMEARLKKMRKQRDEYKKQRDELIGDIAKLRE
                     RNEELENMWRTVKNELLGRYEHYCFKFRELHPESKANRIGALYIGGKSTADIIMSRME
                     ELDGTNEFYEFLGQMEEDTNE"
     gene            8799..9047
                     /locus_tag="RPH49_001685"
     CDS             8799..9047
                     /locus_tag="RPH49_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1024 family protein"
                     /protein_id="HDY5124829.1"
                     /translation="MNNREQIEQSVISASAYNGNDTEGLLKEIEDVYKKAQAFDEILE
                     GLPNAMQDALKEDIGLDEAVGIMTGQVVYKYEEEQEND"
     gene            9040..9567
                     /locus_tag="RPH49_001686"
     CDS             9040..9567
                     /locus_tag="RPH49_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP pyrophosphatase"
                     /protein_id="HDY5124830.1"
                     /translation="MTNTLQVKLLSENARMPERNHKTDAGYDIFSAETVVLEPQEKAV
                     IKTDVAVSIPEGYVGLLTSRSGVSSKTHLVIETGKIDAGYHGNLGINIKNDAQVYLTT
                     NEQCFDIQGEMENSFVNNAKKKPFTINDYYEIYKGDKLAQLVIVPIWTPELKQVEEFE
                     SVSERGAKGFGSSGV"
     gene            9604..9840
                     /locus_tag="RPH49_001687"
     CDS             9604..9840
                     /locus_tag="RPH49_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020444716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1381 domain-containing protein"
                     /protein_id="HDY5124831.1"
                     /translation="MTQYLVTTFKDSTGRKHTHITRAKSNQRFTVVEAESKEEAKEKY
                     ESQNTPIVYYTNNSKVTLFERPSEEVLGSLFEKK"
     gene            9865..10101
                     /locus_tag="RPH49_001688"
     CDS             9865..10101
                     /locus_tag="RPH49_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124832.1"
                     /translation="MFNTPKMKLPEKHTEVFKTYKNGTPEEKAEIEGCFIKTVKDEDS
                     EFYSPMLASLNEQQLKSMLRQVLFLIDTGDDNDD"
     gene            10094..10243
                     /locus_tag="RPH49_001689"
     CDS             10094..10243
                     /locus_tag="RPH49_001689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDY5124833.1"
                     /translation="MIKQILRLIFLLAMYELGKYVTEQVYIMMTANDDVEVPSDYVFR
                     AEVSE"
     gene            10243..10443
                     /locus_tag="RPH49_001690"
     CDS             10243..10443
                     /locus_tag="RPH49_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1514 family protein"
                     /protein_id="HDY5124834.1"
                     /translation="MWITMTIVFAILLLVCISINSDRAREIQALRYMNDYLLDEVVKT
                     KGYNGLEEYRIELKRINNDIKK"
     gene            10466..10936
                     /locus_tag="RPH49_001691"
     CDS             10466..10936
                     /locus_tag="RPH49_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124835.1"
                     /translation="MYNRKEIREMIDNYKWMKNIIDSKVYDNESTSIAQYGYQSAMPK
                     AKGTTSNKVLVKVINKNKALRKYDYLIKKIAFIDEYEEYITNEKDYHILQMLKQRESH
                     NRIMSILDIGRDNFYSRVKDIVNILYNLQQETDSSDTSYSSDTSYSSDTSYSSD"
     gene            11051..11503
                     /locus_tag="RPH49_001692"
     CDS             11051..11503
                     /locus_tag="RPH49_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase
                     family protein"
                     /protein_id="HDY5124836.1"
                     /translation="MEISKYQEIATRTHNDELNLNESITCYGLGLTQSTGNVTDLIKQ
                     HMFCNVPIDKGIMINELSEALWNIANLTNVLGINLDEIAGHSVNTILMNKPNQTINLD
                     NGIKQGDKVLFQGSKYLVDGSIGNLLLISNDKDDRQVTVQDVKKVDKE"
     gene            11518..11861
                     /locus_tag="RPH49_001693"
                     /pseudo
     CDS             11518..11861
                     /locus_tag="RPH49_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500683.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            11991..12458
                     /locus_tag="RPH49_001694"
     CDS             11991..12458
                     /locus_tag="RPH49_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDY5124837.1"
                     /translation="MAGRPKKLLSNSNKNYTKEEIIEKERQEAQLNKFSKIDTEPPHF
                     LDEIAKQEYLRILPHMQELPISNLDKAQLAQYCSFYSDFVKASLILEREDLILEDDKG
                     NQKVNPAFNIKEKAGIRLQQTANTLGLTIDSRLRIMVPDEKEDDDPYMEFVSD"
     gene            12461..14155
                     /locus_tag="RPH49_001695"
     CDS             12461..14155
                     /locus_tag="RPH49_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HDY5124838.1"
                     /translation="MTDYVTKYAKKVVSGEILASLKNIQVCKRHLSFMENPPNGCHWD
                     NHLSNKAIKFVEMLPDPKTNQPMPLMEFQKFIVGSLYGWRRGQYRMFTKAYISMARKQ
                     GKSLIVSGMSVNELLFGQYPKFNRQIYVASSTYKQAQTIFKMASQQVNLMRSKSKFIR
                     EKTDVRKTDIEDVLSSSVFAPLSNNPDAVDGKDPTVAILDELASMPDDEMYSRFKTGM
                     TLQKNPLTLLVSTAGDNLNSQMYQEYKYIKRILNEEVRADNYFVYCAEMDSQEEVQDE
                     TKWIKAMPLLESKEHRKTILQNVKADIQDELEKGTSYHKILIKNFNLWQAQREDSLLD
                     ISDWEQVITPMPNINGKDVYIGVDLSRLDDLTSVGFIFPNDDKKVFLHSHSFIGLRTN
                     LEQKSKRDKINYELAIERGEAETTQSDSGMIDYKQVIDFIVKFITTHDLNVQAVCYDP
                     WNAQSFITTIESMALDWPLIEVGQSFKALSQSIKEFRMWVADERIQHNDNMLLTTSVN
                     NAVLIRDGEDNVKINKKMNRQKIDPIISIITAFTEARMHEFQENWTEKYESEEFGF"
     gene            14375..15625
                     /locus_tag="RPH49_001696"
                     /pseudo
     CDS             14375..15625
                     /locus_tag="RPH49_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511072.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            15618..16202
                     /locus_tag="RPH49_001697"
     CDS             15618..16202
                     /locus_tag="RPH49_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDY5124839.1"
                     /translation="MSKETRVGNIIEVRSNDNNEMVIEGYALKFDTWSENLGGFKETI
                     SRRALENTDLSDVRCLVDHIPSQIIGRTKSGTLELETDDVGLKYRCKLPNTTFARDLY
                     ENMRVGNINQCSFGFMLDDKGDEVRFDEQENIYKRTLTAIRELTDVSVVTYPAYKDTD
                     VKPALRSIETVKKEQRKKELEIRLKKHSILNNIW"
     gene            16290..17537
                     /locus_tag="RPH49_001698"
     CDS             16290..17537
                     /locus_tag="RPH49_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDY5124840.1"
                     /translation="MKTKEELQSEISDIKRQIDLKVKYATRALNNDELEKAEKLEQEI
                     TDLRSQIQEKQEELDKLKEKDGTSENNQQSVEVNEARTYRNQANINDLGISIQNTKVT
                     SQEVRDFTEYLETRNDIQGGSLKTDSGFVVIPEEIVTDILKLKEVEFNLDKYVTVKRV
                     TNGSGKYPVVRQSEVAALEKVEELEENPELAVKPFFQLAYDINTHRGYFRISREAIED
                     AKVNVLQELKLWMARTIAATRNKAIIDVITKGSTGSTSSGFEKEGKKLEVKKAKSLDD
                     IKDAINLNVKPNYEHNVAIVSQTMFAKLDKMKDKLGNYLIQPDVKEKTQQRLLGAKIE
                     ILPDEVLGQKGNNTLIIGNLKDAIVLFDRSQYQASWTDYMHFGECLMIAVRQDCRILD
                     YKSAIVIEYDDSERGEGDLGLEA"
     gene            17573..17731
                     /locus_tag="RPH49_001699"
     CDS             17573..17731
                     /locus_tag="RPH49_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124841.1"
                     /translation="MAMYEVKKSYTDLEKGQYLKSGKRVEMTVKRAEYVNKKLKEHGV
                     ILERVKEE"
     gene            17740..18072
                     /locus_tag="RPH49_001700"
     CDS             17740..18072
                     /locus_tag="RPH49_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HDY5124842.1"
                     /translation="MQLTAEELKLLKKHCKIDHNSEDDLLEIYYSWAFHEIASAVTDE
                     PSKYIDWFKSHPLFARAIYPLASYYFENRIAYLDRDLSLAPHMVLSTVHKLRGSFERF
                     LESENDEI"
     gene            18059..18394
                     /locus_tag="RPH49_001701"
     CDS             18059..18394
                     /locus_tag="RPH49_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail adaptor protein"
                     /protein_id="HDY5124843.1"
                     /translation="MMKFNSNKLNERIDFCEDVSERVNGNPMKPKTKILYSCFACIQE
                     SKESDTQTNLNTGSKFIKTIIIRDTRGDYKPTNKHYVLHEGQRFNIKYVKPDYQDKSY
                     LRIYGEVVI"
     gene            18394..18771
                     /locus_tag="RPH49_001702"
     CDS             18394..18771
                     /locus_tag="RPH49_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDY5124844.1"
                     /translation="MGARIESNNIEQGLKNAVLKMNLNSNVIVKAGAMSLVPLLKSNT
                     PFANTKKHARDHIAVSNVKTDRHTSEKIVTIGYAKGVSHRIHATEFGTMYQKPQLFIT
                     KTEKQGKNKVLKTMLDTAKRLQK"
     gene            18768..19148
                     /locus_tag="RPH49_001703"
     CDS             18768..19148
                     /locus_tag="RPH49_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124845.1"
                     /translation="MINVTELIRNAIIANNITDEVNVFNYTIDDHFHEKTDKPIIRIY
                     PLPFNPDTYADDNEISREYHYQIDVWWSQDEPNEQAEKIVELLKVINFQCYYREPLYE
                     SDVMSFRHIIRAKGSILSMKLEEN"
     gene            19149..20102
                     /locus_tag="RPH49_001704"
     CDS             19149..20102
                     /locus_tag="RPH49_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HDY5124846.1"
                     /translation="MIEKLKQAPRFLKLNLQHFADTGVSGIAIGVSNFYYAPILKDTE
                     NEWETGAGTRIRFLKEIEVDRPQDTEEDYGDDMVAATAVSNGKLSVKTTFVTVPADDK
                     AFLNGAKKGVGGYKYGAKDIPPDVAIVFERRNHDESSEWVGLFKGKFTRSSIKGQTKQ
                     DKVEFQNDDVEGNFIDRLFDESSHVTDYDKKGSTTGRDYVFMETFGKTYDEFMSSRGE
                     QNMEPVEKEMKKTEKVEVTSVNVTDEQVTVKVDATKQLSATTEPSGQKVTYAVTEGQT
                     YASVTSTGLVKGLAEGNATVTATAGKQTDTVQITVQSNLEM"
     gene            20167..20613
                     /locus_tag="RPH49_001705"
     CDS             20167..20613
                     /locus_tag="RPH49_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124847.1"
                     /translation="MERTSIELITGFTKTGKPQYQKYLAKPIITLFETIQGSKLGLKL
                     NKAFKGADFKDLTEEEFNNLSVTEQEEYKNKQEEYENNMAVQMEVLEEVLDFIVEAFD
                     NQFTSIELQKGLPNGQEGIEKIGQLIGRITGGEPSDTKKFVTENQK"
     gene            20673..20795
                     /locus_tag="RPH49_001706"
     CDS             20673..20795
                     /locus_tag="RPH49_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124848.1"
                     /translation="MIEKGMDAEKVANMPIHFFLDIVESKIETKRTAKSFKDIF"
     gene            20851..25503
                     /locus_tag="RPH49_001707"
     CDS             20851..25503
                     /locus_tag="RPH49_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDY5124849.1"
                     /translation="MPNPIGNMVIKVDLDGSGFNRGVTGLNRQMKMVSRELSANLSQF
                     SRYDNSLEKSKIKVEGLSKKQKVQAQITKELKDSYDKLSKETGENSAKTQAAAAKYNE
                     AYAKLNQYERELNQATQELKDMQREQKALNTAMGKLGTNFNNFGPKLQEIGNSMKNVG
                     RNMTMYVTAPVVAGFAVAAKKGIEFDDSMRKVKATSGATGEEFEALKKKAREMGATTK
                     FSASDSAEALNYMALAGWDSKQMMEGLSGVMDLAAASGEELGAVSDIVTDGLTAFGLK
                     AKDSGHLADVLAQTSSKANTDVRGLGEAFKYVAPVAGALGYTIEDTSIAIGLMSNAGI
                     KGEKAGTALRTMFTNLSSPTRAMGNEMERLGISITDSNGKMIPMRKLLDQLREKFKHL
                     SKDQQASSAATIFGKEAMSGALAIINASDEDYQKLTKSIDSSTGASKRMADTMESGLG
                     GKLRTLRSQLEELALTIYDRIEPALKIIVSAFSKVVTWVTKLPTSIQLAVVGFGLFVA
                     VLGPLVFMFGLFISVMGNAMTVLGPLLINVNKASGLFAFLRTKIASLVKLFPILGVSI
                     SSLTLPITLIVGALVGIGIAFYQAYKRSETFRNIVNQAISGVANAFKAAKLALQGFFD
                     LFKGDSKGAVTLEKIFPPETVAGIQNVVNTIRTTFFKVVDAIVGFAKEIGAQLVSFWK
                     ENGSEITQALQNIAGFIKATFEFIFNFIIKPIMFAIWQVMQFIWPAVKALIVSTWENI
                     KGVIQGAINIILGIIKVFSSLFTGNWRGVWDGIVMILKGTVQLIWNLIQLWFVGKILG
                     VVRYFGGLLKGLISGIWGVIKGIFTKSLSAIWNATKSIFGFLYNSVKSIFTNMKNWLS
                     STWNNIKSNTVGKAHSLFTGVRSKFTSLWNATKDIFTKLRNWMSNIWNSIKDNTVGIA
                     GRLWDKVRNIFGNMRDGLKSIIGKIKDHIGGMVDAIKKGLNKLIEGLNWVGGKLGMDE
                     IPRLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGRGNGPNGFRNEMIEFPNGKRVIT
                     PNTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFHFGTTMWKDIKSSASSAFNWTKDQIG
                     KGTKWLGDKVGDVMDFIDNPGKLLNYVLQAFGVDFSSLTKGMGIAGDITKAAWSKIKK
                     SAIKWLEDAFAESGDGGVLDMSKLRYLYGHTAAYTRETGRPFHEGLDFDYIYEPVPST
                     INGRAQVMPFHNGGYGKWVKIVKGALEVIYAHLSKYKVKTGQQVRVGQTVGISGNTGF
                     STGPHLHYEMRWNGRHRDPLPWLRKNNGGGKSTPGGNGAANARRAIKAAQNILGGRYK
                     ASWITNEMMRVASRESNYTANAVNNWDSNARAGIPSRGMFQMIDPSFRAYAKSGYNNP
                     LNPTHQAISAMRYIVGKWVPRTGSWRAAFKRAGDYAYATGGKVYNGLYHLGEEGYPEW
                     IIPTDPSRANEAHKLLALAANDIDNRSKNKRPNNLPNPSISNSDTNYIHTLENKLDAV
                     INCLVSLVESNQVIADKDYEPVINKYVFEDEVNNSIDKRERHESTRVRFRRGGTII"
     gene            25503..>25927
                     /locus_tag="RPH49_001708"
     CDS             25503..>25927
                     /locus_tag="RPH49_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HDY5124850.1"
                     /translation="MQDTIQIDNKTIGWLVVQRGFEIPSFNFVTEKENVKGRAGSIVK
                     NRYLNDIEFDLPLIIRNEKLSPGGEKTHDDILEALVKFFNIKDLTPKKLKFKSQNWYW
                     FAYFDGPLKLPKNPRGSVKFTIKVVLTDPYKYSVTGNKNT"
BASE COUNT         9921 a         3682 c         5206 g         7118 t
ORIGIN      
        1 agtaaaacct tgtattgccg gccgtcctag aacaaagggt aaagttgaat cgataatgaa
       61 aatattagat gaaattcatg catatcaagg cgaattatat ttggaagaga ttcctaagtt
      121 tatttctaat cttaatgagc gactgaacta ctcagttcat acgagtacag gtaaaatacc
      181 tattattgct ttagaaaaag aaaaaagttt cttacaacca ctaccgaatg tgaatgtaag
      241 aaactcatat aaagtgaaac ataaatattt gaaagtcaac cgctctaata tgattacata
      301 taagtccaat caatattcag taccagctga atattgtggg aaaatagttg aagttcaagt
      361 ttatgatcaa aaactacacg tttattataa cactaaatcg atttgtgaac atctcatcac
      421 acaacgtaaa ttaaattatc aaaaagaaca ttatttagaa acactgtcat cttcttttgg
      481 aaatagagaa atggatgata ttaatcagat tgcgatagat aatttgaatg cgattggaga
      541 gttgtatgat gaataattcg acgaattata agcgcttaaa agcgaattta gaatatttga
      601 aaatgaatca aatgattaat catcttgatg atgttatcga ttttagtatt aaaaataacc
      661 tgtcatttat agatacacta attaaattaa gtgactacga aatcgaaatt aaagagaaaa
      721 atttgattga atcgatggta aaggtggcgg catttccgtt taaaaaagaa atatcagact
      781 ttgactttaa ttttcaaccg agcatcaatc aacaagaaat ttgggatttt acagatttgc
      841 gttttataga aaaatatcaa aacattgtct ttttaggctc aagtggcgtt ggcaaaacac
      901 atttagctac aggcattggt atggctgcag ctaaaaatag agtgagtact tactttatta
      961 aatgtcatca tttgatagag aatttaagaa aagcaaaact tgagaacaga ttagaaaata
     1021 gattgaagca ctatagcaag tataagttat taatcataga tgagattggg tacttaccta
     1081 ttggaagtga agatgccaaa ctattctttc aattaataga tttaagatat gagaagaaaa
     1141 gtacaatatt taccacaaat atcaatttca acttatggaa tgaaatattt gatgatccaa
     1201 aaatcgcaaa tgcgattttg gataggatat tgcatcattc aagtgtagtt aaaatcaaag
     1261 gcaaatcgta tagattaaaa gatcattcac ctaagaagga aattacttag caaacaattt
     1321 tgtacattct tatacaatca tttatgtaca tttttatatt gacatttaca gtattgcaac
     1381 tttcatattc tataaagaat acttttatga agaataaaaa actgctactt gcgccaacaa
     1441 gtaacagtaa gtgttcatca aaatatacaa cttaattaaa tcaaaatata cggaggtagt
     1501 caactatggc tgaaaatatt aaaacagaac aacattatta cactaaagat ttctcaggat
     1561 acagaaatga agaagataat tttgtagcaa atcaagaatt gacagtaaca atcacattga
     1621 acgagtacag aaaacttatt gaaataaagg ctgttaaaga taaagaagaa gatacttaca
     1681 gaggtaagta ttttgcggaa gaaagaaaaa acgaaaaatt ggaaaaagaa aatataaaac
     1741 tgaaaaacaa aatttatgaa ttacaaaacg aagaagataa cgaggagtgc gaagaggagt
     1801 acgaagaata caaggaggac taaaagaatg tattacaaag cgggtgagat aaaaaataaa
     1861 attataaact ttaacgggtt cgaatttaaa gtgtctgcga tgaagagaca tgacggtatc
     1921 agtatacaag ttaaggatat gaataatgtt ccacttaaat catttcatgt cgtagattta
     1981 agcgaactat atattgcaat ggatgcaatg cacgacgtta taaacgaatg gattgaagag
     2041 aacacagatg aacaggacag actaattaac ttagtcatga aatggtagga ggtcgctatg
     2101 aagcagactg taacttatat cattcgtcat agggatatgc caatttatat aactaacaaa
     2161 ccaactgata acaattcaga tattagttac tccacaaata gaaatagagc tagggagttt
     2221 aacggtatgg aagaagcgag tatcaatatg gattatcaca aagcaatcaa gaaaacagtg
     2281 acagaaacta ttgagtacga ggaggtagaa catgactgaa caaactaatc aagatgtcga
     2341 tattttaacg caactaggtg taaaagacat cagcaaacaa aatgcaaaca agttttataa
     2401 atttgcgata tacggcaagt tcggtactgg taaaactacg tttttaacaa aagataacaa
     2461 tgccttagta ctagatataa atgaggacgg aacaacggta acagaagatg gggcagttgt
     2521 gcagattaag aattataagc attttagtgc agtgattaaa atgctgccta aaattattga
     2581 acaactaaga gaaaacggaa aacaaattga tgttgtagtg attgaaacaa tccaaaagtt
     2641 aagtgatatc actatggacg acatcatgga cggtaaatca aagaaaccga catttaatga
     2701 ttggggcgag tgtgctacac gcattgtaag tatttatcgt tatatttcta aattacaaga
     2761 acattatcaa tttcatcttg ctataagcgg gcacgagggc attaacaaag acaaagatga
     2821 tgagggaagt actatcaatc caacaatcac gatagaggca caagaccaaa taaaaaaagc
     2881 ggtcatcagt caatctgacg tgttagcaag aatgacaata gaagaacatg agcaagacgg
     2941 cgaaaaaact tatcaatatg tacttaacgc tgaaccatca aatttattcg agacaaagat
     3001 aagacactca agcaacatca aaattaacaa caaacgtttc attaatccaa gtattaacga
     3061 tgttgtacaa gcaattagaa atggtaatta aaaattaatt aaaaggacgg tataaaaatt
     3121 atgaaaatca ctggtagaac acaatacatt caagaaacta atcaagaggc attcatgaaa
     3181 ggtggggact ttttaggagc tggagaattt acagtaaaag ttgcaaatgt cgagtttaac
     3241 gacagagaaa acagatactt cacgattgtt tttgaaaaca acgaaggtaa acaatacaaa
     3301 cacaaccaat tcgtcccacc attccaacaa gattatcaag aaaaacaata tatcgagtta
     3361 cttagtagat taggaattaa attgaactta ccagatttaa cttttgacac agatcaatta
     3421 attaacaaaa tcggaactat tgtacttaaa aataaattta acgaggaaca aggcaagtat
     3481 tttgtaagac tctcatatgt aaaagtttgg aataaagacg atgaagtagt taataaacca
     3541 gaacctaaaa ctgatgagat gaaacaaaaa gaacagcaag caaatgggaa acagacgcca
     3601 atgagtcaac aatcaaaccc attcgctaat gctaatggtc caatagaaat caatgatgat
     3661 gatttaccgt tctaggacgt ggtttaaatg caatacatta caagatacca gaaagacaat
     3721 gacggtactt attccgtcgt tgctactggt gttgaacttg aacaaagtca cattgactta
     3781 ctagaaaacg gatatccact aaaagcagaa gtagaggttc cggacaataa aaaactatct
     3841 atagaacaac gcaaaaaaat attcgcaatg tgtagagata tagaacttca ctggggcgaa
     3901 ccagtagaat caactagaaa attattacaa acagaattgg aaattatgaa aggttatgaa
     3961 gaaatcagtc tgcgcgactg ttctatgaaa gttgcaaggg agttaataga actgattata
     4021 gcgtttatgt ttcatcatca aatacctatg agtgtagaaa cgagtaagtt gttaagcgaa
     4081 gataaagcgt tattatattg ggctacaatc aaccgcaact gtgtaatatg cggaaagcct
     4141 cacgcagacc tggcacatta tgaagcagtc ggcagaggca tgaacagaaa caaaatgaac
     4201 cactatgaca aacatgtatt agcgttatgt cgcgaacatc acaacgagca acatgcgatt
     4261 ggcgttaagt cgtttgatga taaataccac ttgcatgact cgtggataaa agttgatgag
     4321 aggctcaata aaatgctgaa aggagagaaa aaggaatgaa tagactaaga ataataaaaa
     4381 tagcactcct aatcgtcatc ttggcggaag agattagaag cgctaaaaaa attaaaaaat
     4441 ttacccctga ggattctaaa ggttttcctg atataacaaa agattcaata aaagaaccta
     4501 aataaaaata ttatggttga taaaatccca ttgttctttt gttaaccacc cttgtttgtt
     4561 attgactatt tctgtaacaa acagcttatc tccagaatcg agataaggtt tcaacttttc
     4621 tatcatttct gaagttgata aagaagaacg gaataaaaat gaagatttcc aataattgca
     4681 atgaccatta gaaatttcct tttttataac atttctcaat tcctcatatt tttgtccggg
     4741 tgagtttaaa tcatatgtta acatataagg tttttccata ttttattcac ccccaatcta
     4801 acgcagtagc gataacaaaa ttataccaga aaggagaatc aatatgactg atcaaccaag
     4861 ttactactca ataattacgg aaaatgttag agaggaagag tgtcaatgag caagccgaaa
     4921 tggaacagtg ctaaaaaaag aaaaatcaaa aacgaattaa cgcaaggaat ttataagtgt
     4981 gttatgtgtt cgaatatttt cgatagtgta gattgtttgc aaatagagca taaaatacca
     5041 atttcaaaag gtggtacaaa tgaaatgtca aatttaactg tactttgcca aaagtgtaat
     5101 tgtagcagaa agaatagagt tggaaatgaa catttaaaaa atattcttaa aaacatcgaa
     5161 aaagagatgg ataaaataaa cattgattta ctcgcttacg aaaaagaaat tggaactctc
     5221 gataatagag atatttcaga aataattaat gaactagaaa gtatatatac agatttccat
     5281 aatacgttgg ttggagaagt tttaaatgtc taaagataaa atcaaaaatt ccattactgg
     5341 ttacggtctt gtttttaagc gagtgatgaa agacacaacg ataagtattg aagcaaaggc
     5401 gttgtacagt tacttatctt catatgctgg tgtagatgaa acagcttttc caagtgtaga
     5461 tctaataaag catgaattag ccataggtaa gcaacggtat caaagagcaa gaaaagagtt
     5521 agaaacagca gggtatttac aagttgacag aaaacaaaac ggtaatatct atggaagtaa
     5581 tttatacaca atttaccaca gtcctcgatg ggttgattct cgaccggtcg aaattcaatc
     5641 ggttgaaatt caatcgctcg acaaccagcc cactacaatt aacagtatta caaataacaa
     5701 ttatacaaat aacaataaga caattaataa tagcgcaact gacgttacgc atgagcaatt
     5761 tgaggaatgg tggaaacttt acgacaagaa gaaagataag aaaatatctt ttactaaatt
     5821 caaatcatgc ttaaagaaac attcttttga acaaatcatg caaggtactc gtgagtattt
     5881 aaaaactatt acagacaaac aatatcaaaa gtaccctaaa acgttcttaa ctaacgaaag
     5941 ctatatgaat gattatagcg aagagattaa agaaactggc atagatcaat tggaacgcat
     6001 gaagtacgac gaaagttatt gggactagga ggatgttatg aaaccgttat tcaacgaaaa
     6061 aataaacgaa agtttaaaaa agtatcaacc aatcgaagta atactaagac agaattgcga
     6121 taaatgtggg cgtcaatatg acttatataa gtttgaaaat ggatatgaat acaaagacgg
     6181 ttgcgaatgt gaaattcaaa gattggctta tgaagaatac aaaaggaata aacaaaagaa
     6241 acttgattat attttcaatc aatcaaatgt taatccgtct ttaagagatg caacagttaa
     6301 caactataag ccacaaaatg aaaaacaagt acaagctaaa caaacagcaa tagagtatgt
     6361 acaaggcttc tctacaaaag aaccgaaatc attaatattg caaggttcat acggaactgg
     6421 taaaagccac ctagcatacg ctatcgcaaa agcagttaaa gctaaaggac atacggttgc
     6481 ttttatgcat ataccaatgt taatggatcg tatcaaagca acatacaaca aaaatgcagt
     6541 tgagactaca gatgagttag tcagattgtt aagcgatatt gatttacttg tactagatga
     6601 tatgggtgta gagaacacag aacacacttt aaacaaactt ttcagcattg ttgataacag
     6661 agtaggtaaa aacaacatct ttacaactaa ctttagtgat aaagaactaa atcaaaatat
     6721 gaactggcaa cgtataaatt cgagaatgaa aaaaagagca agaaaagtaa gagtaatcgg
     6781 agacgatttc agggagcgag atgcgtggta atcacaaaac aaaatataaa agaaatatta
     6841 cattgtagag atgtatatgc tcaaaagatg attgattttg caaacggaga ccaagagaaa
     6901 cttaaaaaac ttattgatga taagttgaaa gaaaaagaag aaagacccgc aatcgtcgaa
     6961 tattaaggag tgttaaaaat gccgaaagaa aaatattact tataccgaga agatggcacg
     7021 gaagatatta aggtcatcaa acatgaagat aacgagaatg aagtttattc gctcacagga
     7081 gcccatttca gcgacgaaaa gaaaattatg actgatagtg acctaaaacg atttaaaggc
     7141 gctcacggac ttctatatga gcaagagcta ggtttacaag caacgatatt tgatatttag
     7201 aggtggcgca atgagtaaat acaatgctaa gaaagttgag tacaaaggaa ttgtatttga
     7261 tagcaaagta gagtgtgaat attaccaata tttagaaagt aatatgaatg gcactaatta
     7321 tgatcatatc gaaatacaac cgaaattcga attattacca aaactagata aacaacgaaa
     7381 gattgaatat attgcagact tcgcgttata tctcgatgac aaactgattg aagttatcga
     7441 cattaaaggt atgccaaccg aagtagcaaa acttaaagct aagattttca gacataaata
     7501 cagaaacata aaactcaatt ggatatgtaa agcacctaag tacacaggca aaacatggat
     7561 tacttacgag gaattaatta aagcaagacg agaacgcaaa agagaaatga agtgatctaa
     7621 tgcaacaaca agcatatata aacgcaacga ttgatataag aatacctaca gaagttgaat
     7681 ataagcattt tggtgatgtg gataaagaaa aagaaacgct ggcagattac ttatataaca
     7741 atcctaacga aatactagag tatgacaatt taaaaattag aaatgtaaat gtagaggtgg
     7801 aataaatggc gaaaacagca agaattgtaa ggatacacga taaaccttat aggttcagta
     7861 aatttgaaat ggaattaatt gaaagtcacg gtataacacc cggaatggtt tctaaaagag
     7921 taaaggacgg ttgggaacta catgaagcaa tggacgcacc agaaggcatg cgtttaagcg
     7981 agtacagaga aaaggaaaca atagaaagac tggaacaagc tagactcgaa cgtaaattgg
     8041 aaagacagcg aaagaaagag gcagagctaa gaagaaagaa gccacattta tttaatgtgc
     8101 ctcaaaaaca ttcacgtgat ccgtactggt ttgatactac ttataaccaa atgtttaaga
     8161 aatggcagga agtataaatg cctaaaaccg atagcgcacg caaagaatac ttaaaccaat
     8221 ttttcggatc taagagatat ctgtatcagg ataacgaacg agtggcacat atccatgtag
     8281 caaatggcac ttattacttt catgggcata tcgtaccagg ttggcaaggc gtgaaaaaga
     8341 catttgatac agctgaagag cttgaaacat atataaagca acaggatttg gaatatgagg
     8401 aacagaagca actaacttta ttttagagga ggttatgaaa gtgaactatg aaacaggatt
     8461 ccaaataggc gtaatggaag ctaggttgaa gaagatgaga aaacaacgtg atgagtacaa
     8521 gaagcaacgt gacgagctta ttggggatat agctaagtta agagagcgta acgaagagct
     8581 ggagaacatg tggcgcacag tcaaaaatga attgcttgga agatacgaac attactgttt
     8641 taaatttaga gaactacacc ctgagagcaa agcgaacagg ataggagctc tctatatagg
     8701 aggtaaaagc actgcagata ttataatgtc gcgaatggaa gaactagacg gaacaaatga
     8761 gttctacgaa tttttagggc aaatggagga agacacaaat gaataaccgt gaacaaatag
     8821 aacaatccgt tataagtgct agtgcgtata acggcaatga cacagaggga ttactaaaag
     8881 agattgagga cgtgtataag aaagcacaag cgtttgatga aatacttgag ggtttaccta
     8941 atgctatgca agatgcactc aaagaagata ttggtcttga tgaagcagta gggattatga
     9001 cggggcaagt ggtctataaa tatgaggagg agcaggaaaa tgactaacac attacaagta
     9061 aaactattat cagaaaatgc tagaatgccc gaacgaaatc ataagacgga tgcaggttat
     9121 gacatattct cagctgaaac tgtcgtactt gagccacaag aaaaggcagt gatcaaaaca
     9181 gatgtagctg taagcatacc agagggctat gtcggactat taactagccg tagtggtgta
     9241 agtagtaaaa cgcatttagt gattgaaaca ggcaagatag acgcgggata tcatggtaat
     9301 ttggggatta atatcaagaa tgatgcacaa gtatatttaa caactaacga acagtgtttt
     9361 gatatacaag gagaaatgga aaattctttt gtaaataatg ctaagaaaaa accttttact
     9421 ataaatgatt attacgaaat atataaaggc gacaaactag ctcaattggt tatcgtgcct
     9481 atatggacac ctgaactaaa gcaagtggag gaattcgaga gtgtttcaga acgtggagca
     9541 aaaggcttcg gaagtagcgg agtgtaaaga catcttagat cgagtcaagg aggttttggg
     9601 gaagtgacgc aatacttagt cacaacattc aaagattcaa caggacgcaa gcatacacac
     9661 ataactcgag ctaaaagcaa tcaaaggttt acagttgttg aggcagagag taaagaagaa
     9721 gcgaaagaga aatatgagtc acaaaataca cctattgttt actacactaa taattctaaa
     9781 gtgaccttat tcgaaagacc tagtgaagaa gtattaggtt ctttgttcga aaagaaataa
     9841 aatcattaaa gaggggagat aataatgttt aatacaccta aaatgaaatt accagaaaag
     9901 cacaccgagg tatttaagac gtataaaaat ggaacgccag aagaaaaagc tgagattgaa
     9961 ggctgtttta ttaaaactgt taaagatgaa gatagtgaat tttacagccc tatgttagcc
    10021 agtctaaatg aacaacagtt aaagagtatg ttgagacagg tacttttttt gattgataca
    10081 ggagatgaca atgatgatta aacaaatatt aagactaata ttcttactag caatgtatga
    10141 gctaggtaag tatgtaacgg agcaagtata tattatgatg acggctaatg atgatgtaga
    10201 ggtgccgagt gattacgtct ttcgagcgga ggtaagtgag tgatgtggat tactatgact
    10261 attgtatttg ctatattgct attagtttgt atcagtatta atagtgatcg tgcaagagag
    10321 atacaagcac tcagatatat gaatgattat ctacttgatg aagtagttaa aactaaagga
    10381 tacaacgggt tagaagaata caggattgaa ttgaagcgaa taaataacga tattaaaaag
    10441 taatttatat tatcggaggt attgcatgta taacaggaaa gaaatacgtg aaatgataga
    10501 taactacaag tggatgaaga acataataga cagtaaagtc tacgataacg aaagtacatc
    10561 aattgcacaa tatggttatc aatctgcgat gccaaaagct aaaggcacga ctagcaataa
    10621 agtgttagtg aaagttataa acaaaaacaa agcgcttaga aagtacgatt acttgattaa
    10681 gaagatagcg ttcattgatg aatatgaaga atacatcacg aatgaaaaag attatcatat
    10741 tttacaaatg ttaaaacaac gagaaagcca taataggatc atgagcattc ttgatatagg
    10801 cagagacaat ttttattcta gagtaaaaga tatagtaaat atactttata acttgcaaca
    10861 agaaaccgac agttcggaca catcgtacag ttcggacaca tcgtacagtt cggacacatc
    10921 gtacagttcg gactaatttt gatgctacat attgtttttt attataattg ctgtgtagca
    10981 aaacatttat atttcttttg aactctcaca ttaagtgagg gtttttattt ttataaacaa
    11041 gaggtggaga atggagatat caaagtacca agagatagct acacgtacac acaatgatga
    11101 attgaattta aatgaatcta ttacttgtta cggcttaggt ttaactcaat ctacaggcaa
    11161 tgttacagat ctaattaaac agcatatgtt ttgtaatgta ccgatagata aaggaattat
    11221 gataaatgaa cttagcgaag cattgtggaa tatagctaat cttactaacg tgttaggtat
    11281 taacttggat gagatagctg gtcatagtgt taacactatc ttgatgaata aacctaatca
    11341 gactatcaat ttagacaatg gtataaaaca aggagacaaa gtattgtttc aaggtagtaa
    11401 gtatcttgtt gatggatcga taggaaactt attgttaatt agcaatgata aagatgatag
    11461 acaagtaact gtgcaagatg ttaagaaagt cgacaaggag tgatggcatt gtctattatg
    11521 aagcgatgtg gtcatccaac attaatgtat tgattaatca taatgaaagt tattgtgata
    11581 aacacaagca atatgcaaat gaaaattaca atgatttgag acgtcgaaac gatccagagt
    11641 atttaagatt ttataaatcg aaaacgtggc aaaacatgcg tcgaattgta ttgttagaac
    11701 atgattttat ttgtgtttct tgtggcaatc aagcgactat ggttgaccat attgtaccaa
    11761 caaaaattga ttgggcaaga agattagaca aaagtaattt acagcctttg tgtgatgctt
    11821 gccataacca aaagacaaaa gaagatttga agaaatatta aaaaagataa aaataggaag
    11881 tccccccaaa gatgaaacgg gcgtcaatga aaggttctgg agaacggagc agagttttct
    11941 tctcaaaaaa ttccctttat ttaagttttt ttagtaggag gtgctaattt atggcgggta
    12001 gacctaagaa gcttttgtca aattcgaaca agaattatac aaaagaagaa attattgaaa
    12061 aagagcgtca agaagctcaa ttaaataaat tttctaaaat cgatactgaa ccaccgcact
    12121 ttttagatga aatagcgaaa caagaatact taagaatatt accgcacatg caagaattgc
    12181 caatttccaa cttagataaa gcacaattag cacaatattg tagtttttat agtgactttg
    12241 ttaaagcaag tttgatttta gagcgcgaag acttgatttt agaagacgac aaaggaaatc
    12301 aaaaggttaa tccggcgttc aacataaagg aaaaagcggg tattcgattg caacaaacag
    12361 ctaatacttt aggattaact attgatagcc gattgcgtat tatggttcct gatgaaaaag
    12421 aagatgatga tccatatatg gaatttgtga gtgattagta atgactgatt atgttactaa
    12481 atacgcaaaa aaggtagttt caggagaaat tttggcaagt ttgaagaata ttcaagtatg
    12541 taaacgtcac ctatctttta tggagaaccc gccgaatggt tgccattggg ataatcattt
    12601 gtctaacaaa gcaattaaat ttgtggaaat gcttccagac cctaaaacaa accagcccat
    12661 gcctcttatg gagtttcaga aattcattgt tgggagctta tacggctggc gtagaggtca
    12721 atacagaatg tttactaaag cttatataag tatggctaga aaacaaggta agtctctaat
    12781 cgtatccgga atgtccgtta acgaactgtt gtttggacaa taccctaaat ttaatagaca
    12841 aatttatgta gcttcatcta cttataagca agcgcaaaca atattcaaga tggcaagcca
    12901 acaagtaaac ctaatgcgaa gtaaaagcaa gtttatccgt gaaaaaacag acgtaagaaa
    12961 gacagacatt gaagatgtat taagtagttc agtgtttgca cctctttcca ataacccaga
    13021 tgcggttgat ggtaaagatc ctacagttgc tattttggac gaattggcaa gtatgcctga
    13081 tgatgagatg tactcaaggt ttaaaacagg tatgacatta caaaaaaatc ctttaaccct
    13141 acttgtttca acggccggag acaatttaaa tagtcaaatg taccaagagt ataagtatat
    13201 taaacgtatt ttaaatgaag aagtaagagc tgataattac tttgtatatt gtgctgaaat
    13261 ggattcacaa gaagaagttc aagatgaaac aaagtggatt aaagcaatgc cgcttttaga
    13321 atcaaaagaa catagaaaaa ctatacttca aaatgtaaaa gctgatatac aagacgaatt
    13381 agaaaaaggg acatcgtatc ataagatttt gattaaaaac ttcaatttat ggcaagcgca
    13441 aagagaagat agcttgctag atatttcaga ttgggaacaa gtaataacgc ctatgcctaa
    13501 tatcaatggt aaagatgtgt atataggtgt cgacttatcg agattggatg acttaacatc
    13561 tgtagggttt attttcccta acgacgataa aaaagtgttt ttacatagtc attctttcat
    13621 tggattaaga acaaacttag aacaaaaatc taagagagac aaaataaatt atgaattagc
    13681 gattgaacgt ggagaagctg agactacaca atcagatagc ggcatgattg attataaaca
    13741 agttatcgat tttatagtga aatttataac gacgcatgac ctgaatgtac aggctgtttg
    13801 ctatgaccct tggaatgcgc aaagttttat aacaacaatc gaatcaatgg ctttagattg
    13861 gccactcatt gaagtgggac aaagttttaa ggcgttatca caatctatta aagaatttag
    13921 aatgtgggtt gcagatgaaa gaatacagca taacgataat atgttactta caacatcagt
    13981 taataatgcc gttttgattc gtgacggaga agacaatgtg aaaataaata aaaaaatgaa
    14041 tcgtcaaaaa atagatccga ttatttcgat tatcacagct ttcactgaag ctagaatgca
    14101 cgaattccaa gaaaattgga cggagaaata tgaaagcgaa gaattcggat tttaaaggtg
    14161 gtgacaaaat ggacttgaat aaaataaatg tcttttttaa tttcttggtt gctaatttgg
    14221 ttagcatcct ttttttatta ggtttgtttg tggttaatgt ttctgtgtat aaagcattcg
    14281 gtcaaaatat aggacttcta tgcattggta taacactgat tgttatttcg ttgattttaa
    14341 atcacgaaag caatcaagaa aggagttagt agttgtgggg attttttata aaaattaaaa
    14401 acgagacttg caatacaacg aagatgattt gcaaatgatg gttcaaactt tgccaggttt
    14461 tcaaggaaca aaattacgac aatataaaga tatagaagca attaggcata gcgacatctt
    14521 tactgcagtt atgatgattg cttctgattt ggcgcgcatg ccaattaggg tgacagtgaa
    14581 cggccaaatt aattatagtg acaggattgt taatttgtta aatacacgtc ctaacccaat
    14641 gtataacggc tatatattca aattagtagt gtttgttagt gccttactaa catcgcacgg
    14701 ctatattgaa attacacgtg ataaaacagg agaacctatg aatttaacgt tcagaaagac
    14761 atccgaaata gaattgaaat cagacgcaag aggtcgactg tattattttc atcaaaggat
    14821 agacagtaac ggaaataata tagaacgtaa tgttaagttt gaggatatgc tagacatcaa
    14881 attttattcg ttggatggta taaatggttt gtcactgtta gacacattaa gtcgcacgat
    14941 agaatcagat aacaatggaa aagatttcct taataatttc ttgcgaaatg gcacacatgc
    15001 tggtggtatt ttgaaaatga aaggtgtatt agataataaa aaagcaagag accgtgccag
    15061 agaagaattt cacaaaagtt ttagtggaac taaacaagct gggaaagttg tcgtactcga
    15121 tgaatcaatg acgtttgatc aattagaagt tgatacagaa gttttaaagc ttatcagaga
    15181 aaacaaatca tcaacaagag aaatagcagg tgtatttggt attccattgc ataagttcgg
    15241 catagaaaca gcgaacatga gtatcacgga tgctaattta gattacttat caactttaaa
    15301 accttatatt acatgcgttt gtgcagaatt gaattttaag tttaatgatg aatatgtgaa
    15361 tcgtgaattt aaatttgata ccactgaaat acgagttgtt gatgaaaaaa cacaagctga
    15421 aattgacaaa attaacattg attctggaaa gatgaatatc gatgaaatta gacaacgtga
    15481 tggattagcg ccaataccag gcggtaatgg tagcattcac agagtcgatt taaaccatgt
    15541 aaatattgaa cttgtagatg agtatcagat gaataaatcg agagctactg ataaaaaatt
    15601 gaaaggtggt gaggaaaatg agtaaggaaa cgagagttgg caacattatt gaggtacgct
    15661 caaatgataa caacgaaatg gtcatagagg ggtatgcgtt aaagtttgac acttggtctg
    15721 aaaatcttgg tggattcaaa gaaacgattt cacgtcgcgc tttagaaaac actgatttat
    15781 ctgatgtgcg ttgtttagta gatcatatcc catcgcaaat aattggtagg acaaaatcgg
    15841 gtactttgga gctcgaaact gatgatgttg gacttaaata tcgttgtaag ttaccaaaca
    15901 caacatttgc acgtgattta tatgagaaca tgcgtgtagg caacatcaat caatgttcgt
    15961 ttggttttat gcttgacgat aaaggcgatg aagtgcgttt tgatgaacaa gaaaacattt
    16021 acaaacgtac tttaacagca attcgtgaac ttacagatgt ttctgtagtg acttatccgg
    16081 cttacaaaga cactgatgtt aaaccagcat tacgtagtat tgaaaccgtt aaaaaagaac
    16141 aacgtaaaaa agaattagaa ataagactaa agaaacactc tatattaaat aatatttggt
    16201 gaagttgaac accattatca aatacagcca ttggacatgc tgaatatagc gatgtctatt
    16261 tttttatgcc aattttagga ggaaattaaa tgaaaacaaa agaagagtta caatctgaga
    16321 tttcagacat taaaagacaa attgatttaa aggtgaagta tgcaacgaga gcacttaata
    16381 acgatgagtt agaaaaagca gaaaaattag aacaagaaat tactgattta cgttctcaaa
    16441 tccaagaaaa acaagaagaa ttagataagc taaaagaaaa agatggaact tcagaaaaca
    16501 atcaacaatc agtggaagta aacgaagcac gtacttatcg aaaccaagca aacattaatg
    16561 atttaggtat ttcgattcaa aacacaaagg taacatcaca agaagttaga gattttactg
    16621 aatatcttga aacacgcaat gatattcaag gtggttcgtt aaaaacagac tcaggatttg
    16681 tagttattcc agaggaaatt gttacagata ttttaaaatt aaaagaggtt gagtttaatc
    16741 ttgataagta tgtgacggtc aaacgtgtta caaatggttc tggtaaatat ccggtagtac
    16801 gacaatcaga agttgcagcc cttgaaaaag ttgaagaatt agaagaaaac cctgaattag
    16861 cagttaaacc attcttccaa ttagcatatg atattaatac acaccgtggt tacttccgaa
    16921 tttcacgtga agcaatcgaa gatgcaaaag tgaatgtttt gcaagaattg aaactatgga
    16981 tggcgcgaac tattgcagca acacgaaaca aagcaattat tgatgttatc actaaaggat
    17041 caacgggttc tacaagttca ggttttgaaa aagaaggcaa gaaattagaa gttaaaaaag
    17101 caaaatcttt agatgatatt aaagatgcta ttaacctgaa tgttaagcca aattacgaac
    17161 ataatgttgc gattgtttcg caaactatgt ttgcaaaatt agacaaaatg aaagataagc
    17221 taggaaacta tttaatccag ccagatgtta aagaaaaaac gcaacagcgt ttattaggag
    17281 ctaaaatcga aattttacct gatgaagtac tagggcaaaa aggtaataac actttgatta
    17341 tcggtaactt aaaagatgcg attgttttat ttgaccgctc tcaataccaa gcatcatgga
    17401 ctgactacat gcatttcgga gaatgtttaa tgattgctgt acgtcaagac tgtagaattc
    17461 tagattataa atcagcaatt gtgattgaat atgatgatag tgaacgcggt gaaggcgatc
    17521 ttggcttaga agcataataa gcgctcgata ctttataaag aggtgataaa ctatggcaat
    17581 gtatgaagtg aagaaatctt atactgactt ggaaaaaggc cagtatttaa agtcaggtaa
    17641 acgtgttgaa atgacagtaa aacgtgctga atatgttaac aaaaagctga aagagcatgg
    17701 agtaatactt gaaagagtaa aagaagaata ggtgattgaa tgcaattaac agctgaggaa
    17761 cttaagttat taaaaaagca ttgcaaaata gatcacaatt cagaggacga cttattagaa
    17821 atatattact cttgggcatt ccatgaaata gctagcgctg ttacggatga accaagtaaa
    17881 tatattgatt ggtttaaaag tcatcctcta tttgctcgtg ctatataccc tttagcaagt
    17941 tactattttg aaaaccgtat tgcttatttg gatagggatt tatcgcttgc gccacatatg
    18001 gttttaagta cggtgcataa attgagaggt tcatttgagc gatttttgga gagtgaaaat
    18061 gatgaaattt aattccaata aattaaatga acgtatagat ttttgtgaag atgtaagcga
    18121 gagagtgaac ggaaatccga tgaaaccgaa gacgaaaata ttatactctt gtttcgcttg
    18181 cattcaagaa tctaaagaat ccgacactca aacgaatctc aatacaggta gcaaattcat
    18241 taaaactatt attatcagag atacacgagg tgattataaa ccaacaaata agcattacgt
    18301 cttgcatgaa gggcaaagat ttaacatcaa atatgtaaag ccagattatc aagataaatc
    18361 ttatttgcgt atctatggcg aggtggtcat ttaatggggg caagaattga aagtaataac
    18421 atcgaacaag gtttgaaaaa tgcagtttta aaaatgaatt taaatagtaa tgtaattgtc
    18481 aaagctgggg ctatgtcatt agtcccgctt ttaaaaagta atacaccttt tgcgaatact
    18541 aaaaagcatg ctcgcgatca catagctgtt tctaatgtga aaacagacag acacacaagt
    18601 gagaaaattg ttacaattgg ttacgctaaa ggcgtctcac atcgtattca tgcaacagaa
    18661 tttggaacaa tgtaccaaaa accacaattg tttataacaa aaacagaaaa gcaagggaaa
    18721 aacaaagttt taaaaacaat gcttgatact gctaagaggt tgcaaaaatg attaatgtta
    18781 ccgaattaat tagaaacgct attattgcaa ataacattac agatgaagtg aatgtgttta
    18841 actacactat agatgaccat tttcacgaaa aaactgacaa gcctattatt cgtatatatc
    18901 ccttaccgtt caatcctgac acatacgctg atgataacga gatttcaaga gaataccatt
    18961 accaaattga tgtttggtgg tctcaagatg aaccgaacga gcaagcagaa aaaattgttg
    19021 agttactcaa agtgataaat tttcaatgtt attacagaga accgttatac gagagtgacg
    19081 tcatgtcatt cagacatatt ataagagcaa aaggctcgat tttatcaatg aaattggagg
    19141 aaaattaaat gattgaaaaa ttgaaacaag caccaagatt tttaaaatta aacttacaac
    19201 attttgcaga tacaggagtt tcgggtatcg caattggggt atcaaacttt tattatgcac
    19261 ctattttaaa agatacagaa aatgaatggg aaactggagc tggcacacgt attcgtttct
    19321 taaaagaaat tgaagtagac cgtccacaag ataccgagga agattatggg gatgatatgg
    19381 tcgcagcaac tgctgtatct aatggtaaac taagtgttaa gacaacattt gttactgttc
    19441 ctgctgacga taaggcgttc ttgaatggcg ctaaaaaagg tgtaggtggt tataaatatg
    19501 gagctaagga tatcccgcca gatgtagcga ttgtatttga aagacgtaat catgatgagt
    19561 cttcagaatg ggttggcttg ttcaaaggta aattcactcg ttcaagcatc aaagggcaaa
    19621 caaaacaaga taaagttgaa ttccagaatg acgacgtaga aggcaatttt attgatcgtt
    19681 tgtttgatga gagctcgcat gttactgact atgataaaaa aggaagcact acagggcgcg
    19741 attatgtatt catggaaaca tttggtaaaa cttatgatga attcatgtct agtcgaggag
    19801 aacaaaatat ggaacctgta gaaaaagaaa tgaaaaaaac agaaaaagtt gaagtcactt
    19861 ctgtaaacgt cactgatgaa caagttacag ttaaagttga tgctactaaa caactatcag
    19921 ccacaaccga accatctgga cagaaagtaa cttatgcagt gactgagggg caaacgtatg
    19981 ctagcgtaac atcaactggc ctcgttaaag gtttggcgga aggtaatgcg accgttacag
    20041 cgactgcagg aaagcaaact gatactgtgc aaattacagt acaatctaat ttagaaatgt
    20101 aagttttgag ggcttaatgc cctcttttta ttttggccaa attaaaaaga aagtaggaat
    20161 ttaataatgg aacgtacatc aattgaatta attacaggat ttacaaaaac aggaaagccg
    20221 caatatcaaa agtatttagc gaagccgatt attactttgt ttgaaacaat tcaaggttca
    20281 aaattaggtt tgaaacttaa caaagccttt aagggggctg attttaaaga tctaacagaa
    20341 gaagaattta ataacttaag tgtgacagaa caggaagaat acaaaaacaa gcaagaagaa
    20401 tacgaaaaca acatggctgt acaaatggaa gtattagaag aagttttgga tttcatcgtt
    20461 gaagcttttg ataatcaatt taccagtata gaacttcaaa aaggattacc aaatggtcaa
    20521 gaaggtattg aaaagattgg acagttaatt ggacgaatta caggtgggga acctagcgat
    20581 acaaaaaagt tcgtgacaga gaatcagaaa taagaaaaga agatttaaca cctgaagctg
    20641 tctacaacaa ttacaggaaa atagctaaag atttgataga aaagggcatg gatgcagaaa
    20701 aagtggctaa catgccgata cacttctttt tagacattgt cgaatcgaag attgaaacaa
    20761 agcgaactgc gaaaagtttt aaagatattt tttaatcagc ctttaaaggt tgatttttta
    20821 tttacatctt ggaagaaagg aggtttttaa atgcctaatc ctataggtaa tatggtcata
    20881 aaggttgatt tagatggttc tggattcaat agaggtgtga caggtttaaa taggcaaatg
    20941 aaaatggttt cgcgtgagct ttcggctaat ttatcacaat tttctagata tgataattca
    21001 ttagaaaagt cgaagataaa agtcgaaggt ttgagtaaaa aacaaaaagt tcaagcccag
    21061 attactaaag agctgaaaga tagttatgac aaacttagta aagaaactgg tgaaaacagt
    21121 gcaaagacac aagctgcggc tgctaaatac aatgaagctt acgctaaatt aaaccaatat
    21181 gagcgagagt taaaccaagc cacacaagaa ttaaaagaca tgcaaagaga gcagaaagca
    21241 ttaaatactg caatgggaaa acttggtacc aactttaata attttggtcc taaacttcaa
    21301 gaaattggta acagtatgaa aaatgtaggc cgtaacatga ctatgtatgt aactgcgccg
    21361 gtggttgctg ggtttgctgt agcagctaaa aaaggtattg aattcgatga cagtatgaga
    21421 aaagttaaag caacttcagg tgctactggg gaagagtttg aagctttgaa gaaaaaggct
    21481 cgcgaaatgg gtgcaacaac aaaatttagt gcatcagatt cggctgaagc attaaattac
    21541 atggcacttg ctggttggga ttctaagcaa atgatggaag gtttaagcgg agttatggat
    21601 ttagcggcag catctggcga agaactggga gcagtaagtg acattgttac agatggacta
    21661 acggcatttg gtttaaaagc aaaggatagt ggtcatttag cggacgtttt agcacaaact
    21721 agctcgaagg caaatacgga tgtcagagga ctcggagaag cttttaaata tgtcgctcct
    21781 gtagcaggtg cgttaggtta cacgattgaa gatacatcta ttgcgatagg tttaatgagt
    21841 aatgctggta tcaaaggtga aaaagcaggt acagcgttac gaacaatgtt caccaatctt
    21901 tcaagtccaa ctagagctat ggggaatgaa atggaacgct taggaatatc tattacagat
    21961 agtaatggga aaatgattcc tatgcgaaag cttttagacc aactgaggga aaaatttaaa
    22021 catctttcaa aagaccaaca agctagttct gcagctacaa tatttggtaa agaagcgatg
    22081 tcaggagcat tagcgattat aaatgcttct gatgaagact atcaaaagtt aaccaaatct
    22141 atagattcat ctaccggcgc atctaaaaga atggccgata caatggaatc tggtttaggt
    22201 gggaaattaa gaactttaag gtcgcaatta gaagaactag ccttaacgat ttatgacaga
    22261 atagaaccag cactaaagat tatagtaagt gcttttagca aagtagtgac atgggttact
    22321 aaattaccaa cgtcaattca attagcggtt gttgggtttg gattatttgt agcagtttta
    22381 ggtcctttag tttttatgtt cggtttattt atcagcgtga tggggaatgc aatgacagtt
    22441 ttaggaccct tgttaataaa cgttaataaa gctagtggtt tattcgcgtt tttaagaact
    22501 aaaatcgcat cacttgttaa actatttccg attttaggtg tgtcgatatc aagtttaacg
    22561 ttgcctataa cattaattgt aggtgcatta gttggtattg gcatagcttt ctatcaagct
    22621 tataaacgtt cagaaacttt tagaaatatt gtaaatcagg caatctctgg tgtagcaaac
    22681 gcatttaaag cagctaaact agcgttacaa ggtttctttg atttattcaa aggtgatagt
    22741 aaaggcgcgg ttaccctaga gaagatattt ccacccgaaa ctgtagcagg aatacaaaat
    22801 gtagttaata cgattagaac aactttcttt aaagtagttg atgcaatcgt tggtttcgcc
    22861 aaagagatag gcgctcaatt agtctctttc tggaaagaga acggctcaga aataacacaa
    22921 gctttgcaaa atatagctgg tttcattaaa gcaacctttg aatttatttt taactttatt
    22981 attaaaccaa tcatgtttgc gatttggcaa gtgatgcaat ttatttggcc ggcggttaaa
    23041 gctttgattg tcagcacttg ggaaaatatc aaaggtgtaa tacaaggggc tattaatatt
    23101 attttgggta ttatcaaagt gttctctagt cttttcacag gaaactggcg aggtgtttgg
    23161 gacggcattg taatgatact gaaaggtact gtgcagttaa tttggaattt aatacaactg
    23221 tggtttgtag gtaagattct aggtgttgtt agatactttg gtggattgct taaaggttta
    23281 atatccggta tctggggtgt tatcaaaggt attttcacaa aatcattatc tgcaatttgg
    23341 aatgcaacga aaagtatttt tggtttctta tacaatagtg ttaaatctat tttcactaat
    23401 atgaaaaact ggttatctag tacgtggaat aatatcaaaa gcaataccgt cggcaaggct
    23461 cattcgttat ttacgggtgt aaggtctaaa ttcacaagtt tatggaatgc gacgaaagat
    23521 atatttacta aattaagaaa ttggatgtca aacatctgga actctattaa agataacacg
    23581 gtaggtatag ctggtcgttt gtgggataaa gtacgtaata tcttcggaaa catgcgtgac
    23641 ggtttaaaat ctatcattgg taaaattaaa gatcatatcg gcggtatggt agatgctatt
    23701 aaaaaaggac ttaataaatt aattgaaggc ttaaactggg tcggtggtaa gttaggtatg
    23761 gatgaaatac ctaggttaca cactggtaca gagcacacac atactactac aagattagtt
    23821 aagaacggta agattgcacg tgatacattc gctacagttg gggataaagg acgtggaaat
    23881 ggtccaaatg gttttagaaa tgaaatgatt gaattcccta atggtaaacg tgtaatcaca
    23941 cctaatacag acactactgc ttatttacct aaaggctcaa aagtatacaa cggtgcacaa
    24001 acttattcaa tgttaaacgg aacgcttccg agatttcatt tcggtactac tatgtggaaa
    24061 gatattaaat ctagtgcatc atcggcattt aactggacaa aagatcaaat aggtaaaggt
    24121 acaaagtggc ttggcgataa agttggtgat gtcatggact ttatcgataa tccaggcaaa
    24181 cttttaaatt atgtacttca agcgtttgga gttgatttca gttctctaac taaaggtatg
    24241 ggtattgctg gcgatataac aaaagctgca tggtctaaga ttaagaaaag tgcaatcaag
    24301 tggcttgagg atgctttcgc agagtcgggt gatggcggtg tattagatat gagtaaatta
    24361 cgttacttat acggtcacac tgctgcttat acacgagaaa ccggacgccc attccatgaa
    24421 ggtctggatt ttgattacat ttacgaacct gttccatcaa ccattaatgg tagagcacaa
    24481 gttatgcctt ttcataatgg tggttatgga aaatgggtga aaattgtaaa gggcgcctta
    24541 gaagttattt atgcacattt atctaaatat aaagttaaaa ctggtcaaca agttagggtc
    24601 ggacagactg ttggtatatc ggggaatacg gggtttagta caggacctca cttacattat
    24661 gagatgcgtt ggaatggaag acatagagac ccgttaccgt ggttaagaaa gaataatggg
    24721 ggcggcaaaa gtacacccgg tggtaatggt gcagctaatg ctagacgagc tattaaggct
    24781 gctcaaaata ttttaggagg aaggtataag gcgagttgga ttactaacga gatgatgcgt
    24841 gttgcgagtc gtgaatccaa ttatacagct aatgcagtca ataattggga tagcaacgca
    24901 agagctggta taccttcaag aggtatgttc caaatgatag atccttcatt tagagcgtac
    24961 gcaaagtcgg gttacaataa tcctctcaac ccaactcatc aagctatatc ggctatgaga
    25021 tatattgtgg gtaaatgggt accaagaaca ggctcatgga gagctgcgtt caaacgcgct
    25081 ggtgattacg catatgctac tggtggcaaa gtctataacg gattgtatca cttaggggaa
    25141 gaaggatatc cagagtggat aatacctact gatccaagta gagcgaacga agcacacaaa
    25201 ttattagctt tagctgctaa cgatattgat aaccgctcta aaaataagcg accaaacaac
    25261 ttaccaaatc caagtataag taatagtgat acaaactata ttcatacatt ggagaataaa
    25321 ctggatgcgg ttattaattg tttggttagt ttggttgagt ctaatcaagt tattgcagat
    25381 aaggattacg aaccagttat taataagtat gtgtttgaag atgaggtaaa taattctatc
    25441 gataaacgag agcgtcacga atctacaaga gttagattta gaagaggagg cacgataatc
    25501 taatgcaaga tacaattcaa atagacaata aaacaattgg atggctggtt gtgcaaagag
    25561 ggttcgagat accctctttt aattttgtta ctgaaaaaga aaacgtaaaa ggtagagcgg
    25621 gatctattgt taagaatcgt tatttaaatg atatcgaatt tgatttacca ttaattattc
    25681 gaaacgaaaa attgtcacca ggtggagaaa aaacacacga tgatatatta gaagcattgg
    25741 tcaagttctt caatattaaa gatttaacac ctaaaaaact taaattcaaa tctcaaaact
    25801 ggtattggtt tgcatatttt gatggtccat taaaattacc gaaaaaccca agaggttcag
    25861 tgaagttcac tataaaagta gtgttaacag atccttataa atactcggta actggaaaca
    25921 aaaacac
//
LOCUS       DAPSKH010000039        25762 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPSKH010000039 DAPSKH010000000
VERSION     DAPSKH010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 25762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25762
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.039"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            227..2167
                     /gene="ltaS"
                     /locus_tag="RPH49_001709"
     CDS             227..2167
                     /gene="ltaS"
                     /locus_tag="RPH49_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyglycerol-phosphate lipoteichoic acid
                     synthase LtaS"
                     /protein_id="HDY5124851.1"
                     /translation="MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNL
                     ILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFST
                     LNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMA
                     ASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALAS
                     EDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLN
                     KLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAI
                     LDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFF
                     KDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDE
                     ALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGF
                     WIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGD
                     FITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNP
                     DFKKVNPSKYKYETGPKANSKK"
     gene            2438..4321
                     /locus_tag="RPH49_001710"
     CDS             2438..4321
                     /locus_tag="RPH49_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDY5124852.1"
                     /translation="MGMEAYKIEHLNKSYADKIIFDNLDLSISEGEKIGLVGINGTGK
                     STLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQ
                     YEQAVQAYADDQSDKLFKRMMDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKEL
                     SGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYF
                     LNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAG
                     AKARATKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKV
                     LFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKIAYFKQTD
                     ETLDRDIRMIDYLREESEIAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKR
                     LYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQS
                     YWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSSTTVRKKNGLSYKEKLEYE
                     QLMKRIEQSEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIK
                     EQQ"
     gene            4333..6114
                     /gene="recQ"
                     /locus_tag="RPH49_001711"
     CDS             4333..6114
                     /gene="recQ"
                     /locus_tag="RPH49_001711"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDY5124853.1"
                     /translation="MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSI
                     CYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQHIEKELTS
                     GNIQFLYVAPERFENRYFLNLLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFM
                     LPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFIL
                     DYIKTHDEDAGIIYCSTRKQVEELQEALESQNIESVIYHAGLSNKEREEAQNDFLFDR
                     VKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERD
                     INLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQC
                     SNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTH
                     GLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATE
                     KVFINTVEGVDRALFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMIN
                     IDGVGSYKLKHYCPAFLETIQNYKAKV"
     gene            6335..7312
                     /locus_tag="RPH49_001712"
     CDS             6335..7312
                     /locus_tag="RPH49_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124854.1"
                     /translation="MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTL
                     KMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQM
                     KKWKEKDIDKRVDELLEMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMD
                     EPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQID
                     TPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYD
                     NQPIEVLYQLLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD"
     gene            7305..8819
                     /locus_tag="RPH49_001713"
     CDS             7305..8819
                     /locus_tag="RPH49_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDY5124855.1"
                     /translation="MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILL
                     TKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYT
                     GIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIG
                     AGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVM
                     IIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAF
                     LFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMK
                     YNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNL
                     DNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKE
                     SFLKKHPEIKKPLNKLENKISDEDMQVMNYKVTVKNEDPYTVAKDYLKAKGLIK"
     gene            9059..10114
                     /gene="hisC"
                     /locus_tag="RPH49_001714"
     CDS             9059..10114
                     /gene="hisC"
                     /locus_tag="RPH49_001714"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDY5124856.1"
                     /translation="MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSP
                     KVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLT
                     PGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPN
                     NPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRT
                     FSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHK
                     NSVERERFYQLPQSEHFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIG
                     FKEQNDKMLEVLSNFKY"
     gene            10275..10817
                     /locus_tag="RPH49_001715"
     CDS             10275..10817
                     /locus_tag="RPH49_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'(3')-deoxyribonucleotidase"
                     /protein_id="HDY5124857.1"
                     /translation="MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLK
                     HVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDK
                     YEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDR
                     FERVNGWKDVEQYFLDNIEK"
     gene            complement(11210..12127)
                     /locus_tag="RPH49_001716"
     CDS             complement(11210..12127)
                     /locus_tag="RPH49_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDY5124858.1"
                     /translation="MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLS
                     ESEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMAHNLQLPIGILPGGTF
                     NDFTKTLNIAPNHKQASEQMISAQVGTYDVIKVNNQYALNFVGLGLIVQNAENVQDGS
                     KDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTD
                     LSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKV
                     DIDGEISLETPIDIEVIPNAIQLLTVNDL"
     gene            12218..12319
                     /locus_tag="RPH49_001717"
     CDS             12218..12319
                     /locus_tag="RPH49_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124859.1"
                     /translation="MVINEINLYRVGRENIVIAVYNEHIKFLFILIT"
     gene            complement(12397..13902)
                     /locus_tag="RPH49_001718"
     CDS             complement(12397..13902)
                     /locus_tag="RPH49_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDY5124860.1"
                     /translation="MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMR
                     ALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLG
                     AVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFV
                     IFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMK
                     PTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYF
                     TLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGW
                     KTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGI
                     VGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNA
                     SAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR"
     gene            complement(14240..14740)
                     /gene="queF"
                     /locus_tag="RPH49_001719"
     CDS             complement(14240..14740)
                     /gene="queF"
                     /locus_tag="RPH49_001719"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDY5124861.1"
                     /translation="MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDY
                     FVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCM
                     NIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYP
                     EKIDNR"
     gene            complement(14760..15626)
                     /locus_tag="RPH49_001720"
     CDS             complement(14760..15626)
                     /locus_tag="RPH49_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001594836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDY5124862.1"
                     /translation="MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVA
                     MFIPLFFIYKYHQPMFGKLSSQPLLLTRSTLGLIGVLLNIYAIDHMVLSDADSLMKLN
                     PFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAAS
                     AYTCVRALSTREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVG
                     QIGVTLAYSFAAAKDISIFTYASIIFTAILGFILFGESPDFYATLGYVVIIGASYYMF
                     EKARRDAKIIKK"
     gene            16427..16825
                     /gene="nrdI"
                     /locus_tag="RPH49_001721"
     CDS             16427..16825
                     /gene="nrdI"
                     /locus_tag="RPH49_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDY5124863.1"
                     /translation="MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVT
                     GTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFE
                     LHGKNKDVIEFKNKVGNFNENHGREKVQSY"
     gene            16788..18893
                     /gene="nrdE"
                     /locus_tag="RPH49_001722"
     CDS             16788..18893
                     /gene="nrdE"
                     /locus_tag="RPH49_001722"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000855513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDY5124864.1"
                     /translation="MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVK
                     DKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSIPFNFASYMSASKFF
                     KDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNA
                     GRVRRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIK
                     GVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRL
                     STISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVE
                     KKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQET
                     SIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAP
                     GVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIA
                     KERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMVIPTSEDWKKLQQDV
                     EQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTM
                     WYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKS
                     LYYTRNKLLSVEECTSCSI"
     gene            19013..19984
                     /gene="nrdF"
                     /locus_tag="RPH49_001723"
     CDS             19013..19984
                     /gene="nrdF"
                     /locus_tag="RPH49_001723"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDY5124865.1"
                     /translation="MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSE
                     AEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHI
                     FTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFL
                     ETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEK
                     QKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEE
                     REFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK"
     gene            20354..21325
                     /locus_tag="RPH49_001724"
     CDS             20354..21325
                     /locus_tag="RPH49_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124866.1"
                     /translation="MKYLLKGKILLLLLILLTIISLFIGVSELSIKDIFHLSDSQQNI
                     LFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFP
                     TGHILLKLVFAVICSIGGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLR
                     TNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGL
                     SYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGA
                     IFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ"
     gene            21312..22268
                     /locus_tag="RPH49_001725"
     CDS             21312..22268
                     /locus_tag="RPH49_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDY5124867.1"
                     /translation="MRNNNKKIMLLIVVTFLISMLYLFVGIDFEIFEYQFSSRLRKFI
                     LIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVY
                     LNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPES
                     FLAIQSSMFANFNASNSNLVSFSAVLLVILLVITIFLLPYLDVLLLGRAEAINLGISY
                     EKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWI
                     SLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ"
     gene            22265..23026
                     /locus_tag="RPH49_001726"
     CDS             22265..23026
                     /locus_tag="RPH49_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124868.1"
                     /translation="MIQVGNLTKTINNQMILDDISIEIEKGKLTSLIGPNGAGKSTLL
                     SAICRLIRFDEGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFP
                     YSKGRLTKEDHEIVNDALDLLQLQDIRKRNIKSLSGGQRQRAYIAMTIAQDTEYILLD
                     EPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSD
                     LKDNVIQSSVLSDLYDMDIQIEHIKNQRICLYFKD"
     gene            23145..24173
                     /locus_tag="RPH49_001727"
     CDS             23145..24173
                     /locus_tag="RPH49_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5124869.1"
                     /translation="MKKTVLYLVVAVMFLLAACGNNSDKEQSKSETKGSKDTVKIENN
                     YKMRGEKKDGSDAKKVKETVEVPKNPKNAVVLDYGALDVMKEMGLSDKVKALPKGEGG
                     KSLPNFLESFKDDKYTNVGNLKEVNFDKIAATKPEVIFISGRTANQKNLDEFKKAAPK
                     AKIVYVGADEKNLIGSMKQNTENIGKIYDKEDKAKELNKDLDNKIASMKDKTKKFNKS
                     VMYLLVNEGELSTYGPKGRFGGLVYDTLGFNAVDKKVSNSNHGQNVSNEYINKENPDV
                     ILAMDRGQAVSGKSTAKQALNNPVLKNVKAIKEDKVYNLDPKLWYFAAGSTTTTIKQI
                     EELEKVVK"
     gene            complement(24490..24804)
                     /locus_tag="RPH49_001728"
     CDS             complement(24490..24804)
                     /locus_tag="RPH49_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124870.1"
                     /translation="MPIVYGSLIDTETRCRHYFTEEDIIAIKFKCCNKYYPCYKCHNE
                     FEKHAIKRWSEPSFNEKAILCGVCKHELTINEYMMVERCPNCQSRFNNRCKYHYHIYF
                     EI"
     gene            complement(24822..25745)
                     /locus_tag="RPH49_001729"
     CDS             complement(24822..25745)
                     /locus_tag="RPH49_001729"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDY5124871.1"
                     /translation="MINKDIYQALQQLIPNEKIKVDEPLKRYTYTKTGGNADFYITPT
                     KNEEVQAVVKYAYQNEIPVTYLGNGSNIIIREGGIRGIVISLLSLDHIEVSDDAIIAG
                     SGAAIIDVSRVARDYALTGLEFACGIPGSIGGAVYMNAGAYGGEVKDCIDYALCVNEQ
                     GSLIKLTTKELELDYRNSIIQKEHLVVLEAAFTLAPGKMTEIQAKMDDLTERRESKQP
                     LEYPSCGSVFQRPPGHFAGKLIQDSNLQGHRIGGVEVSTKHAGFMVNVDNGTATDYEN
                     LIHYVQKTVKEKFGIELNREVRIIGEHPKES"
BASE COUNT         9348 a         3656 c         4471 g         8287 t
ORIGIN      
        1 aaagaaactt acacaagcaa atatgagttg tagcccaaaa tacttgttaa atcaaagttg
       61 aaagctacaa ataatgaaat ttataaactt gaatctgaaa gtaattacta taattatgac
      121 aatgttaact tttaaacgca cttattaatt aactacataa tgttaatatc taatttattc
      181 aagtactttc gcaagattta ttatctaaat aacgggggaa agaatcatga gttcacaaaa
      241 aaagaaaatt agtctttttg cgttcttctt attaaccgta ataacgatta ccttgaagac
      301 gtatttttct tattatgttg atttttcttt aggtgttaaa ggtttagtac aaaacttaat
      361 attattgatg aatccttata gtttagtagc actggtttta agtgtgttcc tattctttaa
      421 aggcaaaaaa gcattttggt tcatgttcat aggcggcttc ttattgacgt tcctattata
      481 tgccaatgtt gtgtacttta gattcttctc tgatttttta acgtttagta ctttaaacca
      541 agtaggtaac gtagaatcta tgggtggtgc ggttagtgca tcattcaaat ggtatgactt
      601 tgtttatttc attgatacgt tagtttactt attcatttta atatttaaaa caaaatggtt
      661 agacacaaaa gcatttagta agaaatttgt tcctgtcgta atggcggctt cagtagcatt
      721 attcttctta aacttagctt ttgctgaaac tgacagacca gaattattaa cacgtacatt
      781 tgaccataaa tatttagtga aatatttagg gccttataac tttacagttt acgatggtgt
      841 taaaactatc gaaaataatc aacaaaaggc gttagcatct gaagatgact taacaaaagt
      901 attaaattat acgaagcaac gtcaaacaga gcctaaccca gaatattatg gggtggcaaa
      961 gaagaaaaat attattaaga ttcatttaga aagtttccaa accttcttaa ttaataaaaa
     1021 ggttaatggt aaagaagtaa caccgttttt aaacaaatta tcaagtggga aagagcaatt
     1081 cacatatttc cctaactttt tccatcaaac aggtcaaggt aaaacatctg actctgaatt
     1141 tacaatggat aacagtttat acggcttacc gcaaggttct gccttttcat taaaaggaga
     1201 taatacgtat cagtcattac cagcaatttt agatcaaaag caaggttaca aatctgatgt
     1261 tatgcacggt gactataaaa cattctggaa cagagaccaa gtatataaac actttggtat
     1321 cgataaattc tatgatgcaa catactatga catgtctgat aaaaacgttg taaacttagg
     1381 cttgaaagac aaaatcttct ttaaagattc tgctaattat caagctaaga tgaaatcacc
     1441 attctattct catttaatta cattgactaa ccactatcca ttcacattag atgaaaagga
     1501 tgcaactatt gagaagtcaa acacaggtga tgcaacagtt gatggttata ttcaaacagc
     1561 acgttattta gacgaagcat tagaagaata tattaatgac ttgaagaaaa aaggattata
     1621 tgacaattca gtgattatga tttatggtga ccactatggt atctctgaaa accataacaa
     1681 tgccatggaa aaactattag gtgaaaaaat cacaccagct aaatttacag atttaaacag
     1741 aactggtttc tggattaaaa tccctggtaa atctggtggt atcaataatg aatatgctgg
     1801 tcaagtcgat gtaatgccaa caattttaca tttggctggt atagatacga agaattattt
     1861 aatgttcggt actgatttat tctctaaagg tcataatcaa gtagttccat tcagaaatgg
     1921 tgactttata acaaaagatt ataaatatgt taatggtaag atttattcta ataaaaataa
     1981 tgaactcata actactcaac cagctgattt cgaaaagaat aaaaagcaag ttgaaaagga
     2041 tctcgaaatg agtgacaacg tgcttaatgg tgatttgttt agattctaca aaaatccaga
     2101 cttcaaaaag gtaaatcctt cgaagtataa atatgaaaca ggacctaaag caaactctaa
     2161 aaaataatat ttaaacacga actcggattg ataaaatatc aatccgggtt tttattatgt
     2221 tcttttatat tatgttttac attatatgtg ttgataaaaa ggtatattat aaagatcatt
     2281 agcatagtca tcaaagcctt atcaaatttt atttatagtt gaagcaacaa tttattaaat
     2341 tatgacactt aacagtatcg atttcttttg atttcaaaaa ggtgtataat gtatagaact
     2401 gatttaagta cgtagagatt tcaacagaag aaggaagatg ggtatggaag catataaaat
     2461 tgaacattta aataaatctt atgccgataa gattatattc gataatctag atttatcaat
     2521 ttcagaaggt gaaaaaatag gtttagtagg cataaatggt acagggaaaa gtacattgtt
     2581 aaaagtaatt ggtggtattg atgatgattt tacagccaat gttatgcatc caaatcaata
     2641 tcgaattcgt tattcgtctc agaaacagga tcttaatgaa gatatgactg tttttgatgc
     2701 agtattaagt tctgatacaa caactttacg catcatcaag caatatgagc aggcagtaca
     2761 agcttatgcg gatgaccaaa gtgataaatt gttcaagcga atgatggatg cgcaagatgc
     2821 tatggatcaa catgatgctt gggactataa cgctgaaatt aaaacaatcc tctcaaaact
     2881 aggtatacat gatactacta aatacattaa agaattatcc ggcggacaac aaaaacgtgt
     2941 tgtacttgct aaaacattaa tagaacaacc agatttattg ttattagatg aacctacgaa
     3001 ccatttagac ttcgaatcaa tcagctggtt gatcaattat gtgaagcaat atcctcatac
     3061 agttttattc gtaacccatg atcgatattt tttaaatgaa gtttccacta gaattattga
     3121 actaaacaga ggtaagttag cgtcatatcc tggtaactat gaatcttata ttgaaatgcg
     3181 cgctgaaaga gaagtaacac ttcaaaagca acaacaaaag caacgagctt tatataagga
     3241 agaacttgct tggatgaggg ctggagctaa ggctcgtgct acaaagcaac aagctagaat
     3301 taatcgattt aatgacctag aaaatgaagt taaccagcaa tataaagacg ataaaggtga
     3361 attgaatctt gcttattcaa gattaggtaa gcaagtgttc gaattagaag acttatcaaa
     3421 ggctattaat gataaagtat tatttgaaca tctaacggaa attattcaaa aaggtgagcg
     3481 tattggtgtt gttggtccaa atggagctgg taaaacaaca ctcttaaata ttttgagtgg
     3541 agaagaccaa caattcgaag gtaaattgaa gactgggcag acggttaaaa tagcttattt
     3601 taagcaaaca gatgagacct tggatagaga tattcgtatg atagattatt taagagaaga
     3661 aagtgagatt gcaaaagaaa aagatggaac ctcggtatct attacacaac ttcttgaacg
     3721 atttttattt ccaagtgcaa ctcatggtaa aaaagtttat aaattatctg gtggagagca
     3781 aaagcgtttg tatttattac gtctactcgt acaccagcca aatgttctgt tgttagatga
     3841 accgacaaat gatttagata ccgagacttt aacaatactt gaagattata ttcatacttt
     3901 cggtggtaca gtgattaccg taagccatga tcgttacttc ttaaataaag ttgcacagtc
     3961 atattggttt attcatgatg gtcagatgga aaagattatc ggaacttttg aagattatga
     4021 aagttataaa aaatcattag ataaaaataa atccacattg aagcaacaat ctaaatcttc
     4081 tacaactgta cgtaagaaaa atgggttatc atataaagaa aaattagaat atgaacaatt
     4141 gatgaaacgt atagaacaat cggaagtaag aatggaagaa attgatgtgc tcatgattga
     4201 ggcaagtgca gattatggga aaattaaaga attaaacgaa gaaaaagaac aacttgaaat
     4261 tcaatatgat ttagacatca caagatggag tgagttagaa gaaattaaag aacaacaata
     4321 aggggtcaat ttatgatgca acaaacatta tcgcattact ttgggtatga aacgtttcga
     4381 ccaggacaag aagaaattat tagcaaagta ttagaccatc gtaatgtgct tggtgtctta
     4441 ccaactggtg ggggtaagtc tatatgctat caagtaccag gtttattgtt aggtggtaca
     4501 acgattgtta taagtccact aatttcatta atgaaagatc aagtggatca attaaaggca
     4561 atggggattc aagctgcttt tttaaacagt agtttgactc aaaaagaaca acaacatatt
     4621 gaaaaagaat taacaagtgg gaatattcaa tttttatatg ttgcaccaga acgatttgaa
     4681 aatcgatatt ttttaaattt gcttcaacgt atcaagattc atttagtggc gtttgatgaa
     4741 gcgcattgta tatctaaatg gggacatgat ttcaggccga gttaccaaaa tgttatttca
     4801 aaagtgttta tgttaccaca agattttaca attattgcat tgacagcaac tgcaacagtt
     4861 gaagtacagc aagatattag agaaaagtta aatatcgctc aaactgatca aattaaaacg
     4921 agtactaagc gtagaaactt aatttttaaa gtaaatccta cttatcaacg tcaaaaattt
     4981 atattggatt atattaaaac acacgatgaa gatgcaggta ttatttattg ttctacacgt
     5041 aagcaagttg aagagcttca agaagcctta gaaagccaga acattgaaag tgttatatat
     5101 catgcaggtt tgagcaataa agaaagagaa gaagcgcaga atgatttctt atttgatcgt
     5161 gttaaagtag tcgttgctac aaatgctttt ggtatgggta ttgataaatc caatgtacgc
     5221 tttgttattc attataatat gcctggagat ttagaatctt attatcaaga agcgggtcgt
     5281 gcaggtcgtg acgggttgaa aagtgaatgt attttgttat ttagcgaacg cgatatcaat
     5341 ttacacgagt attttataac agtctctcaa gctgatgatg actataaaga taaaatgggt
     5401 gaaaagttaa ctaaaatgat tcaatataca aaaacaaaaa aatgtttaga agcaacaatt
     5461 gtccattatt ttgaaccgaa tgaaaaatta gaagaatgtg aacaatgtag taattgtgtt
     5521 caacaagata aatcatataa tatgacacaa gaagctaaga tgattattag ttgcatcgct
     5581 cgtatgaaac aacaagagag ttatagtgtt atcatccaag tattaagagg agagtcaaca
     5641 gattatatta agtataaagg ttatgaccaa atttcaaccc atggtttaat gaaaggttac
     5701 acaacatcag aattaagtca cttaatagat gaattaagat tcaaagggtt cttaaatgaa
     5761 aatgatgaaa tattaatgtg tgatacttca attaaaaaat tactcagtaa tgaagtagaa
     5821 gtattcacaa caccatttaa gcaaaaagcg actgaaaaag tatttataaa tacggttgaa
     5881 ggggttgacc gagcattatt cagccagttg gtagaagttc gtaaaaagtt aagtgacaaa
     5941 ttaacgatag cacctgtaag tatattttct gattacacgc tagaggaatt tgctaaacgt
     6001 aagcctgctt cgaaacaaga tatgattaat attgatggcg taggtagtta caaattaaaa
     6061 cattattgtc cagcattttt agaaacgatt caaaattata aagccaaagt atagtgaagg
     6121 cacctagtaa acattccttg ttttactggg tgttttttga attcaaagta aaataacact
     6181 atttcttaac tggagattac ctattattca ttattttgtt aaaaaagttc aaggataaat
     6241 catttaaatt tgaaaattgt aataaacgtg gttaaatagg gaatacatac atataatctc
     6301 ggttttatgc tatgagaaaa aaagaggtgg caaagtgatt aagtttaaaa atgtaactaa
     6361 gcgttatggc aaacatgttg ctgtcgataa cattagtttc aatattaatg agggtgaatt
     6421 ttttgtgctc attggacctt caggttgtgg aaaaactacg acattaaaaa tgattaatcg
     6481 actcattcac ttaagtgaag gttatattta ctttaaagat aaaccaataa gtgattatcc
     6541 agtatacgaa atgcgttggg atattggata cgtattgcag cagattgcat tattcccaca
     6601 tatgacaatc aaagaaaata ttgcacaagt gccacaaatg aaaaagtgga aagaaaaaga
     6661 tatagataaa agagtagatg aattacttga aatggttgga ttagaacctg aaaaatataa
     6721 aaacagaaaa cctgatgaat tgtcaggggg gcaacgacaa cgtgtaggag ttatacgtgc
     6781 gttagcagct gatccaccag ttattttaat ggatgaaccg tttagtgcat tagacccaat
     6841 cagccgagaa aaacttcaag atgatttaat tgaattacaa actaaaatta agaagacaat
     6901 catatttgtt acacatgata ttcaagaggc gatgaaactt ggtgataaga tttgtctttt
     6961 gaatgaaggg catattgaac aaattgacac accagaagga tttaaaaata atcctcaaag
     7021 tgaatttgtt aaacaattta tgggtagtca tttagaagat gatgcgccat gtgttgaaga
     7081 gaacgcaatt atccgtgact tggatattat gaaaccaatc gatgaggtta catctatgag
     7141 cgcttatcca attgtttatg acaatcaacc aattgaagta ttgtatcaac ttttatcaga
     7201 gagcgagcgt gtcattgtca tgcaagaaga tagcgtaggt caatatgtta ttgataggaa
     7261 agatatcttc aaatatttgt cccagaaaaa ggaggtagct caacatgact aactttttcg
     7321 acatattgag tgaacgtaag ggacaactct tttcgacaat gatagaacat attcaaatat
     7381 catttatcgc attattgatt gcaactgcta ttgcggtacc attaggtatt ttattaacga
     7441 agactaaaac gatatctgaa atcgtaatga atattgcggc aattcttcaa accataccat
     7501 cgttggcatt attaggttta atgattcctt tatttggtat cggtcgtgtg ccagcaatta
     7561 tcgcacttgt agtgtatgcg ttgttaccaa ttttaaggaa tacgtatact ggaattaaag
     7621 aagttgatcc atcactcatt gaagcggcta aaggtatagg tatgaaacca tttagacgtt
     7681 taactaaagt cgaacttccg atagcaatgc ctgttataat ggctggtgta agaacggcta
     7741 tggtattaat tataggtaca gcaacactag cagcattaat tggtgcaggc ggactaggag
     7801 atttaatttt attaggtata gaccgtaaca atgcatcatt gatattatta ggtgcaattc
     7861 cagcagcctt attggcaatt atatttgatt taattttaag atttatggct aaattatctt
     7921 ataaaaagtt attgatgacg ttaggtgtta tagtgatgat tattatactg gctatcgcta
     7981 ttcctatgtt tgcacaaaaa ggtgataaaa ttacgttagc tggaaagctt ggctccgagc
     8041 cttcgattat tacaaatatg tataaaattt taatagaaga agagaccaaa aatactgtag
     8101 aagtgaaaga tggtatgggg aaaacagcat ttttatttaa tgctttaaaa tctgatgata
     8161 tagatgggta tttagagttt actggaacag ttttaggtga attaacaaaa gaaccattga
     8221 agtcaaaaga agagaaaaaa gtttatgaac aagctaagca aagtcttgaa aagaaatatc
     8281 aaatgactat gttaaaacca atgaagtata acaatacgta tgctttagct gtaaaacgtg
     8341 attttgctaa acaacataat atacgtacaa ttggtgattt aaataaggtt aaagatcaac
     8401 ttaaaccagg atttacattg gaatttaatg atcgtccaga tggttacaaa gctgttcaaa
     8461 aggcttataa tttaaattta gataacatac gtacaatgga acctaagttg agatatcaag
     8521 cgatcaataa aggtaatatt aatttaatag atgcatattc aactgacgct gaattaaaac
     8581 aatatgatat ggttgtgtta aaagatgata agcacgtatt tccaccatat caaggagcac
     8641 cattatttaa agaaagcttt ttaaagaaac atccagaaat taagaaaccg ttaaacaaat
     8701 tagaaaacaa aatatctgat gaagatatgc aagtgatgaa ctataaagta acagttaaaa
     8761 atgaagaccc atatacagtt gcgaaagatt atttaaaagc aaaagggtta atcaaataac
     8821 gaccaacgcc acataagatg aggggcacgc cattatatct tatgtggcgt tgctatattt
     8881 acatctatgt ttatgtacaa tttaaacata caatattaat aattgaattt gttatgctaa
     8941 ttactattta cattagtaat gtatgaaaat agtagcattg cattttagaa acatagagcg
     9001 atataatgaa tataagtttt ttaaaatttc agttaattct aaggaggttg tttttattat
     9061 gaaagaacaa cttaatcaac tatcagcata tcagcctggt ttatctccaa gggcattgaa
     9121 agaaaagtat ggcattgaag gagatttata taaacttgca tcaaatgaaa atttgtatgg
     9181 accatcgcca aaagttaaag aagcgatatc agcacactta gatgagttat attattatcc
     9241 tgaaacagga tcaccgacat taaaagcggc gattagtaaa catttaaatg tagatcaatc
     9301 acgcatttta tttggtgcgg gattagatga agttatatta atgatttcta gagctgtatt
     9361 aacgccaggg gatactattg ttacaagtga agcgacattc ggtcaatatt atcacaatgc
     9421 gattgttgaa tcagctaatg tgatacaagt acctttaaaa gatggtggct tcgatttaga
     9481 aggtatttta aaagaagtta atgaagatac gtcattggta tggttatgta atccaaataa
     9541 tcctacaggt acatatttta atcatgagag cttagattcg tttttatctc aagtacctcc
     9601 acatgtacca gtaattatag atgaagctta ttttgaattt gtgacagcag aggactaccc
     9661 ggatacactt gctttgcaac aaaaatatga caatgctttc ttattacgta cattttcaaa
     9721 ggcgtatgga ttagcgggtt tacgtgtagg atatgtggta gcaagtgaac atgcgattga
     9781 aaaatggaac atcattagac caccatttaa tgtgacacgt atatctgaat acgcagcagt
     9841 tgcagcactt gaagatcaac aatatttaaa agaggtaaca cataaaaata gtgttgaacg
     9901 cgaaagattt tatcaattac ctcaaagtga gcatttctta ccaagtcaaa cgaattttat
     9961 atttgtaaaa acaaagcggg taaatgaact ttatgaagcg cttttaaatg tagggtgtat
    10021 tacgcgacca tttccaactg gtgttagaat tacaattggt tttaaagaac aaaatgataa
    10081 aatgctagaa gttttatcaa actttaaata ctaatagaaa agggcaccac atggtatgaa
    10141 tatgtgccaa aatgcagtgt gaattatgag gtgagagcat ttattgtaaa aagcaacaat
    10201 agatgatatt gttttgtatc aattgctttt ttgctatact gaattaatac tgatattttg
    10261 aggagaagat taaaatgacc cgtaaatcaa tcgcgattga tatggatgaa gtattggcag
    10321 atacattagg agaaatcatt gatgctgtca attttagagc ggatttaggt attaaaatgg
    10381 aagctttgaa tggtcaaaaa cttaaacatg ttattcctga acatgatgga ttaattacag
    10441 aagtattgag agaaccaggc ttcttcagac atcttaaagt gatgccgcat gcacaagaag
    10501 ttgtaaaaaa attaactgaa cattatgatg tatatattgc tacagcagca atggatgtac
    10561 caacatcatt tagtgataaa tatgaatggt tactagagtt ctttccattc ttagatccac
    10621 agcattttgt tttttgtggt agaaaaaaca ttgttaaagc tgattattta atagatgaca
    10681 atcctagaca gcttgaaatt tttactggta caccgattat gtttacagca gtgcataata
    10741 ttaatgatga tcgatttgaa cgcgtaaatg gttggaaaga tgtagaacag tattttttag
    10801 ataatattga gaaataaaaa tatatcactt gaagcatttt atgtagcaaa gatgatggat
    10861 atactattat gaagttggga ctggacgacg aaataaattt tgcgaaaata tcatttccgt
    10921 cccgctctca ataaatgtta gtctatctca ttattataaa tcggatgaat gtgtaaatct
    10981 atggcagatt acacgtcatc cgatttttta taggatttga aaaaggcgca taaaccacta
    11041 tgatttaaaa tacaacatca atcattttag tggcatgcgc caaaattata tgtctgtttt
    11101 tgaaacaggg taatagctta aagctaataa aaacgaatat aaggtgcgtt gaatcttatg
    11161 attacactct aaacctaata taatatcccg ttaagatcat tccggatgct tacaaatcat
    11221 tgacagtaag taactgaatg gcatttggta taacctcaat atcaataggt gtttctaatg
    11281 aaatttcgcc atcaatatca actttcattg ctggatctgt tgtaagtgaa atctttttac
    11341 caggtatatg ctcaatacct tgagtaattt cattccaatt catgctatca cgctttttaa
    11401 aaatatcatt taaaatactg aaactttgtt cattaaaaat gaaagtgttc agttcaccat
    11461 cttgaggaga caaatcagtc aatggtatac gactaccacc aatgaatgga ccatttgctg
    11521 taagtatcat ggtcgtttcg ccagaatatg tcttatcatc aattgataat tgataattaa
    11581 attgtgttgg atttagcagt gttttaacag ttgatccaat ataacttaat ttaccaaata
    11641 tatcttttga cccatcttgt acgttttcag cgttttgaac aattagacct aagccaacaa
    11701 agttgagtgc atattgatta tttactttta ttacatcgta tgtaccaact tgtgcagaaa
    11761 tcatttgttc actagcttgt ttatgattag gtgcaatatt tagcgttttt gtaaaatcat
    11821 taaaagtacc gcctggtaaa atgccgatag ggagttgaag attatgtgcc ataacaccat
    11881 ttataagttc gttaaccgtg ccatcaccgc caagaataaa taatatatct acatcttttg
    11941 catagttttt agttttgatt tcttggcaat atttaataat gtcaccttcg ctttcactca
    12001 attgaataga aagatgctta caaattgaac ttaatgctgt tgtaacttcc ccaatacctt
    12061 gattaatatt ttttaatcca ctgtgttcat ggtaaaagag gacaccatgt gtatatttgt
    12121 tttccatagt ttagcctact ttctaaaaat tggttcatta aatatatata cccactttta
    12181 attgctaata ccaaaaatat gtttttaaat agagaaaatg gtaataaatg aaattaatct
    12241 ctatagagtg ggacgagaaa atatagttat agctgtctat aatgagcata ttaagttttt
    12301 atttatactg ataacttgaa tttaattaat ggaaacctat aaaaaaacag taagccattt
    12361 aaatgactta ctgtttttta atttaggtca acaatattaa cgaatacctt tcattgcttt
    12421 aataattaaa ggtgagaatg ctaatacaat tgttgtaaca ataattgcaa caacacctaa
    12481 gaaaataaag taatttgttt gacctagtgg ttctattaac ttaactaatg taccattgat
    12541 tgcttgtgca gaagcgttag ttaagtacca aatactcatc atttgggcat taaatgcttt
    12601 aggtgctaac ttaacagcag cactattacc cgttggtgat aagcatagct caccgataac
    12661 acaaataatg tacgataaaa taacccagtt aactgagaag tttgatgaac ctgatgcata
    12721 acctacaata ccaattagta tgtatgacgc acctgctaag aacgtaccaa ttgcaaattt
    12781 tactggcagg ctaggttgtt tagttccaag cttttgccat aaaagtgaaa taattggagc
    12841 taataataaa ataaataatg ggttaattga ttggaagatc gcttcaccaa agtttgtttt
    12901 ccaaccaaat aagtttaatt tcatatctga atgttcaatt ccataaatgt ttaatacatt
    12961 agacccttgt tcttgaatag cccagaacac cattccaaga ataaataatg gaataaatgc
    13021 tttaacacga gaacgttcag tatcagtgac atctttactt ctaataatta aagtgaagta
    13081 aatgattggt aatgcaatac ctaatactaa aacagtatta ctaactaagt taaatgataa
    13141 tgagttagtt aatgcaccaa taacgataat taatacaatt gctaagacaa cacttccgat
    13201 aataagacca tactttttct tttcagctgg tgtcaatggg ttagtaggtt tcataccaac
    13261 gctacctaag tttttgcggt tgaaaagtac ataccatact aaacctaatg ccataccaac
    13321 tgctgcaatc aagaatccgc cgtggaagtt tttaacatta acaaagtgtt gcaaaataat
    13381 aggtgataat aatgcaccca tattaactga catatagaaa ataacaaaac ctgcatccat
    13441 acgtctatca ttttcaggat ataaacggcc aacgatattt gaaatatttg gcttcattaa
    13501 acctgaacca ataatgatga agaacattga tgtgaataag ccgattaatg caaatggtaa
    13561 gcttaaacaa atatgtccga taataataaa gactgcacct aataaagtag cgcctctagt
    13621 acctgtaatt ctgtcagcaa tccatccgcc tggtattgat gtcatataga ttaatgaacc
    13681 ataaactgac ataattgaca tagctgttgt tttatcaatt ccaaggccat tatctgttac
    13741 ggcaaagtac atgtagaaaa tgagtagggc acgcatgcca taataactaa acctttccca
    13801 gaactctaca aagaagagta cacctagtcc tcgaggatgc ccgaaaaatc ctgtttgagg
    13861 tatgtcttga atttgatttc catgggagtt ttgttgtgtc atttatacat cccatccttt
    13921 cttcccctaa tacaatagtt taagtaaatt tgattgtacc ttatcaacta aatattccaa
    13981 taaatcacaa aaaaataaaa atattgagaa tattctgtta ttaagcgcgc acaattaatt
    14041 agagataata taaaaatata cttattgacg ttaaagtgca ataggtttct ataaaaatgt
    14101 tgtttaatta gtgtattaat attcttttgg tgtactttgg gatttaatga ttgaagttaa
    14161 tttacaatat atattaaaaa agcacatcaa caagttggta gtaaccaaca tactgatgtg
    14221 ctttgaaaag ggaaacaaat taacggttat ctattttttc tggatataaa tcatgattca
    14281 ttagacgatg ctcagccatt ttttcatatt tagaatttgg acgtccatag tttgtataag
    14341 ggtcaataga aattccacca cgtggtgtga acttgcccca aacttcaata taatgtggat
    14401 ccataagctc tatcaagtca ttcataataa tattcataca atcttcgtgg aaatcaccgt
    14461 gatttctgaa actaaataag taaagtttca acgattttga ttcaaccatt ttaacatttg
    14521 gaatataaga aatgtagata gttgcaaaat ctggttgccc agtaatcgga cataatgatg
    14581 tgaattctgg acagttgaat tttacgaaat agtcgcgacc ttgatgttta ttatcgaatg
    14641 attctaaaac atcaggacga tagtcaaaat tgtaagtatt gtcttgattt cctaataaag
    14701 ttatatcttg taattcatct tgttgacggc catgtgccat ataaagcgct cctttaaatt
    14761 tattttttta ttattttggc gtctcggcgt gctttttcaa acatgtaata acttgcaccg
    14821 ataataacga cgtaacctaa tgttgcatag aaatctggag attctccaaa tagaataaat
    14881 ccaagtattg ctgtaaaaat tatagatgca tacgtgaaaa tagaaatatc tttagcagca
    14941 gcaaaactat atgccaatgt aacaccaatt tgacccacag cggcagctaa gccagcccct
    15001 aatagataaa gtatttgcat ctgactcatt ggttcatatg tatatgcagt aaatggtatt
    15061 aatacgatga ctgaaaataa tgagaagtaa aatacaatgg tgtatggtgc ttctctagta
    15121 ctaagtgcgc gaacacatgt atatgccgat gctgcaaaaa tacctgaaaa tagtccagct
    15181 agtgatggaa tcatagatga tgaaaattca ggtttcacta ttaaaagcat acctaaaata
    15241 gcaattatca ttgctgttat ttgatacttc cttacctttt catgtaagaa aacaatactt
    15301 aataaaatcg tccagaaagg attgagtttc attaatgaat cggcatcact aagtaccata
    15361 tggtcaatgg cgtaaatatt taataataca cctataagtc caagtgtcga acgtgttaat
    15421 aataatggtt ggcttgagag tttaccaaac attggttgat gatatttata tataaaaaat
    15481 aatggaataa acattgctac taagtttcgt gctaatgatt tttgaaaaac aggaagatca
    15541 cctgcaagtc tgaaaaacac tgacataaaa ctgaaaccaa tagccgaaat taaaatggca
    15601 atgatacctt ttactttagg attcaatttt atcgcctctt ttatataaaa ttaacgtatt
    15661 tatattagca taaaacaaca tattgtgcat aaatagttga aatttactat aaaaagccta
    15721 taatagactg taccgaacaa acgttctgtg tttatttgtc ggaataatag ggcattacac
    15781 ttttatgaat gtttgtgtta ttacataaaa caaatatcaa ttcagtatca agctaataag
    15841 ctttttctta atttctgttg atacaattga gattgacgca gattttaaaa aatcaagtga
    15901 tatctactga aaaaattttt ttaatttgtt caagtttttc taattaagta ttggtgccta
    15961 gttggaacgt tttacgaaca ttcgattaga aaatggcact ttaaatcata gtgtgtctta
    16021 tgtataatga aacacataat atagtgttgg tgaaacaaaa aagacacaat atcttgtgtt
    16081 ttgtatgcaa atgctttatt tatgaagaaa ttacatttaa aagtaattta acacagaaat
    16141 ttaatagtca ttatcaatta atagtcatat ttttagaaaa tgtactgagc aaatggaaga
    16201 tatccaatga tgtaaacact acatatagtg atttttatac attcaaccca tataagctac
    16261 tattttctca aatataaatc tatgcaattg gtttacattt gagaaaataa gtagcttcat
    16321 tatagttaat acaatgctga gataaccata gtaaccatgt tgttaaagca ttttttaatt
    16381 gtaatgacta ctttatttaa aagggttgaa gaaagaaggt gatccaatga aaataatata
    16441 tttttcattt actggaaatg tccgtcgttt cattaagaga acagaacttg aaaatacgct
    16501 tgagattaca gcagaaaatt gtatggaacc agttcatgaa ccgtttatta tcgttactgg
    16561 cactattgga tttggagaag taccagaacc cgttcaatct tttttagaag ttaatcatca
    16621 atacatcaga ggtgtggcag ctagcggtaa tcgaaattgg ggactaaatt tcgcaaaagc
    16681 gggtcgcacg atatcagaag agtataatgt ccctttatta atgaagtttg agttacatgg
    16741 aaaaaacaaa gacgttattg aatttaagaa caaggtgggt aattttaatg aaaaccatgg
    16801 aagagaaaaa gtacaatcat attgaattaa ataatgaggt cactaaacga agagaagatg
    16861 gattctttag tttagaaaaa gaccaagaag ctttagtagc ttatttagaa gaagtaaaag
    16921 ataaaacaat cttcttcgac actgaaatcg aacgtttacg ttatttagta gacaacgatt
    16981 tttatttcaa tgtgtttgat atttatagtg aagcggatct aattgaaatc actgattatg
    17041 caaaatcaat cccgtttaat tttgcaagtt atatgtcagc tagtaaattt ttcaaagatt
    17101 acgctttgaa aacaaatgat aaaagtcaat atttagaaga ctataatcaa cacgttgcaa
    17161 ttgttgcttt atacctagca aatggtaata aagcacaagc taagcaattt atttctgcta
    17221 tggttgaaca aagatatcaa ccagcgacac caacattttt aaacgcaggc cgtgtgcgtc
    17281 gtggtgagct agtgtcatgt ttcttattag aagtggatga cagcttaaat tcaattaact
    17341 ttattgattc aactgcaaaa caattaagca aaattggtgg cggcgtagca attaacttat
    17401 ctaaattgcg tgcacgtggt gaagcgatta aaggaattaa aggcgtagcg aaaggtgttt
    17461 tacctattgc taagtcactt gaaggtggct ttagctatgc agatcaacta ggtcaacgcc
    17521 ctggtgctgg tgctgtgtac ttaaatatct tccattatga tgtagaagaa tttttagata
    17581 ctaaaaaagt aaatgcggat gaagatttac gtttatctac aatatcaact ggtttaattg
    17641 ttccatctaa attcttcgat ttagctaaag aaggtaaaga cttttatatg tttgcacctc
    17701 atacagttaa agaagaatac ggtgttacat tagacgatat tgatttagaa aaatattatg
    17761 atgatatggt tgcaaatcca aatgttgaga aaaagaaaaa gaatgcacgt gaaatgttga
    17821 atttaattgc gcaaacacaa ttacaatcag gctatccata tttaatgttt aaagataatg
    17881 ctaatagagt gcatccgaat tcaaatattg gacaaattaa aatgagtaac ttatgtactg
    17941 aaattttcca attacaagaa acttcaatta ttaacgatta tggtattgaa gacgaaatta
    18001 aacgtgatat ttcttgtaac ttaggttcat taaacattgt aaatgtaatg gaaagcggaa
    18061 aattcagaga ttcagttcac tctggtatgg acgcattaac tgttgtaagt gatgtagcaa
    18121 atattcaaaa tgctccagga gttagaaaag ctaatagtga attacattca gttggtcttg
    18181 gtgtcatgaa tttacacggt tacctagcaa aaaataaaat tggttatgag tcagaagaag
    18241 caaaagattt tgcaaatatc ttctttatga tgatgaattt ctactcaatc gaacgttcaa
    18301 tggaaatcgc taaagagcgt ggtatcaaat atcaagactt tgaaaagtct gattatgcta
    18361 atggcaaata tttcgagttc tatacaactc aagaatttga acctcaattc gaaaaagtac
    18421 gtgaattatt cgacggtatg gttattccta cttctgagga ttggaagaaa ctacaacaag
    18481 atgttgaaca atatggttta tatcatgcat atagattagc tattgctcca acacaaagta
    18541 tttcttatgt tcaaaatgct acaagttctg taatgccaat cgttgatcaa attgaacgtc
    18601 gtacttatgg taatgcggaa acattttacc ctatgccatt cttatcacca caaacaatgt
    18661 ggtactacaa atcagcattc aatactgatc agatgaaatt aatcgattta attgcgacaa
    18721 ttcaaacgca tattgaccaa ggtatctcaa cgatacttta tgttaattct gaaatttcta
    18781 cacgtgagtt agcaagatta tatgtatatg cgcactataa aggattaaaa tcactttact
    18841 atactagaaa taaattatta agtgtagaag aatgtacaag ttgttctatc taacaattaa
    18901 atgttgaaaa tgacaaacag ctaatcatct cgtttaaaat aacagatgat tagtctgcca
    18961 tgtctatatt tgtcaattat tgagagtaac attacaggag gaaattatat tcatgatagc
    19021 tgttaattgg aacacacaag aagatatgac gaatatgttt tggagacaaa atatatctca
    19081 aatgtgggtt gaaacagaat ttaaagtatc aaaagacatt gcaagttgga agactttgtc
    19141 agaagctgaa caagacacat ttaaaaaagc attagctggt ttaacaggct tagatacaca
    19201 tcaagcagat gatggtatgc ctttagtcat gctacatacg actgacttaa gaaaaaaagc
    19261 agtttattca tttatggcga tgatggagca aatacacgcg aaaagttatt cgcatatttt
    19321 cacaacgtta ttaccatcta gtgaaacaaa ctatttatta gatgaatggg ttttagaaga
    19381 accacattta aaatataaat cagataaaat tgttgctaat taccacaaac tttggggtaa
    19441 agaagcttcc atatatgacc aatatatggc cagagttacg agtgtatttt tagaaacatt
    19501 cttattcttc tctggtttct attatccgct atatttagct ggtcaaggga aaatgacgac
    19561 atcaggagaa atcattcgta aaattctttt agatgaatct attcatggtg tgtttactgg
    19621 tttagatgca cagcatttac gaaatgaact atctgaaagt gagaagcaaa aagctgatca
    19681 agaaatgtat aaattgctaa atgacttgta tttaaatgaa gagtcataca caaaaatgtt
    19741 atacgatgat cttggaatca ctgaagatgt gttaaactat gttaaatata atggaaataa
    19801 agcactttca aatttaggtt ttgaacctta ttttgaggaa cgtgaattta acccaatcat
    19861 tgagaatgcc ttagatacaa caactaaaaa ccatgacttc ttctctgtaa aaggtgatgg
    19921 ttatgtatta gcattaaatg tagaagcatt acaagatgat gactttgtat ttgacaacaa
    19981 ataataatta aaattaaaaa gaccttcaca tgaaagggca aagcgatgac attcgcttcc
    20041 gacatgttga aggtcttttc tctatgctta aaaacgtatg cacattttga aaaagtaaaa
    20101 attgcattta atgatgtcaa tgaggctaga aagtatacaa gatattgcat tacaaaaggg
    20161 tgtgctattt tactatatac atctaaaata cacatttaca aaaattgatt tctattttaa
    20221 ttgcaaatat caataaaatc gacaataaat tatttgaaag gctattgaaa tgagtgacaa
    20281 aaaacgatac cattaatgag aaatgttatc aatgataata attatcatta aattaaaggg
    20341 agaaaatttt gtaatgaagt atttattaaa gggaaaaatt ttgcttctat tacttatatt
    20401 gctaacaatc atttcgttgt ttataggtgt cagtgaactg tctattaaag atatctttca
    20461 tttatcagac tcacagcaaa atatattgtt ctcaagccga ataccgagaa cgatgagtat
    20521 tttaattgct ggtagttcat tagctttagc tggcctaatc atgcaacaaa tgatgcaaaa
    20581 taagtttgtt agtccaacta cagctgggac gatggagtgg gcaaaattag gtatcttaat
    20641 tgccttatta ttctttccaa ctggtcatat tttattaaaa ttagtatttg ctgttatttg
    20701 cagcatcggc ggaacatttt tatttgttaa aattattgat tttatcaaag tgaaagatgt
    20761 catctttgta ccactattag ggattatgat gggtggcatt gttgctagtt ttacaacgtt
    20821 tatctcatta cgtacgaacg cagttcaaag cattggtaac tggcttaacg ggaactttgc
    20881 cattatcaca agtggacgtt atgaaatctt gtatttaagt attcctcttt tagcattgac
    20941 atatcttttt gcgaatcatt tcacaattgt aggaatgggt aaagacttta ccaataattt
    21001 aggtttgagt tacgaaaaat taattaacat cgcattgttt attactgcaa ctattacagc
    21061 attggtagtg gtgactgttg gaacattacc gttcttagga ctagtaatac caaatattat
    21121 ttcgatttat agaggcgatc atttaaaaaa tgctatccct catacgatga tgttaggtgc
    21181 catctttgta ttgttttctg atatagttgg cagaattgta gtttatcctt atgaaattaa
    21241 tattggttta acaataggtg tatttggaac aatcattttc cttatcttac ttatgaaagg
    21301 taggaaaaat tatgcgcaac aataataaaa aaataatgct tttaattgta gtcacgttct
    21361 taattagtat gctgtactta tttgttggta ttgattttga aatatttgaa tatcaatttt
    21421 caagtcgttt aagaaagttc atattaatta ttttagtagg tgctgccatt gcaacatccg
    21481 ttgttatttt ccaagcgatt acaaataatc gtttattgac accatcaata atgggattag
    21541 atgcagttta tttatttatc aaagtattgc cagtcttttt atttggaatt caatcggtgt
    21601 gggttactaa tgtatatttg aattttatat taacacttat aacgatggtg ttattcgcac
    21661 taatcctatt ccaaggtatc tttaaaattg gacatttttc aatttatttt atcttactta
    21721 ttggtgtcct tttaggaaca ttttttagaa gcattacagg ttttattcaa ttgattatgg
    21781 atcctgaatc atttttagca atacaaagta gtatgtttgc taattttaat gcctctaatt
    21841 cgaatttagt ttctttttca gcagtattat tagtaatctt attagtcatt acaatttttc
    21901 tattgccgta tttagatgta ttgcttttag gtcgtgctga agcaattaat cttggtatat
    21961 cgtatgaaaa attaacgcgg attctacttg taatagtttc tgtcttagtt tctgtgtcaa
    22021 ctgcattagt aggaccaatt acatttttag gcttattgac tgtaaatcta gcgcatgaac
    22081 taatgaagac gtatgaacat aaatatatat taatcgcgac aatttgcttg agttggatta
    22141 gtttatttag tgcgcaatgg gtagttgaaa atgtgtttga ggctacgaca gaaatgagta
    22201 tacttattga tttaattggt ggaagttatt tcatttatct attagttaga aggagaaatg
    22261 cgcaatgatt caagttggaa atttaactaa aactataaat aatcaaatga tattggacga
    22321 tattagcata gaaattgaaa aaggtaagtt gacttcttta attggaccta atggagcagg
    22381 gaagagtacg ttactttcag cgatatgtcg cttaattcgg tttgatgaag gggaagtaaa
    22441 aatagatgga cagcttatgt ctgattataa aaacaatgat ttgtcgaaaa agatatcgat
    22501 tttaaagcaa acgaaccata cagaaatgaa cattactgta gaacaattag ttaatttcgg
    22561 acgattccct tattctaaag gacgtttaac gaaagaagat catgaaattg ttaatgatgc
    22621 tttagatttg ttgcaattac aagatattag aaagcgtaat ataaaatcat tgtctggtgg
    22681 acaacgtcaa cgtgcctata tagcgatgac cattgcacaa gatactgaat atattctttt
    22741 agatgaaccg ttaaataatt tagatatgaa gcatgctgtt caaattatgc aaacgttaaa
    22801 aatgttagca cataaaatga ataaagcgat tgtcattgtg ttacatgata ttaactttgc
    22861 gtcctgttat tcagatcaaa ttgtagcact gaaaaacgga caactagtta aatcagattt
    22921 gaaagataat gtcattcaaa gtagtgtttt aagtgattta tatgacatgg atattcaaat
    22981 tgaacatata aaaaatcaaa ggatttgttt atattttaag gattgataat tcggaaacac
    23041 tttaaagggg tgatgcacca attaaagaaa gtttaactat aaatcattta tttatttttc
    23101 acatcaagca cacagattaa gccaaaagag gagaaaatta tattatgaag aaaacagtct
    23161 tatatttagt agtagcagta atgtttttat tagcagcatg tggtaacaat tctgataaag
    23221 aacaatcaaa atcagaaact aaaggttcta aagatacagt gaaaattgaa aacaactata
    23281 aaatgcgtgg cgagaaaaaa gatggtagcg atgctaaaaa agttaaagaa actgttgaag
    23341 taccaaaaaa tcctaaaaat gcagttgtat tagattatgg tgcattagat gtaatgaaag
    23401 aaatgggctt atcagacaaa gtaaaagcat tacctaaagg ggaaggcggc aagtcattac
    23461 cgaacttctt agagtcattt aaagatgaca agtatacaaa tgttggtaac ttgaaagaag
    23521 ttaatttcga taaaattgca gcaacaaaac cagaagtaat ctttatctca ggccgtacag
    23581 ctaatcaaaa gaatttagat gaattcaaaa aagctgcacc aaaagcaaaa attgtttatg
    23641 ttggtgcaga tgaaaagaac ttaattggtt caatgaaaca aaacactgaa aatatcggta
    23701 aaatttacga caaagaagat aaagctaaag aattaaataa agatttagat aacaaaattg
    23761 cttcaatgaa agataaaact aagaagttca acaaatcagt tatgtattta ttagttaatg
    23821 aaggtgaatt atctacttat ggacctaaag gtcgtttcgg tggattagtt tacgatacat
    23881 taggtttcaa cgcggttgat aaaaaagtaa gcaatagtaa ccacggacaa aatgtctcta
    23941 acgaatacat taataaagaa aatccagatg ttattttagc aatggataga ggacaggctg
    24001 taagtggtaa atcaactgcg aaacaagcat taaataatcc tgtattaaaa aatgttaaag
    24061 caattaaaga agacaaagtt tataatttag atcctaaatt atggtacttt gcagctggat
    24121 caactacaac tacaattaaa caaattgagg aacttgaaaa agttgtaaaa taattttaaa
    24181 agtggggaac aatggttaaa ggtcttaatc attgttcccc acttttcttt taaaaaagga
    24241 atctgggacg ttaatcaatg tcctagactc taaaatgttc tgttgtttgt cgttggttga
    24301 atgaacatgt acttgtaaca agttcatttc aataccagtg ggctcccaac atagagaaat
    24361 ttgatttcca atttctactg acaatgcaag ttggcggggc ccaaacatag agaatatcaa
    24421 aaaggaattc tatagaagtg gtgctttatc atgtctgtcc cactccctat aatgttttgg
    24481 ctatgttgtt taaatttcga aataaatatg ataatgatat ttgcagcgat tgttaaatcg
    24541 agattgacaa tttggacaac gttcaaccat catatattca ttgattgtta attcgtgttt
    24601 gcatacaccg cataagattg ctttttcgtt aaatgaaggc tcagaccaac gcttaatggc
    24661 gtgcttttca aactcattat ggcacttata gcatggatag tatttattac aacatttaaa
    24721 tttaatagca ataatatctt cttcggtaaa ataatggcga cagcgtgttt cagtatcgat
    24781 taatgaacca taaactatag gcatagacaa agctccttaa cttacgattc ctttggatgt
    24841 tcaccaataa tgcgaacttc acgatttaat tcaatgccaa atttttcttt gacggtcttt
    24901 tgtacataat gaataaggtt ttcgtaatct gtagcagttc cattgtctac atttaccata
    24961 aaaccagcgt gtttagttga aacttcaacg cctccaatac ggtgaccttg caaattagaa
    25021 tcttgtatca atttacctgc aaaatgacca ggcggtcttt ggaatacact accacatgaa
    25081 ggatactcta aaggttgttt agattctcta cgttctgtta aatcatccat tttagcttgt
    25141 atttcagtca ttttaccagg agctaaagta aatgcagctt ctaatacaac taagtgttct
    25201 ttttgaataa tgctattacg ataatctaac tctaattctt ttgttgtaag tttaattaat
    25261 gagccttgtt cgtttacgca aagcgcatag tctatacaat ctttaacttc gccaccataa
    25321 gcgccagcat tcatatacac agcaccacca attgaacctg gaataccaca tgcaaattca
    25381 aggccagtaa gtgcgtaatc acgagcaaca cgtgagacat caataattgc agcgccgcta
    25441 ccggctatta tcgcatcatc agatacttcg atatgatcta gtgataataa actaattaca
    25501 atgccacgaa taccaccttc acggataata atatttgagc cattgcctaa atatgtaaca
    25561 ggaatctcat tttgataggc atatttaaca actgcttgta cttcttcatt tttagtaggg
    25621 gtaatataaa agtcggcatt accacctgtc ttagtataag tgtatcgttt taaaggttcg
    25681 tcaactttaa ttttttcatt tgggataagt tgttgtaaag cttgatagat gtctttattt
    25741 atcacttctc agtacatcct tt
//
LOCUS       DAPSKH010000040        25622 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPSKH010000040 DAPSKH010000000
VERSION     DAPSKH010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 25622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25622
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.040"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(57..272)
                     /locus_tag="RPH49_001730"
     CDS             complement(57..272)
                     /locus_tag="RPH49_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124872.1"
                     /translation="MSINIDPEKFAELVVMSNPSKFEDAEDIAKESLKLYINAYRLAE
                     RYSTIATNCYDTAEVIKELKKTDLQLK"
     gene            446..1243
                     /locus_tag="RPH49_001731"
     CDS             446..1243
                     /locus_tag="RPH49_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDY5124873.1"
                     /translation="MRIMFIGDIVGKIGRDAIETYIPQLKQKYKPTVTIVNAENAAHG
                     KGLTEKIYKQLLRNGVDFMTMGNHTYGQREIYDFIDEAKRLVRPANFPDEAPGIGMRF
                     IQINDIKLAVINLQGRAFMPDIDDPFKKADQLVKEAQEQTPFIFVDFHAETTSEKYAM
                     GWHLDGRASAVVGTHTHIQTADERILPKGTGYITDVGMTGFYDGILGINKTEVIERFI
                     TSLPQRHVVPNEGRSVLSGVVIDLDKEGKTKHIERILINDDHPFSTF"
     gene            1383..3143
                     /locus_tag="RPH49_001732"
     CDS             1383..3143
                     /locus_tag="RPH49_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:acceptor oxidoreductase subunit alpha"
                     /protein_id="HDY5124874.1"
                     /translation="MKPQLSWKVGGQQGEGIESTGEIFATAMNRKGYYLYGYRHFSSR
                     IKGGHTNNKIRVSTTPVHAISDDLDILIAFDQETIDVNHHEMREDSIILADAKAKPVK
                     PEGCHAQLIELPFTATAKELGTALMKNMVAIGATSALMNLNTNTFEELITNMFSKKGD
                     KVVEVNIQALNEGYQLMQSRLPEIYGDFELESTDALPHLYMIGNDAIGLGAIAAGSQF
                     MAAYPITPASEVMEYMIANISKVNGAVIQTEDEIAAVTMAIGANYGGVRAFTASAGPG
                     LSLMMEAIGLSGMTETPLVIINTQRGGPSTGLPTKQEQSDLMQMIYGTHGDIPKIVVA
                     PTDAEDAFYLTMEAFNLAEQYQCPVIVLSDLQLSLGKQTVEKLDYNRIEIKRGEIIQS
                     DIEREEDDKGYFKRYALTSNGVSPRPIPGIKGGIHHITGVEHNEEGKPSESASNRQQQ
                     MEKRMRKIEQLLIELPVEANLQHEDADILYIGFISTKGAIQEGSNRLNQQGIKVNTIQ
                     IRQLHPFPTSVIQDAVNKAKKVVVVEHNYQGQLSSIIKMNVNIHDKIENYTKYDGTPF
                     LPHEIEEKGKIIATEIKEMV"
     gene            3144..4010
                     /locus_tag="RPH49_001733"
     CDS             3144..4010
                     /locus_tag="RPH49_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoacid:ferredoxin oxidoreductase subunit
                     beta"
                     /protein_id="HDY5124875.1"
                     /translation="MATFKDFRNNVKPNWCPGCGDFSVQAAIQKAAANIGLEPEEVAI
                     ITGIGCSGRLSGYINSYGVHSIHGRALPLAQGVKMANKDLTVIASGGDGDGYAIGMGH
                     TIHALRRNMNMTYIVMDNQIYGLTKGQTSPSSAVGFVTKTTPKGNIEKNVAPLELALS
                     SGATFVAQGFSSDIKGLTKLIEDAINHDGFSFVNVFSPCVTYNKINTYDWFKEHLTSV
                     DDIENYDSTDKQLATKTVIEHESLVTGIVYQDKETPSYESQIKELDDTPLAKRDIKIT
                     EDTFNALTEQFI"
     gene            4104..4397
                     /locus_tag="RPH49_001734"
     CDS             4104..4397
                     /locus_tag="RPH49_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HDY5124876.1"
                     /translation="MKDTLMSIQIIPKTPNNDNVIPYVDEAIKIIDESGLHFRVGPLE
                     TTVQGNMNECLILIQSLNERMVELECPSIISQVKFYHVPDGITIETLTEKYDE"
     gene            4531..6075
                     /gene="miaB"
                     /locus_tag="RPH49_001735"
     CDS             4531..6075
                     /gene="miaB"
                     /locus_tag="RPH49_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDY5124877.1"
                     /translation="MNEEQRKASSVDVLAERDKKAEKDYSKYFEHVYQPPNLKEAKKR
                     GKQEVRYNRDFQIDEKYRGMGNERTFLIKTYGCQMNAHDTEVIAGILEALGYQATTDI
                     NTADVILINTCAIRENAENKVFSEIGNLKHLKKERPDILIGVCGCMSQEESVVNKILK
                     SYQNVDMIFGTHNIHHLPEILEEAYLSKAMVVEVWSKEGDVIENLPKVREGNIKAWVN
                     IMYGCDKFCTYCIVPFTRGKERSRRPEDIIDEVRELAREGYKEITLLGQNVNSYGKDL
                     QDIEYDLGDLLQAISKIAIPRVRFTTSHPWDFTDHMIDVISEGGNIVPHIHLPVQSGN
                     NAVLKIMGRKYTRESYLDLVKRIKDRIPNVALTTDIIVGYPNESEEQFEETLTLYDEV
                     GFEHAYTYLYSQRDGTPAAKMKDNVPLDVKKERLQRLNKKVGHYSQIAMSKYEGQTVT
                     VLCEGSSKKDDQVLAGYTDKNKLVNFKAPKEMIGKLVEVRIDEAKQYSLNGSFVKEVE
                     PEMVIQ"
     gene            6076..6441
                     /locus_tag="RPH49_001736"
     CDS             6076..6441
                     /locus_tag="RPH49_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RicAFT regulatory complex protein RicA family
                     protein"
                     /protein_id="HDY5124878.1"
                     /translation="MYNKDDVLKQADNIANKIKNLDTIKTYQQIEAQIHQNQTIKTKM
                     DMLKKHQKQAVNFQNYGKQNALEQSEHTIQSIEAEINTLPIVEQFQTSQYEANQLLKM
                     FVSTMETRLNDHNKAKHSD"
     gene            6468..6959
                     /gene="thiW"
                     /locus_tag="RPH49_001737"
     CDS             6468..6959
                     /gene="thiW"
                     /locus_tag="RPH49_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HDY5124879.1"
                     /translation="MKSRKLAITALLIAINVVLSSIIIIPLGPVKAAPVQHFVNVLSA
                     VIVGPWYGLAQALISSILRVLFGTGTAFAFPGSMIGVLLASMFYIYRKHIFMAAVGEV
                     LGTGVIGSLICIPLAYFLGLQDFFIKPLMITFIVSSAIGSIISYFLLITLKKRGILQR
                     FIK"
     gene            7262..9880
                     /gene="mutS"
                     /locus_tag="RPH49_001738"
     CDS             7262..9880
                     /gene="mutS"
                     /locus_tag="RPH49_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDY5124880.1"
                     /translation="MSNVTPMMQQYLKIKSEYQDCLLFFRLGDFYEMFYEDAKEASRV
                     LEITLTKRDAKKENPIPMCGVPYHSADSYIDTLVNNGYKVAICEQMEDPKQTKGMVRR
                     EVVRIVTPGTVMEQGGVDDKQNNYILSFVMNQPEIALSYCDVSTGELKVTHFNDEATL
                     LNEITTINPNEVVINDNISDNLKRQINMVTETITVRETLSSEIYSVNQTEHKLMYQAT
                     QLLLDYIHHTQKRDLSHIEDVVQYAAIDYMKMDFYAKRNLELTESIRLKSKKGTLLWL
                     MDETKTPMGARRLKQWIDRPLISKEQIEARLDIVDEFSAHFIERDTLRTYLNQVYDIE
                     RLVGRVSYGNVNARDLIQLKHSISEIPNIKALLNSMNQNTLVQVNQLEPLDDLLDILE
                     QSLVEEPPISVKDGGLFKVGFNTQLDEYLEASKNGKTWLAELQAKERQRTGIKSLKIS
                     FNKVFGYFIEITRANLQNFEPSEFGYMRKQTLSNAERFITDELKEKEDIILGAEDKAI
                     ELEYQLFVQLREEVKKYTERLQQQAKIISELDCLQSFAEIAQKYNYTRPSFSENKTLE
                     LVESRHPVVERVMDYNDYVPNNCRLDNETFIYLITGPNMSGKSTYMRQVAIISIMAQM
                     GAYVPCKEAVLPIFDQIFTRIGAADDLVSGKSTFMVEMLEAQKALTYATEDSLIIFDE
                     IGRGTSTYDGLALAQAMIEYVAETSHAKTLFSTHYHELTTLDQALPSLKNVHVAANEY
                     KGELIFLHKVKDGAVDDSYGIQVAKLADLPEKVISRAQVILSEFEASAGKKSSISNLK
                     MVENEPEINQENLNLSVEETTDTLSQKDFEQASFDLFENDQESEIELQIKNLNLSNMT
                     PIEALVKLSELQNQLK"
     gene            9893..11902
                     /gene="mutL"
                     /locus_tag="RPH49_001739"
     CDS             9893..11902
                     /gene="mutL"
                     /locus_tag="RPH49_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDY5124881.1"
                     /translation="MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEIS
                     IEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSKLDQDEDLFHIRTLGFRGEALAS
                     ISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
                     KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVAR
                     DLVHISGDTSDYHIEGFVAKPEHSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLT
                     IGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSKIQEAFKDRILIPKN
                     NLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNSKPFMEENQNDEIVIK
                     EDSYNPFVTKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNDDTTVQ
                     NYENKASDDYYDVNDIKGTKSKDPKRRIPYMEIVGQVHGTYIIAQNEFGMYMIDQHAA
                     QERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIMLEHFGG
                     HDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHY
                     LQKHEMSDLIDQLREAEDPFTCPHGRPIIINFSKYELEKLFKRVM"
     gene            11908..12450
                     /locus_tag="RPH49_001740"
     CDS             11908..12450
                     /locus_tag="RPH49_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HDY5124882.1"
                     /translation="MNQVNNNILPAIRNIKDLEKLIKTDYKMCVLLDMHIGHIKSIME
                     LLKQNHIECFIHIDLIKGLSHDEFASEFIIQQYKPKGIVSTKSKVIKKAKSLNTLTIF
                     RVFIIDSQALKRSIDLIKKVEPDFVEVLPGVASKAIHHIQKETNTQVIAGGLINTIDE
                     VNEAVKNGAKYVTTSYDKLW"
     gene            12915..13733
                     /locus_tag="RPH49_001741"
     CDS             12915..13733
                     /locus_tag="RPH49_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDY5124883.1"
                     /translation="MNVYLAEFLGTAILILFGGGVCANVNLKRSAANGADWIVITAGW
                     GLAVTMGVFAVGQFSGAHLNPAVSLALALDGSFDWSLVPGYIVAQMLGAIVGATIVWL
                     MYLPHWKATEEAGAKLGVFSTAPAIKNYFANFLSEIIGTMALTLGILFIGVNKIADGL
                     NPLIVGALIVAIGLSLGGATGYAINPARDLGPRIAHAILPIAGKGGSNWSYAIVPILG
                     PIAGGLLGAVVYAVFYKHTFNIGCAIAIVVVIITLILGYILNKSSKKGDIESIY"
     gene            13862..15358
                     /gene="glpK"
                     /locus_tag="RPH49_001742"
     CDS             13862..15358
                     /gene="glpK"
                     /locus_tag="RPH49_001742"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDY5124884.1"
                     /translation="MEKYILSIDQGTTSSRAILFNQKGEIAGVAQREFKQYFPQSGWV
                     EHDANEIWTSVLAVMTEVINENDVRADQIAGIGITNQRETTVVWDKHTGRPIYHAIVW
                     QSRQTQSICSELKQQGYEQTFRDKTGLLLDPYFAGTKVKWILDNVEGAREKAENGDLL
                     FGTIDTWLVWKLSGKAAHITDYSNASRTLMFNIHDLEWDDELLELLTVPKNMLPEVKA
                     SSEVYGKTIDYHFYGQEVPIAGVAGDQQAALFGQACFERGDVKNTYGTGGFMLMNTGD
                     KAVKSESGLLTTIAYGIDGKVNYALEGSIFVSGSAIQWLRDGLRMINSAPQSESYATR
                     VDSTEGVYVVPAFVGLGTPYWDSEARGAIFGLTRGTEKEHFIRATLESLCYQTRDVME
                     AMSKDSGIDVQSLRVDGGAVKNNFIMQFQADIVNTSVERPEIQETTALGAAFLAGLAV
                     GFWESKDDIAKNWKLEEKFDPKMDEGEREKLYRGWKKAVEATQVFKTE"
     gene            15516..17189
                     /locus_tag="RPH49_001743"
     CDS             15516..17189
                     /locus_tag="RPH49_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase/oxidase"
                     /protein_id="HDY5124885.1"
                     /translation="MALSTFKREHIKKNLRNDEYDLVIIGGGITGAGIALDASERGMK
                     VALVEMQDFAQGTSSRSTKLVHGGLRYLKQFQIGVVAETGKERAIVYENGPHVTTPEW
                     MLLPMHKGGTFGKFSTSIGLGMYDRLAGVKKSERKKMLSKKETLAKEPLVKKEGLKGG
                     GYYVEYRTDDARLTIEVMKRAAEKGAEIINYTKSEHFTYDKNQQVNGVKVIDKLTNEN
                     YTIKAKKVVNAAGPWVDDVRSGDYARNNKKLRLTKGVHVVIDQSKFPLGQAVYFDTEK
                     DGRMIFAIPREGKAYVGTTDTFYDNIKSSPLTTQEDRDYLIDAINYMFPSVNVTDEDI
                     ESTWAGIRPLIYEEGKDPSEISRKDEIWEGKSGLLTIAGGKLTGYRHMAQDIVDLVSK
                     RLKKDYGLTFSPCNTKGLAISGGDVGGSKNFDAFVEQKVDVAKGFGIDEDVARRLASK
                     YGSNVDELFNIAQTSQYHDSKLPLEIYVELVYSIQQEMVYKPNDFLVRRSGKMYFNIK
                     DVLDYKDSIIDIMADMLDYSPAQIEAYTEEVEQAIKEAQHGNNQPAVKE"
     gene            17339..18253
                     /locus_tag="RPH49_001744"
     CDS             17339..18253
                     /locus_tag="RPH49_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5124886.1"
                     /translation="MTEKQFKLTVQDNTNIEVKVNFTDVDSKGIIHIFHGMAEHMERY
                     DKLAHALSKDGFDVICHNHRGHGINIDESTRGHYDDMKRVIGDAFEVAQTVRGNVDKP
                     YIIIGHSMGSVIARLFVETYPQYVDGLILSGTGMYPLWKGLPTVKVLQLITKIYGAEK
                     RVEWVNQLVSNSFNKKIRPLRTQSDWISSNPTEVDNFIKDPYSGFNVSNQLLYQTAYY
                     MLHTSQLKNIKMLNHAMPILLVSGCDDPLGDYGKGILKLANIYRKAGIKNVKVNLYHH
                     KRHEVLFEKDHDKIWEDLFKWLNQFYKK"
     gene            18271..19206
                     /gene="miaA"
                     /locus_tag="RPH49_001745"
     CDS             18271..19206
                     /gene="miaA"
                     /locus_tag="RPH49_001745"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDY5124887.1"
                     /translation="MNKNKPFIVVIVGPTASGKTELSIELAKRINGEIISGDSMQVYK
                     HMNIGTAKVTPEEMDGIPHHLIDILNPDDTFSAYEFKRLAEDLITDITNRGKVPIIAG
                     GTGLYIQSLIYNYELEDETVTPAQLSIVKQKLSALEHLDNQQLHDYLDQFDAVSAENI
                     HPNNRQRVLRAIEYYLKTKKLLSNRKKVQQFTENYDTLLLGIEMSRKTLYSRINKRVD
                     IMLDHGLFREVQQLVEQGYESCQSMQAIGYKELIPVINGQMIYEDAVNDLKQHSRQYA
                     KRQMTWFKNKMSVHWLDKENMSLQMMLDEITTQIK"
     gene            19221..19454
                     /gene="hfq"
                     /locus_tag="RPH49_001746"
     CDS             19221..19454
                     /gene="hfq"
                     /locus_tag="RPH49_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDY5124888.1"
                     /translation="MIANENIQDKALENFKANQTEVTVFFLNGFQMKGVIEEYDKYVV
                     SLNSQGKQHLIYKHAISTYTVETEGQASTESEE"
     gene            complement(19676..20152)
                     /locus_tag="RPH49_001747"
     CDS             complement(19676..20152)
                     /locus_tag="RPH49_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDY5124889.1"
                     /translation="METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEG
                     LQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEH
                     QLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL"
     gene            20264..21502
                     /gene="hflX"
                     /locus_tag="RPH49_001748"
     CDS             20264..21502
                     /gene="hflX"
                     /locus_tag="RPH49_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDY5124890.1"
                     /translation="MAQQQIHDTKNKLEKAVLVGVHAQDDKQFNFESTMEELSSLSET
                     CQLEVLGQITQNRDRVDRKYYVGKGKIEEIQAFIEFKDIDVVITNDELTTAQSKSLNE
                     ALGVKIIDRTQLILEIFALRARSKEGKLQVELAQLDYLLPRLQGHGKSLSRLGGGIGT
                     RGPGETKLEMDRRHIRTRMNEIKHQLRTVEEHRERYRNKRNQNQVFQVALVGYTNAGK
                     SSWFNVLANEETYEKDQLFATLDPKTRQIQINDGFNLIISDTVGFIQKLPTTLIAAFK
                     STLEEAKGADLLVHVVDSSHPEYRTQYDTVNDLIKQLDMSHISQIVIFNKKDLCDHAS
                     NRPASDLPNVFVSSKNDGDKLLVKTLFIDEIKRQLTYYDEAIATNNADRLYFLKQHTL
                     VTELKYDEIENVYRIKGFKK"
     gene            21521..22759
                     /locus_tag="RPH49_001749"
     CDS             21521..22759
                     /locus_tag="RPH49_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDY5124891.1"
                     /translation="MKDISKIVADVESTLAPYFKEIEETAYINQEKVLNAFHHVKATE
                     SDLQGSTGYGYDDFGRDHLEEIYAQAFKAEDAIVRPQIISGTHAITIALQSLLKHGDE
                     LIYITGSPYDTLLEVIGVNGNGIESLMEYGVSYKDIALKEGKIDIESVLDGVSERTKV
                     IAIQRSKGYDQRPSIPLDEIEQVIIRLKEVHPNILIFVDNCYGEFVERREPIECGADL
                     IAGSLIKNPGGGLAKIGGYIAGRKDLIERCGYRLTAPGIGKEAGASLNALLEMYQGFF
                     LAPHVVSQSLKGALFTSLFLEKMNMNTTPKYYEKRTDLIQTVKFKTKEQMISFCQSIQ
                     HASPINAHFSPEPSYMPGYEDDVIMAAGTFIQGSSIELSADGPIRPPYEAYVQGGLTY
                     EHVKIAVTRAVNQLKEQGLI"
     gene            23003..23371
                     /locus_tag="RPH49_001750"
     CDS             23003..23371
                     /locus_tag="RPH49_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDY5124892.1"
                     /translation="MISNDAIRRNMAVFSMSVVSKLTDLTPRQIRYYETHELIKPERT
                     EGQKRLFSLNDLERLLEIKSLLEKGFNIKGIKQIIYDSQEHLTTDEQEIRKKMIVDAT
                     QKPIGETLPINRGDLSRFIK"
     gene            23390..24730
                     /gene="glnA"
                     /locus_tag="RPH49_001751"
     CDS             23390..24730
                     /gene="glnA"
                     /locus_tag="RPH49_001751"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDY5124893.1"
                     /translation="MPKRTFTKDDIRKFAEEENVRYLRLQFTDILGTIKNVEVPVSQL
                     EKVLDNEMMFDGSSIEGFVRIEESDMYLHPDLDTWVIFPWTAGQGKVARLICDVYKTD
                     GTPFEGDPRANLKRVLKEMEDLGFTDFNLGPEPEFFLFKLDEKGEPTLELNDDGGYFD
                     LAPTDLGENCRRDIVLELEDMGFDIEASHHEVAPGQHEIDFKYADAVTACDNIQTFKL
                     VVKTIARKHNLHATFMPKPLFGVNGSGMHFNVSLFKGKENAFFDPNTEMGLTETAYQF
                     TAGVLKNARGFTAVCNPLVNSYKRLVPGYEAPCYIAWSGKNRSPLIRVPSSRGLSTRI
                     EVRSVDPAANPYMALAAILEAGLDGIKNKLKVPEPVNQNIYEMNREEREAVGIQDLPS
                     TLYTALKAMRENEVIKKALGNHIYNQFINSKSIEWDYYRTQVSEWERDQYMKQY"
     gene            25223..25420
                     /locus_tag="RPH49_001752"
     CDS             25223..25420
                     /locus_tag="RPH49_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124894.1"
                     /translation="MNCYDEIFNTIKELIENKEISSYQINKDTGISYGNINAMRRRER
                     RIENLSLKNAKILYEYAKKVL"
BASE COUNT         9466 a         3491 c         4848 g         7817 t
ORIGIN      
        1 tagggattta tgtcccagcc tctgtaatat taattaggat ttatttctaa gttgagttat
       61 tttaattgta aatctgtttt ctttaattct tttataactt ctgcagtatc ataacaattt
      121 gttgcaattg ttgaatatct ctctgctaaa cgatatgcat taatgtaaag ctttaaactt
      181 tctttagcta tatcctctgc atcttcgaat tttgatgggt tagacataac cactaattct
      241 gcaaattttt ctggatcaat attaatagac atgtatttat ttacaactcc tatttatttt
      301 gatgtcttaa tactaacata ttgaagtttt cagacaaagt aatgtctctt tataattgaa
      361 gaaaaataat tcaaagaatt taatatttac tttaaatatt agaacgtatg aattaaacta
      421 gtatttatga gaggatgaac aaaacatgag aataatgttt ataggggata tcgtaggtaa
      481 aattggacga gacgcaattg aaacgtacat acctcaactg aagcaaaagt ataaaccaac
      541 agttacaatt gtaaatgctg aaaatgcagc acatggtaaa ggtttgactg aaaaaatata
      601 taaacaatta ctaagaaatg gtgtagattt catgactatg ggtaatcaca catatggtca
      661 acgtgaaatt tatgatttta tagatgaagc aaaacgacta gtaagaccag cgaattttcc
      721 ggatgaagcg ccgggaattg gtatgagatt tatacaaatt aatgatatta aacttgcagt
      781 tattaatctg caaggaagag cgtttatgcc agatattgat gatcctttta aaaaggcaga
      841 tcaattagtc aaggaagcac aagaacaaac tccgtttata tttgttgatt ttcatgcaga
      901 aacaacttct gaaaagtatg caatgggatg gcatttagat ggtagagcta gcgctgttgt
      961 tggaacgcat acacacattc aaacagcaga tgaacgtatt ttaccaaagg ggacagggta
     1021 tataacggat gttggtatga caggttttta tgacggcatt ttaggaataa ataaaacaga
     1081 ggtaattgag cgttttatca ctagtttgcc acaaagacat gttgttccaa atgaaggtag
     1141 aagtgtatta tctggtgttg ttattgattt agacaaagaa ggtaaaacga agcacatcga
     1201 acgtatattg ataaatgatg accatccatt ttcaacattt taaaattacg taagtaaaca
     1261 ttcgaattgg accctatcgt ccattagtat gaatttaata tagtaccact gtttacatag
     1321 taaatcggtg gttctttttg ttatcattta atatgaaata tatccatagg aggcatataa
     1381 ctatgaaacc acaattatcg tggaaagttg gcggtcaaca aggcgaaggt attgaatcaa
     1441 ctggggaaat cttcgctacg gctatgaata gaaaaggata ttatttatat ggatatagac
     1501 atttttcaag tcgtatcaaa ggtggacata cgaataataa aattagagtt tctacgacgc
     1561 ctgttcatgc aattagtgat gatttagata ttttgattgc atttgaccaa gaaacaattg
     1621 atgttaacca tcatgaaatg agagaagaca gtattatttt agctgatgcc aaggctaaac
     1681 ctgtgaaacc agaaggatgt catgcacagc ttattgaatt accttttaca gcaaccgcta
     1741 aagaattagg tacagcatta atgaaaaaca tggttgcaat aggtgctact agcgcattga
     1801 tgaatttgaa tacaaataca tttgaagaac ttattactaa tatgttttct aaaaaaggtg
     1861 acaaggtagt tgaagtcaat atccaagcat taaacgaagg ttatcaatta atgcaatctc
     1921 gcttacctga aatctacggg gactttgaat tagagtcaac agatgcacta ccacatctat
     1981 atatgattgg taacgatgcc attggattag gtgcaattgc tgcaggttcg caatttatgg
     2041 cggcatatcc tattacacct gcgtctgaag ttatggaata tatgattgcc aatatatcta
     2101 aagtaaacgg agcggttatt caaacagaag atgaaattgc tgctgtaact atggctattg
     2161 gtgcaaatta tggtggagtc agagcgttta cggctagtgc tggtccaggt ttatctttaa
     2221 tgatggaagc aattggatta tctggtatga ctgaaacgcc attagtcatt attaataccc
     2281 aacgaggtgg accttctact ggattaccta cgaaacaaga acagtcagat ttaatgcaaa
     2341 tgatttatgg tacacatggt gatattccaa aaattgttgt agcaccaact gatgcagaag
     2401 atgcatttta tttaactatg gaagccttta atttagcaga acaatatcaa tgccctgtta
     2461 tagttctaag tgatttgcaa ttatctttag gtaaacaaac tgttgaaaaa ttagattata
     2521 atcgcattga aattaaacgt ggtgaaatca ttcaatctga tattgaacgt gaagaagatg
     2581 ataaaggtta tttcaagcgt tatgcgttaa catccaatgg tgtttctcct agacctatcc
     2641 ccggtattaa aggaggtatt catcatataa ctggtgtgga acacaatgaa gaaggtaaac
     2701 ctagtgaatc tgcatcaaat agacaacaac aaatggaaaa acgaatgcgt aaaattgagc
     2761 agttactaat tgaattgcca gtagaagcta acttacaaca tgaagatgca gatattcttt
     2821 atatcggttt tatttctaca aaaggtgcaa ttcaagaagg tagtaaccgt ttgaatcaac
     2881 aaggcataaa agttaacact atacaaatta gacaattgca tccattccca acaagcgtta
     2941 ttcaagatgc agttaataaa gcgaagaaag tcgttgtagt ggagcacaat tatcaaggac
     3001 aattgtctag tattataaaa atgaatgtca atattcatga taagattgaa aattatacaa
     3061 agtatgatgg gacacctttc ctaccacatg aaatcgaaga aaaaggcaaa ataattgcta
     3121 ctgaaataaa ggagatggta tagatggcga catttaaaga ttttagaaat aatgttaagc
     3181 ctaactggtg ccctggatgt ggcgatttct cagtacaagc tgcaattcaa aaagcagccg
     3241 caaatatagg gttagaacct gaagaagtag ctatcatcac cggtatagga tgttctggcc
     3301 gtctttcagg atatattaat tcttatggcg ttcattctat tcacggacgt gcattacctt
     3361 tagctcaagg tgtaaaaatg gcgaataaag atttaactgt tattgcatct ggaggagatg
     3421 gtgatggtta tgctataggt atggggcata caatccatgc tttaagaaga aatatgaaca
     3481 tgacgtatat agtcatggat aatcaaattt atggtttgac aaagggacaa acatcgccgt
     3541 catcagcagt aggatttgtt actaaaacaa cgccaaaagg taatatagaa aaaaatgttg
     3601 cgcctttaga attagcatta tcatctggtg ccacatttgt agcccaaggt ttttcaagcg
     3661 atattaaagg attaacaaaa ctaattgaag atgcaattaa tcatgatgga ttttcattcg
     3721 ttaatgtctt ttcaccttgt gtgacttata ataaaattaa cacatacgat tggtttaaag
     3781 aacatttaac aagtgttgat gacattgaaa attatgattc tacagataaa caattagcga
     3841 ctaaaactgt tattgaacat gaatctttag taactggtat tgtttatcaa gataaagaaa
     3901 caccatcata tgaatctcaa attaaagagt tagatgatac accacttgct aaaagagata
     3961 tcaaaattac tgaagacacc ttcaatgcat taactgaaca atttatttaa taattaaaac
     4021 tgagtcgtat aaatgtattt ataacagatc catttatgct actcagtttt ttactattac
     4081 aaaaaataaa ggagttttta aaaatgaaag acacattaat gagtatacaa ataattccta
     4141 aaacaccaaa caatgacaat gttattcctt acgtagacga ggcgattaaa ataattgacg
     4201 aatctggttt gcattttaga gtaggtccgt tagaaacgac agtacaagga aatatgaatg
     4261 aatgtttaat tttaatacaa tcattaaatg aacgaatggt ggaacttgaa tgtccaagta
     4321 ttattagcca agttaagttt tatcatgtgc cagatggcat cactattgaa actttaactg
     4381 aaaaatatga tgaataacat taaaagtgaa gtaaactgga tttgaattgg cttgttagag
     4441 atgacgtata actttaactg tttttgcact ttatagttaa atttaatata attattaaat
     4501 gatacgggca aatagaaagg attttgtaaa gtgaacgaag aacaaagaaa agcaagttct
     4561 gtagatgttt tagctgagag agataagaaa gcagaaaaag attatagtaa atattttgaa
     4621 catgtttatc agccgcctaa tttaaaagaa gcgaaaaaaa gaggtaaaca agaagttcgt
     4681 tataatagag atttccaaat tgatgaaaaa tatcgcggta tggggaacga gcgtacattt
     4741 ttaattaaaa catatggatg tcaaatgaat gcacatgaca ctgaggtcat tgctggtata
     4801 cttgaagcat taggctatca agcaacgact gatattaaca ctgcagatgt tattttaatt
     4861 aatacatgtg cgattagaga aaatgccgag aacaaagtgt ttagtgaaat aggtaatttg
     4921 aagcatttga aaaaagaacg acctgatatt ttaatcggtg tttgtggttg tatgtcacaa
     4981 gaagagtcag tagtgaataa aattttaaaa tcgtatcaaa atgtagatat gatatttggt
     5041 acacataata ttcatcattt accagaaatt ttagaagaag catacttatc taaagcaatg
     5101 gttgttgaag tatggtctaa agaaggagac gttattgaaa atcttccaaa agtccgtgaa
     5161 ggcaacatta aagcatgggt caatattatg tatggttgtg ataagttttg tacatattgt
     5221 attgttccat ttacaagagg taaagaacga agccgcagac ctgaagacat tatagatgaa
     5281 gtacgtgaac ttgctcgtga aggttacaaa gaaataacgc ttttaggtca aaatgtaaat
     5341 tcttatggta aagatttaca ggatatagaa tatgacttag gagatctttt acaagcaatt
     5401 tctaaaatag cgattccaag agttcgtttc acaacaagtc atccttggga ctttacagat
     5461 cacatgattg atgttatttc agagggtggt aatatcgttc cgcatatcca cttgccagtt
     5521 caatctggaa ataatgcagt attaaaaata atgggtagaa aatatacacg agaaagttat
     5581 ttggatttag taaaacgaat caaagataga attcctaatg tagcattaac tacagatatt
     5641 attgtagggt atccaaatga atcagaggaa caatttgaag aaactttaac tctgtatgat
     5701 gaagttggtt ttgaacatgc atatacgtat ttgtattcac aacgtgatgg tacgcctgct
     5761 gctaaaatga aagataatgt acctttagat gtcaaaaagg aacgattgca acgtttgaat
     5821 aaaaaagttg gtcattattc acaaatagct atgagtaagt acgaaggaca aactgtaaca
     5881 gtactttgtg aaggtagtag taaaaaagat gatcaggttc ttgctggcta cactgataaa
     5941 aataagctag ttaatttcaa agcgcctaaa gaaatgattg gtaaactagt ggaagtacga
     6001 atagatgaag ctaaacagta ttcattaaat ggcagttttg taaaggaagt agagccggaa
     6061 atggtgattc aataaatgta taataaagat gacgtgttga aacaagcgga taatattgca
     6121 aataaaatta aaaatttgga tactatcaaa acatatcaac aaattgaagc acagattcat
     6181 cagaaccaaa cgataaagac taaaatggat atgttaaaaa agcatcaaaa acaagcagta
     6241 aactttcaaa attacgggaa acaaaatgcg ctagaacagt cggaacatac cattcaaagt
     6301 atagaagcag aaataaatac attgcccata gttgaacagt ttcaaacttc acaatatgaa
     6361 gcgaatcaat tattgaaaat gtttgtatca acaatggaaa cacgtttaaa tgaccataat
     6421 aaagccaagc atagtgatta attacaaaca aaaaggagaa caatcatatg aaatcaagaa
     6481 aactggctat aactgcactt ttaattgcaa taaatgttgt attaagcagt attatcatca
     6541 ttcctctagg accagttaag gcagcaccag tacagcattt tgtaaatgta ttaagtgcgg
     6601 tcatagtagg tccttggtat ggattagctc aagcgcttat atcatcaatt ttaagagttc
     6661 tttttggtac tggtacagct tttgcatttc caggtagtat gattggagtt ttattggcta
     6721 gtatgtttta catatatcgt aaacatatat tcatggccgc ggtcggtgaa gtacttggaa
     6781 ctggtgtcat cggaagttta atttgtatac cattagcata tttccttggg cttcaagact
     6841 tcttcattaa accgttaatg attacgttca tagtctcaag tgctatcgga tctattataa
     6901 gttatttctt attaattact ctaaaaaaac gtggtattct tcaaaggttt ataaaataat
     6961 tttatgatat atgatttcaa acagagtcat tgttcatttt aatattgaac gcccttactt
     7021 aattaaatgt cttgaatgtt agaattttaa tttaattcta aacatgctat tgacacattt
     7081 tattaggttt gaggcgtttt cttatacatt taagatgctt cgtgattata tggtatgaat
     7141 aggtttgtaa aagtaagtat gttaaaatgt ataagttaaa taattaataa ttagaaagct
     7201 tacaaacgaa tatattgtaa agacaaattt taaaaagaga caagggttgt gaagaaataa
     7261 tatgtctaat gttacaccaa tgatgcagca atatttaaaa ataaaatcag aataccaaga
     7321 ttgcttatta ttttttagac taggtgattt ctatgaaatg ttttatgaag atgccaagga
     7381 ggcatcacgt gtacttgaaa ttactttaac taaaagagat gctaaaaaag aaaatccaat
     7441 tccgatgtgt ggtgttccgt atcattctgc agatagttat atagatacac ttgttaataa
     7501 tggatataaa gtagctattt gtgaacagat ggaagatccg aaacaaacga aaggtatggt
     7561 tagacgtgag gtagtaagaa ttgtgactcc aggaactgtg atggagcaag gtggtgtaga
     7621 tgataaacaa aataactata ttttaagttt tgttatgaat caacctgaaa ttgcgcttag
     7681 ttactgtgat gtttctactg gcgaattaaa ggttacacat tttaatgatg aagcgacttt
     7741 attaaatgaa attacgacga taaaccctaa cgaagttgtt atcaatgaca atatttccga
     7801 taatttaaaa agacaaatta atatggtgac agaaacaata acagtcaggg aaacgttatc
     7861 atcagaaatc tatagtgtga atcaaactga acataaatta atgtatcaag cgacacaatt
     7921 attgctagat tatattcatc atacacaaaa acgtgattta tcgcatatcg aggatgttgt
     7981 tcaatatgca gctatagatt atatgaaaat ggatttttat gctaagagaa accttgagtt
     8041 aacggaaagc attcgattaa aatcaaaaaa aggaacgcta ctttggctaa tggacgaaac
     8101 gaaaacacca atgggagcac gccgcttaaa acaatggata gatagaccac taataagtaa
     8161 agaacaaatt gaagcacgat tagatatcgt tgatgaattt agtgctcatt tcatagaaag
     8221 agacacctta agaacatatc ttaatcaagt gtatgatatt gaacgtcttg ttgggcgtgt
     8281 tagttatgga aatgttaatg cgagagattt aattcaactt aaacattcca tttctgaaat
     8341 accgaatatt aaagcattac taaattctat gaatcagaat actcttgtac aagttaatca
     8401 actagaaccc cttgatgatt tacttgatat attagaacag agtttagtag aagaaccacc
     8461 aatttcagtt aaagatggcg gactattcaa agttggtttt aatacgcaat tagatgaata
     8521 tcttgaagct tcaaaaaacg gaaaaacatg gttagcagaa ttacaagcca aagaaagaca
     8581 acgtacagga ataaaatcat tgaaaataag ctttaataaa gtgtttggtt attttataga
     8641 aataacacgt gccaacttgc aaaattttga accaagtgaa tttggttata tgaggaagca
     8701 aacgttatcg aatgcggaac gttttataac tgatgaactt aaagaaaaag aagatatcat
     8761 tttaggtgcg gaagacaaag ccatcgaatt agaatatcaa ttatttgttc agctacgtga
     8821 agaagttaaa aaatatactg aacgtttaca acaacaagct aaaattattt cagagctaga
     8881 ttgtttacag agctttgcag aaattgctca aaaatataat tacactaggc cttcatttag
     8941 tgaaaataaa acattagaat tagtggaatc taggcaccca gtagtggaaa gagtaatgga
     9001 ttataatgac tatgtgccta ataattgtcg attagataat gaaacattta tatatttaat
     9061 tacaggtccg aatatgtctg gtaaatcgac atatatgaga caagttgcca taattagtat
     9121 aatggcccaa atgggagctt atgtcccttg taaagaggca gtgttaccta tatttgatca
     9181 aatattcact agaataggtg cggcagatga tttggtttca ggtaagagta cgtttatggt
     9241 agaaatgcta gaagcacaaa aggcattaac ttatgcaaca gaggatagtt tgattatttt
     9301 cgatgaaatt ggacgtggta cttcaacgta tgacggttta gctttagcgc aggcaatgat
     9361 agagtatgta gctgaaacat cacatgctaa aacgttattt tcaacacatt atcatgaatt
     9421 gacaacatta gatcaagcat taccaagtct aaaaaatgtt cacgtcgctg ctaatgaata
     9481 taaaggtgaa cttatattct tgcataaagt caaagatggt gcagttgacg atagttatgg
     9541 tattcaagtt gcgaaattag ctgatttacc tgaaaaagtt attagcagag cacaagtgat
     9601 cctaagcgag tttgaagcgt ctgctggtaa aaaatcatcg atatcaaatt taaaaatggt
     9661 cgaaaatgaa cctgaaatta atcaagaaaa tttaaactta agtgttgaag aaacaactga
     9721 tactttatct caaaaagact ttgaacaagc atcatttgat ttgtttgaaa atgatcaaga
     9781 aagcgagatt gaactacaaa ttaaaaattt gaatttatct aatatgacac caattgaggc
     9841 attggtgaag ttaagtgaat tacaaaatca attaaaatag aggtgttgca aaatggggaa
     9901 aattaaagaa ctccaaacct cattagcaaa taaaatcgca gcaggtgaag tagttgaaag
     9961 accgagttct gttgtgaaag aactgttgga aaatgctata gatgcaggcg ctacagaaat
    10021 aagcattgaa gtagaggaat ctggcgtcca atctattcgc gtagtcgata atggaagcgg
    10081 aattgaagcg gaagacttag gattagtatt tcatagacat gcgactagta aattagatca
    10141 agatgaagat ttatttcata ttaggacatt aggattccgt ggtgaagcac tagccagtat
    10201 ttcatcagtt gctaaagtaa cattgaagac ttgcacggat aatgctaatg gaaatgaaat
    10261 atatgtagaa aatggtgaaa tattaaatca taagcctgca aaagcgaaaa aaggaacaga
    10321 tatacttgta gaatcattat tttataatac accagcacgt ttaaaatata ttaaaagttt
    10381 atacactgaa ctaggtaaaa taacagatat tgtcaacaga atggcaatga gccatccgga
    10441 cattcgaata gcactcattt cagatggcaa aacaatgtta agtacaaatg gttcaggacg
    10501 aactaatgaa gtgatggcag agatttatgg gatgaaagtt gcacgagatt tagtacatat
    10561 atctggagat acaagtgatt atcacattga aggttttgtt gcaaagcctg aacattctag
    10621 aagtaataag cactatattt ctatttttat taatggacga tacattaaaa actttatgct
    10681 aaataaagcg attttagaag gctatcatac actcttaaca ataggtaggt tcccgatttg
    10741 ttatattaat attgaaatgg atccaatctt agtagacgta aatgttcatc caacaaaact
    10801 agaagtgcgt ttatcaaaag aagagcaact ataccaattg attgtgagca aaatacaaga
    10861 agcatttaaa gaccgtatat taattcctaa aaataacttg gattatgtgc caaaaaaaaa
    10921 taaagtatta cattcattcg aacaacaaaa aatcgaattt gaacaaagac aaaacacaga
    10981 gaataaccaa gagaagacgt tttcatctga agaaagtaac agtaagccat ttatggaaga
    11041 aaatcaaaac gatgagatag ttataaaaga agattcatat aatccattcg taacgaaaac
    11101 atctgaaagt ttaatagctg atgatgaatc ttctggttat aataatacac gtgaaaaaga
    11161 tgaagactac ttcaaaaaac aacaagaaat tttacaagaa atggatcaaa catttgattc
    11221 aaatgatgat acaactgtgc aaaattatga gaataaagcg tctgatgatt attatgatgt
    11281 aaacgatatt aaaggaacaa aaagtaaaga ccctaaacga agaattccat atatggaaat
    11341 tgttggacaa gtacatggaa cgtatattat tgctcaaaat gaatttggca tgtacatgat
    11401 tgaccagcat gcagctcaag aaagaataaa atatgaatat tttcgagata aaataggtga
    11461 ggttaccaat gaagtacaag atttattaat cccgttaaca tttcattttt caaaagatga
    11521 acaattagtc attgatcaat ataaaaatga gcttcaacaa gtaggtatca tgttagaaca
    11581 ttttggtggt catgattata ttgtaagtag ctatccagtt tggttcccta aagatgaagt
    11641 agaagaaatt attaaagata tgattgagct aattttggaa gagaaaaaag tagatatcaa
    11701 aaaattacgt gaagatgtag caatcatgat gtcatgtaaa aaatccatta aagcgaatca
    11761 ttatttacaa aaacatgaaa tgtctgattt aattgatcaa ttaagagaag cggaagatcc
    11821 atttacatgt ccacatggtc gtccaataat cattaatttt tcaaaatacg aattagaaaa
    11881 attatttaag cgtgtgatgt agagaggatg aatcaagtga ataacaacat attgcctgct
    11941 ataagaaaca ttaaagattt agagaaactg attaaaacag attataaaat gtgtgtgctt
    12001 ctagatatgc atataggaca tataaaaagt attatggaat tgctgaagca aaatcatata
    12061 gagtgtttta ttcatataga tttgataaaa ggtttaagcc acgatgaatt tgcaagtgaa
    12121 tttattattc agcaatacaa gccaaaaggt atcgtatcga ctaaatctaa agtaataaaa
    12181 aaagctaaat cattaaatac tttaacgatt tttagagtat ttattattga tagtcaagca
    12241 ttgaaacgca gtatagattt gataaaaaaa gttgaacctg attttgttga agtacttcca
    12301 ggtgttgcga gtaaagcgat tcatcatatt cagaaagaaa caaacacaca agtcattgca
    12361 ggtggcctaa ttaatacaat agatgaagtc aatgaagctg ttaaaaatgg agcgaaatat
    12421 gtaacaacta gttatgataa actttggtaa atcataagtc tgcaaaaatt tcatttttca
    12481 cgagatttag tcatataaca taataaaaaa gccgttttca tatgggatat gcagtaggta
    12541 tcatacaaaa aataatcaaa taaaataatt agcacctcta aaacgattaa aatcattaaa
    12601 gttttagagg tgtttattat taaaaaatgc aactggtcat aaaaaatatg gctgaagaat
    12661 gtcaattaaa cataatggcg tcataaataa attagttagg attggtattt ctagttttca
    12721 aattaaacta cttttataaa gacttgaaaa attaaatttg acaaaatttt tacaaaaacc
    12781 attgacaacg ctttcatatc gatagtatca taacaaatat aataaaagtt aatacataga
    12841 atagagacgg gagatttcta cgagccaaac tgctagtgta ggaatctctt tgtctttttg
    12901 ggaggacatt taatatgaat gtatatttag cagaattcct aggaactgca atcttaatcc
    12961 tttttggtgg tggcgtttgt gccaatgtca atttaaagag aagtgctgcg aatggtgctg
    13021 attggattgt catcacagct ggatggggat tagcggttac aatgggtgtg tttgctgtcg
    13081 gtcaattctc aggtgcacat ttaaacccag cggtgtcttt agctcttgca ttagacggaa
    13141 gttttgattg gtcattagtt cctggttata ttgttgctca aatgttaggt gcaattgtcg
    13201 gagcaacaat tgtatggtta atgtacttgc cacattggaa agcgacagaa gaagctggcg
    13261 cgaaattagg tgttttctct acagcaccgg ctattaagaa ttactttgcc aactttttaa
    13321 gtgagattat cggaacaatg gcattaactt taggtatttt atttatcggt gtaaacaaaa
    13381 ttgccgatgg tttaaatcct ttaattgtcg gagcattaat tgttgcaatc ggattaagtt
    13441 taggcggtgc tactggttat gcaatcaacc cagcacgtga tttaggtccg agaattgcac
    13501 atgcgatttt accaatagct ggtaaaggtg gttcaaattg gtcatatgca atcgttccta
    13561 tcttaggacc aattgccggt ggtttattag gtgcagtggt atacgctgta ttttataaac
    13621 atacatttaa tattggttgt gcaattgcaa ttgttgtagt tattattact ttgattttag
    13681 gttacatttt aaataaatca tcaaaaaaag gtgatatcga atcaatttac taaaataaaa
    13741 agaaacgtaa atagcataat ttaacatgtt tgattcatgg attatgctat tttttcgcca
    13801 aaatttaaca gattttgtac aatgggttag cgattatttt ttaataaagg agatactact
    13861 aatggaaaaa tatattttat ctatagacca aggaacaaca agctcaagag cgattttatt
    13921 caatcaaaaa ggggaaattg caggggtagc acaacgtgag tttaagcaat attttccaca
    13981 atcaggttgg gttgaacatg atgcaaatga aatttggaca tctgtgttag ctgtaatgac
    14041 ggaagtaatt aatgaaaatg atgttagagc tgatcaaatt gcaggtatcg gtattacaaa
    14101 ccaacgtgaa acaacggttg tttgggacaa acatactggc cgcccaattt atcacgcaat
    14161 tgtttggcaa tcacgtcaaa cacaatcaat ttgttcagaa ttaaaacaac aaggatatga
    14221 acaaacattt agagataaga caggattact tttagatccg tattttgcag gtacaaaagt
    14281 taaatggatt ctagacaatg ttgaaggtgc acgagaaaaa gcagaaaatg gcgatctatt
    14341 atttggaacg attgatactt ggttagtatg gaaattatca ggaaaagctg cgcatattac
    14401 tgattattca aatgcgagtc gtacattaat gtttaatatc catgatttag aatgggacga
    14461 tgagttatta gaactactta cagtacctaa aaatatgttg ccagaagtta aagcttcgag
    14521 tgaagtatat ggtaagacaa ttgattacca cttctatggt caagaagtac caatcgctgg
    14581 agtagctggt gatcaacaag cagcattatt tggacaagct tgcttcgaac gtggtgacgt
    14641 gaaaaacaca tatggaactg gtggcttcat gttaatgaat acaggtgaca aagcggttaa
    14701 atctgaaagt ggtttattaa caacaattgc ttatggtatt gatggaaaag taaattatgc
    14761 gcttgaaggt tccatctttg tttcgggttc agcaatccaa tggttacgtg atggattaag
    14821 aatgattaat tcagcaccac aatcagaaag ttatgcgaca cgagttgact ctactgaggg
    14881 tgtttatgtt gttccagctt ttgtaggttt aggaacacca tattgggatt ctgaagcacg
    14941 tggtgcgatt ttcggtttaa cacgtggaac tgaaaaagag cactttatcc gtgcaacttt
    15001 agaatcatta tgttaccaaa ctcgtgacgt tatggaagca atgtcaaaag actctggtat
    15061 tgatgtccaa agtttacgtg tcgatggtgg tgcagttaaa aataacttta ttatgcagtt
    15121 ccaagcagac attgttaata cttctgttga aagacctgaa attcaagaaa ctacagcttt
    15181 aggtgctgca tttttagcag gattagcagt tggattctgg gagagtaaag atgatatcgc
    15241 taaaaactgg aaattagaag aaaaattcga tccgaaaatg gatgaaggcg aaagagaaaa
    15301 attatataga ggttggaaaa aagctgttga agcaacacaa gtttttaaaa cagaataaac
    15361 ttgtagatta gacttttgta taaacattgt gatacaatca atttaagtta atatttgaat
    15421 cgagaaacga gagatttgtt cgaacatgta caattgaagg attgtttatg tgggacaagt
    15481 ctctcgtttt tacatttttt aggaggcgtt ttggaatggc attgtctact tttaagagag
    15541 aacatattaa aaagaattta agaaatgatg aatatgattt agtaattatt ggtggcggta
    15601 ttacaggtgc aggtattgca ctagacgcga gtgaaagagg aatgaaagtt gcattagttg
    15661 aaatgcaaga ctttgcacaa ggaacaagct caagatctac aaaattagtc catggtggtt
    15721 tgcgttactt aaaacaattc caaattggag tagttgccga aactggtaaa gaacgtgcga
    15781 ttgtttatga aaatgggcct catgttacga ctccagagtg gatgctttta ccaatgcata
    15841 aaggtggaac atttggtaaa ttctcaacat caattggttt aggaatgtat gatcgtttag
    15901 caggtgttaa gaagtctgaa cgtaaaaaaa tgttatctaa aaaagaaact ttagctaaag
    15961 aaccattagt taaaaaagaa ggtctaaaag gcggcggtta ctatgttgaa tatcgtactg
    16021 acgatgcgcg tttaactatt gaagttatga agcgtgctgc tgaaaaaggc gcagaaatta
    16081 tcaactatac taagtctgaa cacttcactt atgataaaaa tcaacaagta aatggtgtta
    16141 aagttattga taaattaact aatgaaaatt atacaattaa ggctaaaaaa gtggttaatg
    16201 cagcaggtcc atgggttgat gatgttagaa gtggtgatta tgcacgcaat aataaaaaat
    16261 tacgtttaac taaaggtgta catgttgtta ttgatcaatc aaaattccca ttaggtcaag
    16321 cagtatactt tgatactgaa aaagatggaa gaatgatttt tgcaattcca cgtgaaggaa
    16381 aagcgtatgt aggtactaca gatacattct atgacaatat caaatcttca ccattaacta
    16441 cacaagaaga cagagactat ttaatcgatg cgattaatta catgttccct agtgttaatg
    16501 ttacagatga agatattgaa tcaacatggg caggaattag accattaatt tacgaagaag
    16561 gcaaagaccc ttctgaaatc tctcgtaagg atgaaatttg ggaaggtaaa tcaggtttat
    16621 taactattgc aggtggtaaa ttaacaggct atcgtcacat ggctcaagac attgttgatt
    16681 tagtatctaa acgcttgaaa aaagactacg gtttaacatt tagtccatgt aatacaaaag
    16741 gtctggcaat ttcaggtggc gatgtaggag gtagcaagaa ctttgatgcg tttgtagagc
    16801 aaaaagtaga tgtagctaaa ggattcggca ttgatgaaga tgttgcaaga cgtttagcat
    16861 ctaaatatgg ttcaaatgtt gatgaattgt tcaacattgc gcaaacatct caataccatg
    16921 atagcaagtt accattagaa atttatgtag aacttgttta tagtattcaa caagaaatgg
    16981 tatacaaacc taacgatttc ttagttcgtc gttctggtaa aatgtacttc aatattaaag
    17041 atgtattaga ttataaagat agtatcatcg atattatggc tgatatgtta gactactcac
    17101 cagctcaaat tgaggcttat actgaagaag ttgagcaagc aattaaagaa gcgcaacatg
    17161 gaaataatca gccagcagtt aaagaataat taatttgtac aatcataaac tggtgtcctg
    17221 ttttaggggc atcagttttt ttatatgaga tacattagtc aattgaaact atgcatcact
    17281 aaatgtatga taataataaa agcgaatata aaaacgttgt tattaaaggt gtgagatgat
    17341 gactgaaaaa caatttaaat taactgtaca agataacacg aatattgaag ttaaagtgaa
    17401 ttttacagat gtagattcaa aaggaattat tcatatattt catggtatgg ctgaacatat
    17461 ggaacgttac gataaattag cacatgcact ttcaaaggat ggcttcgatg tgatatgtca
    17521 taatcatcga ggacatggta ttaatattga tgaatcaaca agagggcatt acgatgatat
    17581 gaaacgagtt atcggtgatg cctttgaagt agcgcaaaca gtgagaggca atgttgataa
    17641 accatacatt ataatcggac attcaatggg atccgttata gctagattgt ttgtagaaac
    17701 atatccgcaa tatgttgatg gtctaatttt aagtgggaca gggatgtatc cattatggaa
    17761 aggattacca accgttaagg tgttacaact gattacaaaa atttatggtg ctgagaaacg
    17821 ggttgaatgg gttaaccagt tagtatcaaa tagttttaat aaaaaaatac gtccattacg
    17881 tacacaaagt gattggattt ctagtaatcc aactgaagta gacaacttta ttaaagatcc
    17941 atatagtgga tttaatgtgt caaatcaatt attatatcaa acagcctatt atatgctaca
    18001 tacatcacaa ttaaaaaata taaaaatgtt aaatcatgcc atgcctatat tattagtttc
    18061 aggatgtgac gatcctttag gtgattatgg taaagggatt ttaaaattgg cgaatatata
    18121 tagaaaagct ggcattaaaa atgttaaagt gaatctttat catcataaac gtcatgaagt
    18181 gttatttgaa aaagatcatg acaaaatttg ggaagacttg tttaaatggt tgaatcaatt
    18241 ttataaaaaa taaagaaagt ggaattaaat atgaataaaa ataagccttt tattgtagta
    18301 attgtggggc caactgcttc aggtaaaaca gagcttagca tagaactcgc gaagcgtatc
    18361 aatggtgaaa tcataagcgg tgattctatg caagtctaca aacatatgaa tattggaact
    18421 gcaaaagtaa cacctgaaga aatggatggt attccacatc atttaattga tatcttgaat
    18481 cctgatgata cattttcagc atatgaattc aagcgattag cagaagattt aattactgat
    18541 ataacgaata gaggtaaagt tccaatcata gcaggtggaa caggcttata tattcaatca
    18601 ttaatatata attatgaatt agaagatgaa acagttacac ctgcacaatt atccatagtt
    18661 aaacaaaagt tatctgcatt agaacattta gataatcagc aactacacga ttatttagat
    18721 caatttgatg cggtttctgc agaaaatatt caccctaaca accgccaaag agtgttgcgc
    18781 gctattgaat attatttaaa aacaaaaaaa cttttgagta atcgcaagaa agtgcaacaa
    18841 tttactgaaa attatgatac attattatta gggattgaaa tgtcgcgcaa aacattatat
    18901 tcaagaataa ataaacgtgt tgatattatg ttggatcacg gattatttag agaagtgcaa
    18961 caacttgttg aacaaggcta tgaatcttgc caaagtatgc aagctattgg atataaagaa
    19021 ttaatacctg tgattaacgg acaaatgatt tatgaagatg ctgtcaatga tttaaagcaa
    19081 cattcacgcc aatatgcaaa acgacaaatg acatggttca agaataaaat gagtgttcat
    19141 tggttagata aagaaaatat gtcacttcaa atgatgttag atgagattac aacccagatt
    19201 aagtaaaagg agtccgacag atgattgcaa acgaaaacat ccaagacaaa gcactagaga
    19261 attttaaagc aaaccaaact gaagtaactg tattctttct aaacggtttc caaatgaaag
    19321 gtgttattga agaatacgac aagtatgtcg taagcttaaa ttctcaaggc aaacaacact
    19381 tgatttacaa acatgcgatc agcacttata cagtagaaac tgaaggtcaa gcatctactg
    19441 aaagtgaaga ataagttgta atcatatggg cacgatttaa tgactcgtgt acataacgtt
    19501 tgaagtatga taaatagata tagaaataaa gtcatatgtg acatcaatta aatgatgttc
    19561 aaatgacaag atacaataga ggaatgtttg taataaaaac gcttcatata atggtcgagt
    19621 caatatatga tacgacttta tatgaagcgt tttatttgct atgagctagt atattttata
    19681 ataacttttc tatttctctt tcgatttgaa caggtttttt ttgaggtgca aatcgtttaa
    19741 caacgttacc ttcgcgatcc actaaaaact tagtgaaatt ccatttgatt ttctcattaa
    19801 agaatccatg ttgtgccgca gtcaaatatc taaataaagg taattgatgt tcccctttta
    19861 cgtctatttt ttgatgcata gggaaggtaa caccatagtt taatttacag ttttgagctg
    19921 cttcttcgcc tgatccaggt tcttggccac caaattgatt acaagggaaa cctagaatta
    19981 caaacccttg atctttgtat ttctcgtata atgattgcaa accttcaaat tgtgaagtaa
    20041 agccacattc gctagctgta ttaacaatta gcataacgtc acccttatat gcatctaatt
    20101 tgtaagtaac acctttattt gtttctacta caaaatcata aattgtctcc attgaatcat
    20161 cctttcgatt tacttaaaat gtaccataaa atcgtgtaat agtctttact aaaactctat
    20221 gatagaatac tttgagtagg attttattaa ggagatgtat aacatggctc agcaacaaat
    20281 tcatgatact aaaaataaac tagaaaaagc tgtcttagtc ggtgtacatg ctcaagatga
    20341 taagcaattt aattttgagt ctacaatgga ggaattatca tctttatcag agacttgcca
    20401 acttgaagtg ttgggtcaaa ttactcaaaa cagagatcgt gtagatcgca aatattatgt
    20461 tggtaaaggt aaaattgaag aaattcaagc atttattgag ttcaaagata ttgatgtagt
    20521 catcacaaat gatgaattaa cgactgcaca atccaaatca ctaaatgaag ctttaggtgt
    20581 aaaaattatt gatagaactc agttgattct tgaaatattt gcattaagag caagaagtaa
    20641 agaaggtaaa ttgcaagtag agctagcaca acttgattat ttattaccta gattgcaagg
    20701 ccatggtaaa agcctttctc gtttaggtgg cggtattgga actagaggcc ctggtgaaac
    20761 gaagttagag atggatcgca gacatattcg aactcgtatg aatgaaatta aacatcaatt
    20821 gcggacggta gaagaacatc gcgaaagata tcgaaataaa agaaatcaaa atcaggtgtt
    20881 tcaagtagct ttagttggtt atacaaatgc tggtaaatca tcatggttta atgttttagc
    20941 aaatgaagag acgtatgaaa aagatcaatt atttgcaacg ttagatccta aaacacgaca
    21001 aattcaaata aatgatggat ttaatttaat tatttcagat actgttggtt ttatacagaa
    21061 actacctacg acgttaattg cagcttttaa atcaacttta gaagaggcta aaggtgcgga
    21121 tttattagta catgtcgtag atagtagcca tcctgaatac cgtacacagt atgacacagt
    21181 taatgattta atcaaacaat tagatatgag tcatatttct caaatagtta tttttaataa
    21241 aaaggactta tgtgatcatg catcaaatcg tccagcaagt gatttgccta atgtttttgt
    21301 ttcttctaaa aatgatggtg ataaattact tgttaagacg ttatttattg atgaaatcaa
    21361 aaggcaatta acttattatg atgaggcaat tgcgacgaat aatgcagatc gattatattt
    21421 tctaaaacaa catacattag tgactgaact taaatatgat gaaattgaaa atgtttatcg
    21481 tataaaagga tttaaaaaat aataaaagga cgaaattcaa atgaaagata taagtaagat
    21541 agtagctgac gtcgaatcaa cgttagcacc atattttaaa gaaattgaag aaacagcata
    21601 tattaatcaa gaaaaagtat taaatgcgtt tcatcatgtc aaagcaaccg aaagtgattt
    21661 acaaggatca acaggttacg ggtatgatga ttttggacgt gaccatttag aagaaatata
    21721 tgcgcaggca tttaaagcag aagatgcaat tgttcgtccg caaattattt caggtacgca
    21781 tgcgattact attgcattac aaagtttatt aaaacatggt gatgaattaa tttatataac
    21841 gggtagtcca tatgacactt tacttgaagt cattggcgta aacggaaatg gtattgaaag
    21901 tttaatggag tacggcgtat cgtataaaga tattgcactt aaagaaggta aaatcgatat
    21961 tgaaagtgtg ttagatgggg tttctgagcg caccaaagta atagcgattc aacgttcgaa
    22021 aggctatgat caaagacctt caattcctct agatgaaatt gaacaggtga ttattaggtt
    22081 gaaagaagtg catcctaata ttttaatatt tgtggataac tgttatgggg aatttgtaga
    22141 aagacgtgaa cctatagaat gtggtgccga tttaatagca ggatcattaa ttaaaaaccc
    22201 tggcggtggt ttagctaaga ttggtggata cattgctggt agaaaagatt taattgaacg
    22261 atgtggttat agattgacag cacctggtat tggtaaagaa gcaggtgcat cattaaatgc
    22321 attgcttgaa atgtatcaag gtttcttttt agcaccacat gttgtcagtc agagtcttaa
    22381 aggggcattg tttactagtt tatttttaga aaaaatgaat atgaacacaa cgccgaagta
    22441 ctacgaaaaa cgaactgatt taattcaaac agttaaattt aaaacgaaag aacaaatgat
    22501 ttcattttgt caaagtattc aacacgcatc cccaattaat gcacatttta gtccagaacc
    22561 gagttatatg cctggttacg aagatgatgt tattatggct gctggtacgt ttattcaagg
    22621 ttcatcgatt gaattatctg cagatggacc tattcgtcct ccttatgaag cgtatgttca
    22681 aggaggatta acatatgaac acgttaaaat tgctgtgaca agagctgtta atcagttgaa
    22741 agaacaagga cttatataat agattaaatt tcaccctaaa tgataatgta ttttgggtga
    22801 aatttttttg cggagattta tcagattatt tttaaaaatt gaaaaaatat tttagctgta
    22861 gattgtttta tggcgtttta aaggtcaaaa ttgcagttat atcaatgttt tgagttttat
    22921 gtcagaaaac ctgacatatt tttgaaatcc taaaaaaatt atgataagtt attaacaagt
    22981 tcaaaagtag aggagaggaa caatgatatc gaatgatgca atcagacgaa atatggctgt
    23041 cttctctatg agtgtagtaa gtaaattaac ggatttaacg ccaaggcaaa tacgttacta
    23101 tgaaacacat gaactcatca aacctgaaag aacagaaggt caaaaacgtc tgttctcact
    23161 caatgatttg gaaagattac tagaaattaa atcactttta gaaaaaggat ttaatatcaa
    23221 agggattaaa caaatcattt atgactcaca agagcattta acaacagatg aacaagagat
    23281 aagaaaaaag atgattgtag atgccacgca aaagcctatt ggagaaactt taccaataaa
    23341 tcgtggtgat ttatcccgat ttattaaata aaatttggag gattttaaaa tgccaaaacg
    23401 tactttcact aaagacgaca ttcgtaaatt tgcagaagag gaaaatgtaa gatatttaag
    23461 attacaattc actgatattt taggaacaat taaaaatgtt gaagtgcctg taagccaatt
    23521 agaaaaagta cttgataacg aaatgatgtt tgacggttct tctatcgaag gtttcgtacg
    23581 tatcgaagaa tctgacatgt atttacatcc agatttagat acttgggtaa tcttcccatg
    23641 gactgctggt caaggtaaag tagcacgttt aatttgtgat gtatataaaa cagatggtac
    23701 gccatttgaa ggggatccac gtgcaaactt aaaacgtgta ttaaaagaaa tggaagattt
    23761 aggcttcaca gactttaacc tagggcctga accagaattc ttcttgttta agttggatga
    23821 aaaaggagaa ccaactttag aacttaatga tgatggtgga tatttcgatt tagcacctac
    23881 agatttagga gaaaactgtc gtcgtgatat tgttttagaa ttagaggata tgggcttcga
    23941 tattgaagct agtcaccatg aagttgcacc gggtcaacat gaaatcgact ttaaatatgc
    24001 ggatgcagtt acagcatgtg ataacatcca aacatttaaa ttggttgtta aaacaattgc
    24061 acgtaagcat aatttacatg caacattcat gcctaaacca ttatttggtg tgaacggtag
    24121 cggtatgcac tttaatgttt cattattcaa aggtaaagaa aatgcattct ttgatccgaa
    24181 tactgaaatg ggcttaacag aaacagctta ccaattcaca gctggtgtac ttaaaaacgc
    24241 acgtggattt acagcggtat gtaacccatt agtaaactca tacaaacgtt tagttcctgg
    24301 ttatgaagca ccatgttata ttgcatggag cggtaaaaac cgttcaccgt taatccgtgt
    24361 accatcttca agaggattat caactcgtat tgaagtacgt tcagttgacc cagctgcgaa
    24421 cccatatatg gcattagctg caattttaga agctggttta gacggtatta aaaataaatt
    24481 aaaagttcca gaacctgtta accaaaatat ttacgaaatg aatcgtgaag aacgtgaagc
    24541 agtaggcatt caagacttac cttcaacact ttacacagca ttaaaagcaa tgcgtgaaaa
    24601 tgaagttatt aaaaaagctt taggaaatca tatctataat caatttatta attcaaaatc
    24661 aattgaatgg gattactaca gaactcaagt atctgaatgg gaaagagatc agtacatgaa
    24721 gcaatattaa tacgctaaac aatgatggga aatcagtaat atcaagggct agagcgtttt
    24781 gctttagctc ttttttgatt tggaaagatg ggatttcact tgaccacttt tgttaaaaaa
    24841 tggatttggt caagttttgg tcaagtaaat gttttatgta tttatttttt taaagctggg
    24901 gaagaccatt ttatatttta gttcacatga attttaatat atttggaggt gatgagatga
    24961 ggcgataaaa gaacgtcgcg aaaacgttga gtattacttg aaaatagcca tattcatatt
    25021 acttctcatc gaattcattt gcagaacgtt ctaaggtaag accccgaaaa gagggacctt
    25081 actacgcatt attaaggggg taatactata tgaaaagaga aacaaaacaa aaaatatctt
    25141 tttgtttatc gatcggtatt ttcattttag ttatactact attgatattc taaaaaatta
    25201 aaaatttctc ctcatctaat ttatgaattg ctatgatgaa atattcaata caatcaaaga
    25261 attgatagaa aacaaagaga tatcgagtta tcaaattaat aaagatactg ggataagtta
    25321 cggtaatatt aatgctatgc gccgtagaga aagaagaata gaaaatttaa gcttaaagaa
    25381 tgcaaagatc ttatatgaat atgcgaaaaa ggtattgtaa tataagcatt gagttcaata
    25441 ggcatacaat aactgcccaa actagtgact gagtgggtgc ttttatagta ttaaaagttt
    25501 tctaaaagtg aaagaaatca tgtttagtga tttacttatg tttttcaaaa tagtataata
    25561 attttataca atatatagag cttcagtata ccttttgagt atatatggag ttctttcttt
    25621 tt
//
LOCUS       DAPSKH010000041        25524 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPSKH010000041 DAPSKH010000000
VERSION     DAPSKH010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 25524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25524
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.041"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..128
                     /gene="msa"
                     /locus_tag="RPH49_001753"
     CDS             <1..128
                     /gene="msa"
                     /locus_tag="RPH49_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sarA expression modulator protein Msa"
                     /protein_id="HDY5124895.1"
                     /translation="HIDVLITSKDFGFDEILFYTLYLLLILIVLYYLKKQVKNKN"
     gene            complement(369..1634)
                     /gene="lysA"
                     /locus_tag="RPH49_001754"
     CDS             complement(369..1634)
                     /gene="lysA"
                     /locus_tag="RPH49_001754"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDY5124896.1"
                     /translation="MTVKYNQNGELTMDGISLKTIAQSFGTPTIVYDELQIREQMRRY
                     HRAFKDSGLKYNISYASKAFTCIQMVKLVAEEDLQLDVVSEGELYTALEAGFEPNRIH
                     FHGNNKTKHEIRYALENNIGYFVIDSLEEIELIDRYANDTVQVVLRVNPGVEAHTHEF
                     IQTGQEDSKFGLSIQYGLAKKAIDKVQQSKHLKLKGVHCHIGSQIEGTEAFIETAKIV
                     LRWLKEQGIQVELLNLGGGFGIKYVEGDESFPIESGIKDITDAIKSEIKVLGIDAPEI
                     GIEPGRSIVGEAGVTLYEVGTIKEIPGINKYVSIDGGMSDHIRTALYDAKYQALLVNR
                     NEKADDSVTIAGKLCESGDIIIKDAKLPSSVKRGDYLAILSTGAYHYSMASNYNQMQK
                     PSVFFLKDGKAREVIKRQSLRQLIINDIK"
     gene            complement(1624..2709)
                     /locus_tag="RPH49_001755"
     CDS             complement(1624..2709)
                     /locus_tag="RPH49_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDY5124897.1"
                     /translation="MTATWSVNKKIFLQNAITVKNNQPLMAVVKNNAYHYDLEFAVTQ
                     FIHAGIDTFSTTSLREAIQIRQLAPDATIFLMNAVYEFDLVREHQIHMTLPSLTYYYK
                     HKNDLAGIHVHLEFENLLHRSGFKDLNEIKEVLKDHHHNQNAKMIISGLWTHFGYADE
                     FDVSDYNVERSQWMEIVEALLSEGYQFDLIHAQNSASFYREGQILLPHHTHARVGIAL
                     YGSRPYSSLNQHDIVQSLTVKAHVIQVREVQAGDYCGYSFAFEVTKNNTKLAVVDIGY
                     GDGILRTRAKHEALINGKRYPIRALMMSHMFVEVDGNVHAQDEVILYNNDIRIDEYTF
                     KGVGANSEQLSAMNHDSLKKEYISNDC"
     gene            complement(2714..3865)
                     /locus_tag="RPH49_001756"
     CDS             complement(2714..3865)
                     /locus_tag="RPH49_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDY5124898.1"
                     /translation="MNELEFVTKHRRHLHQHPELSLHEFETTAYIKAFLDSLNIKYDC
                     PLETGVIAYLEGNGSHTIAYRADIDALPILEENDVPYRSQSDHVMHACGHDGHTTALM
                     LFVQRCKDMQDASQLPQNVVFIFQPAEETGGGANRLIKAGAFDKYPIEAVFGIHVNPF
                     ADEGIAVIRDEEITASATEYRFFLTGLSSHVADKEQGHSCGEALQHVLTQISQIQQFH
                     LNGLKRNIVHIGHFKAGEAINTVPSNGYLEGTIRTYDIDDLTIVKNQMHKIAESVKLL
                     FNVDCEVKFAEGYPPTINSPKLRTQIEDALIKADLNVYDKPTPFLFGEDFSFYGQQLA
                     PAYFVFIGTRNEDKGFVTGLHTSHLNFDEKVLINVVNFYENLLNNYKEV"
     gene            complement(4008..4727)
                     /gene="dapD"
                     /locus_tag="RPH49_001757"
     CDS             complement(4008..4727)
                     /gene="dapD"
                     /locus_tag="RPH49_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDY5124899.1"
                     /translation="MVQHLTAEEIIQYISDAKKSTPIKVYLNGNFEGITYPESFKVFG
                     SEQSKVIFCEADDWKPFYEAYGSQFEDIEIEMDRRNSAIPLKDLTNTNARIEPGAFIR
                     EQAIIEDGAVVMMGATINIGAVVGEGTMIDMNATLGGRATTGKNVHVGAGAVLAGVIE
                     PPSASPVIIEDDVLIGANAVILEGVRVGKGAIVAAGAIVTQDVPAGAVVAGTPAKVIK
                     QASEVQDTKKEIVAALRKLND"
     gene            complement(4754..5476)
                     /locus_tag="RPH49_001758"
     CDS             complement(4754..5476)
                     /locus_tag="RPH49_001758"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDY5124900.1"
                     /translation="MKILLIGYGAMNQRVARLAEEKGHEIVGVIENTPKATTPYQQYQ
                     HIADVKDADVAIDFSNPNLLFPLLDEEFHLPLVVATTGEKEKLLNKLDELSQNMPVFF
                     SANMSYGVYALTKILAAAVPLLDDFDIELTEAHHNKKVDAPSGTLEKLYDVIVSLKEN
                     VTPVYDRHELNEKRQPQDIGIHSIRGGTIVGEHEVLFAGTDETIQITHRAQSKDIFAN
                     GAIQAAERLVNKPNGLYTFDNL"
     gene            complement(5473..6360)
                     /locus_tag="RPH49_001759"
     CDS             complement(5473..6360)
                     /locus_tag="RPH49_001759"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDY5124901.1"
                     /translation="MTHLFEGVGVALTTPFTNNKVNLEALKAHVNFLLENNAQAIIVN
                     GTTAESPTLTTDEKERILKAVIDLVDKRVPVIAGTGTNDTEKSIQTSIQAKALGADAI
                     MLITPYYNKTNQRGLVKHFEAIADAVKLPVVLYNVPSRTNMTIEPETVETLSQHPYIV
                     ALKDATNDFEYLEEVKKRIDTNVFALYSGNDDNVVEYYQRGGQGVISVIANVIPKEFQ
                     ALYDAQQSGLDIQDQFKPIGTLLSALSVDINPIPIKALTSYLGFGNYELRLPLVSLED
                     TDTKVLREAYDTFKAGENE"
     gene            complement(6362..7351)
                     /locus_tag="RPH49_001760"
     CDS             complement(6362..7351)
                     /locus_tag="RPH49_001760"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDY5124902.1"
                     /translation="MTKLAVVGATGLVGTKMLETLNRKNIPFDELVLFSSARSAGQEV
                     EFQEKTYTVQELTDARASEHFDYVLMSAGGGTSEHFAPLFEKAGAIVIDNSSQWRMAE
                     DIDLIVPEVNEPTFTRGIIANPNCSTIQSVVPLKVLQDAYGLKRVAYTTYQAVSGSGM
                     KGKKDLAEGVNGKAPEAYPHPIYNNVLPHIDVFLENGYTKEEQKMIDETRKILNAPDL
                     KVTATCARVPVQDSHSVEIDVTLDKEATAEDIKALFDQDDRVVLVDNPENNEYPMAIN
                     STNKDEVFVGRIRRDDSLENTFHVWCTSDNLLKGAALNAVQVLEQVMRLKGAN"
     gene            complement(7415..8620)
                     /locus_tag="RPH49_001761"
     CDS             complement(7415..8620)
                     /locus_tag="RPH49_001761"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDY5124903.1"
                     /translation="MVTRSVLKFGGSSVSDFTKIKRIAEMLKERVNQDEQLIVVVSAM
                     GNTTDQLMTNVSTLTKAPKQQELALLLTTGEQQTVSYLSMVLNDIGVNAKAMTGYQAG
                     IKTIGHHLKSKIAQINPQTFEQVFQENDILVVAGFQGINEHQELTTLGRGGSDTTAVA
                     LAVSNQIPCEIYTDVDGVYATDPRLLPKAKRLDIVSYEEMMEMSALGAGVLETRSVEL
                     AKNYNIPLYLGKTLSNVKGTWIMSNEEILEKKAVTGVALDKHMMHVTISYPLPDNQLL
                     TQLFTELEEGAVNVDMISQIVNLDGLQLSFTIKDSDFHQISMILETLKNQYEALAYKI
                     NEHYVKISLIGSGMRDMSGVASKAFLTLIENNIPFYQTTTSEISISYVIDDFNGQQAV
                     EKLYDAFNI"
     gene            complement(9480..11081)
                     /locus_tag="RPH49_001762"
     CDS             complement(9480..11081)
                     /locus_tag="RPH49_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDY5124904.1"
                     /translation="MLQVTDVSLRFGDRKLFEDVNIKFTEGNCYGLIGANGAGKSTFL
                     KILSGELDSQTGHVSLGKNERLAVLKQDHYAYEDERVLDVVIKGHERLYEVMKEKDEI
                     YMKPDFSDEDGIRAAELEGEFAEMNGWNAEADAANLLSGLGIDPTLHDKKMAELENNQ
                     KIKVLLAQSLFGEPDVLLLDEPTNGLDIPAISWLEDFLINFDNTVIVVSHDRHFLNNV
                     CTHIADLDFGKIKVYVGNYDFWYQSSQLAQKMAQEQNKKKEEKMKELQDFIARFSANA
                     SKSKQATSRKKQLEKIELDDIQPSSRRYPFVKFTPEREIGNDLLIVQNLSKTIDGEKV
                     LDNVSFTMNPNDKAILIGDSEIAKTTLLKILAGEMEPDEGSFKWGVTTSLSYFPKDNS
                     EFFEGVNMNLVDWLRQYAPEDEQTETFLRGFLGRMLFSGEEVKKKASVLSGGEKVRCM
                     LSKMMLSSANVLLLDEPTNHLDLESITAVNDGLKSFKGSIIFTSYDFEFINTIANRVI
                     DLNKQGGVSKEIPYEEYLQEIGVLK"
     gene            11228..12130
                     /gene="cvfB"
                     /locus_tag="RPH49_001763"
     CDS             11228..12130
                     /gene="cvfB"
                     /locus_tag="RPH49_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HDY5124905.1"
                     /translation="MALDKDIVGSIEFLEVVGLQGSTYLLKGPNGENVKLNQSEMNDD
                     DELEVGEEYSFFIYPNRSGELFATQNMPDITKDKYDFAKVLKTDRDGARIDVGLPREV
                     LVPWEDLPKVKSLWPQLGDHLLVTLRIDRENHMYGRLASESVVENMFTPVHDDNLKNE
                     VIEAKPYRVLRIGSFLLSESGYKIFVHESERKAEPRLGESVQVRIIGHNDKGELNGSF
                     LPLAHERLDDDGQVIFDLLVEYDGELPFWDKSSPEAIKEVFNMSKGSFKRAIGHLYKQ
                     KIINIETGKITLTKKGWSRIDSKE"
     gene            12443..13426
                     /locus_tag="RPH49_001764"
     CDS             12443..13426
                     /locus_tag="RPH49_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDY5124906.1"
                     /translation="MKKWQFVGTTALGATLLLGACGGGNGGSGNSDLKGEAKGDGSST
                     VAPIVEKLNEKWAQDHSDAKISAGQAGTGAGFQKFIAGDIDFADASRPIKDEEKQKLQ
                     DKNIKYKEFKIAQDGVTVAVNKENDFVDELDKQQLKAIYSGKAKTWKDVNSKWPDKKI
                     NAVSPNSSHGTYDFFENEVMNKEDIKAEKNADTNAIVSSVTKNKEGIGYFGYNFYVQN
                     KDKLKEVKIKDENGKATEPTKKTIQDNSYALSRPLFIYVNEKALKDNKVMSEFIKFVL
                     EDKGKAAEEAGYVAAPEKTYKSQLDDLKAFIDKNQKSDDKKSDDKKSEDKK"
     gene            13617..14543
                     /gene="pstC"
                     /locus_tag="RPH49_001765"
     CDS             13617..14543
                     /gene="pstC"
                     /locus_tag="RPH49_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDY5124907.1"
                     /translation="MTSSTNVKALIEKNNNKKGKHNDKIIPVILAAISAISILTTLGI
                     LITLLLETITFFTRIPITEFLFSTTWNPTGSDPKFGIWALIIGTLKITVIATIFAVPV
                     GLGAAIYLSEYASDRARRIIKPILEILAGIPTIVFGFFALTFVTPVLRSFIPGLGEFN
                     AISPGLVVGIMIVPLITSLSEDAMASVPNKIREGAYGLGATKLEVATKVVLPAATSGI
                     VASIVLAISRAIGETMIVSLAAGSSPTASLSLTSSIQTMTGYIVEIATGDATFGSNIY
                     YSIYAVGFTLFIFTLIMNLLSQWISKRFREEY"
     gene            14545..15462
                     /gene="pstA"
                     /locus_tag="RPH49_001766"
     CDS             14545..15462
                     /gene="pstA"
                     /locus_tag="RPH49_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDY5124908.1"
                     /translation="MEMTDNNRQSLVDQQLVQKHLSSRTVKNKVFKLIFLACTLLGLV
                     VLIALLTQTLIKGVSHLNLQFFTNFSSSTPSMAGVKGALIGSLWLMLSIIPLSIILGI
                     GTAIYLEEYAKNNKFTQFVKISISNLAGVPSVVFGLLGYTLFVGGAGIEALKMGNSIL
                     AAALTMTLLILPIIIVSSQEAIRAVPNSVREASYGLGANKWQTIRRVVLPAALPGILT
                     GFILSLSRALGETAPLVLIGIPTILLATPRSILDQFSALPIQIFTWAKMPQEEFQNVA
                     SAGIIVLLVILILMNGVAIILRNKFSKKF"
     gene            15509..16360
                     /locus_tag="RPH49_001767"
     CDS             15509..16360
                     /locus_tag="RPH49_001767"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDY5124909.1"
                     /translation="MAQTLAQTKQISQSHTFDVSQSHHKTPDDTNSHSVIYSTQNLDL
                     WYGENHALQNINLDIYENEITAIIGPSGCGKSTYIKTLNRMVELVPTVKTAGKILYRD
                     QDIFDQKYSKEQLRTNVGMVFQQPNPFPKSIYDNITYGPKIHGIKNKKVLDEIVEKSL
                     RGAAIWDELKDRLHTNAYSLSGGQQQRVCIARCLAIEPEVILMDEPTSALDPISTLRV
                     EELVQELKEKYTIIMVTHNMQQAVRVSDKTAFFLNGYVNEYDDTDKIFSNPSNKKTED
                     YISGRFG"
     gene            16367..17008
                     /gene="phoU"
                     /locus_tag="RPH49_001768"
     CDS             16367..17008
                     /gene="phoU"
                     /locus_tag="RPH49_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDY5124910.1"
                     /translation="MAIIRQRYQEQLDDLIKELRRLGANVYVSIENGIKSLSIDDRGF
                     ARQTVKNDKHINQLNYNINERVIMLITKQQPIASDLRMMISSLKIASDLERIGDNASS
                     IANIRLRTKITDDYVLTRLKTMGKLAMLMLKDLDQAFKKKDTVLIREIIERDEDIDDL
                     YSHIINATYLIDNDPFVAAQAHLAARHLERIGDHIINIAESVYFYLTGTHYEQ"
     gene            complement(17151..18965)
                     /gene="pepF"
                     /locus_tag="RPH49_001769"
     CDS             complement(17151..18965)
                     /gene="pepF"
                     /locus_tag="RPH49_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDY5124911.1"
                     /translation="MSQGLLLREDVPVSETWDLVDLFKDDQQYYESIDALVQQANQFH
                     HTYATTLNSIEQINTALAELENILIALDRLSNYAELRLSVDTSNIEAQVLSAKLSTTY
                     GKIVSQLSFVESEILELPEEILQQLEESCPYQHYIKQLIKQKPFQLSASVEQVLATLS
                     PTLNSPYDLYGTTKMLDITFDSFEHDGTTYPVDYATFENDYEDNKDPEFRRKSFKSFS
                     DGIRKYQHTTAATYNMQVQQEKIEADLRGFESVIDYLLHSQEVTRDMFDRQIDMIMRD
                     LAPVMQKYAKLLQRIHELDNMRFEDLKISVDPDYEPEISIEDSKNYIFGALSVLGDDY
                     TNMLREAYDQRWIDFAQNKGKDTGAFCASPYFTHSYVFISWTGKMAEAFVLAHELGHA
                     GHFTSAQKHQPYLESEASMYFVEAPSTMNEMLMANYLFNTSDNPRFKRWVIGSILSRT
                     YYHNMVTHLLEAAYQREVYHKVDQGESLNAPTLNEIMLNVYKQFFGDVVDMTEGAELT
                     WMRQPHYYMGLYSYTYSAGLTIGTVVSQKIKNEGQQAVDAWLETLKKGGSVSPVELAN
                     IAGVDITTEQPLKSTIQYISDLVDEVEKLTDEIEQANN"
     gene            19170..19514
                     /locus_tag="RPH49_001770"
     CDS             19170..19514
                     /locus_tag="RPH49_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124912.1"
                     /translation="MTLFDMPNYLWITTLIMILLTIFCCLVLNKWFVSAVITFVILGV
                     LAFFIPNFQDIKYQPLLGYAAFLAIMSLLISFLLWYFTRNWRKERKARKLEKQIEKYG
                     YEGAELRRKDKK"
     gene            19462..19647
                     /locus_tag="RPH49_001771"
     CDS             19462..19647
                     /locus_tag="RPH49_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124913.1"
                     /translation="MKNTAMRALNFAVKIKNNIRQLYAQNHRLLSYTAVTIISKEMEY
                     SAIVVFVLTFLYFTWLT"
     gene            19818..20804
                     /locus_tag="RPH49_001772"
     CDS             19818..20804
                     /locus_tag="RPH49_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124914.1"
                     /translation="MFIIKSMMYRLIQMIVVLFVISTLTFILMKLSPGNPVDKILHLD
                     VAQVSTEQINATKDKLGLNDSLLVQWWHWMNHLLHFNLGKSFESKEPVTQILFNYAPI
                     TLLISFSTLVVSLCISIPLGIIAAKRFHKWTDKVIRVISTLSISLPAFFIGIILLFIV
                     TNLMNIDSVILSQFILPVLTLSLGMCAYIIRFVRSNLLMLLQSNIVQASRLRGMNERY
                     ILIHDLLKPTIFPIIPLLGISLGSLIGGTVVIENLFDIPGIGYLLMDSIKSRDYPVIQ
                     GCVLFIGFFVVIINTIADLLTLLLDPKQRLQLGNPKNKTNTPLISEGSDRHA"
     gene            20797..21627
                     /locus_tag="RPH49_001773"
     CDS             20797..21627
                     /locus_tag="RPH49_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5124915.1"
                     /translation="MHKIFSKNNLIFFVFVAFIFVVIVLQFFVSSENTTKVNLSQTFE
                     PISWLHLLGTDDYGRDLFTRIIIGARSTLFVTVLTLIAIVVIGVTLGLFAGYKKGWIE
                     RLVLRFIDVGLSIPEFIIMIALASFFQPSLWNLVISIAVIKWMNYTRLTRSIVNSEMN
                     KPYIKMAQLFHVPTRTILIRHLTPKIIPAIIVLMVVDFGKIILYISSLSFIGLGAQPP
                     TPEWGAMLQQGRDFISSHPIMLIAPASVIAITILIFNLTGDTLRDRLLKQRGEYDESH
                     "
     gene            21614..22387
                     /locus_tag="RPH49_001774"
     CDS             21614..22387
                     /locus_tag="RPH49_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5124916.1"
                     /translation="MSLIDIQNLTIKNTSEKSLIKGIDLKIFSQRINALIGESGAGKS
                     LIAKALLEYLPFDLTCTYDSYQFDGENVSKLSQYYGHTIGYISQNYAESFNDHTKLGK
                     QLTAIYRKHYKNSKEEALSKIDKALSWVNLQSKDILNKYSFQLSGGQLERVYIASVLM
                     LEPKLIIADEPVASLDALNGNQVMDLLQHIVLEHGQTLFIITHNLSHVLKYCQYINVL
                     KEGQIIERGNINHFKYEHLHPYTERLIKYRTQLKRDYYD"
     gene            22380..23085
                     /locus_tag="RPH49_001775"
                     /pseudo
     CDS             22380..23085
                     /locus_tag="RPH49_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499904.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            23209..23682
                     /locus_tag="RPH49_001776"
     CDS             23209..23682
                     /locus_tag="RPH49_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDY5124917.1"
                     /translation="MGLLDIASIRSIERGFNYYQSECVINLKSFSETQHEAEVKGSGN
                     KVYRCYIDMEHPRKSKCNCPHADGRRVICKHMIALLFTASPEAANKHIIMLNEVEEDY
                     HLRRNMWIDSLKEMINDMSEEELRDAYLNMLIEHGEMAELFGLDEEDEMFEDEFY"
     gene            complement(23731..24498)
                     /locus_tag="RPH49_001777"
     CDS             complement(23731..24498)
                     /locus_tag="RPH49_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDY5124918.1"
                     /translation="MRFVFDIDGTLCFDGRLIDQTIIDTLLQLQHDGHELIFASARPI
                     RDLLPVLPSVFHRHTLIGANGAMISQQSKISVIKPIHTDTYHHILKIIQKYELDFIID
                     DDWNYAAQLDAENAIFERLDPHKLASCIDVANIDTPIKVILLNIDPAQITTILDELNK
                     YHQELEMIHHSNEYNIDITAQNINKYTALQYIFDADVKYIAFGNDHNDIVMLQHASSG
                     YIIGPSEAYTHAILKLDKIKHINNNAQAICKVLKSYK"
     gene            complement(24748..25494)
                     /locus_tag="RPH49_001778"
     CDS             complement(24748..25494)
                     /locus_tag="RPH49_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001558444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124919.1"
                     /translation="MNRIEKHAKNTFIILMLIMLFWIFMSFIFQKLLFPPSKNNLTTY
                     EALKYYTHLKGYYGLDHISKGIAYIACVLIPLNFFFRFNDIKKDNNYNNIISTLFLLL
                     YFLVNGISLIIQGYTAEFTISLISKANIHNNHEFAVNLFRYVIQEGGISFSTYLVCNF
                     CIIMWLLFSCSLLKERKPVVRCLPLIISCLKLILILLFLLSILLVIYQTQSAQILFVF
                     IDFLNFVALILVYLCTNPNNRSIDKIACVK"
BASE COUNT         8453 a         4186 c         4139 g         8746 t
ORIGIN      
        1 aacatattga tgtattaatt acaagtaaag attttggatt tgatgaaatt ctgttttata
       61 cattatattt gttgttaatt cttatcgttt tatattattt gaaaaagcaa gtaaagaata
      121 aaaactaatt tcatgatgct tgtttaaagt gtggtatgta aatgatgctt taaattagtt
      181 gaatagggct aactaaatat aaaggattaa tgacaaaaag aaataaatac tttctaacta
      241 aaaaagtgct gttcttcctt ttttagagta tatgtccaag catgttatct acagtcatcc
      301 tataatgcat aaaaattccc cgagtcacag tataattttc tgtgcttcgg ggattacttt
      361 gtttattttt attttatatc attaataatg agttgtctta acgattgtcg ctttataact
      421 tcacgtgctt tgccatcttt taagaaaaac acagaaggct tttgcatttg attgtaattg
      481 gatgccatag agtaatgata tgcaccagtt gataatatag caagatagtc tccacgtttg
      541 actgatgaag gtaatttagc gtctttaata atgatatcac cagactcgca taattttcca
      601 gctatagtta cactgtcatc tgctttttca tttctattaa caagcaatgc ttgatacttt
      661 gcgtcataaa gtgcagttct gatatgatca ctcataccgc catcgataga aacatattta
      721 ttaatccctg gaatttcttt aatggttcca acttcatata aagtaacgcc agcttcacct
      781 acaatagatc gtcctggttc aatacctatt tctggtgcat ctatacctag aactttaatt
      841 tcggatttta ttgcgtctgt aatatcttta ataccacttt cgatagggaa actttcatca
      901 ccttcaacat atttaatacc aaagccacca ccaaggttta ataattcaac ttgaatgcct
      961 tgctctttaa gccaacgtaa aacaatttta gcagtttcaa taaatgcttc tgtaccttca
     1021 atctgtgaac caatatgaca atgtacacct tttaatttta agtgtttaga ttgttggact
     1081 ttgtcaattg cttttttagc taagccatat tgaattgata acccaaactt actatcttct
     1141 tgaccagttt gaataaattc gtgtgtatgt gcttcaacac ctggattaac tcgtaataca
     1201 acttgaaccg tatcattagc atagcggtct attaattcaa tttcttctaa tgaatctata
     1261 acaaaataac cgatgttatt ttctaaagca tacctaattt catgtttcgt tttattgtta
     1321 ccatggaaat ggatgcgatt cggttcaaaa cctgcttcta aagctgtata taattcacct
     1381 tcagaaacaa catctaactg taaatcttcc tcagctacaa gtttgaccat ttgaatgcaa
     1441 gtaaatgcct ttgaggcgta tgaaatattg tattttaatc cactatcttt aaatgcgcga
     1501 tggtaacggc gcatctgttc tctaatttgt agttcatcat aaacaatggt aggtgtacca
     1561 aagctttgcg caatcgtttt taaactaata ccatccattg ttaattcgcc attttgatta
     1621 tatttaacag tcatttgaaa tgtactcctt ttttaaagaa tcatgattca tagcacttaa
     1681 ttgttcagaa tttgcaccaa cacctttaaa ggtatattca tcgatgcgga tatcattatt
     1741 ataaagaata acttcatctt gtgcatgtac attgccatct acttcaacaa acatatggct
     1801 catcattaat gcacgtatcg ggtagcgttt accattgata agtgcttcat gtttagcacg
     1861 agttcttaaa attccatcgc cataaccgat atcaactaca gctaattttg tattgttttt
     1921 agtcacttca aaggcaaagc tataaccgca ataatcacca gcttgtactt cgcgcacttg
     1981 aataacatgt gcttttacag ttaatgactg aactatatca tgttgattca gtgaactata
     2041 tggtcttgaa ccgtataacg caatacctac acgcgcatgt gtatggtggg gtagtaatat
     2101 ttgtccttcc cgataaaaac tcgcactatt ttgagcatgg attaggtcga actgataacc
     2161 ttcagataaa agtgcttcaa caatttccat ccattgtgaa cgttcaacat tataatctga
     2221 cacatcgaat tcatcagcat atccaaaatg ggtccataaa ccactaataa tcatttttgc
     2281 gttttgatta tgatggtgat ctttcaatac ttctttaatt tcgtttaaat ctttaaatcc
     2341 agaccgatgt aataaatttt caaattctaa gtgaacatga atacctgcta aatcattttt
     2401 atgcttatag taatatgtca acgacggcaa agtcatgtgt atttgatgtt cacggactaa
     2461 atcaaactcg taaactgcat tcattaaaaa gattgttgca tctggagcaa gttgtctaat
     2521 ttgaattgct tctcgtagtg atgttgtgct aaatgtatct atacctgcat ggataaactg
     2581 agttacagca aattctaggt catagtgata tgcattattt ttaacaactg ccattaatgg
     2641 ctgattgttt ttgactgtga ttgcattttg taaaaatatt ttcttattta cagaccatgt
     2701 tgctgtcaat gtattacacc tctttgtaat tatttaataa attttcgtaa aaattaacca
     2761 cgtttattaa cactttttca tcaaaattta aatgtgatgt gtgcaaacca gttacaaaac
     2821 ctttatcttc atttcgtgtt cctataaaaa caaagtaagc tggagctagt tgttgaccat
     2881 aaaaactaaa atcttcccca aataagaatg gcgttggttt gtcatagaca tttaaatcag
     2941 cttttattaa ggcgtcctct atttgagtac gtaatttcgg actattgatt gtagggggat
     3001 aaccttctgc aaatttaact tcacaatcta cattaaacag aagcttgaca ctttctgcta
     3061 tcttgtgcat ttgattttta acgattgtta aatcatcaat atcatatgta cgaatagtac
     3121 cttctaaata accattactt ggtacagtgt taatcgcttc accagcttta aaatgaccaa
     3181 tatgaacaat atttcgtttc aaaccgttaa ggtgaaattg ttgaatttgt gatatttgag
     3241 ttaatacatg ttgtaatgct tcaccacaag aatgaccttg ttctttatca gcaacatgac
     3301 ttgacaggcc tgttaagaaa aagcgatact ctgttgcgct ggccgtaatt tcttcatctc
     3361 ttatcactgc aatgccttca tcagcaaatg ggttaacatg aataccaaat accgcttcaa
     3421 ttggatactt atcaaaggca ccggctttta ttaatcgatt tgcaccgcca ccagtttctt
     3481 ctgcaggttg gaaaatgaaa acgacatttt gcggtaattg acttgcatct tgcatgtctt
     3541 tgcaacgttg tacaaaaagc attaatgcag ttgtatgacc atcatgtcca caagcatgca
     3601 tcacatgatc agattgactg cgataaggca catcattttc ctctaaaata ggtaacgcat
     3661 caatatcagc tctatacgct atcgtatgtg agccattacc ttctaagtat gcaatgacgc
     3721 cagtttccaa tgggcaatcg tatttaatat ttaaactatc taaaaacgct ttaatataag
     3781 cagttgtttc aaattcatgt aagcttaatt caggatgttg atgtaaatga cggcgatgtt
     3841 tcgtaacaaa ttctaattca ttcataatta tcaatccttt gtgttaaatt actatataaa
     3901 tagtgtaacg tatttcgaaa tttgtgatca taagtttatt caatgataaa caataaggtt
     3961 gagacataat cgtatctcaa ccttgaaatt attatacgtt gacgtcacta gtcatttagt
     4021 tttcttaatg ctgctacaat ttctttttta gtatcttgta cttcagaagc ttgcttaatc
     4081 acttttgcag gtgtaccagc aacaactgca ccagctggta catcttgtgt cacaatcgca
     4141 ccagctgcaa caatagcacc tttaccaaca cgtacacctt ctaaaataac tgcatttgca
     4201 ccgattaaaa catcatcctc gattataact ggtgaagcac tagggggttc aatcacacct
     4261 gctaatactg cgccagcccc tacatgtaca tttttaccag ttgtagcacg accaccgaga
     4321 gtagcattca tatcaatcat tgtaccttcg ccaacgactg cgccaatatt aattgttgcg
     4381 cccatcataa cgacagcacc atcttcaata atggcttgtt ctctaataaa cgcacctggt
     4441 tcaattcgtg cattcgtatt tgttaagtct tttaatggaa tggcagaatt gcgacgatcc
     4501 atttcaattt ctatatcttc gaattgacta ccatatgctt cgtaaaaagg tttccaatca
     4561 tctgcttcac aaaagattac ttttgattgt tctgaaccaa atactttaaa actttctgga
     4621 tatgtgatgc cttcaaaatt cccatttaaa tatactttaa ttggtgtaga ttttttagca
     4681 tcacttatat attgaataat ttcttcagct gttaaatgtt gtaccataaa ataatcgatc
     4741 tcctttaata tgtttatagg ttgtcaaacg tatataagcc gtttggttta ttaactaagc
     4801 gttctgctgc ttgtattgca ccattcgcaa aaatatcttt tgattgtgca cgatgcgtga
     4861 tttgaatcgt ttcatcagtg ccggcaaata gaacttcatg ttcaccgaca atcgtacctc
     4921 cacgaataga atgtatacca atatcttgtg gctggcgttt ttcatttaat tcatgtctat
     4981 catacacagg tgttacattt tctttcaaag atacaatcac gtcatataat ttttctaacg
     5041 taccacttgg tgcatctact tttttattat gatgtgcctc agtcaattcg atatcgaaat
     5101 catcaagtag gggaacagca gctgctaaaa ttttagtcaa tgcataaacg ccataactca
     5161 tgttcgcgct gaaaaataca ggcatatttt gactcaattc atctaactta ttaagtagtt
     5221 tttctttctc gccagttgtt gctaccacta atggcaaatg aaactcttca tctaataatg
     5281 ggaataatag attcggattt gaaaaatcta ttgcaacatc ggcatcttta acatctgcaa
     5341 tatgttgata ttgttgatat ggcgttgttg ctttcggtgt attttcaatg accccaacaa
     5401 tttcatggcc tttttcttct gctaatctag caacgcgttg attcattgcg ccatagccaa
     5461 ttagtaatat cttcactcat tttcacccgc cttaaatgtg tcatatgctt cacgaagcac
     5521 tttagtatct gtatcttcta ggctaaccaa tggtaaacgt aattcatagt ttccaaatcc
     5581 taaataactt gttaaagctt taataggaat tgggttaata tcaactgata gggctgataa
     5641 cagtgtgccg attggtttaa attgatcttg aatatctaat ccgctttgtt gagcatcgta
     5701 taacgcttga aattctttag gaatgacatt agcaatgaca gaaataacgc cttgaccacc
     5761 acgttgatag tattctacaa cattgtcatc attgccacta tataaagcaa atacattggt
     5821 atcaatgcgc tttttcactt cttctaaata ctcaaaatca ttcgtagcat cttttaaagc
     5881 aactatataa ggatgttgac ttaatgtttc gactgtttct ggttcaatcg tcatatttgt
     5941 tcttgatggc acattgtaca gcacgactgg taatttcaca gcatctgcaa tcgcttcaaa
     6001 gtgtttgact aaaccacgtt ggttcgtttt gttgtagtag ggcgtaatta acataattgc
     6061 atcagcacct aaggctttag cttggattga agtttggatt gacttttcag tatcattagt
     6121 gccagttcct gctatgacag gaacacgttt atctacaaga tcaataactg cttttagaat
     6181 gcgttctttt tcatctgttg ttaaagtagg gctctcagca gtagttccat taacgatgat
     6241 tgcttgggca ttattttcta gtaaaaaatt aacgtgtgct ttcaaagctt caagattaac
     6301 tttgttattt gtaaaagggg ttgtaagtgc aacgccaaca ccctcaaata aatgtgtcat
     6361 tttaattcgc tccttttaaa cgcataactt gttccaatac ttgtacagca tttaatgcag
     6421 caccttttaa taaattgtct gatgtacacc atacatggaa agtattttct aatgaatcat
     6481 ctctacgtat acggccaaca aacacttcat ctttattagt agaattgatt gccattggat
     6541 attcattgtt ctctggattg tctactaaaa caacgcggtc atcttgatca aataatgctt
     6601 taatatcttc tgcagtcgct tctttgtcaa gcgttacatc aatttcaaca ctatgactat
     6661 cttgaacagg cacacgtgcg catgttgctg ttacttttaa gtctggcgca tttaaaattt
     6721 ttctcgtctc atcaatcatt ttttgttctt cttttgtata tccattttct aaaaacacat
     6781 caatatgcgg taacacatta ttataaattg gatgtggata tgcttctggt gctttaccat
     6841 ttacaccttc agctaaatct ttcttacctt tcatccctga acctgataca gcttgatatg
     6901 ttgtatatgc cactcgtttt aaaccataag catcttgcaa tacttttaat ggcacaacag
     6961 attgaatcgt agagcagttt ggattggcaa tgatacctct tgtaaatgta ggttcattga
     7021 cttccggaac gattaaatca atatcttctg ccatacgcca ttgacttgaa ttgtctataa
     7081 cgattgcacc agctttttca aagagtgggg caaagtgttc gcttgtaccg ccaccagcac
     7141 tcattaatac ataatcgaaa tgttcacttg cacgagcatc agttaattct tgtactgtat
     7201 atgttttttc ttgaaattca acttcttgcc ctgcagaacg tgctgatgaa aataatacta
     7261 attcatcgaa aggaatattt ttacgattta atgtctccaa catttttgta cctactaatc
     7321 ctgttgcacc cacaactgct aactttgtca taacttgtca ctccatttta taataatttc
     7381 caatttttag aatattttaa caatcatttt accattaaat gttaaatgcg tcatatagtt
     7441 tttctaccgc ttgttgccca ttaaaatcat caatgacgta tgaaatactt atttcagatg
     7501 ttgttgtttg gtagaaaggt atattatttt caattaatgt caaaaatgct tttgatgcca
     7561 cacctgacat atcacgcatg cctgagccaa ttaatgaaat tttgacataa tgctcattga
     7621 ttttataagc taatgcttca tattgattct ttaatgtttc aagaatcata gaaatttgat
     7681 gaaaatcact atctttaatc gtgaaggata gttgtagccc atccaagttg acgatttgtg
     7741 aaatcatatc aacatttaca gcaccttctt caagttccgt aaatagttgg gtaagtagct
     7801 gattgtcagg taggggataa ctaattgtta catgcatcat atgtttatcc aaagccacac
     7861 cagtaactgc ttttttctct aatatttctt catttgacat aatccatgtt cctttcacgt
     7921 tcgataaagt ttttcctaaa tataaaggga tattatagtt tttagctaat tcaacacttc
     7981 ttgtttcaag tacaccagca cctaaagcgc tcatttccat catttcttca tatgagacga
     8041 tgtctagtcg tttagctttt ggtaaaagtc ttgggtcagt ggcatacaca ccatcaacgt
     8101 cggtataaat ttcacaaggt atttgattac taacagcaag tgccacagcg gtcgtatcag
     8161 aaccgcctct gcctaaagtt gttaattcct gatgttcatt gatgccttga aatccagcaa
     8221 ctactaaaat atcgttttct tgaaagactt gttcaaatgt ttgaggatta atttgagcaa
     8281 ttttactttt taaatgatgg ccaatggttt taatacctgc ttgatagcca gtcattgctt
     8341 tggcattcac accgatatca tttaatacca ttgataaata agatacagtt tgttgctctc
     8401 cggttgtcaa taataatgcc agttcttgtt gttttggtgc tttagtcaag gtcgatacat
     8461 tcgtcattaa ttgatctgtt gtgttaccca tagcacttac aacgacaatt aattgttcat
     8521 cttgattgac tcgctccttt aacatttcag cgatcctttt tatttttgta aaatcactga
     8581 cggatgatcc gccaaatttc aacacacttc ttgttaccat ataatcctcc taattgttag
     8641 gaagggcaca caataataaa aaaagagcaa gttcggaatg cgaacttgct cttaatctat
     8701 atacaagtga tgcactccat tatttttaaa taatgacaaa ctctcagctc ttaaccaaaa
     8761 agtccaacaa attataactg ctattataat tgcttcggca tcgcaccctt tcaaatttag
     8821 ctgttagcag acagtaatct aaactttact catgattgat gcgcctcatc aaaatattat
     8881 taaattggta tgtgttcatt atacatatga caaatatgaa tgtaaaccga taatttagat
     8941 tttttggaat aacctgaaaa ttcaagttat agcgttgctt atattttaaa aggtggtgat
     9001 aatgagactt tttgaaaaat aaaattcaaa atacttatag catactcaat atgcacatta
     9061 aataaatgta ctcttttaat gcggtgataa ctgtatttgt aatttagaga aggggtgttc
     9121 actgtgctga tgtgttaaaa aataaaataa aaaggacacc tcgatgctat aaatattagc
     9181 atcgagacgc ccagttaatg tctattaaat tgaatatagt ctcggatatg aatcaatgcc
     9241 ctaggccctg caatgttata ttgacagtag ttgactgaat gaaaatgact ttgtagctag
     9301 cttttttcaa tccttgtcgg tgccacacat agagaaattg gattcctaat ttctacaaac
     9361 aatacaagtt gcggaataag tcccaatata gaaggtgaca gtaagccaac ttacaataat
     9421 gtgcaagttg gtcgggcctc aacacagaga ttttcgaaaa gaaattctac atattatgtt
     9481 tattttaaaa cgccgatttc ttgcaagtat tcttcatatg gaatttcttt tgaaacgccg
     9541 ccttgtttat ttaaatcgat aacacggttt gcaatcgtgt tgataaattc gaagtcataa
     9601 gaagtaaaga tgatagaacc tttaaatgat ttaagaccat cattgacagc agtaatactt
     9661 tctaagtcta agtggttagt aggttcgtca agtaaaagta cattcgcact tgataacatc
     9721 attttactta acatacaacg tactttttct ccacctgaaa gcacactagc ttttttctta
     9781 acttcttcac cactaaataa catacgacct aagaaaccac gtaaaaatgt ttctgtttgt
     9841 tcatcttcag gagcatattg tcttaaccaa tcaacgagat tcatatttac accctcaaag
     9901 aactctgagt tatctttagg gaagtaactt aatgatgtag taacacccca tttaaatgaa
     9961 ccttcgtctg gttccatttc gccagctaat attttaagta atgttgtttt tgcaatttca
    10021 ctatctccaa ttaaaatcgc tttatcattt ggattcattg tgaatgatac attatctaat
    10081 actttttcgc cgtcaattgt tttagaaaga ttttgaacga ttaataagtc gttaccaatc
    10141 tcacgctcag gcgtgaattt aacgaaagga tatcttcttg atgatggttg aatatcatct
    10201 aattcaattt tctcaagttg ttttttacga cttgttgctt gtttagattt agaagcgtta
    10261 gctgagaaac gagcaataaa gtcttgtaac tctttcattt tttcttcttt tttcttgttt
    10321 tgttcttgag ccatcttttg agctaactga ctagattgat accaaaaatc atagttacca
    10381 acataaactt taattttacc aaagtctaaa tcagcgatat gagtacatac attatttaag
    10441 aaatggcggt catgtgatac tacgataaca gtattatcaa agttaattaa gaaatcttct
    10501 aaccaactga ttgctggaat atccagaccg ttagtaggct catccagtaa tagtacgtct
    10561 ggttcaccga ataaactttg cgctaataat actttaattt tttggttgtt ttctaattca
    10621 gccatttttt tatcgtgtaa agttggatcg atacctaaac cagataaaag gttagctgca
    10681 tcagcctcag cattccaacc attcatttct gcaaattcac cttcaagttc agcagcacgg
    10741 ataccatctt catcactgaa atctggcttc atatagattt catctttttc tttcataacc
    10801 tcataaagac gttcgtgacc tttaattaca acatcaagca cacgttcatc ttcataagca
    10861 tagtggtcct gttttaaaac agctagacgt tcatttttac ctaatgaaac atgtcctgtt
    10921 tgagaatcta attcaccaga taatattttt aagaatgttg atttacctgc accattcgca
    10981 ccaattaatc cataacaatt accttctgta aatttaatat ttacatcttc aaatagttta
    11041 cgatctccaa aacgtaaact cacatcagtt acttgtaaca tgcattttct cctttttttc
    11101 attcgatatt ctaacggaag aattatatca tattatcgtc acagtttcga cctcatataa
    11161 gttgtaatga tagaatgact cacacatgtt ataataataa agaatacaag aatcgaagga
    11221 gaataacatg gcattagaca aagatatagt aggttctata gaattccttg aagtagtagg
    11281 gttacaaggt tcaacttacc ttttaaaagg accaaacggt gaaaacgtaa agttaaacca
    11341 atcagaaatg aacgatgatg atgaattaga agtaggtgaa gaatatagtt tcttcattta
    11401 tccaaaccgt tcaggtgaat tatttgcaac tcaaaatatg cctgatatta cgaaagataa
    11461 atatgacttt gctaaagtac ttaaaacgga tcgcgatggg gcacgtatag atgttggatt
    11521 accccgtgaa gtgttagtac catgggaaga tttaccaaaa gtgaaatcac tatggccaca
    11581 actaggtgat catttgctag tcacattacg aattgaccgt gagaatcata tgtatggacg
    11641 attagcgagt gaatctgttg tagaaaatat gtttacacct gtacacgacg ataatttaaa
    11701 aaacgaagtc attgaagcca aaccttaccg cgtattacga attggtagct ttttattaag
    11761 cgaatcaggt tacaaaattt tcgtacatga atcagaacgt aaagctgaac caagattagg
    11821 tgaatctgtt caagttagaa ttatcgggca taatgataaa ggtgagttaa atggttcatt
    11881 tttaccactt gcacatgaac gtttagacga tgacggccaa gtcatctttg atttactagt
    11941 tgaatatgat ggtgaattac cattctggga caaatcaagc cctgaagcga ttaaagaagt
    12001 attcaatatg agtaaaggtt cattcaaacg tgcaatcggt cacttatata aacagaagat
    12061 tattaatata gaaacaggca aaatcacttt aactaaaaaa ggttggagtc gaattgactc
    12121 aaaagaataa tcatttttac acgtatcgta ggatgcgtgt tttttatatt caatattaaa
    12181 tcggatagat gaagtagttt tttaatttca tctgtccatt tttttgtgta catatttaaa
    12241 tttcgataat ttttcaggaa gcattttaat tttactaatg aagcaatatt ttttagatta
    12301 acaaaaatta atatttacat tttcttaaca aatttttatg taacatttac agtttctaaa
    12361 aatgaggtta ataattcaag gttaagataa agatgtaatc aatacaaata ctatttgttg
    12421 ttcatacagg gaggatattt caatgaaaaa atggcaattt gttggtacta cagctttagg
    12481 tgcaacacta ttattaggtg cttgtggtgg cggtaatggt ggcagtggta atagtgattt
    12541 aaaaggggaa gctaaaggtg atggctcatc aacagtagca ccaattgtgg agaaattaaa
    12601 tgaaaaatgg gctcaagatc actcggatgc taaaatctca gcaggacaag ctggtacagg
    12661 tgctggtttc caaaaattca ttgcaggaga tatcgacttc gctgatgctt ctagaccaat
    12721 taaagatgaa gagaagcaaa aattacaaga taagaatatt aaatacaaag aattcaaaat
    12781 tgcgcaagat ggtgtaacgg ttgctgtaaa taaagaaaat gattttgtag atgaattaga
    12841 caaacagcaa ttaaaagcaa tttattctgg aaaagctaaa acatggaaag atgttaatag
    12901 taaatggcca gataaaaaaa taaatgctgt atcaccaaac tcaagtcatg gtacttatga
    12961 cttctttgaa aatgaagtaa tgaataaaga agatattaaa gcagaaaaaa atgctgatac
    13021 aaatgctatc gtttcttctg taacgaaaaa caaagaggga atcggatact ttggatataa
    13081 cttctacgtt caaaataaag ataaattaaa agaagttaaa atcaaagatg aaaatggtaa
    13141 agcaacagag cctacgaaaa aaacaattca agataactct tatgcattaa gtagaccatt
    13201 attcatttat gtaaatgaaa aagcattaaa agataataaa gtaatgtcag aatttatcaa
    13261 attcgtctta gaagataaag gtaaagcagc tgaagaagct ggatatgtag cagcaccaga
    13321 gaaaacatac aaatcacaac tagatgattt aaaagcattt attgataaaa atcaaaaatc
    13381 tgacgacaag aaatctgatg ataaaaagtc tgaagacaaa aaataataag acgcaatttc
    13441 aaatgtgtct tgaaacatga ttttgatggt gaatcattat ttagagtaca aagcttgatt
    13501 tatcgagacg ctgattttga cattcagtaa gtctacaagc ttatcaactt aaaatagtgg
    13561 ttcatcatta ttttacaaat ctaattattt tgggagtaat agaaagaggt ttgattatga
    13621 cttcatctac taatgttaaa gctttaatcg aaaaaaataa taataaaaaa gggaagcata
    13681 atgacaaaat tataccagtt attttagccg caatttcagc gatttccatt ttaacaacac
    13741 taggtatatt aatcacattg cttttagaaa ccatcacttt tttcaccaga attccaataa
    13801 ctgaatttct attttctact acttggaatc ctaccggttc agaccctaag tttggtatct
    13861 gggcattgat aatagggact ttaaaaatca cagttattgc gactatattt gcagttccag
    13921 tcgggcttgg tgcagcaatt tatttaagtg aatatgcaag tgaccgtgca cgacgcataa
    13981 ttaaaccgat attagaaatt ttagcaggaa taccaacaat tgtgtttggt ttctttgcat
    14041 taacctttgt tacaccagta ttaagatctt tcataccagg tcttggagag tttaatgcta
    14101 taagtcccgg cttagttgtc ggtattatga ttgtccctct catcacaagt ttgagtgagg
    14161 atgcaatggc atctgtacca aataaaattc gagaaggtgc ctatggactt ggagcaacta
    14221 aattagaagt agcaactaaa gtcgtacttc ctgcagcaac atcaggtatt gtagcttcaa
    14281 tcgttctcgc gatttcaaga gcaattggag aaacgatgat tgtatcatta gcggcaggta
    14341 gttcgccaac agcttcatta agtttaacaa gttcgattca aacaatgact ggatatattg
    14401 ttgagatagc gacaggtgat gcaacatttg gatcaaatat ttattacagt atttatgctg
    14461 taggattcac attatttatc tttaccttaa tcatgaattt actttctcaa tggatttcta
    14521 agcgttttag ggaggagtat taatatggaa atgacagata ataatagaca atcactcgtc
    14581 gatcaacaac ttgtccaaaa acatttatca tccagaacgg ttaaaaataa agtgttcaaa
    14641 ctcatatttt tagcatgtac attattagga cttgtcgtac ttattgcgtt gttaactcaa
    14701 acattgatta agggggtaag tcatttaaat ttacagtttt tcactaattt ttcttcttca
    14761 acaccatcta tggctggcgt taaaggcgcg ttaatcggtt cactttggtt aatgttaagt
    14821 atcattccat tatcaatcat cctaggaata ggtacagcta tatacttaga agaatatgcg
    14881 aaaaacaaca aatttactca gtttgttaaa atcagtattt ccaatttagc tggtgtacca
    14941 tcagttgtat ttgggttatt aggttacact ttgttcgttg gtggcgcggg gattgaagcc
    15001 ttgaaaatgg gtaacagtat attggcagca gcgctaacaa tgaccttact gatattacca
    15061 attattattg tttcaagtca ggaagcaatt agagctgtac ctaactcagt acgcgaagct
    15121 tcttacggtt taggtgctaa taaatggcaa acgataagac gtgttgtctt accagcagcg
    15181 ttacctggta ttttaactgg attcattttg tctctttcaa gagcactggg agaaacagcg
    15241 ccacttgtgc ttatcggtat accgactata ttattggcaa cacctaggag tatattggat
    15301 caattttcag cattacctat ccaaatattt acttgggcga aaatgcctca agaagaattc
    15361 cagaatgttg catcggcagg cattatcgtt ttactagtta tcttaatatt aatgaatggc
    15421 gttgcgatta ttttacgtaa caaatttagt aaaaaattct aatttaaaca atcaatctca
    15481 tttatctatt aaaaagggag ttttaaacat ggcgcaaaca cttgcacaaa ctaaacaaat
    15541 atctcaaagt catacgtttg atgtctcaca aagtcatcat aaaacaccag atgatacaaa
    15601 ctcacattct gttatatatt caacacaaaa tttagactta tggtatggcg aaaatcatgc
    15661 attgcaaaat attaatttag atatttatga aaatgaaata actgccatta taggtccatc
    15721 tggttgtggc aaatcaacat atattaaaac tttgaatcga atggttgagt tagtacccac
    15781 agtcaaaaca gctggtaaaa tactatatcg cgatcaagac atatttgatc aaaaatattc
    15841 taaagaacaa ttacgtacaa atgtgggcat ggtctttcaa caacctaatc catttccaaa
    15901 atcaatatac gataatatta cttacggtcc aaagattcac ggtattaaaa ataaaaaagt
    15961 tcttgatgaa atcgttgaga aatcattacg tggcgcggca atttgggatg aactaaagga
    16021 taggttgcac acaaatgcat atagtttatc cggcgggcaa caacagcgtg tttgtatcgc
    16081 gcgttgttta gcaattgaac ctgaagtcat tttaatggat gaaccgacat cagcattaga
    16141 cccaatctca acattaagag tagaagagtt ggttcaagaa ctaaaagaaa agtatacaat
    16201 tattatggtt acacataata tgcaacaagc agttcgtgta tcagataaaa ctgcattttt
    16261 cttaaatggt tatgtcaatg aatatgatga tactgataaa attttctcta acccatcaaa
    16321 caagaaaaca gaagattata tttcaggaag gtttggttga tatataatgg caataattag
    16381 acaacgatat caggagcaac ttgatgattt aataaaagaa ttacgtcggt taggtgcaaa
    16441 tgtctatgtg agtattgaaa atggtataaa atcattaagt attgacgata gaggctttgc
    16501 acgacaaaca gttaaaaacg ataaacatat caatcaatta aattataata ttaatgagcg
    16561 agttatcatg ttaattacaa agcaacagcc cattgcgagt gatttgcgta tgatgatttc
    16621 ttcattaaaa atcgcctccg atttagaaag aataggagat aatgcatcga gtattgccaa
    16681 tattcgattg cgtacgaaga ttacagatga ttatgtgtta acccgtttaa agacaatggg
    16741 taaattagct atgttaatgt taaaggactt agatcaagca tttaaaaaga aagataccgt
    16801 attaataaga gaaataattg agcgtgatga agatatcgat gacttatata gtcatattat
    16861 taacgcaacg tatcttattg ataacgatcc atttgtcgct gcacaagctc atttagcagc
    16921 aagacattta gaacgtattg gtgatcatat tattaacatc gctgaaagtg tttattttta
    16981 tttaacaggt acacattacg aacaataact taaagttatt actataaaat cccttacgat
    17041 aaatatatat ttctattatt cataaaccct caaaaaaaaa accaagattc tcacaattag
    17101 taatgtgaaa atcttggttt atattgttct actataaatt gtctcgcatc ttagttattt
    17161 gcttgctcaa tttcatctgt taatttttca acttcatcga ctaaatcaga aatatattga
    17221 attgtagatt taagtggctg ttctgtagta atgtccacac ctgcaatgtt tgcaagttcg
    17281 acaggtgata cactaccacc ttttttcaat gtttctaacc aagcatcaac agcttgttgg
    17341 ccttcatttt taatcttttg agaaacgaca gttccgattg ttaagccagc agaatacgta
    17401 tacgaatata atcccatata gtaatgaggt tgacgcatcc atgttaattc agcaccctca
    17461 gtcatgtcta ctacatctcc aaaaaattgt ttataaacat ttagcattat ttcatttaat
    17521 gtcggcgcat ttaaagattc accttgatct actttgtgat acacttcacg ttgataagca
    17581 gcttctaata aatgggtaac catattatga taatatgttc tagataaaat tgagccaata
    17641 acccaacgct taaatcttgg attatcactt gtgttaaata aataattggc catcaacatt
    17701 tcattcattg tagaaggggc ttcaacaaag tacattgatg cttctgattc aagatatggt
    17761 tgatgttttt gagctgatgt aaaatgacct gcatgaccta attcatgtgc taggacaaat
    17821 gcttcagcca ttttaccagt ccaagaaatg aacacatacg aatgtgtaaa gtatggactt
    17881 gcacaaaatg cgcctgtatc tttaccttta ttttgtgcaa aatcaatcca tcgctgatcg
    17941 tatgcttcac gtaacatgtt tgtatagtca tcacctaaaa cacttaacgc accgaaaata
    18001 taattttttg agtcttcaat tgaaatctct ggttcataat cagggtctac agaaattttc
    18061 aagtcttcaa aacgcatgtt atctaattcg tgaatacgtt gtaaaagttt agcatatttc
    18121 tgcataactg gtgccaagtc acgcataatc atatcgattt gacggtcaaa catatcacgc
    18181 gttacttctt gactatgtag taaataatcg atgaccgatt caaatccacg taaatcagct
    18241 tcaatttttt cttgttgtac ttgcatatta tatgtagccg cggtagtatg ctgatatttt
    18301 cgaatcccat cgctaaacga tttgaaactt ttacgtctaa actcaggatc tttattatct
    18361 tcataatcat tttcaaacgt agcatagtcg acagggtacg ttgtaccatc atgttcaaat
    18421 gaatcgaatg taatatctag catttttgtc gtgccgtata aatcgtaagg actgtttagc
    18481 gtaggtgata aagttgctaa tacttgttct accgacgcag ataattggaa tggcttttgt
    18541 tttattaact gtttaatata gtgttgatat ggacatgatt cttctaattg ttgaagtatt
    18601 tcttctggta attcaagtat ttctgactct acaaatgata attggctaac aattttacca
    18661 tatgtagtag ataatttagc gctcaatact tgcgcctcaa tattactagt atctacactt
    18721 aaacgtagtt ctgcataatt acttaagcga tctaaggcaa ttaaaatatt ttctaattca
    18781 gctaaagcag tattaatttg ttcgattgaa tttaatgttg ttgcatatgt atgatgaaat
    18841 tgatttgctt gttgtactag agcgtcaata ctttcataat attgttgatc atctttaaat
    18901 aagtctacta aatcccatgt ttctgaaaca ggaacatctt ctcttaaaag taaaccttga
    18961 gacatataat cactcctttg gtataataca ttcattatac ataattttgt ctcctaaacg
    19021 ataatgttac gatttccatg tcgcaaggaa caatgatttt tctaatagta gatagaatat
    19081 tgcttgaaac tgactgctat tgtttaagtt tttaaaaatt tataataaaa tgtatacaag
    19141 gaaagtaatg aaataaaagg agaatgaata tgacattatt cgatatgcct aattatttat
    19201 ggattacaac attaataatg attttattaa caatattctg ttgcttagtt ttaaataaat
    19261 ggtttgtatc tgcagtaatt acatttgtta tattaggtgt gcttgcattt tttattccaa
    19321 attttcaaga tataaaatat caaccattat taggatacgc tgcattttta gcgattatga
    19381 gtttattaat tagttttcta ttatggtatt ttactagaaa ttggcgtaaa gaaagaaaag
    19441 cgcgtaaatt agaaaagcaa attgaaaaat acggctatga gggcgctgaa cttcgccgta
    19501 aagataaaaa ataatattcg acaactatat gcacaaaatc atcgactttt aagttacact
    19561 gcagtaacaa ttatttcgaa agagatggaa tacagtgcta tagttgtttt tgttttgact
    19621 tttttatatt ttacatggtt gacttgattc aaaatattat attttataat gattttgtta
    19681 aaaaattaaa tatacttcaa tttcttttgg gataatacta taatgaacgt tggttcttaa
    19741 tatgtaagtt gcatatacac gcgccattct catgtaacaa gaaagtgttg gtaacttaca
    19801 caaggagggg gactattatg ttcataataa agtctatgat gtatagactg atacaaatga
    19861 tagttgtttt atttgttatt tctacactta cattcatttt aatgaaatta tcaccaggaa
    19921 atcctgttga taaaatatta catcttgatg tagcacaagt gtcgacggaa caaataaatg
    19981 caaccaaaga taaattggga ttaaatgatt ctttattggt acagtggtgg cattggatga
    20041 atcatttatt acattttaat ttaggaaaaa gttttgaatc aaaagaaccg gtaacacaga
    20101 tattattcaa ctatgcaccc ataacattac tcatatcatt ttcaacatta gtagtgtcgt
    20161 tatgcatatc tataccgctc ggcattatag cagccaaacg atttcataag tggacggata
    20221 aagtgattag agtgatctca acactatcaa ttagtttacc agcgttcttt atcggtatta
    20281 ttttattatt tattgtcaca aatttaatga atatagatag cgttatacta agtcagttta
    20341 tattacctgt actcacacta tctttaggta tgtgtgcata catcattcgt tttgtgcgct
    20401 ctaatttatt gatgttattg caaagtaata tcgtacaagc atcaagatta cgcggtatga
    20461 atgaacgtta tattttaatt catgatttac taaaaccaac aatttttccg attatcccat
    20521 tattagggat ttcacttggt agtctaatag gtggtactgt agtgattgaa aatttatttg
    20581 atatacctgg tattggttat ctattaatgg atagtattaa atctcgagat tatcctgtta
    20641 ttcaaggatg cgtgttattt attggcttct tcgttgttat tattaatacg attgctgatt
    20701 tattaacgtt attacttgat ccgaagcagc gtctacaatt aggaaatcca aaaaacaaaa
    20761 ccaatacacc attgatatca gaaggtagtg accgtcatgc ataaaatatt ttcaaagaat
    20821 aacctgatat tttttgtatt cgttgcattt atttttgtgg taattgtact gcaattcttt
    20881 gtaagtagtg aaaatacaac caaagtcaat ttatcacaaa cttttgaacc tattagttgg
    20941 ttgcatttat taggaactga tgattatggg agagatttat ttacccgaat tattatcggt
    21001 gcacgttcaa cattgtttgt tactgtttta acattaatag ctatcgttgt cataggtgtt
    21061 acactaggtc tatttgccgg atataaaaag gggtggattg aacgattagt gttaaggttt
    21121 attgatgttg gtctaagtat tccagaattt atcatcatga ttgctttagc aagctttttc
    21181 caaccatcgt tatggaattt agttatttca attgcagtaa taaaatggat gaattacaca
    21241 aggttgacta gaagtatagt taatagcgaa atgaataagc cttatataaa aatggcacaa
    21301 ttatttcatg tacctacaag aacaatatta atacgtcatt taacacctaa aattataccg
    21361 gctattatcg ttttgatggt cgttgatttc ggtaaaatca ttctatatat aagttcacta
    21421 tcatttattg ggttaggtgc acaaccgcca acaccagagt ggggcgctat gttgcaacaa
    21481 ggtcgtgatt ttatttcgtc tcatccaatt atgttgattg cacctgcttc agtcattgct
    21541 ataactattt taatttttaa tttaaccggt gatacgctaa gagatagatt gctgaaacaa
    21601 cgaggtgaat atgatgagtc tcattgatat acaaaattta acaataaaga atactagtga
    21661 gaaatcactt attaaaggga ttgatttgaa aatttttagt caacggatta atgccttgat
    21721 tggagagagc ggcgctggaa aaagtttgat tgctaaagcc ttacttgaat atttaccatt
    21781 cgatttaacc tgcacgtatg attcgtacca atttgatggg gaaaatgtta gtaaattgag
    21841 tcaatattat ggtcatacaa ttggctatat ttctcaaaat tatgcagaaa gttttaacga
    21901 ccatactaaa ttaggtaaac agttaactgc gatttatcgt aagcattata aaaatagtaa
    21961 agaagaggct ttgtccaaaa ttgataaggc tttgtcgtgg gttaatttac aaagcaaaga
    22021 tatattaaat aaatatagtt tccaactttc tgggggccaa cttgaacgcg tatacatagc
    22081 aagcgttctc atgttggagc ctaaattaat cattgcagac gaaccagttg catcattgga
    22141 tgctttgaac ggtaatcaag tgatggattt attacagcat attgtattag aacatggtca
    22201 aacattattt attatcacac ataacttaag tcatgtattg aaatattgtc agtacattaa
    22261 tgttttaaaa gaaggtcaaa tcattgaacg aggtaatatt aatcatttca agtatgagca
    22321 tttgcatccg tatactgaac gtctaattaa atatagaaca caattaaaga gggattacta
    22381 tgattgagtt aaaacatgtg acttttggtt ataataaaaa gcagatggtg ctacaagata
    22441 tcaatattac tatacctgat ggagaaaatg ttggtatttt aggcgaaagt ggctgtggta
    22501 aaagtacgct cgcttcattg gttcttggct tgtttaaacc tgttaaagga gaaatttact
    22561 taagtgataa tgctgtgtta ccgattttcc aacacccttt aactagcttt aaccctgatt
    22621 ggacggacga ttgagacctc attaaaagaa gcgttatatt attacagagg cctaactgat
    22681 aatactgctc aggatcaatt attaatacaa catttatcta cttttgagtt gaacgcgcaa
    22741 ttattgacta aattaccaag cgaagtgagt ggtggacaat tacaaagatt taatgtcatg
    22801 cgttcgttat tagtacaacc tcgcgtttta atatgtgatg agataacttc aaatttagat
    22861 gttatagctg aacaaaatgt aataaatata ttaaaagcgc aaacgattac gaacttaaat
    22921 cattttatcg ttatttctca tgatttatcc gtgttacaac gcttagttaa tagaattatc
    22981 gttcttaagg atggcatgat agtcgatgat tttgcaatag aggaattatt taatgttgat
    23041 agacaccctt atacaaaaga attagtgcaa gcattttcat attagttatt taagaatgcg
    23101 ataattctag acttgttata aaatatagat aaatcaagta tattaatcta gacacttatc
    23161 gattttattt tctgtattta aaaataataa taaaaaggag tatcattaat gggattactt
    23221 gatattgcaa gtattcgttc tatagaaaga ggctttaatt attatcaaag tgaatgcgtc
    23281 attaacttaa aatcattttc agaaacgcag catgaggctg aagtaaaagg cagtggtaac
    23341 aaagtatatc gttgttatat tgatatggaa catcctagaa aatccaaatg taattgtcct
    23401 catgctgatg gaagacgagt gatatgtaaa catatgattg cattactctt tacagctagt
    23461 ccagaagcag caaataaaca tataatcatg ttaaacgaag ttgaagaaga ctatcactta
    23521 cgcagaaata tgtggattga ttctcttaaa gaaatgatta atgatatgag tgaagaagaa
    23581 ctccgcgatg catatttaaa catgttaatt gaacatggag aaatggcaga attatttgga
    23641 ttagatgaag aggacgaaat gttcgaggac gaattttatt aaaatagccc ctatcgattg
    23701 ataatgatta tcatttgata ggggtgtttt ttatttatat gattttaaga ctttgcaaat
    23761 agcttgtgca ttattattga tgtgtttgat tttatcaagt ttcaatattg cgtgtgtgta
    23821 tgcttctgat ggtcctataa tatagccact actagcatgt tgtaacatga caatatcatt
    23881 gtggtcatta ccaaatgcta tatatttaac atctgcatca aatatatatt gtaatgcagt
    23941 atatttatta atattttgcg ctgttatatc aatgttatac tcatttgaat ggtgaatcat
    24001 ttccaattct tgatggtatt tatttagctc gtctaatata gttgtaattt gtgccgggtc
    24061 tatatttaat aaaataactt tgattggcgt gtcgatattt gcaacatcaa tacaactggc
    24121 cagcttatgt ggatctaaac gctcaaaaat cgcgttctca gcgtcaagtt gtgcagcata
    24181 attccaatca tcatcaataa taaaatctaa ctcatacttt tgaattattt ttaagatatg
    24241 gtgatatgta tcagtatgaa ttggtttgat aacagaaatc tttgattgct gtgaaatcat
    24301 agcaccattt gcgccaatta atgtgtgccg atgaaatact gatggtaaaa ctggcaacaa
    24361 atcacgaatt ggacgtgctg atgcaaatat aagttcatga ccatcatgtt gtaattgtaa
    24421 caatgtatca ataatagtct gatcaattaa tcggccgtca aaacaaagcg taccatcaat
    24481 atcaaagaca aatctcatca aatcactcca aacaatataa taccatgatt atagcataag
    24541 taagttgatt atagcataag taagttatgt gacgatatta gataatgatt atgatgtagg
    24601 gtaccttttg cgtcacacac attacttcct ataatatata ttatgtaaac tagaatgtga
    24661 aattccataa ggggacttat ataactgtat gtttgtgtaa ctcgttttga ttattagtaa
    24721 agtatgtttg tagttactat taacttttta tttaacacat gctattttat caatacttct
    24781 attattagga ttagtacata aataaactaa aattaacgcg acaaaattta gaaaatctat
    24841 aaaaacaaat aagatttgtg cagattgagt ttgatatatg accaaaagta ttgaaagtaa
    24901 aaatagtaga attaatatta attttaaaca agatataatt aatggtaaac atctgacaac
    24961 tggttttctt tcttttaata aagaacacga aaataataac cacattatta tgcaaaagtt
    25021 acacactaga tatgtactaa aagaaatacc accttcttgt atgacatatc taaataagtt
    25081 cacagcaaat tcatgattat tatgaatatt tgccttacta attaaactaa ttgtaaattc
    25141 tgcagtgtat ccttgaataa tcaatgaaat tccattaact aaaaagtata ataataggaa
    25201 taacgtactt ataatattat tatagttatt atcttttttg atgtcattga atctaaaaaa
    25261 gaaattgagt ggaattaaca cacaggcaat gtatgctatt ccttttgata tatgatccaa
    25321 accgtaatat ccctttaaat gtgtataata tttcaatgct tcatatgtag ttaaattatt
    25381 tttcgaaggt ggaaataata atttctggaa aataaaactc ataaaaatcc aaaataacat
    25441 aatgagcatc agaataataa aagtgttttt agcatgtttt tcaattcgat tcattttttt
    25501 aactacctca cttacttgca tttc
//
LOCUS       DAPSKH010000042        23811 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPSKH010000042 DAPSKH010000000
VERSION     DAPSKH010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 23811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23811
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.042"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(140..553)
                     /locus_tag="RPH49_001779"
     CDS             complement(140..553)
                     /locus_tag="RPH49_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124920.1"
                     /translation="MKPTKVILRDASYLHSKTSITFILKDVVIEEDNKIYYFDTSATF
                     EDQEVKFEFALFDSDMDNLKHMDYDNPVTEIYFIEPDLHFTIIDFNQELLCIYIDFDS
                     GLRHSNMATESGISLRINVAKSDFTKFINELASLH"
     gene            complement(582..692)
                     /locus_tag="RPH49_001780"
     CDS             complement(582..692)
                     /locus_tag="RPH49_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124921.1"
                     /translation="MDGNNQIDVCFFVLVNNYYTMSIYPRIINSNGDYAT"
     gene            complement(778..1509)
                     /locus_tag="RPH49_001781"
     CDS             complement(778..1509)
                     /locus_tag="RPH49_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDY5124922.1"
                     /translation="MHELTIYHFMSDKLNLYSDIGNIIALRQRAKKRNIKVNVVEINE
                     TEGITFDECDIFFIGGGSDREQALATKELSKIKTPLKEAIEDGMPGLTICGGYQFLGK
                     KYITPDGTELEGLGILDFYTESKTNRLTGDIVIESDTFGTIVGFENHGGRTYHDFGTL
                     GHVTFGYGNNDEDKKEGIHYKNLLGTYLHGPILPKNYEITDYLLEKACERKGIPFEPK
                     EIDNEAEIQAKQVLIDRANRQKKSR"
     gene            complement(1511..2824)
                     /gene="murT"
                     /locus_tag="RPH49_001782"
     CDS             complement(1511..2824)
                     /gene="murT"
                     /locus_tag="RPH49_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid II isoglutaminyl synthase subunit MurT"
                     /protein_id="HDY5124923.1"
                     /translation="MRQWTAIHLAKLARKASRAVGKRGTDLPGQIARKVDTDILRKLA
                     EQVDDIVFISGTNGKTTTSNLIGHTLKANNIQIIHNNEGANMAAGITSAFIMQSTPKT
                     KIAVIEIDEGSIPRVLKEVTPSMMVFTNFFRDQMDRFGEIDIMVNNIAETISNKGIKL
                     LLNADDPFVSRLKIASDTIVYYGMKAHAHEFEQSTMNESRYCPNCGRLLQYDYIHYNQ
                     IGHYHCQCGFKREQAKYEISSFDVAPFLHLNINDEKYDMKIAGDFNAYNALAAYSVLR
                     ELGLNEQTIKNGFETYTSDNGRMQYFKKERKEAMINLAKNPAGMNASLSVGEQLEGEK
                     VYVISLNDNAADGRDTSWIYDADFEKLSKQQIEAIIVTGTRAEELQLRLKLAEVEVPI
                     IVERDIYKATAKTMDYKGFTVAIPNYTSLAPMLEQLNRSFEGGQS"
     gene            3116..3616
                     /gene="ftnA"
                     /locus_tag="RPH49_001783"
     CDS             3116..3616
                     /gene="ftnA"
                     /locus_tag="RPH49_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-type ferritin FtnA"
                     /protein_id="HDY5124924.1"
                     /translation="MLSKNLLEALNDQMNHEYFAAHAYMAMAAYCDKESYEGFANFFI
                     QQAKEERFHGQKIYNYINDRGAHAEFRAVSAPKIDFSSILETFKDSLSQEQEVTRRFY
                     NLSEIARQDKDYATISFLNWFLDEQVEEESMFETHINYLTRIGDDSNALYLYEKELGA
                     RTFDEE"
     gene            complement(3698..3790)
                     /locus_tag="RPH49_001784"
     CDS             complement(3698..3790)
                     /locus_tag="RPH49_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124925.1"
                     /translation="MTKNTIISLENEKTQINDSENESSDLRKAK"
     gene            4006..4560
                     /locus_tag="RPH49_001785"
     CDS             4006..4560
                     /locus_tag="RPH49_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HDY5124926.1"
                     /translation="MIQDAFVALDFETANGKRTSICSVGMVKVIDSQITETFHTLVNP
                     QDYFSQQNIKVHGIQPEDVENAPTFDYVFPYMMQFIADLPVVAHNAAFDMNVLHQSIQ
                     NIGLPTPNLTYFCSYQLAKRTVDSYRYGLKHMMEFYQLDFHGHHDALNDAKACAMITF
                     RLLKNYENLTYVTNIYGKNLKDKG"
     gene            complement(4628..5698)
                     /gene="dinB"
                     /locus_tag="RPH49_001786"
     CDS             complement(4628..5698)
                     /gene="dinB"
                     /locus_tag="RPH49_001786"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011302771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDY5124927.1"
                     /translation="MTERRIIHIDMDYFFAQVEMRDNPKLKGKPVIVGGKASSRGVVS
                     TASYEARKYGVHSAMPMSQAHKLCPNGYFVTSNFGAYRETSAQIMSIFRSYTDKVEPM
                     SLDEAYLDITELVRPDLPASKIAQYIRKDILEQTHLTASAGVSYNKFLAKLASGMNKP
                     DGLTVIDYQNVHDILMTLDIGDFPGVGKASKKVMHDNGIFNGRDLYEKTEFELIRLFG
                     KRGRGLYNKARGIDHSEVKSSRVRKSVGTERTFATDVNDDEEILRKVWELSGKTAERL
                     NKLQKSAKTVTVKIKTYQFETLSKQMSLRDSVSSEEDIYNIAYLLYNDLKDPDVPIRL
                     IGVTVGNLEQSTYKNMTIYDFI"
     gene            complement(5945..6475)
                     /locus_tag="RPH49_001787"
     CDS             complement(5945..6475)
                     /locus_tag="RPH49_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HDY5124928.1"
                     /translation="MHKIDLTTNNFQMRRFIILQLVIALFVILFTYKWALGVTAVVDQ
                     NIIINLVYGFAGFIILLILHELIHRALFLLFKKDSKPMFNIKKDRILFQTADACFNKW
                     QFSIIMLSPLFLLSTGLLILIKVFGYSSLIFMFSMHTAYCFIDILLVALTISSSFKYV
                     QQDEDSIYLYHQKPTQ"
     gene            complement(6645..8006)
                     /gene="rlmD"
                     /locus_tag="RPH49_001788"
     CDS             complement(6645..8006)
                     /gene="rlmD"
                     /locus_tag="RPH49_001788"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDY5124929.1"
                     /translation="MQAIAKNDIKMGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIE
                     YKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVI
                     NLFQRKAHFDNSKFNDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
                     SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTN
                     GKKWPQKNAVVEKILDAFPNVTSIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDST
                     FKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYG
                     VEVVPSAIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDE
                     TFIQTLLTLEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALF
                     NLK"
     gene            complement(8087..9034)
                     /locus_tag="RPH49_001789"
     CDS             complement(8087..9034)
                     /locus_tag="RPH49_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDY5124930.1"
                     /translation="MRKRARIIYNPTSGKELFKRELPDALIKLEKAGYETSAYATEKI
                     GDATLEAERAMHENYDVLIAAGGDGTLNEVVNGIAEKPNRPKLGVIPMGTVNDFGRAL
                     HIPNDIMGALDVIIEGHSTKVDIGKMNNRYFINLAAGGQLTQVSYETPSKLKSIVGPF
                     AYYIKGFEMLPQMKAVDLRIEYDGNVFQGEALLFFLGLTNSMAGFEKLVPDAKLDDGY
                     FTLIIVEKSNLAELGHIMTLASRGEHTKHPKVIYEKAKAINISSFTDLQLNVDGEYGG
                     KLPANFLNLERHIDVFAPNDIVNEELINNDHVDDNLIEE"
     gene            complement(9727..9873)
                     /locus_tag="RPH49_001790"
     CDS             complement(9727..9873)
                     /locus_tag="RPH49_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124931.1"
                     /translation="MIADLDAIEGLFISIEVILLLTLFIVHVNGKNINFINALALIIL
                     RQTV"
     gene            complement(9913..11340)
                     /gene="gatB"
                     /locus_tag="RPH49_001791"
     CDS             complement(9913..11340)
                     /gene="gatB"
                     /locus_tag="RPH49_001791"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDY5124932.1"
                     /translation="MHFETVIGLEVHVELKTDSKMFSPSPAHFGAEPNSNTNVIDLAY
                     PGVLPVVNKRAVDWAMRAAMALNMEIATESKFDRKNYFYPDNPKAYQISQFDQPIGEN
                     GYIDIEVDGETKRIGITRLHMEEDAGKSTHKGEYSLVDLNRQGTPLIEIVSEPDIRSP
                     KEAYAYLEKLRSIIQYTGVSDVKMEEGSLRCDANISLRPYGQEKFGTKAELKNLNSFN
                     YVRKGLEYEEKRQEEELLNGGEIGQETRRFDESTGKTILMRVKEGSDDYRYFPEPDIV
                     PLYIDDAWKERVRQTIPELPDERKAKYVNELGLPAYDAHVLTLTKEMSDFFESTIEHG
                     ADVKLTSNWLMGGVNEYLNKNQVELLDTKLTPENLAGMIKLIEDGTMSSKIAKKVFPE
                     LAAKGGNAKQIMEDNGLVQISDEATLLKFVNEALDNNEQSVEDYKNGKGKAMGFLVGQ
                     IMKASKGQANPQLVNQLLKQELDKR"
     gene            complement(11353..12810)
                     /gene="gatA"
                     /locus_tag="RPH49_001792"
     CDS             complement(11353..12810)
                     /gene="gatA"
                     /locus_tag="RPH49_001792"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDY5124933.1"
                     /translation="MSIRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFL
                     ALDKENAIKKAQELDELQAKDQMDGKLFGIPMGIKDNIITNGLETTCASKMLEGFVPI
                     YESTVMEKLHNENAVLIGKLNMDEFAMGGSTETSYFKKTVNPFDHKAVPGGSSGGSAA
                     AVAAGLVPFSLGSDTGGSIRQPAAYCGVVGMKPTYGRVSRFGLVAFASSLDQIGPLTR
                     NVKDNAIVLEAISGADANDSTSAPVDDVDFTSEIGKDIKGLKVALPKEYLGEGVADDV
                     KEAVQNAVETLKSLGAVVEEVSLPNTKFGIPSYYVIASSEASSNLSRFDGIRYGYHSK
                     EAHSLEELYKMSRSEGFGKEVKRRIFLGTFALSSGYYDAYYKKSQKVRTLIKNDFDKV
                     FENYDVVVGPTAPTTAFNLGEEIDDPLTMYANDLLTTPVNLAGLPGISVPCGQSNGRP
                     IGLQFIGKPFDEKTLYRVAYQYETQYNLHDVYEKL"
     gene            complement(12812..13114)
                     /gene="gatC"
                     /locus_tag="RPH49_001793"
     CDS             complement(12812..13114)
                     /gene="gatC"
                     /locus_tag="RPH49_001793"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDY5124934.1"
                     /translation="MTKVTREEVEHIANLARLQISPEETEEMANTLESILDFAKQNDS
                     ADTEGVEPTYHVLDLQNVLREDKAIKGIPQELALKNAKETEDGQFKVPTIMNEEDA"
     gene            13480..15018
                     /gene="putP"
                     /locus_tag="RPH49_001794"
     CDS             13480..15018
                     /gene="putP"
                     /locus_tag="RPH49_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDY5124935.1"
                     /translation="MLTMGTALSQQVDANWQTYIMIAVYFLILIVIGFYGYKQATGNL
                     SEYMLGGRSIGPYITALSAGASDMSGWMIMGLPGSVYSTGLSAMWITIGLTLGAYINY
                     FVVAPRLRVYTELAGDAITLPDFFKNRLNDKNNVLKIISGLIIVIFFTLYTHSGFVSG
                     GKLFESAFGLDYHFGLILVAFIVIFYTFFGGYLAVSITDFFQGVIMLIAMVMVPIVAM
                     MNLNGWGTFHDVAAMKPTNLNLFKGLSFIGIISLFSWGLGYFGQPHIIVRFMSIKSHK
                     MLPKARRLGISWMAVGLLGAVAVGLTGIAFVPAYHIKLEDPETLFIVMSQVLFHPLVG
                     GFLLAAILAAIMSTISSQLLVTSSSLTEDFYKLIRGEEKAKTHQKEFVMIGRLSVLAV
                     AIVAIAIAWNPNDTILNLVGNAWAGFGASFSPLVLFALYWKGLTRAGAVSGMVSGALV
                     VIVWIAWIKPLAHINEIFGLYEIIPGFIVSVIVTYVVSKLTKKPGAFVETDLNKVRDI
                     VREK"
     gene            complement(15107..16306)
                     /locus_tag="RPH49_001795"
     CDS             complement(15107..16306)
                     /locus_tag="RPH49_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CamS family sex pheromone protein"
                     /protein_id="HDY5124936.1"
                     /translation="MKRTLVLLITAIFILAACGNHKDDQAGKDNQKHNNSSNQVKEIA
                     TDKNVQGDNYRTLLPFKESQARGLLQDNMANSYNGGDFEDGLLNLSKEVFPTDKYLYQ
                     DGQFLDKKTINAYLNPKYTKREIDKMSEKDKKDKKANENLGLNPSHEGETDPEKIAEK
                     SPAYLSNILEQDFYGGGDTKGKNIKGMTIGLAMNSVYYYKKEKDGPTFSKKLDDSEVK
                     KQGKQMASEILSRLRENDDLKDIPIHFAIYKQSSEDSITPGEFITQATAEKSQTKLNE
                     WHNINEKSALLPSSTAADYDENLNNNFKQFNDNLQSYFSNFTQAVGKVKFVDKKPQRL
                     VVDLPIDYYGQAETIGITQYVTEQANKYFDKIDNYEIRIKDGNQPRALISKTKDDKEP
                     QVHIYSN"
     gene            complement(16319..18322)
                     /gene="ligA"
                     /locus_tag="RPH49_001796"
     CDS             complement(16319..18322)
                     /gene="ligA"
                     /locus_tag="RPH49_001796"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDY5124937.1"
                     /translation="MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIK
                     IEEEHPEYKTVDSPTVRVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQI
                     GNVEYMCELKIDGLAVSLKYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPL
                     NVEVRGEAYMPRRSFLRLNEEKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFI
                     YSVNDFTDFNARSQSEALDELDKLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYD
                     IDGIVIKVNDLDQQDEMGFTQKSPRWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTA
                     ILEPVKVAGTTVSRASLHNEDLIHDRDIRIGDSVVVKKAGDIIPEVVRSIPERRPEDA
                     VTYHMPTHCPSCGHELVRIEGEVALRCINPKCQAQLVEGLIHFVSRQAMNIDGLGTKI
                     IQQLYQSELIKDVADIFYLTEEDLLPLDRMGQKKVDNLLAAIQQAKDNSLENLLFGLG
                     IRHLGVKASQVLAEKYETIDRLLTVTEAELVEIHDIGDKVAQSVVTYLENEDIRALIQ
                     KLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTGKLHQMTRNEASKWLASQGAKVTSS
                     VTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVDKQNELNS"
     gene            complement(18326..20518)
                     /gene="pcrA"
                     /locus_tag="RPH49_001797"
     CDS             complement(18326..20518)
                     /gene="pcrA"
                     /locus_tag="RPH49_001797"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDY5124938.1"
                     /translation="MNALLNHMNTEQSEAVKTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     LDEKDVSPYNVLAITFTNKAAREMKERVQKLVGDQAEVIWMSTFHSMCVRILRRDADR
                     IGIERNFTIIDPTDQKSVIKDVLKNENIDSKKFEPRMFIGAISNLKNELKTPADAQKE
                     ATDYHSQMVATVYSGYQRQLSRNEALDFDDLIMTTINLFERVPEVLEYYQNKFQYIHV
                     DEYQDTNKAQYTLVKLLASKFKNLCVVGDSDQSIYGWRGADIQNILSFEKDYPEANTI
                     FLEQNYRSTKTILNAANEVIKNNSERKPKGLWTANTNGEKIHYYEAMTERDEAEFVIR
                     EIMKHQRNGKKYQDMAILYRTNAQSRVLEETFMKSNMPYTMVGGQKFYDRKEIKDLLS
                     YLRIIANSNDDISLQRIINVPKRGVGPSSVEKVQNYALQNNISMFDALGEADFIGLSK
                     KVTQECLNFYELIQSLIKEQEFLEIHEIVDEVLQKSGYREMLERENTLESRSRLENID
                     EFMSVPKDYEENTPLEEQSLINFLTDLSLVADIDEADTENGVTLMTMHSAKGLEFPIV
                     FIMGMEESLFPHIRAIKSEDDHEMQEERRICYVAITRAEEVLYITHATSRMLFGRPQS
                     NMPSRFLKEIPESLLENHSSGKRQTIQPKAKPFAKRGFSQRTTSTKKQVSSSDWNVGD
                     KVMHKAWGEGMVSNVNEKNGSIELDIIFKSQGPKRLLAQFAPIEKKED"
     gene            complement(20515..21207)
                     /locus_tag="RPH49_001798"
     CDS             complement(20515..21207)
                     /locus_tag="RPH49_001798"
                     /EC_number="2.5.1.n9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heptaprenylglyceryl phosphate synthase"
                     /protein_id="HDY5124939.1"
                     /translation="MYDIKKWRHIFKLDPAKHISDDDLDAICMSQTDAIMIGGTDDVT
                     EDNVIHLMSRVRRYPLPLVLEISNIESVMPGFDFYFVPTVLNSTDVAFHNGILLEALK
                     TYGHSIDFEEVIFEGYVVCNADSKVAKHTKANTDLTTEDLEAYAQMVNHMYRLPVMYI
                     EYSGIYGDVSKVQAVSEHLTETQLFYGGGISSEQQATEMAAIADTIIVGDIIYKDIKK
                     ALKTVKIKESSK"
     gene            complement(21379..21681)
                     /locus_tag="RPH49_001799"
     CDS             complement(21379..21681)
                     /locus_tag="RPH49_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124940.1"
                     /translation="MQIEKLRGAALDELFDAILTLENREECYQFFDDLCTVNEIQSLS
                     QRLQVAKMIKQGYTYATIEQESGASTATISRVKRSLQWGNDAYTMILDRMNIETNE"
     gene            complement(21790..23085)
                     /gene="purB"
                     /locus_tag="RPH49_001800"
     CDS             complement(21790..23085)
                     /gene="purB"
                     /locus_tag="RPH49_001800"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDY5124941.1"
                     /translation="MIERYSREEMSDIWTDQNRYEAWLEVEILACEAWSELGHIPKAD
                     VQKIRQNAKVNVERAQEIEQETRHDVVAFTRQVSETLGEERKWVHYGLTSTDVVDTAL
                     SFVIKQANDIIEKDLERFIDVLAEKAKNYKYTLMMGRTHGVHAEPTTFGVKMALWYTE
                     MQRNLQRFKQVREEIEVGKMSGAVGTFANIPPEIESYVCKHLGIGTAPVSTQTLQRDR
                     HAYYIATLALIATSLEKFAVEIRNLQKTETREVEEAFAKGQKGSSAMPHKRNPIGSEN
                     ITGISRVIRGYITTAYENVPLWHERDISHSSAERIMLPDVTIALDYALNRFTNIVDRL
                     TVFEDNMRNNIDKTFGLIFSQRVLLALINKGMVREEAYDKVQPKAMISWETKTPFREL
                     IEQDESITSVLTKEELDECFDPKHHLNQVDTIFKRAGLA"
BASE COUNT         7245 a         4390 c         3378 g         8798 t
ORIGIN      
        1 gcctcttttt atcgtatata gcatgtccct ttttaaaatt acaagcataa atattcagac
       61 tcaaatatag ccacacgcct aaactacgga gggatgtggc tgtctttttt gattgtaatt
      121 atgtatcaga tttaaatcat taatgtaaag aggctaattc attaataaat ttagtaaaat
      181 ctgatttagc aacatttatc cttaatgaaa taccagattc tgttgccatg tttgaatgcc
      241 ttaaaccaga atcaaaatca atataaatac aaagcagttc ttgattaaaa tcaataatcg
      301 taaaatgtaa atcaggttct ataaaatata tttcggtaac aggattgtcg taatccatat
      361 gtttcaaatt gtccatgtca ctatcaaaaa gtgcaaattc aaatttaact tcttgatctt
      421 cgaaagttgc actagtgtcg aaataataaa ttttattatc ttcttcgata actacatctt
      481 ttaaaataaa tgttatcgat gttttgctat gtaaataaga tgcatctctt aaaatcactt
      541 tagtgggctt catcgtcaaa ttcctttcat cattcatttt ttcatgttgc ataatcacca
      601 ttactattga taattctagg atagatactc attgtataat aattattcac tagaacaaaa
      661 aaacacacat caatttggtt gtttccatcc aaaataatgt gtgtgtttat acatatatga
      721 ttaattacta aacttcatcg tttatcaata ttaaatccat tgatgcgata ttcagagtta
      781 acgagatttc ttctgtctat ttgctctgtc tattaatact tgtttcgctt gtatttccgc
      841 ttcattatct atttctttag gctcaaacgg aataccctta cgttcacaag ctttttctaa
      901 cagataatca gtgatttcgt aatttttagg taaaattggt ccgtgtaaat aagtacctaa
      961 taaattttta taatgaatgc cttctttttt atcttcatca ttattaccat aaccaaaagt
     1021 aacatgacca agtgtaccga aatcatgata tgttctacca ccgtgatttt caaaacctac
     1081 aatagttcca aaagtatcac tttcgataac aatatctcct gttaatcggt ttgtctttga
     1141 ttcagtataa aaatctaaaa tacctaaccc ttctaattct gtaccatcag gcgtgatata
     1201 tttttttcct aaaaattgat agcctccaca aattgttaat cccggcatac catcttcaat
     1261 cgcttcttta agtggtgtct taattttact taattctttt gttgctaatg cttgttctct
     1321 atcacttcca ccaccgataa agaaaatatc acattcatca aaggtaatac cttctgtttc
     1381 attgatttct acgacattaa ctttaatatt tcgtttttta gcacgttgtc ttaaagcaat
     1441 aatatttcct atatcactgt ataaattcaa tttatctgac ataaaatgat aaatagtcaa
     1501 ttcatgcata ttatgattga cctccttcaa acgaacggtt taattgttca agcataggcg
     1561 ctaatgatgt atagtttggt attgcaactg tgaaaccttt ataatccata gtctttgccg
     1621 ttgctttata aatatcacgc tcaactataa ttggtacttc aacctctgct aacttcaatc
     1681 gcaattgaag ttcttctgct cgtgtacctg tcacgatgat agcttcaatt tgttgcttag
     1741 ataatttttc aaaatctgca tcataaatcc atgaagtatc tcgaccatct gcagcgttat
     1801 catttagcga aataacatac actttttcgc cttctaattg ttcaccaact gataaacttg
     1861 cattcattcc tgcagggttt ttagctaaat tgatcatcgc ttcttttcgt tcttttttaa
     1921 agtactgcat acgaccattg tctgatgtat acgtttcaaa gccattttta attgtttgtt
     1981 catttaaccc aagctctctt aaaactgaat atgctgctaa cgcgttataa gcgttaaagt
     2041 cacctgcaat tttcatatca tatttttcat cattgatatt taaatgtaaa aacggtgcca
     2101 catcaaaact tgatatttca tattttgctt gctctcgttt gaaaccacac tgacagtgat
     2161 aatgaccaat ttgattataa tgaatataat cgtattgcaa taagcgacca cagtttggac
     2221 aatatctact ttcattcatc gtactttgtt caaattcatg ggcatgtgct ttcataccat
     2281 agtacacaat cgtatcactt gcgattttca aacgactcac aaatggatca tcagcattta
     2341 gcaataattt gatgccttta ttactaattg tctctgcaat gttattaacc ataatatcaa
     2401 tttcaccgaa gcgatccatt tgatctctaa agaaattagt aaataccatc attgaaggtg
     2461 taacttcttt taacacacgt ggaatcgaac cttcatcaat ttcgattacc gcaattttag
     2521 tcttaggtgt tgattgcatg atgaatgcag aagttatacc tgcagccata ttagcacctt
     2581 cattattgtg tataatttga atattatttg cttttaaagt atgtccaatt aagtttgaag
     2641 tcgttgtttt accatttgtt ccactgataa atacaatatc atcaacttgc tctgctaatt
     2701 ttcttaatat atctgtatcc acttttctag cgatttgtcc aggtaaatct gttcctcttt
     2761 tacctactgc tctacttgct ttacgcgcca atttcgctag atggattgcc gtccactgtc
     2821 tcatgtgttt cctcctcaaa tttccactcg catcattata acatgacaag gcaacttcaa
     2881 aaaagtttct caatcacaaa ttgatacagt gtttctaaat tataatcatt ctcatttaga
     2941 taattaaaaa tgatatttat tctcaattaa atatcgctaa atgatacatt ttctcaatta
     3001 gagtgctaaa ataaggtgtt aaattataat tattattatt tacaattgag aatgagtttg
     3061 ttatactaag tttaattcat agtaatttta atttacaaat aagaggtgta tcaaaatgtt
     3121 aagtaaaaat ttattagaag cattaaatga tcaaatgaac catgagtact ttgcagcaca
     3181 cgcatatatg gcaatggcag catactgtga taaagaatcg tacgaaggat ttgcaaactt
     3241 cttcattcaa caagctaaag aagaacgttt ccatggacaa aagatttata actatattaa
     3301 cgacagaggt gcacatgcag aattcagagc agtttcagca ccaaaaattg acttttcaag
     3361 catactagaa actttcaaag acagcttatc tcaagaacaa gaagtaacaa gacgtttcta
     3421 taacttatct gaaatcgctc gtcaagataa agattatgca actatctcat tcttaaactg
     3481 gttcttagat gaacaagtcg aagaagaatc aatgtttgaa actcacatca attatttaac
     3541 tcgtatcggc gatgacagca atgcattata tctttacgaa aaagaacttg gcgctcgtac
     3601 attcgacgaa gaataattaa acatcactac aatagacaga taaatatcat acgacatgat
     3661 aggcatttgg gtcacttaca ataacccaat gtctatatta ttttgcttta cggagatcac
     3721 tagattcatt ttctgaatca ttgatctgcg ttttttcatt ttcaaggcta attattgtat
     3781 ttttagtcat ttatttttta aactactaat gttaataact ctaaatttga tgttgaatta
     3841 atttgaccga ttttaaagca tatcatcatt tactttttaa tcagagttac atccaaatga
     3901 tagatttcac gttatacctt cacgtataat attatgtatc gtttgtaagc aaatgactaa
     3961 aagtctatta atatatacat ttaattaatt gaaaggattg actacatgat acaagatgcg
     4021 tttgttgcac ttgattttga aacagcaaat ggtaaacgta caagtatttg ttctgtcgga
     4081 atggttaaag tcattgatag tcaaataaca gaaacatttc atactcttgt gaatccgcaa
     4141 gactattttt cacaacaaaa tattaaagtt catggcatac aaccagaaga tgttgaaaat
     4201 gcacctacgt ttgactacgt atttccatat atgatgcaat ttattgcaga tttacctgtt
     4261 gtcgcacata acgcggcatt tgatatgaac gtcttacatc aaagcattca aaatattggt
     4321 ttaccaactc caaatttaac ttacttttgt agttatcaac ttgctaaaag aaccgttgat
     4381 tcgtatcgat acggtttaaa acatatgatg gagttttatc aattagattt tcatggtcat
     4441 catgatgcat tgaatgatgc caaagcatgc gcaatgatta cttttaggct actgaaaaat
     4501 tatgaaaatt taacatatgt aactaatatt tatggtaaaa atctaaaaga taaaggctag
     4561 gactaaataa aatactccct tcaaaagtaa gcattgtaaa aatgtaaact ttgcagggag
     4621 ctttatttta tataaagtca tatatcgtca tatttttata agttgattgt tctaaattac
     4681 ctacagtgac accaataagt cgaattggta catctgggtc ttttaaatcg ttataaagta
     4741 aatatgcaat attataaata tcttcttcag aactaaccga atctcttaaa ctcatctgtt
     4801 tagatagcgt ttcaaattga taagttttaa ttttaaccgt tacagtttta gctgacttct
     4861 gtaatttatt tagacgttca gctgttttac ctgacaattc ccatactttt cttaaaatct
     4921 cttcatcatc attcacgtct gttgcaaatg tgcgttcagt ccctactgat tttcttactc
     4981 ttgatgattt cacttcacta tggtcaatac cgcgtgcctt gttatataaa ccccgacctc
     5041 tttttccaaa caaacgtatt aattcaaatt ccgttttctc atataaatct ctaccgttaa
     5101 aaataccatt atcatgcatt acttttttgg aagctttacc tacgcctgga aaatctccaa
     5161 tatccaatgt catcaaaata tcatggacat tttgataatc aatcacagtc aaaccatcag
     5221 gtttattcat accactcgct aatttagcta aaaatttgtt ataagaaaca cctgcagatg
     5281 ctgttaaatg tgtctgctct agaatatctt ttctaatata ctgagcaatt ttcgaagcag
     5341 gaaggtctgg tctcactaat tctgtaatat ctaaatacgc ttcatccaat gacatcggtt
     5401 ctaccttatc tgtataactt cggaaaatag acataatctg cgcagatgtt tctcggtaag
     5461 caccaaaatt acttgtgaca aagtatccat ttggacataa tttatgcgct tgtgacatag
     5521 gcattgctga atggacgccg tattttcgtg cttcatagga tgccgtagag acaacacccc
     5581 tactgcttgc tttaccacca acaatgactg gtttcccttt caatttgggg ttatctctca
     5641 tttcgacttg tgcaaaaaaa tagtccatat ctatatgaat aattcgtctc tcagtcaagt
     5701 gctcacctcc ctactaattt ttacttttat aacgcacaaa aatatctcaa cataattata
     5761 cgctgtgtac gattttttta cataaatctt gcacttagcg ataactatat tgagataact
     5821 acaagttgtt ataaaatcaa ttgctattta agcatgatga tgaagacgat tgagtaagaa
     5881 aacataggta atctgaaata attcaagcaa attcattttg ttggtatcat catattaaaa
     5941 tttattattg agtcggcttt tgatgataca aataaatact atcttcatct tgttgaacat
     6001 atttaaaact actagatatt gttaatgcaa caagcagaat atctataaag caataagcag
     6061 tatgcatact aaacataaaa ataagtgatg aataaccaaa taccttaatt aaaataagca
     6121 agccagtact taataggaat agtggtgaca gcataataat tgagaattgc catttgttga
     6181 agcaagcatc tgctgtttgg aataagattc tgtctttttt tatattaaac ataggtttgc
     6241 tatctttttt aaataaaaga aataatgctc tatggataag ttcatgtaaa atcaataaaa
     6301 taatgaatcc agcaaaccca tatacaagat tgatgatgat attttgatcg acaaccgctg
     6361 tgacacctaa cgcccactta tacgtaaata aaatcacgaa taacgcaata acaagttgca
     6421 agataataaa ccttcgcatt tgaaaattat ttgtcgttaa atcaatttta tgcattacca
     6481 accctcccga tcatgacatt cttattcttc tttaaatata gtatacaatg tcacatttaa
     6541 tttaaaaagt tcatatcaag aaagtaaatt ggctgtaata aaattttaat gtacgacttc
     6601 tttcttcact tattaaggcg aaattttatc tcaaatcatg tgcgctattt caaattgaat
     6661 aatgccactg tctcaacatg tgttgtttgt ggaaacatat ctaccggtgt tacctcttca
     6721 agttgatatt tttcagctaa taataatgca tcacgttgct gtgttgcggg attacatgaa
     6781 atatagacaa tacgcttagg ttctaatgta agcaaagtct gaataaacgt ttcgtcacag
     6841 ccctttcttg gcggatcaac cattacaaca tctggtttaa tcccttgtgc tttccattgt
     6901 aaaataactt cttcagcttt cccacagaca aaagttgtat tattgcattg gtttatagtc
     6961 gcattttgtt gtgcgtcttc aattgcagaa ggtactactt caacaccgta tacatgtttt
     7021 gcatgtggtg ccatatatag ccctattgtt ccaataccac aataggtatc taatacaact
     7081 tcattacctg tcaattgcgc atactcaatt gctttattat ataatttctc tgtttgttca
     7141 gaattaattt ggtagaatga ctgatcactt attttaaatg tactatctgt taattgatca
     7201 ataattgtat ctttaccata tagcgttata gactgacgtc ccataataac attagagtgg
     7261 ctatcattaa tgttttgttt aatgcttgtc acattaggaa atgcatctaa tatcttctca
     7321 acaacagcat ttttttgtgg ccacttttta ccattagtta caaaaataat catcatttcg
     7381 tctgtatgat atcctgttct tacaaccaaa tgtctcatta aacctttttt caattgttct
     7441 tgataaatac ttacatttaa atcttttaaa atagatttaa cttcattcat cacttcttga
     7501 tgttgtgaat cttgtattaa acaactttcc atgtcaataa tgtcatggct tctttgacga
     7561 taaaagccca taataacttc attctgttca ttcttaccaa ctggaatctg ggacttgttt
     7621 cgatatcgcc aaggatctgt catgccaact gtatcgttaa acttagaatt atcaaaatgc
     7681 gcttttcgct gaaacaaatt aatcacttgt tcctttttca tttcaagttg tgcttcgtat
     7741 gataagtgtt gaagttggca cccaccacaa cgttcataat atatacatgg cggtgcaaca
     7801 cgattctcac ttctcgtatt tatattaagc aacttaccta tcgcaaagtt cttttttact
     7861 ttgataattt tatattcaat ttgttcatta attaaagctt gtggtatgaa aataggaaag
     7921 cgatctattt ttacaacacc atggccttca tgcgttaaat caacaactgt tcccattttt
     7981 atgtcatttt tagctattgc ttgcaaaatt ttacctccaa aatgaacagg ttaggaacaa
     8041 aattatgcgc ttcctaacct gccattatat atttcactat ttctgtttat tcttcgatta
     8101 aattgtcatc aacatgatca ttatttatta actcttcatt tacaatatca ttaggtgcaa
     8161 agacatctat atgacgttct agatttaaga aattcgctgg taatttacca ccatattctc
     8221 catctacatt tagttgtaag tctgtgaatg atgaaatatt aattgccttt gctttttcat
     8281 aaataacttt aggatgctta gtatgttctc ctcttgaagc taaagtcata atatgaccaa
     8341 gttctgcaag gtttgatttt tcaactataa ttaacgtaaa atagccgtca tctaacttag
     8401 cgtccggcac taatttttca aatcctgcca ttgaatttgt taaacctaaa aagaataata
     8461 atgcttctcc ttggaaaaca ttaccatcat attcaattct taaatctaca gctttcattt
     8521 gaggtaacat ttcgaaacct ttgatgtaat aagcaaatgg accaacaata gatttcaatt
     8581 tactcggtgt ttcataagag acttgcgtca attgtccgcc tgcagctaaa ttaataaagt
     8641 atcgattatt cattttacca atatctactt tagtagaatg accttcaatg atgacatcaa
     8701 gtgcccccat gatgtcatta ggtatatgca atgcacgtcc aaagtcatta acagtaccca
     8761 taggaatgac acctaactta ggacgattag gcttttctgc gataccatta actacttcat
     8821 ttaatgttcc gtcaccacct gcagcgatta atacatcata attttcatgc atagctcttt
     8881 ctgcttcaag tgtggcatca cctattttct cggttgcata tgcactcgtt tcatatcccg
     8941 ctttttctaa ttttattaag gcatcaggta attctctttt aaatagctct ttacctgatg
     9001 tcgggttata aatgattcta gcacgtttcc tcatatctta tccctctact taaaattcat
     9061 atattttaac ttcatcttgg tttcgtctaa tagggagtgg gacagaaata atatttaaca
     9121 aaatttattt cgttctaccc caacttacat tgtctgtaga atttcctttc gaaattctct
     9181 ttgttgaggg ccccacccca acttgcacat tattgtaagc tgacagaaag tcagcttcta
     9241 tgttggggcc ccgccccaac ttgcattgtc tgtagaattt cctttcgaaa ttctctttgt
     9301 tggggccccg ccaacttgca ttgtctgtag aattttcttt cgaaattctc tttgttgggg
     9361 ccccgccaac ttgcattgtc tgtagaattt tctttcgaaa ttctctttgt tggggcccca
     9421 ctagaattga aaaaagcttg ttacaagcgt attttctttc agtcaactac tgccaatata
     9481 acattgtagt gcctaggaca ttgaatttat gacccaggct cagtcttatt tcatcattct
     9541 taatatcgtt aaagaccaac ttgtatctta aacaaatact atctcaatat gtacaaaggt
     9601 tgttatttat tcagcatttt ttgccgttct tcgttatata gacttcgtca gttatgctat
     9661 tttaccttta aaatgatgtt gtaaatataa tgttgtcttt atacaaaaat gttttatacc
     9721 tttttattat acagtttgcc ttaatataat taaagctaac gcattaataa aattaatatt
     9781 tttaccatta acatgtacaa tgaataaagt taaaagtaat atgacttcta tagatataaa
     9841 taaaccctcg attgcatcta agtcagcaat caagggtata ttttttaaat cttcatagtt
     9901 tgatgattta aattatcttt tatctaattc ttgttttaat agttgattta ctaattgtgg
     9961 attagcttga cctttagacg ctttcataat ttgaccaact aagaagccca tagctttgcc
    10021 tttaccattt ttgtaatctt caactgattg ttcgttattg tctaatgctt catttacaaa
    10081 ttttagaagt gttgcttcat cagaaatttg aactaagcca ttatcttcca taatctgttt
    10141 agcattacca cctttagctg ctaactctgg gaagactttc ttcgcaattt tactgctcat
    10201 tgttccgtct tcgataagtt taatcatacc tgctaaattt tctggtgtta atttagtatc
    10261 taataattct acttgatttt tatttaaata ttcgtttacg ccacccatta accagttaga
    10321 tgttaattta acatctgcac cgtgttcaat tgttgattca aagaaatctg acatttcttt
    10381 agtcaatgtt aatacgtgtg catcgtatgc aggtaaacct aattcattta catacttagc
    10441 tttacgctca tctggtaatt caggaattgt ctgacgaaca cgctctttcc aagcatcatc
    10501 aatatataaa ggtacaatgt caggctctgg gaagtaacgg taatcatcag aaccttcttt
    10561 aacacgcatt aaaattgttt tacctgtaga ttcatcaaat cgacgtgttt cttgtccgat
    10621 ttctccacca tttaacaatt cttcttcttg gcgtttttct tcatattcta aacctttacg
    10681 tacatagtta aatgagttta agtttttcaa ttcggcttta gtaccaaatt tttcttgacc
    10741 atatggacgc aaagagatgt tagcatcaca acgtaaagat ccctcttcca tcttaacgtc
    10801 tgatacacca gtgtattgaa taattgaacg taatttttct aaatatgcat atgcttcttt
    10861 aggtgaacga atatctggtt cagatacgat ttcaattagc ggtgtacctt gacggttcaa
    10921 gtcaactaat gaatactcac ctttatgtgt tgacttacca gcatcttctt ccatgtgaag
    10981 acgagtaata ccgattcgtt ttgtttcacc gtcgacttcg atatcgatat atccattttc
    11041 accaattggt tgatcaaatt gagaaatttg atatgccttt ggattatctg gatagaaata
    11101 gtttttacgg tcaaacttag attctgttgc gatttccata tttagtgcca ttgcagcacg
    11161 cattgcccag tctactgcac gcttattaac aactggtaag acacctggat atgctaagtc
    11221 gataacattt gtatttgagt taggttctgc tccaaaatgc gctggtgatg gagaaaacat
    11281 ttttgagtcc gtttttaact ctacgtgaac ttcaagtcct ataactgttt caaaatgcat
    11341 gatttccact ccttataatt tttcataaac gtcatgtaaa ttgtattgtg tttcatattg
    11401 ataagcgaca cgatataacg ttttttcatc gaatggttta ccaatgaact gtaaaccgat
    11461 tggtcggcca tttgattgtc cacaaggaac agaaatacca ggtaatccag ctaagtttac
    11521 tggtgttgtt aataaatcat tggcatacat tgttaatgga tcatcaattt cttcacctaa
    11581 attaaacgca gttgtaggcg ctgttggacc aactactaca tcataatttt cgaatacttt
    11641 atcaaagtca tttttaatca atgttctaac tttttgagat tttttatagt aagcatcgta
    11701 gtaacctgaa cttaatgcaa atgtacctaa gaaaatacga cgttttactt ctttaccgaa
    11761 accttcagat ctcgacattt tatataattc ttctaatgaa tgagcttctt tagaatgata
    11821 accataacga attccgtcaa aacgagaaag gtttgacgaa gcttctgatg atgcaatcac
    11881 gtaatatgat ggaataccaa atttagtatt tggcaatgat acttcctcaa cgacagcacc
    11941 taaagatttt aaagtttcta cagcgttttg aactgcttct tttacgtcat cagctacacc
    12001 ttcacctaag tattctttag gtaatgcaac ttttaatcct ttaatatctt taccaatttc
    12061 agatgtaaag tctacatcat caacaggtgc acttgtagag tcattagcat ctgcaccaga
    12121 aatagcttct aatacgattg cattatcttt tacatttcga gtcaatggac caatttggtc
    12181 taatgaagat gcaaatgcaa ctaatccaaa tcgagataca cgaccgtatg ttggtttcat
    12241 accgacaacg ccacaatatg cagccggttg tctaattgaa ccacctgtgt ctgaacctaa
    12301 gctaaatggt actaagccag ctgcaactgc tgctgcagat ccacctgatg aaccacctgg
    12361 tactgcttta tggtcaaatg gattaactgt ttttttgaaa taagatgttt ctgttgaacc
    12421 gcccattgca aactcatcca tatttaattt accgattaaa acggcattct cattatgtag
    12481 tttttccatt acagtagatt cgtaaattgg cacaaaacct tctaacattt tacttgcaca
    12541 tgttgtttct aatccgtttg taataatgtt atcttttata cccattggaa taccaaataa
    12601 tttgccatcc atttggtctt ttgcttgtaa ttcatccaat tcttgcgctt ttttaattgc
    12661 attttcttta tccagcgcta gaaaagactt gattgttgga tcagtctctt caattgcatc
    12721 atatatatct ttaacaacat cagatggttt gatttttttg tcttttatta aagttaataa
    12781 attctcaacc gattcgtagc gaatgctcat cttacgcgtc ctcctcattc atgattgtag
    12841 gcactttaaa ttgtccatct tctgtttctt tggcattttt caaagctaat tcttgcggaa
    12901 tacctttaat tgctttatct tcacgtaaaa cgttttgtaa atctaaaacg tgatatgtag
    12961 gttcaacgcc ttctgtatca gcgctatcat tttgttttgc aaaatctaaa atgctttcta
    13021 atgtgttggc catttcttcc gtttcttcag gagaaatttg aagtcttgca agattcgcga
    13081 tatgctcaac ttcttcacgt gttacttttg tcattaataa aagcctcctt taagtcattc
    13141 atcactaaat tgtatcaaat ttccaattaa aaatctaagt atttatgagg tactacttta
    13201 atttcatata aactgtataa acattatcat tcatttatca aatcattttt tataaaaaca
    13261 acacccttta atattagaca acccaattca atattatgat tatgcaattt taattataaa
    13321 aatttgccca tatccaaaaa atacgaaagc gttttctata ttgatataca agtatttcaa
    13381 aaagaataaa tttaattttc ctacttttct aaacatttat ctttatgtat aatgttttca
    13441 agtaactaaa ttataaatta aataaaggga gtgtttatca tgcttacaat ggggacagca
    13501 ttaagtcaac aagtagatgc caattggcaa acttatatta tgattgccgt ctactttttg
    13561 atactaatcg ttattggctt ttacggttac aagcaagcaa ctggtaacct aagcgagtac
    13621 atgttaggtg gacgtagtat tggaccgtat attactgcat tatcagctgg agcttcagat
    13681 atgagtggat ggatgattat gggtctacct ggctctgtct atagcactgg tctatcagct
    13741 atgtggatta caatcggttt aacattaggt gcttatataa attactttgt tgttgctcct
    13801 agacttcgtg tttataccga attagctgga gatgcaatca cattaccaga tttctttaaa
    13861 aatagactaa acgataaaaa taatgttcta aagattattt ctggattaat tatcgttata
    13921 ttctttactt tatatacaca ttctggtttc gtatctggtg gtaaattatt tgaaagtgct
    13981 tttggattag attatcattt cggtttaata ttagttgctt tcattgtcat tttctatact
    14041 ttctttggtg gatatttagc tgtatcaatt acagatttct tccaaggtgt cattatgtta
    14101 attgcgatgg ttatggtccc tattgttgct atgatgaatt taaacggctg gggaacgttt
    14161 catgatgtag cagctatgaa acctacaaat ttaaatttat ttaaagggtt atcatttata
    14221 ggaattatct ctctattttc atggggatta ggttatttcg gtcaacctca tatcattgta
    14281 aggtttatgt ctattaaatc acacaagatg ctacctaaag ctagacgttt aggtattagc
    14341 tggatggcag ttggtttgtt aggcgctgtg gctgttggtt taacaggtat tgcattcgta
    14401 cctgcttatc atattaaact agaagatcct gagacattat tcatcgtgat gagtcaagta
    14461 ctcttccatc ctcttgtagg tggtttctta cttgctgcga ttctagctgc aattatgagc
    14521 acgatttctt cacaattact tgtaacatct agttcattaa cggaagactt ttataaatta
    14581 attcgtggtg aagaaaaagc taaaacgcac caaaaagaat ttgttatgat tggacgttta
    14641 tctgtattag cagtagcaat cgttgctatt gcaattgcat ggaatccaaa tgacacaata
    14701 ctaaacttag taggtaatgc ttgggccgga tttggtgcat cgttcagtcc acttgtgcta
    14761 tttgcacttt actggaaagg tttgacacgt gccggtgctg taagtggaat ggtttcaggt
    14821 gccttagtcg ttatcgtttg gattgcgtgg attaaaccat tggcacatat caacgaaata
    14881 ttcggcttat atgaaattat tcctggattt attgtaagtg taatcgttac atatgttgta
    14941 agtaaactta ctaaaaaacc tggtgcattt gttgaaactg acttaaacaa agttcgtgac
    15001 atcgttagag aaaaataatt cataagtctt aacaaattaa aaaggtacta atgttaatca
    15061 aaattctgac taacattggt acctttttat tatctttaat ttacaattaa ttactataaa
    15121 tgtgaacttg cggttctttg tcatcttttg tcttactaat taaagctcgt ggttggttac
    15181 catctttaat acgaatttca tagttatcga ttttatcgaa atatttattc gcttgttcag
    15241 taacgtactg tgtaatacca attgtttcag cttgtccata gtaatcgatt ggtaaatcta
    15301 ctactaatcg ttgtggcttt ttatcaacaa atttaacttt ccctactgct tgtgtgaaat
    15361 tagaaaaata tgattgcaaa ttatcattaa attgcttgaa attattattt aaattttcat
    15421 cataatctgc tgctgttgaa gaaggtaata aagctgattt ttcattgata ttatgccatt
    15481 cattaagctt tgtttgactc ttttctgcag tcgcttgagt gataaattca cctggtgtga
    15541 ttgaatcttc acttgattgc ttataaattg caaaatgaat tggtatatct tttaaatcat
    15601 cattttcacg taaccttgat aatatctcac tagccatttg tttaccttgc tttttaactt
    15661 cgctatcatc tagtttttta ctaaaagtcg gtccatcttt ttctttttta tagtaataaa
    15721 cactattcat agctaaacca atcgtcatac ctttaatatt cttacctttt gtatctccac
    15781 caccataaaa atcttgctct aaaatgttag ataaataggc tggtgatttt tctgcaatct
    15841 tttcaggatc tgtttcacct tcgtgtgatg gattaagtcc taaattttca ttcgctttct
    15901 tgtctttttt atctttttca gacattttat cgatttcacg ttttgtatac ttaggattta
    15961 aataggcatt aattgttttc ttgtccaaaa attgaccatc ttgatacaaa tatttatctg
    16021 ttggaaatac ttctttactt aagttcaata aaccatcttc aaagtcgccg ccattataac
    16081 tatttgccat gttatcttgt aaaagtcctc ttgcctggct ttctttaaat ggtaacaatg
    16141 tacgatagtt atcaccttgt acatttttat ccgtagcaat ttcttttact tgatttgaac
    16201 tattgttatg tttttgatta tcttttccag cctggtcatc cttatggtta ccacaagcag
    16261 cgagtataaa gatagctgta atcaataata ctaatgtacg cttcatcgac atacccctct
    16321 aactatttaa ttcattttgc ttatctacaa attgttgctc tgtccaaatt tcaataccta
    16381 aactttgtgc ttttgttaat tttgaacctg catcttcacc agcaataacg acatctgtat
    16441 ttttagtaac gctacttgta actttagcac cttgtgatgc aagccattta gatgcttcat
    16501 tgcgtgtcat ttgatgtagc ttaccagtta gtactatcgt tttaccacta aattcaggat
    16561 gtccttcaat atctgatgtt ttgatacctt tataaatcat attaacatgt ttatctttta
    16621 atttttgaat taaagcacga atatcttcat tttctaagta agtaactaca gattgtgcta
    16681 ctttatcacc tatatcatga atttctacta attccgcttc agttaccgtt agtaatcgat
    16741 ctatcgtttc atatttttct gctaacactt ggctcgcttt aacacctaaa tgcctaatac
    16801 ctagaccaaa taataaattt tctaaagagt tgtccttagc ttgttgaatg gcagctaata
    16861 aattatcaac ttttttctgc cccattctgt ctaaaggtaa taaatcttct tctgttaaat
    16921 agaaaatatc agcaacatct ttaattaatt cactttgata aagctgttga ataattttag
    16981 tgcctaaacc atcaatattc atggcttgtc ttgatacaaa gtgaatcaat ccttcaacaa
    17041 gttgcgcttg acattttgga ttaatgcaac gaagtgctac ttcgccttca atacgtacta
    17101 attcatgtcc acaacttgga caatgggttg gcatatgata tgtgacagca tcctcaggtc
    17161 tacgttctgg aatactacgt acaacttcag gtatgatgtc acctgctttt ttcactacaa
    17221 cactatcacc aattcgaata tctctgtcat gaattaaatc ctcattgtgc aaagatgctc
    17281 ttgatacagt tgtaccagct acttttactg gttctaaaat agcagtaggt gtgactacac
    17341 ctgttcgtcc aatacttaat tcaatatcta ataatttagt tactacttcc tcagctggaa
    17401 atttataagc aatggcccat ctaggagatt tttgtgtgaa tcccatctca tcctgttgat
    17461 ctaaatcatt aaccttaata acaatcccat caatatcata aggtaatgac tctctttggc
    17521 ttgtccattt ttcaatatac tctaaaacac catcgatatt atttacacgc gctctatttt
    17581 tattcgttgt aaaacctaat ttatctaact catctaatgc ttcactttgc gaacgcgcat
    17641 tgaaatcagt gaaatcattg acactatata taaatacgct tagctttcgt tttgccgtta
    17701 atttagaatc taactgtctt aatgatcccg cagcagcgtt tcttggattt gcaaataact
    17761 gctcatcatt tttttctttt tcttcattta atcgtaaaaa tgaacgtctc ggcatatatg
    17821 cttcaccacg aacttctaca tttaatggtt ctttcatttt caaaggtatc gcatgaattg
    17881 tttttaaatt ttcggtaata tcttcacctg ttgttccatc accacgtgtt aaaccttgaa
    17941 cgaagtatcc atcaacatat ttcaatgata ctgctaagcc atcaattttt aattcgcaca
    18001 tatattcaac gttgccaatt tgttcacgta tgcgttggtc gaattttctc aaatcatcct
    18061 cattaaatgc attccctaaa cttaacattg gcgtgtcatg gttgacttta ttgaaagagg
    18121 cttgggcttc accaccaact ctaactgttg gagaatctac agtcttatac tcaggatgct
    18181 cctcttctat tttaatcagt tcatgaagta atttgtcata ttcactatct ggtacagatg
    18241 gattatcctc tacatagtat tcataactgt attgatttaa taaatcatgt aactcgttca
    18301 cacgagacga taaatcagcc atcccttaat cctccttttt ttcaattggt gcaaattgcg
    18361 ctaacaaacg ttttggccct tgtgatttaa agataatatc tagttcgatt gagccatttt
    18421 tctcgtttac attactcacc atgccttctc cccaggcttt atgcatcact ttgtcaccta
    18481 cattccaatc agatgacgat acttgttttt tcgttgacgt tgttcgttga ctaaatccgc
    18541 gtttagcaaa aggttttgcc ttaggttgta tcgtttgtcg tttgccactt gaatgatttt
    18601 ctaatagtga ttctggaatt tcctttaaaa atctagatgg catatttgac tgagggcgac
    18661 caaataacat tcttgatgtc gcatgagtga tatataacac ctcttcagcc cttgtaattg
    18721 ctacataaca aatacgacgt tcttcttgca tttcgtgatc atcttcactc ttaatcgctc
    18781 taatatgtgg gaataaagat tcttccatcc ccattataaa gacaattgga aattcaaggc
    18841 ccttagccga gtgcattgtc attagtgtta cgccattttc agtatctgcc tcatcaatat
    18901 cagctactaa cgataaatcc gttaaaaagt taattaatga ctgttcttct aatggggtat
    18961 tttcctcata gtcttttggt actgacataa attcatcgat gttttctaat ctacttcgag
    19021 attctaatgt attttcacgt tcaagcattt ctcggtagcc agacttttgt aatacttcgt
    19081 caactatttc atgaatttct aaaaattctt gttcttttat caagctttgg atcaactcgt
    19141 aaaaattaag acactcttgt gtcacttttt ttgacaatcc gataaaatca gcttctccaa
    19201 gtgcatcaaa catactgata ttgttttgaa gtgcatagtt ttgaactttt tcaacagatg
    19261 aaggacctac acctcttttt ggaacattaa taatacgttg caaactaatg tcatcattac
    19321 tattggcaat tatacgcaaa taacttaata aatctttgat ttctttacgg tcatagaact
    19381 tttggccacc aaccattgtg tatggcatat tagatttcat gaatgtttcc tcaagtacac
    19441 gtgattgtgc atttgttcta tataaaattg ccatatcttg atatttctta ccattacgtt
    19501 gatgcttcat aatttctcgt attacaaatt ccgcttcatc acgttctgtc attgcttcat
    19561 agtaatgaat tttctcacca ttcgtatttg cagtccacag tccttttggc ttacgttcag
    19621 aattattttt aatcacttcg ttagccgcat ttaaaatcgt tttcgtcgaa cgataatttt
    19681 gctctaaaaa gattgtattc gcttctgggt agtctttttc aaatgataag atattttgaa
    19741 tatcagcacc acgccaacca taaattgact gatctgagtc acctacaaca cataagtttt
    19801 taaacttact tgctaataat ttaactaatg tatattgtgc tttattagta tcttgatact
    19861 catctacatg aatatattgg aatttgttct gataatattc tagaacttct ggtacacgct
    19921 caaataagtt aatcgttgtc ataataaggt catcaaaatc taacgcttca ttacgcgaca
    19981 attggcgttg atatccacta taaaccgttg ctaccatttg cgagtgataa tctgtggctt
    20041 ctttttgagc atctgcaggt gttttaagtt catttttcaa attactgatc gcaccgataa
    20101 acatacgagg ttcaaacttt ttactatcaa tattttcatt ttttaagacg tctttaataa
    20161 cagatttttg gtctgtagga tcaattatcg taaaattgcg ttctatacct attcgatctg
    20221 catcacgacg taaaatacga acacacattg agtggaatgt tgacatccaa ataacttctg
    20281 cttgatcacc tactaatttt tgaacacgtt ctttcatttc tcttgcagct ttatttgtaa
    20341 aagtaatagc caaaacattg tatggtgaga catctttttc gtctaataaa taagcaattc
    20401 tatgtgttaa aacacgtgtc ttccctgaac cagcacctgc cataattaac aatggtcctt
    20461 ctgttgtctt tacagcttca ctttgctctg tattcatatg atttaataac gcattcattt
    20521 actagactcc tttattttta ctgtttttaa agctttttta atatctttat aaataatatc
    20581 accgacgata attgtatctg caatagctgc catctctgtc gcttgttgtt ctgaggaaat
    20641 accgccacca taaaaaagtt gcgtttctgt tagatgttct gagacagctt gaacctttga
    20701 tacgtcgcca taaatgccac tatactctat atacataacc ggtaatcgat acatatgatt
    20761 gaccatttgg gcatatgctt ctaaatcttc tgttgttaaa tctgtatttg ctttggtatg
    20821 ttttgccact ttgctatcag cattgcacac gacataccct tcaaatatta cttcttcaaa
    20881 atctatacta tgtccatatg ttttaagcgc ttctaataat ataccattgt gaaatgcaac
    20941 atctgtactg ttcagtactg taggtacaaa ataaaaatca aaaccaggca ttacactttc
    21001 gatgtttgat atttcaagta ctaaaggcaa tgggtatctt cttaccctgc tcattaaatg
    21061 aatgacatta tcttcagtaa cgtcatcagt tccaccaatc ataattgcat ctgtttgaga
    21121 catacaaatc gcatctaaat catcatctga aatatgttta gctgggtcta atttaaaaat
    21181 atggcgccat tttttaatgt catacatttt ccgaaactcc ttttttaaca tacatatgat
    21241 tatagcattt ttaagtgtcg agttctaaag acttaatatg aattttaagt tcttttactc
    21301 tgtaaatttt ttcgtgaaaa aacaatgatt atctacctta ttagtgcaga tagataacca
    21361 ttgtttatcg ttcatttatt attcatttgt ttcaatattc atacgatcta aaatcattgt
    21421 ataagcatca ttaccccatt gtaatgaacg cttcactcta gaaatcgttg cagtcgatgc
    21481 tccagattct tgttcaatcg ttgcataggt ataaccttgc ttaatcattt tagcaacttg
    21541 taatctttga gacagtgatt gaatttcatt tacagtacac aaatcatcga aaaattggta
    21601 acattcttct ctattttcta acgttagtat tgcatcaaac aattcatcta acgctgcacc
    21661 tcgtaatttt tcaatttgca tatcgaaaca acccctataa ttttattctt tatgtcattt
    21721 taacgcatta acctattaaa gtgtagcgat ttatatttta ttaaatctga atcgttactt
    21781 tatttaattt tatgctaatc cagcgcgttt gaaaatagtg tcaacttgat tcaaatgatg
    21841 tttaggatcg aaacattcat ccaattcttc ttttgttaaa acacttgtaa tagactcatc
    21901 ttgttcgatt aattcacgga aaggtgtttt cgtttcccaa gatatcatcg cttttggttg
    21961 tactttgtcg tatgcttctt cacgaaccat acctttatta attaatgcta ataagacacg
    22021 ttgtgagaaa atcagaccaa atgttttatc tatgttatta cgcatattat cttcaaatac
    22081 agttaaacgg tccacaatat tcgtgaaacg attcaatgca taatctagtg ctattgtaac
    22141 atctggtaac ataatacgct cagctgaaga atgagaaata tctctttcat gccataatgg
    22201 cacattctca taagctgtag taatataacc acgaatgact cttgaaatac ctgtgatatt
    22261 ttcagagcca attggatttc gtttatgagg cattgcagat gaaccttttt ggccttttgc
    22321 aaatgcttct tcaacttctc ttgtttcggt tttttgaagg ttacgaattt caacggcaaa
    22381 tttttctagt gacgtcgcga ttaatgctaa tgtcgcaatg tagtatgcat gtcgatcgcg
    22441 ttgcaatgtt tgcgttgata caggcgctgt gccaatacct aaatgtttac acacataact
    22501 ttctatttca ggaggaatgt tagcaaaagt acctactgca ccactcattt tccctacttc
    22561 aatttcttct cttacttgtt tgaaacgttg taagttacgt tgcatttccg tgtaccacaa
    22621 tgccattttg acaccaaatg tagttggttc tgcatgcact ccatgtgtac gtcccatcat
    22681 caatgtatat ttataatttt ttgctttttc agctaaaacg tcgataaatc tttctaaatc
    22741 tttttcaata atgtcatttg cttgtttaat aacgaaactt aaagctgtat ctacaacatc
    22801 agtagaagtt aaaccataat gtacccactt acgttcttca cctagcgttt cagaaacttg
    22861 tctagtaaag gctacaacat catggcgcgt ttcttgttca atttcttgtg cacgttcgac
    22921 atttaccttt gcgttttgac gaattttttg tacgtcagct ttcggtatat gtcctaattc
    22981 actccatgcc tcacatgcta aaatttccac ttctaaccat gcttcatagc gattttgatc
    23041 agtccaaata tcagacattt cttctctaga ataacgttca atcatttttt taactcctat
    23101 cgtatgtata ctcgaatttt caaaaacaga acatttttaa taaaaataaa taaaaagttc
    23161 gtttttaact ctactcttca cagtttaaca gaattggtta taaatgtata aaaaatttcc
    23221 gtatattctc attctatttt attttttaca ttaatacaat tatctatggc agattaatac
    23281 tgatttctaa ttgtaaatgt tcgcaacact ttaatctaac tggtatttat aatgatccat
    23341 taagaatata atattgcatt ttaatttttc tcccctcaac tacactatcc aactttttat
    23401 tacaattagg acaatcaata gctttagtaa taccagattt tattcacttt acttctccta
    23461 ttgtatggaa ttttcaacaa tctactttac ctagtttcat aatattcctt cttacattcc
    23521 ataatgcctt ttaaaattat tcgcttctaa tttaacaaat tttctactca caaaaagaat
    23581 atatgttcta ttgcataggt gtagcatttt aaacataagc cattaatatc gacctccaga
    23641 atcgtataaa tacgaaactg attatagaaa aatacgcaga gattttctta atagtaaatt
    23701 tttatagaaa gacataaatt gactacgctt ctttcgaaat cgactaatat attttcatga
    23761 aactttcgat catattaatt attgaatgaa atgtttacaa tttagtaaat a
//
LOCUS       DAPSKH010000043        23041 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPSKH010000043 DAPSKH010000000
VERSION     DAPSKH010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 23041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23041
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.043"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..81)
                     /locus_tag="RPH49_001801"
     CDS             complement(<1..81)
                     /locus_tag="RPH49_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5124942.1"
                     /translation="MNNEQKEVIEHVVYQLELSVMNNLESY"
     gene            complement(74..220)
                     /locus_tag="RPH49_001802"
     CDS             complement(74..220)
                     /locus_tag="RPH49_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5124943.1"
                     /translation="MKIYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGG
                     LENE"
     gene            complement(217..534)
                     /locus_tag="RPH49_001803"
     CDS             complement(217..534)
                     /locus_tag="RPH49_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5124944.1"
                     /translation="MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNL
                     SKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLE
                     ARQ"
     gene            complement(539..757)
                     /locus_tag="RPH49_001804"
     CDS             complement(539..757)
                     /locus_tag="RPH49_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5124945.1"
                     /translation="MTILANTRKFKEGMFLKGFNLSDLSRETGVGISYLSQIINGKKI
                     PSPKLAKKMAEVLQVEVNELFEFEVKEA"
     gene            930..1604
                     /locus_tag="RPH49_001805"
     CDS             930..1604
                     /locus_tag="RPH49_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5124946.1"
                     /translation="MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRY
                     DAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIEN
                     FDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSL
                     SAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSS
                     DIFKEY"
     gene            1618..2790
                     /locus_tag="RPH49_001806"
     CDS             1618..2790
                     /locus_tag="RPH49_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002476300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDY5124947.1"
                     /translation="MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHA
                     EMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAINHAIERFNNKP
                     IQTINKHEYQRFVNDISAQYSKNYVDSIIASTNMIFKYAYDMKLIRIMPSEGIKRPKK
                     KISVEELEDTEIHKKFLEKDELFQFLEVAKNHHSPQNSFEVFCTLAYTGMRAGELLAL
                     KWSDIDFENNTINITKTYYNPNNNKKQFQILTPKTESSIGKISVDPHVIKLLKNYKVD
                     VQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTDITNKQISTHSFRHTHC
                     ALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF"
     gene            complement(2859..4475)
                     /gene="groL"
                     /locus_tag="RPH49_001807"
     CDS             complement(2859..4475)
                     /gene="groL"
                     /locus_tag="RPH49_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500736.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDY5124948.1"
                     /translation="MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFT
                     APLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEG
                     LKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYI
                     SEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYI
                     LVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKA
                     PGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGD
                     GDENSIDSRVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKL
                     RIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQ
                     IAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVA
                     AMFLTTEAVVASIPEKNNDQPNMGGMPGMM"
     gene            complement(4551..4835)
                     /gene="groES"
                     /locus_tag="RPH49_001808"
     CDS             complement(4551..4835)
                     /gene="groES"
                     /locus_tag="RPH49_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDY5124949.1"
                     /translation="MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGT
                     GRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE"
     gene            5012..5755
                     /locus_tag="RPH49_001809"
     CDS             5012..5755
                     /locus_tag="RPH49_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDY5124950.1"
                     /translation="MTRLWASLLTVIIYLLSQFLPAVIVNTTQFAQYSDLEQLKAGIY
                     IQLVLFLIAATTIIFINFKIKDPTRLESEVKEPNKYIIPWALLGFALVMVYQFIVSIV
                     LTQIYGGQQVSPNTEKIIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGS
                     RIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRIAVPIIIHMLQNG
                     FVVIFQLLNPEALKKATEQANFIYHIFIP"
     gene            complement(5780..7039)
                     /locus_tag="RPH49_001810"
     CDS             complement(5780..7039)
                     /locus_tag="RPH49_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124951.1"
                     /translation="MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTN
                     LNHNITSPSVNSEMNNNETGTPHKSNQTGNEETGSNSRDANPDSNNVKPDSNNQNPSP
                     DSKPDSNNQNPSPNPKPNPDNPKPKPDPKPDPDKPKPNPDPKPDPDNPKPNPDPKPDP
                     DKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPN
                     ASDGSNQGQWQPNGNQGNSQNTTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYG
                     EVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALIT
                     GEIGSMPDLKKPEDKPDSKHRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCS
                     MMVVFSIMLFLFVKRNKKKNKNESQRR"
     gene            7236..7862
                     /locus_tag="RPH49_001811"
     CDS             7236..7862
                     /locus_tag="RPH49_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDY5124952.1"
                     /translation="MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHA
                     VKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSY
                     GTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYN
                     PLVDEMTSNEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK"
     gene            8132..8917
                     /locus_tag="RPH49_001812"
     CDS             8132..8917
                     /locus_tag="RPH49_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen family hydrolase"
                     /protein_id="HDY5124953.1"
                     /translation="MKVQIYQLPIIFGDSSKNEIQITQWFEKNMNAEVDVVVLPEMWN
                     NGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNNQIFNTAFSVNKSG
                     QLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSNGTYVTQLICYDLRFPELLRYPAR
                     SGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINP
                     NGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK"
     gene            complement(9516..9650)
                     /locus_tag="RPH49_001813"
     CDS             complement(9516..9650)
                     /locus_tag="RPH49_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="delta-lysin family phenol-soluble modulin"
                     /protein_id="HDY5124954.1"
                     /translation="MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
                     "
     gene            9886..10455
                     /gene="agrB"
                     /locus_tag="RPH49_001814"
     CDS             9886..10455
                     /gene="agrB"
                     /locus_tag="RPH49_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator AgrB"
                     /protein_id="HDY5124955.1"
                     /translation="MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQVLAKNIGKLI
                     VMYTLAYILNIFLFTLITNLTFYLIRRHAHGAHAPSSFWCYVESILLFILLPLVIVNF
                     HINPLIMIILTVISLGIISVYAPAATKKKPIPVRLIKRKKYYAIIVSLTFFIITLIIK
                     EPFAQFIQLGIIIEAITLLPIFFIKEDLK"
     gene            10452..10592
                     /locus_tag="RPH49_001815"
     CDS             10452..10592
                     /locus_tag="RPH49_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic lactone autoinducer peptide"
                     /protein_id="HDY5124956.1"
                     /translation="MNTLFNLFFDFITGILKNIGNIAAYSTCDFIMDEVEVPKELTQL
                     HE"
     gene            10617..11909
                     /locus_tag="RPH49_001816"
     CDS             10617..11909
                     /locus_tag="RPH49_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001670396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDY5124957.1"
                     /translation="MELLNSYNFVLFVLTQMILMFTIPAIISGIKYSKLDYFFIIVIS
                     TLSLFLFKMFDSASLIILTSFIIIMYFVKIKWYSILLIMTSQIILYCANYMYIVIYAY
                     ITKISDSIFVIFPSFFVVYVTISILFSYIINRVLKKISTPYLILNKGFLIVISTILLL
                     TFSLFFFYSQINSDEAKVIRQYSFIFIGITIFLSILTFVISQFLLKEMKYKRNQEEIE
                     TYYEYTLKIEAINNEMRKFRHDYVNILTTLSEFIREDDMPGLRDYFNKNIVPMKDNLQ
                     MNAIKLNGIENLKVREIKGLITAKILRAQEMNIPISIEIPDEVSSINLNMIDLSRSIG
                     IILDNAIEASTEIDDPIIRVAFIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEG
                     RGLGLSTLKEIADNADNVLLDTIIENGFFIQKVEIINN"
     gene            11928..12644
                     /locus_tag="RPH49_001817"
     CDS             11928..12644
                     /locus_tag="RPH49_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5124958.1"
                     /translation="MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVL
                     EQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDPVGNIIFVTSHSELTYLTFVYKV
                     AAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
                     FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKER
                     IVYFKNKEHCYASVRNVKKI"
     gene            12716..12823
                     /locus_tag="RPH49_001818"
     CDS             12716..12823
                     /locus_tag="RPH49_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124959.1"
                     /translation="MHCIAGFLILIAKLNMTRELKNDVTSLCIPIPITT"
     gene            complement(13012..13971)
                     /locus_tag="RPH49_001819"
     CDS             complement(13012..13971)
                     /locus_tag="RPH49_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDY5124960.1"
                     /translation="MRRLFSIGEALIDFIPNITNANLKDVQTFTKQIGGAPCNVACTV
                     QKLGQQAYMITQLGNDAFGDSIIETISSIGVDVSKVYRTNEANTALAFVSLTEAGERD
                     FSFYRKPSADMLFEPSFVNDIDVNENDVVHFCSVDLIDSPMREAHYQLITKTLNANGT
                     VVFDPNVRLPLWDNAEDLRQTIHTFLPLAHIVKVSDEELEFITGIHDENKAIQSLFTG
                     NVTVVIYTKGADGAAVYLKNGINHYHSGYKVKPVDTTGAGDAFIGAVISRILATDVLN
                     LTQLFENEGEEILAFSNRVAAIVTTKYGAINSLPTLQEVEQAF"
     gene            complement(13968..15452)
                     /locus_tag="RPH49_001820"
     CDS             complement(13968..15452)
                     /locus_tag="RPH49_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDY5124961.1"
                     /translation="MTEWTREERYQRIEDVDTEYFKTLKQQVDQSKFRQQFHIQPETG
                     LLNDPNGLIFYKGKYYVSHQWFPLGAVHGLKYWYNYTSDDLINFKAEGPILNPDTKYD
                     SHGVYSGSAFEFNGHLYYMYTGNHRDNHWQRHASQMIARLKEDGSVEKFPKPVISQQP
                     EGYTSHFRDPKVFKYGEKYYAIIGAQNNDQQGRLLLYNTEDIINWHYLGEINTELDDF
                     GYMWECPDYFNVDNQDVILICPQGIEPKGDQFKNIYQSGYILGKFDIEKLTYEHENFV
                     ELDNGFDFYAPQTFLDEKGRRVLIGWMGLPEIEYPTDNEGWAHCLTIPRVLNVENGQL
                     KQRPYPALEKLRHNKETALGYANKFTRKLHPYEGKQYELIIDILDNDATEVYFELRTS
                     KTSSTLIAYNKRENKIILDRSDSGLLPTNVEGTTRSTILETPLKQLQIFVDTSSIEIF
                     CNDGERVLTSRIFPTEDALGIKTSTESGQVYLQFTKYDLKDEHK"
     gene            complement(15601..16551)
                     /locus_tag="RPH49_001821"
     CDS             complement(15601..16551)
                     /locus_tag="RPH49_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDY5124962.1"
                     /translation="MKNISDIAKLAGVSKSTVSRFLNNGSVSKKTSEKLTKIIAEHDY
                     QPNQFAQSLRARQTHLIGAIIPRMNSYAVDETIKGLAKQCQKYESQLILNYTGLNIEA
                     EIQALETLARSKVDGIVLMATDITERHIEVINKMNVPIVIVGQQHEQLHSIVHDDYKA
                     GQIIGEWIGQQGYQQIEVFSVSEKDIAVGIHRKRGLLDQLAKYQIKPNIHETNFTYVE
                     AQKDVANVLENVEQVDAVVGATDTIALAAYKYYSDKKEVMKPHQIYGFGGDPMTQLVS
                     PSIKTIHYNYFEAGQCAMEEIQQMLKKQDMPYSVTVDVNI"
     gene            complement(16734..17984)
                     /locus_tag="RPH49_001822"
     CDS             complement(16734..17984)
                     /locus_tag="RPH49_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDY5124963.1"
                     /translation="MNLNDTIFMFLCTLLVWLMTPGLSLFYGGLVQSKNALNTVMQSM
                     AAIVLVTFVWITVGFTISFGEGNLWFGNWEYTFLNHVGFATQEDISPHIPFALFMLFQ
                     MMFCTIAISILSGSIAEKMKFIPYLLFVVIWTALVYSPVAHWVWGGGWINKLGVLDFA
                     GGTVVHITSGVSGLVLAIMIGKGNKHSESTPHNLIITLIGGIFVWIGWYGFNVGSAFT
                     FDQIAMLAFTNTVISASAGAIGWLILEYIFKKTTSLLGLLLGALAGLVVITPAAGYVT
                     YLSATIMALIGGICCYIVINYIKVKLKYHDALDAFGIHGVGGIIGAVLTAVFQSKKAN
                     PDIENGFIYTGDIHIILVQILCVTAVVIFSIVMTFIIAKVIKLITPLSVTEQETNIGL
                     DKIVHGEHAYFEGELNRFNKHIRY"
     gene            complement(18192..18416)
                     /locus_tag="RPH49_001823"
     CDS             complement(18192..18416)
                     /locus_tag="RPH49_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HDY5124964.1"
                     /translation="MIHELGTVGMVCPFPLIEAQKKMATLQSGDELKIDFDCTQATEA
                     IPNWAAENGYPVTNYEQIDNASWTITIQKV"
     gene            complement(18481..19557)
                     /locus_tag="RPH49_001824"
     CDS             complement(18481..19557)
                     /locus_tag="RPH49_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeeE/YedE family protein"
                     /protein_id="HDY5124965.1"
                     /translation="MMWMIFSGLIVGGLLGFVMQRTRFCLTGGFRDMYVQKNNKMFYA
                     LLIAITIQSIGLLILTATDILQIPAHSFPILGTIIGSFIFGIGIVLAGGCATGTWYRA
                     GEGLIGSWIALVLYAVTAAITKTGILKPVMDKINQPTNVNSDMSQTTGIPFWGLVVIL
                     TIITIFLVVRTLNNKKVRVAVPKLKQRYTGIRYYLFEKRYHPFIAAIAIGLIALLAWP
                     MSASTGRNDGLGITTPSANLVHFLITGETKFIDWGVFLVLGIFIGSYIAARGSREFKW
                     RLPDKITIRNSAIGGICMGFGASVAGGCSIGNGLVETATMTWQGWIALASMIVGVWTM
                     SHFIFVRPMKKYNNNLQRSNSKRK"
     gene            complement(19858..20493)
                     /locus_tag="RPH49_001825"
     CDS             complement(19858..20493)
                     /locus_tag="RPH49_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDY5124966.1"
                     /translation="MSDQVKIPRATLKRLPLYYRFVSSLKSKGIDRVNSKAISDALQI
                     DSATIRRDFSYFGELGKKGYGYNIDSLLDFFKSELSESDMIKIAIVGVGNLGKALLTY
                     NFSIHDDMTITEAFDVKEDVIGQKIGNVIVKDNDELITTLKKEEIDVVILTTPERVAQ
                     KVADELVQAGVKGILNFTPGRINTPSDVQVHQIDLGIELQSLLFFMKNYSE"
     gene            20746..22674
                     /gene="abc-f"
                     /locus_tag="RPH49_001826"
     CDS             20746..22674
                     /gene="abc-f"
                     /locus_tag="RPH49_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein"
                     /protein_id="HDY5124967.1"
                     /translation="MILLQLNHISKSFDGEDIFTDVDFEVKTGERIGIVGRNGAGKST
                     LMKIIAGVENYDSGNVSKIKNLKLGYLTQQMTLNSNATVFEEMSKPFEHIKRMESLIK
                     EETDWLSKHANDYDSDTYKTHMSRYESLSNQFEQLEGYQYESKIKTVLHGLNFSEEDF
                     NKPINDFSGGQKTRLSLAQMLLNEPDLLLLDEPTNHLDLETTKWLEDYLRYFKGAIVI
                     ISHDRYFLDKIVTQIYDVALGDVKRYVGNYEKFIQQRDLYYQKRMQEYESQQAEIKRL
                     ETFVEKNITRASTSGMAKSRRKILEKMERIDKPMLDAKSANIQFGFDRNTGNDVMHVK
                     NLEIGYQTAITKPISIEVSKGDHIAIIGPNGIGKSTLIKTIANQQKALNGDITFGANL
                     QIGYYDQKQAEFKSSKTILDYVWDQYPLMNEKDIRAVLGRFLFVQDDVKKIINDLSGG
                     EKARLQLALLMLQRDNVLILDEPTNHLDIDSKEMLEQALQHFEGTILFVSHDRYFINQ
                     LANKVFDLTIDGGKMYLGDYQYYIEKVEEAEALKAHQEEQSVNVQAHKKSMEQSSYHN
                     QKEQRREQRKLERQISECENEIETLETTILQIDEQLTQPEVYNNPQKANELAIQKQDS
                     EQKLEHAMSKWEELQQKL"
     gene            complement(22834..22947)
                     /locus_tag="RPH49_001827"
     CDS             complement(22834..22947)
                     /locus_tag="RPH49_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124968.1"
                     /translation="MVKTMSIENMRTYQQRVYNLWIKSVDKGIYCGYQVGK"
BASE COUNT         7755 a         3926 c         3374 g         7986 t
ORIGIN      
        1 ataactttcc aagttattca tgacacttaa ctcaagttga taaaccacgt gttctattac
       61 ttctttttgt tcattattca ttttctaatc ctcctgttaa attacatcct aaagttatta
      121 gccaagcata aacgctaaaa gcaacataca tgttagatat tgctagtaat aagattgtta
      181 acaacgaaac taagcagata taagttaagt agattttcat tgccttgcct ccaataactt
      241 tttgatattg acttgtttaa agtcgttatt ctggatattc atatgagcag taagctgttc
      301 catgaattca tctacatcag actttttgaa tctatacgta gatccgacca tataatattt
      361 catgccatta ttaataagta attcttcaat agtaggctta cttaaattca gatagttaga
      421 caactctttg taagtcataa aatatttctc tttcgctaat tcgtccacac gtgcattgat
      481 agcctgctca agtaactcac gtgcttcatc ttcatcaata ttaatgttga acattggttt
      541 atgcctcctt tacttcaaat tcaaataatt catttacctc aacttgtaaa acttctgcca
      601 ttttcttagc taatttaggg cttggaatct ttttaccatt aataatttgg cttaaataag
      661 aaattccaac acctgtttca cgtgataaat cagataaatt aaagcctttt aagaacatgc
      721 cttctttaaa ctttctagta ttcgctaaaa tagtcataat taaaatcctc cttcgttttt
      781 gactgacttc tcaatcaatt tataacttta ttatacataa tcgtttttct tttgcaatag
      841 tttttcgact gacttctcaa tcatttttta tttttttgta cataaacgtc caaaaaaatg
      901 ctattattaa cataattagg aggtttgtaa tgattagaaa tagattgtct gaactactgt
      961 cagaaagagg actaaaaata tctcgtgttg caaaagatgt aaaaatagca agaagttcac
     1021 ttacttcaat ggcacaaaat gattctgaaa tgataagata tgatgctata gataaattat
     1081 gtagttatct gcacatatct ccttcagaat tttttgaaca taatccgatc aattttgact
     1141 ttacttttga tgaagaaccg aattataaaa ttaatgatgt tttcgaggga tttgaagtaa
     1201 ctgcaaacat tactcacgct ttttcgattg aaaattttga ctttgaaatt ttagtagacg
     1261 tcgaattaga taataggcaa aaattaaatt ttgacttaga cgtctcatat aaagaaactg
     1321 aaaagataac taattcacaa catagattta ttttcacgat taaaaatgaa gatgaaaata
     1381 tcggattaaa aaaatacgtt gatagtttat ctgcaggcct taaaaacttg ttatttaaaa
     1441 aaattaacca aaagttaagt gggtatgttt ctgaaataat agtaaaaaat atagacgata
     1501 ttgaagagct ttttccaaat aaaggcgaaa aaagtacgac tctacataaa gaaattttac
     1561 aaactgatag ccgtttatct agtgatattt ttaaagaata ttaatcgagg tgatcaaatg
     1621 gcaagttatg aaaaacgcgg aaatacatgg cgctatcgta tatcactagg aaaagacgca
     1681 gaaacgggca aatataaata tatttcaaac tcaggtttta aacgcaaatc agacgctaaa
     1741 catcacgctg aaatggttga gcgtcaatta agaaatggcg attatatcgc accgtccaca
     1801 tctacattta aacaggtggc tgacgattgg atatcacaat atgctaacga agtaaaagta
     1861 agtagtgtca gagcacgcga gaaagccata aaccacgcca tagaacgctt taacaataaa
     1921 ccaatacaaa ctatcaataa acatgaatat caacgttttg taaacgatat aagcgcacag
     1981 tatagcaaga attatgttga tagcattata gcctctacaa atatgatatt taagtacgca
     2041 tacgatatga aattaataag aataatgcct agcgagggta ttaaacgacc taaaaagaaa
     2101 attagtgtgg aagaattaga agatactgag atacataaaa agtttcttga aaaagatgaa
     2161 ttatttcaat tcctggaggt tgctaaaaat caccattcac cccaaaacag ctttgaggtg
     2221 ttttgtacat tagcatatac aggcatgcgt gcaggtgaat tattggcatt gaaatggtct
     2281 gatatagact ttgagaataa cacaatcaat attacaaaga cttattacaa tccgaataac
     2341 aataaaaagc aatttcaaat acttacacca aaaactgaaa gctcaatcgg aaaaatttca
     2401 gttgatcctc atgtgattaa attacttaaa aactataaag tggatgttca ggatacatgg
     2461 aaaaacgaat tgtatgtaga taataatttc gtttttactg atgttaacgg ctatcccctc
     2521 gtaattaaga aactacaatt atggataaaa gctatactta aaaagactga cataactaat
     2581 aagcaaataa gcactcattc atttcgtcat actcattgtg cgttacttat agaggctggt
     2641 gttcatatta aggaaataca agaacgcttg cgccataagg atataaatac cactatgaac
     2701 atctacgcta agattacgaa ctcatacaaa aaagacgctt cccaaaagtt tagtaaactc
     2761 atggaaaacg tctcaaaaga tttattttaa aatttctatg accaaattat gaccacccaa
     2821 tattacaaac gttataaaat cagcgttcaa cagtcttttt acatcattcc cggcatgcca
     2881 cccatgttag gttggtcatt atttttttct ggaattgatg ctacaaccgc ttcagtcgtt
     2941 aagaacattg ctgcaacact tgctgcatgt tgtaatgctg agcgtgttac tttagttgga
     3001 tcaacgatac ctgcttctaa catattaacc cactcgtttg tagcagcgtt aaaaccaaca
     3061 cccggctctg cgtttttcaa acgttctaca ataacagaac cttctaatcc tgcattttca
     3121 gcaatttgac gaactggtgc agttagtgct ttaagtacaa tatttacacc tgtttcaatg
     3181 tcaccttctg cttcaatttc acttactttt tggtaaacat ttactaatgc agtaccacca
     3241 cctgcaacaa taccttcttc aactgctgca cgtgtagaat ttaatgcatc ttcaatacgt
     3301 aatttacgtt ctttaagctc tgtttcactt gctgcaccta ctttaataac tgcaacacca
     3361 cctgctaatt tagctaagcg ctcttgtaat ttttcacgat caaagtcaga ttcagtttct
     3421 tcaatttgag atttcaattg gcttacgcgt gaatcaatgc tgttttcgtc accgtcacca
     3481 tcaacaacag tggtattatc tttagttact tctactttac ttgcagtacc taacatatca
     3541 attgatgcat cttttaaatc taagcctaaa tcatcagtaa tcacttgcgc accagttaaa
     3601 atagctaaat cttctaacat tgctttacga cgatcaccga aaccaggcgc ctttactgca
     3661 acagctgtaa atgtgccacg catacggttt agcacgatat ttgttaatgc atcgccttca
     3721 acttcatcag ctacaattaa gattggacga ttagattgaa ccacttgttc taataaaggt
     3781 aagatatctt ggaaagacga gattttctta tctgtcacta aaatatatgg gcgttctaat
     3841 tcagcgacca ttttatctga atcagtaacc atatacggtg attgataacc acgatcaaat
     3901 tgcatacctt caaccacttc aagttctgta ttcaagccat ttgactcttc aattgtaatg
     3961 acaccatcat tacctacttt ttccatagct tcagaaatat aacgtccaat ttcttcatct
     4021 gctgcagaaa ttgcacctac ttgcgcaatt tcatttttat tttcaacttt ttgagaattt
     4081 tcatgtaacg cttcaacagc aactttaact gctttgtcga taccttgtcg taaaccaact
     4141 gggttcgcac cacttgtaac atttttcaag ccttcttgaa tcattgcttg agctaatact
     4201 gttgcagttg tcgtaccgtc accagcaatt tcatttgtct tatttgcgac ttcttgaact
     4261 agtttagccc ccatattttc atatggatct tctaattcga tttctttagc aatcgttaca
     4321 ccatcgttcg taattaaagg tgctgtaaac tctttatcta atacaacatt acgtccttta
     4381 ggaccaatcg ttactttaac tgcatttgca agttggtcaa caccacgtaa cattgcttga
     4441 cgtgcatctt cagagaattt caattgttta accataaatg ataaacctcc atttgtttag
     4501 ttgtgtttca ttttcgttct ttttaattta tttatgaatt aagttctgta ttattcaata
     4561 actgctaaaa tatcttcttc atttaatacc agatatgttt cattatctcg tttaacttct
     4621 gtaccagcat attgttggaa cacgacacgg tccccttctt tcacttcagg agtcactctt
     4681 gtaccatcat ttaatagacg tccagttcct actgcaacga taacgccttc gtttgatttt
     4741 tctttagcac tatcagttaa aacaatacca cttttagttg tttgttcttg ttcttttttc
     4801 tcaataatca cacgatttcc aattggtttt agcatgattg ttcctcctta aaaaaaccta
     4861 aagtttagca cttaacatta aagagtgcta acatacattt ataataatca aatttggtca
     4921 aaatttcaag tcataacctt ttaattaagt tttgtaactt caagttattt aagataaaat
     4981 aagttataaa taaaatatgt ggaggaaaat tatgacaaga ctatgggcat cattgctaac
     5041 tgttattata tatttattgt cgcaattttt accggcagtc attgtaaaca caacacaatt
     5101 tgcacaatat agtgatttgg aacaacttaa agccggcatc tatattcaac tcgttctatt
     5161 tttaattgcg gctactacga ttatttttat taattttaaa atcaaagacc ctacaagatt
     5221 agaatctgaa gtaaaggaac ctaataaata cattattcca tgggcattac ttggatttgc
     5281 acttgtcatg gtttatcaat ttatagtgag cattgtatta acgcaaattt atggtggaca
     5341 acaagtaagt cctaatacag aaaagataat tattattgct cgaaaaatac ctatatttat
     5401 cttctttgta tctattattg gtcctttatt agaagaatat gtattcagaa aagtaatctt
     5461 tggagaatta tttaatgcga ttaaaggtag tcgtatcgtg gcatttatta ttgctacaac
     5521 agtaagttca ttaatatttg cattagcaca taatgatttc aaatttattc cagtttattt
     5581 tggtatgggt gtcatttttt cattagcata tgtttggaca aaacggattg ctgttccaat
     5641 tattatccat atgttacaaa acggatttgt cgttatattc caattactta atcctgaggc
     5701 tttgaaaaaa gccacggaac aagcgaattt tatatatcac atttttattc cataataaaa
     5761 aaaacgaatc acacacggat tatcgtcgct gtgattcgtt tttatttttc tttttatttc
     5821 gctttacaaa taagaatagc atgattgaaa ataccaccat catagaacat acaattgcta
     5881 gccaactttt actatatgca gttgacgcac ttttcttatt atcttcttgt tttttaacta
     5941 ctgtaaaatc gtctttttca tgcggttcaa atgaacggtg ttttgaatcc ggcttatctt
     6001 cgggcttttt caaatctggc attgatccaa tttcaccagt aattaatgcg agtacctgtt
     6061 catctaaatt acgataatat cgttctgatt ttaaaggatt aaaatattgg aacctaaaat
     6121 agtttgattg ttgttgtaat ccatttaaat atgcatttcc gctgaagttt tgttttcgaa
     6181 taatattata aatgtcttca tcagtaactt ctccataatc tttgcccaac ttattaattt
     6241 gatttaaaat atacggatta tacttgtaag ccccattcgc caaggctaaa aatcgttggg
     6301 atacaaaatc attaccagta gtattttgtg agtttccttg atttccattt ggttgccatt
     6361 gaccttgatt agatccatct gaagcatttg ggttccatgt tcccccattt ttcgagccac
     6421 cagaatgatt ggaatcccca ggttgatcgg gatctggtga cgggttagga tttggcttat
     6481 tagggtctgg ttttggattc ggatttggct ttggtttatc tggatctggt tttggatctg
     6541 gatttggctt tggtttatct gggtctggtt ttggatctgg atttggtttc gggttatctg
     6601 gatctggttt tggatccgga tttggctttg gtttatctgg gtctggtttt ggatccggtt
     6661 ttggtttcgg gttatctgga tttggttttg gattcggact tgggttttgg ttatttgagt
     6721 ctggttttga atctggactt gggttttggt tgtttgagtc tggcttcaca ttattcgaat
     6781 caggattagc atcacgacta ttcgaacctg tttcttcatt acccgtttga tttgatttgt
     6841 gaggtgtccc agtctcatta ttattcattt cactatttac tgatggtgaa gttatattat
     6901 gattcaaatt agtagttggc ttttctccat ttaagttatc ctttgcttca actgtgtgcg
     6961 ttgcaagccc taaactacta ctacttaaaa ttaaaatact tgttgaaagt aacattttct
     7021 taaaccaatg atatgacatt tcacgagaca cctccctttt tcatgtaagt attaatctaa
     7081 gtataatcaa tatgcgttga aaatgcattt atatttggaa tttgaaaatg aatattaata
     7141 ttcttgaaat tttcgtaaat attactttgc aagttcgagt ataaatttta tacttagtct
     7201 attaagtatt ctttactaaa gaaggagcaa taattatggg tttatttaaa aaagataaaa
     7261 aagcaatgac ttttgacaat gcaatggaag aaagacgttc aatatataat ttgaaagatt
     7321 cgatatcaat tagcgatgac gaattagaat caatgattgc acatgcagtt aaacatgttc
     7381 cttcatcatt taattctcaa tcaactagaa ttgttctctt gttaaatgac aacaataata
     7441 aattttggga taacacaaaa gcaattttaa aagaagtcat gggagagaat cgtgatttcg
     7501 agccaactga acaaaaaatt gataacttca aacattcata cggcacaatt ttgttttatg
     7561 aagatcaaga tgttgtaagt ggtttacaag aacaaatgcc aaactactat gataattttg
     7621 caatatggtc aactcaaaca aatgccatgc atcaatttgc aatttggact gcattagcta
     7681 ctaaaggcat aggtgcttca ttacaacact ataatccact tgttgatgag atgacttcaa
     7741 atgaatttaa tattcctaaa agttggaaac ttattgctca aatgccattt ggtgatattc
     7801 gtgaagctgc tggtgaaaaa acatttaatc cagtggaaga tcgtttcgta ataaaaaaat
     7861 aatcaatatt ttgttaggaa tggtacagaa atgataaaga atcattagtt atccattatg
     7921 tagtagttct tacacattag ccgctgctaa tgtgcactta agaataggaa tacatgagta
     7981 aaactcatgt ataagaaata ctaatttcta aagaaaaagt atttctttat gttagagcct
     8041 aggactttga ttttatgtcc tgggctcgtt ttttgcgttt caacataact tttagtaagt
     8101 tatatataag atctatcaag gatgtgatgt tatgaaagtc caaatttatc aattaccgat
     8161 tatttttgga gatagttcta aaaatgaaat tcaaataacg caatggttcg aaaaaaatat
     8221 gaatgctgaa gtagatgtag tcgttttacc tgaaatgtgg aataatggct atgatttaga
     8281 gcatttaaat gaaaaagcag ataataatct aggacaaagt ttttcattta ttaaacattt
     8341 agctgaaaaa tataaagtcg atatcgtagc tgggtcagtt tctaacatta gaaacaatca
     8401 aatatttaat acagctttta gtgtgaataa aagtggccag ctgattaatg aatacgacaa
     8461 agttcattta gttcctatgt taagagagca tgaattttta accgctggcg aaaacgtagc
     8521 tgaacctttt caattgtcta acggtactta tgtgacccaa cttatctgtt atgatttacg
     8581 ttttccagaa ttattaagat atcctgctcg tagtggtgct aaaattgcat tttatgtggc
     8641 gcaatggcct atgtcacgtc ttcaacattg gcattcatta ctaaaggcac gtgcaattga
     8701 aaataatatg tttgtcattg gaactaatag cactggattc gatggtaaca cagaatatgc
     8761 tggtcattcg atagttataa atccaaacgg agatttagtt ggagaattaa atgaatccgc
     8821 agatattttg actgtagatt taaacttaaa tgaagtagaa cagcaacgcg aaaatatacc
     8881 tgtatttaaa agtattaaat tagatttgta taaataagaa gcgcctgaaa taatatttaa
     8941 cacatgtcat gactaaacat agatttatga gagatttttc ataagtctat gtttattttt
     9001 tataatagat aactcagtaa gaatccattt cgccctttgc aaatgaatga ttttcttaat
     9061 taaattgatt aattttttga ccttttccaa cattagactt atttatatat tttaacggtg
     9121 ggtctcataa tgaggattaa ctctcccctt ctttattaca ataaaaaagg ccgcgagctt
     9181 gggaggggct cacgaccata cttattatta agggaatgtt ttacagttat tttttcaatc
     9241 tatttttggg gatgttatta attatgaaaa aaattttatt tatcaaataa tgataaatcg
     9301 atgttgttta cgatagctta catgctagaa ataattatct gtaatgataa ttaagaaaaa
     9361 tacatagcac tgagtccaag gaaactaact ctactagcaa atgttactca cttgctaatt
     9421 ttacatggtt attaagttgg gatggcttaa taactcatac ttttagtact atacgaagat
     9481 aacaaattta caatgaaagt aattaattat tcatcttatt ttttagtgaa tttgttcact
     9541 gtgtcgataa tccattttac taagtcaccg attgttgaaa tgatatcttg tgccattgaa
     9601 atcactcctt ccttaattaa gataaaaatt cttaaaatta aacaactcat caactatttt
     9661 ccatcacatc tctgtgatct agttatatta aaacatgcta aaagcattta ttttccaatt
     9721 tttcttaact agtcgttttt tattcttaac tgtaaatttt tttatgttaa aatattaaat
     9781 acaaattaca tttaacagtt aagtatttat ttactacagt taggcaatat aatgataaaa
     9841 gattgtacta aatcgtataa tgacagtgag gagagtggtg taaaattgaa ttattttgat
     9901 aacaaaattg accagtttgc cacgtatctt caaaagagaa ataacttaga tcatattcaa
     9961 tttttgcaag tacgattagg gatgcaggtc ttagctaaaa atataggtaa attaattgtt
    10021 atgtatactc ttgcctatat tttaaacatt tttctgttta cgttaattac gaatttaaca
    10081 ttttacttaa taagaagaca tgcacatggt gcacatgcac cttcttcctt ttggtgttat
    10141 gtggaaagta ttttattatt tatactctta cctttagtaa tagtaaattt tcatattaat
    10201 ccattaatta tgattatttt aacagttatt tctttaggta taatctcagt atatgctcct
    10261 gcagcaacta aaaagaagcc cattcctgtg cgacttatta aacgaaaaaa atattatgcg
    10321 attattgtta gtttaacctt tttcattatc acacttatca tcaaagagcc atttgcccaa
    10381 ttcattcaat taggcatcat aatagaagct attacattat tacctatttt ctttattaag
    10441 gaggacttaa aatgaataca ttatttaact tattttttga ttttattact gggattttaa
    10501 aaaacattgg taacatcgca gcttatagta cttgtgactt cataatggat gaagttgaag
    10561 tacctaaaga attaactcaa ttacacgaat aataaaaata gaaagtgtga tagtaggtgg
    10621 aattattaaa tagttataat tttgttttat tcgtattaac tcaaatgata ttaatgttta
    10681 caataccagc tataattagt ggtattaagt acagtaaact tgattatttt ttcatcatag
    10741 taatttcgac attatcgtta tttctattta aaatgtttga tagcgcgtcc ttaatcatat
    10801 taacttcatt tattattata atgtattttg tcaaaatcaa atggtattct attttgttga
    10861 ttatgacttc gcagattatt ctgtactgtg ctaactacat gtatatagtt atatatgcat
    10921 atatcaccaa aatttctgat agtatatttg taatattccc tagctttttt gtagtttatg
    10981 tgactattag tatactattc tcatatataa taaatagagt tctcaaaaaa attagcacac
    11041 catatctaat actaaacaaa ggatttttaa tagttatttc gactatctta ctgcttactt
    11101 tttcattatt tttcttttat tcacaaataa actcggatga agctaaagta ataaggcagt
    11161 attcttttat ttttattggt atcactatat ttttaagtat attaacattt gttatttctc
    11221 aatttctcct taaagagatg aaatataaac gtaatcaaga agaaattgaa acctattatg
    11281 aatatacatt gaagattgaa gctatcaaca acgaaatgcg caagttccgt cacgattatg
    11341 tcaatatctt aacaacgctt tcagaattca ttcgagaaga tgacatgcct ggcctacgtg
    11401 attatttcaa taaaaatatt gtacctatga aagacaattt acaaatgaat gctataaaat
    11461 taaatggtat cgagaatctt aaagtacgtg aaattaaagg cttaattact gcgaaaattt
    11521 tacgtgcaca agaaatgaat attccgatta gtatagaaat acccgatgaa gtaagtagca
    11581 ttaacttgaa tatgatcgat ttaagtcgca gtattggtat tattcttgat aatgcaattg
    11641 aggcatcaac tgaaattgat gaccctatca ttcgcgttgc atttattgaa agtgaaaatt
    11701 cagtaacgtt tattgttatg aataaatgcg ctgatgatat accacgcatt catgaattgt
    11761 tccaagaaag tttttctact aaaggtgaag gtcgtggttt aggtctatca actttaaaag
    11821 aaattgctga taatgcagac aatgtcttat tagatacaat tatcgaaaat ggtttcttta
    11881 ttcaaaaagt tgaaattatt aacaactagc cataaggatg tgaatgtatg aaaattttca
    11941 tttgcgaaga cgatccaaaa caaagagaaa acatggttac cattattaaa aattatataa
    12001 tgatagaaga aaagcctatg gaaattgccc tcgcaactga taatccttat gaggtgcttg
    12061 agcaagctaa aaatatgaat gacataggct gttacttttt agatattcaa ctttcaactg
    12121 atattaatgg tatcaaatta ggcagtgaaa tccgtaagca tgacccagtt ggtaacatta
    12181 ttttcgttac gagtcatagt gaacttacgt atttaacatt tgtctacaaa gttgcagcga
    12241 tggattttat ttttaaagat gatccagcag aattaagaac acgtattata gattgtttag
    12301 aaactgcaca tacacgctta caattgttgt ctaaagataa tagcgttgaa acgattgaat
    12361 taaaacgtgg cagtaattca gtgtatgttc aatatgatga tattatgttt tttgaatcat
    12421 caacaaaatc tcacagactc attgcccatt tagataaccg tcaaattgaa ttttatggta
    12481 atttaaaaga actgagtcaa ttagatgatc gtttctttag atgtcataat agctttgtcg
    12541 tcaatcgcca taatatcgaa tctatagatt cgaaagagcg cattgtctat tttaaaaata
    12601 aagaacactg ctatgcatcg gtgagaaacg ttaaaaaaat ataataagat aataaagtca
    12661 gttaacggcg tattcaaatg taaatcttgt tggattttaa caagataact agcaaatgca
    12721 ctgtatagct ggctttttaa ttttaatagc aaaattaaat atgacgcgtg aattaaaaaa
    12781 tgatgtaacg tctctttgta tacctattcc tattactaca taatttatca atttctattt
    12841 cactctacaa tcctatagcg caatttttaa caaaatatac taaatttgaa atcgacagtt
    12901 ttcttaaata aaatactaca atttcctacc ccgtgaatct tatttttgtt ttaaaaaaca
    12961 gtgtagcaca agattcaact tgtttcctac actgttttat aaatgaatta tttaaaatgc
    13021 ttgttcaacc tcttgtaaag ttggcaaact attaatagca ccatacttcg ttgtcactat
    13081 tgcagcaacg cgattgctaa acgctaaaat ttcctcacct tcattttcaa ataactgagt
    13141 taaatttaac acatcggttg ctaaaatcct gctaataact gcgccaataa aggcatcccc
    13201 tgccccagtt gtatcaacag gttttacctt atagccacta tgataatgat taataccatt
    13261 tttcaaatat acggcagcac catctgctcc cttcgtataa atgactacag tgacattacc
    13321 tgtaaataat gattgaatgg ctttattttc atcatgaata cctgtaataa attctaattc
    13381 ttcatctgaa acttttacaa tatgcgccaa tggcaaaaag gtatgaatag tttgtcttaa
    13441 atcttcagcg ttatcccata atggcaatct tacattagga tcaaatacga cagtaccatt
    13501 tgcatttaat gttttggtaa tcaattgata atgtgcttct ctcatcggac tatcgatcaa
    13561 atcaacagaa caaaaatgta ctacatcatt ttcattcaca tcaatatcat tcacaaaact
    13621 tggttcaaat aacatatcag cagagggctt acgataaaaa gaaaaatctc gctcgcccgc
    13681 ttcagtcaaa ctcacaaaag ctaacgcagt gtttgcttca ttcgtgcgat acacttttga
    13741 tacatctaca ccaatacttg atatcgtttc aataatgcta tctccaaatg catcattacc
    13801 taattgtgta atcatatacg cttgttgtcc taacttttga actgtacaag ctacattgca
    13861 tggcgcgcca ccaatttgct tcgtaaatgt ttgaacatct tttaaattcg catttgtaat
    13921 atttggaata aaatcaatta acgcttctcc tattgaaaat agacgtctca tttatgttca
    13981 tcctttaaat catatttagt aaattgtaaa tatacttgcc ctgattctgt tgatgtttta
    14041 atacctagtg cgtcttctgt cgggaaaatt cgagatgtca aaacacgttc cccatcatta
    14101 cagaaaattt ctatactaga tgtatcaaca aaaatttgta attgctttaa tggcgtttct
    14161 aatatcgtac tacgcgtcgt accttcaaca tttgtaggca ataaaccact gtcgctgcga
    14221 tctaatatta ttttattttc acgcttgtta taagcgatta atgttgaaga agtcttagac
    14281 gtacgtaatt caaagtacac ttcggtagca tcattatcca aaatatctat gattaattca
    14341 tactgtttac cttcatacgg atgtaatttt cgagtaaatt tatttgcgta gcctaatgct
    14401 gtctctttat tatgacgtaa tttttccaac gctggatatg gacgttgctt aagttgacca
    14461 ttttctacat ttaatacacg aggaattgtt aagcaatggg cccatccttc attatcagta
    14521 ggatattcga tttccggtaa ccccatccat ccaattagta ctcgtcggcc tttttcatct
    14581 aaaaatgttt gaggtgcata gaaatcaaag ccattatcaa gctcgacaaa attttcatgt
    14641 tcatatgtta atttttcaat atcaaacttt ccaagtatat aaccactttg ataaatattt
    14701 ttgaactgat cgccttttgg ttcaatacct tgtggacaaa taagtatgac atcttgatta
    14761 tctacattaa agtaatctgg gcattcccac atatatccaa aatcatctaa ctctgtattt
    14821 atttcaccta aataatgcca attaattata tcttcagtat tataaagtaa taatcgacct
    14881 tgctgatcat tattttgtgc gccaatgatc gcataatatt tctcaccata tttaaaaact
    14941 ttaggatctc taaaatgact tgtatatcct tctggttgct ggctaattac tggctttgga
    15001 aacttttcta ctgaaccgtc ttctttcaat cgtgcgatca tctgactcgc atgtcgttgc
    15061 caatgattat ctcgatgatt tcctgtgtac atataatata aatgcccgtt aaattcaaaa
    15121 gcgctaccgc tataaacacc atggctgtca tatttagtat ctggatttaa aattggccct
    15181 tcagctttaa agtttattaa gtcatcactc gtgtagttat accaatactt taagccatgt
    15241 actgcgccta aagggaacca ttgatgtgaa acataatact tccctttata aaaaataagt
    15301 ccgttgggat catttaataa gcctgtttct ggttgtatat gaaattgttg acgaaatttt
    15361 gattgatcaa cttgttgttt taatgtttta aaatactcag tatcaacgtc ctcgattcgt
    15421 tgataacgtt cttctctagt ccattcggtc ataatattta cccagtcctc cttttataat
    15481 ttatgctgtt aacaatttat attctattat agcaaatttt acctacgttc tttaactttt
    15541 aacctatcca tttatagtta tatggtatcg gttccacatt tattttaaaa aatacagcgt
    15601 ctaaatatta acatctactg tgacgctata tggcatatct tgctttttaa gcatctgttg
    15661 tatctcttcc atcgcgcatt ggccagcttc aaaataatta taatgaattg tttttatcga
    15721 tggagacact aattgtgtca ttggatcacc accaaaacca tatatttgat gtggtttcat
    15781 aacttctttt ttatcagaat aatatttata ggcagctaat gcaatcgtat cagttgctcc
    15841 aacaaccgca tctacttgct ccacattttc caaaacattt gcaacatctt tttgtgcttc
    15901 cacataagta aaatttgttt catgtatatt aggtttaatt tggtatttag ctaactggtc
    15961 aagtaaacca cgttttctat gtataccaac tgcaatatct ttttcactca cactaaacac
    16021 ttcaatttgt tgatatccct gttgaccaat ccattcacct ataatttgac ctgctttata
    16081 atcatcatgc acaatactat gaagttgttc atgttgttga ccaacaataa cgattggtac
    16141 attcattttg ttaatgactt ctatatgtct ctctgttatg tctgtagcca ttaaaacaat
    16201 accatctact ttactgcgtg ctaatgtttc aagcgcttgt atttctgctt cgatatttaa
    16261 acctgtataa tttaaaatta attgtgattc atatttttgg cattgttttg ccaatccttt
    16321 gattgtttca tctactgcat atgaattcat tctaggtata atggcaccaa taaggtgtgt
    16381 ttgtctcgct cttaaacttt gagcaaattg attcggttga tagtcatgtt ctgctataat
    16441 ttttgttaat ttttcacttg tttttttact gacagatcca ttatttaaaa atctagatac
    16501 tgtacttttt gaaacgcctg ccaatttggc aatatcagat atatttttca tacttattca
    16561 cctatcatta tttgtgacac ttagccttat tttagcatat gtgtaaccgc tttaaataat
    16621 atttctgctt ctttcataaa aagatttcaa aataaaactt ttgtataaca aaatgtccca
    16681 acatcaacct ttagttaaat gtcaggacaa taaatattct atgtaaatat attctaatat
    16741 cgaatatgtt tattgaatct atttagctca ccttcaaagt aagcgtgttc accgtgaaca
    16801 atcttgtcta atcctatatt cgtttcttgt tccgtaacag ataatggtgt aattaattta
    16861 attactttcg caataataaa cgtcatgacg atactaaaaa ttacaactgc tgttacacat
    16921 aatatttgta caagtataat atgtatgtca ccagtataaa taaagccatt ctcaatgtca
    16981 ggatttgcct ttttactttg gaaaactgct gttaaaacag caccaataat accgccaaca
    17041 ccgtggatac caaatgcatc taatgcatca tgatacttta attttacctt gatgtaattg
    17101 atgacaatat aacaacagat acctcctatt aaagccatta ttgttgcact aagatatgtc
    17161 acgtatcctg ctgcaggtgt aatgacaact aaaccagcta atgcaccgag taaaagtcca
    17221 agtaaacttg tcgtcttttt aaaaatatat tctaaaatta accaacctat agcacctgca
    17281 ctggcagaaa taactgtatt cgtaaatgca agcattgcaa tttgatcaaa tgtaaaagca
    17341 ctgccaacat taaatccata ccaaccaatc cacacgaata taccgccaat caacgtaatg
    17401 ataagattat gtggtgttga ttcagaatgt ttgtttcctt ttccaatcat tatagctaat
    17461 actaaaccag aaacacctga tgtaatatga acaactgtac ctccagcgaa atctaataca
    17521 ccgagtttgt taatccaacc gccgccccaa acccaatgtg ctactggact gtatacaaga
    17581 gcagtccata ttactacgaa taataaataa ggaataaact tcattttctc agcgattgaa
    17641 ccagataaaa tagaaattgc aatcgtacaa aacatcattt gaaataacat aaacaaagcg
    17701 aaaggaatat gtgggctaat atcttcttgt gtcgcgaaac ctacatgatt aagaaatgta
    17761 tattcccaat ttccgaacca taaattccct tccccaaaac taattgtaaa accaactgtt
    17821 atccatacaa atgtaacaag cacaattgct gccatacttt gcatgacagt atttagcgca
    17881 tttttagatt gaactaaccc accataaaat aaacttaatc ctggtgtcat tagccaaact
    17941 aataatgtac acaaaaacat aaatatcgta tcgttaagat tcatacttac cactcccttg
    18001 ttttcataat aatctgacaa tttataaaaa gcaaaaatgc gttaagtttt attacatctt
    18061 ttggaataaa atatgccaca ctatataaaa ataatttcat gaactaaaac aaaaaagact
    18121 acttactcgc ttttaaacta gcggaagtag tcctaaactc taacatctat tttattgtta
    18181 aaatgataac gttaaacttt ttgaattgta attgtccatg aagcattatc aatttgttca
    18241 tagtttgtta caggatatcc attttctgct gcccaatttg gaatagcttc cgtcgcttgc
    18301 gtgcaatcaa aatcaatttt taattcatct ccagattgca atgttgccat tttcttttgc
    18361 gcttcaatta acggaaatgg acataccatt cctactgtac ctaattcgtg tatcataatt
    18421 atttctcctt ttccaatcac ttttatttga tcaacatcat ttgtataata atcttctata
    18481 ctatttgcgt ttgctgtttg acctttgcag attgttgttg tactttttca ttggacgaac
    18541 aaagataaaa tgactcattg tccatacacc aactatcatc gatgctagcg caatccatcc
    18601 ttgccaagtc atcgttgccg tttcaaccaa accgttaccg atagaacaac caccagcaac
    18661 tgacgcacca aatcccatac atatgccacc aatagcactg tttcgtattg taatcttgtc
    18721 tggcaatcgc catttaaatt ctcttgatcc tctagctgca atatatgaac caatgaaaat
    18781 ccctagaact aaaaagacac cccaatcaat aaatttagtt tcacctgtaa tcaaaaagtg
    18841 tactaaattt gctgatggcg ttgttatacc taaaccgtca tttcttccag ttgatgcact
    18901 cattggccaa gctaatagtg cgataagtcc aattgcaatt gctgcaataa atggatggta
    18961 tcgtttctcg aaaaggtaat atctaatacc tgtataacgt tgctttagtt ttggaacagc
    19021 tactcgaact ttcttattat tgagtgttct tacaactaga aaaatggtga ttatagttaa
    19081 tataacgact aatccccaaa acggaatgcc agttgtttga gacatatcac tatttacatt
    19141 cgttggttga ttaattttat ccattactgg ttttaaaatc cctgttttag tgattgctgc
    19201 agtaacagca tataatacta atgcaatcca actaccaatt aacccttcac cagcgcgata
    19261 ccaagtacct gttgcacacc ctccagccaa tactattcca attccaaaaa taaaagaacc
    19321 tataattgtt cccaatattg gaaaactatg tgcaggaatt tgtaaaatat ctgttgccgt
    19381 caaaatcaat aatcctatac tttgaatagt aatagcgatt aataatgcat agaacatctt
    19441 attattcttt tgcacataca tatctcgaaa gccacctgtt aaacaaaatc ttgttctttg
    19501 catgacaaaa cctaagagtc ccccgacaat taagccacta aaaatcatcc acataatcct
    19561 aacctctcat ttccgataag tttagtatgt attataggtg atgattttct tgttttcaac
    19621 cttatacaca atatttttga tatttatatt atattcatat aaggaaggcg attaattacg
    19681 attcatcatt atatctctac gtgttaattt attaacctat actatattta tcaacacaac
    19741 agtttttcct ttcattttca aacataacag aaaaagcctg agacatattt agtcccagac
    19801 tgctctataa ttaattaaag atataacaag gttaatcatt caaagctaac atcacattta
    19861 ttcactataa tttttcataa agaataataa tgactgtaat tctataccta agtcaatttg
    19921 atgtacttgc acatctgaag gcgtattaat tctaccagga gtgaagttta aaataccttt
    19981 cacaccagct tggacgagtt catctgcaac tttctgtgca actctttctg gtgtagttag
    20041 aatcacaaca tctatttctt ccttcttcaa tgttgttatt aattcatcgt tatcttttac
    20101 aataacgttc cctattttct ggccaataac atcttctttt acgtcaaacg cttctgtaat
    20161 cgtcatatcg tcatgtattg aaaagttata tgtgagcaaa gctttcccta ggttcccaac
    20221 tccgacaatt gcgattttga tcatgtcact ctcgcttagt tcagatttaa agaaatccaa
    20281 taaactatct atattatatc cgtacccttt tttacctaat tcgccaaaat atgaaaagtc
    20341 acgacgaatt gttgccgagt caatttgtaa cgcatcgcta atcgcttttg aatttacacg
    20401 atctatacct ttagatttta atgaactgac aaatctataa tataacggca aacgttttaa
    20461 agttgctcga ggaattttaa cttggtcact cattcgctat ttcctccttc gtgtttgaat
    20521 gaattatatc tatgtattca aacgagttag agcgtaattg ttagattatt aaaaaacaaa
    20581 taattgatta caatgaatac ctaaatatta tacattattg aattttaaaa ataaatatct
    20641 tagtttcaag acggcgtttt atactgtaaa atggttatta atgtaataat tacgactttt
    20701 ttcataagtt aataaaattt gagaaagacg aaaggtgaag atcgaatgat acttttacaa
    20761 ctcaatcata tatcaaaatc gttcgatggt gaagatatat ttactgatgt tgattttgaa
    20821 gtgaaaactg gcgaacgaat tggtatcgta ggaagaaatg gcgccggtaa atcaacattg
    20881 atgaaaatta tagctggcgt agaaaactat gattctggaa atgtgtcaaa aattaaaaac
    20941 ttaaaactag gttatttaac tcaacaaatg actttaaatt ctaatgcaac agtttttgaa
    21001 gaaatgtcaa aaccatttga acatattaaa cgaatggaaa gcttaatcaa agaagaaaca
    21061 gattggttat caaaacatgc aaatgattac gatagtgata catataaaac acatatgtcc
    21121 cgttatgaat ctttatcgaa tcaatttgaa caattagaag gatatcaata tgaaagtaaa
    21181 attaaaacag tacttcacgg gttaaatttt agtgaagaag atttcaataa acctatcaat
    21241 gattttagcg gtggccaaaa aacacgttta tctttagctc aaatgctatt aaatgaacct
    21301 gatttattac ttttagatga acctactaac cacttagatt tagaaacgac aaagtggctt
    21361 gaagattatc tacgttattt taaaggtgca atcgtcatca tcagccatga tcgttacttt
    21421 ttagataaaa tagttactca aatttatgat gtggctttag gtgatgtcaa acgctatgtt
    21481 ggtaattacg agaaatttat acagcaacgg gatttatact atcaaaaacg aatgcaagaa
    21541 tatgaaagcc aacaagcaga aataaaacga ttagaaactt ttgttgagaa aaatattaca
    21601 cgtgcttcaa caagtggaat ggcaaaaagt agacgtaaga ttttagaaaa aatggaacgc
    21661 attgataaac caatgttaga tgccaaaagt gcaaatattc aatttggctt tgaccggaat
    21721 acaggtaatg acgtcatgca tgtaaaaaat ttagaaatcg gttatcaaac tgcaattacc
    21781 aaacctatca gtatagaggt ctctaaaggc gatcatatag caatcattgg gccaaatggt
    21841 attggaaaat cgaccttaat taaaactatt gctaatcaac aaaaagcgct taatggcgat
    21901 attactttcg gcgcaaattt acaaattggt tattatgatc aaaaacaagc agaatttaaa
    21961 tctagtaaaa cgattttaga ttatgtgtgg gatcaatatc cgttaatgaa tgaaaaagat
    22021 attcgtgcag ttcttggacg tttcttattt gtacaagacg atgttaaaaa gataattaat
    22081 gatttatctg gtggtgaaaa agcacgttta caactagcac tacttatgtt gcagcgtgac
    22141 aatgtactta ttttagatga acctaccaac cacctcgata tagattcaaa agaaatgtta
    22201 gagcaagcac tccaacattt tgaaggaaca atactatttg tttcccatga tcgttacttt
    22261 attaaccaat tggcaaacaa ggtatttgat ttaacaattg atggcggaaa gatgtattta
    22321 ggagattatc aatattacat tgaaaaagtt gaggaagcgg aagcgttgaa agcgcaccaa
    22381 gaagaacagt cagttaacgt acaagcacat aaaaagtcta tggaacaatc gtcgtatcat
    22441 aaccaaaaag aacaaagacg tgaacaacgc aaacttgaac gacaaatatc cgagtgtgaa
    22501 aatgaaatag aaactttaga gactactatc ttacaaatag acgagcaatt aacccaacca
    22561 gaagtgtata acaatccaca aaaagcaaac gaattagcta tccaaaaaca agatagcgaa
    22621 caaaaattag aacacgctat gtctaaatgg gaagaattac aacaaaaact ataaaaatat
    22681 acataactct aactgtaaaa tcgctatagt tagagttatt tttttacaaa ttttaatttt
    22741 ttttattcac aataaaaacg ctgatattat agctatccac agacttatcc tagttatcca
    22801 caagtaaatt aacactaatc aatcatttat tttctatttc cccacctgat atccacaata
    22861 aatgccttta tcaacacttt ttatccacaa gttatacact ctttgttgat aagtacgcat
    22921 gttctctatt gacattgttt ttaccaaaat ccattgttaa gacattttct ttatgaaata
    22981 aggctgggac ataaatccct aaaaaaacag cagtaagata attttcaatt agaaaatatc
    23041 t
//
LOCUS       DAPSKH010000044        22711 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPSKH010000044 DAPSKH010000000
VERSION     DAPSKH010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22711
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.044"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..247
                     /locus_tag="RPH49_001828"
     CDS             <1..247
                     /locus_tag="RPH49_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124969.1"
                     /translation="NNRSEKGIIFWDNINSMGEKEFIEKVKFEKEEELLEKTIQQNYF
                     LAKTASMKYSIIRKVFIISALGYSCLLFSSIFQIICS"
     gene            286..1800
                     /locus_tag="RPH49_001829"
     CDS             286..1800
                     /locus_tag="RPH49_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017175164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDY5124970.1"
                     /translation="MATIGFEEKLWQAADKLRGSMDAAEYKNVALGIIFLKYVSDSFE
                     EKYEELLNDEYADEEDKDEYLAENIFWVPKESRWQYINDNSKKPEIGQIIDKAMIAIE
                     RENESLKGVLPKDYARPALDKEKLGDIIDLFTFKVGDSESKKQDILGRVYEYFIAKFA
                     SAEGKNAGEFYTPASIVKLLVEMIEPYQGRIYDPCCGSGGMFVQSEHFIERHQGRIDD
                     IAVYGQESNPTTWKLAKMNLAIRGIDNNLGDHHADTFHNDLHKDLKADFILANPPFNA
                     SDWGREKLQDDYRWKFGIPPKGNANYAWIEHMISKLAPSGTAGFVLANGSMSTSGKDE
                     LEIRKNLIEQDMVECIVTLPGQLFYSTQIPVCLWFMTKNKAKNGKNERRGEVLFIDAR
                     NIGSMVSRTLKEFSDDEIKDIANVYHSWRGTNNNQYEDKAGFCKVAKTEEIKNNEYIL
                     TPGRYVGLAEVEEDSEPFEQKMERITADLSEQFAKSKELEDQIRKSLEGLGYGV"
     gene            1790..3022
                     /locus_tag="RPH49_001830"
     CDS             1790..3022
                     /locus_tag="RPH49_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDY5124971.1"
                     /translation="MEFETFNLTDLYTISSGLSKNRKYFGTGTPFLTFKDVFDNLILP
                     NEFSGQVITEEKEREKYSVKKGDLFLTRTSEKQNELGISAVALKDYKNATFNGFTKRL
                     RPNKYCENKLLPVFAAFYFRSNNFRNQVNSMSIMSTRASLNNEMISKLKITIPSLQNQ
                     MKISHILLALLKKEKINQKIIANLEELSQTLFKRWFVDFEFPDENGNPYKSSGGEMVD
                     SELGEIPRSWKVDELGNYIKIKSGKRPKNKVDKEDIENVVPIIGASKIVGYTNDYLYN
                     EKIIIIGRVGTHGVIQRFSTRTWPSDNTFVITSDFESIIYQVLKSIDYISLNRGSTQP
                     LLSQKDIKNTKVVMPTNATLLSKYQKKNNHILKMMDQKIIENKKLTQLRDTLLPKLMS
                     GEIEIPDDIEVNEDDLSI"
     gene            3006..6134
                     /locus_tag="RPH49_001831"
     CDS             3006..6134
                     /locus_tag="RPH49_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDY5124972.1"
                     /translation="MIFQFSEDDLEQVALKWFEGLGYSVKNGRDSSDNGIMNERESDK
                     DVVLDDRLEAALRRINPELNNSAIEQAIHEISIEKSPSLLENNRSFHEMITNGIEVEH
                     YNDDGETINDLVYVLDFDNPGNNDFLAVNQLTVVNGDYKKRPDIVLFINGLPVVVIEL
                     KNSTNESVGIEDGYHQLETYKMRIPQLFNHNAVLVTSDGVNTKAGSLTADYDRFMTWR
                     TKDGKTEDSSTFRSLDILIHGMLNKEVLLDLIRHFVLFQDDGKGNIVKILAAYHQYYA
                     VNKAVDRAMEATSEHGDGKGGVIWHTQGSGKSLTMVFFSGKLIQKLNNPTLVVVTDRN
                     DLDNQLYGTFVKSKGRSGKGLLRQTPKQAESRKELKELLSVESGGIVFTTMQKFEPEE
                     GQVTMDALTERKNVVVMADEAHRTQYGFKATYNEKGEGIKYGYAKYLRDALPNASFVG
                     FTGTPVSSTDKNTQMVFGNYIDVYDMTQSVEDGSTVKIYYESRIIPLNLPTDLDIDDA
                     YDVITFGQEEDTKSRLKSKWSRIEALSGAEKRVHALATEIINHFETRQKAMNGKGMIV
                     TMSRRIAVDLYDEIIRLKPEWHSDDDDKGVIKVVMTGSSSDPQNFQKHIGPKKRRNLL
                     ENRMKDINDELQLVIVRDMWLTGFDVPSMHTMYIDKPMKGHNLMQAIARVNRVFKDKP
                     GGLIVDYVGIAESLKEALKEYTDSDREQTGIDTDKALELMLVKYDIIQDMLYNHDYSD
                     FESEDQLNRYNAISNTMDYIIGLGEKERERFVTTVTELSKAFALCATEEAAQELNSEI
                     AFLKAVKSGLVKLLAPPNEGSKLKKTPAEIEAEINQLISKSVVTEEVVDIYQTLGIEN
                     PDISILSDDFLKDVEGLQQKNVAVELLNKLLKGQVKSLMKTNTTVSKRFSEMLSKSIQ
                     KYNNRSIEASKVIEELIQMAKEINQEKERGKELGLSTEEIAFYDALASHETAKEAMDD
                     KELRAIAHELTKTVKNNMSVDWSKRESAKAKMRVQVRRLLKKYGYPPDIQKMAVEQVV
                     EQAELMASQQYK"
     gene            6247..6954
                     /locus_tag="RPH49_001832"
     CDS             6247..6954
                     /locus_tag="RPH49_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124973.1"
                     /translation="MKFDLIISNIMIGILVICSAFALMFVFYIQRKLTPEQYFSFSEF
                     FLIGRGLTIKKILNRMILIASFNCILFLILKNFFEIELVCSVCILSTLLGSILIIYPA
                     FKIRHDLPNNEMKSLLNYMYVSFVFLALIISTLTVFTLVVLFDDISIVTLWQEHKSGI
                     ILYLLLVIPSLFFNPTNYEKKMEYAIEKHRESNREINETIIKNNNETIIPDESKSSSP
                     FKIKKVFRLLNRIMKDD"
     gene            6947..7414
                     /locus_tag="RPH49_001833"
     CDS             6947..7414
                     /locus_tag="RPH49_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124974.1"
                     /translation="MIEYYLKKIIHLFENNKCEILHLKMNFNDNFDMLSYIYCIENMH
                     RGSNIIKIAEYILVKYFQKYCIKKDFSIGPFQVKKSFCVSNNLYLESLDKLLELHSSA
                     HVINEFIENKKYYLNNNEILSLYHSGKVMDTSFSTLMYIGLFKHFSSYLRKHE"
     gene            complement(7677..8234)
                     /locus_tag="RPH49_001834"
     CDS             complement(7677..8234)
                     /locus_tag="RPH49_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDY5124975.1"
                     /translation="MITTIVLTLCTFVSWLLIPHKITRYILGTLFTLALTLTIIGITA
                     NMTNHWGMEKKVITSNKKEIFTGGPKNNPANILIINEIGKNTNNYVMVYRDHPKDKKP
                     TTHFKPKMDKNNISESVKHQAKYEVKNTDKATQQTQKEVWVWKSDLYKSLLSFDESEN
                     ELIQSTTTVTVPKDTWVIINAKKDK"
     gene            complement(8236..9753)
                     /locus_tag="RPH49_001835"
     CDS             complement(8236..9753)
                     /locus_tag="RPH49_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDY5124976.1"
                     /translation="MSTQKSNAMNLDIHGNQYKPKIIMSIILLATFSGALMQTSLGTA
                     LPTLMNDFDIDFSTAQQATTWFLLANGIMVPLSAFLATRISTRLLHVYSYGALLFGLI
                     LTAIAPSNQDGWLIFLAGRIVTAIAVGLMMPLLQIIIIYMFPIKQRGTAMGLSGLAVG
                     LAPAMGPTFAGWILNKNHEVLGITISDSWRNIFVLPIIIIAIAFILSFFFMKDVIPNR
                     KLKLDLYSLILSCIGFGLFLWGFSNVASEGWGNINYVILPIFLSIIVLTLFVIKQLKS
                     KDPFLDLRVFKSKGFMIATIGLIVVTMAMYGVEMMLPTYLQNIHGFSPFESGLTLLAG
                     ALMLGFISPISGILYNKIGIKRLAFVGFTILTLASVPFGFLTVNTSPTLILVLYAVRM
                     FGVAILMMPLTTNAMDALPFEKGTHATAVNNTARQVASSIAVALLTSVTQNIINNHMP
                     ADSLKESNPLKYAHLAQQASIDGFNTAFIIGIFFAIIGIILVPFLKMNIIESEDK"
     gene            9901..10473
                     /locus_tag="RPH49_001836"
     CDS             9901..10473
                     /locus_tag="RPH49_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000540837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDY5124977.1"
                     /translation="MGYKRKTVLTQRNIKNALVSLLENNKFDFITINQIVEEAEITRS
                     TFYRYYDDKYELISEIEEEILEHIHKERQKIDENASEKNLLDIEMFKYLFETLEPYSN
                     TIYRLLGYNGDSSFEMKLKNEISRRFIDIEQRNHISQVRADLVKEYVFVIMIKTLQYW
                     SAHKDEVDIDEIALTIRDIQLKGLRKAIGL"
     gene            complement(10531..11517)
                     /locus_tag="RPH49_001837"
     CDS             complement(10531..11517)
                     /locus_tag="RPH49_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDY5124978.1"
                     /translation="MKENFWSELPRPFFILAPMEDVTDIVFRHVVSEAARPDVFFTEF
                     TNTESFCHPEGIHSVRGRLTFSEDEQPMVAHIWGDKPEQFRETSIQLAKMGFKGIDLN
                     MGCPVANVAKKGKGSGLILRPDVAAEIIQATKAGGLPVSVKTRLGYYEIDEWKDWLKH
                     VFEQDIANLSIHLRTRKEMSKVDAHWELIEAIRNLRDEIAPNTLLTINGDIPDRKTGL
                     ELAEKYGIDGVMIGRGIFHNPFAFEKEPREHTSKELLDLLRLHLSLFNKYEKDEIRQF
                     KSLRRFFKIYVRGIRGASELRHQLMNTQSIAEARALLDEFEAQMDEDVKIEL"
     gene            11826..12029
                     /locus_tag="RPH49_001838"
     CDS             11826..12029
                     /locus_tag="RPH49_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124979.1"
                     /translation="MEDLKHSLKSLGWWDLFFAIPMFLLFAYLPNYNFITIFLNIVII
                     IFFSIGLILTTHIIIDKIKSSTK"
     gene            12078..12374
                     /locus_tag="RPH49_001839"
     CDS             12078..12374
                     /locus_tag="RPH49_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
                     /protein_id="HDY5124980.1"
                     /translation="MATKKDVHDLFLNHVNSNAVKTRKMMGEYIIYYDGVVIGGLYDN
                     RLLVKATKSAQQKLQDNTLVSPYPGAKEMILIPDFDEATNLTDLFKTIKNDLKK"
     gene            complement(12438..13658)
                     /locus_tag="RPH49_001840"
     CDS             complement(12438..13658)
                     /locus_tag="RPH49_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5124981.1"
                     /translation="MTDLLKIKNFRLFFLAEIISAFGVGISTVGANWYLIDKTNDSQL
                     LGIMLALNVLSGFLASPIIGGLADKYNRRNIILITYLLQVILYLLIVIALVMIGFETY
                     LVIGFAIVNGIGWTTYMATSRSLVKQILKPDQYTDANSLLEISLQTGMFIAGGLSGIL
                     YEINGFTLIIAMTIMMFLISIFMLFRLHVDKPTHSEEESTNSLLQEYLLGWKFLKDNM
                     MIFIFGVISIIPMVFTMIFNISLPGYVYNVLKISSVQFGFSDMLYGIGGLCAGLISAI
                     LSKKISTKVLIFLLYFILVINSALFIWINSAFYLFIGSFILGYSISSIRIYMNTAIMN
                     TVSDKYVGRSFTIWTSISLLLQSFIAPFLGRWINEINDKFGFYIILILSLLIFVTLLI
                     VNKTDKIKYAHKEE"
     gene            complement(13651..14202)
                     /locus_tag="RPH49_001841"
     CDS             complement(13651..14202)
                     /locus_tag="RPH49_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDY5124982.1"
                     /translation="MITCLFGSSRKDGNSGIAVENLLKNLNVNFVNLYQSNIEKVTDN
                     RHSKGANFHNDDYEQILIKVLESDIIIFSTPLYWYSMSASLKLFIDRWTESLRDTQID
                     NFKEIMSQKKYLILIIGGDNPHTKAQPLVNQFKLIFEFMNITNYRFLIGEGNKPFDIL
                     NDSQFIEELANINLALKKGDIYD"
     gene            14315..15175
                     /locus_tag="RPH49_001842"
     CDS             14315..15175
                     /locus_tag="RPH49_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5124983.1"
                     /translation="MNLNILKSFLVTSETKNLTKASELLNYSQSTVSTHIEKLERQLD
                     VKLFYRKKYGMELTEEGLAYVKYAKVILDSNSEYEREIKGLYNKKVNISINMQESQYL
                     YRYYNKISEWLAEHPYVNLKFKSAHSNFYIKEEIANFKSDISLITDEKIINSNLTAIP
                     ITEERLIFVTNKEMKDFKLNDIQNHTLLVTEKGCSYREQLEKILYKYSFSTKQMIEFL
                     GIESLKKHLKNSDGIALLPEFIVADELQNKSLFQIDVDVDIPNLETTLIINPESSKQV
                     LESFVKDVFL"
     gene            complement(15529..16062)
                     /locus_tag="RPH49_001843"
     CDS             complement(15529..16062)
                     /locus_tag="RPH49_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4865 family protein"
                     /protein_id="HDY5124984.1"
                     /translation="MHAMQYHVKLPSDYNMEIIRDRVRLNGYKTDGFKNLIIKAYLIS
                     QTTSNCITNTYSPLYLWRSSEGMTEFIFNGFYDNVISSFGWQNINIGVIYSMNITDSV
                     KHSLYALEEYIDIFPTLSLKEIEIKKLFRIFDNAVAEIIIYNPDKWKFVKYSFIENLP
                     KSLNPNIKIYDVLYISQ"
     gene            16153..16896
                     /locus_tag="RPH49_001844"
     CDS             16153..16896
                     /locus_tag="RPH49_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5124985.1"
                     /translation="MIKLNFNDLEIFITVCEEASINKAAIKLRYAQSNISQRISKLEN
                     ELGVVLLFRNQKGAKATKAGEEFLAYSKKVLRDTETIKNKMKYNTMSILCSELLFNYL
                     SESEEIMMSNNSINFISSGNIRKAIEKNNYDKVISFIKINDSNYRLSNVDTMKVTLYS
                     NGSNYDKESLLINKDEFCPLRKITLDIKLDSQRVMEFDSLAAIINLVEQGKGKALLPM
                     TFENKRDIVQDISKIFEVSYYTYNHIMHH"
     gene            complement(17127..17546)
                     /locus_tag="RPH49_001845"
     CDS             complement(17127..17546)
                     /locus_tag="RPH49_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5124986.1"
                     /translation="MSKKYILIIIGTIFTIAFIIVGVILIMKYNELMKQKEFYYKQQQ
                     ERITLYLKHNTKEPNTIKSVHFTSLDKGPLDERIIEGYINNNKDDGFVAYMVPAYNHQ
                     FGGDMLRDETVQKLLKPSKDRKSPDQIKKELKEKRSK"
     gene            18090..18692
                     /locus_tag="RPH49_001846"
     CDS             18090..18692
                     /locus_tag="RPH49_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124987.1"
                     /translation="MLISLVIPVFALLVIGGIIWMIIEGIVHISKKNKAIDNFFNQVN
                     KVSETYKFATTFLFLILATAGISQFYLYYIVSAFLFWLVILTFGIAGIIFLMPYGLCF
                     LPFYKQKKKKQTFKKYMVYTTIGLSICLGLSLVLVHTTKIYMDEGGVRYYYGSFVMKQ
                     AGGYAYLALAVLSTLLIVAKKATNKNKEIETVDNTNITER"
     gene            18959..22111
                     /locus_tag="RPH49_001847"
     CDS             18959..22111
                     /locus_tag="RPH49_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA2/NAM7 family helicase"
                     /protein_id="HDY5124988.1"
                     /translation="MSQLLNDTLSAWLLIESLSPGEVNFTAEDILSAEHFKNGAKQAQ
                     LQSFDEYFEIWNAERFIISEEKSETGELIFKFYRHCFRYNEINLKIQDIFDDYSEIHN
                     PNGTHCYGYTFNTDKHGKVIVDSIHIPMIMSALKEIEKNKNANIEEKFNDSVEKFVQK
                     VKEILADEPINEFKLKKMDKAYDEYFSVLNSKKDGLFGHYVAIEYVKDSDLPQPEFNS
                     FFISDIEKARKSPNQTLIDYIEGVEESQRIEVDENKEMFDKFLHPSRLPDGRWPSQTE
                     FRLSLMQQLAVNQITSGNERISSVNGPPGTGKTTLLKDIFAHLVVERGKELAKLNNPK
                     DAFVKTKIHETDDKYVYLLKESIAKYKMVVASSNNGAVENISKDLPKIEEIIRNPEKC
                     KFPKYEQNYANLAHELKDFAEIAEDLIGESAWGLFSGVFGKSTNINQVLSHMLKQDAN
                     DIGFAKLLQNENNRMSYNELMSEWQSHQCAFLEELRHVEMLKEESIRAYDVYKNCESF
                     SKIEQVINSEKTSIEEQIYHLDNETLRDNKEIEDLGDRINYNTKQLETLNELIKSIKE
                     SNKGFINKLKAMFNSEEDESYKDHNKEKQQLLTQQLELEKCKKNKHEDLVSKLKEKEK
                     LIKQLTKVQLQLDELNSQLQELEAYRIESKITIPEKDFWSDNNYDERQVTNLWTSDEL
                     QYRRAMLFLRAMILHKLLLIANNTTIYYAINDFKDRRKLIDANPDKVHNAWNVMHLIF
                     PVVSTTFASFKSMYGGIPKDFIDYLFIDEAGQAIPQAAVGALYRSKKVVAVGDPIQIE
                     PVVTLESHLIDNIRKNYHVPEYLVSKEASVQSVADNANQYGFWKSDATDSNQKTWIGI
                     PLWVHRRCLKPMFTIANQIAYNNKMVLPSNITKVGKTGWYDVKGNAVQKQFVKEHGEK
                     VVGLLADDWIEAIKEGKNEPSSFVISPFSAVQQQIKRMLKQQLPTRIDIERTKINQWV
                     DKSIGTVHTFQGKEAQKVYFVIGTDNTQDGAVNWSCEKPNLLNVAVTRAKKEFYVIGD
                     MQRIQMKPFYETIFKERNVK"
     gene            22186..22668
                     /locus_tag="RPH49_001848"
     CDS             22186..22668
                     /locus_tag="RPH49_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124989.1"
                     /translation="MKKFNNWILNAISGSQTDKNETTEELKGAKFIILYAYSMLVLLA
                     LVISNIFIHILEPKLSITTQIIIVLILIETLIGLRFLKAYDVKRGKDKENKKNSKDFV
                     KLKSILVAILFTSLALTAGTVADIYGFTDLGNTRSDLIVWSIGGIIFGLVCYTMEDKK
                     "
BASE COUNT         8429 a         3031 c         3883 g         7368 t
ORIGIN      
        1 aaataataga agcgaaaaag gaattatttt ttgggataat ataaatagta tgggagaaaa
       61 agaatttata gagaaagtga aatttgaaaa agaggaagaa ttacttgaaa agacgataca
      121 acaaaattat tttttagcaa aaactgcatc tatgaaatat tcaatcatta gaaaggtttt
      181 tataatttca gcattaggtt attcctgttt attattttca agtatctttc agattatatg
      241 ctcttgaatt ttcagtttta acatgaaaag gagaaaaata aaaatatggc aacaattgga
      301 tttgaagaaa agttatggca agcggcggat aagttacgtg gaagtatgga tgcagcagaa
      361 tataaaaatg tagcattagg tattatattt ttaaaatatg tttctgattc ttttgaggaa
      421 aagtatgaag aattattaaa tgatgaatat gccgatgaag aagataaaga tgaatactta
      481 gcagaaaata ttttctgggt tcctaaagaa tcaagatggc aatacataaa tgataattct
      541 aagaaaccag aaattggtca aattatcgat aaagcaatga tagcaattga aagagaaaat
      601 gagtctttaa aaggcgtatt acctaaagat tacgcaagac ctgcattaga taaagaaaaa
      661 ttaggcgata ttattgacct atttacattc aaagttggag attctgaaag taagaagcaa
      721 gatattttag gtcgtgttta tgaatacttt atcgcaaaat ttgcaagcgc tgagggtaag
      781 aatgctgggg aattctatac accagcttca atagttaaat tgcttgttga aatgattgaa
      841 ccatatcaag gtagaattta tgacccttgt tgtgggtcgg gcggaatgtt tgtacagagt
      901 gaacatttta tcgaacgtca tcaaggtcgt atagatgata ttgctgttta tggtcaagaa
      961 tctaatccga ctacttggaa attagcgaaa atgaatttgg ctattcgagg tatagataat
     1021 aatttaggtg atcatcatgc agacacattt cataatgatt tacataaaga tttgaaagct
     1081 gattttatat tggctaatcc accattcaat gcaagtgatt ggggacgaga aaaattacaa
     1141 gatgattacc gctggaaatt tggtattcca cctaaaggca atgccaacta tgcatggatt
     1201 gaacatatga tttctaaact tgccccaagt ggtacagcag gatttgtttt agcgaatggt
     1261 tcgatgtcta caagtggtaa agatgaatta gaaatacgta aaaacttaat tgaacaagac
     1321 atggttgagt gtattgtcac attaccaggg caactattct attcaactca aattccagta
     1381 tgtttgtggt tcatgacaaa aaataaagct aaaaatggca agaatgaacg acgtggagaa
     1441 gtactattta tagatgctag aaatatagga agcatggtat caagaacatt aaaagaattc
     1501 tcagatgatg aaataaaaga tatagcaaat gtttatcact catggcgtgg aacaaacaat
     1561 aaccaatatg aagataaagc aggtttctgt aaagtagcaa agacagaaga aataaaaaac
     1621 aatgaatata tcttaacgcc gggacgttat gtaggattag cagaagtaga agaagactca
     1681 gaaccatttg aacagaaaat ggaaagaatc acagcagatt taagtgaaca atttgcgaaa
     1741 tcaaaagaac tcgaggacca aatccgtaag tcattggagg gattaggtta tggagtttga
     1801 aacatttaat ttaactgatt tatatactat tagttcaggt ttatcaaaaa atagaaaata
     1861 ttttggtact ggtacacctt ttttaacatt taaagatgta ttcgataatt taatattacc
     1921 taatgagttt tctgggcaag ttataactga agaaaaagaa agagaaaagt attcagttaa
     1981 aaaaggagac ctttttttaa caagaactag tgagaaacaa aatgagttag gtataagtgc
     2041 agtagcttta aaagactata aaaatgcgac ttttaatgga tttaccaaaa gattaagacc
     2101 aaacaaatat tgtgagaata aattgttacc agtatttgct gcattttatt ttagaagtaa
     2161 taattttaga aatcaagtaa attctatgtc tatcatgtct acaagagcaa gtttaaataa
     2221 cgaaatgatt tcaaaactta aaattactat acctagtctt caaaatcaga tgaaaattag
     2281 tcatatacta ttagcacttt taaaaaaaga aaaaatcaat caaaaaatca tagcaaatct
     2341 tgaagaactt tctcaaacac tattcaaacg ttggtttgtt gattttgaat ttcctgatga
     2401 aaatggaaat ccatacaaat caagcggtgg agagatggtt gatagtgaat tgggtgaaat
     2461 acctaggagt tggaaagttg atgaattagg aaattatata aaaataaaaa gtggtaaaag
     2521 acctaaaaat aaagttgata aagaagatat agaaaatgtg gtgccaataa ttggtgctag
     2581 taaaatagtg ggttatacga atgattattt atataatgaa aaaattatta taattggtag
     2641 ggtaggaact catggtgtaa tccaaaggtt ttctacaaga acatggccat cagataatac
     2701 ttttgtaata acaagtgatt ttgaaagcat tatatatcaa gtacttaaaa gtatagacta
     2761 tatatcattg aatagaggtt ctacacaacc tctattatct caaaaagata ttaagaatac
     2821 taaagtagta atgcccacca atgcaacttt gctttcaaaa tatcaaaaga aaaacaatca
     2881 tattttaaaa atgatggatc aaaaaatcat agaaaacaag aaattaaccc aactccgtga
     2941 cacattatta ccaaaattaa tgtcaggtga aattgagata cctgatgaca tcgaggtgaa
     3001 tgaagatgat ctttcaattt agtgaagatg atttagaaca ggttgcactg aagtggtttg
     3061 agggtcttgg ctattctgtt aagaatggtc gagatagtag tgacaatggg attatgaatg
     3121 aacgggagag cgacaaagat gttgtgcttg atgatcgttt ggaagcagct ttgagacgca
     3181 ttaatcctga actaaacaat agtgcaattg aacaggcaat tcatgaaatt tctattgaga
     3241 agtctcctag tttattagag aataatcgtt ctttccatga aatgattact aatggtatcg
     3301 aggttgaaca ctataatgat gatggtgaga cgattaatga tttggtctat gtgcttgact
     3361 ttgataaccc aggaaataat gatttcttag cggttaatca attaactgtt gtaaatggag
     3421 attataaaaa aagacctgat attgtgttat tcataaatgg attaccagta gtggtaattg
     3481 aactgaaaaa ttctacaaat gaatctgttg gtattgaaga cgggtatcat cagttagaaa
     3541 cttataaaat gagaattcca caattattta atcataatgc agtattagta acgagtgatg
     3601 gtgtcaatac aaaagctggt tctttaactg ctgattatga ccgttttatg acttggcgta
     3661 ctaaagatgg aaaaactgaa gattcatcaa cgtttcgtag tttagatata ttgattcacg
     3721 gtatgttaaa taaagaggta ctattagatt taattcgtca ttttgttttg ttccaagatg
     3781 atggtaaagg aaatatagtt aaaatattag ctgcatatca tcaatattat gcggttaata
     3841 aagctgttga tcgtgctatg gaagcaacat ctgaacatgg tgatggtaag ggcggcgtta
     3901 tttggcacac acaaggttct ggtaagagtt tgacaatggt cttcttctca ggaaagttaa
     3961 ttcaaaaatt aaataatcca acattagtgg tcgtaacaga ccgtaatgac ttagacaatc
     4021 aattatatgg tacttttgtt aagtccaaag gacgctcagg taaaggatta ctaagacaaa
     4081 cacctaaaca agcagaatca cgaaaagaat tgaaagaact attatctgta gaatcaggtg
     4141 gtattgtatt tacaactatg cagaaattcg aacctgaaga aggtcaagtg acaatggatg
     4201 ctttaacaga acgtaaaaat gtagtagtta tggcagacga agcacaccgc acacaatatg
     4261 gttttaaagc aacttacaat gaaaaaggtg aaggtataaa atatggttat gcaaaatatt
     4321 taagagacgc tttacctaac gcttcgttcg ttggttttac tggaacacct gtatcttcga
     4381 cagataagaa tacgcaaatg gtatttggta attatattga tgtatatgat atgacacagt
     4441 ctgtagaaga cggtagtacg gttaaaatat actatgaaag tcgtattatt ccattaaatt
     4501 taccaactga tttagatatt gatgatgcat atgatgtcat tacttttggc caagaagaag
     4561 atactaaatc tcgattgaaa tctaaatggt cacgtataga agctctatct ggtgcagaaa
     4621 aacgagtaca tgctttagcg actgaaatta ttaatcactt tgaaacaaga cagaaggcaa
     4681 tgaacggtaa aggtatgatt gtcacaatga gtcgtcgtat tgcagttgat ttatatgatg
     4741 aaattataag acttaaacct gaatggcatt ctgatgatga cgacaaaggt gtaattaaag
     4801 tcgttatgac aggttcatca agtgatccgc aaaacttcca aaaacatata ggtccgaaaa
     4861 agagaagaaa ccttttagag aatcgtatga aagatattaa tgatgaactg caactcgtaa
     4921 ttgtgcgaga catgtggtta acaggatttg atgtaccttc aatgcataca atgtacatag
     4981 ataaaccgat gaaaggtcat aatttaatgc aagctattgc acgtgttaat agagtattta
     5041 aagataaacc aggtggctta attgttgact atgtaggtat tgctgaaagc ctgaaggaag
     5101 cactaaaaga gtatacggac tctgatagag aacaaacagg tatagataca gataaagcgc
     5161 tagaactaat gttagtgaaa tacgatatca ttcaagatat gctatataac catgactatt
     5221 ctgactttga gtcagaagat caattaaatc gctataatgc tatctcaaat acgatggatt
     5281 atatcattgg attaggtgag aaagaaagag agcgatttgt gacaacagtt acagaacttt
     5341 ctaaggcttt tgcattatgt gcaacagagg aagctgctca agaactaaat agtgaaattg
     5401 cgtttttaaa agcagtaaaa tcaggacttg ttaaattatt agctccacct aatgaaggaa
     5461 gcaagcttaa aaagacacct gctgaaatag aagcagaaat aaatcaattg atttcaaagt
     5521 cagttgtaac tgaagaagtt gtagatattt atcaaacact cggaattgaa aatccagata
     5581 tctcaatatt gtcggatgat ttcttaaaag atgtagaagg actacagcaa aaaaatgttg
     5641 cagttgaatt gttgaacaaa ttactcaaag gacaagttaa gtcattaatg aaaactaata
     5701 ctactgtatc taaaaggttt tctgagatgc taagtaaatc aatacaaaaa tataataacc
     5761 gttctatcga agcatcaaaa gtcatagaag aattaattca aatggcgaaa gaaataaatc
     5821 aagaaaaaga aagaggaaaa gaattaggtt taagtactga agaaattgca ttttatgacg
     5881 cattagcttc acatgaaaca gcaaaagaag cgatggatga taaagaatta agggctattg
     5941 cacatgaatt aacaaaaacg gttaagaata atatgagcgt agactggtca aaacgtgaga
     6001 gcgcaaaggc taaaatgaga gtccaagtaa gacgactatt aaagaaatat ggttatccac
     6061 cagacataca aaaaatggca gtagaacaag tagtggaaca agcagaatta atggcaagtc
     6121 aacaatataa ataaatactg tttatattgt tgacctgtta gatacttttt taaaattaaa
     6181 catttaagac agagtatata aaaaagtgtc aatataccgg tagactatag agaaaaggag
     6241 attgatatga aattcgactt aattataagt aatattatga tagggatatt agtgatttgt
     6301 tctgcatttg ccttaatgtt tgtcttttat attcaaagaa agttaacgcc ggaacaatac
     6361 ttttcttttt cagaattctt tttaatagga agaggtttaa ctatcaagaa aattttgaat
     6421 agaatgatat tgattgctag ttttaactgt attttgtttt taatacttaa gaattttttt
     6481 gaaattgaat tagtatgtag tgtgtgtata ctaagtacat tgttgggttc gattttaatt
     6541 atttatccgg cgtttaaaat taggcatgat ttacctaaca atgagatgaa aagtttgttg
     6601 aactatatgt atgtatcttt tgttttttta gcgcttatta tttctactct tactgtattt
     6661 actttagtag tattatttga tgatattagt atagtaacac tttggcaaga gcataaaagt
     6721 ggaataattt tatatcttct attggtgata cctagtctat tttttaatcc tacaaattat
     6781 gaaaagaaaa tggaatatgc cattgaaaaa catcgtgaga gtaatagaga gataaatgag
     6841 acgataataa aaaataataa tgaaacaatt ataccagacg agtcgaaaag ttcttcacca
     6901 ttcaaaatta aaaaagtttt tagattgttg aataggatta tgaaagatga ttgaatatta
     6961 tttgaagaaa attatacatt tatttgaaaa taataaatgc gaaattttac atttaaaaat
     7021 gaattttaat gataactttg atatgttaag ttatatttat tgtattgaga acatgcatag
     7081 aggttcaaat attataaaga tagcggagta tatattagta aagtattttc aaaaatattg
     7141 tataaaaaaa gacttttcta taggtccatt tcaagttaaa aaaagttttt gtgtgtctaa
     7201 taatttatat ttagagtcac tagataaatt attggagttg cacagtagtg ctcatgtaat
     7261 taatgaattt attgaaaata aaaaatatta tttgaataat aatgagattt tatccttata
     7321 tcattcaggg aaggttatgg atactagctt ttcaacttta atgtatatag gattatttaa
     7381 acatttttct agttatttaa gaaaacacga ataaaaaaca actgatgata acaagttaac
     7441 aaattattaa atttaaatca ctctagttca taccaaaaag tctttaacac aaacaaaaaa
     7501 ggaggaaact taaattcctc ctcaaccttt attacaccta taattctatt ttaacgtctt
     7561 cgtccatttg ggcttcaaat tcatctagta gtgctcgtgc ttctgcttaa tttgaatcat
     7621 acaaggtgtt ttttgttatt cctaaaattt ggcatagcta aataaatctg tattttctat
     7681 ttgtcttttt tggcatttat gataacccaa gtatcttttg gaacggtaac tgtagttgtt
     7741 gattgaatta attcgttttc actttcatcg aagcttagta atgatttata taaatctgat
     7801 ttccaaaccc aaacttcttt ttgggtttgc tgtgttgcct tatcagtatt ctttacttca
     7861 tatttagctt gatgcttaac ggactcagat atattatttt tatccatttt aggcttgaaa
     7921 tgagttgtag gttttttatc cttaggatga tctctataga ccatgacata gttatttgta
     7981 ttttttccta tttcattgat tattaatata ttagctggat tatttttagg accaccagta
     8041 aaaatttctt ttttatttga tgtgattact ttcttttcca taccccaatg gttagtcata
     8101 ttagctgtaa taccaatgat tgttagtgtc aacgcaagag taaataatgt tcctaatata
     8161 tagcgtgtga ttttatgagg aattaataac caactaacaa aagtacataa agttaaaaca
     8221 atcgttgtta tcatattatt tatcctcact ttcaataata ttcattttta aaaatggaac
     8281 taaaatgata cctataattg caaagaaaat gccaattata aatgcagtat taaagccatc
     8341 gattgatgct tgttgagcaa ggtgtgcata tttgagtgga ttgctttctt ttaaactatc
     8401 tgcaggcata tggttgttaa taatattttg agtaacagat gtcagtaatg ctactgctat
     8461 agatgatgct acttgtctag cagtattatt tactgctgta gcatgtgtgc ctttttcaaa
     8521 tggtaaagca tccatcgcat ttgttgtgag tggcatcatt aaaattgcca caccaaacat
     8581 tcttactgca tatagaacaa gaataagtgt tggtgatgtg ttaactgtta aaaatccaaa
     8641 tggaactgaa gctaaagtta aaatagtgaa accaacgaac gctaatcttt taatgccaat
     8701 tttattgtac agtattcctg aaattggaga gataaatccc aacatcagtg ctccagctaa
     8761 aagtgttaaa ccagattcaa atggtgagaa accgtgtata ttctgtaagt aagtgggtaa
     8821 catcatttca acaccataca ttgccatagt tacaacgatt aaaccaattg tcgctatcat
     8881 gaaaccttta gatttaaaaa cgcgtaaatc caagaaagga tctttagatt ttaattgttt
     8941 gataacgaac aaggtaagaa caatgatact taaaaaaatt ggtaaaataa cgtaatttat
     9001 atttccccat ccttcgcttg caacgtttga aaatccccat aaaaataatc cgaaaccgat
     9061 acaagaaagt attagagaat agagatctaa tttaagttta cgattaggta taacatcttt
     9121 catgaagaag aagcttaata taaatgctat cgctataata atgattggaa gaacaaaaat
     9181 attacgccat gagtctgaaa ttgtaatacc tagtacctcg tggtttttgt ttaatatcca
     9241 accagcaaaa gttggaccca ttgcaggtgc gagacctact gctaaaccac tcagacccat
     9301 tgcagtacca cgttgtttta ttggaaacat ataaataatg atgatttgta acaatggcat
     9361 cattaaacca acagcaattg ctgtaacaat acgtccagct agaaatatta accagccatc
     9421 ttgatttgat ggtgcgattg cagtaagaat taatccgaat aatagggcgc cgtaagagta
     9481 tacatgtaac aatctagtag atatgcgcgt cgctaaaaat gccgaaagtg gtaccataat
     9541 accatttgcg agtaaaaacc aagttgttgc ttgttgagca gtactaaaat cgatatcaaa
     9601 atcgttcatc aaagtaggta gagcggtacc taatgaagtc tgcatcaatg caccagagaa
     9661 tgtagctaat aatataatgc tcattataat tttgggttta tattgattgc catgaatatc
     9721 taaattcatt gcattacttt tttgagtaga cataaagcaa gcctcctata ggtttttaaa
     9781 attaatactt tgaaaatata acacctactt tataaacaga acagaacaaa atcatatact
     9841 ttgtacaatt tgtgacactt tgttttattt tgtgttatat tcatttatag gagtgatcat
     9901 atggggtata aaaggaaaac ggtcttaact cagcgtaata taaaaaatgc tttagtgagt
     9961 ttattagaga acaataagtt tgatttcatt acaatcaatc aaatagtaga agaagcggaa
    10021 ataacaagaa gtacttttta caggtattat gatgataaat atgaattaat atcagaaata
    10081 gaagaagaaa ttttagaaca tattcataaa gaaaggcaaa agatagacga gaacgcttca
    10141 gagaagaatt tattagatat tgagatgttt aaatatctgt ttgaaacatt agagccatat
    10201 tcgaacacga tatatcgatt gttaggatat aatggtgatt ccagttttga gatgaaactc
    10261 aagaatgaaa tatcaagaag atttatagat atagaacaac gtaatcatat ttctcaagta
    10321 cgagcagact tagtaaagga atatgtattt gttattatga taaaaacatt acaatattgg
    10381 tcagctcata aagacgaagt agatattgat gaaatagctt taacaattag ggatatccag
    10441 ttaaaaggat taagaaaagc aatagggtta taattttaat gaataacaaa aaaggaggaa
    10501 cattatattc ctccttgacc ttcattacat ctataattca attttaacgt cttcgtccat
    10561 ttgggcttca aattcatcta gaagtgctcg tgcttctgca attgattgtg tgttcatcaa
    10621 ttgatggcga agttcgctag cgcctcttat gccacgcaca tagattttaa agaatctacg
    10681 caagctcttg aattgtcgta tttcatcttt ctcatatttg ttaaacaatg ataaatgtaa
    10741 tctcaacaga tctaatagtt ctttgcttgt gtgttcgcgt ggttcttttt caaaagcgaa
    10801 tggattatgg aaaatgcctc taccaatcat gacgccatca atgccatatt tttctgcaag
    10861 ttcaagtcct gtttttctat cgggaatatc accgttaatt gttaacaatg tatttggtgc
    10921 aatttcgtca cgtaaatttc taatagcttc gattaattcc caatgtgcat ctactttact
    10981 catttcttta cgtgtacgaa gatgaataga taaattggca atatcttgtt cgaagacgtg
    11041 cttcaaccaa tctttccatt catcgatttc atagtagcca aggcgtgttt taacacttac
    11101 cggaagtcca cctgctttag ttgcttgaat aatttcggca gcgacgtcag gtcttaagat
    11161 taagccggaa cccttaccct ttttagcaac atttgctaca ggacatccca tatttaagtc
    11221 tattccttta aagcccattt tagctaattg aatactcgtt tcacggaact gttctggctt
    11281 atctccccat atatgagcga ccatcggctg ttcatcttcg ctaaaagtta agcgtccacg
    11341 cacactatgt atgccttcag ggtggcaaaa gctctcggta tttgtaaatt cagtgaaaaa
    11401 cacatccggt ctagctgctt cacttacaac gtgtcgaaag acgatatctg taacgtcttc
    11461 cattggcgcc aaaataaaaa atggacgtgg taattcactc caaaaatttt ctttcataat
    11521 atatttatac cctctttata attagtatct cgatttttta tgcatgatga tattaccaca
    11581 aaagacgaac ttatacaaaa ggaattttag ttgatacaac catttgaaag ggaagtctaa
    11641 gagtagtcta aaatgaatgt tgtggtaagt tgatcagtat acagatcaag gattatcgta
    11701 ttagattgtt cattattaat gatacactac ttatgaaaat gattcagaat tttctttggc
    11761 tacttttaca gtaaagcgat tttttagtta tcttataaca aagacaaatt tataaaggtg
    11821 atattatgga agatttaaag cattctttaa aaagtttagg ttggtgggat ttattttttg
    11881 cgatacctat gtttctgcta ttcgcatacc ttccaaacta taattttata acgatatttc
    11941 ttaacattgt tatcattatt ttcttttcca taggtttgat tttaactacg catataatta
    12001 tagataaaat taagagcagc acgaaatgat tcattaatac gaatgtgatt aaacataaaa
    12061 ctgaaggagc gattacaatg gcgactaaga aagatgtaca tgatttattt ttaaatcatg
    12121 tgaattcaaa cgcggttaag acaagaaaga tgatgggaga atatattatt tattatgatg
    12181 gcgtggttat aggtggtttg tatgataata gattattggt caaggcgact aaaagtgctc
    12241 agcagaaatt gcaagataat acattagttt ccccgtaccc aggtgctaaa gaaatgatat
    12301 taattccaga ctttgacgaa gcaacaaatc tcactgattt atttaagacc ataaaaaatg
    12361 atttgaaaaa gtgaagtgtg ggtgcagaga gaactaagcc catcgataaa tggtcgcttg
    12421 ttaaagaaga gtgaccgtca ctcttcttta tgtgcatatt ttattttgtc tgttttgtta
    12481 acgatcagca gtgtaacaaa tatgagtaag gataaaatga gtataatata gaaaccgaat
    12541 ttatcattaa tttcattaat ccatcttcct aaaaatggag caatgaaact ctgcagtaac
    12601 aatgaaattg acgtccatat cgtaaatgag cgaccgacat atttatctga aacagtgttc
    12661 attatagctg tattcatata aattctgatt gatgaaattg agtagcctag tataaatgat
    12721 cctatgaata agtaaaatgc tgagtttatc caaataaata gtgctgaatt tatgactaat
    12781 atgaaatata acaaaaatat caatacttta gttgagattt tcttcgaaag aatagctgaa
    12841 attaaacctg cacataatcc tccaatgcca tataacatat ctgaaaaacc aaattgtaca
    12901 gacgaaattt ttaaaacatt atatacatat cctggtaatg atatgttaaa gatcattgta
    12961 aacaccattg gtatgattga aataactcca aaaataaata tcatcatgtt gtcttttaaa
    13021 aatttccatc ctaataaata ttcttgcaat aagctatttg ttgattcttc ctctgaatga
    13081 gttggtttat ctacatgcaa tctaaataac ataaaaatgc tgattagaaa catcattata
    13141 gtcatcgcta taattagagt gaatccattt atctcatata atattcctga taatccacct
    13201 gcaataaaca tacctgtttg caaactaatc tctaatagag aatttgcatc tgtatattga
    13261 tctggtttta aaatctgttt aactaaactt ctagatgttg ccatatacgt agtccaacct
    13321 atcccattaa caatcgcaaa tccaatcact aaataggtct caaatcctat cattacgagt
    13381 gctatgacaa tgagtaaata taatattacc tgaagaagat aggtgattaa aataatattt
    13441 cgtctattat atttatcggc tagtccacct attataggag aagctaagaa accggataat
    13501 acatttaaag ctaacataat acctaatagt tgggagtcgt tagttttgtc gattaaatac
    13561 caattagccc caactgtact aattccaact ccgaatgctg aaattatttc tgctaaaaag
    13621 aacaatctga agtttttaat tttcaacaaa tcagtcataa atatcacctt ttttcaatgc
    13681 aagatttata tttgcgagct cttctataaa ttgagagtcg tttaaaatat cgaatggttt
    13741 attgccttcg ccgatcaaaa atctatagtt agtaatattc ataaactcaa atattaattt
    13801 gaattggttg actaaaggtt gtgctttggt atgtggattg tcgccaccta tgattaaaat
    13861 caaatacttt ttttgtgaca tgatttcttt gaagttgtct atttgcgtat ctcgcaatga
    13921 ctcggtccat ctatcaatga agagttttaa agacgcactc atggagtacc aatagagtgg
    13981 tgttgaaaaa ataataatat ctgattctaa aactttgatt aaaatttgtt cgtaatcatc
    14041 attatgaaag ttggcacctt tgctatgacg attatctgta accttttcaa tgttgctttg
    14101 atataaattc acaaagttga catttaaatt cttcaataga ttctctactg cgatacctga
    14161 attgccatct tttctactac ttccaaataa acaagtaatc atagtcataa ctcctttcga
    14221 tttaccttta taataatatt taatatatta ttattaaatc agaattctta gaattcagga
    14281 ttcgataaaa gtgaatccta aaggaggtac tactttgaac ttaaacattt taaaatcatt
    14341 tttagtaact agtgaaacaa agaaccttac taaagcatca gagttactta actattcaca
    14401 gtcaactgta tctacacata ttgaaaaatt agaaaggcaa ttagatgtta aattatttta
    14461 tagaaaaaaa tatggtatgg aactaacgga agaaggctta gcatacgtta aatacgctaa
    14521 agtgatttta gatagtaata gcgaatacga gagagaaata aaaggacttt acaataagaa
    14581 ggtaaatata agtattaaca tgcaagaaag tcagtatttg tatcgctact ataataagat
    14641 tagtgaatgg ttagctgaac acccatatgt aaacttgaag tttaaatccg cacattctaa
    14701 tttctatatt aaagaagaaa ttgctaattt caaatcggat attagcctta tcacagacga
    14761 aaagattatt aatagtaact taactgctat tcctataact gaagaacgtt taatatttgt
    14821 tactaacaaa gagatgaaag atttcaaatt aaacgatatt caaaaccata cattacttgt
    14881 tactgaaaaa gggtgtagtt acagagaaca gttagaaaag attctctata aatatagctt
    14941 ttcaacaaaa caaatgattg aatttctagg aattgagtca ttgaaaaaac acttgaaaaa
    15001 ttcagatggg attgcgctat tgccggagtt tattgttgca gatgaattac aaaataaaag
    15061 tttgtttcaa atagatgtcg atgtcgatat tccgaattta gaaacaactt tgataattaa
    15121 tcctgaatcc agtaagcaag tactagaatc ttttgtaaaa gatgtctttt tataaatatt
    15181 ggtgaaaacg tgtagttatg gtgaaactca aagataataa tttaaatgag atgttaatga
    15241 aaaagtaatt caatataaaa acaggtgatt tatatcttta ataaggatta tttctagttg
    15301 aaatttcaat tgcgggcatt cattttcaaa atagtaaaga atttaataga tgaaaacctt
    15361 tgaatcatac tagttagtat ggattgatta atattttaac ctgctaaatg agtagcttat
    15421 gtattttaaa tagctgtcat ctagcaggtt ctttattatt aataagttca gataaattat
    15481 tttagtctgt tttctaatgt tgataataat aactttaaat ctgtactttc attgtgagat
    15541 atatagtaca tcataaattt ttatatttgg attgagactc tttggaagat tttcaataaa
    15601 tgaatatttc acaaacttcc acttatcagg attataaatt ataatttctg caactgcatt
    15661 atcgaagatt ctaaacaatt ttttgatttc tatttctttt agagataaag tagggaaaat
    15721 gtcgatatat tcttcaagcg cataaagact atgtttaaca gaatcggtta tgttcattga
    15781 atatatcaca ccaatattta tattttgcca tccaaaagaa gaaataacat tatcataaaa
    15841 tccattgaat ataaattcag tcatcccctc tgaacttctc cataaatata atggtgaata
    15901 agtatttgta atgcaattac tagttgtttg acttattaaa taagctttta taattaaatt
    15961 tttaaatcca tcagtcttat aaccatttaa tcgaactcta tctctaatta tttccatatt
    16021 gtaatcacta ggcaacttaa catgatattg cattgcatgc atttagcata ccccctttta
    16081 taaaaaggat agcaataata agtaaaatct catattatcc aattgtgata tagttatcat
    16141 aaaaagtgat aggtgattaa attgaacttt aatgatttgg aaatttttat aactgtatgt
    16201 gaagaagcat ctatcaataa agctgcaatt aaacttagat atgcacaatc taatatatct
    16261 caaagaatta gcaagcttga aaatgaatta ggtgtagttt tgctttttag aaatcaaaaa
    16321 ggtgctaagg caactaaagc aggcgaagaa tttttagcgt atagcaaaaa agtattaaga
    16381 gatacagaga ctataaaaaa taaaatgaaa tataacacta tgtctatttt atgctcagaa
    16441 ctgttattta attatttatc tgagagcgaa gaaattatga tgtcgaataa ctcaattaat
    16501 tttatttcta gtggaaatat tagaaaagct atagaaaaaa ataattatga taaggttatt
    16561 tcattcataa aaattaatga ctcaaattat agacttagta atgttgatac tatgaaagta
    16621 acgctttaca gtaatggaag taattatgat aaagagtctt tactaataaa taaagatgag
    16681 ttttgtcctt taaggaaaat aactttagat attaagcttg attcacaacg ggtaatggaa
    16741 tttgattcat tggcagcaat aataaactta gttgaacaag gaaaaggaaa ggctttatta
    16801 cctatgactt ttgagaataa aagagatata gtacaggaca tttctaagat atttgaagtt
    16861 agctactata cttataatca tattatgcat cattaattga aagttgattg agtttaaatt
    16921 acaagaacga tattaagatt ctagtagtta gaatgagcga tgtgatagaa aagaattttt
    16981 gctttttaat tggtaaattc gttattttaa agtagtggtc tttgtagata ggaaaaagcg
    17041 gattccctta tcagcctttt ccactcataa aatttattat tgtaactttt atgaggtgag
    17101 gagctaaata ttgttcgaac taaattttac ttagaccttt tctctttcaa ttctttttta
    17161 atttgatcag gagatttcct atcctttgat ggttttagta atttctgtac cgtttcgtct
    17221 ctaagcatat caccaccaaa ctgatgatta tatgcaggta ccatgtaagc aacaaaaccg
    17281 tcgtccttat tattattgat atagccttca atgattcttt catcaagagg acctttgtcc
    17341 aaacttgtaa aatgtaccga cttaatcgta ttaggctctt ttgtattatg tttaagatac
    17401 aatgtaatac gttcttgttg ctgcttgtag taaaattctt tttgtttcat aagctcgtta
    17461 tacttcatta taagaatgac gcctacaata atgaaggcta tagtgaatat agtaccgata
    17521 ataattaaaa tgtatttttt tgacatgata tcaactccga tattagtaag ggcataggag
    17581 caattgaaat ttccaaacaa ggtacacgag tgcttctgaa tttatcggca cgcttttaca
    17641 tagatcaaaa gaacgcgcac taaaataatc attttatcta tgtaacttac atctttgata
    17701 ctacagaagt tcgtgcattt gttcaatcgt ctcataacca ttaaatagcg ttaattatga
    17761 atgaagacat ctataacatt tatttatctt ataacatagt acaattacaa agcatcacaa
    17821 cggcgactgt actcacctta aatcataacg acaaccgcta aaaaatgatt tgaaaaacta
    17881 atcattaatt gccatactca actattttga aaagtatcaa tttcacatta tcaaattatt
    17941 gagtatctca atttattgtt atacacaaac agtatttttg ttatcataga gttaataaat
    18001 ataataaatt gaataagtaa cttcacaaaa attagaatga ttcaattcaa tcacaattat
    18061 ttgaaaatag aggtgagcag gtgaacgata tgttaattag tcttgtaatc ccagtttttg
    18121 ctttgttagt tattggtggt attatttgga tgattataga aggtatagta catatttcaa
    18181 aaaagaataa agcaattgat aactttttta accaagttaa taaagtaagt gagacatata
    18241 aattcgctac tactttttta tttctaatct tggctacggc tggtatttct caattttatc
    18301 tatattatat agtatcagcg tttctttttt ggcttgtcat acttaccttt ggtattgcag
    18361 gtatcatttt tttaatgcca tatggattat gttttctacc gttttataag caaaaaaaga
    18421 aaaaacagac atttaaaaaa tacatggttt acactacgat tggtttgtca atttgtctag
    18481 gcttatctct agttttggtt cacactacga aaatttatat ggacgaaggt ggcgtaagat
    18541 actattacgg tagttttgta atgaaacaag cgggcggtta tgcttattta gctttagcag
    18601 tactttcaac gttgttaatt gttgcgaaaa aagctacaaa taaaaataaa gaaatcgaaa
    18661 ccgtcgacaa tacaaatata acggaaagat aattaaggga gtgctcattc aggagtgctc
    18721 ttttttgatg tccaaattta gttgcaaatg aaggcataga agaaattttt atagtcattt
    18781 attggataat gaattatggt catatcgatt aattttatta gtgaggattt tacaaacatt
    18841 tgttgaataa atatggtaat gataatatat gaatattttt gaaaaaacac taatatgatt
    18901 aaattatttg ttaaaatggc attaagtaaa aaacaaacag ggaacaaggt gggatttcat
    18961 gagtcaattg ctaaatgata cgttatcggc ttggttgtta attgaatctt taagtccagg
    19021 agaagtaaat tttacagcgg aagatatact ctcagctgaa cattttaaaa atggtgcaaa
    19081 gcaagcacaa cttcaaagtt ttgatgaata ttttgaaata tggaatgctg aacgctttat
    19141 tatatcagaa gaaaaatcag agactgggga acttatattt aaattttata gacattgctt
    19201 ccgctataat gaaattaatt tgaaaattca ggatattttt gatgattatt ctgagattca
    19261 taatccaaat gggacacact gttatggtta cacatttaac acagataaac acggcaaagt
    19321 gatagttgat tctatacata ttccgatgat tatgagtgca ttaaaagaaa ttgaaaagaa
    19381 caaaaatgcc aatatagaag aaaaatttaa tgattctgtt gaaaaatttg ttcaaaaagt
    19441 aaaagaaatt ttagcagatg aaccaattaa tgaatttaaa ttgaagaaga tggacaaagc
    19501 ttatgatgag tacttttctg tattaaattc aaagaaagat ggattatttg gacattatgt
    19561 agcaatagaa tatgtgaaag atagtgattt accacagccg gaatttaaca gcttcttcat
    19621 aagtgatatt gagaaagcaa gaaaatctcc caaccaaact ttaattgatt acattgaagg
    19681 tgtagaagaa agtcagcgca tagaagtaga tgaaaataaa gaaatgtttg acaaattttt
    19741 acatccttca cgtttgcctg atggacgatg gccatcacag actgagttta gattgtcttt
    19801 aatgcaacaa cttgctgtaa accaaattac gagtggtaat gaaagaataa gttcagttaa
    19861 tgggccacca ggtacaggta agactacttt attaaaagat atatttgctc atctagtagt
    19921 tgaaagaggt aaagagttag ctaaactaaa taatcctaaa gatgcatttg tcaaaacaaa
    19981 aattcatgaa acggatgata aatacgtata cttactaaag gaatctattg ccaaatataa
    20041 gatggtagtc gcatctagta ataatggagc tgttgaaaat atatctaaag atttaccgaa
    20101 aattgaagaa attataagaa atcccgaaaa atgtaaattc cctaaatatg aacagaatta
    20161 tgcaaattta gcacatgaat taaaagattt tgctgaaata gctgaagatt tgattggtga
    20221 aagtgcctgg ggcttatttt ctggagtttt tggtaaaagt actaatatta accaagtatt
    20281 gagtcatatg ttaaaacaag atgcgaatga tattggcttt gctaaattac tacaaaatga
    20341 gaataatcgt atgagttata acgagttaat gagtgaatgg caatcacatc aatgtgcatt
    20401 tttagaagag ttgaggcatg ttgaaatgtt aaaagaagaa tctattagag catatgatgt
    20461 ttataaaaat tgtgagtctt tctctaagat tgaacaggtt attaatagtg aaaaaacaag
    20521 tattgaagaa cagatatatc atttagataa tgaaacgtta cgagacaata aagaaattga
    20581 agatttgggt gatcgaatta attataatac aaagcaactc gaaactttaa atgagttaat
    20641 taaatccatc aaagaaagca acaaaggttt tattaacaaa ctgaaagcga tgtttaattc
    20701 agaagaagat gaaagctata aagatcataa taaagagaag caacaattat taacacaaca
    20761 gttagagtta gagaaatgta aaaaaaacaa acatgaagac cttgttagca aactaaaaga
    20821 aaaagagaaa ttaattaaac aattaactaa agtacagttg caattagacg agttaaattc
    20881 acaattacaa gagttagaag catatcgtat tgagtcaaaa attacaattc cagaaaaaga
    20941 tttttggagt gacaacaatt atgatgagcg ccaagttact aatctgtgga cgagtgacga
    21001 acttcaatac agacgtgcca tgcttttttt aagagcaatg atattgcata aattattatt
    21061 gattgctaat aatacaacta tttattatgc gattaatgat tttaaagata gaaggaaatt
    21121 aattgatgca aatccagata aagtacacaa cgcatggaat gtgatgcatt taatatttcc
    21181 agtagttagt acgacgtttg caagctttaa atctatgtat gggggcatac caaaagattt
    21241 catagactac ttatttattg atgaagcagg acaagcaata cctcaagcag ctgtgggagc
    21301 attatatcgt tcaaaaaaag ttgtagctgt aggtgatccg attcaaatag aaccggttgt
    21361 gactttagaa agtcatttaa ttgataacat tcgtaaaaat tatcatgttc cggaatatct
    21421 agtttctaaa gaagcttctg tgcagtctgt tgcagacaac gccaatcaat atggcttttg
    21481 gaaatctgat gctactgata gtaatcaaaa aacatggata ggcatacctt tatgggtgca
    21541 cagacgatgt ttaaaaccta tgttcacgat agctaaccaa atcgcttata ataataaaat
    21601 ggtgttgcca agtaatatta caaaagtagg taaaacaggt tggtatgacg ttaaaggaaa
    21661 cgcagttcaa aaacaatttg tgaaagagca tggtgaaaaa gtagtgggat tattagctga
    21721 tgattggatt gaagcaatta aggaaggtaa aaatgaaccg agctcatttg taatatcgcc
    21781 tttttcagca gtacagcaac agattaaacg tatgttaaag caacaactac cgactagaat
    21841 tgatattgaa cgtacaaaaa ttaatcaatg ggtcgataaa tccattggta ctgttcatac
    21901 ttttcaaggt aaagaggctc agaaggtgta ttttgtaata ggtactgata atacccaaga
    21961 tggtgctgtg aactggtcat gcgaaaaacc aaacttgtta aacgttgcag tgacaagagc
    22021 taagaaagag ttttatgtaa ttggcgacat gcaaagaata cagatgaaac cattttatga
    22081 gacgattttt aaagaaagaa atgtaaaatg aaattgaaat aacagtatta cttgatactt
    22141 aattatcgag caatttatac attttaaaag gagcaaaatt gaataatgaa gaaatttaac
    22201 aactggatat taaatgcaat aagtggatct caaacagaca agaatgaaac aactgaagaa
    22261 ttaaaagggg caaaatttat cattttatat gcatattcaa tgctcgtttt gcttgcgtta
    22321 gtaatttcta acatattcat tcacattttg gagcctaaac tatcaattac cactcaaatc
    22381 atcatcgttt tgattttaat tgaaacacta attggactgc gtttcttgaa agcgtacgat
    22441 gttaagcgtg gcaaagataa agaaaataag aaaaatagta aggatttcgt taaactaaaa
    22501 tcaattttag tagcaatttt atttacatca ttggcgctga cagcaggcac tgtagctgat
    22561 atatacggtt tcactgactt aggaaatact agaagtgatt taatcgtttg gagcataggt
    22621 ggtattatat ttggcctcgt atgttacaca atggaagata aaaaataacg ataaggagct
    22681 ggcgattata aagctagctc cttttttaac t
//
LOCUS       DAPSKH010000045        22428 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPSKH010000045 DAPSKH010000000
VERSION     DAPSKH010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22428)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22428)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22428
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.045"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..209)
                     /locus_tag="RPH49_001849"
     CDS             complement(<1..209)
                     /locus_tag="RPH49_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDY5124990.1"
                     /translation="MSDVSLKLSAKDIYEKDFEKTMARGYRREEVDAFLDDIIADYQK
                     MADMNNEVVKLSEENHKLKKELEEL"
     gene            complement(223..786)
                     /locus_tag="RPH49_001850"
     CDS             complement(223..786)
                     /locus_tag="RPH49_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDY5124991.1"
                     /translation="MVKTVYVTGYKSFELNIFKDDAPEVHYLKQFIKHKIEQLLDEGL
                     EWVLIQGQMGIELWTAEVVIELQRTYDSLKFAVITPFQGHTEKWNEHNQSKYANIIKH
                     ADYVDSIFHTPYQGPFQFKQADQFMLEHSDQTLLIYDEEQEASPKFFKQMLVDFMDKT
                     NYTCDIVTFDELTAFINDLQWSEDQSF"
     gene            complement(779..1129)
                     /locus_tag="RPH49_001851"
     CDS             complement(779..1129)
                     /locus_tag="RPH49_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YppE family protein"
                     /protein_id="HDY5124992.1"
                     /translation="MNDVVESLIYEVNNMQQNFENVKSQQQDHDFYQTVKPYTEHIDS
                     MLNEIKLHREFIIEVPYMNSRKFELLIANIEQLSVECHFKRTSRKLFIEKLKSVQYDL
                     QNILDGVTKEGTHG"
     gene            1617..2294
                     /gene="recU"
                     /locus_tag="RPH49_001852"
     CDS             1617..2294
                     /gene="recU"
                     /locus_tag="RPH49_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDY5124993.1"
                     /translation="MLCIINNVYYQTCVVKFMNYPNGKPYRKNSAIDGGKKTAAFSNI
                     EYGGRGMSLEKDIEHSNAFYLKSDIAVIHKKPTPVQIVNVNYPKRSKAVINEAYFRTP
                     STTDYNGVYQGYYIDFEAKETKNKTSFPLNNIHDHQVEHMKNAYQQKGIVFLMIRFKT
                     LDEVYLLPYSKFEIFWKRYKDNIKKSITVDEIRKNGYHIPYQYQPRLDYLKAVDKLIL
                     DESEDRV"
     gene            2291..4474
                     /locus_tag="RPH49_001853"
     CDS             2291..4474
                     /locus_tag="RPH49_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDY5124994.1"
                     /translation="MTENKGSSQPKKNGNNGGKSNSKKNRNVKRTIIKIIGFMIIAFF
                     VVLLLGILLFAYYAWKAPAFTEAKLQDPIPAKIYDKNGELVKTLDNGQRHEHVNLKDV
                     PKSMKDAVLATEDNRFYEHGALDYKRLFGAIGKNLTGGFGSEGASTLTQQVVKDAFLS
                     QHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKD
                     LNLAEEAYLAGLPQVPNNYNIYDHPKAAEDRKNTVLYLMHYHKRITDKQWEDAKKIDL
                     KANLVNRTAEERQNIDTNQDSEYNSYVNFVKSELMNNKAFKDENLGNVLQSGIKIYTN
                     MDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDVVNRNQATD
                     PHPTGSSLKPFLAYGPAIENMKWATNHAIQDESSYQVDGSTFRNYDVKSHGTVSIYDA
                     LRQSFNIPALKAWQSVKQNAGNDAPKKFAAKLGLNYEGDIGPSEVLGGSASEFSPTQL
                     ASAFAAIANGGTYNNAHSIQKVVTRDGETIEYDHTSHKAMSDYTAYMLAEMLKGTFKP
                     YGSAYGHGVSGVNMGAKTGTGTYGAETYSQYNLPDNAAKDVWINGFTPQYTMSVWMGF
                     SKVKQYGENSFVGHSQQEYPQFLYENVMSKISSRDGEDFKRPSSVSGSIPSINVSGSQ
                     DNNTTNRSAHGGSDTSANSSGTAQSNNNTRSQQSRNSGGLTGIFN"
     gene            complement(4992..5333)
                     /locus_tag="RPH49_001854"
     CDS             complement(4992..5333)
                     /locus_tag="RPH49_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5124995.1"
                     /translation="MTNITKEVFDNLEQEIDVFAKNKTLGSSEAKPYLDEYHSKIIDY
                     FKQVNDITGNIDFDNLNQYPVVPMNFKERYDYMIERKYHFMGYRQMKTFKTELIKMNA
                     SYQTRLKNKQV"
     gene            complement(5338..5997)
                     /gene="nth"
                     /locus_tag="RPH49_001855"
     CDS             complement(5338..5997)
                     /gene="nth"
                     /locus_tag="RPH49_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDY5124996.1"
                     /translation="MVSKKKALEMIDVIANMFPDAECELKHDNPFELTIAVLLSAQCT
                     DVLVNRVTTELFKKYKTPEDYLAVSDEELMNDIRSIGLYRNKAKNIKKLCQSLIDQFN
                     GEIPQTHKELESLAGVGRKTANVVMSVAFDEPSLAVDTHVERVSKRLGINRWKDNVRQ
                     VEDRLCSVIPRDRWNRSHHQLIFFGRYHCLARKPKCDICPLLEDCREGQKRYKASLKE
                     A"
     gene            complement(5987..6673)
                     /locus_tag="RPH49_001856"
     CDS             complement(5987..6673)
                     /locus_tag="RPH49_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HDY5124997.1"
                     /translation="MDKYQLKARPVVIRRELLDHYSDLGLDEQDLVILLKLIYASETS
                     NKQPSIELLQKGSTMQPRDITMVIQNLIQRELLELQVQKDEEGRFTEYMNLDPFFEKL
                     SHILKQQSMETKEQNSKEKFKQLFRVLEDTFARPLSPYEIETLNQWIDVDKHDTAIIQ
                     AALDEANSLNKLSFKYMDRILLNWKKNNVKTIDDSRKIREKFNKPKMTHTVKTVPKFD
                     WLNGENLDGK"
     gene            complement(7001..8293)
                     /gene="asnS"
                     /locus_tag="RPH49_001857"
     CDS             complement(7001..8293)
                     /gene="asnS"
                     /locus_tag="RPH49_001857"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDY5124998.1"
                     /translation="MKTTIKQAKDHLNQDVTIGAWLTNKRSSGKIAFLQLRDGTGFMQ
                     GVVVKSEVDEEVFKLAKEITQESSLYVTGTITEDNRSDLGYEMQVKSIEVISEAHDYP
                     ITPKNHGTEFLMDHRHLWLRSKKQHAVMKIRNEVIRATYEFFNKDGFTKVDPPILTAS
                     SPEGTSELFHTKYFDQDAFLSQSGQLYLEAAAMAHGKVFSFGPTFRAEKSKTRRHLIE
                     FWMIEGEMAFTNHAESLEIQEQYVTHVVKSVLENCKLELKMLERDTSKLEKVATPFPR
                     ISYDDAIEFLKAEGFDDIEWGEDFGAPHETAIANHYDLPVFITNYPTKIKPFYMQPNP
                     ENEETVLCADLIAPEGYGEIIGGSERVDDLELLEQRVKEHGLDEEAYSYYLDLRRYGS
                     VPHCGFGLGLERTVAWISGVEHVRETAPFPRLLNRLYP"
     gene            complement(8615..11308)
                     /locus_tag="RPH49_001858"
     CDS             complement(8615..11308)
                     /locus_tag="RPH49_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HDY5124999.1"
                     /translation="MGMATYAVVDLETTGNQLDFDDIIQIGITFVRNNQIIDTYHSMI
                     RTNLEIPPFIQALTSIEENMLQQAPYFNQVAQEIYDKIKDCIFVAHNVDFDLNFIKKA
                     FKDCNIQYRPKKVIDTLEIFKIAFPTDKSYQLSELAEAHGINLANAHRADEDAATTAK
                     LMILAFEKFEKLPLDTLKQLYYLSKQLKYDLYDIFFEMVRQYDAKPLDKSYEKFEQII
                     YRKQVDFKKPTTNYNGSLKSLYSKAVDQLGLTYRPQQLYLAETILDQLMHSEKAMIEA
                     SLGSGKSLAYLLAALMYNIETGKHVMISTNTKLLQSQLLEKDIPAMNEALNFKINALL
                     IKSKSDYISLGLISQILKDDTSNYEVNILKMQLLIWITETPSGDIQELNLKGGQKMYF
                     DQKIETYVPARHDVHYYNFIKRNAQNIQIGITNHAHLIHSDVENSIYQLFDDCIVDEA
                     HRLPDYALNQVTNELSYADIKYQLGLIGKNENEKLLKAIDQLEKQRILEKLDIAPIDI
                     FGLKASMNEIHELNEQLFSTIFTIINDSDVYDDDIHRFHNVFTFETKDILKDLHAIID
                     KLNKTLEIFNGISHKTVKSLRKQLLYLKDKFKNIEQSLKAGHTSFISIKNLSQKSTIR
                     LYVKDYAVKDVLTKQVLEKFKSLIFISGTLKFNHSFEAFKQLFNKDVHFNTFEVNTSL
                     QSAKNTSVFIPSDVASYQYKNIDEYVASIVSYIIEYTTITSSKCLVLFTSYKMMHMVQ
                     DMLNELPEFEDYVVLTQQQNQNYKIVQQFNNFDKAILLGTSTFFEGFDFQANGIKCVM
                     IAKLPFMNKHNAKYWLMDSEFTSTFKEYVLPDAVTRFRQGLGRLIRNENDRGIIVSFD
                     DRLINSNYKNFFEQTLENYRQKKGDIQQFGKLLRQIQKKKK"
     gene            complement(11332..12303)
                     /locus_tag="RPH49_001859"
     CDS             complement(11332..12303)
                     /locus_tag="RPH49_001859"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDY5125000.1"
                     /translation="MSKYSQDVLQLLYKNKPNYISGQSIAESLNISRTAVKKVIDQLK
                     LEGCKIDSVNHKGHLLQQLPDIWYQGIIDQYTKSSALFDFSEVYDSIDSTQLAAKKSL
                     VGNQSSFFILSDEQTKGRGRFNRHWSSSKGQGLWMSVVLRPNVAFSMISKFNLFIALG
                     IRDAIQHFSQDEVKVKWPNDIYIDNGKVCGFLTEMVANNDGIEAIICGIGINLTQQLD
                     DFDESIRHRATSIQLNDKNKLDRYQFLERLLQEIEKRYNQFLTLPFSEIREEYIAASN
                     IWNRTLLFTENDKQFKGQAIDLDYDGYLIVRDEAGESHRLISADIDF"
     gene            complement(12290..13492)
                     /locus_tag="RPH49_001860"
     CDS             complement(12290..13492)
                     /locus_tag="RPH49_001860"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499992.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDY5125001.1"
                     /translation="MDKSLFEQARPILEQIQDNGFEAYYVGGSVRDYVMGRNIHDIDI
                     TTSATPDEIESIFSHTIPVGKEHGTINVVFNDENYEVTTFRAEEDYVDHRRPSGVTFV
                     RDLYEDLQRRDFTMNAIAMDTAYKLYDYFDGQQDINNRIIRTVGIAEERFQEDALRMI
                     RCLRFQSQLSFDIATETFEAMRTQMADIKFLSIERIVIELTKLMRGINVEESFNHLKS
                     LKAFNYMPYFEHLDMNQINVTEAIDLELLIAIASVKFDINYSLKPLKLSNRQVKDINQ
                     YIQIMNALPSIITKEQLKMFVYDYDTNLIKNVMVAADVLKANDIQGHEPLIVNLQTID
                     ETLHRLPMHNRKDMMVNGGVLMAHLNAKSGPWLKDVLRQIEIAIVTGKVSNEETEILK
                     WVDNHVKI"
     gene            complement(13497..14639)
                     /gene="bshA"
                     /locus_tag="RPH49_001861"
     CDS             complement(13497..14639)
                     /gene="bshA"
                     /locus_tag="RPH49_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-alpha-D-glucosaminyl L-malate synthase
                     BshA"
                     /protein_id="HDY5125002.1"
                     /translation="MKIGITCYPSMGGSGIIATELGIKLAERGHEVHFITSNIPFRIR
                     KPLPNMIFHQVEVNQYAVFQYPPYDITLSTKIAEVIKEYDLDLLHMHYAVPHAICGIL
                     AREMSGKDIKIMTTLHGTDITVLGYDHSLQGAIKFGIEKSDIVTSVSKSLAQETHEII
                     ETNKEIIPIYNFVRENEFPTKHNTALKSQFGIAPDEKVLIHVSNFRQVKRIDTIIETF
                     AKVREKIPSKLILLGDGPELVPMRQLTKELNVEEDVLFLGKQDCVSEFYQLSDLVLLL
                     SEKESFGLTLLEAMKTGVVPIGSNAGGIKEVIKHGETGFVVDVGDCDSASDYAIRLLE
                     DKALYNKLQKNMLADIAERFGSELITDQYEYYYQKMLNEHNKSKGE"
     gene            complement(14877..15194)
                     /locus_tag="RPH49_001862"
     CDS             complement(14877..15194)
                     /locus_tag="RPH49_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDY5125003.1"
                     /translation="MKSMVEMQREVDEYIGQFKTGYFSPLANLARLTEEVGELAREIN
                     HTYGEKKKKDSEEANTIKAELGDNLFVLLCLANSMGIDMTESFNETMEKFNTRDKNRF
                     ERK"
     gene            complement(15531..16211)
                     /locus_tag="RPH49_001863"
     CDS             complement(15531..16211)
                     /locus_tag="RPH49_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002456509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDY5125004.1"
                     /translation="MIIYFVILMVLPLWAQHKVKSNYEKYSQVRSTSGKTGREVALEI
                     LHANGIYDVEVVKGEGFLTDHYDPKKKVVSLSPANYDRPSVAGTAIAAHEVGHAIQDH
                     QGYWFLRFRAALVPVANLGSSLSYMIIMLGIILTAIGSAFGSTALWIGAGLMSLAVLF
                     SIVTLPVEFDASSRAMKQITALNIVNEKEYKHARKVLSAAAMTYVAATAVAVAELVRI
                     ILIARSSD"
     gene            complement(16283..16870)
                     /locus_tag="RPH49_001864"
     CDS             complement(16283..16870)
                     /locus_tag="RPH49_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1405 domain-containing protein"
                     /protein_id="HDY5125005.1"
                     /translation="MTINTFWQYTLYQRSWLMMLLICNILGMIYGYIWYGEQLSHTPW
                     HFKIFVPDSPTAILYLVISISLILIQKQNSIIDALAFVTLFKYGIWAVIMNILFIIEQ
                     GDITVNGLVLMFSHSIMAVQAIYFYPRFKRSMIGISVAMIWVFLNDYIDYFHLQFPYY
                     DFITTHVWQIGVLSCCLSVFGLLLYIELNKLLKCK"
     gene            complement(16860..17435)
                     /locus_tag="RPH49_001865"
     CDS             complement(16860..17435)
                     /locus_tag="RPH49_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDY5125006.1"
                     /translation="MSETLNQIKESFIEYLLFQYRFKSRIAVWVLNYIKVNEAKLANI
                     HFVDTKINHHETLEIAEVGSHASAIQFTKRNIKLMNTNEIFDYIANHNCAFDIQIHFA
                     NVSKREQRLDDLIVAQLTESPSYQTYLHDLNSMAIDRHKHALLIDYLLHNIDLSLQMN
                     EKQRFYQLTQILNTLKLVNKHNQFEDLADDD"
     gene            complement(17449..18693)
                     /locus_tag="RPH49_001866"
     CDS             complement(17449..18693)
                     /locus_tag="RPH49_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125007.1"
                     /translation="MEDIYKLIDDINLQKLENLDSRVNEAITTDNDDALFILGETLYN
                     FGLMPQGLEVFRVLYHKYPDESELLIYFIEGLMSENQTDEALEYLSYVEPSPEKLMLE
                     ADLYQQINMMEVAIDKLQEALELEPNDPIIHFALAEMLYYDGQYLRATSEYETVLETG
                     EYQVNGVNLFSRMADCSLQSGNYSDAIRLYDEINEDEMTSEDYLKKAISYDKNDITQE
                     AIKIMTTLLSKDPDYIQGYLYLQSLYENEKNYPDAIETGKEGLRLSQFYKELMYTTGC
                     LEIEHGDANEGVLLLKQALEVDNAYQEPLLILSDLYRNEEDYEAIIELLTYVDEEDLD
                     PTFMWHLAFAYGQEERDKEAQHFFELAYPTMKTNIDFMSDYYFYLIEIGQKEQAITIL
                     NQLLELEPSNENWHDELSRLQS"
     gene            complement(18700..19998)
                     /gene="aroA"
                     /locus_tag="RPH49_001867"
     CDS             complement(18700..19998)
                     /gene="aroA"
                     /locus_tag="RPH49_001867"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDY5125008.1"
                     /translation="MVNEQIIDISGPLKGEIEVPGDKSMTHRAIMLASLAEGVSTIYK
                     PLLGEDCRRTMDIFRLLGVEIKEDDEKLVVTSPGYQSFNTPHQVLYTGNSGTTTRLLA
                     GLLSGLGIESVLSGDVSIGKRPMDRVLRPLKSMNANIEGIEDNYTPLIIKPSVIKGIN
                     YKMEVASAQVKSAILFASLFSKEPTIIKELDVSRNHTETMFRHFNIPIEAEGLSITTT
                     PEAIRYIKPADFHVPGDISSAAFFIVAALITPGSDVTIHNVGINPTRSGIIDIVEKMG
                     GNIQLFNQTTGAEPTASIRIQYTPMLQPITIEGELVPKAIDELPVIALLCTQAVGTST
                     IKDAEELKVKETNRIDTTADMLNLLGFELQPTNDGLIIHPSEFKTNATVDSLTDHRIG
                     MMLAVASLLSSEPVKIKQFDAVNVSFPGFLPKLKLLENEG"
     gene            complement(20008..21072)
                     /locus_tag="RPH49_001868"
     CDS             complement(20008..21072)
                     /locus_tag="RPH49_001868"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDY5125009.1"
                     /translation="MKLQTTYPSNNYPIFVEHGAIDHISTYIDQFDQSFILIDEHVNQ
                     YFADKFNDILSFGNVHKVIIPAGEKTKTFEQYQETLEYILSHHVTRNTAIIAVGGGAT
                     GDFAGFIAATLLRGVHFIQVPTTILAHDSSVGGKVGINSKQGKNLIGAFYRPDAVIYD
                     LDFLNTLPFDEILSGYAEVYKHALLNGKSATHDIEQHFKDRASLQSLNGIDKYITKGI
                     ETKLNIVVADEKEQGVRKYLNLGHTFGHAVEYNHKIAHGHAVMIGIIYQFIVANILFN
                     SNHDIQHYINYLTKLGYPLETITDIDFETIYQYMLSDKKNDKQGVQMVLIKHFGDIVV
                     QHVDQLTLQHACEQLKTYFK"
     gene            complement(21098..22264)
                     /gene="aroC"
                     /locus_tag="RPH49_001869"
     CDS             complement(21098..22264)
                     /gene="aroC"
                     /locus_tag="RPH49_001869"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDY5125010.1"
                     /translation="MRYLTSGESHGPQLTVIVEGIPANLEIKVEDINKEMFKRQGGYG
                     RGRRMQIEKDTVEIVSGVRNGYTLGSPITMVVTNDDFTHWRKIMGAAPISDEERENMK
                     RTITKPRPGHADLVGGMKYNHRDLRNVLERSSARETAARVAVGALCKVLLEQLDIEIY
                     SRVVEIGGIKDKDFYDSETFKANLDRNDVRVIDDGIAQAMRDKIDEAKNDGDSIGGVV
                     QVVVENMPVGVGSYVHYDRKLDGRIAQGVVSINAFKGVSFGEGFKAAEKPGSEIQDEI
                     LYNTELGYYRGSNHLGGLEGGMSNGMPIIVNGVMKPIPTLYKPLNSVDINTKEDFKAT
                     IERSDSCAVPAASIVCEHVVAFEIAKALLEEFQSNHIEQLKQQIIERRQLNIEF"
BASE COUNT         7227 a         4021 c         3127 g         8053 t
ORIGIN      
        1 cttaattctt ctaattcttt tttaagttta tgattctctt ctgataattt tacaacttca
       61 ttattcatat cggccatttt ttgataatca gcaataatgt catctaaaaa tgcatctact
      121 tcttctcttc tatagccacg agccatcgtt ttttcaaaat ctttttcata aatatctttt
      181 gctgataatt tcaatgaaac atctgacatt ttttccacct cattagaaac tttgatcttc
      241 agaccactgt aagtcattga tgaatgctgt taattcatcg aacgtcacaa tatcacaagt
      301 atagtttgtt ttatccataa aatcaactaa catctgcttg aagaacttag gactcgcctc
      361 ttgttcctca tcataaatga gcaatgtttg gtccgaatgt tcaagcataa attgatctgc
      421 ttgtttaaat tgaaaaggac cttgatacgg cgtatgaaaa atactatcaa cataatctgc
      481 atgcttaatt atgttggcat acttactttg attatgttca ttccactttt ctgtatgtcc
      541 ttggaacggt gtaattacag caaactttaa cgaatcatat gttcgttgta attcaataac
      601 aacttctgca gtccataatt ctatacccat ttgcccttgt attaacaccc attctaatcc
      661 ttcatccaac agttgttcaa ttttatgttt tataaattgt tttaaataat gtacttcagg
      721 tgcgtcatct ttaaaaatgt ttaattcgaa tgatttgtaa cctgttacat aaactgtttt
      781 aaccatgagt accctctttt gttacgccat ctaatatatt ttgtaaatca tattgaacac
      841 ttttaagctt ttcaataaat aactttcgac ttgttcgctt aaaatgacat tcgacagaaa
      901 gttgttcaat gttagcaatc agtagctcaa atttccttga attcatataa ggtacttcta
      961 taataaattc acgatgtaat ttgatctcat tgagcatgct atcaatatgt tcagtatatg
     1021 gctttacagt ttggtaaaaa tcatgatctt gttgttgtga tttcacattt tcaaaatttt
     1081 gttgcatgtt gttaacttca taaattagtg attcgactac atcattcatg aggacgcctc
     1141 ctacattttt taatttatca caatatactg tattcgtcat gttttaacac tctatataat
     1201 ttgatttaac tattttttaa atgtgttatc tgttaaatca agtaaatcta aaaacttcct
     1261 atataaatac aaaattttat cgtgtatgtt gttatacgat gaaaatactt ataatctaat
     1321 aaaatcattt aaatcaaata cacccctgct gattaacaac acatacttgt acttgcctca
     1381 aaaataataa ttactgatca tgattcgact tttataacaa aattcaaaaa tattgtaatg
     1441 agtattcatt tttataagca aaacttttca attaattaaa attgtgtgta aaattccaac
     1501 attaacggta aatgtattat aatattattg tgttaatgct gaaatcacgt taaaataagc
     1561 tttggtgtat tgtgtctttc gcatttatac taatttaagt ttggtgtttc actataatgt
     1621 tgtgtataat aaacaacgtt tactaccaaa cttgtgtggt gaaatttatg aattatccaa
     1681 atggtaaacc atatcgtaaa aatagtgcta tagacggagg gaaaaagacc gctgccttta
     1741 gtaatattga gtatggtgga cgtggtatgt cacttgaaaa agatatcgaa cattcaaatg
     1801 cgttttatct taaaagcgac attgcagtta ttcacaaaaa gcctacgccg gtacaaatag
     1861 ttaatgtcaa ctatcccaaa cggagtaaag ctgtgattaa cgaagcttat tttcgtacac
     1921 cttcaacaac tgattacaac ggcgtttatc aaggttatta tattgatttt gaagcaaagg
     1981 aaactaaaaa caagacgtcc tttcctttaa ataatattca tgatcatcaa gtcgaacata
     2041 tgaaaaatgc atatcaacaa aaaggtattg tgtttttaat gattcgtttt aaaacgctag
     2101 atgaagttta tcttttaccc tattcaaaat tcgaaatatt ttggaagaga tataaagata
     2161 atattaaaaa gtctataaca gttgatgaaa tacgaaaaaa tggttaccat attccttatc
     2221 agtatcaacc aagattagac tatctaaaag cagttgataa gttgatatta gatgaaagtg
     2281 aggaccgcgt atgacggaaa acaaaggatc ttctcagcct aagaaaaatg gtaataatgg
     2341 tgggaaatcc aactcaaaaa agaatagaaa tgtgaagaga acgattatta agattattgg
     2401 cttcatgatt attgcatttt tcgttgttct tttactaggt atcttattgt ttgcttatta
     2461 tgcttggaaa gcacctgctt ttaccgaagc taaattacaa gatccgattc ctgcaaagat
     2521 atatgacaag aacggagaac ttgttaaaac attagataat ggccaaagac atgagcatgt
     2581 aaatttaaaa gacgtgccga aatcaatgaa agacgcagta cttgcaactg aagacaatcg
     2641 tttctacgaa cacggcgcac ttgattataa acgtttattc ggtgcaattg gtaagaactt
     2701 gactggtgga tttggttctg aaggtgcctc aacattaaca caacaagttg ttaaagatgc
     2761 atttttatca caacataaat ctattggacg taaagctcaa gaagcatact tatcatatcg
     2821 tttagaacaa gagtatagta aagatgatat cttccaagta tatctaaaca aaatttacta
     2881 ctctgatggc gtaacaggta ttaaagctgc tgctaagtat tactttaata aagatttaaa
     2941 agatttaaac ttagcggaag aagcttattt agccggttta cctcaggttc caaacaacta
     3001 taatatttat gatcatccaa aagctgctga agatcgtaaa aacactgttt tatacttaat
     3061 gcattatcat aaacgcatta cagataaaca gtgggaagat gctaagaaaa tcgatttaaa
     3121 agcgaactta gtaaatcgta ctgctgaaga acgtcaaaac attgatacaa atcaagattc
     3181 tgagtataat tcatacgtta actttgtaaa atctgaatta atgaataata aagcattcaa
     3241 agatgaaaat ttaggtaatg tattacaaag tggtattaaa atttatacaa acatggataa
     3301 agatgttcaa aaaacattac aaaatgatgt tgataatggt agcttctaca agaataaaga
     3361 ccaacaagtt ggtgcaacga ttcttgatag taaaactggt ggtttagttg ctatatctgg
     3421 tggacgtgat ttcaaagacg tcgttaacag aaaccaagca acagatccac accctactgg
     3481 ttcatcttta aaacctttct tagcgtatgg acctgccatt gaaaatatga aatgggcaac
     3541 aaaccatgcg attcaagatg aatcttcata tcaagttgat ggctctacat ttagaaacta
     3601 cgatgtgaag agtcacggta ctgtatcaat ttatgatgct ttacgacaaa gtttcaatat
     3661 cccagcttta aaagcttggc aatcagttaa gcaaaatgct ggtaatgatg cacctaagaa
     3721 attcgctgcc aaacttggct taaactacga aggcgatatt ggtccatctg aagtacttgg
     3781 tggttctgct tcagaattct caccaacaca attagcatca gcatttgctg caatcgctaa
     3841 cggtggtact tataacaacg cgcattcaat tcaaaaagta gttactcgtg atggtgaaac
     3901 aatcgaatac gatcatacta gccataaagc gatgagtgat tacactgcat acatgttagc
     3961 tgagatgcta aaaggtacat ttaaaccata tggttctgca tatggccatg gtgtatctgg
     4021 agtaaatatg ggtgctaaga caggtactgg tacttacggt gctgaaactt attcacaata
     4081 taatttacct gataatgcag cgaaagacgt gtggattaac ggctttacac ctcaatacac
     4141 tatgtcagtg tggatgggct tcagcaaagt taaacaatat ggtgaaaact catttgtggg
     4201 acatagccaa caagaatatc cacagttctt atatgaaaat gtgatgtcaa aaatttcatc
     4261 tagagatggc gaagacttta aacgtcctag ctcagtaagt ggtagtatcc catcaatcaa
     4321 tgtttctggt agtcaagata acaacactac aaatcgtagt gcacacggtg gtagtgacac
     4381 atcagcaaac agcagtggta ctgcacaatc aaataacaat actagatctc aacaatctag
     4441 aaacagcggt ggattaacag gtatattcaa ctaatccact caacataaaa tcctcagtta
     4501 taccatattt atggtgtagc tgaggatttt tttataagta ttcatacgct attgctatat
     4561 tagtagaaac cgtaaaatca gacattcaca tacattttga aacatctaaa tagtctttca
     4621 tattcacatc tttagctatg taaaattatt gaatttcaat aagtggttgt tcccattttt
     4681 aaaattatga ttatattttc tcataatcat cttagacgtt attttaaatt gatatgttta
     4741 tcaattccct gagtacgtta atcagtgaaa tatcaacatg tttgcaacat attttcacaa
     4801 tcatagatat aagaaatcca cctacgattc gaaatagata tcttaaagca tacctcaaga
     4861 tatccattat gatgtagatg gacagttttt atattaagac gttgtaatga cacgacatct
     4921 aacataaata caaatatgtg tgcatgaatt agtcttatat ctttttaaca ttagaaaatg
     4981 atcaaacttg tctatacctg cttattcttt aaccttgttt gataactagc attcatttta
     5041 atcaattcag ttttaaaggt cttcatttgt cgatagccca taaaatgata tttacgttca
     5101 atcatataat catatctttc tttaaaattc attggcacaa caggatattg atttaaatta
     5161 tcaaaatcaa tattgccagt gatgtcatta acctgcttaa aataatcaat aattttacta
     5221 tggtattcat ccaagtaagg ttttgcttca ctagaaccta atgtcttatt tttggcaaat
     5281 acatcaatct cttgttctaa attatcaaat acctcttttg taatatttgt catattatca
     5341 cgcttctttc aaactagctt tataacgttt ttgtccttct ctacaatctt ctaatagtgg
     5401 acaaatatcg catttaggtt ttcgggctaa acagtggtat cttccaaaga aaatgagttg
     5461 atgatggctc ctattccatc tatctctagg tatgacagaa cataaacggt cttctacctg
     5521 tctcacatta tctttccaac gattaatacc taagcgttta gaaacacgtt ctacatgcgt
     5581 atcaacagct aacgaaggtt catcaaatgc tacactcatg actacattag cagttttacg
     5641 tcctacacct gctaaacttt ctaattcctt atgtgtttgt ggtatttctc cattaaattg
     5701 atcaatcaaa gattgacaaa gtttcttaat attcttagct ttgttacgat acagaccgat
     5761 agaacgaata tcattcataa gttcttcatc actgactgcc aaataatctt caggcgtttt
     5821 gtatttttta aacagctcag ttgttactct atttactaga acgtctgtac attgcgctga
     5881 caataataca gcaatagtta attcgaacgg attatcatgt tttaattcac attctgcatc
     5941 cggaaacata tttgctataa catcaatcat ttctaatgct tttttcttac ttaccatcaa
     6001 ggttctcccc gtttaaccaa tcaaatttag gtaccgtttt aactgtgtgc gtcattttcg
     6061 gtttattgaa tttttctctt atttttctag aatcgtcaat tgttttaaca ttgtttttct
     6121 tccaattaag taaaatacga tccatatatt taaagctaag tttattcaaa ctattcgcct
     6181 cgtctaatgc cgcttgtata attgcagtat cgtgtttatc aacatcaatc cattgattta
     6241 acgtttctat ttcatatgga gataacggcc ttgcaaatgt atcctctaaa actctaaata
     6301 attgtttaaa tttttcttta ctattttgct ctttcgtttc catactttgt tgcttcaata
     6361 tatgacttaa tttttcgaaa aaaggatcta gattcatata ttcggtaaat ctaccttctt
     6421 catctttttg aacttgtaat tctagcaatt cacgttgtat caaattttga ataaccattg
     6481 taatatcacg tggttgcata gttgagccct tctgaagtaa ttcaattgaa ggctgtttat
     6541 ttgatgtttc ggaagcataa atcaatttaa gcaaaatgac taaatcttgc tcatctaaac
     6601 ctaagtcact gtaatggtct aataattctc ttcgtatcac tacaggtctt gcttttaatt
     6661 gatatttatc catgttcgtg ccccctttta aatttaacca ttacttaata gtataaatca
     6721 ttttctttaa ttttcgacta aaatgcttaa tatatttaac tagtagcaaa caaattttaa
     6781 ataacagtat tttttaaaac tagattttaa caatgaactt tatggataat cagatgaact
     6841 atttattttc caaatatagt tactaaacaa aagtttgttc atgattaata taagccgtta
     6901 tcaatcttca ttttccaagc ataaatcgcc cagctattaa tataggctgg acgattcttt
     6961 ttattatcat aatataaata ttaagtaacg atcctaaaac ttatggatat aaacggttta
     7021 ataatcttgg gaatggcgca gtttcacgaa cgtgttcaac accagaaatc catgctactg
     7081 tacgctctaa acctaaacca aatccacagt gtggcacact accataacga cgtaagtcta
     7141 agtagtaact atatgcttct tcgtctaatc catgttcttt aacgcgttgt tctaacaatt
     7201 ctaagtcatc cacacgttca gatccaccta taatttcacc gtatccttca ggtgcaatta
     7261 agtctgcaca taatacagtt tcttcatttt caggatttgg ttgcatatag aaaggcttaa
     7321 ttttagttgg ataattagta ataaacaccg gtaaatcata atgattagca atggctgttt
     7381 catgtggcgc accaaaatct tcgccccatt caatatcatc aaagccttct gcttttaaga
     7441 attcaattgc atcatcatat gaaattctag ggaatggtgt cgcaactttt tcaagttttg
     7501 atgtatcacg ctctaacatt ttcaactcta gtttacaatt ttctaaaact gattttacaa
     7561 catgtgttac atattgttct tgaatttcta aactttcagc atgatttgtg aaagccattt
     7621 ccccttcaat catccagaac tcgatcaagt gtctacgtgt ttttgatttt tcagctctga
     7681 aagttggacc aaatgaaaat acttttccgt gtgccatagc tgcagcttct aagtataact
     7741 gaccactttg agataaaaac gcatcttgat caaagtattt agtatggaat aattcacttg
     7801 taccttctgg cgaacttgct gtcaaaattg gtggatcaac ctttgtaaat ccatctttgt
     7861 tgaaaaattc atacgttgca cgaataactt catttctaat tttcattaca gcatgttgtt
     7921 ttttagaacg taaccataaa tgacggtgat ccattaagaa ttctgtacca tgatttttag
     7981 gtgtaatcgg atagtcatgc gcttctgaaa taacttcaat tgatttcact tgcatttcgt
     8041 atcctaagtc agaacgatta tcttctgtaa ttgtgcctgt aacatataga gatgattctt
     8101 gagtaatttc tttcgcaagt ttgaatacct cttcatcaac ttctgattta actactacgc
     8161 cttgcataaa gcctgttcca tcacgtaatt gtaaaaaggc gattttacca cttgaacgtt
     8221 tatttgttag ccaagcacca attgtaacgt cttggtttaa atgatctttc gcttgtttaa
     8281 tcgttgtttt cataaccatt ctcctattta ttttttcgtt atacaatact cattcatttt
     8341 aacaaaatcc gctttcaagt tctagaacta gactaaaaga taacgtgtaa atggtaatga
     8401 tttaagcaca gatttgaaca ttaatttata ttaagacaat acaatcatca gtttcagaca
     8461 aaatatataa taaatcctca atattattag tatgaaggtc gttttttgtg ctaacattca
     8521 agtttaatta taaaactcaa attttgacga ccaaacaaaa attcttgtaa cagaacatag
     8581 cacatgtcat gtcacaagaa ttttactttg tatttcactt tttctttttt tgaatttgtc
     8641 ttaataattt tccaaactgt tgaatgtcgc cttttttctg acgataattt tcaagtgttt
     8701 gttcaaaaaa gtttttataa ttactgttta tgagtcgatc atcaaatgaa actattatgc
     8761 cgcgatcatt ttcatttcta attaatcttc caagtccttg tctaaaacgt gtaactgcat
     8821 caggtaatac atattccttg aaagttgaag tgaattcaga atccataagc caatattttg
     8881 cattatgctt gttcataaac ggtaacttcg ctatcatcac acatttaata ccatttgctt
     8941 gaaaatcaaa accttcaaaa aatgttgacg taccaagcag tatggcctta tcaaaattat
     9001 taaactgttg tactatttta taattttggt tctgctgttg tgttaataca acataatctt
     9061 caaattctgg caattcattt agcatatctt gtaccatatg catcatttta taactcgtaa
     9121 ataagactaa acattttgat gacgttatag tcgtatattc aataatatag cttacaatcg
     9181 atgctacata ctcatctata tttttatatt gataagatgc tacatcactc ggtataaata
     9241 cacttgtatt ttttgcactt tgtaacgacg tgttaacttc aaatgtatta aagtgaacat
     9301 ctttgttgaa taactgttta aaagcttcaa acgaatgatt aaattttaaa gtaccagata
     9361 taaaaatgag tgatttaaat ttttccaata cttgtttcgt taatacatct tttacagcgt
     9421 aatctttcac atataaacgt attgttgatt tttgagataa atttttaatt gaaatgaaac
     9481 tagtatgtcc agcttttaaa ctttgttcga tatttttaaa tttatctttt aaatacaaca
     9541 actgtttccg taatgattta actgttttat gactaatgcc attgaatatt tctagcgttt
     9601 tatttaactt atcgataatc gcatgtaaat ccttcaaaat gtcttttgtt tcaaaagtaa
     9661 atacattatg gaagcgatga atatcatcat cataaacatc agaatcattg ataatcgtaa
     9721 atatcgttga aaacaattgc tcatttaact catgaatctc attcatacta gccttcaagc
     9781 caaaaatatc aattggtgca atatctaact tttccaaaat tcgctgcttt tccagttgat
     9841 caattgcctt taacaatttt tcattttcgt ttttaccaat caaaccaagc tgatatttaa
     9901 tatcagcata actcaactca tttgtcactt gatttaaggc atagtctggt aagcgatgtg
     9961 cttcatccac tatacaatca tcaaacaatt gatatattga attttcaaca tcagaatgaa
    10021 ttaaatgtgc atgatttgta ataccaattt gaatgttctg tgcatttcgc ttaataaaat
    10081 tataataatg gacatcgtga cgtgccggta catatgtttc aattttctgg tcaaaataca
    10141 tcttttgacc accttttaaa tttaattcct gtatatctcc ggacggcgtc tctgtaatcc
    10201 aaatcagcaa ttgcattttc aagatattca cttcgtagtt acttgtgtca tcttttaaaa
    10261 tttgactaat aagccccaat gaaatgtaat cacttttact tttaatcaat agtgcattaa
    10321 ttttaaaatt taacgcttca ttcattgctg gaatatcttt ttctaacaat tgactttgca
    10381 gtaatttggt attggtagaa atcataacat gctttccagt ttcaatatta tacatcaagg
    10441 ccgcaagtaa atatgctaat gatttaccac tgcctagtga tgcttcaatc attgcttttt
    10501 cactatgcat gagctgatct aatatagttt ccgctaaata taattgctgc ggtcgatatg
    10561 ttaagccaag ttgatctaca gctttgctat ataaagactt caagctgcca ttataatttg
    10621 ttgtcggctt tttaaaatca acttgcttac gatagataat ctgttcgaac ttttcgtacg
    10681 atttatccaa tggctttgca tcatattgcc taaccatctc aaagaaaata tcatacaaat
    10741 cgtatttcaa ctgtttactt aaataatata attgctttaa agtatctaac ggtaactttt
    10801 caaatttttc aaaagctaat atcatcaatt tagcagtagt agcggcatcc tcgtcagctc
    10861 gatgggcatt tgctaagtta ataccatgtg cttctgctaa ttcacttaat tgataacttt
    10921 tatctgtagg aaaagctatt ttaaagattt ctagtgtatc tataactttt ttgggacgat
    10981 attgaatatt acaatcttta aatgcctttt taataaaatt taaatcaaaa tctacattat
    11041 gagcgacaaa aatgcaatct tttatcttat cgtagatttc ttgtgcaact tgattaaaat
    11101 atggcgcttg ttgtagcata ttttcttcaa tggatgttaa cgcttgaatg aatggcggaa
    11161 tctctaaatt tgttctaatc atagaatgat atgtatcaat aatttggtta ttgcgcacaa
    11221 acgttatacc aatttgaatg atatcgtcaa aatctaattg gttgcctgtt gtttccaaat
    11281 ccacaacggc ataggttgcc atacccatag ctatctctcc ttgctttagt gttaaaaatc
    11341 tatatctgca ctaattaaac ggtgtgattc acccgcttca tctctaacaa ttagatagcc
    11401 atcgtaatct aaatcaattg cttgtccttt aaactgttta tcattttctg taaatagcaa
    11461 cgttctattc caaatattag aagctgcaat atattcttca cgaatttcag aaaaaggtaa
    11521 cgttaaaaat tgattatatc ttttttcaat ttcttgaagt aatctctcta aaaattgata
    11581 tctatctaat ttatttttat catttaattg tatacttgtt gctctatgtc taatactttc
    11641 atcaaagtca tctagttgtt gcgtcaaatt aatacctata ccacatatta ttgcttctat
    11701 accatcatta ttagcaacca tttcagttaa gaaaccacac actttaccat tatcaatata
    11761 tatatcattc ggccatttca ctttgacttc atcttgacta aaatgttgaa tcgcatctct
    11821 tatccctaat gcaataaata aattaaattt agatatcatt gagaatgcaa cgttaggtct
    11881 taacacgaca gacatccaaa gtccttgccc ttttgaagaa ctccaatgtc tattaaatcg
    11941 cccacgacct ttcgtttgtt catcactcaa gataaaaaat gaagattgat ttccaacaag
    12001 tgactttttc gcagcaagtt gtgtagaatc tattgaatcg tatacttcac taaaatcaaa
    12061 caaagcagaa ctttttgtat attggtctat tataccttga taccaaatat ctgggagctg
    12121 ttgtaataaa tgccctttat gatttactga atctatttta catccctcta attttaattg
    12181 gtcaatcact ttttttactg cagtgcgcga tatattaagt gattccgcaa tgctttgtcc
    12241 agatatataa ttcggtttat ttttatagag taattgaagt acatcttgac tatattttga
    12301 catgattatc cacccatttc aaaatttcag tttcttcgtt gcttacttta cctgttacaa
    12361 tcgctatctc aatttgtctt agcacatctt ttaaccatgg accacttttg gcatttaaat
    12421 gtgccataag tacaccgcca ttaaccatca tgtcttttct attatgcata ggtaaacgat
    12481 gtaatgtttc atcaatcgtt tgaaggttaa cgattaatgg ttcatgtcct tgaatatcat
    12541 ttgcctttaa cacgtctgct gcaaccatta catttttaat gagattcgta tcataatcat
    12601 aaacaaacat ttttaattgt tcttttgtaa taatacttgg taatgcattc ataatttgaa
    12661 tatattgatt gatatctttt acttgtcggt tacttagctt taaaggcttc aatgagtaat
    12721 taatatcaaa tttaactgat gctatagcaa tcaataattc taaatcaatt gcttcagtca
    12781 cattaatttg attcatatca agatgttcga aatatggcat ataattaaat gctttcagcg
    12841 attttaaatg attaaaactc tcttcaacat taatacctcg cattaattta gttagttcaa
    12901 tcactatacg ctcaattgat aaaaatttaa tatctgccat ttgtgtacgc atcgcttcga
    12961 atgtttccgt tgcaatatca aatgataatt gtgactggaa tcttaaacat cgaatcatac
    13021 gtaaagcatc ttcttggaat cgttcctcag ctatacctac agttcttatt attcgattat
    13081 taatatcttg ttgaccatca aaataatcat acaatttgta tgctgtatcc attgctatcg
    13141 cattcatcgt gaaatctctt cgttgcaaat cttcgtataa atcacgaaca aatgtaacac
    13201 cacttggtct acggtgatcg acataatctt cttcagcccg gaatgttgtc acttcataat
    13261 tttcatcatt aaaaactaca tttatcgtgc catgttcttt acctacaggt atcgtatgac
    13321 taaagattga ttctatttca tccggcgttg cacttgttgt gatatctata tcatgaatat
    13381 ttcttcccat gacataatct cttacagagc cacctacata atatgcttca aaaccattgt
    13441 cttgaatttg ttctaatata ggccttgcct gttcaaataa tgatttatcc atattattac
    13501 tcgcctttac ttttgttatg ttcatttagc attttttgat aataatactc atattgatct
    13561 gtaatgagtt ctgatccaaa acgttcagca atatctgcta gcatgttttt ctgaagtttg
    13621 ttgtataacg ccttatcttc aagtaatcgg atagcatagt cactcgctga atcacaatca
    13681 cccacatcta caacaaatcc agtttcacca tgtttaataa cctctttaat tccaccggca
    13741 tttgaaccaa ttggaacgac gcctgttttc atagcctcaa gtaaagttag tccaaagctt
    13801 tctttttcac ttaataataa tactaagtca gataattgat aaaattcact tacgcaatct
    13861 tgcttcccta aaaataaaac atcctcttct acgtttaact ctttcgtcaa ttgacgcatt
    13921 ggcactaatt caggaccatc tccaagtaaa attaatttac taggtatctt ttcacgtact
    13981 tttgcaaatg tttctataat agtatctatg cgttttactt gtctaaaatt cgatacatgt
    14041 attaacactt tttcatctgg tgctatacca aattgtgatt ttagtgctgt gttatgttta
    14101 gttggaaact cattttcacg tacaaaatta taaatcggta taatttcttt gttagtttcg
    14161 ataatttcat gtgtttcttg cgctaaagat ttactcacac ttgtcacaat atcacttttt
    14221 tcaatgccaa atttaattgc accttggagt gaatgatcat agcccaaaac agtaatatca
    14281 gtaccgtgta gcgttgtcat aatttttata tctttacctg acatctcacg agctaaaata
    14341 ccacaaattg catgaggtac agcatagtgc atatgcaaca aatcaagatc atattcttta
    14401 ataacttcag cgattttagt acttaacgta atatcatacg gtggatattg aaatactgca
    14461 tattgattca cttcaacttg atgaaaaatc atattcggta atggttttct tattctaaac
    14521 gggatatttg aagtgataaa atgtacttcg tgacctcgct ctgctaattt aattcctaat
    14581 tctgtggcaa taattccaga accacccatg gacgggtaac atgttatacc tatcttcatt
    14641 cgcttgccca tcctttcttt ctatttctat tattctcgat gcgtagataa ttgtttaaat
    14701 ttaagtttat agtaatgttg agtttataat ttcaaatatc taaaaaacag gtgttgtata
    14761 tataatcatt catctagtta tacttacttt aaaaataata tgatttcatg cgatgcaatt
    14821 cattgatgga tgtttttaat cttaatcaaa tccaaataaa gcatatattt ttatattcac
    14881 tttctttcga atcgattttt atctcttgta ttaaactttt ccatagtttc attaaagctc
    14941 tctgtcatat ctattcccat tgaattcgct aaacataaca acacaaataa attatcacct
    15001 aattctgctt taatcgtatt tgcttcctct gaatctttct tctttttttc accataggta
    15061 tgatttattt cacgtgcaag ttcgcccact tcttcagtca atctagctaa gttagctaat
    15121 ggtgaaaaat atcctgtttt aaattgtcca atatattcat caacttcacg ttgcatttct
    15181 accattgatt tcatttctac gttctcctta tattgcattt ctaatatagt atatatcaat
    15241 ttgaagtctc atgcatgttt agtgcaatct actgactcta gctaaactag atgacaagtt
    15301 gtttatttta gaagtttaat aattcagttt atataaatgt aatgcattcc taactaaatt
    15361 aaatcaattg aaattgggat tataacttta tgatacgtac tactacaata aaataatata
    15421 gtgaataatc taccatgaga aaaataagca caaaaaaact agcaaccaca caaaaatgtg
    15481 attagctagt taataagtgt ctaatttaag ttaattgtta atctataaga ttaatcactt
    15541 gaacgcgcaa tcaaaataat acgtacaagc tctgctacag cgacagcagt tgctgcaaca
    15601 taagtcattg ctgctgcaga taatacttta cgcgcatgct tgtattcttt ttcatttaca
    15661 atgttcaatg ccgtaatttg tttcatcgct cttgaactcg catcaaactc aactggtaac
    15721 gtaacaattg agaataatac cgctaatgac attaaaccag caccaatcca taaagcagtt
    15781 gaaccaaatg cactacctat cgctgttaag ataataccta acatgatgat catataactt
    15841 aatgaactcc ctaggtttgc aacaggtact aatgctgctc tgaatcttaa gaaccaatat
    15901 ccttggtgat cttgaatggc atgaccaact tcgtgggctg caattgcagt tccagcaact
    15961 gatggtctgt catagtttgc aggagatagt gaaacaactt tctttttagg atcgtaatga
    16021 tctgttaaga atccttcacc tttaacaact tcgacatcat aaataccgtt tgcatgtaaa
    16081 atttctaatg caacttcacg acccgtttta ccactagttg atctaacttg tgaatatttc
    16141 tcatagttag atttaacttt gtgttgtgcc cataaaggaa gcaccattaa tattacgaaa
    16201 taaattatca tagtaaaaat tgaagacaat aaactcactc tcctttataa atattttact
    16261 gtcatttgcc gtttttatca aatcatttac actttaataa tttgtttaat tcaatataaa
    16321 gcaaaagtcc aaaaacactt agacaacatg ataatacacc aatttgccac acatgtgtag
    16381 ttataaaatc ataatatgga aattgaaggt gaaaatagtc aatataatca ttcaaaaata
    16441 cccaaatcat cgctacactg attccaatca tagaacgttt aaacctagga tagaagtaaa
    16501 ttgcctgaac agccattata ctgtgggaaa acattaatac caaaccattt actgtaatat
    16561 caccttgttc aataataaat aatatattca ttataactgc ccaaatccca tatttgaata
    16621 atgttacaaa tgccagtgca tcgataatac tattttgttt ttgaattaat atcaatgaga
    16681 tagaaataac taagtataat attgcagttg ggctatctgg aacaaaaatc ttaaaatgcc
    16741 acggcgtatg acttaattgt tcaccatacc atatataacc ataaatcatc cctaatatat
    16801 tacaaatgag tagcatcatt aaccaagaac gttgataaag tgtatattgc caaaatgtat
    16861 taatcgtcat ctgctaagtc ctcaaattga ttatgtttat ttactagctt gagtgtattt
    16921 aaaatttgcg ttagttgata aaaacgttgc ttttcattca tctgtaaact taaatcaata
    16981 ttgtgtaaca agtaatctat taataacgca tgtttatgcc gatctatagc catactattt
    17041 aagtcatgaa gataagtttg ataactgggc gattccgtta gttgagcaac tattaaatca
    17101 tctagccttt gctcacgctt tgacacgttt gcgaagtgaa tttgaatatc aaaagcacag
    17161 ttatgattag cgatataatc aaatatttca tttgtattca ttaactttat attacgctta
    17221 gtaaattgaa ttgcagaagc gtgacttccc acttctgcaa tttctaatgt ttcatgatga
    17281 ttaatttttg tatctacaaa atgaatgttt gccaatttcg cctcattcac ttttatatag
    17341 ttaagcaccc aaactgcaat acgcgactta aatcgatatt gaaaaagtaa atattcaata
    17401 aaactttctt taatttgatt gagtgtctct gacatcaaat accccatttt aagattgcaa
    17461 tcttgataat tcgtcatgcc aattttcgtt acttggctct agttccaaca attgatttaa
    17521 aatagtaatt gcttgttcct tttgaccaat ttcaattaaa tagaaataat aatcactcat
    17581 aaaatcaata tttgttttca tcgttggata tgctaattca aagaaatgtt gagcttcttt
    17641 atctcgctct tcttgaccat aggcgaacgc taaatgccac atgaatgtag gatccaaatc
    17701 ttcttcatct acatatgtta ataattcaat gattgcttca taatcttctt cattacgata
    17761 taaatcgctt aaaatcaata aaggttcttg gtaagcatta tcaacctcta atgcttgttt
    17821 taacaataat acaccttcat tagcatcgcc gtgttctatt tccaaacatc cagttgtata
    17881 cattaactct ttataaaatt gacttagtcg taatccttct ttacccgttt caatagcatc
    17941 tggataattt ttttcatttt catataatga ttgtaaatac aagtagcctt gaatataatc
    18001 aggatcttta gaaagtaatg tagtcattat tttaattgct tcttgagtga tgtcattttt
    18061 atcgtaagaa atggcttttt tgagataatc ttctgaagtc atttcatctt cattaatttc
    18121 atcgtataag cgaatcgcat cactatagtt accactttgt aaactacaat ctgccatacg
    18181 agagaataag tttacaccat taacttgata ttcaccagtt tctaaaacgg tttcgtattc
    18241 agaggtagca cgtaaatatt gaccatcata atataacatt tcagccaatg caaaatggat
    18301 tattggatca tttggctcta gttcaagtgc ttcttgtaat ttatcaatag caacttccat
    18361 catattaatt tgttgatata aatctgcttc taacatcaac ttttcaggtg atggttcaac
    18421 ataacttaaa tattctaacg cttcgtcagt ttgattttca gacattaaac cttcaataaa
    18481 ataaatcagc aattcacttt cgtctggata tttgtgatat aacacgcgga atacttccaa
    18541 accttgtggc attaatccaa aattgtaaag tgtctctcct agaataaata atgcgtcatc
    18601 gttgtcagta gttattgctt cattaacacg agagtctaaa ttttctagtt tttgtagatt
    18661 gatatcgtct attaatttat agatatcttc cattttatat tatccctcat tttctaaaag
    18721 ctttagtttt ggtaaaaatc ctggaaatga tacatttacg gcatcaaatt gtttgatttt
    18781 gactggctcg cttgaaagta gagaagcaac tgcaagcatc attcctattc gatgatcagt
    18841 taaactatca actgttgcat ttgttttaaa ttctgacgga tgaataatca atccatcatt
    18901 agttggttgt aattcaaacc ctaacaagtt taacatatca gccgttgtat caattctatt
    18961 tgtttctttt acttttaatt cctcggcatc tttaattgta ctcgtgccaa ctgcttgtgt
    19021 acaaagtaat gctattacag gcagttcatc aattgctttt ggcactaatt ctccttcgat
    19081 tgttattggt tgaagcattg gtgtgtattg tatacgaata gaagcagtag gttcagcacc
    19141 agttgtttga ttgaaaagtt gaatattacc gcccattttt tcaacaatat caataatacc
    19201 tgaacgtgtt ggattgattc caacattatg aattgttaca tcacttcctg gtgtgataag
    19261 tgctgcaaca ataaagaacg ctgcagatga aatatcgcca ggaacatgaa aatctgcagg
    19321 tttaatgtat cgaattgctt caggggttgt agtaattgat aacccttctg cttcaattgg
    19381 aatattaaaa tgtctgaaca tcgtctcagt atgatttcga cttacatcta attctttaat
    19441 gatggtcggt tccttagaaa atagacttgc gaataagatg gcacttttca cttgtgcact
    19501 tgccacttcc atcttgtaat taataccttt aattacagac ggtttaatga ttaatggggt
    19561 gtaattgtct tcaattcctt caatatttgc attcatactt tttaacggtc ttaaaacacg
    19621 atccatcggc cttttaccta tggaaacatc tccagacaag acactttcaa tacctaaacc
    19681 acttaacaaa cctgccaata atcgtgttgt cgtaccagaa ttacctgtat acaatacttg
    19741 atgtggcgtg ttaaaagatt gatatcctgg ggaagtcaca actaattttt catcatcttc
    19801 tttgatttct acacctaaca gtcggaaaat gtccatcgta cgacgacaat cttcgccaag
    19861 tagtggctta tatatagtag atacaccttc agctagcgac gccaacatga ttgcacggtg
    19921 tgtcattgat ttatcgcccg gcacttctat ttcgcccttt aacggacctg aaatatcaat
    19981 gatttgttca tttaccattt cattcaccta cttaaaatat gtttttaatt gttcacatgc
    20041 atgttgtaat gttagttgat caacatgttg tacaacgata tctccaaaat gtttaatcaa
    20101 gaccatttgt acaccttgct tatcattctt tttatcactt agcatgtatt gatatatcgt
    20161 ttcgaaatct atgtcggtta ttgtttctaa aggataacct aatttcgtta aataattaat
    20221 ataatgttgg atatcgtgat tagaattgaa caatatattc gcaacaataa attgatatat
    20281 tatgcctatc attacggcat gaccgtgtgc aattttgtgg ttatactcca cggcatgacc
    20341 aaatgtatgt cctaaattta aatactttcg aacaccttgc tctttttcat cagcaacaac
    20401 gatatttaat tttgtttcaa tgcctttagt tatatattta tcaattccat ttaatgattg
    20461 taatgacgct cgatctttaa aatgttgctc gatgtcatgt gtagcagatt taccatttaa
    20521 taaggcatgc ttatatactt ccgcatagcc actcaatatt tcatcaaatg gcaaagtatt
    20581 taaaaagtct aagtcataaa ttacagcatc tggacgataa aatgcaccga taaggttttt
    20641 accttgcttt gagttaatac ccactttacc gccaacgcta gaatcatgcg ctagtatagt
    20701 cgttggcact tgtataaagt gaacacctcg taaaagtgtc gccgcaataa atcctgcaaa
    20761 atctcctgtc gcaccaccac caacagctat aatcgctgta ttacgcgtta catgatgtga
    20821 caaaatgtat tctaatgttt cttgatattg ctcaaatgtt ttcgtctttt caccagctgg
    20881 aataataact ttatgtacat ttccaaaaga taaaatatca ttaaatttat cagcaaaata
    20941 ttgatttaca tgctcgtcaa ttaatataaa actttgatca aactgatcaa tatacgtgct
    21001 aatatggtca attgcaccat gttcaacaaa tattggataa ttgtttgaag gataggttgt
    21061 ttgtaatttc atgatcacac ctcaattgtt cttgttgtta aaactcaata tttaattgtc
    21121 tgcgctcaat aatttgttgt ttaagttgct caatatgatt tgattggaat tcttccaata
    21181 atgctttcgc aatttcaaat gctacgacat gttcgcagac gatacttgct gcaggaacag
    21241 cacaactatc agaacgttca attgttgcct taaagtcttc tttagtattt atatcaactg
    21301 aatttaatgg tttatataac gtaggaatag gtttcattac accattaacg ataattggca
    21361 ttccatttga cataccgcct tctaaaccac ctaagtgatt tgacccacga taatagccca
    21421 attcagtatt gtagagaatt tcgtcttgaa tttcgctacc aggcttttca gctgctttaa
    21481 atccttctcc aaaacttaca cctttaaatg cattaatact aacgacaccc tgtgctattc
    21541 ttccatctaa tttacgatca taatgtacat aactacctac accaacaggc atattttcaa
    21601 ctacaacttg aactacgccc cctattgaat caccatcgtt tttcgcttca tcaattttat
    21661 cgcgcattgc ttgtgcgatg ccatcatcaa ttacacggac gtcatttcga tcaaggtttg
    21721 ctttaaatgt ttctgaatca taaaaatctt tatctttaat gccacctatc tcaacaacac
    21781 gactgtatat ttcgatatct aattgttcta ataaaacttt gcataatgca ccgacagcta
    21841 cacgtgctgc tgtttctctg gcagatgaac gttctaatac atttcgtaag tcacgatgat
    21901 tatatttcat accgccaact aaatctgcat gtcccggtct tggcttcgta attgtacgtt
    21961 tcatattttc tcgttcttcg tcgcttattg gcgcagcacc cataattttt cgccaatgtg
    22021 taaaatcatc attagtaaca accattgtaa tagggctacc taatgtataa ccatttctca
    22081 cacccgaaac aatctctact gtatctttct caatttgcat gcgtcggcca cgaccataac
    22141 caccttgacg cttgaacatt tctttattaa tatcttcaac tttaatttct aaatttgctg
    22201 gtataccttc gacaataact gttaattgag gtccatgtga ttctcctgaa gttagatatc
    22261 tcatacacac tcgctccttt catacttccg caataacatt ataatatgtt gttaatctta
    22321 tcacattcat tgtggattca taaatgtttg ttttcaagct taattaagaa aatggatgac
    22381 atctcatttt aaatgtcaga attatcttaa tattaaacga actaaaat
//
LOCUS       DAPSKH010000046        22028 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPSKH010000046 DAPSKH010000000
VERSION     DAPSKH010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 22028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22028
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.046"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            98..1594
                     /locus_tag="RPH49_001870"
     CDS             98..1594
                     /locus_tag="RPH49_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase FLP"
                     /protein_id="HDY5125011.1"
                     /translation="MTTKKLYFLSISIIILVAISIAIYITLNSNTKTRLTNDSQQQID
                     TIIEHDLQKGHIPGASILIVKNGKVFLNKGYGYQDVDKKVKASPTTKYEIASNTKAFT
                     GLAILKLAQEGRLNLNDAVSKHVPHFKMNYNGQNETITIKQLLAQTSGIPSDITSEDS
                     VTNKNNRLNDVTRAIMGDELHHKPGEEFEYSNMNYDLLGLIIQNVTKQSYTKYITNSW
                     LKPLNMTHTSFKQTNNKTKHDAIGYELQGSTPVVSKPEFNLWDTPSAYMMTSTEDLEH
                     WIKFQLNPPDKYKSLVQQSHKNLSSTIGEPNANAYASGWFTNNDEHLVFHSGTLDNFS
                     SFILLNPKQNYGIVVLANLNSEYVPKLVEHLNTQIVNHKRYSTVASMLNQYKNQFNIV
                     TVLMTTLILLAFIFSAYRAWQMRHGKIILRKSKLTTFSSWLTLCLCIAIALILYALPY
                     LILGSNNWSFVLTWLPIEIKLALITILIALFSTLIVILLFLHTKITKT"
     gene            complement(1685..2536)
                     /locus_tag="RPH49_001871"
     CDS             complement(1685..2536)
                     /locus_tag="RPH49_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDY5125012.1"
                     /translation="MSKIFVTGATGLIGIKLVQRLKEEGHEVAGFTTSENGQQKLAAV
                     NVKAYIGDILKADTIDQALADFKPEIIINQITDLKNVDMAANTKVRIEGSKNLIDSAK
                     KHDVKKVIAQSIAFMYEPGEGLANEETSLDFNSTGDRKVTVDGVVGLEEETARMDEYV
                     VLRFGWLYGPGTWYGKDGMIYNQFMDGEVTLSDGVTSFVHLDDAVETSIQAIHFENGI
                     YNVADDAPVKGSEFAEWYKEQLGVEPNIDIQPAQPFERGVSNEKFKAQGGTLIYKTWK
                     DGMNPIK"
     gene            complement(2860..3795)
                     /locus_tag="RPH49_001872"
     CDS             complement(2860..3795)
                     /locus_tag="RPH49_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDY5125013.1"
                     /translation="MKIAIAGSGALGSGFGAKLFQAGYNVTLIDGYTSHVEAVKQHGL
                     NITINGEAFELNIPMYHFNDQPDESIYDVVFLFPKSMQLKEVMEAMKSHIDNETIVVC
                     TMNGLKHEEVIAQYVAQSQIVRGVTTWTAGLESPGHSHLLGSGPVEIGELVDEGKENV
                     IKVAELLNEAELNGVISKDLYQSIWKKICVNGTANALSTVLECNMASLNESSYAKCLI
                     YKLTQEIVHVATIDNVHLNVDEVFEYLVDLNEKVGAHYPSMYQDLIVNNRKTEIDYIN
                     GAVATLGKKRHIEAPVNRFITDLIHTKESQRHAQD"
     gene            complement(4021..5421)
                     /locus_tag="RPH49_001873"
     CDS             complement(4021..5421)
                     /locus_tag="RPH49_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125014.1"
                     /translation="MDTSKQFRGDNRLLLGIVLGVITFWLFAQSLVNLVVPLQSTYSS
                     DVGTINIAVSLSALFAGLFIVGAGDVADKFGRVKITYVGLILNVIGSLLIIITPLPAF
                     LIIGRIIQGLSAACIMPSTLAIINEYYIGTRRQRALSYWSIGSWGGSGICTLFGGLMA
                     TYIGWRSIFVVSILLTLLAMYLIKHAPETKAEPIKGMKAEAKKFDVIGLVILVVTMLS
                     LNVIITQTSHFGLVSPLILGLIIVFICSLVGFVYYENKIKHPLVDFSIFKNRGYSGAT
                     ISNFLLNGVAGGALIVINTYYQQQLGFNSSQTGYISLTYLIAVLSMIRVGEKILSQHG
                     PKRPLLLGSGFTVIGLILLSLTFLPEMWYIVSSIVGYLLFGTGLGLYATPSTDTAVAS
                     APDDKSGVASGVYKMASSLGNAFGVAVSGTVYTVLAANLNLNLGGFTGMMFNALLAIV
                     AFLVILLLVPKNQTNL"
     gene            complement(5715..6410)
                     /locus_tag="RPH49_001874"
     CDS             complement(5715..6410)
                     /locus_tag="RPH49_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125015.1"
                     /translation="MEGNLLQQLFNYYVTNFGYLWDLFFKHLLMSVYGVLFAALIGIP
                     LGILLARYTKLSGFVITIANIIQTVPVIAMLAILMLVMGLGSETVVLTVFLYALLPII
                     KNTYTGIASVDANIKDAGKGMGMTRNQVLRMIELPLSVSVIIGGIRIALVVAIGVVAV
                     GSFIGAPTLGDIVIRGTNATDGTTFILAGAIPIAIIAIVIDVLLRFLEKRLDPTTRHR
                     KNQSNHRPQSINM"
     gene            complement(6410..7351)
                     /locus_tag="RPH49_001875"
     CDS             complement(6410..7351)
                     /locus_tag="RPH49_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5125016.1"
                     /translation="MKKIKYILVVFVLSLTVLSGCSLPGLGSKSTKNDVKITALSTSE
                     SQIISHMLRLLIEHDTHGKIKPTLVNNLGSSTIQHNALINGDANISGVRYNGTDLTGA
                     LKEAPIKDPKKAMIATQQGFKKKFDQTFFDSYGFANTYAFMVTEETAKKYHLETVSDL
                     AKHSKDLRLGMDSSWMNRKGDGYEGFKKEYGFDFGTVRPMQIGLVYDALNSEKLDVAL
                     GYSTDGRIAAYDLKVLKDDKQFFPPYAASAVATNELLRQHPELKTTINKLTGKISTSE
                     MQRLNYEADGKGKEPAVVAEEFLKKHHYFDKQKGGHK"
     gene            complement(7368..8003)
                     /locus_tag="RPH49_001876"
     CDS             complement(7368..8003)
                     /locus_tag="RPH49_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125017.1"
                     /translation="MIEFLHEHGGQLMSKTLEHFYISIVALLLAIIVAVPIGILLSKT
                     KRTANIILTVAGVLQTIPTLAVLAIMIPIFGVGKTPAIVALFIYVLLPILNNTVLGVQ
                     NIDSNIKEAGKSMGMTQFQLMKDVELPLALPLIIGGIRLSSVYVISWATLASYVGAGG
                     LGDFIFNGLNLYDPLMIVTATVLVTALALGVDALLALVEKWVVPKGLKVSG"
     gene            complement(8000..9226)
                     /locus_tag="RPH49_001877"
     CDS             complement(8000..9226)
                     /locus_tag="RPH49_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125018.1"
                     /translation="MLSIKHLTKIYSGNKKAVDDISLDIQSGEFIAFIGTSGSGKTTA
                     LRMINRMIEATEGQIEIDGKDVRSMNPVELRRNIGYVIQQIGLMPHMTIKENIVLVPK
                     LLKWTKEEKDKRAKELIKLVDLPESFLERYPAELSGGQQQRIGVVRALAAEQDIILMD
                     EPFGALDPITRDTLQDLVKTLQRKLGKTFIFVTHDMDEAIKLADKICIMSEGKVVQFD
                     TPDNILRHPANDFVRDFIGQNRLIQDRPNDKTVEGVMIKPITIQAEATLNDAVHIMRQ
                     KRVDTIFVVDSNNHLLGFLDIEDINQGIRGHKSLRDTMQQHIYTVQIDSKLQDSVRTI
                     LKRNVRNVPVVDDKQRLVGLITRANVVDIVYDTIWGDSEDAVQTEHVGEDTASSKMHE
                     QHTTNVKVRDIGDDKS"
     gene            complement(9553..9672)
                     /locus_tag="RPH49_001878"
     CDS             complement(9553..9672)
                     /locus_tag="RPH49_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125019.1"
                     /translation="MGFCPPVTMDACALLQKFDFCNNISHFRHFFAIKQPIER"
     gene            complement(9752..9861)
                     /locus_tag="RPH49_001879"
                     /pseudo
     CDS             complement(9752..9861)
                     /locus_tag="RPH49_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501207.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9896..10495)
                     /locus_tag="RPH49_001880"
     CDS             complement(9896..10495)
                     /locus_tag="RPH49_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family protein"
                     /protein_id="HDY5125020.1"
                     /translation="MSEKQSNEQVEAFLNKESQWQEEYKYLRALIFNETELEEAYKWM
                     HPCYTLNNKNVVLIHGFKNYVALLFHKGAILEDKYHTLIQQTEKVQAARQLRFENLTE
                     IQARSEEIKYYLAEAIKAEKAGKKVEMKKTEEYVIPKELEAKFEEMPQLESSFYKLTP
                     GRQHQYIYHIGQAKRSETRQKRVEKYINQILEGKGMHDK"
     gene            10676..12313
                     /locus_tag="RPH49_001881"
     CDS             10676..12313
                     /locus_tag="RPH49_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5125021.1"
                     /translation="MNKDKQLHNDKINLSQLVLLGLGSLIGSGWLFGAWEASSIAGPA
                     AIISWVLGFLVIGTIAYNYIEIGTMFPQSGGMSNYAQYTHGSLLGFIAAWANWVSLVT
                     IIPIEAVSAVQYMSSWPWHWAKPMRYLMENGSISTYGLLAVYLIIVIFSLLNYWSVKL
                     LTSFTSLISVFKLGVPMLTIIMLMLSGFDTSNYGHSASTFMPYGSAPIFAATTASGII
                     FSFNSFQTIINMGSEIKNPEKNIARGIAISLSISAVLYIILQSTFITSMPQSMLQHSG
                     WNGINFNSPFADLAILLGINWLAILLYIEAFVSPFGTGVSFVAVTGRVLRAMEKNGHI
                     PKFLGKMNEKYHIPRVAIIFNAIISMIMVTLFRDWGTLAAVISTATLVAYLTGPTTVI
                     ALRKMGPTMTRPFRAKILKVMAPLSFVLASLAIYWAMWPTTAEVILIIILGLPIYFFY
                     EYRMNWRNTKKQIGGSLWIIVYLIVLSILSFIGSKEFKGLNMIHYPFDFIVIIIVALI
                     FYYIGTTSSFESVYFRRATRINTKMHESLNNESKSSH"
     gene            12620..13972
                     /locus_tag="RPH49_001882"
     CDS             12620..13972
                     /locus_tag="RPH49_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylesterase/lipase family protein"
                     /protein_id="HDY5125022.1"
                     /translation="MKINTTGGQIYGITQDRLDIFLGIPYAEPPVHDNRFKHSTLKTQ
                     WSEPIDATEIQPIPPQPDNKLEDFFSSQSATFTEHEDCLYLNIWKQHNDQSKKPVIIY
                     FYGGSFENGHGTAELYQPAHLVQNNDIIVITCNYRLGALGYLDWSYFNKGFHSNNGLS
                     DQINVIKWVHQFIESFGGDANNITLMGQSAGSMSILTLLKIPDIEPYFHKVVLLSGAL
                     RLDTLESARNKAQHFQKMMLDYIDTDDVTSLSTDDILMLMAKLKQSRGPSKGLDLIYA
                     PIKTDYIQNNYPTTKPIFACYTKDEGDIYITSEQKKLSPQRFIDIMELNDIPLKYEDV
                     QTAKQQSLAITHCYFKQPMKQFLQQLNIQDSNAQLWLAEFAWHDTSSAHYRSAYHILD
                     MIFWFGNLQILSAHQYPITDHLKFLSRQMQNDLANFAKSGKMPWPIYHNERRYYRTYQ
                     "
     gene            complement(14034..15221)
                     /locus_tag="RPH49_001883"
     CDS             complement(14034..15221)
                     /locus_tag="RPH49_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125023.1"
                     /translation="MSIMRLFTFILSIFIVGMVEMMVAGIMNLMSQDLHVSEAVVGQL
                     VTMYALTFAICGPILVKLTNRFSSRPVLLWTLLIFIIGNGIIAVAPNFSILVVGRIIS
                     SAAAALIIVKVLAITAMLSAPKNRGKMIGLVYTGFSGANVFGVPIGTVIGDLVGWRYT
                     FLFLIIVSIIVGFLMMIYLPKDQEIQRGSVNHEAPSHENHVTSKILRPAEVAKYLIIT
                     FLVLIANSVTFVFINPLILSNGHDMSFVSLALLVNGIAGVIGTSLGGIFSDKITSKRW
                     LMISVSIFIVMMLLMNLILPGSGLLLAGLFIWNIMQWSTNPAVQSGVIQHVEGDTSQV
                     MSWNMSSLNAGIGVGGIIGGLVMTHVSVQAITYTSAIIGALGLIVVLTLKNNHYAKTF
                     KSS"
     gene            complement(15615..16391)
                     /gene="fetB"
                     /locus_tag="RPH49_001884"
     CDS             complement(15615..16391)
                     /gene="fetB"
                     /locus_tag="RPH49_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDY5125024.1"
                     /translation="MSNTALGLTALLLVIPIIISYKEGLHIIKDLIVATLRAVVQLII
                     LGFLLHYIFKINDKWLLVLCVFVIIVNASWNTISRSSPVMHHVFWISFVAIFVGTALP
                     LAGTIATGAIQFTANEVIPIGGMLANNGLIAINLAYQNLDRAFVQDGTNIESKLSLAA
                     TPKLASKGAIRESIRLAIVPTIDSVKTYGLVSIPGMMTGLIIGGVPPLQAIKFQLLVV
                     FIHTTATIMSALIATYLSYGQFFNARHQLVARNTDVKSES"
     gene            complement(16384..17046)
                     /locus_tag="RPH49_001885"
     CDS             complement(16384..17046)
                     /locus_tag="RPH49_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDY5125025.1"
                     /translation="MLLEIKDLVYEASDRVILNHINLKVDKGETIAIIGPSGSGKSTF
                     QKIICNLISPTSGTLYFKDKPYDDYEPEILRRHISYLMQQSDLFGETIEDNMIFPSLA
                     RNDKFDKKRAKQLIKDVGLGHYQLSSKIEHMSGGERQRIAIARQLMYTPDILLLDEST
                     SALDIHNKEKIENIIFKLADQGVAIMWITHSDDQSMRHFQKRITIVDGQISNIEELNQ
                     HE"
     gene            complement(17392..18468)
                     /locus_tag="RPH49_001886"
     CDS             complement(17392..18468)
                     /locus_tag="RPH49_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDY5125026.1"
                     /translation="MNQSVKLLKHLTDVNGIAGYEMQVKEAMRNYIEPVSDQIIEDNL
                     GGIFGKKNAENGQYSIMISGHMDEVGFMVTKIDKHGFISFTPVGGWWNQVMLSQKVTI
                     TTDSGKEIRGIIGSKPPHVLTPEERKKPMEIKNMFIDIGVSSKGEAEEAGVEVGNMVT
                     PYSEFEVLANNKYLTAKAFDNRYGCALAIEVLQRLKDENIGINLYSGATVQEEVGLRG
                     AKVAANTIKPDLAIAVDVGIAYDTPGMSGQTSDSKLGGGPVVIMMDATSIAHQGLRKH
                     IKDVAKKHNIEVQWDTTPGGGTDAGSIHVANEGIPTMTIGVTLRYMHSNVSVLNVDDY
                     ENSIRLVTEIVRSLNDETYKNIMW"
     gene            complement(18823..19089)
                     /locus_tag="RPH49_001887"
     CDS             complement(18823..19089)
                     /locus_tag="RPH49_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDY5125027.1"
                     /translation="MSNYTVKIKNSAKSDLKKIKHSYLKKSFLEIVETLKNDPYKITQ
                     SFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLILSAWSHYD"
     gene            complement(19089..19346)
                     /locus_tag="RPH49_001888"
     CDS             complement(19089..19346)
                     /locus_tag="RPH49_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDY5125028.1"
                     /translation="MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLE
                     DWKSIQETIYLESTGTMDKVREREKDNSGTTNIDDIDWDNL"
     gene            19705..20160
                     /locus_tag="RPH49_001889"
     CDS             19705..20160
                     /locus_tag="RPH49_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1307 domain-containing protein"
                     /protein_id="HDY5125029.1"
                     /translation="MKKLCSLIVVALVCIIALSACGKEQTKTYEGDVSGKHVLTSITY
                     KDDKVLKQSTINTIKYDDLGMDKDEAKKLFAKSESIFKDLKGVKYKVDYKDKKAIEHL
                     DIDYTEVDMKKLNKRLGVSTKENKDISFEKLEKQLKHRGLKEKDKMDDK"
     gene            complement(20328..21905)
                     /locus_tag="RPH49_001890"
     CDS             complement(20328..21905)
                     /locus_tag="RPH49_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding glutamate synthase family protein"
                     /protein_id="HDY5125030.1"
                     /translation="MTFLTVMQFIVNIIIIGFLLTVIVIGLIWLIKDKRQSQHSVLRN
                     YPLLARIRYISEKMGPELRQYLFSGDNEGKPFSRNDYKNIVLAGKYNSRMTSFGTTKD
                     YQDGFYIQNTMFPMQRNEISVDNTTLLSTFIYKIANERLFSREEYRVPTKIDPYYLSD
                     DHAIKLGEHLKYPFILKRIVGQSGMSYGALGKNAITALSKGLAKAGTWMNTGEGGLSE
                     YHLKGNGDIIFQIGPGLFGVRDKEGNFSEGLFKEVAQLSNVRAFELKLAQGAKTRGGH
                     MEAEKVNEEIAKIRNVEPYKTINSPNRYEFIHNAEDLIRFVDQLQQLGQKPVGFKIVV
                     SKVSEIETLVRTMVELDKYPSFITIDGGEGGTGATFQELQDGVGLPLFTALPIVSGML
                     EKYGIRDKVKLAASGKLVTPDKIAIALGLGADFVNIARGMMISVGCIMSQQCHMNTCP
                     VGVATTDAKKEKALIVGEKQYRVTNYVTSLHEGLFNIAAAVGVSSPTEITADHIVYRK
                     IDGELQTIHDYKLKLIS"
BASE COUNT         7264 a         4276 c         3142 g         7346 t
ORIGIN      
        1 aatatacctc tttaattaat ttattcaata gaactggtat aataaaataa atctcattag
       61 gcacttaagt aaatttaaca tataaaaagg aacgtttatg actactaaaa aactatattt
      121 tctatccatt tctattatca ttttagtcgc catttcaatt gctatatata taacattaaa
      181 tagcaatacg aagacacggt taaccaatga ttcgcaacaa caaatagata caattatcga
      241 gcatgatcta caaaagggac acattcctgg agcatcaatt ttaatagtaa aaaatggcaa
      301 agttttttta aataaaggtt atggttatca agatgttgat aaaaaagtca aagcttctcc
      361 cacaacaaag tatgaaattg cttctaatac gaaagctttc acaggtcttg caattttaaa
      421 attagctcaa gaaggtcgat taaacttaaa tgatgccgta tctaaacatg tgcctcattt
      481 taaaatgaac tataatggtc aaaatgaaac tattacgatt aagcaacttt tggctcaaac
      541 aagtggtata cctagtgata ttacaagcga agactccgta acaaataaaa ataatcgttt
      601 aaatgatgta acccgtgcaa ttatgggtga tgaattacat cataagcccg gagaagaatt
      661 tgaatactca aatatgaact atgatttatt aggtttaatt atccaaaacg ttacgaagca
      721 atcctataca aaatatatta caaattcatg gctcaagcct ttgaatatga cacatacatc
      781 attcaaacaa accaataaca aaacaaaaca tgatgctatt ggctacgaat tacaaggttc
      841 gacacctgtc gtctctaaac ctgaatttaa cctttgggat acaccatcag catatatgat
      901 gacatcaact gaagatttgg aacattggat aaaattccaa cttaatccac ctgataaata
      961 caaatcatta gttcaacaat cacataaaaa tttatcatca acaattggtg aacctaatgc
     1021 caatgcatat gcttccggct ggtttaccaa taatgatgaa catttagtgt ttcattcagg
     1081 aacgctcgat aacttttcat catttatttt actaaatcca aaacaaaatt atggaattgt
     1141 tgtgcttgca aatctaaatt cggaatatgt acccaaatta gttgagcatc ttaacacaca
     1201 aattgtaaat cacaagcgat attcgacagt tgcgtctatg ctcaatcaat ataaaaatca
     1261 atttaatatt gttaccgttt tgatgacaac acttatttta ttagcattta tattctcagc
     1321 ttatcgtgct tggcaaatgc gtcacgggaa aatcatcctg cgcaaatcaa aacttaccac
     1381 attttcaagt tggctaactt tatgtttatg tatcgctata gcgctcatat tatatgcatt
     1441 accatatctc attctcggta gcaataactg gtcttttgta ctgacttggc tgccaataga
     1501 aattaaatta gcactaatca caatattaat tgcattattc agtacattaa ttgtaattct
     1561 gttattcctt catacaaaga taacgaagac ataataaaaa gacttgttcg agccgtgcgt
     1621 ttgataatat atcatccacg attcgaccaa gtctttattc tttgtatatt aaacggataa
     1681 attattattt aattggattc atgccatctt tccaagtttt ataaatcaga gtaccacctt
     1741 gcgctttaaa cttctcattg cttacgccac gttcaaatgg ttgcgcaggt tgtatatcaa
     1801 tatttggttc aacaccaagt tgttctttat accattctgc aaattcagaa cctttaacag
     1861 gtgcatcatc tgctacatta tagataccat tttcaaaatg aatagcttga atagatgttt
     1921 caactgcatc atcaagatgc acaaatgatg ttacgccatc tgaaagtgtc acttcaccat
     1981 ccataaattg attataaatc atgccatctt ttccgtacca agtacctggg ccatataacc
     2041 agccaaaacg taagacaacg tattcatcca tacgagccgt ttcttcttct agaccaacca
     2101 caccatcaac cgttactttt ctatcaccag ttgagttaaa atcaagtgaa gtttcctcat
     2161 ttgctaatcc ttcgccaggt tcatacataa aggcaatact ttgggcaatc actttcttaa
     2221 cgtcatgctt tttcgccgaa tcaattaagt ttttagaacc ttcaatacgt actttcgtat
     2281 ttgctgccat atcaacattt tttaaatccg taatttggtt gataatgatt tctggtttaa
     2341 aatctgctaa cgcttgatca atggtatcag cttttaatat atcaccaata tatgctttta
     2401 cattaacagc agctagcttt tgttgaccat tctcagatgt agtaaaacca gcaacctcat
     2461 gcccctcttc ttttagtctt tgaactaatt taatgccaat aaggcccgtt gcaccagtta
     2521 caaaaatttt actcattata aacacctttt ctctatttgt ctttttaata taattacttg
     2581 cttgatgagt ttacaaaatt cacgtgagac ttccaaatga tttgcctcaa aatttttcaa
     2641 agtgtcgtcg taaaaactgt ctagtaaata ctaatagtat gtcgtagacc tatgacaaat
     2701 ctgaattatg acgaagatca atcaagaaaa acagcaccac gatcatttca atttgaaagt
     2761 accttgctgc tgttctttat ttattacatt tcaatcttag taatgaccgt aattatcacg
     2821 tgattgtcat ttccttgcaa tcatagctaa aaacactaat taatcctgtg cgtgtcgctg
     2881 actttcttta gtatgaatta aatcagtaat aaagcgattg actggcgctt caatatgacg
     2941 ttttttacct aatgttgcaa ctgcgccatt aatataatca atttcagttt ttctattatt
     3001 aacaattaaa tcttgataca tggatggata atgcgcacca actttttcat ttaaatcaac
     3061 taaatattca aagacttcat caacatttaa atgaacatta tcaatcgtcg ctacatgcac
     3121 tatttcttgc gttaatttat aaatcaaaca cttcgcataa ctactttcat tcagtgatgc
     3181 catattacac tccaacactg tgcttaatgc atttgccgta ccattaacac aaatcttttt
     3241 ccaaatcgat tggtataaat ctttactaat gacaccattc aattccgctt cgttaagtaa
     3301 ctcagcaact tttataacat tttctttacc ttcatcaact agttcaccta tttcaactgg
     3361 tccactacca agtaaatgac tgtgtccagg gctttcaaga cctgccgtcc aagtcgtaac
     3421 acctctgaca atttgtgatt gagcaacgta ctgcgcaatg acttcttcat gcttcaaacc
     3481 attcatcgta catacgacaa tcgtttcatt atcaatatgt gatttcatag cttccatcac
     3541 ttcttttaat tgcatagact ttggaaatag aaagacaaca tcgtaaatgc tctcgtccgg
     3601 ttgatcatta aaatgataca tcggaatgtt taactcgaat gcctctccat taatcgttat
     3661 atttaatcca tgttgcttaa ccgcttcaac atgagatgta tatccgtcaa taagtgtgac
     3721 attatatcct gcttgaaata gtttggcacc aaagccactt cctaatgcac ccgatccagc
     3781 aattgcaatt ttcatcctat aaacccctct tcatcgttgt tgttcatttt aaaaatacta
     3841 ctttcgcata ttagcgtcaa tttgaaaatc attcgcttaa tatgcacaca gcttttatcg
     3901 tctataaaag aacacaccta acattaaacg tcaatacgca acattaagtg tgtatgataa
     3961 acttactttc acaaaatttc ctttaaaatc cctacataat aacttgcttt catttcggtt
     4021 ttacaaattc gtttgatttt taggaactaa tagtaaaatg actaaaaatg caacaattgc
     4081 tagcaaggca ttaaacatca tacctgtgaa accacctaag ttcaaattta aattagctgc
     4141 taacacagta taaaccgtac cagatactgc tactccaaat gcatttccta atgatgacgc
     4201 cattttatat acacctgaag caacacccga cttatcatct ggcgcacttg caactgctgt
     4261 atcagttgat ggtgtagcat ataatcctaa accagtacca aacaataaat atccaactat
     4321 actagatacg atataccaca tttctggtaa aaatgttaac gacaataaga ttaacccaat
     4381 cactgtaaag ccacttccta gtaatagtgg gcgcttcgga ccatgttgag ataaaatctt
     4441 ttcacctaca cgaatcattg acaacactgc tattaaatac gttaatgaaa tataacccgt
     4501 ttgcgaagaa ttaaatccta attgttgttg ataatacgtg ttaatgacga taagtgcacc
     4561 acctgctaca ccatttaata agaagtttga aatagttgca ccactgtatc ctctattttt
     4621 aaaaattgaa aaatcaacaa gtggatgctt tattttattt tcgtaatata caaaaccaac
     4681 taatgaacag ataaacacta taattaaacc tagaattaac ggtgaaacta aaccaaaatg
     4741 agacgtctgt gtgatgatta catttaaact taacattgtc actactaaaa tgactaaacc
     4801 gataacgtca aactttttag cttctgcttt catacctttg attggttctg ctttagtctc
     4861 aggtgcatgt ttgattaagt acattgctaa taaagttaat agaattgaaa caacaaatat
     4921 tgaacgccaa cctatatatg tagccattaa gccaccaaac aacgtacaaa taccactacc
     4981 accccaagaa ccaatagacc aatagcttaa ggcacgttgt cgtcttgtac caatataata
     5041 ttcgttaata atagcaagtg tggatggcat aatacatgct gcagacaaac cttgaattat
     5101 tctacctata attaaaaatg ctggcaaagg tgtaataatg atgagtaacg aacctataac
     5161 atttaatatc aatcctacat aagtaatttt gacgcgacca aatttatcag caacatcacc
     5221 agcacctacg ataaacaaac cagcaaataa ggcagataag ctaacagcga tatttatcgt
     5281 tccaacgtca ctactatatg ttgattgtaa tgggacaaca agattaacaa gtgactgcgc
     5341 gaataaccaa aaggtaataa cccctaaaac gatacccaaa agcaatcggt tgtcacctct
     5401 aaattgtttt gatgtgtcca tgaattagat aagcctccta tgtttaagaa aaacaaattt
     5461 ttaatatgat atattaagaa acaatatcat aaatttgcag aaaattataa ataaaacatc
     5521 tcattcttta gtatttttac aataatcaac gctttttatc caaaaacttt catgataata
     5581 attgctattt tagtgtaaac gcatacaaac acaacctata aaacggctac tcaaagacta
     5641 tttgagctcc ttgagtagcc tcatttttta taaatcatga aacgaaatcg ctaaataata
     5701 aacatcttct actattacat attaatactt tgcggccgat gattagattg atttttacga
     5761 tgtcgtgttg ttgggtctaa tcgtttttct aaaaatctta atagtacatc aatgacgatt
     5821 gcaatgatag caatcggaat cgcacctgct aaaataaacg ttgtgccatc cgtcgcattt
     5881 gtaccacgaa tcacaatgtc accaagcgta ggtgctccta taaatgatcc aacggcaaca
     5941 acacctatcg caacaaccaa ggcaatacga atgccaccga taataaccga aacagataac
     6001 ggtaattcaa tcattcgtag cacttgattg cgtgtcattc ccataccttt gccagcatcc
     6061 ttaatattcg catcaacact agctatacca gtataagtgt tttttataat tggaagtaac
     6121 gcatataaaa acactgttaa aactactgtt tctgaaccta agcccatgac taacattaaa
     6181 atagctaaca ttgcaatgac tggaactgtt tgaattatat ttgcaattgt aattacaaat
     6241 ccagaaagtt ttgtgtatct tgcaagcaag attcccaatg gaataccaat taaagctgca
     6301 aacagcacac catagacaga cattaataag tgtttgaaaa ataaatccca tagataacca
     6361 aagttcgtaa cataataatt gaataattgc tgtaataaat taccttccat tacttatgac
     6421 cacctttctg tttatcaaaa tagtggtgtt ttttcaaaaa ttcttctgcg acgacagcag
     6481 gttctttacc tttaccatcc gcttcataat tcaagcgttg catctctgaa gtcgaaatct
     6541 ttcctgtcaa cttattaatc gtcgttttaa gttctgggtg ttggcgtaat aattcatttg
     6601 ttgcaacagc actcgcagca taaggtggga aaaattgttt atcatcttta agtactttca
     6661 aatcatacgc cgcaattcga ccatctgtag aataacctaa tgcaacgtct aacttctctg
     6721 agtttaatgc gtcgtagact agacctattt gcattggtct cactgtacca aagtcgaaac
     6781 catactcttt tttaaatcct tcatagccat cgcctttacg attcatccat gaactatcca
     6841 tacctaaacg taaatcttta ctatgctttg ctaaatctga aactgtctct aaatgatatt
     6901 ttttagcagt ttcctccgtt accatgaatg catacgtatt cgcaaaacca tacgaatcaa
     6961 aaaacgtttg atcaaatttc tttttaaatc cttgttgtgt ggctatcatt gctttcttag
     7021 gatctttaat tggtgcttcc ttcaaagctc ccgttaaatc tgtgccatta tatctaacac
     7081 ctgatatatt agcatcccca ttaattaagg cattatgttg aatcgtactt gaccctaaat
     7141 tatttactaa tgttggcttt atcttaccat gtgtatcatg ctctattaac aaccgtaaca
     7201 tatgtgaaat aatttgcgat tcgcttgttg ataatgctgt aattttgaca tcatttttcg
     7261 tgctcttact acctagtccg ggcaaactac atccagataa tacggtaagc gataagacaa
     7321 acacgacaag tatatattta attttcttca ttatcttagc ctcctaatta tccagatact
     7381 tttaagcctt tgggaactac ccatttttca actaaagcta ataaggcatc aacacctaat
     7441 gctagtgcag taacgagtac cgttgcagtt acaatcatca gtggatcata taaatttaaa
     7501 ccattgaaaa tgaaatcacc taatccaccc gcacctacat aacttgcaag tgtagcccaa
     7561 ctaattacat acacagatga caaacgaatg ccaccaatga taagcggcaa tgctaacggc
     7621 aattcaacat ccttcatcaa ttgaaattgt gtcattccca tactttttcc agcttcttta
     7681 atgttgctat caatattttg aacgccgagt accgtgttat ttaaaatagg taataacaca
     7741 taaataaata gcgctacaat tgcaggcgtt ttaccaacac caaaaatcgg tatcataata
     7801 gcaagtacag ctagtgttgg aatcgtttgt aagacacctg ccacagttaa tataatattg
     7861 gcagttcgct ttgtttttga taataaaatg cctataggta ctgcaacaat gatggcaagt
     7921 aataatgcca ctatagaaat atagaaatgt tccagtgttt tcgacatcaa ctgtccacca
     7981 tgttcatgta ggaactcgat catgatttat catctcctat gtcacgtact ttgacattag
     8041 tagtgtgttg ctcatgcatt tttgaggacg cagtgtcttc ccccacatgt tctgtttgca
     8101 ctgcatcctc actatcgccc caaatcgtgt catatacaat atcaacaaca ttggcacgcg
     8161 taatcagtcc tactaaacgt tgcttatcat ctacgacagg tacattccta acgtttcttt
     8221 ttaaaatcgt acgtacagaa tcttgtaatt tagaatcaat ttgaacggtg taaatatgtt
     8281 gttgcatggt gtctcgtaaa cttttgtgtc cacgtatacc ctgatttata tcttcaatgt
     8341 ctaagaaacc tagtaaatgg ttattactat ctactacaaa aatagtatca acacgttttt
     8401 gtctcataat atgaacggcg tcattcagtg ttgcttctgc ttgtatcgtg attggtttaa
     8461 tcattacacc ttctacagtc ttgtcattgg gacggtcttg aatcagtcta ttttgtccta
     8521 taaaatcacg tacaaaatca tttgcgggat gtcttaaaat attgtctggc gtatcaaatt
     8581 gcaccacctt accttctgac ataatacaaa ttttgtctgc taatttaatc gcttcatcca
     8641 tatcatgtgt tacaaagata aacgtcttgc ctaattttcg ttgtaacgtt ttaactaaat
     8701 cttgtaacgt atctctcgta ataggatcca atgcaccaaa aggttcatcc attaaaataa
     8761 tatcttgttc ggccgcaagt gctcttacga caccgatacg ttgttgttgc ccacctgata
     8821 gttctgctgg ataacgctct aaaaatgact ccggtaaatc cacaagttta attaattcct
     8881 ttgcacgttt atccttttct tctttagtcc atttcaacaa cttgggtacc aacacaatat
     8941 tctctttaat cgtcatatga ggcattaagc caatttgttg aataacatag ccaatatttc
     9001 tacgtaattc gacaggattc atactccgaa cgtctttgcc atcaatttca atttgtcctt
     9061 ctgtcgcttc aatcatacgg tttatcattc ttaaagcagt tgttttacca cttccactgg
     9121 ttccaataaa tgcgataaat tccccagatt gaatatctaa agagatgtca tctactgcct
     9181 ttttattacc agaataaatt tttgttaaat gcttaatact taacataatc atttctcctt
     9241 cctcataaaa aatatgacga atgatacgca taaaataaaa agaccatcat cgcaattgtt
     9301 aaacaaatag agtcataagt taaacaagta cacatcatgg tcttgattat gtagaatttt
     9361 atatttttca tctgtaatgt gaatacttaa cagtaaacgg cgctatgtat gttgaatttc
     9421 taccgattac tttgtttgca cattcgtata ttcgacattt aaaactaaca tactctatat
     9481 gatgttatta aacattatta ttttatcttt ggcaactaaa tagataactc atatttttta
     9541 aaagcgaatt tattatcgct caattggttg ttttatagca aaaaagtgtc gaaaatgtga
     9601 aatattatta caaaagtcga atttttgtaa taatgcacac gcatccattg ttacaggcgg
     9661 acaaaagccc atccgccacc cacaaagtca tccttatatt ttaatatctt catcattcat
     9721 tgtagacacc attacctttt gctaacagtt cctactccca agcctgtaac ggaattccaa
     9781 cgtcaaagtg ttgcccatga cagcacacct aaaaaaacaa ccaacagcat gagccattgg
     9841 ttgtttcgtg tcatcttgta tgttgttgta taaccggtat gcttttactc attaattact
     9901 tatcatgcat ccctttacct tctagtattt ggttaatata cttttcaaca cgcttttgtc
     9961 ttgtttcact gcgtttagct tgcccaatat gatatatata ttgatgttgt ctgcctggcg
    10021 ttaatttata aaatgacgac tctagctgtg gcatttcttc gaacttagct tctaactctt
    10081 taggaataac atattcctct gttttcttca tttcaacttt tttaccagct ttttcagctt
    10141 taattgcttc ggctagataa tatttaattt cttcgctacg tgcttgaatc tctgttaaat
    10201 tttcaaatcg taactgacga gctgcttgca ccttttcagt ctgttgaatg agtgtatgat
    10261 atttatcctc caaaatggca cctttatgaa ataatagtgc aacataattt ttgaagccat
    10321 ggataagtac tacattttta ttattcaacg tgtaacaagg atgcatccat ttatacgctt
    10381 cctctaattc tgtttcatta aagattaacg ctctcaaata tttatattct tcttgccatt
    10441 gactctcttt atttaaaaat gcttcaactt gttcatttga ttgtttctca ctcatagtca
    10501 tcacttccat tttgtttttc aatacacatt gtattatata tcctaatttt ataaaaaact
    10561 aattttacaa atgcttttgc gttcttacaa aaaatgcatt tgactattat tataataagc
    10621 gtataatttt tcgcatatta ttttttgaat tttcggcaat aacgaaggag tatttatgaa
    10681 taaagacaag caattgcaca acgacaaaat caatctatcc caattagtat tactagggtt
    10741 aggttcatta ataggatctg gttggctatt tggtgcgtgg gaagcatcat caatagctgg
    10801 accagcagca atcatatcat gggttcttgg attcctagtc attggaacca ttgcctataa
    10861 ctacattgaa atcggcacaa tgtttcctca atcaggtggc atgagtaact atgcccagta
    10921 tacacatggc tcattattag gctttattgc tgcttgggcg aattgggtgt ctttggtgac
    10981 aataatacct atcgaagctg tgtcagctgt tcaatatatg agttcttggc cgtggcattg
    11041 ggcgaaacca atgagatatt taatggaaaa tggctctatt agcacatacg gattgctagc
    11101 tgtatatctc atcattgtta ttttttcatt attaaactat tggtccgtaa aacttttaac
    11161 atcatttacg agtttaattt ctgtatttaa attaggcgta cccatgttaa ccatcatcat
    11221 gttgatgtta tcaggattcg acacttcaaa ttacggccat tcggcaagca catttatgcc
    11281 ttacggaagt gcaccgattt ttgctgcaac aacagcatca gggattattt tttcattcaa
    11341 ttcattccag acaattatta atatgggttc agaaattaaa aatcctgaaa aaaatatcgc
    11401 aagaggcatc gctatctcac tgtcaatcag tgcagtgttg tacatcattt tacaaagtac
    11461 gtttatcact tctatgcctc aatcaatgtt acaacatagt ggatggaatg gcatcaactt
    11521 caattcacca tttgctgatt tagctatctt attaggaatt aattggctcg caattttact
    11581 atatattgaa gcttttgtat caccattcgg tactggcgtg tcatttgtcg ccgttacagg
    11641 tcgagtttta cgagcaatgg agaaaaatgg acatatccct aaatttcttg ggaagatgaa
    11701 tgaaaaatat catatcccac gtgtagcaat catctttaat gccatcatta gtatgattat
    11761 ggttacatta tttagagatt ggggtacgct agcagcagtt atttctactg caactttagt
    11821 agcctattta actggcccaa cgacagtgat tgcattaaga aaaatgggac caacaatgac
    11881 tcgtccattt agagcaaaaa ttttaaaagt aatggcacca ttatcatttg tattagcttc
    11941 attagctata tattgggcaa tgtggccaac aacggctgaa gttattttaa tcattatact
    12001 tggattacca atctacttct tctatgaata tcgtatgaat tggcgtaata caaagaaaca
    12061 aattggtggt agcttatgga ttattgtata tttaatcgtg ctatcaatac tgtcatttat
    12121 aggaagcaaa gaatttaaag gcttaaatat gattcactat ccatttgact ttatcgttat
    12181 tattattgtg gcgcttatct tctattacat cggtacaacg agttcatttg aaagcgtcta
    12241 tttccgtcgc gcaacacgaa tcaatacgaa gatgcatgag tcactaaata atgaatcaaa
    12301 gtcatctcat taaatatttt aaaatgcagt gccatatatg atttcaacac acacattaac
    12361 caaccattga tttcaacatc ttggttggtt ttttattttg aaaatcggtt ataaataact
    12421 aacataacaa gatggcgaga gtgatattgt aatgaaatgt cactgtagaa gaacatcata
    12481 taatgctgaa aatggtttga gttaaaacag atatcaagct cgtctgattc agtcacaaaa
    12541 ttgtcttgtt atacttgtca cctatcatct atagaccgtg gtatgattaa attggggatg
    12601 ataaaggagg ttaataaata tgaagattaa tactacaggt ggtcaaattt atggtattac
    12661 acaagatcgt ttagatatct tcttaggcat tccttatgca gaaccaccag ttcatgacaa
    12721 tcgctttaaa cattctacgt taaaaacaca atggtcagag ccaattgatg caactgaaat
    12781 acaacccatc ccaccgcaac cagacaacaa attagaagat tttttctcct cacaatctgc
    12841 aacttttacc gaacatgaag actgtttata tctaaatatt tggaaacaac ataatgatca
    12901 gtcgaagaaa cctgtcatca tttattttta tggtggtagt tttgaaaatg gtcatggtac
    12961 agccgaactc tatcaaccgg cacatttagt acaaaataac gacattattg ttattacatg
    13021 caattatcgt ttaggcgcat taggatattt agactggtca tattttaata aagggtttca
    13081 ttccaataat ggactttcag atcaaatcaa tgtcataaaa tgggtgcatc aatttattga
    13141 atccttcggt ggcgacgcta ataacattac tttaatgggt cagtctgcag gcagtatgag
    13201 cattttgact ttacttaaaa tacctgacat tgagccatac ttccataaag tcgttctact
    13261 aagtggcgca ctacgattag acacccttga gagtgcacgc aataaagcac aacatttcca
    13321 aaaaatgatg ctcgattata tagatacaga tgatgttaca tcattatcga cagatgatat
    13381 tcttatgctg atggcgaagc taaaacaatc tcgaggacct tctaaagggc ttgatttaat
    13441 atatgcgcct attaaaacag attatataca aaataattat ccaacaacga aaccaatttt
    13501 tgcatgttat acaaaagatg aaggcgatat ttatattact agtgaacaga aaaaattatc
    13561 accgcaacgc tttattgaca ttatggaatt aaatgatatt cctttaaaat acgaagatgt
    13621 tcagacggcg aagcaacaat ctttagcgat tacacattgt tatttcaaac agccgatgaa
    13681 gcaattttta caacaactta atatacaaga ttcaaacgca caactatggc ttgctgaatt
    13741 tgcatggcat gatacttcta gcgcacacta tcgcagtgcg taccatattc ttgatatgat
    13801 attttggttc ggaaacttac aaattttatc agcgcatcag tatccaatca ctgatcatct
    13861 taaattttta agtcgacaaa tgcaaaatga tttagctaat tttgctaaaa gcggtaaaat
    13921 gccttggccg atatatcata atgaacgtcg ctattatcgc acatatcaat aacgttattg
    13981 catctaaaaa agcacacctg aatttgatag caggcgtgct tttcatatga gaattatgat
    14041 gatttaaatg ttttagcata atgattattt ttcaatgtta aaacaacgat taatcctaat
    14101 gcgccaatga tggcactcgt atacgtgata gcttgaacag aaacatgtgt catgaccaag
    14161 cctccaataa tgcctccaac accaatacca gcgtttaaac tagacatgtt ccaactcatt
    14221 acttggcttg tgtcgccttc aacatgttga atcacaccgc tttgcactgc tggattagta
    14281 ctccattgca tgatattcca aataaatagt cctgctaaca atagacctga accaggtaag
    14341 attaaattca taagtaacat catcacgata aaaattgaaa cagaaatcat taaccaacgc
    14401 ttacttgtaa ttttatcgga gaatatacca cctaatgatg ttccaataac gccagcgatt
    14461 ccatttacta gaagtgctaa tgaaacgaat gacatatcat gaccattaga taaaataagt
    14521 ggatttataa agacgaatgt cactgagttt gcaatcaata ctaaaaacgt aataattaaa
    14581 tattttgcta cttcagcagg tcttaatatt ttcgaagtaa catgattttc atgagatggt
    14641 gcctcatgat tcacagagcc tcgttgtatt tcctgatcct tcggtaaata gatcatcatc
    14701 aagaagccaa caataatact cacaataatt aagaatagaa atgtatagcg ccaacctact
    14761 aaatcgccga taaccgttcc aattggtaca ccaaaaacat tggcaccact aaatcctgta
    14821 tagacaagtc caatcatttt gccacgattt ttaggtgctg ataacatcgc tgtaatagct
    14881 aatactttca caataattag tgctgctgct gcagatgaga taattctacc aactactaat
    14941 attgaaaaat ttggcgctac agcaataatg ccattaccaa tgataaatat aagtaatgtc
    15001 cataataata caggccttga tgaaaaacgg ttcgttaatt taaccagaat aggtccacat
    15061 atcgcaaatg ttaaagcgta cattgtcact aattgaccaa cgacagcttc tgatacatgt
    15121 aagtcctgac tcatcaagtt cataattcct gcaaccatca tttcaaccat tcctacgata
    15181 aaaatactta aaatgaatgt aaatagtcgc atgattgaca ttttaaaact cctttcaaac
    15241 aaaatttccg atattcattt cccttagaat aacgatttat taaaaaatgt gtgcaacaca
    15301 attttatata taaccgttct attatataat attttgcttt aattttctgt gcttaattgg
    15361 aaaattattg aaattgtttt tcagtatttg aaaaattaac acaagtatgt catttaataa
    15421 ttatgtataa ttacttcagt ttcaacaatg actccaaaaa agcacgcacg ctttatatgt
    15481 cagaacagat aactgactac aaagtatgcg tgcctttatg aatattttcg ctgcgctaaa
    15541 taataacatt actatatgtg catcacttta tttccaatta aaactaatgc ctaaatatga
    15601 tgcggtaaaa tctatcatga ctcactctta acatccgtat ttcgtgctac taattgatgt
    15661 cttgcattga aaaattgacc atagcttaaa tatgtcgcaa tcaaagcaga cataatggtc
    15721 gcagttgtat gaataaacac gactaacaat tgaaatttaa tcgcttgtaa aggtggtacg
    15781 ccaccaataa ttaagcctgt catcatacca ggaatcgaca caagcccata tgttttaacc
    15841 gaatcaattg ttggcactat agctaaacga atactttcac gtattgcacc tttagaagcc
    15901 aatttaggtg tagctgcaag tgataattta gattcaatat tagtaccatc ttgtacgaat
    15961 gcacgatcta aattctggta agctaaatta attgcaatca agccattatt tgcaagcatg
    16021 ccgccgatag gtataacttc attggctgta aattggatgg cccctgtcgc aatagtacct
    16081 gcaagcggta atgccgttcc aacaaagata gccacaaagg aaatccaaaa gacatgatgc
    16141 atgacaggtg atgatcgact aatcgtattc caagaagcat taacaataat gacaaataca
    16201 cataatacta atagccattt gtcattaatt ttaaaaatat agtgcagtaa gaatcctaaa
    16261 atgattaatt gtacgaccgc acgtagtgtc gccacaatca aatctttaat aatatgtaga
    16321 ccttctttat aagaaataat aattggaata actaatagca gtgccgtcag tcctaatgcc
    16381 gtattactca tgttggttca actcctctat attagaaatt tgaccatcaa caattgttat
    16441 acgcttttga aagtgtcgca tactttggtc atcgctgtgg gtaatccaca taattgccac
    16501 gccttgatct gctaatttaa aaatgatatt ttctattttt tctttattat gaatatctaa
    16561 cgcacttgtt gattcatcta atagaaggat gtctggggta tacattaatt ggcgtgcaat
    16621 cgcgatcctt tgacgctcgc cacctgacat atgttctatt ttagaactta attgatagtg
    16681 tcctaaacct acatctttaa ttaattgctt agcacgtttc ttatcaaatt tatcattacg
    16741 cgcaagagac ggaaaaatca tattatcttc aatcgtttca ccaaacaaat cgctttgttg
    16801 catcaaatag ctaatgtgtc ggcgtaatat ttctggttcg taatcatcat atggtttatc
    16861 tttaaagtaa agtgttccac tggttgggct aattaaattg catattattt tttgaaatgt
    16921 acttttccca ctacctgaag gaccaataat cgcaatggtt tcacctttat ctacttttaa
    16981 attaatatga tttagtatga ctctatcact tgcctcatat actaaatctt ttatctctaa
    17041 caacatattt acccctcctc gtatcatgag ttatttcgat ataatagggt attccttttc
    17101 ttgaatagtg tgcttaccta taagtcgacc tagtcaatgc ttattacccc ttaaaatcgc
    17161 tctaataaga catatcaaat atagtattcc catttttgaa aaatttagtg ccatttcatt
    17221 ccgggaaatt tttttaacat ttatgtcaaa attgaagtac actgcagtga cttattctca
    17281 ctttttgaaa ataaaaaagc ctttaacatg acatctcatg ctaactaagc atctaactta
    17341 gttcttgcat gacatcatat taaagacttt ctttattatt tatggatttg actaccacat
    17401 gatattttta taagtttcat cattcaatga acggacaatt tcagtaacaa gacggataga
    17461 attttcataa tcatccacat tgagtaccga tacattagag tgcatatatc gtaacgtgac
    17521 acctattgtc atcgttggaa taccttcatt tgcgacatga atacttcccg catctgtacc
    17581 tccacctggt gtcgtatccc attgtacttc gatgttatgt ttcttagcta catctttaat
    17641 atgcttacgc aaaccttggt gcgcaatact tgtagcatcc atcataataa caactggacc
    17701 accgcctagt ttactatcgc tcgtttgacc tgacatacct ggggtatcat aagcaatacc
    17761 tacatcgacg gctatcgcca agtctggttt aatcgtattc gctgccactt tagcaccacg
    17821 caaaccaact tcttcttgca ctgtggcacc actgtataag ttgatgccaa tattttcatc
    17881 ttttaaacgt tgtaatacct caatagctaa tgcacagcca tagcgattat caaatgcttt
    17941 cgcagttaaa tatttattat ttgcaagcac ttcaaattca ctatatggcg taaccatatt
    18001 gcctacttca acgccagctt cttcagcttc tcccttgcta ctaacaccaa tatctataaa
    18061 catatttttg atttccattg gctttttacg ttcttcaggc gttaagacat gtggcggttt
    18121 agaaccgatg atacctctaa tttctttgcc cgaatctgtt gtaatcgtta ctttttgaga
    18181 tagcatgact tgattccacc atccaccaac tggcgtaaat gaaataaaac catgtttatc
    18241 aatctttgtt accataaaac caacttcatc catatgacca gaaatcataa ttgagtattg
    18301 accattctca gcatttttct ttccaaaaat gccacccaag ttatcttcaa taatttgatc
    18361 actgacaggc tctatatagt tacgcattgc ttctttaact tgcatttcat aaccagcaat
    18421 gccgtttaca tctgttaaat gtttaagtaa tttgactgac tgattcatgt tattcatcct
    18481 cctgtatttc aacttaaaac tattgtatca ctaactttca gaaaaacgtt ccctaccgct
    18541 ttatcatttt caggcttaaa tatttttaaa attttgtgag gaatccgctt aaaaacctca
    18601 tatttctaaa atttaatatt ccgaaaaagt cagaatttaa aattccttat tataatacgt
    18661 tattctttta ttgttactaa tttcaatctt tttagtcttg cgctattata aaattaaaaa
    18721 gtgtagagat aacaacgcat taacgtcgct attttcccta cacttaaata ctagtttctt
    18781 taattaactt atcattaaag ttattcagat attgaatatt cattaatcat aatgtgacca
    18841 tgccgatagt attaatactt ctttatttcg atcatctacg gtatagacga ccctgtgctg
    18901 atggttaatt cttcttgaat atcgctctaa atatttaggc tctaattttt caaaagattg
    18961 tgttatttta tacggatcat tttttaaagt ctcaacaatt tctaaaaatg acttctttaa
    19021 ataagaatgt tttattttct ttaaatctga tttcgctgaa tttttaatct taaccgtgta
    19081 attgctcatt aaagattatc ccaatcaata tcatctatat ttgttgtacc actattatct
    19141 ttttctcttt ctcttacttt gtccattgta ccagtagatt caagatatat tgtctcttgt
    19201 atacttttcc aatcttctaa acctataatc acagcattat tttcggcatt attgccacta
    19261 atataaattg gttcgtgatt attattaaca ttttttagta attgataaaa atcttttctc
    19321 gcttctgtag ggctagtgat aatcatataa accctccttt gtcttctgtt actctaatta
    19381 tagcgtacgc acttcagtac gtcaatatta ccaacgagtt catcgtattc ttaataccta
    19441 tatgctatcg tacacaagct tttgttcttt tcttccaaca taccgtctat aatgctcaaa
    19501 aagaaatcag cagtggaaca cactacgttc cctaccgctt tatcattttc agacttaata
    19561 attttaaaaa ctttgtgaga aatccgcttc aaaaacctca tatctccaaa aaaaatgaca
    19621 aaatttaaat ttttgaataa catcattttt tagtaaatgt tataatttct ttataataca
    19681 aatatcgaaa gaaggcgact gactttgaaa aaattatgtt cattaattgt agtagcatta
    19741 gtttgtatca ttgcattatc agcttgtggt aaagaacaaa ccaaaacata tgaaggtgat
    19801 gttagtggta aacatgtact aacttctatc acatataaag atgataaagt tttaaaacag
    19861 tctacaatca acacaattaa atatgacgat ctaggtatgg ataaagacga agccaaaaag
    19921 ttattcgcca aatctgaaag tattttcaaa gaccttaaag gcgtaaaata caaagtagac
    19981 tataaagata aaaaagcaat tgaacactta gacatagatt acacagaagt tgacatgaaa
    20041 aagttaaata aacgtcttgg tgtttcaact aaagaaaata aagatattag ttttgaaaaa
    20101 cttgaaaagc aattaaagca cagaggttta aaagaaaaag ataaaatgga cgataaatag
    20161 tttataactt aaaaatgccc tcagataaga ctaaggttac aaaccttaat tcatattctg
    20221 agggctttaa tatttgaaat tcttctgtga ccagcatcca ctactaatat aaaattattt
    20281 gcagtaacgc taaaatccgc tgctttcatt ttcccgaaat aaataagtta actaatgagt
    20341 tttaatttat aatcatgtat cgtttgcaat tcaccatcga tttttcgata tacaatatga
    20401 tcagcagtaa tttctgtagg actggatacg ccaacagctg ctgcaatatt gaataagcct
    20461 tcatgcaaac ttgttacata gtttgtgaca cgatattgct tttctccaac aatcaatgct
    20521 ttttcttttt tcgcatctgt cgttgcaaca cctacaggac atgtattcat atgacattgt
    20581 tgactcataa tacaaccgac actaatcatc ataccacgtg caatattaac aaaatctgca
    20641 cctaaaccta gtgcaatcgc aattttatca ggtgtcacta acttaccaga tgccgccaat
    20701 tttactttat cacgaatacc atatttttct aacatgccag acacaatagg tagagctgta
    20761 aatagcggta agccaacacc atcttgtaat tcttggaatg ttgcaccagt accaccttca
    20821 ccaccatcaa tcgtaataaa gcttggatac ttatctaatt ccaccatcgt acgtacaagt
    20881 gtttcaattt ctgaaacttt gcttactaca attttgaatc ctactggttt ttgacctaat
    20941 tgctgcaact gatcgacgaa acgaatcaaa tcttcagcat tatgaataaa ttcgtaacgg
    21001 ttaggtgaat tgattgtttt ataaggttca acatttcgga ttttagcaat ttcttcgttt
    21061 accttttcag cttccatatg accaccacga gtcttagcac cttgtgccaa cttcagctca
    21121 aatgcgcgta cgttagataa ctgtgcaacc tctttaaata aaccttcact aaaattacct
    21181 tctttatcac gaacaccaaa taaaccggga ccaatttgga aaatgatatc cccattacct
    21241 tttaaatgat attctgataa gccaccttca cctgtattca tccaagttcc cgctttagct
    21301 agacctttag ataaagctgt aatggcattt tttcctaagg ctccataact cataccagat
    21361 tgtcctacga tacgttttaa aataaatgga tattttaaat gttcacctaa ttttattgca
    21421 tgatcatcac ttaagtaata cggatcaatc tttgtcggta cacgatattc ttcacgacta
    21481 aataaacgct cattcgcgat tttataaatg aatgttgata acaatgttgt attatctact
    21541 gaaatctcat tacgttgcat cggaaacatt gtgttctgta tgtaaaagcc gtcttgataa
    21601 tctttagtag taccgaagct ggtcatacga gagttatatt ttccagccaa aacgatattt
    21661 ttataatcat tacgtgaaaa aggtttccct tcattatccc cagaaaataa atactgacgt
    21721 aattccggcc ccattttttc tgaaatatat ctaatacgtg ctagtaaagg ataattcctt
    21781 aatacactat gttgtgattg tcttttatct ttaattaacc aaataagccc gataacaata
    21841 accgtaagca ggaagcctat aatgataata ttaactataa attgcatgac tgtaagaaac
    21901 gtcattacaa tacctccccc caaaatttca attcaatatt tatgatacac cttacaaaat
    21961 aaaacacaat ggaagcgctt cattttataa aacaatttta tgatatgttt ttcattttaa
    22021 attttaat
//
LOCUS       DAPSKH010000047        21988 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPSKH010000047 DAPSKH010000000
VERSION     DAPSKH010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21988
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.047"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            122..496
                     /locus_tag="RPH49_001891"
     CDS             122..496
                     /locus_tag="RPH49_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125031.1"
                     /translation="MDDIQKIKKELSELVERVDDVEILANETADHVLELREEHKQHHN
                     ELRESHKELKDKQDKVVDENLEQTKILNRIEERYQTQVDVAQKNEEKTLAQNKWLVGA
                     IWALVTIVMIAVITASITALLP"
     gene            622..924
                     /locus_tag="RPH49_001892"
     CDS             622..924
                     /locus_tag="RPH49_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDY5125032.1"
                     /translation="MDAKVITRYIVLILALVNQFLANKGISPIPVDDETISSIILTVV
                     ALYTTYKDNPTSQEGKWANQKLKKYKAENKYRKATGQAPIKEVMTPTNMNDTNDLG"
     gene            935..2389
                     /locus_tag="RPH49_001893"
     CDS             935..2389
                     /locus_tag="RPH49_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDY5125033.1"
                     /translation="MLITKNQAEKWFDNSLGKQFNPDLFYGFQCYDYANMFFMIATGE
                     RLQGLYAYNIPFDNKARIEKYGQIIKNYDSFLPQKLDIVVFPSKYGGGAGHVEIVESA
                     NLNTFTSFGQNWNGKGWTNGVAQPGWGPETVTRHVHYYDDPMYFIRLNFPDKVSVGDK
                     AKSVIKQATAKKQAVIKPKKIMLVAGHGYNDPGAVGNGTNERDFIRKYITPNIAKYLR
                     HAGHEVALYGGSSQSQDMYQDTAYGVNVGNNKDYGLYWVKSQGYDIVLEIHLDAAGES
                     ASGGHVIISSQFNADTIDKSIQDVIKNNLGQIRGVTPRNDLLNVNVSAEININYRLSE
                     LGFITNKKDMDWIKKNYDLYSKLIAGAIHGKPIGGLVAGNVKTSAKNQKNPPVPAGYT
                     LDKNNVPYKKEAGNYTVANVKGNNVRDGYSTNSRITGVLPNNATIKYDGAYCINGYRW
                     ITYIANSGQRRYIATGEVDKAGNRISSFGKFSAV"
     gene            2779..3717
                     /gene="lukS-PV"
                     /locus_tag="RPH49_001894"
     CDS             2779..3717
                     /gene="lukS-PV"
                     /locus_tag="RPH49_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Panton-Valentine bi-component leukocidin subunit
                     S"
                     /protein_id="HDY5125034.1"
                     /translation="MVKKRLLAATLSLGIITPIATSFHESKADNNIENIGDGAEVVKR
                     TEDTSSDKWGVTQNIQFDFVKDKKYNKDALILKMQGFINSKTTYYNYKNTDHIKAMRW
                     PFQYNIGLKTNDPNVDLINYLPKNKIDSVNVSQTLGYNIGGNFNSGPSTGGNGSFNYS
                     KTISYNQQNYISEVEHQNSKSVQWGIKANSFITSLGKMSGHDPNLFVGYKPYSQNPRD
                     YFVPDNELPPLVHSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHATRRTTHYGN
                     SYLEGSRIHNAFVNRNYTVKYEVNWKTHEIKVKGHN"
     gene            3713..4696
                     /gene="lukF-PV"
                     /locus_tag="RPH49_001895"
     CDS             3713..4696
                     /gene="lukF-PV"
                     /locus_tag="RPH49_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Panton-Valentine bi-component leukocidin subunit
                     F"
                     /protein_id="HDY5125035.1"
                     /translation="MDMKKIVKSSVVTSIALLLLSNTVDAAQHITPVSEKKVDDKITL
                     YKTTATSDSDKLKISQILTFNFIKDKSYDKDTLILKAAGNIYSGYTKPNPKDTISSQF
                     YWGSKYNISINSDSNDSVNVVDYAPKNQNEEFQVQQTVGYSYGGDINISNGLSGGGNG
                     SKSFSETINYKQESYRTSLDKRTNFKKIGWDVEAHKIMNNGWGPYGRDSYHSTYGNEM
                     FLGSRQSNLNAGQNFLEYHKMPVLSRGNFNPEFIGVLSRKQNAAKKSKITVTYQREMD
                     RYTNFWNQLHWIGNNYKDENRATHTSIYEVDWENHTVKLIDTQSKEKNPMS"
     gene            4945..5130
                     /locus_tag="RPH49_001896"
     CDS             4945..5130
                     /locus_tag="RPH49_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000126131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125036.1"
                     /translation="MFILNTQAHARLDQMAQQFEVVCNGLNENEGQAIQTMDQSASLI
                     RSNLIQVKEQLEKLAVY"
     gene            5221..6156
                     /locus_tag="RPH49_001897"
     CDS             5221..6156
                     /locus_tag="RPH49_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDY5125037.1"
                     /translation="MFKRTKLILIATILLSGCSAMESESKKDTNTETKSVPEEMEASK
                     YVGQGFQPPAEKDAIEFAKKHRKEFEKVGEQFFKDNFGLKVKATNVVGKDDGVEVYVH
                     CEDHGIVFNASLPLYKDAIHQKGSMRSNDNGDDMSMMVGTVLSGFEYRAQKEKYDNLY
                     KFFKENEKKYQYTGFTKEAINKTQNVGYQNEYFYITYLSRNLKEYRKYYEPLIHKNDK
                     EFKEGMQKARKELNYTANTNTVATLFSTNDERNRKEKINNVIDLSEKIERTKDMPIKN
                     TITTQLGNKLIGTKKARFDDKKVVSFGAFEDEYNK"
     gene            6140..6286
                     /locus_tag="RPH49_001898"
     CDS             6140..6286
                     /locus_tag="RPH49_001898"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125038.1"
                     /translation="MNIINDRDLTELSSYMVYQDINKDNNFTVNEKRFKQADEFEDLY
                     REKL"
     gene            6361..7269
                     /locus_tag="RPH49_001899"
     CDS             6361..7269
                     /locus_tag="RPH49_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002955256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDY5125039.1"
                     /translation="MLKKAKLILIATLLLSGCSAMESESKKDTKAETKSVPEEMEASK
                     YVGQGFQPPAEKDAIEFAKKHRKEFEKVGEQFFMDNFGLKVKATNVVGKDDGVEVYVH
                     CDDHGIVFNASLPLYKDAIHQKGSMRSNDNGNDMSMVVGTVLSGFEYRAQKEKYDNLY
                     KFFKENEKKYQYTGFTNEAINKTQNVGYQNEYFYITYLSRNLKEYRKYYEPLIRKNDK
                     EFKEGMQRARKELNYTANTDVVSTLFSTKKNFTKDNTVDDVIELSNKLKDKPNMPQKS
                     QVTIQLGKSSINTKKPFYDDINPIEG"
     gene            7724..8668
                     /locus_tag="RPH49_001900"
     CDS             7724..8668
                     /locus_tag="RPH49_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDY5125040.1"
                     /translation="MLKKAKLILIATLLLSGCSMMKNESSKDTNTETKSVPEEMDASK
                     YVGQGFQPSAEKDAIEFSKKHKDKIAKRGEQFFMDNFGLKVKATNVIGSGDGVEVFVH
                     CDDHDIVFNASIPFDKSIIDSDSSLRSKDKGDDMSTLVGTVLSGFEYRAHKEELDNLT
                     EVLKEYKSKYKYTGYTENAIMKTQNSGFRNEYYYLTAIPYTLDEYKKYFQPLIKEDDK
                     SFRDGMKNSKKQLKDKSRPYIVTTLFSTKDNFTKDNTIDEMIDFSEVLKKKKNIPRDL
                     NVSLQISNKYINTKRPNYSKKDVIEIGVFNHEKANTND"
     regulatory      8874..9008
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            9070..9615
                     /locus_tag="RPH49_001901"
     CDS             9070..9615
                     /locus_tag="RPH49_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDY5125041.1"
                     /translation="MQQNKRLITISMLSAIAFVLTFIKFPIPFLPPYLTLDFSDVPSL
                     LATFTFGPVAGIVVALVKNLLNYLFSMGDPVGPFANFLAGASFLLTAYAIYKNKRSTK
                     SLITGLIIATIVMTIVLSILNYFVLLPLYGMIFNLADIANNLKVIIVSGIIPFNIIKG
                     IVISIVFILLYRRLANFLKRI"
     gene            complement(9721..9969)
                     /locus_tag="RPH49_001902"
     CDS             complement(9721..9969)
                     /locus_tag="RPH49_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002449743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDY5125042.1"
                     /translation="MAKYTIVDMDTCIACGACGAAAPDIYDYDDEGIAFVILDDNQGT
                     AEVPEELYEDMEDAIDGCPTDSIKIADESFDGDALKFE"
     gene            10077..11030
                     /locus_tag="RPH49_001903"
     CDS             10077..11030
                     /locus_tag="RPH49_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5125043.1"
                     /translation="MQHIIKTALQQTFNYKTNKSIYNILVGKKSHQTFFDACSQQQLS
                     LYHSLPLLKYPSFELFLENITEFNAEMEIMLHPRYTFESMGQTFQAIQLLVQTMSNTM
                     QQDFRFVPISQNNKIQETVKIVYNYIKENQLQIDFENELHNLFKAITLKGPCYLHYYL
                     QGYDEPMYTRQQVSLIEKLSQQQLFEYEMNNLVTMMFELESGEYTILSKIIMKPTLLN
                     QTYITYTRLLEQFTMEDIAAQQQVKINTIEDHVLEILIKGYMSNYDDYVEQEDQLQFL
                     NFYQQHRGERLKFYKEQFDTLSYFQLKVLIVGFERGDLNVA"
     gene            11020..12399
                     /locus_tag="RPH49_001904"
     CDS             11020..12399
                     /locus_tag="RPH49_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDY5125044.1"
                     /translation="MLHDILRNKFGFENFKPGQQEIIESIMSQQHTLGILPTGSGKSL
                     CYQIPTYLSGKPTLIISPLISLMDDQVMQLKINGEKRVTCIHSGMDEIEKKHNIKCLR
                     HSRFIFLSPEFLLQPSNFKLISMIDFGMIVLDEAHCLSEWGYDFRPHYALIGKVTKHF
                     KEAVVLALTATAPPHLQDDLTEMLAIQFKVIKTTMNRPNISFKHLNFHDDEDKIEWLL
                     PFLQQSGPTIIYVSSKKMCLNLAHLIYDSGFLTGIYHGDMNYQERHTVQQQFLNNDIP
                     IIVATSAFGMGINKKDIRTIIHFHLSTSPSNYIQEIGRAGRDGELSQAISLFQPDDKY
                     ILETLLFADMITEEDVQNFEIGEFLAPDKQDVLTTLHSFYSIGALKQIFKQSFKRKQL
                     GFFRMIGYCKLDQCRRKYLLEFFGEYPPAQDRCCDNDSNITDIVILNKKKVIRSIGFD
                     EKLQNLFLR"
     gene            12552..13832
                     /locus_tag="RPH49_001905"
     CDS             12552..13832
                     /locus_tag="RPH49_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDY5125045.1"
                     /translation="MSNNFKDDFEKNRQSIDTNSHQDHTEDVEKDQSELEHQDTIENT
                     EQQFPPRNAQRRKRRRDLATNHNKQVHNESQTSEDNVQNEAGTIDDRQVESSHSTESQ
                     EPSHQDSTPQHEEEYYNKNAFAMDKSHPEPIEDNDKHDTIKNAENNTEHSTVSDKSEV
                     EQSQQPKPYFTTGANQSETSKNEHDNDSVKQDQDEPKEHHNSKKAAAIGAGTAGLAGG
                     AASKSASAASKPHASNNASQNHDEHDHHDRDKERKKGGMAKVLLPLIAAVLIIGALAI
                     FGGMALNNHNNGTKENKIANTNKNNADESKDKDTSKDASKDKSKSTDSDKSKDDQDKA
                     TKDETDNDQNNANQANNQAQNNQNQQQANQNQQQQQQRQGGGQRHTVNGQENLYRIAI
                     QYYGSGSPENVEKIRRANGLSGNNIRNGQQIVIP"
     gene            13958..14074
                     /locus_tag="RPH49_001906"
     CDS             13958..14074
                     /locus_tag="RPH49_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125046.1"
                     /translation="MLFNKVLSRILTYKLNFSNSHQKDKTLQSTNLTRKNKK"
     gene            14235..15221
                     /locus_tag="RPH49_001907"
     CDS             14235..15221
                     /locus_tag="RPH49_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpdA family putative bacillithiol disulfide
                     reductase"
                     /protein_id="HDY5125047.1"
                     /translation="MQKVESIIIGGGPCGLSAAIEQKRKGIDTLIIEKGNVVESIYNY
                     PTHQTFFSSSDKLSIGDVPFIVEESKPRRNQALVYYREVVKHHQLKVNAFEEVLTVKK
                     MNNKFTITTTKDVYECRFLTIATGYYGQHNTLEVEGADLPKVFHYFKEAHPYFDQDVV
                     IIGGKNSAIDAALELEKAGANVTVLYRGGDYSPSIKPWILPNFTALVNHEKIDMEFNA
                     NVTQITEDTVTYEVNGESKTIHNDYVFAMIGYHPDYEFLKSVGIQINTNEFGTAPMYN
                     KETYETNIENCYIAGVIAAGNDANTIFIENGKFHGGIIAQSMLAKKQTPLES"
     gene            complement(15336..16304)
                     /locus_tag="RPH49_001908"
     CDS             complement(15336..16304)
                     /locus_tag="RPH49_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDY5125048.1"
                     /translation="MKHLLVIHTGGTISMSQDQSNKVVTNDINPISMHQDVINQYAQI
                     DELNPFNVPSPHMTIQHVKQLKDIILEAVSNKYYDGFVITHGTDTLEETAFLLDLILG
                     IEQPVVITGAMRSSNEIGSDGLYNYISAIRVASDEKARHKGVMVVFNDEIHTARNVTK
                     THTSNTNTFQSPNHGPLGVLTKDRVQFHHMPYRQQALENVNEKLNVPLVKAYMGMPGD
                     IFSFYSREGIDGMVIEALGQGNIPPSALEGIQQLVSLNIPIVLVSRSFNGIVSPTYAY
                     DGGGYQLAQQGFIFSNGLNGPKARLKLLVALSNNLDKAEIKSYFEL"
     gene            16381..17040
                     /locus_tag="RPH49_001909"
     CDS             16381..17040
                     /locus_tag="RPH49_001909"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDY5125049.1"
                     /translation="MKAINIALDGPAAAGKSTIAKRVASELSMIYVDTGAMYRALTYK
                     YLKLNKTEDFAKLVDQTTLDLTYKADKGQCVILDNEDVTDFLRNNDVTQHVSYVASKE
                     PVRSFAVKKQKELAAEKGIVMDGRDIGTVVLPDADLKVYMIASVEERAERRYKDNQLR
                     GIESNFEDLKRDIEARDQYDMNREISPLRKADDAVTLDTTGKSIEEVTDEILAMVSKI
                     K"
     gene            17071..17187
                     /locus_tag="RPH49_001910"
     CDS             17071..17187
                     /locus_tag="RPH49_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125050.1"
                     /translation="MQRLTHIQNECAENDLLKLKGDFYSMMNESCLFIFGKS"
     gene            17304..17495
                     /locus_tag="RPH49_001911"
     CDS             17304..17495
                     /locus_tag="RPH49_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125051.1"
                     /translation="MSVTNLNIAKEADLVTKNVLCNNSRKMHYIQSSYYSNVKVAYLR
                     GFLFYKSIKFYYNISCREQ"
     gene            17752..18927
                     /gene="rpsA"
                     /locus_tag="RPH49_001912"
     CDS             17752..18927
                     /gene="rpsA"
                     /locus_tag="RPH49_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDY5125052.1"
                     /translation="MTEEFNESMINDIKEGDKVTGEVQQVEDKQVVVHINGGKFNGII
                     PISQLSTHHIDSPSEVVKEGDEVEAYVTKVEFDEENETGAYILSRRQLETEKSYSYLQ
                     EKLDNNEIIEAKVTEVVKGGLVVDVGQRGFVPASLISTDFIEDFSVFDGQTIHIKVEE
                     LDPENNRVILSRKAVEQEENDAKKDQLLQSLNEGDVIDGKVARLTQFGAFIDIGGVDG
                     LVHVSELSHEHVQTPEEVVSIGQDVKVKIKSIDRDTERISLSIKDTLPTPFENIKGQF
                     HENDVIEGVVVRLANFGAFVEIAPGVQGLVHISEIAHKHIGTPGEVLEPGQQVNVKIL
                     GIDEENERVSLSIKATLPNEDVVESDPSTTKAYLENEEEDNPTIGDMIGDKLKNLKL"
     gene            19149..20459
                     /gene="der"
                     /locus_tag="RPH49_001913"
     CDS             19149..20459
                     /gene="der"
                     /locus_tag="RPH49_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019167598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDY5125053.1"
                     /translation="MTKPIVAIVGRPNVGKSTIFNRIVGERVSIVEDTPGVTRDRIYS
                     SGEWLTHDFNIIDTGGIEIGDAPFQTQIRAQAEIAIDEADVIIFMVNVREGLTQSDEM
                     VAQILYKSKKPVVLAVNKVDNMEMRTDVYDFYSLGFGEPYPISGSHGLGLGDLLDAVV
                     SHFGEEEEDPYDEDTIRLSIIGRPNVGKSSLVNAILGEDRVIVSNVAGTTRDAIDTEY
                     SYDGQDYVLIDTAGMRKKGKVYESTEKYSVLRALKAIERSNVVLVVIDAEQGIIEQDK
                     RVAGYAHEQGKAVVIVVNKWDTVEKDSKTMKKFEDEVRKEFQFLDYAQIAFVSAKERT
                     RLRTLFPYINEASENHKKRVQSSTLNEVVTDAISMNPTPTDKGRRLNVFYATQVAIEP
                     PTFVVFVNDVELMHFSYKRYLENQIRAAFGFEGTPIHIIARKRN"
     gene            20476..21474
                     /locus_tag="RPH49_001914"
     CDS             20476..21474
                     /locus_tag="RPH49_001914"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDY5125054.1"
                     /translation="MTKITVFGMGSFGTALANVLAENGHDVLMWGKNQDAVDELNTCH
                     TNKKYLKYAKLDVNIIATSDMTKAIQFADIYLMALPTKAMREVATQINDKLTSKKTFI
                     HVAKGIENGTFKRVSEMIEDSISPEYNAGIGVLSGPSHAEEVVVKQPTTVAASSKDKS
                     VSKLTQDLFMNDYLRVYTNDDLIGVELGGALKNIIAVASGIVAGIGYGDNAKAALMTR
                     GLAEISRLGEKLGADPMTFLGLGGIGDLIVTCTSTHSRNFTLGYKLGQGESMDQALSE
                     MNMVVEGIYTTKSVYHLAKEKNVDMPITNALYRVLFENISVKECVKDLMERDKKSE"
     gene            21645..21917
                     /locus_tag="RPH49_001915"
     CDS             21645..21917
                     /locus_tag="RPH49_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDY5125055.1"
                     /translation="MNKTDLINAVAEQADLTKKEAGSAVDAVFESIQNSLAKGEKVQL
                     IGFGNFEVRERAARKGRNPQTGKEIDIPASKVPAFKAGKALKDAVK"
BASE COUNT         8390 a         3080 c         3945 g         6573 t
ORIGIN      
        1 gtgaaagaag ttgtggatag aactgacttg tcatctgata aaacagttga tagcgaaaca
       61 atgtaactat actaagttat gagcattacg ctcatagctt tcttagaaag taggtgtagt
      121 tttggatgat attcagaaaa taaaaaaaga gctttctgaa ttagttgaac gtgttgatga
      181 tgttgaaata ctagcaaacg aaacagctga tcatgtgctt gaacttagag aggaacataa
      241 gcaacatcat aatgaactaa gagaatctca taaagaactt aaagataagc aagataaagt
      301 tgtagatgag aatttagagc aaacaaagat attaaacaga attgaagaaa gatatcaaac
      361 gcaagtagat gttgcacaaa aaaatgaaga aaagacactc gcccaaaata aatggctcgt
      421 aggtgccata tgggcgcttg taacaattgt tatgattgca gtcattactg catcaattac
      481 tgcgttatta ccttaaggga ggtggacaaa atgagttggg caagatggtt gtcatgctat
      541 ttgtatggtc gtaaatgtaa ataatgtttt tggtcagtgc ttcggcactg gctttttatt
      601 ttggataaaa ggagcaaaca aatggatgca aaagtaataa caagatacat cgtattgatc
      661 ttagcattag taaatcaatt cttagcgaac aaaggtatta gcccgattcc agtagacgat
      721 gagactatat catcaataat acttactgtt gttgctttat atactacgta taaagacaat
      781 ccaacatctc aagaaggtaa atgggcaaat caaaagctaa agaaatataa agctgaaaac
      841 aagtatagaa aagcaacagg gcaagcgcca attaaagaag taatgacacc tacgaatatg
      901 aacgacacaa atgatttagg gtaggtgttg accaatgttg ataacaaaaa accaagcaga
      961 aaaatggttt gataattcat tagggaagca gttcaatcct gatttgtttt atggatttca
     1021 gtgttacgat tacgcaaata tgttttttat gatagcaaca ggcgaaaggt tacaaggttt
     1081 atacgcttat aatattccat ttgataataa agcaaggatt gaaaaatacg ggcaaataat
     1141 taaaaactat gatagctttt taccgcaaaa gttggacatt gtcgttttcc cgtcaaagta
     1201 tggtggcgga gctggacatg ttgaaattgt tgagagcgct aatctaaaca ctttcacatc
     1261 gtttggccaa aattggaatg gtaaaggttg gacaaatggc gttgcgcaac ctggttgggg
     1321 tcccgaaacc gttacaagac atgttcatta ttacgatgac ccaatgtatt ttattagatt
     1381 aaatttccca gataaagtaa gtgttggaga taaagctaaa agcgttatta agcaagcaac
     1441 tgccaaaaag caagcagtaa ttaaacctaa aaaaattatg cttgtagccg gtcatggtta
     1501 taacgatcct ggagcagtcg gaaacggaac aaatgaacgt gattttatcc gtaaatatat
     1561 aacaccaaat atcgctaagt atttaagaca tgcaggtcac gaagttgcat tatatggtgg
     1621 ctcaagtcaa tcacaagata tgtatcaaga tactgcttac ggtgttaatg taggaaataa
     1681 taaagattat ggcttatatt gggttaaatc acaggggtat gacattgttc tagagattca
     1741 tttagacgca gcaggagaaa gtgcaagtgg tgggcatgtt attatttcaa gtcaattcaa
     1801 tgcagatact attgataaaa gtatacaaga tgttattaaa aataacttag gacaaataag
     1861 aggtgtaaca cctcgtaatg atttactgaa cgttaatgta tcagcagaaa taaatatcaa
     1921 ttatcgttta tctgaattag gttttattac taataaaaaa gatatggatt ggattaagaa
     1981 gaattatgac ttgtattcta aattaatagc tggtgcgatt catggtaagc ctataggtgg
     2041 tttggtagct ggtaatgtta aaacatcagc taaaaaccaa aaaaatccac cagtgccagc
     2101 aggttataca cttgataaga ataatgtgcc ttataaaaaa gaggctggta attacacagt
     2161 tgccaatgtt aaaggtaata acgtaaggga cggctattca actaattcaa gaattactgg
     2221 tgtattacct aataacgcaa caatcaaata tgacggcgca tattgtatca atggctatag
     2281 atggattact tatatcgcta atagtggaca acgtcgttat atcgcgacag gagaggtaga
     2341 taaagcaggt aataggataa gtagttttgg taagtttagc gcagtttgat aattgtatat
     2401 gatgaatctt aggcaggtac ttcggtattt gcctattatt taaaattaat aaacagttaa
     2461 tttttacata aatatattaa attttaaaaa aacaaacgtt tttagtatat aaattatttt
     2521 gtgttcgtat tgtgtgttat gattaaaaag ttgttatggt caactatatc gtggttttat
     2581 gtttattatc aatcaaaata taaattattt ataatttgtt tggtaatgaa cgggtttttt
     2641 tcgaaataat agtaaaaaaa cacatttata gatattttaa actcggtaaa tcttttaata
     2701 aatatttaat tttattaaaa gttaaaaagg tttaatataa aaatgtaata aaatttataa
     2761 agaaaggaaa tgatttttat ggtcaaaaaa agactattag ctgcaacatt gtcgttagga
     2821 ataatcactc ctattgctac ttcgtttcat gaatctaaag ctgataacaa tattgagaat
     2881 attggtgatg gcgctgaggt agtcaaaaga acagaagata caagtagcga taagtggggg
     2941 gtcacacaaa atattcagtt tgattttgtt aaagataaaa agtataacaa agacgctttg
     3001 attttaaaaa tgcaaggttt tatcaattca aagactactt attacaatta caaaaacaca
     3061 gatcatataa aagcaatgag gtggcctttc caatacaata ttggtctcaa aacaaatgac
     3121 cccaatgtag atttaataaa ttatctacct aaaaataaaa tagattcagt aaatgttagt
     3181 caaacattag gttataacat aggtggtaat tttaatagtg gtccatcaac aggaggtaat
     3241 ggttcattta attattcaaa aacaattagt tataatcaac aaaactatat cagtgaagta
     3301 gaacatcaaa attcaaaaag tgttcaatgg ggaataaaag ctaattcatt tatcacatca
     3361 ttaggtaaaa tgtctggaca tgatccaaat ttatttgttg gatataaacc atatagtcaa
     3421 aatccgagag actattttgt gccagacaat gaattacccc cattagtaca cagtggtttc
     3481 aatccttcat ttattgcaac tgtttctcat gaaaaaggct caggagatac aagtgaattt
     3541 gaaataacgt atggcagaaa tatggatgtt actcatgcta ctagaagaac aacacactat
     3601 ggcaatagtt atttagaagg atctagaata cacaacgcat ttgtaaacag aaattacaca
     3661 gttaaatatg aagtgaactg gaaaactcat gaaattaaag tgaaaggaca taattgatat
     3721 gaaaaaaata gtcaaatcat cagttgttac atcaattgca ttgcttttgc tatccaatac
     3781 agttgatgca gctcaacata tcacacctgt aagtgagaaa aaggttgatg ataaaattac
     3841 tttgtacaaa acaactgcaa catcagattc cgataagtta aaaatttctc agattttaac
     3901 ttttaatttt attaaagata aaagttatga taaagataca ttaatactca aagctgctgg
     3961 aaacatttat tctggctata caaagccaaa tccaaaagac actattagtt ctcaatttta
     4021 ttggggttct aagtacaaca tttcaattaa ttcagattct aatgactcag taaacgttgt
     4081 agattatgca cctaaaaatc aaaatgaaga atttcaagta caacaaacgg taggttattc
     4141 ttatggtgga gatattaata tctctaacgg cttgtcaggt ggaggtaatg gttcaaaatc
     4201 tttttcagag acaattaact ataaacaaga aagctataga actagcttag ataaaagaac
     4261 taatttcaaa aaaattggtt gggatgttga agcacataaa attatgaata atggttgggg
     4321 accatatggc agagatagtt atcattcaac ttatggtaat gaaatgtttt taggctcaag
     4381 acaaagcaac ttaaatgctg gacaaaactt cttggaatat cacaaaatgc cagtgttatc
     4441 cagaggtaac ttcaatccag aatttattgg tgtcctatct cgaaaacaaa acgctgcaaa
     4501 aaaatcaaaa attactgtta cttatcaaag agaaatggat agatatacaa acttttggaa
     4561 tcaacttcac tggataggta ataattataa agatgaaaat agagcaactc atacatcaat
     4621 ttatgaagtt gattgggaaa atcatacagt taaattaata gatactcaat ctaaggaaaa
     4681 aaatcctatg agctaaacag atagataatc aaaaaatctt aaatatgtta aaatttacaa
     4741 acactttctt tctatattag ggtaaccacg tcttaattga cgtggttatt ttttcagggc
     4801 aaaaaaaggg cggattattt aaataagggc aaacacttgt ggaaaattta aaaggttaaa
     4861 aataataaag aacttggtat aacaagggtt ttatacattt gcgtacaacg acgaaatgtc
     4921 aatttaccat ctcattatga cgatatgttt attttaaaca cacaagctca tgctcgtctt
     4981 gatcaaatgg cacaacagtt tgaagttgtt tgtaatggct tgaacgaaaa tgaaggacaa
     5041 gctattcaaa caatggatca atctgcctcg ttaattcgtt caaacttaat tcaagttaaa
     5101 gaacaattag aaaaactagc agtttactaa ttaatttatt aaaagctact tgttttcatt
     5161 gagaataagt agctttttca aacacaaaag ttttataaac acataaatgg gtgatgagct
     5221 atgtttaaaa ggacaaaact aatcttaata gcaacaatac tgctatcagg atgttcagcg
     5281 atggaaagtg aatcaaaaaa agacacgaat acagaaacaa aatcagtacc agaagaaatg
     5341 gaagcttcaa aatatgtagg acaaggcttt caaccacctg cagaaaaaga tgcgattgaa
     5401 tttgcgaaga agcatcgtaa agaatttgaa aaagtaggtg aacaattctt taaagataac
     5461 tttggactaa aagttaaagc tacaaatgtt gtaggtaaag atgatggtgt agaagtttat
     5521 gtgcattgtg aagatcatgg tattgtattt aatgcaagtc tacctttgta caaagatgcc
     5581 atccatcaaa aaggatcaat gcgtagtaat gacaacggtg atgatatgag tatgatggtg
     5641 ggtacagtgc tgagtggctt tgaatatcga gcgcaaaaag aaaagtatga taatttatat
     5701 aaatttttta aagaaaatga aaagaaatat caatatacag gttttactaa agaagcaata
     5761 aacaagacgc aaaacgtcgg gtatcaaaat gaatactttt atattacata tttatcaaga
     5821 aacttaaaag aatatcgtaa atattacgaa ccattgattc ataaaaatga taaagaattt
     5881 aaagaaggta tgcaaaaagc tagaaaagag ctaaactata ctgctaatac aaatactgta
     5941 gcaacgttat ttagtacgaa tgatgaaagg aatagaaaag aaaagataaa taatgtaata
     6001 gatttatccg agaaaattga aagaacaaaa gatatgccaa tcaagaatac tataactact
     6061 caattaggaa ataaacttat tggcacaaaa aaagctcgtt ttgatgataa gaaagtagtg
     6121 tcgtttggag catttgaaga tgaatataat aaatgataga gatttaacag aattgagtag
     6181 ttatatggtt tatcaagaca tcaataaaga taataacttt acagttaacg aaaaacgatt
     6241 taagcaggca gatgaatttg aagatttata tagagagaaa ctataagacg caaataaatt
     6301 aagagagtat aattatttac aaaatgaaac ttttaaaagc gcataaatgg gtgatgagat
     6361 atgcttaaaa aggcgaaatt aatcttaata gcaacgctac tgttatcagg atgttcagcg
     6421 atggaaagtg aatcaaaaaa agacacaaaa gcagaaacaa aatctgtgcc agaagaaatg
     6481 gaagcttcaa aatatgtagg tcaaggtttc caaccacctg cagaaaaaga tgcgattgaa
     6541 tttgcgaaga agcatcgtaa agaatttgaa aaagtaggtg aacaattttt tatggacaac
     6601 ttcggtctaa aagttaaagc taccaatgtt gtaggtaaag atgatggtgt agaagtttat
     6661 gtgcattgcg atgatcatgg cattgtattt aatgcaagtt tgcccttgta caaagatgcc
     6721 atccatcaaa aaggatcaat gcgtagtaat gacaatggta atgatatgag tatggtggtg
     6781 ggtacagtgc ttagtggctt tgaatatcga gcgcaaaaag aaaagtatga caatttatat
     6841 aaatttttca aagagaatga aaagaaatat caatatacag gatttacaaa cgaggcaatt
     6901 aacaagacac aaaacgtcgg gtatcaaaat gaatactttt atattacata tttatcaaga
     6961 aacttaaaag aatatcgtaa atattatgaa ccattgattc gtaaaaatga taaagaattt
     7021 aaagaaggta tgcaacgagc cagaaaagag ctaaattata ctgcaaatac tgatgtagtt
     7081 tctacgcttt tttctactaa gaaaaacttt actaaagata atacagtaga tgatgtgatt
     7141 gaattgagta ataaattaaa agataaaccc aatatgcctc aaaaatctca agttactatt
     7201 caattaggaa aatctagtat aaatactaaa aaaccatttt atgacgatat aaatccaatt
     7261 gaagggtaag tgaatataaa gtgaataaaa taaatgatag ggacatagca gaattgaacg
     7321 gttattgggt ttatcaagat ataaatgaat gatagatttt aaagtaaatg aaaaacggtt
     7381 caaacaaata gaaaatcata atatgaaagg cataccttaa tatagaaata tacgagtttc
     7441 ttgatgatca ggggaatcta acttgtcaac agataataat ctatcaagga acttcaaatg
     7501 aggcagtaaa tcctaataac ccattgaaat ctttaggtaa tggagatgat tggcttcaaa
     7561 atgctaaatc aacggataat taaataaaaa tcagacattg tttaacgcaa gtagatgtat
     7621 ttgaagattt atatagagag aaactataag acgtaaataa attaagagag tataattatt
     7681 tgcaaaatga gagttttaaa agcgcataaa tgggtgatga tatatgctta aaaaagcaaa
     7741 attaatatta atagcaacac ttctactatc aggatgttcc atgatgaaaa atgaatcaag
     7801 taaagacacg aatacagaaa ctaaatctgt accagaagaa atggatgctt caaaatatgt
     7861 aggacaagga ttccaaccat ctgcagaaaa agatgcgatt gaattttcga agaagcataa
     7921 agataaaatt gctaagcgag gcgaacaatt ttttatggat aacttcggtc taaaagttaa
     7981 agctacaaat gttataggta gtggcgacgg tgtagaagta ttcgtgcatt gtgatgacca
     8041 cgacatcgta tttaatgcaa gtattccatt tgataaatca attattgaca gtgatagttc
     8101 attaagaagt aaggataaag gcgatgatat gagtacttta gttggtacag tgttgagtgg
     8161 ctttgaatat cgagcacata aggaagagtt ggataattta acagaagttt taaaagaata
     8221 taaaagtaaa tataaatata ctggttatac tgaaaatgca attatgaaaa cgcagaatag
     8281 tggttttaga aatgagtatt attatttgac tgcaattcca tatactttag atgaatataa
     8341 aaagtatttt caacccttaa tcaaagagga tgataagtct tttagggacg gtatgaaaaa
     8401 ctcaaaaaaa caacttaaag ataaatctcg tccatatatt gttacaactt tatttagtac
     8461 taaagataat tttactaaag ataatacaat agacgagatg attgattttt ctgaagtact
     8521 aaaaaagaaa aagaatattc ctcgtgattt gaatgtttct cttcaaattt ctaataaata
     8581 tataaataca aaaagaccta attatagtaa gaaggatgta atagaaatag gtgtatttaa
     8641 tcatgaaaaa gctaacacga atgattaaac taaaaacaat aaaaagatag gttcaaaaaa
     8701 gccatcctaa caacagacaa aaccacaaac caatcaaacc tacccaacca atgaactcaa
     8761 atcaccaatg catcactctc cgataacgta actatgatct tatttaagca tagttattga
     8821 ggttttgtga tatatagtat aaaattaatg agaattaaat ttaataatgt aaaattcatc
     8881 ttcggggtcg ggtgtaattc ccaaccggca gtaaataaag cctgcgacct gctagtatgt
     8941 atcatattag tggctgatct agtgagattc tagagccgac agtatagtct ggatgggaga
     9001 agatggaggt tttttgttgt gcaataatcc tcctattctt acgagatgaa tggaaggaga
     9061 aaattgaata tgcaacaaaa taaacgtctt atcacaataa gtatgttgag cgcgattgcg
     9121 tttgtgttaa cttttatcaa gtttcctata ccatttttgc caccatactt aactttagat
     9181 tttagtgatg taccgtcact actagctaca tttacgtttg gaccagttgc cggtatcgta
     9241 gttgcactgg ttaaaaattt attgaactac ttatttagta tgggcgatcc agttggacca
     9301 tttgctaact ttttagcagg cgcaagtttc ttattaactg cttacgccat ctataaaaat
     9361 aaacgttcaa caaaatcttt gattactgga ttaatcattg caacaatcgt tatgactatc
     9421 gtgttgagta ttttgaacta tttcgttcta ttacctttgt acggtatgat atttaactta
     9481 gctgatatcg caaataatct taaagtaatc attgtttcag gaattatacc attcaatatt
     9541 attaaaggta tcgttatttc tattgtattt attttactat atagaaggct tgcgaatttc
     9601 ttgaaaagaa tttaatcaaa ttaaagcaaa ataatataca cataataata aaaagcaggt
     9661 gactatcaat aaacgatagc ttgcctgctt tttctatgga acatttgtct aaaaaatcaa
     9721 ttattcaaat tttaaagcgt ccccatcaaa tgattcgtct gcaattttaa tagaatctgt
     9781 agggcatcca tcaattgcat cttccatatc ttcatataat tcctcaggca cttctgcagt
     9841 accttggtta tcgtcaagga ttacgaaagc aataccttcg tcgtcgtaat catatatatc
     9901 tggcgctgct gcaccgcatg caccacatgc aatacaagta tccatatcaa cgattgtata
     9961 ttttgccaat gtcttcgcct cctttgataa aaatgctaaa atagtaatgt gactaaaatt
    10021 ttagacagca tcatttttat tttcaaatta tccgttttac agagtgaggg ttaaacttgc
    10081 aacacattat aaaaacagca ttacaacaaa catttaacta taaaacaaat aaaagtattt
    10141 acaatatctt agttggtaag aaatctcacc aaaccttttt tgacgcttgt agtcaacaac
    10201 agttgtcatt atatcacagt ttaccactat taaaatatcc gtcttttgag ctatttttag
    10261 aaaatataac tgaatttaat gctgaaatgg aaatcatgtt gcatcctaga tatacatttg
    10321 aaagtatggg gcaaacattt caagcaattc aactattagt gcaaaccatg tctaatacta
    10381 tgcagcaaga ttttcgtttc gtaccaatct ctcaaaataa taagatacaa gaaactgtaa
    10441 agattgtcta taactatatt aaagaaaacc aattacaaat tgattttgaa aatgaactac
    10501 ataacttgtt taaagcaata actttaaaag ggccatgtta cttacattat tatttgcaag
    10561 gctatgatga accaatgtat acgagacagc aagttagttt aatagaaaag ctatctcaac
    10621 agcaattgtt tgaatacgaa atgaataatt tagtgacaat gatgtttgaa ttagaaagtg
    10681 gagaatatac tattttatca aaaataataa tgaaacctac attattaaac caaacttata
    10741 ttacttatac aagattgctt gaacaattca cgatggaaga tatagcggct caacaacaag
    10801 ttaaaatcaa tactatcgaa gatcatgtac ttgaaatctt aatcaaaggt tatatgtcta
    10861 attacgatga ttatgttgaa caagaagatc aactgcaatt tttaaatttt tatcaacaac
    10921 atcgtggtga acgattaaaa ttttacaaag aacaatttga cacgttatca tattttcaat
    10981 taaaagtatt aatcgttgga tttgaaagag gtgatctgaa tgttgcatga tattttacga
    11041 aacaaatttg gcttcgagaa ttttaaaccg ggacaacagg aaattataga aagtataatg
    11101 tctcaacaac acactctagg tattcttcca actggaagtg gaaagagttt gtgttatcaa
    11161 atacctacgt atttatcagg taagccgaca ttaattatct caccgttaat atctttaatg
    11221 gatgaccaag ttatgcagtt gaaaataaat ggagaaaaac gtgtaacatg tattcactct
    11281 ggtatggatg aaattgagaa aaagcataat attaaatgtt tacgacatag ccgcttcatc
    11341 tttctaagtc cagaatttct cctgcaaccg tcaaatttta aattaatatc tatgatagac
    11401 tttggcatga ttgttctaga tgaagcacat tgcctatctg aatggggata tgatttcaga
    11461 ccacattatg ctctaatagg aaaagtaaca aagcatttta aagaagcggt tgtcttagca
    11521 ttgacagcaa ctgcaccacc gcatttacaa gatgatttga cggaaatgtt agcgattcaa
    11581 ttcaaagtta ttaaaactac aatgaatcgc ccaaacataa gctttaagca tcttaatttt
    11641 catgatgatg aagataaaat tgaatggttg ctgccgtttc tacaacagtc gggaccaacg
    11701 attatttatg tctcatcgaa aaagatgtgt ctgaatttag cgcaccttat ttatgattca
    11761 ggttttctta caggcattta tcatggtgat atgaattatc aagagcgaca cacagttcaa
    11821 caacaatttt taaataatga tattccgatt atagtcgcaa cgagtgcttt tggtatggga
    11881 attaataaaa aagatattcg cacaatcatt cactttcatc tttcaacaag tccttctaac
    11941 tacattcaag aaattggccg tgcgggtcgc gatggtgaac taagtcaggc aattagttta
    12001 tttcaaccgg acgataaata cattttagaa acattattat ttgcagatat gataacagaa
    12061 gaagatgtac aaaatttcga aataggagaa tttttagcac ccgataaaca agacgttttg
    12121 acaacgttgc attcattcta tagtatcggc gccttgaaac agatatttaa gcaatcattt
    12181 aaacgaaagc aattaggatt ctttcgcatg attggctatt gcaaattaga tcaatgtaga
    12241 cgaaagtatt tattagaatt tttcggtgaa tatccaccgg cacaagatcg atgttgtgac
    12301 aatgattcta atataactga tatcgtaatt ttaaataaga agaaggtaat tagaagtatt
    12361 ggatttgatg aaaagttgca aaatttattt ctcagatagt attactttac taaaagaaaa
    12421 ttgacaagct ataattagtg tatacacaat tgaaaaatga ttgaaataat tttgaaaaat
    12481 atacataaac atatgtcatg tgggtatatt ttatgtaaaa tcattgtaat agaatagaaa
    12541 ggaagatggc tatgtctaat aattttaaag atgactttga aaaaaatcgt caatcgatag
    12601 acacaaattc acatcaagac catacggaag atgttgaaaa agaccaatca gaattagaac
    12661 atcaggatac aatagagaat acggagcaac agtttccgcc aagaaatgcc caaagaagaa
    12721 aaagacgccg tgatttagca acgaatcata ataaacaagt tcacaatgaa tcacaaacat
    12781 ctgaagacaa tgttcaaaat gaggctggca caatagatga tcgtcaagtt gaatcatcac
    12841 acagtactga aagtcaagaa cctagccatc aagacagtac acctcaacat gaagaggaat
    12901 attataataa gaatgctttt gcaatggata aatcacatcc agaaccaatc gaagacaatg
    12961 ataaacacga tactattaaa aatgcagaaa ataacactga gcattcaaca gtttctgata
    13021 agagtgaagt tgaacaatct cagcaaccta aaccatattt tacaacaggt gctaaccaat
    13081 cagaaacatc aaaaaatgaa catgataatg attctgtaaa acaagatcaa gatgaaccta
    13141 aagaacatca taatagtaaa aaagcagcag cgatcggtgc tggaacagca ggtttggctg
    13201 gaggcgcagc aagtaaaagt gcttctgccg cttcaaaacc acatgcctct aataatgcaa
    13261 gccaaaacca tgatgaacat gaccatcatg acagagataa agaacgtaaa aaaggtggca
    13321 tggccaaagt attgttacca ttaattgcag ctgtactaat tatcggtgca ttagcgatat
    13381 ttggaggcat ggcattaaac aatcataata atggtacaaa agaaaataaa atcgcgaata
    13441 caaataaaaa taatgctgat gaaagtaaag acaaagacac atctaaagac gcttctaaag
    13501 ataaatcaaa atctacagac agtgataaat caaaagatga tcaagacaaa gcgactaaag
    13561 atgaaactga taatgatcaa aacaacgcta atcaagcgaa caaccaagca caaaataatc
    13621 aaaatcaaca acaagctaat caaaatcaac aacagcaaca acaacgtcaa ggtggtggcc
    13681 aaagacatac agtgaatggt caagaaaact tataccgtat cgcaattcaa tactacggtt
    13741 caggttcacc ggaaaatgtt gaaaaaatta gacgtgccaa tggtttaagt ggtaacaata
    13801 ttagaaacgg tcaacaaatc gttattccat aatataacta tataaattgt aactgaactg
    13861 ctatatacaa acgtgcataa tataaagtaa ctctaaatat tttagagaac ttaaattgcg
    13921 cttataagta tgtagcggtt ttttcctttt tcaaagtttg ttatttaaca aggtgttgtc
    13981 tcggatattg acatataaat taaacttttc aaatagtcat caaaaagata aaacactaca
    14041 atcaacaaat ttaacgagga agaataaaaa ataaatcaac atattaaatt gtagtgttat
    14101 tcaactccgt agctaacaat tctctatgca cattaaacaa attgtcaaaa atatatcata
    14161 aatcttcaag cacagactta gcgtatcaat cactgaactg ttataatagt ttgggattaa
    14221 aggaggccga aacaatgcaa aaagttgaaa gtatcataat tggtggaggg ccatgcggat
    14281 taagtgcggc tattgaacaa aaaagaaaag gtattgatac cttaattatt gaaaagggta
    14341 atgtcgttga atcaatctac aattatccta ctcaccaaac atttttctca tcaagtgata
    14401 aattaagtat tggggacgta ccgtttatcg ttgaagaaag taaaccaaga cgtaatcaag
    14461 cgctagttta ttaccgagaa gttgtaaaac atcatcaatt aaaagtaaat gcatttgaag
    14521 aagtattaac tgttaaaaaa atgaataata aatttacaat tactacgacg aaagatgttt
    14581 atgaatgtcg atttttaaca atcgcgacag gctattatgg tcagcataat acattagaag
    14641 ttgaaggtgc ggatttacct aaagtgttcc attattttaa agaggcacat ccgtattttg
    14701 atcaagatgt tgttattatt ggtggtaaga attcggctat cgatgctgct ttggagttgg
    14761 aaaaagctgg tgctaacgtg acggttctat atcgtggtgg agattattca ccttcaatta
    14821 aaccgtggat acttccaaat ttcacagcat tagtaaatca tgaaaaaatt gacatggaat
    14881 ttaatgctaa tgttacccaa ataactgaag atactgtgac ttatgaagta aatggtgaaa
    14941 gtaaaacgat acacaatgat tatgtatttg cgatgattgg ttatcatccc gattatgaat
    15001 ttttaaaatc tgtaggcatt caaattaata caaatgaatt tggaacagcg cctatgtata
    15061 ataaagaaac atacgaaaca aatatcgaaa attgctacat tgcaggtgtg attgctgcag
    15121 ggaatgatgc gaataccatt tttattgaaa atggtaaatt ccacggtggc attattgctc
    15181 aaagcatgct agctaagaaa caaacgccgt tagaatcata aaaacaaagg tctatgtact
    15241 agataactta gttttacaac gactgacatt catgatatgt caaatgaggt tgatgactaa
    15301 ttattgtaca tagacctttt tatattacgt aatcattata attcaaaata tgatttgatt
    15361 tcagctttat ctaaattgtt gcttaacgca actaataatt ttaatcttgc ttttggacca
    15421 ttcaaaccgt tagaaaaaat aaaaccttgt tgtgcgagtt ggtaaccacc accatcgtat
    15481 gcgtaagttg gactcacaat accattaaag gaacgtgaaa ctagcacaat aggtatattt
    15541 aaagatacta attgttgaat gccttctaat gcgcttggag gtatgttgcc ttgtcctaac
    15601 gcttcaataa ccataccatc gataccttca cgactataaa aactaaaaat gtcacctggc
    15661 atacccatat atgcttttac taatggtaca tttagtttct cattgacatt ttccaatgct
    15721 tgttggcgat atggcatatg atggaattgc acacgatcct ttgtcaatac acctagcgga
    15781 ccatgatttg gactttgaaa tgtgtttgta ttagacgtat gtgttttggt aacattacgc
    15841 gccgtatgaa tttcatcatt aaatacaacc atcacgcctt tatgacgagc cttttcatca
    15901 gaggcaacgc gaatagcgga aatataatta tataatccgt cagaaccaat ttcattagac
    15961 gagcgcattg cgccagtaat aacaacaggt tgctcgatac ctaatattaa atcaagtaaa
    16021 aaggcagttt cttctaacgt atcggtacca tgcgtgataa cgaaaccatc ataatattta
    16081 tttgatactg cttctaaaat aatatccttt aattgtttaa catgttggat tgtcatatga
    16141 ggtgatggta cattaaaagg atttaattca tctatttgtg catattgatt tatgacatct
    16201 tgatgcattg aaatagggtt gatatcattt gttactactt tattagattg gtcttgtgac
    16261 atactaatgg tgccaccagt atgaataacc agtagatgtt tcatatattt cctcctatat
    16321 ttcatttacc taattatgat aaaatattat tcataaaacg acaaggaagg gaaatgacgc
    16381 atgaaagcca ttaatattgc attagatggt ccagctgctg ccggaaaaag tacaattgcg
    16441 aaacgtgtag ccagcgaact atcaatgatt tatgtcgata caggagcaat gtatcgtgca
    16501 ttaacataca aatatttaaa attaaacaaa actgaggact ttgcaaaact agttgaccaa
    16561 acaacattag atttaactta taaagcagat aaaggtcaat gtgtcatttt agataacgaa
    16621 gatgtaacag actttttaag aaataatgat gtgacgcaac atgtttcata cgttgcatct
    16681 aaagagccag tacgttcatt cgccgttaaa aaacaaaaag agttagctgc agaaaaaggt
    16741 atcgtaatgg atggtcgcga tatcggaact gtagtgctac cagatgcaga tttaaaagta
    16801 tatatgattg catcagttga agagcgagca gaaagaagat ataaagataa tcaattaaga
    16861 ggtatcgaat caaattttga agatttaaaa cgtgatattg aagctcgtga tcaatatgac
    16921 atgaaccgtg aaatatcacc attaagaaaa gcagatgatg cagtgacatt agatacgaca
    16981 ggcaagtcga ttgaagaagt tactgacgaa attttagcga tggtgagtaa aattaaataa
    17041 tctaataagt cataactatc tatttgtaat gtgcaacgct taacgcatat acaaaatgaa
    17101 tgtgctgaga atgatttact caaattaaaa ggtgattttt attcaatgat gaatgaaagt
    17161 tgccttttta tttttggtaa aagttaatgc gtcagtgaat tgtgtaagtt tttcaaaaag
    17221 taaaaagaaa taataaaggt gaattattag aattccaaaa ataattcatt acattcataa
    17281 agcattttac aaatggtaag aaaatgagtg ttacaaatct aaatattgca aaagaagctg
    17341 atttagtcac aaaaaatgtc ctatgtaata attcgagaaa gatgcactat atacagtctt
    17401 cttactattc aaatgtaaaa gttgcttatt tgcgtggctt tttgttttat aaaagtataa
    17461 aattttacta taatatatct tgtagagaac aatgaaatga cagacttata aaacaaaata
    17521 gtaagctatg ctaattttta tacaaaaaat atgtataaac atagcggact ttattacttg
    17581 tttgaatata tggttgtaat aaatatatgt ccaactaatt cacagaatga gattaagtga
    17641 catatttatg gatacaacta atttactaaa tgtaataaag gtagaatttc ttgacaattc
    17701 tgtcagttta taagatgtta taaatatgta gtgtataagg aggcaaacaa gatgactgaa
    17761 gaattcaatg aatcaatgat taacgatatt aaagaaggtg acaaagtcac tggcgaggta
    17821 cagcaagttg aagacaagca agttgttgtt catatcaatg gtggtaaatt taatgggatt
    17881 attcctatta gtcaactatc tacgcatcat attgatagcc caagtgaagt tgtaaaagag
    17941 ggcgacgaag ttgaagcata tgtcactaaa gttgagtttg atgaagaaaa tgaaactgga
    18001 gcttacatct tatctagaag acaacttgaa actgagaagt cttatagtta tttacaagaa
    18061 aaattagata ataatgaaat catcgaagcg aaagtaacag aagtagttaa aggtggtttg
    18121 gttgttgatg taggacaaag aggttttgtt ccagcttcac taatttcaac agacttcatt
    18181 gaggatttct ctgtatttga tggacaaaca attcatatta aagttgaaga attggatcct
    18241 gaaaataata gagtcatttt aagccgtaaa gcagttgaac aagaagaaaa tgatgctaaa
    18301 aaagatcaat tattacaatc tttaaatgaa ggcgatgtta ttgatggtaa agtagcacgt
    18361 ttaactcaat ttggtgcatt tatagacatt ggcggtgttg atggtttagt gcatgtatct
    18421 gaactttctc acgaacatgt tcaaacacca gaagaagtag tttcaattgg tcaagatgtt
    18481 aaagttaaaa ttaaatctat tgatagagat acagaacgta tttcattatc aatcaaagat
    18541 acgttaccaa cacctttcga aaatattaaa ggtcaattcc acgaaaatga tgtcattgaa
    18601 ggtgtcgtag taagattggc aaactttggt gcatttgtag aaattgcacc aggtgtacaa
    18661 ggacttgtac atatttctga aattgcacac aaacacattg gtacgccagg tgaagtgtta
    18721 gaacctggtc aacaagtaaa tgttaaaata ttaggtattg atgaagagaa tgaaagagta
    18781 tcactatcta ttaaagcaac attaccaaac gaagatgttg ttgaaagtga tccttctacg
    18841 actaaggcgt acttagaaaa cgaagaagaa gataatccaa caattggcga tatgattggt
    18901 gataaactta aaaatcttaa actataattt aatatttaat agtcaactcc acatgtttat
    18961 gattgcatgt ggagtatttt tttgtaccaa aatatactcg gaatgataac gtggacaaat
    19021 ttaactaagt gtttaaagag ataaagtttt aagtgctgat ttttatcatt acagtaataa
    19081 actcattttg aatacacagt ctcatgtgat attattaaaa agatataaga aagagaggaa
    19141 gttagcttat gactaaacct atagtagcta ttgtaggtag gcctaatgta ggtaaatcta
    19201 caatttttaa tagaatagtt ggagaacgtg tttcgattgt ggaagacacg ccaggtgtaa
    19261 cacgagatcg tatttattct tcaggtgaat ggttaacaca tgatttcaat attattgata
    19321 caggtggtat tgaaattggt gatgcaccat tccaaacaca aattagagcg caggcagaaa
    19381 tcgccataga tgaagcggat gttattattt ttatggttaa cgtgcgtgaa ggattgacac
    19441 aaagcgatga aatggtcgct caaattttat acaaatctaa aaaaccggtc gtattagcgg
    19501 ttaacaaagt agataatatg gaaatgcgta cagacgtgta tgatttctat tcattaggat
    19561 ttggtgaacc gtatccgata tcagggtcac atggtttagg tcttggtgac ttgttagatg
    19621 cagttgtttc tcattttggt gaagaggaag aagatcctta tgatgaagat acaattcgac
    19681 tatccattat tggacgacca aacgtaggta aatcaagttt agtaaatgct attttaggtg
    19741 aagatcgcgt tatcgtttct aatgttgcag ggacaacgag agacgctatt gatacagagt
    19801 atagttatga tggacaagat tatgttttaa tcgatactgc tggtatgcgt aaaaaaggaa
    19861 aagtatatga atcaactgag aaatattcag tactaagagc tttaaaagcg attgaacgtt
    19921 caaatgttgt tttagtggtc attgatgcag aacaaggcat cattgaacaa gataaacgcg
    19981 ttgcaggata tgcacatgaa caaggtaaag cagtcgtgat tgtcgtaaat aaatgggata
    20041 ctgtggaaaa agatagtaaa acgatgaaga aatttgaaga tgaagtacgt aaagaattcc
    20101 aatttttaga ttatgcacaa attgcttttg tgtctgctaa agaacgcaca agattacgta
    20161 cattattccc ttacattaat gaagcaagtg aaaaccataa aaaacgtgtt caaagttcaa
    20221 ctttaaatga agtcgttact gatgcaattt ccatgaaccc tacaccaaca gacaaaggta
    20281 gacgtttgaa tgtcttttat gcaacacaag ttgctataga accaccgaca tttgttgtat
    20341 ttgttaatga tgtagaatta atgcattttt cttataaacg ctatttagag aatcaaatcc
    20401 gtgccgcttt tggttttgaa ggtacaccaa ttcatattat agctcgaaag agaaattaac
    20461 gattggggga taacaatgac taaaattacc gtttttggta tgggaagttt tgggacagcc
    20521 cttgccaatg ttcttgcaga aaatggacat gatgttttga tgtggggtaa aaatcaagat
    20581 gctgttgatg aattaaatac atgtcataca aataaaaagt atttaaaata cgcgaaatta
    20641 gatgttaaca tcatcgctac ttcagatatg accaaagcaa ttcaatttgc agatatttac
    20701 ttaatggctt tacctactaa agcaatgcga gaagttgcta ctcaaattaa tgataagctg
    20761 acctctaaaa agacttttat acatgttgct aaaggtattg aaaatgggac gtttaaacgt
    20821 gtgtcagaaa tgattgaaga ttctatttca cccgaatata atgcaggtat tggcgtgttg
    20881 tcagggccaa gtcatgcgga agaagttgta gtcaagcaac caactacagt tgctgcatca
    20941 tcaaaagata aaagtgtaag taaattaacg caagatttat ttatgaatga ttatttgcgt
    21001 gtgtacacga atgatgactt gattggtgtt gaacttggtg gtgcattgaa aaatatcatc
    21061 gcagtagcaa gtggtatcgt agctggaatt ggctacggtg ataatgcaaa agctgcgtta
    21121 atgactcgtg gtttagcgga aattagtaga ttaggtgaaa agttaggtgc cgatcctatg
    21181 acatttctag gtttaggtgg tatcggtgac ttaatcgtta cttgcacatc aacacattct
    21241 cgaaatttca cattaggata taaacttgga caaggtgaat caatggatca agcattatct
    21301 gaaatgaata tggttgttga aggtatttat acaactaaat cagtttatca tttagctaaa
    21361 gaaaaaaatg tggatatgcc aattacaaat gcattatata gagtattatt tgaaaatatc
    21421 tcagtaaaag aatgcgtaaa agatttaatg gagcgcgata aaaaatctga ataaaatgtg
    21481 tattattaca catatacggc taataattac gtaaaatgaa tagaaatggc ttaaattcaa
    21541 cgtttttgcc acataaatga ttgcgattta tgtaatgctt gtgttaaagt tttaccataa
    21601 tgatataaac atatcattat caaacctcag gaggtgaatg tctaatgaac aaaacagatt
    21661 taatcaatgc agttgcagag caagctgatt taactaaaaa agaagctggt tcagcagtag
    21721 atgctgtatt cgaatcaatc caaaactcac ttgctaaagg tgaaaaagta caattaattg
    21781 gtttcggtaa ctttgaggta cgtgaacgtg ctgcacgtaa aggtcgtaac cctcaaactg
    21841 gtaaagaaat tgatatccca gcaagtaaag ttccagcatt caaagctggt aaagcattaa
    21901 aagatgctgt aaaataattt tacttaaaaa gccctgaata agggcttttt attttgcttt
    21961 taatacttac aacctgtaca taatttgt
//
LOCUS       DAPSKH010000048        21117 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPSKH010000048 DAPSKH010000000
VERSION     DAPSKH010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21117
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.048"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(19..846)
                     /locus_tag="RPH49_001916"
     CDS             complement(19..846)
                     /locus_tag="RPH49_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5125056.1"
                     /translation="MWKWEAENDAKGVVVIAHNILEHTGRYAYVITMLRRNGYHVIMG
                     DLPGQGQTSRANKGQIENFQTYHESLLDWLKIANEYKIPTYVLGVGLGGLILLNLLEK
                     VELPIEGMMLISPMLELQKNGKNRKDKLVSNIGKISKDARFNVGVEPKDLTRNLEIVE
                     ETVNDGLMLKKATYHWYNTINETMKDTMAHIHDIQPMPTLLMYGTKDLIVDTRAIDEF
                     KEKYQTPELYFKAWQGFYHEVHNEPERDEVMRYILTFLNNSVNTMGFIVEDDEIVEI"
     gene            complement(849..968)
                     /locus_tag="RPH49_001917"
     CDS             complement(849..968)
                     /locus_tag="RPH49_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125057.1"
                     /translation="MMLISFIYNNMDNNNTINRNLHSEFAIIMLLKINEKGAV"
     gene            1080..2081
                     /locus_tag="RPH49_001918"
     CDS             1080..2081
                     /locus_tag="RPH49_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline dehydrogenase"
                     /protein_id="HDY5125058.1"
                     /translation="MALLKNFFIGLSNNSFLNNAAKKVGPRLGANKVVAGNTIPELIN
                     TIEYLNDKNIAVTVDNLGEFVGTVEESNHAKEQILTIMDALHQHGVKAHMSVKLSQLG
                     AEFDLELAYQNLREILLKANTYNNMHINIDTEKYASLQQIVQVLDRLKGEFRNVGTVI
                     QAYLYDSHELVDKYQDLRLRLVKGAYKENESIAFQSKEDVDANYIKIIEQRLLNARNF
                     TSIATHDHRIINHVKQFMKENHIEKDRMEFQMLYGFRSELAEEIANEGYNFTIYVPYG
                     DDWFAYFMRRLAERPQNLSLAVKEFVKPAGLKRVGIIAALGATVMLGLSTIKKLCRK"
     gene            complement(2203..2667)
                     /locus_tag="RPH49_001919"
     CDS             complement(2203..2667)
                     /locus_tag="RPH49_001919"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDY5125059.1"
                     /translation="MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNE
                     DNIDVAFVPGAFEIPLVAKKLASSGNYDAVITLGCVIRGATSHYDYVCNEVAKGVSKV
                     NDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA"
     gene            complement(2680..3861)
                     /gene="ribB"
                     /locus_tag="RPH49_001920"
     CDS             complement(2680..3861)
                     /gene="ribB"
                     /locus_tag="RPH49_001920"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HDY5125060.1"
                     /translation="MQFDNIDSALMALKNGETIIVVDDDNRENEGDLVAVTEWMNDNT
                     INFMAKEARGLICAPVSKDIAQRLDLVQMVDDNSDIFGTQFTVSIDHVDTTTGISAYE
                     RTLTAKKLIDPSSEAKDFNRPGHLFPLVAQDKGVLARNGHTEAAVDLAKLTGAKPAGV
                     ICEIMNDDGTMAKGQDLQKFKEKHQLKMITIDDLIEYRKKLEPEIEFKAKVKMPTDFG
                     TFDMYGFKATYTDEEIVVLTKGAIRQHENVRLHSACLTGDIFHSQRCDCGAQLESSMK
                     YINEHGGMIIYLPQEGRGIGLLNKLRAYELIEQGYDTVTANLALGFDEDLRDYHIAAQ
                     ILKYFNIEHINLLSNNPSKFEGLKQYGIDIAERIEVIVPETVHNHDYMETKKIKMGHL
                     I"
     gene            complement(3872..4504)
                     /locus_tag="RPH49_001921"
     CDS             complement(3872..4504)
                     /locus_tag="RPH49_001921"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDY5125061.1"
                     /translation="MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVN
                     GACLTVIDFNQTSFTVQVIKGTENKTYLADVKRQSEVNLERAMSGNGRFGGHFVLGHV
                     DELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLI
                     PETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF"
     gene            complement(4511..5554)
                     /gene="ribD"
                     /locus_tag="RPH49_001922"
     CDS             complement(4511..5554)
                     /gene="ribD"
                     /locus_tag="RPH49_001922"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDY5125062.1"
                     /translation="MSQFMDYAIQLANMVQGQTGVNPPVGAVVVKEGRIVGIGAHLRK
                     GDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKITKVVYATKDNS
                     LDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDN
                     GQSQWITNKEVKQDVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSG
                     NIHFNQQIYQDESTPIWIYTENPNLTTKQTHIEIIFLESCDLTTILHNLYKRGVGTLL
                     VEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHSE
                     LLNQNVKLTLRKK"
     regulatory      complement(5681..5816)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(6035..7537)
                     /locus_tag="RPH49_001923"
     CDS             complement(6035..7537)
                     /locus_tag="RPH49_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDY5125063.1"
                     /translation="MRVAIIGMGTAGVSVLRELVKHPKFNQLDIDLYDDKVNMGQGVP
                     FQNDSSELLINMPSKKMSLNLDDETEFWKWYKQQTDFNFDEPAYLPRFVFGHYMKSYL
                     SMFTKKYPNISTNYNKVQEIYTNSNIDETNLTYYICTTNSGQSWQAYDYVFLTCGTFA
                     YHDPYNLKGKKGYIATPYPTYNTLDEVNELDDIAIIGTGLASLDVVRYVAAHHPKLPI
                     TMTSRSAHLPSVRGTMIDVTFKYLTKDKLNDIKKHHFGNAPLDTLVSLFLKECAEYDI
                     DFKKLVHRRTGNHIADLKYDLARPTEMGIFQSMIEHLKENLNWIWNSLSIEDQHQFNQ
                     KYSKMIQLNSNPMPPRTAELIIELIENKSLILKKDLEDVKHDGKLYYFSYKNQESVDI
                     YNVVINATGAKSHLNELDQDDQLIKNLENRQIVQAHSMGGIQIIPETNQVISPRFGTL
                     TNMIAIGQMTNGVNKLRNGVKMIVEQVAHTVSQLYDALESNEQQQRSDNQ"
     gene            8064..8378
                     /locus_tag="RPH49_001924"
     CDS             8064..8378
                     /locus_tag="RPH49_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDY5125064.1"
                     /translation="MTYKELATYLKVLSDSSRLEILDLLSCGELCACDLLEHFQFSQP
                     TLSYHMKALVKTNLVTTRKIGNKHLYQLNHNIFESVINNLSKVHTSNQRCICHNLKTG
                     EC"
     gene            8378..9670
                     /gene="arsB"
                     /locus_tag="RPH49_001925"
     CDS             8378..9670
                     /gene="arsB"
                     /locus_tag="RPH49_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite efflux transporter membrane subunit
                     ArsB"
                     /protein_id="HDY5125065.1"
                     /translation="MMTTLATLIFLVTLLFVLWQPKGLDIGFTALAGAIVAMITGVVS
                     LTDVFEVTGIVWNATLTFVSVILISLILDKIGFFEWSAIHMLHASKGNGLKMFVYIIL
                     LGAVVAAFFANDGSALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSN
                     LVNIISADYFNISFSQYLSRMIIPNLFSLLGSLLVLWLYFRKAIPKSFDANHIKKPKD
                     AINDLKLFKISWIVLVILLFGYLISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQV
                     IKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLFSTILGMGFISAFLS
                     SIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVL
                     TQKDVKISWGTYFKTGITITIPVLFITLLGLYLTLIIF"
     gene            9688..10083
                     /gene="arsC"
                     /locus_tag="RPH49_001926"
     CDS             9688..10083
                     /gene="arsC"
                     /locus_tag="RPH49_001926"
                     /EC_number="1.20.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (thioredoxin)"
                     /protein_id="HDY5125066.1"
                     /translation="MTKKTIYFICTGNSCRSQMAEGWAKQILAKDWDVYSAGIETHGV
                     NPKAIEAMKEVGIDISNHTSDLIDNNIIKNSNLVVTLCSDADVNCPTLPTNVKKEHWG
                     FDDPAGKPWSEFQRVRDEIKVAIENFKSR"
     gene            complement(10713..11855)
                     /locus_tag="RPH49_001927"
     CDS             complement(10713..11855)
                     /locus_tag="RPH49_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125067.1"
                     /translation="MIKKSLIVPLYINIFLVFTAISLVVPSLPLIIKDLNIDGDAFGI
                     LIAVFSLFQMIFSPIVGFFSDRYAKKHFLSIGLLLYIVSEFLFGIGMGFYTLLSSRIL
                     GGISAALIQTSVIGIIGDISDEANRDKNFGTFSAITSLGFIIGPGIGALFATFHLRLP
                     YFIAMAIGIIMLIINLNLKIPHVQTLASKENKLATLSFKYLKLYLLPAMVILLLAFGL
                     AAIEELYPLYLVDKADFTSFHIALAIIGGSLLGALTQYLVYPKISRHLHEFSIIIISS
                     IYSIMVLCILLLLNSVIALVLISCVIFIGFDIIRPAITVYLSKIAKDKQGLAGSMNST
                     FTSLGTLIAPIIAGYFYVQNINAPVYIAILTIILTIIALIFLPKKE"
     gene            complement(12175..12717)
                     /locus_tag="RPH49_001928"
                     /pseudo
     CDS             complement(12175..12717)
                     /locus_tag="RPH49_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251209.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(13347..14201)
                     /locus_tag="RPH49_001929"
     CDS             complement(13347..14201)
                     /locus_tag="RPH49_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosaminidase"
                     /protein_id="HDY5125068.1"
                     /translation="MNKHKKGSIFGIIGLVVIFAVVSFLFFSMISDQIFFKHVKSDIK
                     IEKLNVTLNDAAKKQINNYTSQQVSNKKNDAWRDASATEIKSAMDSGTFIDNEKQKYQ
                     FLDLSKYQGIDKNRIKRMLVDRPTLLKHTDDFLKAAKDKHVNEVYLISHALLETGAVK
                     SELANGVEIDGKKYYNFYGVGALDKDPIKTGAEYAKKHGWDTPEKAISGGADFIHKHF
                     LSSTDQNTLYSMRWNPKNPGEHQYATDIKWAESNATIIADFYKNMKTEGKYFKYFVYK
                     DDSKHLNK"
     gene            complement(14477..14701)
                     /locus_tag="RPH49_001930"
     CDS             complement(14477..14701)
                     /locus_tag="RPH49_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125069.1"
                     /translation="MDYAHLNLEHFFARNDDLDVIRDRADFVMINNFTNEMMYRDGQI
                     EGTIDLNQYYYKNRSNAASFIMMDYKKETK"
     gene            14900..15370
                     /locus_tag="RPH49_001931"
     CDS             14900..15370
                     /locus_tag="RPH49_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDY5125070.1"
                     /translation="MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQI
                     YKPSSKQSLSSFLFMRLNFYLIDLFRQQKRLNDIILYENHSPILTEQPIYFNEFNLNL
                     QDVCALLNHRERQWLMLYLEGYKQYEIADIMSLSTSTIKLIKASVKRKCQRFFK"
     gene            15483..15926
                     /locus_tag="RPH49_001932"
     CDS             15483..15926
                     /locus_tag="RPH49_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComK"
                     /protein_id="HDY5125071.1"
                     /translation="MQDISTKHLLYIQTATSNHLETKCVFLYHEYNLEFPITKAIPYY
                     AKLHFTSASILIDAAKSILNINKLVPIYLNPKTILFPIKQKRAPIQTYINAHYVIGMT
                     EMGNSTMLHFKNGKTLEVDEPMSLISKKCHESLALKHFIENTNDH"
     gene            complement(15913..16356)
                     /locus_tag="RPH49_001933"
     CDS             complement(15913..16356)
                     /locus_tag="RPH49_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125072.1"
                     /translation="MNKASFDKKVKKQLWFLNKKEKHALDQRLSSITDKDNVNFNKPI
                     TFANAYLRENVFRSKETKSYSIFVTLVVMMFAYVALLGLFLFGLITSLSGVQFFVNPK
                     VELSTTVVILTIIGAILLMLVSIYLIKITTSYFTKKLIEHKFNGH"
     gene            16654..17289
                     /locus_tag="RPH49_001934"
     CDS             16654..17289
                     /locus_tag="RPH49_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDY5125073.1"
                     /translation="MQKFKDLFYDDLSVARGNYFLTLLYAFLITIILLIGFVVSNTHI
                     LYGMFIVLIGIVLLRLFKINLLSFKKLTMSQVIYIIGGALLIYGLDHLYLHFHDVPTN
                     EQELDRELQHTPLYMSIVTIAIIPAIVEEIVFRGMIIRVVFRKHLFIGLVVSSLVFAS
                     LHESDTWIGYLPYLYSGVIFGLIYLKTKRLEVVILIHFINNLSSLLILIWG"
     gene            17456..18076
                     /locus_tag="RPH49_001935"
     CDS             17456..18076
                     /locus_tag="RPH49_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDY5125074.1"
                     /translation="MFSRNNNIFVDDLSVTKDNYLIAVLKMLVIFLVINYGTDVSYDH
                     EYVGLFIILLGVVLLKVLNINLLSFKKLKFTHMLYIIFGFLLMYGLDYLYDMFAPPTL
                     NEILLDEESEDAPYHIALLSTAIIPPITEEIICRGLIIRILFRNHLFLGFIVSTVFFT
                     LIHEPDTLIGYLPYFYSGLIFGYTYLKTKRLEVPILIHFINNLLAM"
     gene            complement(18473..19186)
                     /locus_tag="RPH49_001936"
     CDS             complement(18473..19186)
                     /locus_tag="RPH49_001936"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDY5125075.1"
                     /translation="MAKLNVEVFADGADIEEMKAAYKNKQVDGFTTNPSLMAKAGVTD
                     YKAFAEEAVKEIPDASISFEVFADDLETMEKEAAILKQYGENVFVKIPIVNTKGESTI
                     PLIKKLSADNVRLNVTSVYTIEQVKEITEAVTEGVPTYVSVFAGRIADTGVDPLPLMK
                     EAVKVTHSKDGVKLLWASCRELFNVIQADEIGADIITCPADVVKKVNTNLGRDINELS
                     VDTVKGFAKDIQSSGLSIL"
     gene            19445..19747
                     /locus_tag="RPH49_001937"
     CDS             19445..19747
                     /locus_tag="RPH49_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125076.1"
                     /translation="MSRSKKYFYLSSLMIILSFFFNTNNVFLSGLFNSFIKLILFCSV
                     INSIILILSIIFADRSIKSLKPDADWIRIASKSLPWIILIVILVHIFSIVHTFGFI"
     gene            20003..20368
                     /gene="crcB"
                     /locus_tag="RPH49_001938"
     CDS             20003..20368
                     /gene="crcB"
                     /locus_tag="RPH49_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDY5125077.1"
                     /translation="MQYVYIFIGGALGALLRYLISFLNTDGGFPIGTLIANLTGAFVM
                     GLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAITS
                     YVFGILLCYVGIKLGGGLS"
     gene            20365..20718
                     /locus_tag="RPH49_001939"
     CDS             20365..20718
                     /locus_tag="RPH49_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CrcB family protein"
                     /protein_id="HDY5125078.1"
                     /translation="MISIILVMIGGGLGAIARSAVTDYFNHKFTSKLPIATLIVNLVG
                     SFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLAKELTLMMMPKFNINLFLNYSLL
                     QFIIGFIACYIGYHI"
BASE COUNT         6887 a         3698 c         2943 g         7589 t
ORIGIN      
        1 tctcatcttt ttagaatatt aaatttctac aatttcgtca tcttcaacaa taaagcccat
       61 tgtattgacg ctattattta agaaagtcag aatataacgc attacttcat cgcgttctgg
      121 ctcattgtga acctcgtggt aaaaaccttg ccaagcttta aaatataatt caggtgtttg
      181 atatttttct ttaaactcat caattgccct agtatcaaca attaaatcct tcgttccata
      241 cattaatagc gttggcattg gttgaatgtc atgaatatga gccatcgtat ctttcatcgt
      301 ctcattaatt gtattatacc aatgatacgt tgcttttttt aacattaaac catcgttaac
      361 tgtttcttca acaatttcta aattacgtgt taaatctttt ggttctacac caacattaaa
      421 acgtgcgtct tttgaaattt tacctatatt tgaaacaagt ttatctttac gattttttcc
      481 attcttttga agttctagca taggagaaat taacatcatc ccctcgattg gcaattctac
      541 tttttcaagt aaatttaata aaatcaaacc gccaagtcct acccctaata cataagtagg
      601 aattttatat tcattagcta tctttaacca atctagcaaa ctttcgtgat acgtttgaaa
      661 gttttcaatt tgtcctttat tagctcttga agtttgacct tgaccaggca aatctcccat
      721 aatcacatga tagccatttc ttcttaacat cgtaataaca tatgcatatc ttcccgtatg
      781 ttctaatata ttatgagcaa taacaacgac gcctttcgca tcattttcag cttcccactt
      841 ccacattatt atactgcccc tttttcatta atcttcaata acataattat agcaaattca
      901 ctatgtagat ttctatttat agtattattg ttgtccatat tattatatat aaatgaaatc
      961 aacatcaata atagtgtaat tatacataat tatttttgat tgtttttgat gaaaacgctt
     1021 tctcgaatat ttttttcatg ctaaacttat tgtaaacaca agggtttgga ggagtagcaa
     1081 tggcactatt aaagaatttt tttatcggat tatctaataa tagtttttta aacaacgcag
     1141 caaaaaaagt gggcccacgt ttgggcgcca ataaagtcgt tgccggaaat acaattccag
     1201 agttaattaa tacaatcgaa tacttaaatg acaagaatat cgctgttacg gtagacaatt
     1261 taggggaatt tgtcggtaca gttgaagaaa gtaatcatgc taaagaacaa attttaacaa
     1321 ttatggacgc gcttcatcaa catggcgtaa aggcacatat gtctgttaaa ttgagtcagt
     1381 taggtgcaga attcgactta gaattagctt accaaaattt aagagagatt ttacttaaag
     1441 caaatactta caacaatatg catataaata ttgatactga aaaatatgct agcctgcaac
     1501 aaattgttca agttttagat cgcttaaaag gcgaatttag aaatgttggt actgtaattc
     1561 aagcatattt atacgatagc catgaattag ttgataagta ccaagattta cgattacgtt
     1621 tggttaaagg tgcatataaa gaaaacgaat caattgcatt tcaatctaag gaagacgtag
     1681 atgcaaatta catcaaaata attgaacaac gtttgttaaa cgcacgcaat ttcacttcaa
     1741 ttgcaacaca tgaccatcgc atcattaatc atgtaaaaca atttatgaaa gaaaatcaca
     1801 ttgaaaaaga tcgtatggaa ttccaaatgc tctatggttt tagatcagag ttagcagaag
     1861 aaatcgcaaa tgaaggctat aatttcacta tttatgtacc ttatggcgat gattggtttg
     1921 cgtattttat gagaagatta gcagaacgcc cacaaaacct atctcttgct gtaaaagaat
     1981 ttgtgaaacc tgctggctta aaacgtgttg gcataattgc agctttagga gctacagtta
     2041 tgttaggttt aagtacaatt aaaaaattat gccgtaaata gagcatggca taaacaataa
     2101 tttaggagtc tggaacaata atcaatgttc taggctccta aatgttatat tggcagttct
     2161 gaatcattta taaatctttg attatgaact cacaacagcg ctctatgctt ttatagattt
     2221 taataaatta gccatttcaa ttgcacttac tgctgcttcg gcacctttat tgccagcttt
     2281 cgtacctgct ctttccacag cttgttcaat actttcagtc gttaaaatac caaatatgac
     2341 tggtacatta gtttgatcat ttactttaga aacacctttc gcgacttcat tacaaacata
     2401 atcataatga gacgtagcac cgcgaattac gcatcctaat gtaattactg catcataatt
     2461 tcctgatgag gctaatttct tagctactaa aggaatttca aacgcaccag gaacaaatgc
     2521 tacatcaata ttgtcttcat taacatcatg tcgaatcaaa gtatcttttg caccttcaag
     2581 taatcttcca gtgataaaat cattaaatcg actaactacg attgcaactt tcaaatcttt
     2641 tccaattaat ttaccttcaa aattcatgtt aaagtcctcc tatattaaat gacccatttt
     2701 tatttttttc gtttccatat aatcatgatt atgtaccgtt tctggtacga taacttcaat
     2761 tctttctgca atatcaatgc catattgttt taatccctca aatttacttg gattattact
     2821 taataaattg atatgttcga tgttaaaata ttttaaaatc tgtgcagcaa tatgataatc
     2881 tcgtaaatct tcatcaaaac ctaatgctaa atttgcagtt actgtatcat atccttgctc
     2941 aattaattca tatgcgcgta atttgtttaa caatcctatg ccacgacctt cttgaggtag
     3001 ataaataatc atgccaccat gttcattgat atacttcata gacgattcaa gttgagcacc
     3061 acaatcacaa cgttgactat ggaaaatatc gcctgtaagg cacgcagaat gtaagcgtac
     3121 attttcatgt tgtcgaattg caccttttgt cagtacaact atctcttcat ctgtgtatgt
     3181 cgctttaaaa ccatacatat caaatgttcc gaaatctgta ggcattttca cttttgcctt
     3241 aaattcaatt tctggttcta attttttacg atattcaatt aaatcatcaa tcgtaatcat
     3301 ctttaattga tgtttttctt taaacttttg taaatcttgt cctttcgcca tcgtgccgtc
     3361 atcattcata atctcacaaa tgacaccagc gggcttggca ccagtaagtt tagctaaatc
     3421 aacagccgct tctgtgtgtc catttctagc taatacgcct ttatcttgtg ctactaatgg
     3481 aaataaatga ccaggacgat taaaatcttt agcttcacta ctaggatcaa tgagcttttt
     3541 ggcagtcaat gtacgttcat aagcactaat tcctgttgtt gtatctacat gatcaatact
     3601 cactgtaaat tgcgtaccaa agatgtcgga gttatcatca accatttgta ccaaatccaa
     3661 acgttgtgca atatctttag acactggtgc gcatattaat ccccttgctt ctttcgccat
     3721 aaaattaatg gtattatcgt tcatccattc agtaaccgct actaaatcac cttcattttc
     3781 acgattgtca tcatctacta caataattgt ttctccattt tttaaagcca ttaaagcact
     3841 gtcaatatta tcgaattgca tgctacccct cctaaaaacc aaatgctctt aatttatcta
     3901 cagataattg gtctttatct ttatttaaaa tattttcaac atatttaaac aaaacgtctg
     3961 tttctaaatg tactttatct cctaattttt tggatgataa aatcgttgaa cgcctcgttt
     4021 ctggaataag atgaatgtca aaactgttat catgcttatc aaataccgtt agactaacac
     4081 catccacagt aatagaccct tgcttaacta actgattatt aatatgttgg ctacattgaa
     4141 tcgtaataat tttggcattg gctgtttcat ttatttttga aactgttcct agttcatcta
     4201 catgaccgag gacaaaatgt ccaccaaacc taccgttacc actcatggca cgctctaaat
     4261 ttacttctga ttgtcgctta acatctgcta aataggtttt attttcagtg cctttaatta
     4321 cttgaacagt aaaagatgtc tgattaaaat caatcactgt taaacatgca ccattaacac
     4381 tgatggaatc accaatatgc atatctgccg taatcttatg tgcttcaatt tcaatcgtcc
     4441 tgactgattg acgaatttga acacttttaa cgacacctat ttcttcaacg atgccagtaa
     4501 acatgcatca tcacttcttt cgtaaagtta atttaacatt ttgatttaat aactcggaat
     4561 gaacaatttc aaattggttc gcatctggta tctcaatcac atcatttgtt tgataaaatt
     4621 gataatttcc agatccgcca attaatttcg gggcataata gagaataaat tcatctatat
     4681 aattagattg gagaaattct gaagtagtgg ttggacctgc ctcgactagc aaagttccaa
     4741 ctcctctttt atataaattg tgaagaattg ttgttaaatc acaagactcc aagaaaataa
     4801 tttcaatatg tgtttgcttg gttgttaaat ttggattttc agtatatatc caaattggtg
     4861 ttgattcatc ttgataaatt tgctgattaa aatgaatatt cccagactta gacaatatta
     4921 cttttatagg gttttttcca tcttgaatac gtgtagtata ttgtggatca tctaattcaa
     4981 ctgtacgtct tccagttaac actgcgtcgt gtcgatgtct taacttatag acatcttgtt
     5041 taacctcttt gttagtaatc cattgacttt gtccattatc attcgcttgt ttaccatcta
     5101 aacttgcaga tactttcact gtaatttgtg gcagttgctt tgcttttgct ttaaaaaagt
     5161 cttggtataa ttgtgatgca cgttcatcat caacgcattc aacctcaata ccgtgagccc
     5221 gtaacgtctc atcaccatgt gtgtctaacg aattgtcttt tgttgcgtaa actactttag
     5281 ttatcttaca atcaataatt ttgttaacac agggtggtgt tgaaccaaaa tgactacatg
     5341 gctctaacgt aatataaatc gtcgcacctt cagcattttg ttgtgccata tcaagtgctt
     5401 gaacctccgc atgcttgtca ccttttctca agtgtgcacc aataccaaca atcctacctt
     5461 ctttaactac aacagcgcca acgggtggat taacacctgt ttgaccttgt accatatttg
     5521 caagttgaat cgcataatcc ataaattgac tcaaatgatc acctctataa acaaaaatcc
     5581 tcacatcatg aattaagatg caaggagaaa aatttatcgt taaataagcc tatttgtaca
     5641 catttttaca aatacgctac attatctttg tcgataatta acattctttc tcccatccag
     5701 actttaactg tcggctctag aatctcacta gatcagccac taatatgaaa catattagca
     5761 ggtcgcaggc tttatttact gccggttggg aatttcaccc tgccccgaaa gaattatata
     5821 tgaaattgtt atagattatt tgagtacgta gtatgtcaac tacatttaaa atgatactat
     5881 atgttttctg aaaaaacaat taatgacggt tttaatttaa tataatctga gtactatagg
     5941 catctcattg atatgattct tactaacaga cattaaaatc aaaccttcaa ttcgtctcta
     6001 tagagcgttc tctttattat cttctagtta caaattattg attgtcactg cgctgttgtt
     6061 gctcattcga ttctaaagca tcatataatt gagatactgt atgcgcaact tgttctacta
     6121 tcatttttac accatttcgt agtttattaa caccgtttgt catttgacct atcgcaatca
     6181 tatttgttaa tgttccaaac cttggactaa taacttgatt ggtttccggt atgatttgta
     6241 tgcctcccat tgagtgtgct tgtacaattt gtctattttc aagattttta attaattgat
     6301 catcttgatc caattcattt aaatgacttt ttgcacctgt cgcgttaatg acaacattat
     6361 atatgtctac tgattcttgg tttttgtatg aaaaataata caacttgcca tcatgtttca
     6421 catcttctaa atcttttttc aaaattaaag acttattttc tattaattca ataattagtt
     6481 cagcagttct tggaggcatt ggatttgaat ttaattgaat catctttgag tatttttgat
     6541 taaattgatg ttgatcttca atacttaagc tattccatat ccaatttaaa ttctctttca
     6601 aatgttcaat catactttgg aaaatgccca tttctgttgg acgcgctaaa tcatacttca
     6661 aatctgcaat atgatttcct gtacgtctat gtactaattt tttaaaatca atgtcatatt
     6721 cagcacattc ttttaaaaat aaagaaacta aagtatcaag cggtgcattg ccgaaatgat
     6781 gttttttaat gtcatttaat ttgtctttag ttaagtactt gaatgtcacg tctatcattg
     6841 tacctcttac acttggtaaa tgagcagaac gactcgtcat agtaattggt aatttcggat
     6901 gatgagcagc aacataacgg acaacatcta aactggcaag gcctgtacca ataatcgcaa
     6961 tatcgtccag ttcatttact tcgtctaacg tattatatgt tggataaggc gtagcgatat
     7021 atcctttttt accctttaag ttatatggat catggtaggc aaatgtacca catgttaaaa
     7081 atacataatc gtacgcttgc catgattgtc ctgaatttgt agtacatatg taataagtta
     7141 aattcgtttc atcgatatta gaatttgtat aaatctcttg aactttatta taattagttg
     7201 atatatttgg atattttttc gtgaacatag ataaataaga tttcatataa tgtccgaata
     7261 caaatctcgg taaatatgca ggttcatcaa aattaaaatc agtttgttgt ttataccact
     7321 tccaaaattc agtctcatca tctaaattta aactcatctt tttcgaaggc atattaatta
     7381 gcagctcaga actatcattt tgaaatggta cgccctgtcc catatttact ttatcatcgt
     7441 ataaatctat atctaattga ttaaacttcg ggtgcttaac taactctctc aatacactta
     7501 caccagcagt tcccatgcct attattgcta cacgcatata tcatccatcc ttttgtaatt
     7561 caaaatatta tatttaaact attacctata attatagcaa tttggtattt ccaataaaat
     7621 ttattaaggt aagctattat ttcactttca caaccattaa accatttaaa acttttcatt
     7681 taatatcaac ctcagtgttt gtgttaaaat atttttaccg aggtgaatta aattgaaatt
     7741 tatagcaaag atattaatct cattagtaat tctatttatg atttttagtc gtaaaaacaa
     7801 agcatcttaa tcaataccct tgattacaaa ataaattcaa ctaaggtgat tggccataca
     7861 ctcaagatat ggcaaatcac ctttttcatt acgtaaattc aaccatcctt tagcaaaatt
     7921 ttcaccatac attttcacaa gtaataattt ttaacaatgc tattagcatc acagtgacaa
     7981 atgactaacg aaacattaaa gcaatcatac atagacattc atctatatag atgataatct
     8041 atttaacgtc taggaggtat gttatgacgt ataaagaact agcaacatat ttaaaagttt
     8101 tgtcagattc aagcagatta gaaatactag atttactttc ttgtggagag ttatgcgctt
     8161 gtgatttgtt agaacatttt caattctctc aacctacact tagctatcat atgaaagcat
     8221 tagtaaaaac caacttagtt acgacacgaa aaatcggaaa taaacattta tatcagctta
     8281 atcataatat ttttgagtcc gtaattaata acttgtcaaa ggttcatacc tctaaccaac
     8341 gatgtatttg tcataacctt aagactggtg aatgctaatg atgacaactt tagcgacact
     8401 catttttcta gtaactttat tatttgtatt atggcaacct aaaggcctag atattggatt
     8461 tactgcatta gcaggtgcaa ttgttgcaat gattactggt gttgtaagtt tgactgatgt
     8521 ttttgaagta acaggtatag tctggaatgc cactttaact tttgtctcag tcattcttat
     8581 ttcattaata ttagataaaa ttggattttt tgaatggtca gctatccata tgcttcatgc
     8641 ttcaaaaggc aatggtttaa aaatgttcgt ttatatcata ttattgggtg ccgtggttgc
     8701 tgcatttttc gcaaatgatg gctcagcgtt aatcttaacg ccaattgtat tagcaatggt
     8761 aaaaaatata ggttttagta agcgggcaat attccctttt attattgcga gtggttttat
     8821 agctgataca acttctttac ctttaatcgt gagcaatttg gtcaatatca tttctgcaga
     8881 ttactttaac attagtttct ctcagtatct cagtagaatg attatcccta atttattctc
     8941 attattaggc agccttctag ttttgtggtt atattttaga aaagcgattc ctaaatcatt
     9001 tgatgcaaat cacataaaaa aacctaaaga tgccattaat gatttaaagc tatttaaaat
     9061 ttcatggatt gttctagtta tattactttt cggctatcta atcagtgaat ttactaaaat
     9121 tccggtatca attttcactg ggatcatagc ttttatattt ctaatgttgg ctcgtaaatc
     9181 aaatgctgta aatattaagc aagtcattaa gggcgcacct tggaatatag tattattttc
     9241 aattggtatg tatatcgtcg tattcggctt aagaaatgct ggcattactt taatattggc
     9301 taaaatatta gaatatattt ccaattacgg tctatttagc accattttgg gaatgggctt
     9361 catttcagcg tttttatcat caataatgaa taatatgcct acagttttaa tagatgcgat
     9421 tgctattggt caatcaaatg tccatggcat gttaaaagaa ggcctaattt atgcgaatgt
     9481 tatcggttct gatttaggtc caaaaattac accgataggc tctttagcta cattactgtg
     9541 gttacatgtc ttaacacaaa aagatgttaa gatttcttgg ggcacatact ttaaaactgg
     9601 tatcaccatt acaattccag tactatttat cacactttta ggattatatc taacacttat
     9661 catattttaa gaaattagga gattgttatg actaaaaaaa caatttattt tatatgtaca
     9721 ggcaactcat gtcgaagtca aatggctgaa ggttgggcta aacaaatctt agcgaaagat
     9781 tgggatgtat attctgcggg tatcgaaaca cacggtgtta atcccaaagc gatagaagct
     9841 atgaaagaag taggcattga tatatcaaat catacatcag atttaatcga taataatatt
     9901 attaaaaatt caaatttagt tgttacatta tgtagtgatg cagacgtaaa ttgccctact
     9961 ttaccaacaa atgttaagaa ggaacattgg ggatttgatg atcctgcagg caaaccatgg
    10021 tcagagttcc aacgtgtgag agatgaaatt aaagtcgcaa ttgaaaattt taaatcacga
    10081 tgagagtggg acagaaatga taaaaaaaca cttatgattt attatgtagt ggctctttat
    10141 cattagctat aactaatgtg tacttaaaaa taggaataca tgagtaaaac tcatgcataa
    10201 gaaatactaa tttctataga agaagtaact cttcatcgat gtcctacccc aacttgcatt
    10261 gcctgtagaa attggtgttc caattcctct atgttagggt cccgccaact tgcattgttt
    10321 gtatacctac tttttgtcaa cttctatgtt gggtcccact tgcattggcg gaattatcaa
    10381 tcaatatctt tctttaatag gcaatgtgtc aagctaaaac tgaaatttct tcaaaaaaat
    10441 taaaaaaagt tgttagacag aaattgaaca gaataacagt ggatttttta agtttaaaac
    10501 aaaataaaag gaaagctttg agaagctctc cgaaataaat ttacaaaaaa atacaattta
    10561 aatgtcttct cctgaacgcg ctcactgtga aacattcgct tgtcctacca ttaaaaagag
    10621 ttatgttttt aacggctcac gcccaaacat aactctttat taatggtcac aagggggaaa
    10681 cactcaatac cgtacctatt tcttattgac cattattctt tttttggcaa aaaaatcaaa
    10741 gcaattatcg ttaaaattat cgtcagaata gcgatataaa ctggcgcatt tatgttttgt
    10801 acgtaaaagt aacctgcaat aatgggggca attaacgtac ctaaagatgt aaaggttgag
    10861 ttcatagaac ctgctaaacc ttgcttatct tttgcgattt ttgataaata tacagtaatt
    10921 gctggccgta taatatcaaa gcctataaaa ataacacaac taattaaaac aagtgctatg
    10981 acagaattta agagtaacaa aatacataat accattattg aataaataga gctaatgata
    11041 ataatagaaa actcatgtaa atgccttgag attttaggat aaaccaaata ttgtgttagc
    11101 gcccccaaca atgaaccacc gataatagca agggcaatat gaaacgaagt aaagtctgcc
    11161 ttatctacga gatataacgg atacaattct tcaatcgcag ctaatccgaa agctaataaa
    11221 agtatcacca tcgctggtaa taaataaagt ttcaaatatt taaatgataa agttgctaat
    11281 ttattttctt ttgatgccaa tgtttgaaca tgtggtattt tcaaatttaa attaattatt
    11341 aacataatga tacctatagc catagctata aaatacggta gtctaagatg aaatgtagca
    11401 aacaatgcgc ctataccagg gcctatgata aagcctaatg acgtgattgc tgaaaacgtg
    11461 ccgaaatttt tatcgcgatt agcttcatca gatatgtcac caataatacc aataacggaa
    11521 gtttggatta acgccgcact tataccaccg agtatcctcg aagacaaaag tgtatagaac
    11581 cccataccaa ttccaaataa aaattcagaa acgatataaa gtaacaagcc aatagataaa
    11641 aagtgctttt tagcgtatct atcagaaaaa aagccaacta taggcgaaaa aatcatttga
    11701 aaaagagaaa atacagcaat aagtatccca aaagcatcac catctatatt taaatcttta
    11761 atgattaatg gcaagctagg aacaactaaa ctaatagctg taaatactaa gaaaatatta
    11821 atatatagtg gaactattaa acttttttta atcattgtaa ctcctttggg gatacatgat
    11881 taaagttaat atttcaatta taattcacga aaaatgttta cataattgag gattcttaaa
    11941 catatatccc agctaatttt ttattttgta cttttaatcg atttatgatg actgacataa
    12001 atattcctcc tttttaatgc tcacattata caatatctat ttttaaatga aaatagtcat
    12061 tttatctctt caaaataagg tctaaatgaa ccattaaatt cattctcttc ctgttatttc
    12121 ctttaatatc tcttcacttg acttatagtt aaatatcata agaggacgtg cattaatttg
    12181 ttcaacatct ttcgcaaaat catattgttc cattaaagga acatcaaaca aaacaggctc
    12241 attatattat cctaaaatag agatataacc tcctccaata cctgattcat gtattgattg
    12301 aaattcctta tcagtttggc caaagatcat tttataacca tcagttgata aattacctaa
    12361 agatacgcgt aatcccaatt ggtcacgtac attcccttta atgacatctg catcaggacg
    12421 ttgcgctgtt aaaaacataa atatacctgc atgatgacct ttcataataa tatttacaag
    12481 ataatcattc atttcctgta attctttttt atctaatgtt gatgtaactg ctgtaaactc
    12541 atcaaaaata acgaagtatg caggcatatc aaaacttcta aaatcatgtc caattcgata
    12601 atcttcgctt tccgtcatta atcggaaacg attttccatt tcttcattcg ctaatctcaa
    12661 ttgtttaaat atctgacctt tcatatctgc aactttatca gaactaatca cacgtttaaa
    12721 tcaagtagga gaataatcat tacttgatta ttcgtcccct cacaccaccg agcgtatggt
    12781 tctgtgcgca catatttccc cttttttcgt tccactactt atctctccat aagttgccaa
    12841 ctagttcgtt gttttctgca tgatgtaaat ctataacctc cattctttac tttgtatgaa
    12901 tattgttccg tccttcggta cattttccct actatgacgt ctgctgactt ctcattattc
    12961 gttgttacta cggtatgtgc accgctaatg agacctccct gggtaaggcg caaccacttt
    13021 ccactcatct catcgcatca tttaccatat aaaattcggg tagtattgga cttcatcttg
    13081 tttagcagac tcatccgttt tatatggcct tattatgatg tttctgttcg tcaatgcgag
    13141 tgtttgcgtc cgacttcctt cagattccac ttcacaatgg acacccttgt ctttcgctaa
    13201 cagttcctac taccaagcct gtaacggact ttcaccgtca agttgttgcc catgccaggc
    13261 gcactaaaaa gacgctttct atttattgcg atagaaagcg tctttttata cttgagcaag
    13321 tcatatcata acttaactct aataaattac ttattcaaat gtttactgtc atctttatac
    13381 acaaagtatt tgaagtattt tccttcagtc ttcatgttct tataaaagtc agcgataatt
    13441 gttgcattac tttctgccca cttaatatca gtagcatatt gatgttctcc tggatttttt
    13501 ggattccatc tcatactata caatgtattt tgatctgtgc ttgataagaa gtgcttatga
    13561 atgaaatcag caccgcctga aatagctttt tcaggtgtat cccaaccatg ctttttagca
    13621 tattctgcac ctgttttaat tgggtcttta tcaagggctc ctactccata gaaattgtag
    13681 tattttttgc catcaatttc gactccatta gctaattcac ttttaactgc gccagtttct
    13741 aataatgcat gtgaaattaa ataaacttcg ttaacgtgct tatctttagc agcttttaag
    13801 aaatcatccg tatgtttcaa taacgttggt ctatctacta acatacgttt aattctattt
    13861 ttatcaatcc cttgatactt tgataaatct aaaaattgat atttttgctt ttcattatcg
    13921 ataaaagtac cgctatccat tgcactttta atttcagttg cagatgcatc tcgccatgca
    13981 tcattctttt tatttgatac ctgttgactc gtataattat ttatttgttt ctttgctgca
    14041 tcgtttaatg taacatttaa cttttcaatc ttaatgtcgg atttaacatg tttgaaaaat
    14101 atctgatcgg atatcattga gaaaaataaa aatgagacaa cagcaaatat gacaacaagt
    14161 cctattattc caaaaataga acctttcttg tgtttattca tatccacacc tcttaggtca
    14221 ttgttgttat acattcagtt tgactacgat aataaagttt aacattatta aaaccgttta
    14281 acaattttat ctatgcattg ttacatattc ataaataaac agtaatgtaa atgaaacgtt
    14341 ttaaacgatt tatcaacatt actttacgtt gatatacgaa tcataaatgt tttatctttt
    14401 tgtataacct ttgaaaacct ttatatcaat aatcttatta ttcacgtatt aaaaaacaaa
    14461 aaattctctt gttcgtttac ttagtttctt ttttataatc catcataata aaacttgctg
    14521 catttgatct atttttataa tagtactgat ttaaatcaat cgtaccttca atttgaccat
    14581 cacgatacat catttcatta gtgaaattat ttatcatcac gaaatcagcg cgatctctta
    14641 taacatctaa atcgtcgttt cgtgcaaaaa aatgttctaa atttaaatgt gcgtaatcca
    14701 ttgttacctc ccgattacaa attttgttct atctactatt tagcaaagta ataatacatc
    14761 atatcacatt aaattaatta cttatgtctt atatttaaca cttaatttag cgattacgca
    14821 aatgaatgat ttttctaaat attttattct aactttatcc ggaaatattt gttatacgta
    14881 taacttggag aatgactact tgaaatttaa tgacgtatac aacaaacacc acaaaatcat
    14941 acaccatctt ttaaaaaaat ataatattag ctataattat gatgagtatt atcaactact
    15001 cttgataaaa atgtggcaat tgagtcagat atataaaccc tcaagcaagc aatctttatc
    15061 ctctttttta ttcatgcgac taaactttta ccttatcgat ctattcagac aacaaaaacg
    15121 tttaaatgat atcattttat atgaaaatca ttcaccaata cttactgaac agccaattta
    15181 ttttaatgaa ttcaacttaa atttacaaga tgtttgtgcc ctactaaacc acagggaacg
    15241 acagtggctt atgctttatc ttgaaggcta taagcaatat gaaattgctg atattatgtc
    15301 attatcaact tcaacaatta aattaattaa ggcatcagtt aagcgtaaat gccaacgttt
    15361 ttttaaatag atgcgacgtg tcgtgttgat taaaatgatt aatactcttg gaacgctcaa
    15421 taatatgcat ttcatttttg cgaaccattt tattattaac tgattgaaaa ggagtactat
    15481 atttgcaaga catttctaca aaacacctac tttatatcca aaccgcaact tcgaaccatc
    15541 ttgagacaaa atgtgtcttt ctgtaccatg agtacaatct cgaattccct attactaaag
    15601 ccattcctta ttatgctaaa ttgcatttta catcagcatc aattttaatc gatgcagcaa
    15661 aaagcatact caacattaac aagctggtgc ctatttacct taatccgaaa acgattcttt
    15721 tcccaataaa acaaaagcgt gcaccgatac aaacatatat caatgcacac tatgtaattg
    15781 gtatgacgga aatgggcaat tcaactatgc tccatttcaa aaatggcaaa acattagaag
    15841 tcgatgaacc catgtctctt atttcaaaaa aatgccatga aagtttagca ttgaagcatt
    15901 tcattgaaaa tactaatgac cattaaattt atgttctatc agtttctttg taaaatatga
    15961 tgttgtgatt tttattaaat agatactaac taacattaat aaaatcgccc caatgattgt
    16021 taaaataaca accgttgtcg acaattctac tttaggatta acgaaaaatt gcacaccaga
    16081 tagacttgta attaatccga ataaaaacaa acctaataaa gcaacgtatg caaacatcat
    16141 cactactaat gttacaaaga tgctataact tttagtttct ttactacgaa atacattttc
    16201 tcttaagtac gcattagcaa aggtgattgg cttattaaag ttcacattgt ccttgtcagt
    16261 aatactagac aaccgttgat ctaatgcatg tttttccttt ttgttcaaaa accataattg
    16321 ctttttaacc tttttatcga acgatgcttt attcataatt aaggatttct ctcctttttc
    16381 atattgacgc tattttatac atgattgcca atgaacattg tattttatat attttacaga
    16441 aatacatgca tcaaatctac aaaaattaac tttgcaattt tatttttagt aatttgacac
    16501 tgtataattg acaccattta tattgcaaac aaatgttttt agttaagtgt aatgatgcgc
    16561 ctttaatcat atctaagttt ctcatataat gaaaatgaac ataccaatga aatgctttaa
    16621 tattcatttt atagatgata gaaaggatta aatatgcaga aattcaagga tttgttttat
    16681 gatgatttat cagttgcacg cggaaattat tttctaactt tattatacgc attcttgatt
    16741 actattattc tactaattgg cttcgttgtc agtaatacac acatacttta tggcatgttt
    16801 atagtgctca tcggtatcgt gttattacgg ttattcaaaa ttaatttact ctcatttaaa
    16861 aaattaacaa tgtcacaagt gatttatatc atcggtggtg cattgctaat ttatgggtta
    16921 gatcatcttt atttacattt tcatgacgta cctacaaatg aacaagaatt agatcgagaa
    16981 ttacaacata cgcctttgta tatgtctatt gtcacaattg ctattatccc tgccattgta
    17041 gaagaaatcg tttttcgagg catgataata agagttgtat ttagaaagca tttatttatt
    17101 ggattagttg tgtctagtct agtgtttgca tcattgcatg aatcggatac ttggattggg
    17161 tacttacctt atttatattc tggagtgatt tttggcctaa tatatttaaa aacaaagcga
    17221 ttagaagtcg ttattttaat ccactttata aataacctat cctcattact cattctgata
    17281 tggggataat actagttgat ataatacaca atgattgccc ctcaacatgt aattcacaaa
    17341 acgatatgca atacaaatta atgatatgca agcttttaaa acaataaaaa atcttgtata
    17401 attaacttaa ttttcataaa aattaaacgt caaactttat tttaggagaa ttaatatgtt
    17461 ttcgaggaat aacaatattt ttgttgatga tttgtctgta acaaaggaca attatttaat
    17521 tgcagtttta aaaatgttgg tcattttttt agtaattaat tatggaacag acgtcagtta
    17581 tgaccatgag tatgttgggc tatttattat attactaggt gttgtacttc ttaaagtttt
    17641 aaatatcaat ttattatctt tcaaaaaatt aaaattcact catatgcttt atattatatt
    17701 tgggtttttg ttgatgtatg gattagatta cttatatgat atgttcgcac cgcctacatt
    17761 aaatgaaata ttgctagatg aagagtctga agatgcacct taccacatag ctctgcttag
    17821 tactgctatc attccaccaa ttacagaaga aatcatctgt cgtggattga ttatacgaat
    17881 tttattcaga aatcatcttt tcttaggttt tattgtttca actgtattct tcacgctaat
    17941 acatgaacca gacacgctga ttggttatct tccgtatttt tattcaggtt taatttttgg
    18001 ctatacttac ttaaaaacaa aacgattaga ggtaccgatt ttaatacatt ttatcaataa
    18061 cctcttagcc atgtaacagt aaaatcatta attattttga tatttacatg atgacaccaa
    18121 agcttttaca aagtattaat aggtgccttt ccaaatgtta ttgcatattt acgttctgta
    18181 attatatcaa aacaacaaaa catattaagt ttagctatga aaaaaatcta tgacgataga
    18241 ttttttcata gctatttatt atagttattg agcctatccc agactctcta tactgttata
    18301 ttagcagtca ttgactgaat gataatacgc ttttcaatta taggggcccc aacacagaga
    18361 atttcgaaaa gaaattctac aggcaatgaa atacatatta gtttaaaatt gactccaata
    18421 tgaaaaaccc ccataagcac aatgcctatg agggtttaaa tatatttata tattatagaa
    18481 tagaaagacc tgaagattga atatctttcg caaagccttt aactgtatct actgataatt
    18541 cgttaatatc gcgacctaag tttgtattca cttttttcac aacatctgca gggcatgtaa
    18601 taatatctgc accaatttca tcagcttgaa tcacattgaa taattcgcgg caacttgccc
    18661 ataataattt aacgccgtct ttactatgcg taacttttac agcctctttc attaatggta
    18721 atggatctac gcctgtatct gcaatacgtc ctgcaaatac tgaaacatat gttggcacac
    18781 cttcagttac tgcttcagtt atttctttaa cttgttcaat agtgtaaaca gacgtaacgt
    18841 ttaatctcac attgtcagct gaaagttttt taattaaagg aatcgttgat tcaccttttg
    18901 tatttacaat gggaatttta acaaatacat tttcgccata ttgttttaaa attgctgctt
    18961 ctttttccat agtttctaaa tcgtctgcaa atacttcaaa tgaaattgaa gcatctggaa
    19021 tttcttttac agcttcttca gcaaaagctt tgtaatctgt tacgcccgct ttcgccatta
    19081 aactaggatt tgttgtaaaa ccatccactt gtttgttttt ataagctgct ttcatttctt
    19141 caatatctgc accatccgca aatacttcta catttagttt agccatataa tatagcctcc
    19201 ttgattctta ttaaaatttt aacaacatct gcatgtcttt ttcttacaac catttgtaaa
    19261 aaatgatttt tatttctttg ttatataaaa catttatatc acgcttttat aatatatagc
    19321 taattttttg cctagatttc ttaaaaaaga ctttagcaac attgtgtcaa catggtaatt
    19381 aaactattgt tttatgattg tttatgatac gatatgtaaa tgataaccat ccaggaggtc
    19441 tagcatgtct cgttcaaaaa aatactttta cttatctagc ttaatgatta ttttaagctt
    19501 tttctttaat acaaataacg ttttcctaag tgggcttttt aattctttta ttaaattaat
    19561 acttttctgc agtgttatta actcaattat actaatattg tctataattt ttgcagatcg
    19621 ttcaattaaa tcactaaagc ctgatgcgga ttggattaga attgcgagta aaagtttgcc
    19681 ttggattatt ctaatcgtta ttttagtaca tatcttttcg attgttcaca cattcggttt
    19741 tatttaaaaa agataaaatg tcaatgtagc cttaatacaa aacaatacaa tgcatcatgc
    19801 tataatgagt aaatcaattt gatgatgttg ttgcgtttaa aaaatattag attttcgaaa
    19861 tcataactat gcatctaatc gctatagtta tacaacaaga tataacatat aatgaggttt
    19921 gataatgcat cgacaatttt tgtcgtcgcg ttgccaaaac ctctttttta aattcaaact
    19981 acttcttttc gaggtgaacc aaatgcaata tgtatatatt tttatcggtg gtgctttagg
    20041 cgctttatta cgttacctca tttcttttct gaatactgac ggaggttttc caatcggaac
    20101 actgatagcc aatttgactg gtgcctttgt aatgggattg ctaacagcct taacaattgc
    20161 atttttttca aaccatccga ccctaaaaaa agctattacg actggttttc ttggtgcatt
    20221 aacgactttt tcaacatttc aattagaatt aatacatatg tttgatcatc aacaatttat
    20281 aactttacta ctatatgcta taacaagtta tgtctttggt attttgttat gttacgtcgg
    20341 tataaaacta ggtggtggtt tatcatgata tcaatcattt tagtcatgat tggcggcggt
    20401 ttgggtgcaa ttgctagaag tgccgttact gattatttta atcataaatt tacttccaag
    20461 ttacctatcg caacattgat agtaaatctt gttggtagtt ttttaattgg attaactata
    20521 ggcttatcaa tttcaatctc atggttccct gcgttctttg ttaccggttt tttaggtggc
    20581 ttaacaactt tctcaacgtt agccaaggaa cttacactaa tgatgatgcc aaaatttaat
    20641 attaaccttt ttctcaatta ttcactttta caattcatca ttggatttat agcttgttat
    20701 attggctatc atatttaaaa ataaaatgct tcattcagca aataggcaaa ttacgacacc
    20761 ttcctgaacg aagcattttt ttattttcat gcaaattttt tagcaccata aaatgcctac
    20821 caaatttcaa taatctttgt taccgtttaa ataatgtgaa tgtcaataaa ttctccaaac
    20881 tagtcgaaaa taaaacaggc tgggacataa atccctaaaa aaacagcagt aagataattt
    20941 tcaattagaa aatatcttac tgctgttctc tatttataca atacttcgta ttgaatggct
    21001 tcgctttcct agggtgccgt ctcagcctcg gtcttcgact ggcactgctc cctcaggagt
    21061 ctcgccatta atactacgta ttaacatgta attttacttt tacatacttt aaaaaaa
//
LOCUS       DAPSKH010000049        21110 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPSKH010000049 DAPSKH010000000
VERSION     DAPSKH010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21110)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21110)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21110
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.049"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            134..598
                     /locus_tag="RPH49_001940"
     CDS             134..598
                     /locus_tag="RPH49_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125079.1"
                     /translation="MDRQSFTDLIQTKFKMVRIEAGYTQDTMAQTIGLSKKTLVQIEK
                     ERVLPNWTTCISICALFRDSEVLNSTFGCDPLEIVQTISRNHCAYPNHAPTSDIYWNN
                     IETRNGYILQSNKVSNIYRVLNPDNQPIFGTSKMREAETYFNRNAKEELVHI"
     gene            777..1901
                     /locus_tag="RPH49_001941"
     CDS             777..1901
                     /locus_tag="RPH49_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDY5125080.1"
                     /translation="MNALFIIIFMIVVGAIIGGITNVIAIRMLFHPFKPYYIFKFRVP
                     FTPGLIPKRREEIATKIGQVIEEHLLTETLINEKLKSEQSQQAIESMIQQQLQKLTKD
                     QLSIKQITSQLDIDLEQVLQTNGNQYIESQLNNYYTKHQNQTIASLLPNQLVTFLDQH
                     VDNATDLLCDRARNYLSSAKGTQDINDMLDTFFNEKGKLIGMLQMFMTKESIADRIQQ
                     ELIRLTSHPKARTIVTSLITNEYQTFKDKPLNELLDAAQFNEIAENLSVYVTTYASKQ
                     ANKPVVTLMPQFVDYLEGQLSSKLANLIIEQLSIHLSTIMKKVDLRGLIEEQINTFDL
                     DYIEKLIIEIANKELKLIMSLGFILGGIIGFFQGLVAIFV"
     gene            1970..2314
                     /locus_tag="RPH49_001942"
     CDS             1970..2314
                     /locus_tag="RPH49_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002498160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HDY5125081.1"
                     /translation="MAVNLYDYANQLEQALRESEEYKAIKEAFANVKANEESKKLFDE
                     FRETQINFQQKQMQGEEIAEEDLQKAQEQAQAIEKDENISALMNAEQKMSQVFQEINQ
                     IIVKPLDEIYAD"
     gene            3086..4282
                     /locus_tag="RPH49_001943"
     CDS             3086..4282
                     /locus_tag="RPH49_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDY5125082.1"
                     /translation="MVKFIHCSDLHLDSPFKSKSHISPKIFEDVQKSAYESFKNIVDI
                     ALQQDVDFVIIAGDLFDSENRTLRAEIFLKQQFERLQNEQIFVYVCHGNHDPLSSKIS
                     SNWPDNVSVFSNKVETYEAITKSGETIYIHGFSYENRASYENKIDEYPSSQGQKGIHI
                     GVLHGTYSKSSVNERYTEFILEDLNSKLYHYWALGHIHERQQLSDMPVINYSGNIQGR
                     HFNEQGEKGCLLIEGDHLKLKTKFYPTQYIRFEEATIETDKTSKQGLYEVIQNFKEQV
                     REEGKAFYRLTLVINSETLISPQDLLQVEEMITDYEENENQFVYIDELKIQYAQNDES
                     PLVNEFSAELLVDQTVFDKAMSDLYLNPRASKFLDDYGTFDHTALVNRAEEILKAEMR
                     GEQNDN"
     gene            4272..7208
                     /locus_tag="RPH49_001944"
     CDS             4272..7208
                     /locus_tag="RPH49_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDY5125083.1"
                     /translation="MIIKSLEIYGYGQFVQRKIEFNKNFTEIFGENEAGKSTIQAFIH
                     SILFGFPTKKSKEPRLEPRLGNQYGGKLVLILDDGLEIEVERIKGSAQGDVKVYLPNG
                     AVRDDAWLQKKLNYISKKTYQGIFSFDVLGLQDIHRNLNEKQLQDYLLQAGALGSTEF
                     TSMREVINRKKDELYKKSGKNPIINQQIEQLKQLESQIREEEAKLETYHRLVDDRDKS
                     SRRLENLKHNLNQLSKMHEEKQKEVALHDHSQEWKSLEQQLNIEPITFPEKGVDRYEK
                     ARAHKQSLERDIGLRNERLAQLKEEATQLEPVKQSDIDAFISLNQQENEIKNKEFELT
                     AIEKDIANKQRDKDELQANIGWSETHHDVDSSEAMKSYVSEQIKNKQEQAAYIKQLER
                     SLEENKIEDNAVHSELDSVEKKIVPEETFEKKKEYSQQVIELNEKENLYSKLKERFEI
                     EQQEKQKRQKLLRTTFILLTLVGIGLTAFSFISNNMLFGIIFAVLTLVFVIGIIMSKS
                     KEVDYSEAITDEIEEIKAQLAILDENYDLDFDLDEQYRIRDHWQQALKNKDILEEKRQ
                     YIEGRLNDAKGRHDELQSTVENVKDELYLSSKISNDLIVDSISTMANIKALDQHISDL
                     NQQRQQLVQELDTFYNHAEAVTKLQFVYFNKLSLFHDVQQWLKSAEDTNEKWRINAEN
                     TKLVTNELNHLNAQLEENNKEITALFDFINVGTEEDFYQHHEDYQTYTSNLSRFNDLT
                     KYLENQNYSYELSSSLSEKTTAQLEEEDHLLATQVDEYNEQYLEMQAQVSDLSAQINH
                     METDTTLANLRHEYHSLKNQLNDIAKDWASLSYLQSLVDEHIKQIKDKRLPQVINEAV
                     EILKHLTDGRYTMINYNEDSITVKHVNGQLYDPVELSQSTKELLYVALRISLIKVLRP
                     YYPFPLIVDDAFVHFDKKRTEKMLNYLRSLSEHYQVLYFTCVKDNIVPSKEVITLNKI
                     EEGGKR"
     gene            7205..8146
                     /gene="yhaM"
                     /locus_tag="RPH49_001945"
     CDS             7205..8146
                     /gene="yhaM"
                     /locus_tag="RPH49_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM"
                     /protein_id="HDY5125084.1"
                     /translation="MRNIENLNPGDSVDHFFLVHKATQGVTAQGKDYMTLHLQDKSGE
                     IEAKFWTATKNDMATIKPEEIVHVKGDIINYRGNKQMKVNQIRLATTEDQLKTEQFVD
                     GAPLSPAEIQEEISHYLLDIENANLQRITRHLLKKYQERFYTYPAASSHHHNFASGLS
                     YHVLTMLRIAKSICDIYPLLNKSLLYSGIILHDIGKVRELSGPVATSYTVEGNLLGHI
                     SIASDEVVEAARELNIEGEEIMLLRHMILSHHGKLEYGSPKLPYLKEAEILCYIDNID
                     ARMNMFEKAYKKTDKGQFTDKIFGLENRRFYNPESLD"
     gene            complement(8267..9229)
                     /locus_tag="RPH49_001946"
     CDS             complement(8267..9229)
                     /locus_tag="RPH49_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HDY5125085.1"
                     /translation="MKMINKLIVPVTASALLLGACGASATDSKENTLISSKAGDVTVA
                     DTMKKIGKDQIANASFTEMLNKILADKYKNKVNDKKIDEQIEKMQKQYGGKDKFEKAL
                     QQQGLTADKYKENLRTAAYHKELLSDKIKISDSEIKEDSKKASHILIKVKSKKSDKEG
                     LDDKEAKQKAEEIQKEVSKDPSKFGEIAKKESMDTGSAKKDGELGYVLKGQTDKDFEK
                     ALFKLKDGEVSDVVKSSFGYHIIKADKPTDFNSEKQSLKEKLVDQKVQKNPKLLTDAY
                     KDLLKEYDVDFKDRDIKSVVEDKILNPEKLKQGGAQGGQSGMSQ"
     gene            complement(9434..9991)
                     /locus_tag="RPH49_001947"
     CDS             complement(9434..9991)
                     /locus_tag="RPH49_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3267 domain-containing protein"
                     /protein_id="HDY5125086.1"
                     /translation="MFLCKRQIDINARFGLPRIAFMSAVATIIMFLVSYEVMYFLSNT
                     PLSDRHFLIFLLLVFMTYPLHKSIHLLFFLPYRKSFKVHKLTKRKWLIFYNTYVNQPV
                     HKFYFCINLILPLIILSAMFVYLTISFPQYGHYFMFLLALNFGISITDLLYLKIIIFS
                     NYGQYIEEHSTGINILKKIKNPYHL"
     gene            complement(10724..11089)
                     /locus_tag="RPH49_001948"
     CDS             complement(10724..11089)
                     /locus_tag="RPH49_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDY5125087.1"
                     /translation="MKASRILFGIGVGVAAGFVVALQGRDDKSVKNNTIDRTAPTGSK
                     SELQREFETIKQSFNDILNYGVQIKNESAEFGSSIGGEIKSLLGNFKSDINPNIERLQ
                     SHIENLQNRGEDIGNEISK"
     gene            complement(11231..11653)
                     /locus_tag="RPH49_001949"
     CDS             complement(11231..11653)
                     /locus_tag="RPH49_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDY5125088.1"
                     /translation="MSETIFGKILTGEIPSFKVYEDDYVYAFLDISQVTKGHTLLIPK
                     KASANIFETDEETMKHIGAALPKVANAIKRAFNPDGLNIIQNNGEFADQSVFHIHFHL
                     IPRYENDIDGFGYKWETHEDILDNDAKQQIAEQIQAQF"
     gene            11787..12527
                     /locus_tag="RPH49_001950"
     CDS             11787..12527
                     /locus_tag="RPH49_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125089.1"
                     /translation="MTVKVEQLTGGYGKRPVIKDINFELNKGEIVGLIGLNGAGKSTT
                     IKHMLGLLTPMEGSLSISDININDDIEAYRRKLSYIPESPVIYEELTLEEHIEMTAMA
                     YDIDRDEAMNRAMPLLKTFRLENELKVFPSHFSKGMKQKVMIICAFIVNPELYIIDEP
                     FLGLDPLGIQSMLDLMVEKKNEGRTVLMSTHILATAERYCDRFIILDEGEVVAFGDLE
                     ALRQQTGLHNQTLDDIYIHVTQGGDVHA"
     gene            12520..13743
                     /locus_tag="RPH49_001951"
     CDS             12520..13743
                     /locus_tag="RPH49_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125090.1"
                     /translation="MRNQATTLFNKRLHALRKEKNYYNKFIFNGHFMVFLLILLGAFI
                     FGYGEWLKHIPTNINFALIAAVIVALTSIFPMRPLLKEADKIFLLPFEKHMSQFMRHA
                     ILYSYFARILIQLIIVIVMFPLFYNINQHNVAFYICFGVSALIFPYVGLRIRWQWYQS
                     GLKTWQVNLISFIIFALTYYLLLAPKWYIAFVMVALPVLIEFLVKKYKPGFLYPWEKM
                     IAIEHRHHMNYYKFVNMFTDVKHLKESAVRRSYLDILLPVPKGSKFNSNAMYLFLFIR
                     SFIRGRDAFNIIFRLVIIAVLLMLWLSYPLVTAIIGCLFVYIILLQMAQFYSQQAYGL
                     WPQVWPVPEEKVIKGYEQFLYRLMFVICTVFAVAFIIKHMTLFYVVLIFYIVGLLTIR
                     SIIKKLKYQETLLRD"
     gene            complement(13867..14370)
                     /gene="traP"
                     /locus_tag="RPH49_001952"
     CDS             complement(13867..14370)
                     /gene="traP"
                     /locus_tag="RPH49_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein TRAP"
                     /protein_id="HDY5125091.1"
                     /translation="MKKLYTSYGTYGFLNQIKINNPSHHLFQFSTTDSSVIFEETEEN
                     TVLKSPSIYEVIKEIGAFNEDHFYCAIFIPSTEDHVYQLEKKLISVDDNFKNFGGFKS
                     YRLLRPVKGTTYKIYFGFADRQTYEDFKNSDAFKDHFSKEALSHYFGSSGQHSSYFER
                     YLYPIKE"
     gene            14535..14642
                     /locus_tag="RPH49_001953"
                     /pseudo
     CDS             14535..14642
                     /locus_tag="RPH49_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500462.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14632..15669
                     /gene="hemE"
                     /locus_tag="RPH49_001954"
     CDS             14632..15669
                     /gene="hemE"
                     /locus_tag="RPH49_001954"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDY5125092.1"
                     /translation="MVHNKNNTILKMIKGEETTHTPVWFMRQAGRSQPEYRKLKEKYS
                     LFDITHQPELCAYVTHLPVDNYHTDAAILYKDIMTPLKPIGVDVEIKSGIGPVIHNPI
                     KTIQDVEKLSQIDPERDVPYVLDTIKLLTEEKLNVPLIGFTGAPFTLASYMIEGGPSK
                     NYNFTKAMMYRDEATWFALMNHLVDVSVKYVTAQVEAGAELIQIFDSWVGALNVEDYR
                     RYIKPHMIRLISEVKEKHDVPVILFGVGASHLINEWNDLPIDVLGLDWRTSINQAQQL
                     GVTKTLQGNLDPSILLAPWNVIEERLKSILDQGMENGKHIFNLGHGVFPEVQPETLRK
                     VSEFVHTYTQR"
     gene            15727..16650
                     /gene="hemH"
                     /locus_tag="RPH49_001955"
     CDS             15727..16650
                     /gene="hemH"
                     /locus_tag="RPH49_001955"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDY5125093.1"
                     /translation="MTKKMGLLVMAYGTPYKESDIEPYYTDIRHGKRPSEEELQDLKD
                     RYEFIGGLSPLAGTTDDQADALVSALNKAYADVEFKLYLGLKHISPFIEDAVEQMHND
                     GITEAITVVLAPHYSSFSVGSYDKRADEEAAKYGIQLTHVKHYYEQPKFIEYWTNKVN
                     ETLAQIPEEEHKDTVLVVSAHSLPKGLIEKNNDPYPQELEHTALLIKEQSNIEHIAIG
                     WQSEGNTGTPWLGPDVQDLTRDLYEKHQYKNFIYTPVGFVCEHLEVLYDNDYECKVVC
                     DDIGANYYRPKMPNTHPLFIGAIVDEIKSIF"
     gene            16674..18074
                     /locus_tag="RPH49_001956"
     CDS             16674..18074
                     /locus_tag="RPH49_001956"
                     /EC_number="1.3.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoporphyrinogen oxidase"
                     /protein_id="HDY5125094.1"
                     /translation="MTKSVAIIGAGITGLSSAYFLKQQDPNIDVTIFEASNRPGGKIQ
                     SYRKDGYMIELGPESYLGRKTIMTELAKDIGLEQDIVTNTTGQSYIFAKNKLYPIPGG
                     SIMGIPTDIKPFVTTKLISPLGKLRAGLDLLKKPTQMQNGDISVGAFFRARLGNEVLE
                     NLIEPLMGGIYGTDIDKLSLMSTFPNFKEKEEAFGSLIKGMKDEKNKRLKQRQLYPGA
                     PKGQFKQFKHGLSSFIEALEQDVKNKGVTIRYNTSVDDIITSQKQYKIVYSNQQEEVF
                     DGILVTTPHQVFLNWFGQDPAFDYFKTMDSTTVATVVLAFDEKDIENTYDGTGFVIAR
                     TSDTDITACTWTSKKWPFTTPEGKVLIRAYVGKPGDTVVDDHTDNELVSIVRRDLSQM
                     MTFKGDPEFTIVNRLPKSMPQYHVGHIQQIRQIQAHIKQTYPRLRVTGASFEAVGLPD
                     CITQGKVAAEEVIAEL"
     gene            18397..18951
                     /locus_tag="RPH49_001957"
     CDS             18397..18951
                     /locus_tag="RPH49_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase family protein"
                     /protein_id="HDY5125095.1"
                     /translation="MTDVIIVHSMHGNSRNHWYQWLEHNLTLEGYDVTLFNFESPEAK
                     TVDQWIEAMTKQINVRKKDTYFVTHGLGSITALKYIEMIDQPIEGFFSIAGFKEDAEN
                     IDLDIDLSNVTIDYDNIKKKVDNFYGLSSKNDKYVSYKETQRLMNALEGNLRIVEDGG
                     HFLEEDGFETFTALQDRMQDYMTR"
     gene            19344..19417
                     /locus_tag="RPH49_001958"
     tRNA            19344..19417
                     /locus_tag="RPH49_001958"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19378..19380,aa:Met,seq:cat)
     gene            19439..19514
                     /locus_tag="RPH49_001959"
     tRNA            19439..19514
                     /locus_tag="RPH49_001959"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19472..19474,aa:Asp,seq:gtc)
     gene            19531..19603
                     /locus_tag="RPH49_001960"
     tRNA            19531..19603
                     /locus_tag="RPH49_001960"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19564..19566,aa:Phe,seq:gaa)
     gene            19617..19692
                     /locus_tag="RPH49_001961"
     tRNA            19617..19692
                     /locus_tag="RPH49_001961"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19650..19652,aa:His,seq:gtg)
     gene            19708..19781
                     /locus_tag="RPH49_001962"
     tRNA            19708..19781
                     /locus_tag="RPH49_001962"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19740..19742,aa:Gly,seq:tcc)
     gene            19796..19870
                     /locus_tag="RPH49_001963"
     tRNA            19796..19870
                     /locus_tag="RPH49_001963"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19828..19830,aa:Asn,seq:gtt)
     gene            19872..19943
                     /locus_tag="RPH49_001964"
     tRNA            19872..19943
                     /locus_tag="RPH49_001964"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19905..19907,aa:Glu,seq:ttc)
     gene            19998..20086
                     /locus_tag="RPH49_001965"
     tRNA            19998..20086
                     /locus_tag="RPH49_001965"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:20033..20035,aa:Ser,seq:gga)
     gene            20299..21081
                     /gene="seo"
                     /locus_tag="RPH49_001966"
     CDS             20299..21081
                     /gene="seo"
                     /locus_tag="RPH49_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type O"
                     /protein_id="HDY5125096.1"
                     /translation="MKNSKVMLNVLLLILNLIAICSVNNAYANEEDPKIESLCKKSSV
                     DPIALHNINDDYINNRFTTVKSIVSTTEKFLDFDLLFKSINWLDGISAEFKDLKVEFS
                     SSAISKEFLGKTVDIYGVYYKAHCHGEHQVDTACTYGGVTPHENNKLSEPKNIGVAVY
                     KDNVNVNTFIVTTDKKKVTAQELDIKVRTKLNNAYKLYDRMTSDVQKGYIKFHSHSEH
                     KESFYYDLFYIKGNLPDQYLQIYNDNKTIDSSDYHIDVYLFT"
BASE COUNT         7591 a         2981 c         3718 g         6820 t
ORIGIN      
        1 atacaaatgt gaaattgact cttttcattt tattaaaaat atattaagat gtaatctgtg
       61 tttcaagaaa tgtgtattat tgcaatttct tgtgtccgga taaaattccc caaacagaaa
      121 ggtagataac agaatggata gacagagttt tacagattta attcaaacaa aatttaaaat
      181 ggttcgtata gaggctggtt atacgcaaga tactatggcg caaacaattg gactttctaa
      241 aaagacttta gtacaaatcg aaaaagagag agtattacca aactggacaa cttgtatttc
      301 aatttgtgca ttattcagag actctgaagt attaaacagt acatttggct gtgatccatt
      361 agaaatcgtt caaacaattt caagaaatca ctgtgcatat ccaaaccatg caccaacaag
      421 tgatatttat tggaataaca ttgagactcg taatgggtac attttacaaa gtaacaaagt
      481 aagcaatatt tatcgtgtat taaatccaga taaccaacca attttcggta cttctaaaat
      541 gagagaagct gaaacatact ttaacagaaa tgctaaagaa gaattagtac atatctaggc
      601 ctatatactt ttaataaata ataaaagcga tgtgacacac ctgtttcgag aggtgaggca
      661 tcgctttttg tatgtaaact aataataaat tgagcagaaa gtgaaatgat taatgaatta
      721 aaaaataaaa atagtggtat aatgaataac tatgttgtca caaaggagtc aaaattatga
      781 atgcactatt tattatcata tttatgattg tagtaggggc gataattggt ggcattacta
      841 atgtaattgc aattagaatg ctgtttcacc cctttaaacc atactatata tttaaattta
      901 gagtcccatt tacaccaggt ttaataccga aaagacgcga agaaattgca actaaaattg
      961 gtcaagtgat tgaagagcat ttgcttacag aaactttaat taatgaaaaa ttaaaaagcg
     1021 agcaatcaca gcaagcaata gaatctatga ttcaacaaca gttacaaaag ttgacgaaag
     1081 atcaattgtc aataaaacaa attacttctc aactcgatat tgatttagaa caagtattac
     1141 aaactaatgg aaatcaatat attgaatcac aattgaataa ttattataca aagcatcaaa
     1201 accaaacaat agcatcttta ttgccaaatc aacttgtaac atttttagat cagcatgtag
     1261 ataacgcaac agacttatta tgtgatcgtg caagaaatta tttatcatct gcaaaaggca
     1321 cacaagatat taacgatatg ttggatactt tttttaatga gaaaggtaag ttaattggta
     1381 tgttgcaaat gtttatgaca aaagagagca ttgcagatcg aattcaacaa gaacttatac
     1441 gtttaacatc tcaccctaaa gcaagaacaa ttgtgacatc gttaattacc aatgaatatc
     1501 aaacttttaa agataaacca ttgaatgaac tgttagatgc ggcgcagttt aatgaaatcg
     1561 ctgaaaatct atcagtgtat gtaacaacat atgctagcaa acaagcgaat aagccagtgg
     1621 ttacgttaat gcctcaattc gttgattatt tagaaggtca actctctagc aaattagcaa
     1681 atttaatcat tgaacaatta tcgattcact tatctacaat tatgaaaaaa gtggatttac
     1741 gaggattaat tgaagaacaa attaatacgt ttgacttaga ttatattgaa aaattaatta
     1801 ttgaaattgc taacaaagaa ctaaagttga ttatgtcatt aggtttcatt ttaggtggta
     1861 ttattggatt tttccaaggt ttggttgcaa tctttgtcta aaaaagcgag atgtggtaaa
     1921 gtaatatcga acgttttaat aaacatcaca acaaaggagt gctataacca tggcagtaaa
     1981 tttatatgat tatgcaaatc aattagaaca agctttaaga gaaagcgaag aatacaaagc
     2041 aatcaaagaa gcattcgcta atgtaaaagc taacgaagaa tctaaaaagt tattcgacga
     2101 gttccgtgaa actcaaatta acttccaaca aaaacaaatg caaggtgaag aaattgctga
     2161 agaagattta caaaaagcgc aagaacaagc gcaagcaatt gaaaaagatg aaaacatctc
     2221 tgcattaatg aatgctgaac aaaaaatgag tcaagtattc caagaaatca accaaattat
     2281 cgttaaacca ttagacgaaa tttacgctga ctaatattaa aataatattt ttcaatcctt
     2341 taaatagagg aatagactgc cgacagagtc cgagactttg tgggtagttt ttttagtttt
     2401 gataacggaa gttagaggct ctctgtcaaa ttgggcagat gcgttcagta tcggaattta
     2461 ggctagtaaa cgtgtcctaa cttccttttt gcattttgga gtttaaagtt ttcaacataa
     2521 tactattagt tcggtcatgt atcggactga tgaaaaagtg tttcactttt aatgactcat
     2581 taagaacggc ctgaaaatgt ttgacgtatt aagtgcaatg atagttttga catttagctt
     2641 ctaattggtc attactgccg agcagaacta gtagagtaat catgtaaatc tttaatgtat
     2701 cagttggttc accagcagag ttaacagcta cagaaattga atttccgact gaaatttttg
     2761 aaaaaaatca acgcacgcta caaataaaat tttaaactgt tataaatgtg tctcaatttc
     2821 atatgttcat cgacgatatg aagcgtatta tggtaaaatg aagaaataat aaacttgtta
     2881 ataaataaaa catcacgatt tgactaaagc actttattat tgtgtagata atagtttttt
     2941 aacgaaataa aaatggcgac tggttttaat aaatcagcta atgaatcact acacctataa
     3001 gtatgaatat agtgattaga atgctttgta tagttggatt ttgcaaaatt gatgttagaa
     3061 cctttaatta aggagatatg gatgtatggt taaatttatt cattgttcgg atttacattt
     3121 agatagtcct ttcaaatcta agagtcatat aagccctaaa atttttgagg atgttcaaaa
     3181 aagtgcttat gaaagtttta aaaatattgt agatattgca ttacaacaag atgttgattt
     3241 tgtaattatc gcgggtgatt tatttgatag tgaaaacaga acattacgtg ctgaaatttt
     3301 cttaaaacag caatttgaac gtttacaaaa tgaacaaatc tttgtttatg tttgtcatgg
     3361 taatcacgac cctttatcat caaagatttc atcaaactgg ccagataatg tttctgtatt
     3421 ttcaaataaa gttgagacgt atgaagcaat tactaaatcg ggtgaaacaa tttatattca
     3481 cggatttagt tatgaaaata gagcaagtta tgagaacaag attgatgaat atccatcaag
     3541 tcaaggccaa aaaggcatac atattggtgt cttgcatggt acgtacagta aatcttcagt
     3601 taacgaaaga tataccgagt tcattttaga agatttaaac agtaaattgt atcattattg
     3661 ggctttaggt catatacatg aacgtcaaca attaagtgat atgcctgtaa ttaactattc
     3721 aggtaatatt caaggtagac attttaatga gcaaggtgaa aaaggttgct tattaatcga
     3781 gggtgaccac ttaaaattaa aaactaaatt ttatcctaca cagtatatta gatttgaaga
     3841 agcaactatt gaaacggata agacatctaa gcaaggttta tacgaggtca ttcaaaactt
     3901 taaagaacaa gtgagagaag aaggaaaagc cttttatcgt ttaacgcttg ttattaatag
     3961 tgagacatta atttcacctc aagatttatt acaagttgaa gaaatgatta cagattatga
     4021 agaaaacgaa aatcaatttg tatatattga tgagttaaaa atacaatatg cacaaaatga
     4081 tgagtcacct ttagttaatg aattttcagc ggaattatta gtcgatcaaa ctgtttttga
     4141 taaagcgatg tcagatttat atttaaatcc aagggcatct aagttcctag acgattatgg
     4201 aacattcgac catacagcat tagttaatcg tgctgaagaa atattaaaag ctgaaatgag
     4261 aggtgaacaa aatgataatt aaatcacttg aaatttatgg ttacggtcaa tttgttcaac
     4321 gtaaaattga atttaataaa aacttcactg aaatttttgg tgaaaatgaa gcgggtaaat
     4381 cgacgattca agcatttatc cattcgatat tatttggttt tccaactaaa aagtctaaag
     4441 agccaagact agaaccacgt ctaggtaacc aatacggtgg taaattagta cttattcttg
     4501 atgatggctt agagattgaa gttgaacgaa ttaaaggcag tgctcaaggt gatgtgaaag
     4561 tatatttacc taatggtgct gtgcgtgatg atgcttggtt acaaaagaaa cttaattata
     4621 tttctaaaaa gacatatcaa ggtatctttt catttgatgt actagggctt caagatattc
     4681 atagaaatct aaatgaaaaa caattgcaag attatttatt acaagcaggg gctttaggat
     4741 caactgaatt cacgtcaatg cgcgaagtga ttaatcgtaa aaaagatgaa ttatataaaa
     4801 aatcaggtaa aaatccgatc attaatcaac aaattgagca attaaaacaa ctagaaagtc
     4861 aaattcgtga agaagaagct aagctagaaa catatcatcg cttagtagat gatcgtgata
     4921 aatcatcacg tcgattagag aatttaaaac ataatttaaa tcaattatca aaaatgcatg
     4981 aagaaaaaca aaaagaggtt gctttacatg atcattcaca agaatggaag tctctagaac
     5041 aacagttaaa tattgagcca atcacattcc cagaaaaagg tgtagatcgt tacgaaaaag
     5101 cacgagcgca taagcaatcg ttagaaagag atattggttt aagaaatgag cgtttagccc
     5161 aacttaaaga agaagcgact caattagagc cagttaaaca atctgatatt gacgccttca
     5221 ttagtttgaa tcaacaagaa aatgaaatta aaaataaaga atttgaactt actgcaatcg
     5281 aaaaggatat tgcgaataaa caacgtgata aagatgaatt gcaagcaaat attggttggt
     5341 ctgaaacgca tcatgacgta gatagctctg aggcaatgaa aagttatgtc agtgagcaaa
     5401 tcaagaataa acaagaacaa gcggcataca ttaaacaatt agaacgtagt ttagaagaaa
     5461 ataaaatcga agataatgcg gttcatagcg aactagattc tgttgaaaaa aaaatagttc
     5521 ctgaagagac ttttgaaaag aaaaaagaat actcacaaca agtcattgaa ttaaacgaaa
     5581 aagagaactt gtatagcaaa ttgaaagaac gtttcgaaat tgagcaacaa gaaaaacaaa
     5641 aacgtcaaaa attgttacga acaacgttta ttcttttaac actagtaggt attggtttaa
     5701 ctgccttctc atttatttca aacaacatgt tgtttggtat tattttcgca gtattaactt
     5761 tagtatttgt tatcggtatc atcatgtcta aatcaaaaga agtagattat agcgaggcca
     5821 tcacagatga aatcgaagaa attaaagcac aactagccat tttagatgaa aattatgact
     5881 tagattttga tcttgatgag caatatcgca ttcgtgatca ctggcaacaa gctttgaaaa
     5941 ataaagatat tttagaagag aaacgtcagt atattgaagg tcgtttaaat gatgcgaaag
     6001 ggcgtcatga tgaattacaa tcaacagttg aaaacgttaa ggatgaatta tacttatcat
     6061 ctaaaatttc aaatgattta attgttgata gtatttctac aatggcgaat attaaagcat
     6121 tagatcaaca tatcagtgat ttaaatcaac aacgccagca attggttcaa gaattagata
     6181 cattctacaa tcatgctgaa gctgttacaa aattacaatt tgtttatttc aacaaattat
     6241 ctttattcca cgatgtgcaa caatggttga aatcagctga agacacgaat gaaaaatggc
     6301 gtattaatgc tgaaaatacc aaacttgtta caaatgaatt aaatcattta aatgctcaat
     6361 tagaagaaaa taataaagaa attacagcac tattcgattt tatcaatgtt ggtactgaag
     6421 aagattttta ccaacatcat gaagattacc aaacttacac tagtaatttg agtcgtttta
     6481 atgatttaac taaatatctt gagaaccaaa actattctta tgaattaagt tctagtttaa
     6541 gtgaaaaaac aactgcacaa cttgaagaag aagatcattt attggctact caagttgacg
     6601 aatataatga gcaatatctt gaaatgcaag cacaagtcag tgatttaagt gcacaaatca
     6661 atcacatgga aactgataca acgcttgcta atttgagaca tgaatatcac agtcttaaaa
     6721 atcaacttaa tgatatcgca aaagattggg caagtttaag ttatttacaa agtttagttg
     6781 atgaacacat taaacaaatt aaagataaac gtttgcctca agttattaat gaagcggtag
     6841 aaatattgaa gcatttaaca gatggcagat atacgatgat taactataat gaagattcaa
     6901 ttacggttaa acatgttaat ggtcaattat atgatcctgt tgaactaagt caatctacaa
     6961 aagaattact ttatgtagct ttacgtatca gtttaattaa ggtactacga ccatattatc
     7021 cgttcccatt aattgttgat gatgcatttg ttcattttga taaaaaacgt actgaaaaaa
     7081 tgttgaatta tttacgatca ttatcagaac actatcaagt actatacttt acatgtgtaa
     7141 aagataatat tgttccatca aaagaagtga ttacattaaa caaaatagag gaaggcggga
     7201 aacgatgaga aatatagaga atctaaatcc cggagattca gttgatcact ttttcttagt
     7261 gcataaagct acacagggtg taacagcaca aggtaaagat tatatgacat tacatttgca
     7321 agataaaagt ggtgaaattg aagcgaaatt ttggacggct acaaaaaatg atatggcaac
     7381 aatcaagcct gaagaaattg tacatgttaa aggtgacatc ataaactatc gcggaaataa
     7441 acagatgaaa gtcaaccaaa ttagactagc gacaactgaa gatcaattaa aaacagaaca
     7501 atttgtagat ggtgcacctt tatcaccggc agaaatacaa gaagagattt ctcattattt
     7561 gctagatatt gaaaatgcta atttacaacg tattacacgt catttattga aaaaatatca
     7621 agaacgattt tacacatatc cagctgctag ttctcatcat cataactttg cgagtggctt
     7681 aagctatcat gtattaacga tgttacgtat tgcaaaatca atttgtgaca tttatccatt
     7741 gttaaacaaa agtttgttat atagtggtat tattttgcat gatattggta aagtcagaga
     7801 attaagtggt cctgttgcga cgtcgtatac agtcgaaggt aacttattag gacacatctc
     7861 gattgcgagt gatgaagtag ttgaagcagc tcgtgaattg aacattgaag gagaagaaat
     7921 catgttgtta aggcatatga ttttatctca tcatggtaag ttagagtatg gttcgccaaa
     7981 actgccatac ttaaaagaag cagaaatttt atgctatatc gataatatcg atgctagaat
     8041 gaatatgttt gaaaaagcat ataaaaaaac tgacaagggt cagtttacag ataaaatatt
     8101 tggtcttgaa aatcgtagat tctacaatcc tgaatcactt gattaagaac taaaagatat
     8161 cggacagatg agtatactga aacatgagct catctgtccg atttttaatg cgaaaaaacc
     8221 gagcggccgt ggtatgattt ttgaaccacg gtcgctcggt tttgtgttat tggctcatgc
     8281 cggattgtcc gccttgtgcg ccaccttgtt taagtttttc agggtttaag attttatctt
     8341 cgacaactga tttaatatca cgatctttaa agtcaacatc gtattctttt aatagatctt
     8401 tgtatgcatc agttaataat tttggatttt tttgtacttt ctgatcgact aatttttctt
     8461 ttaggctttg tttttcactg ttaaagtctg ttggtttatc agctttaata atatgatatc
     8521 caaaacttga tttaacaacg tctgatactt caccatcttt aagtttaaat agtgcttttt
     8581 caaaatcttt atcagtttgt cctttaagaa cataacctaa ttcgccatct tttttagctg
     8641 aaccagtatc cattgattct tttttagcga tttcaccaaa tttacttgga tcttttgaaa
     8701 cttctttttg aatttcttca gctttttgtt tcgcttcttt atcatctaag ccttctttgt
     8761 cgcttttctt agatttaact ttaattaaaa tgtgtgaagc tttcttgctg tcttctttaa
     8821 tttcagaatc agagatttta attttatctg atagtaattc tttatgataa gcagcagtac
     8881 gtaaattttc tttatattta tcggctgtta aaccttgctg ttgaagggcc ttttcaaatt
     8941 tatctttacc gccgtattgc ttttgcattt tttcaatttg ctcgtcaatt ttcttatcgt
     9001 taactttatt tttatattta tcagctaaaa ttttatttaa catttcagta aacgatgcat
     9061 ttgcaatttg atctttaccg atttttttca ttgtatctgc aactgttaca tctccagctt
     9121 tagaagaaat taatgtattt tctttagagt ctgtggcact agcgccacaa gcgcctaata
     9181 ataaagcact agctgttact ggaacgatta atttgtttat catcttcata gttgaaactc
     9241 ctttgtaagt taatcatcgt gaatataaca tagttttata ttatcaccaa tcaataaccc
     9301 atgacatcag actagagcat taggtttagg ggtagaaatt gatgaaaata aaaaaacaag
     9361 gtctatatac atttgatttt aagctattac atagctgaaa aacaaataat aacaccttgc
     9421 tataattatt ttgttataaa tgatatggat ttttaatttt tttcaaaata ttaatacctg
     9481 tactatgttc ttctatatat tgtccataat tagaaaatat aattattttt aaatataata
     9541 aatctgtaat ggaaataccg aaattcaatg ccaataagaa cataaaataa tgtccatatt
     9601 gcggaaatga aattgttaga taaacgaaca ttgcagataa gataattaac ggcaatatta
     9661 agttaatgca aaaataaaat ttgtgtacag gttgattgac gtaggtatta tagaatataa
     9721 gccattttct tttagtcaac ttatgaactt taaacgattt tctatatggt aagaaaaata
     9781 ataaatgtat acttttatgt aatggatacg tcataaatac aagtaataaa aagatgagaa
     9841 aatgtctatc tgataatggc gtattagata aaaaatacat tacttcataa ctaactaaaa
     9901 acataatgat ggttgcaact gcactcataa atgcaattct aggcaaacca aatcgtgcat
     9961 tgatatcaat ttgtctttta catagaaaca tatcttacgc ctcatctctt ttcaatataa
    10021 gttagattat aactaactca ggttcagtaa ttcaatagta acatatcatg ttagaagaat
    10081 tgttatatat gaagtaaggg gcgacgtatt gtttgatttg aaacgcgaaa gtggggattg
    10141 gtaaaattgg ctgattgact agcgtagaag tagaatgcag aacaaatttc tgcgaacaca
    10201 tattcttgct aataaagcat cacttatgaa aaaggcgcgt gtgacatgag tatttgaaaa
    10261 cttgaataat ataaaaaatg gatatggcag ggcatatgca aaagcatctt ttgaccaatt
    10321 aagtcataca aatgctaaaa atatagtgat atgtaattat aacaaacacc agattaataa
    10381 tttgtgcaag taaggtatat gtaatgtata tataaggttc ggctcaatga aaatataagt
    10441 atgttgtttg tcgataatga tttaagtaaa gcgtaatcaa agtgcaagga taacacaatg
    10501 aatcctaagc aatgttttca atcaatttat aaatatgatt taagcgaaaa tcactacaaa
    10561 caatgtattc ctgtaatttg taatcaaatg ttcattcgag ccataaaaaa gagatgacaa
    10621 gaaatatcta atttctaatg tcatctcgtt tatttggcat ttaaatttaa aaaataaata
    10681 tgcagttact aataaaaata gttgtgatcg agaacgtaac ctgctactta gaaatttcgt
    10741 ttccaatatc ctcgccacga ttttgtaaat tttcgatgtg tgactgtaaa cgttcaatat
    10801 taggattgat gtcagatttg aagtttccaa gtaatgactt aatttcacca ccaattgaac
    10861 taccaaattc cgcactttcg tttttaattt gaacaccata gtttaaaatg tcattaaaac
    10921 tttgtttaat cgtttcaaat tcacgttgta gttctgattt tgaaccagta ggggcagtac
    10981 gatcgatcgt gttgttcttg acacttttgt cgtctcgtcc ttgaagtgca actacaaaac
    11041 cagctgctac accaacaccg ataccgaata gaatgcgtga tgctttcatt tatattctcc
    11101 tcacttttat catctgttat cttgataact cattttgttt aaaattgcta accttgatgt
    11161 tatcacttca aacgcaattg ttataatatt aatcatatta tacccgttcg agcttagatt
    11221 aagcatacat ttaaaattgt gcttgaattt gttcagcaat ttgttgtttt gcatcgttat
    11281 ctaaaatgtc ttcatgtgtt tcccacttat aaccaaatcc atcaatatca ttttcatatc
    11341 gaggaattaa gtggaaatga atatgaaata cagattgatc tgcaaactca ccattatttt
    11401 gaataatgtt taaaccatca ggattaaatg cacgcttaat agcatttgct actttaggta
    11461 atgctgcacc gatatgtttc attgtttctt catcagtttc aaagatatta gcagaagctt
    11521 ttttaggaat taataacgta tgtcctttag taacttgtga tatatctaaa aaggcataga
    11581 cataatcgtc ttcatatact ttaaagctag gaatttctcc agttaaaatt ttgccgaaaa
    11641 ttgtttctga catgatgact acactccttt tcaactagta ttaccattca ttataacatt
    11701 gtcgctaaaa attcgatatt aggacatgtg tatttaatat gagcatttta taatttttgg
    11761 tacaatataa gtcatggagg tgccttatga cagttaaagt agaacagctt acaggtggat
    11821 atggaaaacg ccctgtaatt aaagatataa attttgaatt aaacaaaggc gaaattgttg
    11881 gacttattgg ccttaatggc gctggtaaga gtacaacgat taaacatatg ctaggattgc
    11941 ttacacctat ggaaggatct ctatcaattt cagatatcaa cattaatgat gacatagagg
    12001 cttatagaag aaagttatct tatattccgg aatcaccggt tatttatgaa gaactcacat
    12061 tagaggaaca cattgagatg acagcaatgg catatgatat tgatcgtgat gaagcgatga
    12121 atcgagcaat gccattatta aagacattcc gtttagaaaa tgaattgaaa gtttttccga
    12181 gtcatttttc taaggggatg aaacaaaaag tcatgattat ttgtgcgttt atcgttaatc
    12241 ccgaattgta tattatagac gaaccattcc ttggcctaga tccattagga attcaatcca
    12301 tgttagattt aatggttgaa aagaaaaacg aaggtagaac cgttctaatg agtacacata
    12361 ttttagcaac agctgaacgt tactgtgatc gttttatcat actagacgaa ggtgaagtcg
    12421 ttgcatttgg agatttagaa gcattgagac aacaaactgg cttacataat caaacattag
    12481 acgatatata tattcatgtg acgcaaggtg gagatgtaca tgcgtaacca agcgaccact
    12541 ttatttaata aaagattaca tgcccttcgt aaagagaaaa attattataa taagtttata
    12601 tttaatggtc atttcatggt ctttttactt attttgctgg gtgcatttat ttttggatat
    12661 ggcgaatggt taaaacacat tccaacgaat atcaattttg cattaatagc agcagtgatt
    12721 gttgcgttga catccatttt tccaatgcga ccactcctaa aagaagcgga taaaatcttt
    12781 ttattaccat ttgaaaaaca catgtctcaa tttatgcgtc atgcgatttt atatagttac
    12841 tttgcgcgca tattaatcca actcattatt gttattgtga tgttcccgtt gttttataat
    12901 attaatcaac ataatgtggc attttacatt tgttttggag tcagtgcatt aatttttcca
    12961 tatgttggtt tacgcataag atggcaatgg tatcaatcgg gacttaaaac atggcaagtt
    13021 aatttaatat cattcatcat ctttgctcta acatattact tactgttagc tccaaaatgg
    13081 tacatcgcat ttgtgatggt tgctttgcct gtgttaatag aatttttagt taaaaaatat
    13141 aaacctggct ttttatatcc ttgggagaaa atgattgcta tcgaacatcg acatcatatg
    13201 aattattata aatttgttaa tatgttcacc gatgtaaaac atttgaaaga atctgcagtc
    13261 agaagaagtt atctagatat acttttacca gttccaaagg gtagtaaatt taactctaat
    13321 gcgatgtatt tattcttatt tattagaagc tttataagag ggagagacgc atttaatatt
    13381 atctttaggt tagtaattat tgcagtttta cttatgcttt ggttatcata tccattagtg
    13441 acagcaatta ttgggtgttt atttgtatat attatattgt tacaaatggc acaattttat
    13501 tcacagcaag catatggctt atggcctcaa gtgtggcccg tacctgaaga gaaggtaatc
    13561 aaagggtatg aacagttttt atatagatta atgtttgtta tttgtactgt gtttgcagtg
    13621 gcatttatta taaaacatat gacgttattc tatgttgtac tcattttcta tattgtaggt
    13681 ttattaacga ttagaagtat tattaaaaag ttaaaatatc aggaaacatt attacgagac
    13741 taaaaaactt ccattggcat gtatgttgta aaggtgcatg taatgttgaa cgccaaatga
    13801 tacggcgttc agattacatt agcatctata cgttaacagc ataaccaatg gaagttttct
    13861 tcgaatctat tcttttattg ggtataaata tctttcaaaa taacttgaat gttgtccgct
    13921 tgaaccaaag taatgactta atgcttcttt tgaaaaatga tctttaaaag catcagaatt
    13981 tttaaagtct tcataagttt gtcgatcagc aaagccaaag taaattttgt atgttgtacc
    14041 tttaacaggt ctcagcaatc gataactttt aaagccacca aagtttttga aattgtcatc
    14101 aacactgatt aatttctttt caagttgata aacatggtct tcagttgacg gaataaaaat
    14161 tgcgcaataa aaatgatctt cattgaatgc gcctatttct ttaataactt catatattga
    14221 aggtgatttc agtactgtat tttcttcagt ctcttcaaaa atcaccgatg aatcagtagt
    14281 tgaaaattgg aataaatgat gagatggatt attgattttt atctgattta aaaatccata
    14341 tgtgccataa gatgtatata atttcttcat atgaaaggtc ccccttatgt ttttatttat
    14401 tatacgacga taaactagtc attaccacta ttaatatacg gttaaagtta ctataataaa
    14461 tcatgcaaga caaaaagata tggagataat ccatcaagat tttaaaattt aaatacacaa
    14521 acaaatgatg tgtaatttaa tgtcagtttt atgacattta tttattgaaa atacgaacga
    14581 atgagcgata tgataatata gataagaatg attttaattt aggaggcctt tatggtgcat
    14641 aataaaaaca atacaatttt gaaaatgatt aaaggtgaag aaacgacaca tacacctgtt
    14701 tggtttatgc gacaagctgg ccgttcgcaa ccagaatatc gaaaattgaa agaaaaatat
    14761 tcactattcg atattacaca tcagccggag ttgtgcgctt atgtaacaca tttaccagtt
    14821 gataattatc atacagatgc agcaatttta tacaaagata ttatgacacc attaaagcca
    14881 attggtgtcg atgtagaaat taaatcgggt attggtccag tgattcataa tcctatcaaa
    14941 acaattcaag atgttgagaa actttctcaa atagaccccg aacgagatgt accatatgta
    15001 ttagatacaa ttaaactttt aacagaagaa aagttaaatg tgccgctaat aggatttact
    15061 ggggcaccat ttacattagc gtcatatatg attgaaggcg gaccatcgaa aaattacaat
    15121 tttacaaaag cgatgatgta tagagatgaa gcaacatggt ttgctttaat gaatcattta
    15181 gttgatgtat ctgttaaata tgtaacagct caagtcgaag caggtgccga attgattcaa
    15241 attttcgatt catgggtagg tgcattaaat gtcgaggatt acagacgtta cattaaacca
    15301 catatgattc gattaatcag tgaggttaaa gaaaaacatg atgtgccggt aattttattc
    15361 ggtgtaggtg ccagtcattt aatcaatgaa tggaatgatt tgccaattga tgtattaggc
    15421 ctagattgga gaacgtcgat taatcaggca cagcaattag gtgttactaa aacattacaa
    15481 gggaatttag atccatcaat tttattagca ccatggaatg tcattgaaga gagattgaag
    15541 tcaatattag atcaaggtat ggagaacggt aaacacatct ttaatttagg acacggtgtt
    15601 ttcccagaag tgcaaccaga gacgttacgt aaagtaagcg aattcgtaca cacatataca
    15661 caaagataat catagtatta cattgaagca catgaaagat aattcattta aaggaaggta
    15721 ttatcaatga ctaaaaaaat gggattatta gttatggctt atggcacacc ttataaagaa
    15781 agtgacatag agccatatta tacagatatt agacatggta aacgtccatc tgaagaagaa
    15841 cttcaagatt tgaaagatag atatgaattt ataggtggtt tatcaccatt agcaggtaca
    15901 acagatgacc aagctgatgc gctagtttca gcattaaata aagcatatgc agatgttgaa
    15961 tttaaactat atttaggatt aaaacatatt tcgccattta tcgaagatgc ggttgaacaa
    16021 atgcacaatg atggcattac tgaagcaatc actgtagtac tagcaccaca ctattcttca
    16081 ttttcagtag gatcatatga caaacgtgct gatgaagaag ctgcaaaata tggtattcaa
    16141 cttacacatg tgaaacatta ttatgaacaa cctaaattta ttgaatattg gacgaataaa
    16201 gtcaacgaaa cattagctca aataccggaa gaggaacata aagacacggt attagttgtt
    16261 tcggctcata gtttgccaaa aggtttaatc gaaaagaata atgatccata tccacaagaa
    16321 ctagaacata ctgcactttt aattaaagaa caatctaata ttgaacatat cgcgattggt
    16381 tggcaatctg aaggtaatac aggtacacct tggttagggc cagatgtaca agatttaaca
    16441 cgtgatttat atgaaaaaca tcagtataaa aactttatat atacgccagt aggttttgta
    16501 tgtgagcatt tagaggtgct ttatgacaat gattatgaat gtaaagttgt ttgcgatgat
    16561 attggtgcga attattatcg tccaaaaatg ccgaatacac atccattatt tatcggtgca
    16621 attgttgatg aaatcaagtc tatattttaa tgacgaaaga agcgtgaaac gttgtgacta
    16681 aatcagtggc tattatagga gcggggataa caggtttatc aagtgcatat tttttaaaac
    16741 agcaagatcc taatattgat gtaaccatct ttgaagcatc gaatcgtccg gggggaaaga
    16801 ttcaatcgta tcgtaaagat ggttatatga ttgaactagg gcctgaatct tatttaggta
    16861 gaaaaacgat tatgacagaa ttagcgaaag atattggatt agaacaagat attgttacaa
    16921 atacgactgg acaatcttat atttttgcga aaaacaaatt gtatcctatt ccaggtggat
    16981 caattatggg aattccgaca gatatcaaac cgtttgtgac aactaaatta atttcaccac
    17041 ttggaaagtt aagagcaggg ttagatttac ttaaaaaacc tactcaaatg cagaatggtg
    17101 acatttctgt tggtgcattt ttcagagcaa gattaggtaa tgaggtactt gagaatttaa
    17161 ttgagccttt aatgggtggt atttatggta ccgatattga taaattaagt ttgatgagta
    17221 cgtttcctaa ttttaaagaa aaagaagagg cattcggaag tctgataaaa ggtatgaagg
    17281 atgagaaaaa taagcgtctg aaacaaagac aattatatcc tggcgcacca aaaggacaat
    17341 tcaaacaatt taagcatggt ttaagctcat ttattgaagc attagaacaa gatgtgaaaa
    17401 ataaaggtgt gacaatacgc tacaatacgt cagtggatga tattattaca tctcaaaagc
    17461 aatataaaat tgtttacagt aatcaacaag aagaagtatt cgatggaata ttagtgacaa
    17521 caccacatca agtctttttg aattggttcg ggcaagatcc agcatttgat tactttaaaa
    17581 cgatggatag tacgactgtt gcaactgttg tattggcatt tgatgaaaaa gacattgaaa
    17641 atacttatga tggtactggc tttgtgattg cgagaacgag tgatacagac attaccgcat
    17701 gtacttggac atcgaaaaaa tggccattta ctacaccaga aggtaaggtt ttgattcgtg
    17761 cgtatgtagg taaaccaggt gatactgtgg ttgatgatca tacagataat gaattagtat
    17821 cgattgtacg tagagattta agtcaaatga tgacatttaa aggtgatcct gaatttacaa
    17881 ttgtcaatcg tttgccgaaa agtatgccac agtaccatgt cggtcatatt caacaaatta
    17941 gacagattca agcacatatt aaacaaacat atccacgact tagagtaact ggtgcatctt
    18001 ttgaagcggt tggactacct gattgtatta cgcaaggtaa agttgctgct gaagaagtaa
    18061 tcgcagagtt gtaagttaat tgttggatgg tgttggtgta ggtgcgacgc ctttagataa
    18121 tgtttgatga aatatagtca tttttaagtt atataatggt ggaagtaatg tgtaaatata
    18181 gatactttca gcgggaatta attttgtgaa attgaagcag agacaaaggt ttagctgttt
    18241 tttaatgata ttgaaatgat gtcaatacac tttaattaga aatgtcactt tgcgatataa
    18301 catttctaat taaggtgttt ttattttaca attataggta atcagtcatt tttttaaaaa
    18361 tagaaaagaa gtagtaagtt gaaaggagag aatgagatga cagatgtaat tattgtacat
    18421 tctatgcatg gaaatagtag aaatcattgg tatcagtggt tggagcataa cttaacttta
    18481 gaaggatatg acgtaacatt atttaatttt gaatcccctg aagcgaagac agtggatcag
    18541 tggattgaag ctatgacgaa acaaattaat gtacgcaaaa aggatacata ttttgtaaca
    18601 catggtttag gttcaatcac agctttaaaa tatattgaaa tgattgatca gccgattgaa
    18661 ggctttttta gtatagcggg ctttaaagaa gatgcagaaa atatagattt agatattgat
    18721 ttaagtaatg taaccattga ttacgataat attaaaaaga aagttgacaa tttttacgga
    18781 ttgagttcta aaaatgacaa atacgtttca tataaagaaa cccagcgttt aatgaatgca
    18841 ttagagggga acttgcgaat cgtggaagat ggagggcact tcttagaaga ggatggcttc
    18901 gaaacattta cagcgttgca agatcggatg caagattaca tgacacgata gttagtgtat
    18961 gggttgtgtt atgttgtgtc agtacgaagc atagtacttt agtgaaaaag attataatta
    19021 tattttaata gtttagaggt gtaggcatta taaaatttat gattcctaca tctttttcaa
    19081 tagttcatga gtaattatga caactattag acacttatat tataaaaggg aagaagaagc
    19141 gtttttttac acaaaaaact ttgaaaatgt cgttgacgta cactacaaaa atgaatatac
    19201 taatatttgt gttcaacaga gaacatgttg ctacgatatt taagtaatta tttaagagat
    19261 aacatttaaa ttaaattcaa aaagttcttg actttaggtt tttgattatg gtatattaat
    19321 taggtaattc aaaataatat tagcgcggga tggagcagtt cggtagctcg tcgggctcat
    19381 aacccgaagg tcggtggttc aaatccgcct cccgcaatac atagttttta atttaatagg
    19441 tctcgtagtg tagcggttaa cacgcctgcc tgtcacgcag gagatcgcgg gttcgattcc
    19501 cgtcgagacc gccattatta ttaccattac ggttcagtag ctcagttggt agagcaatgg
    19561 attgaagctc catgtgtcgg cagttcgact ctgtcctgaa ccattcttaa ttcatggcgg
    19621 ttgtggtgaa gtggttaaca catcggattg tggttccgac attcgagggt tcgatcccct
    19681 tcagccgccc cataatcgtt tacattagcg ggtgtagttt aatggcaaaa cctcagcctt
    19741 ccaagctgat gttgtgggtt cgattcccat cacccgctcc attattttct attattccac
    19801 agtagctcag tggtagagct atcggctgtt aaccgatcgg tcgtaggttc gagtcctacc
    19861 tgtggagcca tggctccttg gtcaagcggt taagacaccg ccctttcacg gcggtaacac
    19921 gggttcgagt cccgtaggag tcatacaaac agaagtgaaa tatcgcttct gtttttttat
    19981 tacatattta ttgttgagga gagttgtccg agttggccga aggagcacgc ctggaaagtg
    20041 tgtaggcgcc acaagcgtct cgagggttcg aatccctcac tctccgtaaa ggcgcttaaa
    20101 atggttttac ccattttaag cgctattttt aaggtttttt gtctattatc tgagtcactt
    20161 aatttaaaat ttgtttgttc aatagtaagt aggattgtta agtttaaaat cgtaatctaa
    20221 taatattagt gaatatttaa agattaaaaa cagaattttt cagtttatta agaaaaaaat
    20281 ttgtgaagga gggatattat taaaaatagt aaagtaatgt taaatgtatt attattaatt
    20341 ttaaatttaa ttgcaatatg tagtgtaaac aatgcatatg caaatgaaga agatcctaaa
    20401 atagagagtt tgtgtaagaa gtcaagtgta gaccctattg ctttacataa tattaatgat
    20461 gattatataa ataatcgatt tacgacagta aaatcaattg tatcaactac agaaaaattc
    20521 ttagacttcg atttattatt taaaagtatt aattggttag atggaatatc tgctgaattt
    20581 aaagatttaa aagtggaatt tagctcatca gcgatttcta aagaatttct aggaaagact
    20641 gttgatattt atggtgttta ctataaagca cattgtcatg gtgagcatca agtggatact
    20701 gcctgtacat atggtggggt aacacctcat gaaaataata aattaagcga gcctaaaaat
    20761 ataggagtag ctgtgtataa ggataatgta aatgttaata catttatcgt tactacagat
    20821 aaaaagaaag ttactgcaca agaacttgat attaaagtaa gaacaaaatt aaataatgca
    20881 tataaattgt atgacagaat gactagtgat gtacaaaaag gttatattaa atttcattct
    20941 cattcggagc ataaagaatc attttattat gatttatttt atattaaagg aaatttacca
    21001 gatcaatatt tgcaaattta taatgataat aaaacaatag attcatcaga ctatcatatt
    21061 gatgtttatt tatttacata acaatctgaa agttgatgga tatcaactta
//
LOCUS       DAPSKH010000050        21105 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPSKH010000050 DAPSKH010000000
VERSION     DAPSKH010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 21105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21105
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.050"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(96..560)
                     /gene="bstA"
                     /locus_tag="RPH49_001967"
     CDS             complement(96..560)
                     /gene="bstA"
                     /locus_tag="RPH49_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol transferase BstA"
                     /protein_id="HDY5125097.1"
                     /translation="MTTKTVFDVIDMGLGYLVNVYDAWKVEKVLDDYHKPFSNTIHWQ
                     FGHVLTIFESALAVAGKENIDLNIYRPLFGNGSSPDEWKDEVPSIERILEGLQTLPER
                     ARNLTEDDLAIELKQPIVGCNNLEELLVLNAIHIPLHAGKIEEMSRILKNLK"
     gene            complement(663..1301)
                     /gene="pcp"
                     /locus_tag="RPH49_001968"
     CDS             complement(663..1301)
                     /gene="pcp"
                     /locus_tag="RPH49_001968"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDY5125098.1"
                     /translation="MHILVTGFAPFDNQDINPSWEAVTQLENIIGTHTIDKLKLPTSF
                     KKVDTIINKTLASNHYDVVLAIGQAGGRNAITPERVAINIDDARISDNDDFQPIDQAI
                     HLDGAPAYFSNLPVKAMTQSIINQGLPGALSNSAGTFVCNHVLYHLGYLQDKHYPHLR
                     FGFIHVPYVPEQVIGKPDTPSMPLEKIVAGLTAAIEAISNDEDLHLALGTTE"
     gene            complement(1453..2409)
                     /locus_tag="RPH49_001969"
     CDS             complement(1453..2409)
                     /locus_tag="RPH49_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDY5125099.1"
                     /translation="MNYQVLLYYKYTTIDDPEQFAQDHLAFCKAHHLKGRILVSTEGI
                     NGTLSGTKEETEQYMAHMHADERFKDMVFKIDEAEGHAFKKMHVRPRKEIVALDLEDD
                     VDPRHTTGQYLSPVEFRKALEDDDTVIIDARNDYEFDLGHFRGAIRPNITRFRDLPDW
                     IKENKALFADKKVVTYCTGGIRCEKFSGWLLKEGFEDVAQLHGGIATYGKDPETKGEY
                     WDGKMYVFDDRISVDINQVEKTIIGKDWFDGKPCERYINCANPECNKQILVSEENEAK
                     YLGACSYDCAKHERNRYVQANNISDNEWQQRLTNFDDLHQHA"
     gene            2653..3624
                     /locus_tag="RPH49_001970"
     CDS             2653..3624
                     /locus_tag="RPH49_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMP-30/gluconolactonase/LRE family protein"
                     /protein_id="HDY5125100.1"
                     /translation="MSQQDLPTLFYSGKSNSAVPIISESELQKITAEPWLEISKKGLQ
                     LEGLNFDRQGQLFLLDVFEGNIFKVNPETKEIKRPFISHKANPAAIKIHKDGRLFVCY
                     LGDFKSTGGIFTATENGDNIQDIIEDLSTTYCIDDMVFDSKGGFYFTDFRGYSTNPLG
                     GVYYVAPDFRTVTPIIQNISVANGIALSTDEKVLWVTETTANRLHRIALEDDGVTIQP
                     FGATIPYYFTGHEGPDSCCIDSDDNLYVAMYGQGRVLVFNKRGYPIGQILIPGRDEGH
                     MLRSTHPQFIPGTNQLIICSNDIEMGGGSMLYTVNGFAKGHQSFQFQ"
     gene            complement(4102..4617)
                     /locus_tag="RPH49_001971"
     CDS             complement(4102..4617)
                     /locus_tag="RPH49_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenoid-binding protein"
                     /protein_id="HDY5125101.1"
                     /translation="MTNFTFDGAHSSLEFQIKHLMVSKVKGSFDQFDVAVEGDINDFS
                     TLKATTTIIPSSINTKNEARDNHLKSGDFFGTDEFDKITFVTKSITENKVVGDLTIKG
                     ITNEETFDVEFNGVSKNPMDGSQVTGIIVTGTINREKYGINFNQALETGGVMLGKDVK
                     FEASAEFSISE"
     gene            4805..4912
                     /locus_tag="RPH49_001972"
                     /pseudo
     CDS             4805..4912
                     /locus_tag="RPH49_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
     gene            5030..6154
                     /locus_tag="RPH49_001973"
     CDS             5030..6154
                     /locus_tag="RPH49_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDY5125102.1"
                     /translation="MHKKYLLLFFLLLSVALLYSCSKQNEKAQNKYVNPNEYAKHKSK
                     MDEHWETYHGQVYHVFYHPLITDPKVAFTGDTHQAKGNNDWMITVSEFKKSLNELYKN
                     NYIIVNPHDVYDLSSHHVKAKKIKLPKGKKPLIISIDDMNYYSYMRHHGYADRLVLDK
                     NKHVVSETTDSKGHATYSDDNDIVPILNKFVKEHPDFSLNGEKGVVALTGYEGVLGYR
                     TNELTSKDYTKNKKAVEEVVRAMKRDGWSFASHSYGHINFEKTSLEGIKRDTKRWKDE
                     VEPIVGKTDMFVFPHGAQDRYTQAYDYLVDEAEFKFIAGVGPNNFTDISATNVYQDRV
                     AIDGLNLFEFKYKLKPFFNPENVYSKQDRQFFKGNRDYEE"
     gene            6458..7276
                     /locus_tag="RPH49_001974"
     CDS             6458..7276
                     /locus_tag="RPH49_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase regulatory
                     subunit"
                     /protein_id="HDY5125103.1"
                     /translation="MNNSEQLIALKESETAFLKYFNKADYELVDFSVVEKLDWKQLNH
                     EDLQQMGERNFWQHEHQIYALRNDFTDQLLRYYSMYPTAATKVAYTGLIIRNNEAAVQ
                     VGLENYAPSLANVQQSLKLFIQFIQQQLRDNVHFVVLGHYQLLDALLDKSLQTPDILS
                     MIEERNLSGLVTYLSTEHPIVQILKENTQQQLNVLEHYIPNDHPALVELKIWERWLHT
                     QGYKDIHLDITAQPPRSYYTGLFIQCHFAENESRVLTGGYYKGSIEGFGLGLTL"
     gene            7294..7908
                     /locus_tag="RPH49_001975"
     CDS             7294..7908
                     /locus_tag="RPH49_001975"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDY5125104.1"
                     /translation="MLRIAIAKGRLMDSLINYLDAIEYTTLSETLKNRERQLLLSVDN
                     IECILVKGSDVPIYVEQGMADIGIVGSDILDERQYNVNNLLNMPFGACHFAVAAKPET
                     TNYRKIATSYVHTAETYFKSKGIDVELIKLNGSVELACVVDMVDGIVDIVQTGTTLKA
                     NGLVEKQHISDINARLITNKAAYFKKSQLIEQFIRSLEVSIANA"
     gene            7901..9151
                     /locus_tag="RPH49_001976"
     CDS             7901..9151
                     /locus_tag="RPH49_001976"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDY5125105.1"
                     /translation="MLNAQQFLNQFSLEAPLDESLYPIIRDICQEVKVHGDKALKMYN
                     LTFDHTKTDHLEISHEQIKAAFDTLDEKTKQALQQSYERIKAYQESIKQTNQQLEESV
                     ECYEIYHPLESVGIYVPGGKASYPSTVLMTATLAQVAGVENIVVVTPPQPNGVSQEVL
                     AACYITQVNQVFQVGGAQSIAALTYGTETIPKVDKIVGPGNQFVAYAKKYLFGQVGID
                     QIAGSTEIALIIDDTTDLDAIVYDVFAQAEHDELARTYVISEDAQVLKDLESRIAKAL
                     PNVDRYDIVSKSIANQHYLIHASNFDEACHVMNTIAPEHASIQTVNPQPYIEKVKYVG
                     ALFIGHYSPEVIGDYVAGPSHVLPTNRTARFTNGLSVNDFLTRNTVIHLSKDTFEQIA
                     DSAQHIAHVEALYNHQQSILIRQS"
     gene            9167..10180
                     /locus_tag="RPH49_001977"
     CDS             9167..10180
                     /locus_tag="RPH49_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate aminotransferase family
                     protein"
                     /protein_id="HDY5125106.1"
                     /translation="MIYIDKNESPVTPLDEKTMTSIISATPYNLYPDAAYEQFKEAYA
                     KFYGLSPEQIIAGNGSDELIQKLMLIMPEGPALTLNPDFFMYQAYAAQVNREIAFVDA
                     GSDLTFDLETILTKIDEVQPSFFIMSNPHNPSGKQFDTAFLTAIADKMKALNGYFVID
                     EAYLDYGTAYDVELAPHILRMRTLSKAFGIAGLRLGVLISTAGTIKHIQKIEHPYPLN
                     VFTLNIATYIFRHREETSRFLTMQRQLAEQLKQIFDTHVADKISVFPSNANFVLTKGS
                     AAQQLGQYVYEQGFKPRFYDEPVMKGYVRYSIATEPQLNQLEEIVKEWSAKYDLSKTT
                     KHS"
     gene            10149..10727
                     /gene="hisB"
                     /locus_tag="RPH49_001978"
     CDS             10149..10727
                     /gene="hisB"
                     /locus_tag="RPH49_001978"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazoleglycerol-phosphate dehydratase HisB"
                     /protein_id="HDY5125107.1"
                     /translation="MIYQKQRNTAETQLNISISDDQSPSHINTGVGFLNHMLTLFTFH
                     SGLSLNIEAQGDIDVDDHHVTEDIGIVIGQLLLEMIKDKKHFVRYGAMYIPMDETLAR
                     VVVDISGRPYLSFNASLSKEKVGTFDTELVEEFFRAVVINARLTTHIDLIRGGNTHHE
                     IEAIFKAFSRSLGIALTATDDQRVPSSKGVIE"
     gene            10724..11302
                     /gene="hisH"
                     /locus_tag="RPH49_001979"
     CDS             10724..11302
                     /gene="hisH"
                     /locus_tag="RPH49_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDY5125108.1"
                     /translation="MIVIVDYGLGNISNVKRAIEHLGYEVVVSNNQNIIDQAETIILP
                     GVGHFKDAMSEIKRLNLDAILAKNTDKKMIGICLGMQLMYEYSDEGDASGLGFIPGNI
                     SRIQTEYPVPHLGWNNLVSKHPMLNQDVYFVHSYQAPMSENVIAYAQYGTDIPAIVQF
                     NNYIGIQFHPEKSGTYGLQILRQAIQGGFIND"
     gene            11295..11999
                     /locus_tag="RPH49_001980"
     CDS             11295..11999
                     /locus_tag="RPH49_001980"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-((5-
                     phosphoribosylamino)methylideneamino)imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDY5125109.1"
                     /translation="MIELWPAIDLIGSTSVRLTEGKYDSEEKMSRSAEESIAYYSRFE
                     CVNRIHIVDLIGAKAQHAREFDYIKSLRRLTTKDIEVGGGIRTKSQIMDYFAAGINYC
                     IVGTKGIQDTDWLKEMAHTFPGRIYLSVDAYGEDIKVNGWEEDTELNLFSFVRRLSDI
                     PLGGIIYTDIAKDGKMSGPNFELTGQLVKATTIPVIASGGIRHQQDIQRLASLNVHAA
                     IIGKAAHQASFWEGLK"
     gene            11996..12754
                     /gene="hisF"
                     /locus_tag="RPH49_001981"
     CDS             11996..12754
                     /gene="hisF"
                     /locus_tag="RPH49_001981"
                     /EC_number="4.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDY5125110.1"
                     /translation="MIKKRIIPCLDVKDGRVVKGIQFKGLRDIGNPVDLAMYYNEAGA
                     DELVFLDISKTEEGHSLMLEVIEQTASRLFIPLTVGGGIQSLDDITQLLNHGADKVSL
                     NSSALKNPQLIKQASDKFGRQCICIAIDSYYDPERKAHYCCTHGGKKMTNIKVYDWVQ
                     QVEQLGAGELLVTSMGHDGMKQGFDIEHLAKIKSLVNIPIIASGGGGNAQHFVELFDQ
                     TDVSAGLAASILHDRETTVQSIKEVIRQGGIAVR"
     gene            12751..13383
                     /locus_tag="RPH49_001982"
     CDS             12751..13383
                     /locus_tag="RPH49_001982"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDY5125111.1"
                     /translation="MTNYKIDFSKGLVPAILQDNQTKQVLMLGYMNQEAFDKTIEDGV
                     VCFYSRSKQRLWTKGETSGHTQLVKDIHVDCDNDTILIDVIPNGPTCHTGSQSCFNTE
                     VPFSVQTLAQTVQDSAQSNNEKSYTKYLLTEGIEKITKKYGEEAFEVVIEAIKGDKKA
                     FVSEVADELYHLFVLMHALGVDFSEIEAELARRHHKRNNFKGERQNIEQW"
     gene            14469..16511
                     /gene="lip1"
                     /locus_tag="RPH49_001983"
     CDS             14469..16511
                     /gene="lip1"
                     /locus_tag="RPH49_001983"
                     /EC_number="3.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK domain-containing triacylglycerol lipase
                     Lip1"
                     /protein_id="HDY5125112.1"
                     /translation="MKSQNKYSIRKFSVGASSILIATLLFLSGGQAQAAEKQVNMGNS
                     QEDTVTAQSIGDQQTRENANYQRENGVDEQQHTENLTKNLHNDKTISEENHRKTDDLN
                     KDQLKDDKKSSRNNKNIQRDTTKNNNANPSDVNQGLEQAINDGKQSKVASQQQSKEAD
                     NSQDSNANNNLPSQSRTKEAPSLNKLDQTSQREIVNETEIEKVQPQQNNQANDKITNY
                     NFNNEQEVKPQKDEKTLSVSDLKNNQKSPVEPTKDNDKKNGLNLLKSSAVATLPNKGT
                     KELTAKAKDDQTNKVAKQGQYKNQDPIVLVHGFNGFTDDINPSVLAHYWGGNKMNIRQ
                     DLEENGYKAYEASISAFGSNYDRAVELYYYIKGGRVDYGAAHAAKYGHERYGKTYEGI
                     YKDWKPGQKVHLVGHSMGGQTIRQLEELLRNGSREEIEYQKKHGGEISPLFKGNNDNM
                     ISSITTLGTPHNGTHASDLAGNEALVRQIVFDIGKMFGNKNSRVDFGLAQWGLKQKPN
                     ESYIDYVKRVKQSNLWKSKDNGFYDLTREGATDLNRKTSLNPNIVYKTYTGEATHKAL
                     NSDRQKADLNMFFPFVITGNLIGKATEKEWRENDGLVSVISSQHPFNQAYTNATDKIQ
                     KGIWQVTPTKHDWDHVDFVGQDSSDTVRTREELQDFWHHLADDLVKTEKVTDTKQA"
     gene            complement(16902..17954)
                     /gene="icaC"
                     /locus_tag="RPH49_001984"
     CDS             complement(16902..17954)
                     /gene="icaC"
                     /locus_tag="RPH49_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide intercellular adhesin
                     biosynthesis/export protein IcaC"
                     /protein_id="HDY5125113.1"
                     /translation="MKKIRLELVYLRAIICAIIIVTHLLTQITLKHENMEGGSLVLQF
                     YIRNIVIFGTPCFIILSQLLTTLNYQKVTYRYLTTRVKYILIPYILMGLFYSYSESLL
                     TDSSFNKQFIENVLLGQWYGYFIVVIMQFFILSYIIFKINYNLFNSKILLLLSFILQQ
                     SFLYYFTNNTAFHDTVLHYYPLSENTIIFGWIFYFFLGAYMGYNYERVLNFLERYLVI
                     MIVLAVATYFVFIALANGDYWNVTSFSYSLTPYNSIMFIVILGICTHFKTMLFNTIQM
                     ISAFSFFIYLLHPIILDSLFAYTNIFEDNTMVFLAISLLFILGLCIGVGMILREFYIF
                     RFIIGKQPYKLNINAY"
     gene            complement(17941..18813)
                     /gene="icaB"
                     /locus_tag="RPH49_001985"
     CDS             complement(17941..18813)
                     /gene="icaB"
                     /locus_tag="RPH49_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intercellular adhesin biosynthesis
                     polysaccharide N-deacetylase"
                     /protein_id="HDY5125114.1"
                     /translation="MKYRKLIILVLSILIILPVSTLDGHHIANADDDSPKKLKYKENS
                     ALALNYHRVRKANFLNNFIYFFSSSKEIKNYSVSQSQFESQIKWLKSHDAKFLTLKEF
                     LYYKKKGKFPKRSVWINFDDMDETIYENAYPILKKYKIPATGFIITGHVGEENFHNLD
                     MISKKELKEMYKTGLWEFETHTHDLHNLSKNNKSKLMKSSEATIIKDLNKSEKYLTKN
                     FKKSQKTIAYPYGLMNDDKLPVIKKAGLKYGFSLEEKAVTPNSNDYYIPRILISDDAF
                     EHLIKRWDGFHEKD"
     gene            complement(18810..19115)
                     /gene="icaD"
                     /locus_tag="RPH49_001986"
     CDS             complement(18810..19115)
                     /gene="icaD"
                     /locus_tag="RPH49_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular adhesion protein D"
                     /protein_id="HDY5125115.1"
                     /translation="MVKPRQREYPTLKSSLNIVRETALIAISCVFWIYCLVVLLVYIG
                     TIFEIHDESINTIRVALNIENTEILDIFETMGIFAIIIFVFFTISILIQKWQRGRES"
     gene            complement(19079..20317)
                     /gene="pgaC"
                     /locus_tag="RPH49_001987"
     CDS             complement(19079..20317)
                     /gene="pgaC"
                     /locus_tag="RPH49_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDY5125116.1"
                     /translation="MQFFNFLLFYPVFMSIYWIVGSIYFYFTREIRYSLNKKPDINVD
                     ELEGITFLLACYNESETIEDTLSNVLALKYEKKEIIIINDGSSDNTAELIYKIKENND
                     FIFVDLQENRGKANALNQGIKQASYDYVMCLDADTIVDQDAPYYMIENFKHDPKLGAV
                     TGNPRIRNKSSILGKIQTIEYASLIGCIKRSQTLAGAVNTISGVFTLFKKSAVVDVGY
                     WDTDMITEDIAVSWKLHLRGYRIKYEPLAMCWMLVPETLGGLWKQRVRWAQGGHEVLL
                     RDFFSTMKTKRFPLYILMFEQIISILWVYIVLLYLGYLFITANFLDYTFMTYSFSIFL
                     LSSFTMTFINVIQFTVALFIDSRYEKKNMAGLIFVSWYPTVYWIINAAVVLVAFPKAL
                     KRKKGGYATWSSPDRGNTQR"
     gene            20482..21042
                     /gene="icaR"
                     /locus_tag="RPH49_001988"
     CDS             20482..21042
                     /gene="icaR"
                     /locus_tag="RPH49_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ica operon transcriptional regulator IcaR"
                     /protein_id="HDY5125117.1"
                     /translation="MKDKIIDNAITLFSEKGYDGTTLDDIAKSVNIKKASLYYHFDSK
                     KSIYEQSVKCCFDYLNNIIMMNQNKSNYSIDALYQFLFEFIFDIEERYIRMYVQLSNT
                     PEEFSGNIYGQIQDLNQSLSKEIAKFYDESKIKMTKEDFQNLILLFLESWYLKASFSQ
                     KFGAVEESKSQFKDEVYSLLNIFLKK"
BASE COUNT         7576 a         3219 c         3713 g         6597 t
ORIGIN      
        1 ggtcactttt aatctgtatg taagcagact aaaagtggcc ttttaaaaaa taaaaaaatc
       61 tgttaacgtg ttgttaacgg ttaataagca catatttatt ttaaattttt taatatacga
      121 gacatctctt caattttacc agcatgaagt gggatgtgaa tggcatttaa tactaataac
      181 tcttctaagt tattacaacc gacaattggc tgtttcaatt caattgctaa atcatcttca
      241 gttagatttc gtgcacgttc aggtaaagtt tggagacctt ctaaaatcct ttcaatactc
      301 ggtacttcat ccttccattc atctggagac gaaccatttc cgaataaagg tctatagata
      361 tttaaatcaa tattctcttt accagcaaca gctaaggccg attcaaaaat tgttaataca
      421 tgaccaaatt gccaatgaat ggtattagaa aaaggcttat gataatcatc aagtaccttt
      481 tcaactttcc aagcatcata cacatttact aaatatccta accccatatc aatgacatca
      541 aatactgttt ttgtagtcat tattaattcc tcccccataa ataaaacata cttccgtaag
      601 tattacccta ttaacaaagt tgttagtcat ttaaggaatg tattttattg gtgtacttat
      661 aactattccg ttgtgcccag ggctaggtgt aaatcctcat cattagaaat agcttcaatg
      721 gctgcagtca aacctgcaac tatcttttct aatggcatag atggtgtatc gggtttacca
      781 atgacctgct ctggtacgta tggcacatga ataaatccga atcgtaggtg agggtaatgc
      841 ttatcttgta aataacctaa gtgataaagt acgtgattac atacgaacgt acctgcgcta
      901 tttgaaagtg ctccaggaag tccttgatta ataatacttt gagtcattgc tttaactggt
      961 aaatttgaaa aataagctgg cgcaccgtct aaatgaatgg cttgatcaat aggttgaaaa
     1021 tcatcattat ctgaaatacg tgcatcatca atattaatgg cgacacgttc tggggtaatg
     1081 gcatttctac caccagcttg tcctatagct agtacaacat catagtgatt agatgccaac
     1141 gttttattta taatagtatc tactttctta aaagaggttg gtagttttaa tttatcgatg
     1201 gtatgtgtgc caataatatt ctctagttga gtcacagctt cccaagaagg attaatatct
     1261 tgattgtcaa aaggcgcaaa ccctgttact aaaatgtgca ttttaagaca ccccgcagta
     1321 ttaaaattta atttagtata acatgcgcat aattaaaaac atatcaggtt atgcatgcgc
     1381 ataaaaaaca gccttgaaaa acctttataa atcggatttt caaagcgtgt tttgaaaggt
     1441 attttattaa aactaagcat gttgatgtaa atcatcaaag tttgttaaac gttgttgcca
     1501 ctcattatca ctaatattat tcgcttgaac ataacgatta cgctcatgtt tagcacaatc
     1561 ataagagcat gcacctaaat atttagcttc gttttcttcg gaaactaata tttgtttatt
     1621 acattctggg ttagcgcaat taatataacg ttcacatggt ttgccatcaa accaatcctt
     1681 accaataatt gttttttcaa cttggttgat atcaacactg atacggtcat caaatacgta
     1741 cattttaccg tcccaatatt caccttttgt ttcaggatct ttaccatatg tagcaatacc
     1801 gccatgaagt tgagctacat cttcgaaacc ttcttttaaa agccatccag aaaatttttc
     1861 acatcgaatg ccaccagtac agtacgtaac cactttttta tctgcaaata acgctttatt
     1921 ctctttaatc cagtcaggca aatctctaaa gcgcgtgata tttggacgaa ttgcacctcg
     1981 gaaatgaccc aaatcaaatt cataatcatt acgtgcatca ataatgactg tgtcatcatc
     2041 ttcaagagct tttctaaatt ctacaggtga taaatattgg ccagttgtgt gtcttggatc
     2101 gacgtcatct tctaaatcta aagcaacgat ttcttttcga ggacgtacat gcattttctt
     2161 aaaagcatgt ccttcagctt catcaatttt aaacaccata tctttgaatc gttcatcggc
     2221 atgcatatgt gccatatatt gttcggtttc ttcttttgta ccagataatg tgccgttaat
     2281 accttctgta gaaacaagaa ttctaccttt taaatggtgt gctttacaaa aggctaagtg
     2341 atcctgagca aactgttcag ggtcatcaat cgtcgtatat ttataatata aaagaacttg
     2401 atagttcata ggttaatctc cttctaaaaa catgttataa gcatgttaat ttttaaaata
     2461 aagcgtcaat acgcatattt gtctacgtcc ttcattttaa cagagttgta ttgtcattca
     2521 atatttctag cttgaaatca gccactagac cgataaaata gataaatgaa accgttatca
     2581 tttgatttaa atgtttcctt gtttaaaata aaaatgatag ttaaaacgaa tgaaatgaaa
     2641 ggaatgatca tgatgtcaca acaagattta cctacattat tttatagcgg gaagtctaat
     2701 agtgctgttc caattatatc tgaaagtgaa ttacaaaaaa ttacagctga accatggctt
     2761 gaaatttcca aaaaaggatt gcaattagaa ggattgaact ttgatcggca aggacaacta
     2821 tttttattgg atgtattcga aggtaatatt ttcaaagtca atcctgaaac gaaggaaatc
     2881 aaacgacctt ttataagtca caaagcgaat cctgcagcaa tcaaaataca taaagacggc
     2941 cgattattcg tttgttattt aggagatttt aaatctacag gagggatttt tacagctaca
     3001 gaaaatggtg acaacataca agatattatt gaagatcttt caacaacata ttgtattgat
     3061 gacatggtat ttgattctaa aggtggattt tattttacag attttagagg atactctacc
     3121 aatccactag gaggcgttta ttatgttgcg ccggacttta gaacagtgac gcctatcatt
     3181 caaaatatta gcgtagcaaa tggtattgct ctaagtacag atgaaaaagt actatgggta
     3241 acagaaacta cagccaatcg attacatcgc attgcacttg aagatgatgg tgtgacgata
     3301 caaccatttg gagctactat accgtactat tttacaggtc atgaaggacc agactcatgt
     3361 tgtattgata gtgacgataa tttatacgta gcaatgtatg gtcaaggtcg agtgttagtt
     3421 tttaataaaa ggggttatcc aataggacaa atattgatac caggccgaga tgaagggcat
     3481 atgttacgtt ctactcatcc gcaatttata cctggaacaa atcaactcat catttgttcc
     3541 aatgatatag aaatgggcgg aggatctatg ctttatacag ttaatggctt tgcaaaaggt
     3601 catcaaagtt ttcagtttca ataagaccta cctgaatgaa aggcgtctta atataagttt
     3661 aaatcttagc aatttttaat ttagaagtta aatataattt gcttcaattt gtaaaatgaa
     3721 gttttgtata acgtaaatag gcaatattta atataagaaa gtataaagaa gaattttctt
     3781 gattatttct aatgaagcca atgccaattt aataaggagt tgtttatttt ggctatttat
     3841 attttttgta caatactagt tttagtcgca gttggagcac ttttgacaaa tagaataagg
     3901 gataaaaaag ataaaaggct agatatttta tctagtgtat tacttttaat ttcatcaata
     3961 acattgttac tttatggtgt tattatcaat taagttaaat atgattttta atttagaagt
     4021 taaaaaatgc caactatacc tagggatgat atagttggca tttcgtatat atattaaaac
     4081 aatgaggatt gtgtaatgag attattctga gattgaaaat tcagctgatg cttcgaattt
     4141 cacatcttta cctagcatta ctccaccagt ttcaagtgct tggttgaagt taatgccata
     4201 tttttctcta ttgattgtac cagtaacaat aatacctgtt acttgagaac catccatagg
     4261 attcttactt actccgttga attcaacgtc gaatgtttct tcgttagtga tacctttaat
     4321 tgttaaatca ccaacaactt tgttttctgt aattgatttt gtcacaaaag tgattttatc
     4381 aaattcatca gtaccaaaga aatcaccaga ttttaagtgg ttatcacgtg cttcgttttt
     4441 agtgttaatt gagcttggaa taattgttgt agtagctttc aaagtactga agtcattaat
     4501 atctccttca acagctacat caaattgatc aaatgaacct ttcactttag aaaccattaa
     4561 atgtttaatt tggaattcta aactactgtg tgcaccatca aaagtaaagt tagtcataat
     4621 ataaaacctc catattttta tctcttagat atatttttta tacttgatat acatacaata
     4681 ccacctaaaa aacaaagatg caagcatttt atttcgaatt cgaatatttt tctgtgatgt
     4741 atttaaagaa tgacctataa aacaccacac tattgttata ccctagtcaa ttaattcaaa
     4801 cataaataag tgtaaccaac gttcaataaa tttagcagaa aggcttaaat tcaagcgaga
     4861 caaagctatg gacgacatta tcaatcaagg agatattgtg ttttataaat aaaatactat
     4921 gacattatct aaaaaataaa attaaaatac caacagtttc ttaaaaagtt atgagccaca
     4981 taataaaaat gttataattg tgcataataa aacataggga gaatgtttaa tgcataaaaa
     5041 atatttattg ctattttttc tgttattatc agttgcattg ttatatagct gttccaagca
     5101 aaatgagaaa gctcaaaata aatatgttaa tccaaatgag tatgcaaagc ataaatcgaa
     5161 aatggatgaa cattgggaaa catatcacgg ccaagtttat catgtgtttt atcacccatt
     5221 aattacagac ccaaaagttg cgtttacagg agatacacac caagctaagg gcaacaatga
     5281 ttggatgatt actgtaagtg aatttaaaaa atcattgaac gaattatata aaaataatta
     5341 catcatcgtt aatccacatg atgtatacga cttatcatct catcatgtaa aagccaaaaa
     5401 aataaaattg ccgaaaggta aaaagccact aatcatctca attgatgata tgaattacta
     5461 tagttacatg agacaccatg gttatgctga ccgtttagta ctcgataaaa ataaacatgt
     5521 tgtttctgaa acgacagact caaaaggcca tgctacttat tctgatgaca atgatatcgt
     5581 gccaatttta aataaatttg taaaagagca tccagatttt tctttaaatg gtgaaaaagg
     5641 tgttgttgct ttaaccggtt atgagggcgt attaggttat cgcacgaatg aattaacgag
     5701 taaagattat acaaagaata aaaaggcagt tgaggaagtt gttcgcgcaa tgaaacggga
     5761 tggatggtca tttgcgagtc attcatatgg tcacattaat tttgaaaaaa catctttaga
     5821 aggtattaaa cgtgatacta aaagatggaa agatgaagtt gaaccaattg taggtaaaac
     5881 agatatgttt gtatttccac atggcgcaca ggatagatat acacaagcgt atgattattt
     5941 ggtagatgaa gcagagttta agtttattgc aggtgtcggt ccaaacaatt ttacagatat
     6001 atcagcaacg aacgtttacc aagatagggt tgcgattgat ggtctaaact tatttgaatt
     6061 taaatataaa ctcaaaccgt tttttaatcc tgaaaatgta tatagtaaac aagatagaca
     6121 attctttaaa ggtaatcggg attatgaaga atagttaaat ttaataaaaa gatagaaaga
     6181 aaataacttt acataataag gcaaggacaa tatgtgcaag aagtacaact tcaatataaa
     6241 aatcttggtt aagcattttt ataggcacaa atgtcttgcc tttttctttt gtaaaaattt
     6301 aaaaacaata caccgaattt tctgaaaaag gttgtaatgt attgctaaaa atgataagtt
     6361 attaatcata ttacacttta gtgtggtaga gaagtaaagc gaacaacgaa aataccaagt
     6421 gatattaaat acagtattga aagtaaaggg tggtcgagtg aataattcag aacaattaat
     6481 tgcgttaaaa gaatcggaaa cagcattttt aaaatatttt aataaagcgg attatgagtt
     6541 agttgatttt agtgtggttg aaaagttgga ctggaaacaa ttgaaccatg aggatttgca
     6601 gcagatgggt gagcgaaatt tttggcaaca tgagcatcaa atttatgcac ttcgaaatga
     6661 ttttacagat caattattgc gttattactc aatgtatcca actgcagcaa caaaagtggc
     6721 atacacaggt ttaatcattc ggaataatga agcggctgta caagtgggtt tggaaaacta
     6781 tgcaccatca ttagcgaatg tacaacagag cttaaagcta tttattcagt ttattcaaca
     6841 gcagttgaga gacaacgtgc attttgttgt attgggacat tatcaattgc ttgatgcctt
     6901 gctcgataaa tcgttacaaa caccagacat actatcaatg attgaggaac gtaatttatc
     6961 gggattggtt acatatttgt cgactgaaca tccaatcgtg caaatcttga aagagaatac
     7021 gcaacaacaa ttaaatgtat tggaacacta tattccaaat gaccatccag cactcgttga
     7081 attaaaaata tgggaacgtt ggttacatac acaaggttac aaagacatcc atttagatat
     7141 tactgcgcag ccacctagat cctattacac aggtttattt attcaatgtc attttgctga
     7201 aaatgaatct cgagttttaa caggtggtta ttacaaagga agcatcgaag ggtttggatt
     7261 aggattaaca ctttaagtaa gggagtatgc acaatgttaa gaatcgccat agcaaaaggg
     7321 cgtctaatgg atagtttaat taactattta gatgcaattg aatatacgac attatcagaa
     7381 acattaaaaa atagagaacg ccaattatta ttaagtgtag ataatattga atgcatttta
     7441 gtaaaaggaa gtgacgttcc aatctatgtg gaacaaggaa tggccgacat aggcattgtt
     7501 ggtagcgaca tattagatga gcgccaatat aatgttaata atttgttgaa tatgcctttt
     7561 ggagcatgtc attttgcggt tgcagcgaaa cctgaaacga ccaattatcg taaaatcgca
     7621 acgagttatg tacatactgc tgaaacatat tttaaatcaa aaggtattga tgtcgaattg
     7681 attaaattga atggttctgt tgaattagct tgtgtcgtag atatggtaga cggaattgtc
     7741 gacatcgttc aaacaggtac tacgctaaaa gcgaacggac tggttgaaaa gcaacatatt
     7801 agtgatatca atgcaagatt aataactaat aaagcagctt attttaaaaa atcacaatta
     7861 atagagcaat ttattcgctc tttggaggtg tctattgcca atgcttaatg cacaacaatt
     7921 tttaaatcaa ttttcattag aagcaccatt agatgagtca ttgtatccaa ttattcgcga
     7981 tatttgtcag gaagttaaag ttcatggaga taaggctttg aaaatgtata atctaacatt
     8041 cgatcatacg aaaacagatc atttagaaat tagtcatgaa caaattaaag cagcatttga
     8101 cacattagat gaaaaaacaa aacaagcatt acaacaaagt tatgaaagaa ttaaagcata
     8161 tcaagaaagt attaaacaga cgaatcaaca gttagaagaa tcagtggagt gttatgaaat
     8221 ataccatcca ctagaaagtg tgggtattta tgtgcctggt ggcaaagcaa gttatccatc
     8281 aacggttcta atgacagcga ctttagcaca agtagcaggt gtagaaaata ttgttgttgt
     8341 gacaccacct caacctaacg gagtatccca agaggtatta gctgcatgtt atattacgca
     8401 agttaatcaa gtgtttcaag ttggtggtgc tcaaagtatt gctgcattga cttatggaac
     8461 agaaacgata cctaaagttg ataagattgt aggtccaggt aaccaatttg ttgcatatgc
     8521 caaaaaatat ttatttggac aggtaggtat tgatcaaatt gcaggatcaa cagaaatagc
     8581 actgattatt gacgacacca cagatttaga tgccatcgta tatgatgtat ttgcgcaagc
     8641 agaacatgat gaattagcac gtacatatgt cattagtgaa gatgcgcaag tccttaaaga
     8701 tttagaatca cgtattgcta aagcattgcc taatgtggac agatacgaca ttgtttctaa
     8761 aagtatcgct aatcaacact accttatcca tgctagtaat tttgatgaag catgccatgt
     8821 catgaataca atcgcgcctg aacatgcgtc gattcaaaca gtaaatcctc aaccatatat
     8881 tgaaaaagtg aaatatgtgg gtgcattgtt tattggacat tattcgccag aggtcatagg
     8941 agattacgtt gcaggtccaa gtcatgtatt acctacaaat agaacagcta gatttaccaa
     9001 tgggttatcg gtcaatgatt tcttaacacg gaacacggtc atccatttat caaaagatac
     9061 gtttgaacaa attgctgatt cagcacaaca tattgctcat gttgaagcat tatacaatca
     9121 ccagcagtct attttaatac gtcagtctta ggggagtgta attgaaatga tttatattga
     9181 taaaaatgaa agtccagtta cgccgttgga tgaaaaaaca atgacgtcta ttattagtgc
     9241 aacgccatat aatttatatc ctgatgcagc atatgaacaa ttcaaggaag cttatgctaa
     9301 gttttacgga ttatcgcctg aacaaattat tgcaggaaat ggatctgatg aattgattca
     9361 aaagttaatg ctgatcatgc cagaaggtcc ggctttaacg ctaaatcctg atttttttat
     9421 gtatcaagca tatgcggcac aagtaaatcg tgaaattgca tttgtagatg caggatcaga
     9481 tttaacgttt gatttggaaa ccattttaac gaaaatcgat gaagtacaac catcattttt
     9541 tattatgagt aatccacata acccttcagg caagcaattt gatacggcat ttttaacagc
     9601 tattgcagat aagatgaaag cattaaacgg atactttgtc attgatgaag catatttaga
     9661 ttatggtacg gcatatgacg tggaactggc accacacatc ttaagaatgc gtacattatc
     9721 aaaggcgttt ggaattgccg gcttaagatt aggtgtctta attagtactg ctggaacgat
     9781 aaagcatatt caaaaaatag aacatccata tccattaaat gtatttacgc taaatattgc
     9841 gacttatatt tttagacata gagaagagac aagtcgattt ttaacaatgc aacgacagtt
     9901 agctgagcag ttaaaacaaa tatttgatac acatgttgca gataaaatat cagtattccc
     9961 atcaaatgcc aattttgtac ttactaaagg ttcagcagcg caacaattag gacaatacgt
    10021 atatgaacaa ggatttaaac ctcgttttta tgatgagccg gtgatgaagg gctatgtaag
    10081 atactcaatt gcaaccgaac cacagttaaa ccaattagaa gaaattgtta aagaatggag
    10141 cgcaaaatat gatttatcaa aaacaacgaa acacagctga aacacaacta aatatttcaa
    10201 tatcagatga ccagtcacca tcgcatatta atacaggtgt gggcttttta aatcatatgt
    10261 taacattgtt tacatttcat agcggtctgt cattaaacat tgaggcacaa ggtgatatcg
    10321 atgtagatga tcaccatgta actgaagata tcggcattgt tattggccaa ttgttacttg
    10381 aaatgattaa agataaaaag catttcgttc gttatggagc gatgtacatt ccaatggatg
    10441 aaacattagc acgtgtcgtt gtggatataa gtgggcgtcc atacttatct ttcaatgcat
    10501 cattaagtaa agaaaaagtt ggcacgtttg atacggagtt agtagaagaa ttttttagag
    10561 cagtcgtaat caatgcaaga ttaacaacgc atattgattt aattcgtgga ggtaatacac
    10621 accatgaaat tgaagctata ttcaaagcgt tttcccgttc attaggcata gcgctaactg
    10681 caactgatga tcagcgtgtg ccgtcatcga aaggtgtgat tgaatgattg tcatcgttga
    10741 ttatggatta gggaatatta gtaatgtaaa acgcgctatt gaacatttgg ggtatgaggt
    10801 ggttgtctca aataaccaaa atataattga tcaagcagaa acaatcatat tgcccggtgt
    10861 cggccatttt aaagatgcga tgtcagagat aaaacgatta aatctcgatg caatattggc
    10921 taagaatact gataagaaaa tgatcggtat ttgtctagga atgcagttaa tgtatgagta
    10981 tagtgatgaa ggcgatgcat ctggattagg gtttatccca ggaaatattt cgcgtatcca
    11041 aacagaatac ccagtgccgc acttaggttg gaataattta gtgagtaagc atcctatgtt
    11101 aaatcaagat gtttacttcg tacattctta ccaagcgccg atgtcagaaa atgtcattgc
    11161 atatgcgcag tatggtactg atattccagc tattgtccaa tttaacaatt atattggtat
    11221 tcaattccat cctgaaaaaa gcggtacata tgggttacaa attttgcgtc aggcaataca
    11281 agggggattt ataaatgatt gaattatggc cagcgattga tttgattggg tcaacaagtg
    11341 tgaggttaac agagggtaaa tatgatagtg aagaaaaaat gtcgcgttcg gctgaagaaa
    11401 gtattgctta ctatagtcga tttgaatgtg tgaatcgtat tcatattgtc gacttgatag
    11461 gtgctaaggc acagcatgcc cgagagtttg attatattaa gtcattgagg agattaacaa
    11521 cgaaagatat tgaagtaggt ggtggcattc gcacgaagtc acaaatcatg gactactttg
    11581 ccgcaggaat taattattgc atagttggaa cgaaaggtat tcaagatact gattggctta
    11641 aagagatggc acatacattt ccaggtcgca tttatttatc tgttgatgct tatggagaag
    11701 atattaaagt gaacggatgg gaagaggaca cagagttaaa tttatttagt tttgtgagac
    11761 ggttatcgga tatacctctt ggcggcatta tatatactga tattgctaaa gatggcaaaa
    11821 tgtccggacc taactttgaa ttaactggtc aattagtaaa ggcaacgacg attcctgtca
    11881 ttgcttccgg tggtattaga catcagcaag atattcaacg attagcgtcg ctaaatgttc
    11941 acgctgccat tataggaaag gctgcacatc aagcatcttt ttgggagggg ctaaaatgat
    12001 taaaaaacgt atcattccat gtttagatgt caaagatggt cgtgtcgtta aagggattca
    12061 atttaaagga ttaagggata ttgggaatcc tgttgattta gcaatgtatt acaatgaagc
    12121 gggtgctgat gaattagtat ttttagacat ctctaagacg gaagagggtc atagcttaat
    12181 gctagaagtg attgaacaga cagcgtcacg cttgtttatc cctcttactg tagggggtgg
    12241 gattcaaagt ctcgatgata ttacccaatt gttaaatcat ggtgcagata aagtatcatt
    12301 aaattcaagt gctttaaaaa atccacagct cattaaacaa gcgagtgata aattcggtag
    12361 acaatgcatc tgcatagcaa ttgatagcta ttatgatcct gaaagaaaag cacattattg
    12421 ttgtacgcat ggtggtaaaa agatgacaaa tattaaagta tatgactggg tacagcaagt
    12481 agaacagtta ggtgcaggtg agctcctcgt tacaagtatg ggacatgatg gtatgaaaca
    12541 aggctttgat attgagcatc ttgcaaaaat aaaatccctt gtaaatattc caatcattgc
    12601 ttctggtggt ggtggcaatg cacaacactt tgtagaatta tttgatcaga cggatgtttc
    12661 tgcaggttta gctgcaagta tattacatga tcgagaaacg acggttcaat ctattaaaga
    12721 agtgatacgg caaggaggta tagcagtaag atgaccaatt acaaaattga ttttagcaaa
    12781 ggtttagtgc cagcaatttt acaagataat caaacaaaac aagtattgat gttaggttat
    12841 atgaatcaag aagcttttga taaaacgata gaagatggtg tagtatgttt ctattcgcgg
    12901 tcgaaacaac gtctatggac aaaaggtgaa acatctggtc atacgcaact tgttaaagat
    12961 attcatgtag attgcgacaa tgatactatt ttaattgatg tcataccaaa tggaccaaca
    13021 tgtcatacag gcagtcaaag ttgtttcaac acagaagttc cattttcagt gcaaacatta
    13081 gcgcagacag ttcaagatag tgcccaatcc aataatgaaa agtcatatac aaaatattta
    13141 ttaacagaag gtatagaaaa gattacgaaa aaatatggtg aagaagcttt tgaagtcgta
    13201 attgaagcaa ttaaaggtga caaaaaagca tttgtaagtg aagtagcaga tgaactttat
    13261 catttatttg tcttgatgca tgcgctaggc gtcgattttt cagaaattga ggcagaatta
    13321 gcgcgtagac atcataagcg caataacttt aaaggcgaac gacaaaatat cgaacagtgg
    13381 taaaacaagt atgggctgag atatagagaa aaggatcatg tcttatacac ttacaaatat
    13441 tgtggaaaac gtgacatttt caagtttaaa atacgacacc aacatatttt aactatgaat
    13501 gcggtactaa agttgcgaac gcgttataga taagtagtgg ataatcacaa tacgaaacca
    13561 aaaataattt gaaaagtaaa ttgagcaact caggaataga tgtcactgtt aaagatgttg
    13621 aaaagtatat gaatcgatat aatgaagtta tgaagggaaa aaatggcgaa aaagctaaaa
    13681 agttatattt gtcgttacta cctattaata tcatagttgt ctttatattc tttgtattta
    13741 tactgtgaat aaaaatatat ctagcctgaa atagaaatgt catagcctat ttaaaagaca
    13801 atctccatta gaactaagat gtgcatcccg aaagttggac taaacaacta actttatggg
    13861 atgtattttt atgcaaatca tcataaattc gagattaagt taaagttagt tcaagagtaa
    13921 ttaaacaata aattaaaaat agtaggatac ttactttgag ggaagaaaat taactgtata
    13981 tatttagttt aggaacaagt attacggttt atcctgatac aattattgtg gatgggatga
    14041 tatttttagg tttaaaatac gacaccagca aacatcataa ctgtgatagc tcataaatct
    14101 ccacatatag ctaatctaaa aaaataatac atcattggaa tcaagcccca agcatgtaaa
    14161 tattaaaaat cacaaaagat atatgtaaaa aagttacaat ttgcataatt aaattgtgtc
    14221 taattattga ctaattaaat tttgccaaat ataatattaa ttaataattt gaaatgatta
    14281 gcgtatacac tttaaattct ctttggagaa tatatttttt aaatacaaat gtaaacgctt
    14341 tctcgtcaaa ttaaacaata gaaaggatgg tcattatgag tgcttggtta agtaaattat
    14401 ttgagtttat tcctcgaata attatcaatt tgtttatcta aaataaaaaa atagaggtgc
    14461 tgacaatgat gaaaagtcaa aataagtata gtattcgtaa atttagtgta ggtgcatctt
    14521 ccattttaat agctacatta ctatttttaa gtggtggaca agcacaagca gctgagaagc
    14581 aagtgaatat gggaaattca caggaggata cagttacagc acaatctatt ggggatcaac
    14641 aaactaggga aaatgctaat tatcaacgtg aaaacggtgt tgacgaacag caacatactg
    14701 aaaatttaac taagaacttg cataatgata aaacaatatc agaagaaaat catcgtaaaa
    14761 cagatgattt gaataaagat caactaaagg atgataaaaa atcatcgcgt aataataaaa
    14821 atattcaacg agatacaaca aaaaataaca atgctaatcc tagcgatgta aatcaagggt
    14881 tagaacaggc tattaatgat ggcaaacaaa gtaaagtggc gtcacagcaa cagtcaaaag
    14941 aggcagataa tagtcaagat tcaaacgcta ataacaatct accttcacaa agtcgaacaa
    15001 aggaagcacc atcattaaat aagttagatc aaacaagtca acgagaaatt gttaatgaga
    15061 cagaaataga gaaagtacaa ccacaacaaa ataatcaagc gaatgataaa attactaact
    15121 acaattttaa caatgaacaa gaagtgaaac ctcaaaaaga cgaaaaaaca ctatcagttt
    15181 cagatttaaa aaacaatcaa aaatcaccag tagaaccaac aaaggacaat gacaagaaaa
    15241 atggattaaa tttattaaaa agtagtgcag tagcaacgtt accaaacaaa gggacaaagg
    15301 aacttactgc aaaagcgaaa gatgatcaaa cgaataaagt tgccaaacaa gggcagtata
    15361 aaaatcaaga ccctatcgtg ttagtgcatg gtttcaatgg atttacagat gatattaatc
    15421 cttcagtgtt agctcattat tggggcggta ataaaatgaa cattcgccaa gatttagaag
    15481 aaaatggtta caaagcttat gaagcaagta taagtgcttt tggaagtaac tatgaccgcg
    15541 cagttgaact ttattattat atcaaaggcg gtcgtgtaga ttatggtgca gcacatgcag
    15601 caaaatatgg acatgaacgt tatggaaaaa catacgaagg aatttacaaa gactggaaac
    15661 caggacagaa ggtacaccta gttggacata gtatgggtgg tcaaacgata cgtcaactag
    15721 aagaattact gcgtaatggt agtcgtgaag aaatagagta tcaaaagaaa catggtggcg
    15781 aaatttctcc actattcaaa ggtaataatg acaatatgat ttcatcaatt actactttag
    15841 gaacgccaca taatggaacg catgcttcag atttagctgg taatgaagct ttagtgagac
    15901 aaattgtatt tgatatcggt aaaatgtttg gtaataaaaa ctctagagta gacttcgggt
    15961 tggctcaatg gggtctaaaa cagaagccaa atgaatcata cattgattat gtcaaacgcg
    16021 ttaaacaatc taatttatgg aaatcaaaag ataatggatt ttacgatctg acgcgtgagg
    16081 gtgcaacaga tttaaatcgt aaaacgtcgt tgaaccctaa cattgtgtat aaaacataca
    16141 ctggtgaagc aacgcacaaa gcattaaata gcgatagaca aaaagcagac ttaaatatgt
    16201 ttttcccatt tgtgattact ggtaacttaa tcggtaaagc tactgaaaaa gaatggcgag
    16261 aaaacgatgg tttagtatcc gttatttctt ctcagcatcc atttaatcaa gcttatacaa
    16321 atgcgacgga taaaattcaa aaaggcattt ggcaagtaac gcctacaaaa catgattggg
    16381 atcatgttga ttttgtcgga caagatagtt ctgatacagt gcgcacaaga gaagaattac
    16441 aagatttttg gcatcattta gcagacgatt tagtgaaaac tgaaaaggtg actgatacta
    16501 agcaagcata agttaaaaag taaagggagg aattaacaat gactgcagac ttctttcaat
    16561 taatcggatc attatttaga attctaaaag aattattcaa gtaaaacctt ggcggggccc
    16621 caacaaagag aaattggatt cccgatttct acagacaatg caagttggcg gggccccaac
    16681 ataaagaatt tcgaaaagaa attctacaaa caatgcaagt tggggtggga cgacgaaata
    16741 aattttgcga aaatatcatt tctgccccac tcccattggc atttacgaag tttaaatgtg
    16801 caattagaat atatgtataa caatattaaa cacgcggtaa aacgaagtca gtcaattcaa
    16861 actgatttcg cccaccgcgt gtttttaaca tagcttaatg attaataagc attaatgttc
    16921 aatttatatg gttgttttcc aataataaac ctaaagatat agaattcacg caatatcata
    16981 ccgacaccta tacataatcc taaaatgaat agtagtgata tcgctagaaa gaccattgta
    17041 ttatcctcaa atatatttgt atatgcaaac aatgagtcta gaatgattgg atgtaataaa
    17101 taaataaaga atgagaaagc actaatcatt tgaatcgtat taaataacat tgttttaaaa
    17161 tgcgtgcaaa tacccaagat aacaataaac ataatactat tatatggtgt taatgaatat
    17221 gaaaagctgg taacattcca atagtctcca tttgctaacg caataaacac aaaataagta
    17281 gctacagcta atacaatcat aataactaaa taacgttcta agaaatttaa aacacgttcg
    17341 tagttataac ccatatatgc acctaagaag aaataaaaaa tccatccgaa tattatagtg
    17401 ttttcactta atggataata gtgtagcacg gtatcgtgaa acgctgtgtt gttcgtaaag
    17461 taatataaaa atgattgctg taaaataaaa gataacaata ataatatttt actattgaat
    17521 aggttatagt taattttaaa aatgatataa ctcaaaataa agaattgcat gataacaacg
    17581 ataaaatagc cataccattg acctaatagg acattttcaa tgaattgttt attgaaactt
    17641 gaatctgtta ataatgattc actataactg taaaacaatc ccattaatat gtaaggaata
    17701 agtatatatt ttacgcgtgt agttaagtat ctataggtga ctttttgata gtttaaagtc
    17761 gtcaataact gcgacaaaat aataaaacat ggtgtaccaa aaatgacaat attacgaata
    17821 tagaactgta gtactaaaga tcctccttcc atattctcat gttttaaagt aatttgtgtt
    17881 aataaatgtg taacaataat aattgcacat ataatagcac gtaaatatac gagttcaagt
    17941 ctaatctttt tcatggaatc cgtcccatct cttaattaaa tgctcaaaag catcatcact
    18001 aattagtatt ctagggatgt aataatcatt ggagttcgga gtgactgctt tttcctctaa
    18061 tgaaaaaccg tattttaacc cagctttttt gattactggt aatttatcgt cattcatcaa
    18121 gccataagga taggctatag ttttctgcga ctttttaaag tttttagtta gatatttttc
    18181 acttttgttt aaatctttta tgattgtagc ttcagaagat ttcattaatt ttgacttatt
    18241 atttttagat aagttatgca aatcgtgggt atgtgtttca aattcccata acccagtttt
    18301 atacatttct tttagttctt ttttactaat catatcgagg ttgtgaaagt tttcttcccc
    18361 aacatgacct gtgataataa acccagttgc cggtatttta tattttttta agattggata
    18421 agcattttca taaatagttt catccatatc atcaaagtta atccatacac ttcgttttgg
    18481 aaacttacct tttttcttgt aatataaaaa ttctttcaag gttaaaaatt tagcatcatg
    18541 tgattttagc cattttattt gagattcaaa ttgtgattga ctaacactat aatttttaat
    18601 ttctttacta ctagaaaaga aataaataaa attattcaga aaattcgctt ttcttacacg
    18661 gtgataattt aatgccagag cactattttc tttatatttc agttttttag gtgaatcgtc
    18721 atctgcattt gcaatatgat gaccatccag tgtgcttaca ggcaatatga tcaagatact
    18781 caacactaaa attattaatt ttctatactt cacgattctc ttcctctctg ccatttttga
    18841 atcaatatgc taattgtaaa aaatacaaaa atgataatcg cgaaaatgcc catagtttca
    18901 aatatatcta aaatttcagt attttcaatg tttaaagcaa cacgtattgt attgatactt
    18961 tcgtcatgaa tttcaaatat agtaccaata taaacgagta gaacaactaa acaatatatc
    19021 caaaagacac acgatatagc gataagtgct gtttctctta caatatttag cgatgatttt
    19081 agcgttgggt attccctctg tctgggcttg accatgttgc gtaaccacct ttcttacgtt
    19141 ttaatgcttt tggaaatgcg acaagaacta ctgctgcgtt aataatccag tatactgtcg
    19201 gataccaact tacaaatatg agtccagcca tattcttttt ctcgtagcga ctatcaataa
    19261 agagtgcgac tgtaaattga ataacgttta taaaagtcat agtaaatgat gatagtagaa
    19321 atattgaaaa actatatgtc ataaatgtat agtctaagaa gtttgctgtt atgaacaaat
    19381 agcctaaata tagaagcact atatataccc ataaaattga gatgatttgc tcaaacatca
    19441 aaatatataa aggaaacctt ttcgttttca ttgtgctaaa aaagtctcgt agtaatactt
    19501 cgtgtccccc ttgagcccat ctcacgcgtt gcttccaaag acctcccaat gtttctggaa
    19561 ccaacatcca acacatggca agcggttcat acttaatacg atatccacgt aaatgcaatt
    19621 tccaagaaac tgcaatatct tcggtaatca tatcagtatc ccagtagcca acgtcgacaa
    19681 ctgcactttt tttaaataga gtgaagacac ccgaaatagt attgactgcg ccagcaagtg
    19741 tctgacttcg cttaatacag ccaattaaac ttgcatattc tatcgtttga attttaccta
    19801 aaatagaact cttatttcga attctaggat tacctgtaac tgcaccaagt tttggatcat
    19861 gtttgaaatt ctcaatcata taatatggtg catcttgatc aacgatagta tctgcatcca
    19921 agcacattac ataatcatat gaagcctgtt taatgccttg attgagtgcg ttggctttac
    19981 ctctgttttc ttgtaaatcg acgaaaataa agtcattatt ttctttgatt ttatagatga
    20041 gttctgctgt attatctgaa cttccatcat taatgataat aatttctttt ttctcgtatt
    20101 tgagtgcaag aacattagac aacgtatctt caatcgtttc actttcgtta taacaggcaa
    20161 gtaaaaatgt aatgccttct aattcatcca catttatgtc aggcttcttg ttcaatgaat
    20221 atctaatttc tctggtaaaa tagaaataaa ttgaaccgac aatccagtaa atagacataa
    20281 atacaggata aaaaagcaaa aagttaaaaa attgcaattt ctttacctac ctttcgttag
    20341 ttaggttgta agccatatgg taattgatag tattttaatt tgcaatagat tgttgttata
    20401 attaaacgga aatatttgta attgcaactt aattttcctg taacatagtg tgattaattt
    20461 tcagtagggg ggttttaaaa attgaaggat aagattattg ataacgcaat aaccttattt
    20521 tcagagaagg ggtatgacgg tacaacactt gatgatatag ctaaaagtgt aaatataaaa
    20581 aaagcgagct tatattacca ttttgactcg aaaaaaagta tttacgaaca aagtgttaaa
    20641 tgttgttttg attaccttaa taatattatt atgatgaatc aaaataaatc gaactattca
    20701 attgatgctt tatatcaatt cttatttgag tttattttcg acatcgaaga aaggtatatt
    20761 agaatgtacg ttcaattatc taatacgcct gaggaatttt ctggaaatat ttacggacaa
    20821 atacaagatt taaatcaatc attaagtaaa gagatagcaa aattctatga tgaatcaaag
    20881 ataaagatga caaaagaaga ctttcagaat ttaatattgc tgtttcttga aagttggtat
    20941 ttgaaagcat ctttttcgca aaaatttgga gcagtggaag aaagtaaaag tcaattcaaa
    21001 gatgaagtgt attcgctact aaatatattt ttgaagaaat aatttttgtt actagtttgt
    21061 aataattaac ttacttttgt aaaaaaagac atgagattat ttttt
//
LOCUS       DAPSKH010000051        20864 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPSKH010000051 DAPSKH010000000
VERSION     DAPSKH010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 20864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20864
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.051"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            118..1293
                     /locus_tag="RPH49_001989"
     CDS             118..1293
                     /locus_tag="RPH49_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diglucosyl diacylglycerol synthase"
                     /protein_id="HDY5125118.1"
                     /translation="MVTQNKKILIITGSFGNGHMQVTQSIVNQLNDMNLDHLSVIEHD
                     LFMEAHPILTSICKKWYINSFKYFRNMYKGFYYSRPDKLDKCFYKYYGLNKLINLLIK
                     EKPDLILLTFPTPVMSVLTEQFNINIPVATVMTDYRLHKNWITPYSTRYYVATKETKQ
                     DFIDVGIDPSTVKVTGIPIDNKFETPINQKQWLIDNNLDPDKQTILMSAGAFGVSKGF
                     DTMITDILAKSANAQVVMICGKSKELKRSLIAKFKSNENVLILGYTKHMNEWMASSQL
                     MITKPGGITITEGFARCIPMIFLNPAPGQELENALYFEEKGFGKIADTPEEAIKIVAS
                     LTNGNEQLTNMISTMEQDKIKYATQTICRDLLDLIGHSSQPQEIYGKVPLYARFFVK"
     gene            1271..2461
                     /locus_tag="RPH49_001990"
     CDS             1271..2461
                     /locus_tag="RPH49_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125119.1"
                     /translation="MQDSSLNNYANHKNFILMLIILFLMEFARGMYILSYINFLPTVT
                     SIAVAITSLAFSIHFIADASTNFVIGFLLKKFGTKIVLTTGFILAFTSLFLVIWFPAS
                     PFVIIFSAMMLGIAVSPIWVIMLSSVEEDKRGKQMGYVYFSWLLGLLVGMVFMNLLIK
                     VHPTRFAFMMSLVVLIAWILYYFVDVKLTNYNTRPVKAQLRQIVDVTKRHLLLFPGIL
                     LQGAAIAALVPILPTYATKVINVSTIEYTVAIIIGGIGCAVSMLFLSKLIDNRSRNFM
                     YGVILSGFILYMILIFTLSMIVNIHIVWIIALAIGLMYGILLPAWNTFMARFIKSDEQ
                     EETWGVFNSIQGFGSMIGPLFGGLITQFTNNLNNTFYFSALIFLVLAVFYGSYFIANR
                     EKAK"
     gene            complement(2574..3083)
                     /locus_tag="RPH49_001991"
     CDS             complement(2574..3083)
                     /locus_tag="RPH49_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcG family protein"
                     /protein_id="HDY5125120.1"
                     /translation="MILGLALIPSKSFQEAVDSYRKRYDKQYSRIKPHVTIKAPFEIE
                     DGDLDSVIEQVRARINGIPAVEVHATKASSFKPTNNVIYFKVAKTDDLEELFNRFNGE
                     DFYGEAEHVFVPHFTIAQGLSSQEFEDIFGQVALAGVDHKEIIDELTLLRFDDDEDKW
                     KVIETFKLA"
     gene            complement(3277..4035)
                     /locus_tag="RPH49_001992"
     CDS             complement(3277..4035)
                     /locus_tag="RPH49_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDY5125121.1"
                     /translation="MSEFKTGKINKHVLYSNILNRDVTISIYLPESYNQLVKYNVILC
                     FDGLDFLRFGRIQRTYESLIKEARIDDAIIVGFHYEDVDKRREEFHPQGSRSHLTIQS
                     VGKEILPFIDSTFSTLKVGNARLLVGDSLAGSIALLTALTYPTIFSRVAMLSPHSDDK
                     VLDKLNQCANKEQLTIWHVIGLDEKDFTLPTNGKRADFLTPNRELAEQIKKYNITYYY
                     DEFEGGHQWKDWKPLLSDILLYFLRKNTDDQHYE"
     gene            complement(4180..5748)
                     /locus_tag="RPH49_001993"
     CDS             complement(4180..5748)
                     /locus_tag="RPH49_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine:cation symporter family protein"
                     /protein_id="HDY5125122.1"
                     /translation="MIEKLVTFLNEVVWSKPLVYGLLITGVLFTLRMRFFQVRHFKEM
                     IRLMFQGEKSPNGISSFQAIAMSLAGRVGTGNIVGVSTAIFIGGPGAVFWMWITAFLG
                     ASSAFIESTLGQIFKRVENNEYRGGPAYYIEYGIGGKFGKIYGIIFAIVTIISVGLLL
                     PGVQSNAIASSMHNAIHVPQWLMGAIVVVILGLIIFGGVRSIANVATAVVPFMAIIYI
                     LMAVIIICINIQEVPALFALIFKSAFGLQSAFGGIVGAMIEIGVKRGLYSNEAGQGTG
                     PHAAAAAEVSHPSKQGLVQAFSVYIDTLFVCTATALIILISGTYNVTDGTVNANGTPH
                     LIKDGGIYVENATGKDYSGTAMYAQAGIDKAFHGSGYQFDPTFSGVGSYFIAFALFFF
                     AFTTILSYYYITETNVAYLTRNQNNQVSSIFINIARVIILFATFYGAVKTADVAWAFG
                     DLGVGLMAWLNIIAIWILHKPAVNALKDYEIQKKRLGNGYNAVYQPDPNKLPNAVFWL
                     KTYPERLKQARAKK"
     gene            6090..7175
                     /locus_tag="RPH49_001994"
     CDS             6090..7175
                     /locus_tag="RPH49_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDY5125123.1"
                     /translation="MLNKVWFRTGIALIMLFILIKLFMEVHEVFTPIATIIGSVFLPF
                     LISGFLFYICLPFQNLLEKVGFPRWASITTIMLALFAIIGLIVAFVAPIIISNINNLI
                     SQTPALQKEAEQIIKFALAQMDKLPEDVTSRITNMVKSMGDGVTNILSNSLQYITSLI
                     STIFLLIMVPFFLIYMLKDHEKFIPAVAKFFKGERKVFFVDLLTDLNFTLKSYIQGQV
                     TVSVILGIFLYIGYSIIDLPYIPLLVLFAGVANLIPFLGSWLSFAPAAILGIIDSPTT
                     FIWVCIITLIAHQLEGNIITPNVMGKSLSIHPLTIIVVILAAGDLGGFTLVLIAVPLY
                     AVLKTVVSNIFKYRQRIIDKANSNVKD"
     gene            complement(7372..8142)
                     /gene="fabI"
                     /locus_tag="RPH49_001995"
     CDS             complement(7372..8142)
                     /gene="fabI"
                     /locus_tag="RPH49_001995"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDY5125124.1"
                     /translation="MLNLENKTYVIMGIANKRSIAFGVAKVLDQLGAKLVFTYRKERS
                     RKELEKLLEQLNQPEAHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFANMEDL
                     RGRFSETSREGFLLAQDISSYSLTIVAHEAKKLMPEGGSIVATTYLGGEFAVQNYNVM
                     GVAKASLEANVKYLALDLGPDNIRVNAISAGPIRTLSAKGVGGFNTILKEIEERAPLK
                     RNVDQVEVGKTAAYLLSDLSSGVTGENIHVDSGFHAIK"
     gene            complement(8420..10264)
                     /locus_tag="RPH49_001996"
     CDS             complement(8420..10264)
                     /locus_tag="RPH49_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monovalent cation:proton antiporter family
                     protein"
                     /protein_id="HDY5125125.1"
                     /translation="MEFLSLVIVVLAAFLTPIIVNRLNINFLPVVVAEILMGIVIGNS
                     FLNIVERDSILNILSTLGFIFLMFLSGLEIDFKAFKKDKRARQGQNDDESSIPGHLNL
                     ALTVFAFIMIISILLAYVFKWLGLVDDVLLMVIIISTISLGVVVPTLKEMNIMRTTIG
                     QFILLVAVLADLVTMILLTVYGAINGQGGSTIWLIGILVVFTAISYILGVQFKRMSFL
                     QKLMDGTTQIGIRAVFALIILLVALAEGVGAENILGAFLAGVVVSLLNPDEEMVEKLD
                     SFGYGFFIPIFFIMVGVDLNIPSLIKEPKLLIIIPILIVAFIISKLIPVMFIRRWFDM
                     KTTIASAFLLTSTLSLVIAAAKISERLNAISAETSGILILSAVITCVFVPIIFKKLFP
                     VPDEFNRKIDVSLIGKNQLTIPIAQNLTSQLYDVTLYYRKDLSDRRQLSDDITMIEIA
                     DYEQDVLERLGLFDRDIVVCATNDDDINRKVAKLAKAHQVERVICRLESTTDDTELVD
                     SGIEIFSSYLSNKILLKGLIETPNMLNLLSNVETSLYEIQMLNYKYENIQLRNFPFGG
                     DIIFVRIIRNNESIVPHGDTQLRYGDRLIVTGAKEYVDELKQELEFYF"
     gene            complement(10274..11659)
                     /gene="mgtE"
                     /locus_tag="RPH49_001997"
     CDS             complement(10274..11659)
                     /gene="mgtE"
                     /locus_tag="RPH49_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDY5125126.1"
                     /translation="MSMNTDEKERVQEELYDQTLLDQYLENDDIDQFRDEFLALHTYE
                     QSEYFEDTTDENRQKIFQYLSPEEVANFFDQLDIDDDEYELLFDKMNATYASHILEEM
                     SYDNAVDILNELTKPKVASLLTLMNKDDANEIKALLHYDEDTAGGIMTTEYLSLKAHT
                     PVKEALLLVKAQAPDAETIYVIFVVDDDGKLVGVLSLRDLIVAENDAYIEDIMNERVI
                     SVNVADDQEDVAQVMRDYDFMAVPVIDYQEHLLGIITIDDILDVMDEEASEDYSRLAG
                     VSDIDSTNDSIIKTALKRLPWLIILTFLGMITATILGRFEKTLENVALLAAFIPIISG
                     MSGNSGTQSLAVSVRNITTGEINEQSKFRIALREAGSGVLSGVVCSTILFTIIVAIYH
                     QPLLALIVAGSLTCAMTVGTFVGSMIPLLMNKLNIDPAVASGPFITTINDIISMLIYF
                     GLATSFMAYLI"
     gene            complement(11680..12534)
                     /locus_tag="RPH49_001998"
     CDS             complement(11680..12534)
                     /locus_tag="RPH49_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDY5125127.1"
                     /translation="MKFKYHISQQETVKTFLARHDFSKKTVSAIKNNGALIVNDEPVT
                     VRKQLMPNDILEIHLPREIPSVNLIPYARKLEVLYEDAFIIIVTKPNNQNCTPSREHP
                     HESLIEQVLYHCQEHGENINPHIVTRLDRNTTGIVIFAKYGHIHHLFSKVNLKKIYTC
                     LVYGKTHTSGIIEANIRRSKDSIITREVASDGKYAKTSYEVINQNDKYSLCKVHLHTG
                     RTHQIRVHFQHIGHPIVGDSLYDGFHDKIHGQVLQCTQIYFVHPINKNNIYITIDYKQ
                     LLKLFNQL"
     gene            complement(12531..13340)
                     /locus_tag="RPH49_001999"
     CDS             complement(12531..13340)
                     /locus_tag="RPH49_001999"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDY5125128.1"
                     /translation="MRYTILTKGDSKSNALKHKMMNYMKDFRMIEDSENPEIVISVGG
                     DGTLLQAFHQYSHMLSKVAFVGVHTGHLGFYADWLPHEVEKLIIEINNSEFQVIEYPL
                     LEIIMRYNDNGYETRYLALNEATMKTENGSTLVVDVNLRGKHFERFRGDGLCVSTPSG
                     STAYNKALGGALIHPSLEAMQITEIASINNRVFRTVGSPLVLPKHHTCLISPVNHDTI
                     RMTIDHVSIKHKNVNSIQYRVANEKVRFARFRPFPFWKRVHDSFISSDEER"
     gene            complement(13357..13992)
                     /locus_tag="RPH49_002000"
     CDS             complement(13357..13992)
                     /locus_tag="RPH49_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDY5125129.1"
                     /translation="MNQWDQFLTPYKQAVDELKVKLKGMRKQYEVGEQASPIEFVTGR
                     VKPIASIIDKANKRQIPFDRLREEMYDIAGLRMMCQFVEDIDVVVNILRQRKDFKVIE
                     ERDYIRNTKESGYRSYHVIIEYPIETLQGQKFILAEIQIRTLAMNFWATIEHTLRYKY
                     DGAYPDEIQHRLERAAEAAYLLDEEMSEIKDEIQEAQKYYTQKRSKKHEND"
     gene            complement(14009..14356)
                     /locus_tag="RPH49_002001"
     CDS             complement(14009..14356)
                     /locus_tag="RPH49_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125130.1"
                     /translation="MRLYINEIKIKDDILYCYTEDSIKGLSEVGQMLVDSDNYAFAYT
                     LDDGKAYAYLIFVQETWTMLHENMTKKIIINDELELTEFHQELTYILDNIKGNNNYGK
                     EFVATVEETFDIE"
     gene            14542..15135
                     /locus_tag="RPH49_002002"
     CDS             14542..15135
                     /locus_tag="RPH49_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDY5125131.1"
                     /translation="MATNHEIEFKQMITASIYNKLQEKYFKDSVLFKQVNYYIDTPDF
                     KLKEHRSALRIRVKDNQYEMTLKTPAKVGLLEYNYIVDIKPEMNLIISNDNLPDDIRQ
                     IIVEQFGVKDTTLSILGALTTYRQETKYKGDLLVLDKSEYFDTTDYELEFEVKDYNQG
                     LQKFQSLLNELNLEHHQPLNKVQRFFKKKETLSNNIN"
     gene            15239..15604
                     /locus_tag="RPH49_002003"
     CDS             15239..15604
                     /locus_tag="RPH49_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="truncated hemoglobin"
                     /protein_id="HDY5125132.1"
                     /translation="MTTTPYDIIGKEALYDMIDYFYTLVEKDERLNHLFPGDFAETSR
                     KQKQFLTQFLGGPNIYTEEHGHPMLRKRHMDFTITEFERDAWLENMQTAINRAAFPQG
                     VGDYLFERLRLTANHMVNS"
     gene            15627..16433
                     /gene="yjbH"
                     /locus_tag="RPH49_002004"
     CDS             15627..16433
                     /gene="yjbH"
                     /locus_tag="RPH49_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease adaptor protein YjbH"
                     /protein_id="HDY5125133.1"
                     /translation="MAGELRIMENKSREDINLSPVSKIEIYSFFDPFSSDCFKLSAIL
                     SKLRIEYNQYIRIRHILNPSLKVLTKCQAQSTSNFDNIALAYKAAELQGRVRAERFIH
                     LMQNEIIPKRDIITESMICDCIQNAGIDLEVFKDDLQKSKLTESLKIDLHIAREMEIE
                     QAPSLVFFSEDVHEEGLKVEGLYPYHIYTYIINELMGKPIEKNLPPKLETYIQQQQLV
                     TMEELLTIYEWPEKLLNKELKKLAIQQKIEKLKYPDGDFWKSKMPKIKSK"
     gene            complement(16893..18701)
                     /gene="pepF"
                     /locus_tag="RPH49_002005"
     CDS             complement(16893..18701)
                     /gene="pepF"
                     /locus_tag="RPH49_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDY5125134.1"
                     /translation="MSQQLSREEQERKYPEYTWDLTTIFKDDEAFEAAFKEVENELGK
                     EEQFKGHIGDSAETLYNALELEDTLGTKLEKVYVYAHLKQDQDTTNDKYTGMESRAHQ
                     LIIKFSSAWSFLVPEILQIDEDKIQSFVNSYDKLQKFAFDLKLINEKRPHILDAETEK
                     LLTEAQDALSTPSNVYGMFSNADLVFEDAIDKDGNAHPLTQGTFIKYLESDDRKLRES
                     AFRNVYKAYGAHNNTLGATLAGEVKKNVFNARTHNYKTAREKALSNNHIPENVYDNLV
                     KTVHKYLPLLHRYTELRKELLGLDDLKMYDLYTPLIKDIKFEMPYEEAKEWMLKALEP
                     MGEEYLNVVKEGLNNRWVDVYENKGKRSGGYSSGAHLTNPFILLNWSNTISDLYTLVH
                     EFGHSAHSYFSRKFQPSNSSDYTIFVAEVASTCNEALLSDYMDKHLDDEKRLLLLNQE
                     LERFRATLFRQTMFAEFEHKIHAIEEAGEPLTPTRMNEEYAKLNKLYFGDSVETDEDI
                     SKEWSRIPHFYMNYYVYQYATGYSAAQSLSHQILTEGKPAVDRYINEFLKKGSSNYPI
                     EILKNAGVDMTTPEPIEQACEVFEQKLNAFEKLMKA"
     gene            complement(18749..19735)
                     /locus_tag="RPH49_002006"
     CDS             complement(18749..19735)
                     /locus_tag="RPH49_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDY5125135.1"
                     /translation="MLVALNEEKERVLATTVLRKTQYFCPVCGKQVILKRGLKVISHF
                     AHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKVEIEPFLKEIKQIPDILINNKYV
                     IELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFQSLFINPITRKL
                     HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQY
                     IKYCRWQNSVLEPTLSAMYQLQLTDQEVVHNYGYIFPEQIYIENHPIEWQLQVDLLLK
                     NGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDRGNDVQILF"
     gene            complement(19856..20575)
                     /gene="mecA"
                     /locus_tag="RPH49_002007"
     CDS             complement(19856..20575)
                     /gene="mecA"
                     /locus_tag="RPH49_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDY5125136.1"
                     /translation="MRIERVDDTTVKLFITYSDIEARGFSREDLWTNRKRGEEFFWSM
                     MDEINEEEDFVVEGPLWIQVHAFEKGVEVTISKSKNEDMMNMSDDDATDQFDEQVQEL
                     LAQTLEGEDQLEELFEQRTKEKDAQGSKRQKSSARKNTRTIIVKFNDLEDVINYAYHS
                     NPITTEFEDLLYMVDGTYYYAVHFDSHVDQEVINDSYSQLLEFAYPTDRTEVYLNDYA
                     KIIMSHNVTAQVRRYFPETTE"
BASE COUNT         7012 a         3665 c         2915 g         7272 t
ORIGIN      
        1 catctattga ttaaaattgc tataaatgta acgactttgc gtctttattt cttttataat
       61 gccgtaaaat aagttacact taaataaaat tttcaaacta acggagggtg gctattaatg
      121 gttactcaaa ataaaaagat attgattatt actggctcat tcggtaacgg tcatatgcaa
      181 gttacacaga gtatcgttaa tcaacttaat gatatgaatc tagaccattt aagcgtcatt
      241 gagcacgatt tatttatgga agctcatcca attttgactt ctatttgtaa aaaatggtat
      301 atcaatagct ttaaatattt tagaaatatg tacaaagggt tttattacag ccgcccagat
      361 aaactagaca aatgttttta caaatactat ggacttaata agttaattaa tttattgata
      421 aaagaaaagc cagatttaat attattaacg tttcctacac cagttatgtc ggtactaact
      481 gagcaattta acattaatat tccagttgct acagtgatga cagactatcg cttacataaa
      541 aactggatta cgccgtattc aacaagatat tatgtggcaa caaaagaaac gaaacaagac
      601 ttcatagacg taggtattga tccttcaaca gttaaagtga caggtattcc tattgataac
      661 aaatttgaaa cgcctattaa tcaaaagcag tggttaatag acaacaactt agatccagat
      721 aagcaaacta ttttaatgtc agctggtgca tttggtgtat ctaaaggttt tgacacgatg
      781 attactgata tattagcgaa aagtgcaaat gcacaagtag ttatgatttg tggtaagagc
      841 aaagagctaa agcgttcttt aatagctaag tttaaatcta acgagaatgt attgattcta
      901 ggttatacca aacacatgaa tgaatggatg gcatcaagtc aacttatgat tacgaaacct
      961 ggtggtatca caataactga aggtttcgcc cgttgtattc caatgatttt cctaaatcct
     1021 gcacctggtc aagagcttga aaatgccctt tactttgaag aaaaaggttt tggtaaaatc
     1081 gctgatactc cagaagaagc aataaaaatt gtagcaagtt taacgaacgg taatgagcaa
     1141 ttaactaaca tgattagtac aatggaacaa gataaaatta agtatgctac acagacaata
     1201 tgtcgagact tacttgattt aatcggtcat tcatcacaac cacaagagat ttatggaaag
     1261 gttcctttat atgcaagatt cttcgttaaa taattacgct aatcataaaa atttcatttt
     1321 aatgcttatt atcttatttt taatggaatt tgcgagaggc atgtatatcc taagctatat
     1381 taatttcttg ccaacagtta catccattgc tgtagcaata acgtctctag cattttcaat
     1441 acattttatt gctgatgcat ctacaaactt tgttatagga tttttactga aaaaattcgg
     1501 cacaaaaatc gttttaacga ctggatttat tttagcattt acaagtttat ttttagttat
     1561 ttggtttcca gcatcacctt ttgtaatcat atttagtgct atgatgctcg gtattgcagt
     1621 tagtcctatt tgggtcatta tgttatccag tgttgaagaa gataaacgtg gcaaacaaat
     1681 gggctatgtt tatttttcat ggttgttagg cctattggta ggtatggttt ttatgaatct
     1741 acttatcaaa gtgcacccaa cacgctttgc cttcatgatg tctttagtcg ttttaattgc
     1801 atggatatta tattattttg tcgatgtaaa gttaacaaat tataatactc gtccagttaa
     1861 agctcaattg agacaaattg ttgatgtgac aaagcgccat ttattgttgt tccctggtat
     1921 tcttttacaa ggtgccgcaa ttgctgccct agttcctata ttaccaacat atgctactaa
     1981 ggttattaac gtaagcacaa ttgaatatac tgttgcaatc attattggtg gtatcggctg
     2041 tgcagtttcg atgctatttt tatcgaaact aatagataac cgcagcagaa actttatgta
     2101 tggtgttatt ctaagcggat ttattttata catgatatta atttttactc tatctatgat
     2161 tgttaatatt cacatcgtgt ggattatcgc tttagctatc ggtctaatgt atggcatctt
     2221 attaccagca tggaatacct ttatggcacg atttatcaaa tcagatgaac aagaagaaac
     2281 ttggggtgtt tttaatagta tccaaggatt cggctcaatg atagggccat tatttggcgg
     2341 attaattaca caatttacca acaatttaaa caatacattt tatttctcgg cattaatctt
     2401 tttagtctta gctgtatttt atggaagcta ctttatagca aatagagaaa aagctaagta
     2461 aggttaaaac gtattttaaa ataaagaaaa tggtcatttt tattacattc aataaaaatg
     2521 accattttct tattaattca aacatactac gattaacaat actattatgt tacttaagct
     2581 aatttaaacg tttcaataac tttccattta tcttcgtcat cgtcaaaacg taacaaagtt
     2641 aattcatcga taatttcttt atggtctacc ccagctaatg ctacttgacc aaaaatatct
     2701 tcgaattctt ggctagatag tccttgtgct attgtaaagt gtggcacaaa aacatgttca
     2761 gcttctccat agaaatcttc tccattaaag cgattaaaca attcttctaa gtcgtccgtc
     2821 ttcgcaactt taaagtaaat cacattgttc gttggtttga agctagaagc ttttgtagca
     2881 tgaacttcta ctgctggtat accattaata cgagctctaa cctgttcaat gacagaatct
     2941 aaatcaccat cttcaatttc aaatggcgct ttaattgtca catgtggttt aattcgtgaa
     3001 tactgtttat catatctttt acggtaagaa tccaccgctt cttgaaatga ctttgatgga
     3061 attaatgcta atcctaaaat catctgaatt cctcctttgt ttaacctatt gctattatat
     3121 caaatttctt tgaaaaccgt tacattaaaa ataattcatt atacatcttt tgcaatttcg
     3181 acaaatttaa attaaatcaa acagtaaaat cttttataaa ttatattata gaccaaacta
     3241 tatgaagaca attcatacta aatctactaa tgtaaattac tcataatgtt gatcatctgt
     3301 gtttttacgt aaaaaataca ataatatatc tgacagcaat ggtttccaat ctttccattg
     3361 gtgaccacct tcaaattcat cgtaataata agttatatta tatttcttaa tttgttcagc
     3421 taattctcta ttcggtgtta agaaatcggc acgcttacca tttgttggta aagtaaaatc
     3481 tttttcatct agaccaatga catgccaaat tgtcaattgt tctttattag cacattgatt
     3541 tagcttatct aatactttgt catctgaatg tggacttaac attgctacac gactaaaaat
     3601 cgttggatag gtcaacgccg ttaataaggc aatactaccc gctaaactat cccctactaa
     3661 taaccttgca ttacctactt tcagtgtaga aaacgtcgag tcaataaatg gcaatatttc
     3721 tttaccgact gattgaatag ttaaatgaga acgacttcct tgtggatgaa attcctctct
     3781 acgcttatca acgtcttcat aatggaatcc aacaatgatc gcatcatcaa tacgcgcttc
     3841 tttgattaac gattcatatg tacgttgtat tctcccgaaa cgtaaaaaat ctaatccgtc
     3901 aaagcaaaga atgacattat atttaacaag ttgattataa gattctggta aataaatact
     3961 tatcgtgaca tctctattta aaatattact atataaaaca tgtttattaa tcttaccagt
     4021 tttaaattct gacataaaaa agtgccccct agtagttgta ttgttattgt accaagagac
     4081 actatatttt taaaattcaa atttctgagc acctaaaatt atcaatgctg tttctttttt
     4141 tatcaaatga tcactacata tactataaac aaaagtagat tactttttgg cacgtgcttg
     4201 ttttaaacgt tctggatatg tcttcaacca aaagacagca ttaggtaatt tattcggatc
     4261 aggttgataa actgcattat aaccgtttcc taaacgtttc ttttgaattt cataatcttt
     4321 taaagcattt acggcaggct tatgtaaaat ccaaatcgca atgatattta accaagccat
     4381 tagacctaca cctaaatcac cgaatgccca tgctacatca gctgttttaa ctgcaccgta
     4441 aaatgtagcg aacaaaataa tcacacgagc aatattaata aatatcgatg aaacttgatt
     4501 attttgatta cgcgttaaat aagcaacatt tgtttctgta atgtagtagt acgacaaaat
     4561 tgtagtaaat gcaaagaaga ataaagcaaa tgcaataaag tacgaaccta cgccagagaa
     4621 agtaggatca aattgataac cactgccatg gaacgcttta tcaatgccgg cttgtgcata
     4681 catcgcagta cctgaataat ctttacctgt tgcattttca acataaatac cgccatcttt
     4741 aattaaatgc ggtgtgccat tcgcattaac cgtaccatca gtcacattat atgtaccaga
     4801 aataagtata atcagagcag ttgcagtaca tacaaataat gtatcaatat aaactgaaaa
     4861 tgcttgtact agaccttgtt tacttggatg tgatacttct gctgccgctg ctgcgtgtgg
     4921 acctgtacct tgaccagcct catttgagta taatccacgt ttaacaccaa tctctatcat
     4981 tgcgccaacg ataccaccaa aagcagattg taatccaaat gctgatttga aaattaatgc
     5041 aaataacgct ggcacttctt gtatattgat acaaatgata atgacagcca tcagtatgta
     5101 aataattgcc ataaatggta caacggctgt tgcaacattg gcaatactac gtacaccacc
     5161 aaaaataatt aatcccaaaa taactacaac aatagcaccc attaaccatt gtggaacatg
     5221 aatcgcatta tgcatagaac ttgctatagc gttagattgc acaccaggaa gcaatagacc
     5281 tactgagata atcgtaacaa tagcaaagat aattccgtaa attttaccaa atttaccacc
     5341 aataccatat tcaatataat acgctggtcc accacggtat tcattatttt caactctctt
     5401 gaatatttga ccaagtgtag attcaataaa agcactactt gcacctaaaa acgcagtaat
     5461 ccacatccaa aatactgcac caggtcctcc tataaatatt gcagtagata caccgacaat
     5521 attacctgta ccaaccctgc ctgctaaaga catggctatc gcttgaaaac ttgaaatacc
     5581 attaggagac ttctctcctt gaaacattaa tcgaatcatt tctttaaaat gtctaacttg
     5641 aaaaaatcgc atacgcaatg taaatagcac accagtaatt agcaaaccat aaactaatgg
     5701 cttactccaa acaacctcat ttaaaaaggt tactaatttt tcaatcataa gattccccct
     5761 attgtttaaa cataaaaata ttatacgatt aagcacgaga cacttcaata tatttttcag
     5821 aatattctta taaatattaa tatgatcatt tcattattta aacacgttta atattaaaat
     5881 aagttattca tataaactgg tgctgtttga tccaattgca gacttacgag tcattgaaaa
     5941 gtctcacaaa ctattgaaag taaatatctt aaaatagaaa gtgaatggtt aatttaagta
     6001 tatttaaaaa atattaacct ttttaagcac tgctatttag gatatactaa ataataacta
     6061 agtttagaaa aataggagga acatcgttta tgttaaacaa ggtttggttc cgaactggca
     6121 tcgctctgat tatgctgttc attctcatca aactatttat ggaagtgcac gaagtattta
     6181 ctccaatagc tacaatcatc ggttctgtat ttcttccatt tttaattagt ggttttttat
     6241 tttatatctg tctacctttt caaaacttac ttgaaaaagt cggttttcca agatgggcta
     6301 gtataacaac aatcatgtta gctttgtttg ctattatcgg cttaattgtt gcgtttgttg
     6361 caccaatcat catttcaaat atcaacaatt taattagtca gacacctgcc ctacaaaaag
     6421 aagcagagca aattattaaa ttcgcactag ctcaaatgga taaattacct gaagatgtaa
     6481 caagtagaat tacaaatatg gttaaatcaa tgggtgatgg cgttactaat attttatcta
     6541 attcattaca gtacattaca tcattaattt caaccatctt cttattgatt atggttccat
     6601 tcttcttaat ttatatgtta aaagaccatg aaaaatttat cccagctgtt gctaaatttt
     6661 tcaaaggtga acgtaaagta tttttcgtag atttattaac tgatttaaac tttacattaa
     6721 aatcttacat tcaaggtcaa gtaactgtca gtgttatttt aggtatattc ttatatatcg
     6781 gttattcaat tattgactta ccatatattc ctttattagt tctatttgct ggtgtcgcaa
     6841 acttaattcc tttcttaggt tcatggttat catttgcacc tgcagcaata ctcggtatta
     6901 tagatagtcc tactacattt atatgggttt gtatcattac attaattgca caccaacttg
     6961 aaggtaatat cattacgcca aatgtaatgg gtaaatcttt aagtatccat cctttaacaa
     7021 ttatcgttgt tattttagca gcaggagatt taggtggctt tacattagtt ctgattgcag
     7081 tgccattata tgctgtactt aaaacggttg ttagtaatat tttcaaatac cgccaacgca
     7141 ttattgataa agcaaacagt aatgttaagg actaattctg tggatgtctt ttaagaatat
     7201 aagatactat ctcctcaaaa gttgaaacta cagcttttga ggagattttt ttgtgcataa
     7261 aaaaaatcag tcagatgaaa tatcaaataa ttttccatca gtccgattat tataaaagca
     7321 aaaaagcttt gctcacatat atgataacgt gaacaaagct gttgaatgat attatttaat
     7381 tgcgtggaat ccgctatcta catgaatatt ttcacctgta acgccacttg ataagtcact
     7441 taataagtaa gccgctgttt tacctacttc tacttgatca acgttacgtt ttaaaggtgc
     7501 acgctcttcg atttctttaa gaattgtatt gaaaccaccc acaccttttg cacttaatgt
     7561 acggattgga ccagctgaaa ttgcattaac gcgaatatta tcaggaccta agtctaatgc
     7621 taaatattta acatttgctt ctaagctcgc tttagcaaca cccatcacat tataattttg
     7681 aactgcgaat tcgccaccta aatatgttgt tgcaacaatg ctaccacctt ctggcattaa
     7741 ttttttagct tcatgagcca caattgttaa tgagtaagaa ctaatgtctt gagctaacaa
     7801 gaagccttca cgtgaagttt cagaaaagcg tccgcgtaag tcttccatat tagcaaatgc
     7861 gattgaatga tatacaccat caatattgcc aacatcttta ccaatttgct caaaaccatt
     7921 aataacctct tcatcgcttt gaacatcaat ttgatataag tgcgcttctg gttgatttaa
     7981 ttgttctaat aatttttcaa gctctttacg gctacgttct ttacggtaag taaatactaa
     8041 tttagcacct aattgatcta aaactttagc gacaccaaaa gcaatactac gcttattagc
     8101 gattcccatg atgacatatg ttttgttttc aagatttaac atgtaagata actccttata
     8161 ataattaatt taacggatag aatatctaat cccagtttta actaactttt tattcgtcaa
     8221 tacattttaa cactattatg actttttaat aaagttattt aaacgtatta caacgataaa
     8281 tgtttgattt agtcctttct gtatcaaact tgatttacgt aaaaagcatt tatttatcaa
     8341 aatcatatac atactagcat tttaaaatca ttaattttac gtcgtactaa aatacgtctg
     8401 cattttaata tcattattgt taaaaataaa attctaactc ttgcttcaat tcatcaacgt
     8461 attctttagc cccggtaaca attaagcgat ctccatatcg caattgtgta tctccatgcg
     8521 gaacaatcga ctcattatta cggataatac gcacgaagat gatgtctcct ccgaatggga
     8581 aattacgtaa ttgaatattt tcatatttat aatttaacat ttgaatttca tatagtgatg
     8641 tttcaacatt acttaataaa ttcaacatgt taggtgtttc aattaaacct tttaataaga
     8701 ttttattact taagtagcta ctgaaaattt caatacctga atcaactaac tctgtatcgt
     8761 ccgttgtgct ttcaagtctg caaatgacac gctcaacttg atgtgctttg gctaatttag
     8821 caacttttcg gttaatatca tcgtcattcg tggcacaaac aactatgtct cggtcaaaca
     8881 gacctagtcg ttctaaaaca tcttgttcat aatcagcaat ttctatcatc gtgatatcat
     8941 ccgacaattg acgacgatca ctcaaatctt tgcgataata taatgtcacg tcatataact
     9001 gagatgttaa attttgcgct ataggaatcg ttaattgatt tttaccaatt aaactaacat
     9061 caattttacg gttaaactca tctggaactg gaaacagttt tttgaaaata atcggaacga
     9121 atacacatgt aatgactgcg cttaaaatta atatacctga cgtttcagct gaaatagcat
     9181 ttaatctttc tgaaattttg gctgcagcta tcacgagcga taatgttgat gttaataaaa
     9241 atgctgatgc aatcgttgtt ttcatatcaa accaacgtcg aataaacatg actggaatta
     9301 attttgaaat gataaatgca acgattaaaa tcggtatgat aattagtaat ttcggttctt
     9361 taattaatga aggtatgttt aaatctacac caaccattat aaagaaaata ggaataaaga
     9421 acccataacc aaatgagtct aacttttcaa ccatttcttc atctggattt aataatgaaa
     9481 caacgacacc tgctaagaat gcacctaata tattttctgc gccaactccc tctgctaggg
     9541 ctactaataa tattattaat gcaaacaccg cacgaatacc gatttgcgtc gtaccatcca
     9601 tcaatttttg taaaaatgac attcttttaa attgaacacc taaaatatat gaaattgctg
     9661 tgaaaacaac taatatacct attaaccata ttgtactgcc gccttgacca ttgattgcac
     9721 catagaccgt taataaaatc atagttacta agtccgcaag tactgctact aataggatga
     9781 attgacctat agttgttctc ataatattca tttcttttaa agttggaaca actacgccta
     9841 aggaaatagt tgaaatgata atgaccatta ataacacatc atccactaat ccaagccatt
     9901 taaatacata cgctaacaga atcgaaataa tcataataaa tgcaaataca gttaacgcta
     9961 gattaagatg ccctggaatt gaggattcat catcattttg tccttgacgt gcgcgtttat
    10021 cttttttaaa agctttaaaa tcaatttcta aaccacttaa aaacattaaa aagataaagc
    10081 ctaacgttga taaaatattt agaattgaat ccctttctac tatatttaga aatgaatttc
    10141 caatcacaat ccccatcaaa atttctgcaa caacaactgg caagaaatta atatttaatc
    10201 gattgacaat tattggagtt aaaaacgctg ctaaaacaac aataactaaa gataaaaact
    10261 ccataactcc tccttaaatt aagtaagcca taaatgatgt agctaaacca aaataaatca
    10321 acatactaat aatatcatta attgttgtaa taaatggtcc actagccact gctggatcga
    10381 tatttaattt attcatcaat aatggaatca tcgaacctac aaacgtcccc accgtcatcg
    10441 cacaagttaa acttcctgca acgattaatg ctaaaagtgg ctgatgatat attgcaacaa
    10501 taattgtaaa taatattgtt gaacatacaa cacccgataa tacaccactt cccgcttctc
    10561 ttaatgcaat tctaaattta ctttgctcat taatttcccc tgtcgtaatg ttacgaactg
    10621 aaacggctaa agattgtgta cctgaatttc ctgacatacc actaataata ggaataaacg
    10681 ctgcgagtag cgctacattt tctaatgttt tttcgaatct ccctaaaatt gtcgcagtaa
    10741 tcattcctaa aaatgttaaa ataatcaacc atggtaaacg ttttaatgct gttttaatga
    10801 ttgaatcatt agtcgaatcg atatctgaaa ccccggctaa acgagagtag tcttcactag
    10861 cctcttcatc cataacgtct aaaatatcat caatcgtgat gataccaagc aaatgttctt
    10921 ggtaatctat aacaggtaca gccatgaaat catagtctct cataacttga gcaacatctt
    10981 cttggtcgtc tgctacattc acactaatga cacgttcatt cataatatct tcaatataag
    11041 catcattttc agctacaatt aaatctctta gtgataaaac acctactaat ttaccatcat
    11101 catcaacgac aaatataaca tatattgttt ctgcgtctgg cgcttgcgct ttgaccaata
    11161 ataacgcttc tttaacaggc gtatgcgctt taagtgataa atactccgtc gtcataatac
    11221 cgccggccgt atcctcatca tagtgaagta atgctttgat ttcattcgcg tcatctttat
    11281 tcatcaatgt taaaagacta gcaacttttg gtttagtcaa ctcatttaaa atatctactg
    11341 cattgtcgta tgacatttct tctaatatgt gacttgcgta tgtcgcattc attttatcaa
    11401 atagcaactc atattcatcg tcatcaatat ctaattgatc aaagaaattt gcaacttctt
    11461 caggtgataa atattgaaaa atcttttgtc tattttcatc ggtagtatct tcaaaatact
    11521 cactttgttc atatgtgtgt aatgctagaa attcatctct aaattgatca atatcatcat
    11581 tttctaagta ttgatctaat aaagtttggt cgtataattc ctcttgaaca cgctcttttt
    11641 catctgtgtt cattgacata cttacacccc ctgtgtgaat tagagttgat tgaataattt
    11701 aagtaattgc ttataatcaa ttgtaatata aatattgttc ttattgattg gatgaacaaa
    11761 atatatttgc gtacattgca gtacttgacc atgaattttg tcatgaaaac catcatacaa
    11821 agaatctccc acaattggat gcccaatatg ttgaaaatgt acacgaattt gatgtgtacg
    11881 tcccgtatgc aaatgaactt tgcataaact gtatttatca ttctgattta ttacttcata
    11941 agatgtttta gcgtatttac catccgaggc aacttctcta gttataatac tatcctttga
    12001 ccgtctaata ttagcttcaa taataccaga tgtatgggtt ttaccatata caaggcaagt
    12061 atatattttt ttcaagttta ctttagaaaa taaatgatgg atatgtccat atttagcgaa
    12121 tatcacaata ccagtagtat tacgatctag acgcgtaaca atatgtgggt taatattttc
    12181 accatgttcc tgacaatgat atagtacttg ttcgattaaa ctttcatgag gatgttctct
    12241 cgaaggcgta caattttgat tgtttggttt agtaactatg atgataaaag catcttcata
    12301 caatacttct agcttacgag cataaggtat taaattaaca ctcggtattt ctcgtggtaa
    12361 atgaatttct aatatatcat ttggcattaa ttgcttacgc actgtgactg gttcatcatt
    12421 aacaattaaa gcgccattat ttttaatggc gctcactgtc ttcttagaaa aatcatgtcg
    12481 tgctaaaaaa gttttaacag tttcttgttg tgatatatga tacttaaatt tcatcgttct
    12541 tcatcacttg atatgaaaga atcgtgtaca cgtttccaga atgggaatgg tctaaaacgt
    12601 gcaaacctca ctttttcatt tgctacacgg tattgtattg aattaacatt tttatgtttg
    12661 atactaacat gatctatcgt cattctaatg gtatcatgat taactggtga tattaaacat
    12721 gtatgatgct ttggtaatac aagtggtgat cctaccgttc taaacacacg attatttatt
    12781 gaggcaattt ctgtaatttg cattgcttca agtgaaggat gtatcagtgc gccacctagc
    12841 gctttgttat aagccgttga acccgaaggt gttgatacac ataatccatc gcctctaaat
    12901 cgctcaaagt gtttccctct taagttaaca tccacaacaa gtgttgagcc attttcagtt
    12961 ttcatcgttg cttcatttaa tgctaaatac cttgtttcat atccgttgtc gttgtatctc
    13021 ataataattt caagcaatgg atattcaatg acctgaaact ctgaattatt aatttcgatg
    13081 attaattttt caacttcatg aggtaaccaa tccgcataaa atcctaaatg acctgtatga
    13141 accccaacaa atgccacttt tgataacatg tggctatact gatggaatgc ttgtagtaat
    13201 gtaccatcac caccaactga aataacaatt tcaggatttt cactatcctc aatcatgcga
    13261 aaatctttca tatagttcat cattttatgc tttaaggcat tagacttgga gtcaccttta
    13321 gttaaaattg tataacgcat gatttataac acctcgttaa tcattttcat gttttttaga
    13381 acgtttttgc gtgtaatatt tttgagcttc ctgaatttca tctttaattt cagacatctc
    13441 ttcatcaagt aaatacgctg cttctgccgc tctttccaaa cgatgttgaa tttcatccgg
    13501 ataagcacca tcatatttat atcgtaaagt atgttcaatc gttgcccaga aattcattgc
    13561 taatgtacga atctgaatct cagccaatat aaatttttgg ccttgtaatg tttcaattgg
    13621 atattcaata atgacatgat acgagcggta accactttct ttagtgttac gaatataatc
    13681 tcgttcttca attaccttaa aatcttttct ttgtcttaaa atattgacga caacatcaat
    13741 atcttctaca aattggcaca tcattcttaa accagcgata tcgtacattt cttctcttaa
    13801 cctatcaaat ggtatttgtc gtttgtttgc cttatctata atactagcga ttggtttaac
    13861 acgaccagta acaaattcta ttggcgaggc ttgttcacca acttcatatt gtttgcgcat
    13921 gcctttaagt ttcactttta actcatcaac cgcttgctta taaggtgtta agaactgatc
    13981 ccattgattc atagtgcttc accccgcttt attcaatgtc gaatgtttct tcaacggttg
    14041 caacaaattc cttaccataa ttattatttc cttttatgtt gtctaaaata taagtaagtt
    14101 cttggtggaa ttcagtcaat tctagttcat cattgataat aattttttta gtcatgtttt
    14161 catgcaacat cgtccatgtt tcttgtacga aaatgagata agcatacgct ttaccatcat
    14221 ctaatgtata cgcaaaggca taattatcac tatcaacgag catttgtcct acttcagata
    14281 atcctttaat agaatcttct gtataacaat aaagtatgtc atctttaatt ttaatttcat
    14341 taatatataa acgcatgctt aatcctcctc ttattccata acattttaac acaattcaat
    14401 aatacaaaac acttacgaac actattttta atggtcaaat taacattgat aatagataaa
    14461 ggaaattact tttaaaattc aactttgtca ttcataatat agttaagata aattgaattt
    14521 gatacgaggt gtatacatat catggcaaca aatcatgaaa tagaatttaa acaaatgata
    14581 actgcatcaa tctataataa attgcaagag aaatatttta aagacagtgt gctgtttaag
    14641 caagtcaatt actatattga tacacccgat ttcaaattaa aggaacatcg ctctgcacta
    14701 cgcataagag ttaaagacaa tcaatatgaa atgactttaa agacaccagc aaaggttggt
    14761 ctattagaat acaactatat cgtcgacatt aaaccagaga tgaacttgat tatttcaaac
    14821 gacaatcttc cagatgacat tcgtcaaatt atagttgaac agtttggtgt aaaggataca
    14881 actttatcaa tacttggtgc attaacgaca tatcgccaag aaactaaata taaaggtgat
    14941 ttactcgttt tagataaaag tgagtatttc gatactacgg attatgagtt agagttcgaa
    15001 gttaaagact ataatcaagg tttacaaaag ttccaatctt tattaaacga actaaacctc
    15061 gaacatcatc aacctttaaa taaagttcaa cgttttttca agaaaaaaga aacactttca
    15121 aacaatataa attaaattgg caaatatgca tatttctttc aaatgtttaa aatcatgtta
    15181 tattagttat atattaactt aagttcgtaa cagtaaattt ttgaaaatgg gtgattaaat
    15241 gacaacaaca ccatatgaca tcattggtaa agaagcgtta tacgatatga ttgattattt
    15301 ttacaccctt gtagaaaaag atgaacgact taatcacctg tttccaggag attttgcaga
    15361 aacaagtcgt aaacaaaaac aatttttaac acagtttttg ggcggtccaa acatttatac
    15421 cgaagaacac ggacatccta tgctaagaaa aagacatatg gattttacaa tcactgaatt
    15481 tgaaagagat gcatggttag aaaatatgca gacagcaatt aatcgcgctg cgtttccaca
    15541 aggtgttgga gattatttat ttgagcgctt aagattaact gctaatcata tggtgaattc
    15601 ctaaaattaa ttgtaggtga ataaacatgg ctggagaatt acgaataatg gaaaataaga
    15661 gtcgtgaaga tattaatcta tcacctgtaa gtaaaatcga aatttattca tttttcgatc
    15721 catttagctc cgattgcttc aaattatcag caatcttatc caaattaaga attgaatata
    15781 atcaatatat acgtatcaga catatattaa atccttcgtt aaaagtatta acgaaatgcc
    15841 aagctcaaag tacatccaac tttgataaca tcgccctagc ttataaagca gctgagttac
    15901 aaggtcgtgt acgtgccgaa cgatttatac atttaatgca aaatgaaatc atacctaaaa
    15961 gagatattat tacagaatca atgatttgtg actgtattca aaatgcaggt attgatttag
    16021 aagtatttaa agacgactta caaaaaagta aactaaccga aagcttgaaa attgatttgc
    16081 atattgcaag agaaatggaa atcgaacaag ccccttctct cgttttcttt agtgaagatg
    16141 ttcatgaaga aggtttaaaa gtcgaaggat tatacccata tcacatctat acttatataa
    16201 ttaatgaatt gatgggtaaa cctatcgaaa agaatcttcc tcctaaatta gaaacttata
    16261 tacagcaaca acaacttgta acgatggaag aattacttac tatttatgaa tggccagaaa
    16321 aacttttaaa caaagagtta aagaagttag ccattcaaca aaaaattgaa aaacttaaat
    16381 atccagatgg cgatttctgg aaatctaaaa tgcctaaaat caaatcaaaa taaataaatt
    16441 aaagacctcg tacaccataa atgtaacgag gtctttttac tgactcttaa ttttgcaaca
    16501 ttaaattatt agaacgtaat gttacacatc gatctaaata tattagtgat atttttcgaa
    16561 tttaaccagt tcgaaaatta tacaaattat aaatttggta cataatagac ttatattaat
    16621 cgttaatgta taaaaagtgc atatttaata catttttata caacttcact tccctcttat
    16681 taaaaaagaa cataaaaaaa cgtcgtgtct gaatacacga cgctaaacaa aggggatggg
    16741 agaaattttt cacttcaaac aaaggggtat gtttgttatg tgattaattt catgttcata
    16801 atataacatg ctatctctac catttcaacc ttttaatagt acttaattta aattgtcaca
    16861 atctgttcat aatgtaagcg aattcaatag tactaagctt tcattaattt ttcaaaagcg
    16921 ttcaattttt gttcaaaaac ttcacaagct tgttcaattg gttcaggtgt tgtcatatct
    16981 acaccagcat tttttaatat ctcaattgga taatttgagc tacctttttt caagaattca
    17041 ttaatatatc tatctactgc tggcttacct tctgttaaaa tttgatgact taagctttga
    17101 gctgcactgt aaccagttgc gtattgatat acataataat tcatatagaa gtgtggaata
    17161 cgtgaccatt ccttactaat atcttcatca gtttctacag aatcaccgaa gtataattta
    17221 tttaatttgg catattcttc attcattcta gttggcgtta atggttcacc tgcttcttca
    17281 attgcatgaa ttttatgctc aaattctgcg aacattgttt gtcggaataa tgtagctctg
    17341 aaacgttcta attcttggtt taataataat aagcgttttt catcatcaag atgtttatcc
    17401 atataatcac ttaaaagtgc ttcgttacaa gttgatgcaa cttcagcgac aaaaatagtg
    17461 tagtcactag aatttgacgg ttggaatttt ctactgaagt aactatgtgc tgaatgccca
    17521 aattcatgaa ctaatgtgta taagtctgaa atagtattag accagttaag tagaataaat
    17581 ggattagtta aatgtgcacc tgatgaatag ccacctgaac gtttaccttt attctcatag
    17641 acatcgaccc aacgattgtt taagccttct ttaactacat ttaaatattc ttcacccatt
    17701 ggttctaatg cttttaacat ccactcttta gcttcttcat aaggcatttc aaacttaata
    17761 tctttaatta atggtgtata taaatcatac attttcaagt catctaaacc tagcaattct
    17821 ttgcgcaatt cagtatatct atgtagcaat ggtaaatatt tatgtacagt ttttactaga
    17881 ttgtcatata cattttctgg aatatgatta ttactcaatg ctttttctct tgcagttttg
    17941 taattgtgtg tacgagcatt aaatacattt ttcttcactt cacctgctag tgtagcgcca
    18001 agcgtattat tatgagcacc atatgcttta tatacatttc taaaagcact ttctcttagt
    18061 ttgcgatcat ctgattctaa atacttaata aatgtacctt gtgttaacgg gtgtgcattt
    18121 ccatctttat caatcgcatc ttcaaatact aaatcagcgt tgctaaacat accgtataca
    18181 tttgatggcg ttgataacgc gtcctgcgct tctgttaata acttttcagt ttcagcatct
    18241 aaaatatgag gacgtttttc attaatcaac ttcaaatcaa atgcgaattt ttgtaattta
    18301 tcatatgaat ttacaaatga ttgaatttta tcttcatcaa tttgtaaaat ctctggcact
    18361 aagaaactcc atgccgagct aaatttaata attaattgat gtgctcttga ctccatacca
    18421 gtatacttgt cgttcgttgt atcttggtct tgttttaggt gcgcgtatac atatactttt
    18481 tctaatttag tacctaatgt atcttctaat tctaacgcat tgtataatgt ctcagcacta
    18541 tcaccaatgt gtcctttaaa ttgttcttct ttgcctaact cattttcaac ttctttaaat
    18601 gcagcctcaa aagcttcatc atctttgaaa attgttgtta agtcccatgt atattcagga
    18661 tatttacgtt cctgttcttc tctcgataat tgttgactca tatgtagtaa acctcctaat
    18721 aaaatataat tgatataatt ttctcatttt agaacaaaat ttgcacgtca ttacctctat
    18781 ctgaacaaat atttaaataa ttgttaataa gtttttctat aattgctgtt ttactttcta
    18841 gagcaacaat aaattttttc agtttaaaat aattaaggtt gtcatttact aatttgcttt
    18901 ttccattctt taacaataaa tcaacttgta attgccactc aataggatga ttttcaatat
    18961 aaatttgctc tggaaaaata taaccataat tgtgcactac ttcttgatca gttaactgta
    19021 attgatacat tgcacttaaa gtgggttcta aaacggaatt ttgccagcga caatatttga
    19081 tatattgatt aattgcgaac tttgataatt tataaacagc atgataatca caaggcgcct
    19141 cattaaacaa ctcaataatt ttggcattcc ttttttcagc aacatatttg tgcccgccta
    19201 aatattgtat ttgttgaaac atcattattt gttttttctc taaattgaac gtatgaagtt
    19261 ttcgagtgat tggattaata aacaaacttt gaaaatgatt gaacttcact ttattatgac
    19321 aataatcaac atcatttaat aaccaactta ctttatatcc cattttcttt aaaccttccg
    19381 ttcgttgaag aatctgttta taaggaattg gcgaatactg tagctcaata acatatttat
    19441 tattaatcaa aatatccgga atttgtttta tttcttttaa aaatggctct atctctactt
    19501 tacatccttg ttgctgtatc atctgtgcta aaatcaattt acttttataa tgtttaatcg
    19561 tttcattatt aaaacatttt tgttccgcta aatgtttatg tgcaaaatga ctaattactt
    19621 tgagcccacg ctttaaaata acttgcttgc cacacaccgg acaaaaatat tgtgtctttc
    19681 tcaatacagt agttgctaac acacgttcct tttcttcatt taaagctact aacatatctt
    19741 cacctcaaaa tattacacgt aagtttaact actattactt tttcagcttt tgaaatcaat
    19801 aaaaaaagag actccaaaga gtcccctttc atagtgcgtt gcttaattaa tatcgttatt
    19861 cagttgtctc tggaaaataa cgtcgaactt gagctgttac gttatgactc ataattattt
    19921 tagcatagtc atttaaataa acttctgttc tgtctgttgg ataagcaaat tcaagcaatt
    19981 gactgtaact atcattaatg acttcttgat caacatgact atcaaaatgt acagcataat
    20041 aataagtacc atcaaccata tataacaaat cttcaaactc tgtagttatt ggattgctat
    20101 gatatgcata attaataaca tcttctaaat cgttaaattt cacaataatt gttcttgtat
    20161 ttttacgtgc tgaagacttt tgacgtttag aaccttgagc gtctttttct tttgttcgtt
    20221 gctcgaataa ttcttctaat tgatcttcac cttctaatgt ttgagctaac aattcttgaa
    20281 cttgttcatc aaattgatca gttgcatcat catcagacat attcatcata tcttcatttt
    20341 tagatttaga aattgtgact tcgacacctt tttcaaaggc atgtacttga atccataatg
    20401 gaccttctac aacaaaatct tcttcttcgt taatttcatc catcattgac caaaagaatt
    20461 cttcgccacg tttgcgattt gtccataaat cttcacgact aaatccacgg gcctcgatat
    20521 cgctatatgt tataaacaat tttacagttg tatcatctac tcgttctatt ctcatatcat
    20581 ctcactcctt acagtcgatg aatagtatcc acattgtatt aaagcatcaa acaaaataca
    20641 atttatttgt ttgatttctt tctctaaaat attttggtaa cttataataa catattcgtt
    20701 gtagcaaaac tatttaaatg atttatacag ttaaagcatt aaagcacttt cttaatttaa
    20761 ttttacctta tcatagcaaa tgtttcatcc aaaacactct aatatagagc tatattaaca
    20821 attgcacatt tgatttaaaa gatactaagc aattattgta aaat
//
LOCUS       DAPSKH010000052        20045 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPSKH010000052 DAPSKH010000000
VERSION     DAPSKH010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 20045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20045
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.052"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            135..506
                     /locus_tag="RPH49_002008"
     CDS             135..506
                     /locus_tag="RPH49_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5125137.1"
                     /translation="MEKLNQVMLYVDDVDKAKAFWTETLEFVVVSETPLAEDYVAVEV
                     SPTKDAETSLTIMAKEFIEKYSPEVNLGTPSLMFKEKNFDALYSKLNDLGLTGHDIVE
                     MNGQRAFNFQDGQGNYFAVSD"
     gene            445..681
                     /locus_tag="RPH49_002009"
     CDS             445..681
                     /locus_tag="RPH49_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125138.1"
                     /translation="MVNVHLISKMAKVTILQLVTKQSILIFIQTFILIFGLNFSMKVL
                     FLSFYAIVCTNLLTFLESVTKLVLYNGWKRFPAQ"
     gene            700..1719
                     /locus_tag="RPH49_002010"
     CDS             700..1719
                     /locus_tag="RPH49_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDY5125139.1"
                     /translation="MVTIKDVALKAGVSPSTVSRVIKGNQRISEATISKVKKVMEELN
                     YFPNTAARTLITNQTYKIGLVLKGSEEPIRLNPFYINVLLGISETCNQHGYGTQTTVS
                     NNLNDLMDEVYKMIKQRMVDAFILLYSKENDPIKQMLIDESMPFIVIGKPTSDIDHQF
                     THIDNDNILASENLTRHVIEQGVDELIFITEKGNFEVSKDRIKGFETIASQNKINYQI
                     IETSNEREVIFNYMQNLHTRLKDPNIKQAIISLDAVLHLAILSVLYELNIEIPKDVMT
                     ATFNDSYLTEIASPPQTSIDIEPRMLGQQAGAAILNILKNKAQDVIELVIIDTELKIR
                     KSTQR"
     gene            1735..3384
                     /locus_tag="RPH49_002011"
     CDS             1735..3384
                     /locus_tag="RPH49_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDY5125140.1"
                     /translation="MNKQWWKEAVAYQVYPRSFNDSNHDGIGDLPGMIDKLDYLKDLG
                     IDVIWLSPMFKSPNDDNGYDISDYQEIMDEFGTMEDFDRLLKGVHDRGMKLILDLVVN
                     HTSDEHPWFIESKSSKDNPKRDWYIWQDPKPDGSEPNNWESIFNGSTWEYDANTEQYY
                     FHLFSKKQPDLNWANPEVRDAVFEMMNWWFDKGIDGFRVDAITHIKKTFEAGDLPVPE
                     DKTYAPAFDVDMNQPGIQTWLQEMKDRSLSKYDIMTVGEANGVSPDDADDWVGEENGK
                     FNMIFQFEHLGLWNSGDSHFDVNSYKSVLNRWQKQLENKGWNALFIENHDQPRRVSTW
                     GDDDKYWYESATSHAAVYFLQQGTPFIYQGQEIGMTNYPFESIETFNDVAVKNDYQIV
                     KAQGGDVDALLAKYKDENRDNSRTPMQWDDTLNGGFTNGEPWFPVNPNYKTINVAQQL
                     EDEHSVLQFYKDLIQLRKSNDVYVYGQFDLVDAENSQVFAYTRTLNEKQVLIVGNLTN
                     HEAELTVPFDLSHGEVELFNYDAKVNLKQLRPYEACVIELN"
     gene            complement(3466..4332)
                     /locus_tag="RPH49_002012"
     CDS             complement(3466..4332)
                     /locus_tag="RPH49_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDY5125141.1"
                     /translation="MDVIKQIQQAIVYIEDRLLEPFNLQELSDYVGLSPYHLDQSFKM
                     IVGLSPEAYARARKMTLAANDVINGATRLVDIAKKYHYANSNDFANDFSDFHGVSPIQ
                     ASTKKDELQIQERLYIKLSTTERAPYPYRLEETDDISLVGYARFIDTKYLSHPFNVPD
                     FLEDLLIDGKIKELRRYNDVSPFELFVISCPLENGLEIFVGVPSERYPAHLESRFLPG
                     KHCAKFNLQGEIDYATNEAWYYIESSLQLTLPYERNDLYVEVYPLDISFNDPFTKIQL
                     WIPVKQSPYDED"
     gene            complement(4562..6046)
                     /locus_tag="RPH49_002013"
     CDS             complement(4562..6046)
                     /locus_tag="RPH49_002013"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDY5125142.1"
                     /translation="MSTKNKHIPCLITIFGATGDLSHRKLFPSIFHLYQQDNLDEHIA
                     IIGIGRRDITNDDFRNQVKSSIQKHVKDTNKIDAFMEHVFYHRHDVSNEESYQELLDF
                     SNELDSQFELKGNRLFYLAMAPQFFGVISDYLKSSGLTDTKGFKRLVIEKPFGSDLKS
                     AEALNNQIRKSFKEEEIYRIDHYLGKDMVQNIEVLRFANAMFEPLWNNKYISNIQVTS
                     SEILGVEDRGGYYESSGALKDMVQNHMLQMVALLAMEAPISLNSEDIRAEKVKVLKSL
                     RHFQSEDVKKNFVRGQYGEGYIDGKQVKAYRDEDRVADDSNTPTFVSGKLTIDNFRWA
                     GVPFYIRTGKRMKSKTIQVVVEFKEVPMNLYYETDKLLDSNLLVINIQPNEGVSLHLN
                     AKKNTQGIETEPVQLSYSMSAQDKMNTVDAYENLLFDCLKGDATNFTHWEELKSTWKF
                     VDAIQDEWNMVDPEFPNYESGTNGPLESDLLLARDGNHWWDDIQ"
     gene            6359..7279
                     /gene="rnz"
                     /locus_tag="RPH49_002014"
     CDS             6359..7279
                     /gene="rnz"
                     /locus_tag="RPH49_002014"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDY5125143.1"
                     /translation="MEVTFFGTSAGLPTKERNTQAIALNLEPYSNSIWLFDVGEGTQH
                     QILHHAIKLGKVTHIFITHMHGDHIFGLPGLLSSRSFQGGEQKPLTLVGPKGIKAYVE
                     MSMNLSESHLNYPITYIEIDDHLTYHHDGFTVEAHLLNHGIPSYGYRVMAPETTGTIN
                     VEALKNIGLEPGPKYQEVKSHDTFEHNGQVYQSKDFRGESKQGPVVAIFGDTKPCSNE
                     RVISRDADVMVHEATYIDGEKHLANNYHHSHIEDVFALIKEANVKRTLITHLSNRYNT
                     EDINEIYQTLIQNEDTPNFNFVKDFDSFKV"
     gene            complement(7382..8197)
                     /gene="proC"
                     /locus_tag="RPH49_002015"
     CDS             complement(7382..8197)
                     /gene="proC"
                     /locus_tag="RPH49_002015"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDY5125144.1"
                     /translation="MKLVFYGAGNMAQAIFTGIINSSNLDANDIYLTNKSNEQALKAF
                     AEKLGVNYSYDDATLLKDADYVFLGTKPHDFDALATRIKPHITKDNCFISIMAGIPID
                     YIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEINDLVKAFGSVIEVS
                     EDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLIIGTSKMIERSD
                     LSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDRSIELSNIEDQ"
     gene            8339..9094
                     /locus_tag="RPH49_002016"
     CDS             8339..9094
                     /locus_tag="RPH49_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5125145.1"
                     /translation="MKGQHFIVTGGTSGLGLSIVRKLLENKVHVTLLVRDVDKATRIF
                     EQELGKTINVIPCDLNDLKSIQALQFEDNTSFDGFIYSAGLGYFKSISDHSFSEMIET
                     YQLNLISFNVLYTVLRPYLTSNAHIVGISSQAAFSTQANAAHYGASKAGFYALMNALR
                     LESPNIHIMTVNVGPIDTPFHQKADPSMKYAKKMGKIMLDANQLAEDIIYGIKTKQLE
                     INRPKWMHHALKMYQIAPRFFERCFPKLFKNKA"
     gene            9110..9358
                     /locus_tag="RPH49_002017"
     CDS             9110..9358
                     /locus_tag="RPH49_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125146.1"
                     /translation="MNCQSESVVRLCVRYAEQLSVFEEFTVLDILGDISVDQISDSTL
                     YYTCEKFKLLVLQGNVLGVQIITNNDESTCEVKYRKMF"
     gene            complement(9574..10482)
                     /locus_tag="RPH49_002018"
     CDS             complement(9574..10482)
                     /locus_tag="RPH49_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDY5125147.1"
                     /translation="MQKNILKSGISLSELGLGCMSLGTDLKKAEQIIDCAVENGITYF
                     DTADMYDKGINESVVGKALLKYQQRDDIVIGTKVGNRLTKDGSTTWDPSKSYIKEAVK
                     GSLKRLGIDHIDLYQLHGGTIDDPLDETISAFDELKQEGIIRAYGISSIRPNVIDYYL
                     KHSQIETIMSQFNLIDNRPESLLDAIHNNDVKVLARGPVSKGLLTSNSVNVLDNKFKD
                     GIFDYSHDELGETIASIKEIESNLSALTFSYLTSHDVLGSIIVGASSVDQLKENIENY
                     HTKVSLDQIKTARARVKDLEYTNHLV"
     gene            10564..11106
                     /locus_tag="RPH49_002019"
     CDS             10564..11106
                     /locus_tag="RPH49_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDY5125148.1"
                     /translation="MDLNEKTIDRTVIYNGKIVDVEIHTVTLPNGETSTRELVYHNGA
                     VAVCAVTPKKEVVLVKQYRKPVEKPLLEIPAGKLEDDEDRVEAAKRELEEETGYIAKE
                     LTHVVDMYGSPGFCDEQLSIYFTDNLEEGTVHLDEDEFVEVIKVPIENVKSMLMNKEI
                     EDAKTIIALQHLLLNYNHSK"
     gene            11211..11660
                     /locus_tag="RPH49_002020"
     CDS             11211..11660
                     /locus_tag="RPH49_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDY5125149.1"
                     /translation="MEERLNRVKQQLQQSSYKLTPQREATVRVLIENEKDHLSAEDVY
                     LKVKDKAPEIGLATVYRTLELLAELKVVDKINFGDGVARFDLRKEGAKHFHHHLVCME
                     CGRVDEIDEDLLPEVENRVENEFNFKILDHRLTFHGVCETCQAKGKG"
     gene            11709..12596
                     /gene="xerD"
                     /locus_tag="RPH49_002021"
     CDS             11709..12596
                     /gene="xerD"
                     /locus_tag="RPH49_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDY5125150.1"
                     /translation="METIIEEYLRFIQIEKGLSSNTIGAYRRDLKKYQDYMTEHHISH
                     IDFIDRQLIQECLGHLIDQGQSAKSIARFISTIRSFHQFAIREKYAAKDPTVLLDSPK
                     YDKKLPDVLNVDEVLALLETPDLNKINGYRDRTMLELLYATGMRVSELIHLELENVNL
                     IMGFVRVFGKGDKERIVPLGDAVIEYLTTYIETIRPQLLKKTITEVLFLNMHGKPLSR
                     QAIWKMIKQNGVKANIKKTLTPHTLRHSFATHLLENGADLRAVQEMLGHSDISTTQLY
                     THVSKSQIRKMYNQFHPRA"
     gene            complement(12674..13180)
                     /locus_tag="RPH49_002022"
     CDS             complement(12674..13180)
                     /locus_tag="RPH49_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF309 domain-containing protein"
                     /protein_id="HDY5125151.1"
                     /translation="MQQALINFYYQFHTKQHYFLCHDILEDAWKAENNYSKQDAVVSL
                     ILFATACYHYRRNNLKGAYKSFNKSKEIIQNAKDRDALYLNLNDYQLLIEQQIAKLNA
                     AKPFSSVILPITPVFERIIKANYPDYDYNQETATDPFIVDHHMRRDRSEVIAAKEEAI
                     QLRKHRRN"
     gene            13272..14003
                     /locus_tag="RPH49_002023"
     CDS             13272..14003
                     /locus_tag="RPH49_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDY5125152.1"
                     /translation="MYEVKLDAFNGPLDLLLHLIQKFEIDIYDIPMQALTEQYMQYVH
                     AMKQLEINIASEYLVLASELLMIKSKMLLPQSTSDMDVDDDPREDLVGRLIEYQNYKE
                     YTAILNDMKEERDFYFTKRPTDLSHLETDESWDPNHTIDLTELIVAYQRVKNRVELNT
                     PKSVEIRKETFTIQQATEQVTSRLKDKDHFNFFSLFTFSEPIEQVVTHFLAILEMSKA
                     GIINIEQQRNFEDINIIRGVNYHFG"
     gene            13996..14538
                     /gene="scpB"
                     /locus_tag="RPH49_002024"
     CDS             13996..14538
                     /gene="scpB"
                     /locus_tag="RPH49_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDY5125153.1"
                     /translation="MDNHGILESLLFTAGDEGLDEKQLLEILDMSKDQLVELIENYSS
                     HGLMIQRFGTTYVLTTKKEAATYIEQLIEQKSQMKLSQAAMEVLSIIAYNQPLSRSDI
                     ELIRSINSDGAVKTLIAKGLVEAKVVNEQRSQQLITTDLFLNVFGISNIEDLPTTEED
                     DEEMDAFFSNLVNQKGENND"
     gene            14531..15268
                     /locus_tag="RPH49_002025"
     CDS             14531..15268
                     /locus_tag="RPH49_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDY5125154.1"
                     /translation="MTKELERLQKRIANSGYTSRRKAETLISEGKVKVNGTTVTELGT
                     KVKPSDTIEVEGIKIELEDKIYILFHKPTQVITSVSDDRGRTVVTDYFKDIEARIYPV
                     GRLDYDTSGLLLLTNDGEFTNLMTHPRYQIKKKYVAKLKGYLMREEVKALEKGIELED
                     GMTQPAEVKVKKQDKDKNTTLVEITITEGRNRQVRRMFEHFGHQVTKLSRIEYGPLNV
                     VGLNAGEGRVLTPHEVKVMRHLAEHGK"
     gene            15401..16126
                     /gene="srrA"
                     /locus_tag="RPH49_002026"
     CDS             15401..16126
                     /gene="srrA"
                     /locus_tag="RPH49_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator SrrA"
                     /protein_id="HDY5125155.1"
                     /translation="MSNEILIVDDEDRIRRLLKMYLERESFEIHEASNGQEAYELAME
                     NNYACILLDLMLPEMDGIQVATKLREHKQTPIIMLTAKGEETNRVEGFESGADDYIVK
                     PFSPREVVLRVKALLRRTQSTTVEQSEPHARDVIEFKHLEIDNDAHRVLADNQEVNLT
                     PKEYELLIYLAKTPNKVFDREQLLKEVWHYEFYGDLRTVDTHVKRLREKLNRVSSEAA
                     HMIQTVWGVGYKFEVKSNDEPAK"
     gene            16107..17858
                     /gene="srrB"
                     /locus_tag="RPH49_002027"
     CDS             16107..17858
                     /gene="srrB"
                     /locus_tag="RPH49_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     SrrB"
                     /protein_id="HDY5125156.1"
                     /translation="MMSRLNSVVIKLWLTIILIVTTVLILLSIALITFMQYYFTQETE
                     NAIREDARRISSLVEQSHNKEEAIKYSQTLIENPGGLMIINNKHRQSTASLSNIKKQM
                     LNEVVNNDHFDDVFDKGKSVTRNVTIKEKGSSQTYILLGYPTKAQKNSHSKYSGVFIY
                     KDLKSIEDTNNAITIITIITAVIFLTITTVFAFFLSSRITKPLRRLRDQATRVSEGDY
                     SYKPSVTTKDEIGQLSQAFNQMSTEIEEHVDALSTSKNIRDSLINSMVEGVLGINESR
                     QIILSNKMANDIMDNIDEDAKAFLLRQIEDTFKSKQTEMRDLEMNARFFVVTTSYIDK
                     IEQGGKSGVVVTVRDMTNEHNLDQMKKDFIANVSHELRTPISLLQGYTESIVDGIVTE
                     PDEIKESLAIVLDESKRLNRLVNELLNVARMDAEGLSVNKEVQPIAALLDKMKIKYRQ
                     QADDLGLNMTFNYCKKRVWSYDMDRMDQVLTNLIDNASRYTKPGDEIAITCDENKSED
                     ILYIKDTGTGIAPEHLQQVFDRFYKVDAARTRGKQGTGLGLFICKMIIEEHGGSIDVK
                     SELGKGTTFIIKLPKPE"
     gene            18110..19027
                     /locus_tag="RPH49_002028"
     CDS             18110..19027
                     /locus_tag="RPH49_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014373836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1672 domain-containing protein"
                     /protein_id="HDY5125157.1"
                     /translation="MKKFIGSVLTTTLILGGCSMMENESSKDTNTETKSVPEEMEASK
                     YVGQGFQPPAEKDAIEFAKKHKDKIAKRGEQFFMDNFGLKVKATNVVGSGDGVEVYVH
                     CDDHDIVFNASIPFDKSIIDSDSSLRSEDKGDDMSTLVGTVLSGFEYRAQKEKYDNLY
                     KFFKDNEEKYQYTGFTKEAINKTQNSGYENEYFYIVANIPTLQEYRKYYEPLIKKNNL
                     DFKKGMKDARRGVGYKAEIELYTTLFSKSRNFSKDKKLDDAIDLSESVKKLNLNLENT
                     KIFLQLTKSTINTKQVNYSDNKPIKIEVE"
     gene            19030..>20045
                     /locus_tag="RPH49_002029"
     CDS             19030..>20045
                     /locus_tag="RPH49_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125158.1"
                     /translation="MNNINDRDLTELSGYWVYQDIKDGSKFRVNDKKFKQVEEITKVA
                     NKNNSSDIKVYELLDENETPTGKQVLLFQGTDNQKSDVKSNPFRGKVADDWIENIKLM
                     NDKNKSTSLLEQNNAYIKSYEQKLKDADTLKSSDFLRKYKQNPSTYKNKTIKSDGGNS
                     QGGASANHQGLINPNKNIVSTNPAMLPKSIWENFKSQNFENMINYHSKFDILSWLQDP
                     FATPTLGKRVNLETGVPTMDGLVNSHLGYKRKLNPRYNTYKDLAVYKIKSVKDTMIKN
                     GKKVKKTIEIDINMDDRIPINVWTGDSIARTGKGTPIKLNLENLSALSNLVTGETSNM
                     LTDCV"
BASE COUNT         7181 a         2849 c         3623 g         6392 t
ORIGIN      
        1 acctataaaa aattacacaa gtattatcct tgaccttaaa agcatcccga catattttta
       61 agcattttgt gaagtaataa aatatttact gtgttatgat agcatgtact atagagaaat
      121 agaggtatta acttatggaa aagttaaatc aagttatgtt atatgttgat gatgttgaca
      181 aagcgaaagc attttggaca gaaactttag aatttgttgt tgtaagtgaa acaccgttag
      241 ctgaggacta tgttgcagtt gaagtatcac ctacgaaaga tgctgaaacg tcgttgacga
      301 ttatggcaaa agaatttatt gaaaagtata gtccagaggt gaacctagga acaccatctt
      361 taatgtttaa agagaaaaac tttgatgcat tatactcaaa attaaatgat ttaggtttaa
      421 ctgggcatga tatagtagaa atgaatggtc aacgtgcatt taatttccaa gatggccaag
      481 gtaactattt tgcagttagt gactaaacaa tcgattttaa tatttataca aacctttata
      541 ttgattttcg gattgaattt cagtatgaag gttttatttt tatcgtttta tgcaatcgtt
      601 tgcacaaatc ttttgacttt tttagaaagt gtgactaaac tggtattata caatggttgg
      661 aagcgttttc cagcgcagtg attaacagga ggtgattaaa tggttacgat taaagatgtt
      721 gcactaaaag ccggtgtttc tccttcgaca gtttcaaggg ttataaaagg aaatcaacgt
      781 attagcgaag cgacaatttc aaaagtgaag aaagttatgg aagaattgaa ttattttcct
      841 aatactgctg ctagaacttt aattactaac caaacatata aaattggttt agtgttaaaa
      901 gggtctgagg agcctattcg actgaatcca ttctacatca atgtattgct aggaatttct
      961 gaaacgtgta accagcatgg ctatggtaca caaacgacag tctcaaataa tttgaatgat
     1021 ttaatggatg aagtttataa aatgattaaa caacgaatgg ttgatgcgtt tatactgctc
     1081 tattcaaaag aaaatgatcc gattaaacaa atgttaattg atgaaagcat gccatttatt
     1141 gtgattggta agcctacatc ggatatagat catcaattta cacacataga taatgataat
     1201 atattagctt ctgaaaattt gacacgacat gttattgaac aaggtgtaga tgaattaata
     1261 tttattacag aaaaaggaaa ttttgaagtt tcaaaagata gaataaaagg atttgaaacg
     1321 atagcttctc aaaataaaat taattatcaa attattgaga ctagtaatga aagagaagtt
     1381 atttttaatt acatgcaaaa tctacatacg cgtttgaagg acccaaatat taaacaggca
     1441 atcatttcgt tagatgctgt gttacattta gcgattttaa gtgtcctata tgaacttaat
     1501 attgaaattc cgaaagatgt aatgacagca acgttcaatg attcttattt aaccgaaatt
     1561 gcgtcaccac ctcaaaccag tattgacatc gagcctcgaa tgttaggtca acaggctggt
     1621 gcagcaattt taaatatatt aaaaaataaa gcacaggatg ttattgaact cgtcattata
     1681 gatacagaat taaaaataag aaaatcaaca cagcgatagc aaaggagttt taaaatgaat
     1741 aagcaatggt ggaaagaagc agtagcatat caagtatatc caagaagttt taatgatagt
     1801 aatcacgatg gtattgggga tttacctgga atgattgata aattggacta cttaaaagat
     1861 ttaggtatcg atgtcatttg gctcagtcca atgtttaaat cacctaatga tgacaatggt
     1921 tatgatatta gtgactatca agaaattatg gatgaatttg gaacgatgga agactttgat
     1981 cgtttattaa aaggtgttca tgatagaggc atgaagctta ttttagattt agttgtaaat
     2041 catacatctg atgaacatcc ttggtttata gaatctaaat ctagtaaaga caatcccaaa
     2101 cgtgattggt atatttggca agatccaaag ccagatggct ctgaacctaa caactgggaa
     2161 agtatcttta atggatctac atgggaatat gatgctaata ctgagcaata ttatttccat
     2221 ttattcagta aaaaacaacc tgatttgaat tgggctaatc cagaagttag agatgctgta
     2281 tttgaaatga tgaactggtg gtttgataaa ggcattgatg gatttagagt agatgcaatt
     2341 acgcatatta aaaagacgtt tgaagcgggt gacttacctg tacctgagga taaaacatat
     2401 gccccagcat ttgatgtaga tatgaatcag ccaggtatac aaacttggtt acaagagatg
     2461 aaagatcgct cattaagtaa gtatgacatt atgactgttg gtgaagcgaa tggtgtaagc
     2521 cctgatgatg ctgatgactg ggtcggggaa gaaaatggta aatttaatat gatattccaa
     2581 tttgaacatt tgggactgtg gaatagtggt gattctcact ttgatgtaaa ttcgtataaa
     2641 tctgtattaa atagatggca aaaacaactt gaaaataaag gttggaatgc gttgtttatt
     2701 gaaaatcacg accaaccacg acgtgtatcg acgtggggtg acgatgacaa gtattggtat
     2761 gaatcagcaa caagtcatgc agctgtttat ttcttgcaac aaggtacgcc attcatttat
     2821 caaggtcaag aaattggtat gacgaattat ccatttgaaa gtattgaaac gtttaacgat
     2881 gttgctgtta aaaatgacta tcaaattgtg aaagctcaag gtggagatgt agacgcttta
     2941 cttgcgaaat ataaagatga gaaccgagat aattctcgca caccaatgca atgggatgat
     3001 acgttaaatg gaggatttac aaatggtgaa ccgtggttcc cagtgaatcc gaattataaa
     3061 actatcaatg ttgcacaaca attagaagat gagcattcag tattacaatt ttataaagat
     3121 ttaattcaat taagaaagtc taatgatgta tacgtatatg gtcaatttga tttagtagat
     3181 gctgaaaatt cacaagtttt tgcgtacacg agaacattaa atgaaaagca agttcttatt
     3241 gtaggtaatc ttactaacca cgaagcagaa ttaactgtac catttgattt aagccatgga
     3301 gaagtagagc tatttaatta tgatgccaaa gttaatttaa aacagttacg tccatatgaa
     3361 gcatgtgtta tcgaactaaa ttaacatatt aatatgcccc ctaatagaat ctaaggccat
     3421 ttgtagacct atagatatat tagggggctt ctttgttttt aatttttaat cttcgtcata
     3481 aggactctgt ttaacaggaa tccaaagctg aattttagtg aatgggtcat taaatgaaat
     3541 atcgagaggg tacacttcaa catataaatc atttcgttca tatggcaatg ttaactgcaa
     3601 acttgattca atatagtacc aagcttcatt agttgcataa tcaatttcac cttgtaaatt
     3661 gaatttcgca caatgtttgc caggtaaaaa tcggctttct aagtgtgcag gataacgttc
     3721 acttggtaca cctacaaata tttctaaacc attttcaaga ggacaactaa taacaaatag
     3781 ttcaaatgga ctaacgtcat tatatcgtcg taactcttta attttaccat caatgagcaa
     3841 gtcttctaaa aaatccggaa cattaaaagg atgtgacaaa tacttagtgt ctataaatcg
     3901 tgcatatcca accaatgaaa tatcatctgt ctcttctaat ctgtatggat agggtgctct
     3961 ctcagtagtt gataatttga tatataatcg ctcttgaatt tgtaattcat cttttttagt
     4021 agaagcttga ataggtgata cgccgtgaaa atcactaaaa tcatttgcaa aatcatttga
     4081 atttgcatag tgatattttt tagcgatatc tacaagtcgt gtagcaccat taatcacatc
     4141 atttgcagcg agtgtcattt tacgcgcgcg tgcataagct tctggagata agccgacaat
     4201 cattttaaat gattgatcaa gatggtatgg cgaaagacca acgtaatcac ttaattcttg
     4261 caaattgaaa ggctctaata aacgatcttc aatataaaca attgcctgtt gtatttgctt
     4321 gataacgtcc aaaactttca ctccaattaa ttcaatcatt tatttttatt ctacattatt
     4381 tctataaatt atacacccat ttgttcaatg attattaaaa tagttttggg cattgtaaaa
     4441 tataatttca taatatagtc tagaaaaaaa gcgaatgata gaacaattga tttacttgat
     4501 tcgtaatcaa tccttgtcat tcgctcattt atttttgttt aacatgtgcg ttttaattca
     4561 attattgaat atcgtcccac caatggttac catcacgagc aagtagtaaa tcactttcta
     4621 atggaccatt agtacctgat tcatagttag ggaattctgg atcaaccata ttccattcat
     4681 cttgaattgc atcaacaaat ttccatgttg attttaattc ttcccagtgc gtgaagttag
     4741 tggcatcacc tttaagacaa tcgaataata gattttcata tgcatctaca gtattcattt
     4801 tatcttgagc gctcattgaa taagacaatt gaacaggttc agtttcgata ccttgtgtat
     4861 ttttcttagc atttagatgt aaagatacac cttcattagg ttggatattg attactaata
     4921 ggtttgaatc taataattta tcagtttcat agtataagtt cattggtact tctttaaatt
     4981 caacgacaac ttgaattgtt ttagatttca tacgtttacc agtacgaata tagaatggta
     5041 caccagccca tctaaagtta tcaattgtta atttacctga aacaaaggta ggtgtgttag
     5101 agtcatctgc aacgcgatct tcatcacggt atgctttaac ttgtttacca tcgatatagc
     5161 cttcgccata ttgaccacga acaaagttct ttttaacatc ttcagattgg aaatgacgca
     5221 gtgatttaag tacttttact ttctcagcac ggatatcttc actatttaaa ctaataggtg
     5281 cttccatagc taataatgca accatttgta acatgtggtt ttgcaccata tcttttagcg
     5341 cgccacttga ttcataataa ccaccacgat cttcaacacc tagtatttca gaagatgtaa
     5401 cttggatgtt tgaaatatat ttgttattcc ataatggttc aaacatcgca ttcgcaaaac
     5461 gtaatacctc gatattttga accatgtctt ttcctaaata gtggtcaata cgataaattt
     5521 cttcttcttt aaatgattta cgaatttgat tgtttaatgc ttcggctgat tttaaatcac
     5581 taccgaatgg tttttcgata acaaggcgtt taaatccttt tgtatcagta agaccagaag
     5641 attttagata atcagaaata acgccaaaga attgtggtgc cattgctaaa tagaatagtc
     5701 gattaccttt taattcaaat tggctgtcta attcattact aaaatctaat aattcttgat
     5761 agctttcttc attactaaca tcatgtctat gatagaagac atgttccata aacgcgtcaa
     5821 ttttgtttgt atcttttacg tgcttttgaa ttgatgattt tacttgatta cggaaatcat
     5881 cattagtaat gtcacgacgt ccaataccga tgatggcaat atgttcatct aaattgtctt
     5941 gttggtagag atggaatatt gatggaaaca acttacgatg gcttaagtca ccagttgcac
     6001 caaagattgt gattaaacaa gggatgtgtt tgtttttagt actcaagatt aaaacctcaa
     6061 ttcttaatta gatatatgat ttattattat aagataatcc attcagcagg tcattcaata
     6121 tgctcgacag tatgcagtgt cttaaatgaa atatcgattc atgtatcatg tttaatgtga
     6181 tacttattaa tgataagtat aacgtaatta tcaaaattta tatagttttg tctacgttaa
     6241 agttagaaaa attaactagc aaagacgaat ttttaacaga ttttgattca agtataaatt
     6301 aaaactaaat tgatacaaat tttatgataa aatgaattga agaaaaggag gggcatatat
     6361 ggaagttaca ttttttggaa cgagtgcagg tttgcctaca aaagagagaa atacacaagc
     6421 aatcgcctta aatttagaac catattccaa ttccatatgg cttttcgacg ttggtgaagg
     6481 tacacagcac caaattttac atcatgcaat taaattagga aaagtgacac atatatttat
     6541 tactcatatg catggcgatc atatttttgg tttgccagga ttactttcta gtcgttcttt
     6601 tcagggcggt gaacagaagc cgcttacatt ggttggacca aaaggaatta aagcatatgt
     6661 ggaaatgtct atgaatttat cagagtcaca tttaaactat ccaattacat atattgaaat
     6721 cgatgatcat ctgacatatc atcatgatgg ttttactgta gaggcgcatt tacttaatca
     6781 tggtattcca tcatatggat atagagtaat ggcacctgaa actacaggta caatcaatgt
     6841 tgaagcgtta aaaaacattg gtcttgaacc aggtcctaaa tatcaagaag taaaatctca
     6901 tgatacattt gaacataatg gtcaagttta tcaatcaaaa gattttagag gtgagtccaa
     6961 acagggtcca gttgtagcaa tttttggtga tacaaaacca tgttctaatg aacgtgtgat
     7021 ttctagagat gctgatgtga tggtacatga agcgacctat atagatggtg aaaagcattt
     7081 agccaacaat tatcatcata gccatattga agacgtattt gcattgataa aagaagccaa
     7141 tgttaaacgt acgttgatta cacatttgag caatcgctat aatacagaag atataaatga
     7201 aatttatcaa acattgatac aaaatgaaga tacacctaat tttaattttg taaaagattt
     7261 tgatagtttt aaagtctaat gacaaagtaa taaacaatgc ttgccaaata gtaataattt
     7321 ataaaaataa cccgtccaac tatgtatgcg atgatgcata catgtgttgg cgggtttgtt
     7381 tttattggtc ttctatatta gaaagttcaa tactacggtc gacggcagcg tttagacaat
     7441 cttcgaaaat agatactaaa tcatattgtg acaatgtatc aaggccagct tgtgtcgtac
     7501 cacctttaga ggtaatattt tttcttaatt gagccatgct caaatctgaa cgttcaatca
     7561 tcttacttgt acctataata aggttgcgta tagattcttc aacttgttct ttttctagac
     7621 caagtttcgt accagcttta acgtattgct cgaatacatg atataaaaat gctgggccgc
     7681 ttccggtgat agctgttact tgatgtaaat gatcttctga tacttcaatt acagaaccaa
     7741 atgctttaac taaatcgtta atttcatctt tagatttagg gtcaaagttg tttgaaaaac
     7801 taatgccagt aacagagtgt ccgacttgcg catttgtgtt tggcataatt ctagcaactg
     7861 gattttggca ttctaattgt tgtttaatat aatcaatcgg aatacctgcc ataattgaaa
     7921 tgaagcaatt gtcttttgtg atatgtggtt tgatgcgtgt tgctagagca tcaaagtcat
     7981 gcggtttggt acctaaaaaa acataatctg catcttttaa taatgtcgca tcatcataac
     8041 tatagttaac acctagtttt tcagcgaatg cttttaaagc ttgttcatta gatttatttg
     8101 ttaaatatat atcattggca tctaagttgc ttgagttaat aattcctgta aatatagctt
     8161 gtgccatatt accagctcca taaaatacga gtttcattaa cgtcacatcc ctttagtttt
     8221 tgatttgtat gttatatttt cttattattg tatatatatt aggaaagata atcaacttgt
     8281 ctcaattatg taaagttgat aaattgcatt ctatataatt gaaaagggag gttaattgat
     8341 gaaaggacaa cattttatag tgactggtgg tacgagtggt ttaggtttat cgattgtccg
     8401 aaagttactt gaaaataaag tgcatgtaac gttgttggtg cgtgatgttg ataaagcaac
     8461 tagaatcttt gaacaagaat tggggaaaac tataaatgtt attccttgtg acttaaatga
     8521 tttgaagtcg atacaggcac tgcaatttga agacaataca tcattcgatg gattcattta
     8581 tagtgcaggt ttaggttatt tcaaatctat ttcagaccat agtttttcag aaatgattga
     8641 aacgtatcag cttaatttaa ttagttttaa tgttttatat actgtgttga gaccatattt
     8701 aacatctaac gcacatattg taggtatttc aagtcaagct gcattttcca ctcaagcaaa
     8761 tgctgcacat tatggggcat cgaaagcagg gttttatgca ttaatgaatg ctttaagact
     8821 agagtcacca aacatacata tcatgacagt taatgttggc ccgattgata caccttttca
     8881 tcaaaaagcc gatccatcaa tgaagtatgc taaaaagatg gggaaaatta tgcttgatgc
     8941 taatcagctt gcagaagata tcatttatgg cattaaaaca aaacaattgg aaattaatcg
     9001 ccctaaatgg atgcaccatg cgttgaaaat gtatcaaatt gcgcctagat tttttgaacg
     9061 atgttttcct aaattattta aaaataaagc ataaataggt gggatggcaa tgaactgtca
     9121 atcggagagt gtggtaagac tttgtgtacg atatgcggaa caactatcag tgtttgaaga
     9181 atttacagtg ctggatattt taggcgatat ttctgtagac caaatttcag acagtacatt
     9241 atattatact tgtgaaaaat tcaaactact tgtgttgcaa ggaaatgtgc tgggtgtaca
     9301 aataataact aataatgatg aatcaacatg cgaagtgaaa tatagaaaga tgttttaata
     9361 aaattattaa aagatgaagt gggagaagtt tgcttaaggc actgccgcag ggcgaaatta
     9421 ctaaatactg atgcgtgagg acaacgcttt aatttctatc ataagtgagt aatcttaatc
     9481 ataaattata gcgaattgta cataaacaac agcagtaagg catttttata atgaaacgcc
     9541 tcatgctgct gtttttatta ctgaaaatga cttctacact aaatgattgg tatattccaa
     9601 atcctttaca cgagctcttg ctgttttaat ctgatctaaa ctaactttag tatgatagtt
     9661 ttcaatattt tcttttaatt ggtcgacgct acttgcacct acaatgatgg aaccaagcac
     9721 gtcatgtgat gttaaataac taaatgtcaa tgcagataaa ttactttcaa tttctttaat
     9781 agaggctatt gtttcaccca attcatcatg agaataatca aaaataccat ctttaaattt
     9841 attgtctagc acattaacac tgtttgaagt taataatcct ttagacacag gtcctcttgc
     9901 caatacttta acatcattgt tgtgaattgc atctaataat gattctggac gattatcaat
     9961 caaattgaat tgagacatta tcgtttcgat ttgactatgt tttaaataat aatcaattac
    10021 atttgggcga atagaagaaa taccgtaagc acgtataatt ccttcttgtt tcaattcatc
    10081 aaatgcgctt attgtttcgt ctaatgggtc atcaatggtt ccgccatgaa gttgatataa
    10141 atcgatatga tcgataccta aacgctttag tgaaccttta actgcctctt taatatagga
    10201 tttactcgga tcccatgttg tactgccatc ttttgttaaa cgattgccta cttttgtacc
    10261 aatgacaata tcatcgcgtt gttgatattt aagaagtgcc ttaccaacaa ctgattcatt
    10321 tataccttta tcgtacatat ctgctgtatc aaaataagtg ataccatttt caacagcaca
    10381 atctataatt tgttcggctt tttttaaatc tgtacctaaa ctcatgcaac ctagacctaa
    10441 ttcagataat gaaataccac tttttaatat atttttttgc atgtctgttc tcctttcgat
    10501 acactttagc taacaagcat agtgtatcaa tatataatat gaatttaaag gaacgtgatt
    10561 ataatggatt taaatgaaaa aacaattgat cgaacagtta tttataatgg caaaattgta
    10621 gatgtagaaa ttcatacagt gacattacca aacggtgaaa cgtcaacaag agaattagtt
    10681 tatcataatg gtgcagttgc tgtttgtgca gtgacaccta aaaaagaagt cgtattagtg
    10741 aaacagtatc gtaaaccagt agaaaaacca ttgctagaaa ttccagctgg taaattagaa
    10801 gatgatgaag atagagtcga agcggcaaaa cgtgaattag aagaagaaac aggatatatt
    10861 gccaaagagt taacacatgt tgtagatatg tatggttcac caggtttttg cgatgaacaa
    10921 ttatcaatat attttacgga taatttagaa gaaggtacag ttcacttaga tgaagatgaa
    10981 tttgtcgaag tcattaaagt tccgattgag aatgttaaat cgatgctaat gaataaagaa
    11041 atagaagatg cgaagactat cattgcattg caacacctat tattaaatta taatcattct
    11101 aaataacaaa tgagaaaagc ttgcatttta ttgagaaaac tgttagtttt aattgtgaag
    11161 tttgaaataa tttgtaatga ttttaattat tagtagggga gtggacatcg ttggaagaac
    11221 gattaaatcg cgttaagcaa caattacaac aatcatcata taagctaacg ccacaacgcg
    11281 aagctactgt tagagttcta attgaaaatg aaaaagatca tctaagtgct gaagacgtat
    11341 atctgaaagt aaaagataaa gcgcctgaaa ttggcttggc gacagtatac agaacgttag
    11401 agttgttagc tgaactaaaa gttgtcgaca aaattaactt tggtgatggc gtcgctcgtt
    11461 ttgatttaag aaaagaaggc gcaaaacatt tccaccatca tttagtatgt atggaatgtg
    11521 gtcgtgtaga tgaaatcgat gaagatttgt taccagaagt tgaaaatcga gttgaaaatg
    11581 agttcaattt taaaatttta gatcatcgtt taactttcca tggtgtgtgt gaaacgtgcc
    11641 aagctaaagg taaaggatag taaattgcgt aggttaaatt aaccttcgct ttttttagag
    11701 gtgtggttat ggaaacaatt attgaagaat atttgcgttt tatacaaatt gaaaaaggac
    11761 taagttctaa cacaattggt gcttatagac gtgatttgaa aaagtatcaa gattatatga
    11821 ctgaacatca tatctcgcat attgatttta tagatcgaca attaattcaa gagtgtttgg
    11881 ggcatttaat agaccaaggg caatctgcta aatctattgc gcgatttatt tcaacaatcc
    11941 gtagttttca tcaatttgct ataagagaaa aatatgcggc gaaagatcca acggtattat
    12001 tagattcacc aaaatatgac aaaaaattgc ctgacgtttt aaatgttgac gaagtgttgg
    12061 ctttattaga aacgccggat ctaaataaaa ttaatggtta tcgtgatcgt acgatgttag
    12121 aacttctgta cgcaacggga atgcgtgtat ctgaattgat acatttagag ttagagaacg
    12181 tgaacttaat aatgggattt gtacgcgtat ttggtaaagg cgataaagaa agaattgtac
    12241 cattaggcga cgcagtcatt gagtacttaa ctacttatat tgaaacgatt agaccgcaac
    12301 ttttaaaaaa gactattacc gaagtcttat ttttaaatat gcatggtaaa cctttatcgc
    12361 gacaagcaat atggaaaatg attaaacaaa atggtgtaaa ggcaaacatt aaaaagacgt
    12421 taacgccaca tacgttacgc cactcttttg cgacacattt attggaaaat ggcgcagatt
    12481 taagagcagt gcaagagatg ttaggtcact ctgacatatc tactacccaa ctctatacac
    12541 atgtttcgaa atctcaaatt agaaaaatgt ataaccaatt tcatcctaga gcataaagtg
    12601 aacaataact caaaagtcac aatacatatg actaaaaatg tctgtgctat tgtggctttt
    12661 ttaaattggt tgattaatta cgtctatgtt ttcttaattg aatcgcttct tcttttgctg
    12721 caatcacttc tgaacgatca cggcgcatgt gatggtctac aataaaagga tctgttgctg
    12781 tttcctgatt ataatcatag tctggatagt tggccttgat gatgcgttca aagactggag
    12841 ttattggtaa tataacagat gaaaaaggct ttgctgcatt caattttgca atctgttgct
    12901 caattaacaa ctgataatca tttaaattaa ggtataacgc atctctgtct ttagcatttt
    12961 gtattatttc tttagattta ttaaaagact tataggcgcc ttttaaatta ttgcggcgat
    13021 aatggtaaca agcagttgca aacaagatta aactaacaac tgcatcttgc ttactgtagt
    13081 tattttcagc tttccatgca tcttctaaaa tgtcatgaca taggaaataa tgttgcttag
    13141 tatgaaattg ataatagaaa tttatcagtg cctgttgcat tttgttatca ccccaattta
    13201 aaagtaagtt attttcatgc tataatattt tagagaatta tgcacatatg acgcaatacg
    13261 aggtagatat tatgtatgaa gttaaattag atgctttcaa tggaccatta gatttattgc
    13321 tgcatcttat ccaaaaattt gaaatagata tttatgatat tcctatgcaa gcattaacag
    13381 agcagtatat gcagtacgtt catgcaatga aacagcttga aattaatatt gcaagtgaat
    13441 acctagtatt agcgtcagaa ctcttaatga ttaaaagtaa gatgctatta ccacaatcaa
    13501 catcagatat ggatgttgat gatgacccac gggaagattt agttgggcgt ttaatagaat
    13561 atcaaaatta taaagaatat actgctattt taaatgacat gaaagaagaa agagattttt
    13621 attttacaaa aagaccgaca gatttatctc atttggaaac agatgaatct tgggatccaa
    13681 atcatacgat tgatttaact gaattaattg tagcttatca aagagttaaa aatagagttg
    13741 agttaaatac acctaaatct gttgaaatcc gaaaagagac atttaccatt caacaagcta
    13801 cagaacaagt gacatcgaga ttgaaagata aagatcattt taacttcttt agtctgttta
    13861 cgttttctga gccaattgaa caagtagtca ctcacttttt agctatttta gagatgtcaa
    13921 aagcaggaat aattaatatt gagcaacaac gtaattttga agatattaac attattagag
    13981 gagtgaacta ccattttgga taatcatggt atattagagt cgcttttatt tacagctggc
    14041 gatgaaggtt tagatgaaaa acaactatta gaaatattag atatgtcgaa agaccaactc
    14101 gttgaattaa ttgaaaatta ttcatcacat ggattaatga tacaacgatt tggaacgacg
    14161 tatgttttaa cgactaaaaa agaagcggca acgtatattg aacaattaat tgaacaaaag
    14221 tcacaaatga aattatcaca agcagcaatg gaagtactat caattattgc ttataaccag
    14281 ccattatcaa gaagtgatat tgaattaatt cgtagtatca attcagatgg tgcggtcaag
    14341 actttgattg ccaaaggact agttgaggct aaagtggtta atgaacagcg tagccaacag
    14401 ttaattacta ctgatttatt tttaaatgta tttggtattt ccaatataga agatttgccg
    14461 acaactgaag aagacgatga agaaatggat gctttcttca gtaatctagt caatcaaaaa
    14521 ggagaaaata atgactaaag aattagaacg attacaaaaa cgtatagcta atagcggtta
    14581 tacttcaaga cgtaaggcag aaactttaat ttctgaagga aaagtgaaag tgaatggtac
    14641 gactgtcact gaattaggaa caaaagtaaa gccatcagat acgattgaag ttgaaggtat
    14701 taaaatagaa ctagaagaca aaatttacat tttattccat aaaccaactc aagtgataac
    14761 aagtgtatca gatgatagag gacgtacagt ggttacggat tactttaaag atatagaagc
    14821 acgtatttat cctgttggtc gtttagacta tgatacttct ggattgttat tacttacaaa
    14881 tgatggtgaa tttactaatt taatgacaca tccaagatat caaattaaga agaaatatgt
    14941 agcaaaatta aaaggttact taatgagaga agaagtgaaa gccctagaaa aaggtattga
    15001 attagaagat ggtatgacgc aaccggctga agtgaaagtt aagaaacaag ataaagataa
    15061 aaacacaaca ttggttgaaa ttacaattac agaaggtcgt aatcgccaag tcagaagaat
    15121 gttcgaacat tttggtcatc aagtgacgaa actgtctcgt attgaatatg ggcctttaaa
    15181 tgttgtcggt ttgaatgctg gtgaaggacg tgtattgacg cctcatgaag taaaagtgat
    15241 gcgtcattta gcagaacatg ggaaataatt aaataaaata tgtatttatc acaaagtttg
    15301 agaatttttt cacaaaattt taggttttta ataactgtat gcgctttcct gtgatataat
    15361 acttttgtaa agaaaagcat gtgtgggagg tatgacctgt atgtcgaacg aaatacttat
    15421 cgtagatgat gaggatagaa tcagaagatt acttaaaatg tatttagaaa gagaatcttt
    15481 tgaaatccat gaagcaagta atggccaaga ggcttatgaa cttgcaatgg agaataatta
    15541 tgcttgcata ctactagatt taatgttgcc tgaaatggat ggtatccagg tggcaactaa
    15601 attgcgtgaa cataaacaaa caccgattat tatgttgact gctaaaggtg aagaaacaaa
    15661 ccgtgttgaa ggttttgaat ctggtgcaga tgattatatc gtcaaaccat tttcaccaag
    15721 agaagtagtc ttaagagtta aagcacttct aagaagaacg caatctacaa ctgtagaaca
    15781 aagcgaacct cacgcacgtg atgtgattga atttaaacat ttagaaatag ataatgatgc
    15841 acatcgcgta cttgctgata atcaagaagt taatttgact cctaaagagt acgaattatt
    15901 aatatattta gctaaaacac caaataaagt atttgaccgt gaacaattat taaaagaagt
    15961 ttggcattat gaattctatg gtgatttaag aacagttgat actcatgtta aacgacttag
    16021 agaaaagtta aatcgtgtgt ctagcgaagc tgcgcatatg attcaaacag tctggggcgt
    16081 tgggtataaa tttgaggtta aatctaatga tgagccggct aaatagtgtc gtaattaaac
    16141 tgtggttaac tattatttta atagtgacga cagttttaat tttattaagt attgctttaa
    16201 ttacctttat gcaatactat ttcacacaag aaactgaaaa tgccataaga gaagatgcta
    16261 gacgtataag ttcactggtc gaacaatcac ataataaaga agaagcaata aaatatagtc
    16321 aaacattaat tgaaaatcct ggtgggttga tgattataaa caataaacat cgtcaatcaa
    16381 cggcttcact ttctaatatt aaaaagcaaa tgttgaatga agtagtcaac aacgaccatt
    16441 ttgacgatgt gtttgataaa ggtaaatctg ttactcgaaa tgtaacgatt aaagaaaagg
    16501 gttcatctca aacttatatt ttgttaggct atccaacaaa agcacagaag aatagtcata
    16561 gcaaatatag tggagtattt atatataaag acttgaaatc aatcgaagat acaaataatg
    16621 ctattacgat tatcactata attacggctg ttattttctt aacaattaca acagtctttg
    16681 cgtttttctt atcgtcaaga attacaaaac ctttaagacg tttaagagac caagctacac
    16741 gtgtatctga aggggattac tcttataaac cttctgtcac aacgaaagat gaaattggtc
    16801 aattatcgca ggcatttaat cagatgagta cagaaatcga agagcatgtc gacgcattat
    16861 ccacatctaa aaatattaga gacagcttaa ttaactctat ggtagaaggc gtcctaggta
    16921 ttaatgagag tcgacaaatt atcttatcta ataagatggc gaatgatatt atggacaata
    16981 ttgatgaaga tgctaaagct ttcttattaa gacaaataga agatactttt aaatcaaaac
    17041 aaactgaaat gcgcgattta gaaatgaatg cacgattctt tgttgtgact acaagctata
    17101 tcgacaagat tgaacaggga ggtaaaagtg gtgttgttgt gacagttcgt gatatgacta
    17161 atgagcacaa tctagatcaa atgaagaaag atttcattgc taatgtatca catgaattac
    17221 gtacaccgat atcattactt caaggttata ctgaatcaat tgtagatggt attgttacag
    17281 aaccggatga aataaaagaa tcgcttgcca ttgtccttga tgaatcgaaa cgtttaaatc
    17341 gtttagttaa tgaattgtta aatgttgctc gcatggatgc tgaagggtta tccgtaaata
    17401 aagaagttca gcctattgca gcgttactag ataagatgaa aattaagtat cgccaacaag
    17461 ctgatgattt aggtctaaat atgactttta attattgtaa gaagcgtgtt tggagttatg
    17521 atatggatcg catggaccaa gtactaacga acttaattga taatgcatca cgttatacga
    17581 aacctggaga tgaaattgca attacttgtg atgaaaataa aagcgaagat attttataca
    17641 ttaaagatac aggcacgggc attgcaccag aacatttaca acaagtattt gatcgttttt
    17701 ataaagttga tgcagcgaga acgcgaggta aacaaggtac cggtttaggt ttgttcattt
    17761 gtaaaatgat tatcgaagag catggtggtt ccattgatgt taaaagcgaa ttaggaaaag
    17821 gcacaacatt tattattaaa ctaccaaaac cagaataaaa ctgaatatag ttatttaaga
    17881 acgcatgtta ttgattagag attctaattt atagcatgcg ttttttgatt gaagtgggga
    17941 attttgtaag tgaattagga aataggattt atgatttttg cgaataacaa ctattaaata
    18001 tattactaat ttatacaaaa atataaagtt tgataaagtt atttatttga ttataaaaat
    18061 agggtaaaat atagatatat tgtaataatt aaattattcg aggtgtcata tgaaaaagtt
    18121 cattggatca gttttaacca cgacattaat tttaggggga tgttccatga tggaaaatga
    18181 atcaagtaaa gacacgaata cagaaacaaa atcagtacca gaagaaatgg aagcttcaaa
    18241 atatgtagga caaggcttcc aaccacctgc agaaaaagat gcgattgaat ttgcgaagaa
    18301 gcataaagat aaaattgcca aacgaggcga acaatttttt atggataact tcggtctaaa
    18361 agttaaagct accaatgttg taggtagtgg cgacggtgta gaagtttatg tgcattgcga
    18421 tgaccacgat atcgtattta atgcgagtat tccatttgat aaatcaatta ttgacagtga
    18481 tagctcatta agaagtgagg ataagggcga tgatatgagt actttagttg gtacagtact
    18541 aagtggattt gaatatcgag cacaaaaaga aaagtatgat aacctatata aatttttcaa
    18601 agataacgaa gagaaatacc aatatacagg atttacaaaa gaggcaatta acaagacaca
    18661 aaatagtgga tatgaaaatg aatattttta tatcgttgca aatataccaa cacttcaaga
    18721 atatagaaaa tattacgaac ctctgattaa aaaaaataat ctagatttta aaaaaggtat
    18781 gaaagatgct agaagaggag taggctacaa agctgaaatc gaattatata caacactgtt
    18841 ttcgaaaagt agaaactttt caaaggacaa gaaattagat gatgctatag atttatccga
    18901 aagcgtgaaa aagttaaacc ttaatttaga aaacacgaaa atatttttac aactaacgaa
    18961 atctaccatt aatactaaac aagtaaatta tagtgataac aaacctatca agattgaggt
    19021 tgagtgaaaa tgaacaatat aaacgataga gatttaactg agttaagtgg ttattgggtt
    19081 taccaagata ttaaagatgg tagtaaattt agagttaacg ataaaaaatt caaacaagtc
    19141 gaagagataa cgaaagtagc taataaaaat aatagttcag atataaaagt ttatgaacta
    19201 ttggatgaaa atgaaacacc tacaggcaaa caagtattat tatttcaagg tacagataac
    19261 caaaagagtg atgtgaaaag caatcctttt cgtgggaagg ttgctgatga ttggattgaa
    19321 aatataaagt taatgaatga taaaaataag tcaacttctt tattagaaca aaataatgct
    19381 tatattaaat cgtatgaaca gaaactaaaa gatgcagata cacttaaaag ctctgatttt
    19441 ttaaggaaat ataagcaaaa tccgtctacg tataaaaaca aaactattaa gtctgatgga
    19501 ggcaattctc aagggggagc aagtgctaac caccaagggt tgattaaccc gaataaaaat
    19561 atagtttcta caaaccctgc catgttacca aagtcaatat gggaaaattt caaatctcaa
    19621 aactttgaaa atatgattaa ttatcatagt aagtttgata ttttatcttg gctgcaggat
    19681 ccatttgcca ctccgacact aggaaaacga gtgaatttag aaactggtgt gccaacgatg
    19741 gatggattag taaatagtca tttaggttat aaaagaaaat taaatccaag atataatact
    19801 tataaagatt tagcagttta taaaattaaa tcagttaaag atactatgat taaaaatggt
    19861 aaaaaagtca aaaaaactat tgaaatcgat ataaatatgg atgatagaat tccaattaat
    19921 gtgtggacag gagattcaat agcgagaacg ggtaaaggga ctcctataaa attaaatcta
    19981 gaaaatctta gtgcattaag taatttggta actggtgaaa caagtaatat gttaaccgat
    20041 tgtgt
//
LOCUS       DAPSKH010000053        18638 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPSKH010000053 DAPSKH010000000
VERSION     DAPSKH010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 18638)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18638)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18638
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.053"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(58..339)
                     /locus_tag="RPH49_002030"
     CDS             complement(58..339)
                     /locus_tag="RPH49_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDY5125159.1"
                     /translation="MTYHERVLALRAESKRTAFDFRFEDLFSKEEWLSMSLAERQKAE
                     KAFRHEVKNMDDVRMPFSSVHDAQVKLYNVVYSYNGIKRNFKQVENEGF"
     gene            628..1323
                     /locus_tag="RPH49_002031"
     CDS             628..1323
                     /locus_tag="RPH49_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5125160.1"
                     /translation="MTVLTDKVAVVTGAGSGIGEAIATLLHEEGVKVILAGRNKDKLQ
                     NVANQLAQDSVKVVPTDVTKKEEVDELIKIAQQTFGGLDIVINSAGQMLSSKITDYQV
                     DEWDSMIDVNIKGTLYTAQAALPTMLEQSSGHLINIASISGFEVTKSSTIYSATKAAV
                     HTITQGLEKELAKTGVKVTSISPGMVDTAITAAYNPTDRKKLEPQDIAEAVLYALTQP
                     KHVNVNEITVRPV"
     gene            1575..1997
                     /locus_tag="RPH49_002032"
     CDS             1575..1997
                     /locus_tag="RPH49_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5125161.1"
                     /translation="MTKKHVFIIIGVILCICIVATVIYLKVKYDEKEKQKSIYYKEQQ
                     ERITLYLKHNTKEPNTIKSVHFTSLKTGPMGDAVIEGYINENKEDNFVAYGSPEHNYQ
                     FGGSLIKSKNLSTLLKPAHQTKTPDDIKKELDSKKNDR"
     gene            2264..2683
                     /locus_tag="RPH49_002033"
     CDS             2264..2683
                     /locus_tag="RPH49_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5125162.1"
                     /translation="MSKKKILILTSIMLIILISVASIYFKMKYDEKEKQKSIYYKEQQ
                     ARITLYLKHNTKEPNTIKSVHFTKLETSPMGSAVIEGYINENKKDDFVAYASPENNFQ
                     FVGDLIKSERLSELLKPAHQLKSPDGIKKELNKKKSH"
     gene            2701..3126
                     /locus_tag="RPH49_002034"
     CDS             2701..3126
                     /locus_tag="RPH49_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5125163.1"
                     /translation="MSKKHGFIIIGVILCICIVASVIYLKMKYDEKEKQKEIYYKGQQ
                     ERITLYLKHNTKEPNTIKSVHFTSLKRGPMGDAVIEGYINENKEADFVAYGSPEENYQ
                     FTGGLTGSNEVLGKLKNAENLKSPEKIKEEINKKKNTKQ"
     gene            3579..4001
                     /locus_tag="RPH49_002035"
     CDS             3579..4001
                     /locus_tag="RPH49_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDY5125164.1"
                     /translation="MPYNYKKQNGELMSVMSQGEKFIHQSPVNDELSALIKLLISKIN
                     GCHYCVDIHKKELKELGVTQMKIDEVLSFRHLDLFTDQEKVTLEFAEMLNSIKDFKKF
                     EIIDRLKSFYDEEQIIDLVFVVNQINGWNRLNIISDKL"
     gene            complement(4113..5651)
                     /locus_tag="RPH49_002036"
     CDS             complement(4113..5651)
                     /locus_tag="RPH49_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbgT family transporter"
                     /protein_id="HDY5125165.1"
                     /translation="MTSKHQQKGSIVNRFLNSVEKIGNKLPDPSVLFFLMCIGLAIMT
                     WVISLFNVSVKHPGTHQTIYIKNIISHDGFTMIMNDTIKNFSEFPALGLVLAVMIGIG
                     VAEKTGYFDKLMISVVNRAPRFLILPTIILIGILGSTAGDAATIILPPLAAMLFIKIG
                     YHPIAGLTMAYASAVGGFAANIVVGMQDALVYSFTEPATRIVSDSIKTNVAMNWYFIA
                     ASVVVLLPTILLVTTKLIIPRLGKYDDSLMHDDHEETSSHITDKEAHALKWANISFIV
                     TIILLIITAIPEHSFLRNAKTGSLLDDAPLINGVGLIILVVFLVPGLVYGILSKEIKN
                     TKDLGKMFGDAVGSMGTFIVIVFFAAQLLAYLKWSNLGIIAAVKGAKLLEHQNGIVLI
                     LGIIVLSAMVNMLIGSASAKWGILGPIFVPMLILIGFHPAFTQVIYRVGDSITNPITP
                     MMPYLPLLLTYAQKYDKRMKLGALLSSLMPYSIALSIVWTVFVIIWFLLGIPVGPGGP
                     IFVK"
     gene            5886..6704
                     /locus_tag="RPH49_002037"
     CDS             5886..6704
                     /locus_tag="RPH49_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001620216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDY5125166.1"
                     /translation="MKRLENKVAVVTGASTGIGQASAIALAQEGAYVLAVDIAEAVSE
                     TVDKIKSNGDNAKAYNVDISDEQQVVDFVSDIKEQFGRIDVLFNNAGVDDASGRIHEY
                     PIDVYDKIMNVDMRGTFLMTKMMLPLMMNQGGSIVNTSSFSGQAADLYRSGYNAAKGA
                     VINFTKSIAIEYGRDGIRSNAIAPGTIETPLVDKLTGTSEDDAGKTFRENQKWMTPLG
                     RLGKPEEVGKLVVFLASDDSSFITGETIRIDGGVMAYTWPGEMLSDDSWKRTLE"
     gene            6968..7333
                     /locus_tag="RPH49_002038"
     CDS             6968..7333
                     /locus_tag="RPH49_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125167.1"
                     /translation="MLKEKESFRLLYQAIREIADKIGDNQLETNSVSLLLLDFDFEHE
                     VFDELYLAILKYLNTVSIENISHSELLNLIENTIPEDREINTFVKNKIIIGFANNYFP
                     ELQVLANEIKSDMASSLKQ"
     gene            8212..9033
                     /gene="cntK"
                     /locus_tag="RPH49_002039"
     CDS             8212..9033
                     /gene="cntK"
                     /locus_tag="RPH49_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine racemase CntK"
                     /protein_id="HDY5125168.1"
                     /translation="MNRQVIEFSKYNPSGNMTILVHSKHDASEYASIANQLMAATHVC
                     CEQVGFIESTQNDDGNDFHLVMSGNEFCGNATMSYIHHLQESHLLKDQQFKVKVSGCS
                     DLVQCAIHDCQYYEVQMPQAHRVVPTTINMGNHSWKAIEIIYETYVHYVIPVKQVTTE
                     IQHLVESYVRKQQWNHKYKTVGMMLFDEQRQFLQPLIYIPEIQSLIWENSCGSGTASI
                     GVFNNYQRNDACKDFTVHQPGGSILVTSKRCHQLGYQTSIKGQVTTVATGKAYIE"
     gene            9044..9862
                     /gene="cntL"
                     /locus_tag="RPH49_002040"
     CDS             9044..9862
                     /gene="cntL"
                     /locus_tag="RPH49_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-histidine (S)-2-aminobutanoyltransferase CntL"
                     /protein_id="HDY5125169.1"
                     /translation="MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYS
                     EFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYF
                     DNIEHCIDEEFGQCSIASNDKLLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLG
                     RRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVV
                     AMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV"
     gene            9855..11156
                     /gene="cntM"
                     /locus_tag="RPH49_002041"
     CDS             9855..11156
                     /gene="cntM"
                     /locus_tag="RPH49_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_096659686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylopine dehydrogenase CntM"
                     /protein_id="HDY5125170.1"
                     /translation="MSKLLMIGTGPVAIQLANICYLKSDYEIDMVGRASTSEKSKRLY
                     QAYKKEKQFEVKIQNEAHQHLEGNFEINRLYKDVKNVKGEYETVVMACTADAYYDTLQ
                     QLSLETLQSVKHVILISPTFGSQMIVEQFMSKFNKDIEVISFSTYLGDTRIVDKEAPN
                     HVLTTGVKKKLYMGSTHSNSTMCQRISALAEQLKIQLEVVESPLHAETRNSSLYVHPP
                     LFMNDFSLKAIFEGTDVPVYVYKLFPEGPITMTLIREMRLMWKEMMAILQAFRVPSVN
                     LIQFMVKENYPVRPETLDEGDIEHFEILPDILQEYLLYVRYTAILIDPFSQPDENGHY
                     FDFSAVPFKQVYKNEQDVVQIPRMPSEDYYRTAMIQHIGKMLGIKTPMIDQFLTRYEA
                     SCQAYKDMHQDQQLSSQFNTNLFEGDKALVTKFLEINRTLS"
     gene            11299..12897
                     /gene="cntA"
                     /locus_tag="RPH49_002042"
     CDS             11299..12897
                     /gene="cntA"
                     /locus_tag="RPH49_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylopine-dependent metal ABC transporter
                     substrate-binding protein CntA"
                     /protein_id="HDY5125171.1"
                     /translation="MRKLTKMSAMLLASGLILTGCGGNKGLEEKKENKQLTYTTVKDI
                     GDMNPHVYGGSMSAESMIYEPLVRNTKDGIKPLLSKKWDVSEDGKTYTFHLRDDVKFH
                     DGTPFDADAVKKNIDAVQENKKLHSWLKISTLIDNVKVKDKYTVELNLKEAYQPALAE
                     LAMPRPYVFVSPKDFKNGTTKDGVKKFDGTGPFKLGEHKKDESADFNKNDQYWGEKSK
                     LNKVQAKVMPAGETAFLSMKKGETNFAFTDDRGTDSLDKDSLKQLKDTGDYQVKRSQP
                     MNTKMLVVNSGKKDNAVSDKTVRQAIGHMVNRDKIAKEILDGQEKPATQLFAKNVTDI
                     NFDMPTRKYDLKKAESLLDEAGWKKGKDSDVRQKDGKNLEMAMYYDKGSSSQKEQAEY
                     LQAEFKKMGIKLNINGETSDKIAERRTSGDYDLMFNQTWGLLYDPQSTIAAFKAKNGY
                     ESATSGIENKDKIYNSIDDAFKIQNGKERSDAYKNILKQIDDEGIFIPISHGSMTVVA
                     PKDLEKVSFTQSQYELPFNEMQYK"
     gene            12910..13845
                     /locus_tag="RPH49_002043"
     CDS             12910..13845
                     /locus_tag="RPH49_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125172.1"
                     /translation="MFKFILKRIALMFPLVIVVSFMTFLLTYITNENPAVTILHAQGT
                     PNVTPELIAETNEKYGFNDPLLIQYKNWLLEAMQFNFGTSYITGDPVAERIGPAFMNT
                     LKLTIISSVMVMITSIILGVVSALKRGKFTDRAIRSVAFFLTALPSYWIASILIIYVS
                     VKLNILPTSGLTGPESYILPVIVITIAYAGIYFRNVRRSMVEQLNEDYVLYLRASGVK
                     SITLMLHVLRNALQVAVSIFCMSIPMIMGGLVVIEYIFAWPGLGQLSLKAILEHDFPV
                     IQAYVLIVAVLFIIFNTLADIINALLNPRLREGAR"
     gene            13842..14711
                     /locus_tag="RPH49_002044"
     CDS             13842..14711
                     /locus_tag="RPH49_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125173.1"
                     /translation="MIILKRLLQDKGAVVALGIIVLYVFLGLAAPLVTFYDPNHIDTA
                     NKFAGMSFQHLLGTDHLGRDILTRLIYAIRPSLLYVFVALFVSVLIGSILGFLSGYFQ
                     GFVDALIMRACDVMLAFPSYVVTLALIALFGMGAENIIMAFILTRWAWFCRVIRTSVM
                     QYTASDHVRFAKTIGMNDMKIIHKHIMPLTLADIAIISSSSMCSMILQISGFSFLGLG
                     VKAPTAEWGMMLNEARKVMFTHPEMMFAPGIAIVIIVMAFNFLSDALQIAIDPRISSK
                     DKLRSVKKGVVQS"
     gene            14708..15523
                     /locus_tag="RPH49_002045"
     CDS             14708..15523
                     /locus_tag="RPH49_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125174.1"
                     /translation="MTLLTVKHLTITDTWTDQPLVSDVNFTLTKGETLGVIGESGSGK
                     SITCKSIIGLNPERLGVTGDITFDGKPMLSLSEAQLKKYRGKDIAMVMQQGSRAFDPS
                     TTVGKQMFETMKVHTSMSTQEIEKTLIEYMDYLSLKDPKRILKSYPYMLSGGMLQRLM
                     IALALALKPKLIIADEPTTALDTITQYDVLEAFIDIKKHFDCAMIFISHDLTVINKIA
                     DRVVVMKNGQLIEHGTRESVLHHPKHVYTKYLLSTKKKINDHFKHVMRGDVHD"
     gene            15516..16265
                     /locus_tag="RPH49_002046"
     CDS             15516..16265
                     /locus_tag="RPH49_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125175.1"
                     /translation="MIKIKDVEKSYQSAHVFKRRRTPIVKGVSFECPIGATIAIIGES
                     GSGKSTLSRMILGIEKPDKGCVTLNDHPMHKKKVRRHQIGAVFQDYTSSLHPFQTVRE
                     ILFEVMCQCDGQPKDVMEVQAITLLEEVGLSKAYMDKYPNMLSGGEAQRVAIARAICI
                     NPKYILFDEAISSLDMSIQTQILDLLIHLRETRQLSYIFITHDIQAATYLCDQLIIFK
                     NGKIEEQIPTSALHKSDNAYTRELIEKQLSF"
     gene            16277..17470
                     /locus_tag="RPH49_002047"
     CDS             16277..17470
                     /locus_tag="RPH49_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125176.1"
                     /translation="MKGAMAWPFLRLYILTLMFFSANAILNVFIPLRGHDLGATNTVI
                     GIVMGAYMLTAMVFRPWAGQIIARVGPIKVLRIILIINAIALIIYGFTGLEGYFVARV
                     MQGVCTAFFSMSLQLGIIDALPEEHRSEGVSLYSLFSTIPNLIGPLVAVGIWNANNIS
                     LFAIVIIFIALTTTFFGYRVTFAEQEPDTSDKIEKMPFNAVTVFAQFFKNKELLNSGI
                     IMIVASIVFGAVSTFVPLYTVSLGFANAGIFLTIQAIAVVAARFYLRKYIPSDGMWHP
                     KYMVSVLSLLVIASFVVAFGPQVGAIIFYGSAILIGMTQAMVYPTLTSYLSFVLPKVG
                     RNMLLGLFIACADLGISLGGALMGPISDLVGFKWMYLICGMLVIVIMIMSLLKKPTPR
                     PANSL"
     gene            complement(17877..18626)
                     /locus_tag="RPH49_002048"
     CDS             complement(17877..18626)
                     /locus_tag="RPH49_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125177.1"
                     /translation="MSNTNKHYIEEEYATEQSRFFKRDIGFIFLYIFLVNILPIIIVF
                     LTFGLVAIFTQQAPWDFSFPISMNISYLLAVILSLAIFRRMHEDAFIPMIRSQIVAST
                     KYKWHILISFTLSIVLFLLLNHFEIFALNVDSFTVFDIYPLIREYGSISLIAIFSLTI
                     ILNTLICQLIFRHILIQELSRLIPLKITIVLSVILETLYYYPYINTWWEFIPALILAS
                     SATYLYLKSNRNFMVSYFYQLAVILVLHIFM"
BASE COUNT         6545 a         2781 c         3518 g         5794 t
ORIGIN      
        1 cctacaagat ttacatataa aattctatca tgtctgctat atataaacga aatgatatta
       61 gaatccttca ttttcaactt gtttaaaatt acgtttaatg ccgttataag aatatacaac
      121 attatataat tttacttggg cgtcatggac acttgagaag ggcattctta catcgtccat
      181 atttttaact tcgtgtcgaa atgctttttc agctttttgt ctttctgcaa gcgacatact
      241 tagccattct tctttgctaa ataaatcttc gaatcgaaaa tcaaatgcgg ttcttttact
      301 ttctgctctt aatgctaaaa cacgctcatg atatgtcacg ttttattcct ccctctaatc
      361 attcaatcga atgataaatc acagtattaa ctttagtact aatataatgt ttttacaata
      421 aagaagtgac gatttttcaa catttttaaa aataaaaaat ataagcaacg attaattgta
      481 tatttcgaat ggcttgtaat gtaatttatc tatgaaaatg aagcgagtta ttatgaccgt
      541 tatatgaatt gtgatacgct ttttaaaagt aatatgtatt tatgatttac cctgaaaaaa
      601 taaaaagaat caaaggagtc gatcattatg acagtattaa cagataaagt agcagtagtt
      661 acaggtgcag gtagtggtat tggagaagca attgcaacat tactacatga agagggtgtg
      721 aaagtcatct tagccggtag aaataaagat aaactacaaa atgtggcgaa tcaattagct
      781 caagatagtg tgaaggtagt gccaacagat gtaacgaaaa aagaagaagt cgatgaattg
      841 ataaaaattg cacaacaaac attcggtggt ttggatattg ttatcaatag tgcgggacaa
      901 atgttatcgt ctaagattac tgattatcaa gtagatgagt gggatagtat gattgatgtg
      961 aatatcaaag gcactttata tacggcacag gctgcattac caactatgtt agaacaatca
     1021 agtggtcatc ttattaacat tgcatctatt tctggctttg aagtaacgaa aagcagtacg
     1081 atttatagtg cgacgaaagc agcagttcac actattactc aaggattaga aaaagagttg
     1141 gcaaagacag gtgttaaagt aacaagcatt tctccaggaa tggtagatac agcaataact
     1201 gccgcataca atccaacaga tcgtaaaaaa cttgaaccac aagatattgc agaagcagta
     1261 ttatatgcat taacacaacc aaagcacgtt aacgtgaatg aaattacagt gcgtcctgta
     1321 taaaaaggtg tttgaggtct gggatatagg catttaatgt aatagctatc ggttttgtta
     1381 atattagtaa ggcaataatg atataagggc atgatagaca attattcctt gtacaattct
     1441 cagtaattgg tgattttaac aatcaagtga gtgaaggcga ctatattagt gttatgattt
     1501 ataatctata atgttcataa ttacagaact ataaaaactt tttcatttcc taccatattc
     1561 taggagttgc tttaatgacc aaaaaacatg tttttataat tattggtgtt attttatgta
     1621 tatgtatagt tgctacagtc atttatttaa aagtgaaata tgacgaaaaa gaaaagcaaa
     1681 aatcaattta ttataaagaa caacaagagc gtattacact ctatctcaag cataacacta
     1741 aagaaccgaa cacgatcaaa tctgtgcatt tcacaagttt aaagacagga cctatgggcg
     1801 atgccgtaat tgaaggttac atcaatgaaa ataaagaaga taattttgtt gcatatgggt
     1861 ctccagaaca taattatcaa tttggtggaa gtttaatcaa aagtaaaaat ttaagcacat
     1921 tattaaaacc agcacatcaa accaaaacgc ctgatgatat aaaaaaagaa ctagattcta
     1981 aaaagaacga ccgctaaaac aatgcggtcg ttttaatttt gctttcaagt taatcatact
     2041 tacacataaa aatgaaaagt tgaattttta gtacaatttt cactgtattt atctgttaac
     2101 cacttcataa ccgcaatatt ccgatgatct taaatgaaca cttttggctg cttttccttg
     2161 acctagatta aaattataga ttttctttgt aagagtgtgt tttgtagtat cataaatatg
     2221 taaactgtat aaaatcccac cacattttag gagctggtga tagatgtcga aaaagaaaat
     2281 tttaatatta actagtatta tgttaatcat attaattagt gttgcaagta tctattttaa
     2341 aatgaaatat gacgaaaaag aaaaacaaaa atcaatatac tataaagaac aacaagcgcg
     2401 cattacactt tatctcaagc ataacactaa agaaccgaac acgattaaat ctgtgcattt
     2461 cacaaaattg gaaacaagtc ctatgggaag tgctgtgatt gaaggttaca taaatgaaaa
     2521 caaaaaagat gattttgttg cctatgcatc acctgaaaat aactttcaat ttgtaggtga
     2581 tttaattaaa agtgaaagat taagtgagtt actaaaacca gcgcatcaat taaaatcacc
     2641 agatggtata aaaaaagaac taaataaaaa gaagagtcac taaagttagg agttgcttta
     2701 atgtccaaaa aacatggttt tataattatt ggtgtcattt tatgtatatg tatagttgca
     2761 tccgtcattt atttaaaaat gaaatatgac gaaaaagaaa aacaaaaaga aatttattac
     2821 aaaggacaac aagagcgcat tacactttat ctcaagcata ataccaaaga acccaatacc
     2881 atcaaatctg tacatttcac aagtttaaaa agaggaccta tgggcgatgc agtaattgaa
     2941 ggttacatca atgaaaataa agaagctgat tttgttgcat atgggtcacc tgaagaaaac
     3001 tatcaattca ctggaggatt gacaggaagt aatgaagtct taggaaaatt aaagaacgct
     3061 gaaaatttaa aatctcctga aaaaattaaa gaagaaataa acaaaaagaa aaacactaaa
     3121 cagtgatttt cacgtaatat ttagcttgat ttgtacatgt ttaatatcgt ttgctatcga
     3181 aggtgtttcg caattaatat aaatcacttc atcatcacca atacttcccc agttttttac
     3241 agtacattaa cacaagcgaa ccccattaat gtaaatggaa taatagtttg gccattataa
     3301 gaacaatata tacctaataa caatggcgat ggcgtgattt attgacatta tcaaattttc
     3361 tcaaatgtgt gtgatttttt ataaaaaagg gtagagcaag gtataatatc ctttcaatct
     3421 gttttcatat tttatatatt ttttaaatat aagcgctaaa tgttttaact aaagcataga
     3481 ttgacaagat gttatacaga atttcaaatt ctatccaata ttgttcgaag tgtagtatca
     3541 ctggattggt attaaacaat gtaaaggaga gattgcaaat gccgtataat tacaagaaac
     3601 aaaatggaga gttaatgtct gtaatgagcc aaggtgaaaa gtttattcat caatcacccg
     3661 ttaatgatga acttagtgca ttgattaagt tattaatttc taaaattaac ggttgtcatt
     3721 attgtgttga tatccataaa aaagaattaa aggaattggg tgtaacacaa atgaaaattg
     3781 atgaagtctt gagttttaga catttagatt tatttactga tcaagaaaaa gtgacgcttg
     3841 aatttgcaga aatgttaaat tcaatcaaag actttaagaa gtttgaaatt attgaccggc
     3901 taaaatcatt ttatgatgaa gaacaaatta ttgatcttgt ctttgttgta aaccaaatta
     3961 acggttggaa cagactaaat attattagtg ataaactata attgttcata taaatacaga
     4021 gtttcatctc gagcgctata tcataacaaa tcatgccact atacaggtca aatcttgtat
     4081 agtggcattt taatttatcc ctttgaatac tgttatttaa cgaatatcgg tccgcctggt
     4141 ccaacaggga tacctaatag gaaccaaata atgacaaata ctgtccacac aatacttagt
     4201 gcgattgaat acggcattaa actagaaagt aaggctccga gtttcatgcg tttatcgtat
     4261 ttttgtgcat aagttaataa taaaggtaag tacggcatca tcggtgtaat tggattggta
     4321 attgaatctc ctacacggta aatgacttgt gtgaatgcgg gatgaaagcc gataaggatt
     4381 aacattggta cgaatatcgg tcctaaaata ccccatttag ccgatgcgct tccgattaac
     4441 atgttgacca ttgcactcag tacgataata cctagtatca atacaatacc gttttgatgt
     4501 tctaataatt tggcaccttt aacagcagcg ataattccta aattactcca ctttaaatac
     4561 gcaagtagct gtgctgcaaa aaacacaata acgataaatg ttcccattga tcctacagca
     4621 tcgccgaaca ttttacctaa gtcttttgta tttttaattt ctttgcttaa aatcccataa
     4681 actaatccag gtactaaaaa tacgacaaga ataattaatc cgacaccgtt aattaatggc
     4741 gcatcgtcta gtaagctgcc tgttttagca tttcttaaaa agctatgttc aggaatggct
     4801 gtaataatta ataaaataat tgtgactatg aaactgatat ttgcccattt taaagcatgt
     4861 gcttctttgt cagtaatatg tgaagatgtt tcttcatggt catcatgcat taaactgtca
     4921 tcatattttc ctaatctagg aataatgagc ttagttgtaa ctagcaatat cgtaggaagt
     4981 aatacaacga cactcgctgc gataaagtac cagttcatag caacgtttgt tttaatagaa
     5041 tctgaaacga tacgtgttgc cggttctgta aatgaataga ccaaagcatc ttgcatacca
     5101 acaactatat ttgctgcaaa tcctccaaca gcggaagcat atgccatcgt taaaccagca
     5161 atagggtgat agccaatttt aataaaaagc attgctgcaa gcggcggcaa gataattgtc
     5221 gcagcatcgc cggctgtact acctaaaata ccaattaata taatagtcgg taaaattaaa
     5281 aatcgtggtg cgcgattcac aacagaaatc attaacttgt cgaagtatcc tgttttctct
     5341 gcaacaccaa taccaatcat cactgctagt actaagccta atgctgggaa ctctgagaaa
     5401 tttttaatcg tatcattcat tatcatcgta aatccatcat ggctaattat atttttaata
     5461 taaatggttt gatgtgtacc tggatgctta acagatacat taaataatga gataacccac
     5521 gtcataatgg ctaagcctat acacattaaa aagaataaga cgctaggatc tggcaattta
     5581 tttccaattt tttcaacact attcaagaaa cgattgacga tagacccctt ttgttgatgt
     5641 tttgatgtca tcaatgattc ccccctttgt taaatattta aagtgtaaca aaaaatactc
     5701 tcaaaagtaa caattttcag aaaatgaaaa gactaatatt gttaaatatt ttgagttatt
     5761 caatagaaat tgtatagcag agagtagcta agactgcctg gagacttatc tattaggttt
     5821 atgaagcatt gaacagtgga aaataaggac tgtaagttta agatatgttg tataggagtg
     5881 actgaatgaa acgtttggaa aataaagttg cagtcgtaac aggagcaagt acaggtatcg
     5941 gacaagcttc tgcaatcgct ttagctcaag aaggtgcgta tgtattggcg gtagacatag
     6001 ctgaagcggt atcggagact gtcgataaaa ttaaaagtaa tggtgacaat gcgaaggcgt
     6061 ataatgtgga tatttcagat gaacaacaag tggtagactt tgtgtctgac ataaaggaac
     6121 agtttggaag aatcgatgtg ttgtttaata atgccggtgt ggatgatgcg tctggtagaa
     6181 ttcatgagta tccaatagat gtgtatgaca agattatgaa tgtagatatg cgtgggacat
     6241 ttttaatgac gaaaatgatg ttacctttaa tgatgaatca aggtggctct attgttaata
     6301 cgtcttcatt ttcaggacag gcagcagatt tgtatcgctc aggatataat gctgcgaaag
     6361 gcgcagtgat taattttaca aaatcaatcg caattgagta tggtcgtgat ggcattcgat
     6421 ccaatgcaat tgcaccaggt acaattgaaa ccccgttagt agataaactg acaggtacga
     6481 gtgaggatga tgcaggtaaa acatttagag aaaatcaaaa atggatgact ccgctgggac
     6541 gtttaggtaa accagaagaa gtaggcaagc tcgttgtctt tttagcatct gatgacagtt
     6601 catttattac tggtgaaaca attcgcattg acggtggtgt tatggcttac acatggcctg
     6661 gcgagatgtt gagtgatgat tcgtggaagc ggacattgga ataattgttt taaaatcgat
     6721 atccagtgga aaataatttg gcatgaagta ggcaatgtat gcatattgtc gcaatgacag
     6781 acatttaaat cggagattaa ttaatctttg aaaatcacat attgttcatt tgaagtgtat
     6841 tgcttaaagc ttgttttaac gtattgtagg tcgtgcatct aatttatcag aatctcgagt
     6901 tcaaactttt ggagtatctt taaaataagc tgtattttgt ctattctaat aaattaagga
     6961 gaattttatg ttaaaagaaa aagaaagttt tagattgcta tatcaagcta taagagagat
     7021 tgcagataaa attggagata atcagttaga aactaattcc gttagtttat tattattgga
     7081 ctttgatttt gaacatgaag tatttgatga attgtatctt gcgattttaa aatatttaaa
     7141 tacagtaagt atagagaaca taagtcatag tgaacttttg aatttaatag aaaatacgat
     7201 tccagaagat cgagagatta acacgtttgt aaaaaataaa ataataattg gctttgctaa
     7261 taattatttc cctgaattac aagtattagc aaacgaaata aaatctgata tggctagttc
     7321 attaaaacaa tgatattttt atttaaattt ttaaagcttt gtacgaaatt gtacaaagct
     7381 ttttttggtg cgtattgtat gggcaacaac ttgacgatga aaatccgtta caggattggt
     7441 aataggaaat gttagcgaaa gacaagggta tccattgtag attaacaaaa ggacgtttcc
     7501 acaagtgtgg gttattctca ctaaagcaat acgcagagac aacttacgta aaattttgaa
     7561 ctgacgagaa cgaaacttct actcaattat tgataaaaat tttcaaaaag acttgaatgt
     7621 gctgagaata cgatgtttat ggaaggatta tcaaaatata aatgagcatt catttacaac
     7681 ctttattgac aatgattctc aactaatata gtatataatc aaatcgtaat agttacgatt
     7741 tgttttctgc aacttttttg aagttttagt tgaggtgaaa acagtaaaag catctaagtg
     7801 aatgtagtta acggacaact gcattcgctt gtagagccac aagaagcaac tttaaataag
     7861 gtttacggtt gcatgttgat gcaacaaccg attactaagt catgctttcc actttgcggg
     7921 ttagcatgac ttacctaata gatgggaaac tattaggttc accttctaaa aaattacagt
     7981 tatagaggaa tacagttgct tgcttcgcac caactgcata agagcctgag acataaatca
     8041 atgttctatg ctctacaaag ttataatggc agtagttgac tgaacgaaaa tgcgcttgta
     8101 acaagctttt ttcaattcta gtcaaccttg ccggggtggg acgacgaaat aaattttacg
     8161 aaaatatcat ttctgtccca ctccctaaaa atacatctaa aggagtgtcg tatgaatcgg
     8221 caggttatag aattttctaa gtataatcct tcggggaata tgacgatact tgttcattca
     8281 aaacatgatg ctagtgaata tgcatctatc gccaatcagt tgatggccgc aacacatgta
     8341 tgttgtgaac aggtaggctt tatagaatca acacaaaatg atgatggcaa tgattttcac
     8401 ttagttatga gcggtaatga attttgcggt aatgcgacga tgtcatatat acatcatttg
     8461 caggaaagtc atttgcttaa agaccaacag tttaaggtga aggtatctgg ctgttcggat
     8521 ttagtgcaat gcgcaattca tgattgccaa tactatgaag ttcaaatgcc acaagcccat
     8581 cgtgttgtac caacaacaat taatatgggt aatcattcat ggaaagcaat agaaattatt
     8641 tatgaaacat atgtacatta tgtgattcca gttaaacaag taacaacaga aattcaacat
     8701 ttggttgaat cgtatgttcg taagcaacaa tggaatcaca aatataaaac agtaggtatg
     8761 atgctttttg atgaacaacg tcaattttta cagccattaa tctatatacc agaaatccaa
     8821 agtttaattt gggaaaatag ctgtggttct ggtacagcat caattggggt ttttaataat
     8881 tatcaacgta atgacgcatg taaagatttt acagtacatc agccaggggg cagtatttta
     8941 gtgacatcaa agcgatgtca tcaattggga tatcaaactt caattaaagg acaggttaca
     9001 actgtagcta caggaaaagc atatatagaa taaggagcct acaatgaata actttaataa
     9061 tgaaatcaaa ttgatattac aacaatattt agaaaagttt gaagcgcatt acgagcgtgt
     9121 attacaagac gatcaatata tcgaagcatt agaaacattg atggatgact atagtgaatt
     9181 tattttaaat cctatttatg aacaacaatt taatgcttgg cgtgacgttg aagaaaaagc
     9241 acaattaata aaatcgctgc aatatattac agcgcagtgt gttaaacaag tggaagtcat
     9301 tagagcgaga cgtctattag acggacaggc gtctaccaca ggttactttg acaatataga
     9361 acattgtatt gatgaagagt ttggacaatg tagtatagct agcaatgaca aattattgtt
     9421 agttggttca ggtgcatatc caatgacgtt aattcaagta gcaaaagaaa caggtgcttc
     9481 agttatcggt attgatattg atccacaagc cgttgaccta ggacgtagaa tcgttaacgt
     9541 cttagcacca aatgaagata taacaattac ggatcaaaag gtatctgaac ttaaagatat
     9601 caaagatgtg acgcatatca tattcagctc gacaattcct ttaaagtaca gcattttaga
     9661 agaattatat gatttaacaa atgaaaatgt cgtagttgca atgcgctttg gtgatggcat
     9721 caaagcaata tttaattatc cgtcacaaga aacagcggaa gataagtggc aatgtgtgaa
     9781 taaacatatg agaccacagc aaatttttga tatagcactt tataaaaaag cagctataaa
     9841 ggtaggtatt acggatgtct aaattattaa tgataggcac tggtccggtc gcaatccaat
     9901 tagcgaatat ttgctattta aaatcagatt atgagattga tatggttgga cgtgcctcaa
     9961 catcagaaaa atcaaaacgc ttatatcaag cgtataaaaa agagaaacaa tttgaagtca
    10021 aaatacaaaa cgaggcgcat caacatctgg aaggtaattt tgaaattaat cgtttgtata
    10081 aagatgttaa aaacgttaag ggtgaatacg aaacggttgt catggcatgc acagcagatg
    10141 cttattatga cacactacag caattgtcgt tagaaacttt gcaaagtgtc aaacatgtca
    10201 ttttaatatc accgacattt ggttcgcaaa tgattgtcga acaatttatg tctaaattta
    10261 ataaagatat cgaagtgatt tcattctcaa cttatcttgg cgatacacgt attgttgata
    10321 aagaagcgcc taatcatgtg ttgacaacag gtgtaaaaaa gaaattgtac atgggatcga
    10381 cacattcaaa ctcaacaatg tgtcaacgaa tctctgcttt agctgagcaa ttgaagattc
    10441 aattagaagt cgttgaatcg ccactgcatg ctgaaacacg taacagttcg ctttatgtgc
    10501 acccaccact atttatgaat gacttttcat tgaaagccat tttcgaagga acggatgtac
    10561 cggtttatgt gtataagtta tttcctgaag gaccgataac gatgacacta atccgtgaaa
    10621 tgcgtttaat gtggaaggaa atgatggcta ttttacaagc atttagagtg ccgtcagtca
    10681 acctgattca atttatggtg aaggaaaatt atccagtacg tcctgaaact ttggatgaag
    10741 gtgatattga gcatttcgaa atcttgccag atatcttaca agaatatctg ctttatgtaa
    10801 gatataccgc aatcctcatt gatccatttt cacagccaga cgaaaacgga cattactttg
    10861 atttttcagc tgtaccattt aagcaagtct ataaaaatga acaggatgtt gttcaaattc
    10921 caagaatgcc aagtgaagat tattacagaa cggcgatgat tcagcatatt gggaaaatgc
    10981 taggtatcaa aacgccaatg attgatcagt tcctaactcg ctatgaagca agttgccagg
    11041 cgtacaagga tatgcatcaa gatcaacaac tatcttctca atttaataca aatctttttg
    11101 aaggagataa ggcactcgtc acaaaatttt tggaaatcaa tagaacgctt tcataataag
    11161 ggtttgaagt tttataatag aaaaaaatta ttgaattatg tttgacattt acataaaaat
    11221 aagcaaataa ttgagaaaaa taatcattac gatttgatta agtaatgcaa cttatcaatt
    11281 tagaaagagg aaaagcaaat gagaaaacta actaaaatga gtgcaatgtt acttgcatca
    11341 gggctaattt taactggttg tggcggtaat aaaggtttag aggagaaaaa agaaaacaag
    11401 caattaacgt atacgacagt taaagatatc ggtgatatga atccgcatgt ttacggtgga
    11461 tcgatgtctg ctgaaagtat gatatacgag ccgcttgtac gtaacacgaa agatgggatt
    11521 aagcctttac tatctaaaaa atgggatgtg tctgaagatg ggaagacata cacgttccat
    11581 ttgagagatg acgttaaatt ccatgatggt acgccatttg atgctgacgc agttaagaaa
    11641 aatattgacg cagttcaaga aaacaaaaaa ttgcattctt ggttaaagat ttcaacatta
    11701 attgacaatg ttaaagttaa agataagtac acggttgaat tgaatttgaa agaagcatat
    11761 caacctgcat tggctgaatt agcgatgcct cgtccatatg tatttgtgtc tccaaaagac
    11821 tttaaaaacg gcacaacaaa agatggcgtt aaaaagttcg atggtactgg tccatttaaa
    11881 ttaggtgaac acaaaaaaga tgagtctgca gactttaaca aaaatgatca atactggggc
    11941 gaaaagtcta aacttaacaa agtacaagca aaagtaatgc ctgctggtga aacagcattc
    12001 ctatcaatga aaaaaggtga aacgaacttt gccttcacag atgatagagg tacagatagc
    12061 ttagacaaag actctttaaa acaattgaaa gatacaggtg actatcaagt taagcgtagt
    12121 caacctatga atacgaaaat gttagttgtc aattctggta aaaaagataa cgcagtcagt
    12181 gacaaaacag tcagacaagc gattggtcat atggtaaaca gagataaaat tgccaaagaa
    12241 attttagatg gtcaagaaaa accagcaact caattatttg cgaaaaatgt aacagatatt
    12301 aatttcgata tgccaacacg taagtatgac cttaaaaaag cagaatcatt attagatgaa
    12361 gctggttgga agaaaggtaa agacagcgat gttcgtcaaa aagatggtaa aaaccttgaa
    12421 atggcaatgt actatgacaa aggttcttca agtcaaaaag aacaagcaga atacttacaa
    12481 gcagaattta agaaaatggg tattaagtta aacatcaatg gcgaaacatc agataaaatt
    12541 gctgaacgtc gtacttctgg tgattatgac ttaatgttca accaaacttg gggattattg
    12601 tacgatccac aaagtactat tgcagcattt aaagcgaaaa atggttatga aagtgcaaca
    12661 tcaggcattg agaacaaaga taaaatatac aacagcattg atgacgcatt taaaatccaa
    12721 aacggtaaag agcgttcaga cgcttataaa aacattttga aacaaattga tgatgaaggt
    12781 atctttatcc ctatttcaca cggtagtatg acagttgttg cgccgaaaga tttagaaaaa
    12841 gtatcattca cacaatcaca gtatgaatta ccattcaatg aaatgcagta taaataaagg
    12901 agcaattaga tgttcaaatt tatcttaaaa cgtattgcgc tcatgtttcc attagtgatt
    12961 gtagtaagtt ttatgacatt tctattgacg tatattacaa atgaaaatcc agctgtgaca
    13021 attttacatg cacaagggac gccaaatgta acaccagagt tgattgcaga aacgaatgag
    13081 aagtacggtt tcaatgatcc attattaatt caatataaaa attggttact tgaagcgatg
    13141 caatttaatt ttggtacaag ctacattaca ggtgatcctg ttgctgaacg cattggtcca
    13201 gcatttatga atacattgaa attaacaata atttcaagtg ttatggtgat gattacatca
    13261 attattttag gtgtagttag tgcattaaaa agaggaaagt tcactgatcg tgcgatacgt
    13321 tcagtggctt tctttctaac tgcattacca tcatattgga tagcttcaat acttattatt
    13381 tacgtttcag tgaagttaaa catattgccg acttctggat taacaggtcc agaaagttac
    13441 atattgccag tgatcgttat tacgattgcc tatgctggta tttactttag aaatgttaga
    13501 cgctcgatgg tggaacaatt aaatgaagat tatgtacttt atttaagagc aagcggtgtg
    13561 aaatctatca cattaatgtt gcatgtgttg cgtaatgctt tacaagttgc ggtatcaatc
    13621 ttttgtatgt ctataccaat gataatgggt ggactagttg ttatcgagta tatctttgca
    13681 tggcctggac taggtcaatt aagtttaaaa gcaatacttg aacatgattt tccagttatt
    13741 caagcatatg tattaattgt agcggtatta tttattatat ttaatacatt agcagatatc
    13801 attaatgcgc tattaaatcc aagattaagg gagggcgcac gatgataatt ttaaaacgat
    13861 tattacaaga taaaggtgca gtggttgctt taggcattat tgtattatat gtctttttag
    13921 gattagcagc accacttgtg acattttatg atcctaacca tatcgataca gcaaacaaat
    13981 ttgctggcat gagttttcaa catctactag gtactgacca tttaggtaga gatattttaa
    14041 ctaggttaat ttatgcgatt agaccaagtt tgttatatgt ctttgttgcg ctatttgttt
    14101 ctgtacttat tggatctatt ttaggattct tatcaggata tttccaaggg tttgttgacg
    14161 ccttaatcat gcgtgcgtgt gatgttatgt tggcattccc aagttatgtt gtaacgttag
    14221 cattaattgc attgtttggt atgggtgccg aaaatattat catggcattt attttgacgc
    14281 gttgggcatg gttctgtcgt gttatacgta caagtgttat gcagtacact gcttctgacc
    14341 atgtaagatt tgctaaaaca atcggtatga atgatatgaa aattattcac aaacatatta
    14401 tgccgttaac attagcagat attgctatta tctctagtag ctcgatgtgt tcaatgatct
    14461 tgcaaatatc tggcttttca tttttaggat taggtgtcaa agcgcctact gcagagtggg
    14521 gcatgatgct taacgaagct agaaaagtga tgtttacaca tcctgaaatg atgtttgcgc
    14581 caggtattgc catagtgatt atagtgatgg catttaactt cttatccgat gctttacaaa
    14641 ttgccattga tccccgcatc tcttctaaag ataaacttcg ttctgtgaaa aaaggagtgg
    14701 tgcaatcatg acattgttaa cagttaagca tttgacgatt acagatacct ggacagatca
    14761 accactcgtg agtgatgtga attttacatt aactaagggt gaaactttag gcgttattgg
    14821 agaaagtggt agtggtaaat caatcacttg taaatcgatt attggtttga atcccgaacg
    14881 actcggggtg acaggtgata taacctttga tggtaagcca atgttgtcgt tatccgaagc
    14941 acaattgaaa aaataccgtg gtaaagatat tgcgatggtc atgcaacaag gtagtcgtgc
    15001 atttgatcca tcgacaacag taggtaaaca aatgtttgag actatgaaag tacatacgtc
    15061 aatgtctaca caagaaattg aaaagacatt gattgaatat atggattatt taagtttgaa
    15121 agatcctaaa cgtatattaa aatcataccc ttacatgtta tcaggaggaa tgttacagcg
    15181 attgatgatt gctttagcgt tagctttgaa accaaagtta atcattgctg atgagccgac
    15241 aacggcttta gatacaatta cacaatatga tgtactggaa gcatttatag atattaaaaa
    15301 acactttgac tgtgcgatga ttttcatttc acatgattta acggttatta acaagattgc
    15361 agatcgtgtt gttgtgatga aaaatggtca actgattgag catggtacgc gtgaatcagt
    15421 cttgcatcat ccaaaacatg tttacacgaa gtatttattg tcaaccaaga agaagattaa
    15481 tgatcatttt aaacatgtga tgaggggtga tgtacatgat taaaattaaa gatgttgaaa
    15541 agtcatatca aagcgcacat gtttttaagc gtcgtcgaac acctatcgtg aaaggtgtgt
    15601 catttgagtg tccaatcggt gcgacgattg cgattatcgg agaaagtggt agcggtaaat
    15661 cgacgttgag tcgtatgata ttaggtattg agaaaccgga taaaggttgt gtaaccttaa
    15721 atgatcatcc gatgcataag aagaaagtga gacgtcatca aattggtgca gtgtttcaag
    15781 attatacgtc atcattacac ccatttcaga ctgttagaga aatcttattt gaagtgatgt
    15841 gtcaatgtga tggacaacct aaagatgtta tggaagtcca agcaattaca ttgttggaag
    15901 aagtcggtct atctaaggca tacatggata aatatcctaa tatgttatca ggtggagagg
    15961 cgcaacgtgt tgcgattgcg cgtgcaatat gtattaaccc taaatatatt ttgtttgatg
    16021 aagccattag ttcactcgac atgtcaattc aaacacaaat attagattta ttgattcatt
    16081 tacgtgaaac gcgtcagttg agttatattt ttatcacaca tgatattcaa gctgccacgt
    16141 atttatgtga tcaattaatt atttttaaaa acggaaaaat agaagaacaa attccgacaa
    16201 gcgcattgca taaaagtgac aatgcttata caagagaatt aatagaaaaa caactatcat
    16261 tctaaggagt gagataatga aaggtgcaat ggcttggccc tttttgagat tatatatatt
    16321 aacattgatg ttctttagtg ccaatgcaat cttaaacgtg tttatacctt tgcgaggtca
    16381 tgatttaggc gcaacgaata cggttatcgg tatcgttatg ggggcataca tgttaacagc
    16441 aatggtattt cgaccatggg caggacaaat tattgctcgt gtcggtccca ttaaagtatt
    16501 aagaattatt ttgattatca atgccatagc tttaattatt tatggtttta ctggcttaga
    16561 aggttatttc gtagcacgtg ttatgcaagg tgtgtgtacg gcattctttt ctatgtcttt
    16621 acagctaggt attattgatg cattaccaga ggaacatcgt tctgaaggtg tatcattgta
    16681 ctcgctattt tcaacgattc caaacttaat cggcccatta gttgccgtag gtatttggaa
    16741 tgcaaataat atttcactat ttgcaattgt cattatcttt atcgcattaa caacaacatt
    16801 ctttggctat cgcgtgacct ttgctgaaca agaacccgat acgtcagata agattgaaaa
    16861 aatgccattt aacgctgtaa ctgtttttgc gcaatttttc aaaaataaag agttgttgaa
    16921 cagtggtatt atcatgattg ttgcatcgat tgtatttggt gcagttagta catttgtacc
    16981 gttatacaca gtgagtttag gattcgcgaa tgcgggaatc tttttgacaa tacaggccat
    17041 cgcagttgtt gcggcaagat tttacttaag gaaatacatt ccgtcagatg gtatgtggca
    17101 tcctaaatat atggtatctg tactatcatt attagtgatc gcgtcatttg tagtggcatt
    17161 tggtccgcaa gtaggtgcaa ttattttcta tggtagtgcg atattaatag gaatgacgca
    17221 agcaatggtg tacccaacat taacatcata cttaagtttc gtcttaccaa aagtaggtcg
    17281 taatatgttg ttaggtttat ttattgcctg tgcagactta ggtatatcgt taggtggcgc
    17341 attgatggga cctatttccg atttagtagg atttaaatgg atgtatctaa tttgtggtat
    17401 gttagtcatt gtaataatga ttatgagttt attgaaaaaa ccaacaccac gcccagcaaa
    17461 tagtctttaa tgaagtgaat taaagcatat taagttaatg aatatttaaa ttttaaaagg
    17521 tatattgagc atggcgattc atgggagtgg gacagaaatg atattttcga aaaatttatt
    17581 tcgtcgtccc accccaactt gcattgtctg tggaaattgg gaatccaatt tctctttgtt
    17641 ggggcccctg actagaattg aaaaaagctt gttacaagcg cattttcgtt cagtcaacta
    17701 ctgccaatat aactttgtag agcattgaac attgatttat gtctcaggct ctctatatgg
    17761 ctcgttttta gaacgacagt atatctaaat aaagcacgct tagaagtgag ttgcgatact
    17821 gacttttaag tgtgcttttt gatgtgtatg gataatggat aatgctctga aaaattttac
    17881 atgaaaatat gcaaaacgag tataactgct aattgataga aatagctcac cataaaatta
    17941 cggtttgatt ttaaatataa gtaagtcgca ctactagcta gtatcaatgc tggaatgaat
    18001 tcccaccatg tattaatgta tggataatag tacagtgttt caaggataac ggataatact
    18061 attgtaatct ttaaaggtat taatctgctt aattcttgaa ttaaaatatg acggaaaata
    18121 agttgacaaa tcaaagtatt taatataatg gttaacgaaa atatagctat taaactgatg
    18181 gaaccatatt ctctaatgag cgggtaaatg tcaaagacag taaaggaatc tacatttagt
    18241 gcgaaaattt cgaaatgatt taaaagtaaa aagagtacga tacttaatgt aaatgatata
    18301 agaatatgcc atttatattt ggtgctggca acgatttgcg aacgtatcat tggaataaac
    18361 gcatcttcat gcatccgacg aaaaatagct aatgaaagaa taactgcgag taaatagcta
    18421 atgttcattg aaataggaaa agagaaatcc cacggagctt gttgagtgaa tatagctact
    18481 aacccaaaag ttaaaaaaac gataatgatc ggcaagatgt taaccaaaaa tatgtaaagg
    18541 aaaataaatc caatatcacg tttgaaaaaa cgcgattgtt cggtagcgta ttcttcttct
    18601 atgtaatgtt tatttgtatt tgacatagta tacctctt
//
LOCUS       DAPSKH010000054        18277 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPSKH010000054 DAPSKH010000000
VERSION     DAPSKH010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 18277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18277
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.054"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            94..636
                     /locus_tag="RPH49_002049"
     CDS             94..636
                     /locus_tag="RPH49_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF697 domain-containing protein"
                     /protein_id="HDY5125178.1"
                     /translation="MGFKNNLTSNLTNKIGNSVFKIENVDGKGAMPTTIQELRERRER
                     AEAIVKRKSLMSSTMSVVPIPGLDFGVDLKLMKDIIEDVNKIYGLDHKQVNSLGDDVK
                     ERIMSAAAIQGSQFIGKRISSAFLKIVIRDVAKRTAAKQTKWFPVVGQAVSASISYYF
                     MNKIGKDHIQKCENVIKNVM"
     gene            790..1056
                     /locus_tag="RPH49_002050"
     CDS             790..1056
                     /locus_tag="RPH49_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDY5125179.1"
                     /translation="MEQNSYVIIDETGIHARPATMLVQTASKFDSDIQLEYNGKKVNL
                     KSIMGVMSLGVGKDAEITIYADGSDESDAIQAISDVLSKEGLTK"
     gene            1059..2777
                     /gene="ptsP"
                     /locus_tag="RPH49_002051"
     CDS             1059..2777
                     /gene="ptsP"
                     /locus_tag="RPH49_002051"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDY5125180.1"
                     /translation="MSKLIKGIAASDGVAIAKAYLLVEPDLTFDKNEKVTDVEGEVAK
                     FNNAIEASKVELTKIRNNAEVQLGADKAAIFDAHLLVLDDPELIQPIQDKIKNENANA
                     ASALTDVTTQFVTIFESMDNEYMKERAADIRDVSKRVLSHILGVELPNPSMIDESVVI
                     VGNDLTPSDTAQLNKEFVQGFATNIGGRTSHSAIMSRSLEIPAIVGTKSITQEVKQGD
                     MIIVDGLNGDVIVNPTEDELIAYQDKRERYFADKKELQKLRDADTVTVDGVHAELAAN
                     IGTPNDLPGVIENGAQGIGLYRTEFLYMGRDQMPTEEEQFEAYKEVLEAMDGKRVVVR
                     TLDIGGDKELSYLNLPEEMNPFLGYRAIRLCLAQQDIFRPQLRALLRASVYGKLNIMF
                     PMVATINEFREAKAILLEEKENLKNEGHDISDDIELGIMVEIPATAALADVFAKEVDF
                     FSIGTNDLIQYTLAADRMSERVSYLYQPYNPSILRLVKQVIEASHKEGKWTGMCGEMA
                     GDETAIPLLLGLGLDEFSMSATSILKARRQINGLSKNEMTELANRAVDCATQEEVIEL
                     VNNYVK"
     gene            complement(3014..3247)
                     /gene="nrdH"
                     /locus_tag="RPH49_002052"
     CDS             complement(3014..3247)
                     /gene="nrdH"
                     /locus_tag="RPH49_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDY5125181.1"
                     /translation="MSEIIVYTQNDCPPCTFVKNYLNEHQIDFEERNINNQQYRNEMI
                     DFDAFSTPFILLNGNPMYHVDLDEINKVLNIQD"
     gene            3445..4806
                     /locus_tag="RPH49_002053"
     CDS             3445..4806
                     /locus_tag="RPH49_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDY5125182.1"
                     /translation="MDTVEISRFLTAMTLAVHIIFATIGVGMPLMFAIAEFLGIRKND
                     LQYIAMAKRWAKAYTITVAVGVVTGTIIGLQLSLIWPTFMEMGGHVIALPLFMETFAF
                     FFEAIFLSIYLYTWDRFKNKWTHFLISIPVIIGGSFSAFFITSVNSFMNTPAGFELKN
                     GKMVNVQPIEAMFNPSFIVRSFHVITTAGMTMAFVIASIAAFKLLRNRQPKDTVYHKK
                     ALKMSMIVGFFSTLLSMLAGDLSAKFLHKFQPEKLAAYEWHFDTSSHAKLLLFGVLDE
                     KTQQVKGAIELPGLLSFLADNSVKTKVQGLNDFPKSLHPPMIVHYFFDLMVTMGILCF
                     VISGVYVLTLMFKKLRKFSTHKWMLYGILLTGPASMLAIEFGWFLTEMGRQPWIVRGY
                     MRVAEAATQAGGITFVTILFGILYIILMYTCAYVLIRMFKNKPAYEDVNRLAKKQGGE
                     IEK"
     gene            4803..5822
                     /locus_tag="RPH49_002054"
     CDS             4803..5822
                     /locus_tag="RPH49_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDY5125183.1"
                     /translation="MIYAFIGITVLWLFLFCYIIIASIDFGAGFFALHSKLTGDEKKI
                     NHLISRYLNPVWEVTNVFFVFFFVGFVGFFPESIKYLGTVLLIPGSIALIMISLRNSF
                     YAFENYGQDTKLAWMIMYGVSGLLIPASLSTALTITEGGYINVRNNVIDLDWVQLLLS
                     PFAWSVVFLAIISVLYISSGFLTYYAKKANDEPAYNLTRQWHIFLGPPMIIICLFVFL
                     SLRIQNSEHFYSAVFDYWWMFAISFLFFALASLLTFFKKKHGLAFVFVILQMMFAFFG
                     YGISKLPYLLYPFVKITDAYVNPEMGWTLVIVFILGLLLLLPSLILLLRLFVFDKEYV
                     EGKKS"
     gene            5955..6617
                     /locus_tag="RPH49_002055"
     CDS             5955..6617
                     /locus_tag="RPH49_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDY5125184.1"
                     /translation="MGKEYVVIGLGRFGGSIVRELNALDMDVMAIDHDENRVNEYSDI
                     ATHAVVADTTDEAVMKSLGIRNFDHVIVAIGENIQSSTLTTLILKELGVKKVTAKAQN
                     DYHAKILNKIGADTVVHPERDMGRRIAHNVASASVLDYLELADEHSIVELKATEKMAG
                     KSIIDLDIRAQYGINIIAIKRGKEFIISPNPNINLEIGDILIMIGHDNDLNRFEKNIA
                     TR"
     gene            complement(7025..8722)
                     /locus_tag="RPH49_002056"
     CDS             complement(7025..8722)
                     /locus_tag="RPH49_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDY5125185.1"
                     /translation="MKQLHPNEVGVYALGGLGEIGKNTYAVEYKDEIVIIDAGIKFPD
                     DNLLGIDYVIPDYTYLVQNQDKIVGLFITHGHEDHIGGVPFLLKQLNIPIYGGPLALG
                     LIRNKLEEHHLLRTAKLNEINEDSVIKSKHFTISFYLTTHSIPETYGVIVDTPEGKVV
                     HTGDFKFDFTPVGKPANIAKMAQLGEEGVLCLLSDSTNSLVPDFTLSEREVGQNVDKI
                     FRNCKGRIIFATFASNIYRVQQAVEAAIKNNRKIVTFGRSMENNIKIGMELGYIKAPP
                     ETFIEPNKINTVPKHELLILCTGSQGEPMAALSRIANGTHKQIKIIPEDTVVFSSSPI
                     PGNTKSINRTINSLYKAGADVIHSKISNIHTSGHGSQGDQQLMLRLIKPKYFLPIHGE
                     YRMLKAHGETGVECGVEEDNVFIFDIGDVLALTHDSARKAGRIPSGNVLVDGSGIGDI
                     GNVVIRDRKLLSEEGLVIVVVSIDFNTNKLLSGPDIISRGFVYMRESGQLIYDAQRKI
                     KTDVISKLNQNKDIQWHQIKSSIIETLQPYLFEKTARKPMILPVIMKVNEQKESNNK"
     gene            complement(8722..8940)
                     /locus_tag="RPH49_002057"
     CDS             complement(8722..8940)
                     /locus_tag="RPH49_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDY5125186.1"
                     /translation="MAVFKVFYQHNRDEVIVRENTQSLYVEAQTEEQVRRYLKDRNFN
                     IEFITKLEGAHLDYEKENSEHFNVEIAK"
     gene            complement(8969..9091)
                     /locus_tag="RPH49_002058"
     CDS             complement(8969..9091)
                     /locus_tag="RPH49_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125187.1"
                     /translation="MNDMMNLVINQIVIKLNYRDDWNEFIDIYSNTILLGLTIN"
     gene            complement(9422..9973)
                     /locus_tag="RPH49_002059"
     CDS             complement(9422..9973)
                     /locus_tag="RPH49_002059"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDY5125188.1"
                     /translation="MLTMKDIIRDGHPTLRQKAAELELPLTKEEKETLIAMREFLVNS
                     QDEEIAKRYGLRSGVGLAAPQINISKRMIAVLIPDDGSGKSYDYMLVNPKIVSHSVQE
                     AYLPTGEGCLSVDDNVAGLVHRHNRITIKAKDIEGNDIQLRLKGYPAIVFQHEIDHLN
                     GVMFYDHIDKDHPLQPHTDAVEV"
     gene            10338..10964
                     /locus_tag="RPH49_002060"
     CDS             10338..10964
                     /locus_tag="RPH49_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkyA family protein"
                     /protein_id="HDY5125189.1"
                     /translation="MKFGKTIAVVLASSVLLAGCTTDKKEIKAYLKQVDKIKDDEEPI
                     KTVGKKIAELDEKKKKLTEDVNSKDTTVRGKAVKDLIKNADDRLKEFEKEEDAIKKSE
                     QDFKKAKSHVDNIDNDVKRKEVKQLDDVLKEKYKLHSDYAKAYKKAVNSEKTLFKYLN
                     QNDATQQGVNEKSKAIEENYKKLKEVSDKYTKVLNKVGKEKQDVDQFK"
     gene            11135..12247
                     /gene="pdhA"
                     /locus_tag="RPH49_002061"
     CDS             11135..12247
                     /gene="pdhA"
                     /locus_tag="RPH49_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002467471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDY5125190.1"
                     /translation="MAPKLQAQFDAVKVLNDTQSKFEMVQILDENGNVVNEDLVPDLT
                     DEQLVELMERMVWTRILDQRSISLNRQGRLGFYAPTAGQEASQLASQYALEKEDYILP
                     GYRDVPQIIWHGLPLTEAFLFSRGHFKGNQFPEGVNALSPQIIIGAQYIQAAGVAFAL
                     KKRGKNAVAITYTGDGGSSQGDFYEGINFAAAYKAPAIFVIQNNNYAISTPRSKQTAA
                     ETLAQKAIAVGIPGIQVDGMDALAVYQATKEARDRAVAGEGPTLIETMTYRYGPHTMA
                     GDDPTRYRTSDEDAEWEKKDPLVRFRKFLENKGLWNEDKENEVIERAKADIKAAIKEA
                     DNTEKQTVTSLMEIMYEDMPQNLAEQYEIYKEKESK"
     gene            12251..13228
                     /locus_tag="RPH49_002062"
     CDS             12251..13228
                     /locus_tag="RPH49_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017637695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDY5125191.1"
                     /translation="MAQMTMVQAINDALKTELKNDQDVLIFGEDVGVNGGVFRVTEGL
                     QKEFGEDRVFDTPLAESGIGGLAMGLAVEGFRPVMEVQFLGFVFEVFDAIAGQIARTR
                     FRSGGTKTAPVTIRSPFGGGVHTPELHADNLEGILAQSPGLKVVIPSGPYDAKGLLIS
                     SIRSNDPVVYLEHMKLYRSFREEVPEEEYTIDIGKANVKKEGNDISIITYGAMVQESM
                     KAAEELEKDGYSVEVIDLRTVQPIDVDTIVASVEKTGRAVVVQEAQRQAGVGAAVVAE
                     LSERAILSLEAPIGRVAAADTIYPFTQAENVWLPNKNDIIEKAKETLEF"
     gene            13319..14611
                     /locus_tag="RPH49_002063"
     CDS             13319..14611
                     /locus_tag="RPH49_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="HDY5125192.1"
                     /translation="MAFEFRLPDIGEGIHEGEIVKWFVKAGDTIEEDDVLAEVQNDKS
                     VVEIPSPVSGTVEEVMVEEGTVAVVGDVIVKIDAPDAEDMQFKGHDDDSSSKEEPAKE
                     EAPAEQAPVATQTEEVDENRTVKAMPSVRKYAREKGVNIKAVSGSGKNGRITKEDVDA
                     YLNGGAPTASNESAASTTSEEVAETPAAPAAVSLEGDFPETTEKIPAMRRAIAKAMVN
                     SKHTAPHVTLMDEIDVQALWDHRKKFKEIAAEQGTKLTFLPYVVKALVSALKKYPALN
                     TSFNEEAGEIVHKHYWNIGIAADTDRGLLVPVVKHADRKSIFQISDEINELAVKARDG
                     KLTADEMKGATCTISNIGSAGGQWFTPVINHPEVAILGIGRIAQKPIVKDGEIVAAPV
                     LALSLSFDHRQIDGATGQNAMNHIKRLLNNPELLLMEG"
     gene            14615..16021
                     /gene="lpdA"
                     /locus_tag="RPH49_002064"
     CDS             14615..16021
                     /gene="lpdA"
                     /locus_tag="RPH49_002064"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009383646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDY5125193.1"
                     /translation="MVVGDFPIETDTIVIGAGPGGYVAAIRAAQLGQKVTIVEKGNLG
                     GVCLNVGCIPSKALLHASHRFVEAQHSENLGVIAESVSLNFQKVQEFKSSVVNKLTGG
                     VEGLLKGNKVNIVKGEAYFVDNNSLRVMDEKSAQTYNFKNAIIATGSRPIEIPNFKFG
                     KRVIDSTGALNLQEVPGKLVVVGGGYIGSELGTAFANFGSEVTILEGAKDILGGFEKQ
                     MTQPVKKGMKEKGVEIVTEAMAKSAEETDNGVKVTYEAKGEEKTIEADYVLVTVGRRP
                     NTDELGLEELGVKFADRGLLEVDKQSRTSISNIYAIGDIVPGLPLAHKASYEAKVAAE
                     AIDGQAAEVDYIGMPAVCFTEPELATVGYSEAQAKEEGLAIKASKFPYAANGRALSLD
                     DTNGFVKLITLKEDDTLIGAQVVGTGASDIISELGLAIEAGMNAEDIALTIHAHPTLG
                     EMTMEAAEKAIGYPIHTM"
     gene            16189..16464
                     /locus_tag="RPH49_002065"
     CDS             16189..16464
                     /locus_tag="RPH49_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDY5125194.1"
                     /translation="MEYEYPIDLDWSNEEMISVINFFNHVEKYYESGVTAGDFMGAYK
                     RFKEIVPAKAEEKQIFNTFEKSSGYNSYKAVQDVKTHSEEQRVTAKK"
     gene            16608..17147
                     /locus_tag="RPH49_002066"
     CDS             16608..17147
                     /locus_tag="RPH49_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125195.1"
                     /translation="MNIGNKIKNLRRIKNLTQEELAERTDLSKGYISQIESEHASPSM
                     ETFLNIIEVLGTTPSEFFKDSENEKVLYKKEEQVIYDEYDEGYILNWLVSKSNEYDME
                     PLILTLKPGASYKNFNPSESDTFIYCMSGQITLNLGKEVYQAQEEDVLYFKARDNHRL
                     SNESNNETRILIVATASYL"
     gene            17160..18254
                     /locus_tag="RPH49_002067"
     CDS             17160..18254
                     /locus_tag="RPH49_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125196.1"
                     /translation="MEPLLSLKSVSKSYDDLNILDDIDIDIESGYFYTLLGPSGCGKT
                     TILKLIAGFEYPDSGEVIYQNKPIGNLPPNKRKVNTVFQDYALFPHLNVYDNIAFGLK
                     LKKLSKTEIDQKVTEALKLVKLSGYEKRNINEMSGGQKQRVAIARAIVNEPEILLLDE
                     SLSALDLKLRTEMQYELRELQSRLGITFIFVTHDQEEALALSDFLFVLKDGKIQQFGT
                     PTDIYDEPVNRFVADFIGESNIVEGRMVRDYVVNIYGQDFECVDMGIPENKKVEVVIR
                     PEDISLIKAEEGLFKATVDSMLFRGVHYEICCIDNKGYEWVIQTTKKAEVGSEVGLYF
                     DPEAIHIMVPGETEEEFDKRIESYEEVDNA"
BASE COUNT         6343 a         2656 c         3434 g         5844 t
ORIGIN      
        1 taaatattta aaagctgttt ttgtaaatat tagacattaa tttgataaaa aggggtatag
       61 tatcttattg agaaaaagaa gggtgatgat acaatgggat tcaaaaacaa tttaacatca
      121 aatttaacaa ataaaattgg taattcagtt tttaaaatag aaaatgttga cggaaaaggt
      181 gcaatgccaa cgacgattca agaattgaga gaaagacgcg aacgtgctga agcaattgta
      241 aagagaaagt ctttaatgtc atcaacaatg agcgttgttc caattccggg tttagatttt
      301 ggtgttgatt taaaattaat gaaagatatt atcgaagatg taaataaaat atacggatta
      361 gatcataagc aagttaatag ccttggggat gatgtaaaag aaagaattat gtctgcagca
      421 gcaattcaag gtagtcaatt tattggtaaa agaatttcaa gtgcattttt aaaaattgta
      481 attagagatg tagcaaaacg aactgcagct aaacaaacaa aatggtttcc tgttgtagga
      541 caagctgtgt ctgcatctat tagttactat tttatgaata aaattggaaa agatcacatt
      601 caaaaatgcg aaaatgttat taaaaatgtc atgtaggtgc tataatagtt ttgcaatttg
      661 caaattttac tgaaaccggt tttaaacgaa ttgaatttaa agcatggttt tggtaaagtt
      721 aaggtataaa actaagttag tattgtaata atattgaaga ttctaactat acgaaggaga
      781 aatgtaatta tggaacaaaa ttcatatgta atcatcgacg agactggtat tcacgctaga
      841 ccagcaacaa tgttagtaca aacagcttca aaattcgatt ctgatattca attagaatat
      901 aacggtaaaa aggttaactt aaaatcaatc atgggtgtta tgagccttgg tgttggtaaa
      961 gatgctgaaa ttacaattta tgctgacggt agtgatgaat ctgacgccat tcaagcaatc
     1021 agtgacgtct tatcaaaaga aggattgact aaataattat gtctaaatta attaaaggaa
     1081 ttgctgcatc tgatggtgtt gcaattgcta aagcttattt gttagttgag ccagacttaa
     1141 cattcgacaa aaatgaaaaa gtcactgatg ttgaaggaga agttgctaag ttcaataacg
     1201 ctatcgaagc ttctaaagtt gagttaacta aaattagaaa taatgcagag gttcaattgg
     1261 gtgctgataa agctgctatc tttgatgcac atttattagt tttagatgac cctgaattaa
     1321 ttcaaccaat tcaagataag attaaaaatg aaaacgctaa tgctgcttca gcattaacgg
     1381 atgtaacaac acaatttgtt acaatttttg aatctatgga taacgaatac atgaaagaac
     1441 gtgcggctga tattcgcgac gtttctaaac gtgtgttatc acatatttta ggtgtagaat
     1501 taccgaatcc gagtatgatt gatgaaagcg ttgttattgt agggaatgac ttaacgccat
     1561 ctgatactgc tcaattaaat aaagaattcg tacaaggttt tgctacaaac attggcggaa
     1621 gaacaagtca ctctgcaatt atgagtcgtt ctttagaaat tccagcaatt gttggtacaa
     1681 aatcaattac tcaagaagtt aaacaaggcg acatgattat cgtagatgga ttaaatggtg
     1741 atgtaatcgt taatccaact gaagatgagt taatcgctta tcaagataaa cgtgagcgtt
     1801 attttgctga caagaaagaa ttacaaaaac tacgtgatgc tgatactgtt acagttgatg
     1861 gtgttcacgc agagcttgct gcaaatattg gtacacctaa tgatttgcca ggtgttattg
     1921 aaaatggtgc acaaggtatc ggcttatata gaactgagtt tttatatatg ggtcgtgacc
     1981 aaatgcctac agaagaagaa caatttgaag cttataaaga agtattagaa gcaatggacg
     2041 gtaaacgtgt tgttgtacgt actttagata taggtggaga taaagaatta tcatacttaa
     2101 acttgcctga agaaatgaat ccattcttag gttaccgtgc gattcgttta tgccttgcgc
     2161 aacaagatat tttcagacca cagctacgtg cattattacg tgcatcagtt tatggtaagt
     2221 taaatatcat gttcccaatg gttgcaacaa ttaacgaatt tagagaagct aaagctatat
     2281 tattagaaga aaaagaaaac cttaaaaatg aaggtcatga catttcggat gatatagaat
     2341 taggaatcat ggtagagata cctgcaacag cagcattagc tgatgttttt gctaaagaag
     2401 tagatttctt cagtatcggt acaaatgatt taattcaata cacattagct gctgaccgta
     2461 tgtcagagcg tgtatcatat ctgtaccaac catataaccc ttcaatctta cgtttagtta
     2521 aacaagttat tgaagcgtca cataaagaag gtaaatggac aggtatgtgt ggtgaaatgg
     2581 ctggagatga aacagctatt ccattattgc ttggtttagg tttagatgag ttctctatga
     2641 gtgcaacgtc tattctgaaa gcaagaagac aaattaatgg tttaagtaaa aatgaaatga
     2701 ctgaacttgc taaccgtgca gtcgactgtg caacgcaaga agaagttatt gaattagtta
     2761 acaactacgt aaaataatta attctttcga aagacagaat tataaataaa cccgaagtat
     2821 tcattgtgag taattatgaa tacttcgggt tcttttttat gatttatgtt aatttcaatg
     2881 gaatgttgtt gctaactaat taaacaacta tgtgtcatta acaaaatgtt gttctttaat
     2941 taatgttagt taatttaaaa atcgatattt aatttatgat agctataaat gatgaagttg
     3001 atttagatga aaattaatct tggatattta atactttgtt gatttcatca agatcaacat
     3061 ggtacattgg attgccattc aacaaaataa acggagttga aaaagcatca aaatctatca
     3121 tttcgtttcg atattgttga ttgttgatat ttctctcttc aaaatcaatt tgatgctcat
     3181 ttagataatt ttttacaaat gtacaaggtg gacaatcatt ctgcgtataa acgattattt
     3241 ctgacatgta tcatgctcct tcgtgcttta ttctaatgta atatacacaa ttatacattg
     3301 aaattcaaat ttgtgaacac attgtggact gacataaatt atacacaatt tcatagcgca
     3361 taatgtttta aaaatacaca ttatagcaat tataattaag ttcattgtgt tgtcatcaaa
     3421 aaaagaaaaa ggtgatgttt ttaaatggat acagttgaaa tcagtcggtt tttgacagct
     3481 atgactttag cagttcatat catttttgca acgattggtg ttggtatgcc tttaatgttc
     3541 gcaattgcag aatttttagg tattcgcaaa aatgatcttc aatatatagc tatggccaaa
     3601 agatgggcta aagcttatac aattactgta gcagtgggag ttgttacagg tacaattata
     3661 ggacttcaat tatcattgat ttggcctaca tttatggaaa tgggtggaca cgttattgca
     3721 cttccattat ttatggaaac atttgcgttc ttctttgaag ctattttctt aagtatatat
     3781 ttatatactt gggatcgttt taaaaataaa tggacacatt tcttaattag tataccagta
     3841 attattggtg gctctttctc agcattcttc attacttcag tgaattcatt tatgaatacg
     3901 cctgcaggtt ttgagttgaa gaatggaaag atggtcaatg ttcaacctat agaagcgatg
     3961 tttaacccat cgtttatagt tcgatcattt cacgtaatta ctacagctgg tatgacgatg
     4021 gcatttgtta ttgcatcaat agcagctttt aaattattgc gtaatcgtca acctaaagat
     4081 actgtctacc ataagaaagc tttgaaaatg tctatgatag ttggattctt ttcaacatta
     4141 ctttctatgt tggcagggga tttatctgca aaatttttgc ataaattcca acctgaaaaa
     4201 ttagcagctt atgaatggca tttcgataca tcttcccatg ccaaattatt attatttggt
     4261 gtgttagatg aaaagactca gcaagttaaa ggtgcgattg aattacctgg actattgagt
     4321 ttcttagcag ataatagtgt caaaactaaa gtgcaagggt taaatgattt tccaaaaagt
     4381 ttacatccgc ctatgattgt ccattatttc tttgatttaa tggtaacgat gggaatttta
     4441 tgttttgtca tttcaggtgt ttatgtctta actttaatgt ttaaaaagct tagaaagttt
     4501 tctactcata aatggatgct ttacggaata ttattaaccg gaccagcttc aatgctagct
     4561 atagaatttg gatggttctt aacagagatg ggtagacagc cttggattgt tcgtggttat
     4621 atgcgcgtgg cagaagcagc aacacaagca ggcggaataa ccttcgttac aattttattt
     4681 ggcatattgt acatcatttt aatgtataca tgtgcatacg tattaattcg tatgtttaaa
     4741 aataaaccgg cgtatgaaga tgtaaatcgc ttagccaaga agcaaggagg agaaatagaa
     4801 aaatgattta tgcatttata ggtataacag tgttatggtt gtttttattt tgctatatca
     4861 ttattgcttc tatagatttt ggggcaggtt tcttcgcatt gcattcaaag ttaactggtg
     4921 atgaaaagaa aattaatcac ttaatttcac gttatttgaa cccagtttgg gaagttacga
     4981 atgtattctt tgttttcttc ttcgtaggat tcgtaggttt ctttccagag tcaatcaaat
     5041 atttaggcac ggtattgtta ataccaggtt cgatagcact gattatgata tcgttgagaa
     5101 acagttttta tgcatttgaa aattatggtc aagatacaaa attagcatgg atgatcatgt
     5161 atggggtaag tggattatta attccagctt cattatctac tgctttaact attacagaag
     5221 gtggctatat taatgttcga aacaatgtta tcgatctaga ttgggtgcag ttactattaa
     5281 gcccatttgc ttggtctgta gtattcttgg caattatttc agttttatat atttcatcag
     5341 gatttttgac atattatgct aaaaaagcaa atgacgaacc agcatataat ttaacaagac
     5401 aatggcacat atttttaggg ccgccgatga ttatcatttg tttattcgta tttctatcat
     5461 tacgcattca aaattctgaa catttttatt cagctgtttt tgactactgg tggatgtttg
     5521 ctataagttt cttattcttt gcattagctt cattgttaac attctttaag aaaaaacatg
     5581 gtttggcttt tgtatttgtt attttacaaa tgatgttcgc gttctttggc tatggaatta
     5641 gtaaattgcc ttacctttta tatccgtttg taaaaattac agatgcatat gttaatccag
     5701 aaatgggctg gacattagtg attgtcttta ttttaggttt acttttatta cttccatcgt
     5761 taatattatt attaagatta tttgttttcg acaaagaata tgttgaagga aagaaatcat
     5821 aagttgagac gataccccaa ctttcattta cttgcattac tgcatttaga taatttagtt
     5881 ggggtgctca tttataataa ttttaaattt atattttcaa tgaattgatg aaaatcattt
     5941 tatggagggc gagtatgggt aaagaatatg tagtcatcgg tctaggtcgt tttggaggta
     6001 gtatcgttcg tgagttgaat gcattagaca tggatgtaat ggccatcgac catgatgaaa
     6061 atagagtgaa tgaatatagt gatatcgcta ctcatgcggt tgttgcagac acaacagatg
     6121 aagcagttat gaaaagttta ggtatccgta actttgatca tgtcattgtg gcaattggtg
     6181 aaaatattca atcaagtacg ttgacgactt taattttaaa agagttaggt gtaaaaaaag
     6241 taactgctaa agcacaaaat gattatcatg caaagatttt aaataaaatt ggagcagata
     6301 ctgttgtgca ccctgagcgt gatatgggta gacgtattgc gcataatgtt gcgagtgcaa
     6361 gtgtacttga ttatcttgag ttggcagacg agcattctat tgtagaattg aaagcaactg
     6421 aaaagatggc ggggaagtct atcattgatt tagatataag agcacaatat ggaattaaca
     6481 ttattgcaat taaacgaggc aaagagttca tcatttcacc aaatccaaat attaatttag
     6541 aaataggtga tattttaatt atgattggac atgataatga tttaaatcgc tttgaaaaaa
     6601 atattgcgac gagataatcg ggagtgggac agaaatgata ttttctcaaa atttatttcg
     6661 tcgtcccacc ccaacttaca ttgtctgtag aaattgggaa tccaatttct ctttgttggg
     6721 gcccacaccc caactcgcat tgcctgtaga atttcttttc gaaattctct atgttggggc
     6781 ccatccccaa cttgcacatt attgtaagct gacttttcgt cagcttcttt gttggggccc
     6841 ctgactagaa ttgaaaaaag cttgttacaa agtgcatttt cgttcagtca actactgcca
     6901 atataacttt gtagagcatt gaacattgat ttatgtctca agctcatcat atataaagaa
     6961 aaagctacta acaatgtgtg gtgagtttaa ttaaaacttc acttcaaagt tagtagcttt
     7021 ttgattattt attgtttgat tctttttgct cgtttacctt cataatgact ggtaaaatca
     7081 ttggttttct agccgttttt tcaaataaat aaggttgtaa tgtttcaatg atagaagatt
     7141 taatctgatg ccattgaata tctttatttt gatttaactt actaataacg tcagttttga
     7201 ttttgcgttg tgcatcataa attaattgac ctgattctct catatataca aatcctcgag
     7261 aaataatgtc tggaccagaa agtaatttat ttgtattaaa atcaatacta acaacaacga
     7321 taactaaacc ttcctcagat aatagcttac ggtctcttat tacaacatta ccgatatcac
     7381 cgataccact accatcaaca agtacattac cagatggaat gcgaccagct ttacgtgctg
     7441 aatcgtgtgt taaagctaag acatctccaa tatcaaagat gaagacatta tcttcttcaa
     7501 cgccgcattc aacaccagtc tcaccatgtg cttttaacat acggtattca ccatgaatag
     7561 gtaagaaata tttcggcttg attaatcgaa gcattaattg ttgatcacct tgagaaccat
     7621 gccctgaagt atggatgtta gaaatcttgc tgtggataac atctgcacca gctttataca
     7681 aggaattaat cgttctgtta atactttttg tattacctgg gataggtgat gaactaaata
     7741 caacggtatc ttcaggtata attttaattt gcttatgagt accattagca attctagata
     7801 atgctgccat tggttcacct tgagaaccag tacatagtat caataactca tgcttcggta
     7861 cggtattaat tttattaggt tcaataaatg tttcaggtgg tgctttaata taaccaagtt
     7921 ccataccgat tttaatattg ttttccatcg aacgaccgaa cgtaacaatt ttacggttat
     7981 ttttgatagc agcttcaact gcttgttgaa ctcggtaaat attagaagcg aaggtagcaa
     8041 atataatacg acctttacaa ttacggaaga tcttatctac gttttgacca acttcacgtt
     8101 cgcttaaagt aaaatcaggc acaagtgaat ttgttgagtc tgaaagtaaa catagaacgc
     8161 cttcttcgcc taattgagcc attttagcaa tgtttgctgg tttgcctaca ggtgtaaaat
     8221 caaatttaaa gtcaccggta tgaactactt ttccttcagg tgtatctacg atgacgccat
     8281 aagtttcagg aatactatgc gtagttaagt agaaagaaat cgtaaagtgc ttagatttaa
     8341 tcacactgtc ctcattgatt tcatttagtt tagcagtacg taataaatga tgttcttcaa
     8401 gtttattacg gattaaacct aatgctaaag gaccaccata aataggtata ttaagttgtt
     8461 ttaataggaa gggcacaccg cctatatggt cttcgtgacc atgtgttata aataggccaa
     8521 caattttatc ttggttttga actagatatg tgtagtcagg tataacataa tcaatcccta
     8581 ataagttatc atcagggaat ttgatacctg catcgataat gacaatttcg tctttatact
     8641 caactgcata agtattttta ccgatttcac ctagacctcc aagtgcatat acacctactt
     8701 catttggatg taattgtttc attatttagc aatctccaca ttaaagtgtt ctgagttttc
     8761 tttttcgtaa tctaaatgtg cgccctctaa tttagtgata aattcgatat taaaattacg
     8821 atctttcaag taacgacgta cttgttcttc tgtttgagct tcaacataaa gtgattgtgt
     8881 attttcacgc acaattacct cgtctctgtt atgttgataa aaaactttaa atactgccat
     8941 gttaaaaatt cctcctaaga atgtttgttt aatttattgt taaccctagt aaaatcgtat
     9001 tggagtatat atcgataaat tcattccaat catctctata atttaactta ataacgattt
     9061 ggttaataac taggttcatc atgtcgttca ttttaaaaaa ttagtgaaat aacactaaaa
     9121 tttcagttaa atcttatttt acatgatgaa tgataataaa taaagcagtt tatctcacta
     9181 gaaatctaag tatttcgaat aaatgtgcag ttctatttct taaaataaat gtagagatta
     9241 aaaattaatg ttaagaaaga attaaaggat tttatatgaa acggtaaaat ttaaatgagg
     9301 ggataaaaag tttggtagaa aggtgaatat atttaactgt tgtttattcg aaaaagttgt
     9361 acaagaaaaa gcttaggaca tcatatttat cctaagcttt gataattagt aaaaatgtgc
     9421 tttaaacttc tacagcatct gtatgtggtt gtaatgggtg atctttgtca atgtgatcat
     9481 agaacattac accatttaaa tggtcaattt catgttggaa aacaattgct ggatatcctt
     9541 ttagacgtaa ttgtatatca ttaccttcga tgtctttggc tttaattgta attctattat
     9601 gacggtgaac tagaccagca acattatcat cgacactaag gcaaccttca ccagttggta
     9661 aataagcttc ttgaacgcta tgacttacaa tttttgggtt cacaagcata tagtcataag
     9721 atttgccact gccatcatct ggtattaaaa cagcaatcat acgtttagaa atattaattt
     9781 gaggtgcagc caaaccaacg cctgaacgta aaccatatcg tttcgcgatt tcctcatctt
     9841 gactatttac taaaaactct ctcatggcga ttaatgtttc tttttcttct ttagttaatg
     9901 gtaattctaa ctcagctgct ttttgacgca aagttggatg accatctcta atgatgtctt
     9961 tcattgttaa catatattgc accttcctta ttttaatttg ttttagttga atgacagtaa
    10021 aaaggttgtt aagatactca tacattttta tgtgtaaata tctacaaagt taaccaacta
    10081 ctgccaatgt ttattttaga tagtatatgt aaattttcag atatgctaat tgcttaaaaa
    10141 atgattaaaa tgttgatttc aagcaatgat actttagaaa tttatttatc atcttgactt
    10201 taaaaattat attataaatg acgtaactgt caacagatat acttagtaat gaagatgtgt
    10261 aatgtaattg tttaaaattg atttccaagc agattttatt tatcatttaa tttaaatagc
    10321 aagtggaggt acaagtaatg aaatttggaa aaacaatcgc agtagtatta gcatctagtg
    10381 tcttgcttgc aggatgtact acggataaaa aagaaattaa ggcatattta aagcaagtgg
    10441 ataaaattaa agacgatgaa gaaccaatta aaactgttgg taagaaaatt gctgaattag
    10501 atgagaaaaa gaaaaaatta actgaagatg tcaatagtaa agatacaaca gttcgcggta
    10561 aagcagtaaa agatttaatt aaaaatgctg atgatcgtct aaaggaattt gaaaaagaag
    10621 aagacgcaat taagaagtct gaacaagact ttaagaaagc aaaaagtcac gttgataaca
    10681 ttgataatga tgttaaacgt aaagaagtaa aacaattaga tgatgtatta aaagaaaaat
    10741 ataagttaca cagtgattac gcgaaagcat ataaaaaggc tgtaaactca gagaaaacat
    10801 tatttaaata tttaaatcaa aatgacgcga cacaacaagg tgttaacgaa aaatcaaaag
    10861 caatagaaga gaactataaa aagttaaaag aagtatcaga taagtatacg aaagtactaa
    10921 ataaggttgg taaagaaaag caagacgttg atcaatttaa ataattaata taatacagat
    10981 ggtaggaaac aactaataca gttcctatta tctgtatctt tttttattaa aacagaactt
    11041 tttcaaatgg tttaacagtc ccatttattt gtggtacaat tagtaaggat aaaatgaatt
    11101 tctatacaat tatgggaaag gtatggtgaa ttgaatggct cctaagttac aagcccaatt
    11161 cgatgcagta aaagttttaa atgatactca atcgaaattt gaaatggttc aaattttgga
    11221 tgagaatggt aacgtcgtaa atgaagactt agtacctgat cttacggatg aacaattagt
    11281 agaattaatg gaaagaatgg tatggactcg tatccttgat caacgttcta tctcattaaa
    11341 cagacaagga cgtttaggtt tctatgcacc aactgctggt caagaagcat cacaattagc
    11401 gtcacaatac gctttagaaa aagaagatta cattttaccg ggatacagag atgttcctca
    11461 aattatttgg catggtttac cattaactga agctttctta ttctcaagag gtcacttcaa
    11521 aggaaatcaa ttccctgaag gcgttaatgc tttgagccca caaattatta tcggtgcaca
    11581 atacattcaa gctgctggtg ttgcatttgc acttaaaaaa cgtggtaaaa atgcagttgc
    11641 aatcacttac actggtgacg gtggttcttc acaaggtgat ttctacgaag gtattaactt
    11701 tgcagcagct tataaagcac ctgcaatttt cgttattcaa aacaataact atgcaatttc
    11761 aacaccaaga agcaagcaaa ctgctgctga aacattagct caaaaagcaa ttgctgtagg
    11821 tattcctggt atccaagttg atggtatgga tgcgttagct gtatatcaag caactaaaga
    11881 agcacgtgac cgcgcagttg caggtgaagg tccaacatta attgaaacta tgacatatcg
    11941 ttatggtcct catacaatgg ctggtgacga tccaactcgt tacagaactt cagacgaaga
    12001 tgctgaatgg gagaaaaaag acccattagt acgtttccgt aaattccttg aaaacaaagg
    12061 tttatggaat gaagacaaag aaaatgaagt tattgaacgt gcaaaagctg atattaaagc
    12121 agcaattaaa gaggctgata acactgaaaa acaaactgtt acttctctaa tggaaattat
    12181 gtatgaagat atgcctcaaa acttagcaga acaatatgaa atttacaaag agaaggagtc
    12241 gaagtaagcc atggcacaaa tgacaatggt tcaagcgatt aatgatgcgc ttaaaactga
    12301 acttaaaaat gaccaagatg ttttaatttt tggtgaagac gttggtgtta acggcggtgt
    12361 tttccgtgtt actgaaggac tacaaaaaga atttggtgaa gatagagtat tcgatacacc
    12421 tttagctgaa tcaggtattg gtggtttagc aatgggtctt gcagttgaag gattccgtcc
    12481 ggttatggaa gtacaattct taggtttcgt attcgaagta tttgatgcga ttgctggaca
    12541 aattgcacgt actcgtttcc gttcaggcgg tactaaaact gcacctgtaa caattcgtag
    12601 cccatttggt ggtggcgtac acacacctga attgcacgca gataacttag aaggtatttt
    12661 agctcaatct ccaggtctaa aggttgttat tccttcaggc ccatacgatg cgaaaggttt
    12721 attaatttct tctattagaa gtaatgaccc agtcgtatac ttagagcata tgaaattgta
    12781 tcgttcattc cgtgaagaag tacctgaaga agaatataca attgacattg gtaaggctaa
    12841 tgtgaaaaaa gaaggtaatg acatttcaat catcacatac ggtgcaatgg ttcaagaatc
    12901 aatgaaagct gcagaagaac ttgaaaaaga tggttattct gttgaagtaa ttgacttacg
    12961 tactgttcaa ccaatcgatg ttgacacaat tgtagcttca gttgaaaaaa ctggtcgtgc
    13021 agttgtagtt caagaagcac aacgtcaagc tggtgttggt gcagcagttg tagctgaatt
    13081 aagtgaacgt gcaatccttt cattagaagc acctattgga agagttgcag cagcagatac
    13141 aatttatcca ttcactcaag ctgaaaatgt ttggttacca aacaaaaatg acatcatcga
    13201 aaaagcaaaa gaaactttag aattttaata cattttaaaa gttaacgaag ttagcgtatt
    13261 ttagtctcat tgattaaaat gaaatgttta atttacgaaa tcttaggagg gcaaaaacgt
    13321 ggcatttgaa tttagattac ccgatatcgg ggaaggtatc cacgaaggtg aaattgtaaa
    13381 atggtttgtt aaagctggag atactattga agaagacgat gttttagctg aggtacaaaa
    13441 cgataaatca gtagtagaaa tcccatcacc agtatctggt actgttgaag aagttatggt
    13501 agaagaaggt acagtagctg tagttggtga cgttattgtt aaaatcgatg cacctgatgc
    13561 agaagatatg caatttaaag gtcatgatga tgattcatca tctaaagaag aacctgcgaa
    13621 agaggaagcg ccagcagagc aagcacctgt agctactcaa actgaagaag tagatgaaaa
    13681 cagaactgtt aaagcaatgc cttcagtacg taaatacgca cgtgaaaaag gtgttaacat
    13741 taaagcagtt tcaggatctg gtaaaaatgg tcgtattaca aaagaagatg tagatgcata
    13801 cttaaatggt ggtgcaccaa cagcttcaaa tgaatcagct gcttcaacta caagtgaaga
    13861 agttgctgaa actcctgcag cacctgcagc agtatcatta gaaggcgact tcccagaaac
    13921 aactgaaaaa atccctgcta tgcgtagagc aattgcgaaa gcaatggtta actctaagca
    13981 tactgcacct catgtaacat taatggatga aattgatgtt caagcattat gggatcaccg
    14041 taagaaattt aaagaaatcg cagctgaaca aggtactaag ttaacattct taccatatgt
    14101 tgttaaagcg cttgtttctg cattgaaaaa atacccagca cttaatactt cattcaatga
    14161 agaagctggt gaaattgtgc ataaacatta ctggaatatc ggtattgcgg cggacactga
    14221 tagaggttta ttagtacctg tagtgaaaca tgctgaccgt aaatctattt tccaaatttc
    14281 tgatgaaatt aatgaattag ctgttaaagc acgtgatggt aaattaacag ccgatgaaat
    14341 gaaaggtgca acatgcacaa tcagtaatat cggttccgct ggtggacaat ggttcactcc
    14401 agttatcaat cacccagaag tagcaatctt aggaattggc cgtattgctc aaaaacctat
    14461 cgttaaagat ggagaaattg ttgcagcacc agtattagca ttatcattaa gctttgacca
    14521 cagacaaatt gatggtgcaa ctggccaaaa tgcaatgaat cacattaaac gtttattaaa
    14581 taatccagaa ttattattaa tggaggggta aaacatggta gttggagatt tcccaattga
    14641 aacagatact atagtaatcg gagcaggtcc tggtggatac gttgcagcaa ttcgtgcagc
    14701 tcaattagga caaaaagtaa caatcgttga gaaaggtaat cttggtggtg tttgcttaaa
    14761 cgtaggatgt attccttcaa aagcattact acatgcttct caccgttttg ttgaagcaca
    14821 acattctgaa aacttaggtg ttattgctga aagtgtttct ttaaacttcc aaaaagttca
    14881 agaattcaaa tcatcagttg ttaataaatt aactggtggt gttgaaggct tacttaaagg
    14941 taacaaagta aacatcgtta aaggtgaagc atatttcgta gataacaata gcttacgtgt
    15001 tatggacgaa aagagcgcac aaacatacaa ctttaaaaat gcaatcattg caacaggttc
    15061 aagaccaatt gaaattccta atttcaaatt cggtaaacgt gttatcgact caacaggtgc
    15121 tttaaactta caagaagtac caggtaaatt agttgtagtt ggtggaggat acattggatc
    15181 agaattaggt acagcatttg ctaactttgg ttcagaagta acaatccttg aaggtgctaa
    15241 agatatctta ggtggcttcg aaaaacaaat gacacaacct gttaaaaaag gtatgaaaga
    15301 aaaaggtgtt gaaatcgtta ctgaagctat ggctaaatct gctgaagaaa cagataacgg
    15361 agttaaagtt acttatgaag ctaaaggcga agagaaaaca atcgaagctg attatgtatt
    15421 agtaactgta ggtcgtcgtc caaacacaga cgaattaggc ctagaagaat taggtgttaa
    15481 attcgctgac cgtggattat tagaagttga taaacaaagc cgtacgtcta tcagcaatat
    15541 ctatgcaatt ggtgatatcg ttccaggttt accacttgct cacaaagcta gctatgaagc
    15601 taaagttgct gctgaagcaa ttgatggtca agctgctgaa gttgattaca ttggtatgcc
    15661 agcagtatgc tttactgaac cagaattagc tacagttggt tattcagaag cgcaagctaa
    15721 agaagaaggt ttagcaatta aagcttctaa attcccatat gcagcaaatg gtcgtgcatt
    15781 atcattagat gatactaacg gatttgttaa acttattaca cttaaagaag atgatacttt
    15841 aatcggtgct caagtagttg gtactggtgc atcagatatt atctctgaat taggtttagc
    15901 aattgaagct ggtatgaatg ctgaagatat cgcattaaca atccatgcac atccaacatt
    15961 aggtgagatg actatggaag cagcagaaaa agctatcgga tacccaatcc atacaatgta
    16021 ataactgatt atctataaag attcagtcat taaaagctgt agcatatgct acggcttttt
    16081 tgttttaggt aaagtaatgt aaggaaattg atttgagata tcgttaacat gtgacatgca
    16141 tgttatacta gcgatgctaa caaaagaatt gaaatggagg gttcaacaat ggaatatgag
    16201 tatccaattg atttagactg gagtaatgaa gagatgattt cagtgataaa tttctttaat
    16261 catgtagaga agtattatga atccggcgtg acggcaggcg actttatggg tgcatataaa
    16321 agatttaaag aaattgtgcc tgctaaagca gaggaaaaac aaatttttaa tactttcgaa
    16381 aaaagtagtg gctataatag ttacaaagca gttcaagatg taaaaactca ctctgaagaa
    16441 caaagagtaa cagctaaaaa ataattcgtt cgaaattaac acaatttaat aggaattttt
    16501 ctttaaaact attgctaata aagctatatt ttgatacctt tatcaagtgt taaacaaaat
    16561 gtttgataaa agtaaactta atatagcttt tttaggtgga aaaataaatg aacataggta
    16621 ataaaattaa aaatcttaga agaattaaaa atttaacgca agaagaactt gctgaacgta
    16681 cagacttatc gaaaggctac atttcacaaa tagaaagtga acatgcctca ccaagtatgg
    16741 aaactttctt aaatattata gaggtgttag gaacgacgcc aagtgaattt tttaaagaca
    16801 gtgaaaatga aaaagtatta tacaagaagg aagaacaagt tatttatgat gagtatgatg
    16861 aaggttatat attaaattgg ttagtttcaa agtcaaatga atatgatatg gagccattaa
    16921 tattaacttt aaagcctggc gcatcatata aaaattttaa tccatcagag tctgatacgt
    16981 ttatttattg tatgtcaggt cagataacac ttaatttagg caaagaggta tatcaagcac
    17041 aagaagaaga cgttttgtat tttaaagcac gagataatca tcgtttgtca aatgaatcaa
    17101 acaatgaaac acgaatactt attgtagcga cagcttcata tttatagggg ggatcttatt
    17161 tggaaccgtt attatcatta aaatcagtta gtaaaagcta tgatgatctt aatatcttag
    17221 atgacataga tattgatatt gaatcaggat acttttatac attattaggt ccttcaggtt
    17281 gtggtaaaac aacaatttta aaattaattg cagggtttga atatcctgac agtggtgaag
    17341 tgatttatca aaacaaacca attggtaatt taccaccaaa taaacgtaaa gtgaatacag
    17401 tctttcaaga ttatgcatta tttccacact taaacgtcta tgataatatc gctttcggtt
    17461 tgaaattaaa aaaattatca aaaaccgaaa ttgatcaaaa agtaactgag gcattaaaat
    17521 tagttaagct ttcaggttat gaaaaaagaa atattaatga aatgagtggc ggacaaaagc
    17581 aacgtgttgc aattgcacgt gctatcgtaa atgaaccaga aatattatta ttagatgaat
    17641 ctttatccgc attagatttg aaattgcgca ctgaaatgca atatgaatta cgggaattgc
    17701 aatctagatt aggtattaca tttatatttg taacacatga tcaagaagaa gcgttagcac
    17761 taagtgactt tctttttgta ttaaaagatg ggaaaattca acaatttggt acgccaacgg
    17821 atatatatga cgaaccagtg aatcgatttg tagctgattt tattggagaa tctaatattg
    17881 ttgaaggacg catggttaga gattatgtcg tgaatattta tgggcaagat ttcgaatgtg
    17941 tcgatatggg tattcctgaa aataaaaaag tagaagtcgt tattcgacca gaagatatat
    18001 cattaatcaa agctgaagaa ggattattta aagcaactgt tgattctatg ttatttagag
    18061 gggtccacta tgaaatatgt tgtatagaca ataaaggtta tgaatgggta atacaaacga
    18121 ctaaaaaagc tgaagtaggc agtgaagttg gtctttattt tgatcctgaa gccattcata
    18181 ttatggttcc tggagaaaca gaagaagagt ttgataaacg tattgaaagc tatgaggaag
    18241 tagacaatgc gtaatactaa taaatttctc ttaatcc
//
LOCUS       DAPSKH010000055        17232 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPSKH010000055 DAPSKH010000000
VERSION     DAPSKH010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 17232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17232
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.055"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            87..1916
                     /locus_tag="RPH49_002068"
     CDS             87..1916
                     /locus_tag="RPH49_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDY5125197.1"
                     /translation="MFNQFKRLIIGQPKKNRELKDEKISKFKGLAILSSDALSSVAYG
                     PEQILITLSVVGAVATWYTLPIAGAVLILLAALIMSYRQIIYAYPKGGGAYMVSKTNL
                     GEKWGLLAGGSLLVDYILTVAVSISSGADAFVAAFPSLYGHKVLIACLLVLFILILNL
                     RGLTESATVLSYPVYLFIIGLVILIFIGTFRVATGDIQPHMHASVGTAVPGVTLFLLL
                     KAFSSGASSLTGVEAISNAVTNFREPSANNAVKTLIAMGSILAFLLVGIVGLAYVYGI
                     MPQTETTVLSQLAMQIFGDNAAFYFVQATTVMILVLAANTGFTAFPMLAASMSKDKYM
                     PRMFTVRGDRLGYSNSIIILGVLAIILIIVFDGMTEDLIPLYAVGVFIPFTLAQFGMV
                     IKWIHERPKNWLSKLSVNLLGGIVTFIVFMILLITKFSQVWPILIFLPFVVIFFLKIN
                     KHYRDIAEQLRSDIDVLNVDVVDRNLAIVPITSITTAVDKSIYYAQMLANNDVIAVHV
                     SFGDEDEKAFQEKWKRHFPDVRLVILHSEYRSIIRPISRFIDKINRKANDQNYMITVV
                     IPEFITKKRWHNLLHNQTSLRMKLYLIYQKNVNVCTIPFKLKK"
     gene            complement(2056..4134)
                     /locus_tag="RPH49_002069"
     CDS             complement(2056..4134)
                     /locus_tag="RPH49_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDY5125198.1"
                     /translation="MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIP
                     IQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYF
                     IHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGII
                     SFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVIVRIRIDLTANKGLKDNN
                     TLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWN
                     TFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFIWVYFW
                     YKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITQG
                     QAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIE
                     HFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPDNQNTKELKRLEDIAKVIETSTLE
                     RLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKE
                     SKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDTSRSLKWRA
                     QRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYN
                     EIVLSLQSKH"
     gene            complement(4272..5681)
                     /locus_tag="RPH49_002070"
     CDS             complement(4272..5681)
                     /locus_tag="RPH49_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5125199.1"
                     /translation="MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLF
                     TYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSM
                     SDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIA
                     MVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGV
                     TAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIG
                     VPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSML
                     VSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKN
                     SKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAE
                     KLAYEQRQNDSGHFRYDNQ"
     gene            5968..6774
                     /locus_tag="RPH49_002071"
     CDS             5968..6774
                     /locus_tag="RPH49_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDY5125200.1"
                     /translation="MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDI
                     SNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKRMSQCLVGKPF
                     IVNEEWAIIGHTGWYDYSFAAQRFSLDELQKGKHYGATWQDKERISWGISDQNLSKIA
                     VEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDI
                     PYSIMGHVHFRKSVMDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI"
     gene            complement(6837..7493)
                     /locus_tag="RPH49_002072"
     CDS             complement(6837..7493)
                     /locus_tag="RPH49_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDY5125201.1"
                     /translation="MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEI
                     MRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDL
                     KGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPL
                     WSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
                     "
     gene            7606..8079
                     /locus_tag="RPH49_002073"
     CDS             7606..8079
                     /locus_tag="RPH49_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDY5125202.1"
                     /translation="MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIA
                     DLQLKNNVDLVGILGLCIPELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQ
                     GAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG"
     gene            complement(8202..9413)
                     /locus_tag="RPH49_002074"
     CDS             complement(8202..9413)
                     /locus_tag="RPH49_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HDY5125203.1"
                     /translation="MQSSSSKTKQFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDF
                     GSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILITFILASGLSVFVTQL
                     PLFLTLRLIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGL
                     ALSVATWRAIFTILTIVALIILIGVASQLPKTPKEELKQVNFSSVIKDFGSLLKKPAF
                     IIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLV
                     EKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMA
                     MEERTGGSGNASSLLGLFQFILGGTVAPLVGLKGEFNTSPYMIIIFITAILLVSLQII
                     YFKMIKKQHVA"
     gene            complement(9592..10251)
                     /locus_tag="RPH49_002075"
     CDS             complement(9592..10251)
                     /locus_tag="RPH49_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125204.1"
                     /translation="MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPER
                     YYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDP
                     KVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADS
                     KLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDDNGGA
                     N"
     gene            complement(10311..11453)
                     /locus_tag="RPH49_002076"
     CDS             complement(10311..11453)
                     /locus_tag="RPH49_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDY5125205.1"
                     /translation="MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIP
                     MADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDL
                     LEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVKFTDV
                     NGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGA
                     DAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVV
                     FDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENY
                     QHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ"
     gene            11721..12107
                     /gene="gtxA"
                     /locus_tag="RPH49_002077"
     CDS             11721..12107
                     /gene="gtxA"
                     /locus_tag="RPH49_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase GtxA"
                     /protein_id="HDY5125206.1"
                     /translation="MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHI
                     TGFIVAFVISYYLNCYFVYRVKPTWRKFISFPITQLVNVSLQTVLLYVFVSWLNLPAE
                     IAPFAGLVITIPITFILSKWILKDSN"
     gene            12241..12348
                     /locus_tag="RPH49_002078"
     CDS             12241..12348
                     /locus_tag="RPH49_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDY5125207.1"
                     /translation="MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK"
     gene            13052..14815
                     /locus_tag="RPH49_002079"
     CDS             13052..14815
                     /locus_tag="RPH49_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125208.1"
                     /translation="MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVF
                     KIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQ
                     KLMRLPLGIVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSATIFLYIMLID
                     WRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQ
                     SQSSYKKYKDAVDNYKIHTLNWFKNTWRYMNLGASVLPSTFLGILPVGMYLISINQLN
                     YAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQH
                     YEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVT
                     SGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAK
                     LAQCHEFIKKLPDGYDTNVGTVGDELSGGEKQRVTIARMILKDAPIIVLDEATAYVDP
                     DNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLLKLNGN
                     YKKMWDTHMHTKDWGINTGHN"
     gene            14840..16573
                     /locus_tag="RPH49_002080"
     CDS             14840..16573
                     /locus_tag="RPH49_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125209.1"
                     /translation="MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIF
                     NNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKL
                     KNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQ
                     VSLLACIGVLLSFLAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKEN
                     TSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLP
                     TLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNEN
                     IAFQNVNFSYDDKQVIKNVNFEVPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIR
                     IDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRVAKQACCH
                     DFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQL
                     IQTAINELSKGKTVITIAHKLETIKNADQIIVLNDGEIIQRGSHNELIQKPGMYQDFI
                     RIKSKSAGWKL"
     gene            16981..>17232
                     /locus_tag="RPH49_002081"
     CDS             16981..>17232
                     /locus_tag="RPH49_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125210.1"
                     /translation="MYKNYNMTQFTLPIETSVRIPQNDISRYVNEIVETIPDSEFDEF
                     RHHRGATSYHPKMMLKIILYAYTQSVFSGRRIEKLLHDSI"
BASE COUNT         5907 a         2590 c         3081 g         5654 t
ORIGIN      
        1 aaaaatatta attaactctc tatacttttc ggaaagatag gcgtatagtg atatccatca
       61 aaaagtataa aaaggaatag gagattatgt tcaatcaatt taaaagactt attatagggc
      121 aacctaaaaa aaacagagaa ctaaaagacg aaaagatatc gaagtttaaa gggttagcga
      181 ttctttcgtc tgatgcatta tcttcagtgg cttacggtcc cgaacaaata ctgattacat
      241 tatcagtagt gggtgcagtt gcaacttggt atactttacc gattgcaggt gctgttctga
      301 tcttattagc tgctttaatt atgtcttata ggcaaattat ttatgcatat cctaaaggtg
      361 gcggcgctta tatggtgtcc aagaccaatt taggagaaaa atggggattg cttgcaggag
      421 gctcattatt agtcgattac atactgactg tcgctgttag tatatcatct ggtgctgatg
      481 catttgttgc tgcattccca agtttatatg ggcataaagt actgattgca tgtttacttg
      541 tactttttat tttaatatta aatttacgtg gtttaactga atctgccacc gtattatcct
      601 atccagtata tcttttcatt atagggttag tgatattaat atttataggt actttccgtg
      661 tggcgacagg agatattcaa ccacatatgc atgcatcagt aggaactgcg gttcctggag
      721 taacattatt cttgctatta aaagcatttt catcaggggc ttcatcatta acaggtgttg
      781 aagctatttc aaatgcggta accaatttta gagaaccaag tgctaataat gctgtaaaaa
      841 cgttaattgc tatgggttca attttagcgt ttttattagt tggtatcgtt ggtttagcat
      901 atgtttatgg gattatgcca caaacggaaa cgacagtttt atcacaatta gctatgcaaa
      961 tatttggtga taatgctgcc ttctattttg tacaggcaac gactgtgatg attttggtat
     1021 tagcagccaa cactggattt acagcttttc cgatgttagc ggcttcaatg tctaaagata
     1081 aatatatgcc tagaatgttt actgttagag gtgatcgctt aggctactct aactcaatta
     1141 ttattttagg tgtattagcc atcattttaa ttattgtatt tgatggtatg actgaagatt
     1201 taattccatt gtatgctgtt ggtgtattta ttccatttac actagcacaa ttcggtatgg
     1261 ttattaaatg gattcatgaa cgtcctaaga attggttgag taagttgtct gtgaacttac
     1321 ttggtggtat cgtgacattt attgttttta tgattttact cataactaaa tttagccaag
     1381 tatggccgat acttattttc ttgccgttcg tggtgatttt cttcttgaaa attaacaaac
     1441 attatcgaga tatcgcagaa caattacgtt ctgacattga tgttcttaat gtggacgtgg
     1501 tagatcgtaa tttagcaatt gtgccgataa caagtattac aacagcagtt gataagtcta
     1561 tttattacgc acaaatgctt gcgaataatg atgtcattgc ggtacatgta tcatttggag
     1621 atgaagatga aaaagcattc caagagaaat ggaaacgtca tttcccagat gtaagattag
     1681 ttattttaca ctcggaatat cgcagtatta tacgaccaat ttcacgtttt atcgataaga
     1741 ttaatcgtaa agccaacgat caaaactata tgattacagt agtgatacca gaatttatta
     1801 ctaagaaacg ttggcataat ttattacaca atcaaactag tttgcgtatg aaattgtatt
     1861 taatttatca aaagaatgtt aacgtatgta caattccatt taaacttaaa aaatagattc
     1921 tataatcaaa tcggattgat gaaaggttat ttacttttcg tcaatccgat tttttgatgt
     1981 tgaatataaa caccccgtac atatgagatg ataatgactt tgtctcatat gtacgggggt
     2041 gttgttatgt cttgcttaat gtttggactg taaagacaag acaatttcgt tgtaattgat
     2101 attttctcga atttgagctg caacgatatt gttgattttg tttttgcgaa ttaattcatc
     2161 taaaagatga cgttgtaagt acaatgcttc caatttgtgg ttatggaaca tagcttgcgg
     2221 tatgatttga ttgctgtttt cttgacgttc ttttcgacgt tgtgcacgcc actttaatga
     2281 gcgactcgta tcatagtaat gattaatgac taaactaacc tcaagtacat ttgtactatt
     2341 ttgttcttct tttaagcgta aaataatatt gtgattcaca atacgcataa ttttttgaac
     2401 atctttgaat gaattttcaa attcttgctt cttagattct ttgtttaagg ctttgtagtg
     2461 cttcatcgct ttaagtctaa gccataacat cttgaagaag tttgcaaatt tttcaacaaa
     2521 tgaagcagta cggtgtgtct ctgttaattc gacaatattg cggtaattat ttatatcttg
     2581 atatgttgcc ttacctttat caattaaacg ctcaagtgta gatgtttcga ttacttttgc
     2641 aatatcttct aaacgtttga gttcttttgt attttgatta tcaggttctg aatttaataa
     2701 aaataacaat tctccatagt attggtttaa tactgggcga taatttgtat cgtttttgtc
     2761 ttttttactt tcgtttttaa aatgttcgat aactttttgg acaatgaaaa ttttggcaga
     2821 ttgataagtc atacctttaa aagtagtatc ttcggcagat ggtgtaatta aaggtaaaac
     2881 aatttgcgct aaaattaaac taattaatac catgaatgat gcaataaaca atagatcatt
     2941 acggtattca aaagcttgcc cttgtgtaat aataaacggc aatgttaagg ccatagataa
     3001 cgaaatggtc ccgtgtatgc cacacatcgt catgataaaa gcgtaacgta cacgagaagg
     3061 tggtgtttca tgtgaatcat gttcctcatc taggtatgat tggatatttt tcgggaaata
     3121 aaaatcttta taccaaaaat aaacccagat aaaacggcag gcgtaaattg ctatagcgat
     3181 taatatagta atcactatta aaaatgaaaa gttgtccggc tctgtttgga aaatatctat
     3241 gactacagta ggaatcataa aacctaatac aacaaataca aaaccattta aggcataact
     3301 aaatgtgttc caaatttgat ggtaattcat ttgtagttcc gtttgtgctc taattaaacg
     3361 gtcgcgttct aaaccatgga ttagacctgc gattacaact gcaatgatac ctgaagcatg
     3421 aacttcttct gctaaaaagt atacgacaaa aggtgttaat aattgaataa aagttaaggt
     3481 attgttatct tttaaacctt tattagcggt taagtctata cgtattctaa cgataacgaa
     3541 tccaataatt gcaccaataa gtacacctag tattgttgaa atgataaatt gttcaacagc
     3601 ttggaataat gaaaaggtac cagttactaa tgcagtaaca gcaattttaa atgaaatgat
     3661 acctgctgca tcattgagta aagattcacc ttctaaaatc gtcatagaac ctttaggtaa
     3721 taattttccg cgtgtaatag cagatactgc tactgcatca gtaggacata aaattgctgc
     3781 tattgcaaaa gcggctggca ttggtaaggc aggccaaatc caatgtataa aatagccaac
     3841 accgactaca gttgcaaata ctagtgccat tgacattaat agtataggtt tacgatattc
     3901 tagtaatttt gttcgagaga cgtgggtacc ttccacaaaa agtagtggcg cgataacggc
     3961 aaacataaat acttcagaat tgaattggaa atcaacttgt ataggaataa tgaaaataac
     4021 gacacctaat gcaatttgaa taaaggcagt aggaatttgt gggaatcgat tattgataac
     4081 cgaactaata atcacagcaa aaataaaaat taaaaatgct tctaatagtg ccatacaata
     4141 ctcctcaaaa ttttaatagt taatatttta tcacttttaa ggcataatga catagatata
     4201 ttgataaaat gaagttattt tcaaaaaaac tctagtatcg gttgaactga tactagagcg
     4261 agatgtttaa attattgatt gtcatatctg aaatgaccgc tgtcattttg tcgttgttca
     4321 tacgcgagct tttcagcatt cgttttgtat tttttataaa agaaaaataa aaatataaac
     4381 cagaatggcg aaatataaat agctgctctt gtttcgtcac taaagaataa taaaatgaat
     4441 acaaagaaga agaacgctag aataatgtaa gcaataggct taccaccaat caacttaaat
     4501 ttactgtttt tatgtgcctc aggatgcttt ttcaaataca ttagataagc gacaataatc
     4561 attgcccaaa caactaaaaa caacacagtt gataacgttg taacgtatat gaatagttga
     4621 attgcattag ggaaaatgta gtttaacaaa gctgctataa gtaatgcaat tgatgaaact
     4681 aacattgata aataaggcac gccatgacta ttcgttttat ttaaaacttt aggacctaac
     4741 ccttgttgtg acagtccgaa taagatacga ctattcgaat agataccact atttgtagca
     4801 gaggccgcgg cagttagcac gacaaagtta acgacacctg ctgcaaatgg cacgccgatt
     4861 aatgtaaaga gtttaacgaa agggctacta tttggatcga tatcattcca aggtatgact
     4921 gacataatta ctaatagacc accgatatag aataataaaa tacggatagg tacattatta
     4981 attgctttcg gtaaggtttt ttcaggatct ttcgtttcac cagcagttac acctataagt
     5041 tcaataccaa tgaatgaata tacagcaatt tggaatgaca ttaagaaacc aaatgttcca
     5101 ccagggaaca tgccaccgtg actgattaag tttgtgaatg atgcatgtcc ataatgtgtt
     5161 ttaaatgaga aaaagattaa tacaagacca acgataacca tcgcaataat tgtgacaact
     5221 ttaataatag agaaccaaaa ctccagttca ccaaataatc tggcacctaa taagttgaag
     5281 ctaatcaaga ttaaaacaat aaatagcacg gtaatccaat ttgggacttg tggataccaa
     5341 aatgcaaagt attgtcccat cgcagttagg tctgacatac ttgatacaat ccaacataac
     5401 cagtaagtcc agccaatgac aaagccacca aaagggccta aatattcatt tgcaatatca
     5461 acaaatgaat taaatcttgt attgctcaac aacaattcgc ctaatgcgcg cataaaagcg
     5521 aatagtacaa ccccaataat catgtatgtg aataacagtg atggaccagt taaagatatt
     5581 gtttgacctg atcctaggaa taacccagtt ccaattgcgc ccccaattgc tatcaattgg
     5641 atatgtctgt tattcaactc tctatgcaat tttcttgcca taattttcct cctcaggata
     5701 aagcaaataa aaaagttgtg tgtaagcgtt ttcttaatta taaatactaa agaaatccat
     5761 ttaataaagc aattattttt ttaaatataa gaaaaaacat ttgataggta agggtatgat
     5821 aactaaaact tatcgatttt tttgaaaaga tataagtttt tatgcaaaaa tataaaataa
     5881 tcatctaaat gaagcagtta actatatata ttagataagc tatggcataa taaataacat
     5941 tttaatttga gtaaagaagg tatgggtatg aagataggga caatcgccga tttacatatt
     6001 gatcgtcata ataaaaaaac atccgaagat tacttagagg cattggttga aatagttaag
     6061 tataagaaat tggatatatt gttgattgcg ggggatatct caaatcatta tcaattgacg
     6121 caccaattta taacgcaatt gacaaaacaa ttagatatac ctgtgaaatt tgtacctgga
     6181 aaccatgatt tatgggaagt tgaaagtatg actacgcaag acatttggaa taattataag
     6241 aggatgtcac agtgcttggt aggaaaacca tttatagtaa atgaagaatg ggcaatcata
     6301 ggacatactg gttggtatga ttatagcttt gcagcacaac gattttcatt agatgagtta
     6361 caaaaaggaa aacattatgg tgcgacttgg caagataaag aacgaatatc ttggggcata
     6421 tcagatcaaa atttatctaa aatagcggtt gaacaagtga agaaagatat attagaagta
     6481 ggaaatagac gagtgatttt agtcacacat gttgtgacgc accctgattt cattgttcct
     6541 atgccacatc gtatattcga tttttataat gcatttattg ggacaagtga tttcaatcct
     6601 ttgtatgcga tgttcgatat accatatagt attatgggcc atgttcattt tcgtaaaagt
     6661 gtgatggatg atggcagatg ttatctctgt ccgtgtctag gctatccaag acaatggcgt
     6721 tcagaagata tttaccagga aataaatgag acgatacaaa taatagaaat ttaaaatgcg
     6781 caaacctgac ccagtttgcg cattttatgt tttacacacg cgagtaatgt gtttacttac
     6841 gtgtgtttat tttgttgttg attttcaatt gtatatgaat gtggttgcac ataaatgcac
     6901 tttcttcctg gtgaattaaa gctatattcc attttctctt tacgaatttt aataatttgt
     6961 ttgcgatttg gaatgatggc aggtaaaact aggccacgac gaatatgact ccaaagtgga
     7021 tcgatataat agtaataata atcatcgtac ccaatgagta acgttacgtg aatatttgaa
     7081 acttgtttcg ctggcttgtt atcaaagcgg aaaacacgta gtaatggttt agaaccaaga
     7141 ttagtatggt atattaacac aggttgacct tgatcgataa tacctttaag atcttctaag
     7201 gatttaccag tgccgtctac gatattagga ttgtattttt gtaaaaatgg tacatatgct
     7261 tctggaaata tcgtttgatg ataattgcca agcttaatga ataagtgatg tccaacataa
     7321 cctttatgtg gattgttcgg atgtgtcggc caatgtctca taatttctgt agcagggata
     7381 tgttggttat tgtattgcaa catcatggct gcggaaacac cttcacaccc catgaccata
     7441 gggataggaa atagctgact gataggttta actggtaata tttttcggtt cataatatag
     7501 tcctcgcatt gattcaataa atatttaata taattatata gcgtcaatgc aaaatgtcct
     7561 aaacatatgt tttacatgag tgaataaaat taatggagtg ataaaatgga atatcaatta
     7621 caacaacttg cgtcgttaac gttagtaggt attaaagaaa cgtatgaaaa tggacgacag
     7681 gctcagcaac atatagcagg gttttggcaa agatgttatc aagagggagt aattgcggat
     7741 ttacagttaa aaaataatgt tgatttagtc gggatacttg gcttatgtat acctgaatta
     7801 gacggtaaga tgtcatatat gattgcagtt accggagata atagtgctga tattgaaaaa
     7861 tatgatgtca taacattagc aagttcaaag tatatggtat ttgaagcaca gggagcagta
     7921 cctaaagcag ttcaacaaaa aatggaagag gttcatcact acatacatca atatcaagca
     7981 gatacggtaa aatcagcacc attttttgag ttgtatcagg atggtgatac tacaagtgaa
     8041 aaatatatta cagaaatttg gatgcctgtt aaagggtgat tgaatagaaa tgtacttgat
     8101 atgaaggcgt aattttagtt gaagattgga tctcataatt cataaagaag aaccctgaca
     8161 aagatagata tctttgctag ggttctaatt atgttgaagt gttatgcgac atgttgcttt
     8221 ttaatcattt taaagtaaat gatttgtaga ctgactaata gaatggctgt aatgaagata
     8281 ataatcatat atggtgatgt attaaattcg ccttttaagc caactaatgg tgcaacagtg
     8341 ccacctaaga taaattggaa taagccaagt aaacttgatg cgttaccact gccacctgtt
     8401 cgttcttcca tagccattgt gaaaccaagc ggtccaattg acgtcacagg acacacattt
     8461 aagaagaatg cgatgagtaa gacccaaagt ggtaaatgga atgtaagtgt caggataatt
     8521 aaagcaacac ctaccacttg tataatagtt aaaatgatta ataatatgtg gcgatgtaat
     8581 ttttctacta ataaagcaac gacttgactg acaatgatta aacctacacc gttaacagca
     8641 aacatgatac taaattgttg gggtgtcata ttatacaatt tttgagtaat aaatggcgat
     8701 gcagatgaat aactaaatag cattacataa gttaaacctt gtaatagcat tggaataata
     8761 aatgctggtt ttttcaaaag acttccaaaa tctttaatga cgctactaaa attcacctgc
     8821 tttaattctt ctttaggtgt tttaggtaat tgagaagcga cgccaattaa aatgataagt
     8881 gccacaatcg ttaaaattgt gaaaatagca cgccaagttg ctacggataa agctaatcca
     8941 ccggctaatg gtgcaagaat agtgataata ccattaacta ccattaaaga tgctaaaaat
     9001 ttagcgagtg cgttgccact aaatttatca ccagcagagg ctttggcaat aacgatgacg
     9061 ccaccaccag ttaaaccttg aattaaacgt aaagttaaaa atagaggtaa ttgggtaacg
     9121 aacacagata atccggatgc caagatgaaa gtgattaaga tcgatacagc aatacgttta
     9181 cgaccaaagg catcggataa aggtccgaag ataaattgac caagtgcaag accaatcatt
     9241 gtgaatgata aggttaattg aatttctgat gttgtcgaac caaaatcacc ttgcacttta
     9301 ggtaatgatg gtacgtacat atctatagtt agagggccaa aagctgtcat gacacctaac
     9361 gtgattaaca ataaaaatga aaattgcttc gttttggaac tcgaagattg cataaacaga
     9421 ctccttaatt tatataatta tgtaaattat atacgtttta tgtgcatttg tatgtagtta
     9481 gaatataagt ttatataaaa agtcctatac tcgcaatgta tcatcattaa taacgtagtg
     9541 atacagataa agtataggac ttaatgttta tcatcaaagc aggtgtaata attaattagc
     9601 gccaccattg tcatctttaa ataagctttc taatttagat ttaatactgt cgaattttgt
     9661 attaatatca tttaacatgc tttcaatttt accttggctt gcattgtttt taagtgcatt
     9721 atttgcctct gtcaatttgt tgatttggtc ttgataaaat tgagttagct tagaatcagc
     9781 tttgttttgt tcttgctgct tcaagttgtc gatttgattt tgtaaatttt taataatgtc
     9841 atcagttttt tggttgtttt taatattttc tttagcattg tcgacttgct ggttaatttg
     9901 gccgtcttga ttttcaactt gttttttata attttgagag actttagggt cattactaac
     9961 tttatcgcta tcattgttaa gtaaggcgcg tgtgacaaaa atagcgacaa taattaagag
    10021 aatagcaata atgatatata accatttttt tgaacggcgg gatttctcgt tttcttcttc
    10081 aagaatttgt tctcttcgat aatctctacc attatagtat cgttccgggt gttcttcagg
    10141 atcgccttta gcatattgtt gtctatacga tgcgtcttca gattgacgac gatgattttg
    10201 attttgattg tcgtattgat atgaatcacg gtatttatca gttcttttca tgggtttcac
    10261 ctcattcaag ttttaactgc aaataataaa gctgatgatt tactttgaca ttattgtaat
    10321 ttcagaatac gagcaatgtc agttgcagtg tttaataaat tttgttcgct attttgtagg
    10381 acatcttcta aagtgctagg tgaagagatt atagaatagg cactatcaat accgaaatcg
    10441 taaacatgtt gataattttc gcctagactt ccacaaatcg cgatgacagg aatatgatat
    10501 tgttttgcag ctaacgcaac gcctacgggt gttttaccaa agatggtctg ataatccatg
    10561 cgtccttccc cagtaataac gaggtctgca tctttaattc tttgatgaaa atctgtaatg
    10621 tcaaagacga catcaatacc ttttgttaaa gttgtctcac aaaacgctaa taatgctgcg
    10681 cccataccgc cagctgcacc agaacctggt atttgattaa cggactttcc tgtgcacatt
    10741 tttatcttat catgataatg cgacattgcg aaatccaact ttggtatcat ctttgcatca
    10801 gcgccttttt gaggaccata aatataggta gcaccatttt cacccaataa aggatttgaa
    10861 acatcacagg ccactttaaa ggtcacctct tttaatcgcg aatctagatt ggttatatcg
    10921 atttgtgcaa tgtgagcaag attagcacca ttcatttgta ataagtcccc gtttacatca
    10981 gtaaacttta cgcctagtgc acttagcata cctgtaccac catcatttgt tgcactgcca
    11041 ccaatcccta aaataatggt cttagcacca tgatttaatg catctttaat tagttcaccg
    11101 gtaccatatg atgatgtgta taaaggatta cgttcctctt tttctaataa atccaaacct
    11161 gacgctgccg ccatttcaat aattgcaatt tgttgttcgt ctgcgcgtgc ataacatgct
    11221 tcaataggtc gcattaaagg gtcattaacg atgactgtat acttagtggc acctgttgca
    11281 tgcattaaag catctgtggt accttcacca ccatcagcca tcggaatgat atcataatga
    11341 agggtattcc cataaacatt agtaaatgcc tgctttataa tattgccaac ttgctgtgcg
    11401 gtcatacttt ccttaaatga gtcaggagcg atgacaattt tttgtaattg catagtagac
    11461 atcctctcat tactgttgtc gctcttattg tatataaaat tactagtgaa ctaaagtaat
    11521 ctctatagtg ctaatgagtc gcgcgataaa ttagttacat tataatggcg tataaggatg
    11581 aggggaaaga gactaaattt gctgtgaaag ggtataaaaa ttgaagtaag tatatttgaa
    11641 gagaagcgga ttggctcgca tattcgagta tgttggagaa cgtagttata catatatttt
    11701 gatgttgagg agttacacat atgaaactaa cacaaacgca tgctgaaatt ttaaaattta
    11761 tcattgttgg cggcattaat acgttaaatt attatgttgt ctatttattg ctgttaaaat
    11821 tattacacat tgaatatatg attagtcata ttaccggatt tatagtcgct tttgtgattt
    11881 catattattt gaattgttat tttgtctaca gagtaaaacc tacttggaga aaattcatta
    11941 gttttccaat tacgcagctt gtcaacgtaa gcttacaaac agttttatta tatgtttttg
    12001 tatcctggct aaatttgcca gcggaaattg cgccatttgc aggtttagtg attacgatac
    12061 ccatcacatt tatattatct aaatggattt taaaagatag taattaaagt agcgtaaacc
    12121 actaaagaat actttgctca ggcgttaata ttgcgtgaaa tataataaat aaatgatata
    12181 atataatggt cgcctaacat ctcgggcgtt actttaacgc agagaggagg tgtatgacgg
    12241 atgttcaatt tattaattga catcatgact tcagctttaa gcggctgtct tgttgcgttt
    12301 tttgcacatt ggttacgaac gcgcaacaat aaaaaaggtg acaaataacc aacacctaaa
    12361 taaatcccct cactatggca gtagtgaggg gatttggtgt atttagatgt tcaatttatt
    12421 atgtaactaa ttatagcatt gatgaacaag gtgtgcaatg tattttttgc aatattacaa
    12481 taaatgaatt taattatttt agaattaagt atttcgaaaa atgatttaat agttgagtca
    12541 taggatcatt agataaagcg aataatcaat tatagggaca ttgggataca aatcaatgta
    12601 ctagactcta caaggctata ctcagggacc caacatagag aaattggatc cacagtttct
    12661 acagacaatg caagttggcg ggcccccaac acagtagctg gcggaaagtc agcttacaat
    12721 aatgtgcaag ttggcggagc cccaacatag agttttactc atgtattcct atttttaagt
    12781 acatattagc tgtggctaag gataaagaat cattacataa taaatcatta gtggctcttt
    12841 atcatttctg ccccataacc ttgtgaattt ttaaaagaaa tgtgtcacaa atccacgcga
    12901 cattgataat cgttatcaac taatatatga tgtacttgta ataagtatta atttttaaca
    12961 aataacaaat ttatatttta tcatcattca atgaaataaa taatataagt ggcttaattt
    13021 agcttataaa ttgaaaggag ttacatatac gatgaacaat cagacaaatt ggataaagat
    13081 actcagcgga tttgcttctg atagtaaatg gaaaattatg ttatcaattt tgttgtctat
    13141 catcagtgtc ttttctggat tagttccata ttgggcagtc tttaaaatta ttttaatgat
    13201 gattaacaat gcatatacga ttaattcgat tatggtttat atctttattg ctttaatcgc
    13261 ttatatttca caagtgtgtt gttttggagc gtcaacgatg ctatcacata ttacggcata
    13321 tgaaatttta tctgaaattc gtaaaaaatt agctcaaaaa ttaatgcgtc tccctttagg
    13381 catagtggaa tctaagaaaa taggtgaatt aaaaaatata tttgtcgata aggttgaaac
    13441 aatagaatta cctttagcac atatgattcc tgaagttata ggaaacttac ttttgtcagc
    13501 tactatcttt ttatacataa tgctcattga ttggcgtatg gctagtgcct tattagtaac
    13561 gataccaatt tcaattttcg cttttaaaaa agttatgtct ggatttaatg agacatatgc
    13621 tgaacaaatg aaatcgaata attatatgaa tagcgcgatt gtagagttta tcgaaggcat
    13681 tgaagtgatt aaaacattta atcaatctca aagttcatat aaaaaatata aagatgcagt
    13741 agataattat aagattcaca ctttgaattg gtttaaaaat acatggaggt atatgaattt
    13801 aggagctagt gtattacctt caacattttt agggatttta ccggtcggca tgtatttgat
    13861 atctatcaac caattaaact atgcggaatt tttcctatgc atcgtattat ctttaggtgt
    13921 agtagcaccg attaagaatt ttactaatta tgtaaatcat ttaaagtcta tacaatacgc
    13981 attaactgaa gtgaatcaaa tattaagtct agaagagtta gtattgtcaa caaaatttaa
    14041 gaagcctcaa cattatgaaa ttgcttttaa taatgttgga ttttcatata acaaagataa
    14101 ggacgatctg gtctttaagc atttatcatt tacagtacca gaaaataatt tcacagcaat
    14161 cgtcggggca tctggtagcg gtaagtcaac cattgccaag cttatatcac gatactggga
    14221 tgtgacttca ggtgaaatta cgattggcgg tataaatata aaagatattg aatcgaaaca
    14281 acttaacgat ttagttggtt ttgttggaca agataacttt ttattaaatc ttacttttaa
    14341 agaaaatatt aaacttggca atccagaagc tacggatgag gcagttgaaa aagctgccaa
    14401 gttagcacaa tgtcatgaat ttatcaaaaa gttaccagat ggatatgata cgaatgttgg
    14461 tacagtggga gatgaattgt ctggtggtga aaaacaacga gtcactattg caagaatgat
    14521 attaaaagat gcgcctatca ttgtattaga tgaagcgact gcttacgttg atccagacaa
    14581 tgaacaaaaa attcaagaag cattaaatgt gttgacgcag gataaaacat tgattgttat
    14641 tgcacatcgg ttatctacga ttcaacatgc agatcaaatt attgttttag gtaaacaaca
    14701 aattttagaa aaagggtcac atcacttatt gctaaaatta aacggtaatt ataagaaaat
    14761 gtgggatacg cacatgcata caaaagattg gggaatcaat actggacata attaaactaa
    14821 tgagaaaagg aggtcaaata tgtttcaaat tacatttaaa attttaaact ggataagacc
    14881 atataaagca agaatgattt taggatttag catgtcattt ttaaatgcta tttttattgc
    14941 gttacctatc tttttagctg caaaaatatt taataatgtg ctatctcata aacctattta
    15001 tatgaaagat atattgaatg ttgtaattat catggtttta ttagtgattg gacgatttat
    15061 tacagcatat ttcaaaagca aaagccatga gagcatcgct tatgaaatga gtgcgaaaga
    15121 acgtttagat ataggggata aattgaaaaa tgtaaggtta ggttatttta attcgcatca
    15181 ttcaaatgag ttaacaacaa tagtaacaac agatttaacc tttttagaaa actttgctat
    15241 gaaaatggtg gacgttgttg ttaatggata catattaatt acagtactca tattgtctct
    15301 acttgtagtt tcgtggcaag tatcattatt agcatgcatt ggcgtattac tatcattttt
    15361 agctattcaa ttattagaaa gaaagagtcg acaaaatgcg ccagcgtatc ataatgtaca
    15421 aaaccaatta gtggaaaagg tattggaggt tattcgtggt attcaagtaa taaaatcatt
    15481 cgcgaaagaa aatacgagtc ttaaaagttt taaccaagca gtcaatgaaa gtaaacgtat
    15541 aaatacaaaa atagaaatgc aatatatccc attcaattta ttgcatttac ttagtttaaa
    15601 agttgtttca ataatgattg tattagttgc atgcttatta tatatgaatc atagtattga
    15661 tttacctacc cttattatga tttcaatttt ttcatttgtg atatttgata gtgttgaaaa
    15721 cattaatagt gcagcacacg tactcgaaat gatagatatg acgatagatg atattgaaaa
    15781 gataaaaaat gctccagaac tggatgagaa tggaaaaaat ttgacgatta aaaatgaaaa
    15841 tatcgctttt caaaacgtga atttttcata tgatgataaa caagtgataa agaatgtgaa
    15901 ttttgaggta cctacacaaa catcaacagc aataattgga ccttcaggaa gtgggaaatc
    15961 tacattatgt cacttactct tgcgctttta tgatatcgat gatggaaata ttcgcatcga
    16021 tggtgttgat attaaagata tgacattaag tacgttaatg tcgaaaatta gtgcagtatt
    16081 tcaaaaggtg tatttattta atgatacgat tgaaaataac atattgtttg gcaatccagg
    16141 tgcaacgaaa gaagaaatta ttcgtgtagc gaagcaagca tgttgccacg acttcatcat
    16201 gtcattacct gagggatatc aaacaatgct aaatgaaaaa ggtagtaatt tatctggcgg
    16261 agaaaagcaa aggatttcta ttgctagggc gatattaaaa gatgcaccaa taattatttt
    16321 agatgaagca actgcaagta ttgaccctga aaatgaacag ctgattcaaa cggcaattaa
    16381 tgaattaagt aaaggcaaaa cagtaattac aattgcacat aaacttgaaa ctattaaaaa
    16441 tgcagatcag attatagtgc tcaatgatgg tgaaataata caaagaggaa gtcataatga
    16501 attaattcaa aaaccaggga tgtatcaaga ttttataaga ataaaaagta agtcagcagg
    16561 ctggaaatta taaataatag tttaatatgg aatcagaatg tggaaataaa aagggtgata
    16621 gataatcaac agaaaaataa acaggctggg atataaatcc ctaaaaaaaa cagcagtaag
    16681 ataattttca attagaaaat atcttactgc tgttctctat ttatacaata cttcgtattg
    16741 aatggcttcg ctttcctagg gtgccgtctc agcctcggtc ttcgactggc actgctccct
    16801 caggagtctc gccattaata ctacttatta acatgtaatt ttacttttaa atactttaaa
    16861 aaaataagac actttgccca acttgcacat aaatgtaaaa ttcaataaaa tgaattttct
    16921 gtgttgggtc ccttcgtata atttaataaa taccactaaa ctaaattaac gaggtgcctt
    16981 atgtataaaa attataacat gacccaattt acactaccaa tagaaacttc tgttagaatc
    17041 cctcaaaatg atatttcgcg atatgttaat gaaattgttg aaacgatacc tgatagcgaa
    17101 ttcgatgaat tcagacatca tcgtggcgca acatcctatc atccaaaaat gatgttaaaa
    17161 atcatcttat atgcatatac tcaatctgta ttttctggtc gtagaataga gaaattactt
    17221 catgacagta tt
//
LOCUS       DAPSKH010000056        16587 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPSKH010000056 DAPSKH010000000
VERSION     DAPSKH010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 16587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16587
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.056"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            268..1062
                     /locus_tag="RPH49_002082"
                     /pseudo
     CDS             268..1062
                     /locus_tag="RPH49_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1205..1378)
                     /locus_tag="RPH49_002083"
     CDS             complement(1205..1378)
                     /locus_tag="RPH49_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NETI motif-containing protein"
                     /protein_id="HDY5125211.1"
                     /translation="MKFKVNENETIADCLSRMKMQGYMPVKRIEKPVFQEQNDGTVEV
                     SHQEIIFVGKKIQ"
     gene            complement(1359..1961)
                     /locus_tag="RPH49_002084"
     CDS             complement(1359..1961)
                     /locus_tag="RPH49_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDY5125212.1"
                     /translation="MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASV
                     SFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSA
                     EYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFII
                     AYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK"
     gene            complement(2232..3053)
                     /gene="nadE"
                     /locus_tag="RPH49_002085"
     CDS             complement(2232..3053)
                     /gene="nadE"
                     /locus_tag="RPH49_002085"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDY5125213.1"
                     /translation="MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSL
                     VLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVEQALRFIEP
                     DEIVTVNIKPAVDQSVESLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTD
                     HSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKP
                     QLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS"
     gene            complement(3046..4515)
                     /locus_tag="RPH49_002086"
     CDS             complement(3046..4515)
                     /locus_tag="RPH49_002086"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500623.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDY5125214.1"
                     /translation="MYQLEDDSLMLHNDLYQINMAESYWNDNIHEKMAVFDLYFRKMP
                     FNSGYAVFNGLKRVIDFIEHFGFSESDLEYLKSIGYKDDFLSYLKDLKFTGSIRSMQE
                     GELCFGNEPLLRVEAPLIQAQLIETILLNIVNFHTLITTKASRIRQIASNDKLMEFGT
                     RRAQEIDAALWGARAAYIGGFDSTSNVRAGKLFGIPVSGTHAHAFVQTYGDEYVAFKK
                     YAERHKNCVFLVDTFHTLKSGVPNAIKVAKELGDKINFVGIRLDSGDIAYLSKEARRM
                     LDEAGFTETKIIASNDLDEETITSLKAQGAKVDSWGVGTKLITGYDQPALGAVYKLVA
                     IENEDGSYSDRIKLSNNAEKVTTPGKKNVYRIINKKTGKAEGDYITLENENPYDEQPL
                     KLFHPVHTYKMKFIKSFEAIDLHHNIYENGKLVYQMPTEDESREYLAQGLQSIWDENK
                     RFLNPQEYPVDLSKACWDNKHKRIFEVAEHVKEMEEDNE"
     gene            4699..5775
                     /locus_tag="RPH49_002087"
     CDS             4699..5775
                     /locus_tag="RPH49_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide synthase oxygenase"
                     /protein_id="HDY5125215.1"
                     /translation="MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHT
                     EEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKL
                     KPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPL
                     IYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYP
                     TAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVY
                     HSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYD
                     NTVKDPNFFYKKKESNANQCPFHH"
     gene            5795..6589
                     /locus_tag="RPH49_002088"
     CDS             5795..6589
                     /locus_tag="RPH49_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDY5125216.1"
                     /translation="MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNLFEVIKAVADD
                     DTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIRLDINFALYGNGSNTISDIKKVY
                     SIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHI
                     EDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIE
                     SRPLKTQLGMYRFFVQADSAITTDIKKVIAILETLDFKVEMIGAFN"
     gene            6661..6768
                     /locus_tag="RPH49_002089"
     CDS             6661..6768
                     /locus_tag="RPH49_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125217.1"
                     /translation="MVDFLLFVLFLHDAAVYVSLPLVQAIANVTFYFSF"
     gene            complement(6779..8341)
                     /locus_tag="RPH49_002090"
     CDS             complement(6779..8341)
                     /locus_tag="RPH49_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDY5125218.1"
                     /translation="MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFL
                     LTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQV
                     SSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
                     MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGT
                     LIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYL
                     PGGQTLIKQKLDELGNMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAI
                     FISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGE
                     QLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAP
                     AAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIV
                     LGIDINQPLPLK"
     gene            complement(8546..9643)
                     /locus_tag="RPH49_002091"
     CDS             complement(8546..9643)
                     /locus_tag="RPH49_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectate lyase"
                     /protein_id="HDY5125219.1"
                     /translation="MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYD
                     ICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMN
                     GVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSG
                     ERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHA
                     SRHNRYYENIHIRNNIFEDIQGYALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNA
                     ADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVHNYNNVKHKDVLIVGNTFNDSTQ
                     SIHLEDIDTVFLSPVEAGIQVTTINIDEIKK"
     gene            10015..10575
                     /locus_tag="RPH49_002092"
     CDS             10015..10575
                     /locus_tag="RPH49_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDY5125220.1"
                     /translation="MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNY
                     YQDHIFFLMDLHYLHDIHHPESKLFPPHNIVDTSGRELYGKVGKLYETIKAQPNVHFI
                     DKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVA
                     SFNQKGHEWALAHFKNSLGAEVEQHV"
     gene            10628..11557
                     /locus_tag="RPH49_002093"
     CDS             10628..11557
                     /locus_tag="RPH49_002093"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDY5125221.1"
                     /translation="MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVS
                     AETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIAN
                     FETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQ
                     QDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQ
                     VNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGE
                     AFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK"
     gene            complement(11752..11925)
                     /locus_tag="RPH49_002094"
     CDS             complement(11752..11925)
                     /locus_tag="RPH49_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125222.1"
                     /translation="MNVVAVNFKWSFELYMLKVENRAMNRLHNNIYNFNHNEKGRKKT
                     KIYTQHRKYFKKM"
     gene            11977..13356
                     /locus_tag="RPH49_002095"
     CDS             11977..13356
                     /locus_tag="RPH49_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDY5125223.1"
                     /translation="MNIIEQKFYDSKAFFNTQQTKDISFRKEQLKKLSKAIKSYESDI
                     LEALYTDLGKNKVEAYATEIGITLKSIKNARKELKNWTKTKNVDTPLYLFPTKSYIKK
                     EPYGTVLIIAPFNYPFQLVFEPLIGAIAAGNTAIIKPSELTPNVARVIKRLINETFDA
                     NYIEVIEGGIEETQTLIHLPFDYVFFTGSENVGKIVYQAASENLVPVTLEMGGKSPVI
                     VDETANIKVASERICFGKFTNAGQTCVAPDYILVHESVKDDLITALSKTLREFYGQNI
                     QQSPDYGRIVNLKHYHRLTSLLNSEQMNIVFGGHSDEDERYIEPTLLDHVTSDSAIMQ
                     EEIFGPILPILTYQSLDEAIAFIHQRPKPLSLYLFSEDENATQRVINELSFGGGAIND
                     TLMHLANPKLPFGGVGASGMGRYHGKYSFDTFTHEKSYIFKSTRLESGVHLPPYKGKF
                     KYIKAFFKN"
     gene            complement(13476..14504)
                     /locus_tag="RPH49_002096"
     CDS             complement(13476..14504)
                     /locus_tag="RPH49_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDY5125224.1"
                     /translation="MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLETGFELEASTYL
                     VRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFE
                     AVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAV
                     TDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAE
                     YNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQH
                     LELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERNKETGKITLCDNTRVA
                     SEGVCVIF"
     gene            14774..14911
                     /locus_tag="RPH49_002097"
     CDS             14774..14911
                     /locus_tag="RPH49_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125225.1"
                     /translation="MTSYEEETDYRNVPRELLDNNIPMGRGMIKWAAFIICTNLIKNL
                     I"
     gene            complement(14963..15343)
                     /gene="blaI"
                     /locus_tag="RPH49_002098"
     CDS             complement(14963..15343)
                     /gene="blaI"
                     /locus_tag="RPH49_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillinase repressor BlaI"
                     /protein_id="HDY5125226.1"
                     /translation="MANKQVEITMAEWDVMNIIWNKKSVSANEIVVEIQKNKEVSDKT
                     IRTLITRLYKKEIIKRYKYNNIYFYSSIIKEDDIKMKTAKTFLNKLYGGDMKSLVLNF
                     AKNEELNNKEIEELQDILNDISKK"
     gene            complement(15333..>16587)
                     /locus_tag="RPH49_002099"
     CDS             complement(15333..>16587)
                     /locus_tag="RPH49_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDY5125227.1"
                     /translation="SPITFWYGKYIILIPSLYFKSINDKKLKYIILHEYAHAKNRDTL
                     HLIIFHIFSIAMSYNPLIQIVKRKMIHDNEVEADRFVLNNINKNEFKSYAEAIMDSVL
                     KTPFFNKNILSHSFNGKKSLLKRRLINIKEANLKKQSKLILIFVCIFTFFIMIIQSQF
                     LMGQSLTDYNYKKPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIYNEKESRKRYS
                     PDSTYKIYLALFGLDRHIISDKNSRMLWNHNHYPFDSWNKDQDLNTAIQNSVNWYFER
                     ISNQISKNYTYDQLKQLNYGNKNLGSYKAYWLEDSLKISNLEQVIVLKNMMEQNNHFS
                     KNEKKQLSSSLLIRKNENYALYGKTGTGIVNGKYNNGWFVGYVITNHDKYYFSTHLSD
                     EKASGENAKLINEKILKEMGVLNGQ"
BASE COUNT         5547 a         2891 c         2364 g         5785 t
ORIGIN      
        1 tgtaagctga ctatatgtca gcttctgtgt tggggcccct gtcttcgact ggcactgctc
       61 cctcaggagt ctcgccatta atactacgta ttaacatgtt attttacttt taaatacttt
      121 aaaaaaataa gacactttgc ccaacttgca cataaatgta aaattcaata aaatgaattt
      181 tctgtgttgg gtcccttcgc ataatttaat aaataccact aaactaaatt aacgaggtgc
      241 cttatgtata aaaattataa catgacccaa cttaagccag gatacaattt acaaatagcg
      301 acaaattctc aatttgtttt atcctatgac ctatttcaaa acccgacaga tactagaact
      361 ttaattccat ttttaacaat gattcaaaat accttcggtt atttaccgga gtatattgta
      421 gctgatgcag gttatggtag tgagcaaaac tatatggcta ttatagatga ctttaataaa
      481 acgccactta ttacgtatgg catgtttatt aaagataaaa cgagaaagtt taaaagtgac
      541 atttttaaca ctcaaaatta gaaatatgac gaacttaatg atgaatttat atgtcctaat
      601 aacaaaagaa taggttttaa aagatatgca taccgtaatg atagatatgg ttttaaacgt
      661 gacttcaagc tatatgaatg cgatgactgt tcagcatgtt ctttgaggca acaatgcatg
      721 aaaccaaatt cgaaatccaa taagaaaatc atgaagaatt ataattggga atactttaaa
      781 gcccaaatta atcaaaagct ttctgaacca gaaacgaaaa aaatctatag tcaaagaaaa
      841 attgatgtag agcctgtttt tggatttatg aaggctattt tgggtttcac tcgaatgtca
      901 gttcgaggaa taaataaagt taaacgagag ctaggttttg tattaatggc acttaatata
      961 aggaaaatag cagctcaacg agctgtacat tataaaatac atatcaaaaa agctgatttc
     1021 tatcaaataa ttaatagaaa tcagcttttt tacattgcct aagaacttaa tgtcccaagc
     1081 cctttctcat acaatatgaa tctagcatct tgcatgtata aacaaatagg ctatccaaag
     1141 taaaattact caaactttga atagcctttc ctattcaaat agtctttatt taaattggat
     1201 tatgttattg gattttctta cctacaaaaa tgatttcttg atgtgatact tcaaccgtgc
     1261 catcattttg ctcctgaaac acgggttttt caatacgttt taccggcata tacccttgca
     1321 ttttcattcg tgacaaacaa tcagcaattg tttcgttctc atttactttg aatttcatgt
     1381 tctactacac tttccagttc ttctggttca taatctttaa gctttctacg acgaatgcct
     1441 ttagtccaga atccaccatg tatgtttcga ggttcatacg caatgataaa tgctttcgga
     1501 tctaaatttt ttatcgtatc catcaattta cgttcatatt ttcttggtgt taaaatttgc
     1561 atcaccatac gactaccatc tctaccaaac gcagcatagt gcgtaacgcc atatcctaaa
     1621 tttcgaagtt cattcggcaa atctaactca tattctgctg aagttacatt tacaactgta
     1681 taacctaatg ccagtttttc ttctattttc ataccaacaa tgatacctat tgaaaaacca
     1741 aatgcgtagg caataatatt ttgaatatgg tctaaattag acataaccaa acctaaacca
     1801 acgatataaa ctaatacttc taaaaaacta actgatgcag caatataacg ataacctttc
     1861 aacgttaaaa ttgttcgcat cgttaaaaac gttacataac aaacgttaat gataaatata
     1921 gttagtacca ttaaccatgg attttctgtt acgaatgaca taaggcgccc cactctcttt
     1981 caattacact ttaaatacca aactgcttca aactaacctt aatgaatgca tattaatata
     2041 atatagtacg aaaactctca taaataaata gcgaatttgt cataaataaa aatttattct
     2101 caaatgaaca tacttacttt agttcataca ctttcaattt atacactgaa gtagtctagc
     2161 tgaatgtggt ttaatgttat taattctaac tcatatttaa tttaagtcac acgttagaag
     2221 aaaaaattaa attaggattt tggccacgtg tatcttgtat atgcaagttc acgtttgtgt
     2281 gcatttcgta tataatgatt ttcaattact ttttgttctt ctggcgtaac tggcttacct
     2341 tctaaataat tatcaatcgc ctcataagtt acacctaatg catcttcatc tggaagctgt
     2401 ggtttatcat cttctaaatc agcagttggc gttttttcat ataattcctt tggcgcacca
     2461 agatacgcta ataattgacg accttgtcgt ttattcaaac caaatatagg tgcgatatct
     2521 gcagcaccat caccgtactt cgtataaaaa ccagttatat tttcagctga atgatctgtt
     2581 cctactacaa taccttgtcg gtttgaagca attgaaaatt gtactttcat acgttcacgc
     2641 gctttttcat ttcctttttg gaaatctgta agaacaatac cggcttcttt taatgattcc
     2701 acactttgat caactgcagg tttaatattt acagttacta tttcgtctgg ttcaatgaat
     2761 cgcaaagctt gctcaacttc atcagcatct ttttgaactc cataaggtaa tttaactgca
     2821 ataaacgtac aatcaatgcc ttcttcacgt aattcgttaa cagacatttg tactaatttt
     2881 ccaactaatg tagaatcttg tcctcctgaa atacctaaca ctaaagattt tataaatgaa
     2941 tgtgattgta cataattttt tataaattgc tttaattcca taatttcttc agcactatcg
     3001 atacgctttt tcactttcat ttcttgtaca ataacgtctt gtaatttact cattatcttc
     3061 ttccatctcc ttaacgtgtt ccgcaacttc aaaaatacgt ttatgtttat tatcccaaca
     3121 tgccttgctt aaatcgactg gatattcttg tggattcagg aaacgcttat tttcatccca
     3181 aatagattgt aatccttgtg ctaaatattc acgtgattca tcttctgttg gcatttgata
     3241 tactaattta ccattttcat aaatattatg atgcaaatca atggcttcga aagattttat
     3301 aaatttcatt ttataagtat gcactggatg gaataatttt aaaggttgtt catcgtatgg
     3361 attttcattt tccaaagtaa tataatcgcc ttctgcctta cctgttttct tgtttataat
     3421 gcgatataca tttttcttac ctggcgtcgt aaccttttca gcgttatttg ataatttaat
     3481 acgatcacta tatgaaccat cttcattttc aatagctaca agtttatata ctgcacctaa
     3541 tgctggttga tcatatcctg taatcagctt tgtaccaacg ccccaagaat ctacttttgc
     3601 accttgtgct ttcaaactcg taatcgtttc ttcatccaaa tcattagacg cgataatttt
     3661 agtttcagta aatcctgctt catcaagcat acgtcttgcc tctttagata aataagcgat
     3721 atctccagaa tctaatcgaa tacctacaaa gttaattttg tcacctaatt cttttgcaac
     3781 ttttattgca tttggcacgc cagattttaa agtatggaat gtatctacta ggaacacaca
     3841 atttttatgt ctttcagcat attttttgaa ggcaacatat tcgtctccat aagtttggac
     3901 aaatgcatgt gcatgtgtac cagacacagg tataccaaat aatttacccg ccctaacatt
     3961 acttgtagaa tcaaagcccc cgatgtaagc agctctagcg ccccacaatg ctgcatcaat
     4021 ttcttgcgca cgacgtgtac caaactccat taatttatca tttgatgcaa tttgacgaat
     4081 tctactagcc tttgttgtaa ttagtgtatg gaaatttaca atgtttaata aaattgtttc
     4141 tattaattgc gcttgaatca atggtgcttc tacgcgtaac aatggttcgt taccaaagca
     4201 taattcgcct tcttgcatcg aacggatgct acctgtgaat tttaaatctt ttaaatatga
     4261 taagaaatca tccttgtagc caatagactt taaatattcc aaatcagatt ctgaaaatcc
     4321 aaaatgttct ataaaatcaa tgacgcgttt taaaccatta aaaacagcat agccactatt
     4381 aaatggcatt tttctaaaat acaaatcaaa tacagccatt ttttcatgaa tattatcatt
     4441 ccaataactt tcagccatat ttatttgata taagtcatta tgtaacatta aactgtcgtc
     4501 ttctaattgg tacactcgta tctctccaat cgacctaaat attttcttac attttatcat
     4561 aattcatttt tttatataca taagagcccc ttaatttcca tacttttaat taaaatcaac
     4621 caacaattta atgacatata cataattttt aagagtattt taataatgta gactataata
     4681 taaagcgagg tgttgttaat gttatttaaa gaggctcaag ctttcataga aaacatgtat
     4741 aaagagtgtc attatgaaac gcaaattatc aataaacgtt tacatgacat tgaactagaa
     4801 ataaaagaaa ctgggacata tacacataca gaagaagaac ttatttatgg tgctaaaatg
     4861 gcttggcgta attcaaatcg ttgcattggt cgtttatttt gggattcgtt aaatgtcatt
     4921 gatgcaagag atgttactga cgaagcatcg ttcttatcat caattactta tcatattaca
     4981 caggctacaa atgaaggtaa attaaagccg tatattacta tatatgctcc aaaggatgga
     5041 cctaaaattt tcaacaatca attaattcgc tatgctggct atgacaattg tggtgatcct
     5101 gctgaaaaag aagttacacg cttagcaaat cacttaggtt ggaaaggaaa aggtactaat
     5161 tttgacgtgt taccactaat ttaccaatta cctaatgagt cagttaaatt ttacgaatat
     5221 cctacttcat taattaaaga agtacctatt gaacataatc attatccaaa attaagaaaa
     5281 ttgaacttaa aatggtatgc agtccctatc atttccaata tggacttaaa aatcggtggc
     5341 attgtatatc caactgcccc ctttaacggt tggtatatgg taactgaaat tggcgtacgt
     5401 aactttattg atgattaccg ttacaattta ctagaaaaag ttgcagatgc gtttgaattt
     5461 gatacactta aaaataattc atttaataaa gatcgagcac ttgttgaatt gaactatgct
     5521 gtgtatcatt cctttaaaaa agaaggcgta tcaattgtcg atcatttgac cgctgcaaag
     5581 caattcgaac tattcgaacg taatgaagca caacaaggtc gtcaagttac cggaaaatgg
     5641 tcttggctag cgccgccatt atctccaaca ttgacgtcaa attatcatca cggatatgac
     5701 aatacagtaa aagatccaaa ctttttctat aaaaagaaag aatcaaatgc taaccagtgc
     5761 cctttccatc attaagttag tagaggtgta gcatatgcaa ttatattatt taggccctaa
     5821 aggtacattt tcatatttgg cttgtcgtca gtatttttct gaaaatgaag caacttttca
     5881 accaaagtca aatttatttg aagtcatcaa ggcagttgca gatgatgaca catcgattgg
     5941 tgttgtccct attgaaaatt ctatagaagg aacaatcaac attgtggcag atgcacttgc
     6001 acagcaagat gtctttgcac acggtgaaat acgtctagat attaactttg cattatatgg
     6061 taatggttcg aacaccattt ctgatattaa aaaagtgtat tctattgcac cagcaatcag
     6121 tcaaacaaca aattacatac atcaacatca atttgactat gattatgtcg acagtacaat
     6181 tcaaagtttg actaaaattg aaaatggcgt tgcagcaatt gcacctttag gtagtggcga
     6241 agcttatggt tttacaccta ttgatacaca tattgaagac tatccacata acgtgacacg
     6301 ttttttagtt ataaaaaatc agcagcaatt tgatcaaaat gcgacatcat tgatgttttt
     6361 aattacacca atgcatgata aacctgggtt gttagcaagt gtgcttaata catttgcttt
     6421 gtttaatatt aatttatcct ggattgagtc tcgtccttta aaaacacaat taggtatgta
     6481 tcgatttttc gttcaggctg attctgcaat tacgacagat ataaagaaag tcattgctat
     6541 tttagaaacc ttagatttca aagtagaaat gattggtgct tttaattaaa ctatattttc
     6601 taggttctgc aatttaaata aaataaagag tcaaccaagg attaaaatag aaatccatcc
     6661 ttggttgact ttcttttgtt tgtattgttt ttacacgatg ctgcggtata cgtttcgtta
     6721 ccactcgttc aagcaattgc taatgtaacc ttttattttt cgttctaatc tgcaattact
     6781 atttcaatgg cagtggttga tttatatcaa tacctaaaac tataggcatt acataataca
     6841 caactaaaat aataattatt gcactgatta agtttaccca gaatcctact gatgccattt
     6901 gtttgataga tattttacct gaaccaaaga taattgcatt cggtggtgtc cctactggta
     6961 acatgtatgc acagttagcc gccatagctg caggtgccat aagtagtaat ggatgcacac
     7021 caaccgcaac agataacgtt gctaaaatcg gtaaaatcat cgttgcagtt gcggtattag
     7081 atgtcacttc agttaaaaat aggacaaaga tagttatgac gattacaata agaatcggac
     7141 tgacaccatt taatgatttc aactgttcgc ctaaccattt tgctaaacca ctttcagaaa
     7201 tacctttcgc taatgctaaa ccgccaccaa ataaaattaa gacaccccaa gggagctctt
     7261 ttgcaacttc ccagtcaatg atacgtcgat gtttttcagt atttttagct ggaataataa
     7321 ataataatat tgatataaaa atagcaatcg taccatctgc aacggatgac gtaacttccc
     7381 attttttcag aagaaactct cttgtaatcc ataataagct ggcaagtaca aagatagttt
     7441 gtactacctt ttcttcatac ttcatattgc caagctcgtc tagcttttgt ttaattaacg
     7501 tctgaccacc aggtaaatat ttcaaatcat gtctaaacgc aacatatctt aaatagagcc
     7561 aagtaatacc taacaaaaca atgaccgttg gaatccctac aatcatccat ttagcaaaac
     7621 taatttcatg tccaaaatgt tgcatgtatt gtccttttaa aataattagc ggcggggttc
     7681 cgattaatgt acccaagcca ccaatcgtac ctgcatagcc aattgctaaa actagagatt
     7741 tttcaaactt ttgaatactt gtttgattcg tattggcttc ttgtaaatca tgtgcttcct
     7801 taataattgc taaaccaatc ggaatcatga tcattacagc tgcagtgttc gatacaaaca
     7861 tagataagaa tcctgttgcc accatgaatc caagtaatat ttttgaagtg cttgcaccaa
     7921 ttaaattaat aatagtcaaa gctactctcg tatgtaaatt ccatctttcc attgcaattg
     7981 ccaaaataaa tccacctaaa aacaaaaaga taatatcatt accatattcg gatgatactt
     8041 gttctggtgt aagtatgtga cctaatggta ataacacaat tggtaataag ctcgttgctg
     8101 caataggaat tgcttcagta atccaccaag tcgcaatcca taaagtaatc gctaagacat
     8161 atacgccttt ccaaggtaag tcttgtggat gaaagaacaa taatgttaat aggaaaagta
     8221 atggacctaa tattagtcca ataagttgtc ccgcactaaa cggtttcttt ttctttgatt
     8281 ttgaaaagaa tgttaaatac cttttcgata tcattgattg atgttgattg aaataagcca
     8341 taaatttccc cctcatgatg attatgacaa gctacttcaa ctcactatat tagagtatag
     8401 aaagttgtct atcttgtatt atcattaccg tcaaaatacc ccttttatca gataattggg
     8461 tttattatag catatttata ccgttttatg aatgcgcttt caaaaattat ctactattct
     8521 taatcctaat gtcatgcgaa actttttact tttttatttc atctatattg attgtagtaa
     8581 cttgaatacc cgcttcaaca ggacttaaaa acactgtatc aatatcttct aaatgaattg
     8641 attgagtcga atcattgaat gtattcccaa cgattaatac atctttatgt ttaacattat
     8701 tataattatg tacatgtatc gcatctttag acattgatcc tttaaattca tttccaatga
     8761 tattcatatt tatgcctgct tgggaaccta agtcttttcc tgtcatcaca tctgcagcat
     8821 ttttaccatc tctaactcct aaatatctaa taccaccctc acagttaata aacttattat
     8881 taataatgaa agcatcttta tacttcaagg gagttaatgc ataaccttgt atatcttcaa
     8941 atatattatt tctaatatga atattctcat agtaacgatt atgtctactt gcatgtgagc
     9001 caatagcacg attccaactt cccatttcgg gcaattctga aggtccaaaa taacaatctt
     9061 cgataacgac atttttcgtt atcgtaccat ctgtcgttcc gaattttgga aaagcaccag
     9121 gtacttgaat gtctaattgt attgcttcag aataaaagcg ttcgccacta tagtctataa
     9181 atccttcaaa tgaacagctt ttaatataga gtccattaat cccgcaagca tcaattgcat
     9241 gaccactcac tacattctta atagtcacac ctattaattg aatatcttca gcatgcccaa
     9301 tgcacatagc tgtattgtta taaggatacg atacgccatt catatcaaac ttgccgcctt
     9361 taatatgaat atgactgtgt ccattataac cacgataaaa accaaagcga tgaccatttt
     9421 ttaataaagg accagaatga catcggcgta aaatagtttc attatccaac aaaagtgttg
     9481 tattgccata tatcgttaat ggtttgcaaa tatcatacgt ccctttcggt atataaactg
     9541 tcgttggttt acatcttcca cgatttaacg cacgttgtat tgctcgagta tctttagttt
     9601 tgtttatgcc tgttaaccca taatctttca tattgatata cataaatcgt catcctttgt
     9661 ctattttcta attactcata tattaaccaa ttattcaaat tataatcgtg ttaggttgat
     9721 ttaacagata gtcataaatc tcgtgatgcc atctattagc atttttatat tgaaaacatc
     9781 aacacttgat attagttcta agtttgtcac atttaatatt ctattacagc tattttaaag
     9841 ctatcgtaaa aacatcttat aatatttgtt gattgcgtga tttgctcttc caaaaaagtt
     9901 gattaatcta tatacttaat ctatatttat atattaacca ttagggttaa aaaatactct
     9961 agcatttatg aatagatggg agtttatttt attattatat aggagagatg ttgaatgaca
    10021 catcgcgcac tattagttgt tgactattca tatgacttta tcgcagacga cggcttacta
    10081 acatgcggta aacctggaca aaatattgaa gattttattg tttctcgtat caatgacttt
    10141 aattattatc aagaccatat attcttttta atggatttac attatttaca tgacattcat
    10201 catcctgaaa gtaaattatt cccaccacac aatatcgtag atacaagtgg tagagaatta
    10261 tacggtaaag taggtaaatt atacgaaaca attaaagcgc aacctaatgt acatttcatt
    10321 gataaaacgc gctatgattc gttctttggt accccgcttg atagtttatt gagagaaaga
    10381 agtattaatc aagtcgaaat cgttggtgta tgtaccgata tttgcgtgtt acatacagca
    10441 atttctgcat acaacttagg ttataaaatt tcagtacctg ctgagggagt ggcttcattt
    10501 aatcaaaaag ggcatgaatg ggcacttgca catttcaaaa actcattagg tgcagaggta
    10561 gaacaacacg tttaaatcgt gctaaaataa ttataaagaa tacaatatac aagggagata
    10621 tttgacaatg gctaaaacat atattttcgg acataagaat ccagacactg atgcaatttc
    10681 atctgcgatt attatggcag aatttgaaca acttagaggt aattcaggag ccaaagcata
    10741 ccgtttaggt gatgtgagtg cagaaactca attcgcgtta gatacattta atgtacctgc
    10801 tccggaatta ttaacggatg atttagatgg tcaagatgtt atcttagttg atcataacga
    10861 attccaacaa agttctgata cgattgcctc tgctacaatt aagcatgtaa ttgatcatca
    10921 cagaattgca aatttcgaaa ctgctggtcc tttatgttat cgtgctgaac cagttggttg
    10981 tacagctaca attttataca aaatgtttag agaacgtggc tttgaaatta aacctgaaat
    11041 tgccggttta atgttatcag caattatctc agatagctta cttttcaaat caccaacatg
    11101 tacacaacaa gatgttaaag cagctgaaga attaaaagat attgctaaag ttgatattca
    11161 aaagtacggc ttagatatgt taaaagcagg tgcttcaaca actgataaat cagttgaatt
    11221 cttattaaac atggatgcta aatcatttac tatgggtgac tatgtgactc gtattgcaca
    11281 agttaatgct gttgaccttg acgaagtgtt aaatcgtaaa gaagatttag aaaaagaaat
    11341 gttagctgta agtgcacaag aaaaatatga cttatttgta cttgttgtta ctgacatcat
    11401 taatagtgat tctaaaattt tagttgtagg tgctgaaaaa gataaagtcg gcgaagcatt
    11461 caatgttcaa ttagaagatg acatggcctt cttatctggt gttgtttctc gaaaaaaaca
    11521 aatcgtacct caaatcactg aagcattaac aaaataatac tatattactg tctaatcata
    11581 gacatgttgt atttaactaa cagttcatta aagtagaatt tatttcactt tcaatgaact
    11641 gttttttatt tacgtttgac taatttacaa ccccttttca atagtagttt tcattccttt
    11701 agctacccta acccacagat tagtgatttc tatacaattc cccttttgtc tttacatttt
    11761 cttaaaatat ttgcgatgtt gagtataaat ttttgttttc ttcctacctt tttcgttatg
    11821 attaaagtta taaatattat tatgtaaacg attcatcgct ctattttcaa ctttcaacat
    11881 atataattcg aaagaccatt taaaattaac ggccacaaca ttcaaatcaa ttaatcactt
    11941 tttccaaaat aatcatataa ggaggttctt ttcattatga atattattga gcaaaaattt
    12001 tatgacagta aagctttttt caatacacaa caaactaaag atattagttt tagaaaagag
    12061 caattaaaga agttaagcaa agctattaaa tcatacgaga gcgatatttt agaagcacta
    12121 tatacagatt taggaaaaaa taaagtcgaa gcttatgcta ctgaaattgg cataactttg
    12181 aaaagtatca aaaatgcccg taaggaactt aaaaactgga ctaaaacaaa aaatgtagac
    12241 acacctttat atttatttcc aacaaaaagc tatatcaaaa aagaacctta tggaacagtt
    12301 ttgatcattg caccatttaa ctatcctttt caactagtgt tcgaaccttt aatcggtgct
    12361 attgcagcag gtaatacggc aattattaaa ccatctgagt tgacaccaaa tgttgcacga
    12421 gtgattaaac gattaatcaa tgaaacattt gatgcaaatt acattgaagt tattgaggga
    12481 ggaattgaag aaacgcaaac gttaattcac ttaccttttg actatgtctt ctttacagga
    12541 agtgaaaatg taggcaaaat cgtttatcaa gctgccagcg aaaatttagt tcctgtgaca
    12601 ttagaaatgg gcggtaaatc tccagtcatc gttgatgaaa cagcgaatat taaagttgct
    12661 agtgagcgca tttgttttgg gaaattcact aatgccggcc aaacatgtgt tgcaccagat
    12721 tacattttag tacacgaatc tgtaaaagat gatttaatca cagccctatc aaaaacgttg
    12781 cgtgaatttt atggtcaaaa tatacaacaa agtccagatt atggccgcat tgtaaacctt
    12841 aaacattatc atcgtctgac ttcattactt aacagtgaac aaatgaatat tgtatttggt
    12901 ggtcatagtg atgaggatga acgttatata gaaccaacat tgttagatca cgttacaagt
    12961 gattcagcaa ttatgcaaga agaaattttt ggtcctatct taccgatttt aacgtatcag
    13021 tcattggatg aagcaatagc ctttattcac caaagaccaa aacctttgag tttatattta
    13081 tttagcgaag atgaaaatgc tacacaacgt gtaataaacg agctatcatt tggcggcggc
    13141 gctattaatg atacattgat gcacctagcg aatcctaaat taccatttgg tggtgttggc
    13201 gcctcaggta tgggacgcta tcatggtaaa tattcattcg acacttttac acatgaaaaa
    13261 agctacattt tcaaatctac acgattagaa tcaggtgtcc atttaccacc atataaaggt
    13321 aaatttaaat acatcaaagc tttctttaaa aattaatttt tgagccaaaa ataaaccatg
    13381 cttccataat ttgatgttct tgaaaacaat aaatttcaag gtatacataa attttttgga
    13441 aacatggttt tctttttatc atgattaatt aaagattaaa atatgacaca tacaccttca
    13501 gatgctacac gagtgttatc acatagcgta attttacctg tttctttatt tctttcgaaa
    13561 acagttacaa ctgaatctcc ttgctcatga gcacaaacta aaaggtcatc tgatgaggca
    13621 atattaaaat ctcttgggaa ttgaccacca ctttcagtaa ttgttactag ttctaagtgt
    13681 tgaccattat caagaacttt aaaaattgca atgctatcat gccctctatt agatacatat
    13741 aagaattgtt gatcatgaga taaacgcact gctgcaagtt tagtatctcc atcaaagttt
    13801 tcaggaattg ttaaatgacg ctcgagctct tcaaatttac cgtcattata ttctgcaaca
    13861 ctcacagtat ttgataattc gtgtacgaca taagcaaatt ttccattatc atgaaattca
    13921 atatgtcttg tcccatcact atctttaaat aaagattctt tataaaattc aaacccgttg
    13981 tcatcaaatt tataagtaac gatacgatca gcacctaaat ctgttactgc aacgtactta
    14041 ccatctggag tttgattaat ataatgtgcg tgtggatgat cttgtctttc atgtgtacct
    14101 gttggaaaat catgtgcaag ttcttgaatt agacgtataa tttcacctgt gtgcgtattt
    14161 aattcataca tacgtatgat gccagcacca tataccgctt caaataaata tcgtttatct
    14221 tctgaaatcg atacataaca acctgtacca gcttttgaag acaaacattt atttaataaa
    14281 tgcaattcac cattgtcatc aattttcaaa ctcgcaacac cgcattgttc tccttctttg
    14341 ttgattccat ataaaacttc gttattacgc accaaatatg tagacgcttc taattcaaat
    14401 cctgtttcta ataaatcaat acgtgactga ttttcgttta attcaaaacg ataaatccct
    14461 ttaccattct ttttagtgta agaaccaata tatccatttg tcattacttt tacccctcca
    14521 tgtcagtctt attttcattt tattaaattt tagctagaat taacaatcat ttatcatttc
    14581 cttaacgcta aaactgttta actactttaa aagaactatt tgctgtgata tgtcattatt
    14641 cgattttaat taatccctct tttttactta cacgagcatt aattattaac gcgtttatgc
    14701 ttccacaaaa tttttgttgc aaaatagaac acatgttcgt ataatgtaat tatcagattg
    14761 gggtgaatta aggatgacaa gttatgaaga agaaactgat tatcgtaacg ttccaagaga
    14821 attactagat aacaatatac ctatgggaag aggcatgatt aaatgggctg catttattat
    14881 atgtactaat ctcataaaaa atctaattta atagggttca aacataattt atatatgtat
    14941 tatgtttgaa ccctatatct atttattttt tactaatatc atttaaaatg tcttgcaatt
    15001 cttcaatttc tttgttattt aattcttcat ttttcgcaaa attaagcact aaacttttca
    15061 tatcccctcc atacaattta ttaagaaagg ttttagcagt tttcatttta atatcatctt
    15121 ctttaataat tgatgagtaa aaataaatat tattatattt atatcgtttt ataatctctt
    15181 ttttatatag tcttgtaatt aatgttctaa tcgtcttatc gctaacttct ttattttttt
    15241 gaatctcaac tacaatttca ttagctgata ctgatttttt attccatatt atattcataa
    15301 catcccattc agccatagtt atttcaactt gcttattggc catttaaaac acccatttct
    15361 tttaatattt tttcatttat taatttagca ttttcaccag aggctttttc atctgataaa
    15421 tgtgtagaaa aataatactt atcatgattt gtaattacgt aacctacaaa ccacccatta
    15481 ttgtacttcc cgtttactat acctgtacct gttttcccat acaatgcata attttcattt
    15541 tttctaatca ataacgaaga agataattgt ttcttttcat ttttactaaa atggttattt
    15601 tgttccatca tatttttcaa aactattact tgttcaagat tagatatttt caaactatct
    15661 tccaaccagt aggctttata acttcccaaa tttttattac cataatttaa ttgcttgagt
    15721 tgatcataag tatagttctt tgatatttga ttactaatac gttcgaagta ccaattaaca
    15781 gagttttgta ttgccgtatt taaatcttga tccttattcc aagaatcgaa aggataatga
    15841 ttatgattcc ataacatacg tgaattttta tcacttataa tatgacggtc aagtccaaac
    15901 agtgctaaat aaattttgta tgttgaatca ggagaatatc tttttctact ttctttttca
    15961 ttataaatat agtatttgtc tttcttcatg ctgtacataa cgaaagatcc actatttgaa
    16021 ccaaaatttt tactttcatc taaaatttgg taatcgcttt gtaagggctt tttataatta
    16081 taatcagtta aggattgccc cattaaaaac tggctttgaa ttatcatgat aaaaaaagta
    16141 aaaatacaaa caaaaattag aattaatttt gactgctttt tcaaattggc ttcttttata
    16201 ttaattaatc ttcttttgag taatgatttt ttaccattaa atgaatggct taatatattt
    16261 ttgttgaaaa atggggtttt taatacggaa tccataatag cttccgcata agacttaaat
    16321 tcatttttgt taatattatt aaggacaaat ctatcggctt ctacttcatt gtcatgaatc
    16381 atctttcttt ttacaatttg tattagtgga ttataactca tagcaataga aaaaatatga
    16441 aagataatta aatgcaaagt atctctgttt ttagcatgag catactcgtg caatattata
    16501 tattttagtt ttttgtcatt tatactttta aaatataaac tgggaatcaa aataatatat
    16561 tttccatacc aaaaagttat tggagaa
//
LOCUS       DAPSKH010000057        16405 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPSKH010000057 DAPSKH010000000
VERSION     DAPSKH010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 16405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16405
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.057"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..419
                     /locus_tag="RPH49_002100"
     CDS             <1..419
                     /locus_tag="RPH49_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000284214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HDY5125228.1"
                     /translation="GAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQ
                     KMIFIPHKGQKNVEPQIGVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAI
                     VEYRNQQGAFQEIDDLKKVKDFGSKTFDKLKSYFTI"
     gene            511..972
                     /locus_tag="RPH49_002101"
     CDS             511..972
                     /locus_tag="RPH49_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDY5125229.1"
                     /translation="MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYN
                     GSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCT
                     KSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG"
     gene            977..3178
                     /locus_tag="RPH49_002102"
     CDS             977..3178
                     /locus_tag="RPH49_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDY5125230.1"
                     /translation="MLYVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPIS
                     LFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEI
                     YPFFLTNKKNFDLKKIESRNCIVKGQFKVNDNKFVTLKLQSIVVQSCLESNRSNLIEK
                     HKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAI
                     VFLIYQPLKRLNLPLFVIKGITIIVLALFAQYTNYAPSAVRAIIMTTLVLLITKQIKI
                     KGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFI
                     AQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYL
                     VDLSFNFHDWLLDLFTRIKQSHFSVPKFNDLIFIIFIISVYYIFWLLAKRKYILVTVW
                     TIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYS
                     ISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTL
                     MLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKK
                     VLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKN
                     NMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL"
     gene            3235..4209
                     /gene="holA"
                     /locus_tag="RPH49_002103"
     CDS             3235..4209
                     /gene="holA"
                     /locus_tag="RPH49_002103"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDY5125231.1"
                     /translation="MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYE
                     TEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENL
                     IVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALD
                     LFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRK
                     KEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYR
                     VKLALGQVRHYQLDELLNIIDACAETDYKLKSSYMDKQLILELFILSL"
     gene            complement(4254..4505)
                     /locus_tag="RPH49_002104"
     CDS             complement(4254..4505)
                     /locus_tag="RPH49_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDY5125232.1"
                     /translation="MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNAD
                     NKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK"
     gene            4851..6674
                     /gene="lepA"
                     /locus_tag="RPH49_002105"
     CDS             4851..6674
                     /gene="lepA"
                     /locus_tag="RPH49_002105"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDY5125233.1"
                     /translation="MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRD
                     MQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMI
                     GLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISS
                     IRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDD
                     SRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLE
                     FEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVT
                     VDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVN
                     IVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFI
                     VHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGG
                     DISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE"
     gene            7182..8306
                     /locus_tag="RPH49_002106"
     CDS             7182..8306
                     /locus_tag="RPH49_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDY5125234.1"
                     /translation="MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMS
                     TAKYRNLMTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQL
                     LEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPK
                     QTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLL
                     MSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPV
                     KHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFQKKFDQSIESVFG
                     QTINNLKEKELILEKNDAIALTKRGKVIGNEVFEAFLIND"
     gene            8407..9384
                     /gene="hrcA"
                     /locus_tag="RPH49_002107"
     CDS             8407..9384
                     /gene="hrcA"
                     /locus_tag="RPH49_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor HrcA"
                     /protein_id="HDY5125235.1"
                     /translation="MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRN
                     EMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQY
                     DVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
                     HVHLASDIPFNNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINQLLNTMN
                     NHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKI
                     GNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW"
     gene            9416..10042
                     /gene="grpE"
                     /locus_tag="RPH49_002108"
     CDS             9416..10042
                     /gene="grpE"
                     /locus_tag="RPH49_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDY5125236.1"
                     /translation="MTNKDESVEKNTESTVEETNVKQNIDDSVEQAEESKGHLQDEAI
                     EETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQ
                     AQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEG
                     EAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ"
     gene            10111..11943
                     /gene="dnaK"
                     /locus_tag="RPH49_002109"
     CDS             10111..11943
                     /gene="dnaK"
                     /locus_tag="RPH49_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDY5125237.1"
                     /translation="MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKN
                     GETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAE
                     SYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDK
                     DEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKEN
                     GVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFE
                     ELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKG
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSK
                     SQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDK
                     NGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNE
                     ADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQ
                     ELSAKVYEQAAQQQQQAQSANGGQNNDSTVEDAEFKEVKDDDKK"
     gene            12079..13218
                     /gene="dnaJ"
                     /locus_tag="RPH49_002110"
     CDS             12079..13218
                     /gene="dnaJ"
                     /locus_tag="RPH49_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDY5125238.1"
                     /translation="MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADE
                     KFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFS
                     SFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPG
                     TSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKT
                     VKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKL
                     NVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDI
                     KVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE"
     gene            13222..14160
                     /gene="prmA"
                     /locus_tag="RPH49_002111"
     CDS             13222..14160
                     /gene="prmA"
                     /locus_tag="RPH49_002111"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDY5125239.1"
                     /translation="MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPED
                     KYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNVQFSEQI
                     IAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTT
                     SMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRR
                     NHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIK
                     EKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE"
     gene            14162..14914
                     /locus_tag="RPH49_002112"
     CDS             14162..14914
                     /locus_tag="RPH49_002112"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDY5125240.1"
                     /translation="MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFN
                     DQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELG
                     ASSFIAVSMERSIVKLNEAKVAKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICD
                     TIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNT
                     STVVGLGPRILRAETAPLYALSAISYENELMG"
     gene            14921..16267
                     /gene="mtaB"
                     /locus_tag="RPH49_002113"
     CDS             14921..16267
                     /gene="mtaB"
                     /locus_tag="RPH49_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-
                     methylthiotransferase MtaB"
                     /protein_id="HDY5125241.1"
                     /translation="MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVI
                     NTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDR
                     HKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFC
                     IIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDL
                     ETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTM
                     DRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPR
                     IGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYASKFDQDVLEVIPEEQGDTEGTL
                     VGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV"
BASE COUNT         6117 a         2196 c         3035 g         5057 t
ORIGIN      
        1 aaggtgctgt taaacatcct aatgtttata aaatgacatc taaggataga gtagttgatt
       61 tacttgataa agcacaatta ttggaggatg cagatgtaag tcaaattaat ttgtctgaaa
      121 aattaacaga tcaaaaaatg attttcatac ctcataaagg acaaaagaat gttgaaccac
      181 aaattggagt aaacagtgtg catgtaaaaa atgggaacac aaataatact aaagtaaatt
      241 taaataccgc atctgtatca gaattgatgt ctgttcctgg agtagggcaa gctaaagcta
      301 atgcaattgt tgaatatcgc aaccaacaag gtgcatttca agaaattgac gatttgaaaa
      361 aagtaaaaga ttttggaagt aaaacttttg ataaactgaa atcttatttc acgatataat
      421 ggattatttt aattgcaaat tttatttttt gtgattaatc ttatattatt agaaaatgtt
      481 actaaatttt aagtatggaa ggtgaacatc ttggaaagaa tcaaatggga agaatatttt
      541 atggcacaaa gtcatttgct agcattacgt tcaacttgtc aaagattatc tgtaggtgca
      601 acgattgtta aggataatcg tattattgct ggtggttata atggctctgt agctggcgag
      661 gtgcattgta tagatgaagg atgtttaatt gaagatggac attgtatcag aacgatacat
      721 gcagaaatga atgctttatt acaatgtgca aaacaaggtg tatctactga aggtgcaaca
      781 atctatgtta ctcattttcc atgcctaaat tgtacaaagt caattattca agcaggtata
      841 aagcgtatct actatgcaga agattatcat aaccatgaat atgcaactaa attactcaaa
      901 caatctggta ttgaatttaa aaaaattcca ttttcaccag aatatgttgc taaatatctg
      961 actaaaggtt aatgttttgc tgtatgtcgc gttatcaatg attgtaggag tgctttggaa
     1021 ttctagcaaa gtgctctcta catttctttt cattttactt ttgtatatta cttatcgtaa
     1081 aaataaaatc gtttatgccc ctatttctct ctttttaatc attttctcct catggtattt
     1141 acattattca caacaagcaa tatttaatta tatcaattat attgaacgta attctcagtt
     1201 taatgagcgt gctcaagtaa tccaaattca acgtcaaggt agtgacacat ataaaggtag
     1261 gttgagttta aaaaatgaaa tatatccttt ctttttaaca aataaaaaga attttgattt
     1321 aaagaaaatt gaaagtcgta attgtattgt taaaggacaa ttcaaagtta atgacaataa
     1381 gtttgtaact cttaaattac aaagtatagt tgtacaaagc tgcctagaat cgaaccggtc
     1441 taatttaatt gagaaacata aacagtttat aatgaatcga atttatgatt cgggtattaa
     1501 gtttccggat cgtattatgg cattgattac tggtgacgta aaagaaatta atgagcaatt
     1561 taaggaacgt gttaaagaga taggtatata tcatttgctg gcagttagtg gctcgcatat
     1621 agctgcaatt gtattcttaa tttaccaacc tttaaaacga ttaaatttac ctttatttgt
     1681 cattaaagga attacaatca ttgtattagc tttatttgct caatacacaa attatgcacc
     1741 tagtgctgta agagctataa taatgacaac tcttgtactg cttattacta agcaaattaa
     1801 aataaagggt attcagctat tagcatttgc atttataatt atgtttattt taaatccact
     1861 agttgtttat gatattggat ttcaattttc attcatcatt tcatttttta ttatgctact
     1921 ttttcctttt ttacagcaat tgtcaaagtt acaatcatta ttcataatta cgtttattgc
     1981 acaattagct tcatttatcg ttgccattcc aaactttcat caacttcaat gggtgggatt
     2041 tttatctaat ttgatttttg taccgtacta ttcgattata ttgtttccgc tatctatttt
     2101 attctttatt acaagtcatt ttattgtggg attaacgccg ctaaattact tggttgacct
     2161 aagttttaat tttcatgact ggttactaga cctattcaca agaatcaagc aatcacattt
     2221 ttctgttccc aagtttaatg atttgatatt tataatattt ataatttctg tttattacat
     2281 attttggtta ttggctaaac gtaaatatat attggttacg gtttggacta taattattct
     2341 gacattatta ataacgtttc caacaaattc acatcacaaa attacaatgt taaatgtggg
     2401 gcagggagac agtattttat atgaaggtgg taagaaccaa aatgtcttga ttgatacagg
     2461 tgggaaagtg attgatgata ctaaacaacc tagttattca atttctaaat atcatatttt
     2521 accaacgcta aatgaaagag ggataaatga attagagtat ctaattttaa cacatccaca
     2581 caatgaccat attggtgaag tggaatatat tattagtcat attaaaatta aacatatagt
     2641 gatatacaat aagggatata gtagtaatac attgatgtta ttatcgaaat taagccataa
     2701 gtataacatt aaacttatgg atgtaagaca agttagtagt tttaaacttg gagatagtag
     2761 ttttctattt tttgatagtt ttattccaaa tagccgagat aaaaatgaat attctattat
     2821 tactatgatt acatatcaaa ataaaaaagt tttattaatg ggcgatgcta gtaaaaataa
     2881 tgaatcttta ctactaaaaa aatataactt gccggagatt gatattttaa aagtaggaca
     2941 tcatgggagc aagacaagta gttctaaaga atttatagag atgattaagc ctaaaataag
     3001 tttgatttct tctgggaaga acaatatgta tcatcttcct aatatagaag ttgttaaacg
     3061 attgcaaagg attcgcagtc gcatttacaa tagtcaacaa aacggtcaag ttacaattga
     3121 cttagatgat aatttaaaag ttgattcaaa ctcttatgga aatgcaagtg gtttatagat
     3181 acagaaacat gatataatct attgatgtgt caaacgaatg aaagggtgta atgaatgagc
     3241 gacaatattg tagctattta tggagatgtg cctgaattgg ttgaaaaaca aagtgcagaa
     3301 atcatatcac aatttttgaa aagtgataga gatgacttta actttgtgaa atataattta
     3361 tacgaaacag agattgcacc aattgttgaa gaaacattaa cattgccttt cttttcagat
     3421 aaaaaagcaa ttttggttaa aaatgcatat atatttacag gtgaaaaagc gccaaaagat
     3481 atggctcata atgtagatca attaatagaa tttattgaaa aatatgatgg cgaaaatttg
     3541 attgtctttg agatatatca aaataaactt gatgaaagaa aaaagttaac taaaactcta
     3601 aaaaagcatg caaggcttaa aaaaatagag caaatgtctg aagaagaaat aaaaaaatgg
     3661 attcaaagta aattaaatga gaatttcaaa gatatcaaaa gagatgcatt agatttattt
     3721 attgagttga caggtattaa ctttaatatt gtctcacaag agatagaaaa gttgatttta
     3781 tttttaggcg atagaccaac aattaataag caggatgtta accaaattat taatagaagt
     3841 ttagaacaaa atgtattttt actgactgaa tacattcaga aaagaaagaa agaacaagca
     3901 attcatttag taaaagattt aataactatg aaagaagaac ctattaaatt acttgcacta
     3961 attacaagta attaccgatt attttatcaa tgtaagattt tgagtcaaaa aggatatagt
     4021 ggacagcaaa ttgctaaaac aataggcgta catccataca gagtaaaatt agcgttagga
     4081 caagtaagac attatcaact tgatgaatta ttgaatatta tagatgcttg tgcggaaact
     4141 gattataaac ttaaatcatc atatatggat aaacagttaa tactggaatt attcattcta
     4201 tctttataaa aaataaaagt tcaagcatgc gcttgaactt ttatttaaaa agattattta
     4261 tttgcagtca ttaattgtga tttaatacgg tcagctttgt ttgaatgtat taaattactt
     4321 tgagcagctt tgtctactaa cttaactgct aagcttacta attcattttt attatcagcg
     4381 ttatttgaaa cagctgtttt agcgttttta actgctgtac gcattgcact cttttgtgaa
     4441 atgttgcgtg cttcagcttt ttcagttgtt tttacgcgtt taattgcaga tttgatattt
     4501 gccatttctg tcacctccta aaagtgagtt catcttatca aaattttatt tgattacaac
     4561 aagaaatatt ttaacaaaag tctaaccgtt gtgcaatcat ttatttgatg gggttagctt
     4621 aaaattttgc agatttaata aattgtgttg gaaacacaat caatacgttt tataattata
     4681 agtacgtaat taacatatta acatatcgca agtatgtatt taaataaaga ttgttataat
     4741 ttcaaagttc atccaagatt atggcgtttg catttaccta ttaaaaacgt tattatatca
     4801 aagatgcgaa agataatacg ggtttatttt atgaaagtga gaaggataaa atggataatg
     4861 agcaacgctt aaaaagaaga gagaatataa ggaatttctc gattatagca catattgacc
     4921 acggaaaatc tacattggct gatagaattt tagaaaatac caaatcagtt gaaacaagag
     4981 atatgcaaga tcagttacta gattcaatgg atttagaaag agaacgtggt attacaatca
     5041 aattaaacgc agtacgttta aagtacgaag ctaaagatgg aaatacttat acattccatt
     5101 taatcgatac gcctggacac gtcgatttta catatgaagt gtcacgttct ttggcagctt
     5161 gtgagggtgc gattttagta gtagatgcgg ctcaaggtat cgaagcacaa acattagcaa
     5221 atgtttattt ggcattagat aatgagttag agttattgcc tgttattaac aaaattgatt
     5281 tacctgctgc agaacctgaa cgcgtgaaac aagaaattga ggatatgata ggtttagacc
     5341 aagacgatgt tgttttagca agtgctaaat ctaacattgg aattgaagag atactagaga
     5401 aaatagttga agttgtgcca gctccagatg gtgacccaga agcaccacta aaagcgttaa
     5461 tatttgattc tgagtatgat ccatatagag gggtaatttc atcgataaga attgtagacg
     5521 gtgttgttaa agccggggat aaaattcgaa tgatggccac tggtaaagag ttcgaagtaa
     5581 cagaagttgg aattaataca cctaagcagc ttccagttga tgaattaaca gttggtgatg
     5641 ttggttatat tattgcaagt attaaaaatg ttgatgattc tagggttggt gacacaatca
     5701 cattagctag tagacctgca tcagaaccat tgcaaggtta taagaaaatg aatccaatgg
     5761 tatattgcgg actgttccca atagataaca aaaattataa tgatttaaga gaagcattag
     5821 aaaaattaca attgaatgat gcatcattag aatttgagcc tgaatcatca caagcattag
     5881 gttttggtta tagaactggt ttcttaggta tgttacacat ggaaataatt caagaaagaa
     5941 ttgaaagaga atttggtatt gaattaattg caaccgcacc atctgtaatt tatcaatgta
     6001 ttttaaggga cggttcagaa gtgacggttg ataacccagc acaaatgcca gatcgtgata
     6061 aaattgataa aatatttgag ccatatgttc gagcaactat gatggttcca aatgactatg
     6121 tcggtgcagt aatggaatta tgtcaacgta aacgtggaca atttataaat atggactatt
     6181 tagatgatat tcgtgtaaat attgtttatg aattaccttt agctgaagtt gtatttgatt
     6241 tcttcgatca acttaaatct aatactaaag gatatgcatc atttgattat gaattcatcg
     6301 aaaataaaga aagtaattta gtcaagatgg atattttatt aaatggtgat aaagtggatg
     6361 cgctaagctt catagttcat agagattttg cgtatgaacg tggtaaagca ttagttgaaa
     6421 aacttaaaac gttaattcca agacagcaat ttgaagtacc tgtacaggct gcaataggac
     6481 aaaaaattgt agcgcgtaca aatattaaat caatgggtaa aaacgtttta gctaaatgtt
     6541 atggcggtga cataagccgt aaacgtaaat tacttgaaaa acaaaaagca ggtaaagcta
     6601 agatgaaagc agttggtaat gttgaaattc cacaggatgc tttcttggct gtgttgaaaa
     6661 tggatgacga ataagttttt aaaaaatcta ttaacaattt acaatgaata aagtttaata
     6721 actaaaaaga gggagcctag gataaattaa cgtcctgggc tttacaatgt tatattggca
     6781 gccatcgaca gagttaaaat gagcttataa caatggggcc ccaacataga agctgacgaa
     6841 aagtcagctt acaataatgt gcaagttggg gtgggacgac gaaataaatt ttgtgaaaat
     6901 atcatttctg tcccactccc ttatgcatga gtttaactca tgtaattcta tttttaagta
     6961 catattacct ctggctaatg tgtaagagcc actacataat aaatcattag tggttcttta
     7021 ttatttctat ctcactccct cttaacattt ataaatatta aaatgaatcg atatattaga
     7081 caatcattga ttaaacgtta aagttaaaag taagaataat agcagatagt ccaacaggat
     7141 gtagccgatt ggataaacag tctgagaagc ggggcattaa aatgacggta caaagtgcat
     7201 atatacatat tccattttgt gtaagaatat gtacatattg tgatttcaat aaatatttta
     7261 tacagaatca acctgtagat gagtacttag atgcactaat aacagaaatg tctacagcca
     7321 aatataggaa cttaatgacc atgtatgtag gtggtggcac accaacggcc ctttctatta
     7381 atcagttgga aagattactt aaagcaatac gtgatacgtt tacaatcaca ggcgagtata
     7441 catttgaagc caatcctgat gagttaacta aagagaaagt ccaactatta gagaaatatg
     7501 gagtaaacag aatttcaatg ggcgttcaaa cattcaagcc ggagttattg tctgttttag
     7561 gtagaacgca caatactgaa gatatttaca cttcggtgtt aaatgctaaa aacgcaggta
     7621 ttaaatcaat cagtttagat ttaatgtatc atttaccgaa acagacgatt gaagattttg
     7681 aacaaagttt agatctagct ttagatatgg atattcaaca tatttcgagt tacggcttaa
     7741 tacttgaacc taaaacccaa ttttataata tgtatagaaa agggttgctc aaacttccta
     7801 atgaggattt aggtgctgac atgtatcagt tgctgatgtc taagatagaa caatctcctt
     7861 tccatcaata cgaaatatct aattttgcat tagatggcca tgaatcagaa cataataagg
     7921 tttactggtt taatgaggaa tattatggat ttggagcagg tgcaagtggt tatgtagatg
     7981 gtgtgcgtta tacgaatatc aatccagtga aacattatat caaagctata aataaagaaa
     8041 gtaaagcaat tttagtatca aataaacctt ctttgactga gagaatggaa gaagaaatgt
     8101 ttcttgggtt gcgtttaaat gaaggtgtga gtagtagtag gttccaaaag aagtttgacc
     8161 aatctattga aagtgtcttt ggtcaaacaa taaataattt aaaagagaag gaattaattt
     8221 tagaaaagaa cgatgcgatt gcactaacaa agcgagggaa agtcatcggt aatgaggttt
     8281 ttgaagcttt cctaataaat gattaaaaaa aattgaaatt tcgagtcttt aacattgact
     8341 tactttgacc aatttgataa attataatta gcacttgaga taagtgagtg ctaatgaggt
     8401 gaaaacatga ttacagatag gcaattgagt atattaaacg caattgttga ggattatgtt
     8461 gattttggac aacccgttgg ttctaaaaca ctaattgagc gacataactt gaatgttagt
     8521 cctgctacaa ttagaaatga gatgaaacag cttgaagatt taaactatat cgaaaagaca
     8581 catagttctt cagggcgttc gccatcacaa ttaggtttta ggtattatgt caatcgttta
     8641 cttgaacaaa catctcatca aaaaacaaat aaattaagac gattaaatca attgttagtt
     8701 gagaatcaat atgatgtatc atcagcattg acatattttg cagatgaatt atcaaatata
     8761 tctcaatata caactttagt tgttcatcct aatcataaac aagatattat caataatgta
     8821 cacttgattc gtgctaatcc taatttagtt ataatggtta tcgtattttc atcaggtcat
     8881 gtagagcatg tacatcttgc ttcagacata ccgtttaata acgacaaact aaatacaata
     8941 tcaaattttg ttacaaacaa actaactgag tttaatcaga atttacaaga tgatattgtc
     9001 tcttttgttc aatcagagca ggaagaaata tttatcaatc aattgttaaa tacgatgaat
     9061 aatcatattt ctaatcaaag taatagcatt tatatgggtg gaaaggttaa acttattgat
     9121 gcattgaatg aaagtaatgt atcttcaatt cagcccattc tacaatatat agaatcaaat
     9181 agaattgcag aattattaca agatatatct tcaccaaata ttaatgtaaa aattggtaac
     9241 gaaattgatg acagcttaag tgatatttca attgtaacaa gtcaatatca ttttgatgaa
     9301 acgttaaaag gtcaaatcgc tgtgattgga cctacagcta tgcattatca aaatgtcatt
     9361 caattattaa atagaatttg gtaatgatgg attagaaagt attggaggac agaaaatgac
     9421 aaataaagac gaatcagttg aaaaaaacac tgaatcaaca gttgaagaaa caaacgtcaa
     9481 acaaaatatt gatgattcag ttgaacaagc tgaagaaagt aaaggtcatt tacaagatga
     9541 agcaatagaa gaaacgtctg acgagaatgt tattgaagaa atagatccaa aagatcaaaa
     9601 aattaatgaa cttcaacaat tagcagatga aaacgaagag aaatatttaa ggctctacgc
     9661 tgagtttgaa aattataagc gtagaattca aaaagaaaat gaaataaaca aaacatatca
     9721 agcacaacgt gtgttaacag atattttacc agcaatagac aatatagaac gtgcacttca
     9781 aattgaaggt gatgatgaga cttttaaatc tcttcaaaaa ggtgtacaaa tggtgcatga
     9841 aagtttgatt aacgcactaa aagataatgg tcttgaagtt attaaaactg aaggtgaagc
     9901 atttgatcca aatattcacc aagctgtagt tcaagatgat aaccctgatt ttgaatctgg
     9961 cgaaatcact caagaactac aaaaaggata caagcttaaa gatagagtat taagaccatc
    10021 aatggtcaaa gtaaaccaat aacttaaatt tggcgaaaag acattgttta aaattaaatt
    10081 aatttaatga ttaaatggag gaattttatt atgagtaaaa ttattggtat agacttaggt
    10141 acaacaaatt catgtgtaac agtattagaa ggcgatgagc caaaagtaat tcaaaaccct
    10201 gaaggttcac gtacaacacc atctgttgta gctttcaaaa atggagaaac tcaagttggt
    10261 gaagtagcta aacgtcaagc tattacaaat ccaaacactg ttcaatctat taaacgtcat
    10321 atgggtactg attataaagt agatattgaa ggtaaatcat acacaccaca agaaatctca
    10381 gctatgattt tacaaaactt aaaaaataca gctgaaagct atttaggtga gaaagttgac
    10441 aaagctgtaa ttacagtacc tgcatacttt aacgatgctg aacgtcaagc aactaaagat
    10501 gctggtaaaa ttgctggttt agaagttgag cgtatcatta atgaaccaac agctgcagca
    10561 ttagcatatg gtttagacaa aactgataaa gatgaaaaag ttcttgtttt tgacttaggt
    10621 ggcggtacat ttgacgtatc tatcctagaa ttaggtgacg gtgtattcga agtactatca
    10681 acagccggtg acaacaaact tggcggtgat gattttgacc aagtaattat tgactaccta
    10741 gttgcagaat tcaaaaaaga aaatggtgta gacttatctc aagataaaat ggcattacaa
    10801 cgtttgaaag atgctgctga aaaagctaaa aaagacttat caggtgtatc acaaactcaa
    10861 atctcattac catttatctc agctggtgaa aacggtccat tacacttaga agtaaactta
    10921 actcgttcta aatttgagga attatcagat tcattaatta gaagaacaat ggaacctaca
    10981 cgccaagcaa tgaaagacgc tggcttaaca aactcagata tcgatgaagt tatcttagtt
    11041 ggtgggtcaa ctcgtattcc agcagtacaa gaagctgtca aaaaagaaat cggtaaagaa
    11101 cctaacaaag gtgtaaaccc agacgaagta gtggcaatgg gagctgcaat ccaaggtggc
    11161 gttatcacag gtgacgttaa agacgtagta ttattagacg taacaccact atctttaggt
    11221 attgaaattt taggtggacg tatgaatacg ttaattgaac gtaacactac gattcctaca
    11281 tctaaatctc aaatctattc aacagcagta gataatcaac catcagtaga tgtacacgta
    11341 ttacaaggtg aacgtccaat ggctgcggat aataaaacac ttggtagatt ccaattgact
    11401 gatattccac cagctgaacg tggtaaacct caaattgaag taacgtttga tatcgataaa
    11461 aacggtattg taaatgtaac tgcaaaagac ttaggtacaa ataaagaaca aagaattaca
    11521 attcaatcaa gttcttcatt atcagacgaa gaaatcgacc gtatggtaaa agatgctgaa
    11581 gttaacgctg aagcagataa aaaacgtcgt gaagaagtag acttaagaaa cgaagctgac
    11641 agcctagtat tccaagttga aaaaacttta actgatttag gcgaaaatat cggtgaagaa
    11701 gataaaaaat ctgctgaaga gaaaaaagac gctcttaaaa ctgctttaga aggtcaagat
    11761 atagaagata ttaaatctaa aaaagaagaa cttgaaaaag tgattcaaga attatcagca
    11821 aaagtatatg agcaagcggc tcaacagcaa caacaagcac aaagtgctaa tggtggtcaa
    11881 aacaacgata gcactgtaga agatgctgaa tttaaagaag taaaagacga cgacaaaaaa
    11941 taattaaaca atacaattag aatgttgtca tgatctgaaa agtcaaagtc aatagaacat
    12001 tggctttggc tttttatttg gatagtatga catattacgt taaactatat gagttaatta
    12061 agaaaaggag agatagctgt ggccaaaaga gactattatg aagttttagg cattagtaaa
    12121 gatgcttcaa aagatgaaat caaaaaagcg tatcgaaagc tttcgaaaaa atatcatcca
    12181 gatattaaca aagaagaagg tgcagatgaa aagtttaaag aaatttctga agcatatgaa
    12241 gttttaagtg atgataataa acgcgcaagc tatgatcaat ttggacatga cggtccgcaa
    12301 ggttttggcg gacaaggatt caatggctct gactttggtg gttttagtgg cttcggtggc
    12361 ggcggttttg aagatatctt tagctctttc ttcggtggcg gcagacaaag agatccaaat
    12421 gcaccgcaaa aaggtgatga tcttcagtat acaatgacat tgacatttga agaagcggta
    12481 tttggtacaa caaaagaaat ttcaatccgt aaagatgtaa catgcgaaac atgtcatggt
    12541 gatggtgcaa agcctggaac aagtaaaaag acttgtagtt actgtaatgg cgctggtcat
    12601 gtagctgttg aacaaaatac aattttaggt agagttcgta ctgaacaagt ttgtcctaaa
    12661 tgtaatggaa gtggtcaaga atttgaagaa gcttgtccaa catgtcacgg aaaaggtact
    12721 gaaaataaaa cagttaaatt agaagtgaaa gtacctgaag gtgtcgacaa tgaacaacaa
    12781 attagattag ctggtgaagg ctctccaggc gtgaatggag gacctgctgg tgatttatac
    12841 gtagtattta gagttaaacc atctgaaaca tttaaacgtg atggtgatga tatttattac
    12901 aaattaaatg ttagcttccc acaagcagct ttaggcgatg aaataaaaat accaacatta
    12961 aataatgaag ttatgttaac aatccctgct ggtacacaaa caggtaagca attccgctta
    13021 aaagaaaagg gtataaaaaa tgttcatggc tatggatacg gagatttata tgttgatatt
    13081 aaagtagtaa cgcctactaa attaacagat agacaaaaag aactaatgaa agaatttgcc
    13141 caattaaatg gtgaagaaat taatgaacaa ccttcgaatt ttaaagatag agcaaaaaga
    13201 ttctttaagg gagaataaag tatgaactgg acagagcttt caattattat taatcatgaa
    13261 gcagtagaat tggctaccaa tatacttgaa aatcatggat caaatggtgt cgtgatagaa
    13321 gattcagatg atttaattaa ccaaccagaa gataaatacg gtgaaattta cgctttgaaa
    13381 aaagaggatt atccagataa gggagtaaga ttgaaagcct attttaatga aatgacttat
    13441 gatgataagt tgcgacagca aattaaagat gagttattaa atttagatga acttgatcaa
    13501 cataacgttc aattcagtga gcaaattatt gcagagacgg attgggaaaa tgaatggaaa
    13561 aactatttcc atccattccg agcgtcgaag aagttcacaa tagttcctag ttgggaaaca
    13621 tatgctaaag aagcggatga agagctttgc attgagctcg acccaggtat ggcttttgga
    13681 acaggcgatc atccgactac aagtatgtgt ttgaaggcaa tagaaacata tgtattgcca
    13741 cagcattcag taattgatgt tggtactggc tcaggtatat taagtattgc aagtcatcta
    13801 atcggtgtaa aacgaattaa agcgttggat attgatgaaa tggcagtgag tgtagctaaa
    13861 gaaaacttca gaagaaatca ttgtgaaacg ttaattgaag ctgttccagg taacttattg
    13921 aaagacgaaa cagaaaaatt tgatattgta atagcaaata ttttagcgca tattattgat
    13981 gaaatgattg aagatgctta taatactcta aatgaaggcg gttattttat tacttctggt
    14041 attataaaag agaagtatga aggtatacag tcacatatgg agcgtgtagg ttttaaaatt
    14101 atttcagaac aacatgacaa cggttgggtt tgtcttgttg gccagaaagt gagtgaataa
    14161 tgtgcaacgt tatttcatag accaaaacgc tgatgtaagt cagcgttttt ttattacaaa
    14221 aaaagaagat attcatcata taacaaatgt aatgagatat gatgttggta gtaaaattat
    14281 tttaactttt aatgatcaaa cagtttattt atgtgaaatt gctgatataa caagtgataa
    14341 aattgcagtt gatttaaaag aaaaacaaaa tattaataca gaattgccag ttgatgttac
    14401 gatttgcagt ggactaatta aagctgacaa atatgagtgg ttgctacaaa aagctactga
    14461 attgggtgct tcatcattta tagctgtgag catggaacgc tcaattgtta aattaaacga
    14521 ggcgaaagtt gccaaaaaga tagagcgttg gcaaaaaata attaaagaag ctgctgaaca
    14581 aagctatcgt ttagtgattc catctattca attcgagtcg aatttaaaat taatttgtga
    14641 tactattgat aattatgact atattcttat tgcatatgaa gaggaagcaa aagatggtga
    14701 gttaagcaat ttcaagcaaa ctttacaaca attcaaggct caggataaag tgttgatgat
    14761 ttttggtcct gagggtggtt tgtcagaaaa tgaaatttca ttatttagta atactagtac
    14821 agttgttggt cttggaccga gaattttacg ggcagaaact gcaccattgt atgcgttaag
    14881 tgcaataagt tatgaaaatg aattaatggg gtgaatattt atgtcaacag ttgcgtttca
    14941 cacattaggt tgtaaagtaa accattatga aactgaagca atctggcaat tatttaaaga
    15001 agcaaactat gagcgcgttg actttgaagc gaatgctgat gtatttgtta ttaatacttg
    15061 tacagtaacg aatacaggtg ataaaaaaag tcgtcaaatt attagacgtg caataagaca
    15121 aaatcctgat gctgtaattt gtgtaacagg ttgttatgcg caaacttcat cagctgaaat
    15181 tatggaaatt cctggtgtcg atgtagtagt tggtacacaa gatagacata aactattagg
    15241 ttacattgat gaattccgta aagaacgcca accaattaat ggtgttggaa atatcatgaa
    15301 aaatcgtaaa tatgaagaat tagatgtccc atattttaca gatagaacac gtgcgtcatt
    15361 aaaaattcaa gaaggttgta acaacttctg cacattctgt attattccat gggctcgtgg
    15421 cttaatgcgt tcaagagatc cggaaaaagt agttgaacaa gcgacgcaac tagtgaattc
    15481 aggatataag gaaattgtat tgacgggaat tcatacaggt ggatatggtc aagatttaaa
    15541 agattataac ttggcccaat tattacgtga tcttgaaacg attaatggat tagaacgaat
    15601 tcgaatttct tcaattgaag caagtcaact tacagatgaa gtaattgacg ttttagaacg
    15661 ttcaacaaaa gttgtgcgtc atttgcatat tccattacaa tctggttcag atacagtatt
    15721 aaaacgtatg agacgtaagt atactatgga tagattttca gaacgattaa caaaattgca
    15781 taaagcttta ccagacttgg cagttacgag tgatgtaatt gttggtttcc caggtgaaac
    15841 tgaagcagag ttccaagaaa catatgattt tatcgtaaag cataagttct ctgaactgca
    15901 tgttttccct tattctccta gaattggcac gccagctgca agaatggatg accaaattga
    15961 tgaagaaatt aaaaatgaac gcgtgcataa gttaattacg ctaagcaatc aactcggaaa
    16021 gttatatgcg tctaaatttg atcaagatgt gcttgaagta attcctgagg aacagggtga
    16081 cacagaaggt acattagttg gatatgcaga taattatatg aaagtacaat ttgaaggtga
    16141 cgaatcactc ataggtcaaa ttgtaaaagt taaaattacg caagcaaatt atccattaaa
    16201 tgaagggcaa gcaattaaag ttgttgattt tgcaacaaat aaatctgata gagaagtttt
    16261 agtttaagta ttccttgatt cataccataa ggttccgtat taaagatata ggttttgtaa
    16321 cgttgtttta acggcttcac aatttactat ataagcaact cttctcatta aataaattat
    16381 taagagattt ttagaacaaa atcta
//
LOCUS       DAPSKH010000058        16293 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPSKH010000058 DAPSKH010000000
VERSION     DAPSKH010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 16293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16293
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.058"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..1676)
                     /gene="cna"
                     /locus_tag="RPH49_002114"
     CDS             complement(<1..1676)
                     /gene="cna"
                     /locus_tag="RPH49_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen adhesin Cna"
                     /protein_id="HDY5125242.1"
                     /translation="MNKNVLKFMVFIMLLNIITPLFNKNDAFAARDISSTNVTDLTVS
                     PSKIEDGGKTTVKMTFDDKNGKIQNGDTIKVAWPTSGTVKIEGYSKTVPLTVKGEQVG
                     QAVITPDGATITFNDKVEKLSDVSGFAEFEVQGRNLTQTNTSDDKVATITSGNKSTNV
                     TVHKSEAGTSSVFYYKTGDMLPEDTTHVRWFLNINNEKRYVSKDITIKDQIQGGQQLD
                     LSTLNINVTGTHSNYYSGSNAITDFEKAFPGSKITVDNTKNTIDVTIPQGYGSYNSFS
                     INYKTKITNEQQKEFVNNSQAWYQEHGKEEVNGKSFNHTVHNINANAGIEGTVKGELK
                     VLKQDKDTKAPIANVKFKLSKKDGSVVKDNQKEIEIITDANGIANIKALPSGDYILKE
                     IEAPAPYTFDKDKEYPFTMKDTDNQGYFTTIENAKAIEKTKDVSAQKVWEGSQKVKPT
                     IYFKLYKQDDNQNTTPVDKAEIKKLEDGTTKVTWSNLPENDKNGKAIKYLVKEVNAQG
                     EDTTPEGYTKKENGLVVTNTEKPIETTSISGEKVWDDKDNQDGKRPEKVSV"
     gene            2054..3472
                     /locus_tag="RPH49_002115"
     CDS             2054..3472
                     /locus_tag="RPH49_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDY5125243.1"
                     /translation="MENTVKYRKFILPIVVGLLIWALTPFKPDAVDPTAWYMFAIFVA
                     TIIACITQPMPIGAVSIIGFTIMVLVGIVDMKTAVAGFGNNSIWLIAMAFFISRGFVK
                     TGLGRRIALHFVKLFGKKTLGLAYSIVGVDLILAPATPSNTARAGGIMFPIIKSLSES
                     FGSKPKDGSARKMGAFLVFTEFQGNLITAAMFLTAMAGNPLAQNLASSTSNVHITWMN
                     WFLAALVPGLVSLIVVPFIIYKIYPPTVKETPNAKSWAENELATMGKIDLAEKFMIGI
                     FVIALTLWIVGSFIHIDATLTAFIALALLLLTGVLTWQDILNETGAWNTLVWFSVLVL
                     MADQLNKLGFIPWLSKSIATSLGGLSWPIVLVILILFYFYSHYLFASSTAHISAMYAA
                     LLGVAIAAGAPPLFSALMLGFFGNLLASTTHYSSGPAPILFSSGYVTQKRWWTMNLIL
                     GFVYFIIWIGLGSLWMKVIGIF"
     gene            complement(3885..4793)
                     /gene="rarD"
                     /locus_tag="RPH49_002116"
     CDS             complement(3885..4793)
                     /gene="rarD"
                     /locus_tag="RPH49_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDY5125244.1"
                     /translation="MNTEYKKGVFLALSAYILWGILPIYWQFVDAIGAFEILAFRIIF
                     SVIFMIFILAVGQKQRNAFQRDMNQLLAKPIQLLAIVVAGYVITLNWGTFIWAVTNGH
                     VLQTSLGYYINPLVSILLALIFLKERFNKFEWLAILFAFIGVLYMTLKIGEFPIVSII
                     LALSFGTYGLLKKVVHIDAISSITIECIVTAPAGLIYVIYLWQQHQMSFGLNMSSFWL
                     LFSGAITAIPLILFSAGAKRIPLSLIGFIQYVGPTIMFVLGIFVFKEPFSIDQLITFI
                     FIWTGIVLYSLSQYIKLKKHPVAKTL"
     gene            5014..5589
                     /locus_tag="RPH49_002117"
     CDS             5014..5589
                     /locus_tag="RPH49_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDY5125245.1"
                     /translation="MTLPKIGKPATRALNSQGIYTLEAVSQYTKSSLMEMHGVGPKAI
                     SILEQALFQHQLHFKTEVHSSLPFKLTGDVSCNHAPKRQQMIDFIVATAALDIELLRS
                     LVTTEFIWSVPGRFDIYGPQILIQELSNHYNQVASLNIHSSITHGCLGSMHGIEILKT
                     GKEIHFAHFFEFENHKKDAKLSKVTSYIVVD"
     gene            5755..6771
                     /locus_tag="RPH49_002118"
     CDS             5755..6771
                     /locus_tag="RPH49_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HoxN/HupN/NixA family nickel/cobalt transporter"
                     /protein_id="HDY5125246.1"
                     /translation="MTVFKNQRLSWLPYIAIVILLHVIGFSFLWIAGKDHHILFGMGI
                     LAYTLGLRHAFDADHIAAIDNTVRKLLQQRKDPSGVGFYFSIGHSSVVFLMAVFLGVS
                     VKWAKDELPHFQDIGGTIGTLVSGFFLVLIGVLNLIILISLINLFAKLRREHIEEAEV
                     DALLESRGLVSRFVGPYFKLITRSWHVLPLGFLFGLGFDTASEIALLALSSGASQQAI
                     SFIGILSLPILFASGMSLLDTLDGVVMKYAYNWAFFNPIRKIYYNITITAISVMAALV
                     IGMIELLQILADKLDLHGAFWAFIGSIEFDYLGYILVALFLITWLISSLIWKFGRIEH
                     KWSK"
     gene            7014..7814
                     /locus_tag="RPH49_002119"
     CDS             7014..7814
                     /locus_tag="RPH49_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylamine N-acetyltransferase"
                     /protein_id="HDY5125247.1"
                     /translation="MNIAKLEDYLQIEPTRYNQPSIEALNYYATRFMLTVPFENIDVQ
                     NGKPISVDIDALFNKIVHDKRGGFCYELNTFFKAYLQQKGFNPELMSATIHTPGGGRS
                     LNGSHASLVVSINDVFYVTDVGFGDLPLHVIPITSSEHTQPITDISGTFRAIFNNEDK
                     DIFYVQKFENDHWHTKYEAEFKPKQIEDFNSNIEYNQTNPDSIFVQHLLITMPQSFGR
                     ATMSENHLTLTKAKDGISEKLAVTKDNYKHFLEKYFGLDITINRIEKQ"
     gene            complement(7948..8460)
                     /locus_tag="RPH49_002120"
     CDS             complement(7948..8460)
                     /locus_tag="RPH49_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HdeD family acid-resistance protein"
                     /protein_id="HDY5125248.1"
                     /translation="MAKANQGIKWSSLIMGVLLLMLAVVIFTFPIENFYAITWLIGLF
                     VLINGVIQIIYRRKAKALVGGNQNWILFMGIVDILFGLIVIFNVGASSAFFIYMFAFW
                     FIFSSIAGLFTFTGSGSLKLISVIFNLLGIVFGVILLFNPLMGIVFISTMIAIAFVFV
                     GVIYVVDALA"
     gene            8750..9508
                     /gene="vraD"
                     /locus_tag="RPH49_002121"
     CDS             8750..9508
                     /gene="vraD"
                     /locus_tag="RPH49_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter ATP-binding
                     subunit VraD"
                     /protein_id="HDY5125249.1"
                     /translation="MTILSVQHVSKTYGKKHTFQALKDINFDIQKGEFVAIMGPSGSG
                     KTTLLNVLSSIDQISSGSVIANGQELNKLNQKALAKFRKESLGFIFQDYSILPTLTVK
                     ENIMLPLSVQKMSKATMEENYKAITTALGIYDLGNKYPSELSGGQQQRTAAARAFVHK
                     PQIIFADEPTGALDSKSANDLLQRLEEMNKSFDTTIVMVTHDPVAASFAERVIMLKDG
                     QIHTQLYQEGRSKQAFYEDIVHLQSVLGGVSNDI"
     gene            9498..11378
                     /gene="vraE"
                     /locus_tag="RPH49_002122"
     CDS             9498..11378
                     /gene="vraE"
                     /locus_tag="RPH49_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter permease
                     subunit VraE"
                     /protein_id="HDY5125250.1"
                     /translation="MTFNHIVLKNLRQNLKHYAMYLFSLFFSIVLYFSFTTLQFTKGV
                     NNDDSMAIIKKGALVGSIFLFIIIVIFLMYANHLFVKRRTREFALFQLIGLTRQNILK
                     MLALEQMIVFLITGVVGVLCGIAGAQLLLSIVSKLMSLSINLSIHFEPMALVLTIFML
                     IIAYVLILFQSALFLKRRSILSMMKDSIKTDVTTAKVTTAEIISGVLGIAMIALGYYM
                     ATEMFGMFKALTMAMTSPFIILFLTVVGAYLFFRSSVSLIFKTLKKSKNGRVSITDVV
                     FTSSIMYRMKKNAMSLTIIAIISAVTVTVLCFAALSKSNTDQTLTSMAPNEFNVVATQ
                     DAKQFETKLSQQQITFSKNAYETITVDNVKDQVITLENGSDSGRTNSILSANNKLTGN
                     NAIITNTKSLPNVINIHLNKDLVVKGTKNETFRVTQEDKGKVYPLNLSFNSPVVEVSP
                     EKYQQLKTQNNVHTFYGYDIKQTSQKEKAQAIAKQFGDKVITYDEMKKEVDATNGILI
                     FVTSFLGLAFLVAAGCIIYIKQMDETEDELSNFRILKRIGFTHTDMLKGLLLKITFNF
                     GLPLLIAILHAVFAAIAFMKLMGNISFMPVIVVIVVYTLIYITFALIAFVHSNKLIKK
                     TI"
     gene            11470..11661
                     /gene="vraH"
                     /locus_tag="RPH49_002123"
     CDS             11470..11661
                     /gene="vraH"
                     /locus_tag="RPH49_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter activity
                     modulator VraH"
                     /protein_id="HDY5125251.1"
                     /translation="MKFRELVKQSYEDLKNLTVTWYNVIALTMIVIVLSVVTTPIIGI
                     PAGLLGGAYYLKRREEKGK"
     gene            11712..12209
                     /locus_tag="RPH49_002124"
                     /pseudo
     CDS             11712..12209
                     /locus_tag="RPH49_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656145.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(12269..12766)
                     /locus_tag="RPH49_002125"
     CDS             complement(12269..12766)
                     /locus_tag="RPH49_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDY5125252.1"
                     /translation="MIINLETQQIHFDLEHEIPYFQAPEKNRIRLDIDVLNKKQISNI
                     INVIFNNQSKTKCTFLSEYLYPVKFREKTRIGRFFNITNWYEEIHSTDEKYVIATIKN
                     IKNKDLIDYSLYIKIGLVEPFIVFYNQENIFYISNAVIDIISVSKDTLDYIKSEFNDH
                     CASPY"
     gene            complement(12768..12857)
                     /locus_tag="RPH49_002126"
                     /pseudo
     CDS             complement(12768..12857)
                     /locus_tag="RPH49_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790915.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12869..13195
                     /locus_tag="RPH49_002127"
                     /pseudo
     CDS             12869..13195
                     /locus_tag="RPH49_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012656145.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            13224..13415
                     /gene="vraH"
                     /locus_tag="RPH49_002128"
     CDS             13224..13415
                     /gene="vraH"
                     /locus_tag="RPH49_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide resistance ABC transporter activity
                     modulator VraH"
                     /protein_id="HDY5125253.1"
                     /translation="MKFRELVKQSYEDLKNLTVTWYNVIALTILVIVLSSFTTPMIGI
                     PAGLLGGSYYLKRREEKGK"
     gene            13808..14008
                     /locus_tag="RPH49_002129"
     CDS             13808..14008
                     /locus_tag="RPH49_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDY5125254.1"
                     /translation="MNNGTVKWFNAEKGFGFIEQENGGDVFVHFSGIASDGYKTLEEG
                     QKVTFEITEGQRGDQAVNVQTV"
     gene            complement(14126..14695)
                     /locus_tag="RPH49_002130"
     CDS             complement(14126..14695)
                     /locus_tag="RPH49_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125255.1"
                     /translation="MNLSKQIKKYRERDGYSQEYLAEKLYVSRQSISNWENDKSLPDI
                     HNLLMMCELFNVTLDDLVKGTIPFVPDIKVQRSLNLWTYVMLIFMTLAAILMGPLVVY
                     WNWTWGITVAIILGIGFYASMKIEDLKKVHKMDNYDRIVAFMNGKDPSEVQTTKARNT
                     MTNALSIISVVGTLSLIIFLSVYLANKFL"
     gene            complement(14955..15350)
                     /locus_tag="RPH49_002131"
     CDS             complement(14955..15350)
                     /locus_tag="RPH49_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3147 family protein"
                     /protein_id="HDY5125256.1"
                     /translation="MKLTLMKFFVGGFAVLLSYIVSVTLPWKEFGGIFATFPAVFLVS
                     MFITGMQYGDKVAVHVSRGAVFGMTGVLVCILVTWMMLHMTHMWLISIVVGFLSWFIS
                     AVCIFEAVEFIAQKRLEKHSWKAGKSNSK"
     gene            complement(15418..15771)
                     /locus_tag="RPH49_002132"
     CDS             complement(15418..15771)
                     /locus_tag="RPH49_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3147 family protein"
                     /protein_id="HDY5125257.1"
                     /translation="MFSIGSAILHFVIGGIAVALASIIADKVGGKLGGIIATMPAVFL
                     AAIIALALDHRGTQLVEMSMNLSTGAIVGILSCILTVFLTSLYIKHKGYRKGAIFTVV
                     CWFVISLAIFSIRHL"
BASE COUNT         5378 a         2836 c         2477 g         5602 t
ORIGIN      
        1 acactgactt tttctggtct cttaccatct tgattgtctt tgtcgtccca tactttttca
       61 ccgctaattg atgttgtttc aattggtttt tcagtattag taaccactaa accattttct
      121 tttttagtat atccttctgg tgttgtatct tcaccttgag catttacttc tttaactaaa
      181 tatttaatag ccttgccatt tttgtcattt tctggaagat tagaccatgt cacttttgtc
      241 gttccatctt ctaatttttt aatctctgct ttgtctactg gtgttgtgtt ttgattgtca
      301 tcttgtttgt acaacttgaa ataaatcgtt ggtttcactt tttgagatcc ttcccaaacc
      361 ttttgagcag aaacatcttt tgttttttct atcgcttttg cattttcaat agtcgtaaaa
      421 tatccctgat tatctgtatc tttcatagta aacggatatt ctttatcctt atcaaatgta
      481 tacggtgctg gcgcctctat ttcttttaaa atatagtctc cactaggcaa cgctttaata
      541 ttagcaatac cgtttgcatc tgttataatc tcaatttctt tttgattgtc ctttacaact
      601 gatccatctt ttttagaaag tttaaatttt acattagcta taggagcctt ggtatcttta
      661 tcctgtttta aaacttttaa ttcacctttt acagtacctt caataccagc attagcatta
      721 atattgtgca cagtatgatt aaatgatttc ccgttcactt cttccttacc atgctcttga
      781 taccaagctt gtgaattatt aacaaactct ttttgctgtt cattcgtaat tttggttttg
      841 tagttaattg aaaaactatt atatgaccca tagccttgtg gaattgttac atcaattgtg
      901 ttcttcgtat tatcaacagt tattttagaa cctggaaaag ctttttcaaa atcagtaatt
      961 gcatttgatc cactataata attgctatgt gtacctgtca cattaatgtt taatgtgctt
     1021 aaatctaact gctgtccacc ttgaatctga tcctttatag ttatatcttt cgatacatat
     1081 cttttttcat tattaatatt taaaaaccat cgtacatgtg tcgtatcttc tggcagcatg
     1141 tctccagttt tataatagaa aacactactt gttcccgctt cacttttatg aaccgtaaca
     1201 ttcgttgatt tattcccaga tgttatcgta gctactttgt catctgaagt atttgtttgc
     1261 gttaaatttc ttccttgtac ttcaaattct gcaaatcccg aaacatcact taatttttct
     1321 actttatcat tgaatgtaat tgttgctccg tctggtgtaa taactgcttg acccacctgt
     1381 tcacctttaa cagttaatgg tactgtttta ctataaccct ctatctttac tgtaccgctt
     1441 gtcggccatg ccactttaat cgtgtcacca ttttgtattt ttccattttt atcgtcgaat
     1501 gtcattttta ctgtcgtttt accaccatct tctatcttag acggtgatac agttaaatct
     1561 gtaacattcg ttgatgaaat atctcgtgct gcaaatgcgt catttttatt aaataaaggc
     1621 gtgatgatat ttaataacat tataaagacc ataaacttca acacattctt gttcataaaa
     1681 acccctcctt ataatctatg tcatatccat aggatactaa tgataaatta taaactaatt
     1741 tagttcttat tcaatggaat ttatcaaaaa ttcatattat tattttatta tgcaaaatat
     1801 atacagtata acgaatacaa gtgcatgaag ttaacttgta tcaattaatt tcttagtata
     1861 ttagttcatt ttcaaaatct tttaaattta ataaacacca tctataccag ttcttcaccg
     1921 attatcgaaa aataattata ttaatgattt cgttaattta attttatatt taattattac
     1981 tgtacatctt ttgtagttag ctttattctt aaattgaaat atgtataaaa catagaaaga
     2041 aggacgtttt aacatggaaa acacggttaa atatcgtaag tttatactcc ctatcgttgt
     2101 aggtctcctt atttgggcac ttacaccttt taaaccggat gctgtggatc caacagcatg
     2161 gtatatgttc gcaatattcg tcgcgacaat cattgcttgt attacacaac cgatgccaat
     2221 tggggccgtc tctataattg gatttacaat catggtactc gttggaattg ttgacatgaa
     2281 aacggctgtc gctggttttg gtaataatag catttggtta attgctatgg catttttcat
     2341 ttcgagagga tttgtgaaaa caggtcttgg tagacggatc gcacttcatt tcgtcaaatt
     2401 atttggtaaa aaaacattag gattagcata ttctatcgtc ggtgtagatt taattctagc
     2461 gcctgctaca ccaagtaata ccgcgcgtgc tggtggaatc atgttcccaa ttatcaaatc
     2521 actttctgaa tcatttggtt cgaaaccgaa agacggatca gcacgcaaaa tgggtgcatt
     2581 tcttgttttc acagaattcc aaggtaattt aattactgcg gctatgtttt taactgcaat
     2641 ggccggtaac ccccttgcac aaaatttagc atctagcaca tctaatgttc acattacatg
     2701 gatgaattgg ttcctagctg ctttagttcc tggacttgtt tccttaattg ttgtaccttt
     2761 tattatttat aaaatttatc caccaactgt taaagaaaca ccaaatgcta agagttgggc
     2821 tgaaaatgaa ttagcgacta tgggtaaaat cgatttagct gaaaaattta tgattggtat
     2881 ttttgtcatt gctctaacat tatggattgt tggaagtttc attcatattg atgcaacttt
     2941 aacggccttt attgcgctag cattgttatt attgacaggc gtcttaacat ggcaagacat
     3001 tttaaacgaa acaggtgctt ggaacacatt agtatggttc tcagtattag tgttaatggc
     3061 cgaccaatta aacaagcttg gatttattcc ttggttaagt aaatccattg ctacaagtct
     3121 tggtggctta agctggccta tagtactggt cattttaata ttgttctact tctattcaca
     3181 ttacttattt gcaagttcta cagcacatat cagtgcgatg tatgcagcat tactaggcgt
     3241 tgccatcgca gccggtgcac caccattatt cagtgcatta atgttaggtt tcttcggtaa
     3301 cctattagct tcaacaacac actatagtag tggtccagcg ccgattctat tctcttcagg
     3361 ttacgtgact caaaaacgtt ggtggacaat gaacttaata ttaggtttcg tctactttat
     3421 tatctggatt ggtttaggat cactttggat gaaagtaatt ggtatatttt aaaatattta
     3481 aattagcgct cgaatctcat tgatttgggc gctttttaat ttgtatttaa aatcaatctt
     3541 tgctaaatca agactccctt tttaaaatac gtttatcctt taaatcattg cctacttcac
     3601 tgaaaatttg tataaagatt taagtcatta cgtaacatca cataaaatac atttctatac
     3661 taatccgttt cattgatcaa cattacgtat gccctcataa atcatgaaat aaaaaacacc
     3721 ttcgtttaaa ttcattttaa gtgcgaattc aacgaaagtg ctttatttca tatttaatgt
     3781 ttcaaattta tacggctatc actgttactg cacacatacc tcagtctcac cttatcatga
     3841 cacaaaggaa attgaaaaca cgtataatta tctctcctcg tattttatag ggtttttgcg
     3901 accggatgtt tcttcaattt aatgtattga gaaagactat ataacacaat acctgtccaa
     3961 ataaatataa acgtaattaa ttgatctata ctaaaaggct ctttgaaaac aaatatgccg
     4021 agtacaaaca ttattgttgg tccaacgtat tgaataaatc ctattaacga aagtggaata
     4081 cgttttgccc cggctgagaa taggattagt ggtattgccg taatagcacc agaaaataac
     4141 aaccaaaatg atgacatgtt caatccaaat gacatctgat gttgctgcca taaataaata
     4201 acgtatatga gtccagcagg tgcggtaaca atacattcaa tcgtaatact gctgatggca
     4261 tcaatatgta ctactttttt caataatcca tatgtaccaa aggataacgc taatataata
     4321 gagacgattg ggaattctcc aattttcagt gtcatatata atacaccgat gaatgcgaat
     4381 aaaatggcta gccattcaaa tttattgaat ctttctttta aaaagataag tgcgagcaaa
     4441 atgctaacaa gtggatttat ataataacct aaacttgttt gtaggacgtg tccgttcgtt
     4501 acagcccaaa taaatgtacc ccaatttaat gtaatgacat agcctgctac gacaattgct
     4561 agtaattgaa tgggcttggc taacaattga ttcatatctc gttgaaatgc attgcgttgt
     4621 ttttgtccaa ccgcgagtat gaaaatcatg aatattactg aaaatataat acgaaaggct
     4681 aaaatttcaa atgcgcctat tgcatcaacg aactgccaat atataggtag tattccccac
     4741 agaatgtatg cactgagtgc taaaaataca ccttttttat attctgtatt cacttacata
     4801 cctccttact ctcccaattt ttaacatgtt acgctcactt agttaagcta atataacgat
     4861 tttactaata atatttcgat aaagatatca ttttgtttat atttcccaca tttattcacc
     4921 aaccactaaa caatattaat tttataaata attctgtaca aatcagggta tattgccaga
     4981 aagactacca tacaacataa aggatggata caaatgactt tacctaaaat tggaaagcct
     5041 gcaacacgcg cgctaaattc acaaggtata tacacattag aagcagtatc acaatatacg
     5101 aagtcatctc taatggagat gcatggcgtt ggtcctaaag ctatatcaat attggaacaa
     5161 gctttatttc agcaccaact acattttaaa acggaagttc attcatcatt accttttaag
     5221 ttaacaggag atgtgtcatg caatcatgcg cctaaacgtc aacaaatgat agattttata
     5281 gttgctacag cagcattaga tattgaatta ttacgttcac tggttacaac agaatttatt
     5341 tggtctgtcc ctggccgctt tgacatatac ggacctcaaa tattaattca agaactatct
     5401 aatcattaca atcaggttgc tagtctcaat atccattcca gcatcacaca tgggtgctta
     5461 ggttccatgc atggtattga aatattaaaa actggtaaag agattcattt tgctcatttt
     5521 tttgaatttg aaaatcataa aaaggatgcc aagttaagca aagtgacatc ttacattgtt
     5581 gttgattaat gtatcaaatt atatatatct caaaaaattc ttttgcggtt acatgtatat
     5641 ttttatataa aaaataattt tgtataacat ttttgttata tgaacattta ttactagagt
     5701 gcacattgaa catacagtat gattaaatat catgttatga aagaaggata tattttgact
     5761 gtttttaaaa atcagcgttt aagctggtta ccatacatag ctattgtcat tttgttacac
     5821 gttattgggt ttagtttttt atggattgct ggaaaagacc atcatatctt atttggtatg
     5881 gggattcttg catatacatt aggtttgcgt catgcatttg atgcagatca tatcgccgcg
     5941 atagataata cggttcgcaa attattacag caacgcaaag atccatctgg tgtaggtttc
     6001 tatttttcaa ttggacattc atctgtcgta tttttaatgg ctgttttttt aggggtatct
     6061 gtaaaatggg ctaaagatga attaccgcat ttccaagata ttggtggaac gattggtaca
     6121 ctagtttcag gtttcttttt agtgcttatc ggtgtgttga atctaattat tttaatctct
     6181 ttaattaact tgttcgctaa attacgtcgt gaacacattg aagaagctga agtcgatgca
     6241 ttacttgaat ctagaggatt ggtttctcga tttgtaggac cttatttcaa attaatcacg
     6301 cgtagttggc acgtattgcc acttggcttt ttatttggac ttggttttga tacagctagt
     6361 gaaattgcgt tactcgctct ttcttcaggc gcatcacaac aagccatttc atttatcgga
     6421 atcttatctt taccaatttt attcgcatca ggtatgagtt tattggatac attagatggt
     6481 gttgtaatga agtatgccta taattgggca ttcttcaatc ctattcgcaa aatctattac
     6541 aatataacga ttactgcgat atcagtcatg gcagcattag tgattgggat gattgaattg
     6601 ctacaaattc ttgctgataa gctagattta catggtgcgt tttgggcatt cattggttcg
     6661 atcgaatttg attatttagg ttatatttta gttgcattat ttttaattac ttggcttatt
     6721 tcaagtttaa tttggaagtt tggtcgcata gaacacaaat ggtctaaata aagtaacttg
     6781 tcttgcaact acctttgtat tgttgcattt ttagacaccc tgcatactga ctcatttagg
     6841 atatgctctc tgttgtcatc tttaaatcgt ttcttttaga gatgacttca ttttgagagc
     6901 gtatttttct atttaaaatg tatttatcca aaattcaatg ctttcgaatt taaaatttca
     6961 gcatttctgt ttaaaattta attataatct ttaatacagg aggcggtata ctaatgaata
     7021 ttgcaaagtt agaagattat ctccaaattg aaccaactcg ttataatcaa ccgagtattg
     7081 aagcattaaa ttattatgcg actcgcttta tgttaacggt gcctttcgaa aatattgatg
     7141 ttcaaaatgg taaaccaata tctgtagata tcgatgcact tttcaataaa attgttcatg
     7201 ataaacgcgg tggtttttgt tatgagttaa atacattttt caaagcatat ttacaacaaa
     7261 aaggatttaa tcctgaatta atgtcagcta ctattcacac acccggtggc ggtcgtagtc
     7321 tgaacggttc acatgcttca cttgttgttt ctataaatga tgtattctat gtaactgatg
     7381 ttggctttgg agacttacct ctacatgtca ttcctattac ttcatctgag catacacaac
     7441 caattactga tatcagtggt acattccgcg ctatttttaa caacgaagac aaggatattt
     7501 tctatgttca aaaattcgaa aatgatcatt ggcatacaaa atatgaagct gaattcaaac
     7561 ctaaacaaat agaagatttt aatagcaaca tcgaatataa ccaaaccaac ccagattcaa
     7621 tatttgtaca gcatttatta attacaatgc cacaatcatt tggacgcgct acaatgtctg
     7681 aaaatcattt aactttgaca aaagcaaagg atggcatctc agaaaagtta gctgtcacta
     7741 aagataacta taaacatttt ttagaaaaat attttggact agatataact attaatcgta
     7801 ttgaaaaaca ataatagtaa aatataaaaa tatgggcgta tcttacttat tgtaggtagc
     7861 gccccttttt tatgcttcat aaacacaaca aaaaggatat gacacaaact tcatgtcaca
     7921 cccttctttt gaaccgcttc attttactta agcaagtgca tctacaacat aaatgacacc
     7981 tacgaataca aatgcaatag caatcatcgt cgaaataaag acgataccca ttaatggatt
     8041 aaataataaa atgacaccga aaacaatacc taataaatta aaaatcactg aaattaattt
     8101 taagctacca ctacccgtaa acgtaaataa tcctgcaata gaactaaaaa tgaaccagaa
     8161 tgcaaacatg tagataaaaa atgccgagct agcgccaaca ttaaaaatga caataagacc
     8221 aaagagaata tctacaatcc ccataaacag aatccaattt tggttaccac ctactaaagc
     8281 ttttgctttt ctacggtaaa tgatttgaat cacaccgtta attaatacaa acagtccaat
     8341 caaccaggta atagcataaa aattttcaat tgggaatgta aaaataacaa ctgccaacat
     8401 taataataat acacccatta ttaaactaga ccatttaata ccttggtttg cttttgccat
     8461 aaaaatcaat tcctttcaaa taaagccctc tttatatttt cattagtgcc actattattc
     8521 attgtttaaa ttccctcatc ttaacttata gaaacatttc ctcactgcta atactgtgat
     8581 gctcagatta gttgaattgc tttccaataa tccaaattca cccgagaaaa tcacgatata
     8641 ttaatatctt tcaactatgg aagattcaaa cattgaattg taagtttaga taaaggctac
     8701 tactccaaac attatttaaa atgaaattaa atacaaaagg agtgatacta tgacgatatt
     8761 atcagtgcaa catgtttcaa aaacatacgg taaaaagcac acatttcaag cacttaaaga
     8821 tattaacttt gacatacaaa aaggcgaatt cgttgcgatt atggggcctt ctggatcagg
     8881 taagacaacc ttattaaatg tactaagttc aattgaccaa atttctagcg gtagcgtgat
     8941 tgctaacgga caagagctta ataaacttaa tcaaaaagca cttgccaaat tccgtaaaga
     9001 atcattaggt ttcatcttcc aagattacag tattctgccg acattaactg ttaaagaaaa
     9061 cattatgtta cctttatctg ttcaaaaaat gtcgaaagca acaatggaag aaaattataa
     9121 agcgattact acagcattag gtatttatga cctgggaaat aaatacccta gcgaattatc
     9181 tggtggtcaa caacaaagaa ctgcagcagc gagagcattt gttcataaac cacaaatcat
     9241 atttgcagat gagccaacag gcgcactcga ctcgaaaagt gcaaatgact tattacaacg
     9301 tttggaagaa atgaataaat cgtttgatac aactattgtc atggttacac atgatccggt
     9361 tgcagcaagt tttgcagaac gtgtcatcat gctaaaagat ggccaaattc atacacaact
     9421 ttatcaggaa ggacgttcta aacaggcctt ttatgaagac attgtacatc ttcaatcagt
     9481 attaggtggt gtctcaaatg acatttaacc atatcgtttt aaaaaactta cgtcaaaact
     9541 taaaacatta tgcaatgtat ttattttcat tattttttag catcgtctta tatttcagtt
     9601 ttacaacctt acagtttact aaaggtgtaa ataatgatga ctcgatggcc atcattaaga
     9661 aaggtgcttt agtcggatca atatttttat ttatcattat tgtcatcttt ttaatgtatg
     9721 ccaatcattt attcgtgaaa cgccgtacac gtgaatttgc gctatttcag ttgattggtt
     9781 taacacgaca aaacattttg aaaatgttag cacttgaaca aatgattgta tttttaatca
     9841 caggtgttgt cggtgtatta tgtggcattg caggtgcaca attattgctt tccattgtat
     9901 ctaaattgat gtcgttatcg attaacttat cgatacattt cgaacctatg gcccttgttt
     9961 taactatttt catgctaatt attgcgtatg tactgatttt atttcaaagt gctttatttc
    10021 taaaaagacg tagtatctta tcaatgatga aagactcaat taaaactgat gttacaactg
    10081 ctaaagtaac gactgcagag attatttcag gcgtattagg tattgctatg attgcactag
    10141 gatattatat ggcgacagaa atgtttggta tgttcaaagc actaactatg gctatgacat
    10201 caccgtttat cattttattt ttaacggttg taggcgccta tttattcttc agaagttccg
    10261 tgtcacttat ttttaaaaca ttgaaaaaat caaaaaatgg acgcgtatct attaccgatg
    10321 ttgtattcac atcgtctatt atgtacagaa tgaagaaaaa tgccatgtct ttaactatca
    10381 ttgcaattat ttctgcagtt acagtaactg tattgtgttt cgcggcatta tctaaatcaa
    10441 atacagatca aacccttaca tctatggcac caaatgaatt taacgtggtc gctactcaag
    10501 atgctaaaca atttgaaact aaactaagcc aacaacaaat tacattttct aaaaatgctt
    10561 acgaaactat tactgtagat aatgttaaag atcaggttat tactttggaa aatggtagtg
    10621 attcaggtcg cacgaattca atattaagtg caaataacaa gttaacaggc aacaatgcca
    10681 tcattacaaa tacaaaatcg ctgcctaacg tgattaatat tcatttaaac aaagatttag
    10741 tagtaaaagg tacaaagaac gagactttcc gtgttacaca agaagacaaa ggtaaggttt
    10801 atcctttaaa tctaagcttc aactcacctg tcgtcgaagt aagtcctgaa aagtatcagc
    10861 agttgaaaac acaaaataac gttcatactt tttatggata tgatattaaa caaacatcac
    10921 aaaaggaaaa agctcaagca attgcaaaac agtttggaga caaagtcatc acgtatgatg
    10981 aaatgaaaaa agaggtcgat gctactaacg gtattctaat atttgttaca tcatttttag
    11041 gattagcatt tttagtagca gctggatgta ttatttatat taaacaaatg gatgaaactg
    11101 aggatgaact aagtaacttc agaatattaa aacgcatagg ctttacgcat acagatatgc
    11161 ttaagggatt attattaaaa attactttca acttcggttt accattattg attgctatat
    11221 tacatgcagt attcgccgca atagcattta tgaaattgat gggtaatatt tccttcatgc
    11281 cggttattgt agtaattgtt gtatacacac tcatttacat tacttttgct ttaattgctt
    11341 ttgtacattc aaacaaattg attaagaaaa ccatttaaca cttacgatta aaagatgctt
    11401 cattgagatt ttgattttaa gcaatgcagt ataactatta actgatttat aaaaaggaga
    11461 gattgaatca tgaaatttag agaattagta aaacaatcat acgaggattt gaaaaatttg
    11521 actgtaactt ggtataacgt cattgcttta acaatgattg ttattgtctt aagcgtagtt
    11581 acaacaccaa ttataggtat tccagctggt ttattaggtg gcgcttatta tttaaaacgc
    11641 cgtgaagaaa aaggtaaata aataagcctt ctgtgctaaa ctcaatatgt atttcctacc
    11701 aaagaaaaca taaggagtta ggacatcttg aaggagatac tattgttggt cgtcgtcatg
    11761 gtagtgcatt cattactttg gtagaaagag tatccaagat gattatcacc ttacgaccct
    11821 taggtcgtaa ggcaactgat atagaaaacg ctctacactc aatgttttca tctttacctt
    11881 ctcatatatt taaatcaatt acttttgatt gtggtaagga gttctcaaac tggaaaacaa
    11941 taagcaactg tcacaatata tctatatttt ttgctgatcc aagcacgcca tcacagcgag
    12001 gtttaaatga acattctaac ggaatactta gacgcagtgg attaaataaa gaactagatt
    12061 tcaatttagt aacggatgat catatcatca gtgttgctca aaaaatcaat catcatccta
    12121 gaaaatcttt aggttataga acaacattgg aagtatttat gagtttcatc gaagatgata
    12181 aacttgtcca gcttaatttg acaatctaaa gctatataaa aaagccgttg gtctcttcga
    12241 aactacggct tttctctgtg ctataaaatc agtatggcga agcacagtga tcattgaatt
    12301 ctgactttat ataatcaaga gtatctttgg atacactgat gatatctata acagcattgc
    12361 taatgtagaa tatattttct tgattataga atacaataaa tggctccact aaacctattt
    12421 taatatataa agaataatca attaagtctt tgttttttat atttttaata gttgcaataa
    12481 catacttctc atcggtagaa tggatttctt cgtaccagtt agtaatatta aaaaaacgac
    12541 caattcttgt tttttctcta aatttaacag gatataagta ttcagacaaa aatgtacatt
    12601 tcgtctttga ttggttatta aatataacat taataatatt agaaatttgc tttttattga
    12661 gaacatcaat atctaagcgt atcctatttt tctcaggtgc ttgaaaatag ggaatttcat
    12721 gttctaaatc aaaatgtatt tgttgtgttt caaggttaat aatcatttta atctccaatt
    12781 ctttttaggt tagcatcgta tgtaccactt cttgttttct tgctacctaa attattaata
    12841 ctgcttgcac ctttccattt tatcttctca tatatttaaa tcaattactt ttgattgtgg
    12901 taaggagttc tcaaactgga aaacattatg taactgtcac gatatatcta tattttttgc
    12961 tgatccaggc acgccatcac agcgaggttt aaatgaacat tctaacggaa taattagacg
    13021 cagtggatta gataaagaac tagatttcaa tttagtaacg gatgatcata tcatcagtgt
    13081 tgctcaaaaa atcaatcatc atcctagaaa atctttaggt tatagaacac cattggaagt
    13141 atttatgagt ttcatcgaag atgataaact tgtccagctt aatttgacaa tctaaagatt
    13201 tataaaaaag gagagattga atcatgaaat ttagagaatt agtaaaacaa tcatatgagg
    13261 atttgaaaaa tttgactgta acttggtata acgtcattgc tttaacaata cttgttattg
    13321 tattaagctc attcacaaca ccaatgatag gcattccagc tggtttatta ggtggctcct
    13381 attatttaaa acgtcgtgaa gaaaaaggca agtaagcaca ttccatcggt atagaacatt
    13441 gctatgacct ttcaagtcag attttaatat caacaagtag cgtttatcgc tgcttgtttt
    13501 ttatggattg cttataaaat catcatgttt aaacgatatg tcactttgaa aactagcaaa
    13561 caccataaaa gactacaatt tttttatttt tataaacccc tttaaatcaa cgtttctaag
    13621 gtttttaaaa atctttttta atttattttc aaaaaacact gtacattatg ccaatatgag
    13681 cgtatagttg gtcttacgta ataaaagctc gtgaattaaa ttgtagtgta tttgtttaga
    13741 atatcctctt ttttagttat gaatttgtta caaatattaa gtgcaaaagc acatggaggt
    13801 tttctatatg aataacggta cagtaaaatg gtttaacgca gaaaaaggtt ttggtttcat
    13861 cgaacaagaa aatggcggag acgtattcgt acatttctca ggtatcgcta gcgatggcta
    13921 caaaacttta gaagaaggtc aaaaagttac tttcgaaatc actgaaggtc aacgtggaga
    13981 ccaagcagtt aacgtacaaa ctgtttaatc ttacaaaata aaacgactca ttataaatga
    14041 atcgctttga ttaccaacaa ggtttagaac cttgttggta tttttttatg ctatttcgga
    14101 taatatgaga cgatacgatg atgatttata aaaatttatt tgccaaatac acactaagga
    14161 aaattatgag gctgagtgta ccaactactg atataataga aagcgcattt gtcatcgtat
    14221 ttctagcttt agtcgtttgt acttcactag gatcttttcc attcataaaa gcaacaattc
    14281 gatcgtagtt gtccatttta tgcacttttt ttaaatcttc tattttcata gatgcataaa
    14341 agcctattcc caaaatgatt gccaccgtta taccccaagt ccaattccaa taaacaacta
    14401 aaggtcccat taaaattgca gctaatgtca tgaaaataag catcacatat gtccataagt
    14461 taagacttcg ttgcacttta atatcaggta caaatggaat agtccctttt actaaatcat
    14521 ctaaagttac attgaacaat tcgcacatca ttaataagtt atgtatgtct ggtaagcttt
    14581 tgtcattttc ccaattagaa atactctgcc tagatacata taacttttca gcaagatatt
    14641 cttgtgaata accatctcgt tccctatatt ttttaatttg tttactcaga ttcaattaca
    14701 tacgcctcca ttcaattagt acaatcatta caatcagact atcagataaa gttaaatcaa
    14761 gtcacctgta tgattgacta aatgttttga catacgacaa catcggggtt cgaagactcc
    14821 cttaagacag acctgtatga ttacgcgctt gtaattttct caatgccaac ttgaatttca
    14881 cttattaatg atgcaacttt tccatgctat tcaatgcttg caaagttagt cctagttaag
    14941 agattacgtt cacactattt actattcgat tttccagctt tccaactatg cttttctaat
    15001 cttttttgtg ctataaattc taccgcttca aaaatacata ctgcactgat gaaccagctt
    15061 aggaaaccaa caacaatgct aatcaaccac atgtgcgtca tatgtaacat catccatgta
    15121 actaaaatac aaactaatac ccctgtcata ccaaacactg cgccacgact tacatgcaca
    15181 gcgactttat caccatattg catacctgta ataaacatag acactaaaaa tactgccgga
    15241 aacgttgcaa atataccgcc aaattctttc caaggtagtg ttacagatac aatataactt
    15301 aataatactg caaatccccc cacaaaaaat ttcattaatg ttaatttcat gatgttctgc
    15361 ctccaataat ttattactta ataactgaat acaactaatt atcacgcatt ttccaaacta
    15421 taaatgtcta atactgaata ttgcgaggga aatgacaaac caacaaacaa ctgtgaatat
    15481 tgcgcctttc cgataacctt tatgcttaat gtagagagat gtcaaaaata cagttaatat
    15541 acaagacaga ataccgacaa ttgctccagt actaagattc atcgacatct ccactaattg
    15601 cgtaccacga tgatctaaag ctaatgcgat aatagccgca agaaagactg ccggcatagt
    15661 agctataata cctcctaact taccacctac cttatcagca ataattgaag ctaatgcaac
    15721 agcgatacca ccaatgacaa aatgaagaat tgcacttcca attgaaaaca tcttcaacgt
    15781 acctttctat aattaattca atacaaaacg tatcattcac acaaagtgta aaacttaaat
    15841 tttctactgt aaaggcaact caagcgatgt tcataaagct ttcatgatac tttcataaac
    15901 tagcaataaa gggttcaaat gaaagtatat ccagctcaaa ttaaggagtg ggacagaaat
    15961 gatattttcg caaaatttat ttcgtcgtcc caccccagca aggttgacta gaattgaaaa
    16021 aagcttgtta caagcgcatt ttcgttcagt caactactgc caatataact tcgtagagca
    16081 tagaacattg atttatgtac cagcctgatc aacatataaa tataaatttt tatgtttcac
    16141 gtaaaacaaa tcaaaaccac ccgtgtgaac gggtggtttg ttcagcggct ataagccttc
    16201 cttactggcc agccctaaaa gggcactgaa aagtcagcca actgcactac tattccagca
    16261 accctaaagg gttactcttt tttctttctt ttt
//
LOCUS       DAPSKH010000059        16087 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPSKH010000059 DAPSKH010000000
VERSION     DAPSKH010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 16087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16087
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.059"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            797..1171
                     /locus_tag="RPH49_002133"
     CDS             797..1171
                     /locus_tag="RPH49_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SarA family transcriptional regulator"
                     /protein_id="HDY5125258.1"
                     /translation="MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYIS
                     ENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRK
                     KIESLLSRVNKRITEANNEIEL"
     gene            complement(1422..2210)
                     /locus_tag="RPH49_002134"
     CDS             complement(1422..2210)
                     /locus_tag="RPH49_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5125259.1"
                     /translation="MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLA
                     SSYNVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLF
                     TDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEK
                     TMKWYQKQRIYSTKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDK
                     NHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLNFLKSVS"
     gene            complement(2379..3095)
                     /locus_tag="RPH49_002135"
     CDS             complement(2379..3095)
                     /locus_tag="RPH49_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125260.1"
                     /translation="MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKD
                     QDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMS
                     LFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIP
                     ITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIW
                     ILLVVLVIYFTIRLSSRTRL"
     gene            complement(3257..3763)
                     /locus_tag="RPH49_002136"
     CDS             complement(3257..3763)
                     /locus_tag="RPH49_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125261.1"
                     /translation="MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQ
                     SLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTH
                     ISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIK
                     LYRIDLEK"
     gene            complement(3899..4699)
                     /locus_tag="RPH49_002137"
     CDS             complement(3899..4699)
                     /locus_tag="RPH49_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5125262.1"
                     /translation="MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAELA
                     KSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADI
                     SVRYPEFTSSLTLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRK
                     MNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLE
                     AKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV"
     gene            complement(4683..5402)
                     /locus_tag="RPH49_002138"
     CDS             complement(4683..5402)
                     /locus_tag="RPH49_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5125263.1"
                     /translation="MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQL
                     ADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTL
                     YTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFED
                     MIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVE
                     ELLTILPIKNDNKGENYGSIY"
     gene            complement(5457..6407)
                     /locus_tag="RPH49_002139"
     CDS             complement(5457..6407)
                     /locus_tag="RPH49_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDY5125264.1"
                     /translation="MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLP
                     RLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPV
                     FSITFSLITLITVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTI
                     ANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLIT
                     YIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIEGQIMVM
                     ADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH"
     gene            complement(6556..7443)
                     /locus_tag="RPH49_002140"
     CDS             complement(6556..7443)
                     /locus_tag="RPH49_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015581799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDY5125265.1"
                     /translation="MKKSLIAFILIFMLVLSGCGMKDNHKQGSDDNGSSKSPYHRIVS
                     LMPSNTEILYELGLGKYIVGVSTVDDYPKDVKKGKKQFDALNLNKEELLKAKPDLILA
                     HESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEET
                     KDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGW
                     NPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSR
                     PGPRIDEGLKELRDAIYRK"
     gene            complement(7816..8451)
                     /locus_tag="RPH49_002141"
     CDS             complement(7816..8451)
                     /locus_tag="RPH49_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III domain-containing protein"
                     /protein_id="HDY5125266.1"
                     /translation="MLGTDELYKLLYRHMGPQNWWPADNDIEMMLGAILVQNTRWRNA
                     EIALNQIKEHTHFNPNHILELSIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQ
                     EINERYKGELRKELLSLKGIGSETADVLLVYIFGRIVFIPDSYTRKIYDKLGYENTKS
                     YDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK"
     gene            complement(8785..10446)
                     /locus_tag="RPH49_002142"
     CDS             complement(8785..10446)
                     /locus_tag="RPH49_002142"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDY5125267.1"
                     /translation="MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDY
                     ATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAII
                     PEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYN
                     VTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHP
                     EIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAK
                     MKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILI
                     DLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLR
                     EIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAK
                     EQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFH
                     KFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM"
     gene            complement(10443..10859)
                     /locus_tag="RPH49_002143"
     CDS             complement(10443..10859)
                     /locus_tag="RPH49_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDY5125268.1"
                     /translation="MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQI
                     EDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLEVKTLRILH
                     FVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE"
     gene            complement(10952..11059)
                     /locus_tag="RPH49_002144"
     CDS             complement(10952..11059)
                     /locus_tag="RPH49_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125269.1"
                     /translation="MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN"
     gene            complement(11136..12146)
                     /gene="adhP"
                     /locus_tag="RPH49_002145"
     CDS             complement(11136..12146)
                     /gene="adhP"
                     /locus_tag="RPH49_002145"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDY5125270.1"
                     /translation="MRAAVVTKDHKVSIEDKKIRALKPGEALVQTEYCGVCHTDLHVK
                     NADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETL
                     CRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVK
                     PGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDP
                     VAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVL
                     DGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVI
                     KF"
     gene            complement(12645..13166)
                     /locus_tag="RPH49_002146"
     CDS             complement(12645..13166)
                     /locus_tag="RPH49_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YwhD family protein"
                     /protein_id="HDY5125271.1"
                     /translation="MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFID
                     VANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAG
                     LTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGM
                     WKHSSDALHQAFN"
     gene            complement(13194..14489)
                     /locus_tag="RPH49_002147"
     CDS             complement(13194..14489)
                     /locus_tag="RPH49_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDY5125272.1"
                     /translation="MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLR
                     RIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALL
                     HDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHH
                     NKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMH
                     AVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFE
                     ETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISE
                     LQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIH
                     SITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN"
     gene            complement(14529..15005)
                     /locus_tag="RPH49_002148"
     CDS             complement(14529..15005)
                     /locus_tag="RPH49_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125273.1"
                     /translation="MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASY
                     NEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNE
                     GLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF"
     gene            complement(15174..15710)
                     /locus_tag="RPH49_002149"
     CDS             complement(15174..15710)
                     /locus_tag="RPH49_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin family protein"
                     /protein_id="HDY5125274.1"
                     /translation="MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDV
                     RHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRY
                     PNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDI
                     MKDNYALARATEWNSILQ"
BASE COUNT         5224 a         2943 c         2076 g         5844 t
ORIGIN      
        1 ttcttaagac ctaaattaat gttgtttttt aataatttat accaaattaa tagcaaaaat
       61 tatgttattc gtgctaatat ttcatagttg gttattcaat taattaaaaa taagtcaaaa
      121 tgcacaactt taattcattc attgagtcga gtttgaaaaa taaaggtgct ataacgtatg
      181 atcaattatc gtactttcta ttatttgtta cccgttatca atcggaataa cgtatagaca
      241 ctttaacgtg ctatagattg gttttaatca ctaaattagt gtgttttcct tatcattaaa
      301 actgcactgg gaattactaa attaaaaaaa ttataaaaat ttttcttttt tagtgataaa
      361 agttcgaaaa atgggtataa atattagaag aagttaactt gaaagcgtta agctatgaca
      421 atgaatcact ttagatacac attgaatatt gaaacattta attgcgctaa atcgtttcat
      481 aaaataaatt accttatact gacgattaaa ttaaggtaaa ttataaaaaa tgctgatatt
      541 tttgactaaa ccaaatgcta acccagaaat acaatcactg tgtctaatga ataatttgtt
      601 ttataaacac ttttttgttt acttctcatt tttaattagt tataattaac taaataatag
      661 agcattaaat atatttaata aaacttattt aatgcaaaat tatgactaac atatctataa
      721 taaataaaga ttagatatca atatattatc gggcaaatgt atcgagcaag atgcatcaaa
      781 tagggaggtt ttaaacatgg caattacaaa aatcaatgat tgctttgagt tgttatcaat
      841 ggtcacttat gctgacaaat taaaaagttt aattaaaaag gaattttcaa ttagctttga
      901 agaattcgct gtattgacat acatcagcga aaacaaagag aaagaatact atcttaaaga
      961 tattattaat catttaaact acaaacaacc acaagttgtt aaagcagtta aaattttatc
     1021 tcaagaagat tacttcgata aaaaacgtaa tgagcatgat gaaagaactg tattaattct
     1081 tgttaatgca caacaacgta aaaaaatcga atcattattg agtcgagtaa ataaacgaat
     1141 cactgaagca aacaacgaaa ttgaactata attttgttta gcgcaatttg gtgaagtttg
     1201 atagatgata cattctatta aacttccttt ttttatgctc tttttaccta attgttaaga
     1261 ggttttgcac taatggcact taatataagg aagatagccg cataacgagc agtatatatc
     1321 aaatacattt caaaaaaagc tgatttctat caaataatga atagtaatca gctttttcac
     1381 attgcctaag gactttatgc cctaggttta tatatcacat attatgatac gctttttaaa
     1441 aaatttaaat aataattcat aaatgcttct ggttcttcaa tatgcggtgc atgtcctgaa
     1501 tgttcgaaga tttttttcgt aacatttaaa aaatgcgctt ccaatttaaa atgattttta
     1561 tctttaatca aaggatcatg ttccccatta attaacaaag taggtacaca tgtacgtttt
     1621 tttaaataca taggttcatc tttatgcaaa attaatgaac gaattgccac cgcactatca
     1681 tcctcagact tagtgctata tattctttgt ttttgatacc atttcatcgt cttctcttga
     1741 tttctaaaca atttagaaaa taaaagaata tacgcttcag acttattaaa acccgctata
     1801 tcatcttgat attgtattaa caattgagta aagctgtgta ttaagtcatc tttcttcgat
     1861 gcaatggtag ttaatgattt tacacgataa gcatatttat ctgtaaataa cttagcaact
     1921 accccaccta aatcatgtcc tagaatatgt gcctcatgaa tatttaactt ctccattaga
     1981 atttttaaat cctcaacgtg atcgtttaaa tcgtatgatt cacttttaga agacttgcca
     2041 tgacctctta aatcgtaagt aagtacatta tatgatgatg ctagttgatg ttgcaaatct
     2101 tcaaatccag ctaaattacc atccaatcca tgaagtaata ttataggatc ccctttacct
     2161 tcaatttgat aagttaattg gatttgagga ttaattgtga ctttattcat tgtgacacct
     2221 ccctcaataa actatatacc caaccttcat tctatatacg cttccatttt ataaacaatt
     2281 tttttaaatt atttataaat taccaaaagt tattccaaca ataaaaaaac tattcatctc
     2341 aattaataca attaatcaag tgaatagttt tatcatattt ataatcttgt acgtgaagat
     2401 aatctaattg tgaaatatat aactagaact actaataata tccatataat taatgaaaaa
     2461 atctgggctg attgtggatt atgaatcatt gcatcgacgg ttttttgaca aaataataag
     2521 ccgattcccg aaaactcaag tcgcttataa aatatgccgg caattactaa aataatacca
     2581 atgaaaaaga aaaattgatg tccaaaattt gtaattggta taacgcccca agtaatatta
     2641 aatgcttgta atataattaa taacaaggat atgatagcga taattgtacc cataatcatt
     2701 tctattttat tactacgcaa gtaattcttt tgagacactc ttaggtatac aacaatagtc
     2761 attggaaaaa tcactaaaca ataaaataga ctcattccag taatagcttg aaactgaaca
     2821 tactgtttat catataaata ggatatgaga atgaaattta taataaagaa aataactgga
     2881 ttcatttgta aagcaaacaa attcctttga atcattaata tgatttgtgc tggagatttt
     2941 cttttatatt caatataatc ttgatctttc ttttcagaat tttttatatc agtaattact
     3001 ttctctttaa tatcatcaat caaatgcggt gataaacctt tatgattaaa gtaatcttct
     3061 atattttcta gtaaaatttt atcgttaata cgcattggta gtactccttt aaaatgaaac
     3121 atctttattt attgtattgg tttaatatcc ccttcgcaaa tcataaaaat taatattcac
     3181 tgtattatgc catgtaataa aataaccgac aagtattgcg atttaacttg tcggttaagc
     3241 acgattaatt taattattat ttttccaaat caatacgata taattttatg tttttatctt
     3301 ttggtgctga ggcaaattga taagtcgttt tgcctttttc aatatatcca aaattaccag
     3361 caactttgct atattccgta tgtgttactg ctttgccaac ataattttta acagcttgat
     3421 atgttggacc attagcatca ttatacatca ttgaaatatg agttacttta ccattgtttt
     3481 tcttaccatc agtagttact aataacatac cttttttagt atggaattcg taataatgtt
     3541 cagttccatc ttcattgtaa gaatacatcg gatttttgta cttagttaaa acatctttaa
     3601 tagattcgcc aattttcaca ttttctaatg actgatcacc cttaattaat tgtttaacag
     3661 tatcaataga gttgccactt gctgcttcgg cactagtgtt cactaagcct actcccatta
     3721 caacagaaca tgcaattata cttgccgtta gtagcttttt cataagcact ctctcctttt
     3781 atttatatcg tcttgtgctc acaaccatta tacaacaatc atttctaaaa caacagtcat
     3841 attacaatta tattacaaat aataattact acttttaaat ttcacttatc actaaaaatt
     3901 aaacatgctt ttcatcgtga tgtttgttga taaatgaagc tgtatcttcg acgaatcttt
     3961 cttgctcttc aacaaatggg aatgcacttg attcttgata tacttcaaag tccgcatttt
     4021 ggattaaatc agctacttct ttagcttcta atcttgttgt tctttcaccg aattctcctg
     4081 caataatttt tgtcggtact acgacatttc tataagtttg agaaatatca gcgtttttga
     4141 atacctcttt aactgcttga atttcttctt tagttgatat ttcatttgta tctacgacat
     4201 gtttgaggaa tcgattcatt tttctcggac gataatactt acgcttattt aaaaatttat
     4261 cttgtttttc aggatcccag tttcgaataa tatgggcata ttttctaaat aaacgttctt
     4321 ccggtaattc accttcaata gatgttggat ttaccaacgt aagtgatgat gtaaattcag
     4381 gataacgtac tgaaatatcc gcaccaatga ttccacccat ttcatggcat acaaatgcaa
     4441 cttcttcaat atataaatat ttaagtaatt caacaatgtc atcagaaaaa tcttttattt
     4501 caatgtgacg aggtttatca gaatagccat gtccacgtaa atcaattaac acaacttgaa
     4561 atgattttgc taattctgct gctaatttat taaacacaga ataattatca agtacagtat
     4621 gaatcaatac gataggatag ccttcaccta atgtactgta atgtatcgat gttccatctt
     4681 ttctagtaaa tagatccata attttctcct ttattatcat tttttattgg taaaatggtt
     4741 aataattctt ccactgttgt aattgtaaaa tcaacttctt cttcgagtgg ttcaatttca
     4801 gcatcttctt gtttatacca tacactaacc atgcccatag ctcgtgctgg agctacatca
     4861 tttaacgcat catcgccaac atacataatt tgctcaggta atacccctag ttgatcaatc
     4921 atatcttcaa aaattttagg atgtggttta cgaaaaccaa ctgtttctga tgttgataaa
     4981 taattaataa catgcatcaa accaagtgaa tgtaatcgaa attgtttaat cttagattta
     5041 ccatttgcga taacaccaat ttgaaagcct ttttgcgata gcttttctag tgtatacaaa
     5101 gtatcgtaat aaggaaatac ataacgataa aaatgcattt caaaatcatt aaataagtct
     5161 ttccaagtta acctatctac atggaaacgt ttaatgattt ctttatataa atcaggttta
     5221 tcattatctt catcgtcatc tagctcaata aatgcttttt taaaatctgc cagttgaaca
     5281 tgaattaagt agtcatgaaa tcgttcatat tgctcttcga taaatttctc tcgagattta
     5341 actctgtcca acaacgtacc ttctaaatca aatacaactg ctttaatttg attcaaatcc
     5401 atcgcttatg ccctctttat gtttatagtt atttttattt tagcaaatgt catgtgctag
     5461 tgtaaccgtt tcgactgaga tattagcatg taaaataaca ctggtatacc aattaatgca
     5521 ataataatgc ttgccggtat ttgtactggt gacagtatat ggctaccaat aaaatctgcc
     5581 ataaccatta tttgtccttc aattacaata ttcaaagcca attgtcttcc taatgattgt
     5641 ttccactgcc attttctaat gagttgtggt atcaccatac caatgaatcc aatgatgcca
     5701 acatatgcga catttatcgc cgttatcata gaagctatac ataacgcgat atatgtaatc
     5761 aattgaacat ttaagcctag tgactgactt tttagttctc ctaattgcaa taactttagt
     5821 tgattaagaa tgataaatat accaaacagt gcaatgataa atgtgattgc tattatggat
     5881 acatttgagt attctgcatc accaaaacca ccaaacagat aattggcaat tgtatttaat
     5941 ttgcgaggtt ttaataaaat caaaaaatat agaagtgaat tgaataacgc accaatcatt
     6001 aaaccactta atattaagat tctaactgga tagccttggc tcaataccga cgtaatgact
     6061 aatacagtta ttaatgttat caaactaaat gttattgaaa atacaggaat ccataacgtt
     6121 gttaaaccta aaaataatgc taatcctgaa ccaaatgtag cgccgcttgc caatcctaat
     6181 gtaaagctat ctgccaatgc attatttaaa actgtttgaa atataaggcc tgcaacagtt
     6241 aatatcatac ctgtcaacaa tgcttctaat aatctcggta atctaacatt gattagaata
     6301 gactggttaa atacatcatt gatatcgccc aactgccaaa atagatatat gctagttgtt
     6361 ataatcaata tgactatcca gctcaataat actttattaa atgtcatagc attctctttt
     6421 ctttcatcga taattacatt cattatagca atcacatact cgcgttgcta tcattcacta
     6481 aatatatttt aaaaacccct tatctcaaac atgtattttt ttacatgtag caataagggg
     6541 cataattaga atggtttatt ttctataaat tgcatctctt aattctttta atccttcatc
     6601 aatacgtgga cctggtcttg atacttcatc accatttaca acttcaatac gtgtattctt
     6661 gacagcatta attttattga atccacctct ttttttgatg atatccatat aatctgatct
     6721 tgtcttagct tccgtcgaaa ttaatatatc tgggttcttt ttaataatac tttccttcgt
     6781 tacagggttc caaccattaa tgtcactata cacattttgg gcttctaatt tttctaacat
     6841 atcattgaaa aatgtatgct tccctgctgt atatatttca ggctttgatg aaacctcaat
     6901 aaatactttt gattttttat gatgagcagg aattgaatct atgactttat cgatattatc
     6961 tttagtttcc tcaacaagtt gttcagcctg cttatcatga tgcgttaatt tcccaatttg
     7021 cttaaatgtg ttgtaagttt catcaattga ttgtgcatct ttaacatata ctactttgat
     7081 gccttgtttc tctaatgatg acaatacttt attagcagtt gccttttgcg actcatgcgc
     7141 aagaattaga tctggctttg cctttaaaag ttcctcttta tttagattca aagcatcaaa
     7201 ttgtttctta ccctttttca catcttttgg ataatcatca accgttgaaa caccaactat
     7261 gtatttacct aatcctaatt catataaaat ttcagtatta ctaggcatta acgaaacaat
     7321 tctatggtac ggcgatttag acgagccatt atcatcgcta ccttgtttat gattatcttt
     7381 cataccacag ccactcagga caagcataaa aatcaaaata aaagcaatta acgatttctt
     7441 cacattatca catctccttt ttaatcccac ttttcgcttt agcgattaga gggatttatg
     7501 cagttgtgcg gtagcatcca actgcgttcc tcttcatctt tagcgattag aggcttttat
     7561 gcagttgtgc cttagcatcc aactgcgttc ctcttcacct ttagtgatta gaggctttta
     7621 tgcagttgcg cggtagcatc caactgcgtt cctcttcacc tttagcgatt agagggattt
     7681 atgcagttgt gcccaagcat ccaactgttt ttcactttat atgcttctat ttattatata
     7741 agtccacata ctaaaagaaa atagtaaatt attttttata tttcatataa actcatctat
     7801 ctaacttcac agcgtttact ttttaaagta aggttctaaa aaatcataat tctttatatc
     7861 tttgtctcta aagtaatgtt taccaaatac atctaacaga gcatgaaatt cattagcatc
     7921 ttgatttgta aaatgatttg gtaatgtgac tacttttttt aattgatcat aacttttagt
     7981 gttttcatat cctaacttat catatatttt tcttgtatag ctatctggaa taaatacaat
     8041 gcgtccgaat atataaacaa gtaagacatc tgctgtttca cttccaatac ctttcaaaga
     8101 taataattct tttcttaatt cacctttata tcgctcatta atctcttgat aattgaaatg
     8161 atgtcgtgct aaccatgtta ataatgtttt aatcgtcagt gatttacttt tataaaaacc
     8221 acttgaatgt atcaatgatt gtaacgtttc aatagatagt tctaatatat gatttggatt
     8281 aaaatgcgtg tgttctttaa tctgattcaa tgcaatttct gcatttcgcc atctagtatt
     8341 ttgaactaaa attgcaccta acatcatttc aatgtcatta tcagcaggcc accaattttg
     8401 cggtcccata tgcctatata acaatttata caattcatca gttcctaaca tttacatcct
     8461 ccttttagag ggagtgggac agaaatgata ttatcgtaaa atttatttcg tcgtcccacc
     8521 ccggcaaggt tgactagaat tgaaaaaagc ttgttacaag cgaattttcg ttcagtcaac
     8581 tactgccatt ataactttgt agagcataga acattaattt atgtctcagg ctctcttatg
     8641 cagttgtgcg caagcaagcc aactgcgttc tcttaacctt attcacatac taagcattcc
     8701 ccaatatgtc acatacctaa ttaaaaacac tccaacacaa agtatctttc gagaaactct
     8761 acgttggagt gtatataaat gttcttacat tgattcaggt gcgcttacac cgaccattgc
     8821 caatgcattt ttcaatgtaa ttctaaccgc ttcaatcata gcaacatgtg cttttgtttt
     8881 ttcaatatca tctgttaaca ctttttcagc attatagaat ttatggaaat gagaagctaa
     8941 atcttgaata taattagtaa ttctatgtgc cgatctatgc tcagcagcac tttcaattgt
     9001 aggttcgaaa tcagctactt ttttcaacaa ttcaatcgct ttttcattag taatcgttgt
     9061 aaaatcattc gcagcagtca cttcaatacc ttgctctttt gcttgtttta aaattgaaca
     9121 aatacgtgcg tgagcatatt gagcataata aactgggtta tcttgagatt gctctttcgc
     9181 taattccata tcaaaatcaa agtgactatc aggactacgc atagttaaga aataacgtgc
     9241 agcgtcaacg ccaacttcgt ccataatttc tcttaatgta atggcattac cagtacgttt
     9301 actcatcttc acttctttac cattttccat taaacgaacc atttgcatga tttgaatttc
     9361 taaacgatta ctatctacac caaacgtttc aagagatgct ttcaaacgat taatataacc
     9421 atgatgatca gcaccaaata aatcgattaa aatgtcatta ccacgtttaa ctttatcgaa
     9481 gtggtacgca atatctggta agaaatacgt atatgtaccg tcatttttaa ttaatactct
     9541 gtctttgtcg tctttaaaat cagttgtacg taaccatgta gcgccatcag cttcatacgt
     9601 ataacctaat tctttcattt ttgctaaaac ttcaagaatt tcgccttttt catataaaga
     9661 tgtttcacta aaccaattat caaaatgcgt attgaactct gctaaatcat ttttcaattt
     9721 agccatttcg tattctacgc ctaattttct aaattctttc aaacgtgctt cttcagaata
     9781 atctttaatt tcagggtgtt tctctgctaa atctttacct atttcaataa tatcttttcc
     9841 attatagcca tcttctggca ttgaataact attgtcacct aaagcttcaa agaaacgtgt
     9901 ttcaatcgaa cgcgctaagt tagtaatttg attaccagca tcattaatat aatattcacg
     9961 tgttacatta tagccagctg cagttaaaat attagctaaa gcatcaccaa ctgctgcatt
    10021 tctagcatga ccaatatgta aatctcctgt agggttagct gaaacatact caagcaatac
    10081 attttgccct tttgattcat ttacatgtcc aaattgatca cctttttcaa ttgcttcagg
    10141 aataattgct gttaaatact gattatctaa gtaaaaatta atgaatcctg gaccagcaat
    10201 gtcaatttgt tttacatgtg ctttttcagt atctaagtta tcaacaatcg cttgagcaat
    10261 ttcacgagga ttacgctttg caatcttagt cagtaccatc gcaatattag tagcataatc
    10321 tccatttttt gtatctttag gaacttcaat tttaatatca ggaatctcat ctgctaatcc
    10381 tgctttgtta atacttgctg caatttcttc tactaatgtt tgtttcactt gatcaataat
    10441 attcattcgc ctatctcctt atagttaatt tcatattgat aagaacccat tttttcatta
    10501 tcttgatata attcataatg aatctttagc ttgccaccgt ctccacttac gaaatgtaaa
    10561 atgcgtaatg ttttaacttc tagtggaatt cgtccagccg atatatcgta aaaagttgtt
    10621 gtcgtttgtc cttcaacaaa atgcaaattc atattaatgt cgcctttacg aatcaactta
    10681 acgctatcat catccacttt tattgtaaca ttaactgttg catcctcaat ttgttctaca
    10741 taccgaataa agttagattg cctttgttgc caagttcctt cagtagtaaa ttcaaatttt
    10801 tctttttcgt tgtgctgttt caacacttgc tttgtttgaa tacttacttt tttatccaat
    10861 ttactactca ccttaatctt cgcataatag aaatattata gcataaaata aggtcatctt
    10921 gttatgcctt cttaaagcta aataggttca attaattaac aattccatac ttaatcaacg
    10981 cttcatatat gtaagccatt ttataaaata caaacaacac ctcaaaacca aaaaacacga
    11041 gattttcact atctttcatg aaaacctcgt gtttgattat aatgatagtg ttcagagcac
    11101 taccttcttc atctatattt aatcaattaa tatttttaaa atttaataac cattctacca
    11161 gttatagtac cattttccat ttcttcaaaa atatcattga tttcttctaa ttttcttaat
    11221 tgaactttag gtgttacttt attttcagca gcaaattcaa acgcttcacg taagtcttgt
    11281 cttgtaccaa caagtgaacc tactacttca ataccgtcaa gcactaatct tgggatatct
    11341 aagttcattt tatcaacagg taaaccaaca gcaacaactc ttgcaccagc ttttacaaca
    11401 tcaaccgctt ggttaaatgg cgtcttagca actgaagtta ccactgttgc atctaatcct
    11461 ttgttatcag ttaatttcat aacttctgca actggatcaa catctttaga attaataata
    11521 gcatcagcac ctaattcttt cgcgaatgct aatttatcat cattgatgtc gaaggcaaca
    11581 attttagccc ccataacgtt tttagcatat tgtaaagcta ggttacctaa accacctata
    11641 ccaaaaacac ctaaccattg tccaggtttt acattactta cttttacagc tttataagtt
    11701 gtcacacctg cgcatgtaat agaagacgct gctgctggat ctaatttttc aggtactttc
    11761 acagcatagt ctgcagtaac aataacttgt tcagccattg caccatctac tgtataacca
    11821 gcatttttca cactacggca aagtgtttca cgacctgttg tacaatattc acatcttcca
    11881 cagctttcga acatccaagc gatagacaca cggtctccaa tttttaatga ttctacatct
    11941 tccgcaactt cgatgacttt accaatacct tcatgaccta aagtaacgcc tgtaacatca
    12001 ccaaaatcag cattcttaac atgtaaatcg gtatgacaaa cgccacaata ttccgtttgt
    12061 accaacgctt caccaggttt taaagctctt atctttttgt cctcaatact tactttgtga
    12121 tctttcgtta caactgctgc tctcataata atgtcctcct tatagtcact ccagtatgta
    12181 tgatattaat tggctattac tttcaaaaaa gaaaacgaat aattatagat gtaattttta
    12241 tttgtaatag acgccagatt aaaacatact actgtgacct tgtttttagt tagatatcaa
    12301 ccgttaactt ttaacgtttc cctagttaat atgttaaaag aaatgacata atcgatatgc
    12361 taacgtgtaa tttttacttc acatatattt atttaaagat aatttataat actcttatct
    12421 tcactcttat tataatgtga attaattcac aaagtatata gctatgatca aaaaaatgtg
    12481 tcagttattc aaatttttta ttaactacag attaatttaa tttcaaaaaa attaaaaaaa
    12541 ctcccaatca atctaagact ttattttcac ctcaagattt acgtcgtcat tgagaaatga
    12601 atcatatctt tatagattaa ttgggaaatt ttagtttcta atatttaatt aaatgcttga
    12661 tgtaaagcat cagaagaatg cttccacata ccttcatcat ggttcattaa aaagtctttt
    12721 aaaatagctt tattctcgtc accaatttga tcaatgataa tatgatgttt cattgattta
    12781 tccatcatat taacatgttc aggcatactt ttataaccac gacgaattgc tttattcact
    12841 aataaatagc acgctgttaa accagcataa tatggtcctt gttcattacg ttctgttgtt
    12901 acccaacaca accaatattc tttagcttca tcgccttcaa cagcagcttt atcagtaatc
    12961 catttcacgc ctttttcaac tttggcgcga gcatgcatgc ctccaatatc aataaatgct
    13021 tctttgttag caacatcgat aaaaactggt gcaatattgt ctaagctaat tgaaccaata
    13081 tttgtacctt tatgaccatc tagagggtca ttttttatga tattaaaatt aaagcctttt
    13141 ttctcagaca atgatataac ctccatattt aacgataaca attttagccc tttttaatta
    13201 agctcattaa tcaaattttc aatagcttct ctaattgtct tatctttaat ctttgcaacc
    13261 atttctctag gataatataa tttatagtct tggcgattaa tgcctgtaat actatgaatg
    13321 actaaagatt gattgcttat ttctctaatc gtaccatctt gtcttaataa atgaatcggt
    13381 ttgcgatttg acccaggtcg atcatagtca tatggcaaat ccgaaaatgc ttcactcaca
    13441 aaataataat ctggattaat accacctgct tcaaacagtt cttgcagttc tgatattgta
    13501 ataattgagc catcaaatgg aatatattta aataagtctc gattaataaa tcgacttgct
    13561 aaatcactta aaatagcatc atcttctttt gtccattttt ccaaataata cgtaactacc
    13621 gcttcatcga gttcaacata ttgttcaatc gtaactgtct cttcaaaaaa tggaataaaa
    13681 tcatgtggat gcaacttaaa ttcatagcct tcattataaa gctgttttgc gcgtttcaaa
    13741 caattattaa gcagcacttc tccaccacga ctaactgggt ggaaataaat ttgccaatac
    13801 atttgataac gactcataat aaagttttca actgcatgca taccactttc tttaattagt
    13861 acttcatctt tagaaggtcg cattaatctt aaaatacgtt ccatatcaaa agcaccatat
    13921 gatacacctg tgaaatacgc atcacgttgt aaataatcca ttctatccgc atcgatttgt
    13981 gaagaaatca tcgaaatgac caatttatta tgatgcgttt tattaattac ttccgcaact
    14041 tctcttggaa actcaggcgc cactttacgt aatacagcat tcacctcagt atctccagta
    14101 ataatcgctt gtgtgtatgc ttcatggtct gtattaaata ttttttcaaa actatgtgaa
    14161 aatggaccat gtcctaaatc atgtaataat gcagcacata atgccaacgg tctatcttta
    14221 ttgtcccatg catcatgacc aataaatgac tcatcaatta atcgtctaac tatttcatac
    14281 acacctaaag aatgtccaaa gcgactatgt tctgctgtgt gaaaagatag gtacagtgtt
    14341 cctagttgtc taattcgacg taacctttgg aattccttag ttttaattaa atcccatatc
    14401 aattgatctt caacatgaat atatcgatgt atcgggtctt taaaaacttt ttcttctact
    14461 aattttaaat ctacatatgc gttagtcatt attcccctcc ttttcgttta atataatatt
    14521 taatttactt aaaatgcttt gtacataagt gctaagtcta acttttcgcc atacatttct
    14581 ggctcataag agcgtaagat tgtaaaacct tgctctttat agtaagctac tgcttcttca
    14641 tttttattat ctacttctaa gtaaacacct tcaaatttat cttcaaaacg tgataatcct
    14701 tcatttaaca atgctgtacc ataacctgta tgttgcgatt ctggtttaac ataatgagct
    14761 gataaatata attcttcacc gtaaataaag ttagcaaagc caacgatgtc attaccttct
    14821 tcaacgacta agaataattg ttcttgaagt cttttcttta aatgatgttc attatatgaa
    14881 gcttctaaca agtgattaac tgttgtcgca gcgtatatat ttaagtatgt attaaaccaa
    14941 gctttagttg cgacatctct aatttgaaca acatcttttt cagttgcttg tcttaccttg
    15001 aacatgactt tctcccctta ttaacaagtt ttaataacgg cattatacca caacttgctc
    15061 aatacttaat aaacaatgat tgtctattca atttatatat ttatattttc cgttaaaatt
    15121 aaaaataaaa aataacgaag caaaaaatca cttcgtttag tatgaggtat gtcttattgc
    15181 aatatactat tccactcagt tgcacgtgct aaggcatagt tgtctttcat gatgtcacca
    15241 ggcttttcag cagttccaat aatataacca tttaaagtgg cacctaaaaa gtctaaacta
    15301 tatttcattt gcgtaattgc tggcttcgct tttatttttg gacaatctcc accaactaaa
    15361 ataactctaa aatccttttc ggccatttgt gccttaaaat taggatatcg tttatcttgt
    15421 aatgtttctg accaatgttc gataaatgct ttcaatggtg ctgaaatgct ataccaatac
    15481 actggtgatg caaaaataat tgtatcacta gccaatattt tatctagaat cggcaaatag
    15541 tcatcgtcat atgaagtaat agtctctgct gtatgtctca cgtcacgtat cggtttaaac
    15601 tgatgttgtg tcacgtcaat ccattgatac tctaaatctt gcaaagcgaa ttttgttaat
    15661 tgtgcagtat taccgtttgg tctgctccca ccaaacaaaa cagtaatcat tttagcctaa
    15721 cctcactttt gattaataaa tatctgtgtt tttcgttacc taattatact atcataagct
    15781 ttgcctaccg aatagtaaaa cgcttacaac ttttatataa atttgacgaa atttcgtcat
    15841 ccttatataa cgtcgtttgt gatgggagtg ggacagaaat gatattttcg caaaatttat
    15901 ttcgtcgtcc cccccaactt gcacattatt gtaagctgtc ttttcgccag cttctatgtt
    15961 ggggcccgcc aacttacatt gcctgtagaa tttctttttg aaattctctg tgttggggcc
    16021 cacaccccaa cttgcattgc ctgtagaatt tcttttcgaa attctctgtg ttggggcccc
    16081 tgactag
//
LOCUS       DAPSKH010000060        15942 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPSKH010000060 DAPSKH010000000
VERSION     DAPSKH010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15942)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15942)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15942
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.060"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(56..889)
                     /locus_tag="RPH49_002150"
     CDS             complement(56..889)
                     /locus_tag="RPH49_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDY5125275.1"
                     /translation="MEVKTFYNGNTMPKIGLGTFRVENDENCMESVKYAIEQGYRSID
                     TAKVYGNEEQVGAGIRAGLESTGIAREDLFITSKLYFEDFGRENVAAAYEASLSRLGL
                     KYLDLYLVHWPGTNEAVMVDTWKGMEDLYKNNKVKNIGVSNFEPEHLEALLAQVSIKP
                     VINQVEYHPYLTQHKLKLYLAAQHIVMESWSPLMNAQILNDEAIKDIAQELGKSPAQV
                     VLRWNVQHGVVTIPKSVTPNRISENFQIFDFELSDEQMTRIDGLNQDKRIGPDPKTFE
                     G"
     gene            complement(1106..2014)
                     /locus_tag="RPH49_002151"
     CDS             complement(1106..2014)
                     /locus_tag="RPH49_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein"
                     /protein_id="HDY5125276.1"
                     /translation="MDLSSPIVIGLIIAVVIALIFFVLFLVALGSKKKVKRQTEEKYE
                     QQEQNIKKSHEEALEKERIQNKKTITKQQEDYNHMVSTKDREIDALKLFSKNHSEYVT
                     DMRLIGIRERLVKEKRIRPEDMHIMANIFLPKDGFNNIERISHIVLTRTGLYIIDSQL
                     LKGHVYNGISGGQFKDLPPMEQVFDTLDLDKSRPQTIVMDQNDDKRSLSFVNYSDQIE
                     AIKQLAEDLQKELGAKYTPTSILYFNPKNEGDVTISNYNQNSAVKVLVGAEQLDEFFN
                     KFVFHGRIQYNVEDLQQMMDKIESFN"
     gene            complement(2139..3332)
                     /locus_tag="RPH49_002152"
     CDS             complement(2139..3332)
                     /locus_tag="RPH49_002152"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDY5125277.1"
                     /translation="MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVAC
                     ETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQS
                     PDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKR
                     LSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHAEDVTLEQIQEDIKA
                     HVIYQTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCF
                     SGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKV
                     SEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEEL
                     KDAVK"
     regulatory      complement(3438..3548)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00162"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF00162"
     gene            3703..5295
                     /gene="pckA"
                     /locus_tag="RPH49_002153"
     CDS             3703..5295
                     /gene="pckA"
                     /locus_tag="RPH49_002153"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDY5125278.1"
                     /translation="MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTE
                     LGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGDINQPIDEETFLKLYHKVLDYLDK
                     KDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVS
                     APHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMS
                     MHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAK
                     AINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVV
                     PSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSF
                     STCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMV
                     NQAISGKLKNAEYTKDSTFGLSIPVEIEDVPKTILNPINAWSDKEKYKAQAEDLIQRF
                     EKNFEKFGEKVEHIAEKGSFNK"
     gene            complement(5673..6419)
                     /locus_tag="RPH49_002154"
     CDS             complement(5673..6419)
                     /locus_tag="RPH49_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S9 family peptidase"
                     /protein_id="HDY5125279.1"
                     /translation="MPIESFTHQLEEITYLSDDLQVKALMMTPHHEVKRIVVYLRGGK
                     GQVGRVRAGRLMQFSDSQTLVIGPYYRGNNGSEGKDEFYRGDLNDVTELLRLLHDKYP
                     QAFIHMVGFSRGGLQGLLTFQDLPVNSYIIWGGVSDIDLMYEERVDLRGMLRRMIGHP
                     KKDRAAYEARQAIPNINENSPPILIVHGGKDQQVGIHHAYYLADQLELKGATHETFYQ
                     MAEGHVPRPPAMVETLTYIKEFMNQVELHS"
     gene            complement(6424..6897)
                     /gene="ytkD"
                     /locus_tag="RPH49_002155"
     CDS             complement(6424..6897)
                     /gene="ytkD"
                     /locus_tag="RPH49_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase YtkD"
                     /protein_id="HDY5125280.1"
                     /translation="MKFRDKDNRQVNLTFKKDNEVADGNHVLAIPTFKNQLLFTKHNL
                     RGIEFPGGKRERGESSAEAVTRELYEETGAKVKNIHYIAQYTIETHDQTDFVKDVYFI
                     EVESLVSKNDYLETAGPVLFNCINDIELTQRSFLLQDSTILKCVERVQSLGFYQT"
     gene            6963..7220
                     /gene="yidD"
                     /locus_tag="RPH49_002156"
     CDS             6963..7220
                     /gene="yidD"
                     /locus_tag="RPH49_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDY5125281.1"
                     /translation="MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAF
                     KGLYLGIRRILKCHPLHKGGFDPVPLKKDKSESKHSHKHNH"
     gene            complement(7217..8218)
                     /gene="menC"
                     /locus_tag="RPH49_002157"
     CDS             complement(7217..8218)
                     /gene="menC"
                     /locus_tag="RPH49_002157"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDY5125282.1"
                     /translation="MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAY
                     FGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARAT
                     IVMALYQIFHVLPSFSVAYGATVSGLSNKQLESLKATKPARIKLKWTPQIMHQIRVLR
                     ELEFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDDVVDGTIPPIAL
                     DEKATSLLDIINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYG
                     LSRYFTAMLARKGDYPGDVTPAGYYFEQDVVAHSGILKEGRLEFRPPLVDITQLQPY"
     gene            complement(8223..9701)
                     /gene="menE"
                     /locus_tag="RPH49_002158"
     CDS             complement(8223..9701)
                     /gene="menE"
                     /locus_tag="RPH49_002158"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDY5125283.1"
                     /translation="MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAY
                     QQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMKSIDVQLIFCTLP
                     LELRGFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNL
                     DDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLS
                     VLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQK
                     ILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANV
                     DVKIKNPNKEGHGELMIKGANVMNGYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIY
                     DRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISK
                     AQLIAYLSQHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG"
     gene            complement(9860..10315)
                     /locus_tag="RPH49_002159"
     CDS             complement(9860..10315)
                     /locus_tag="RPH49_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4909 domain-containing protein"
                     /protein_id="HDY5125284.1"
                     /translation="MKICLMLYLLIFLSSCGTNNKIVGQRFEIQQHNETIGSIYFSAD
                     YAHIRGIEKGTAKYFIDKVGSKRYLFIEYIPDNVLNCKPDFWKTLKYKKDKVTYYVYL
                     IENLDDEVFHLSALQDMNRIPIDIADDVATMGKSPHQNDRMTLKLNKNN"
     gene            10617..11267
                     /locus_tag="RPH49_002160"
     CDS             10617..11267
                     /locus_tag="RPH49_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excalibur calcium-binding domain-containing
                     protein"
                     /protein_id="HDY5125285.1"
                     /translation="MKITYKYRGDLPLNTENNKNQNQSVKNSERRGMLKGCGGCLISF
                     ILLIILLSACSMMFSNNDNPTSNQSSKTQLTQKDENKNEDKPEEKSESETDKDLQSTE
                     EVPANENTENNQHEIDEITTKDQSDDDINTPNVAEDKSQDDLKDDLKEKQQSSNHHQS
                     TQPKTSPSTETNTQQSFANCKQLRQVYPNGVTADHPAYRPHLDRDKDKRACEPDKY"
     gene            11348..12343
                     /locus_tag="RPH49_002161"
     CDS             11348..12343
                     /locus_tag="RPH49_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDY5125286.1"
                     /translation="MSNQFKSEEERRQWEQFQAFQNQQNQQNQQYGQKKSKKGWFWGC
                     GGCLVLFILIIIGISACTAGITGNLGGNSSKETNKTHKIGETVKNGDLEVTVNSVETM
                     KSVGPSLAPTNAKGTFVVADVTIKNKGKEALTIDSSMFKLKSGDKTFEADNTGSMSAN
                     QSDNGSIENSFFLQRINPDSTAQGKIVFDVSENIANAKDKKLEVISSLFSVKKITFDL
                     SEAKKTSKAKKDKQDTEVAVASSNSDNISYEASATTPATTSSADTDSEDSEKSSKDED
                     KQNASKSDKSSVEKSESNEETAPVEPMRQSKPTTSEAPPSQNIHNEDSMYDASTE"
     gene            12419..13045
                     /locus_tag="RPH49_002162"
     CDS             12419..13045
                     /locus_tag="RPH49_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125287.1"
                     /translation="MKFKAIVAITLSLSLLTACGANQHKENNSKSNNTNKKTQQTDNT
                     TKSNTDKQMTPQEAEDIVRNDYKARGANENQTLNYKTNLERSNEHEYYVEHLVRDAVG
                     TPLKRCAIVNRHNGTIINIFDDMSEKDKEEFEAFKKRSPKYNPGMSDQAEMDNESEDI
                     QHHDIDNNKAIQNDIPDQKVDDKSDKNAVNKEEQHDNGTNNSEETKVK"
     gene            13086..13427
                     /locus_tag="RPH49_002163"
     CDS             13086..13427
                     /locus_tag="RPH49_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3969 family protein"
                     /protein_id="HDY5125288.1"
                     /translation="MITFENIQQLEKYTLMTMHGLFNQLKLGIISIDNAEHTFFTPYM
                     MESLSSLGVKPDIIDLIHKGTELEDFAAFNLSIDDTVTVCLQRTEELLKQYKNVEFND
                     KILINWRVIQK"
     gene            13528..14100
                     /locus_tag="RPH49_002164"
     CDS             13528..14100
                     /locus_tag="RPH49_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125289.1"
                     /translation="MEKNEYTAKYNEYNQLLDATYSQAVAYLLNKYGAVTDDYYKEKS
                     YTRFLNGEIKSITKGKYTRASEGLYCHHISEDKFQNLSDLRFISEFKYSYNYQKKENL
                     VYCDLIEHLILHAIITKESDGQFGAAGLCQMIKPTVIDWYISEYNPKPAWMQATKARA
                     YLPRILVEKLLIKIDDMLEGIEIYDFLESR"
     gene            complement(14297..14866)
                     /locus_tag="RPH49_002165"
     CDS             complement(14297..14866)
                     /locus_tag="RPH49_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDY5125290.1"
                     /translation="MKVIEKVHYEDILESKIVRLFQAFIKDKMDQLFITSEHFAIDID
                     KLLFQLNLNVKYIKMEGNTSGYLSGRTIYINNNHSINNTRFAIARELGRYLFKNSDLM
                     RDNNDNSLKNLHEMIYESDVNQFSVDLLMPKKQIEALVYNFYEVNNINLSSGLSEKER
                     NKLLNLISTKLEVSKVAAGLRLYNLGIHI"
     gene            complement(15052..15237)
                     /locus_tag="RPH49_002166"
     CDS             complement(15052..15237)
                     /locus_tag="RPH49_002166"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125291.1"
                     /translation="MKQISIGYEKIYEDRIFHSHFLKEQEVKNWKTVDQIIKNEHLVK
                     SDYEAEPPLFFFSGSLD"
     gene            complement(15239..15415)
                     /locus_tag="RPH49_002167"
     CDS             complement(15239..15415)
                     /locus_tag="RPH49_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125292.1"
                     /translation="MDRLKYSLKVGILALLLFCTLNYLVPMQSNAFSIIIYSAIFAVL
                     LMLLVYIFLGILKK"
     gene            complement(15426..15809)
                     /locus_tag="RPH49_002168"
     CDS             complement(15426..15809)
                     /locus_tag="RPH49_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125293.1"
                     /translation="MSNQNLFDELEKKGYKLEDIFTKEEIKKFKAEDQLRAGKTQYVE
                     TGKDTATLYLSSAYTKTIAALGAGTISVISALTGGLVGAGVGSFLGSIAASNIDTSKR
                     IYLKLKTKKNAAGEYVLIGEKWGYQ"
BASE COUNT         5376 a         2920 c         2387 g         5259 t
ORIGIN      
        1 atgtcccagc ctgtgacaat tcatctaacc ttttcatcag ttgagcgatt ttaacctagc
       61 cttcaaaagt ttttggatca ggtccaattc tcttatcttg atttaaacca tcaattcgtg
      121 tcatttgttc atctgataat tcgaaatcaa atatttggaa gttttcagag attctgtttg
      181 gtgttaccga tttagggatt gtaaccacac catgctgcac attccatctt aaaacaactt
      241 gggcaggtga ctttcctaat tcttgagcaa tgtctttaat tgcctcatca tttaaaattt
      301 gtgcattcat caatggtgac caagattcca tcacgatatg ttgtgctgcc aaatataatt
      361 tcaatttatg ttgcgttaaa tatggatgat attcaacctg attaattaca ggtttaattg
      421 acacttgtgc caacaaagct tccaaatgtt caggttcaaa attgctgaca cctatatttt
      481 taactttatt atttttatat aaatcttcca tacctttcca tgtatcaacc attacggctt
      541 cgttcgtacc tggccaatgt actagataca aatctaagta ttttaaacct aatctagata
      601 aactagcttc gtaagcagct gctacatttt cacgaccaaa atcctcaaaa tataattttg
      661 aagtaataaa taagtcttct ctagcaattc cagttgattc taatccggca cgaatgccag
      721 cacctacttg ttcttcattc ccataaactt ttgcggtatc aatactacga tatccttgtt
      781 caatggcata cttaacactt tccatgcaat tttcatcatt ttccacacga aatgtcccta
      841 aaccaatttt tggcatcgtg tttccattat aaaatgtttt aacctccata aatatcgcct
      901 cacctttttg atgtattata ccctgttatc ataacaaatc tgagttgaat acatgagaaa
      961 aaacacttaa cttatagcaa tcaatcacta aaatgctagt aatatctttc aaatattaat
     1021 caaaatgtaa aagcaattct gtttaattta tgacaaacta aaaaagccga agtaacaaca
     1081 tatagtcatc acttcagcct aacatttaat tgaatgattc aattttatcc atcatttgtt
     1141 gtaagtcttc cacgttgtat tgaatacgac catggaatac aaatttgtta aagaactcgt
     1201 ctaattgttc agcaccgaca agcactttga cagcactatt ttgattataa tttgaaatcg
     1261 ttacatcgcc ttcattttta ggattaaagt ataaaattga agttggcgta tatttggcac
     1321 ctaattcttt ttgtaaatct tcagccaatt gtttaatcgc ctcaatttga tctgaataat
     1381 ttacaaatga taatgaacgt ttgtcatcat tttgatccat cacaatagtt tgcggtctag
     1441 atttatctaa atctaatgta tcaaatactt gttccattgg tggtaaatct ttaaattgac
     1501 cgccacttat accattataa acatgacctt ttaacaattg agaatcaatg atataaagtc
     1561 cagttcttgt taagactata tgactaatac gttcaatatt attaaagcca tccttcggta
     1621 aaaagatatt tgccataatg tgcatatctt ctggtcgaat tcgtttttct ttaactaatc
     1681 tttcacgaat accaattaat ctcatgtccg ttacatattc actatgattt ttcgagaaca
     1741 attttaatgc gtcaatctca cgatcttttg tactaaccat gtgattataa tcttcttgtt
     1801 gttttgtaat tgtcttttta ttttgaatac gctctttctc taaagcttct tcatgagact
     1861 ttttaatgtt ttgttcttgt tgttcatact tttcttctgt ttgtcgctta acttttttct
     1921 tactacctaa ggcaactaag aaaaggacaa aaaagattaa tgcaatgact actgcaataa
     1981 tgagtccaat gactatcggt gaagataaat ccatcacaac aacgctcctt tttaatatat
     2041 gaataacttt aattataata gaaaagctaa agattttcga tacatattat catttatata
     2101 ccgaaaatct tttatttagc tatattcaat tcatcttatt attttactgc gtcttttaat
     2161 tcttccactt tgtctaattt ttcccatggg aataatacat ctgtacgtcc aaaatgacca
     2221 taagcagcag tttgtttgta aattggttgt ttcaaatcaa gcattttaat aataccagca
     2281 ggtcttaggt caaagtgttt tctaactgct tcaacaagtt gcccttcaga aactttacct
     2341 gttccaaatg tatcaattgc aattgacact ggttctgcaa caccaatcgc atatgccaat
     2401 tgtacttcac attgatctgc taaacctgct gcaacaatat ttttagccac ataacgtgca
     2461 gcgtatgcag ctgaacggtc tacttttgta ggatccttac cactgaagca tccgccacca
     2521 tgacgtgcat agccaccgta cgtatcaaca atgattttac gtcctgttaa tcctgcatca
     2581 ccttgaggtc caccgattac aaagcgtcct gtaggattga tgtagaattt agtttgttca
     2641 ttaatcaagt tttctggaac agtttgataa atgacatgag ctttaatgtc ttcttgaatt
     2701 tgttcaagtg tcacatcctc agcatgttgt gttgatacga caatcgtatc aatacgtact
     2761 gggttatcat tttcatcata ttcaacagtg acctgaactt taccgtctgg tcgtaaataa
     2821 tttaatgtac catctttacg cacatctgat aaacgttttg ccaattgatg tgataaataa
     2881 attgctagag gcatatacgt ttctgtttca ttcgttgcgt aaccaaacat taaaccttgg
     2941 tctcctgcac ctgttgcttc aatttcttct tcgctatctt tatcacgata ctctaatgct
     3001 ttgtccacgc cttgtgcaat gtcaggtgat tgttcatcaa tcgcagttaa aattgccatt
     3061 gtttcataat catagccata ttttgctctt gtgtatccaa tttctttgat tgtttctcta
     3121 acaactttcg gaatatcaac atatgttgtt gtagaaattt cgccggcgat caatgccata
     3181 cctgttgtaa cagttgtttc acaggctaca cgtgcatttg ggtcgtcttt taaaatagca
     3241 tctaatattg catctgacac ttggtcagcg attttatctg ggtgtccttc tgtaacagac
     3301 tctgaagtaa ataatcgttt gttatttaac atagtttgct cctttaaatt tatattacga
     3361 aaattctctc tctgtgagct aaataaaaaa gaccttctaa ctattaatat agagagaagg
     3421 cctaatacgt ccattcgctc ttatcgttca gacctatttg tctgcaaacg gtttggcacc
     3481 tttcttttat aaaaaagagg ttgctgggtt tcattgggtc catgtccctc caccactcag
     3541 gataagagaa tccgttaaaa ataatagtac ctaattaatg aattaatgtc aatttttcat
     3601 aaataaattt ccagtaaaat attgtagatt aattatgtta atgtgttata ctaattaaat
     3661 gtaaaggctt acatttaaat tatcgctttg gagggattta ggatgtcagt agacacatac
     3721 actgaaacaa ctaaaattga caaattactg aaaaaaccaa cgtcacattt tcaactttcg
     3781 acgacacaac tttataataa aattttagac aacaatgaag gtgtattaac agaacttggt
     3841 gctgttaatg ctagcactgg taaatatact ggtcgttcac ctaaagacaa attttttgtc
     3901 tcagaacctt catatcgaga taacatcgat tggggagata ttaatcaacc gattgatgaa
     3961 gaaactttct tgaagttata ccacaaagta ttagactatt tagataaaaa agatgaatta
     4021 tacgtattta aaggctacgc tggtagcgat aaagatacaa tgttaaaact tacagtcatc
     4081 aatgaattag catggcataa tttatttgct aaaaatatgt ttattagacc tgaatcaaaa
     4141 gaagaagcta caaagattaa acctaacttc actatcgttt ctgccccaca ttttaaagca
     4201 gatccagaag ttgatggtac taaatctgaa acctttgtca ttatttcatt taaacacaaa
     4261 gtcattttaa tcggcggtac tgaatacgct ggtgaaatga aaaaaggtat cttctctgta
     4321 atgaattatc tcttaccgat gcaagatatt atgagcatgc attgctcagc aaacgttggt
     4381 gaaaaaggcg atgttgcatt attctttggt ctatctggca ctggtaaaac aaccctatca
     4441 gcagatccac accgtaaact aatcggtgat gatgaacacg gctggaataa aaacggggtc
     4501 tttaatatcg aaggtggctg ctatgcaaaa gcaattaatc tttccaaaga aaaagaacca
     4561 cagatttttg acgcaatcaa atatggtgca attttagaga acactgtagt tgcagaagat
     4621 ggttcagtgg actttgaaga caatcgttat acagaaaaca cgcgtgccgc ttatccaatt
     4681 aatcacattg acaatattgt agtaccatca aaagcagcac atccaaatac aattattttc
     4741 ttaactgcgg atgcatttgg tgttattcca ccgatttcaa agttaaataa agaccaagca
     4801 atgtatcatt tcttgagtgg tttcacttct aaattagctg gtacagagcg tggtgtgaca
     4861 gaacctgaac catcattctc aacatgtttc ggcgcaccgt tcttcccgtt acaccctact
     4921 gtttacgctg atctattagg tgaacttatc gatttacatg atgttgatgt ttatcttgtt
     4981 aatactggat ggactggcgg aaaatatggt gtaggacgta gaatcagctt acattacaca
     5041 cgtcaaatgg taaaccaagc gatttctggc aaattgaaaa atgcagaata tacaaaagat
     5101 agtacgtttg gtttaagcat tcctgtagaa attgaagatg taccgaaaac tattttaaat
     5161 ccaattaatg catggagcga caaagagaaa tataaagcac aagcagaaga tttaattcaa
     5221 cgttttgaaa agaacttcga aaaatttggt gaaaaagttg aacatattgc tgaaaaaggt
     5281 agcttcaaca aataaatttg aatactaatt aaagagccaa ccgttgttat agtctaacaa
     5341 tggttggctc ctcttatttt atatggtaaa aatttatagg caattttatt acaacaatgc
     5401 acatttaagg tgaccttcat gccaaactcg catcacttat tcaatggaag cagcacgtct
     5461 tcacataaag taccaatccc ttacgctatg catgttgccc cgctttgcat aaagtactta
     5521 tcgttaactc aacgcaagtt gttcctattc acaaaaagca catacagtta tctgcatgga
     5581 gcacattttc attgaaagcg cataccgctc attcaacgta tatcacacat cttcaaagat
     5641 tgaaagttcc catgcgcaca ccacgtttca tactagctat gcaactcaac ttggttcata
     5701 aactctttaa tataagtcaa agtttcaacc atcgctggtg gtcttggcac atgtccttct
     5761 gccatttgat aaaatgtttc atgcgtagca ccttttaatt ctagttggtc cgctaaataa
     5821 tacgcatgat gaataccaac ttgctggtct ttccctccat gtacaattaa tatcggcgga
     5881 ctgttttcat taatgtttgg aatcgcttgg cgtgcctcat atgccgctcg atcttttttc
     5941 ggatgaccaa tcattctacg taacatccct cttaaatcaa cgcgctcttc atacatcaaa
     6001 tcaatatctg agactccacc ccagatgata taactattta caggtaagtc ttgaaacgtc
     6061 aacaaccctt gtagtccacc tcttgaaaaa ccaaccatat gaataaaagc ttgcggatat
     6121 ttatcatgta gcaatcttaa taattcagtc acatcattta aatcgccacg ataaaattcg
     6181 tctttacctt cactgccatt gttacctcgg tagtatggcc caatcactaa agtttgacta
     6241 tctgaaaatt gcattaatct acctgcgcgc acacgtccta cttggccttt gccacctcgc
     6301 aaatatacta caatgcgttt tacttcatga tgtggtgtca tcattaaagc ttttacttgt
     6361 aaatcatctg acaaatatgt aatttcttct aattgatgcg taaaagattc aattggcatt
     6421 cgtttacgtt tgataaaatc caagtgattg caccctctct acgcatttta aaatggtact
     6481 atcttgcagt aagaaacttc gttgtgtgag ttcaatatca ttgatacagt taaacaacac
     6541 tggccctgct gtttctaaat aatcgttctt gcttaccaat gattcaactt cgataaaata
     6601 tacatctttt acaaaatcag tttgatcatg tgtttcaatg gtatattgtg ctatgtaatg
     6661 aatattttta actttggcgc ctgtttcttc atataattca cgtgtaactg cttcagcact
     6721 gctttccccg cgttcccttt taccaccagg aaattcaata ccccgtaaat tatgtttggt
     6781 aaaaagcaat tgatttttaa acgttggaat agctagcaca tgattaccat ctgctacctc
     6841 attatccttt ttaaatgtca aattaacttg acgattatct ttatccctaa acttcacgcg
     6901 catcacatcc ctacattgta tgttaatata atagttaatt actatcgttg gaggcattaa
     6961 ttatgaaaaa gatattcttg gcgatgattc atttttatca acgtttcatt tcgccactca
     7021 ctccaccaac ttgtcgtttt tatccaacat gttcagagta cactagagaa gcgattcaat
     7081 accacggtgc tttcaaaggc ctttatttag gtatccgtcg tattttaaaa tgtcatccgc
     7141 ttcataaagg tggctttgac cctgttccgt taaaaaaaga caagtcagaa agcaagcatt
     7201 cacataaaca taaccattaa tatggttgta attgagttat atccactaaa ggggggcgaa
     7261 attcgagtcg cccctctttt aatatgcctg aatgcgccac cacatcttgt tcaaaataat
     7321 aacctgctgg tgtcacatct cctggataat cacctttacg agcaagcatc gctgtaaaat
     7381 aacggcttaa accatattcg tacatgccgc caataaccac ttttacacca tgacttttca
     7441 aagtatcaat tgccgtttgc actttatcaa tgccacctag acgaaatggt tttaatacaa
     7501 caactttcac attgtataat tctatcaaat taattatgtc caacaacgat gttgcctttt
     7561 catcaagggc tattggaggt attgttccat ccactacgtc atcaagcatg gagatatctt
     7621 taaatggctc ttcgatataa agaacctgtt cacgcgctaa taactgtaac tgtgtgaaat
     7681 cttgacgatc caaggactca tttgcatcta taaccaattg aaagtgaaac tctaattccc
     7741 gtaacactct aatttgatgc atgatttgag gtgtccattt taatttaatt ctggccggct
     7801 tagttgcttt taatgactct agttgtttat ttgataagcc gctcactgtc gctccatatg
     7861 ctactgaaaa tgaaggcagt acatgaaata tttgatacaa tgccatgaca atagttgccc
     7921 ttgcagcagg cgtattttcc aatgaatcta ctaattttag tgctgcttca tacgtttcaa
     7981 atgatttatt tctattatct tcgaaccatt gctcaattac atgtttcact gaagcaattg
     8041 tttcatgatc ataccaatct gtttgaaaag cgttacattc cccgaaatat gcatttcctt
     8101 tgtcatcaat caattcgata aacaaacaat cacgatgcgt taaagtgact ttcggtgtta
     8161 caatttgtga cttaaatggc tcactatatt tataaaaatg caaagctgtc aacttcatca
     8221 aatcatcctc tatacaactt atttctttgt aatttacctg ttgatgtata aggtaaagta
     8281 tcaacctttt caaagtgttt cggtacttta tatttcgcta aatgttgtga taaatatgca
     8341 atcaattgtg cctttgaaat gtcactttca ctgacaaaat ataatttagg cacttggccc
     8401 caagtatcat caggatgccc tacacatact gcgtcactga tacctggaaa ttgcttcgct
     8461 accgtttcaa tttgatatgg ataaatattt tcaccgccac taataattaa atctttacgt
     8521 cggtcataaa tcatgacata accttcatga tctatttcag caatgtcacc tgtattaaaa
     8581 taaccatttt caaacgtacc cgttaaatct gttggataca aatatccatt catcacattg
     8641 gcgcctttaa tcattaattc tccatgacct tctttattag gatttttaat ttttacgtct
     8701 acattggcac ttggcatccc tacagtgtca ggacgtgcat gcaacatttc cggtgttgct
     8761 gttaaaaatt gcgaacatgt ctcagtcata ccaaatgaat tataaattgg caggttatat
     8821 tgtaatgccg tctctatcat agtggcagat aatttagcac cgccgagtaa tattttttgt
     8881 aaattataag gttcatgtaa accttgttgc ataagccaat ttaaagtttg tggcacaagc
     8941 gaaatgtgcg tgattcgttc atttttaatc atcgttaaaa tttgttcggc attgaattta
     9001 tcaacaatgc gcacagtaaa accttcaata acagctctta aaagtacact gagacccgaa
     9061 atatgataaa tcggcaagac agatagccaa ttagtgtcac gatcaaatcc caagctctct
     9121 ttacatccga ttgcactggc ataatgatta cgaaacgttt gtggcaccgc tttttgaggg
     9181 cccgttgtcc ctgatgtaaa cataatcgat gcaatgtcat ctaaattaaa tgatgtattt
     9241 aatatgttgg acggcgactc tttcggcacc acagtttcat tcgatgtatc atattggata
     9301 cccattgtgt tgtccaacaa accgttcgtt gtaatatccc ttccagcgaa ttcaatatca
     9361 tccagcgata caatttgaaa ccctcgtaat tccagtggca aggtacaaaa aatcaattgt
     9421 acatcgattg acttcatctg attcgtcatc tcattaggtg tcaaccttgt attaatcatc
     9481 gcaatttcaa tatttgccaa ccaacatgca tgtattaaaa tgatcgattg aatcgaatta
     9541 tctatgtata gcccaacacg agattgttga taagccttga gtcttttagc caatagactc
     9601 gcttcacagt ataaattttg ataagtataa gattcttgac cgtctgttat cgcaatatga
     9661 tgtccatttt gttgtgcttg tttatataac caaaagtcca tgcgttattc ctccaaaatc
     9721 atttacatta taattataac gattttatga cattctagca gtggttatgt ttaaaaatat
     9781 aaaaaagtag acgaattgat gcattgatat gattgttata atgctcaata catatcgtta
     9841 tatcattcgt ctactattat cagttatttt tatttaattt tagtgtcatt ctgtcatttt
     9901 gatgtggtga tttacccatt gttgccacat catctgcaat gtcaattggt atacggttca
     9961 tgtcttgtaa tgcacttaaa tggaatactt catcatctaa attttcaatg agatatacat
    10021 aatatgttac cttgtccttt ttatatttta acgttttcca aaagtccggc ttgcaattca
    10081 atacattatc cggaatatat tcaataaata agtaacgttt gctgcctact ttgtctatga
    10141 aatattttgc agtgcctttt tctatacctc ttatatgtgc atagtctgct gaaaagtaaa
    10201 tactacctat tgtttcatta tgttgttgta tttcaaatcg ttggcctact attttattat
    10261 ttgtgccaca actacttaaa aaaatcagta gatatagcat taaacatatt ttcatcccct
    10321 tgaattttaa aaactttttc aaaagcaaca cctctaaaaa taaatacaat atattatagc
    10381 aaatagaaat tattattttg ttaaattaag ttgtcatgtt cgtgtcattt tgagtcgtaa
    10441 tacaacttta caattattaa attaacactt ctacaatcca aaaatatttt taaagttttg
    10501 aaaaaattaa agtatttcca ctactaattt ggtaaaatat gattatgtga tatagtgaaa
    10561 gcgttttaca cttaataact ccctcttaaa tgcatccagg ttttatgtag taaatcatga
    10621 aaataacata taaatataga ggagatttac ctttgaatac agagaacaac aagaatcaaa
    10681 accaatctgt taaaaattct gaaagacgcg gcatgttaaa aggatgcggc ggttgcctta
    10741 tttcttttat tttattaata atcttattat cagcctgttc aatgatgttt agtaataatg
    10801 acaatcccac tagtaatcaa tcatcaaaaa cgcaattaac tcaaaaagat gaaaataaaa
    10861 atgaagataa gcctgaggaa aaatcagaat cagaaacaga taaggattta caatcaaccg
    10921 aagaagtacc cgcaaatgaa aatactgaaa ataatcaaca tgaaattgat gaaataacaa
    10981 caaaagatca atcagacgat gatattaaca caccaaacgt tgcagaagat aaatcacaag
    11041 acgacttgaa agatgattta aaagaaaagc aacaatcaag taaccatcat caatctacgc
    11101 aacctaagac ctcaccatca actgaaacaa acacgcaaca atcatttgct aattgtaagc
    11161 aacttagaca agtatatccg aatggtgtca ctgccgatca tccagcatat cgaccacatt
    11221 tagatagaga taaagataaa cgtgcatgtg aacctgataa atattaaaca acaagcgaat
    11281 tgaattcaaa ttgtatttag ctttatgcac taatcacata gtaaataatg agggagattt
    11341 tttaggcatg agcaatcaat tcaaaagcga agaagagcga agacaatggg aacaattcca
    11401 agctttccaa aatcaacaaa accaacagaa ccagcaatac ggacaaaaga aatctaaaaa
    11461 aggatggttc tggggctgtg gtggttgtct agtattattt attttaatta tcatcggtat
    11521 ttcagcttgt acagctggta ttacaggtaa ccttggcgga aatagttcta aagaaacgaa
    11581 caaaacccat aaaatcggtg aaactgttaa aaatggcgac cttgaagtca ctgtaaattc
    11641 agtggaaact atgaaatctg taggaccgtc tcttgcacca acaaacgcta aaggtacatt
    11701 tgtcgttgct gatgtgacaa ttaaaaacaa aggtaaagaa gcgttaacaa ttgatagttc
    11761 aatgtttaag ttaaaatccg gtgataaaac atttgaagca gataatacag gttcaatgtc
    11821 tgctaatcaa agtgacaatg gtagtataga aaattcattt ttcttacagc gtataaatcc
    11881 tgatagcact gcacaaggta aaattgtttt cgatgtgtca gaaaacatag ccaacgcaaa
    11941 agataaaaaa ttagaagtta tttctagttt atttagcgtc aagaagatta catttgattt
    12001 atccgaagct aaaaaaacat caaaagctaa aaaagacaag caagatacag aagtagctgt
    12061 tgcgagttca aatagcgata atataagtta tgaagcttcg gctactacac ctgctacaac
    12121 ttctagtgcg gatactgatt ctgaagatag cgaaaagtct agtaaagatg aggataagca
    12181 gaatgcgtct aaaagtgata aatctagtgt agaaaaaagt gaatctaatg aggaaactgc
    12241 tcctgtagag cctatgcgcc agagcaaacc taccactagt gaagcaccac ctagtcaaaa
    12301 tattcacaat gaagatagca tgtacgacgc ttcaacagaa taaaatttca gggtagctcg
    12361 gctacccttc ttttacggaa aaattaatta tacataatca aatcaaggag ataaaaaaat
    12421 gaaattcaaa gctatcgttg caatcacatt atcattgtca ctattaactg cttgcggtgc
    12481 taatcaacat aaagaaaata atagtaaatc aaataacact aataaaaaga cgcaacaaac
    12541 tgacaacact acaaagtcaa atacagacaa gcaaatgaca ccacaagaag ccgaagatat
    12601 cgttcgaaac gattacaaag caagaggtgc taacgaaaat caaacattaa attataaaac
    12661 aaatcttgaa cgaagcaatg aacatgaata ttatgttgaa catctagtcc gcgatgcagt
    12721 tggcacacca ttaaaacgtt gtgctattgt taatcgacac aatggtacga ttattaatat
    12781 ttttgatgat atgtcagaaa aagataaaga agaatttgaa gcatttaaaa agagaagccc
    12841 taaatacaac ccaggtatga gtgatcaagc tgaaatggat aatgagtcgg aagacattca
    12901 acatcatgat attgacaata acaaagccat tcaaaatgac ataccagatc aaaaagtcga
    12961 tgataaaagt gataaaaatg ctgttaataa agaagaacaa cacgataacg gtacaaataa
    13021 ttctgaagaa actaaagtta aataaggata tactttgatt aatcgtaatt tttaggagaa
    13081 ccactatgat aacatttgaa aatatacaac aacttgaaaa atatacctta atgactatgc
    13141 atggtctttt taatcaactt aaactcggta ttatttcaat cgacaatgca gagcatacct
    13201 tctttacacc ttatatgatg gaatcactct cttccctagg tgtgaaacca gacattatcg
    13261 atttaattca caaagggaca gagttagaag actttgcagc atttaattta tcaattgatg
    13321 atacagttac agtctgttta caaagaactg aagaactatt aaaacaatac aaaaatgtag
    13381 aattcaatga caaaatatta atcaattggc gcgttataca aaagtaatag acatataaaa
    13441 gtcgaacgta actaagtggg tattgatttt attctttcta agttacaagt atttcatttt
    13501 ataaagtttg aaaagaggtt tattgaaatg gagaaaaacg aatatacagc taaatataat
    13561 gaatataatc aattattaga cgctacttac tcgcaagctg tagcatacct tttaaataaa
    13621 tatggcgctg taaccgatga ctattataag gaaaaatcat acacacgatt tttaaatgga
    13681 gaaatcaaaa gtattacaaa aggaaaatac actagagcta gcgaaggatt atattgtcat
    13741 cacataagcg aagacaaatt ccaaaactta tctgacctaa gattcatttc cgaatttaag
    13801 tactcataca actatcaaaa gaaagaaaac ttagtttact gcgatttaat cgagcattta
    13861 attttacatg caattattac aaaagaatct gatggtcaat ttggcgcggc tggattatgt
    13921 caaatgatca aaccaacagt cattgattgg tacattagcg aatataatcc aaaaccagca
    13981 tggatgcaag ccaccaaagc acgtgcctat ttgcctagaa tattagtaga gaaactactc
    14041 attaaaattg acgatatgtt agaaggaata gaaatatatg atttccttga gtctagataa
    14101 atgattaatg gagatttatt ttttgctgtt gagattttgt tatagatgtt taaacctgta
    14161 attaaatata ttttataaaa tagaccacgc atacctatct ataaacggac aatgtttata
    14221 aatgagtttg cctggtcttg aattgtatta gttttctttt ggttttaata aatcgactag
    14281 attttcacaa tatttatcaa atatgtattc ctaaattata cagccttaat ccagcagcta
    14341 ctttcgaaac ttccaactta gttgatataa ggttcaatag tttgtttcgt tctttttcag
    14401 ataaaccaga acttaaattg atattattga cttcataaaa attatagact aatgcctcta
    14461 tttgcttttt aggcataagt aagtcgactg aaaactgatt tacgtcgctt tcataaatca
    14521 tttcatgtaa attctttaga ctattatcgt tgttatctct cattaagtct gaatttttaa
    14581 ataaataacg gcccaattca cgagctattg caaatcttgt attattaatc gagtgattat
    14641 tattaatata gattgttctt ccacttaaat aacccgaagt attaccctcc attttaatat
    14701 atttaacatt taaattaagt tgaaataata gcttgtctat gtcaatagca aagtgttcag
    14761 aagtaataaa aagttgatcc attttgtcct ttataaatgc ctgaaataat cgaactattt
    14821 ttgattctaa aatatcttca taatgaactt tctcaataac tttcaattga ttccccaccc
    14881 taactaaaaa attgaaccta catcatttaa taaatttaaa actataggtg taaacattat
    14941 taaaataaaa ctcctccact actaaatgaa acggagggac atgatttcaa aataaaatac
    15001 ctttttttat aaatttatta taatattttc cattatactg tacaaccgaa tctaatccaa
    15061 cgatcccgaa aagaagaaca aaggtggttc tgcttcataa tcacttttaa ctaagtgttc
    15121 atttttaatt atttgatcga cggttttcca attttttact tcttgctctt ttaaaaaatg
    15181 gctatgaaaa attctatcct catagatttt ttcatagcca atgctaattt gtttcatgtc
    15241 atttctttaa aattcctaaa aatatataaa ctaaaagcat aagtaacaca gcaaaaattg
    15301 ccgaatatat aattattgaa aaagcattgc tttgcattgg aactaaataa tttaaagtac
    15361 aaaataataa taatgctaaa ataccaactt taagtgaata ttttaatcta tccataaaat
    15421 cacccttact gatatcccca tttttctcct atcagaacgt attccccggc tgcattcttt
    15481 ttagttttta attttaaata tattctctta ctagtatcaa tattcgatgc agctatagat
    15541 ccaaggaaac taccaacacc tgcgccaact aaacctcctg ttagtgcaga aataacgcta
    15601 atagtccccg cacctaaagc agctattgtt tttgtatatg cagaagaaag atataacgtt
    15661 gcagtatctt tacctgtttc tacatattga gttttacccg ctcttaattg gtcttcagct
    15721 ttaaattttt ttatttcttc ttttgtaaat atatcttcca gtttataacc ttttttctca
    15781 agttcatcaa ataaattttg gttactcaaa tatataacct ttgcttgaga atggtctaac
    15841 ttatcttcag catgagctac atctgaatta taagataatg aaattggact aacaaataat
    15901 acaccagcag ctaataataa tgatttttaa ttcgtttttc at
//
LOCUS       DAPSKH010000061        15731 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPSKH010000061 DAPSKH010000000
VERSION     DAPSKH010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15731)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15731)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15731
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.061"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(69..998)
                     /locus_tag="RPH49_002169"
     CDS             complement(69..998)
                     /locus_tag="RPH49_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001574632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDY5125294.1"
                     /translation="MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGT
                     ICLIILNIIINPEVFTIHFYNNQSFNNTWIVGGLLGVSFLTGNLLLLPKLGATLTVIA
                     TVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIIGIVIMNQFNKNNLLLTDQKY
                     LLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSITLLILTAIFNRSL
                     KLNTYHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILID
                     HFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF"
     gene            complement(1194..1418)
                     /locus_tag="RPH49_002170"
     CDS             complement(1194..1418)
                     /locus_tag="RPH49_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499185.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2922 domain-containing protein"
                     /protein_id="HDY5125295.1"
                     /translation="MTKTLELSFKSSLDKPVKLQLPQLNNIVTEQVARDSMNALVDLN
                     IIKSNSGAITKVHSAQIIDKTTTVLFEAKK"
     gene            complement(1435..1638)
                     /locus_tag="RPH49_002171"
     CDS             complement(1435..1638)
                     /locus_tag="RPH49_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125296.1"
                     /translation="MSKTNHITIVLSFTKLDTNGKQTEFKRRFANINPEVSNDQIKTF
                     SKLIERLTGETYNNIEVIKSVSI"
     gene            1793..2353
                     /locus_tag="RPH49_002172"
     CDS             1793..2353
                     /locus_tag="RPH49_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDY5125297.1"
                     /translation="MNKVEVIKCNDDINKMYDALKARSDRDYLFFKLAIHSGMKITEL
                     LTITVKDTKRLIEKGTLSELCKAHYHSLIKIRLPETLSNELLHYIENKSLSNEDVLFQ
                     SLRTNQVLSRQQAYRIIHQAAIKAGIENVGLTTLRKTFAYHAYQKGIPIPVIQKYLGH
                     QSAIETLNFIGLENECEHSIYISLQL"
     gene            2372..4774
                     /gene="mnhA2"
                     /locus_tag="RPH49_002173"
     CDS             2372..4774
                     /gene="mnhA2"
                     /locus_tag="RPH49_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit A"
                     /protein_id="HDY5125298.1"
                     /translation="MSLVYLLIAVLVIMAMILLTSKRRAMAKYAGYIALTAPVIASIY
                     FLLQVPSVIKQHYLSVSVPWMTSLDINVDLRLDGLSLMFSLIISLIGIAVFFYATQYL
                     SSRKDNLPRFYLYLTLFMFSMLGIVLADNTILMYVFWELTSVSSFLLISYWYNNGDSQ
                     FGAMQSFMITVFGGLALLVGFIMLYIMTGTNNITEILGQADHIKNHALFIPMIIMFLL
                     GAFTKSAQFPFHIWLPRAMAAPTPVSAYLHSATMVKAGIFLLLRFTPLLGLSNMYIYI
                     VTFVGLITMLFGSITALKQWDLKEILAYSTISQLGMIMAMVGIGGGYAQHQQNAIASI
                     YVFVLFGALFHLMNHAIFKCALFMGVGILDHEAGSRDIRILSGMRQLFPKMNLVMTIA
                     ALSMAGVPFLNGFLSKEMFLDALTQTGQLSQFSLISMISIVFVGVIASVFTFTYALYM
                     VKEVFWTKYDSKVFTKKNIHEPWLFSLPSLILMVLVPVIFFVPNIFGKGIIVPALRAV
                     SGGNHQIDQLAPHVSQWHGFNIPLLLTIIIILLGSVLAIKVDWKKVFTGKIRQISVSK
                     SYEMVYRHFEKFATKRFKRVMQDRLNQYIIMTLGIFMIIIGYGYIRIGLPKVHQLHVS
                     EFGALEIILAIVTVTIGISLIFIRQRLTMVILNGVIGFVVTLFFIAMKAPDLALTQLV
                     VETITTILFIVSFSRLPNVPRSNANKKREIIKISVSLLMALIVVSLIFITQQTDGLSS
                     ISDFYLKADKLTGGKNIVNAILGDFRALDTLFEGLVLIITGLGIYTLLNYQDRRGQDE
                     RE"
     gene            4761..5186
                     /gene="mnhB2"
                     /locus_tag="RPH49_002174"
     CDS             4761..5186
                     /gene="mnhB2"
                     /locus_tag="RPH49_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit B"
                     /protein_id="HDY5125299.1"
                     /translation="MKENDVVLRTVTKLVVFILLTFGFYVFFAGHNNPGGGFIGGLIF
                     SSAFILMFLAFNVEEVLESLPIDFRILMIIGALVSSITAIIPMFFGKPFLSQYETTWL
                     LPILGQIHVSTITLFELGILFSVVGVIVTVMLSLSGGRS"
     gene            5183..5527
                     /gene="mnhC2"
                     /locus_tag="RPH49_002175"
     CDS             5183..5527
                     /gene="mnhC2"
                     /locus_tag="RPH49_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit C"
                     /protein_id="HDY5125300.1"
                     /translation="MNLILLLVIGFLVFIGTYMILSINLIRIVIGISIYTHAGNLIIM
                     SMGTYGSSRSEPLITGGNQLFVDPLLQAIVLTAIVIGFGMTAFLLVLVYRTYKVTKED
                     EIEGLRGEDDAK"
     gene            5517..7013
                     /gene="mnhD2"
                     /locus_tag="RPH49_002176"
     CDS             5517..7013
                     /gene="mnhD2"
                     /locus_tag="RPH49_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit D"
                     /protein_id="HDY5125301.1"
                     /translation="MLSNLLILPMLLPFLCALILVFLKNNDRISKYLYLGTMTITTII
                     SLMLLIYVQRHRPITLDFGGWSAPFGIQFLGDSLSLIMVTTASFVITLIMAYGFGRGE
                     HKANRYHLPSFILFLSVGVIGSFLTSDLFNLYVMFEIMLLASFVLITLGQSVEQLRAA
                     IIYVVLNIIGSWLFLLGIGLLYKTVGTLNFSHIAMRLNDMGDNRTVTMISLIFLVAFS
                     AKAALVLFMWLPKAYAVLNTELAALFAALMTKVGAYALIRFFTLLFDQHNDLIHPLLA
                     TMAAITMVIGAIGVIAYKDIKKIAAYQVIISIGFIILGLGTNTFAGINGAIFYLVNDI
                     VVKTLLFFIIGSLVYITGYRQYQYLNGLAKKEPLFGVAFIIMIFAIGGVPPFSGFPGK
                     VLIFQGALQNGNYIGLALMIITSLIAMYSLFRILFYMYFGDKDGEEVNFKKIPLYRKR
                     ILSILVVVVIAIGIAAPVVLNVTSDATELNTSDQLYQKLVNPHLKGED"
     gene            7014..7496
                     /gene="mnhE2"
                     /locus_tag="RPH49_002177"
     CDS             7014..7496
                     /gene="mnhE2"
                     /locus_tag="RPH49_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit E"
                     /protein_id="HDY5125302.1"
                     /translation="MNQIVLNIIIAFLWVLFQDEDHFKFSTFFSGYLIGLIVIYILHR
                     FFSDDFYVRKIWVAIKFLGVYLYQLITSSISTINYILFKTKDMNPGLLSYETRLTSDW
                     AITFLTILIIITPGSTVIRISQDSKKFFIHSIDVSEKEKDSLLRSIKHYEDLILEVSR
                     "
     gene            7493..7795
                     /gene="mnhF2"
                     /locus_tag="RPH49_002178"
     CDS             7493..7795
                     /gene="mnhF2"
                     /locus_tag="RPH49_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit F"
                     /protein_id="HDY5125303.1"
                     /translation="MIQTITHIMIISSLIIFGIALIICLFRLIKGPTTADRVVTFDTT
                     SAVVMSIVGVLSVLMGTVSFLDSIMLIAIISFVSSVSISRFIGGGHVFNGNNKRNL"
     gene            7770..8207
                     /gene="mnhG2"
                     /locus_tag="RPH49_002179"
     CDS             7770..8207
                     /gene="mnhG2"
                     /locus_tag="RPH49_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter Mnh2 subunit G"
                     /protein_id="HDY5125304.1"
                     /translation="MEITKEIFSLIAAVMLLLGSFIALISAIGIVKFQDVFLRSHAAT
                     KSSTLSVLLTLIGVLIYFIVNTGFFSVRLLLSLVFINLTSPVGMHLVARAAYRNGAYM
                     YRKNDDHTHASILLSSNEQNSTEALQLRAKKREEHRKKWYQND"
     gene            8547..10589
                     /locus_tag="RPH49_002180"
     CDS             8547..10589
                     /locus_tag="RPH49_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002465267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDY5125305.1"
                     /translation="MEIFETILIFIAVVILSSFVHTFIPKVPLAFIQIFLGMLLFITP
                     IPVQFNFDSELFMVTMIAPLLFVEGVNVSRVHLRKYIKPVMMMALGLVITTVIGVGLF
                     IHWIWPDLPIGAAFAIAAILCPTDAVAVQAITKGKVLPKGAMTILEGESLLNDAAGII
                     SFKIAVGVLVTGAFSLVDAVQLFLIASIGGAVVGLLIGMALVRFRLTLMRRGYENINM
                     FTIIQLLTPFVTYLIAELFHASGIIAAVVAGLVHGFERDRIMQVRTQLQMSYNHTWNI
                     LGYVLNGFVFSILGFLVPEVIIKIIKTEPHNLIFLIGITIVVALAVYLFRFVWVYVLY
                     PYFYLAISPFQKMMTKNDDDNPTTEKPPKRSLYALIMTLCGVHGTISLAIALTLPYFL
                     AGHHAFTYRNDLLFIASGMVIISLVVAQVLLPLLTKPAPKTVIGNMSFKVARIYILEQ
                     VIDYLNQKSTFETSFKYGNVIKEYHDKLAFLKTVEKDDENSKELERLQKIAFNVETKT
                     LESLVDEGQITNSVLENYMRYAERTQVYRQASLIRRMIVLLRGALLKRRVQTRVNSAS
                     SLSVTDNLMELNKINKLVHYNVVSRLSKETTKDNTLEVGMVCDGYLMRIENLTPSNFF
                     NSASEDTITKIKLNALREQRRILRELIDTDEVSEGTALKLREAINYDEMVIVDSMT"
     gene            complement(11484..12413)
                     /locus_tag="RPH49_002181"
     CDS             complement(11484..12413)
                     /locus_tag="RPH49_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDY5125306.1"
                     /translation="MKKLVPLLLALLLLVAACGTGGKQSSDKSNGKLKVVTTNSILYD
                     MAKNVGGDNVDIHSIVPVGQDPHEYEVKPKDIKKLTDADVILYNGLNLETGNGWFEKA
                     LEQAGKSLKDKKVIAVSKDVKPIYLNGEEGNKDKQDPHAWLSLDNGIKYVKTIQQTFI
                     DNDKKHKADYEKQGNKYIAQLEKLNNDSKDKFNDIPKEQRAMITSEGAFKYFSKQYGI
                     TPGYIWEINTEKQGTPEQMRQAIEFVKKHKLKHLLVETSVDKKAMESLSEETKKDIFG
                     EVYTDSIGKEGTKGDSYYKMMKSNIDTVHGSMK"
     gene            complement(12410..13246)
                     /locus_tag="RPH49_002182"
     CDS             complement(12410..13246)
                     /locus_tag="RPH49_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDY5125307.1"
                     /translation="MLEFVEHLFTYQFLNRALITSIIVGIVCGTVGSLIVLRGLSLMG
                     DAMSHAVLPGVALSFLFGIPMFVGALITGMIASIFIGYITSSSKTKPDAAIGISFTAF
                     LASGIIIISLINTTTDLYHILFGNLLAITNSAFLTTIVIGSIVLILIIIFYRPLMIST
                     FDPTFSRMSGLNTTLLHYFVMLLLSLVTVASIQTVGIILVVALLITPASTAFLISKKL
                     YSMMIIASLISVISSIVGLYYSYIYNIPSGATIVLCTFVIYIITLFFTKFTNRKKRGS
                     LT"
     gene            complement(13240..13983)
                     /locus_tag="RPH49_002183"
     CDS             complement(13240..13983)
                     /locus_tag="RPH49_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDY5125308.1"
                     /translation="MLETKDLNLFLGNKHVLKNISLSIPVRGEIIGIMGPNGAGKSSL
                     IKSLIGEFNATGTKLLYNKPIQQQLQHITYIPQKAHIDLDFPISVEQVILSGCYKEIG
                     WFRRPNKSARDKLKQLLSDLELESLRHRQISELSGGQLQRVLVARALMSESEVYFLDE
                     PFVGIDFSSEKLIMTKIENLKQQGKLILIIHHDLSKAKQYFDRIILLNQTLRYFGDSE
                     EAMSVTRLNETFMSSTDCSDPSQRSNITC"
     gene            14105..14749
                     /locus_tag="RPH49_002184"
     CDS             14105..14749
                     /locus_tag="RPH49_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDY5125309.1"
                     /translation="MLTEEKEDYLKAILTNNGDKNFVTNKILSQFLNIKPPSVSEMVG
                     RLEKAGYVETKPYKGVRLTEDGLTHTLDIIKRHRLLELFLIEILKYNWEEVHQEAEIL
                     EHRISDLFVERLDSLLNFPETCPHGGVIPRNNEYKEKYITTILNYEPGDIVTIKRVRD
                     KTDLLIYLSSKDISIGNEVEIVSKDEMNKVIIIKRNDNVIIVSYENAMNMFAEK"
     gene            complement(14829..15581)
                     /locus_tag="RPH49_002185"
     CDS             complement(14829..15581)
                     /locus_tag="RPH49_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M50 family metallopeptidase"
                     /protein_id="HDY5125310.1"
                     /translation="MNYLSNFFNTTIQLNIYIIVIVAACYIAIHQYRHKAVLNYLDVI
                     LNYIPVLTHEFGHVLFNKLAGGRAKDLVIVTSPRERQQTLQQGFAITQSRHLAGQWLT
                     TIGGYFMPPIMLLIGLASSHYQIPSFFIFTYLLIFIYFLILTSRKGSPIVVITLISIM
                     LYFILKDENIVEIQLLVTMSYQYILGVLLGEVLQSSWTIAKLTFQRPSPQWDGSALKE
                     LSHVPIFIYSTIWIIFNLYAVNILLKYTHLIN"
BASE COUNT         5249 a         2254 c         2686 g         5542 t
ORIGIN      
        1 gaccacaaaa aaatagctta tcacttttaa aaataattac aagttaaaat gataagctaa
       61 aagttaattt aaaataatct taaaagtata atgcctgtca aaatacataa tagaccaata
      121 gtttttctgg atgtcattgc tattttaggt gaaccaaata atccaaagtg atctatcaat
      181 atgcccatta gaatctgacc aaacatccca ataagtgttg ttaatgctgc acccatatga
      241 ggcattaaga taatgttagc tgttacaaaa gccatgccta gtataccgcc agtaaaatag
      301 ataggtttta gtttgccgaa tttcaaatga tatgtattta gttttaaaga acgattaaaa
      361 atagcggtta aaatcaatag cgttattgac ccaattgtaa atgatactaa tgatgcaaag
      421 gctggtgaat gagtatgact tgctaaagca ctattaattg tcgtttgaat aggtggaaag
      481 aaaccaaaaa taaatcctaa tagaagccaa aacagtaaat acttttgatc agttagtaat
      541 aaattattct tgttaaattg attcattatg acgataccga taatgagtaa caatacacca
      601 attgctttaa ttaaattaaa atcatgaatt gtagcaccaa ataagccaaa tgtatcaatt
      661 atgacaccca taataatttg acccgcaact gttgcaatta cagttaatgt tgcacctaat
      721 tttggcaata acaataaatt gccagttaaa aagctaaccc caagcaaacc accgactatc
      781 catgtattgt taaatgattg attattgtaa aagtgaatag taaatacttc tggattgata
      841 atgatattta aaataattaa acaaattgtt ccaactgaaa atgaaatgaa tgaagtatag
      901 aaaggcgatt tagtatacag tgatagtctt gaattgacag atgtttggat aggaataagc
      961 attccaacta ggacaccaat gatatagaaa agaagcatat gaataaagtc tcactttcca
     1021 aagttaataa taaaaatcat atgtatacat tatcattata gagaaaatat acaactcatt
     1081 tacaataatg ttgaaaaaaa cagggcatta acacaacaaa aacaccctag acaatcatca
     1141 tgaaagtcta tggtgttagt atttatacta aattaattgc gctttcttta tatctatttc
     1201 tttgcttcaa ataaaacggt cgtcgtttta tcaataattt gagcagaatg tactttggtg
     1261 atagcgccac tatttgactt tataatattt aaatctacta atgcattcat actatcacgt
     1321 gcaacttgct cggttacgat gttgtttaat tgtggtaatt gcaatttgac aggtttgtct
     1381 agtgaagatt taaaacttaa ttcaagtgtt ttggtcatga aagtgtcctc ctgattaaat
     1441 tgatacagat ttgatgactt cgatgttgtt gtatgtttct ccagtaagtc gttcgataag
     1501 tttgctaaat gttttaattt ggtcgtttga tacttcagga ttaatattgg cgaatcgacg
     1561 cttaaattct gtttgtttac catttgtatc tagttttgta aatgataata caattgtaat
     1621 gtgatttgtt ttactcatat tttaaaacct cctttcacac tatatatcga aagaaaaaaa
     1681 taattgggtt aattttatta ttcttgttta aattctataa aaaaggttat aattatatgt
     1741 gacttaaata cttaatgttt atgattaaga cacttaaagc gaggtgggac atatgaacaa
     1801 ggtagaagta attaaatgca atgatgatat taataaaatg tatgacgcac tcaaagctcg
     1861 atctgatagg gattatttgt tttttaaatt agctatacat agtggtatga aaattacaga
     1921 attattaaca attactgtta aagatactaa acgactgatt gaaaagggga cactaagcga
     1981 attgtgtaaa gcccattatc actcattgat taaaattaga ttgccagaaa cattatctaa
     2041 tgagttactt cactatattg aaaacaaaag tctgtcaaat gaagatgtat tatttcaatc
     2101 attgagaact aatcaagtat tatctaggca acaagcctat cgtattattc atcaagcagc
     2161 aattaaggct ggcatagaga atgtaggact aacgacattg cgtaagacat ttgcgtatca
     2221 tgcatatcaa aagggcatac ctattcctgt cattcaaaag tatttagggc atcaatctgc
     2281 tattgaaaca ctaaatttta tcggtttaga aaatgaatgt gaacacagta tttatatttc
     2341 attacaatta taacgacaaa ggaggctaat aatgagtttg gtttatctat taattgccgt
     2401 actagtaatt atggcgatga tattattaac atctaaacgt agagcaatgg ctaaatatgc
     2461 aggatacata gcactgactg cacctgtaat agcatctatt tattttttgt tacaagttcc
     2521 atcagtaatt aaacagcatt atttgtctgt ttccgttccg tggatgacct cattagatat
     2581 taatgtagat ttacgtttag atggtttgag tttaatgttt tctcttatta tttcacttat
     2641 tggaattgct gtattcttct atgcaacaca atatttatcc tctcgtaaag ataatttacc
     2701 aaggttttac ttatacttaa cgctatttat gtttagcatg ctcggtattg tattagctga
     2761 taatacaata ttaatgtatg tgttttggga actaactagc gtatcatcat ttctattaat
     2821 ttcatattgg tataacaacg gagatagtca atttggtgcg atgcaatcat ttatgattac
     2881 agtatttggt ggtttggcat tattagttgg ttttatcatg ttgtatatca tgacaggaac
     2941 gaataacatc acagagatat taggacaagc agatcatatt aagaaccatg ctttatttat
     3001 ccctatgatt atcatgtttt tattaggtgc atttacaaag tctgcacaat tcccatttca
     3061 tatttggtta ccaagggcaa tggcagcgcc tacacctgta agtgcatatt tacattcagc
     3121 cactatggtt aaagctggta tctttttatt acttagattt acacctttgt taggtctaag
     3181 caatatgtat atttatatcg taacctttgt cgggttaata acaatgttat ttggttcaat
     3241 cacagcttta aaacaatggg atttaaaaga aatcctagca tattcaacaa tcagtcaact
     3301 aggaatgatt atggcaatgg tcggtatcgg tggtggatat gctcaacacc aacaaaacgc
     3361 aatagcatct atttatgtat ttgtattatt tggtgcgcta tttcatctaa tgaatcatgc
     3421 catctttaaa tgtgcgcttt tcatgggagt aggtatttta gatcatgaag caggttcaag
     3481 ggatatacga attttaagtg gaatgcgtca actatttcct aaaatgaatc tagtcatgac
     3541 gatagcggct ctatctatgg ctggagtacc atttttaaat ggatttttaa gtaaagaaat
     3601 gttcttagat gcattaacac aaactggaca attatcccaa tttagtttga tttcaatgat
     3661 aagtattgtg tttgttggtg ttattgcgag tgtttttaca ttcacatatg cattatacat
     3721 ggtaaaagaa gtattttgga caaaatatga ttctaaggtt tttactaaaa aaaatatcca
     3781 cgaaccatgg ttgtttagtt taccatctct tatattaatg gtgctagtac ctgtaatctt
     3841 ttttgtacca aatatatttg ggaaggggat tatcgttcca gcattaagag ctgtatcagg
     3901 tggtaatcat caaattgatc aattggcacc acatgtttcg caatggcatg gatttaacat
     3961 accgcttctt ttaaccatca tcattatttt attgggtagt gtactagcaa tcaaagtaga
     4021 ttggaaaaaa gtgttcacag gtaaaattag acagatttca gtttcaaaaa gctatgagat
     4081 ggtatatcga cattttgaaa agtttgctac gaagcgattt aaacgtgtta tgcaagatcg
     4141 tttaaaccaa tacattatta tgaccttagg catatttatg attatcattg gatatggtta
     4201 tattcgaatt ggacttccaa aagtacatca gttacatgtt tctgaatttg gggcattaga
     4261 aattatatta gcaatcgtaa ctgtcacaat tggtatttct ttaattttta tacgtcaacg
     4321 actgacaatg gtcattttaa atggagtcat cggatttgtt gtgaccttat tctttatagc
     4381 aatgaaagcc cctgatttag cattgactca gctagtagtt gaaacaataa cgacgatact
     4441 atttattgtt agtttttcaa gattaccaaa cgtgccaaga tctaacgcta acaaaaaaag
     4501 agaaataatt aaaatttctg tatcactctt gatggcactt attgttgtat cattaatttt
     4561 tattacacaa caaacagatg gtttatcatc aatatcagac ttttatttaa aagctgacaa
     4621 actaacaggt ggtaaaaata ttgtaaatgc gatacttggt gactttagag cattagatac
     4681 attatttgaa ggattagtgt taattattac tgggctaggt atttacacat tattaaatta
     4741 tcaagatcgg aggggacaag atgaaagaga atgatgtcgt gttaagaacg gtcacgaaac
     4801 ttgttgtatt tattttattg actttcggat tctatgtctt cttcgcaggt cataataatc
     4861 ctggtggtgg ctttattggt ggtttaatat ttagttcagc gtttatttta atgtttctgg
     4921 cttttaatgt tgaagaggtt ttagaaagtt taccgattga ttttagaatt ttaatgatta
     4981 ttggagcatt ggtatcatct attactgcga taatacctat gttttttgga aaaccatttt
     5041 tgtctcaata tgaaacaact tggttacttc caattttagg gcaaattcat gtaagtacaa
     5101 taacactttt tgaattaggt attttattct cagttgttgg tgttattgtc acagtgatgt
     5161 tgtcgcttag cggaggtcga tcatgaattt aatattatta ctagttatag gatttttagt
     5221 gtttatagga acatatatga ttttatcaat caatttaatt cgtattgtaa ttggaatttc
     5281 aatatatact catgctggta atctcattat tatgagtatg ggaacgtatg gttctagtag
     5341 atcagaacca ttaataactg gtggaaacca attgtttgtt gatcccttgt tacaagctat
     5401 tgtactaact gcaatagtta tagggtttgg gatgactgcg tttttacttg tacttgttta
     5461 tagaacttat aaagtaacaa aagaagatga aattgaaggc ctaagggggg aagatgatgc
     5521 taagtaactt attgatttta ccaatgttat taccattcct ttgtgcctta atccttgtat
     5581 ttttaaaaaa taatgatcgt atttctaaat atttatactt aggtacaatg actatcacca
     5641 caattatttc attaatgtta ttaatttatg ttcagcgtca ccgtccaatt acgctagact
     5701 ttggaggatg gtcagcgccc tttggtatac agtttttagg agattcttta agtttaatta
     5761 tggttacaac cgcttcattt gtgattactt taattatggc atacggattt gggcgtggcg
     5821 aacataaagc aaatcgttat cacttgccat cgttcatatt atttttaagc gttggcgtga
     5881 taggctcttt tctaacatca gatttattta atttatacgt catgtttgaa attatgttac
     5941 ttgcgtcatt tgtactcatt acacttggac aatctgttga acaattacgt gccgcaatta
     6001 tttatgttgt cttgaatatt attggttcat ggctattctt attaggtata ggtttacttt
     6061 ataaaacagt aggtacatta aacttttcac atattgcaat gcgtttgaat gatatgggag
     6121 ataatcgcac tgtaacaatg atttcattaa tcttcttagt cgcatttagt gcgaaagcag
     6181 cgctggttct ttttatgtgg ctacccaaag catacgcagt gttaaatact gagcttgcag
     6241 cattatttgc agcgttaatg accaaagtag gggcctatgc attaattcga ttcttcactt
     6301 tactattcga tcaacataat gatctcatac atccattgct agcaactatg gctgctataa
     6361 ctatggtcat cggcgctata ggtgtcattg cttataaaga tattaaaaag attgcagctt
     6421 accaagtcat aatctcaata ggatttatca ttttaggttt gggaacaaac acgtttgcag
     6481 gtattaatgg tgcaatattt tatttggtaa atgacattgt tgtaaaaaca ttgctattct
     6541 ttattattgg tagtttagtt tacattacag gctatcgaca atatcaatat ttgaatggct
     6601 tagctaaaaa agaaccttta tttggagttg cgtttattat aatgattttt gctattggcg
     6661 gcgtgccccc atttagtggc tttccgggga aagtacttat tttccaaggc gcattgcaaa
     6721 atggcaatta tattggacta gcgttaatga ttattactag tctaattgca atgtacagtt
     6781 tatttaggat acttttttat atgtattttg gagataaaga tggggaggaa gttaatttta
     6841 agaaaatccc actatatcga aaaagaattt taagtatttt agtagttgtg gttatcgcaa
     6901 tcggaattgc tgcgcctgta gtgttaaatg ttacaagtga tgcaactgag ttgaacacga
     6961 gtgatcaatt atatcaaaaa cttgtaaatc cgcatttgaa aggagaggac taaatgaatc
     7021 aaatagtttt aaatattatc attgcattct tatgggtatt atttcaagat gaagatcatt
     7081 ttaaattctc gactttcttt tctggatatc taattggtct aattgtcatt tatatattac
     7141 acaggttttt cagcgatgat ttttatgtta gaaaaatttg ggtagctatt aaatttttag
     7201 gtgtttattt atatcaatta ataacatcta gcattagcac gattaattat attcttttta
     7261 aaacaaaaga tatgaaccct ggattacttt catatgaaac aagactaaca agtgactggg
     7321 caataacatt tttaacaatt ttaattatta taactccagg gtctacagta atacgaattt
     7381 ctcaagactc taaaaagttt tttattcata gtatcgacgt gtcagaaaaa gaaaaagata
     7441 gtttgttaag aagtattaag cattatgaag acttaatatt ggaggtgtcg cgatgataca
     7501 aacaataaca catattatga ttattagttc actcattatt tttggaattg cattaatcat
     7561 ctgtttattt agattaatca agggacctac aacagcagat cgtgtcgtta catttgatac
     7621 aacaagtgct gtcgtaatgt caattgtggg tgtgttaagt gtacttatgg gcaccgtttc
     7681 tttcttagat tcaatcatgc tcattgccat tatatctttt gtaagttctg tttcaatatc
     7741 acgctttatt ggtggggggc atgtgtttaa tggaaataac aaaagaaatc tttagtctta
     7801 ttgctgctgt gatgttgttg ttaggtagtt ttattgctct tattagtgca ataggtatcg
     7861 tgaaattcca agatgttttc ttaagaagtc acgctgcgac aaaaagttca actttatcag
     7921 tgttattaac tttaatcggt gtattaattt attttattgt gaatacagga tttttcagtg
     7981 tgcgtttatt actgtcactt gtttttatta atttaacttc acccgtcggc atgcacttag
     8041 tcgctcgcgc tgcttatcgc aacggcgctt atatgtatcg aaaaaatgat gatcacacac
     8101 atgcatcaat attattaagt tcaaatgaac aaaactctac agaagcatta caattacgtg
     8161 ctaaaaaacg agaagagcat cgtaagaaat ggtatcaaaa cgattgaagt gttggctaaa
     8221 ttgttaagca taacgatgct tttgaagatt tgttttcaaa attaatcatt aaaagagtac
     8281 tttgaaattg gttagtcgat tttaaggtgc tcattttttg tattataagt taatgttgtt
     8341 atgtgaaagc aagttgttta tttatacaaa caattagtga taaaataaaa ttaaataatt
     8401 gcaaatttaa gtactgcaat cgtagacata tatctatatt aaagtgcttt tgtggtcgct
     8461 aactcaattt atcctctaaa gtataattac aacgagatgt gatacttaat tttcaattaa
     8521 acaatacttt ttagagaggt gaaagtttgg aaatatttga aacaattctt atatttatag
     8581 ctgttgtgat actaagttcg tttgtccata ctttcatacc taaagtaccc ctagcattta
     8641 tacaaatttt cttgggcatg ttactattta ttaccccaat ccctgttcaa tttaattttg
     8701 attctgaatt gtttatggta acaatgattg cgcctttgtt atttgtagaa ggtgttaatg
     8761 tttctagagt ccatttaaga aaatatatta agccagtgat gatgatggca ttaggattag
     8821 tcattactac tgtgataggt gtaggtttat ttattcattg gatttggcca gatttaccta
     8881 ttggagcagc atttgcaatt gctgccattc tttgccctac tgatgcagta gcagtgcaag
     8941 caatcactaa aggaaaggtc ttgccaaaag gagcaatgac aattcttgaa ggtgagtcat
     9001 tattgaatga tgctgctggt attatttcat ttaaaatagc tgttggagta ttagttacag
     9061 gtgctttttc acttgttgat gctgttcagt tgtttttaat tgcatcaatt ggtggcgcag
     9121 tggttggttt acttataggt atggcattag taaggttccg attaacattg atgcgtcgag
     9181 gatatgaaaa cattaatatg tttacaatta ttcaattgtt aacaccattt gttacgtatt
     9241 taattgctga attgtttcac gcatcaggaa tcattgcagc agtagttgca ggacttgtac
     9301 atggtttcga acgtgacaga attatgcaag tacgtacaca actacaaatg agttacaatc
     9361 atacatggaa tatactaggt tatgttttaa atggctttgt tttttcaata ttaggatttt
     9421 tagtacctga agttattatt aaaattatca aaacagaacc gcacaattta atctttttaa
     9481 taggcatcac tattgttgtt gctttagctg tctatctatt tagatttgtt tgggtttatg
     9541 tcttatatcc ttatttttat ttagccatca gtccattcca aaaaatgatg actaaaaatg
     9601 atgatgataa tccaacgact gagaaaccac caaagcgaag tttatacgct ttaattatga
     9661 cgttatgtgg tgtgcatgga acaatttctt tagcaatcgc attaacgtta ccgtattttt
     9721 tagcagggca tcatgctttt acgtatagaa acgacttatt atttattgca tctggtatgg
     9781 ttattattag tttggtagtt gcgcaagtat tattgccact attaacgaaa cctgcaccta
     9841 aaacagtaat tggcaatatg tcgtttaaag ttgctagaat ttatatatta gaacaagtta
     9901 ttgattatct aaatcaaaaa tctactttcg aaacaagttt taaatatggt aacgtgatta
     9961 aagaatatca tgataaatta gcatttttaa aaactgtaga gaaagatgat gaaaactcta
    10021 aagaattaga acgtctacaa aaaattgctt ttaatgtaga aacaaaaaca ttagagtctt
    10081 tagtagatga aggacaaata acgaatagtg tacttgaaaa ctatatgcgt tatgctgaaa
    10141 gaacacaagt atatagacaa gcatcattaa taagaagaat gattgtatta ttacgaggtg
    10201 ctttattaaa acgaagagta caaacgagag tgaactcggc atcttcactt agtgttacgg
    10261 ataacttaat ggaattaaat aaaattaata aattagtcca ttataatgtg gttagtcgat
    10321 tgtctaagga aacaacaaaa gataatacac ttgaagttgg aatggtttgt gacggttatt
    10381 taatgcgaat tgaaaactta acaccatcta atttcttcaa ctcagcaagt gaagatacga
    10441 ttactaaaat taaattaaat gcattgagag aacaacgtcg cattttacgt gagttgattg
    10501 atacagatga agtatcagaa ggtacagcgt taaaactaag agaggccatt aattatgatg
    10561 aaatggttat tgtagatagt atgacgtagt tcgtaattat gctaaaaggg attgatgaaa
    10621 aaatgaatgg cttttcatca atccctttta ttttagggga attgaataga tagttttaaa
    10681 ctatacgaat tattaatatt tgagaattaa ttgaaataag ttttaaaaat tggaggagat
    10741 agattaatcg aagtcattta aattaagaag atacgtgcat tcacaaaaaa tagccacact
    10801 catatgacat cggatgagtg tggcttaagg atctatgggg ggaggaaacc atagatgttt
    10861 actttgatag gccagattaa atatcaaagt atgcgattat ttatagcttg atgcaaaagt
    10921 ggtatgccta ttaaaagtta ctgcacatag cttttaatat tccgttcaaa ggaaaggggc
    10981 atacaattga acaatctgta atagtacttt taaccagcta tgctaaaagt ctagtaggga
    11041 gaacagttgt ccaatcacat aagaacctct aacttcgtta gtacgattaa gaaaagcttt
    11101 ttagttagta tgtaatacaa tttattgacg cgcgtgaatc tcttttataa gagtgtgtag
    11161 ggaatggcgt tgtataaatt gtattagaag aacttctaac gcatctctgt ggttaaaaga
    11221 gatgaaggga acgacagttt aattaaaact gcataagaac ttctagcttt tctctttcgt
    11281 tcaaagagaa gttctaatac caccatatcg tgcgatcggg aacggtatat atattaatag
    11341 gagggtaata tatatttaac gcacgatatg ggactattag ccttcgactt tgttatgttg
    11401 atgtgtggcc taaaatattg gagataccaa tattttaggt tgcatcaaca tcaattcatc
    11461 ttacttcatt aaaacacagc gtgttatttc atgcttccgt gtacagtatc aatatttgat
    11521 ttcatcattt tgtagtaaga gtcaccttta gtgccttctt taccgattga atctgtgtac
    11581 acttcaccaa agatatcttt cttcgtttct tcagataaac tttccattgc tttcttatca
    11641 acacttgttt ctactaataa gtgttttaat ttgtgctttt taacaaactc aatagcttgt
    11701 ctcatttgtt caggtgtacc ttgtttttca gtgttaattt cccaaatata acctggtgta
    11761 ataccgtatt gttttgagaa gtacttgaag gcaccttcac ttgtaatcat ggcacgttgt
    11821 tcttttggaa tgtcattaaa tttgtcttta ctgtcattat ttaatttttc caattgagca
    11881 atgtatttgt taccttgctt ttcataatct gctttatgtt ttttgtcgtt atcgataaat
    11941 gtttgttgaa ttgtttttac gtatttaata ccgttatcta aacttaacca tgcgtgtgga
    12001 tcttgtttat ctttgttgcc ttcttcaccg tttaaataga taggtttaac atcttttgat
    12061 actgcgataa cttttttatc ttttaatgat ttaccagcct gttctaaggc tttttcaaac
    12121 caaccgttac cagtctctaa atttaatccg ttgtataaaa taacgtcagc gtcagttaac
    12181 tttttaatat ctttaggttt aacttcatat tcatgaggat cttgaccaac aggtacaata
    12241 ctatgaatat cgacgttgtc tccaccaaca tttttagcca tatcatataa aattgaattc
    12301 gtcgttacta cttttaattt gccatttgac ttatcactgc tttgtttacc accagtacca
    12361 catgcagcaa ctagaagtaa taaggctaat aataaaggta ctaatttttt catgttaaac
    12421 ttcctcgttt ctttctattc gtaaattttg tgaaaaataa tgtgatgata taaattacaa
    12481 acgtacaaag tacgattgtc gcaccactag gaatgttgta aatatagctg taataaagtc
    12541 cgacaattga acttatgaca cttattaaac ttgctataat catcattgag tatagttttt
    12601 tactaattaa aaatgctgta gatgcaggtg taattaataa tgcaactaca agaataatac
    12661 ctaccgtttg aatacttgct actgttacta atgagagtaa caacatcaca aagtaatgta
    12721 ataacgtcgt atttagacca ctcattctac taaacgttgg atcgaatgta gaaatcatta
    12781 atggacgata gaaaataatg attagaataa ggacgattga accaatcaca atagttgtta
    12841 aaaatgcact atttgtgatt gccagtaaat taccaaacag aatatggtac aaatctgtcg
    12901 tagtgtttat taagctaata ataataatcc ccgaagctaa gaaagcggta aaactaattc
    12961 caatagcggc gtcaggtttc gttttactac tagatgtgat ataaccgata aaaatacttg
    13021 cgatcatacc agttataagt gcgcctacaa acattggaat accaaataag aatgataggg
    13081 caacaccagg taatactgcg tgactcattg catctcccat taatgaaaga ccacgtaata
    13141 caattaaact accaactgta ccacaaacta tccctacaat aattgaagtt atcaatgctc
    13201 gattcaagaa ttgatatgta aataaatgtt cgacaaactc taacatgtta tattgctcct
    13261 ttgactaggg tcactacagt cagtgctact cataaatgtt tcgtttaagc gagtgacact
    13321 catagcctct tcactatcac cgaagtatcg taatgtttga tttaatagaa taatgcgatc
    13381 aaagtattgc tttgcttttg atagatcatg gtggatgata agaataagtt ttccttgttg
    13441 ttttaagttc tcgatttttg tcatgattaa tttttcgcta ctaaaatcaa ttccgacaaa
    13501 cggctcatct agaaaataaa cttcactttc ggacatcaat gctcttgcta ctagcacacg
    13561 ttgtaattgt ccaccactta attctgaaat ttgtcgatga cgtaaagatt ctaattctaa
    13621 atcgcttaat aactgtttga gtttatccct tgctgattta ttaggtcgtc taaaccatcc
    13681 aatttctttg tagcaacctg ataaaatcac ttgttccaca cttataggaa aatctaaatc
    13741 aatatgtgct ttttgtggaa tatatgtaat atgttgcagt tgttgttgta taggtttgtt
    13801 atataacaat ttagtaccgg tagcattaaa ttcaccaatt aaagacttga taagggaaga
    13861 tttaccagca ccattcgggc ccatgatacc aattatttcg ccgcgtactg gtatcgataa
    13921 ggaaatgttt ttaagtacat gcttattacc taaaaacaga tttaaatctt ttgtttctaa
    13981 caaacgttta tacctcctaa ttaaaagttt aggctaacct aattaattgt ataataaact
    14041 gagaatattt atcatgtcaa gtaaattcgt gatataatat agacaatgta tgtgaggtga
    14101 aagtatgtta actgaagaaa aagaggacta tttaaaggca atccttacga ataatggcga
    14161 taaaaacttt gtgacaaata aaatcttatc tcaattttta aatattaagc ctccatctgt
    14221 aagtgaaatg gtaggacgtc ttgaaaaagc aggctatgtt gaaacaaaac catacaaagg
    14281 tgttagatta acagaggatg gtttaacgca tacgcttgat atcattaaga gacatcgact
    14341 attagaatta tttttaatag aaatattgaa atataattgg gaagaagtac atcaagaagc
    14401 agaaatttta gaacatcgaa tttcagattt atttgttgaa aggctggata gcctgttaaa
    14461 tttcccagaa acttgcccgc acggcggtgt gattcctaga aataatgaat ataaagagaa
    14521 atatataaca acgattttga attatgaacc tggtgatatc gttacaatca aacgtgtgag
    14581 agataagacc gatttgctaa tatatttgtc tagtaaagat atttctattg gtaatgaagt
    14641 ggaaattgta tcgaaagatg aaatgaataa agtaattatt attaaacgta atgataatgt
    14701 aattattgtc agttacgaaa atgcaatgaa catgtttgct gaaaaataaa ataaagaagc
    14761 cataaagata tccatgattg tactgataaa gacatatgga taattgcttt aggcttcttt
    14821 tttattagtt aatttatcaa gtgagtatat ttgagtaaaa tattcactgc ataaagattg
    14881 aagataatcc agattgtact ataaatgaag ataggtacat gactgagttc tttaagtgca
    14941 ctaccatccc actgtggact cggacgctgg aaagtcaatt tagcaatcgt ccaactagat
    15001 tgtagaactt cgcctaataa tacacctaaa atatattgat aactcattgt gacaagtagt
    15061 tgaatttcta ctatattttc atcttttaat ataaaataca acatgataga aattaaagtt
    15121 ataacaacaa tgggtgagcc ttttctagat gttaaaatta aaaaataaat aaatatcaat
    15181 aagtaggtaa atataaagaa actaggtatc tgataatggc tcgacgctaa acctatcaat
    15241 aacataatag gtggcataaa ataaccacca atcgttgtaa gccattggcc tgctagatgt
    15301 ctagattgtg taattgcgaa tccttgttgt aatgtctgtt gtcgctctcg tggacttgtt
    15361 acaatgacta aatcttttgc acggccacca gcgagtttat taaacaatac atgaccaaat
    15421 tcatgtgtta aaacagggat atagtttaaa atgacatcta aatagttcaa aacagcctta
    15481 tgtctatatt gatgaatagc aatataacaa gctgcaacaa taacgataat gtatatatta
    15541 agttgaattg tcgtattaaa aaagtttgat aaataattca ttgttaacct catataagat
    15601 attaatttaa agtttgctta tcacttatta taaatgatat tggcattaat agcgttagac
    15661 tttagactta ccttagttaa actaatttta atttttgaaa aggtgaatat gtgttaaaat
    15721 aaagcaaaat c
//
LOCUS       DAPSKH010000062        15699 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPSKH010000062 DAPSKH010000000
VERSION     DAPSKH010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15699
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.062"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            29..1639
                     /locus_tag="RPH49_002186"
     CDS             29..1639
                     /locus_tag="RPH49_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MutS family DNA mismatch repair protein"
                     /protein_id="HDY5125311.1"
                     /translation="MSTNQTFLIFVIAIILLTSVIGIVGRYMSRQRLLKSMETLWQTI
                     SPLEAFIRPNSHFDYEYKLYKEKFESHSLVDDKTWSDLNMNAIFHKMNYNLTAIGEMK
                     LYACLRGMLSITNKSLLSLFNDNAEFRKNVTYHLALVGKTVYPTFPDQITPVKRQNIL
                     FLCPFLPVISFAVIFINSQVGILLFLMSCLFNIILSATLKRTYEDDLKSIFYASNVLK
                     QGYTISKIKHAPQPEVNFKQFRTARHLTSVLAEVNDEDIGAMVIKLVKLIFMLDYVLF
                     HSIQKSYTTHMNELKNCFDYIAELDNHYALAMYRRTLECYTEPQIDDSNDGIVFSELT
                     HPLIADAVANDFSLSQNILLTGSNASGKSTFMKSIAINIILASAIQTVTASKFVYQPG
                     IVFTSMANADDVLSGDSYFMAELKSIKRIVEIPDNQKIYCFIDEIFKGTNTTERIAAS
                     ESVLSFLHEKSNFRVIAATHDIELAELLKQRYENYHFNEVIENNNIHFDYKIKPGKAN
                     TRNAIELLKITSFPTKIYERAKDNVPKI"
     gene            complement(1741..2766)
                     /gene="tsaD"
                     /locus_tag="RPH49_002187"
     CDS             complement(1741..2766)
                     /gene="tsaD"
                     /locus_tag="RPH49_002187"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDY5125312.1"
                     /translation="MTKDILILAVETSCDETSVSVIKNGRDILSNTVLSQIESHKRFG
                     GVVPEVASRHHVEGITTTINEALVDADVSMEDIDAIAVTEGPGLIGALLIGVNAAKAL
                     AFAYDKPLIPVHHIAGHIYANHIEEPLTFPLIALIVSGGHTELVYMKDHLSFEVIGET
                     RDDAVGEAYDKVARTIGLNYPGGPQVDRLAAEGEDTYSFPRVWLDKDSYDFSFSGLKS
                     AVINQLHNQRQKNIPIIEANVATSFQNSVVEVLTFKAIQACKKYGVQRLIVAGGVASN
                     KGLRQSLADQCKVNDIQLTIPSPKLCTDNAAMIGVAGHYLYQQGRFADLALNGHSNID
                     LEEYSAE"
     gene            complement(2759..3223)
                     /gene="rimI"
                     /locus_tag="RPH49_002188"
     CDS             complement(2759..3223)
                     /gene="rimI"
                     /locus_tag="RPH49_002188"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDY5125313.1"
                     /translation="MDQQSKEQLNIREMTKEDVPQVFDIERRSFNDSSWTIDAFYHEI
                     EQNNFAKYFVLEFEQQIIGYLGLWIVIDQAQITTVAIDDNYRGYGLGQMLLKYGINYA
                     SHTCDVMSLEVRVNNKVAQHVYENLGFQYGGKRKNYYGEGEDAMVMWVNLND"
     gene            complement(3196..3858)
                     /gene="tsaB"
                     /locus_tag="RPH49_002189"
     CDS             complement(3196..3858)
                     /gene="tsaB"
                     /locus_tag="RPH49_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDY5125314.1"
                     /translation="MNSLLIDTSNQPLSVALMQNDEVLAEITTDSKQNHSVQLMPAIS
                     QLFEQSKIAKQQLDAIIVAEGPGSYTGLRIGVTVAKTLAYALDVKLYGVSSLKALAAT
                     IDHTDKLLVPVFDARRQAVYTGIFQWQNGQLVTILEDQYMSIEALRAFLEDLNQPFIY
                     IGKDTVKLQDELQGDVIAQLPNASVMHQLIDKPSDVHTFTPKYHKLAEAERNWINSQK
                     NN"
     gene            complement(3839..4300)
                     /gene="tsaE"
                     /locus_tag="RPH49_002190"
     CDS             complement(3839..4300)
                     /gene="tsaE"
                     /locus_tag="RPH49_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDY5125315.1"
                     /translation="MIKINNLDEMNQFAMFLVEQLKSGDLILLNGDLGAGKTTLTQFI
                     GKALGVRRTINSPTFNIIKSYRGKNLKLHHMDCYRLEDSDEDLGFDEFFEDQAITVIE
                     WSQFIKDLLPSTHLSINISTISENTRQIELFAQGEHYEQIKEAIIHEFAAH"
     gene            4338..4493
                     /locus_tag="RPH49_002191"
     CDS             4338..4493
                     /locus_tag="RPH49_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125316.1"
                     /translation="MIIHCSIVSNFIFNLYIVTNFNLNFLSLKQIISSKLIVRKFKIF
                     IDILKQI"
     gene            4811..6499
                     /gene="ilvD"
                     /locus_tag="RPH49_002192"
     CDS             4811..6499
                     /gene="ilvD"
                     /locus_tag="RPH49_002192"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDY5125317.1"
                     /translation="MRSDMIKKGDHQAPARSLLHATGALKSPTDMNKPFVAICNSYID
                     IVPGHVHLRELADIAKEAIREAGAIPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADA
                     AETVINAHWFDGVFYIPNCDKITPGMILAAMRTNVPAIFCSGGPMKAGLSAHGKALTL
                     SSMFEAVGAFKEGSISKEEFLDMEQNACPTCGSCAGMFTANSMNCLMEVLGLALPYNG
                     TALAVSDQRREMIRQAAFKLVENIKNDLKPRDIVTREAIDDAFALDMAMGGSTNTVLH
                     TLAIANEAGIDYDLERINAIAKRTPYLSKIAPSSSYSMHDVHEAGGVPAIINELMKKD
                     GTLHPDRITVTGKTLRENNEGKEIKNFDVIHPLDAPYDAQGGLSILFGNIAPKGAVIK
                     VGGVDPSIKTFTGKAICFNSHDEAVEAIDNRTVRAGHVVVIRYEGPKGGPGMPEMLAP
                     TSSIVGRGLGKDVALITDGRFSGATRGIAVGHISPEAASGGPIALIEDGDEITIDLTN
                     RTLNVNQPEDVLARRRESLTPFKAKVKTGYLARYTALVTSANTGGVMQVPENLI"
     gene            6527..8296
                     /gene="ilvB"
                     /locus_tag="RPH49_002193"
     CDS             6527..8296
                     /gene="ilvB"
                     /locus_tag="RPH49_002193"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic-type acetolactate synthase large
                     subunit"
                     /protein_id="HDY5125318.1"
                     /translation="MSKTQHEVNQNIDPLKMAESLEPEQLNEKTLNDMRSGSEVLVEA
                     LLKENVDYLFGYPGGAVLPLYDTFYDGKIKHILARHEQGAVHAAEGYARVSGKTGVVV
                     VTSGPGATNVMTGITDAHCDSLPLVVFTGQVATPGIGKDAFQEADILSMTSPITKQNY
                     QVKRVEDIPKIVHEAFHVANSGRKGPVVIDFPKDMGVLATNVDLCDEINIPGYEVVTE
                     PENKDIDTFISLLKEAKKPVVLAGAGINQSKSNQLLTQFVNKHQIPTVTTLLGLGAVP
                     YEDTLFLGMGGMHGSYASNMALTECDLLINLGSRFDDRLASKPDAFAPNAKIVHVDID
                     PSEINKVIHADLGIIADCKRFLECLNDKNVETIAHSDWVKHCQNNKQKHPFKLGEKDP
                     VFCKPQQTIEYIGKITNGEAIVTTDVGQHQMWAAQFYPFKNHGQWVTSGGLGTMGFGI
                     PSSIGAKLANPDKTVVCFVGDGGFQMTNQEMALLPEYGLDVKIVLINNGTLGMVKQWQ
                     DKFFNQRFSHSVFNGQPDFMKMAEAYGVKGFLIDKPEQLEEQLDAAFAYQGPALIEVR
                     ISPTEAVNPMVPSGKSNHEMEGL"
     gene            8296..8550
                     /locus_tag="RPH49_002194"
     CDS             8296..8550
                     /locus_tag="RPH49_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HDY5125319.1"
                     /translation="MTRILKLQVADQVSTLNRITSAFVRLQYNIDTLHVTHSEQPGIS
                     NMEIQVDIQDDTSLHILIKKLKQQINVLTVECYDLVDNEA"
     gene            8688..9692
                     /gene="ilvC"
                     /locus_tag="RPH49_002195"
     CDS             8688..9692
                     /gene="ilvC"
                     /locus_tag="RPH49_002195"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDY5125320.1"
                     /translation="MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVV
                     IGIRPGRSFDKAKEDGFDVFPVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNA
                     LAFAHGFNIHFSVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQDASGQA
                     RNIALSYAKGIGATRAGVIETTFKEETETDLFGEQAVLCGGVSKLIQSGFETLVEAGY
                     QPELAYFEVLHEMKLIVDLMYEGGMENVRYSISNTAEFGDYVSGPRVITPDVKENMKA
                     VLTDIQNGNFSNRFIEDNKNGFKEFYKLREEQHGHQIEKVGRELREMMPFIKSKSIEK
                     "
     gene            9722..11251
                     /locus_tag="RPH49_002196"
     CDS             9722..11251
                     /locus_tag="RPH49_002196"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDY5125321.1"
                     /translation="MSSHIQIFDTTLRDGEQTPGVNFTFDERLRIALQLEKWGVDVIE
                     AGFPASSTGSFKSVQAIAQTLTTTAVCGLARCKKSDIDAVYEATKDAAKPVVHVFIAT
                     SPIHLEHKLKMSQEDVLASIKEHVTYAKQLFDVVQFSPEDATRTELPFLVKCVQTAVD
                     AGATVINIPDTVGYSYHDEYAHIFKTLTESVTSSNEIIYSAHCHDDLGMAVSNSLAAI
                     EGGARRIEGTVNGIGERAGNAALEEVALALYVRNDYYGAQTALNLEETKKTSDLISRY
                     AGIRVPRNKAIVGQNAFSHESGIHQDGVLKHRETYEIMTPQLVGVSTTELPLGKLSGK
                     HAFSEKLKALGYDIDKEAQIDLFKQFKAIADKKKSVSDRDIHAIIQGSEHEHQALYKL
                     ETLQLQYVSSGLQSAVVVVKDKEDHIYQDSSIGTGSIVAIYNAVDRIFQKETELIDYR
                     INSVTEGTDAQAEVHVNLLIEGKTVNGFGIDHDILQASCKAYVEAHAKFAAENVEKVG
                     N"
     gene            11254..12300
                     /gene="leuB"
                     /locus_tag="RPH49_002197"
     CDS             11254..12300
                     /gene="leuB"
                     /locus_tag="RPH49_002197"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDY5125322.1"
                     /translation="MTYNIVALPGDGIGPEILNGSLSLLEIISNKYNFNYQIEHHEFG
                     GASIDTFGEPLTEKTLNACKRADAILLGAIGGPKWTDPNNRPEQGLLKLRKSLNLFAN
                     IRPTIVVKGASSLSPLKEDRVEGTDLVIVRELTSGIYFGEPRHFNNHEALDSLTYTRE
                     EIERIVHVAFKLAASRRGKLTSVDKENVLASSKLWRKVVNEVSQLYPEVTVNHLLVDA
                     CSMHLITNPKQFDVIVCENLFGDILSDEASVIPGSLGLSPSASFSNDGPRLYEPIHGS
                     APDIAGKNVANPFGMILSLAMCLRESLNQPDAADELEQHIYNMIEHGQTTADLGGKLN
                     TTDIFEILSQKLNH"
     gene            12314..13684
                     /gene="leuC"
                     /locus_tag="RPH49_002198"
     CDS             12314..13684
                     /gene="leuC"
                     /locus_tag="RPH49_002198"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDY5125323.1"
                     /translation="MGQTLFDKVWNRHVLYGKLGEPQLLYIDLHLIHEVTSPQAFEGL
                     RLQNRKLRRPDLTFATLDHNVPTIDIFNIKDEIANKQITTLQKNAIDFGVHIFDMGSD
                     EQGIVHMVGPETGLTQPGKTIVCGDSHTATHGAFGAIAFGIGTSEVEHVFATQTLWQT
                     KPKNLKIDINGTLPTGVYAKDIILHLIKTYGVDFGTGYALEFTGETIKNLSMDGRMTI
                     CNMAIEGGAKYGIIQPDDITFEYVKGRPFADNFAKSVDKWRELYSDDDAIFDRVIELD
                     VSTLEPQVTWGTNPEMGVNFSEPFPEINDINDQRAYDYMGLEPGQKAEDIDLGYVFLG
                     SCTNARLSDLIEASHIVKGNKVHPNITAIVVPGSRTVKKEAEKLGLDTIFKNAGFEWR
                     EPGCSMCLGMNPDQVPEGVHCASTSNRNFEGRQGKGARTHLVSPAMAAAAAIHGKFVD
                     VRKVVV"
     gene            13685..14257
                     /gene="leuD"
                     /locus_tag="RPH49_002199"
     CDS             13685..14257
                     /gene="leuD"
                     /locus_tag="RPH49_002199"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDY5125324.1"
                     /translation="MAAIKPITTYKGKIVPLFNDNIDTDQIIPKVHLKRISKSGFGPF
                     AFDEWRYLPDGSDNPDFNPNKPQYKGASILITGDNFGCGSSREHAAWALKDYGFHIII
                     AGSFSDIFYMNCTKNAMLPIVLEKNAREHLAKYVEIEVDLPNQTVSSPDKSFHFEIDE
                     TWKNKLVNGLDDIAITLQYESLIEKYEKSL"
     gene            14272..15540
                     /gene="ilvA"
                     /locus_tag="RPH49_002200"
     CDS             14272..15540
                     /gene="ilvA"
                     /locus_tag="RPH49_002200"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HDY5125325.1"
                     /translation="MTVKTTVSTKDIDEAFLRLKDIVKETPLQLDHYLSQKYDCKVYL
                     KREDLQWVRSFKLRGAYNAISVLSDEAKSKGITCASAGNHAQGVAYTAKKLNLNAVIF
                     MPVTTPLQKVNQVKFFGNSNVEVVLTGDTFDHCLAEALTYTSEHQMNFIDPFNNVHTI
                     SGQGTLAKEMLEQAKSDNVNFDYLFAAIGGGGLISGISTYFKSYSPNTKIIGVEPSGA
                     SSMYESVVVNNQVITLPNIDKFVDGASVARVGDITFEIAKKNVDNYVQVDEGAVCSTI
                     LDMYSKQAIVAEPAGALSVSALENYKDHIKGKTVVCVISGGNNDINRMKEIEERSLLY
                     EEMKHYFILNFPQRPGALREFVNDVLGPQDDITKFEYLKKSSQNTGTVIIGIQLKDDD
                     DLIQLKQRVNHFDPSNIYINENKMLYSLLI"
BASE COUNT         5307 a         2672 c         2776 g         4944 t
ORIGIN      
        1 attattcaaa ataaataagg agatacttat gagcacaaat caaacatttt taatatttgt
       61 tatagcaatt attctactta catctgtaat aggaattgtt ggacgataca tgagtcgtca
      121 acgtctatta aaatctatgg aaacattatg gcaaacgatt tctccattag aagcttttat
      181 cagaccgaac tcacatttcg actatgagta taagctctac aaggaaaaat ttgaatcaca
      241 ttcattagtt gatgataaaa cttggtccga cttaaatatg aatgcaatct ttcataagat
      301 gaattataat ttaacagcta ttggtgaaat gaagctatat gcctgtttac gtggaatgct
      361 ttcaattacg aacaaatcat tacttagttt atttaatgat aatgctgaat ttagaaaaaa
      421 cgtaacatat catttagctt tggttggtaa aactgtttat ccaacatttc cagaccaaat
      481 cacaccggta aaacgtcaaa atatattgtt tctatgccca tttttaccag ttatctcatt
      541 tgcagttata tttattaatt cacaagttgg tattttatta tttcttatga gttgcctatt
      601 taatatcatt ttatctgcaa ctttaaagcg tacatatgag gatgacttaa agtctatctt
      661 ttatgcatcc aatgttttaa aacaaggcta tactatctca aaaattaaac atgctccaca
      721 acccgaagtc aattttaagc aatttagaac agcacgtcat ttaacgagtg ttttagctga
      781 agttaatgat gaagatattg gagctatggt aattaaacta gttaaactta ttttcatgct
      841 tgattatgtt ttattccatt caattcaaaa aagctataca acacatatga atgagctaaa
      901 aaattgtttc gattacatag ctgaattaga taatcattat gcattagcaa tgtatcgtag
      961 aacgctagaa tgctatactg aaccacaaat tgatgattca aatgatggca tagtattctc
     1021 tgagttaaca catccactca tagcagatgc agtagccaat gatttctcac tatcacaaaa
     1081 tatactgtta actgggtcta atgcttcggg taaatcaaca tttatgaaat ccatagcaat
     1141 aaacattatt cttgcatcgg ctatacaaac agttaccgca agcaaatttg tatatcaacc
     1201 tggaattgtg ttcacgtcaa tggcaaatgc cgatgatgtg ttatcaggcg atagttattt
     1261 tatggctgaa ttaaaatcta ttaagcgtat tgttgaaatt ccagacaatc aaaaaatata
     1321 ctgctttata gatgaaattt ttaaaggtac caacacaact gaacgaattg ccgcttcaga
     1381 atcagtacta tcatttttac atgaaaaatc taactttaga gttattgcag caacacatga
     1441 tattgagtta gctgaactct taaaacaacg ttatgaaaat tatcatttca atgaggtaat
     1501 agaaaataat aacatacatt ttgattacaa aattaagcct ggcaaagcaa atacacgtaa
     1561 tgccatcgaa ttattaaaaa tcacttcatt tccaacaaaa atatatgaac gagcaaaaga
     1621 taatgtcccg aaaatttagc atttaacttt aaacataaaa acgtcagcta tcacatgaca
     1681 gaagactatg aacagtttca ataatgttca tcgtaatcat gttaataact gacgtttatt
     1741 ttattctgca gaatactctt ctaaatctat attgctgtgc ccatttaatg ctaaatcagc
     1801 aaatcgacct tgctgataca aatagtggcc ggcaacgcct atcattgcag cattatctgt
     1861 gcataattta ggacttggga tagttaattg aatgtcattg actttgcatt gatccgctaa
     1921 agattgacgt aatcctttat tactcgccac gccaccagca acaattaatc gctgaacacc
     1981 atatttttta caagcttgaa tagctttaaa cgtaagcacc tctacaacac tgttttgaaa
     2041 gctcgttgct acgttagctt caatgattgg aatatttttt tgtcgttgat tgtgaagttg
     2101 attgattacg gcacttttca acccactaaa actaaaatca taactatctt tatccaacca
     2161 aacacgaggg aatgaataag tatcttcacc ttcagcagcc aaccgatcaa cttgtggacc
     2221 acctggataa tttaaaccaa ttgttcgtgc cactttatca taagcttcac ctactgcgtc
     2281 atctcgtgtt tcaccaatga cttcaaatga taaatgatct ttcatataaa ctaattcagt
     2341 atgtccacct gaaacaataa gtgcaattag cgggaatgtt aatggctctt ctatgtgatt
     2401 agcatatata tgtcctgcaa tatgatgaac aggaataagt ggcttatcgt aagcaaatgc
     2461 caatgctttg gctgcattaa cacctattag taacgcacca attagtccag ggccttctgt
     2521 aaccgctatg gcatcaatat cttccattga tacatcggca tccactagag cctcgtttat
     2581 tgttgttgtt ataccttcaa cgtgatgtct acttgccact tcgggaacga caccgccaaa
     2641 tcgtttatga ctttcaatct gacttaaaac tgtatttgat aaaatatctc tgccattttt
     2701 tataacacta acgcttgttt catcacaact tgtttcaaca gctagtatta atatatcttt
     2761 agtcatttaa attcacccac ataaccattg cgtcctcacc ttcaccataa taatttttac
     2821 gtttaccacc atattgaaat cctaaatttt catatacatg ttgtgccact ttattattaa
     2881 ctcttacttc taaactcatc acatcacaag tgtgacttgc atagtttatt ccgtatttta
     2941 aaagcatttg acctaaacca tagcctctat aattatcatc gattgcaact gtcgtaattt
     3001 gagcttgatc gataacaatc cataaaccta aataaccaat aatttgttgt tcaaattcta
     3061 agacaaaata tttcgcaaag ttattttgtt ctatttcatg ataaaatgcg tcaattgtcc
     3121 aagaactatc attgaaactc cgacgctcaa tatcaaagac ttgtggcaca tcttctttgg
     3181 tcatctctct aatgtttaat tgttcttttg actgttgatc caatttcgtt ccgcctcagc
     3241 taatttatgg tatttaggag taaatgtatg tacgtctgaa ggtttatcta tcaattgatg
     3301 catgactgat gcatttggta gctgcgcaat cacatcacct tgtaattcat cttgtaattt
     3361 tacagtatct ttcccaatat aaataaatgg ttggtttaaa tcttctaaaa aagctcgcaa
     3421 tgcctctatc gacatatatt gatcttctaa aatagtcact aattgaccat tttgccactg
     3481 gaatatgcct gtataaactg cttgtcgtct tgcatcaaac acaggaacca ataatttatc
     3541 agtatgatcg attgttgctg ccaatgcctt taatgatgaa acaccatata atttaacatc
     3601 taacgcatac gctaatgttt tagcaacagt aacaccgata cgtaagccag tatatgaacc
     3661 aggaccttca gcaacaataa tcgcatctaa ttgctgttta gctattttgc tctgctcaaa
     3721 tagctgacta atcgcaggca ttaattgcac tgaatgattt tgtttagaat ccgtagttat
     3781 ttcagctaaa acttcatcgt tttgcatcaa tgctactgat aatggttgat tcgatgtatc
     3841 aatgagcagc gaattcatgg ataattgcct ccttaatttg ttcataatgt tctccttgcg
     3901 cgaacaactc aatttgtctt gtattttcag atattgttga aatattaata gataaatgcg
     3961 tcgatggaag taaatctttt ataaattgac tccattcaat aacagtaatt gcctgatctt
     4021 cgaaaaattc atcaaaccct aaatcttcat cagaatcttc taagcgataa caatccatat
     4081 gatgcaattt taaattttta cccctatatg atttaatgat gttaaatgtc ggggaattaa
     4141 tcgttcgtct tacaccaaga gcttttccta taaattgcgt taacgttgtt ttacctgctc
     4201 ctaaatctcc gttaagtaaa atcaaatcac cacttttcaa ttgctcaact aaaaacatag
     4261 caaattgatt catttcatct aaattattta tctttatcaa tgttgattct cctatattgt
     4321 gcttttcatt cataaaaatg attatccatt gttcaatcgt atctaacttt atatttaacc
     4381 tttatattgt aacaaatttc aacttaaatt tcttatcttt gaaacagatt atctcttcaa
     4441 agttaattgt aagaaaattt aaaatattta ttgacatact aaagcagata tagtaaatta
     4501 aatttatcaa atttttagac aattctaact attaaagtga tatataccat tcacggaagg
     4561 agtataataa aatgcttaat caatatactg aacatcaacc gacaacttca aatattatta
     4621 ttttattata ctctttagga ctcgaacgtt agtaaatatt tactaaacgc tttaagtcct
     4681 atttctgttt gaatgggact tgtaaacgtc ccaataatat tgggacgttt ttttatgttt
     4741 tatctttcaa ttacttattt ttattactat aaaacatgat taatcattaa aatttacggg
     4801 ggaatttact atgcgaagcg acatgatcaa aaaaggagat caccaagcac cagcaagaag
     4861 tcttttacat gccacgggcg cgctaaaaag tccaactgat atgaacaaac catttgtagc
     4921 tatttgtaac tcttatattg atattgttcc tggacatgtt catttaagag agcttgcaga
     4981 tatagctaaa gaagcaatta gagaagccgg tgccattcca tttgaattca atacaattgg
     5041 tgttgatgat ggaatagcta tgggacatat cggaatgcga tattctctac catcacgtga
     5101 aattattgca gatgcagctg aaactgtaat taacgctcat tggtttgacg gcgtatttta
     5161 cattcctaat tgtgacaaga ttacacccgg tatgatttta gcagccatga ggacaaacgt
     5221 accagctatc ttttgctctg gtggaccaat gaaagctggc ttatctgcac atggaaaagc
     5281 attaacactt tcatcaatgt ttgaagcagt cggcgcattt aaagaaggat cgatttctaa
     5341 agaagaattt ttagatatgg aacaaaatgc ctgccctact tgtggttcat gtgctgggat
     5401 gtttactgca aattcaatga actgtttgat ggaagtttta ggtctagcat taccatacaa
     5461 cggtactgca cttgcagtca gtgatcaacg acgcgaaatg attcgccaag cagcttttaa
     5521 attagttgaa aatattaaaa atgatttaaa accacgtgat atcgttactc gcgaagcaat
     5581 tgatgatgca tttgcacttg atatggctat gggtggttca acaaacacag tactgcatac
     5641 gttagccatt gccaatgaag ctggtattga ttatgactta gagcgcatta atgctattgc
     5701 caaacgcacg ccatatttat caaaaatagc acctagttca tcgtattcaa tgcatgatgt
     5761 gcatgaagct ggtggcgtcc cagcaattat taatgaattg atgaagaaag atggcacgtt
     5821 acacccagat agaatcacag ttactggcaa aacgttacgt gaaaataacg aaggcaaaga
     5881 aattaagaac tttgatgtca ttcaccctct tgatgcacca tatgatgcac aaggcggttt
     5941 atctatctta tttggtaata tcgcccctaa aggcgcagtt attaaagttg gcggcgttga
     6001 tccatctatc aaaacattta ctgggaaagc aatttgtttc aattcgcatg atgaagctgt
     6061 tgaagcaata gacaatcgta ccgttcgtgc aggccacgtc gttgtcatta gatatgaagg
     6121 acctaaaggt ggaccaggta tgcctgaaat gttagcacct acttcctcta ttgttggtcg
     6181 cggcttaggt aaagatgttg cattaattac tgatgggcgt ttttccggtg ccacaagagg
     6241 tattgcagtt ggtcatattt cccctgaagc tgcatctggt ggaccaattg ccttaattga
     6301 agatggagat gagattacta ttgatttaac aaatcgtaca ttaaacgtaa accagcctga
     6361 agatgttcta gcgcgtcgcc gagaatcttt aacaccattt aaagcgaaag taaaaacagg
     6421 ttatctagct cgttatactg ccctagtaac tagcgcaaat acaggtggcg tcatgcaagt
     6481 ccctgagaat ttaatttaat ttatttttat attggagatg gttaaaatgt ctaaaactca
     6541 acatgaagta aaccaaaata ttgacccttt aaaaatggct gaatcacttg aacccgaaca
     6601 actaaatgaa aaaactttaa atgatatgcg ttcaggatca gaagtgctag tagaagctct
     6661 acttaaagaa aatgtggatt atttattcgg ttatcctggt ggtgccgtac tacctttata
     6721 tgacacgttt tatgatggta aaatcaaaca tattttagca agacacgaac aaggtgctgt
     6781 tcatgctgca gaaggttatg cacgtgtatc tggtaaaact ggcgtcgttg tagttacaag
     6841 cggtccaggt gcaacaaatg taatgacagg tattacggat gcacattgcg actctttacc
     6901 tctagttgta ttcaccggac aagttgctac accaggcatt ggtaaagatg cattccaaga
     6961 agcggatatt ctatctatga cttcaccaat tacaaaacaa aattatcaag tgaaacgtgt
     7021 tgaagatatc cctaaaatcg tacacgaagc tttccatgta gcgaattctg gacgcaaagg
     7081 tcctgtagtg attgattttc caaaagatat gggtgtttta gctacaaatg tggatttatg
     7141 cgacgaaatc aatattccag gttatgaagt tgttacagaa ccagaaaata aagacattga
     7201 cactttcatc tcacttttaa aagaagcgaa aaagcctgtc gtattagccg gcgcaggtat
     7261 taatcaatca aaatcaaatc aattattaac acagtttgtt aataaacatc aaatcccaac
     7321 agttactact ttactaggtc taggtgctgt accttatgag gatacactat ttttaggtat
     7381 gggaggtatg catggttctt atgctagtaa catggcatta actgagtgtg atttactcat
     7441 taatttaggt agccgcttcg atgatagatt agcaagcaaa cctgatgcct ttgcacctaa
     7501 cgccaaaatt gtacatgtag atattgatcc ttcagaaatc aataaagtta ttcatgcaga
     7561 tttaggtatt attgcagact gtaaaagatt tttagaatgt ttaaatgata aaaatgttga
     7621 gactatagca cacagtgact gggttaaaca ttgtcaaaat aataagcaga aacacccatt
     7681 taaacttggt gaaaaagatc cagtattttg taagccacaa caaacaatcg aatatatcgg
     7741 caaaattaca aatggtgaag caattgttac tacagacgtg ggacaacatc aaatgtgggc
     7801 agctcaattt tatccattta aaaatcacgg acaatgggtt acaagtggtg gtttaggaac
     7861 aatgggattc ggtattcctt cgtcaattgg tgccaaatta gctaatcctg ataaaacagt
     7921 cgtatgtttc gtcggtgacg gtggtttcca aatgacaaac caagaaatgg cactattacc
     7981 cgaatatggt ttagatgtca aaatcgtact aatcaataat ggaacactag gtatggttaa
     8041 acaatggcaa gataagttct ttaatcaacg cttctcacac tcagtattta atggtcaacc
     8101 tgattttatg aaaatggcag aagcatatgg cgtcaaaggt ttcttaatcg ataagccaga
     8161 acaactggaa gaacaattag atgcagcgtt tgcttatcaa ggaccagctt taattgaggt
     8221 tcgtatttcc cctactgaag ctgtaaaccc aatggttccg agtggcaaat caaatcatga
     8281 aatggagggc ttataatgac aagaattctt aaattacaag ttgcggatca agtcagcacg
     8341 ctaaatcgaa ttacaagtgc ttttgttcgc ctacaatata atatcgatac attacatgtt
     8401 acacattctg aacaacctgg gatttctaac atggaaattc aagtcgatat tcaagatgat
     8461 acatcacttc atatattaat taaaaaatta aaacaacaaa ttaatgtttt aacggttgaa
     8521 tgctacgacc ttgttgataa cgaagcttaa ttttaagaca aaggcaatga tgcgctaatt
     8581 agttatagat atatcatagg ctgctagtta acatctgcca ctattacaaa gttatatttc
     8641 agaattttca aaaaaacaaa atatttaatt atttggagga atttattatg acaacagttt
     8701 attatgatca agatgtaaaa acggacgctt tacaaggcaa aaaaattgca gtagtaggtt
     8761 atggatcaca aggccacgcg catgcacaaa acttaaaaga caatggatat gatgtagtca
     8821 tcggtattcg cccaggtcgt tcttttgaca aagctaaaga agatggattt gatgtgttcc
     8881 ctgttgcaga agcagttaag caagctgatg taattatggt gctattacct gatgaaattc
     8941 aaggtgatgt atacaaaaac gaaattgaac caaatttaga aaaacataat gcgcttgcat
     9001 ttgctcatgg ctttaacatt cattttagtg ttattcaacc accagctgat gttgatgtat
     9061 ttttagtagc tcctaaagga ccgggtcatt tagttagacg tacatttgtt gaaggttctg
     9121 ctgtaccatc actatttggt attcaacaag acgcttcagg tcaagcacgt aatattgctt
     9181 taagttatgc aaaaggtatt ggtgcaactc gtgcaggtgt tattgaaaca acatttaaag
     9241 aagaaactga gacagattta tttggtgaac aagcagtact ttgcggtggt gtatcgaaat
     9301 taattcaaag tggctttgaa acattagtag aagcgggtta tcaaccagaa ttagcttatt
     9361 ttgaagtatt acatgaaatg aaattaatcg ttgatttgat gtatgaaggc ggtatggaaa
     9421 atgtacgtta ctcaatttca aatactgctg aatttggtga ctatgtttca ggaccacgtg
     9481 ttatcacacc agatgttaaa gaaaatatga aagctgtatt aactgatatc caaaatggta
     9541 acttcagtaa tcgctttatc gaagacaata aaaatggatt caaagaattt tataaattac
     9601 gcgaagaaca acatggtcat caaattgaaa aagttggtcg tgaattacgc gaaatgatgc
     9661 cttttattaa atctaaaagc attgaaaaat aagatagacc tacaatgagg agttgttaaa
     9721 tatgagtagt catattcaaa tttttgatac gacactaaga gacggtgaac aaacaccagg
     9781 agtgaatttt acttttgatg aacgcttgcg tattgcattg caattagaaa aatggggtgt
     9841 agatgttatt gaagctggat ttcctgcttc aagtacaggt agctttaaat ctgttcaagc
     9901 aattgcacaa acattaacaa caacggctgt atgtggttta gctagatgta aaaaatctga
     9961 catcgatgct gtatatgaag caacaaaaga tgcagcgaag ccggtcgtgc atgtttttat
    10021 agcaacatca cctattcatc ttgaacataa acttaaaatg tctcaagaag acgttttagc
    10081 atctattaaa gaacatgtca catacgcgaa acaattattt gacgttgttc aattttcacc
    10141 tgaagatgca acgcgtactg aattaccatt cttagtgaaa tgtgtacaaa ctgccgttga
    10201 cgctggagct acagttatta atattcctga tacagtcggc tacagttacc atgatgaata
    10261 tgcacatatt ttcaaaacct taacagaatc tgtaacatct tcaaatgaaa ttatttatag
    10321 tgctcattgc catgacgatt taggaatggc tgtttcaaat agtttagctg caattgaagg
    10381 cggtgcaaga cgaattgaag gcactgtaaa tggtattggt gaacgagcag gtaatgcagc
    10441 acttgaagaa gtcgcgcttg cactatacgt tcgaaatgat tattatggtg ctcaaactgc
    10501 ccttaatctc gaagaaacta aaaaaacatc ggatttaatt tcaagatatg caggtattcg
    10561 agtgcctaga aataaagcaa ttgttggcca aaatgcattt agtcatgaat caggtattca
    10621 ccaagatggc gtattaaaac atcgtgaaac atatgaaatt atgacacctc aacttgttgg
    10681 tgtaagcacg actgaacttc cattaggaaa attatctggt aaacacgcct tctcagagaa
    10741 gttaaaagca ttaggttatg acattgataa agaagcgcaa atagatttat ttaaacaatt
    10801 caaggccatt gcggacaaaa agaaatctgt ttcagataga gatattcatg cgattattca
    10861 aggttctgag catgagcatc aagcacttta taaattggaa acactgcaac tacaatatgt
    10921 ctctagcggc cttcaaagtg ctgttgttgt tgttaaagat aaagaggatc atatttacca
    10981 ggattcaagt attggtactg gttcaatcgt agcaatttac aatgcagttg atcgtatttt
    11041 ccaaaaagag acagaattaa ttgattatcg tattaattct gtcactgaag gtactgatgc
    11101 ccaagcagaa gtacatgtaa atttattgat tgaaggtaag actgtcaatg gctttggtat
    11161 tgatcatgat attttacaag cctcttgtaa agcatacgta gaagcacatg ctaaatttgc
    11221 agctgaaaat gttgaaaagg taggtaatta attatgactt ataacattgt tgccctacct
    11281 ggtgatggaa tcggtccaga aattttgaac ggatctctat ccttgcttga aattataagt
    11341 aataaatata actttaatta tcaaatagag caccacgaat ttggtggtgc ctctattgat
    11401 acattcggcg agcctttaac tgagaaaacc ttaaatgcgt gtaaaagagc agatgctatt
    11461 ttactgggtg caatcggtgg acctaaatgg acagatccta acaatcgacc agaacaagga
    11521 ttattaaaat tacgtaaatc attaaattta tttgcaaata tacgccccac tatcgttgtc
    11581 aaaggcgcta gttctttatc acctttaaag gaagatcgcg ttgaaggcac agatttagtt
    11641 atagtccgtg aattgacaag tggtatttat tttggagaac ctagacattt taataatcac
    11701 gaggccttag attctcttac ttatacaaga gaagaaatag aacgcattgt tcacgtagca
    11761 tttaaattgg ctgcttcaag acgaggaaaa ctaacatcag ttgataaaga aaatgtatta
    11821 gcttctagta aattgtggcg caaagtcgta aatgaagtga gtcaattata tccagaagta
    11881 acagtaaatc acttacttgt tgatgcttgt agcatgcatt taatcacaaa tccaaaacaa
    11941 tttgacgtca tagtttgtga aaacttattt ggcgatattt taagtgatga agcttcagtg
    12001 attcctggtt cacttggttt atcaccttct gctagtttta gtaacgatgg tccaagatta
    12061 tatgagccta ttcatggatc agcaccagat attgcaggta aaaacgttgc caatccattt
    12121 ggaatgattc tatctttagc gatgtgttta cgtgaaagct taaatcaacc agatgctgca
    12181 gatgaattag aacaacatat ttacaacatg attgaacatg ggcaaacgac agcagattta
    12241 ggcggcaaac tgaatactac tgatattttc gaaattctat ctcaaaaatt gaatcactaa
    12301 gggggagatg taaatgggtc aaacattatt tgacaaggtg tggaacagac atgtgttata
    12361 cgggaaattg ggcgaaccgc aactattata cattgattta caccttatac atgaagttac
    12421 ttctcctcaa gcatttgaag gacttaggct tcaaaacaga aaattaagac gcccagattt
    12481 aacatttgca acactcgatc acaatgttcc tactattgat attttcaata ttaaagatga
    12541 aattgcaaac aaacaaatca caacattaca aaaaaacgcc atagattttg gggtgcatat
    12601 ttttgatatg ggctctgatg aacaaggtat tgttcacatg gtaggacctg agacaggact
    12661 tacacagccc ggcaaaacaa tcgtttgtgg tgactctcac acagcaacac atggagcatt
    12721 tggtgctatt gcatttggaa ttggaacaag tgaagttgaa catgttttcg caactcaaac
    12781 gctatggcaa acaaaaccca aaaacttaaa aatcgatatt aatggtacct taccaacagg
    12841 cgtctatgct aaggacatta ttctgcattt aattaaaacg tatggtgttg actttggtac
    12901 aggctatgct ttggaattta ctggcgaaac aattaaaaac ctttcaatgg acggtcgaat
    12961 gactatttgt aacatggcta tcgaaggtgg tgccaaatac ggcataatcc aacctgatga
    13021 tataacattt gaatatgtta aagggagacc atttgccgat aacttcgcta aatcagttga
    13081 taagtggcgt gagctatatt ctgatgacga cgcgatattt gatcgtgtaa ttgaacttga
    13141 tgtttcaaca ttagaaccac aagtgacatg gggaactaat cctgaaatgg gtgttaattt
    13201 cagtgaacca ttccctgaaa tcaatgatat caacgatcaa cgtgcgtatg attatatggg
    13261 gttagaacca ggtcaaaaag ctgaagatat cgacttaggg tatgttttcc tcggttcatg
    13321 tacaaatgct agactatcag atttgattga agctagtcat attgttaaag gaaataaagt
    13381 tcacccaaat attacagcta ttgtcgtacc aggttctcgt acagtaaaaa aagaagctga
    13441 aaaattaggt ctagatacta tctttaaaaa tgcaggattt gaatggcgtg aaccaggatg
    13501 ttcaatgtgt ttaggcatga atcctgacca agtacctgag ggtgtacatt gtgcatctac
    13561 aagtaatcga aacttcgaag gacgacaagg caaaggtgct agaacacatt tagtatcccc
    13621 tgctatggca gcagcagcag ctattcatgg taaatttgtg gacgtaagaa aggtggttgt
    13681 ttaaatggca gcaatcaaac ctattacaac atataaaggt aaaatagtcc ctcttttcaa
    13741 cgataatatc gatacagatc aaatcattcc taaagtacac ttaaagcgta tttcaaaaag
    13801 tggctttggt ccatttgctt ttgatgaatg gcggtactta cctgatggtt cagataatcc
    13861 tgatttcaat ccaaataagc ctcaatataa aggtgcatcc atattaatta ctggagataa
    13921 ttttggatgt ggttcaagtc gtgaacatgc agcttgggca cttaaggact atggctttca
    13981 tattattatt gcaggaagtt tcagtgacat tttttatatg aattgtacaa aaaatgcaat
    14041 gttaccaatt gttttagaaa aaaatgcacg tgaacatctt gctaaatatg ttgaaattga
    14101 ggtcgattta ccaaatcaaa ctgtgtcatc accagacaag agtttccatt ttgaaattga
    14161 tgaaacttgg aagaataaac ttgtaaatgg cttagatgac attgcaatca ccctacaata
    14221 tgaatcatta atagaaaaat atgaaaaatc actttaaggg agttgaatat tatgacagtc
    14281 aaaacaacag tttctacgaa ggatatcgat gaagcatttt taagacttaa agatattgtc
    14341 aaagaaacac ctttacaatt agaccattac ttatctcaaa agtatgattg taaagtttat
    14401 ttaaaacgag aagatttaca atgggtacgt tcttttaaat taagaggtgc ttacaacgct
    14461 atttctgttt tatcagatga agctaaaagt aaaggaatta catgtgcgag tgcaggtaat
    14521 catgctcaag gtgttgccta tacagctaaa aaacttaatt taaacgctgt tatctttatg
    14581 ccagtcacta cacctttaca aaaggtaaat caagtaaagt tctttggaaa tagtaacgtt
    14641 gaagttgtac tcactggtga tacatttgat cactgtttag ctgaagcttt aacttataca
    14701 agtgaacatc aaatgaactt tatagatcca ttcaataatg ttcatacaat ttctggacaa
    14761 ggtacgcttg ctaaagaaat gctagaacaa gcaaagtctg acaatgttaa ctttgattat
    14821 ctatttgccg caattggtgg tggtggttta atttcaggta ttagtaccta ttttaaatcc
    14881 tattctccca acacaaaaat tatcggagtt gaaccttcag gtgctagtag tatgtatgaa
    14941 tctgttgtcg taaataatca ggttatcaca ttacctaata tcgataaatt tgtcgatgga
    15001 gcttctgtag ccagagttgg cgatattact tttgaaattg ccaaaaaaaa tgtagataac
    15061 tacgtacaag tggatgaagg tgctgtatgt tcaacaattt tggatatgta ttcaaaacaa
    15121 gcaatagtag cagaacccgc tggcgcttta agtgtaagtg cgcttgaaaa ctataaagat
    15181 catattaaag gtaaaacagt ggtttgtgtc attagtggtg gtaataatga tattaatcga
    15241 atgaaagaaa ttgaagaacg ttcattacta tacgaagaaa tgaagcatta ctttatctta
    15301 aatttccctc aacgtccagg tgcattgaga gaatttgtaa atgacgtatt aggacctcaa
    15361 gacgatatta ctaaatttga atacttaaaa aaatcttctc aaaatacagg tactgtcatt
    15421 attggtattc aacttaaaga tgatgatgat ttaatacaac tcaaacaacg tgtaaatcat
    15481 ttcgatcctt ccaatattta tattaatgaa aataagatgt tatattcatt gttaatttag
    15541 cacatagtaa gaaaagcagt cataaattga tttctgattg aaatcatctt atgactgctt
    15601 tttattatac tttacatttc tcgttcgtcg ctaagaacct ttcttgactg gaaatgataa
    15661 tttaataatg tacacttttg attgtttaaa catgtacaa
//
LOCUS       DAPSKH010000063        15430 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPSKH010000063 DAPSKH010000000
VERSION     DAPSKH010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 15430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15430
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.063"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..1053)
                     /locus_tag="RPH49_002201"
     CDS             complement(<1..1053)
                     /locus_tag="RPH49_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDY5125326.1"
                     /translation="MKIADLMTLLDHHVPFSTAESWDNVGLLIGDEDVEVTGVLTALD
                     CTLEVVNEAIEKGYNTIISHHPLIFKGVTSLKANGYGLIIRKLIQHDINLIAMHTNLD
                     VNPYGVNMMLAKAMGLKNISIINNQQDVYYKVQTYIPKDNVGPFKDKLSENGLAQEGN
                     YEYCFFESEGRGQFKPVGEANPTIGQIDKIEYVDEVKIEFMIDAYQKSRAEQLIKQYH
                     PYETPVFDFIEIKQTSLYGLGVMAEVDNQMTLEDFAADIKSKLNIPSVRFVGKSNQKI
                     KRIAIIGGSGIGYEYQAVQQGADVFVTGDIKHHDALDAKIHGVNLIDINHYSEYVMKE
                     GLKTLLMNWFNTEKINI"
     gene            complement(1056..1733)
                     /locus_tag="RPH49_002202"
     CDS             complement(1056..1733)
                     /locus_tag="RPH49_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDY5125327.1"
                     /translation="MISLNNRLTTVSRFLKQGTIADIGSDHAYLPIYAIQNHLCECGI
                     AGEVIQGPFQAAVKNVAANQLEDRIDVRLGDGLSVIHPEDVIDNITICGMGGPLIAKI
                     LKDGQDKLSQHPRLILQSNIQTENLRQTLQQLNYEIIDEIIMEEKGHIYEIVVAEYST
                     QLIELSSDELKFGPKLLNNKNEYFIKKWQRELEALYHIKSKLNTEQHHQRLAQINDEI
                     AVIERVL"
     gene            complement(1864..2970)
                     /gene="rpoD"
                     /locus_tag="RPH49_002203"
     CDS             complement(1864..2970)
                     /gene="rpoD"
                     /locus_tag="RPH49_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDY5125328.1"
                     /translation="MSDNTVKIKKQTIDPTLTLEDVKKQLIEKGKKEGHLSHEEIAEK
                     LQNFDIDSDQMDDFFDQLNDNDISLVNEKDSSDTDEKLNPSDLSAPPGVKINDPVRMY
                     LKEIGRVNLLSAQEEIELAKRIEQGDEVAKSRLAEANLRLVVSIAKRYVGRGMLFLDL
                     IQEGNMGLIKAVEKFDFNKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LIRVQRQLLQDLGRDPAPEEIGEEMDLPAEKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDQEAQSPSDHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVGK
                     VFGVTRERIRQIEAKALRKLRHPSRSKRLKDFMD"
     gene            complement(3194..5011)
                     /locus_tag="RPH49_002204"
     CDS             complement(3194..5011)
                     /locus_tag="RPH49_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDY5125329.1"
                     /translation="MRIDQSIINEIKDKTDILDLVSEYVKLEKRGRNYIGLCPFHDEK
                     TPSFTVSEDKQICHCFGCKKGGNVFQFTQEIKDISFVEAVKELGDRVNVAVDIEATQS
                     NSNVQIASDDLQMIEMHELIQEFYYYALTKTVEGEQALTYLQERGFTDALIKERGIGF
                     APDSSHFCHDFLQKKGYDIELAYEAGLLSRNEENFSYYDRFRNRIMFPLKNAQGRIVG
                     YSGRTYTGQEPKYLNSPETPIFQKRKLLYNLDKARKSIRKLDEIVLLEGFMDVIKSDT
                     AGLKNVVATMGTQLSDEHITFIRKLTSNITLMFDGDFAGSEATLKTGQHLLQQGLNVF
                     VIQLPSGMDPDEYIGKYGNDAFTTFVKNDKKSFAHYKVSILKDEIAHNDLSYERYLKE
                     LSHDISLMKSSILQQKAINDVAPFFNVSPEQLANEIQFNQAPANYYPEDEYGGYDEYG
                     GYIEPEPIGMAQFDNLSRQEKAERAFLKHLMRDKDTFLNYYESVDKDNFTNQHFKYVF
                     EVLHDFYSENDQYNISDAVQYVNSNELRETLISLEQYNLNDEPYENEIDDYVNVINEK
                     GQETIESLNHKLREATRIGDVELQKYYLQQIVAKNKERM"
     gene            complement(5072..5890)
                     /locus_tag="RPH49_002205"
     CDS             complement(5072..5890)
                     /locus_tag="RPH49_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDY5125330.1"
                     /translation="MEKIKIIVASDSIGETAELVARAGISQFNPKQCKNELLRYPYIE
                     SFEDVDEVIQVAKDTNAIIVYTLIKPEMKQYMSEKVAEFQLKSVDIMGPLMDLLSASV
                     EEKPYNEPGIVHRLDDAYFKKIDAIEFAVKYDDGKDPKGLPKADIVLLGISRTSKTPL
                     SQYLAHKSYKVMNVPIVPEVTPPDGLYDIDPKKCIALKISEEKLNRIRKERLKQLGLG
                     DTARYATEARIQEELNYFEEIVSEIGCPVIDVSQKAIEETANDIIHYIEQNKSK"
     gene            complement(5901..6524)
                     /locus_tag="RPH49_002206"
     CDS             complement(5901..6524)
                     /locus_tag="RPH49_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001797828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125331.1"
                     /translation="MELSQRQERIIEIVKTKGPITGEQIADKLNLTRATLRPDLAILT
                     MSGFLEARPRVGYYYSGKSKGKFFNEKLRQFEVKDYMSQPVVLRENTTVYDAICTIFL
                     EDVSTLFIINEDNDFVGVCSRKDLLRASMIGADIHTVPISVNMTRMPNVTYLEESELV
                     IYAADRMIEKEIDSIPIVRKKDNQKYEVIGRISKTTIAKLLVALYKE"
     gene            6859..8250
                     /locus_tag="RPH49_002207"
     CDS             6859..8250
                     /locus_tag="RPH49_002207"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase"
                     /protein_id="HDY5125332.1"
                     /translation="MAKDMDTIVSLAKHRGFVFPGSDIYGGLSNTWDYGPLGVELKNN
                     VKKAWWQKFITQSPFNVGIDAAILMNPKVWEASGHLNNFNDPMIDNKDSKIRYRADKL
                     IEDYMQDVKGDENFIADGLSFEQMKKIIDDEGIVCPVSKTANWTEIRQFNLMFKTFQG
                     VTEDSTNEIFLRPETAQGIFVNYKNVQRSMRKKLPFGIGQIGKSFRNEITPGNFIFRT
                     REFEQMELEFFCKPGEEIEWQNYWKTFASDWLTSLNMSSENMRLRDHDEDELSHYSNA
                     TTDIEYKFPFGWGELWGIASRTDFDLRKHAEHSGEDFRYHDPETNEKYIPYCIEPSLG
                     ADRVTLAFLCDAYDEEGVEGSKDARTVLHFHPALAPYKAAILPLSKKLSGEAIKIFEQ
                     LSSKFSIDFDESQSIGKRYRRQDEIGTPYCVTFDFDSLEDNQVTVRDRDSMEQVRMPI
                     SELEAFLTEKTKF"
     gene            complement(8401..9147)
                     /gene="recO"
                     /locus_tag="RPH49_002208"
     CDS             complement(8401..9147)
                     /gene="recO"
                     /locus_tag="RPH49_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDY5125333.1"
                     /translation="MRQKGIIIKAVDYGESDKIITILNEHGAKVPLMARRAKKVKTGL
                     QAQTQLFVYGLFIYNQWRGMGTLNSVDVISQHYKLQMDLYVSSYASLAAETIERSMDE
                     GDIAPYNYQLLQFVLEKIESGTSAQLMSVVVMLKCMKRFGFTASFNRCAVSGNDTQAD
                     LIGYSFKFDGAISRQEASKDVHAVILSNKTLYLLDVLQKLPIDKMNSLNIHQEIIDEM
                     SDIILMLYREYAGMFFKSQKLINQLKRLEQ"
     gene            complement(9175..10074)
                     /gene="era"
                     /locus_tag="RPH49_002209"
     CDS             complement(9175..10074)
                     /gene="era"
                     /locus_tag="RPH49_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDY5125334.1"
                     /translation="MTEHKSGFVSIIGRPNVGKSTFVNRVIGHKIAIMSDKAQTTRNK
                     IQGVMTRDDAQIIFIDTPGIHKPKHKLGDYMMKVAKNTLSEIDAIMFMVNANEEIGRG
                     DEYIIEMLKNVKTPVFLVLNKIDLVHPDELMPKIEEYQSYMDFTEIVPISALEGLNVD
                     HFIDVLKTYLPEGPKYYPDDQISDHPEQFVVGEIIREKILHLTSEEIPHAIGVNVDRM
                     VKESEDRVHIEATIYVERDSQKGIVIGKGGKKLKEVGKRARRDIEMLLGSKVYLELWV
                     KVQRDWRNKVNFIRQIGYVEDQD"
     gene            complement(10075..10479)
                     /gene="cdd"
                     /locus_tag="RPH49_002210"
     CDS             complement(10075..10479)
                     /gene="cdd"
                     /locus_tag="RPH49_002210"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDY5125335.1"
                     /translation="MSYQPHYFQEVRKAQQESYSPYSQFKVGAYLKTKDGRTFYGTNV
                     ENASYPLSICAERASLVSAISQGYRPGDFESITVTVDADKPSSPCGACRQVLKELCDD
                     DMPVYMTNHKGDMVMMTVAELLPFGFSGKDLE"
     gene            complement(10490..10834)
                     /locus_tag="RPH49_002211"
     CDS             complement(10490..10834)
                     /locus_tag="RPH49_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDY5125336.1"
                     /translation="MKRFKYALDGLKILIQKDYKFLLHVFAMIVAIVFGLVLNINRIE
                     WIFILIAIALVLTVEALNTAIEYVVDLVTVEYHDLAKYAKDIAAFSVLIVSILAFIIG
                     LIVFLPHFIALF"
     gene            complement(10837..11304)
                     /gene="ybeY"
                     /locus_tag="RPH49_002212"
     CDS             complement(10837..11304)
                     /gene="ybeY"
                     /locus_tag="RPH49_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDY5125337.1"
                     /translation="MFTIDFSDHTGLVKDAWYKQIEDLLEFAKKEEHIEDDAELSVTF
                     VDKQEIQEINRTYRDKDKVTDVISFALEEDEPEIDFSDLDIPRVLGDIIICTDVAQEQ
                     ANNYGHSFERELGFLALHGFLHLLGYDHMTEADEKEMFGRQDTILNAYGLTRD"
     gene            complement(11305..12252)
                     /locus_tag="RPH49_002213"
     CDS             complement(11305..12252)
                     /locus_tag="RPH49_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDY5125338.1"
                     /translation="MPGIIQIDDMNQSQALIGNNDEHLKAIEESFDVVIHARGQEVAV
                     KGTKIENVEKAESVLINLLKVIDLGNNITIKDVEAAIKMAHNNTIQHLLDLYDEEITK
                     DAFGKTIRAKTMGQRIYVNAMKNNDLVFGIGPAGTGKTFLAVVYAAKQLRKGAVKRIV
                     LTRPAVEAGESLGFLPGDLKEKVDPYLRPLYDGLYTVLGREQTERFIERGIIEIAPLA
                     YMRGRTLEDAFVILDEAQNTTHAQMKMFLTRLGFGSKMVVTGDQTQIDLPKGVKSGLK
                     EAVSRLHNVKGISILKLDQSDVVRHPLVSKIIEHYEGEN"
     gene            complement(12556..13254)
                     /locus_tag="RPH49_002214"
     CDS             complement(12556..13254)
                     /locus_tag="RPH49_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron transporter"
                     /protein_id="HDY5125339.1"
                     /translation="MSVGILIFVISVIISIITTMRENSHKDRQNQKPPQKTSTDNEPK
                     KGGFFEEIERTFKEISEELNEEEKKSSKRKYDDTLPPLFDELPKEEPKSKPVVEPMAP
                     KKQPETKPMTEKPITVPKAEPVEQKHRPSRQDNSDEIRRQLEKSLRDDIKTIRTDIDR
                     EKEKQIAKMEKRARDIIEDKYLSERTKRLKLKQLLNSQNVEKDLTKSAFQFDKDEVIN
                     GMIWSEILAKPKQL"
     gene            complement(13271..14260)
                     /gene="floA"
                     /locus_tag="RPH49_002215"
     CDS             complement(13271..14260)
                     /gene="floA"
                     /locus_tag="RPH49_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500186.1"
                     /note="flotillin-like protein involved in membrane lipid
                     rafts; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin-like protein FloA"
                     /protein_id="HDY5125340.1"
                     /translation="MFSLSFIVIAVIIVVALLILFSFVPIGLWISALAAGVHVGIGTL
                     VGMRLRRVSPRKVIAPLIKAHKAGLALTTNQLESHYLAGGNVDRVVDANIAAQRADID
                     LPFERAAAIDLAGRDVLEAVQMSVNPKVIETPFIAGVAMNGIEVKAKARITVRANIAR
                     LVGGAGEETIIARVGEGIVSTIGSSKHHTEVLENPDNISKTVLSKGLDSGTAFEILSI
                     DIADVDISKNIGADLQTEQALADKNIAQAKAEERRAMAVATEQEMKARVQEMHAKVVE
                     AESEVPLAMAEALRSGNISVKDYYNLKNIEADTGMRNAINKRTDQSDDESPEH"
     gene            complement(14278..14961)
                     /locus_tag="RPH49_002216"
     CDS             complement(14278..14961)
                     /locus_tag="RPH49_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDY5125341.1"
                     /translation="MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYS
                     KKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGM
                     ILITISITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSE
                     SGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEG
                     TRVVVREVD"
     gene            complement(15205..15381)
                     /locus_tag="RPH49_002217"
     CDS             complement(15205..15381)
                     /locus_tag="RPH49_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016998564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDY5125342.1"
                     /translation="MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVK
                     RKKKSEAARKRKFK"
BASE COUNT         4780 a         2885 c         2123 g         5642 t
ORIGIN      
        1 tatatttatt ttttctgtat tgaaccaatt cattagtaac gtttttaaac cttctttcat
       61 cacatattcg ctgtaatgat taatatcaat taagttcaca ccatgaattt tagcatctaa
      121 ggcatcatga tgtttaatat cacctgtaac aaagacatct gcgccttgtt ggacagcttg
      181 atattcatat ccaatacctg aaccaccaat aattgcaata cgtttaattt tctgattaga
      241 cttaccaaca aaacggacac ttgggatatt taatttagat ttaatatcag ctgcgaaatc
      301 ttccaatgtc atttgattat ccacttctgc cataacgcca agtccataaa gggatgtttg
      361 ttttatctca ataaaatcaa ataccggtgt ttcatatgga tggtattgtt taattaattg
      421 ctcagccctt gacttttgat atgcatctat cataaattca attttaactt catctacata
      481 ttcaatttta tcaatttgtc ctattgttgg attagcttca ccaactggtt tgaattgccc
      541 tcttccttca ctttcaaaga aacaatattc ataattacct tcttgtgcta atccattttc
      601 actaagctta tctttaaatg gtccaacatt atccttaggt atatatgttt gaactttata
      661 gtatacatct tgttgattat tgattattga aatgttcttc aaacccatcg ccttcgccaa
      721 catcatattg acaccatacg gatttacatc taaatttgta tgcatcgcta ttaaattaat
      781 gtcatgttga attagttttc taataatcaa accataacca ttagctttta atgatgttac
      841 gcctttaaag attagaggat gatgactaat aatagtatta taaccttttt cgattgcttc
      901 atttactact tccaacgtac agtctaatgc tgttaaaaca ccagtaactt caacatcttc
      961 atcacctatt aacaatccta cattatccca agattcagca gtactaaatg gcacatgatg
     1021 atctaacaat gtcattaaat cagctatttt cattactata acaccctttc aattacagca
     1081 atttcgtcat taatttgagc taaacgttga tgatgttgtt cagtattgag tttcgattta
     1141 atatgataaa gtgcttctaa ctctctttgc cattttttta taaaatattc atttttgttg
     1201 ttcagcaatt ttggtccgaa tttcaattca tcagatgata gctctattaa ttgtgtagaa
     1261 tattctgcta caacaatttc ataaatatgg cctttttctt ccattattat ttcatcaatt
     1321 atttcataat tcaattgttg taatgtttgt cttaaatttt cagtttggat attactttgt
     1381 aaaatcaacc ttggatgttg acttaactta tcttgcccat cttttaaaat tttagcaata
     1441 agtggtccgc ccataccaca aattgtgata ttatcgatta cgtcctcggg atgaataaca
     1501 cttaagccat cccctaaacg tacatcaatt ctatcttcta attgatttgc agctacattt
     1561 ttcactgcag cttgaaaggg gccttgaata acttctcctg caataccgca ttcgcataaa
     1621 tggttttgaa ttgcatagat tggcaaataa gcatgatctg agccaatatc cgcgattgta
     1681 ccttgtttta aaaatcgact taccgtcgtt aatcggttat ttaacgaaat cattttattc
     1741 tcctttatga aaaaagaggt tgaacattat tcaatgtacc aacctcactc aagttaaatc
     1801 ttaatctaaa aataaataag cgcttattca tgtcttggta tcaatcatta aaattgatat
     1861 aaattaatcc ataaagtctt tcaaacgttt actacgactt ggatgtctta attttctaag
     1921 tgcttttgct tcaatttgtc gaatacgttc acgtgtaaca ccgaaaactt taccaacttc
     1981 ttcaagtgtt cttgttctgc cgtcatcaag accaaatctt aatcgtaata cattttcttc
     2041 tctatcagtt aatgtatcaa gcacatcttc taattgctct tttaataatt cataagcagc
     2101 atgatctgaa ggactttgtg cttcctgatc ctcaataaag tctcctaaat gactatcatc
     2161 ttcttcacca attggtgttt ctaatgaaac aggttcttgc gcaattttta aaatttcacg
     2221 aactttttct gctggtaaat ccatttcttc accaatttct tctggtgctg gatctcgacc
     2281 taagtcctgt aataattgac gttgaacacg aattaattta ttaattgttt ctaccatatg
     2341 cacagggata cgaatcgtac gtgcttggtc agcaattgca cgagtgattg cttgtctaat
     2401 ccaccatgtt gcatatgttg aaaacttaaa tcctttgtta aagtcaaatt tttcaacagc
     2461 tttaataaga cccatattac cttcttggat taaatcaagg aataacatac cacgacctac
     2521 gtatctttta gcaatactta caactaaacg taagttcgct tctgcaagtc ttgattttgc
     2581 tacttcatca ccttgttcaa tacgtttggc taattcgatt tcttcttgtg cacttaataa
     2641 gttaacacgc ccaatttctt taaggtacat acgaactggg tcatttattt taacacctgg
     2701 aggggcacta agatcacttg gattcagttt ctcgtcagta tctgaactat ctttttcatt
     2761 aactagtgaa atatcattat catttaattg atcaaagaaa tcatccattt gatcagagtc
     2821 gatatcaaaa ttctgaagtt tttcagcaat ttcttcatga cttaaatgac cctctttttt
     2881 acctttttca attaattgct tcttaacatc ttctaatgtt aatgtcggat caattgtttg
     2941 ttttttaatt ttaactgtgt tatcagacat gaaacggcct cccgatttta aatatgaaca
     3001 ttcgaaattt attcaatatt gctattttaa actaaattct taattaattc atccatattt
     3061 ttaattttat tttacaaatt ggaactaatc ccaatattta tttttcaata gtgttgttta
     3121 aatgcggtaa ctatcattta cccttataca ttttgacata atcattattc gtattattct
     3181 ttaaaatcac atgctacatg cgttctttat tcttagcaac aatttgctgt aaatagtatt
     3241 tttgtaattc tacatcgcca atccttgtag cttcccttaa tttatgattc aatgactcaa
     3301 ttgtttcttg tcctttttca ttaataacat tgacataatc atcaatttca ttttcatatg
     3361 gttcgtcatt caaattatat tgttctaagc taattagtgt ttctctcaac tcatttgaat
     3421 taacatactg tacagcatca ctgatattat attgatcatt ttccgaataa aaatcatgta
     3481 agacttcgaa tacatattta aaatgctgat ttgtgaagtt atccttatca acactttcat
     3541 aataatttaa aaatgtatct ttatctctca ttaaatgttt taaaaatgct cgctccgctt
     3601 tttcttgacg gctcaaattg tcaaattgtg ccataccaat tggctcaggt tcaatgtaac
     3661 ctccatactc atcataaccg ccatactcat cttctggata ataattggct ggtgcttgat
     3721 tgaattgtat ttcgttagct aactgctcag gactaacatt gaaaaatggc gcaacatcat
     3781 ttatagcctt ttgttgcaga attgatgact tcataagtga aatgtcatga ctcagttctt
     3841 tcaaataacg ttcatatgaa aggtcattat gtgcaatttc atcttttaat atacttactt
     3901 tataatgtgc aaatgacttt ttgtcatttt tcacaaaagt agtaaatgcg tcgttgccat
     3961 acttaccaat gtattcatcc ggatccatgc cagatggcaa ttgtataaca aatacattta
     4021 gcccttgctg taacaaatgt tgacctgttt taagtgttgc ttcactaccc gcaaaatccc
     4081 catcaaacat taatgttata tttgatgtta actttcgtat aaaggtgata tgttcatctg
     4141 acaactgtgt acccattgtt gcaacaacgt ttttcaagcc agcagtatca gattttataa
     4201 catccataaa accttctagt aatacaattt catctaattt tctaattgat ttacgtgctt
     4261 tatctaagtt atataacaac tttctttttt gaaagatagg cgtttcagga ctatttaagt
     4321 attttggttc ttgaccggta tatgttcgac ctgaatatcc aacaattctt ccttgcgcat
     4381 ttttcaaagg aaacataatt cgatttcgaa atctatcgta ataactgaaa ttttcttcgt
     4441 tacgtgataa taatccggct tcatatgcta attcaatatc gtaacccttt ttttgaagaa
     4501 aatcatgaca aaaatgtgag ctgtcgggtg caaagccaat gcctcgctct ttaataagcg
     4561 catctgtaaa accacgttct tgtaagtatg ttaatgcttg ttcgccttcg actgtctttg
     4621 ttaaagcgta ataataaaat tcttgtatta actcatgcat ttcaatcatt tgtaaatcat
     4681 cagaagcaat ttgaacattt gagttagatt gtgttgcctc aatatctaca gcaacattaa
     4741 ctctatcacc taattcttta accgcttcaa caaatgatat gtctttaatt tcttgagtaa
     4801 attgaaaaac attgccacct tttttacaac caaaacaatg acaaatttgt ttatcttcag
     4861 aaactgtaaa tgaaggtgtc ttttcatcat gaaaaggaca caaacctata taattgcgtc
     4921 ctctcttttc taattttaca tattcactta ccaagtctaa aatgtcggtt ttatctttta
     4981 tttcattaat gatcgattga tctattcgca aattaaatca cctattaagc attagttata
     5041 ctattatacc taattttcga caaaaatgaa atcatttcga tttattttgt tcaatataat
     5101 ggattatatc gtttgctgtt tcttcgattg ctttttgaga aacatcaatg acaggacatc
     5161 caatttcact tacgatttct tcaaagtaat tcaattcttc ttgaattcgt gcttctgttg
     5221 catatcgagc tgtgtcacct agtcctaatt gttttagtcg ctcttttcta atgcgattta
     5281 atttttcttc acttatttta agtgcgatac atttctttgg atcaatatca tataagccat
     5341 ctggcggtgt cacttctggt acaatcggta cattcataac tttgtaactc ttatgcgcta
     5401 aatactgaga taatggtgtc tttgaagttc tcgaaatacc aagtaaaaca atatcagctt
     5461 taggtaatcc tttaggatct ttaccatcat catatttaac tgcaaactct atcgcatcaa
     5521 ttttcttgaa atatgcatca tctaatctat gaacgatacc tggctcatta taaggttttt
     5581 cttcaaccga agctgataat aaatccatta atggccccat gatatcgaca gacttcaatt
     5641 ggaattctgc tactttctca ctcatatatt gcttcatttc aggtttaata agtgtataaa
     5701 caatgatagc atttgtatct tttgcaactt gaatcacttc atcaacatct tcaaaagatt
     5761 caatatatgg atatcttaat aattcatttt tacattgctt aggattgaat tgtgaaatac
     5821 ctgccctagc aactaactct gccgtttcac ctatagaatc tgaagctacg ataattttaa
     5881 ttttttccat tacttctcac ctattcttta tataatgcta ctaataactt agctattgtt
     5941 gttttggaaa ttcttccaat tacttcatac ttttgattat ctttttttct tacaattgga
     6001 atcgaatcaa tttctttttc aatcattcta tctgctgcgt atatgactaa ttcgctttcc
     6061 tctaaataag tgacattagg catacgtgtc atatttacac tgataggtac tgtatgaata
     6121 tctgctccaa tcattgaagc tcttaataaa tcttttcttg aacacacacc aacaaaatcg
     6181 ttatcttcat taataataaa taatgtactt acatcttcta aaaaaattgt acaaatagcg
     6241 tcataaactg ttgtattctc tcttagcaca acaggttgag acatatagtc cttaacctca
     6301 aattgtcgaa gtttttcatt aaaaaattta ccttttgatt tacctgaata ataatatcca
     6361 actcggggac gcgcttctaa aaaacctgac attgttaata tcgctaaatc tggtctaagc
     6421 gttgctcttg ttaaattcaa cttatctgct atttgttcac cagtaatggg tcctttagtt
     6481 ttaacaattt cgatgattcg ttcttgtctt tgactgagtt ctataggtct tcaccccttt
     6541 tttattcact tattattata ccgatatttc tttcatgtca caaacacatt aattttactt
     6601 gcctttaaat aatctatcaa ttagaataaa cgtacagcga gttaaggata gtgtaagctt
     6661 aacaataaga ttggcgcaac gaatcatttt aaaataaaag cgagtgacta cactaatttg
     6721 ggtggaaccg cgggttaaat acgtaactta ttttgtatta tatacaattt aaaatattaa
     6781 ctcgtcccat ggaagtaaag catatttact atgctgttat tttccatggg gcgttttcat
     6841 gtatgaggag aggtaattat ggcaaaagat atggatacaa ttgtttcatt agcaaaacac
     6901 agaggttttg tgttccctgg tagtgatatt tacggtggtt tatcaaacac atgggattat
     6961 ggtcctttag gtgttgaatt aaagaataat gttaaaaaag cttggtggca aaaattcatt
     7021 acacaatcac cgtttaacgt tggtatcgat gctgcaatct taatgaatcc aaaagtatgg
     7081 gaagcttcag gacacttaaa caacttcaac gacccaatga ttgataataa agatagtaaa
     7141 attcgatatc gcgctgataa attaattgaa gattatatgc aggatgttaa aggtgatgaa
     7201 aacttcattg ccgatggttt aagttttgaa caaatgaaaa aaattattga cgatgaaggt
     7261 attgtttgtc ctgtaagtaa aactgctaac tggactgaaa ttcgccaatt caatttaatg
     7321 tttaaaacat tccaaggtgt aactgaagat tctacaaatg aaattttctt acgtcctgaa
     7381 acagcacaag gtatttttgt aaactataaa aacgtgcaac gttcaatgcg taaaaaatta
     7441 ccatttggta tcggtcaaat tggtaaatca ttccgtaatg aaatcactcc aggtaacttc
     7501 attttcagaa caagagaatt tgaacaaatg gaacttgaat tcttctgtaa acctggagaa
     7561 gaaatcgaat ggcaaaatta ttggaaaact tttgcaagtg actggttaac aagcttaaat
     7621 atgagcagtg aaaatatgcg tttacgtgat catgatgaag atgaattatc tcattactca
     7681 aatgcaacaa ctgatattga atataaattc ccatttggtt ggggtgagtt atggggtatc
     7741 gcaagtcgta cagacttcga cttacgtaaa catgctgaac actctggtga agatttcaga
     7801 taccatgatc cagaaacgaa tgaaaaatat attccatatt gtatcgagcc atcacttggt
     7861 gcagatcgtg taacattagc tttcttatgt gatgcatatg atgaagaagg cgttgaaggt
     7921 agtaaagatg cacgtacagt tttacacttc catcctgcat tagcaccata taaagcagcg
     7981 attttacctt taagtaagaa attatctggc gaagcgatta agatttttga gcaattaagt
     8041 tctaaattct caatcgattt cgatgaatca caatctatcg gtaaaagata ccgtcgtcaa
     8101 gatgaaatcg gtacacctta ttgtgtaaca ttcgactttg attcattaga agataatcaa
     8161 gttacagtac gtgacagaga ttcaatggaa caagttcgta tgccaatctc agagttagaa
     8221 gctttcttaa ctgaaaaaac aaaattctaa ttaaaaagac tctccaccat atgtggtggc
     8281 tatataattt ataaaaagag atactggtta gtaaaattgc cagtatctct tttctattcg
     8341 aaaaaggtat tcaaataaac acatctatgt ggctacttga atacctttta ttattttatg
     8401 ttattgttcc aatcttttta attggttgat tagtttctga cttttaaaaa acatacctgc
     8461 atattcacga tataacatta aaatgatatc tgacatttca tcaataattt cttgatggat
     8521 attcaatgaa ttcattttat ctattggtaa tttttgtaat acatctaata aatatagtgt
     8581 tttattcgat aatataactg catgtacatc tttagaagcc tcttgccttg aaatcgcacc
     8641 gtcaaactta aaactataac ctattaaatc tgcttgtgtg tcattaccac tcacagcaca
     8701 gcgattaaat gatgcagtaa aaccaaatcg tttcatacac tttaacataa ctacgactga
     8761 cattaactgt gcagatgtac ctgattctat tttttcaaga acaaattgta ataattgata
     8821 gttatatggt gcaatgtcac cttcatccat tgagcgctca atagtttcag ctgccagaga
     8881 ggcataactg cttacgtaaa ggtccatttg taatttataa tgttgactaa taacatctac
     8941 agaatttaac gttcccatac ctcgccactg attgtaaata aacaaaccat aaacaaacaa
     9001 ttgcgtttgc gcttgtaaac ccgtcttaac ttttttagca cgccttgcca taagtggtac
     9061 ttttgcacca tgctcattta aaatcgtgat aattttatca gattcaccat aatcaactgc
     9121 tttgatgata atcccttttt ggcgcattaa caattatctt caccactttt aagattaatc
     9181 ttggtcttca acataaccaa tttggcgaat aaagttaact ttgtttcgcc agtctctttg
     9241 aactttgacc cataattcta agtaaacttt agagcctaga agcatttcta tatcacgtct
     9301 cgcacgtttt cctacttctt ttaacttttt accgcctttt ccaatgacaa ttcctttttg
     9361 cgaatctctt tcaacatata tagttgcttc gatatgaacg cgatcttcgc tttctttaac
     9421 catacggtcc acattaacac caatcgcatg agggatttct tcacttgtaa gatgaaggat
     9481 tttttcacga atgatttcac ccactacaaa ttgttcagga tggtctgaaa tttgatcatc
     9541 tggataatat ttaggtcctt cgggtaaata cgtctttaaa acatcaataa aatgatcgac
     9601 atttagccct tctaatgctg aaataggtac aatctctgta aagtccatat aactttgata
     9661 ttcttcaatc tttggcatta attcatctgg atgcactaaa tctattttat ttaatactaa
     9721 aaatactggt gtcttaacat ttttcaacat ttctataata tattcatcgc ctcgtccaat
     9781 ttcctcattg gcattaacca taaacatgat tgcatctatc tcagataatg tatttttagc
     9841 gactttcatc atatagtcac ctaatttgtg tttaggttta tgaatacctg gcgtatcaat
     9901 gaatataatt tgcgcgtcat ctcttgtcat aacaccttga attttatttc tagttgtttg
     9961 agctttatcg gacatgattg ctattttatg gccgatcact ctattaacaa atgttgactt
    10021 tcctacattt ggtctaccta taattgaaac aaatcctgat ttatgttctg tcatttattc
    10081 taaatccttt cctgaaaatc caaatggtag taactctgcg actgtcatca taaccatatc
    10141 tcctttatga tttgtcatat acacaggcat atcatcatca cataattcct tcaaaacttg
    10201 acgacatgca ccacaaggtg atgacggttt atctgcatct acggttacag ttattgattc
    10261 aaaatcacct ggtctgtatc cttgagaaat tgccgatacc aaactagctc gttcagcaca
    10321 tatcgataat ggataagaag cattttctac attggtacca taaaaagttc taccgtcttt
    10381 cgtttttaaa taagccccta ctttaaattg actgtatggc gaatatgatt cttgttgtgc
    10441 ttttctaact tcttgaaaat aatgaggttg ataactcata tatgcctccc taaaataacg
    10501 ctataaaatg tggtaaaaat actattaaac ctataataaa tgctaatatt gaaactataa
    10561 gtacactaaa agccgcaata tctttagcgt atttagctaa atcatgatat tcaacggtca
    10621 ctaaatcgac aacatattca atagcagtgt ttaaagcttc aacagtgaga actaatgcaa
    10681 tagcaatgag tataaatatc cactcaatcc gattaatatt tagtacgaga ccaaagacaa
    10741 tagcaacaat cattgcaaac acatgtaaaa gaaatttata gtctttttga attaagattt
    10801 tcagcccatc aagtgcatat ttaaaccttt tcataattag tctcgtgtta atccatatgc
    10861 gtttaatatt gtatcttgtc gaccaaacat ttccttttca tccgcttcag tcatatgatc
    10921 ataacctaat agatgcaaaa atccatgtaa tgctaaaaat cctaattctc gttcaaaaga
    10981 atgtccgtaa ttgtttgctt gttcttgcgc tacatccgta cagataatta tatcccctaa
    11041 aacacgtggt atatcaagat cactaaaatc aatctctggc tcatcttctt ctaaagcaaa
    11101 tgagattaca tctgtaactt tatctttatc tctatatgtt cgattaattt cttgtatttc
    11161 ttgtttatct acaaatgtaa cagaaagctc agcatcgtct tctatatgct cttctttttt
    11221 agcaaattct aataaatctt caatttgttt ataccaagca tctttaacta agcctgtgtg
    11281 atcgctaaaa tctatcgtaa acatttaatt ctctccttca taatgttcaa tgatcttact
    11341 taccaatgga tgtctcacta catcgctctg atctaatttc aatatactta tacctttaac
    11401 gttgtgtaac ctactgaccg cttctttaag tccactttta acacctttag gtaaatcgat
    11461 ttgagtttgg tcaccagtaa ctaccatttt tgagccaaaa cctagtcttg ttaaaaacat
    11521 tttcatttgc gcatgtgtcg tattctgcgc ctcatcaaga attacaaatg catcttctaa
    11581 tgttcgtccg cgcatatatg caagtggcgc tatttcgata atgcctcttt caataaatcg
    11641 ctctgtttgt tcacgcccaa gaacagtata gagaccatca tataaaggtc ttaaatatgg
    11701 atctaccttt tctttcaaat ctcctggtaa aaatccaagt gactctcctg cttcaacagc
    11761 aggtcttgtt aatacaatac gtttaacagc acctttacgg agttgctttg ccgcataaac
    11821 tacagctaag aatgtcttac ctgtaccagc aggacctata ccaaatacta aatcattatt
    11881 tttcatggca ttaacatata tacgttgccc catcgttttc gcacgaatcg ttttaccaaa
    11941 tgcatcttta gttatctctt catcatataa atctaacaga tgttgaattg tgttattatg
    12001 cgccatttta atagctgctt caacatcttt aattgtaata ttattaccta aatcaataac
    12061 cttcagcaaa ttgattaata ctgattccgc tttttctacg ttttctattt ttgtaccttt
    12121 aacggcaact tcttgtcctc ttgcatggat gacaacatcg aaactctctt caattgcttt
    12181 taaatgttca tcattatttc caattaaagc ttgagattgg ttcatatcgt ctatttgtat
    12241 aattccaggc atacacgcgc tccttttcat atatcagtta tattgattct atgatgcttt
    12301 aatatctact taattatatc atgcaattga ttgatttaaa catctttgca ttgacttact
    12361 catttttctt taatttaaaa taatcattta tacttttcac cttgtcataa aagcagattc
    12421 aatattagac taatcaattt tttgttgtaa tttaaataac taatatttct cgaaagattc
    12481 tctttgtttt tcaatttttc ataacgtaaa aaaacaagca actaccatta cgatagtgct
    12541 tgttttcaaa aaattttata attgttttgg tttagctaaa atttctgacc atatcatacc
    12601 attgattact tcatctttat caaattggaa cgctgattta gtcaaatctt tttcgacatt
    12661 ttgagaatta agcaactgct ttaatttcaa acgttttgta cgttcagata agtatttatc
    12721 ctcaataata tctctagcac gtttttccat tttagcaatt tgcttttctt tttctctatc
    12781 aatgtcagta cgaatcgttt taatatcatc tctaagtgat ttttctaatt gacgtctaat
    12841 ttcgtcagaa ttatcttgtc tagaaggtct atgtttctgc tccaccggtt ctgctttagg
    12901 cactgtaatt ggtttctctg tcatcggttt tgtttctggt tgttttttag gtgccatagg
    12961 ttctacaaca ggtttcgatt taggctcttc ctttggaagt tcatcgaata aaggtggtaa
    13021 cgtatcatca tattttcgtt tcgatgattt cttttcttct tcatttaatt cttcacttat
    13081 ttctttaaac gttcgctcaa tttcttcaaa aaagccacct ttttttggtt cattatcggt
    13141 agatgttttt tgaggtggct tttgattttg tctatcttta tgactatttt cgcgcatagt
    13201 agtaatgata gaaatgatca ctgatatgac aaaaattaga ataccgacac tcatttaatc
    13261 acctctcgac ttaatgttca ggtgactcat catcactttg atcagttcgt ttattaattg
    13321 catttctcat gcctgtatca gcttcgatat ttttcaaatt ataataatct ttaacactga
    13381 tattgcctga gcgtaatgct tcagccatag ctaatggcac ttcagattcg gcttcaacta
    13441 ctttagcatg catttcttgt acacgcgctt tcatttcttg ctcagttgct acagccatag
    13501 ctctacgttc ttcagctttt gcttgtgcaa tatttttgtc tgctaatgct tgttcagttt
    13561 gtaagtctgc accaatattt ttactaatat caacgtcagc aatatcaatt gataaaattt
    13621 caaatgcagt acctgaatct aaacctttgc ttaatactgt tttagaaata ttatctgggt
    13681 tttcaagtac ttctgtatga tgcttactag aaccaattgt tgaaacgata ccttcaccaa
    13741 cacgtgcgat gattgtttct tcaccagcac caccaacaag tcgagcaata ttagctctaa
    13801 ctgtgatacg agctttggct ttcacttcaa taccgttcat tgctacacct gcgataaatg
    13861 gtgtttcaat gactttagga ttaacagaca tttgaaccgc ttctaatacg tcacgtcctg
    13921 caaggtcaat tgcagcagca cgttcgaaag gaagatcaat gtcagcacgt tgtgcagcaa
    13981 tattagcgtc aacaactctg tcaacatttc ctcctgctag ataatgcgat tctaattgat
    14041 ttgttgttaa tgctagtcct gctttatgcg ctttaattaa tggcgctata acttttcttg
    14101 gagatacacg acgtaaacgc ataccaacca atgtacctat accaacatga acgccagctg
    14161 ctaacgctga aatccataaa ccaatcggta caaatgagaa taaaataagt aatgcaacta
    14221 ctataataac tgctattacg ataaaactta aactaaacat ggtatcgctc cttttaatta
    14281 atctacttcc ctcacaacta ctcttgttcc ttcaacttca aggattttta ccgttttatt
    14341 gcgtaaaata aagttgccat ctgaaacagc atcaatacgt tcattttcac aaaaaataat
    14401 ccctgcaggt cgaagatctg taactgtttg agcagtcttt cctacgaggt gcgagcggtt
    14461 atcatgggaa ttgtaacctg actcagaatt agttgaatct tttaagataa ctttatccaa
    14521 aaacggaatc tttctgttga aaatcttcac taatatcacc cattctacaa tcgttaaaat
    14581 caaggcaacg ataacattcg caagcataaa tagcaaatta tcaccgagcg ttgttatgct
    14641 tatagttatc agtatcatgc caataatacc aattactgca ccaactacaa ataattcaat
    14701 tacaactaat ataacgccaa ttgagaatat taagatagaa tgcatattga catttccttg
    14761 gattagaaat cccaaaaata aaataagtaa tgataatgtg gcgataatac cagctgcatt
    14821 gattttttta gagtaaagtt gatatacaaa tcctaagaat gtcaaacagg ttaatattaa
    14881 cgtaaaaata ggttgaacaa ttatattact aacttgttca acccaagtat ctccagccgt
    14941 tgattccaag atagttgtca tttgtaaaaa attattataa ctcacaattt cacctcgccc
    15001 tcacattaat tatacatgaa attgaatata ctttatagtt ataagaacct atagaatatc
    15061 aatttgatta tttataaact atataacttt ttttaattaa aaattgacaa caaaaaaaca
    15121 tcacatatta gtgtcagaca ctaacttgtg atgtttgttt tatataatta atattcgtgt
    15181 tgagggagtc aacagaggta ttaattattt gaatttacgt ttacgtgcag cttctgattt
    15241 ctttttacgt tttacgcttg gtttttcgta aaattcacgt ttacgtactt cttggattgt
    15301 tccactttta gaaactgaac gtttaaatct acgtaacgca tcttcaagtg attcattttt
    15361 acgtactact gttttagaca tctgtatttc cctccctcca aatatcaacg gaactttata
    15421 gtcaattgca
//
LOCUS       DAPSKH010000064        13852 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPSKH010000064 DAPSKH010000000
VERSION     DAPSKH010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13852)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13852)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13852
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.064"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(139..386)
                     /locus_tag="RPH49_002218"
                     /pseudo
     CDS             complement(139..386)
                     /locus_tag="RPH49_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239616.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sphingomyelin phosphodiesterase"
     gene            775..2823
                     /gene="eap"
                     /locus_tag="RPH49_002219"
                     /gene_synonym="map"
     CDS             775..2823
                     /gene="eap"
                     /locus_tag="RPH49_002219"
                     /gene_synonym="map"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular adherence protein Eap/Map"
                     /protein_id="HDY5125343.1"
                     /translation="MKFKSLITTTLALGVLASTGANFNTNEASAAAKPLDKSSSTLHH
                     GHSKIQVPYTITVNGTSQNILSSLTFNKNQQISYKDLENKVKSVLYFNRGISDIDLRL
                     SKQAEYTVHFKNGTKKVVDLKSGIYTADLINTSDIKAISVNVDTKKQPKDKAKANVQV
                     PYTITVNGTSQNILSSLTFNKNQNVSYKDLEDKVKSVLESNRGITDVDLRLSKQAKFT
                     VNFKNGTKKVIDLKAGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLN
                     GTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGG
                     KRVVHFNSKTYSANLVHAKDVKKIEVTVKTASKAKAERYVPYSIAVNGTSTPNLSDLK
                     FTGDPRVGYKDITKKVKSVLKHDRGIGERELKYAKKATYTVHFKNGKKKVINLNSKIS
                     QLNLLYVQDIKKIDIDVKTGSKAKADSYVPYTIAVNGTSTHILSKLKISNKQLIGYQD
                     LNEKVKSVLKHDRGINDIELKFAKQAKYTIHFKNGKTQVVDLKSDIFTRNLFSAKDIK
                     KIDIDVKQHTKSKKINKSNNVKFPVTINKFENIVSNEFVFYNASKITINDLSTKLKSA
                     MANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDRKVFKATDIKKVDIELKF
                     "
     gene            complement(3102..4388)
                     /locus_tag="RPH49_002220"
     CDS             complement(3102..4388)
                     /locus_tag="RPH49_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDY5125344.1"
                     /translation="MNPLAQSLNEQIQQSNATAFAMLSDLGQNMFYPKGILSQSAEAK
                     STTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRD
                     NPELSIDNMSRPIVTNALTHGLSLVGDLFVNQGDTILLPEHNWGNYKLVFNTRKGANL
                     QTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHKEVTTIVDAIKA
                     LADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALTNLHSNAILPVRLDGATKEFFAWGF
                     RVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDHEIEQN
                     IQTLKERYEVTKKVVYADQYRSYWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIG
                     VIALSATDIRIAFSCVEKDDIPHVFDSIAKAIDDLR"
     gene            4588..4686
                     /locus_tag="RPH49_002221"
     CDS             4588..4686
                     /locus_tag="RPH49_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125345.1"
                     /translation="MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK"
     gene            4929..5087
                     /locus_tag="RPH49_002222"
     CDS             4929..5087
                     /locus_tag="RPH49_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125346.1"
                     /translation="MKHLTKIFVVLAIILFIIGYYLQATNHESQGIKLLLAAIMFMIC
                     AFISRSND"
     gene            5364..5744
                     /locus_tag="RPH49_002223"
     CDS             5364..5744
                     /locus_tag="RPH49_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5125347.1"
                     /translation="MKIILKNNSDFPIYEQIKQQVKQNILKGHVVPGEHLPSMRELAK
                     DLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNE
                     AQAIEMSLEELQDILTFIYEEESS"
     gene            5741..6637
                     /gene="pmtA"
                     /locus_tag="RPH49_002224"
     CDS             5741..6637
                     /gene="pmtA"
                     /locus_tag="RPH49_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     ATP-binding protein PmtA"
                     /protein_id="HDY5125348.1"
                     /translation="MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTI
                     IRLIMDLYQPQTGVIRVLEEDMALNPIELKNRIGFVYAENYFNERWTTKQLEKMIAPF
                     YSNWDHQVFQFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLD
                     PLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQ
                     RYQVVSGALEDLDEELAALLIYEEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENL
                     MVYLEKRKPKYHENIKLMEEGF"
     gene            6638..7318
                     /gene="pmtB"
                     /locus_tag="RPH49_002225"
     CDS             6638..7318
                     /gene="pmtB"
                     /locus_tag="RPH49_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     permease subunit PmtB"
                     /protein_id="HDY5125349.1"
                     /translation="MKALLIRNFKLRRYTLIIYVLLLTLYPFYIMLDSTKFFYLLQSF
                     ISPTILIIWILDAGHLFRLNRRLGGNDSYYFYMSLPVSKKQLLNANYITCIVLTLIGT
                     LVISLYAYEANVIEPNSIYFSTAYAFVISNFLSIPIAFSQFTELRRVKVPYGIYVFTI
                     IILVPFLFSIAIVLVNYFVLSQSSFPDLYSYILNIGFLIISIVILIVNYFKQLNKINT
                     RKFKGGSR"
     gene            7315..8187
                     /gene="pmtC"
                     /locus_tag="RPH49_002226"
     CDS             7315..8187
                     /gene="pmtC"
                     /locus_tag="RPH49_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     ATP-binding protein PmtC"
                     /protein_id="HDY5125350.1"
                     /translation="MKLEHITKKYGSNVVLNDIDFDFGDSRIVGLIGKNGVGKTTVMK
                     VMNGNIIKFDGKVDIDNADNIGFLIEHPKLYDNKSGLYNLKLFAQVLGKGFDKAYTDK
                     IIDAFGMRPYIKKKVKKYSMGMKQKLAIAVSLMNKPKFLILDEPTNGMDPDGSIDVLT
                     TIKSLVNELDMRILISSHKLEDIELICDRAVFLRDGHFVQDVNMEEGVASDTTIVTVD
                     HKDFDRTEKYLAEHFQLQNVDKADGHLMINAQKNYQVILKALSELDIYPKYIETRKSS
                     LRDTYFNINQRGDK"
     gene            8187..8927
                     /gene="pmtD"
                     /locus_tag="RPH49_002227"
     CDS             8187..8927
                     /gene="pmtD"
                     /locus_tag="RPH49_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenol-soluble modulin export ABC transporter
                     permease subunit PmtD"
                     /protein_id="HDY5125351.1"
                     /translation="MRILNLVKYDFYSIFKSPLTYLAILVVSSLIATQSILMANSMDN
                     PKHIIVYGSVFAAAKWLLLIIGLMFVVKTITRDFSQGTIQLYMSKVKTRVGYIISKTI
                     SIILISILFAVIHYVILIVVQASSNGKNLAFSKYVDNLWFFLIFLLFFGLFLFLITLA
                     SQKTAMIFSLGVFLVLIVPFIKPFITFIPRYGEKVLDAFDYIPFAYLTDKMISSNFDF
                     SNWQWVISLGSIVIFFILNILYVAKKDI"
     gene            complement(8993..9556)
                     /locus_tag="RPH49_002228"
     CDS             complement(8993..9556)
                     /locus_tag="RPH49_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDY5125352.1"
                     /translation="MTNLETYFKNSQPLNEYIDGMKTNQDTVLSIYQSFELPEDDSRI
                     KKIKEMNYSKVLVITEDWCGDAMMNLPILKHISEALNLEVRVFHRDDDTKLIDQYLTN
                     GKSRAIPIFVFLNDQFEQETVWGPRANEVQKFVTDVRSDKLPSKDHPDYADLEKETHL
                     VISNRYKTDASFWKAVYNSILNKLENK"
     gene            9677..10201
                     /locus_tag="RPH49_002229"
     CDS             9677..10201
                     /locus_tag="RPH49_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125353.1"
                     /translation="MLYLNKYKERVTSVRIQNRWVVFILFLICSFGVLIGLYQYRHTK
                     TVDLSNLEINDIKLNEKFDKKGYEVNKKIKFDRFKFYNSKAHPDLTVKVREKDNIVKG
                     IILVRDEKIHTNFDGGIGSPINNAIENLGFGYKRTKVGNDFSSVKYIDRDNHLKLNLL
                     YQDLEIKRIEFFSK"
     gene            10261..10818
                     /locus_tag="RPH49_002230"
     CDS             10261..10818
                     /locus_tag="RPH49_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001669025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDY5125354.1"
                     /translation="MNKITYLNELETALDALPRHLRDQKMYEYERYFYEQELNGVDEE
                     EILKKLKDPQDVAAETKARSVIDYAESKPTFENISRAVAASLSLGILSIFVILIPVSI
                     VGLFVLALFLISLLLLFCPIILLASAISRGIVDSISNVFFAISYSGLGLVFIIVIFKI
                     LEYIYRLILKYLLWYIKTVKGSVRK"
     gene            10815..11657
                     /locus_tag="RPH49_002231"
     CDS             10815..11657
                     /locus_tag="RPH49_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDY5125355.1"
                     /translation="MKKFFFIGLLVFVVFFTAATIIWFSYDKNKYGTKQYDKTFKDDA
                     FDNVSINLDSTELRIKRGNQFRVKYDGDNDILINIVDKTLKISDKRSKTRGYAIDMNP
                     FHENKKTLTIEMPDKMIKRLNISSGAGSVRISDVDLENTSIQSINGEVVIKNSNLDAL
                     DSKTNNSSTYISKSNIKNSNIKVVIGTLQIDKSQIKQSIFLNDHGDIEFKNMPSKVDA
                     KASTKQGDIRFKYDSKPEDTILKLNPGTGDSVVKNKTFTNGKVGKSDNVLEFYTIDGN
                     IKVE"
     gene            complement(11714..12754)
                     /locus_tag="RPH49_002232"
     CDS             complement(11714..12754)
                     /locus_tag="RPH49_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDY5125356.1"
                     /translation="MQQVTSDIMTFRGSHFELGVKTGKWLQQTPLLKNREKEWKKRVP
                     RFDIDVNETYQIFQTYAPQIWEELMGLQSILKMPTRQIILNFGHYRFTDLKESGCTVF
                     QGKDFMVRNYDYHPATYDGRYLLYQPTDSGLAQIGPVSRVTGRMDGMNESGLTMGYNF
                     MHRKKPANGFVCYMIGRLILENCRNVTEAIQLLKEIPHRSSFSYILMDKSLNHAIVEV
                     TPRSIDVRYDNICTNHFEILTHENRNYTKESKERLARTISQTNDNLDMTTAFKLFNNP
                     QYEIYSKLFKSWSGTIHTSMYHPETLTAYFTLGENAPPEIIDFKSWLDGQELNITHFT
                     GNIDTDLTFANK"
     gene            13205..13378
                     /locus_tag="RPH49_002233"
     CDS             13205..13378
                     /locus_tag="RPH49_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125357.1"
                     /translation="MWNFIKCVFKFVFSLVAITTLVAGVGVVAFAYIFKKDFEDIERK
                     TKEIISDIESKNN"
     gene            complement(13435..13740)
                     /locus_tag="RPH49_002234"
                     /pseudo
     CDS             complement(13435..13740)
                     /locus_tag="RPH49_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500634.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YolD-like family protein"
BASE COUNT         4959 a         1793 c         2281 g         4819 t
ORIGIN      
        1 gtctagcttt tggggtgtac attccacaca aacatgtgat tattttgatg tttctattaa
       61 acttgtaatt ttaaatttaa agtccctaaa aagtccctaa aattttattt tatatgaggt
      121 attattgata atgataaagt tataaacctt gatattatgc tgttttactt tttgaatgat
      181 aagtaatttt atgttaaaag tctccagttt ggatacaaaa cggtcgataa catataaacg
      241 ttatgactga ctaattttaa atcagtatca tctttcttag tttctgcttt ggcactattg
      301 tcagtaagtg caccaactaa taataaattt gctaatgcaa gtgttgcaac tttttttagt
      361 gaattggatt ttgttttttt caccatcatt atcactcctt ttatatagct tacaataaaa
      421 tagtcacaaa attgattaac taaaattaaa ttaattatta aatcgaattt atatttttaa
      481 gcaaatgctt tttatatatt aagacaatgt aaacatatta gataaataaa gtcggaatta
      541 agggttagag gcgagtaagc catttacatt taaggcttaa catccataaa agcaaacaac
      601 ttttttgcaa ctaagaattt agcagttaat caaaattaaa agaactttta actgtattaa
      661 agaattgttg ttaaagataa tttattatta atattcagtt aattcaaaaa acggagcaga
      721 cctggctata ataaagttgc aatcacgaat tacataaaaa aggagagata atttatgaaa
      781 tttaagtcat tgattacaac aacattagca ttaggtgttt tagcatcaac aggagcaaac
      841 tttaatacta acgaagcatc tgccgcagct aagccattag ataaatcatc aagtacatta
      901 caccatggac attctaaaat ccaggttcca tatacaatca cagtgaacgg cacaagccaa
      961 aacattttat caagcttaac atttaataag aatcaacaaa ttagttataa agatttagag
     1021 aataaagtta aatcagtttt atactttaat agaggtatta gtgatatcga tttaagactt
     1081 tcaaagcaag cggaatatac ggttcatttt aaaaatggaa caaaaaaagt tgtcgatttg
     1141 aaatcaggta tctacacagc tgacttaatc aatacaagtg acattaaagc tatcagtgtt
     1201 aacgtagata ctaaaaagca acctaaagat aaagctaaag caaatgttca agtgccgtat
     1261 acaatcacgg ttaatggtac aagccaaaac attttatcaa gcttaacatt taataagaat
     1321 caaaatgtta gttacaaaga tttagaggat aaagttaaat cagttttaga gtccaataga
     1381 ggtataactg atgtagattt aagactttca aaacaagcga aatttacagt taattttaaa
     1441 aatggaacga agaaagttat agatttgaaa gcaggtattt acacagcgaa tttaataaat
     1501 tcaagtgata ttaaaagtat caatattaac gtagatacaa aaaaacatat cgaaaataaa
     1561 gctaaaagaa actatcaagt tccatattca attaatttaa atggtacatc tacaaacatt
     1621 ttatcgaacc tttcattttc aaataaacct tggacaaatt acaaaaattt aactagtcaa
     1681 ataaaatcag tactgaagca tgatagaggt attagtgaac aagatttaaa atatgctaag
     1741 aaagcttatt atactgttta ttttaaaaat ggtggtaaga gagtggtaca ttttaattca
     1801 aaaacttact cagcgaatct agttcatgcg aaagatgtta agaaaattga agttacagtt
     1861 aaaacagcat ctaaagcaaa agcggagcgt tatgtaccat actcaattgc agtaaatggt
     1921 acatcaacac caaatttatc agatttaaaa tttacaggtg acccacgtgt aggctacaaa
     1981 gatatcacta aaaaagttaa atcagtattg aagcatgata gaggtatcgg ggaacgtgaa
     2041 ttaaaatatg caaaaaaagc aacttacaca gtacatttta aaaatggaaa gaaaaaagtg
     2101 attaatttaa actcaaaaat tagccaactg aatctacttt atgttcaaga tattaaaaag
     2161 atagatatcg atgttaaaac aggatcaaaa gcgaaagcag atagctatgt accatataca
     2221 attgcagtaa atggtacatc aacacatatt ttatcaaaac taaaaatttc aaataaacaa
     2281 ttaataggtt atcaagattt aaatgaaaaa gttaaatcag ttttaaaaca tgatagaggt
     2341 atcaatgata ttgaattgaa atttgcgaaa caagcgaagt atactataca ctttaaaaat
     2401 ggaaagacac aagttgttga ccttaaatca gatatcttta caagaaactt attcagtgcc
     2461 aaagatatta aaaagataga tattgatgta aaacaacaca ctaaatcaaa aaaaataaat
     2521 aaatctaata atgtgaaatt cccagtaaca ataaataaat ttgaaaacat agtttcaaat
     2581 gaatttgtgt tctataatgc aagcaaaatt acaattaatg atttaagtac aaaacttaaa
     2641 tcagcaatgg caaatgatca agggattact aaacatgaca taggacttgc tgaacgcgcg
     2701 gtgtataaag tgtattttaa aaatggttcg tcaaaatatg tagacttaaa aactgagtat
     2761 aaagatagaa aagtatttaa agcaactgac attaaaaagg tagatattga acttaaattc
     2821 taatctttaa ttttataata aggcatctca caatcgtggg gtgcctttta catttgtaga
     2881 gatgtggtgc ttgaatgctt gaagtgattt gccaaaagtt atataaattt gcaccaaata
     2941 aattaagttt tgttaggaga gatgtataaa actaattagg tatagcgttt gacaagttgc
     3001 tgaataaaat atatcttatg atgctttaaa agaaggaata attttaaaaa taaaaaacca
     3061 ataatccgag tcatattcat cagattattg gttgaagtta attatcttaa gtcatctatc
     3121 gctttagcaa ttgaatcgaa gacatgtggg atatcgtctt tttctacaca gctaaatgca
     3181 atacgaatat ctgttgcact tagtgcaata acaccaattg aatatttttc aattaaatgt
     3241 ttacgaagtt cttcagggtc aacatcatga acttttattg ccataaagta tccagagtta
     3301 aagtcatatg cttgccaata tgatcggtat tgatcagcat agactacttt cttagtgact
     3361 tcatagcgtt cttttaatgt ttgaatattt tgttcgattt cgtgatcgaa ttgcttatta
     3421 tttttcagta catgtttaac agcgctttgt gttggaagcg gtccgctgga aatattgctt
     3481 ctaataagac cttttacttt ggcttctaat acttctttag ttgtttgatc agacgttcca
     3541 aatgtcataa atccaacacg gaatccccat gcgaaaaatt cttttgttgc accatctaaa
     3601 cgaacaggta atattgcatt tgaatgtaaa ttagttaatg cagtaaataa tgattgagta
     3661 tacacatctt catagaataa accatagtat gcatcatcca caacagctat aacttttgta
     3721 cctttatcag ctaatgcttt aattgcatcg acgatggtag tcacttcttt atgcgtaggt
     3781 gtgtaacctg tcggattatt aggataattt aaaatcataa tgactttatc tttattgtat
     3841 gattgtaaag cttctactag tgaatcagta gtataatgtc cgtctttatc aaagatagga
     3901 tatgtttgaa ggtttgcacc ttttctcgta ttgaaaacaa gtttgtaatt accccaatta
     3961 tgctctggta acaagatagt gtcaccttga tttacaaata aatcgccaac tagagataaa
     4021 ccatgtgtta atgcattcgt aacaattggt cgtgacatgt tgtcgattga tagctctgga
     4081 ttgtcacgca acattttttg ttgccataaa tcacgtaatt cttcgatgcc ttgtggtggc
     4141 gcataaggga atatttcatc tggagttaaa tcattaaaca ttgcatctaa agatgatgca
     4201 aacatttttc cgtctttgtt tgtcgccata cctatagttg cattatatgt tgtactcttt
     4261 gcttcagcag attgagataa aatgcctttt ggataaaaca tattttgacc taagtcagat
     4321 aacattgcaa aggcagttgc atttgactgt tgaatttgtt catttaagct ttgggctaaa
     4381 ggattcatta ttgcttaacc tctctttaaa aaaattgtat gcctatatat tatcttcaat
     4441 tataccaaat ataaagtgtt gttggtgaat taacgaataa tatgtaaaat ctgctaccaa
     4501 aatacgaaca tatgttctgt ttttgtgtta gaatatgtat aggtcatcct tcagtatgat
     4561 actttagtcg aacggaggtg tagtgtaatg atgtggtggc aagaagggat gatgacactt
     4621 attacaggtg gcttactaat tatttttcga ctttggttag aactgaaatg gaaaaataaa
     4681 aaatgatcct acacacataa ataaccccaa gtctgctggt accagacttg gggttgtgta
     4741 gtataattct gtggatacac ttaaataata tcattgaaca caatatatcg caatcaataa
     4801 tcattttgat tgaatggttt tgttgcgcta ttttagttga aagtgattag taccttgaac
     4861 ttttgaaatt caataactta ttaaaaaaat ttatatttgt tataatgtcg atgttgaggt
     4921 gaaataaatt gaaacatcta acaaaaatat ttgtagtact tgcaattatt ttatttatta
     4981 ttggttatta tttacaagca actaatcatg aaagtcaagg tataaaatta ttattagcag
     5041 cgattatgtt tatgatttgt gcttttataa gtagaagtaa tgattgacgt aaaaatagta
     5101 aataggattg actgtttaaa acgattgttt atgttgacgc tacggttgtc acgtagagat
     5161 taaagacatt cgttttagca gtctttttta ttgaagtaga caatgcaaga ttaaatggta
     5221 gtgtcatttc attttattca actgctagta atacaatact cagtgttatt tctgaagact
     5281 ggttgataat gagacatgca tatttacaaa actgtgtata ttgtgtatat tgtatatata
     5341 cagaaggcga tagggggacg ttgatgaaaa taattttaaa aaacaatagt gattttccga
     5401 tttatgaaca gattaagcaa caagtaaaac aaaatatttt aaagggacat gttgttcctg
     5461 gagagcattt gccgtcaatg agagaacttg ccaaagatct tcaagtaagt ttgattacta
     5521 ccaaacgtgc ttatgaagat ttagagaaag acggttttgt tacaacaatt agaggaaaag
     5581 ggacctttgt taaggagcaa gatagttcta ttttaaaaga gaaacaattt tttaccattg
     5641 aaaatttggt taaagaattg gttaatgaag cgcaagcaat cgaaatgtca cttgaggaac
     5701 ttcaagatat tttaacgttc atctatgagg aggaatcatc atgaatgcca tagaattaag
     5761 taatgttaat tattcaagtg atcagtttaa tttaaagaat atctctttca aagttcctca
     5821 aggtttcgtc actggtttta ttggtagaaa tggcgctggt aaaaccacaa taataaggtt
     5881 aattatggat ttgtatcaac cacaaactgg tgttattaga gtattagaag aggatatggc
     5941 tctcaatccg atagagttaa agaatagaat tgggtttgtt tacgctgaaa attattttaa
     6001 tgagagatgg actacgaagc aacttgaaaa aatgattgcc cctttttata gtaactggga
     6061 tcatcaagta tttcagtttt atcttgaaaa gttcgattta ccaatcaata aatcaataaa
     6121 aacattttca actggcatga aaatgaaatt atcattagca gttgcatttt cacatcatgc
     6181 tgaattgtat atttttgatg agcctacttc aggtcttgat cccttagcta gaaatgagtt
     6241 attggagata attcagcaag aattaattga tgaaaataaa acaatattca tgtcgacaca
     6301 cattatctca gatttagaaa aaatagctga ttatatcatt cacttaagtg acggtgaagt
     6361 tatcttaaat ggttcaaaag aacaactgtt acaaagatat caagttgtga gtggagccct
     6421 tgaagattta gatgaagaat tggctgcttt gctgatttac gaagaacata agcgtacggg
     6481 atttatagga ttaacagaac atgcacaagt atttaaagaa attttaggtc ataaagtgaa
     6541 tatcactaca ccttctattg agaacttaat ggtttatctt gaaaagagaa aacctaaata
     6601 ccatgaaaac atcaaattga tggaagaagg tttttaaatg aaggcattgt taattaggaa
     6661 ttttaaatta cgacgatata cacttatcat ctatgttcta ttattaacct tatatccttt
     6721 ttatataatg cttgactcaa caaagttctt ttacctattg caatctttta taagtccaac
     6781 aatattgatt atttggattt tagatgctgg tcacttattt agactcaatc gtagattagg
     6841 tggtaatgat tcatattatt tttatatgag tttaccagtg tcaaaaaaac aattgcttaa
     6901 tgccaactat attacatgca ttgttttaac attaattgga acgcttgtta ttagtttata
     6961 tgcttatgaa gcaaatgtga ttgaaccaaa ttcaatctat ttttcaactg catatgcatt
     7021 tgtcatatct aacttcttgt ctataccaat tgcatttagt caatttacag aattgcgtag
     7081 agtcaaagtg ccatatggta tatacgtgtt tactattatc attttagttc catttttatt
     7141 ttcaattgca atagtgttgg tgaattattt tgttctaagt caatcatcat tcccagattt
     7201 atattcatat attttaaata ttggttttct aattataagc attgttatac ttattgttaa
     7261 ttattttaaa cagctcaata aaataaatac tagaaaattt aaaggaggca gtcgatgaaa
     7321 ttagaacata ttacaaaaaa atacggctca aatgtcgttt taaatgatat tgattttgac
     7381 tttggcgata gtagaattgt cggattaata ggaaaaaacg gtgttggtaa aacaaccgtt
     7441 atgaaagtaa tgaatggtaa tattattaaa tttgatggaa aagtagacat tgataatgca
     7501 gataatatcg gttttttaat tgagcatcct aaattatatg ataataaatc aggattgtat
     7561 aacttgaaat tatttgcaca agtattaggt aagggttttg ataaagcata cacagacaaa
     7621 attatagatg catttggtat gagaccttat attaaaaaga aagttaagaa atattcaatg
     7681 gggatgaagc aaaagttagc aattgcagta tctttaatga ataaacctaa atttttaatc
     7741 ttggatgagc ctacaaatgg tatggatcca gatggctcaa ttgatgtgct gactacaatt
     7801 aagtctctag taaatgaact tgatatgaga attctaatat caagtcataa gttagaagat
     7861 attgaattaa tttgtgatag agctgtattt ttaagagacg gacattttgt tcaagatgta
     7921 aacatggagg aaggtgttgc atctgacaca acgatagtta ctgttgatca taaagacttt
     7981 gatagaactg aaaaatatct tgcagagcat ttccaattac aaaatgtcga caaagcagac
     8041 ggacatttaa tgatcaatgc acaaaaaaat tatcaagtta tactaaaagc attatctgaa
     8101 ttagatattt atccgaaata tattgaaaca cgtaaaagtt cattgcgtga tacgtacttc
     8161 aatataaatc aaagaggtga taaataatga gaattttaaa tttagttaag tatgattttt
     8221 atagtatatt taaaagtcct ttaacatatt tagcgatact agtcgtatct agtttgattg
     8281 caactcaaag tatacttatg gcaaattcga tggataaccc gaaacatatt attgtctatg
     8341 gatctgtatt tgctgcagca aaatggttat tgttaataat tggattaatg tttgttgtta
     8401 agacaattac gcgtgatttt tcacaaggta caattcaact atatatgagt aaagttaaaa
     8461 cacgcgttgg atacattatt tcgaaaacaa tttcaattat tttaatttca atattatttg
     8521 cagtaattca ttatgtgatt ttgattgttg tgcaggcatc tagtaatgga aaaaatttgg
     8581 cgttttctaa atatgtagat aatttatggt tcttcctaat ctttttacta ttctttggct
     8641 tgtttttatt cttaatcaca cttgcatcac aaaaaacagc aatgatattt tcattaggtg
     8701 tatttttagt actcattgta ccgtttatta aaccttttat tacatttatc ccaagatacg
     8761 gtgaaaaagt tttagatgct tttgattata tcccttttgc ttacttaact gataaaatga
     8821 ttagctctaa ctttgatttt agcaattggc aatgggtaat ttcattaggt tctatagtga
     8881 tattcttcat tttgaatatc ttatatgtcg ctaaaaaaga catttaataa aaataatttt
     8941 gaggttggga attttaaatt ttcccaacct caaagtttgt cttattgtaa atttatttat
     9001 tttctaattt atttaggatg gaattataaa ctgctttcca aaatgaagcg tcagttttat
     9061 agcggtttga tataactaag tgtgtttctt tttctaaatc tgcatagtct ggatgatctt
     9121 tgctcggtaa tttatcagaa cgaacatcag ttacaaattt ttggacttca tttgctcttg
     9181 gtccccaaac tgtttcttgt tcgaattgat cattcaagaa tacgaagata ggaattgcac
     9241 gtgatttacc atttgttaaa tattgatcga tcagttttgt atcatcatct ctatggaaca
     9301 cgcgtacttc taaatttaat gcttcactga tgtgttttag aattgggaga ttcatcattg
     9361 catctccaca ccagtcttca gtaattacta atactttaga ataattcatc tcttttattt
     9421 ttttgatgcg tgaatcatct tctggtaact caaatgattg atagatactg agaacggtat
     9481 cttgatttgt cttcattcca tcaatgtatt catttaaggg ttggctattt ttgaaataag
     9541 tttctaaatt tgtcattgta aaaacctcct ttagcattta caacattata ccaatttata
     9601 gtaataaaag gtaatgaaat aaattaattg caaattcttt gttaattttt gttaaggatg
     9661 aaacgggaag caccttatgc tatatttaaa taagtacaaa gaaagggtga catcagtgcg
     9721 tattcaaaat cgctgggttg tgtttatatt atttttaatc tgttcttttg gtgtattaat
     9781 tggtttatat caatatcgtc atacgaaaac tgtggatttg tctaatcttg aaataaacga
     9841 tattaaatta aatgagaagt ttgataaaaa aggctatgaa gtaaataaaa aaattaagtt
     9901 tgatcgtttt aaattttata acagtaaagc tcaccctgac cttaccgtta aagtgagaga
     9961 aaaggataac atcgttaagg ggataatatt agtaagagat gaaaagatac atactaattt
    10021 tgatggggga attggttcgc cgataaataa cgcgattgaa aatcttgggt tcggatataa
    10081 aagaacaaaa gttggcaatg atttctcatc ggtaaagtat attgatagag ataaccattt
    10141 aaaattaaac ttactttatc aagatttaga aattaaacgt attgaatttt ttagtaaata
    10201 gctttaggtc ttaaagttat aaaaaacgaa tgaataattt tattgggatg agtgacctat
    10261 atgaacaaga ttacttattt aaatgaatta gaaacagcac ttgatgcgct acctaggcat
    10321 ttaagagatc aaaaaatgta tgaatatgaa cgttattttt atgagcaaga acttaatggc
    10381 gttgatgaag aggaaatttt aaagaagtta aaagacccac aagatgttgc agctgaaaca
    10441 aaagctagaa gtgttattga ttatgctgaa tctaaaccaa catttgaaaa tatttcaaga
    10501 gctgttgctg cttcattaag tttaggcatt ctatctattt ttgtcatcct tataccagta
    10561 tctatagttg gattatttgt attagcatta tttttaatat cacttttgct gctgttttgt
    10621 ccaattattt tattagcatc agcaatatcc agaggaattg tagactcaat tagtaatgta
    10681 ttttttgcca tatcatattc aggattagga ttagtattta tcattgtcat atttaagatt
    10741 ttagaataca tttatcgttt aatcttaaaa tatttacttt ggtatattaa aactgtcaaa
    10801 ggaagcgtta gaaaatgaag aaattctttt ttattgggct tttagtgttt gttgtctttt
    10861 ttacagcagc aaccattatt tggttcagct atgataaaaa caaatatggt actaaacaat
    10921 atgataaaac attcaaagac gatgcttttg acaatgtatc tataaatttg gatagtacag
    10981 aacttcgtat aaaacggggg aatcaattta gagttaaata tgatggtgac aatgatatat
    11041 taattaatat agtagataag acgttgaaga ttagtgataa aaggtctaag acaagaggat
    11101 atgcaattga tatgaatcct tttcatgaga ataagaaaac tttaacgatt gaaatgcctg
    11161 ataaaatgat taaacgttta aatatatcgt ctggagcagg aagtgttaga atcagtgatg
    11221 ttgatttaga gaacacaagt attcaaagca ttaacggtga agtagttatt aaaaactcaa
    11281 atcttgacgc actagattca aagacaaata atagttctac ttatattagt aaaagtaaca
    11341 ttaaaaatag taatattaaa gttgttattg gtacgctaca aatcgacaag agtcaaatta
    11401 aacaatccat atttttaaac gatcatggtg acattgaatt taaaaacatg ccatcaaaag
    11461 tagatgcaaa agcttctact aaacaaggag atattcgttt taagtatgat agtaaacctg
    11521 aagacactat actaaagcta aatccgggaa cgggtgatag cgtagttaaa aataaaacat
    11581 ttactaatgg taaagttggg aaaagcgaca atgttttaga attttatacg attgatggta
    11641 atatcaaagt tgaataaata aaggatgtaa gcaccgatat taggaagcat aatttctcta
    11701 atatcggtgt tatttatttg ttggcaaaag ttaagtcggt atctatattg ccagtaaagt
    11761 gagtgatatt aagctcttga ccatctaacc atgatttgaa atctattatt tctggtggcg
    11821 cattttctcc caatgtaaaa tatgcagtta atgtttcagg gtgatacatt gatgtatgga
    11881 tggtgccaga ccagcttttg aatagtttac tgtaaatttc atactgagga ttattgaata
    11941 acttaaatgc tgtagtcata tctaaattat cattagtttg tgaaatggta cgcgccagtc
    12001 tttctttaga ttcttttgta taattgcgat tttcatgtgt taatatttca aaatgatttg
    12061 tacatatatt atcataacga acatctattg atctcggcgt cacttcaaca attgcatggt
    12121 tcaatgattt gtccatcagt atgtagctaa atgagcttct gtgtggtatt tctttcaata
    12181 attggattgc ttctgttaca tttcggcaat tttcaagaat tagacgacca atcatataac
    12241 atacaaaacc atttgctggt ttcttccggt gcataaagtt atagcccata gttaatcctg
    12301 actcattcat accatccatt cttccagtta cccttgatac aggaccaatt tgagctaaac
    12361 cgctatctgt aggttgatat agtaagtagc gaccatcata agttgcaggg tggtaatcat
    12421 aatttctaac catgaagtct ttgccttgaa agaccgtgca accactttct tttaaatcgg
    12481 taaaacgata atgtccaaag tttaaaataa tttggcgtgt tggcattttg agtatacttt
    12541 gtagtcccat taattcttcc catatttgag gtgcgtaagt ttggaatatt tgataagttt
    12601 catttacatc tatatcgaaa cgtgggacac gttttttcca ttctttttct cgatttttta
    12661 gaagaggtgt ttgttgaagc catttaccag ttttaacacc taactcgaaa tgtgaacctc
    12721 taaaagtcat aatatctgat gtcacttgtt gcatatcatc ggcccctttc tttttagttg
    12781 taatatattg taaataaata gtaatcgtat gtatattgaa tgtcatgtta aataaagtta
    12841 tattttacta aatgaaatat aaaattgttt gaggtgattt ctcggtgtat aagacttatc
    12901 aatcagttaa aacatatttt tatagatggt ggggatatta agttaaaaac ttaaaatcat
    12961 cttatcataa ataacaatct taagttagca ttcacgataa tagtcattgt taacattagc
    13021 atataaggtc atgtcacgtt gaaacagagg ttcctcggca tttttgaaaa taatcattag
    13081 cttgctcgct atataatttg atgaatatat ttcgtaaaag tgggtattta tttaatgatt
    13141 attctatata tgatagtata atgaaatgta gataggtatt taatttaaca gaggtgaaat
    13201 tgagatgtgg aattttatta aatgtgtgtt taaattcgta tttagcttag ttgctattac
    13261 aacattagtt gctggtgttg gtgtagtagc atttgcttat atctttaaaa aagattttga
    13321 agatattgaa agaaaaacta aagaaattat ttctgatatc gaaagtaaaa ataactaata
    13381 acatttaggc aaggacaata tagattgttc ttgcctttaa ttatgttcaa agcattaagg
    13441 taacaagaca atatctaaga tatcaaagat agaaattttt tgacgttgtt gctgattgta
    13501 aacataacca tcaatttcat aattaatagc atcaatacga taaatggtta agcgtactga
    13561 atctacaaag ccattattat aaaatttaac ttctacaggt tgggcatatt gtagcgcctc
    13621 gtgtagccga atgtttagct cagccaattg atcatctgat aatacaggac gtgtaatttt
    13681 gttttggtcg ataatgtatt gttgaatcgt ttcgaattgt tcgggtaatg ttgcaaaagg
    13741 ttatatatat attgaagaat atagactatt ttgtttaaaa tgaatcatat tttaagaaaa
    13801 aatgaacaaa gtaaaaatat taaatagtct ttttttatta cgtgtaataa gt
//
LOCUS       DAPSKH010000065        13669 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPSKH010000065 DAPSKH010000000
VERSION     DAPSKH010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13669
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.065"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..376)
                     /gene="sarU"
                     /locus_tag="RPH49_002235"
     CDS             complement(<1..376)
                     /gene="sarU"
                     /locus_tag="RPH49_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarU"
                     /protein_id="HDY5125358.1"
                     /translation="MDYQTFEKVNKFINVEAYIFFLTQELKQQYKLSLKELLILAYFY
                     YKNEHSISLKEIIGDILYKQSDVVKNIKSLSKKGFINKSRNEADERRIFVSVTPIQRK
                     KIACVINELDKIIKGFNKERDYI"
     gene            700..1051
                     /gene="sarT"
                     /locus_tag="RPH49_002236"
                     /pseudo
     CDS             700..1051
                     /gene="sarT"
                     /locus_tag="RPH49_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998869.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarT"
     gene            1356..3551
                     /locus_tag="RPH49_002237"
     CDS             1356..3551
                     /locus_tag="RPH49_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="E domain-containing protein"
                     /protein_id="HDY5125359.1"
                     /translation="MRDKKGPVNKRVDFLSNKLNKYSIRKFTVGTASILIGSLMYLGT
                     QQEAEAAENNIENPTTLKDNVQSKEVKIEEVTNKDTAPQGVEAKSEVISNKDTIEHEP
                     SVKAEDISKKEDTPKEVADVAEVQPKSSVTHNAETPKVRKARSVDEGSFDITRDSKNV
                     VESTPITIQGKEHFEGYGSVDIQSNPEDLKVSEVTRFNNKSIGKNELTGALQLKNKVS
                     FKNDFEFNIRVANNHQSVTTGADGWGFLFSKGDGNEYLQKGGILGPKGMENSAGFKID
                     TGYNFKDPMDKEEKQAGQGFKGYGTFVKTGADGTTAKVGTNIPTRGKADNSFQYADNS
                     IDTTDGKFHGQLLNNLKLAYNEKSGIMRAEYAGKIWEANISDLGLDKSEAYNFLITSS
                     QRQGTSQGVYANGWMRTDLNNSTFKLTPNLVNKTETKTVEIPFETKREFNPKLQPGEE
                     RVKQEGQPGSKTITTPITVNPLTGEKVGEGQPTEEITKQPVDKIVEFGGEKIPQGHKD
                     IFDPNLPTDQTEKVPGKPGIKNPDTGKVIEEPVDDVIKHGPKTGTPETKTVEIPFETK
                     REFNPKLQPGEERVKQEGQPGSKTITTPITVNPLTGEKVGEGQPTEEITKQPVDKIVE
                     FGGEKPKDPKGPENPEKPSRPTHPSGPVNPDNPGLSKDRAKPNEPVHSMDKNDKVKKS
                     KIAKKSVANQEKKRAELPKTGAESTQKGLIFSSIIGIAGLMLLARRRKN"
     gene            3934..5127
                     /locus_tag="RPH49_002238"
     CDS             3934..5127
                     /locus_tag="RPH49_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125360.1"
                     /translation="MLYLEVLKNRNFTYLLIGNFLRRSCFVLFSLQIIWFTVELTNQS
                     SLKLSMMVMSQTLPFIIFGIFGGAYSDKHNKKKILYLSDLILSLIIIIIPLLAITSNL
                     NYLTLLTISTAITIINCYTDPAFRAILPEIIDEEHLATSNALIDSLQRGSNIILPALI
                     GVIVILVGNVGVFFICSILLFLGFIFNALLKYTNNNMIDRHSKEDFSETWEFLKKSKE
                     IPFIIIIQFACILINTGLWRVALPLFISNILKEGVGVYGLATSCLGIASLLMSLIMGL
                     LSEKRLIFKFSIGVLVWGIGLSIINVFPSVAILYIGATLVGLGQSIEGLTRSVAIQIK
                     TPNHLMGKVFSISSTSNYAADTLSLGLISLIIPLLSLSNIFISGGAIISMLSLSGLKF
                     FKKSM"
     gene            5138..5341
                     /locus_tag="RPH49_002239"
     CDS             5138..5341
                     /locus_tag="RPH49_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125361.1"
                     /translation="MLINAIKVGIEMKYKISLAYNLAIIIGSLIILCILISRGYDIYV
                     ILIPILTILASLINLICDIKKHK"
     gene            complement(5449..5757)
                     /locus_tag="RPH49_002240"
     CDS             complement(5449..5757)
                     /locus_tag="RPH49_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125362.1"
                     /translation="MTVNIVFSIVFCISMVILGIYVAITKDFTLISYINQTTIADKHK
                     NQIAYIFTLCISLSAVFLMSSILCFEYDFIALSFLFLTIALLLIALFYVCFYKITKYP
                     "
     gene            complement(5901..6167)
                     /locus_tag="RPH49_002241"
     CDS             complement(5901..6167)
                     /locus_tag="RPH49_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125363.1"
                     /translation="MKGSKQILLIMGIISLIVLFIFTLFIMAQYAKHYEQKSDSSNAH
                     TLNSSSAIIEQHTMSNLASLDLYAPVRNITSSRDIHPIYFMTKD"
     gene            complement(6451..8259)
                     /locus_tag="RPH49_002242"
     CDS             complement(6451..8259)
                     /locus_tag="RPH49_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDY5125364.1"
                     /translation="MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSIHKCKGFSFHVL
                     LSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGK
                     FGLGEGRLNKFTIEKLALGLARYLNTQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQ
                     ITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASE
                     LASRYIEEVGDPLQIDIPSSKQNTSYIKPFPKSVTDGYMKHIQNMIGYIPKSDLQVVF
                     TSLHGTSVPIVPELLKSLNFNQFNLVEAQCKPDPNFSSVQSANPEDHRAFDKAVELAN
                     KSHANLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQ
                     SIVSSELTKSLSRYNNVEYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFV
                     RDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGFEGKKKI
                     NAIMTKFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSPKSNVIRVLFDEGF
                     IALRPSGTEPKIKLYVSLKCPNFDDVAQKINAMIFS"
     gene            8391..8783
                     /locus_tag="RPH49_002243"
     CDS             8391..8783
                     /locus_tag="RPH49_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(deoxy)nucleoside triphosphate
                     pyrophosphohydrolase"
                     /protein_id="HDY5125365.1"
                     /translation="MKKVINVVGAIIFSDNKILCAQRSEEMSLPLMWEFPGGKVEKNE
                     TEKDALIREIREEMKCDLIVGDKVITTEHEYDFGIVRLTTYKCTLNKELPTLTEHKSI
                     EWLSINELDKLNWAPADIPAVNKIMTEG"
     gene            8785..11646
                     /locus_tag="RPH49_002244"
     CDS             8785..11646
                     /locus_tag="RPH49_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3427 domain-containing protein"
                     /protein_id="HDY5125366.1"
                     /translation="MSRLLNDFNQSLHKGFIDKDISHKGNYTPKLLVNNKNEKVLSTI
                     IDELQKCETFYFSVAFITESGLASLKAQLLDLSNKGVKGKILTSNYLGFNSPKMYGEL
                     LKLKNVEVRLTDIAGFHAKGYIFEHKDYSSMVIGSSNLTSNALKVNYEHNVLLSTMKN
                     GDLVDSVKNEFDLLWQKSIPLTEQWINSYKESFEYRSLEKLAEVEQTQMLLADKVKKS
                     VEIVPNLMQAEALRSLKAIRDKAKDKALIISATGTGKTILCALDVREVNPNKFLFIVH
                     NEGILNRAKEEFKKVLPIKNDSDFGLLTGKHRDVDAKYLFATIQTLSRDDNFKQFDEN
                     EFDYIVFDEAHRSAASTYQRVFNYFKPKFMLGMTATPERSDELSIFELFDYNIAYEIR
                     LQAALESDILCPFHYFGVTDYVHQGIKEDDVTKLRYLTSDERVNYIIQKTDYYGYSGE
                     ILQGLIFVSSKKEAYDLADKLSSKGIKSVALTGDDSVNYRQIVIEKLKEGKINYIITV
                     DLFNEGIDIPEVNQVVMLRPTESSIIFIQQLGRGLRKSANKEYVTVIDFIGNYKTNYL
                     IPIALSGDQSQNKDNYKKFLTNNDSINGVSTINFEEVAKKQIYNSLDAVSLNQNKLIL
                     KAYEEVENRLGHMPLLMDFIQQHSIDPSVIFSKFSNYYEFLVRYKKIDTLLTENESKN
                     LVFFSRQIAPGLKRIDSLVLEELLKNELTYDELKNKMLNEVKVITEDDIDTSLRILDF
                     SFYNAGIEKIYGSPIIECNERMIRLSDAFTNALSNQTFKIFLEDLIELSKYNNEKYQK
                     GKNGLILYNKYSREDFSKIFNWNKNGSSVIMGYMIRSQEMPIFITYDKHEDISDSTKY
                     EDEFLSQDELKWFTKSNRTLKSKEVQKILSHRAKGIKMYIFVQKKDDDGIYFYYLGTA
                     GYIEGSEKQDKMPNGSNVVTMDLALDKAVRDDIYRYITN"
     gene            11952..12701
                     /locus_tag="RPH49_002245"
     CDS             11952..12701
                     /locus_tag="RPH49_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5125367.1"
                     /translation="MIHSKRLRLWLYLVLLAVFISACNVKEDKQIKENFNKTLSLYPT
                     KNLDDFYDKEGFRDQEFDKRDKGTWIINSGMNIQLKGGALKSREMVLYINRNTRTAKG
                     YFLISETTEDKKGYVHNKDKKYPVKMEHNQIIPTKPIRDDKLKKEIENFKFFVQYGDF
                     KDYKDGDISYNPNVPSYSANYQLNNDDYNVQQLRKRYDISTKRAPELKLRGSGDLKGS
                     SVGSKELEFNFIRNKEENVYFSDSINFKPTE"
     gene            12812..13597
                     /locus_tag="RPH49_002246"
     CDS             12812..13597
                     /locus_tag="RPH49_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5125368.1"
                     /translation="MMHSKKLMLGICLVLLIILIVGYVIMTKINSRSAQIKDTFNQTL
                     KLYPTKNLDDFYDKEGFRDQEFGKGDKGTWIINSGMNIQLKGGALKSREMVLYINRNT
                     RTTKGYFIVGEITKDKKGYTHDKDKKYPVKMEHNQIIPTKPIKDEKLKKEIEDFKFFV
                     QYGNFKDFKDYKNGDISYNPNVPSYSAKYQLSNDDYNVQQLRKRYDIPTKKAPELLLK
                     GDGDLKGSSIGSKDLEFIFVQNKRENIYFTDSVEFTPSEDDKS"
BASE COUNT         5232 a         1738 c         2330 g         4369 t
ORIGIN      
        1 ttatgtagtc tctttcctta ttaaatcctt taattatttt atctaactca ttaataacac
       61 aagcaatctt tttacgttgt attggagtaa ctgaaacaaa aatacggcgt tcatctgctt
      121 cgtttctaga cttatttata aatccttttt tagatagtga cttaatgttc tttacaacat
      181 cagattgttt gtaaagtatg tcaccaatga tttcttttag tgaaatactg tgttcatttt
      241 tgtaataaaa atatgctaat atcaacaatt cttttaatga taatttatat tgttgcttta
      301 actcttgagt gagaaaaaat atgtacgctt ctacatttat gaatttattg accttttcga
      361 aagtttgata gtccacctta cattctccta ctattttctg atgtcccaat actttatatt
      421 atttaaagta atataaaagc aatctctttt gaagacatgt taacctaaat atttttatat
      481 ataatatata taaaatgtaa ataactaaaa atcacggaat aacaaatgac aaattcattt
      541 attatccaaa aataaaaaca attgaacaaa atcaaaatat agtgttatga ttcatttgtg
      601 tttatagcta gcaccacaaa ctaaatatat ttggagttat tactagttaa agacaaatat
      661 tatttgacgt gacaattaaa agtaagggat gaagacttga tgaatgattt gaaaagcaag
      721 agcaatatta aattaatgaa aagagtatta actacatatg agctgcgtaa atatttaaaa
      781 aaatattttt gtcttacatt agataattat ttagtattag catatttaga tgtatttaaa
      841 aatgatgaaa tattttatga gagacattat aagttatatc ggtatagacc aatctagaat
      901 tgttaaaagc gtaaaagaat tatcaaaaaa gggttacttg aataaatgta gagacccaca
      961 tgatagtaga aatgtaatca ttgttgtttc tgtaaaacaa cacaattata ttaaaaatct
     1021 tttgagtgaa ataaatatta atgaaacata aagtatgttt cgagatttta atatcttggt
     1081 gcagttaaat gtatttttaa atgcgttaag gtatttttta ttttagaaat tcaatgctat
     1141 tgagttgatg ggtttttcca acagataaga atgaattatt cattgaaaac taaaaataat
     1201 aattttattt gtagattgtt ttaagtgttt caatatataa aataatttta taaagataag
     1261 tgttatattc cattgtgcaa ctcctattgt atttgtaaaa ttacatgtaa attcactgta
     1321 agtaaagtgg aaaatatgga aaaaggagta tgcaaatgag agataagaaa ggaccggtaa
     1381 ataaaagagt agattttcta tcaaataaat tgaataaata ttcaataaga aaatttacag
     1441 ttggaacagc atctatttta attggctcac taatgtattt gggaactcaa caagaggcag
     1501 aagcagctga aaacaatatt gagaatccaa ctacattaaa agataatgtc caatcaaaag
     1561 aagtgaagat tgaagaagta acaaacaaag acactgcacc acagggtgta gaagctaaat
     1621 ctgaagtaat ttcaaacaaa gacacaatcg aacatgaacc atcagtaaaa gctgaagata
     1681 tatcaaaaaa ggaggataca ccaaaagaag tagctgatgt tgctgaagtt cagccgaaat
     1741 cgtcagtcac tcataacgca gagacaccta aggttagaaa agctcgttct gttgatgaag
     1801 gctcttttga tattacaaga gattctaaaa atgtagttga atctacccca attacaattc
     1861 aaggtaaaga acattttgaa ggttacggaa gtgttgatat acaaagcaat ccagaggatc
     1921 taaaggtatc tgaagtcact cgtttcaata ataaaagtat tggaaaaaac gaattgacag
     1981 gagcattaca attaaagaat aaagtttctt ttaaaaatga ctttgagttt aacattagag
     2041 tagctaataa tcatcaatcg gtaacaactg gcgctgatgg atgggggttc ttatttagta
     2101 aaggtgacgg taacgaatat ttacaaaagg gaggtatatt aggtcccaaa ggaatggaaa
     2161 attcagcagg atttaaaatt gatacagggt ataattttaa agatcccatg gataaagaag
     2221 agaaacaggc aggacaagga tttaaagggt atggtacgtt tgtaaaaaca ggtgctgatg
     2281 gaactacagc aaaggttgga acaaacatac caacaagagg taaagcggat aattcattcc
     2341 aatatgcaga taattctatt gatacaacag atggaaaatt ccatggtcaa ttacttaata
     2401 atttaaaatt agcgtacaat gaaaaatcgg ggataatgag agccgaatat gctggtaaaa
     2461 tttgggaagc taatatatca gatttgggat tggataaatc tgaagcatat aactttttaa
     2521 ttacttctag tcaaagacag ggaacatctc aaggtgtata tgcaaatggt tggatgagaa
     2581 cagatttaaa taactcaaca tttaaactaa cgcctaatct agttaataaa acagaaacaa
     2641 aaacagtaga gataccgttc gagacaaaac gtgaatttaa tccgaagtta caacctggtg
     2701 aagagcgagt gaaacaagaa ggacaaccag gaagtaagac aatcacaaca ccaatcacag
     2761 tgaacccatt aacaggtgaa aaagttggtg agggtcaacc aacagaagag atcacaaaac
     2821 aaccagtaga taagattgta gagtttggtg gcgagaaaat accgcaaggt cataaagata
     2881 tcttcgatcc aaacttacca acagatcaaa cggaaaaagt accaggtaaa ccaggaatta
     2941 agaatccaga cacaggaaaa gtgatcgaag agccagtgga tgatgtgatt aaacacggac
     3001 caaaaacggg tacaccagaa acaaaaacag tagagatacc gtttgaaaca aaacgtgagt
     3061 ttaatccgaa gttacaacct ggtgaagagc gagtgaaaca agaaggacaa ccaggaagta
     3121 agacaatcac aacaccaatc acagtgaacc cattaacggg tgaaaaagtt ggcgaaggtc
     3181 aaccaacaga agagatcaca aaacaaccag tagataagat tgtagagttt ggtggcgaga
     3241 aaccaaaaga tccaaaagga cctgaaaacc cagagaagcc gagcagacca actcatccaa
     3301 gtggcccagt aaatcctgac aatccaggat tatcgaaaga cagagcaaaa ccaaatgaac
     3361 cagttcattc aatggataaa aatgataaag ttaaaaaatc taaaattgct aaaaaatcag
     3421 tagctaatca agagaaaaaa cgagcagaat taccaaaaac aggtgcagaa agcacacaaa
     3481 aaggattgat ctttagtagt ataattggaa ttgctggatt aatgttattg gcacgtagaa
     3541 gaaaaaatta aaataattca ttatttaaat aatacttgat ttgcattcac tatatttagt
     3601 ttgttaaaaa caacctagaa tatgatgaaa atgatataca ccccaaaagt tggattgaaa
     3661 gacctaactt taaggggtgt atttttgtta taaatttgat tttttgataa tattttcata
     3721 tttaatataa tcataattag tagaatataa cctctgagta gtcattttgg gggttatgta
     3781 tggtgtttca agtagtatgt aaatttcgaa ataattgata tttaactgac taaattatat
     3841 tagaattaat tgcgctttgg ataaagagag tttagaagaa ggtctaaaaa agctggtgga
     3901 tgcattcaat tatttttatg agaggtgata aatatgttgt acttagaagt tttgaaaaat
     3961 agaaacttta catatttatt gattggtaat ttcttacgtc ggagttgctt tgtgctgttt
     4021 tcgttacaaa taatttggtt tactgttgaa ttgacaaacc aatcatcttt aaaattatca
     4081 atgatggtta tgagtcaaac actaccattt attatatttg gtattttcgg tggcgcatat
     4141 tctgataaac ataataaaaa gaaaatactt tatctatctg atcttatact aagtttgatt
     4201 ataataatta ttcctttact tgcaataaca tcaaatttaa attatctgac gcttctaacc
     4261 atatctacag ctatcaccat tattaactgc tatacggatc ctgcgtttag ggcaattctt
     4321 cctgaaatta ttgatgagga gcatttagca acaagtaatg cgttaatcga tagtttgcaa
     4381 agaggctcaa atattatttt acctgcttta attggtgtca ttgtaatact agttggtaat
     4441 gttggcgtct tttttatttg cagtatattg ctatttttag gatttatttt taatgcactt
     4501 ttaaaatata caaataacaa catgattgat agacactcaa aagaagattt ttctgaaact
     4561 tgggaattct tgaaaaaatc taaagaaatt ccatttatta taatcattca atttgcctgc
     4621 atattgatta atactggcct ttggcgtgtt gcattaccat tgtttatttc caatatatta
     4681 aaagagggcg ttggtgtata tggactagct acatcatgtt taggtatagc gtctttatta
     4741 atgtcattga ttatgggttt actgtcagaa aaacgattaa tctttaaatt tagtattggt
     4801 gttttagttt ggggaattgg tttatcgatt attaatgtgt ttccaagtgt ggcgatattg
     4861 tatataggtg caacattagt gggacttgga caatctatag agggactaac aagatcagtt
     4921 gccattcaaa taaaaacgcc aaatcatttg atggggaaag tatttagtat ctcatctaca
     4981 tcgaattacg cagcggatac attatcttta ggactgataa gtttaattat acctttacta
     5041 agcttaagta atatatttat atcaggaggt gcaattattt caatgcttag cttatcgggg
     5101 ttaaagtttt ttaagaagtc tatgtaaaca taatagaatt ttaatcaatg ctattaaggt
     5161 gggaattgaa atgaaatata aaattagttt ggcttataat ttagcaatta taatagggtc
     5221 gctaattata ttatgtatac taatatctag aggttatgat atatatgtaa tcttgattcc
     5281 aattttgact attttagcta gtttaatcaa tttaatttgt gatattaaaa agcataaatg
     5341 attctatatt aatgcaactt tgtattcgta caaggttgta tttttttcgc aaacaattac
     5401 ttaatgacag cgcatcaata aatctaacca acacactatc gcaaacattt atggatattt
     5461 tgtgatttta taaaagcaaa cgtagaataa tgcgataagt aataatgcta tcgttaaaaa
     5521 taagaatgac aatgcaataa aatcatattc aaagcataga attgaagaca ttaaaaatac
     5581 tgcactcaaa ctgatacata gcgtaaatat atatgcaatt tggttcttgt gtttatctgc
     5641 aatggtcgtt tgatttatat aagaaattag tgtgaaatct ttagttattg cgacataaat
     5701 gcctaatata accatactta tgcagaatac gatactaaat acgatgttga cggtcattgt
     5761 tgcaccttcc tgatagaata taatgtactg tcttttagta atgaatgcgt atcttatata
     5821 tgtatgtttc taaaaaacag tacgttttta tcaattttta atttattagt tgaatgaatg
     5881 gggttatgaa aaaggaagtt ttaatctttt gtcatgaaat aaatgggatg aatatcacga
     5941 ctagaagtaa tgttacgaac aggagcgtat aaatctagag acgctaaatt cgacatagta
     6001 tgttgctcaa ttatggctga tgatgagttt aaagtatgtg cgttggaact gtcggatttt
     6061 tgttcataat gttttgcata ttgtgccatg atgaatagtg taaaaataaa taaaacaata
     6121 agagatataa tgcccataat caaaagtatt tgtttagagc ctttcattat ttcacatcct
     6181 ttctaaaata tatttgtaac taaatttaaa atagttattt ttgtaattct aaaccttttt
     6241 catcgcgaaa acaattaaat aggtcgcggt attaattatt atattattac cgcttaatat
     6301 gaaaaataca tgaaaattaa ttttctaata tacttttgaa aaattattac aaattagccc
     6361 cttcaaaacg cgaaaacata aggattctag tttcaaaagg gctgataagt ataaaatgaa
     6421 atgtaatatt tcgatgttta aaatttttaa ttagctaaaa atcatcgcat taattttttg
     6481 agctacatca tcaaaattcg gacattttaa cgacacatat aatttaattt taggttcagt
     6541 accagaagga cgtaaagcga taaatccttc gtcaaataag acacgaataa catttgattt
     6601 aggagaatta atctgcgacg ttgtgtcttt atccaaatga taaacctcgc tagttaaata
     6661 atcttcaatt gctttcactt tcagtccttg aatctcttgc ggtggatttg aacggaattt
     6721 ggtcattatt gcattaattt tctttttccc ttcaaatcct tctagcgtat gcgagaataa
     6781 tgtatcctca tgtctaccaa cagtttgata aatctgttct aattcatctt tcaatgtttt
     6841 gccatataat tttaactcag aagcgtattt tataatgagt ggcacaattt gtacggcatc
     6901 tttatcacgt acaaaaggct ctgatagaaa accgtaactc tcttcaaatg cgaaaatcat
     6961 attttgatga tcatccagtt gtcttatttc ctgagcaata aatttaaagc ccgtcagcac
     7021 ctctttgtat tcaacattat tatagcgtga taatgacttt gttaactcac tacttacaat
     7081 agattgaatc attaagcggt gacgtaattg agacgtttgt tgaatacgat aattaagtaa
     7141 cagcgcacca atttggttgc cattaaaata cgtgatatga ccatgtgcat cacgttcagc
     7201 aatgccaaga cgatccgcat caggatcagt tgatattaat aagtttgcat gacttttatt
     7261 tgcaagttcg actgctttat caaaagcgcg atgatcttca ggattagcac tttgaactga
     7321 gctaaaattc ggatcaggtt tacattgtgc ttctacaaga ttaaattgat tgaaattcaa
     7381 agattttaat aactcaggta caatcggaac acttgtacca tgtaaactag tgaacacaac
     7441 ttgtaaatca gatttaggaa tatagccaat catattttga atgtgtttca tatagccatc
     7501 agttacagat ttcggaaatg gcttgatata agatgtattt tgttttgaag aaggtatgtc
     7561 aatctgtaat ggatcgccaa cttcttcgat ataacgactt gcaagctcag atgcatctgt
     7621 tgatagttgc gcaccatcag aaccatatac tttaatgccg ttatagtctt tcggattatg
     7681 acttgctgta atcataatgc cagcagtagt attaagattg cgcaccgcga acgataattc
     7741 cggtgtcgtt ttatatgtat caggtaaata aactgttatt tgatggtttg ctaatacatt
     7801 agcaataatt tgggcgaatt cagttgaaag atgtctaata tcataatgaa tgactattgt
     7861 tggactgttt gtttgggtat ttaaataacg cgctaaacct aatgccaatt tttcaatagt
     7921 aaacttatta agtcgacctt caccaagacc gaattttccg cgtatacccg cagtaccaaa
     7981 tgttaattta ctttcaaaac cttctcgctg ttcaatgtca gattgctgct cataaaaatg
     8041 tttaactaaa ctatcattag ctctttctat ccataattct ttatccattg ttgctaaaca
     8101 tcctttcaaa atctcagtta gacttaataa aacatgaaaa ctaaagccct tacatttatg
     8161 tattgaatta taaagaaata cgccccaaaa gtaaaaaaac acagccccaa gacaatactt
     8221 ttcacaagta ttatataata gatgtgtatg aaaatgcatg gagtagatgt aagagtgata
     8281 tatcatgcag gaaaatgtaa aatattaatt tttaatattg atttatatat agttttgtaa
     8341 tttttgatag aataacaatt aagatgattt taaattgaag ggtgagtctt atgaaaaaag
     8401 taatcaatgt agtaggagct attatttttt ctgataacaa aattctttgt gcacagagaa
     8461 gtgaagaaat gagtctgcct ttaatgtggg aatttcctgg aggtaaggtt gaaaagaatg
     8521 aaactgaaaa agacgctttg attagagaaa ttagagaaga aatgaaatgt gatctaattg
     8581 ttggagacaa agttataact acagaacatg aatatgattt tggaattgtt aggttaacaa
     8641 catacaaatg tactttaaac aaagagttac caactctaac tgaacataag agtattgaat
     8701 ggttgtcaat aaacgaactt gataaattaa attgggcccc agcggatata ccagccgtta
     8761 ataaaattat gaccgaggga taatatgagt agattactaa atgatttcaa tcaatcttta
     8821 cataaagggt ttatagacaa agatatttct cataaaggta attatacacc gaagctttta
     8881 gtaaataata aaaatgaaaa agttctttca acaattatag atgaacttca aaaatgtgaa
     8941 acgttctatt tttctgtagc ttttataaca gaaagcggtt tagccagctt aaaggctcaa
     9001 ctattagatt taagcaataa gggtgttaaa gggaaaatat taacatctaa ttacttaggg
     9061 tttaatagtc ctaaaatgta tggagaatta cttaaattaa aaaatgtaga ggtaagatta
     9121 accgatattg ctggattcca tgccaaagga tatatttttg aacataagga ttatagttct
     9181 atggtaatag gaagctctaa tttaacatct aatgcgttaa aggttaatta tgagcataat
     9241 gttttactgt ctactatgaa aaatggcgat ttagttgata gtgtaaaaaa tgaatttgac
     9301 ttgttatggc aaaagagtat cccactgact gagcaatgga ttaattcata taaagaatca
     9361 tttgagtacc gttccttaga aaaattagcg gaggttgaac aaactcaaat gctgctagct
     9421 gataaggtga aaaaatcagt ggaaattgta cccaatttaa tgcaagcaga agcattaagg
     9481 tcattaaaag ctattaggga taaagccaaa gataaggcgt taataatatc tgcaactggt
     9541 acaggtaaaa cgattttatg tgcattagat gttagagaag taaaccctaa taaattttta
     9601 tttattgttc ataatgaggg gattttaaat agagctaagg aagaatttaa aaaagtatta
     9661 cctataaaaa atgatagtga ttttggattg ttgacaggaa aacatagaga tgtcgatgcc
     9721 aaatatttat ttgcaaccat tcaaacatta tctagagatg ataattttaa gcaatttgat
     9781 gaaaatgaat ttgattatat tgtttttgat gaagcacatc gttctgctgc atctacttat
     9841 caacgagtat ttaattactt caaacctaag ttcatgctgg gaatgactgc tacaccagaa
     9901 agatcagatg aattaagtat atttgaactg tttgattata atattgcata tgaaataagg
     9961 ttacaagcag cgttagaaag tgatatttta tgtccatttc attattttgg tgtgactgat
    10021 tatgtacatc aaggtattaa agaagatgat gtaactaaac tgagatattt aacttctgat
    10081 gaaagagtta attatattat tcaaaagaca gattactatg gatattcagg tgaaatttta
    10141 caaggattaa tttttgtgag tagcaaaaaa gaagcttatg atttagcgga taaactaagt
    10201 tcaaaaggga ttaaaagtgt tgctttaaca ggagatgata gtgttaatta tcgccaaatt
    10261 gtaatagaaa aattaaaaga aggtaagatt aactatatta taactgtaga tctttttaac
    10321 gaaggtattg atattccaga agtcaatcaa gttgtaatgt tgagaccaac agagtctagt
    10381 attatattca ttcagcaact tggtagagga ttaagaaaaa gtgcaaataa agagtatgtt
    10441 actgtaattg attttattgg taattataag accaattatt taattccgat tgcgctttct
    10501 ggagatcaat cgcaaaataa agataattat aagaagtttt taacgaataa cgattcgatt
    10561 aatggagtat ctacaattaa ttttgaagaa gttgctaaaa aacagattta caattcattg
    10621 gatgcagtat cattgaatca aaataaatta atattaaaag cttatgaaga agttgaaaat
    10681 agattgggac acatgccgtt actaatggat tttatacaac aacattctat agatccaagc
    10741 gttatatttt ctaaatttag taattattac gagtttttag taaggtataa aaaaatagat
    10801 actttattga cggaaaatga atctaaaaat ctggttttct tttcaagaca aatagcacct
    10861 ggattgaaaa gaatcgatag tttagtttta gaagaacttt taaaaaatga attaacatat
    10921 gatgaattaa aaaataaaat gttgaacgaa gttaaggtta taacagaaga tgatatagat
    10981 acttcattaa gaattttaga tttttcattt tacaacgcag gaattgaaaa aatctatgga
    11041 agtcccatta tagaatgtaa tgaaagaatg ataagactaa gcgatgcatt tactaatgct
    11101 ctaagtaatc aaacatttaa aatattttta gaagatctta ttgaattatc aaagtataac
    11161 aatgaaaaat accaaaaagg taaaaatgga ctgattttat ataataaata ttcaagagaa
    11221 gattttagca aaatatttaa ttggaataaa aatggttcgt ctgtaatcat gggatacatg
    11281 ataagaagcc aagaaatgcc aatatttatc acttatgata agcatgagga tataagtgat
    11341 agcacaaaat atgaagatga atttttaagt caagatgaat taaaatggtt tactaaatct
    11401 aatagaacgc taaaatcaaa agaagttcag aaaattttgt cccatagagc aaaaggaatt
    11461 aaaatgtata tttttgtaca gaaaaaagat gatgatggta tatattttta ttatttagga
    11521 actgctggat atatagaagg ttcagagaag caagataaaa tgccgaatgg ttcaaacgta
    11581 gtaactatgg atttagcact cgataaagct gtaagagatg atatatatcg ctatataaca
    11641 aattaatgta aaccgaaaaa tgaatgttag taaagatgta tttaaacatc acttttaata
    11701 agtaaagaca ttgagtttca gtgttattat tttaaatata agcgcaattt atcttaatta
    11761 attagttggt taggccaata aaaattataa agatatttgc gctttttaaa taatttgtga
    11821 tgttgatatg tgaaaaatac aactaacaat taaaagccaa gaggatttaa tcataaaatt
    11881 ccctctagta ttattaatat tggaatttga acttaacttt gcatcaaaaa taaaaatggg
    11941 ggtgtgaaat gatgattcat tcaaaaaggt tgaggctctg gctgtattta gtattattag
    12001 ctgtttttat tagcgcgtgt aacgtgaaag aagataaaca aattaaagaa aatttcaaca
    12061 aaacattgag tttatatcca accaagaatc tcgatgattt ttacgataag gaaggttttc
    12121 gagatcaaga gtttgataaa agagataaag ggacttggat tattaattct ggaatgaaca
    12181 tccaattaaa aggaggagct ttaaaatcca gagagatggt actttacatc aatcgtaaca
    12241 ctagaacagc taagggatat tttttaataa gtgagacaac agaagacaaa aaaggatacg
    12301 tccataataa agataaaaaa taccctgtca agatggaaca taatcaaatt attccaacga
    12361 agcccataag ggatgataag ttaaaaaaag agattgaaaa ctttaagttc tttgtacaat
    12421 atggggattt taaagattat aaagatgggg atatttcata caatcctaac gtaccaagtt
    12481 attccgcaaa ctatcaattg aataatgatg attataatgt ccaacaatta agaaaacgat
    12541 atgatatatc aaccaaaagg gctccggaat taaaattgag aggatctggc gatttaaaag
    12601 gctcatctgt aggttctaaa gaactagaat ttaactttat aagaaataaa gaagaaaatg
    12661 tgtatttttc tgatagtatt aatttcaaac ctactgaata gggttaatag aagtttggaa
    12721 taaaattcca taaagtgttc aaaataattt ttcgctttag ttgtaaatat taaaaactga
    12781 gtcagtatta aaaatataag gtggagaaat gatgatgcat tcaaagaaat taatgctcgg
    12841 tatatgtttg gtattactca ttatattgat tgtaggttat gtcattatga caaaaataaa
    12901 tagtcgaagc gcccaaatta aagacacatt taatcaaaca ttaaaattat atccaaccaa
    12961 aaatctcgat gatttttacg ataaggaagg ctttcgagat caagaatttg gcaaaggaga
    13021 caaaggtact tggattatta attctggaat gaacatccaa ttaaaaggag gagccttaaa
    13081 atccagagag atggtacttt acatcaatcg taacactaga acaacgaaag gatattttat
    13141 agtaggtgag ataactaaag ataaaaaagg atatacacat gataaagata aaaaataccc
    13201 tgtcaagatg gaacataatc aaataatccc aacaaaacct ataaaagacg agaagttaaa
    13261 aaaagaaatt gaagacttta agttttttgt acaatatggc aactttaaag attttaaaga
    13321 ttataaaaat ggggatattt catacaatcc aaacgtacca agttattcgg caaaatatca
    13381 attaagtaat gacgattata atgtccaaca attaagaaaa agatatgata taccgactaa
    13441 aaaagcacca gaactattgt tgaaaggtga tggcgattta aaaggttcat ccataggctc
    13501 taaagactta gaatttatct ttgtacaaaa taaaagagag aatatctatt ttacagattc
    13561 ggttgaattt actccaagcg aggatgataa atcgtgagtc aaactgaata gggataatag
    13621 aagtttggaa ttaaattttc ataaagcact aggtaaaaga ttataacga
//
LOCUS       DAPSKH010000066        13610 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPSKH010000066 DAPSKH010000000
VERSION     DAPSKH010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13610)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13610)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13610
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.066"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(159..731)
                     /gene="raiA"
                     /locus_tag="RPH49_002247"
     CDS             complement(159..731)
                     /gene="raiA"
                     /locus_tag="RPH49_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDY5125369.1"
                     /translation="MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKV
                     KTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRD
                     RGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDF
                     FVFTDRETDGTSIVYRRKDGKYGLIQTSEQ"
     gene            complement(792..1466)
                     /locus_tag="RPH49_002248"
     CDS             complement(792..1466)
                     /locus_tag="RPH49_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDY5125370.1"
                     /translation="MNNCLSCGAKLYENITIYNLFKKPNRLCDRCKENWDNIKLDIKA
                     RRCSRCLKYLNQNEAYCLDCKFLSAHFNLMEQLYCQFQYDGLMKEMIHQYKFLKDYYL
                     CELLAHLIEIPQTSYDYIVPIPSSPAHDLSRTFNPVEAVLKAKGIRFDKILKMSNRPK
                     QSHLTKKERLADENPFIIDTELDLNGKEILLVDDIYTTGLTIHRAGCKLYAKNIRKFK
                     VFAFAR"
     gene            complement(1459..2541)
                     /locus_tag="RPH49_002249"
                     /pseudo
     CDS             complement(1459..2541)
                     /locus_tag="RPH49_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011382223.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
     gene            complement(2905..3771)
                     /gene="fakB1"
                     /locus_tag="RPH49_002250"
     CDS             complement(2905..3771)
                     /gene="fakB1"
                     /locus_tag="RPH49_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase binding subunit FakB1"
                     /protein_id="HDY5125371.1"
                     /translation="MKIAVMTDSTSYLSQDLIDKYNIQIAPLSVTFDDGKNFTESNEI
                     AIEEFYNKMASSQTIPTTSQPAIGEWITKYEMLRDQGYTDIIVICLSSGISGSYQSSY
                     QAGEMVEGVNVHAFDSKLAAMIEGCYVLRAIEMVEEGYEPQQIIDDLTNMREHTGAYL
                     IVDDLKNLQKSGRITGAQAWVGTLLKMKPVLKFEDGKIIPEEKVRTKKRAIQTLEKKV
                     LDIVKDFEEVTLFVINGDHFEDGQALYKKLQEDCPSGYQVAYSEFGPVVAAHLGSGGL
                     GLGYVGRKIRLT"
     gene            3915..4556
                     /locus_tag="RPH49_002251"
     CDS             3915..4556
                     /locus_tag="RPH49_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDY5125372.1"
                     /translation="MTQNIITVKKEHIIENVISKSKFIAHIKPVQNEDEAKAFIAAIK
                     KEHKDATHNCSAYTIGPEMNIQKANDDGEPTGTAGVPMLDILKKLDVHNACVVVTRYF
                     GGIKLGGGGLIRAYSGAVRDVIYDVGRVELREAVPCIVTLNYDQTGKFEYELASTHFM
                     LRNQTYTDKVSYYIDVVKSDYEAFINFLNQMTAGNFDLTEETPKQLPFDIPTE"
     gene            complement(4720..5775)
                     /locus_tag="RPH49_002252"
     CDS             complement(4720..5775)
                     /locus_tag="RPH49_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDY5125373.1"
                     /translation="MVTLLLVAVTMIVSLTITPIVIAISKRLNLVDKPNFRKVHTKPI
                     SVMGGTVILFSFLIGIWIGHPIETEIKPLIIGAIIMYVLGLVDDIYDLKPYIKLAGQI
                     AAALVVAFYGVTIDFISLPMGTTIHFGFLSIPITVIWIVAITNAINLIDGLDGLASGV
                     SAIGLITIGFIAILQANIFITMICCVLLGSLIGFLFYNFHPAKIFLGDSGALMIGFII
                     GFLSLLGFKNITIIALFFPIVILAVPFIDTLFAMIRRVKKGQHIMQADKSHLHHKLLA
                     LGYTHRQTVLLIYSISILFSLSSIILYVSPPLGVVLMFILIIFSIELIVEFTGLIDNN
                     YRPILNLISRKSSHKED"
     gene            6093..7163
                     /locus_tag="RPH49_002253"
     CDS             6093..7163
                     /locus_tag="RPH49_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDY5125374.1"
                     /translation="MFEAFIYNISVIVAGIYLFHRLQYSENKRMVFSKAYVTVLMTIV
                     SLLLSVYPIPYREDYLIHLTFVPLLFLGRFTNMVYTLSATVIVAIVEIVVFNNSIMYG
                     VTLIVIAAVTSAIGPFLKQNDVLSLLILNVVTIIILFGVALVSPIYTLSEVIILIPIS
                     LIITLASAITFVDIWHFFSLVNRYENEDKYDYLTGLGNVKEFDRHLNEISRKAEKEHQ
                     SIALLLIDIDGFKDVNDTYSHKSGDAVLKQMSQLLKNYVPNQFKIFRNGGEEFSVVIH
                     NYSLDQSVKLAENIRSGVEKSSFHLPNKEVIKLSVSIGVGYLTDDDPKSQRKVFKDAD
                     DMVHVAKNQGRNKVMFNPIINL"
     gene            7359..8120
                     /locus_tag="RPH49_002254"
     CDS             7359..8120
                     /locus_tag="RPH49_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDY5125375.1"
                     /translation="MPDSITIIDENKVIDVVLIAGRILLESGAETYRVEDTMNRIAHS
                     YGLHNTYSFVSSTAIIFSLNDRTSTRLIRVQERTTDLEKIALTNSLSRKISNKELTID
                     EAKSEFIHLQHASLQYSFLTNFFAAAIACGFFLFMFGGVASDCWIAVIAGGSAFLTFS
                     FVQRYIQIKFFSEFVAAAVVISIAATFTKLGIATNQDIITIASVMPLVPGILITNAIR
                     DLLAGELLAGMSRGVEAALTAFAIGAGVAIVLLII"
     gene            8138..8632
                     /locus_tag="RPH49_002255"
     CDS             8138..8632
                     /locus_tag="RPH49_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDY5125376.1"
                     /translation="MLFYLFHFTISFISTVLFSIIFNAPKRLLVACGFVGAIAWTIYQ
                     LTVDLEFGKVGASFLGSLILGLMSHTMSRRYKRPVIIFIVPGIIPLVPGGAAYQATRF
                     LVSNDYTSAVNTFLEVTLISGAIAFGILVSEILYYLYTRIKQLYGKIKGKTYKKSYNM
                     NNRV"
     gene            8646..9872
                     /gene="pepT"
                     /locus_tag="RPH49_002256"
     CDS             8646..9872
                     /gene="pepT"
                     /locus_tag="RPH49_002256"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDY5125377.1"
                     /translation="MKNQLIDRLTRYTTIDTQSDPKSTTTPSTEKQWDLLHLLEKELQ
                     QLGLPTDLDENGYLFATLESNIDVDVPTVGFLAHVDTSPDFNASNVKLQIIENYDGKP
                     YKLGNTKRVLDPKVFPELNSLVGHTLMVTDGTSLLGADDKAGIVEIMEAICYLQEHPE
                     IKHGTIRIGFTPDEEIGRGPHKFDVDRFNADFAYTMDGSQYGELQYESFNAAEAIITC
                     HGVNVHPGSAKNAMVNAIRLGEQFDSLLPDSEVPERTEGYEGFYHLMNFEGTVEKATL
                     QYIIRDHDKKQFELRKKRILEIRDDINAHFENYPVKVDISDQYFNMAKKILPLPHIID
                     IPKRVFAKLDIPANTEPIRGGTDGSQLSFMGLPTPNIFTGCGNFHGPYEYASIDVMEK
                     AVQVIIGIVEDIAENH"
     gene            complement(10060..11184)
                     /locus_tag="RPH49_002257"
     CDS             complement(10060..11184)
                     /locus_tag="RPH49_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDY5125378.1"
                     /translation="MKVLVAMDEFHGIISSYQANRYVEEAVASQIETADVVQVPLFNG
                     RHELLDSVFLWQSGQKYRIPVHDADMNEVEGVYGQTDTGMTVIEGNLFLKGKKPIVER
                     TSYGLGEMIKHALDNDAKHVVISLGGIDSFDAGAGMLQALGAQFYDDEGRVVDMRQGA
                     GVIKYIRRMDMSNLHPKMETARIQVMSDFSSRLYGKQSEIMQTYDAHQLNHNQAAEID
                     NLIWYFSELFKSELKIAIGPVERGGAGGGIAAVLNGLYQAEILTSHALVDQLTHLENL
                     VEQADLIIFGEGLNENDQLLETTTLRIAELCHKHQKVAIAICATAEKFDLFESQGVTA
                     MFNTFIDMPESYTDFKMGLQIRHYTVQSLKLLKTHFNVEV"
     gene            complement(11609..11929)
                     /gene="ytxJ"
                     /locus_tag="RPH49_002258"
     CDS             complement(11609..11929)
                     /gene="ytxJ"
                     /locus_tag="RPH49_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol system redox-active protein YtxJ"
                     /protein_id="HDY5125379.1"
                     /translation="MAIKLSSIDQFEQVIEENKYVFVLKHSETCPISANAYDQFNKFL
                     YERDMDGYYLIVQQERDLSDYIAKKTNVKHESPQAFYFVNGEMVWNRDHGDINVSSLA
                     QAEE"
     gene            complement(12083..12961)
                     /locus_tag="RPH49_002259"
     CDS             complement(12083..12961)
                     /locus_tag="RPH49_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EMYY motif lipoprotein"
                     /protein_id="HDY5125380.1"
                     /translation="MKKIVIIAVLAILFVVISACGNKEKEAQHQFTKQFKDVEQKQKE
                     LQHVMDNIHLKEIDHLSKTDTTDKNSKEFKALQEDVKNHLIPKFEAYYKSAKNLPDDT
                     MKVKKLKKEYMTLANEKKDAIYQLKKFIGLCNQSIKYNEDILDYTKQFEKNRYKVESE
                     IKLADNKSEATNLTTKLEHNNKALRDTAKKNLDDSKENEVKGAIKNHIMPMIEKQITD
                     INQTNISDKHVNNARKNAIEMYYSLQNYYNTRIETIKVSEKLSKVDVDKLPKKGIDIT
                     HGDKAFEKKLEKLEEK"
     gene            13081..13599
                     /locus_tag="RPH49_002260"
     CDS             13081..13599
                     /locus_tag="RPH49_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GrpB family protein"
                     /protein_id="HDY5125381.1"
                     /translation="MYSNVQPFINSDLTNCFQSQYTEIESLLFNLLDSPVKYTKHIGG
                     THHFKYSTEPILDILVGVENLHDITSLDEKRLNYVGFYRLHHKYNKKVMMAKFNNFHE
                     LKQQVRLHIIQMNTQTFESYLALDYLLSTNDEIALQFNTKKHQILQHSFTIRQYEMQK
                     QKYFEKLCKKYL"
BASE COUNT         4490 a         2336 c         1939 g         4845 t
ORIGIN      
        1 ttattaactt aacattcaaa tatatacatc cattaacatt agcatagtca ctatgtttca
       61 ttcaacaaat tgcacaaacg aactgtgaaa tagttagaaa ttgcttttga agtctaaaaa
      121 aagcacttgt gcaaaaacac aagtgcttta aacttaattt attgttcact agtttgaatc
      181 aagccatatt taccgtcttt acggcggtaa acgatacttg ttccatcagt ttctctgtct
      241 gtgaatacaa agaaatcatg acctaataga ttcatttgta ataccgcttc ttctgaatcc
      301 attggtttta agctgaattc ttttgaacga ataatttcta tctcgttatc atcgtaagcg
      361 tcattatcaa cttgtgtttc ttgcatttct tgtaattcgg caacaaacac ttcttgatct
      421 cctcgatcac ggctcttacg attaatacgt gttttatatt ttcgaacttg tctttcaagt
      481 ttattattaa ttaaatcaat acctgcgtat aaatcatcgt ttcgctcttc agctcttaac
      541 gtaacatttt tcaatggaat tgttacttca attttagtag ctgaatttga ataagtttta
      601 actttaacat gcgccactgc atttggtacg tcattaaaat aacgttccaa cttaccaatt
      661 ttttcctcaa tatagttgcg aatagcatct gtgatagtga ggttatctcc atgaatttca
      721 aatctaatca tagtaatctc tccttaaacc tctttattgg taactcttta ttatatttta
      781 acatttttac gctatcgtgc aaacgcaaac actttgaatt ttctgatatt tttagcatat
      841 aatttacacc ctgcacgatg aattgttaat ccagttgtat aaatatcgtc aacgagtaat
      901 atttccttgc cgttcaaatc taattccgta tcaataataa atggattttc atctgccaga
      961 cgctctttct tagttaaatg agactgtttt ggtctatttg acatctttaa aatcttatca
     1021 aagcgaatcc ctttagcttt tagtactgct tctaccgggt taaatgttct agataaatca
     1081 tgtgccggcg aagaaggaat tggcacaata tagtcataag atgtttgtgg tatttcaatc
     1141 aaatgtgcca ataattcaca taaataatag tctttcaaaa atttatactg atgtatcatc
     1201 tctttcatta aaccatcata ttgaaattga caatataatt gttccattaa attaaagtgt
     1261 gccgatagaa acttgcagtc taaacaatac gcttcatttt gatttaagta ttttaagcat
     1321 cttgaacatc gccttgcttt aatatcaagt ttaatattgt cccaattctc tttgcatctg
     1381 tcacataatc tattaggttt cttgaacaaa ttataaatgg ttatattttc atataactta
     1441 gcaccacaac tcaaacaatt attcatcaat ccaacctctt tttaatgcta atttgttcat
     1501 cttttgaatc tcttttttag cttgaatcat attcatactt actccttcat gaaaaaacaa
     1561 tacttttcca gtaggacatt ctaattttcg tccaacacgt ccagcaattt gtattaaagc
     1621 ctcttgagta tattgatgcg catcgataac aaccacatcc aaatttgcca ttgtaaatcc
     1681 acgttctaat attgtcgtag taaaaatgac atcaaattgt ccattcctta attattcaac
     1741 tttttcaaag cgaaaaacat cctcgctatg gacatatgtt aatttagtaa ttttctgctt
     1801 ataaaccgaa aatgttttaa tcattgtttc tatattgtta aaaaacacca gtgtataacg
     1861 ttgtttatta atttgatctt gtaaaattcg atataacatt ttctgaatct tattattatt
     1921 gagtttgaaa tagcgatatt taggaactgg aagtgatttt ttatgaaagc gagctggcaa
     1981 tttaattaca ttttcgtggg gaatctctga cagaagttgt ttcggtggtg ttgctgtcat
     2041 ataaattgtt gcatgttcaa ctttagaaga tgacttcaat gcttgttgta aacttttatc
     2101 cattgataaa ggaaaggcat cgacttcatc aataaaaata gtatcaaagt gctgtttgaa
     2161 tcggtaaagt tgatgcactg tgcatacaac aaaatgccct tcaaattgtt gacttgattg
     2221 ctggtgtagt atgtctatat cttcattaag aaatgcgtct ttaatacgtt tactaatttc
     2281 tacaacaaca tctacacgtg gtgacacaat agctatatta tctccctgtc gtcttgcata
     2341 ttgaatgcct tgaaacatca tttctgtctt acctgcacct gttactgcat ataacaaaat
     2401 cgtttgtctc attctaatgg ctcgaacaat atgttctgag gcataagact gctgttccga
     2461 caattcaaat gagagatgat aataggcttg tgatgaactt tgcgaactct ctgttatttt
     2521 atatcttgtt acattatcca ttcgacccag tgatatacaa tttctgcaat atacaatttt
     2581 tttggaatgt actgaggaat catactgata aaaatgcttt ggatttgtac tttcacattg
     2641 aacacaataa tagtttgaat tttgtttgat gacacctgtt acttcttttt taattttttc
     2701 attagtaagt gaagtatgag gatgaattaa tttcccgtaa tgtttaatgc ttaaaacctc
     2761 atttcaacgt aaaaaagagt ctaatattat aatgattttc ttatatcttt agcattttga
     2821 cattcaaatg atgaacattt aaagccatgt atgcaagaga taatttccaa ttacaatata
     2881 gactctttta ttaaaatttt ataattatgt taatcttatt tttctgccaa catagcctaa
     2941 acctaatcca ccagaaccta aatgtgctgc aacaactgga ccaaactcag agtatgctac
     3001 ttgataacct gaaggacaat cttcttgtaa ctttttgtat aacgcttgac catcttcaaa
     3061 atgatctcca tttatgacaa ataaagttac ttcttcaaag tcttttacaa tgtctaacac
     3121 tttcttttct aatgtttgaa tggcacgctt tttagtacga actttttctt ctggtataat
     3181 cttgccatct tcaaacttaa gaactggctt catttttaat aatgttccaa cccatgcttg
     3241 agcaccagta attcgaccac ttttttgtaa attctttaag tcatcaacaa ttaaatatgc
     3301 accagtgtgt tcacgcatat tagttaaatc atcaataatt tgctgtggtt cgtatccttc
     3361 ttcaaccatt tcaatagcac gtaatacata acaaccttca atcattgctg caagcttact
     3421 atcaaatgca tgtacattaa caccttcaac catttcccct gcttgataac tagattgata
     3481 acttccacta attccacttg ataagcaaat gacaatgata tctgtgtaac cttgatctct
     3541 tagcatttca tatttagtaa tccattcgcc aattgctggt tggcttgttg ttggaatcgt
     3601 ttgagacgat gccattttat tataaaattc ttcaattgct atttcattac tttctgtaaa
     3661 gttcttccca tcatcaaaag tcacacttaa tggcgctatt tgaatattat atttatcgat
     3721 taagtcctgc gacagataac ttgtagaatc ggtcatcaca gcaattttca tagtcgtcct
     3781 cctaaaatat actcatagca atgatacaat atttcagtta aaaagaaaat ggcaatcaaa
     3841 cgatttatag tcatgtcatt ttcagtgtat aatgaagatt aaataatctt aagcttatga
     3901 attaaggagt tattatgaca caaaatatca ttactgttaa aaaagaacac attattgaaa
     3961 atgtgattag taaatcaaaa ttcattgctc atatcaaacc tgttcaaaat gaagatgaag
     4021 ctaaagcatt tattgctgca ataaaaaaag aacataaaga tgccactcat aattgttctg
     4081 catatactat tggacctgaa atgaatattc aaaaagcgaa tgatgatggt gaaccgacag
     4141 gaactgccgg tgtcccaatg ttagacatat taaaaaagct cgatgttcat aatgcgtgtg
     4201 tcgtagtaac aagatatttt ggtggtatta aattaggtgg cggcggttta attcgcgcct
     4261 atagcggtgc tgttagagac gtcatttatg atgtcggacg tgtcgaacta cgagaagcag
     4321 taccatgtat agtaacactg aattatgatc aaactggtaa atttgaatat gaattagctt
     4381 caactcattt tatgttaaga aaccaaacat acactgataa ggtaagctac tatatcgatg
     4441 tcgttaaaag tgactatgaa gcgtttatta actttttaaa tcaaatgact gctggaaatt
     4501 tcgatttgac tgaagaaact ccaaagcagt tacctttcga tataccaact gaataaaaat
     4561 aaaaacacta gcttaggatg gctaactcta attgcgtatt gttactttgc aattttgaaa
     4621 gcacgttcca tgctagtgtt ttttgtgagt atgccttcct ttataacaac ataaaagtac
     4681 agacatcatt ttttatttta ttacttaccg ttttaaaatc taatcttctt tgtgtgacga
     4741 tttccgacta attaaattta atattggtcg gtagttgtta tctattaatc ctgtaaattc
     4801 aacaattaat tcaatgctaa atatgattaa tataaacatt aatacaacac ctaatggtgg
     4861 cgatacatac aagataatgc tcgaaagact aaataaaata gagattgaat agattaataa
     4921 tactgtttgt ctatgtgtgt agcctaatgc taatagttta tgatgcaaat gcgatttatc
     4981 agcttgcatt atatgctgcc cttttttcac acgtcgaatc attgcgaaca aagtatcaat
     5041 gaatggcact gctaggataa caattgggaa gaacaatgca ataattgtaa tatttttgaa
     5101 tccgagcaaa gaaaggaatc cgatgataaa tccaatcatt aaagccccac tatcacctaa
     5161 aaatattttg gcaggatgga aattgtaaaa taaaaaccca attaaagagc ctaataaaac
     5221 acaacaaatc atcgttatga aaatattagc ttgtaaaatt gcaatgaatc ctattgtaat
     5281 gagtcctatt gcagaaacac ccgacgccaa accatcgagt ccatcaatta agttaattgc
     5341 atttgtaata gcaacaatcc aaatcacagt aattggaata ctaagaaatc caaaatgaat
     5401 cgttgtaccc attggcaacg aaataaaatc aatagtcaca ccataaaaag caactactaa
     5461 ggcagcggca atttgaccag ccaattttat atacggtttc aaatcgtaga tatcatctac
     5521 aagcccaagt acgtacataa taatcgcacc aataataagt ggtttgattt ctgtttcaat
     5581 aggatgacca atccaaatac ctattaaaaa tgaaaagaga atcactgtac cacccataac
     5641 tgaaataggt ttagtgtgta cttttctaaa atttggttta tcaactaaat ttaatctttt
     5701 cgatattgca ataacaattg gtgttatcgt caaactgaca atcattgtta ctgcaactag
     5761 taataatgta accatttatt caccttcatc gatattaatt gtttttaacg ttatatttat
     5821 ttaatattgt ctttatagaa tgatatatct attttcttcg tatatcttat agctttatta
     5881 taaattaatt cgctcaatta atgatatcat atttacaact atacgattca tttcttatat
     5941 atcgcctatt attcattttt tcatcatatc atttaaggca acattttaac atcaaagtct
     6001 atatcataca ttaattttat atgtaaacta atgacaaatt gtaagttttc acttacaata
     6061 gctagtggtc aattaaagga gtcgattcag acatgttcga agcatttata tacaatatat
     6121 ctgttatagt cgctggaatc tatttattcc atcgcttaca gtattcagaa aacaaacgta
     6181 tggttttttc taaggcttat gtcactgttt taatgacaat cgtatcatta ttattatctg
     6241 tctaccctat cccttatcgt gaagattatt taattcactt aacattcgtt cctttattgt
     6301 ttttaggtag atttacaaat atggtctata cattatctgc cacagtaatt gtagcaattg
     6361 ttgaaattgt agtatttaac aactcgatta tgtacggtgt tacgttgatt gtaattgccg
     6421 cagtaacaag tgctattgga ccatttttaa aacaaaatga tgtgctatca ttattaatac
     6481 ttaatgttgt tacaataatc attttatttg gtgtcgcatt agtgagtcct atttacacac
     6541 tatcggaagt tatcatttta ataccaattt cattaattat cactttagct tctgcgataa
     6601 catttgtcga tatttggcat ttcttctcac tcgtaaatcg ttatgaaaac gaagataaat
     6661 atgattactt aacaggctta ggcaatgtaa aagaatttga tagacattta aatgaaattt
     6721 cacgaaaagc tgaaaaagaa catcaaagta tcgcattatt attaatcgat atcgatggat
     6781 ttaaagatgt caatgatacc tactcacaca aatcaggtga tgctgtatta aaacaaatgt
     6841 ctcaattact taaaaactat gtgccgaatc aatttaaaat ttttagaaat ggtggcgaag
     6901 agttctcagt tgtcattcac aattattcac ttgatcaaag tgttaaatta gctgaaaata
     6961 ttcgttcggg tgttgaaaaa tcatcattcc atttaccaaa caaagaagtt attaaattgt
     7021 cagtatctat cggtgttggt tatttaacag atgacgatcc aaaatcacag cgtaaagtgt
     7081 ttaaagatgc agacgatatg gtgcatgtag ccaaaaatca agggcgaaac aaagtaatgt
     7141 ttaaccctat tatcaattta taacaacgac aaaactgtta atcctttgct attattaaat
     7201 catagtataa tagcaaagat taacagtttt tcttatttaa atttgaacca tacaagttca
     7261 tcatactaac ataaagtctc actattgaaa gttgcaacaa caagttgtaa acttcaattg
     7321 ttcaaataaa taacacatat cattggaggt gaattgatat gccagattca atcacaatta
     7381 tagatgaaaa caaagtgatt gatgttgtat taattgcagg tagaatttta cttgaatcag
     7441 gtgctgaaac atatcgagtt gaagatacaa tgaaccgtat cgcacatagt tatggtcttc
     7501 ataatacata tagttttgtc agttcaactg caattatttt ttcattaaac gatcgaacaa
     7561 gtacaagatt aattcgtgta caagagcgta caacagattt agagaaaatc gctttaacga
     7621 atagtctttc acgtaaaata tcaaataaag aactcacaat tgatgaagct aaatctgaat
     7681 ttattcattt acagcatgca tcattacaat attctttttt aacgaatttc tttgcagctg
     7741 ccattgcatg tggcttcttc ctatttatgt ttggaggtgt cgcatcagat tgttggattg
     7801 cagtcattgc tggtggatcc gcatttttaa cattcagctt tgtgcaacgc tatatacaaa
     7861 ttaaattttt ctcagagttt gttgcagccg ctgtggtcat atcaattgca gctacattta
     7921 ctaaattagg tattgcaacc aatcaagata tcattactat agccagtgtc atgccacttg
     7981 tccctggtat attaattacc aatgccattc gagatttatt agcgggtgaa ttacttgcag
     8041 gtatgtctcg cggtgttgaa gctgcattaa cagcattcgc aatcggtgct ggtgtcgcta
     8101 tcgttttatt aatcatttaa ggaaggactg ttaaagcatg ctattttatt tatttcattt
     8161 tacaatcagc tttatatcaa cagtactttt ctctatcatt ttcaatgcac ccaaacgtct
     8221 cttagtagca tgtggatttg taggtgccat tgcatggacg atttaccaat taacggtaga
     8281 tttagagttt ggaaaagttg gcgcttcatt tttgggaagc ttaattttag gcttaatgag
     8341 tcatactatg agtcgcagat ataaacgacc ggtaattata ttcatagtgc caggcattat
     8401 accattagta cctggtggtg cagcttatca agcgactcgt tttttagtat cgaatgatta
     8461 tacaagtgct gtaaatacat ttttagaagt tacactgatt tcaggtgcga ttgctttcgg
     8521 tatattagtt tctgaaattc tatattacct atacacacgt atcaaacaac tgtatggtaa
     8581 aatcaaaggt aagacatata aaaaatctta caacatgaat aatagagttt aaggggtcga
     8641 atataatgaa gaaccaattg atagatagat taacaagata tacgacaatt gatacgcaat
     8701 ctgatccaaa atctacaaca acaccttcaa ctgaaaagca atgggatttg ttacatttat
     8761 tagaaaaaga attacaacaa ttaggattgc caactgattt agatgaaaat ggctacttat
     8821 ttgctacatt agaaagtaac atcgatgtcg acgtcccaac agttggattt ttggcgcatg
     8881 ttgatacatc acctgatttc aatgcttcaa atgttaaact gcaaattatt gaaaactatg
     8941 atggtaagcc atacaaacta ggcaatacta aacgtgtctt agatcctaaa gtatttccag
     9001 aacttaacag tttagttggt catacattaa tggtaactga tggtacatcg ttactaggtg
     9061 cagacgataa agcgggtatt gtggaaatta tggaagctat ttgttattta caagaacatc
     9121 cagaaattaa acatggtacc attcgcattg gatttacacc agacgaagaa atcggtcgtg
     9181 gtccacataa atttgatgtt gaccgcttca atgccgattt tgcttatact atggatggta
     9241 gtcaatatgg agaattacaa tatgaaagct ttaacgctgc tgaagcgatt attacatgcc
     9301 acggtgtgaa tgtacatcct ggttcagcta aaaatgcaat ggtaaacgca atacgtttag
     9361 gtgaacaatt cgatagtttg ctacctgata gtgaagttcc ggagcgaaca gaaggatacg
     9421 aaggctttta tcacttaatg aactttgaag gaactgttga aaaagcaact ttgcaataca
     9481 ttattcgtga tcatgataaa aaacaattcg aattgcgtaa gaaacgtatt ttagaaatac
     9541 gtgacgatat caatgcccat tttgaaaatt atccagttaa agttgatata tcggatcaat
     9601 atttcaatat ggcaaaaaaa atattaccat tgcctcatat tattgatata cctaaacgtg
     9661 tctttgccaa attagatatt ccagcaaaca ctgaacctat tcgcggtggt acagatggtt
     9721 cacaattatc atttatgggg ttaccaactc caaacatctt tacaggttgc ggtaacttcc
     9781 acggcccata tgaatatgca tccattgatg tcatggaaaa agcagtacaa gtaatcattg
     9841 gaattgtaga agatatcgct gaaaatcact aaaaacaaac gattatatac tagttcaact
     9901 caagcttaat taatataaaa aatcacgcta acattcagtg caatgatagc gtgatttttc
     9961 atatttttta cgtatacttt cgatcttcta attcgttttg ctaaccatca taaatgttat
    10021 taaccatcat gacagcatca ccaatttagt ccttctttac taaacctcaa cattaaaatg
    10081 tgttttcaac agttttaaag actgaacagt ataatgccta atttgtaatc ccattttaaa
    10141 gtcagtataa ctttccggca tatcgataaa ggtattaaac attgctgtaa ccccttgtga
    10201 ttcaaataaa tcaaactttt cagcagttgc acaaattgca atggcaacct tttgatgttt
    10261 atgacaaagt tctgcaatac gcaatgttgt cgtttctagc aactgatcat tttcgtttaa
    10321 tccttctcca aaaataatta aatccgcttg ttcaactaaa ttttctaaat gtgttagttg
    10381 gtctactaat gcatgactgg ttaatatttc agcttgatac agtccattca agactgctgc
    10441 aattccacca ccagcaccac cacgttcaac tggaccaatt gcaattttca attcactttt
    10501 aaataactca ctaaaatacc aaattaaatt atcgatttct gctgcttgat tatgattcaa
    10561 ctgatgcgca tcataagttt gcatgatttc actttgctta ccatataatc gacttgaaaa
    10621 atccgacatt acttgaattc ttgctgtttc cattttaggg tgtaagtttg acatatccat
    10681 acgacgaata tatttaatta caccagcacc ttgtctcata tctacgacac gcccttcgtc
    10741 atcatagaat tgagcaccta atgcttgtaa catacctgca ccagcatcaa aactatcaat
    10801 cccacctagt gaaattacaa catgttttgc gtcgttatct aatgcatgtt taatcatttc
    10861 tcctaaacca taacttgttc gttcaacaat tggtttttta ccttttaaaa ataaattccc
    10921 ctcgataacg gtcatccctg tatcagtttg tccgtaaaca ccttcaactt cattcatatc
    10981 tgcatcatgt actggtatac gatacttttg cccagattgc cataaaaata cagaatctaa
    11041 taattcatgt cttccattaa acaatggtac ttgaactaca tctgcagttt caatttggct
    11101 tgcaactgcc tcttcaacat atctattagc ttgataactc gaaataattc catgaaactc
    11161 atccatggct actaatactt tcataacctt gaccacctta ctttattatt tgttgtgata
    11221 cgttttttat tcttaaaaga ttaatcttaa attttagatt ttatctcgtg attatatgcg
    11281 aacattttac atgacatgat tattaattat tccagtaaat aacagtatgt ttcttctggc
    11341 ttagcatgta tttcctatta aactaactta caaatcatgt ttaaattttc ttattggatt
    11401 cgtcgttttc caaaatattt tcaataaaaa tactcgaata cattatacat atgtttgtaa
    11461 aaaagtacta acttaactac ttctataggt tacaaaaaat aaaaggtcag aacatcatta
    11521 tagccgaact accctgattc acacgaattt aagttgtgct attcacgtct agtagtgtaa
    11581 ggcaaaatgt tccaacccta tattttcatt attcttctgc ttgtgctaat gacgacacat
    11641 taatatcacc gtggtctcga ttccaaacca tttcaccatt tacaaaataa aatgcttgag
    11701 gtgattcatg tttaacattc gtttttttag caatataatc tgacaaatcg cgttcttgtt
    11761 ggacaatcaa ataataaccg tccatatcgc gttcatataa aaatttatta aattgatcgt
    11821 acgcatttgc cgatattgga caagtttcac tatgttttaa tacaaaaaca tatttatttt
    11881 cctcaataac ctgttcaaat tggtcaattg aacttagctt tatagccact ctattcacct
    11941 ctaaaaatat ttatcacatt taaatagcat ctgcgtgaca tttttataca tatagttaat
    12001 atcaatgttt accattatac acatagtaag ttgacatgtt aaccataaat tcaaaatttt
    12061 taactttgaa aaatgattat agttattttt cttctaattt ttcaagcttt ttttcaaagg
    12121 ctttatcgcc gtgagttata tctataccct ttttcggcaa cttatctaca tcgacttttg
    12181 ataacttctc actaaccttt attgtttcaa tacgtgtatt ataatagttc tgcagactgt
    12241 aatacatttc tattgcgttt ttccttgcat tattaacatg cttatcacta atattagttt
    12301 ggttaatatc ggtaatttgt ttttcaatca ttggcataat gtgattttta atcgcgcctt
    12361 ttacttcatt ttctttacta tcatctaggt tcttcttcgc agtatctctt aacgctttat
    12421 tattatgttc taattttgtc gtaagattag ttgcttcact tttattatca gctaatttaa
    12481 tttctgattc aactttgtat ctattttttt caaattgttt cgtataatct aaaatgtctt
    12541 cgttatactt gatagattga ttacataaac ctatgaattt ttttaattga tatatcgcat
    12601 ccttcttctc atttgcaagc gtcatatatt ctttttttaa tttcttaact ttcattgtat
    12661 catcaggcaa attttttgct gacttataat atgcttcaaa tttaggtatg agatggtttt
    12721 taacatcttc ttgtagtgcc ttaaattctt tactattttt atcagttgta tcagttttac
    12781 ttagatgatc aatttctttc aaatgtatat tatccatgac atgttgtaat tctttttgtt
    12841 tttgctcaac atctttaaat tgcttagtaa attgatgttg tgcctctttt tctttattac
    12901 cacaagcact tattactaca aataaaatcg ctaaaacagc gataataaca atttttttca
    12961 tgattgcact ccttaacaga ttcattatac aaaaacatgt ttattatgaa aatgaattat
    13021 gttatagtat tccagacttt atcgtgatta aattaatttt caatatcaaa ggagtttatc
    13081 atgtattcaa atgttcaacc attcattaat agtgatttaa ctaattgttt tcaatcacaa
    13141 tacaccgaaa ttgaatcatt attattcaac ctcttagaca gcccagtaaa atatacaaaa
    13201 catattggtg gtacgcatca ttttaaatat tcaacagagc caattttaga tattttagta
    13261 ggtgtagaaa atttgcatga tattacatcc ttagatgaaa aacgtttaaa ttatgttggg
    13321 ttttatcgct tgcatcataa atataataag aaagttatga tggcgaagtt taataatttt
    13381 catgaactaa aacaacaggt gcgtctacat atcattcaaa tgaataccca aacatttgaa
    13441 tcttatcttg cacttgatta tctcttatcg actaatgatg agattgcttt acaattcaat
    13501 actaaaaagc atcaaatatt gcaacatagc tttacaatta gacaatatga gatgcaaaag
    13561 caaaaatact ttgaaaaact atgtaaaaaa tacttataac gacaatagtg
//
LOCUS       DAPSKH010000067        13025 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPSKH010000067 DAPSKH010000000
VERSION     DAPSKH010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 13025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13025
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.067"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            57..1043
                     /locus_tag="RPH49_002261"
     CDS             57..1043
                     /locus_tag="RPH49_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylinositol-specific phospholipase C"
                     /protein_id="HDY5125382.1"
                     /translation="MKKCIKTLFLSIILVVMSGLYHSAHASDSLSKSPENWMSKLDDG
                     KHLTEINIPGSHDSGSFTLTDPVKSVWAKTQDKDYLTQMKSGVRFFDIRGRASADNMI
                     SVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREYY
                     YNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIKSGYGADTSGIQWADNATFE
                     TKINNGSLNLKVQDEYKDYYDKKVEAVKNLLAKAKTDSNKDNVYVNFLSVASGGSAFN
                     STYNYASHINPEIAKTIKANGKARTGWLIVDYAGYTWSGYDDIVSEIIDSNK"
     gene            1263..2033
                     /locus_tag="RPH49_002262"
     CDS             1263..2033
                     /locus_tag="RPH49_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5125383.1"
                     /translation="MMKRLNKLVLGISLLFLVISITAGCGMGKEAEIKKSFEKTLSMY
                     PIKNLEDLYDKEGYRDDEFDKNDKGTWTISSEMAIQKKGEALNIKGMVLKLNRNARSA
                     KGFYYVNAIKKDENGRPLDNQIEYPVKMIDNKIIPTKDIKDEKIKKEIENFKFFAQYG
                     NFKDLSKYKDGDISYNPEVPSYSAKYQLTNDDYNVKQLRKRYNIPTNKAPELLLKGSG
                     NLDGSSVGYKKIEFTFVEKKGENTYFTANLHFKPSEDE"
     gene            2098..2868
                     /locus_tag="RPH49_002263"
     CDS             2098..2868
                     /locus_tag="RPH49_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5125384.1"
                     /translation="MMKRLNKLVLGISFLFLVISITAGCGIGKEAEIKKSFEKTLSMY
                     PIKNLEDLYDKEGYRDDQFDKNDKGTWIINSEMVVQPKGERMKSKGMVLYMNRNTKTT
                     TGKYIVSETLHDEDGRPKSKDKEYPVKMVDNKIIPTKGIKDENIKKEIENFKFFAQYG
                     NFKDLSKYKDGDISYNPEAPIYSAKYQLTNNDYNVKQLRKRYDIPTNKAPKLLLKGSG
                     NLKGSSVGYKKIEFTFVEKKGENIYFSDGLQFNPSEDK"
     gene            2966..5203
                     /locus_tag="RPH49_002264"
     CDS             2966..5203
                     /locus_tag="RPH49_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020808042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5125385.1"
                     /translation="MQRDYLIRVETESMSDFKRLNGLMIGFVIKGEAHIYDENNMTQC
                     NSGDIFIINHRDLYRFQLQQDGIICYIQFQMKYLADKFDDVHCLYFHLTDATTTKNIH
                     QLRNIMARLVSTHIRHNELSKLTEQQLVIQLLMHMIHYVPRTYHSNQSILNDDKVNQV
                     CDYIELHFHEDLSLSELSEYVGWSESHLSKKFAESLGVGFQHFLNTTRIEHAKLDLTY
                     TDETITDIALQNGFSSAASFARTFKHFTHQTPKQYRGDRPAITENQQSAQHNYHDREL
                     ILLLNDYIEEMNHFIEDIEKMNYKEIAFKPTNQQLNQFNHIIQVGYLRNLLNTQYQSQ
                     LLTCHHDFHVNEVLAYDVMPYIMKKLNAPFTYDAEISNIFYDIDLCLDFLLDHNFSLT
                     MHLDQYDSRDYIDAFKVFIHHVALHVSHRKDLKFNLYVTTLHTSLIEMIDYFKALFPN
                     GGLYIHLDQATERHLPLLKRLEPHINHFVFDANSNDAVDFNKMNDDEFKTASQIIINK
                     TNYLIDLMHRHNLKRPLILLNWNTLTGDTFITNGEYFRGGIIIEQLLKLSSKVEGIGY
                     WLNYDLHVSHCRNERDYMNSIELFHQYNGKRPVYFTALLFNKLTSNILYSDDTCIVTG
                     TDSNFQILLYDAKHFNPYLALDNQMNMRATEMIHLNINALEDGMYKIKHFTLDKENGA
                     LFNLWRKHHTIHGMDKDSIDYVNRMSFPKLEVYDIDITETLALNIKMITNGIHLIEVK
                     RYPSS"
     gene            5354..6532
                     /locus_tag="RPH49_002265"
     CDS             5354..6532
                     /locus_tag="RPH49_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDY5125386.1"
                     /translation="MNQQLIETLKSKEGKMIEIRRYLHQHPELSFHEDETAKYIAEFY
                     KGKDVEVETNVGPRGIKVTIDSGKPGKTLAIRADFDALPITEDTGLSFASQNKGVMHA
                     CGHDAHTAYMLVLAETLAEMKDSFTGKVVVIHQPAEEVPPGGAKAMIENGALDGVDHV
                     LGVHVMSTMKTGNVYYRPGYVQTGRAFFKLKVQGKGGHGSSPHMANDAIVAGSYFVTA
                     LQTVVSRRLSPFETGVVTIGSFDGKGQFNVIKDVVEIEGDVRGLTDATKATIEKEINR
                     LSKGLEDMYGVTCTLEYNDDYPALYNDPEFTEYVAKTLKEADLEFGVEICEPQPPSED
                     FAYYAKERPSAFIYTGAAVEDGEIYPHHHPKFNISEKSLLISAEAVGTVVLDYLKGDN
                     "
     gene            6534..7922
                     /locus_tag="RPH49_002266"
     CDS             6534..7922
                     /locus_tag="RPH49_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125387.1"
                     /translation="MNETYRGGNKLILGIVLGVITFWLFAQSLVNVVPNLQQSFGADM
                     GTISIAVSLTALFSGMFVVGAGGLADKIGRVKMTNIGLLLSIIGSALIIITNLPALLI
                     LGRIIQGVSAACIMPSTLAIMKTYYEGAERQRALSYWSIGSWGGSGICSLFGGAVATT
                     MGWRWIFIFSIIVAVLSMLLIKGTPETKSEVTNTHKFDVAGLIVLVVMLLSLNVVITK
                     GAALGYTSLWFFGLIAIVIVAFFIFLKVEKKVDNPLIDFKLFENKPYTGATISNFLLN
                     GVAGTLIVANTFVQQGLGYTALQAGYLSITYLIMVLLMIRVGEKLLQKMGSKRPMLLG
                     TFIVVIGIALISLVFLPGIFYVISCVVGYLCFGLGLGIYATPSTDTAISNAPLDKVGV
                     ASGIYKMASSLGGAFGVAISGAVYAGAVAATSIHTGAMIALWVNVLMGIMAFIAILFA
                     IPNDDKRVKDAK"
     gene            complement(8409..10070)
                     /locus_tag="RPH49_002267"
     CDS             complement(8409..10070)
                     /locus_tag="RPH49_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDY5125388.1"
                     /translation="MSVTEVIFSFLGGLGIFLYGLKIMGDGLQASAGDRLRDILNKFT
                     SNPVLGVIAGIVVTILIQSSSGTTVITIGLVTAGFMTLKQAIGVIMGANIGTTVTAFI
                     IGIDLGEYAMPILALGAFLIFFFKRSKINNIGRILFGFGSLFFGLEFMGDAVKPLASL
                     DGFKQLMLDMSTNPILAVIVGAGLTALVQSSSATIGILQEFYQQDLISLNAAIPVLLG
                     DNIGTTITAILASLAGSIAAKRAALVHVIFNLIGVIIFTIFLPVVIHLISLLQDVWHL
                     KPAMTIAVSHGIFNITNTLIQLPFVAGLAWIVTKLVPGKDIADDYKPQHLNKDLVYHA
                     PGVALQETQKELQNVGQIVLSMFEDIREITKDDKKLIKKLEQKHQAVETINDSIRNYL
                     VRISTKAITKADVERLAVMFDVNRSILKVAELTEEYVAQLKRQHDEDIRITEDAQRGM
                     DKLFNHVAESFDKAIDMLDVYDKTKKDEIVERSRESFNIEHKLRKGHIKRLNRGECTT
                     KGGLLYIDMIGVLERIGYHSRNVSEALVGLNDDVPTDEEIATTEI"
     gene            complement(10397..12172)
                     /locus_tag="RPH49_002268"
     CDS             complement(10397..12172)
                     /locus_tag="RPH49_002268"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDY5125389.1"
                     /translation="MYYSYGNYEAFARPKKPENVENKSAYLIGSGLASLAAACFLIRD
                     GQMEGSKIHILEELPKAGGSLDGENMPLKGYVVRGGREMENHFECLWDLFRSIPSLEI
                     DNASVLDEFYWLNKEDPNYSRCRVIEKQGQRLVTDGDFTLTKKAIKEILDLCLTNEED
                     LDDVKITDVFSDDFFNSNFWIYWKTMFAFEPWHSAMEMRRYLMRFVHHIGGLADFSAL
                     KFTKYNQYESLVLPMVEYLKSHGVQFEYDVKVEDIKVDVTTSQKIAREILIHRHGKAE
                     SIKLTVDDLVFVTNGSITESSTYGDNDTPAPPTDELGGSWTLWKNLARQSPEFGNPDK
                     FCQNIPQKSWFVSATSTTNNKDIIDTIESICKRDPLAGKTVTGGIITINDSAWQISFT
                     INRQQQFKDQPKNEISTWIYALYSDVNGDYIKKPITECSGNEICQEWLYHLGVPTDKI
                     EDLAKHASNTIPVYMPYITSYFMTRAIGDRPLVVPHQSQNLAFIGNFAETERDTVFTT
                     EYSVRTAMEAVYQLLNINRGIPEVINSTFDLRVLMDAIYELNDHQDLREITKDSKMQK
                     LALAGFLKKIKGTYIETLLKEHKLL"
     gene            12523..12996
                     /locus_tag="RPH49_002269"
     CDS             12523..12996
                     /locus_tag="RPH49_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1648 domain-containing protein"
                     /protein_id="HDY5125390.1"
                     /translation="MSKIRSFTILSLLIYLAMTCYTVVTYPKLPTKVPIHYNLAGDAD
                     NFADKWVLLLINSAFIVIWLIFFIAGRYYERFAKWSHYNHTPREIRAIKLFLSTLNLE
                     IMSYMSIFTVLEIWQIQHHHQFNLLWFNMIFIIIIGLTLVIFCLLPTIHKMRDSQ"
BASE COUNT         4472 a         2001 c         2370 g         4182 t
ORIGIN      
        1 ttttatttaa aaaagatgta taattaatgt attaaatata gaaagaagtt gatattatga
       61 aaaagtgtat taagactttg tttttaagta tcattttagt agtgatgagt ggtttatatc
      121 attcagcaca tgcgtcagat tcgttgagta aaagtccgga aaattggatg agtaaacttg
      181 atgatggaaa acatttaact gagattaata taccgggttc acatgatagt ggctcattca
      241 ctttaactga tccagtaaaa tcagtttggg caaagactca agataaagat taccttaccc
      301 aaatgaagtc aggagtcagg ttttttgata ttagaggcag agcaagtgct gataatatga
      361 tttcagttca tcacggcatg gtttatctgc atcatgaact agggaaattt ttagatgatg
      421 ctaaatatta cttgagtgct tatccaaacg aaacaattgt gatgtctatg aaaaaggact
      481 acgatagcga ttctaaagtt acgaagacat ttgaagagat ttttagagaa tattattata
      541 ataacccaca atatcagaat cttttttaca caggaagtaa cgcgaatcct actttaaaag
      601 agacaaaagg taaaattgtc ctattcaata gaatgggtgg tacatacata aagagtggtt
      661 atggtgctga cacgtctggc attcaatggg cagacaatgc gacatttgaa acgaaaatta
      721 ataatggtag cttaaattta aaagtacaag atgagtataa agattactat gataaaaaag
      781 ttgaagctgt taaaaattta ttggctaaag ctaaaacgga tagtaacaaa gacaatgtat
      841 atgtgaattt cttgagtgta gcgtctggag gcagcgcatt taatagtact tataactatg
      901 catcacatat aaatcctgaa attgcaaaaa cgattaaagc aaatgggaaa gctagaacgg
      961 gttggctgat tgttgactat gcaggatata cgtggtctgg atatgatgat atcgtaagcg
     1021 aaattataga tagtaataaa taaggattca ataatgatat taagacgagt atgaaaatag
     1081 ttagattcta attattttca ctactcgttt ttattttgaa aataagtaat aattcaacaa
     1141 tattataaat tgaacagatt gtttatggaa tttttgataa tattaaagtg aaaaagtgtt
     1201 ataaattgaa attaatgtgt aatttgcaaa agtaaatcat tttaaaagaa gagagttgta
     1261 agatgatgaa acgattaaac aaattagtgc ttggtattag tcttctgttt ttagtcatta
     1321 gtatcactgc tggttgtggc atgggtaaag aagcggaaat taagaaaagt tttgaaaaaa
     1381 cgttgagtat gtatccgatt aaaaatctag aggatttata cgataaagaa ggctatcgtg
     1441 atgacgaatt tgataaaaat gataaaggaa catggactat tagttctgaa atggcaattc
     1501 agaaaaaggg agaagcctta aatataaaag gtatggtttt gaagttaaat agaaatgcaa
     1561 gaagtgcaaa aggattttac tatgttaatg cgataaagaa ggatgaaaat ggcagacctc
     1621 tggataatca aatagaatat cccgttaaaa tgattgacaa taaaatcatt ccaactaaag
     1681 atatcaaaga tgaaaaaata aaaaaagaaa tagaaaactt taagtttttc gcgcagtatg
     1741 gcaactttaa agatttatcg aagtacaaag atggagatat ttcatataat ccagaggtgc
     1801 cgagttattc agccaaatat caattaacta atgatgatta taatgtaaag caattacgta
     1861 aaagatataa tataccaacg aataaagcgc cggagttatt attgaaaggt tcaggaaatt
     1921 tagatggttc atcagttggc tacaaaaaaa ttgaatttac tttcgtagag aaaaaaggag
     1981 aaaacactta ctttacagct aacctacatt ttaaaccgag tgaggatgaa taatcgtgac
     2041 taataaagag tatgaaatcg attcaaggaa acaaaataaa aagaagagag ttgtaaggtg
     2101 atgaaacgtt taaataaatt agtgttaggt attagtttct tatttttagt cattagtatt
     2161 actgctggtt gtggcatagg taaagaagcg gaaataaaga aaagttttga aaagacattg
     2221 agtatgtatc caattaaaaa tctagaggat ttatacgata aagaaggcta tcgtgatgat
     2281 cagtttgata aaaatgataa aggcacatgg attattaatt ctgaaatggt tgttcaacct
     2341 aaaggggaac gtatgaaatc aaaaggtatg gttctatata tgaatagaaa cactaagact
     2401 acaaccggga agtatatagt gagtgaaaca cttcatgatg aagatggtag acctaagagt
     2461 aaagataaag aatatcccgt taaaatggta gacaataaaa tcattccaac taaaggtatc
     2521 aaagacgaaa acataaaaaa agaaatcgaa aactttaagt tcttcgcgca atatggcaac
     2581 tttaaagatt tgtcgaagta caaagatgga gacatttcat ataatccaga agcgccgatt
     2641 tattcagcta aatatcaatt aactaataat gattataacg taaagcaatt acggaaaaga
     2701 tatgatatac cgacgaataa agcaccaaag ttattgttga aaggctctgg aaatttaaaa
     2761 ggttcatcag tcggatacaa aaaaattgaa tttactttcg tagagaaaaa gggagaaaat
     2821 atatatttta gtgatgggct acaatttaac ccaagtgagg ataaataacc tcactgcctc
     2881 ccacacgatt caatatgaaa ttcaaatatg ttgctgtaaa ataatgtaaa ataaacgtat
     2941 tcatattact gaattgaggg atagtatgca acgtgattat ttaattcgag tagaaactga
     3001 gagtatgtca gatttcaaaa ggctcaatgg tttaatgatt ggttttgtta ttaaaggtga
     3061 ggcgcacatt tatgatgaaa ataatatgac gcaatgcaac agtggcgaca ttttcatcat
     3121 taaccaccgc gacttgtatc gatttcaact tcaacaagat ggcatcatat gttatatcca
     3181 attccaaatg aaatatttag cagacaagtt tgatgatgtg cattgtctat attttcactt
     3241 aacagatgcg accacaacca aaaatataca tcaactgaga aatataatgg caagactggt
     3301 ttcaacacat attcgacata atgagttgtc taaattgact gagcaacaac ttgtgattca
     3361 gttgcttatg catatgattc attatgtccc gcgtacatat cattcgaacc aaagtatctt
     3421 aaatgatgat aaagtgaatc aagtatgcga ctatatcgag ttacattttc atgaagactt
     3481 aagcctttcg gaattaagcg aatatgttgg gtggtcagag agccatctgt ctaaaaagtt
     3541 tgcagaatcg ctaggtgtag gattccagca tttcttaaat acgacgcgaa ttgagcatgc
     3601 gaaactcgat ttgacataca cagatgaaac gattactgat attgcattgc aaaatggctt
     3661 ttcaagtgca gcgagctttg cgagaacatt taaacacttt acgcatcaaa cgcctaaaca
     3721 atatcgaggt gatcgtccgg caatcactga aaatcaacaa tcggcacaac ataattatca
     3781 cgaccgtgaa ttgatattac ttttaaatga ctacattgaa gaaatgaatc atttcattga
     3841 agatattgaa aagatgaact ataaagagat tgcctttaaa ccaactaatc aacaactaaa
     3901 tcaatttaat catattattc aagtgggcta tttgaggaat ttgctcaata cacagtatca
     3961 atcacagtta cttacatgcc atcatgattt tcatgtcaat gaagtattag catatgatgt
     4021 gatgccatat attatgaaaa agctcaatgc gccattcacg tatgatgcag agatttcgaa
     4081 tatattttat gatatcgatt tgtgtttaga ctttttatta gatcataact ttagtttgac
     4141 aatgcatttg gatcagtatg actcacgtga ttatatcgat gcattcaaag tatttatcca
     4201 tcacgttgcc ctgcatgtca gtcatagaaa agatttgaag ttcaacttgt atgtgacgac
     4261 attgcacact tctttgattg aaatgattga ttattttaaa gcgttattcc ctaatggtgg
     4321 cttgtacatt cacttagatc aagctacgga aagacatcta ccattgttga aacgacttga
     4381 gccacacatc aaccattttg tatttgatgc caattcaaat gatgctgttg attttaataa
     4441 aatgaatgat gatgaattta aaaccgcgag tcaaataatt attaataaaa cgaattacct
     4501 tatcgactta atgcatcgcc ataacctaaa gagaccactt attttactca attggaatac
     4561 attgacgggt gatacattta ttacaaacgg cgaatatttt agaggtggta tcatcattga
     4621 gcaattatta aaattaagtt ctaaagtaga gggtatcggg tattggttga attatgattt
     4681 gcacgtcagt cattgtagaa atgaacggga ttatatgaat tctattgaac tgtttcatca
     4741 atataatgga aaacgtccgg tctatttcac ggcattgcta tttaataaat taacaagcaa
     4801 tattttgtat tctgatgata catgtattgt cacggggact gattcaaatt ttcaaatatt
     4861 gttatatgat gcaaagcatt ttaatccgta cttagcgttg gacaatcaaa tgaatatgcg
     4921 tgcaacggaa atgatccatt tgaacattaa cgccctagaa gacggtatgt ataagattaa
     4981 acattttacc ttagataaag aaaatggtgc gttatttaat ctttggcgca aacatcatac
     5041 gatacatggc atggacaagg actctataga ttacgttaat cgaatgagtt ttccgaaatt
     5101 agaagtatat gatatagata tcacggagac actggcatta aacattaaaa tgattacgaa
     5161 tgggattcac ttaattgaag taaaacgtta cccaagttca taaaatgatc acaaatcaca
     5221 aattttgata tacataattt gtgatttttt atattcaaag ctaaaattgc aaaaaattaa
     5281 tggttaacat ctctgttgtt gtcaatataa ataatgatta atcatttatg atgtaactaa
     5341 ggagatgaag gatatgaatc aacaattaat tgaaacttta aaatctaaag aaggcaaaat
     5401 gattgagatc agacgttatt tacatcagca tccagaatta tcttttcatg aagatgaaac
     5461 ggcgaaatac atcgctgaat tttacaaagg taaagatgtg gaagtagaaa cgaatgtcgg
     5521 accacgtgga attaaagtaa cgattgattc agggaaacct ggtaaaacat tagcaatccg
     5581 tgcagacttt gatgcattac ctattactga agatacagga ttatcttttg catcacaaaa
     5641 taaaggtgtt atgcacgcat gtggtcacga tgcacataca gcatacatgc ttgtattagc
     5701 agagacgctt gctgaaatga aagatagttt tacaggaaaa gtcgttgtga tacatcaacc
     5761 agctgaagaa gtaccaccag gtggtgctaa agcaatgatt gaaaatggtg cattagacgg
     5821 tgttgatcat gtattaggtg tacacgtcat gagcacaatg aaaacaggta atgtgtatta
     5881 cagacctggt tatgttcaaa caggacgcgc attcttcaaa ttgaaagttc aaggtaaagg
     5941 tggtcatggt tcatcaccac atatggccaa tgatgccatt gttgcaggta gctacttcgt
     6001 cacagcgtta caaacagttg tatctagacg actaagtcca tttgaaaccg gtgttgtcac
     6061 aatcggttca tttgacggta aaggtcaatt caatgtcatt aaagatgttg ttgaaattga
     6121 aggtgatgta cgtggattaa cagatgctac aaaagcaaca attgaaaaag aaattaaccg
     6181 tttatcaaaa ggcttagagg atatgtatgg tgtaacttgc accttagaat ataacgatga
     6241 ttatcctgca ttatataatg atccagagtt tactgagtac gtggctaaga cgttaaaaga
     6301 agcagacctt gaatttggtg tcgaaatatg tgaaccacaa ccaccttcag aagactttgc
     6361 atactatgct aaagaacgtc caagtgcctt tatttataca ggtgcagcgg tggaagatgg
     6421 tgaaatttac ccacatcatc atcctaaatt taacatttca gaaaaatcat tacttatttc
     6481 ggcagaagct gtagggacag ttgttttaga ttaccttaaa ggagataact aacatgaatg
     6541 aaacgtatcg cgggggcaac aagttaatct taggtattgt attaggtgtt attacatttt
     6601 ggttgtttgc acaatcactt gtaaatgttg taccaaattt acaacaaagt tttggtgcag
     6661 acatgggaac aattagtatt gcggtaagtc taaccgcact attttcaggc atgtttgttg
     6721 ttggagcagg cggcctagca gataaaattg gacgcgtgaa aatgacaaat atcggcttat
     6781 tattaagtat tattggttca gcattaatta ttattacaaa tttaccagca ttgttaattt
     6841 taggtcgtat tatacaaggc gtatcagcag cgtgtattat gccttccaca ttggccatta
     6901 tgaaaactta ttatgagggt gctgaacgtc agcgcgcctt aagctactgg tctatcggtt
     6961 cttggggtgg aagtggtatc tgttcactct tcggtggggc agttgcgaca actatgggtt
     7021 ggagatggat tttcatcttc tcaattatcg ttgccgtact ttcaatgtta ctcatcaaag
     7081 ggacgcctga aacgaaatca gaagttacca atacacataa atttgacgtt gcagggctaa
     7141 ttgttctagt agttatgttg ctaagtttaa acgttgtcat tactaaaggt gcagcacttg
     7201 gttacacatc attatggttc tttggtttga ttgcaatcgt aattgtagca ttctttattt
     7261 tcttaaaagt tgagaaaaaa gtagataatc cgcttattga ttttaaatta tttgaaaata
     7321 aaccatatac aggtgcaacg atttcgaact tcttattaaa cggtgttgca ggtacattaa
     7381 ttgtagcgaa tacattcgtg caacaaggtt taggttatac agcattgcag gcaggatact
     7441 tatcaatcac ttatttaatt atggtgttat tgatgattcg agttggtgaa aaattattac
     7501 aaaaaatggg ttctaagcga ccaatgttat taggtacatt cattgtggtc attggtattg
     7561 cacttatttc attagtattc ttaccaggca tattttatgt tatcagttgt gtcgtaggat
     7621 atttatgttt cggactaggc ttaggtattt atgcaacacc ttctacagat acagctattt
     7681 cgaatgcacc gttagataaa gttggcgttg cttcaggtat ttataaaatg gcttcatcac
     7741 ttggtggtgc attcggtgtc gcaattagtg gtgcagtata tgccggtgca gttgctgcaa
     7801 cgagcattca tacaggtgcg atgattgcac tttgggttaa cgtattaatg gggatcatgg
     7861 catttatcgc aattttattc gcgattccta atgatgataa acgtgtcaaa gatgcgaaat
     7921 aataacgatg acacgcccag tgttttgata ataatttaaa tgaaagtaaa gcaaattaaa
     7981 tgaggaaatg tatagagcag tgcatataga taaatctatg attggattaa cactaatata
     8041 aatataaatg aaaaaccatc cacttaaact tttaataagt taggtggatg gttatttatt
     8101 gcgttgttct aaaaattttg acacttatat ggaaagaaat atatataatg tgaaggttat
     8161 ggcaattcgc ttcaatgaag gcgacgtgta aaagtgtata ttaaatgatt cgaggtcaga
     8221 ctccgagaac agtgtccgtc atgcttaccg catactaatg aagcatcatt atatcagtgt
     8281 ttatagccga tttaagataa taaattttgc taaacaaaaa agccaaccca tgaatgttgg
     8341 attggctttt tacatgcatc tgaatctcta attttaaaaa aatatgaata taaataagac
     8401 agtaaaaatt aaatttcagt tgttgcaatt tcttcatctg taggtacatc atcgttaagg
     8461 ccaacaagtg cttcagaaac atttcgtgaa tgataaccga tacgttcaag aacaccaatc
     8521 atgtcgatat atagtaatcc gccttttgtt gtacattcac cacgattaag gcgtttaata
     8581 tgacctttgc gtagtttatg ttcaatatta aatgattctc tactacgttc tacaatttca
     8641 tcttttttcg ttttgtcata aacatctaac atgtcgatgg ctttatcaaa tgattcggca
     8701 acatggttga ataatttatc cataccgcgt tgtgcatctt ctgtaatgcg aatatcttca
     8761 tcatgttggc gttttaattg agcgacatac tcttctgtta gctctgctac ttttaaaata
     8821 gagcgattga catcaaacat aactgctaaa cgctcaacgt ctgccttcgt aatggctttt
     8881 gtagaaattc taactaaata atttcgaata ctatcattga ttgtttcaac agcttggtgc
     8941 ttttgttcaa gctttttgat caatttttta tcgtcttttg taatttcgcg aatgtcttca
     9001 aacattgata agacaatctg accaacattt tgtaattctt tttgagtttc ttgtaatgca
     9061 acaccaggtg cgtgataaac aagatctttg tttaagtgct gaggtttata gtcatcagca
     9121 atatctttac ctgggacaag ctttgtaact atccatgcta aacctgctac aaatggtaat
     9181 tgaatcaaag tatttgttat gttgaagata ccatgtgata ctgcaatcgt catcgctggt
     9241 tttaagtgcc atacatcttg taacaaacta atcaaatgaa tcacaactgg caagaaaatt
     9301 gtgaagataa ttaccccgat taagttaaag atgacgtgta caagcgccgc acgttttgca
     9361 gcgattgagc cggctaaact agctaagata gctgtaatcg ttgtaccaat attatcgcct
     9421 agtaacacag ggattgctgc gtttaagctg attaaatctt gttgataaaa ttcttgtaaa
     9481 ataccaatcg tcgcacttga actttgaact agtgctgtta accctgcgcc gacaatgaca
     9541 gcaagtattg gatttgtaga catatcaagc attaattgct taaatccatc taatgatgct
     9601 aaaggtttaa cggcatcacc cataaattct agaccgaaga atagagaacc gaaaccgaat
     9661 agtatgcggc caatgttatt gattttagag cgcttaaaga aaaagattaa aaatgcacct
     9721 aatgctaaaa ttggcattgc atattcgcct aaatctatac cgataataaa tgcagttacc
     9781 gttgttccga tattagcacc cattatcact ccaatggctt gtttcaatgt cataaatcca
     9841 gctgttacca gtccgattgt gataactgtc gtacctgaac tactttgtat taaaatagtt
     9901 acaacgatac ctgcaataac acctaatact ggatttgatg taaatttgtt taaaatatct
     9961 cgtagcctgt ctcctgctga tgcttgaagc ccgtctccca tgatttttaa gccgtaaagg
    10021 aaaataccta aaccacctaa aaaggagaaa atgacttctg taaccgacat ttccattatt
    10081 tcacctcaaa taagctttat atttagatta tcgcttataa ttgtaaattt aatgttaaga
    10141 ttaggtaaaa ttatttaaca atatatgtta tttgtatatg acttgtaaaa tatcatcact
    10201 tattatgtaa attttcagtg tgaaatggca ggtttgcaat cacttgttta acaaaatgat
    10261 gcaatcaatc atgtgacaat gttttggcaa taaaaaatca tgagagtgga acaacgaaat
    10321 aatttttatg aaaacatcat ttctgtccca gtctcatgat tcgaaatcac caaataaaat
    10381 tatttaatgt gcctcgttat aacaatttgt gttcttttaa taatgtctca atgtacgtac
    10441 cttttatctt tttaaggaat cctgctaatg cgagtttttg cattttcgaa tctttagtaa
    10501 tctcgcgcaa atcttgatgg tcattcagtt cgtatatggc atccattaag acgcgaagat
    10561 caaatgtact attgatgacc tctggaatac cacgatttat atttagtaat tgataaacag
    10621 cttccatggc agtacgaacc gaatattctg ttgtaaatac agtatctcgc tctgtttctg
    10681 caaagttacc aataaatgct aaattttgtg attgatgcgg aacgactaaa ggtctgtcgc
    10741 cgatagcacg cgtcatgaaa taagaggtaa tatatggcat ataaacagga atcgtattag
    10801 atgcatgttt tgctaagtct tcaattttgt cagttggtac acctaagtga tacagccatt
    10861 cttgacatat ttcattacca ctacattctg tgattggctt tttaatataa tcgccattta
    10921 catctgaata taaggcataa atccatgtag atatttcatt tttaggttgg tctttaaact
    10981 gttgctgacg attgattgta aaactgattt gccatgcaga atcattgatt gtaataattc
    11041 caccagtaac cgttttgcct gcaagtggat cacgtttaca aatgctttct attgtatcga
    11101 taatatcttt attgttagtt gtcgatgttg cagaaacaaa ccaacttttt tgaggaatat
    11161 tttggcaaaa cttatcagga ttaccaaatt caggactttg tcgcgctaaa tttttccata
    11221 gtgtccaact accacctaat tcgtcagttg gtggtgctgg tgtatcatta tcaccatacg
    11281 tagagctttc cgtaatacta ccgtttgtca caaagacaag atcatctaca gtcagtttaa
    11341 ttgactctgc tttgccatgt cggtgaatta atatttctcg ggcaattttt tgacttgtcg
    11401 taacatctac tttaatatct tctactttta catcgtattc aaattgaacc ccatgcgatt
    11461 ttaaatattc aaccataggt aatactaaag attcatattg attatattta gtgaatttta
    11521 aagctgaaaa gtctgcgaga ccaccaatat gatgaacgaa tcgcattaga tagcgacgca
    11581 tttccattgc agaatgccac ggttcaaatg caaacatcgt tttccagtaa atccaaaagt
    11641 ttgaattaaa gaagtcatcg gaaaatacat ctgttatttt gacatcatct aaatcttctt
    11701 cattcgttaa gcataaatct aaaatttctt taatcgcttt tttggtcaaa gtgaagtctc
    11761 catcggtaac taaacgttga ccctgttttt caataactcg acagcgagaa tagttagggt
    11821 cttctttgtt tagccaatag aactcatcta atacagacgc gttatcgatt tctaatgaag
    11881 ggatagatct gaataagtcc cacaaacatt caaagtggtt ctccatttca cgaccacctc
    11941 ggacaacata gccttttaaa ggcatatttt caccatcaag actaccacct gctttaggta
    12001 actcttctaa aatatgaatc ttcgaacctt ccatttgacc atccctaatt aagaaacaag
    12061 ctgccgcaag tgaagctaac ccagacccga ttaaataagc agatttgttt tctacatttt
    12121 caggtttttt agggcgcgca aatgcttcat aatttccata actgtaatac atatccacca
    12181 agtcctttcg tattagaata cactcagact ataccccttt gtgaattgca aatattagta
    12241 tttatattgg taaatttgac gaaattagat catttttata tttttgattt taaaaatttt
    12301 atcactcgaa tgtttttgga ttctgaggtg cgggacttgg aataattcga atcattatgt
    12361 ggcatgttaa acagctaaat ataagctatg cacatttaac aagcggatac tcctgacgca
    12421 attatagtat cattacatat tgtttaatcg tttggggtaa tgtaattaaa aggtaaaata
    12481 ggcagagtgt tatacataaa atgtaaagaa agaggcgata gaatgtctaa aatcaggtct
    12541 tttacaatat taagtctact tatttactta gctatgacgt gctatacagt agtgacctat
    12601 ccaaaattac caaccaaagt gcctattcat tataatttag caggggatgc tgataacttt
    12661 gctgataaat gggtactgct tttgattaat agtgcattta tagtgatttg gcttatattt
    12721 ttcattgcag gtagatacta tgaacgattt gccaaatggt cacattataa tcatacacca
    12781 cgtgaaattc gagcgattaa attattttta agtacgttaa atttagagat tatgagctat
    12841 atgtctatct tcacagtatt agaaatttgg caaatacaac accatcatca attcaattta
    12901 ctatggttta atatgatatt tatcattatc attggtttga cgcttgtcat attttgttta
    12961 cttcctacaa ttcataaaat gagagattct caataaaaat ataaactgtc atgatgcagt
    13021 tttga
//
LOCUS       DAPSKH010000068        12249 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPSKH010000068 DAPSKH010000000
VERSION     DAPSKH010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 12249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12249
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.068"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(322..969)
                     /locus_tag="RPH49_002270"
     CDS             complement(322..969)
                     /locus_tag="RPH49_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDY5125391.1"
                     /translation="MKFDNYIFDFDGTLADTKKCGEVATQSAFKACGLTEPSSKEITH
                     YMGIPIEESFLKLADRPLDEVALAKLIDTFRHTYQSIEKDYIYEFAGITEAITSLYNQ
                     GKKLFVVSSKKSDVLERNLSAIGLNHLITEAVGSDQVSAYKPNPEGIHTIVQRYNLNS
                     QQTVYIGDSTFDVEMAQHAGVPSAAVTWGVHDARSLLHSNPDFIINDPSEINTVL"
     gene            complement(1082..1630)
                     /gene="hxlB"
                     /locus_tag="RPH49_002271"
     CDS             complement(1082..1630)
                     /gene="hxlB"
                     /locus_tag="RPH49_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-3-hexuloisomerase"
                     /protein_id="HDY5125392.1"
                     /translation="MAEFSDYQLILDELKMTLSHVEADEFSTFASKILHAKHIFVAGK
                     GRSGFVANSFAMRLNQLGKQAHVVGESTTPAIKSNDVFVIISGSGSTEHLRLLADKAK
                     SVGADIVLITTNKDSAIGNLAGTNIVLPAGTKYDEQGSAQPLGSLFEQASQLFLDSVV
                     MGLMTEMNVTEQTMQQNHANLE"
     gene            complement(1632..2264)
                     /gene="hxlA"
                     /locus_tag="RPH49_002272"
     CDS             complement(1632..2264)
                     /gene="hxlA"
                     /locus_tag="RPH49_002272"
                     /EC_number="4.1.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019834869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hexulose-6-phosphate synthase"
                     /protein_id="HDY5125393.1"
                     /translation="MELQLAIDLLNKEDAAELANKVKDYVDIVEIGTPIIYNEGLPAV
                     KHMADNISNVKVLADMKIMDAADYEVSQAIKFGADVITILGVAEDASIKAAIEEAHKN
                     NKQLLVDMIAVQDLEKRAKELDEMGADYIAVHTGYDLQAEGQSPLESLRTVKSVIKNS
                     KVAVAGGIKPDTIKEIVAESPDLVIVGGGIANADDPVEAAKQCRAAIEGK"
     gene            complement(2341..3099)
                     /gene="nagB"
                     /locus_tag="RPH49_002273"
     CDS             complement(2341..3099)
                     /gene="nagB"
                     /locus_tag="RPH49_002273"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDY5125394.1"
                     /translation="MKVLNLGSKKQASFYVACELYKEMAFNQHCKLGLATGGTMTDLY
                     EQLVKLLNKNQLNVDNVSTFNLDEYVGLTASHPQSYHYYMDDMLFKQYPYFNRKNIHI
                     PNGDADDMNAEASKYNDVLEQQGQRDIQILGIGENGHIGFNEPGTPFDSVTHIVDLTE
                     STIKANSRYFKNEDDVPKQAISMGLANILQAKRIILLAFGEKKRAAITHLLNQEISVD
                     VPATLLHKHPNVEIYLDDEACPKNVAKIHVDEMD"
     gene            3375..3737
                     /locus_tag="RPH49_002274"
     CDS             3375..3737
                     /locus_tag="RPH49_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YojF family protein"
                     /protein_id="HDY5125395.1"
                     /translation="MLEPIKEQEVIDLLASFEHKPVYLHVETTNGAYANHFDQRVFNA
                     GTFLRNIQITYTHAQLKGGNKEPYRIGLKLSNGGWVYVQGLTHFEVNEHDEFLIAGFN
                     YEGQLAAALQISERPFNL"
     gene            3751..4416
                     /gene="bshB2"
                     /locus_tag="RPH49_002275"
     CDS             3751..4416
                     /gene="bshB2"
                     /locus_tag="RPH49_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacillithiol biosynthesis deacetylase BshB2"
                     /protein_id="HDY5125396.1"
                     /translation="MTDERHVLVIFPHPDDETFSSAGTLASYIQKGIPVTYACLTLGQ
                     MGRNLGNPPFATRESLPSIRERELEEACKVIGITDLRKMGLRDKTVEFEPYEHIDGMI
                     KSLIDDTNPSLIISFYPGYAVHPDHEATADAVIRTVERMPKEERPRLTLVAFSNDATE
                     ALGEPDIQNDITDFKELKIKAFEAHASQTGPFLKQLASPEIDGKQHSFLTVEPYWTYH
                     FKS"
     gene            4429..5307
                     /locus_tag="RPH49_002276"
     CDS             4429..5307
                     /locus_tag="RPH49_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002445753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE2"
                     /protein_id="HDY5125397.1"
                     /translation="MTEFDLSTREGRWKHFGSVDPIEGTKPTTKNEMTDLQSTHKDFL
                     FEIEEVGIKNLVYPVLVDQYQTAGTFSFSTSLTKDEKGINMSRIIESVEKHYDNGIEL
                     EFNTLYQVLRTLQTNMKQNAAGVDVSGKWFFDRYSPTTNIKAVGNADVTYGLAIDGDK
                     VTRKELTIEATVTTLCPCSKEISEYSAHNQRGVVTVKTYINKDQDIVDDYKNKILDAM
                     EANASSILYPILKRPDEKRVTERAYENPRFVEDLIRLIAADLVEFDWLDGFDIECRNE
                     ESIHQHDAFAKLKYRK"
     gene            5589..7079
                     /locus_tag="RPH49_002277"
     CDS             5589..7079
                     /locus_tag="RPH49_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDY5125398.1"
                     /translation="MNYFVGNSLGVNLTGIEKAIINRLNLFKEMGRPAQCVFLSWNRY
                     LYRNAQNYITSSDYINMYDFFQEATYLERNEPFDWLSYWTDECHYTLKHVENSHDFRI
                     YDQERFLMYAHFQDPKYRILDYVNHFDSQRRKVKRDFYDVRGFLSCSRILVDKQQTLC
                     EFFYNPEGDTKLEKYFSYKDGKPEVQKIIVYYANKQYFFNNETELGAFFIKQLYQHGD
                     LFFSDRNVYTAPIFNLTPESIPVVAVLHSTHIKNIDALDSSPFKNVYKAMFENLSRYR
                     AIIVSTEQQKLDVEKRINRTIPVVNIPVGYSETIDTPVQTLDQRSVKLISVARYSPEK
                     QLHQQIELIKRLVSYVPKIELHMYGFGSESKKLNELIQKYGLENHVYLRGFLSNLDQE
                     YSDAYLSLITSNMEGFSLALLESLAHGVPVISYDIKYGPNELITPDFNGYLITKNDED
                     ALFDKVKYVIDHPEVQQRLSKGSLAKAQQYSKASLIKQWDQFVRLI"
     gene            complement(7205..8677)
                     /locus_tag="RPH49_002278"
     CDS             complement(7205..8677)
                     /locus_tag="RPH49_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDY5125399.1"
                     /translation="MNYILGTILESKITGVEKAQINRLKLFKQHGISSKCVYVKWNPY
                     SYTYAKQHQIENDVFTMYDYFQKAINYKKTKQVNWIQYWEKSCRYTLKFVENSNDVRI
                     YDEEQFVMYAHFLDKQYHHLNYVNYFDHKRRKVKRELYDGRGFLSCSRILGEGQRIVL
                     ENYYTPNGEIVIQKYFDDIKGKNTLTKVILNEDQHQQFFDTEDELVQYFLHQLCKNND
                     QIILDRPHELGNVIAGLNQSIPVIVVLHSTHLADTGNGIKSFYKTVFNNLTRYKAIVV
                     STEQQCQDISQYIENKIPVINIPVGYVANLKYQFDINQKEKNHIISIARLVENKQIKH
                     QVEVIKQLVTKHPNIQLNIYGHGNGLSEYRQLVEDYHLSEHVKFHGFKTHINEEIAKA
                     ELMLSTSKMEGFGLAILESLSVGTPVISYDVDYGPSELIQDGFNGYLVPQGDINQMVE
                     KVDQLLNNTQKLQQFSINSIESAQQYNATTISTKWQNILN"
     gene            complement(8796..12215)
                     /gene="sdrE"
                     /locus_tag="RPH49_002279"
     CDS             complement(8796..12215)
                     /gene="sdrE"
                     /locus_tag="RPH49_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrE"
                     /protein_id="HDY5125400.1"
                     /translation="MISNRLNKFSIRKYTVGTASILVGTTLIFGLGNQEAKAAENTST
                     ENAKQDDATTSDNKEVVSEAENNSTTENDSTNPIKKETNTDSQPEAKEESTTSSTQQQ
                     QNNVTATTETKPQNIEKENVKPSTDKTATEDTSVILEEKKAPNNTNNDVTTKPSTSEI
                     QTKPTTPQESTNIENSQPQPTPSKVDNQVTDATNPKEPVNVSKEELKNNPEKLKELVR
                     NDSNTDHSTKPVATAPTSVAPKRVNAKMRFAVAQPAAVASNNVNDLIKVTKQTIKVGD
                     GKDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTINYDKNVIPSDLTDKNDPIDITDPS
                     GEVIAKGTFDKATKQITYTFTDYVDKYEDIKSRLTLYSYIDKKTVPNETSLNLTFATA
                     GKETSQNVTVDYQDPMVHGDSNIQSIFTKLDEDKQTIEQQIYVNPLKKSATNTKVDIA
                     GSQVDDYGNIKLGNGSTIIDQNTEIKVYKVNSDQQLPQSNRIYDFSQYEDVTSQFDNK
                     KSFSNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDKYGYYNYAGYS
                     NFIVTSNDSGGGDGTVKPEEKLYKIGDYVWEDVDKDGVQGTDSKEKPMANVLVTLTYP
                     DGTTKSVRTDANGHYEFGGLKDGETYTVKFETPAGYLPTKENGTTDGEKDSNGSSVTV
                     KINGKDDMSLDTGFYKEPKYNLGDYVWEDTNKDGIQDANEPGIKDVKVTLKDSTGKVI
                     GTTTTDASGKYKFTDLDNGNYTVEFETPAGYTPTVKNTTAEDKDSNGLTTTGVIKDAD
                     NMTLDSGFYKTPKYSLGDYVWYDSNKDGKQDSTEKGIKDVTVTLQNEKGEVIGTTKTD
                     ENGKYRFDNLDSGKYKVIFEKPAGLTQTVTNTTEDDKDADGGEVDVTITDHDDFTLDN
                     GYFEEDTSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGKHTPVKP
                     MSTTKDHHNKAKALPETGSENNGSNNATLFGGLFAALGSLLLFGRRKKQNK"
BASE COUNT         3716 a         2122 c         1915 g         4496 t
ORIGIN      
        1 cttaaatcat cgaacgatta actttttgga attataacta aaaatagcga tagcacacaa
       61 cttcatgtaa gtcatatgct atcgccattt tcgacatcat atttaaatgt ttatattcga
      121 tttacttcaa taactttgtc tttactttaa tttatttgta caaaaataaa tgatcaacga
      181 atcagacatc actctttaaa aattcatgat gtttaataaa tatttatttt aaattcctaa
      241 tctaaagcga aatatttcta tgtataatct aatatttatg aatatacatt ttaaccatgg
      301 tattctctgt tttaacaaat tttataatac tgtattaatt tctgatggat cattgattat
      361 aaaatctgga tttgaatgaa gtaatgacct tgcatcatgt actccccatg ttactgctgc
      421 agatggtaca ccagcatgtt gcgccatctc aacatcaaat gttgaatcac caatataaac
      481 cgtttgttgg ctatttaaat tgtagcgttg cacaattgtg tgtatgcctt cagggtttgg
      541 tttatatgca cttacttgat cggatccaac agcttcggta atcaagtgat ttaatccaat
      601 agccgataaa tttctttcta atacatcact cttcttacta gacaccacga aaagtttttt
      661 cccttggtta tacaaacttg taatggcttc agttataccc gcaaattcat aaatatagtc
      721 cttttcaata gattgatatg tatgtctaaa tgtatcgatt aactttgcta atgctacttc
      781 atctaatggt cggtctgcta attttaaaaa tgattcttca ataggtattc ccatataatg
      841 cgttatttct ttagatgatg gttccgttaa gccacatgct ttaaatgcac tttgtgttgc
      901 tacttcacca cattttttcg tgtctgccaa cgtaccatca aaatcaaaaa tataattgtc
      961 aaacttcaat attaacaccc ctattcgttt attattgata ttatactata atttattatt
     1021 taaataaaaa aataatcgat aatatttctg cctaggcctc atattatcga ctatctttgt
     1081 tttattctaa attagcatga ttttgttgca tcgtttgttc cgttacattc atttcagtca
     1141 tcaatcccat tacaacacta tctaaaaata attgagatgc ttgttcaaac aaacttccta
     1201 atggttgtgc cgagccttgt tcatcatatt ttgtacctgc aggcaaaacg atgttcgtcc
     1261 cagctagatt gcctattgca gaatctttat ttgtagtaat taatacgatg tcagcaccta
     1321 ctgattttgc tttgtctgct aataatctta aatgttccgt ggaacctgaa ccagagataa
     1381 ttacaaatac atcattcgac ttaatcgcag gtgtcgttga ttctccaaca acatgtgcct
     1441 gtttgccgag ctgatttaag cgcattgcaa agctattcgc cacgaatcct gaacgtcctt
     1501 tgccagctac aaatatatgt ttagcatgta gtattttgga cgcaaacgtt gaaaattcat
     1561 ccgcttcaac atgtgacaaa gtcatcttta attcatctag aattaattga tagtcactaa
     1621 attcagccat attacttacc ttcgattgca gcgcgacatt gttttgcagc ttctactgga
     1681 tcatctgcat ttgcgattcc gccaccaaca ataacaagat caggactttc agcgacaatt
     1741 tctttaattg tatctggttt aattccacct gctactgcaa ctttagaatt tttaataaca
     1801 gatttaacgg ttcttaaact ttctaatggt gattgccctt ctgcttgtaa atcataacca
     1861 gtgtgtactg caatataatc cgcacccatt tcatctagtt cttttgcacg tttttctaaa
     1921 tcttgaacag caatcatatc aactagtaat tgtttattat ttttatgagc ttcttcaata
     1981 gctgctttaa ttgatgcatc ttctgcaaca cctagtattg taattacatc cgcgccaaat
     2041 ttaattgctt ggctaacttc ataatcagct gcatccataa ttttcatgtc tgctaatact
     2101 tttacattac taatgttgtc tgccatatgt ttaactgctg gtaaaccttc gttgtaaatg
     2161 attggcgtac cgatttctac gatatctaca taatctttta ctttatttgc taactcagcc
     2221 gcgtcttctt tgtttaataa atcaattgct aattgtaatt ccactaaaaa tcatccttcc
     2281 aatgcttttt atctttctat tggaaccttt cccgaggcat ttcttaatta aacattgcaa
     2341 tcaatccatt tcatcgacat gaattttcgc aacatttttc gggcaagctt cgtcgtctaa
     2401 atatatctca acattcgggt gtttgtgaag taatgtggct ggaacatcaa cagaaatttc
     2461 ctgatttaat aaatgtgtaa tagcagcacg tttcttttca ccaaatgcga gtaaaatgat
     2521 acgtttggct tgaagaatat tagcaagtcc catcgaaatg gcttgctttg gaacatcatc
     2581 ttcgttttta aaatatcgac tattagcctt aatagtactt tcagtcaaat caacgatatg
     2641 agtaacgcta tcaaacggcg taccaggttc attaaatcca atatgaccat tttctccaat
     2701 acctaaaatt tgaatatcac gttgaccttg ttgttctaaa acgtcattat attttgacgc
     2761 ttccgcattc atatcatcgg catctccatt tggaatatga atgttctttc tattaaaata
     2821 aggatattgt ttgaaaagca tgtcatccat ataatagtga taactttgcg gatgtgatgc
     2881 ggttaaacct acatattcgt ctaaattaaa cgtggataca ttatctacgt ttaactgatt
     2941 tttatttaat aacttaacaa gttgttcata caaatctgtc attgtaccac cagttgctaa
     3001 acctagttta cagtgctgat taaatgccat ctctttatat aactcacatg caacatagaa
     3061 tgatgcttgt tttttcgatc ctaagtttaa tactttcatt gtttacatgc ctccacaaat
     3121 ttaatacatt ttaaaaactt atgaattcat tcatacacca ttaatatagc atcattttta
     3181 atgtttaaca cttttcaaat tccaacaaat ttttgatttt taaaagtaaa aaacgaatgc
     3241 tgtatgatta cgtaatcctg agtaattacc cttcatgaaa attaatttat aaataattga
     3301 gcaatcgtat acaattatcg aatagttttt agtaaaatag aaagataaac acattgatag
     3361 tgtaaggagt gaacgtgttg gaaccaatta aagaacaaga agttatagat ttacttgctt
     3421 cttttgaaca taaacctgtg tatctgcatg ttgaaacgac aaatggggcc tatgcgaacc
     3481 atttcgatca acgtgttttt aatgctggta cttttttaag aaacatacaa ataacatata
     3541 cgcatgcaca actaaaaggt ggtaataaag aaccttatcg cattggtctt aaactatcaa
     3601 atggtggttg ggtttatgta caaggtctaa cgcattttga ggtcaatgaa catgatgaat
     3661 ttttaattgc aggttttaat tacgaaggtc aactcgctgc agcacttcaa attagtgagc
     3721 gaccatttaa tttatagagg aggcatcaac atgactgacg aaagacatgt attagtaata
     3781 tttccacatc ctgatgatga aaccttctca tctgcaggca cattagcaag ttatatccaa
     3841 aaaggcatac ctgtaacata tgcatgttta accctaggac aaatgggcag aaatttaggt
     3901 aatcccccat ttgcaacacg cgaatcatta ccaagtattc gtgagcgtga actagaagaa
     3961 gcttgtaaag ttattggtat tactgattta agaaaaatgg gtttacgtga caaaactgtc
     4021 gaatttgaac cctacgaaca tatagatggt atgattaaat ctttaatcga tgatacaaat
     4081 ccatcattga ttatttcatt ttatcctgga tatgcagtac atcctgatca cgaagcaaca
     4141 gcagacgctg taattcgaac ggttgaacgc atgcctaaag aagaacgccc tcgtttaact
     4201 ttagttgcgt tcagtaatga tgcaaccgaa gctcttggag aacctgatat tcaaaatgat
     4261 attacagatt ttaaagaact taaaattaag gcatttgaag cacatgcttc tcaaacaggt
     4321 ccatttttaa aacaattagc aagtcctgaa atcgatggta aacaacacag ctttttaaca
     4381 gtcgaaccat attggacata tcactttaaa tcttaacgga ggaaaaaaat gactgaattt
     4441 gatttatcga cacgagaagg tcgttggaaa cactttggtt ccgtagatcc tattgaaggc
     4501 acgaaaccta ctactaagaa cgaaatgaca gacttacaaa gtacacataa agatttttta
     4561 tttgaaatag aagaagttgg tattaaaaac ttagtgtacc ctgtacttgt tgaccagtat
     4621 caaacagctg gcacatttag tttttcaaca agtttaacaa aagacgaaaa aggtattaat
     4681 atgagccgta taattgaaag tgttgaaaag cactatgata atggtattga acttgaattt
     4741 aatacacttt atcaggtgtt acgcacttta caaacgaata tgaaacaaaa tgcggcaggc
     4801 gttgatgttt ctgggaaatg gttctttgat cgctatagtc caaccacaaa tattaaagca
     4861 gttggtaatg ccgatgtcac ttatggatta gcaattgacg gtgataaagt tacacgtaaa
     4921 gaacttacta ttgaagcaac tgtcacaacg ctatgccctt gttcaaaaga aataagtgag
     4981 tattcagcgc acaaccaacg tggtgttgtc actgttaaaa catatattaa taaagatcaa
     5041 gacatagttg atgactataa aaataaaatt ttagatgcaa tggaagctaa tgcaagttca
     5101 attctatacc ctattttaaa acgtcctgat gaaaaacgtg tgacagagcg tgcatatgaa
     5161 aatccacgtt ttgtcgaaga cttaattcgt ttaattgccg cggacttagt tgaatttgat
     5221 tggttagacg gtttcgatat cgaatgtcgt aatgaagagt ctatccatca acatgatgct
     5281 ttcgctaaat taaagtatcg caaataatat catatgatta attcaaacgc gtaacagtag
     5341 ttgcgcgttt ttattatacc ttctagagtt gtatatctct tttataaatc ttctcatttg
     5401 atgtgcctga gtcataaatc aatttcctaa actctacaat gatatattgg tcgtagttga
     5461 ctgaataact actaccatta taaatatcaa aacttgttgt tttataaata aacacatctt
     5521 ccagttaaaa gaagtaatta aatattatgt gatataatta taaaaaatag atataagtgg
     5581 tgttgtaaat gaattatttt gtaggtaata gtttaggtgt taatttaact gggatagaga
     5641 aagcaattat taatcgttta aatttattta aagaaatggg aagaccagcg caatgtgtat
     5701 ttctgtcatg gaatagatat ttatatagaa atgcccaaaa ttatattact agttctgact
     5761 atattaatat gtatgatttc ttccaagaag caacatattt agaacgcaat gaaccatttg
     5821 actggttgtc gtattggact gatgaatgtc attatacttt aaaacatgtt gaaaatagtc
     5881 atgactttag aatatatgat caagagcgtt tcttaatgta tgcccatttt caagatccta
     5941 aatatcgtat attagattat gtgaatcatt ttgatagtca aagacgaaaa gtaaaacgtg
     6001 atttttatga tgtgcgtggc tttttaagtt gtagtaggat tcttgttgat aaacaacaaa
     6061 cattatgtga atttttctat aatccagaag gtgacacaaa attagaaaag tatttttctt
     6121 acaaagatgg caaaccagaa gtacaaaaaa ttattgttta ctatgctaac aaacaatatt
     6181 tctttaataa tgaaacggaa ttaggcgcat ttttcattaa acaactatat caacatgggg
     6241 atttattttt cagtgaccgt aatgtgtaca cagcacctat tttcaactta acgcctgagt
     6301 caatcccagt agtagctgtg cttcacagta cacacattaa aaatattgat gcattagatt
     6361 catcgccatt taaaaatgta tataaagcga tgtttgaaaa tttatctcga tatcgtgcaa
     6421 ttatcgtttc tactgagcag caaaaattag atgttgaaaa acgtattaac cgtactattc
     6481 cagttgttaa tattcctgtc ggctatagtg aaacaattga tacaccagtc caaacattag
     6541 atcagcgcag tgttaaatta atttccgttg ctcgttattc acctgaaaaa caattacatc
     6601 aacaaattga attaattaaa cgcttagtat cgtatgtccc aaaaatagag cttcatatgt
     6661 atggttttgg ttctgaaagt aaaaaattaa atgaattgat acaaaaatat ggattggaaa
     6721 atcatgttta cttacgcggc tttttaagca atctagacca agaatatagc gatgcctatt
     6781 tgagtttaat aacaagtaac atggaaggtt tctctttagc gctacttgaa tctttagcac
     6841 atggtgttcc agttattagt tatgatatta aatatggacc taacgaatta attacgcctg
     6901 atttcaatgg ttatttaatt actaaaaatg atgaagatgc cctatttgat aaagtaaaat
     6961 atgtgattga tcatcctgaa gtacagcaac gactgtcaaa aggtagtttg gcaaaagcgc
     7021 aacaatatag taaagcgtcg ttaattaaac aatgggacca atttgttcgt cttatataaa
     7081 tgtacttcac ctttattttt ataaaaaaaa agcgttttcc tatgtcattt aactaaacat
     7141 gtaagttcgt atgaacgttg tttgttaaat agatgattct aggaaaatgc ttttttcttt
     7201 tgacttagtt taaaatattt tgccactttg tactgatagt agttgcattg tactgttgtg
     7261 cagattctat gctattaatc gaaaactgtt gcaatttttg agtattattt agtaattggt
     7321 cgaccttttc aaccatttga ttgatgtcac cttgaggtac taaatagcca ttaaatccat
     7381 cttgaatcag ttctgatgga ccataatcta catcataact gatcactggt gtacctactg
     7441 aaagcgactc taaaattgct aagccaaaac cttccatttt acttgtcgat aacatcagtt
     7501 ctgctttagc aatctcttca ttaatatgcg tcttaaaacc atgaaatttt acatgttccg
     7561 ataaatgata atcttctaca agttgtcgat attctgacaa accatttcca tgtccataaa
     7621 tatttaattg aatattggga tgttttgtta ctaattgctt gatcacttca acttgatgtt
     7681 taatttgttt attttcaacg aggcgagcaa ttgatatgat atgatttttc tccttttgat
     7741 tgatgtcaaa ttgatacttt aaatttgcca cgtagccaac cggaatattg ataactggta
     7801 ttttattttc aatatattgt gaaatatctt ggcattgctg ttctgttgat acaacaatcg
     7861 ctttataacg tgttaaatta ttaaacactg ttttataaaa actttttata ccattaccgg
     7921 tgtcggctaa atgtgtactg tggagcacaa caataactgg aatactttga tttaatcccg
     7981 ctataacatt tcctaattca tgaggacgat ctaatatgat ttgatcatta tttttacata
     8041 attgatggag aaaatattga actaattcat cttctgtatc aaaaaattgt tgatgctgat
     8101 cttcatttaa gataaccttt gtgagcgtgt ttttcccttt tatatcgtcg aaatattttt
     8161 ggatgacgat ttccccatta ggtgtatagt aattttcgag tacaatccgt tgtccttcac
     8221 ctaaaattcg agaacaactt aaaaagcctc ttccatcata caattcgcgt tttacttttc
     8281 ttcttttatg atcaaaataa ttcacatagt ttaaatgatg atactgttta tctaaaaaat
     8341 gtgcatacat tacaaattgc tcttcatcat atattctgac atcatttgaa ttttccacaa
     8401 atttcaatgt gtacctacat gacttttccc aatactgtat ccagttaact tgctttgtct
     8461 ttttataatt gattgctttt tgaaaatagt catacattgt aaatacatca ttttcaatct
     8521 gatgttgctt cgcatatgtg tatgaataag gattccattt aacatataca cattttgaag
     8581 atatgccgtg ttgtttgaac aacttcaatc tatttatttg cgctttttct acacctgtaa
     8641 ttttactttc taaaattgtt cctaaaatgt aattcatatt atcgcctcat ataagtttta
     8701 ttccgtatct ttattgttta ttttatatga aaaatacatc tattgcatgt gtaattataa
     8761 aaaaaccagg ccacaaggac ctgggtcata ttgtattatt tgttttgttt tttgcgacga
     8821 ccgaataaca ataatgaacc taatgctgca aataatccac caaataacgt tgcgttattt
     8881 gagccgttat tttcactacc tgtttctggt aatgcttttg ctttattgtg atggtcttta
     8941 gtagtactca ttggtttaac aggtgtatgt tttcctgcat ccgagtccga atcgctatct
     9001 gagtctgagt cgctgtccga atctgagtcg ctatctgagt ctgagtcgct gtccgaatct
     9061 gagtcgctgt ctgaatctga gtcgctatct gagtctgaat cactgtccga atctgagtcg
     9121 ctatctgagt ctgagtcgct atctgaatct gaatcgctgt ctgagtctga gtcactgtct
     9181 gagtctgagt cgctatctga gtctgagtca ctgtctgaat ctgagtcgct atctgagtct
     9241 gaatcgctgt ctgaatctga gtcgctatct gagtctgaat cgctgtccga atctgagtcg
     9301 ctatctgagt ctgagtcgct atctgaatct gaatcactat ctgagtctga gtcgctgtct
     9361 gaatctgaat cgctgtctga gtctgaatcg ctatctgagt ctgaatcgct atctgagtct
     9421 gaatcgctgt ctgagtctga atcactgtct gatgtatctt cttcgaagta tccgttatca
     9481 agtgtgaaat catcatgatc cgtaattgtt acgtcaactt cgccaccatc tgcatcttta
     9541 tcatcttcag ttgtatttgt aactgtttgt gttaagccag caggcttttc aaaaataact
     9601 ttgtatttac cgctatctaa attatcgaaa cgatatttac cattttcatc tgttttagtt
     9661 gttccaatta cttcgccttt ttcgttttgc aatgtaactg tcacatcttt aatacctttt
     9721 tcagttgagt cttgtttgcc gtctttgtta ctgtcgtacc aaacataatc acctaaactg
     9781 tattttggtg ttttatagaa accactgtct aatgtcatat tatctgcatc tttaatgaca
     9841 cctgttgttg ttaaaccatt agaatcttta tcttcagctg tagtattttt aaccgttggc
     9901 gtgtaacctg ctggtgtttc aaattctact gtatagttac cattatctaa atctgtaaat
     9961 ttatatttac ccgaggcatc agtagtagtt gtaccaataa cttttccagt actatctttc
    10021 aatgtaacct tgacatcttt gataccaggt tcattagcat cttggatacc atctttattt
    10081 gtatcttccc atacatagtc accaagatta tatttaggtt ctttataaaa accagtgtct
    10141 aaagacatat catctttacc attaatttta acagttacag aactaccatt tgagtctttt
    10201 tcaccatcag ttgttccatt ttcttttgtt ggaaggtatc cagctggcgt ttcgaattta
    10261 actgtataag tttctccgtc tttcaaacca ccgaattcat aatgaccatt cgcatctgtt
    10321 cttactgatt ttgtagtacc gtccgggtaa gttaatgtaa ctaaaacgtt tgccattggc
    10381 ttttcttttg aatctgtacc ttgaacaccg tctttatcaa cgtcttccca tacatagtca
    10441 ccaattttgt ataacttttc ttcaggttta acagtaccgt caccaccgcc agagtcatta
    10501 gaagttacga tgaagtttga atatcctgca taattataat aaccatattt atcagttgtt
    10561 ctcatactag taccttgggc aatatctagt tcgccatctg atgtaggtgt atatttacta
    10621 acaactttga taatataggc tgaattaata tcaccaaaat ccaatgttgc tacattatta
    10681 ctaaatgatt ttttattatc aaattgactt gttacatctt cgtattgact aaaatcatag
    10741 attctattac tttgaggcaa ttgttgatca gagttaactt tataaacctt tatttctgta
    10801 ttttggtcaa taatggtact accatttcct agtttaatat ttccataatc atctacttga
    10861 ctaccagcta tatcaacttt agtgttggtt gctgattttt tcaatgggtt aacataaatt
    10921 tgttgttcaa tagtttgctt atcttcatct aattttgtaa agatagattg aatgtttgaa
    10981 tcaccatgga ccattggatc ttgataatca acagtgacat tttggcttgt ttctttacct
    11041 gctgtagcaa atgttaaatt caaacttgtc tcatttggaa ctgttttttt atcaatatac
    11101 gaatatagag ttaagcgtga ttttatatct tcatatttat ctacatagtc tgtaaatgta
    11161 tatgtgattt gcttagttgc tttatcaaat gttcctttag caatgacctc tcctgatgga
    11221 tcagtaatat cgataggatc atttttatct gttaaatccg aaggaattac attcttatca
    11281 taattaatcg tcattgtatc gccttttttg actttattgt caattgtaaa ctctgtatca
    11341 tattcaatat ctttaccgtc atgcgctgct gccacattat ctttaccatc gccaactttg
    11401 attgtttgct tcgtcacttt aattaaatca tttacattgt ttgaagcaac tgctgctggt
    11461 tgtgcaactg caaagcgcat ttttgcgttt acacgttttg gtgcaacact tgttggagct
    11521 gtagcaactg gtttagttga atgatctgta ttgctatcat ttctaaccaa ttcttttaat
    11581 ttctcaggat tatttttaag ttcttctttt gacacattta ctggttcttt tggattagtt
    11641 gcatctgtaa cttgattgtc tacttttgaa ggcgttggtt gcggttgtga attttcaata
    11701 tttgtagatt cttgaggtgt agttggtttt gtttgaattt cacttgtaga tggttttgta
    11761 gttacatcgt tatttgtatt atttggtgct ttcttctctt ctaaaataac agatgtatct
    11821 tctgtcgcgg ttttatcagt tgaaggttta acattttctt tttcaatgtt ttgaggctta
    11881 gtttcagttg tagctgtaac gttattttgc tgttgttgag tacttgatgt agttgattct
    11941 tctttagctt ctggttgtga atcagtattt gtttctttct taattggatt tgttgaatca
    12001 ttttctgttg tcgaattatt ttcagcttct gacactactt ctttattatc actagtcgtt
    12061 gcatcatctt gttttgcatt ttctgtacta gtgttttcag cagctttagc ttcttggttc
    12121 cctagaccaa aaatcaatgt cgtacctact aaaatcgatg cagttcctac agtatacttt
    12181 ctaatcgaaa atttgtttaa gcgatttgaa atcataccct tttttgttat tgccttttta
    12241 ttatccctg
//
LOCUS       DAPSKH010000069        11974 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPSKH010000069 DAPSKH010000000
VERSION     DAPSKH010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 11974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11974
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.069"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(115..264)
                     /gene="rpmG"
                     /locus_tag="RPH49_002280"
     CDS             complement(115..264)
                     /gene="rpmG"
                     /locus_tag="RPH49_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDY5125401.1"
                     /translation="MRVNVTLACTECGDRNYITTKNKRNNPERIEMKKYCPRLNKYTL
                     HRETK"
     gene            complement(355..1872)
                     /locus_tag="RPH49_002281"
     CDS             complement(355..1872)
                     /locus_tag="RPH49_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase"
                     /protein_id="HDY5125402.1"
                     /translation="MSQQDKKLTGVFGHPVSDRENSMTAGPRGPLLMQDIYFLEQMSQ
                     FDREVIPERRMHAKGSGAFGTFTVTKDITKYTNAKIFSEIGKQTEMFARFSTVAGERG
                     AADAERDIRGFALKFYTEEGNWDLVGNNTPVFFFRDPKLFVSLNRAVKRDPRTNMRDA
                     QNNWDFWTGLPEALHQVTILMSDRGIPKDLRHMHGFGSHTYSMYNDSGERVWVKFHFR
                     TQQGIENLTDEEAAEIIATDRDSSQRDLFEAIEKGDYPKWTMYIQVMTEEQAKNHKDN
                     PFDLTKVWYHDEYPLIEVGEFELNRNPDNYFMDVEQAAFAPTNIIPGLDFSPDKMLQG
                     RLFSYGDAQRYRLGVNHWQIPVNQPKGVGIENICPFSRDGQMRVVDNNQGGGTHYYPN
                     NHGKFDSQPEYKKPPFPTDGYGYEYNQRQDDDNYFEQPGKLFRLQSEDAKERIFTNTA
                     NAMEGVTDDVKRRHIRHCYKADPEYGKGVAKALGIDINSIDLETENDETYENFEK"
     gene            2076..3530
                     /locus_tag="RPH49_002282"
     CDS             2076..3530
                     /locus_tag="RPH49_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDY5125403.1"
                     /translation="MEDNKMNRSLNSRHISMIAIGGAIGTGLFVATGNIISQAGPGGA
                     ILAYLVIGVMLYFLMSSIGELATFYPVSGSFSSYSTRFIDSSLGFTMGWLYWALWSLV
                     TSVDVIVASNVLYFWDTFKFFHPITWSLIFITILLLLNIFSVKSFGETEFWLSLIKVL
                     TIIVFVIFGFLMIFGILGGHAYGFENYTKGQAPFVGGISGFLGVLLVAGFSVGGTEVV
                     AVTAGESDDPKKSMPKAIKQVFWRILLFYVLSIAVIGAIIPYTDPSLLRASSSISQSP
                     FTIVFDRVGIAFAASVINAVILTSLLSAANSGVYTTGRMLYSLSSDKKAPQFLSKLNK
                     TTKLPLRALLTTYAVVVIVIIYANFNSNAVFNLLEIIGSMIIVVWGSSIWSQIRLRQA
                     IKKQGQDPNKVLPYKAPFYPLGPIIVITTLLFLLFGGSVEYILKDQWLNAFKNFLPLI
                     ILVSIYFIHKIIHKTKFVKLETINLKPHDYDNQK"
     gene            3670..3774
                     /locus_tag="RPH49_002283"
     CDS             3670..3774
                     /locus_tag="RPH49_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125404.1"
                     /translation="MLPFFILDILHIVYNIDNNNFSGVKFNDWTNKFI"
     gene            3749..4063
                     /locus_tag="RPH49_002284"
     CDS             3749..4063
                     /locus_tag="RPH49_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125405.1"
                     /translation="MIGQTNLFDDVLKQDERFVIVVQALEEKNGQLLKRTLREYPGLN
                     HKQMNDLFTHLKELFSEESFAENQSAFSITVYTNLDYTADQIYAHVKRFRGKHDWTQT
                     AK"
     gene            complement(4392..5195)
                     /locus_tag="RPH49_002285"
     CDS             complement(4392..5195)
                     /locus_tag="RPH49_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDY5125406.1"
                     /translation="MTNYKVVVLDMDDTLLNSDNVISEETANYLTAIQDEGYYVVLAS
                     GRPTEGMIPTARDLKLPEHHSYIISYNGSKTINMTNEEVEVSKSIGKQDFDEIVDYCR
                     DRGFFVLTYHDGQIIYDSEHEYMNIEAELTGLPMKRVDDIKAYIQGDVPKVMGVDYVA
                     NITEARIDLNGVFNDNVDATTSKPFFLEFMAKDVSKGNAIKALCHKLGYSVDQVIAFG
                     DSMNDKSMFEVAGLAIAMGNASDELKQYADEVTLDHNENGIPHALKKLL"
     gene            complement(5253..6167)
                     /locus_tag="RPH49_002286"
     CDS             complement(5253..6167)
                     /locus_tag="RPH49_002286"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDY5125407.1"
                     /translation="MSNVLELTIPASTANLGVGFDSIGMALDKFLHLSVKETSGTKWK
                     YIFHDDASKQLPTDETNFIYHVAQQVASKYSVDLPNLCIEMRSDIPLARGLGSSASAL
                     VGAIYIANYFGDIQLSKHEVLQLATEIEGHPDNVAPTIYGGLIAGYYNDVSKETSVAH
                     IDIPDVDVIVTIPTYELKTEASRRALPQKLTHSEAVKSSAISNTMICALAQHNYELAG
                     KLMQQDGFHEPYRQHLIAEFDEVKTIASQHNAYATVISGAGPTILIFSRKENSGELVR
                     ALNRNVVTCHSELVDINVSGVKERIVYQ"
     gene            complement(6169..7230)
                     /locus_tag="RPH49_002287"
     CDS             complement(6169..7230)
                     /locus_tag="RPH49_002287"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDY5125408.1"
                     /translation="MRRWQGLVEEFKAHLPVNENTPKLTLNEGNTPLIHCENMSKILG
                     IDLYVKYEGANPTGSFKDRGMVMAVTKAKEQGKKIVICASTGNTSASAAAYAARAGLK
                     AIVVIPEGKIALGKLSQAVMYGAEIVSIEGNFDEALEIVKEIAKSGEIELVNSVNPFR
                     IEGQKTGSFEIVQQLDGEAPDILAIPVGNAGNITAYWKGFKEYHEAKGSQLPKMFGFQ
                     AEGASPIVQNKVIKNPETIATAIRIGNPASWDKATNALKESNGLIDSVTDDEILEAYQ
                     LMTTKEGVFSEPASNASIAGLIKLHRQGKLPQGKKVVAILTGNGLKDPDTAISLLDNP
                     IKPLPNDKDSIIDYIKGAL"
     gene            complement(7236..8516)
                     /locus_tag="RPH49_002288"
     CDS             complement(7236..8516)
                     /locus_tag="RPH49_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HDY5125409.1"
                     /translation="MKKLNIALLGLGTVGSGVVKIIEENRQQIQDTLNKDIVIKHILV
                     RDKSKKRPLNISQYHLTEDVNEILNDDSLDIIVEVMGGIEPTVDWLRTALKNKKHVIT
                     ANKDLLAVHLKLLEDLAEENGVALKFEASVAGGIPIVNAINNGLNANNISKFMGILNG
                     TSNFILSKMTKEQTTFEEALDEAKRLGFAEADPTDDVEGVDAARKVVITSYLSFNQVI
                     KLNDVKRRGISGVTLTDINVADQLGYKIKLIGKGIYENGKVNASVEPTLIDKKHQLAA
                     VEDEYNAIYVIGDAVGDTMFYGKGAGSLATGSAVVSDLLNVALFFESDLHTLPPHFEL
                     KTDKTREMMDSDAEINIKEKSNFFVVVNHVKGSIENFENELKAILPFHRSLRVANYDN
                     QSYAAVIVGLESSPEELITKHGYEVDKVYPVEGV"
     gene            8707..10089
                     /locus_tag="RPH49_002289"
     CDS             8707..10089
                     /locus_tag="RPH49_002289"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDY5125410.1"
                     /translation="MKVSKFGGSSVSNATQIKKVLNIVNSDPERKIVIVSAPGKRHDN
                     DIKTTDLLIRLYEKVINHLDYHDKKREIIQRYDDIVKELQMDESILRTIDVTLEHYIN
                     QLKNEPKRLLDALLSCGEDFNAQLIALYNNSQGIPTKYISPKEAGIFVTDVPQEAQIL
                     DSAYSEIKKLRDYEEKLIIPGFFGVSHEGYIVTFPRGGSDITGAIISSGVRATIYENF
                     TDVSGIYKANPNIIKDPELIEEITYREMRELSYAGFSVFHDEALQPLYKDRIPVVIKN
                     TNRPQDKGTFIVHDREINAKNVISGISCDKDFTVINIKKYLMNRQVGFTRKILGVLED
                     NNISFDHMPSGIDTISIVMRSKQIQNKETKVLNEIRQKCDVDELSIEHDLAILMIVGE
                     GMNKVIGTANKITHALAESKINLKMINQGASEISMMFGIHVDDAEKAVLSTYEFCYHG
                     VALKNLCDKN"
     gene            complement(10143..10718)
                     /locus_tag="RPH49_002290"
     CDS             complement(10143..10718)
                     /locus_tag="RPH49_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125411.1"
                     /translation="MNAKEQLVDNLMKTSSQLFKFHGEVAMQLFLNDELKLPSIVEIC
                     VERKRLSDIVKVIPQSYALLYIDKQDQAIAKEDLSLSKIAKVYVQYDDTTIMSIFVYD
                     VVNDEWIFRLDPNIRIPKSNIYFHSLNWDVDYIKPEIVLMYDLMQHHQYHHYSNYKRV
                     IDALSYYQFFILKFVVGEQRIKDAIQRTINN"
     gene            11049..11903
                     /locus_tag="RPH49_002291"
     CDS             11049..11903
                     /locus_tag="RPH49_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125412.1"
                     /translation="MSFYVVLIIIIVALIGILVLNQRYSNSKIDTEVYARKQLIKKNK
                     ALSAENAELRSQMLSSNNDVGHHAYKNAKRELRKILDSYLENGKLKYYDIIVTSNLAT
                     KHPFFEYARSFDFIIVSDIGLINVDVKSWGEKTFYHFDVPDEHDTEMSNSNIEKVVGH
                     YISQQYHDQFNSSRKSIYTFTETVQPNRVIYDFYDYDPYQLAANNAKALKDHIEQKFN
                     FKVQSTGVIYFSDGTVNIIQGSEERDKYVDTVSTKSSLRRIISEAIELSKHPLNKEQV
                     DQITAIFK"
BASE COUNT         3882 a         2089 c         1762 g         4241 t
ORIGIN      
        1 gatgaaactc aattcattaa tcactcttta caaaaatttc ataaaaaagc gagctcccca
       61 atataatagg taagcccgct ttattttcaa atcgtcgtat ttgaatgata agaattactt
      121 agtttcacga tgtaacgtat atttgtttaa tcttgggcaa tattttttca tttcaatacg
      181 ctcaggatta ttacgtttat ttttagtagt gatatagtta cgatcgccac attctgtgca
      241 tgctaatgtt acgtttacgc gcacgttaaa caccctctct tgttaggaat ctttacgatt
      301 tattatgata tcataaactg ctcaactacg caatatagaa actacatatc aaatttattt
      361 ttcaaagttt tcgtatgttt catcattttc agtttcaaga tcaatagaat ttatatcaat
      421 acctaatgct tttgcaacac ctttaccata ttctgggtca gctttgtaac aatgacgaat
      481 atgacgtcgt ttaacatcat ccgttacgcc ttccattgca tttgctgtat ttgtaaaaat
      541 tctttcttta gcgtcctctg attgtaatct aaacaattta cctggttgtt caaaataatt
      601 atcatcatct tgacgttgat tatattcata gccgtatcca tcagttggga atggtggctt
      661 tttatattca ggttgagaat caaatttacc atggttattt ggataataat gtgttcctcc
      721 accttggtta ttgtcaacta cacgcatttg accatctcta ctaaaaggac aaatattttc
      781 aataccaaca cctttaggtt ggtttacagg aatctgccaa tgattaactc ctaatcgata
      841 tctttgcgca tcgccatatg agaataaacg cccttgcaac attttgtctg gagaaaaatc
      901 taatcctgga ataatattag ttggtgcaaa cgcagcttgt tcaacatcca taaagtaatt
      961 atctggattt ctatttaatt caaactctcc aacttcaatt agaggatact catcgtgata
     1021 ccatactttt gttaaatcaa atggattatc tttatggttt ttagcttgtt cctcagtcat
     1081 tacttgaata tacattgtcc attttggata atcacctttt tcaatggctt cgaataaatc
     1141 gcgttgagat gaatcacgat ctgttgctat aatttcagca gcttcttcat cagttaagtt
     1201 ttcaatacct tgttgcgttc taaaatggaa tttaacccaa acacgttcac cagaatcatt
     1261 atacatagag tatgtgtgtg aaccgaaccc atgcatgtga cgtaaatctt taggaatccc
     1321 tctatctgac attaagatcg ttacttggtg caatgcttct ggaagccccg tccagaaatc
     1381 ccagttattt tgtgcatctc tcatatttgt tctaggatct cgtttcaccg cgcgatttaa
     1441 actaacaaat agctttggat ctctaaagaa gaatactggt gtgttattcc ctactaaatc
     1501 ccagtttcct tcttctgtgt agaactttaa cgcaaatcct cgaatgtcac gctccgcatc
     1561 agcagcacca cgttctcctg ctacagtaga gaaacgggca aacatttcgg tttgcttacc
     1621 tatttcagag aatattttag cattcgtata ttttgttata tctttagtta cagtaaatgt
     1681 cccaaatgca ccagaacctt tggcatgcat tcgacgttct ggtattactt ctctatcaaa
     1741 ttgggacatt tgctctaaaa agtaaatatc ttgcattaaa agaggtcccc taggccctgc
     1801 tgtcatacta ttttctcgat ctgatactgg atgcccaaaa acaccagtta actttttgtc
     1861 ttgttgtgac atagtcatcc ctccacaatt tataataatt ataatttaat acatattata
     1921 atttaacccc atcaaaatta caattaaaca tgctcaaaat gattaaaaaa tcagaaaatt
     1981 ttaatttttt cgctttacag cactaaatag ttattgaata gtacacttaa aaagcttaca
     2041 ataatgggta tatttaaata gatgggagac taaatatgga agataataaa atgaaccgta
     2101 gtcttaactc aagacacatt tccatgattg ctataggcgg tgcaattggg actggtctat
     2161 ttgtagctac tggtaatatc atttctcaag ctggtcctgg aggcgctata ctcgcttatc
     2221 ttgttattgg tgtcatgcta tatttcttaa tgtcatcaat tggagagttg gcaacatttt
     2281 atccagtatc aggttcattc agctcttatt caacacgctt tattgactca tctctaggct
     2341 ttaccatggg atggttgtat tgggcattgt ggtcattagt tacaagtgtt gatgtcatag
     2401 tagcgtcaaa tgtgctttat ttctgggaca catttaaatt tttccacccc attacttgga
     2461 gcttaatctt tattacaatt ttactattat taaacatttt ttctgtaaaa tcatttggag
     2521 aaactgagtt ttggttatca ttgattaaag tgttaacaat tatcgtattc gttatttttg
     2581 gctttttaat gattttcggt atcttaggtg gtcatgcata tggatttgaa aactatacaa
     2641 aaggccaagc accgtttgtt ggtggtatct ctggtttctt aggcgtatta ttagtcgccg
     2701 gattttcggt tggtggtaca gaagtagttg cagtaactgc tggtgaatca gatgacccta
     2761 aaaagtctat gcctaaggca attaaacaag tattttggcg tattctttta ttctatgtct
     2821 tatcaattgc agtaattggt gcaattattc cgtacacaga tccatcatta ttaagagcaa
     2881 gtagttcaat aagtcaaagc ccatttacaa ttgtattcga tagagtaggc atagcctttg
     2941 cagcatcagt aatcaacgcg gttattttaa cttcattatt atccgctgca aattcaggtg
     3001 tttatacaac aggaagaatg ttgtattcct taagttcaga caaaaaagca ccccaatttt
     3061 taagtaaatt aaacaagaca acaaagttac ctttaagagc attattaact acttatgcag
     3121 tcgttgttat tgttattatt tatgcaaact ttaattcaaa tgccgttttt aatttacttg
     3181 aaattattgg ttcaatgatt atagttgttt ggggatcaag catttggtca caaatacgat
     3241 tgcgacaagc tattaaaaaa caaggtcaag atcctaataa ggtcctacca tataaagcac
     3301 ctttttatcc attaggacca atcattgtca tcactacgct attattcttg ctatttggtg
     3361 gctcagttga atatatttta aaagatcaat ggttaaatgc ttttaaaaac tttttacctt
     3421 taatcattct agtgtcgatt tactttattc ataaaatcat tcacaaaaca aaatttgtaa
     3481 agctagaaac aattaattta aaaccacacg attatgacaa tcaaaaataa ataaattctc
     3541 acacggcaga tgctttagat tatctatagc atttgccgct ttttaatggt gtaaagcaag
     3601 atatacttta atatcttttt ctagtataaa gtgtattaac tagtattctg tttatatttt
     3661 attatgacca tgttaccatt ctttatttta gatattttgc atatcgtgta taatatagat
     3721 aacaataact tttcaggggt gaaattcaat gattggacaa acaaatttat ttgatgatgt
     3781 actaaagcaa gatgagagat ttgttattgt agttcaagca ttagaagaaa agaacggaca
     3841 attattaaaa agaactttaa gggaatatcc cggtttaaac cataaacaaa tgaatgattt
     3901 atttacgcac ttaaaggaat tattttccga agaatcattt gctgaaaacc aatcagcgtt
     3961 cagtattaca gtttatacaa atttagatta tactgctgac caaatatatg ctcatgtaaa
     4021 acgcttcaga gggaagcatg actggacaca aacagctaaa taaaatcaag atgcttgcag
     4081 tgattttaac aattaatgtt agattgtcac tgcatttttt aatacattcg tcattattca
     4141 gaatgattca aatttattta tctaccttcc gtgactaatt aatacttgat ttattaaaaa
     4201 aatatacatc tactatattc gtttgatatc attactaatc taaaatatgt atttcaaata
     4261 ctctatagta taactgaagt cattttcaca taaataaagc tcccttcaaa gctttcattt
     4321 tttcaatgtc tactttgaaa ggagcatttc aatcttattc aaatatcatg tgttaaggct
     4381 tattttaaaa tttataacaa ttttttgagc gcatgcggaa taccattttc attatgatcc
     4441 aacgtaactt catctgcata ttgcttaagt tcatctgatg cattccccat agcaatagct
     4501 agacctgcga cttcaaacat tgatttatca ttcatactat caccaaaagc aatgacttga
     4561 tccaccgaat atcccaattt gtgacataac gctttaattg cattaccttt tgaaacatct
     4621 ttggccataa attctaagaa gaatggctta cttgtcgtag catctacatt atcattgaac
     4681 acaccattca aatcaattct agcttctgta atattcgcta cataatctac acccatgacc
     4741 ttgggtacat cgccttgaat atatgctttg atatcatcaa cacgtttcat cggtaaacca
     4801 gttaattccg cttcaatatt catatattca tgttcgctgt cgtatataat ttgaccatca
     4861 tgatatgtaa gaacgaaaaa tcctctatct cgacaataat ctacaatttc atcgaaatcc
     4921 tgcttaccaa tcgatttact tacttctact tcttcattag tcatgttaat cgttttactg
     4981 ccgttataac taataatata gctatgatgt tcaggtaatt ttaaatctct agcagttgga
     5041 atcatacctt cagtaggtct accagatgct aaaacaacat aataaccttc atcttgaatt
     5101 gctgttaaat aatttgcagt ttcttctgat atcacattat ctgaatttag caatgtgtca
     5161 tccatatcta aaacgacaac tttataattt gtcatatcgc attaaatctc ctctctattt
     5221 cacattcaat actattttac aatataaagt gtctattggt atacaattcg ttctttaaca
     5281 ccactaacat taatatctac taattcagaa tgacatgtaa ctacatttct atttaaagcg
     5341 cgaactaatt cgccactatt ttctttgcga ctaaatatta aaatagttgg tccagcacca
     5401 ctaattacag ttgcataggc attatgttga ctagcaattg ttttcacttc atcaaattca
     5461 gcaattaaat gctgacgata cggttcatga aagccatctt gttgcatgag tttacctgct
     5521 aattcataat tgtgctgtgc taatgcacaa atcattgtat tactaattgc actactttta
     5581 accgcttcac tatgtgttaa tttttgtggt aaagcacgtc ttgatgcttc tgttttaagt
     5641 tcataagttg gtatcgttac aatcacatcc acgtctggta tgtcgatatg tgcaactgac
     5701 gtttctttcg agacatcatt ataatatcca gcgattaaac caccataaat ggtcggcgca
     5761 acattatcag gatgtccttc gatttcagtc gctaattgta atacctcatg tttagacagt
     5821 tggatgtcac caaaataatt tgcgatatat atagctccta ctaaagcaga agctgacgaa
     5881 cctaaccctc ttgccaatgg aatatcactt ctcatttcga tacataaatt aggcaagtca
     5941 acactatatt tagaagcaac ttgttgtgct acatgataaa taaagtttgt ttcgtcagta
     6001 ggcaattgct tcgatgcatc atcatggaaa atatatttcc attttgtccc tgatgtttcc
     6061 tttacagaca gatgcaaaaa tttatctaaa gccataccta tagaatcaaa gccaactcca
     6121 aggttggctg ttgatgcagg aattgttaac tccaaaacat tcgacatgtt ataaagctcc
     6181 tttaatataa tcgataatgc tatctttatc atttggcaat ggctttatcg gattatctag
     6241 tagtgaaata gcagtatcag gatcttttaa tccattacca gttaaaatag caactacttt
     6301 tttaccttga ggtaatttac cttgtctatg caatttaatt aaacctgcaa tagaagcatt
     6361 acttgctggt tcactaaaga caccttcttt agttgtcatt aactgatatg cttctagaat
     6421 ttcatcatca gtaacactat ctattaatcc atttgattct ttaagagcat tagtcgcctt
     6481 atcccaacta gcaggattac caattcgaat agcagttgca atcgtttcag gatttttaat
     6541 gactttattt tgaacaattg gtgatgcgcc ttcagcttgg aagccaaaca ttttcggcaa
     6601 ttgtgatcct ttagcttcat gatattcttt aaagcctttc caatatgcag taatattacc
     6661 tgcattacct acaggaatcg ctaaaatatc aggtgcttca ccgtctaatt gttgtacaat
     6721 ttcaaatgag cctgtctttt gtccttcgat tctaaatgga ttgacagagt ttacaagctc
     6781 gatttcgcca ctttttgcaa tttcttttac aatttctaaa gcttcatcaa agtttccttc
     6841 aatagaaacg atttctgcac catacattac tgcttgcgac aatttaccta atgcaatttt
     6901 accttctggt attacgacga tagcttttaa acctgctctc gctgcatatg ctgctgcaga
     6961 cgctgatgta tttccagtcg aagcgcatat tacaattttc ttaccttgct cttttgcttt
     7021 tgtcacagcc attaccatac cgcgatcttt aaatgaacct gtcggattgg caccttcata
     7081 cttcacatat aaatctatac ctagtatttt agacatattt tcacaatgaa tgagtggtgt
     7141 atttccctcg ttcaatgtta attttggtgt attttcattt actggtaaat gtgctttaaa
     7201 ctcttctact aatccttgcc atcttctcat tataattaaa ctccttctac tgggtatact
     7261 ttgtcaactt cgtatccatg cttagtgatt aattcttccg gtgatgattc caatccaact
     7321 ataacagcgg catatgattg attatcgtaa tttgcaactc ttaatgatcg gtgaaatggt
     7381 aatattgcct ttaactcatt ttcaaaattt tcaattgaac ctttgacatg attcactact
     7441 acaaagaaat tggatttttc tttaatatta atttctgcat ctgaatccat catttccctt
     7501 gttttatctg tctttaattc aaaatgtggt ggcaatgtgt gtaaatctga ttcaaagaat
     7561 aatgctacat tcaataaatc actgacaacg gcactacctg ttgctaaact gcctgctcct
     7621 tttccataaa acatcgtgtc accaacggca tcaccaatga cataaatcgc gttatattca
     7681 tcctctacag ctgctaattg atgcttttta tcaattaacg ttggttctac cgatgcatta
     7741 actttgccat tttcatatat tcccttacca atcaatttaa ttttataccc cagttgatcg
     7801 gctacattaa tatcagttaa agttacgcca ctaattcctc ttcgtttaac gtcgtttaat
     7861 ttaatgactt ggttaaatga taaatatgat gtaatgacaa ctttacgcgc tgcatctacc
     7921 ccttctacat catcagttgg atccgcttca gcaaaaccaa gtcttttcgc ttcatcaagt
     7981 gcttcctcaa atgtcgtttg ctctttagtc attttagata aaataaaatt agaggtacca
     8041 tttaaaattc ccataaattt tgaaatatta ttcgcattca aaccattatt tatggcattt
     8101 acgatcggaa taccacctgc tacactcgct tcaaacttta aagctacacc attttcttct
     8161 gctaaatctt ctaaaagttt aagatgtact gctaataaat ctttatttgc ggtaataaca
     8221 tgttttttat ttttaagtgc tgttcttaac caatctacag ttggttcaat tcctcccatg
     8281 acttcaacga taatatctaa tgaatcatca tttaaaattt cattaacatc ttcagttaaa
     8341 tgatattggc taatatttag cggtctcttt ttagatttat ctcgaacaag aatatgcttt
     8401 atgacaatat ctttatttaa tgtatcttga atttgctgtc ggttctcttc gatgatttta
     8461 acaacaccag atccgacagt acctaatcct aataatgcta tatttaattt tttcatttta
     8521 tgtacctccg tttgtgcttt tgagaaaaac aaatgtatta ttgaaaaaca ctagatgata
     8581 gtatagtata gaattattct ttatttttgt aaagttcgta atattcaaaa tataaataca
     8641 taatatcatt cttacttaca aaactgaata caattttctg attttttaga aaggttggca
     8701 tgcactatga aagtttctaa attcggtggt agctccgtct ccaatgctac tcaaattaaa
     8761 aaggttttaa atattgttaa ttctgatcca gagcgaaaga ttgttatcgt ttctgctcca
     8821 ggtaaaagac atgataatga tattaaaaca actgatttgt taatcagatt atatgaaaag
     8881 gtcattaatc atcttgatta tcatgataaa aaaagagaaa ttattcagcg ttatgatgat
     8941 attgtaaaag aattgcaaat ggatgaaagt attttacgga cgatagatgt gactttggaa
     9001 cattatatta atcaattaaa aaatgaacca aagagactat tagatgcatt actttcttgt
     9061 ggtgaagatt ttaatgcgca attgatagct ttatataata atagtcaagg tataccaaca
     9121 aaatatatat caccgaagga agcgggtatt tttgttactg acgtcccaca agaagcacaa
     9181 atattagata gtgcttactc tgaaattaaa aaattaagag attatgagga gaaactaatt
     9241 atcccaggat tttttggcgt atctcatgaa ggatatatag ttacatttcc acgtggcgga
     9301 tcagatataa ctggcgccat catatcaagt ggtgttagag ctacaattta tgaaaatttc
     9361 accgatgtgt ctggtattta taaagctaat ccaaatatca tcaaagatcc tgaattaatc
     9421 gaagaaatca cttatcgaga aatgcgtgaa ttatcttatg ctggttttag tgttttccat
     9481 gatgaagcct tacaaccact ttataaagat cgcatccctg tggtgattaa aaatacgaac
     9541 cgccctcaag ataaaggtac atttatagtg catgatagag aaataaatgc gaaaaatgtg
     9601 attagcggta taagttgtga taaagatttt actgttatta atatcaagaa gtatttaatg
     9661 aatagacaag tcggctttac tagaaagata ttaggtgtct tagaggataa taatatttca
     9721 tttgatcata tgccttcagg tattgatact atcagtatcg ttatgcgttc aaaacaaatt
     9781 caaaataaag aaacaaaagt attaaatgaa attcgtcaaa aatgtgatgt tgatgagcta
     9841 agtattgagc atgatttagc aattttaatg attgtcggcg aaggtatgaa taaagtcatc
     9901 ggtactgcaa ataaaattac acatgcctta gctgaatcaa aaattaactt aaaaatgatt
     9961 aaccaaggtg cttcggaaat ctcgatgatg tttggaattc atgtagatga tgctgaaaaa
    10021 gctgtattat ctacatatga gttttgctat cacggggttg cattaaaaaa cttgtgtgat
    10081 aaaaactaat ataaaagcaa ttcgtaacac atgtattcaa ctgcgttatg aattgctttt
    10141 tcttaattat ttattgttct ctggattgca tccttaatac gttgctcacc tactacaaat
    10201 tttaaaataa aaaattgata gtagcttaat gcatctatga cacgtttata attggaataa
    10261 tgatgatact gatggtgttg cattaaatca tacattagaa cgatttccgg tttaatataa
    10321 tccacatccc aatttaaact atggaagtaa atgttactct taggtatacg tatattcgga
    10381 tccaatctaa aaatccattc atcgtttact acatcataaa cgaaaatact cattattgtt
    10441 gtatcatcat attgcacata aacttttgca atttttgaaa gtgataaatc ttctttagct
    10501 attgcttgat cttgcttatc tatgtatagt aacgcatatg attgcggaat aactttcaca
    10561 atatcactta aacgcttacg ttccacgcat atttcaacaa tagaaggtaa ttttaattca
    10621 tcatttaaga aaagctgcat ggcaacttca ccgtgaaatt taaataattg cgatgatgtt
    10681 ttcattaaat tgtccactaa ttgttcttta gcattcattt cattcactct caaatacacc
    10741 tcctaagcaa gcgttttcac aaatatcatt atacatttta aaattaatga attcaatctt
    10801 caaaatacta tgagtgacct aattctgtca tttaaatgac cgttataaca taaattcgac
    10861 ataaacttga attcacgaat ctttcacgtc atattcattg aacatcaata tctgtcagtt
    10921 tataatttga ttataacaat gatgaactaa aatcaactaa taaaaatgtg ggaaattgaa
    10981 taacaattaa tctttattaa ttattattgt atacaaagtt aaagaagtca aaaaggattg
    11041 gtgaaaaaat gtctttttat gttgtactta tcattatcat tgtagcatta attggtatat
    11101 tagttttaaa tcaaaggtat agtaatagta aaatagatac cgaagtttat gcaagaaagc
    11161 aacttattaa aaagaacaaa gcattaagtg cagaaaatgc tgaattaaga agtcaaatgc
    11221 tgagttctaa taatgatgtt ggccaccatg catacaaaaa tgctaaaaga gaattacgca
    11281 agattttaga tagctatctc gaaaatggta aattaaaata ttacgatatt atcgttacaa
    11341 gcaatttagc tactaaacat ccgtttttcg agtatgcacg ttcatttgat tttatcattg
    11401 tttcagatat cggtttaata aacgttgatg taaaaagctg gggtgaaaaa acattttatc
    11461 actttgatgt acctgatgag catgatacag aaatgagcaa tagtaatatt gaaaaagttg
    11521 tcggtcatta cattagccag caatatcatg atcagtttaa ttcatcaaga aagtctatct
    11581 atacttttac agaaacagtt caaccaaatc gtgttattta tgatttttat gattatgatc
    11641 cgtatcaatt agcagcaaat aatgctaaag cattaaagga tcatattgaa caaaaattta
    11701 actttaaagt ccaaagtacc ggtgttattt actttagtga tggtacagtt aatatcattc
    11761 aaggttctga agaaagagat aaatatgttg atacagtttc aacaaaatct tcgttacgac
    11821 gtattattag cgaagccata gagctatcta aacacccttt aaataaagaa caggttgatc
    11881 aaatcactgc tatattcaag taaaatcaaa ggcataataa tccattacgc tcgatacgca
    11941 ctatggttat tatgccttta aattatttct atat
//
LOCUS       DAPSKH010000070        11768 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.070, whole genome shotgun sequence.
ACCESSION   DAPSKH010000070 DAPSKH010000000
VERSION     DAPSKH010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 11768)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11768)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11768
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.070"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            67..993
                     /locus_tag="RPH49_002292"
     CDS             67..993
                     /locus_tag="RPH49_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125413.1"
                     /translation="MGKYIFKRFIYMLISLFIIITITFFLMKLMPGSPFNDAKLNAEQ
                     KEILNEKYGLNDPVATQYLHYLKNVVTGDFGNSFQYHNQPVWDLIKPRLLPSFEMGLT
                     AMFIGVILGLILGVAAATKQNSWVDYTTTVISVIAVSVPSFVLAVLLQYVFAVKLRWF
                     PVAGWEGFSTAVLPSLALSAAVLATVSRYIRAEMIEVLSSDYILLARAKGNSTMRVLF
                     GHALRNALIPIITIIVPMLASILTGTLTIENIFGVPGLGDQFVRSITTNDFSVIMAIT
                     LLFSTLFIVSIFIVDILYGVIDPRIRVQGGKK"
     gene            993..2063
                     /locus_tag="RPH49_002293"
     CDS             993..2063
                     /locus_tag="RPH49_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125414.1"
                     /translation="MAENKNNLSINEDHSNAAMTHTSDAIASSDFIIRELDFNQEPEM
                     QRESKNFWQDAWAQLKRNKLAVVGMIGLIIIVIFAFIGPVINKHDYAEQNVQHRNLPA
                     KIPVLDKVPFLPFDGKDADGKDAYKAANAKENYWFGTDQLGRDLWTRTWKGAQISLFI
                     GVVAAMLDIFIGVVYGAISGFFGGRVDTIMQRILEVIASIPNLIVVILFVLIFEPSIW
                     TIILAMSITGWLGMSRVVRGEFLKLKNQEFVMASKTLGASKFKLIFKHILPNTLGAIV
                     VTSMFTVPSAIFFEAFLSFIGIGVPAPQTSLGSLVNDGRAMLLIYPHELFIPAMILSL
                     LILFFYLFSDGLRDAFDPKMRK"
     gene            2079..3161
                     /locus_tag="RPH49_002294"
     CDS             2079..3161
                     /locus_tag="RPH49_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125415.1"
                     /translation="MTERILEVNDLHVSFDITAGEVQAVRGVDFYLNKGETLAIVGES
                     GSGKSVTTKAITKLFQGDTGRIKKGEILFLEEDLAKKPENELIKLRGKDISMIFQDPM
                     TSLNPTMQIGKQVMEPLIKHKNYSKAQAKKRALEILNLVGLPNAEKRFKAYPHQFSGG
                     QRQRIVIATALACEPKVLIADEPTTALDVTMQAQILDLMKELQQKIDTAIIFITHDLG
                     VVANIADRVAVMYGGQMVETGDVNEIFYDPKHPYTWGLLSSMPDLSTTNDTPLLAIPG
                     APPDLLHPPKGDAFARRSQYALDIDFKVEPPWFKVSPTHFVKSWLLDARAPKVELPEL
                     VKQCMKPMPNNYEKPLKVERVSFNEK"
     gene            3151..4092
                     /locus_tag="RPH49_002295"
     CDS             3151..4092
                     /locus_tag="RPH49_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125416.1"
                     /translation="MKNDEVLLSIKNLKQYFNAGKKNEVRAIENISFELYKGETLGLV
                     GESGCGKSTTGKSIIKLNDITSGEILYEGIDIQKIRKRKDLLKFNKKIQMIFQDPYAS
                     LNPRLKVMDIVAEGIDIHHLATDKRDRKKRVYDLLETVGLSKEHANRYPHEFSGGQRQ
                     RIGIARALAVEPEFIIADEPISALDVSIQAQVVNLLLKLQREKGITFLFIAHDLSMVK
                     YISDRIAVMHFGKIVEIGPADDIYQYPLHDYTKSLLSAIPQPDPESERSRKRFSYIDD
                     EANNHLRQLHEIRPQHFVFSTEEEAAQLRENKLVTQN"
     gene            4110..5765
                     /locus_tag="RPH49_002296"
     CDS             4110..5765
                     /locus_tag="RPH49_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5125417.1"
                     /translation="MTRKFRTLILILIATIALSGCANDDGIYSDKGQVFRKILSSDLT
                     SLDTSLITDEISSEVTAQTFEGLYTLGKGDKPVLGVAKAFPEKSKDGKTIKVKLRSDA
                     KWSNGDKVTAQDFVYAWRKTVDPKTGSEFAYIMGDIKNASDISTGKKPVEQLGIKALN
                     DETLQIELEKPVPYINQLLALNTFAPQNEKVAKKYGKNYGTAADRAVYNGPFKVDDWK
                     QEDKTLLSKNQYYWDKKNVKLDKVNYKVIKDLQAGASLYDTESVDDAVITADQVNKYK
                     DNKGLNFVLTTGTFFVKMNEKQYPDFKNKNLRLAIAQAIDKKGYVDSVKNNGSIPSDT
                     LTAKGIAKAPNGKDYASTMNSPLKYNPKEARAHWEKAKKELGKNEVTFSMNTEDTPDA
                     KISAEYIKSQVEKNLPGVTLKIKQLPFKQRVSLELSNNFEASLSGWSADYPDPMAYLE
                     TMTTGSAQNNTDWGNKEYDQLLKVARTKLALQPNERYENLKKAEEMFLGDAPVAPIYQ
                     KGVAHLTNPQVKGLIYHKFGPNNSLKHVYIDKSIDKETGKKKK"
     gene            5976..7691
                     /locus_tag="RPH49_002297"
     CDS             5976..7691
                     /locus_tag="RPH49_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDY5125418.1"
                     /translation="MGKLIKYISILIVIVLVLSACGKSSNKDEGVKDATKTETSKHKG
                     GTLNVALTAPPSGVYSSLLNSTHADAVVEGYFNESLLATDKKIRPKAYIASWKDIEPA
                     KKIEFKIKKGIKWHDGNELKIDDWIYSIEVLANKDYEGAYYPSVENIQGAKDYHEGKT
                     DHISGLKKIDDYTMQVTFDKKQENYLTGFITGPLLSKKYLSDVPIKDLAKSDKIRKYP
                     IGIGPYKVKKIVPGEAVQLVKFDDYWQGKPALDKINLKVIDQAQIIKAMEKGDIDVAN
                     DATGAMAKDAKSSNAGLKVLSAPSLDYGLIGFVSHDYDKKSNKTGKVRPKYEDKELRK
                     AMLYAIDREKWIKAFFNGYASEINSFVPSMHWIAADPKELNDYKYDPEKAKKILDKLG
                     YKDRDGDGFREDPKGNKFEINFKHYSGSNPTFEPRTAAIKDFWEKVGLKTNVKLVEFG
                     KYNEDLANASKDMEVYFRSWAGGTDPDPSDLYHTDRPQNEMRTVLPKSDQYLDDALDF
                     EKVGIDEKKRKDIYVKWQKYMNDELPGLPMFQGKSITIVNDKVRNLDIEIGTDQSLYN
                     LTKEA"
     gene            7742..8728
                     /locus_tag="RPH49_002298"
     CDS             7742..8728
                     /locus_tag="RPH49_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125419.1"
                     /translation="MNNVLLEVKDLETSLKINNEWLATVENISFELSKGEVLGIVGES
                     GCGKSILSKSIIKLLPEKISKLSSGEVIFDGKRIDTLNEKQLLDIRGNDIAMIFQEPM
                     TALNPVFTIKNQLVESIKSHKKISKKEANNLAKDLLKKVGIARQDEILNSYPHQLSGG
                     MRQRVMIAMAISCSPKLLIADEPTTALDVTIQAQILDLLKELQKETQMAIMMITHDLS
                     VVAEFCDKVLVMYAGQIVEFGGIKEILHNPKHPYTQKLLSTIPKLKEEQKRLETIEGI
                     VPSIQAFHVNKCRFANRCNKKMDICNNQSPKMHVCEDVIVRCHLYKNEYKEI"
     gene            8731..9711
                     /locus_tag="RPH49_002299"
     CDS             8731..9711
                     /locus_tag="RPH49_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDY5125420.1"
                     /translation="MENILEVNQIKKYYKIKTGLLQKTQYVKAVDDVSFSIKKGQTFG
                     LVGESGCGKSTLGKVIIRLEDATSGSIIVNGEDITRLQGKKLRKSRQQYQMIFQDPYA
                     SLNPMQMVGDIISEPILNYKKLPKEEIKKEVLYLLKCVGLSEDAYYKYAHEFSGGQRQ
                     RVGIARALALRPSLIVADEPVSALDVSVQSQVLNLLKDLQEQFNLSYLFIAHDLSVVK
                     HISDVIGVMYLGHIVEIASDKEIYENPKHPYTKALISSIPQIDKHNNNRIILKGELPS
                     PSNPPQGCPFHTRCPIAKDKCKENIPQLKDIGDEHQVACFYVNKVGDLNG"
     gene            9704..10666
                     /locus_tag="RPH49_002300"
     CDS             9704..10666
                     /locus_tag="RPH49_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125421.1"
                     /translation="MVKLILKRLGLMIPLLILISIVVFSLAIIQPGDPFSDLQNGKIK
                     QEAINAQREKLGLNDSISHQYIRWVNHVIHGDLGESIKYKRPVIDVIEERIPNTILLG
                     AMSLIITYIISFALGITSGRYSYSLTDYTVQIFNYLMLAIPSFIAGVFAIFIFSFELQ
                     WFPFQGSVDINLKEGTFEYYMSKIYHTFLPALTLGLLSTAGYIQYLRNDIIENSKKDY
                     VLTARSKGLSMNKIYNKHILRNSLIPIITFLGADIVSILGGAVITETIFSYNGIGKLF
                     LESVIGQDYPLMMALTLFFSFLGLLGNLISDITYGFIDPRIRSN"
     gene            10678..11559
                     /locus_tag="RPH49_002301"
     CDS             10678..11559
                     /locus_tag="RPH49_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125422.1"
                     /translation="MQNKSKSPFKIALSKFIHNKIAMLSIIFLLIITIVSIIAPLIAP
                     FPVNQQDLLNIKGEMTAQNILGTDSGGRDNFSRLLYAGRISLSIGITSTIGMLLIGIT
                     VGVISGYFGSIVDTLLMRITEFVMLFPFLIFAIVLNAALGDKIKNPYGSAIILVLVII
                     VLSWGGIARLVRGKVLQEKENEYFLAAKSIGTPTYKIILKHLLPNILSVVIVQATLLF
                     AGMIVVESGLSFLGFGISKAIPSWGNMLSDAQEGDVISGKPWIWMPPAIMITLTILSI
                     NFVGEGLKDAFNPRGRR"
BASE COUNT         4302 a         1586 c         2190 g         3690 t
ORIGIN      
        1 agatttcaga aaattttgaa gggaatggaa atttagaaat cggaatttgt tagaggaggg
       61 gattagatgg ggaaatatat tttcaaacga tttatttata tgcttatttc tttatttatt
      121 attattacaa ttacattttt cttaatgaaa ttaatgccag gttcgccatt taacgatgct
      181 aaattaaatg ctgaacaaaa agaaatttta aatgaaaaat atggattaaa tgatcctgta
      241 gctacgcagt atttacatta tttaaaaaat gttgttacag gcgattttgg taattcattc
      301 cagtatcata atcaacctgt gtgggatttg attaaaccga gactactacc ttcttttgaa
      361 atgggtctta cagcaatgtt catcggtgtg atactgggac ttattttagg tgttgcagca
      421 gctactaaac aaaattcttg ggttgactat acaactacag ttatttcagt tattgcagta
      481 tctgtaccat cttttgtact tgctgtactt ttacaatatg tatttgcagt taaattaaga
      541 tggttcccag tagctggatg ggaaggtttt tcgaccgcgg tattaccgtc acttgcatta
      601 tctgcagctg ttttagcaac tgtctccaga tacataagag cagagatgat tgaggtatta
      661 agttcagact acattttatt agcgagagct aaaggtaatt cgacaatgcg tgtacttttt
      721 ggacatgcac ttagaaatgc tttaattcca attattacaa ttatcgttcc catgttagca
      781 agtattttaa caggcacttt aactattgaa aatatttttg gggttcctgg attaggggat
      841 caattcgtac gttcaattac aacaaatgat ttttcagtaa tcatggcaat cacactatta
      901 tttagcacac tgtttatcgt ttctattttt attgtagata ttttgtacgg tgtgatagat
      961 ccacgaattc gtgttcaagg aggtaaaaaa taatggctga aaataaaaac aatttgtcga
     1021 ttaacgaaga tcattctaat gcagctatga cgcatacctc tgacgctatc gcatcatctg
     1081 attttattat tagagaatta gattttaatc aggaacctga aatgcaacga gaaagcaaaa
     1141 acttttggca agatgcttgg gctcaattaa aacgaaataa gttagctgtt gtcggtatga
     1201 taggtttaat tatcattgta atatttgctt ttatcggtcc agttataaat aaacatgatt
     1261 atgctgaaca aaatgtacaa catagaaatc ttccggcaaa aatacctgta ttagacaaag
     1321 ttccattttt accttttgat ggtaaagatg cagatggcaa ggatgcttat aaagcagcaa
     1381 atgctaaaga aaattattgg tttggtactg atcagttggg tcgagattta tggacaagaa
     1441 catggaaagg tgctcaaatt tcattgttta tcggtgttgt tgcagcgatg ttagatattt
     1501 ttattggcgt tgtatatggt gcgatttctg gattcttcgg tggacgtgtc gatacgatta
     1561 tgcaacgtat acttgaagtc atagcatcta ttccgaattt aattgtcgta attttatttg
     1621 tattaatttt tgaaccatcc atttggacaa ttatattggc tatgtctatc acaggctggt
     1681 taggcatgag cagagttgta cgtggagaat ttttaaaatt aaaaaatcaa gagtttgtca
     1741 tggcttcgaa aacattgggg gcttcaaaat tcaaattgat atttaagcat attttaccta
     1801 atacattagg tgctatcgtg gttacatcaa tgtttacagt acctagtgct attttcttcg
     1861 aagcattttt aagtttcatt ggtataggtg tacccgcacc tcaaacatcg ttagggtcat
     1921 tagtaaatga tgggcgcgca atgttattaa tttatccaca tgaattattt ataccagcaa
     1981 tgattttaag tttattaatt ctattctttt acttatttag tgatggatta cgtgatgcat
     2041 ttgatccgaa aatgcgtaaa taaaaggggg catagcatat gactgaaaga atattagaag
     2101 taaatgattt gcatgtttcc tttgatatta cagcagggga agtgcaggca gtgagaggtg
     2161 tagattttta tttaaacaaa ggggaaacat tggcaattgt tggtgaatca ggttcaggta
     2221 aatctgtaac aacaaaagca attacaaaat tattccaagg ggacacagga agaattaaaa
     2281 agggagaaat tttattttta gaggaagatt tagcaaaaaa acctgaaaat gagttaatta
     2341 aattacgtgg caaagatatt tcaatgatct ttcaagatcc aatgacatct ttaaacccaa
     2401 cgatgcaaat tggtaaacaa gtcatggaac cattaattaa gcacaaaaat tatagtaaag
     2461 cacaagctaa aaagcgcgca ttggaaatac taaatcttgt aggtttacca aatgcagaaa
     2521 aaagatttaa agcatatcca catcaatttt caggtggaca aaggcaaaga attgttattg
     2581 caaccgcatt agcttgtgaa cctaaagtgc tcattgctga tgaaccaacg actgcattag
     2641 acgtaacgat gcaggcacaa attttagatt taatgaaaga actacaacaa aaaatcgata
     2701 cagcaattat ttttataacg catgatttag gggttgttgc gaatattgct gatagagtgg
     2761 cagttatgta tggtggtcaa atggttgaaa caggagatgt taacgaaata ttttatgatc
     2821 caaagcatcc atatacatgg ggattattat cgtcaatgcc tgatttatca acaacaaatg
     2881 acacaccatt actagcgatt cctggagcgc cacctgattt attacaccca cctaaaggtg
     2941 atgcatttgc gagacgtagt caatatgcat tagatattga ttttaaagta gaaccaccgt
     3001 ggtttaaagt ttcaccgaca cattttgtga aatcttggtt attagacgca cgtgcaccaa
     3061 aagttgaact acccgagctg gtaaaacaat gtatgaaacc gatgcctaat aattatgaaa
     3121 aaccactcaa ggtagaaagg gtgtcgttca atgaaaaatg atgaagtgct attatctatt
     3181 aaaaatttaa agcaatattt taacgcagga aagaaaaacg aagtgagagc gattgaaaat
     3241 atttcgtttg aattatacaa aggggaaaca ttaggtttag taggagaatc ggggtgtggt
     3301 aaatctacaa ctggtaaatc aattatcaaa cttaatgata ttacaagtgg agaaattttg
     3361 tatgagggta ttgatataca aaagattcgt aaacgcaaag atttgcttaa atttaataaa
     3421 aagatacaga tgatttttca agacccatat gcgtctttaa atcctaggtt aaaagtaatg
     3481 gatatagtag ctgaaggtat tgatatccat catttagcaa ctgataaacg tgaccgtaaa
     3541 aaacgtgtct atgatttact tgaaactgtt ggattaagta aagaacatgc caatcgttat
     3601 cctcatgaat tttcaggcgg acaacgccaa cgtattggaa ttgcccgtgc attagccgtt
     3661 gaaccagaat ttattattgc agatgaacct atttcagcat tggatgtttc gattcaagct
     3721 caagtagtca atttgttatt aaaattacag cgtgaaaaag gtattacatt cctatttatt
     3781 gcacatgatt tatcaatggt gaagtatatc tctgatcgaa ttgcagtcat gcattttggg
     3841 aaaattgtag aaatcggacc agcagacgat atttatcaat atccattaca tgattatact
     3901 aagtctttat tgtcggcaat tcctcaaccg gatcctgaat cggaacgtag tcgcaaacga
     3961 tttagttata ttgatgatga agcaaataat catttaagac aattacatga aataagacca
     4021 cagcattttg tctttagtac tgaagaagaa gcggcacaac tacgagaaaa taaattggtg
     4081 acacaaaatt aagggaaggg ggaaatgcaa tgacgagaaa atttagaaca cttattttaa
     4141 ttttgattgc tacaattgca ttaagtggtt gtgctaatga tgatggtatt tattcagata
     4201 aaggtcaagt attcagaaaa attttgtcat cagacttaac atcccttgat acatcattaa
     4261 taacggatga aatatcttct gaagtgactg cgcaaacatt cgaaggttta tacacattag
     4321 gaaaaggtga caaaccggtg ttaggtgttg cgaaagcttt tcctgaaaag agtaaagatg
     4381 gtaaaactat aaaggttaaa ttaagaagcg atgctaaatg gagcaatggt gacaaagtga
     4441 ctgcacaaga ctttgtttat gcttggagaa aaacagttga ccctaaaaca ggttctgaat
     4501 ttgcatacat tatgggggac attaaaaatg cgagtgatat tagtactggt aagaaacctg
     4561 tagagcaatt aggtatcaaa gcattaaatg atgaaacatt acaaattgaa ttagaaaagc
     4621 cggttccata tattaatcaa ttattagcac ttaatacatt tgcacctcaa aatgaaaaag
     4681 ttgccaaaaa atatggtaaa aattacggta cggcagctga tagagcggta tacaatggtc
     4741 catttaaagt tgatgattgg aaacaagaag ataaaacctt actatctaaa aatcagtatt
     4801 attgggataa aaagaatgta aaattagata aagtgaatta taaagttatt aaagacttac
     4861 aagccggtgc atcattgtat gatactgaat cagtagatga cgcagttatt actgcagatc
     4921 aagtaaataa atataaagat aacaaaggat taaactttgt gttaacgact gggacatttt
     4981 ttgtaaaaat gaatgaaaaa caatatcctg attttaaaaa caaaaattta agactggcta
     5041 tcgcacaagc aatagataaa aaaggatacg ttgattcagt gaaaaacaat ggctcaattc
     5101 cttccgatac actaacagcc aaaggaattg cgaaagcacc gaatggcaaa gattatgcga
     5161 gtaccatgaa ttcaccgtta aaatataatc ctaaagaagc aagagcacat tgggaaaaag
     5221 ctaaaaaaga gttaggtaaa aatgaagtga cattttctat gaacacagaa gatacgccag
     5281 atgcaaaaat atctgcagaa tatatcaaat cgcaagttga gaaaaattta ccaggtgtta
     5341 ctttaaaaat taagcaattg ccatttaagc aaagagtttc attagagtta agtaacaatt
     5401 ttgaagcatc acttagtggt tggtctgcag attaccctga tcctatggct tatttagaaa
     5461 caatgaccac aggtagcgca caaaataata cagactgggg taataaagaa tatgatcaat
     5521 tacttaaagt agcaagaacc aaattggcac ttcaaccgaa cgaacgatat gaaaacttga
     5581 aaaaagcaga agaaatgttc ctaggagatg caccggtagc accaatttat caaaaaggtg
     5641 ttgcacattt aacaaatcct caagtaaaag gattaattta ccataaattt ggtccaaata
     5701 actcacttaa acatgtctat attgataaat cgatagataa agaaacaggt aagaagaaaa
     5761 aataatatgc tttgtaaatt aggctggaga catatctcca gtctttttgt gttggataga
     5821 aactttggga ataaaaattt aaaataagtc gttttttaaa ttactgaaat tgattaaatg
     5881 cataaataac tgaatattct aaaaataaac ttgtaataat tttttctatg agtaaactaa
     5941 aaagaaaaat tagattgaaa gtaggaggca tataaatggg gaagctaatt aaatatattt
     6001 caatacttat tgttatcgtt ttagtgttga gtgcttgcgg aaaaagcagt aataaagacg
     6061 aaggagtaaa agatgctact aaaacagaaa cctcaaaaca taaaggtggt accttaaatg
     6121 tagcattaac agcacctcca agtggtgttt attcttcgtt attaaatagt acacatgcgg
     6181 atgctgtagt tgagggatat tttaacgaaa gcttattagc aactgataaa aaaatacgtc
     6241 ctaaggcata tattgcttca tggaaggaca tcgagccggc taagaaaata gaatttaaaa
     6301 ttaaaaaagg tattaaatgg catgatggta atgaattgaa aattgatgat tggatttatt
     6361 caattgaagt cttagctaac aaggactacg aaggtgctta ttatccaagt gtagaaaata
     6421 tccaaggtgc gaaagattat catgaaggaa aaactgatca tattagcgga ttgaagaaaa
     6481 tagatgacta cactatgcag gttacatttg ataaaaaaca agaaaattac ttaacaggat
     6541 ttattactgg acctttatta agtaaaaaat atttatcaga tgtaccaatt aaagatttag
     6601 cgaaatcaga taaaatccga aaatatccta ttggtattgg accgtataaa gttaagaaaa
     6661 tcgttccagg tgaggctgtt caactcgtta aatttgatga ttattggcaa ggtaagcctg
     6721 cactagacaa aatcaattta aaagttattg atcaagctca aattattaag gcaatggaaa
     6781 aaggcgatat tgatgttgcg aatgatgcta ccggtgcaat ggcaaaagat gctaagtcat
     6841 ctaatgctgg tctcaaggta ttatctgcgc caagcttaga ctacggttta ataggattcg
     6901 tatctcatga ttacgataaa aaatctaata aaactggtaa agtgagacca aaatatgaag
     6961 acaaagaatt acgtaaagca atgctttatg caattgatag agaaaaatgg atcaaagcat
     7021 ttttcaatgg ttacgctagt gaaataaata gttttgtacc atcaatgcat tggatagctg
     7081 ctgatcctaa ggaactaaac gattataaat atgatcctga aaaagctaaa aaaatcttag
     7141 ataagttagg ttataaagat agagatggtg atggatttag agaagatcct aaaggtaata
     7201 aatttgagat taactttaaa cattattcag gttcaaatcc tacttttgaa ccaagaactg
     7261 ctgcgataaa agatttctgg gaaaaagttg gcttgaaaac aaatgtgaag ttagtagaat
     7321 tcggtaaata taatgaagac ttagcaaatg catctaaaga tatggaagtg tactttagat
     7381 catgggcagg aggtacagat ccagatccat cagatttata ccacactgat agacctcaaa
     7441 atgaaatgag aacagtttta ccaaaatcag atcaatattt agatgatgca ttagacttcg
     7501 aaaaagtagg cattgatgaa aagaaacgta aagatattta tgttaaatgg caaaaatata
     7561 tgaatgatga gttacctgga ttaccaatgt tccaaggtaa atcgataact attgttaacg
     7621 ataaagtacg aaacttagac attgaaattg gaactgatca aagtttatat aatttaacta
     7681 aagaagctta gtaatgtaac ctcgacgatt ttgtcgaggt ttacttatat ggggggatgt
     7741 tatgaataat gtattgttag aggttaaaga tttagaaaca tcattaaaaa taaataatga
     7801 atggttagca actgttgaaa atatttcttt tgaattatct aaaggagaag ttttgggtat
     7861 agtaggggaa tctggttgcg gtaagtccat attaagtaag tcaattatta aattattacc
     7921 agaaaagata tctaaactaa gtagtggaga agttatattt gatggtaaac gaatcgatac
     7981 gctcaatgag aagcaattgc tagatattcg aggaaatgat attgctatga tttttcaaga
     8041 acctatgact gctttaaatc ctgtatttac cataaaaaat caacttgtgg aatctataaa
     8101 atcacataaa aaaatttcta aaaaagaagc aaataactta gcaaaagatt tactaaaaaa
     8161 agttggaatt gctagacaag atgaaatatt aaatagctat cctcatcaat tatctggtgg
     8221 tatgagacaa agagtaatga ttgcaatggc catttcatgt tctcctaaat tattaattgc
     8281 tgatgaacct acaacagcat tggatgtcac gattcaagcg caaatattag acttattaaa
     8341 agaattgcaa aaggaaacgc aaatggcaat tatgatgatt acacatgatt tgagtgtagt
     8401 tgctgagttt tgcgataaag tcttagttat gtatgcaggt caaattgtag aatttggagg
     8461 cataaaagaa atactacaca atccgaaaca tccttatacc caaaaattat tatcaacaat
     8521 tccaaaactt aaagaagagc agaaacgact tgaaacgata gaaggaattg tgccatcaat
     8581 ccaagcattt cacgttaata agtgcagatt tgcaaataga tgtaacaaaa aaatggatat
     8641 ttgtaataat caatctccta aaatgcatgt ttgtgaagac gtcattgtac gttgtcattt
     8701 gtacaaaaat gaatataagg agatataaga atggaaaata ttttagaagt caaccaaata
     8761 aaaaaatact acaaaattaa aactggatta ttacaaaaaa ctcagtacgt taaagctgtt
     8821 gatgacgtat cgttttcaat aaaaaaagga caaacttttg gattagtagg agaatcgggt
     8881 tgtggtaagt caacgttagg taaagtgatt atcaggcttg aagatgcaac ttcaggctca
     8941 ataattgtta atggtgaaga tataacaaga ttacaaggta aaaaactcag aaaatcacga
     9001 caacaatatc agatgatatt tcaagatccg tatgcatcat tgaatccgat gcaaatggtt
     9061 ggagatatca tttcagaacc tattttaaat tataaaaaat tgccaaaaga agaaataaaa
     9121 aaagaagtac tatatttatt aaaatgtgtt ggcctaagtg aagatgcata ttataaatat
     9181 gcacatgaat tttcaggtgg acagagacaa agagtgggaa ttgcaagagc attggctttg
     9241 cgtccgagtt taattgttgc tgatgagcct gtaagtgcat tagatgtatc tgttcaatct
     9301 caagtactga atttattaaa agatttacaa gaacaattta acttaagcta tttatttatc
     9361 gcacatgatt taagtgtagt aaaacatata agtgatgtca ttggagttat gtatttaggt
     9421 catatagttg aaatcgcatc tgataaagaa atttatgaaa atcccaaaca tccatataca
     9481 aaagcgttga tttcatcaat accacaaatt gataaacata ataacaatag aattatatta
     9541 aaaggagaat taccttcgcc aagtaatccg ccgcaaggtt gtccttttca tacaagatgt
     9601 ccgattgcaa aagataaatg taaagaaaat ataccacaat taaaggacat tggtgatgaa
     9661 catcaagttg cttgttttta tgtaaataaa gtaggtgatt taaatggtta aattaatatt
     9721 aaagagatta ggtttaatga ttccgttact aattttaatt tctattgttg tattttcatt
     9781 agctatcatt caaccaggag atccattttc agatttacaa aacggaaaaa taaaacaaga
     9841 agcgataaat gcacaaaggg aaaagttagg cctcaacgac tctatatcac atcaatacat
     9901 tagatgggtc aatcatgtta tacatggtga tttaggggag tcaatcaaat ataaaaggcc
     9961 ggtaattgat gttattgagg aaagaattcc aaatacaata ttactcggtg ctatgtcatt
    10021 aattattact tatattatct catttgcttt aggaataacg tcaggtagat attcttacag
    10081 tttgactgat tatactgtgc aaatatttaa ttatttgatg ttagctattc catcttttat
    10141 tgcgggagta tttgcaattt ttattttttc ttttgaatta caatggtttc cgtttcaagg
    10201 ttctgttgat attaacctta aagaaggtac ttttgaatat tatatgagta aaatttatca
    10261 tacatttttg cctgcattaa ctttaggatt attatctact gctggttata ttcaatattt
    10321 acgtaatgat attattgaaa attctaaaaa agattatgta ttgacggcaa ggtcaaaagg
    10381 attatctatg aataaaattt ataataaaca tatattgaga aattctttaa tacctattat
    10441 tacattttta ggtgctgata ttgtaagtat tttaggtgga gctgtgatta ctgagactat
    10501 cttttcatat aacggtatcg gtaaattatt tttagaatcg gtaataggtc aagactatcc
    10561 attaatgatg gcattaacgt tgtttttctc atttttaggt ttactgggta atttgatttc
    10621 tgatattact tatggattta tagatccaag aattagaagt aactaggggg gattggaatg
    10681 caaaataagt caaaatcgcc ttttaaaatt gcattgtcta aatttattca taataaaatt
    10741 gcaatgttat cgattatttt tttattaatc ataactattg tatcaattat agcgccatta
    10801 atagctcctt ttccagtgaa ccaacaagat ttattaaata taaaaggtga aatgacagca
    10861 caaaacattc ttggtacaga ctccggtggt agggataact ttagtcgttt gttatatgca
    10921 ggtcgtattt cattatccat tggaattaca tctacaatag gaatgctttt gattggaatt
    10981 acagttggag tgatttctgg ttattttgga agtattgttg atacattatt aatgagaata
    11041 accgaatttg ttatgttatt tccattttta atatttgcaa ttgtattaaa tgctgcactt
    11101 ggagataaaa ttaaaaatcc ttatggatct gccataattc ttgttctagt tattatcgta
    11161 ttaagttggg gaggtattgc aagacttgtt cgtggtaaag tacttcaaga aaaagaaaat
    11221 gaatactttt tggcagcaaa atcaattggt acacccacat ataaaattat tttgaaacat
    11281 cttttgccga atatattaag tgtagttatc gtacaagcaa cattgttatt tgccggtatg
    11341 attgtagtgg aatcaggatt gagtttttta ggattcggaa ttagtaaagc aatcccatct
    11401 tggggtaata tgttgagtga tgctcaagaa ggggatgtta taagtggtaa accgtggata
    11461 tggatgccac ctgctataat gattacatta actatattaa gtataaactt tgtaggtgaa
    11521 gggcttaaag atgcttttaa tcctagaggt agacgttaaa taataaacag gctgggacat
    11581 aaatccctaa aaaacagcag taagataatt ttcaattaga aaatatctta ctgctgttct
    11641 ctatttatac aatacttcgt attgaatggc ttcgctttgc ccatctggca cattactgta
    11701 aaattctata aatagaattt ttgatgatgg gtcccttcct agggtgccgt ctcagcctcg
    11761 gtcttcga
//
LOCUS       DAPSKH010000071        11608 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPSKH010000071 DAPSKH010000000
VERSION     DAPSKH010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 11608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11608
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.071"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            39..1439
                     /locus_tag="RPH49_002302"
     CDS             39..1439
                     /locus_tag="RPH49_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125423.1"
                     /translation="MDFNKENINMVDAKKAKKTVVATGIGNAMEWFDFGVYAYTTAYI
                     GANFFSPVENADIRQMLTFAALAIAFLLRPIGGVVFGIIGDKYGRKVVLTSTIILMAF
                     STLTIGLLPSYDQIGLWAPILLLLARVLQGFSTGGEYAGAMTYVAESSPDKLRNSLGS
                     GLEIGTLSGYIAASIMIAVLTFFLTDEQMASFGWRIPFLLGLFLGLFGLYLRRKLEES
                     PVFENDVATQPERDNINFLQIIRFYYKDIFVCFVAVVFFNVTNYMVTAYLPTYLEQVI
                     KLDATTTSVLITCVMAIMIPLALMFGKLADKIGEKKVFLIGTGGLTLFSIIAFMLLHS
                     QSFVVIVIGIFILGFFLSTYEATMPGSLPTMFYSHIRYRTLSVTFNISVSIFGGTTPL
                     VATWLVTKTGDPLAPAYYLTAISVIGFLVITFLHLSTAGKSLKGSYPNVDNEQDRAYY
                     AEHPKEALWWVKERKN"
     gene            1983..3359
                     /locus_tag="RPH49_002303"
     CDS             1983..3359
                     /locus_tag="RPH49_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid--CoA ligase"
                     /protein_id="HDY5125424.1"
                     /translation="MNVILEQLKTHTQNKPNDIALHIDDETITYSQLNARITSAVESL
                     QKYSLNPVVAINMKSPVQSIICYLALHRLHKVPMMMEGKWQSTIHRQLIEKYGIKDVI
                     GDTGLMQSIDSPMFIDSTQLQHYPNLLHIGFTSGTTGLPKAYYRDEDSWLASFEVNEM
                     LMLKNENAIAAPGPLSHSLTLYALLFALSSGRTFIGQTTFHPEKLLNQCRKISSYKVA
                     MFLVPTMIKSLLLVYNNEHTIQSFFSSGDKLHSSIFKKIKNQANDINLIEFFGTSETS
                     FISYNLNQQAPVESVGVLFPNVELKTTDHDHNGIGTICIKSNMMFSGYVSEQCINNDE
                     WFVTNDNGYVKEQYLYLTGRQQDMLIIGGQNIYPAHVERLLTQSSSIDEAIIIGIPNE
                     RFGQIGVLLYSSDVTLTHKNVKQFLKKKVKRYEIPSMIHHVEKMYYTASGKIAREKMI
                     SMYLRGEL"
     gene            3361..4500
                     /locus_tag="RPH49_002304"
     CDS             3361..4500
                     /locus_tag="RPH49_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiolase family protein"
                     /protein_id="HDY5125425.1"
                     /translation="MNQAVIVAAKRTAFGKYGGTLKHLEPEQLLKPLFQHFKEKYPEV
                     ISKIDDVVLGNVVGNGGNIARKALLEAGLKDSIPGVTIDRQCGSGLESVQYACRMIQA
                     GAGKVYIAGGVESTSRAPWKIKRPHSVYETALPEFYERASFAPEMSDPSMIQGAENVA
                     KMYDVSRELQDEFAYRSHQLTAENVKNGNISQEILPITVKGEIFNTDESLKSHIPKDN
                     FGRFKPVIKGGTVTAANSCMKNDGAVLLLIMEKDMAYELGFEHGLLFKDGVTVGVDSN
                     FPGIGPVPAISNLLKRNQLTIENIEVIEINEAFSAQVVACQQALNISNTQLNIWGGAL
                     ASGHPYGASGAQLVTRLFYMFDKETMIASMGIGGGLGNAALFTRF"
     gene            4475..4840
                     /locus_tag="RPH49_002305"
     CDS             4475..4840
                     /locus_tag="RPH49_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein VraC"
                     /protein_id="HDY5125426.1"
                     /translation="MQHYSLDSNQRLNVSFSKDSVAAYYQCFNQPYRKEVPPLMCASL
                     WSKFDLFKKYANSELILTKSAINQTQKIEVDTIYVGRLEDIECRQIRNITRYTMALTL
                     TKNDQHVITVTQTFIKAMK"
     gene            4843..5112
                     /locus_tag="RPH49_002306"
     CDS             4843..5112
                     /locus_tag="RPH49_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125427.1"
                     /translation="MKFNEIWINEYLALVNDDNPIHNEIVPGQLVSQMMLMAMSLETN
                     QCQINYVKPILINENIEFIEQHEQEIIAINDDGEIKIKISLSTKK"
     gene            complement(5313..5480)
                     /locus_tag="RPH49_002307"
     CDS             complement(5313..5480)
                     /locus_tag="RPH49_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein VraX"
                     /protein_id="HDY5125428.1"
                     /translation="MIIYRQYHHEGAPVYEIITKTFQHVSIKCDDSFSDTEIFKLLSL
                     LQDDIDHMKVS"
     gene            complement(5987..6817)
                     /gene="thiD"
                     /locus_tag="RPH49_002308"
     CDS             complement(5987..6817)
                     /gene="thiD"
                     /locus_tag="RPH49_002308"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDY5125429.1"
                     /translation="MALKKVLTIAGSDTSAGAGMQADLKTFQELDTYGMVALTAIVTM
                     DKDTWSHDVTPLPMDVFEKQLETALSIGPDAIKTGMLGTEEIIKRAGEVYEASNAQYF
                     VVDPVMVCKGEDEVLNPGNTEAMIKYLLPKATVVTPNLFEAGQLSGLGKLNSIEDMKK
                     AATIIFDKGAQHVIIKGGKALDQDKSYDLYYDGQTFYQLTTDMFQQSYNHGAGCTFAA
                     ATTAYLANGKSPKEAVISAKAFVASAIKNGWKMNDFVGPVDHGAYNRIEHIDVEVTEV
                     "
     gene            7001..7657
                     /locus_tag="RPH49_002309"
     CDS             7001..7657
                     /locus_tag="RPH49_002309"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDY5125430.1"
                     /translation="MEWSQIFHDITTKHDFKVMHDFLEKEYSTAIVYPDRENIYQAFD
                     LTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTP
                     HLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
                     AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
                     "
     gene            7658..8038
                     /locus_tag="RPH49_002310"
     CDS             7658..8038
                     /locus_tag="RPH49_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5327 family protein"
                     /protein_id="HDY5125431.1"
                     /translation="MVNRETLIARIEQELVQAEQAQHDHDFEKHMYAIHILTSLYAST
                     SNTPHIGEQQMNRRIANHNQMPQSQITQPTHQVTAAEIEAMGGKVNTHSAHHHNKSYS
                     QPSNQQQRLATDDDIGNGESIFDF"
     gene            8171..8539
                     /locus_tag="RPH49_002311"
     CDS             8171..8539
                     /locus_tag="RPH49_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDY5125432.1"
                     /translation="MKLFIILGALNAMMAVGTGAFGAHGLQGKISDHYLSVWEKATTY
                     QMYHGLALLIIGVISGTTSINVNWAGWLIFAGIIFFSGSLYILVLTQIKVLGAITPIG
                     GVLFIIGWIMLIIATFKFAG"
     gene            8660..10144
                     /locus_tag="RPH49_002312"
     CDS             8660..10144
                     /locus_tag="RPH49_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDY5125433.1"
                     /translation="MEKKNKQIDRGDLKQNLSEKFVWAIAYGSCIGWGAFILPGDWIK
                     QSGPIAASIGIVIGALLMILIAVSYGALVERFPVSGGAFAFSFLSFGRYVSFFSSWFL
                     TFGYVCVVALNATAFSLLVKFLLPDVLNNGKLYTIAGWDVYITEIIIATVLLLVFMLV
                     TIRGASVSGSLQYYFCVAMVIVVLLMFFGSFFGNNFALENLQPLAEPSKGWLVSIVVI
                     VSVAPWAYVGFDNIPQTAEEFNFAPNKTFKLIVYSLLAASLTYVVMILYTGWLSTSHQ
                     SLNGQLWLTGAVTQTAFGYIGLGVLAIAIMMGIFTGLNGFLMSSSRLLFSMGRSGIMP
                     TMFSKLHSKYKTPYVAIIFLVGVSLIAPWLGRTALTWIVDMSSTGVSIAYFITCLSAA
                     KLFSYNKQSNTYAPVYKTFAIIGSFVSFIFLALLLVPGSPAALTAPSYIALLGWLIIG
                     LIFFVIRYPKLKNMDNDELSRLILNRSENEVDDMIEEPEKEKTK"
     gene            complement(10285..10737)
                     /locus_tag="RPH49_002313"
     CDS             complement(10285..10737)
                     /locus_tag="RPH49_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDY5125434.1"
                     /translation="MFWILNFIFSFLASMFFCVIFDAPRKLYLSCGFVGTCGWMVYTL
                     FFNGFNVHTIYSSFFGSLALGLLSHYMARKQKEPAIIFMVTGIIPLVPGGLAYDATKN
                     LVLLNFSTAINTMLEVTLIAGAIALGLLFADQISKLIVSGFVKSFKRL"
     gene            complement(10750..11514)
                     /locus_tag="RPH49_002314"
     CDS             complement(10750..11514)
                     /locus_tag="RPH49_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDY5125435.1"
                     /translation="MDINSEEYKQEVLIKDVVMLAARILLESGAEGTRVEDTMTRIAK
                     KLGYSESNSFVTNTVIQFTLHSESFPRIFRITSRDTNLIKISQANKISRQITNNEISL
                     AEAKTQLEKIYVAKRDSSLPFKGFAAAMIAMSFLYLQGGRLIDVLTAILAGSLGYLVT
                     EILDRKLHAQFIPEFIGSLVIGIIAVIGHTLIPTGDLATIIIAAVMPIVPGVLITNAI
                     QDLFGGHMLMFTTKSLEALVTAFGIGAGVGSVLILV"
BASE COUNT         3901 a         1796 c         2131 g         3780 t
ORIGIN      
        1 tataattatg aaacatacaa gagggagtgt atgaattcat ggattttaat aaagagaata
       61 ttaacatggt ggatgcaaag aaagctaaaa aaaccgttgt tgcaaccggt atcggtaatg
      121 caatggaatg gttcgatttt ggtgtctatg catatacaac tgcgtacatt ggagcgaact
      181 tcttctctcc agtagagaat gcagacattc gacaaatgtt gactttcgca gcattagcca
      241 ttgcgttttt attaagacca attggtggtg tcgtatttgg tattattggt gacaaatatg
      301 gacgtaaagt tgtattaaca tctacaatta ttttaatggc attttcaaca ttaaccattg
      361 gattattgcc aagctatgat caaattggac tttgggcacc aatactatta ttgcttgcaa
      421 gagtactgca aggattttca acaggtggag agtatgcggg ggcaatgaca tatgttgccg
      481 aatcatctcc agataagctt cgtaactcat taggtagtgg actagaaatt gggacattat
      541 caggttacat agctgcttca attatgattg ctgtattaac attcttttta acagatgaac
      601 aaatggcatc atttggttgg agaatcccat tcttacttgg tttattccta ggattattcg
      661 gcttatattt acgtcgtaag cttgaagaat caccagtttt cgaaaatgat gttgcaacac
      721 aaccagaacg agacaacatt aactttttac aaatcatcag attttattac aaagatatat
      781 ttgtgtgttt tgtagctgtt gtattcttca atgttacgaa ctatatggta actgcatatt
      841 taccaaccta tttagaacaa gttattaaat tagatgcaac gacaacaagt gtattaatta
      901 cttgtgtcat ggcaataatg attccattag cattaatgtt tggtaagtta gcggataaaa
      961 taggtgaaaa gaaagtattt ctaattggta ctggtgggct aacattattt agtatcatcg
     1021 catttatgtt attacattca caatcatttg ttgtaatagt aatcggtata tttatattag
     1081 gatttttctt atcaacttac gaagcgacaa tgccagggtc gttaccaacg atgttttaca
     1141 gtcatataag atatcgaact ttatcagtaa catttaatat ctctgtttcg atatttggtg
     1201 gtacgacgcc attagttgca acatggttag ttacgaaaac tggagatcca ttagcacctg
     1261 cgtattattt aacagcaatc agtgttattg gctttttagt tattacattc ttacatttaa
     1321 gtacagcagg aaaatctcta aaaggttcgt atccaaatgt agataacgag caagatagag
     1381 cttattatgc agaacaccca aaagaagcat tatggtgggt taaagaacgt aagaattaga
     1441 gattttaata aaaagtataa atcaatcgta tataagcact ttaaagctag taggttctgc
     1501 taactttaaa gtgcttttta aattgagaac tgtaattagc cgtaataaag tttttgtata
     1561 tacataaacc cccactgcaa tgattatcgc aatgggggaa agaggggact taaagcatat
     1621 gtttagcttt gaatacttaa aattctcttg ctattgaaat gttaggatgt aaatatgtct
     1681 tagagtattt tgtccaacgc aattaatatt gagactctaa ccttcaatat tattatagag
     1741 aacacaaact taaatagatt gggtgactta tttgtgtcag ttattgcgat tgcgataact
     1801 tcttttctct atatacatat agtaacgtct tatctaataa aaaacatggt actacagtat
     1861 caaatttatc tagggcttaa gtttgatttt tataataggc aggtttacct gataaaaata
     1921 cttattcatt atataatgtt aacaagatgt attttaaagt ttacattgag tgagggatat
     1981 tgatgaacgt aattttagaa cagttgaaaa cacatactca aaataaacct aatgacatag
     2041 cattacatat cgatgatgaa acaattacat atagtcaact aaatgcccgc atcactagtg
     2101 cagttgaatc tttgcagaaa tattcactta atcctgtcgt tgctattaat atgaaatcac
     2161 cggtgcaaag tattatttgt tatttagctt tgcatcgttt acataaagtg cctatgatga
     2221 tggaaggtaa atggcaaagt actatacatc gtcaattgat tgaaaaatat ggtattaaag
     2281 atgtaattgg agatacaggt ctcatgcaga gtatagattc accgatgttt attgattcaa
     2341 cgcaattaca gcactatccc aatttattac atattggttt tacttcaggg acaactggac
     2401 tgccaaaagc atattatcgt gatgaagatt catggttggc ttcttttgaa gttaatgaaa
     2461 tgttgatgtt aaaaaatgaa aatgcaatag cagcccctgg accactatcg cactcgttaa
     2521 cattatatgc gttattgttt gctttaagtt ccggtcgtac ttttatagga cagaccactt
     2581 ttcatcctga aaagttactt aatcaatgtc gtaaaatatc atcatacaaa gttgctatgt
     2641 ttcttgttcc aacgatgatt aaatcattat tgttagttta caacaatgaa catacaatcc
     2701 aatcattttt tagcagtgga gataagctgc attcttctat ttttaaaaag ataaaaaatc
     2761 aagcaaatga cataaatttg attgaatttt ttggtacatc ggaaaccagt tttatcagct
     2821 ataacttgaa tcagcaagca ccagttgaat cagtaggtgt gctatttcca aatgtggaat
     2881 tgaaaacaac ggatcacgat cacaatggta taggaactat ttgtataaaa agtaatatga
     2941 tgtttagtgg ctatgtaagt gaacaatgta taaataatga tgaatggttt gttactaatg
     3001 ataatggcta tgtaaaagag cagtatttat atttaacggg acgtcaacag gatatgttaa
     3061 ttattggtgg tcaaaatata tatccagcac atgttgaacg ccttttaacg caatcgtcga
     3121 gcattgatga agcaattatc atcggtattc caaatgagcg ttttggtcaa ataggcgtat
     3181 tgctttattc tagtgatgtg acacttacac ataaaaatgt aaaacaattt ttaaaaaaga
     3241 aagtgaaacg ctatgaaatt ccatcgatga ttcatcatgt agaaaagatg tattacactg
     3301 caagtggtaa aattgctaga gaaaaaatga tatcgatgta tttgagaggt gaattataat
     3361 atgaatcaag cagtcatagt tgcagctaaa cgaactgcat ttgggaaata tggtggcact
     3421 ttaaaacatt tagagccaga acaattgctt aaacctttat tccaacattt taaagagaag
     3481 tatccagagg taatatctaa aatagatgat gtagttttag gtaatgttgt tgggaatggt
     3541 ggcaatattg caagaaaagc attgcttgaa gcggggctta aagattcaat acctggcgtc
     3601 acaatcgatc ggcaatgtgg gtctggactt gaaagtgttc aatatgcatg tcgcatgatc
     3661 caagccggag ctggcaaggt atatattgca ggtggtgttg aaagtacaag tcgagcacct
     3721 tggaaaatca aacgaccgca ttctgtgtac gaaacagcat tacctgagtt ttatgagcgt
     3781 gcatcatttg cacctgaaat gagcgaccca tcaatgattc aaggtgctga aaatgtggcc
     3841 aagatgtatg atgtttcaag agaattacaa gatgaatttg cttatcgaag tcatcaattg
     3901 acagcggaaa atgtaaagaa tggaaatatt tctcaggaaa tattacctat aaccgttaaa
     3961 ggagaaatat tcaacactga tgaaagtcta aaatcacata ttccgaaaga taactttggc
     4021 cgatttaagc ccgtgatcaa aggtgggacc gttaccgctg cgaatagttg tatgaaaaat
     4081 gatggtgcag ttttattgct tattatggaa aaagatatgg catacgaatt aggtttcgag
     4141 catggtttat tatttaaaga tggtgttacg gtaggtgttg attctaattt tcctggcatt
     4201 ggtccagtac cagccatttc caacttacta aaaagaaatc aattaacgat agaaaatatt
     4261 gaagtcattg aaattaacga agcgttcagt gcacaggtgg ttgcctgcca acaagcttta
     4321 aatatttcaa atacgcaatt aaatatatgg ggtggtgcat tagcatcagg tcatccatac
     4381 ggtgcaagcg gtgcccaatt agtgacgcga ttattttata tgtttgacaa agagactatg
     4441 attgcatcta tggggattgg gggaggtcta ggaaatgcag cattattcac tcgattctaa
     4501 ccagcgatta aatgtgtcat tttctaagga tagtgtggct gcatattatc agtgttttaa
     4561 ccaaccttat agaaaagaag taccaccatt aatgtgtgcg tcattatggt caaaatttga
     4621 tttatttaaa aaatatgcaa atagcgaact gattttaaca aaatcagcaa ttaatcaaac
     4681 tcaaaagata gaagtagaca caatatatgt aggacgttta gaagatattg aatgccgaca
     4741 gattcgcaat atcacacgtt atacaatggc tttaacatta actaaaaatg atcaacatgt
     4801 cataacggtt acacaaactt ttattaaggc gatgaagtag agatgaagtt taatgagata
     4861 tggataaatg aatatttggc gctcgtaaat gatgataatc caatacataa tgagattgtg
     4921 ccaggacaat tagtgagtca aatgatgctg atggctatgt cattagagac aaaccagtgt
     4981 caaattaact acgttaaacc tattttaata aatgaaaata tcgaattcat tgaacaacac
     5041 gagcaagaaa ttatagcaat taatgacgat ggagagatta aaataaaaat ttctttgagc
     5101 acaaaaaaat aaccgatatt agctgcatga acgcatatta attaggagat gaaaggacag
     5161 ctaatatcag ttatgtattg ttattattat tgggaacaga gatgaatata ggttacgatt
     5221 ctttctttgc acggggatgc attaatctaa aataataata acaactatat caatgtttaa
     5281 taaattctgg attattggaa cgattagtca atttaactaa ctttcatatg atctatatcg
     5341 tcttgtaata aagagagcaa tttgaatatt tcagtatcac taaatgaatc gtcacattta
     5401 attgaaacat gctgaaacgt tttggttata atttcataaa ctggtgcgcc ttcatggtga
     5461 tactgtcgat aaataatcat aacctatatt acctcctttg ctactctatg gttatattat
     5521 aaataacatt tttatgtgtg acatcaacct taagtatcaa ctttttatca gacatagaac
     5581 gtatgattta ctaagactat ttatgtataa aagttctaaa taaatatata tttaatgagt
     5641 cgcctggcag tcatttggga aatataacat atatgattag agaggcatct atcgcaaaag
     5701 aatgataatg atagaggtat tgagcatata gatgagttta agttcatctt gaaaataaag
     5761 ggttatttag tcatagatgt agatgtatag gaaatatttg tatgtattgt tcgatatgta
     5821 tgaaattttc aataaaagct aataacgctt atatgtaact ttcaaattca aattatatac
     5881 agagcatgat gattataaaa aaataaccac atcacataaa ttgagttcat acccaattta
     5941 agtggtgtgg ctaataatgt tgatttatag atgaaccgcc taatcgttaa acctctgtta
     6001 cttcaacatc gatatgttca atacggttgt atgcaccgtg atccacagga ccaacaaaat
     6061 cattcatttt ccaaccgttt ttaatagcag aagcgacgaa agctttcgcg ctaatcacag
     6121 cttctttcgg tgacttaccg ttagctaaat atgcagttgt tgccgcagca aatgtacaac
     6181 cagcaccatg gttataactt tgttggaaca tgtctgttgt tagttgataa aatgtttgac
     6241 catcatagta taagtcatac gatttatctt gatctaaagc tttgccacct ttaatgatga
     6301 catgctgtgc gcctttatca aagataattg ttgcagcctt tttcatatct tcaattgaat
     6361 ttaatttacc taatcctgat aattgacccg cttcaaataa gtttggcgtc actaccgttg
     6421 ctttaggtag taaatattta atcatcgcct cagtatttcc aggattaagc acttcatctt
     6481 cgcctttaca aaccatgaca ggatctacta caaaatattg tgcattagat gcctcatata
     6541 cttctccagc acgtttgatt atctcctcag tacctaacat acctgtttta atagcatcag
     6601 gtccgattga taaagccgtt tcaagttgct tttcaaatac atccataggt aatggtgtga
     6661 catcgtgtga ccatgtatct ttatccatag taacgatggc agttaaagcg accataccat
     6721 acgtatctaa ttcttgaaat gtttttaaat ctgcctgcat acctgcgcca gcacttgtgt
     6781 cagaaccggc aattgttaaa actttcttta aagccattga gcttcactcc tacataataa
     6841 tattgtattc atcatatcat ttttaaccta attgaaaaat attaagcatt caatatttga
     6901 tgattgttga aatgaatcat tcatactatt gtaacttttg aaaatgtcat tcactttaga
     6961 taagtgtgat atgttaaaat atgtcctgag gtgagattga atggaatggt cgcaaatttt
     7021 tcatgacata acaacgaaac atgactttaa agttatgcat gattttttag aaaaagaata
     7081 ttcgactgca atcgtatacc ctgataggga aaatatatat caagcgtttg atttaacacc
     7141 gtttgaaaat atcaaagttg ttatattagg acaagacccg tatcatggtc caaaccaagc
     7201 acatggatta gcattttcag tgcaacctaa cgcaaaattc cctccatctt tacgtaatat
     7261 gtataaagaa ttagcagatg atattggatg tgttagacaa acaccgcatt tacaagattg
     7321 ggcaagagaa ggcgtcttgt tattgaatac agttttaacc gtaagacagg gtgaagcaaa
     7381 ttctcatcgt gatattggtt gggaaacatt tactgatgaa attattaaag cagtgtctga
     7441 ttataaagaa catgttgtct ttattttgtg ggggaaacct gcacagcaaa aaataaagct
     7501 tatcgataca tctaaacatt gtattataaa atcagtgcat cctagtccac tgtctgcata
     7561 tagaggattc tttggatcaa aaccgtattc caaagcgaat gcctatttag agtcagtagg
     7621 aaaatcacca attaattggt gtgaaagtga ggcgtagatg gtgaatagag aaactttaat
     7681 agcacgaatt gagcaagaat tagtacaagc agagcaggcg cagcatgacc atgactttga
     7741 aaaacatatg tatgccatac atatattaac atctttatat gcttcaacat caaatacacc
     7801 acatattggt gaacaacaaa tgaaccgtcg tattgctaac cataatcaaa tgccacaatc
     7861 acaaataacg cagccaactc atcaagtgac agctgctgaa attgaagcga tgggtggtaa
     7921 agtaaatacg cattcagcac atcatcataa taagtcatat tcacaacctt caaaccaaca
     7981 acaaagatta gcgacagatg atgacattgg caatggtgaa tccatatttg atttttaaaa
     8041 agcaacaatg aaacataatt acttaatagc ttgttaagta tgtaggttaa taatcaagac
     8101 acatatactt atattcgagt gttcggattt aaacatttat taatactgaa ttatataagg
     8161 agaggtagca atgaaattat ttattatttt aggtgcatta aacgcgatga tggctgtcgg
     8221 aacaggtgca tttggtgcgc atggtttaca aggaaaaata agtgatcact atttatcagt
     8281 atgggaaaaa gcaacgacgt atcaaatgta ccatggctta gcattattaa ttataggtgt
     8341 aattagtggt acaacttcaa tcaatgttaa ctgggctggc tggttaatat ttgctggtat
     8401 tattttcttt agtggatcat tatatatttt agtattaact caaattaaag ttttaggtgc
     8461 gattacgcca attggtggcg tattgttcat cattggatgg ataatgttaa tcattgcgac
     8521 attcaaattt gctggttaaa ttttaaaact ttagattacc tatgtaacta aacattaaat
     8581 ttttaataaa aataatcaag aaaaagagtt acaaactcat cttttgggta tagaatacct
     8641 tcgaggtgag tttttattta tggaaaaaaa gaataagcaa atagatagag gcgatttaaa
     8701 acaaaaccta tctgaaaagt ttgtatgggc gattgcatat ggttcatgta tcggatgggg
     8761 cgcattcatc ttaccaggag actggattaa gcagtcaggt ccgattgcag catcaattgg
     8821 tattgttatt ggtgcattat taatgatatt aattgcggtt agttatggcg cattagtaga
     8881 gagatttcca gtatcagggg gcgcgtttgc ctttagtttc ttaagtttcg gcagatatgt
     8941 gagtttcttc tcatcatggt ttttaacttt tggttatgtc tgtgtcgttg ctttaaatgc
     9001 gaccgcattc agtttactag ttaaattctt attgccagat gtcttaaata atgggaaact
     9061 atacaccatt gcgggctggg acgtttatat tacggaaatc attattgcga ccgtattact
     9121 acttgtattc atgctagtaa cgattcgtgg cgcaagtgta tctggatcat tacaatatta
     9181 tttctgtgtg gcgatggtaa tcgtcgtatt attgatgttc tttggttcat tctttggtaa
     9241 taattttgca cttgaaaatt tacaaccgtt agctgaacct agcaaaggat ggttagtgtc
     9301 tattgtggtt attgtatccg tggcaccatg ggcatatgtt ggatttgata atattccaca
     9361 aacagcagaa gagtttaact ttgcaccaaa caagacattt aagcttatcg tgtacagttt
     9421 attagcagca tcattaactt atgttgtcat gattttatac actggttggt tatcaacaag
     9481 tcatcaaagt ttaaatgggc agttgtggtt aacaggtgct gttacacaaa cagcatttgg
     9541 ttatattgga ttaggtgtat tagcaattgc aattatgatg ggtatattta ctggtttaaa
     9601 tggattcttg atgagttcaa gtcgcttgtt attttctatg ggacgttcag gtattatgcc
     9661 aacaatgttt agtaaattac atagtaaata caaaacacca tatgtcgcaa tcatattcct
     9721 agtaggtgtg tcgttaattg caccttggct aggaagaact gcattgactt ggattgtaga
     9781 tatgtcatct acaggtgtat ccattgccta ctttattaca tgtttgtctg cagcgaaatt
     9841 attcagttat aacaaacaaa gtaatacgta tgcaccggtt tacaaaacgt ttgctattat
     9901 cggctcattt gtatcattca ttttcttagc gttgttatta gtgccaggtt ctcctgcagc
     9961 actgactgca ccgtcttata ttgcattact tggatggtta atcatcggtt taatattctt
    10021 tgtgattcga tatcctaaat tgaaaaatat ggataatgat gaattaagtc gcttgatttt
    10081 aaatagaagt gaaaatgaag ttgatgatat gattgaagaa cctgaaaaag aaaaaactaa
    10141 ataataaaag aatcgcacaa tataccttct tcattcggag gcgtatcgtg cgattttttg
    10201 tattataaat tgacatttaa gacgaggcag ctgaacctta tatataattg ctaagagttt
    10261 gggctgagcc atttctaaca atatttataa tcgtttaaaa gatttcacga acccagaaac
    10321 aattaatttg gaaatttggt cggcgaataa taaacctaat gcgatggcgc ctgcaataag
    10381 tgttacttct aacattgtat ttattgctgt gctgaaattt aataagacta aatttttcgt
    10441 tgcatcgtaa gctaatccac caggtactaa tggaatgata cccgttacca taaaaatgat
    10501 ggcaggttct ttttgtttac gagccatata atgacttaac aagcctaatg ctaaactacc
    10561 aaagaaacta gagtatatag tgtgcacatt aaagccgttg aagaataagg tgtaaaccat
    10621 ccatccacat gtaccaacga aaccacatga tagatataat tttctaggtg catcaaaaat
    10681 gacgcagaag aacattgaag ctaaaaagct aaagataaag tttaagatcc aaaacatagt
    10741 ctgatactcc tatactaaaa ttaatacgct accaacgcca gcaccgatgc caaacgcagt
    10801 aaccaatgct tctaatgatt tcgttgtgaa catcaacatg tgtccaccaa ataaatcttg
    10861 tattgcgttt gttattaata caccaggaac aataggcatg actgccgcaa tgataatagt
    10921 tgccaagtca cctgttggga taagtgtatg tccaataacg gcgataatcc caataactaa
    10981 tgaaccaatg aattctggga taaactgtgc atgtaacttg cgatctaaaa tctcagtgac
    11041 taggtatcct agactacctg ctaatatcgc agttaaaaca tcaatcaatc taccaccttg
    11101 taaatataag aaactcattg caatcattgc tgcagcaaaa cctttaaagg gaagactgct
    11161 gtcacgctta gcaacatata ttttttcaag ttgcgttttt gcttcggcta aagaaatttc
    11221 attgtttgta atttgacgcg aaattttatt agcttgagaa atttttatta agtttgtatc
    11281 tcgagaggta attctaaata ttctaggaaa cgattccgaa tgtaacgtaa actggatgac
    11341 agtgtttgta acaaagctgt tactttcact gtaaccaagt ttttttgcaa tacgtgtcat
    11401 ggtatcttct acacgcgtac cttctgcacc agattctaat agtatgcgag cagcaagcat
    11461 gacaacgtct ttgataagta cctcttgttt gtattcttct gaatttatgt ccatttcatc
    11521 accattgttt ataagaattt aatactcatt atagtttata cactataaaa taaccacatg
    11581 agctttttga taagttgtta ttgatttt
//
LOCUS       DAPSKH010000072        11394 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPSKH010000072 DAPSKH010000000
VERSION     DAPSKH010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 11394)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11394)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11394
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.072"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(402..1154)
                     /locus_tag="RPH49_002315"
     CDS             complement(402..1154)
                     /locus_tag="RPH49_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-dependent peroxidase"
                     /protein_id="HDY5125436.1"
                     /translation="MSQAAETLDGWYSLHLFYAVDWASLRLVPKNERDALVTEFQSFL
                     ENTATVRSSKSGDQAIYNITGQKADLLLWFLRPEMKSLNHIENEFNKLRIADFLIPTY
                     SYVSVIELSNYLAGKSDEDPYENPHIKARLYPELPHSDYICFYPMNKRRNETYNWYML
                     TMEERQKLMYDHGMIGRKYAGKIKQFITGSVGFDDFEWGVTLFSDDVLQFKKIVYEMR
                     FDETTARYGEFGSFFVGHIINTNEFDQFFAIS"
     gene            1322..2308
                     /gene="pta"
                     /locus_tag="RPH49_002316"
     CDS             1322..2308
                     /gene="pta"
                     /locus_tag="RPH49_002316"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDY5125437.1"
                     /translation="MADLLNVLKDKLSGKNVKIVLPEGEDERVLTAATQLQATDYVTP
                     IVLGDETKVQSLAQKLNLDISNIELINPATSEFKAELVQSFVERRKGKATEEQAQELL
                     NNVNYFGTMLVYAGKADGLVSGAAHSTGDTVRPALQIIKTKPGVSRTSGIFFMIKGDE
                     QYIFGDCAINPELDSQGLAEIAVESAKSALSFGMDPKVAMLSFSTKGSAKSDDVTKVQ
                     EAVKLAQQKAEEEKLEAIIDGEFQFDAAIVPGVAEKKAPGAKLQGDANVFVFPSLEAG
                     NIGYKIAQRLGGYDAVGPVLQGLNSPVNDLSRGCSIEDVYNLSIITAAQALQ"
     gene            2311..3147
                     /locus_tag="RPH49_002317"
     CDS             2311..3147
                     /locus_tag="RPH49_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014532577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDY5125438.1"
                     /translation="MDLASKYFNGVNWRYIDHSSGLEPMQSFAFDDTFCESVGKDISD
                     NVVRTWIHQHTVILGIHDSRLPFLKDGIDYLTNEIGYNAIVRNSGGLGVVLDQGVLNI
                     SLMFKGQTETTIDEAFTVMYLLISKMFEDENVDIDTMEIEHSYCPGKFDLSIDGKKFA
                     GISQRRVRGGIAVQIYLCVEGSGSERALMMQTFYEHALKGEVTKFKYPEIEPSCMASL
                     ETLLNKTITVQDVMFLLLYAIKDLGGVLNMTPITQEEWQRYDTYFDKMIERNKKMIDQ
                     MQ"
     gene            3734..4654
                     /gene="mvk"
                     /locus_tag="RPH49_002318"
     CDS             3734..4654
                     /gene="mvk"
                     /locus_tag="RPH49_002318"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDY5125439.1"
                     /translation="MTRKGYGESTGKIILIGEHAVTFGEPAIAVPFNAGKIKVLIEAL
                     ESGNYSSIKSDVYDGMLYDAPDHLKSLVNRFVELNNITEPLAVTIQTNLPPSRGLGSS
                     AAVAVAFVRASYDFLGKSLTKEELIEKANWAEQIAHGKPSGIDTQTIVSGKPVWFQKG
                     HAETLKTLSLDGYMVVIDTGVKGSTRQAVEDVHKLCEDPQYMSHVKHIGKLVLRASDV
                     IEHHNFEALADIFNECHADLKALTVSHDKIEQLMKIGKENGAIAGKLTGAGRGGSMLL
                     LAKDLPTAKNIVKAVEKAGAAHTWIENLGG"
     gene            4659..5642
                     /gene="mvaD"
                     /locus_tag="RPH49_002319"
     CDS             4659..5642
                     /gene="mvaD"
                     /locus_tag="RPH49_002319"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDY5125440.1"
                     /translation="MIKSGKARAHTNIALIKYWGKKDEALIIPMNNSISVTLEKFYTE
                     TKVTFNDQLTQDQFWLNGEKVSGKELEKISKYMDIVRNRAGIDWYAEIESDNFVPTAA
                     GLASSASAYAALAAACNQALDMQLSDKDLSRLARIGSGSASRSIYGGFAEWEKGYSDE
                     TSYAVPLESNHFEDDLAMIFVVINQHSKKVPSRYGMSLTRNTSRFYQYWLDHIDEDLA
                     EAKAAIQDKDFKRLGEVIEENGLRMHATNLGSTPPFTYLVQESYDVMALVHECREAGY
                     PCYFTMDAGPNVKILVEKKNKQQIIDKLLTQFDNNQIIDSDIIATGIEIIE"
     gene            5655..6731
                     /locus_tag="RPH49_002320"
     CDS             5655..6731
                     /locus_tag="RPH49_002320"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDY5125441.1"
                     /translation="MIQVKAPGKLYIAGEYAVTEPGYKSVLIALDRFVTATIEEADQY
                     KGTIHSKALHHNPVTFSRDEDSIVISDPHAAKQLNYVVTAIEIFEQYAKSCDIAMKHF
                     HLTIDSNLDDSNGHKYGLGSSAAVLVSVIKVLNEFYDMKLSNLYIYKLAVIANMKLQS
                     LSSCGDIAVSVYSGWLAYSTFDHEWVKHQIEDTTVEEVLIKNWPGLHIEPLQAPENME
                     VLIGWTGSPASSPHFVSEVKRLKSDPSFYGDFLEDSHRCVEKLIHAFKTNNIKGVQKM
                     VRQNRTIIQRMDKEATVDIETEKLKYLCDIAEKYHGASKTSGAGGGDCGITIINKDVD
                     KEKIYDEWTKHGIKPLKFNIYHGQ"
     gene            6908..7249
                     /locus_tag="RPH49_002321"
     CDS             6908..7249
                     /locus_tag="RPH49_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1450 domain-containing protein"
                     /protein_id="HDY5125442.1"
                     /translation="MKNTFLICDECQAVNIRTLQKKLEKLDPDAEIVIGCQSYCGPGR
                     RKTFTFVNNRPLAALTEEELIEKVSQQLKKPRDSEEEERLRKRHEERKRRKEEQDRKL
                     KEKLEKRKAQQ"
     gene            complement(7301..8623)
                     /locus_tag="RPH49_002322"
     CDS             complement(7301..8623)
                     /locus_tag="RPH49_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDY5125443.1"
                     /translation="MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCI
                     NIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFK
                     SNTEVNLLDQHGDIADSITAPHIIINTGATSVIPNIKDLDQAKHVFDSTGLLNINYQP
                     KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIAL
                     HTNVETTELSSDDHHTTVRTNVGNFEADAVLLAIGRKPNTDLALENTDIELGDRGEIK
                     VNAHLQTTVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVF
                     IDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILG
                     ATLYGKQSEELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF"
     gene            complement(8610..9050)
                     /locus_tag="RPH49_002323"
     CDS             complement(8610..9050)
                     /locus_tag="RPH49_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006189740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDY5125444.1"
                     /translation="MNLEFNIAVHVLAFLTKHHSEKFNSSSLAELTCLNPVQLRRVTT
                     QLVDLKMINTIRGKDGGYLANDQSADVSLATLYKHFVLEKKHHTRLFTGDEGSHCQIA
                     RNIATTMSHYQQDEQNIIINFYNGKTIKDVIEDIQKEDLCHENI"
     gene            9108..9209
                     /locus_tag="RPH49_002324"
     CDS             9108..9209
                     /locus_tag="RPH49_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125445.1"
                     /translation="MCQYLCLKSVELGVVIVMIYCLKVVALTVRLHN"
     gene            9674..11068
                     /locus_tag="RPH49_002325"
     CDS             9674..11068
                     /locus_tag="RPH49_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125446.1"
                     /translation="MSIDMYLDRSRNQASSVGNLSQTMNSNYDALEKAITQFINDDAL
                     KGKAYTSAKQFFSTVLIPLSTSMKTLSDLTKQACDNFVSRYTSEVDSISLKESELEED
                     IRSLSQQITRYENLTNNLKKHASDNQQAISSNQQIIQTLGQQKHELEEKLRKLREFNQ
                     KSPEIFKEVEEFQKIVQQGLTQAQNFWNFSTNQFNIPSGKELDWAKASHEKYLKVAMG
                     KIEHKAEKETLNKADFAVIKAYAKEHPEDDIPKSIMKYINDNKDSIKRDIGLDITSTL
                     LEQGGINASKFGVFINTAGGVKGPAGPNSFVEVKRTSGNVFIENGSKFAKGGKYLGKG
                     VAGVGFGIGMYDDLANDDKTFGEALSHNGMTLAAGSVAAFGVAALVSNPVGWAVVGIL
                     TAGIIGSIVSDYLYQNNYFGIKDKVDWAGHKIDEGIDAVNKTAEKAVDSVGNTIGDAT
                     KSISNHINPMKWSW"
     gene            11069..>11394
                     /locus_tag="RPH49_002326"
     CDS             11069..>11394
                     /locus_tag="RPH49_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDY5125447.1"
                     /translation="MLLCESKVINKNPKYRIIKYESEYLMIDLASNWIVFFFPFINWL
                     IPKTYVKITKNDYEKLNIVKPVKNKSIGWTIFAGIVLLGGTVRRNTYLFDFQLEKLIV
                     WSSCFI"
BASE COUNT         4019 a         1617 c         2174 g         3584 t
ORIGIN      
        1 gttaaaattc tcttgaagta taaaaaggaa aaattattga aaaaaattcg acaaaaatat
       61 gtttcaaata tttcaaatag gttaaaataa tattagttaa ccattacaaa aattgtatag
      121 agtagcgact gtataatttc tattgaggtt aacgtttata tgtagtgata gtagttaaag
      181 ttctcccaag gaagactact cgggtacact ttgctatgag caaagtgtac tttgttattg
      241 ataatacatt agcacatata tataagttta aacatacaga tttcaactat ttaccaaatc
      301 acgtcttatg tatacgggaa tatactgaag ataaacgaaa aattccaagc ttaaaccgat
      361 aagcttggaa ttttttatta atttataaac gtaccaatgt attaagaaat cgcaaagaat
      421 tgatcgaatt cgtttgtgtt aataatatgt cctacaaaga aactaccgaa ttcaccgtat
      481 cgtgctgttg tttcatcaaa gcgcatttcg tatacaattt ttttgaattg taatacgtca
      541 tctgagaaca atgttacgcc ccattcgaaa tcatcaaacc ctacagaacc agtaataaat
      601 tgtttgattt tgccagcata ttttctacca atcataccat ggtcatacat taatttttgg
      661 cgttcttcca tagttaacat gtaccagtta taagtttcat tacgacgttt gttcattgga
      721 tagaaacaaa tataatcaga atgtggtaat tctgggtata atcttgcttt gatatgaggg
      781 ttctcataag gatcttcatc agatttacca gctaaataat tgctcaattc aatgactgaa
      841 acatatgaat atgtagggat taggaagtca gcaatgcgca atttgttaaa ttcattttca
      901 atatgattta aagacttcat ttcaggacgt aagaaccata ataacaaatc tgctttttga
      961 ccagttatat tataaatagc ttgatcacca gattttgatg atcttacagt tgctgtattt
     1021 tctaaaaatg attgaaattc agtgacaagt gcatcgcgtt cgttctttgg aactagacgt
     1081 aatgatgccc aatcaactgc ataaaataaa tgtagactat accaaccatc taatgtttcg
     1141 gctgcttgac tcatgtttat cgctcctttt caaaaatcat cagttcttta taaattttat
     1201 cataaagcaa aggggtaacg ataaaattat gattacaaat tggtgacgtg gcattatgaa
     1261 ataaaatggc gtataattat accgtgaatg attaataaga tttatattac aggaggacat
     1321 tatggctgat ttattaaatg tattaaaaga caaactttct ggtaaaaacg ttaaaatcgt
     1381 attacctgaa ggagaggacg agcgtgttct aacagctgca acacaattac aagcaacaga
     1441 ttatgttaca ccaatcgtgt taggtgatga gactaaggtt caatctttag cgcaaaaact
     1501 taatcttgat atttctaata ttgaattaat taatcctgcg acaagtgaat ttaaagctga
     1561 attagtccaa tcatttgttg aacgacgtaa aggtaaagcg actgaagaac aagcgcaaga
     1621 attattaaac aatgtgaact acttcggtac aatgcttgtt tatgctggta aagcagatgg
     1681 tttagttagt ggtgcagcac attcaacagg agacactgtg cgtccagctt tacaaatcat
     1741 caaaacgaaa ccaggtgtat caagaacatc aggtatcttc tttatgatta aaggtgatga
     1801 acaatacatc tttggtgatt gtgcaatcaa tccagaactt gattcacaag gacttgcaga
     1861 aattgcagta gaaagtgcaa aatcagcatt aagctttggc atggatccaa aagttgcaat
     1921 gttaagcttt tcaacaaaag ggtctgctaa atcagacgac gtgacaaaag ttcaagaagc
     1981 tgtcaaatta gcacaacaaa aagctgaaga agaaaaatta gaagcaatca ttgatggaga
     2041 attccaattt gatgctgcga ttgtaccagg tgttgctgag aaaaaagcgc caggtgctaa
     2101 attacaaggt gatgcaaatg tctttgtatt cccaagttta gaagctggta atattggtta
     2161 caaaattgca caacgtttag gtggatatga tgcagttggt ccagtattac aaggtttaaa
     2221 ttctccagta aatgacttat cacgtggctg ttcaattgaa gatgtataca atctttcaat
     2281 tatcacagca gcgcaagcct tacaataacg atggatttag cgagtaaata ttttaatggc
     2341 gtcaactggc gatatatcga tcattcttct ggattagagc ctatgcaatc tttcgcattc
     2401 gatgatacat tttgtgaaag tgtgggcaaa gatatatcag ataatgttgt gcgtacttgg
     2461 attcatcaac atactgttat tcttggtatt catgattcaa gattgccgtt tttaaaagat
     2521 ggcattgatt atttaacgaa tgagattggt tataatgcca ttgttagaaa ttctggtggc
     2581 ttaggtgtcg ttctagatca aggtgtatta aatatatcgc tgatgttcaa aggacaaaca
     2641 gaaacaacga ttgatgaagc gtttactgtg atgtatcttt taattagcaa aatgttcgaa
     2701 gatgagaatg ttgatattga tacgatggaa attgaacatt cttattgccc aggaaaattt
     2761 gacttaagta tcgatggtaa aaaatttgca ggcatatcgc aacgaagagt tagaggcggt
     2821 attgctgtac aaatttatct ttgtgttgaa ggctctggtt cagaacgtgc attgatgatg
     2881 caaacatttt atgaacatgc tttaaaaggt gaagtgacta aatttaaata tcctgaaatt
     2941 gaaccatctt gtatggcctc attagagaca ttgcttaaca aaacgattac tgttcaagat
     3001 gtaatgtttt tactattata tgcaatcaaa gatcttggcg gtgtattaaa tatgacgccc
     3061 attactcaag aagaatggca aagatacgat acgtattttg ataaaatgat tgaaagaaac
     3121 aagaaaatga tagaccaaat gcaatagtta aatatttaac agcccctttc aagttatcgt
     3181 ttggggctgt tatttttgaa agtatccata aatagcataa atatgttatt ggcctaatat
     3241 ttaaattgaa catcattaaa ttaaaagtaa tgatatgatt gaaataataa atttaataag
     3301 aaaatttcat gttttacgta ttaaatagat tgagaatagg gtatatataa tgcgtatgac
     3361 tatgaaagaa acggccttct attgaaatgt tctaatactt tagtagtaaa tctatatatt
     3421 ccaattatta tttgtagtat tatagttaga gtggaaaatt ataaattgta gggctatttt
     3481 ataaaaagat aaagaatctg aaatatcact cgataagatt taaactttga agtaaacgaa
     3541 agttagtttt atactaatca agttaagtca aatataaatt caaaataaag attatacata
     3601 atatgaataa tgtgagataa agactgcaat gaaatttgac gcgaatgcgt atgcaactta
     3661 gaatatgatg tcttttacta ataaataaaa ataatgaatc aagtatagga taaatataaa
     3721 aggtgatatt gacatgacaa gaaaaggata tggggaatcg acaggtaaga ttattttaat
     3781 aggagaacat gctgttacat ttggagagcc tgctattgca gtaccgttta acgcaggtaa
     3841 aatcaaagtt ttaatagaag ccttagagag cgggaactat tcgtctatta aaagcgatgt
     3901 ttacgatggt atgttatatg atgcgcctga ccatcttaag tctttggtga accgttttgt
     3961 agaattaaat aatattacag agccgctagc agtaacgatc caaacgaatt taccaccatc
     4021 acgtggatta ggatcgagtg cagctgtcgc ggttgctttt gttcgtgcaa gttatgattt
     4081 tttagggaaa tcattaacga aagaagaact cattgaaaag gctaattggg cagagcaaat
     4141 tgcacatggt aaaccaagtg gtattgatac gcaaacgatt gtatcaggca aaccagtttg
     4201 gttccaaaaa ggtcatgctg aaacattgaa aacgttaagt ttagacggct atatggttgt
     4261 tattgatact ggtgtgaaag gttcaacaag acaagcggta gaagatgttc ataaactttg
     4321 tgaggatcct cagtacatgt cacatgtaaa acatatcggt aagttagttt tacgtgcgag
     4381 tgatgtgatt gaacatcata actttgaagc cttagcggat atttttaatg aatgtcatgc
     4441 ggatttaaag gcgttgacag ttagtcatga taaaatagaa caattaatga aaattggtaa
     4501 agaaaatggt gcgattgctg gaaaacttac tggtgctggt cgtggcggaa gtatgttatt
     4561 gcttgccaaa gatttaccaa cagcgaaaaa tattgtaaaa gctgtagaaa aagctggtgc
     4621 agcacatact tggattgaga atttaggagg ttaatgcgtt gattaaaagt ggcaaagcac
     4681 gtgcacatac gaatattgca cttataaaat attggggtaa aaaagatgaa gcactaatca
     4741 ttccaatgaa taatagcata tctgttacat tagaaaaatt ttacactgaa acgaaagtca
     4801 cttttaacga ccagttaaca caggatcaat tttggttgaa tggtgaaaag gttagtggca
     4861 aagaattaga gaaaatttca aaatatatgg atattgtcag aaatagagct ggcatcgatt
     4921 ggtatgcaga aattgaaagc gacaattttg taccaacagc agcagggttg gcttcatcgg
     4981 caagcgcata tgcagcttta gcagcagctt gtaatcaagc gctagacatg cagctgtcag
     5041 ataaggattt atcgagattg gcgcgaattg gttcgggttc tgcgtcgcgt agtatttatg
     5101 gtggatttgc agaatgggaa aaagggtata gtgatgagac gtcatatgcc gttccacttg
     5161 aatcgaatca ttttgaagat gaccttgcca tgatatttgt tgtgattaat caacattcta
     5221 aaaaggtacc tagtcgatat ggtatgtcat tgacacgaaa cacatcaagg ttttatcaat
     5281 attggttaga tcatattgat gaagatttag ctgaagcaaa agcagcgatt caagacaaag
     5341 attttaaacg tcttggtgaa gtaattgaag aaaatggttt gcgtatgcat gccacgaatc
     5401 taggatcaac accgccgttc acatatcttg tgcaagaaag ttatgatgta atggcgctcg
     5461 ttcacgaatg ccgagaagcg ggatatccgt gttattttac gatggatgcg ggtcctaatg
     5521 tgaaaatact tgtagaaaag aaaaacaagc aacagattat agataaatta ttaacacagt
     5581 ttgataataa ccaaattatt gatagtgaca ttattgccac aggaattgaa ataattgagt
     5641 aaggaagaga taaaatgatt caggtcaaag cacccggaaa actttatatt gctggagaat
     5701 atgctgtaac agaaccagga tataaatctg tacttattgc gttagatcgt tttgtaactg
     5761 ctactattga agaagcagac caatataaag gtaccattca ttcaaaagca ttacatcata
     5821 acccagttac atttagtaga gatgaagata gtattgtcat ttcagatcca catgcagcaa
     5881 aacaattaaa ttatgtggtc acagctattg aaatatttga acaatacgcg aaaagttgcg
     5941 atatagcgat gaagcatttt catctgacta ttgatagtaa tttagatgat tcaaatggtc
     6001 ataaatatgg attaggttca agtgcagcag tacttgtgtc agttataaaa gtattaaatg
     6061 aattttatga tatgaagtta tctaatttat acatttataa actagcagtg attgcaaata
     6121 tgaagttaca aagtttaagt tcatgcggag atattgctgt gagtgtatat agtggatggc
     6181 tagcgtatag tacttttgat catgaatggg ttaagcatca aattgaagat actacggttg
     6241 aagaagtttt aatcaaaaac tggcctggat tgcacatcga accattacaa gcacctgaaa
     6301 atatggaagt acttatcggt tggactggct caccggcgtc atcaccacac tttgttagcg
     6361 aagtgaaacg tttgaaatca gatccttcat tttacggtga cttcttagaa gattcacatc
     6421 gttgtgttga aaagcttatt catgctttta aaacaaataa cattaaaggt gtgcaaaaga
     6481 tggtgcgtca gaatcgtaca attattcaac gtatggataa agaagctaca gttgatatag
     6541 aaactgaaaa gctaaaatat ttgtgtgata ttgctgaaaa gtatcacggc gcatctaaaa
     6601 catcaggcgc tggtggtgga gactgtggta ttacaattat caataaagat gtagataaag
     6661 aaaaaattta tgatgaatgg acaaaacatg gtattaaacc attaaaattt aatatttatc
     6721 atgggcaata aatgatttga taggggagca atcatctaat ttaattagaa gataaatgct
     6781 ccatttttta ttgccagccg tgttacgtat cttgaaaaaa atattaaaaa gagtaaaata
     6841 gatagagtta acgaaaaaat taatgaaatc gacgatatag atatgataaa gaaaggtggg
     6901 tagcaatatg aaaaatacat tccttatttg tgatgaatgt caggcagtca atataagaac
     6961 gttacaaaag aagttggaaa aattagatcc cgatgctgaa atcgtgatag gttgtcaatc
     7021 ttattgtgga cctggacgcc gaaaaacatt cacttttgtt aataaccgcc cactggctgc
     7081 gcttactgaa gaagaattaa tcgaaaaagt ttctcaacaa ttaaagaaac cacgtgattc
     7141 tgaagaagaa gagcgtttaa gaaaacgaca tgaagaacgt aaacgtcgta aagaagaaca
     7201 agatagaaag cttaaagaaa aattagaaaa gcgaaaagca caacaataaa acctgatggc
     7261 agcatcattc aatgcgtgcc accaggtttt tatgttttgt ctagaaatta aataaatcat
     7321 taaatgattc ggccatcgta ggatgtgtat aaatattatc tcgtaatacg gtatatggaa
     7381 tgttttgatc aatcgcaagt ttaattatat taattaattc ttcagattgc ttaccatata
     7441 atgtagcacc taaaatcata ttattttcat tattaatgac tactttaaat aaaccccttg
     7501 gatcattgtt aattttgtga cgaggtattg cacttactaa aagttggtgt tcagtgtaat
     7561 cataatgttg agcggctgct tctttactag ttaatccaac acgtgataat ggtggatcta
     7621 taaatactgt ataaggcacg ctgcctctat tgtcagtcgt acgtgactga ttaccatata
     7681 acgctgattt gataattcga taatcatcta aagatatata cgtaaattga agtccgcctt
     7741 taacatcacc tgcagcataa atatgcggca cagttgtttg aagatgagca ttgactttaa
     7801 tttcgcctct gtcgcctaat tcgatatcag tattttctaa agctaaatct gtattcggtt
     7861 tgcgtccgat agccaaaagt actgcatcag cctcaaagtt gccaacgtta gtacggactg
     7921 ttgtatgatg atcgtcagat gacaattcag tcgtttcaac atttgtatgc aatgcaatgc
     7981 ctttattttc taagtcagta atagcatgtg caacgacatc ttgatcttcg cgtggcataa
     8041 atgattcacc acgttctaat actgttacct tactacctaa attcgcaaac attgaagcaa
     8101 attctaaggc gatataaccg ccacctacaa taacgaggtg cttaggttga tagttaatgt
     8161 ttaataaacc tgttgaatcg aagacatgtt tagcttgatc aaggtctttt atgttaggaa
     8221 tgacagaggt agcaccggta ttaataatga tatgaggtgc agtaatacta tcggcgatat
     8281 cgccatgctg atctaataaa ttcacttcag tattagattt aaactgcgct ttaaaatcca
     8341 gtacatcaat gttgttatcg tctgctaata agtggtaatt tttattgttt agcgcattga
     8401 caacatcgtt tttacgatta taacttgctt caaaggattt gccttctaat ccatcatgta
     8461 caagtgtctt cgaaggtata catcctatat tgatacaagt gcctccatac attttcgaag
     8521 attgttcgat aactgcgacg tgttgacctg ttgatgcagc gtatttcgct aaagttttac
     8581 cagctttccc aaatcctatt acaattaaat catatgtttt catgacataa atcctccttt
     8641 tgaatgtctt caatgacatc tttgattgtt tttccattat aaaaattaat aatgatattc
     8701 tgttcgtctt gctgataatg tgacatggta gttgcaatat tacgagcaat ttgacagtga
     8761 ctgccttcgt cgccagtaaa tagacgtgtg tggtgttttt tctctaagac aaaatgttta
     8821 tataatgttg ctagagagac atcagcactt tgatcatttg ctaaatatcc accatcttta
     8881 ccccgtattg tgttaatcat ttttaaatcg acaagttgag tcgtcacgcg tcgtaattga
     8941 acaggattta aacaagttaa ttcagctaat gaactactat tgaatttttc tgaatgatgc
     9001 ttagttaaaa aagctaatac atgcacggca atgttaaatt ctaaattcaa tgtttctcac
     9061 ctcatatttg taactgtatt agttacaatt aaaaatcatt ttgctcaatg tgtcaatact
     9121 tatgtttgaa aagtgttgaa ttaggtgtgg ttattgtgat gatttattgt ttgaaagttg
     9181 ttgcattaac ggtgagattg cacaattgaa attttagtta tgtatgaact gttaaatatg
     9241 aaatgaatat tgaaatgagg gcaataaaat tttgaatgat gatgttgtgt gattttgtaa
     9301 acttattcgt attttagata ttttttgata tttcgcatga tgaggaagta ttttcaacaa
     9361 ctggtgacat atttaaatcg taaatatatt ttgagatatt aatatatatt agattaagga
     9421 tgttgtcgca ataaaattaa aatattgaaa gataattttt attgattaat tgtgaatata
     9481 caaagacacc attatatcca tatgctaaaa taagaaaaaa ggcgacatgt tatctcaatt
     9541 tacctgcatc tagacccctt tacataagaa ataatcatcg ctgagtttta aaattttaca
     9601 actttataga tgtaaaaagc atttaatttt aaatagtttg aaaatcatat atttttgaaa
     9661 aaggagcatg ccgatgagta ttgacatgta tttagacaga tctcgaaacc aagcttcaag
     9721 tgtgggtaat ttgagtcaaa caatgaattc aaattatgat gcgttggaaa aagcaattac
     9781 tcaatttatc aatgatgatg cgcttaaagg taaagcgtat acgtcagcta aacaattttt
     9841 tagtacggtg ttaattccat tatcaacaag tatgaaaaca ttgagtgatt taacgaagca
     9901 agcttgcgat aattttgtgt cacgttatac gagtgaggtt gatagcatat ctttaaaaga
     9961 atcagagctt gaagaagata tcagatcatt aagtcaacaa attacgcgat atgaaaattt
    10021 aactaacaat ttgaaaaagc atgcttccga taatcagcaa gccatttcat cgaaccaaca
    10081 aataatacaa acattaggtc aacaaaaaca tgaattagaa gagaagctac gcaaattgcg
    10141 tgagtttaat caaaaatcac cagaaatatt taaagaagtt gaagaatttc aaaaaattgt
    10201 ccaacaagga cttacccaag cgcaaaattt ttggaacttt tcaacaaatc aatttaacat
    10261 tccttcaggt aaagaacttg attgggccaa agcaagtcat gaaaaatatt tgaaagttgc
    10321 tatggggaaa attgaacata aagcagagaa agaaacttta aataaagcag actttgctgt
    10381 tataaaggca tatgccaaag aacatccaga agacgatatc ccgaaaagta taatgaaata
    10441 tataaatgac aataaagata gtattaaacg agatatagga ttagatatta cgtcaacact
    10501 tttagagcaa ggcggtataa atgcaagtaa attcggtgta tttatcaata cagcaggtgg
    10561 agtgaaaggc ccagccggtc caaattcatt tgtggaagtc aaacgtacat caggtaatgt
    10621 gtttatagaa aatggtagta aatttgctaa aggtggaaaa tatctaggta aaggtgttgc
    10681 aggtgtagga tttggtatag gtatgtatga tgaccttgca aatgatgata aaacatttgg
    10741 ggaggcgttg tcgcataatg gtatgacgct tgcagctgga tctgttgcag catttggtgt
    10801 agcggcttta gtaagtaatc cagtcggttg ggctgtggta ggtattttaa cagcaggtat
    10861 tattggatct attgtttctg attatcttta tcaaaataat tattttggca taaaagataa
    10921 agtggactgg gcaggacata aaatagacga gggtattgat gctgtaaaca aaactgcaga
    10981 aaaagctgta gatagtgttg gtaataccat tggtgatgcc acaaaaagta ttagtaatca
    11041 tattaatcct atgaaatgga gttggtaaat attgctttgc gaatctaaag ttattaataa
    11101 aaatcctaaa tatcgaataa tcaaatacga aagtgaatac ttaatgattg atttagcaag
    11161 taattggatt gttttcttct ttccatttat taactggctc ataccgaaaa catatgtcaa
    11221 aatcactaag aatgattatg aaaaattaaa tattgtcaaa ccagttaaaa ataaatcgat
    11281 aggatggact atattcgcgg gtattgtgtt acttggtggt actgtaagaa gaaatactta
    11341 tttatttgat tttcaattag aaaaactaat tgtttggagc agctgtttta ttag
//
LOCUS       DAPSKH010000073        10810 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPSKH010000073 DAPSKH010000000
VERSION     DAPSKH010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10810
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.073"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            67..702
                     /locus_tag="RPH49_002327"
     CDS             67..702
                     /locus_tag="RPH49_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDY5125448.1"
                     /translation="MKLNNYSLKVKNKQLVDNCDLNFYLGQINHIVGKNGVGKSLLAK
                     DFLLNNSGNIPKSISQNVTLISSSSNIPNDITKDFLLSLLKSKFENNRQTFDKIYNIL
                     NIEAIPSNVLLKNLSDGQKQKLKLLSFLLEDHDLIILDEVTNALDKKTVNEIYEFLND
                     FIQSHQTKTIINITHNLSDLSALPGKYFIFKDLQIEEYQSKEEVINDYINL"
     gene            708..1439
                     /locus_tag="RPH49_002328"
     CDS             708..1439
                     /locus_tag="RPH49_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="HDY5125449.1"
                     /translation="MSTLKLEFKKSISNKIIYTLGVLFIFLFLLGYFLPIGIDKVKSL
                     SYSQFFFSSYTVATQLGFLLFSFVIAYFINKEYSNKNILFYKLIGDNIFTFFYKKVAV
                     LFFECLVFIILSITIISIIYSDFSHYLLLIILFSLVILQYILVVGTISMVSPNILISL
                     GISIVYWIGSVILVAINKNIFGIVAPFEASNTMYRAVEKILNNESTFICPTEIINTVS
                     FFVLLFIVNTIVLLLSRKRWLKIGM"
     gene            complement(1601..2221)
                     /gene="srtA"
                     /locus_tag="RPH49_002329"
     CDS             complement(1601..2221)
                     /gene="srtA"
                     /locus_tag="RPH49_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase SrtA"
                     /protein_id="HDY5125450.1"
                     /translation="MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQ
                     YDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVS
                     FAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRD
                     VKPTDVEVLDEQKGKDKQLTLITCDDYNEKTGVWETRKIFVATEVK"
     gene            2415..2906
                     /locus_tag="RPH49_002330"
     CDS             2415..2906
                     /locus_tag="RPH49_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDY5125451.1"
                     /translation="MIRCAKKEDLNAILVIYNDAIINTTAVYTYEPQTIDERVAWFET
                     KQRKHEPIFVFEENGSVLGFATFGSFRPWPAYLYTIEHSIYVDASARGKGIASQLLHH
                     LIVEAKAKGYRALVAGIDASNKASIQLHQKFAFKHAGTLTNVGFKFNQWLDLAFYELD
                     LQD"
     gene            complement(3055..3225)
                     /locus_tag="RPH49_002331"
     CDS             complement(3055..3225)
                     /locus_tag="RPH49_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125452.1"
                     /translation="MLRLSIIFIAFIINTTITYGYTTEGTWVNLLFKSLSLSMIIVFM
                     FYYIRFVIEKKR"
     gene            complement(3287..3385)
                     /locus_tag="RPH49_002332"
     CDS             complement(3287..3385)
                     /locus_tag="RPH49_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125453.1"
                     /translation="MIKKKHLSGSLVPDRCFLIISEEVEKFMGNTC"
     gene            complement(3404..4303)
                     /gene="sdaAA"
                     /locus_tag="RPH49_002333"
     CDS             complement(3404..4303)
                     /gene="sdaAA"
                     /locus_tag="RPH49_002333"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDY5125454.1"
                     /translation="MFDSIRETIDYAVENNISFADIMVKEEMELSGKSRDEVRAQMKQ
                     NLDVMRDAVIKGTTGDGVESVTGYTGHDAAKLRDYNETHHALSGYEMIDAVKGAIATN
                     EVNAAMGIICATPTAGSSGTIPGALFKLEKTHDLTEEQMIDFLFTSALFGRVVANNAS
                     VAGATGGCQAEVGSASAMAAAAAVAIFGGSPEASGHAMALAISNLLGLVCDPVAGLVE
                     IPCVMRNAIGSGNALISADLALAGIESRIPVDEVIEAMDKVGRNLPASLRETGLGGLA
                     GTPTGEAIKRKIFGTAEDMVKNN"
     gene            complement(4317..4997)
                     /gene="sdaAB"
                     /locus_tag="RPH49_002334"
     CDS             complement(4317..4997)
                     /gene="sdaAB"
                     /locus_tag="RPH49_002334"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDY5125455.1"
                     /translation="MAKSYDYQSAFDIIGPVMMGPSSSHTAGAVKIGNSARAILGDIP
                     KNIEIHYYESFAQTHQGHGTDVAIVGGAMGYSTFDNRIKSSLEIAADDGIKIDIIEEE
                     GDSIGQHPNCAYIKSSRNDGRYIEIIGISIGGGTIKIKGIHINGLEVDLNHGLPILVV
                     DGNMTKAQVNHFINDINDMKLDCKDEFIKIDEDKCLVVIPLNKAISESTLNTIKEKYS
                     DVNVSYIN"
     gene            complement(5000..6043)
                     /locus_tag="RPH49_002335"
     CDS             complement(5000..6043)
                     /locus_tag="RPH49_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDY5125456.1"
                     /translation="MDILLGVGTLVLVLVIMTLFLKYAPYGKQGLQALSGAACATFLP
                     QAFLSYAIGGVFDIKFLQDIGDLAGSLSGIAVGILTCLNLGVAPVFAVIVGLVLHDFK
                     LLPAFIAAYGVAFLIKWIEKKVPEGLDLIVVILFAPAIAFGLASIITPGVLATLKQIG
                     SAVTAVGDNNPYALAVILGLVIPVTGMTPLSSMVLTSLLGLTGVPMAIGALTCTGSSF
                     VNLILFRKLNIGGPSKAFAVCIEPLTQIDLIAQYPVQLYGTNALIGVVNACIVTFSGL
                     VIGVKGMATPIAGAIVLFGFNNAVTSIVTIATVIIVSIVLAYIIGTLINKFNLMNINF
                     KMPSKKNHIKESV"
     gene            6592..6795
                     /locus_tag="RPH49_002336"
     CDS             6592..6795
                     /locus_tag="RPH49_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125457.1"
                     /translation="MQLSHSVKVAISIYLALIFITFTSYLVIILYTSMTGHDVSHFVL
                     DSQHSHHGSLTQKHLSLPEISFK"
     gene            6978..7913
                     /locus_tag="RPH49_002337"
     CDS             6978..7913
                     /locus_tag="RPH49_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HDY5125458.1"
                     /translation="MRYLANNHSALRLKGIILAIVGACLWGLGGTVSDFLFKYKNINV
                     DWYVTARLVVSGVFLLIMYKMMQPKRSIFSVFQDRRMLGKLLIFSILGMLVVQYAYMA
                     SINTGNAAIATLLQYIAPVYIIIWFVIRGVAKLTLFDVLAIIMTLLGTFLLLTNGSFS
                     NLVVNPASLFWGILAGVALAFYTIYPSDLLNRFGSILIVGWAMLISGVAMNLRHPIWH
                     IDITKWDISIILFLIFGIIGGTALAFYFFIDSLQYISAKETTLFGTVEPVVAVIASSL
                     WLHVAFKPFQIVGIILIMILILLLSLKRQPEALDE"
     gene            complement(7995..8963)
                     /locus_tag="RPH49_002338"
     CDS             complement(7995..8963)
                     /locus_tag="RPH49_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5125459.1"
                     /translation="MRKKWSTLAFGFLVAAYAHIRIKEKRSVKSYMLEQGIRLSRAKR
                     RFMYKEEAMKALEKMAPQTAGEYEGTNYQFKMPVTVDKHYGSTVYTVNDKQDKHQRVI
                     LYAHGGAWFQDPLKIHFEFIDELAETLNAKVIMPVYPKIPHQDYQATYVLFEKLYHDL
                     LNQVADSKQIVVMGDSAGGQIALSFAQLLKEKHIVQPGHIVLISPVLDATMQHPEIPD
                     YLKKDPMVGVDGSVFLAEQWAGDTPLDNYKVSPINGDLDGLGRITLTVGTKEVLYPDA
                     LNLSQLLSAKGIEHDFIPGYYQFHIYPVFPIPERRRFLYQVKNIIN"
     gene            complement(9084..9440)
                     /locus_tag="RPH49_002339"
     CDS             complement(9084..9440)
                     /locus_tag="RPH49_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDY5125460.1"
                     /translation="MVKQLNSVEAFREFIHQYPLAVVHVMRDQCSVCHAVLPQIEDLM
                     QSYPNVPLAVINQSQVEAIAGELNIFTVPVDLIFMNGKEMHRQGRFIDMQRFEHHLKQ
                     MNDSVNNDVDEHEYRK"
     gene            complement(9482..9892)
                     /locus_tag="RPH49_002340"
     CDS             complement(9482..9892)
                     /locus_tag="RPH49_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDY5125461.1"
                     /translation="MTTEGLLVAEKEIEVNGYDIDAMGVVSNIVYIRWFEDLRTAFIN
                     QHMNYSTMINQGISPILMKTEAEYKVPVTIHDKPVGRIYLVKASKMKWVFQFEIVSAH
                     GVHCIGTQTGGFYRLSDKKITSVPQVFQDILATK"
     gene            10428..10810
                     /locus_tag="RPH49_002341"
                     /pseudo
     CDS             10428..10810
                     /locus_tag="RPH49_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3385 a         1985 c         1604 g         3836 t
ORIGIN      
        1 aagaattttc aaaaatacaa ttaaatatcg gtgtaataaa tccctttata cataggagtt
       61 gtatacatga aactaaataa ctattcttta aaagttaaaa acaaacaact agttgacaat
      121 tgtgatttaa atttctatct tggtcagatc aatcacattg ttggtaaaaa tggtgtagga
      181 aaatctttat tagctaaaga tttcttacta aataatagtg gaaatatccc taagtccatt
      241 tctcaaaatg taaccttaat atcaagttca tcaaatattc ctaatgatat aacaaaagat
      301 tttttattat cattgttaaa atcaaaattt gaaaacaatc gacaaacatt cgataagatt
      361 tataacatac taaacatcga agcaataccg tctaacgtac tactaaaaaa cttgagtgat
      421 ggtcaaaaac aaaagcttaa attattaagt ttcttattgg aagatcatga tttaatcata
      481 ttagatgaag ttacaaacgc tttagacaag aaaacagtta atgaaattta tgaattttta
      541 aatgatttta ttcaaagcca tcaaactaaa actattatca atattacaca taatttatcc
      601 gatttaagtg ctttgccggg taaatacttt atttttaaag accttcaaat agaagagtac
      661 caatcaaaag aagaagtcat aaatgattac attaatttat aattgaggtg tccactttga
      721 aattagaatt taaaaaaagt atttccaata aaattattta cacgcttggt gtgctattca
      781 tattcctttt cttacttggg tattttttac caataggaat agacaaagtt aaaagtttaa
      841 gctatagcca gtttttcttc agttcatata ctgttgcaac gcaattaggg ttcttactat
      901 tttcatttgt tattgcatat tttattaata aagagtattc gaataaaaat atattatttt
      961 acaagctgat tggcgataat atctttacct tcttctataa aaaggtagca gtgttatttt
     1021 ttgaatgttt agtgttcata attctaagta tcactattat ttcaattata tattcggatt
     1081 tctcacatta cttactatta ataatcttat tttcactcgt tatcttacaa tatatcttag
     1141 ttgttggaac aattagtatg gtttcaccta acattttaat cagcttaggt atcagtattg
     1201 tatattggat tggttcagtc atcttagttg ccattaataa aaatatattt ggtatcgttg
     1261 ctccatttga ggcgagcaac acgatgtatc gtgccgtaga aaaaatattg aataacgagt
     1321 caacatttat atgtcctact gaaattataa atacagtatc attcttcgtt cttctattta
     1381 tagttaatac tattgtctta ttactaagta gaaagagatg gttgaaaatc ggtatgtagt
     1441 acataaaaag gagcggcatc cattgtcgct cctttttatt atgtattttt acaatctcca
     1501 ccaatgacac gtcgtcattg ttacctcaga ccaaacaaaa aaacagtctc gcaatcaaga
     1561 ctgttttcca ctcaatatat tcatccatta gcgtaatgga ttatttaact tctgtagcta
     1621 caaagatttt acgtgtttcc caaacgcctg tcttttcatt gtaatcatca caagtaatta
     1681 atgttaattg tttatcttta cctttttgtt catctagaac ttctacatct gtaggcttaa
     1741 catctcttat acttgtcatt ttatacttac gtgtttcatt accaacttta aagtacacca
     1801 tactaccttt tttggctgct ttaagatttg taaattgata gttcggacgg tcaatgaaag
     1861 tgtgccctgc aattgaaata ttttgatcat ctagtgattc gttttcttct gcaaagctta
     1921 cacctctatt taattgttca ggtgttgctg gtcctggata tactggttct ttaatatcag
     1981 catctggaat ttcaatatag cctgccactt tcgatttatc tttcggaatc tgaggtttag
     2041 cttgctgctt tttatcctta ctcgcctgtt cttttacatt tttatcatat tgttcaatct
     2101 tttcatcttt atctttatcg tgaagataat tatcgatatg tggtttagca aacaaatatg
     2161 ctgccactag gataagtacc acaccagcga ttgtcattaa tcgatttgtc cattttttca
     2221 tacgttaagg ctccttttat acatttcaca atgcctatta acatttcata tagtatacca
     2281 ttaatttcaa agtgactcat agcaattcat tttatactat aaaatttaca tgtatgcttt
     2341 tacgttagat ttcattacac atatttgcat tcaaataacg aaacgctttt aataattact
     2401 aagggggaat tgttatgatt agatgcgcta aaaaagagga tttaaacgct atattagtga
     2461 tatacaatga tgccattatc aatactacag ctgtttatac ttatgaacca caaaccatag
     2521 acgaacgtgt cgcatggttt gaaacgaaac aacgtaagca tgagcctatc tttgtatttg
     2581 aggaaaatgg aagtgtctta gggtttgcga cgttcggttc gtttagacct tggccagcat
     2641 acctatatac aatcgaacat tctatttatg tcgatgcttc agctagagga aaaggtattg
     2701 ctagtcaatt actacaccat ttaattgtgg aagcaaaagc taaaggttat cgtgcgctag
     2761 ttgcaggcat tgatgcttcc aacaaagcga gtattcagtt gcatcaaaag tttgctttta
     2821 agcatgccgg cacactgacc aatgtaggtt ttaaatttaa tcaatggtta gatttagcat
     2881 tttacgaatt agatttacaa gactagtaat gtttgaatca cataatataa acaagacgac
     2941 catgtcaatt cacttaacat aacaagccaa catataaaat tttaaacttc tcagggacaa
     3001 tttacatcgt cccttttatt ttttcttttc aaatactatc cccatagctt tgatttaacg
     3061 ctttttctca ataacaaaac gaatatagta gaacatgaaa acgataatca tgctgagcga
     3121 taaagattta aataatagat tgacccacgt tccctcagtc gtatatccat atgtaatcgt
     3181 tgtgttaatg atgaatgcta taaagatgat tgatagtctt agcatatcat cactcctttt
     3241 aagttatttt agatatacgg gggcgctttt gcaatcacta ttttgattag catgtatttc
     3301 ccataaattt ttcaacttct tcagagataa ttaagaagca tctatctggt actaatgatc
     3361 cagacagatg cttctttttt atcaatatct tattgttatc tcattaatta tttttaacca
     3421 tatcttcagc tgtgccaaag attttacgtt taattgcttc gccagttggt gtgcctgcta
     3481 gtccacccaa tccagtttca cgtaatgatg caggaaggtt acgaccaacc ttatccattg
     3541 cttcaataac ttcatcaaca ggtattctac tttcaatacc tgctaatgct aaatctgctg
     3601 aaattaaagc gttacccgaa ccaattgcat ttctcataac acaaggaatt tcaacaagtc
     3661 cggctactgg gtcacaaact aatcctaata aattgcttat cgctaatgcc atagcgtgcc
     3721 cggatgcttc tggtgatcct ccgaatatag ctactgctgc agctgccgcc attgcagatg
     3781 ctgaaccaac ttcagcttgg cagccacctg ttgcaccagc tacacttgca ttgtttgcta
     3841 cgacacgccc aaacaacgct gaagtgaata agaaatcaat catttgctct tctgttaaat
     3901 catgtgtttt ttctaattta aaaagtgcac cgggaatggt acccgaggaa ccagctgttg
     3961 gcgttgcaca aataataccc atcgcagcat tgacttcatt tgttgcaatg gcacctttga
     4021 ctgcgtcaat catttcatat ccagacaaag catgatgtgt ttcattataa tcacgtagtt
     4081 tagcagcgtc atgaccagtg tagcccgtta cactttcaac gccatcacct gtcgtccctt
     4141 tgattactgc gtctcgcatg acatctaaat tttgtttcat ttgcgctcgc acttcatcac
     4201 gtgatttacc gcttaattcc atttcttctt taaccatgat atccgcaaat gatatattat
     4261 tttctacggc ataatctata gtctctctaa ttgaatcaaa catgtttatt ccccctctaa
     4321 tttatatagg aaacgtttac gtcactgtat ttctctttaa ttgtatttaa tgtcgattct
     4381 gagattgctt tatttaatgg tattacaacc aagcatttat cttcatctat cttaataaat
     4441 tcatctttac agtctaattt catatcgttg atatcattaa tgaaatgatt tacttgtgct
     4501 ttagtcatat ttccgtcgac aactaaaatt ggtaatccat gatttaaatc tacttctagt
     4561 ccatttatat gaataccttt aattttaatt gtaccaccac cgattgaaat accgataatt
     4621 tcaatgtagc gaccatcatt acgagatgat ttaatataag cacagtttgg atgttgacca
     4681 atactatcgc cttcttcttc gatgatatct attttaatac catcatcagc tgcaatttct
     4741 aatgaagatt taattcggtt atcaaatgtt gaatatccca ttgctccacc cacaatagcg
     4801 acatctgtac catgtccttg gtgtgtttga gcaaatgatt cataataatg tatttcaata
     4861 tttttaggaa tatctcccaa tattgcgcgt gctgaattcc caatctttac tgcaccagcc
     4921 gtatgagaac ttgaagggcc catcataact ggtccgataa tatcgaaagc actttgataa
     4981 tcatagctct ttgccataat taaacactct ccttaatatg attctttttg ctcggcattt
     5041 taaagttgat attcattaaa ttaaacttat taattagtgt tccaataata taggctaaga
     5101 caatgctgac aataatcact gttgcgattg ttacaattga tgtcactgca ttattaaagc
     5161 caaacaatac gatggcgcct gcaattggtg ttgccatacc tttgacacct attactagtc
     5221 cgctaaatgt cacgatacat gcgttgacga ccccaatcag tgcatttgta ccatatagtt
     5281 gtactggata ttgcgctatt aaatcaattt gcgtcaatgg ctcaatacaa actgcaaatg
     5341 cttttgacgg tccaccaatg tttaattttc ggaataaaat aaggttaaca aatgagctac
     5401 ctgtacatgt tagtgctcca atagccatag gaacacctgt cagtcctaat aaacttgtta
     5461 ataccattga acttagcggt gtcatacctg taacaggaat cactagtcct aaaatgaccg
     5521 ctaatgcata tggattgtta tcacctaccg cagtgacagc actacctatt tgttttaatg
     5581 ttgctagcac accaggtgta ataattgatg caagtccgaa agcaattgct ggtgcaaata
     5641 agatcaccac aattaagtcc aagccttctg gaactttctt ttcaatccat ttaattaaaa
     5701 aagctacgcc ataagctgcg ataaatgctg gtaataattt aaagtcatgt aatactaaac
     5761 caacaatgac cgcaaatact ggtgcaacgc ctaagtttaa gcacgttaaa atacctactg
     5821 caataccgct taaacttcct gctaaatccc caatatcttg tagaaattta atatcaaata
     5881 cgccaccaat agcataactt aagaatgctt gtggtagaaa tgtcgcacaa gctgcaccgg
     5941 ataatgcttg tagtccttgt ttaccgtacg gtgcatactt taaaaatagc gtcatgatca
     6001 ctaaaaccaa gactaatgtg cctacaccta acagaatatc catttcccaa aaacctctct
     6061 ctatgtttat tttattttca gaccataaac atcgtacacc cttaagaaaa cgttttcaac
     6121 ttttatctgt tatcaaatca aatatttaag tgaaatattt catatttgtg aaagattttt
     6181 aaaatggatt gtttcaaaaa ctacttatgt tgtcattaat atttactaat taacttttca
     6241 ctctatattt caaacagttg tgtgaaagtt ttttgataac ttttttacat ctgaaagtga
     6301 gtaatatttc tgaaaatttt taatatttat acattttatc tttcgagcta tttatttttg
     6361 tttttgtgct gtgtttataa aaccgcacac tatattcaaa aataacttat tacacatata
     6421 tttgcaataa gataattaaa gtaggatatt atttttagtt ttctgatagg aatgattata
     6481 gtctataggt tgaatcttta ctttttttaa agctaaattt acatcaactt aacaatggct
     6541 gtttatactg aagatgaaaa tatttagtat aacttagtgg aggcgataaa gatgcaattg
     6601 agtcattccg ttaaagttgc aatttctatc tatttagcac ttatctttat aacgttcact
     6661 tcttatttag tcattatttt atatacgagt atgactggac atgatgtatc acatttcgtt
     6721 ttagatagtc agcattctca tcatggatct cttacgcaaa aacatttgag tcttcctgaa
     6781 atctcattta aatagtttat cctctgtgtt tcaacattca tttcccatat cgattcattt
     6841 atctatcatc tagaccacta catcttagat gattttttta ttttctcatt tcactctttc
     6901 ttaaaagtcg atataatgaa ttaaatcatt atcatacacc gacatatttt atgttgttgg
     6961 tgttaagttt taaaggggtg agatacttgg cgaacaatca ttcagctttg cgtttaaaag
     7021 gaattatact tgccattgtc ggtgcttgtt tatggggatt aggtggtact gtttctgatt
     7081 tcttgttcaa atataagaat attaatgtcg attggtacgt cactgctcga cttgtagtca
     7141 gtggtgtttt cttacttatt atgtacaaaa tgatgcaacc caaacgttca atatttagcg
     7201 tattccaaga tcgacgtatg ttaggcaaat tacttatctt cagtatactg ggcatgttag
     7261 ttgtacaata tgcttatatg gcatctatta atacaggtaa tgctgcgatt gcaacattac
     7321 tacaatacat tgcgccagtt tatattatta tttggtttgt cataagaggc gttgcaaaac
     7381 taacattatt tgatgtgctt gctattatca tgacactatt aggaacattt ttattattaa
     7441 cgaatggttc attttctaat ttagtcgtca atcctgcaag tttattctgg ggtattttag
     7501 ctggtgtagc actcgctttt tacacaattt atccttcaga cctacttaac cgcttcggtt
     7561 cgattctaat tgtcgggtgg gcaatgctta tttctggtgt tgcgatgaat ttacgccatc
     7621 caatttggca cattgatatc actaaatggg acatatcaat tatattattt ttaatctttg
     7681 gtattatcgg tggtaccgca ctcgcatttt atttctttat cgacagttta caatacatat
     7741 cagcgaaaga aacaacatta ttcggaactg ttgaacctgt cgtagccgtt atcgcaagca
     7801 gtctatggtt acatgtggca ttcaaaccat ttcaaatcgt aggcatcatt cttattatga
     7861 ttttaatttt attactatca cttaaaagac aacctgaagc attagatgaa taagaaaact
     7921 ctgataatca ctttagcaag taactattat ttaacaatgt agctaccttg taggtgatat
     7981 cagagttttt tattttaatt aataatattt ttcacttggt ataaaaagcg tcggcgctct
     8041 ggtatcggaa atactggata aatatggaat tggtaatatc caggtataaa gtcatgttcg
     8101 atacctttcg cactcaacaa ttgcgataag ttcaaagcat ctgggtacag tacttctttt
     8161 gtgccaacag ttaatgtaat acgacctaaa ccatctaagt caccattaat tggtgatact
     8221 ttgtagttat ctaaaggcgt gtcccctgcc cattgttcag ctaagaacac actgccatcc
     8281 acacctacca ttgggtcttt ctttaagtag tcaggaattt caggatgctg catcgttgca
     8341 tctaaaactg gtgaaattaa tacaatatgt cctggttgca caatatgttt ttcttttaac
     8401 aattgagcaa atgataaagc aatttgaccg cccgcagagt cacccattac aacgatttgt
     8461 ttagaatctg ctacttgatt caataaatca tggtacaact tttcaaaaag tacatacgtc
     8521 gcttgataat cttgatgcgg aatcttcgga tatactggca tgatgacttt agcattgagt
     8581 gtttctgcaa gttcatcaat aaattcgaaa tgaattttga gtgggtcttg gaaccatgcc
     8641 cctccatgtg catataatat aacgcgttga tgcttatctt gtttatcgtt aacggtataa
     8701 acggttgaac cgtagtgctt atccactgtt actggcatct taaactgata attggtgccc
     8761 tcatattcac ctgctgtctg tggcgccatt ttttctaatg ctttcatcgc ttcttcttta
     8821 tacataaaac gacgcttagc tctagataat cgtatacctt gttctaacat ataacttttc
     8881 acactgcgtt tttctttaat tctaatatgt gcgtatgctg ctactaaaaa tccaaacgca
     8941 agtgtagacc attttttacg catttgtcgt cactcctctt tgatgatttc tactatagta
     9001 ttaatgtacc atgctgattc ttattactac caatatttac tgggaaataa gttatgatgt
     9061 ctacataatc ttagcaatgc taatcatttg cgatattcat gctcatcgac atcgttattc
     9121 acactatcat tcatttgctt aagatgatgt tcaaaacgtt gcatatcgat aaaacgccct
     9181 tgacgatgca tttcttttcc attcataaaa attaaatcca caggtacagt gaaaatattt
     9241 aattctccag caatagcttc cacctgactt tgattaatca cagctaatgg cacattggga
     9301 tatgattgca tcaagtcttc aatttgtggt aaaacggcat gacacacgct acactgatcg
     9361 cgcatgacat gtacgactgc taacggatat tgatgaataa attcacggaa tgcttcgaca
     9421 ctatttaatt gcttaaccat ttcgaacacc ttcttacttt ttatatttta aaatgaagtc
     9481 attattttgt tgctaaaatg tcttgaaaca cttgtggcac agaggttatc ttcttatcgc
     9541 tcaatctgta aaaaccgcct gtctgtgtac caatacaatg cacgccatgt gcggacacaa
     9601 tttcaaactg aaacacccat ttcatcttgc ttgctttaac taagtaaata cgacctactg
     9661 gtttgtcatg tattgtgaca ggtactttat actctgcttc cgttttcata agtataggtg
     9721 aaatgccttg attgatcatt gttgagtaat tcatgtgctg attaataaat gctgttctca
     9781 aatcttcgaa ccatctaata taaacgatat tactaacgac acccatcgca tcaatgtcgt
     9841 aaccattcac ttcgatttct ttctctgcaa ctaatagacc ttctgttgtc ataatgacaa
     9901 atctccttat cttacaaata gatttaaaat catgttaatt tatttttatt actttcatga
     9961 taaaaataca agcaattgaa ctttattacg gaaaatcaaa cttttcaatg agactattaa
    10021 tttggctagt cgcgaagatg catttttcta aaatgtgaca aaaacataag caatgttttc
    10081 tatatctaac actaatattt aacttattat catcaacaca tctgctatac atcattgcgc
    10141 actaaaaaca ggctggaaca taaatcccta aaaaaacagc agtaagatat tttctaattg
    10201 aaaattatct tactgctgtt ctctatttat acaatacttc gtattgaatg gcttcgcttt
    10261 cctagggtgc cgtctcagcc tcggtcttcg actggcactg ctccctcagg agtctcgcca
    10321 ttagtactac gtattaacat gtaattttac tttgaaatac tttaaaaaaa taagacactt
    10381 tcgcataatt taataaatac cactaaacta aattaacgag gtgccttatg tataaaaatt
    10441 ataacatgac ccaacttaca ctaccaatag aaacttctgt tagaattcct caaaatgata
    10501 tttcgcgata tgttaatgaa atttttgaaa cgatacctga tagcgaattc gatgaattca
    10561 gacatcatcg tggcgcaaca tcctatcatc caaaaatgat attaaaaatc atcttatatg
    10621 catatactca atctgtattt tctggtcgta gaatagagaa attacttcat gacagtattc
    10681 gaatgatgta gttagctcaa gatcaaatac cttcttataa aactattaat cgttttagag
    10741 tgaatcctaa tactgatgcg ttaattgaat ctttatttat tcagttccat agtcaatgtt
    10801 taaagaaaaa
//
LOCUS       DAPSKH010000074        10581 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPSKH010000074 DAPSKH010000000
VERSION     DAPSKH010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10581
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.074"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..1108
                     /locus_tag="RPH49_002342"
     CDS             <1..1108
                     /locus_tag="RPH49_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDY5125462.1"
                     /translation="KKQVDFSDSYMMTKNIMLVKKDKVNEYKDIKDFNNKKVGAQKGT
                     EQEKIAQTEIENASITSLSRLPDVILALKSGKVEGAVVEKPVAEAYLKQNPKLGISNV
                     KFNEEEKDTVIAVPKDSPKLLSQINKTIKEVKDKGLIDKYMTNAANAMNDDSGFISKY
                     GSFFLKGIKITILISLIGVALGSILGAFVALMKLSKIKIISWIASIYIEILRGTPMLV
                     QVFIVFFGITAALGLDISALVCGTIALVINSSAYIAEIIRAGINAVDKGQMEAARSLG
                     LNYRQTMKSVIMPQAIKNILPALGNEFVTLIKESSIVSTIGVGEIMFNAQVVQGISFD
                     PFTPLLVAAALYFVLTFVLTRIMNMIEGRLNASD"
     gene            1101..1823
                     /locus_tag="RPH49_002343"
     CDS             1101..1823
                     /locus_tag="RPH49_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDY5125463.1"
                     /translation="MIKINNLNKVFGDNEVLKDINLEINQGEVVAIIGPSGSGKSTLL
                     RCMNLLEVPTKGQVIFEGNDLTEKGTQVDKLRQKMGMVFQNFNLFPHKKVVDNIILAP
                     KLLKKDNNDELHKEALSLLDKVGLKEKADVYPNQLSGGQKQRVAIARALAMHPDVILF
                     DEPTSALDPEVVGDVLKVMKDLAKEGMTMVVVTHEMGFAKDVSDKVIFMADGVVVESG
                     TPVEIFEQPQHERTQNFLARVL"
     gene            1973..3100
                     /gene="queG"
                     /locus_tag="RPH49_002344"
     CDS             1973..3100
                     /gene="queG"
                     /locus_tag="RPH49_002344"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDY5125464.1"
                     /translation="MDTKQLKQDIIDYAYTIGIDSIGFTTADPFDELKQKLEAYHANG
                     YASGFEESDIALRTEPKLSLPTARSIIAIAVGYPNKLKGAPKSVRGDRRGLFARASWG
                     QDYHTIMRKRLDMLAAFIESKVPDVEIKSMVDTGVLSDRAVAERAGLGFVGRNGFVIN
                     PKLGTWTYLGEMLVSIPFEPDDPLLDSCGDCTICVDRCPTSALVGNGQLNSQKCISFL
                     TQTKGYMPDQYRYKIGNRLYGCDTCQQVCPKNRGINTEQDDIILEPEILKPRLVPLLR
                     MSNKEFKQTYGHLAGAWRGKKPIQRNAILALAHFNEVDAIPELKKVATTDERPMIRAT
                     AYWAIGQILGEEARDFINANYDQEDAEVQNEMIKGLDTRRE"
     gene            3105..3575
                     /gene="trmL"
                     /locus_tag="RPH49_002345"
     CDS             3105..3575
                     /gene="trmL"
                     /locus_tag="RPH49_002345"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDY5125465.1"
                     /translation="MTNHIVLYQPEIPANTGNIARTCAGTNTHLHLIKPLGFRTDDKM
                     LKRAGLDYWEFVNITYHDSIEAFFEATNGEYYLLTKFGKKTYSDFDFSNHDKDFYFIF
                     GKETTGLPDWVKEKYQDTALRIPMSEHIRSLNLSNTAALLIYEALRQQDFPGLN"
     gene            3734..4333
                     /locus_tag="RPH49_002346"
     CDS             3734..4333
                     /locus_tag="RPH49_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate isomerase"
                     /protein_id="HDY5125466.1"
                     /translation="MAMNFKVFDNSQLVAEYAADIIRKQFNNNPTTIAGFHLDTDQAP
                     VLDELKKNVEKHAVDFSQINILDYDDKKSYFEALGVPAGQVYPIAYEKDAIELIADKI
                     KTKENKGKLTLQVVSIDEQGKLNVSIRQGLMEAREIFLVVTGANKRDVVEKLYQENGK
                     TSFEPADLKAHRMVNVILDKEAAAGLPEDVKAYFTSRFA"
     gene            4358..4510
                     /locus_tag="RPH49_002347"
     CDS             4358..4510
                     /locus_tag="RPH49_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125467.1"
                     /translation="MSKDKDPKLNYHEEENSMVTDFEDLKELSKEMEQISDQNDQEKN
                     SEEDSQ"
     gene            5345..5740
                     /locus_tag="RPH49_002348"
     CDS             5345..5740
                     /locus_tag="RPH49_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125468.1"
                     /translation="MLGKYWIQLLIATVIISLISIKAFPLAIGALYLPVIFKVIKLQL
                     NLSKGLIDDVNAQTFIKSNQSGIVISVICCLLITGILYYTLDGFYASLTGVLGTLVAL
                     NPYTTIVSAVLYILTAIATVEATKTKYRN"
     gene            5936..7321
                     /gene="fumC"
                     /locus_tag="RPH49_002349"
     CDS             5936..7321
                     /gene="fumC"
                     /locus_tag="RPH49_002349"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDY5125469.1"
                     /translation="MSVRIEHDTFGEIEVPADKYWGAQTERSKRNFPVGKERMPIEVV
                     YGFAQLKRAAALANFDLGKLSEAKKDAIVYACDQILSGELDEHFPLVVWQTGSGTQSN
                     MNVNEVVSYVANMYLKDHQSDESIHPNDDVNKSQSSNDTFPTAMHVALYQEVETKLEP
                     ALKLLRNTLKEKEDKFDSIIKIGRTHLQDATPIKLGQEISGWRYMLDRCEIMLSESKK
                     HILNLAIGGTAVGTGINAHPEFGDKVAQYISENTGYPFVSSENKFHALTAHDEVVQLH
                     GTLKALAGDLMKIANDVRWLASGPRAGLAEISIPENEPGSSIMPGKVNPTQCEMLTMV
                     AVQVMGNDTVVGFASSQGNFELNVYKPVIMHNTLQSIYLLADGMETFNNNCAVGIEPI
                     EENIDNYLNQSLMLVTALNPHIGYEKAAQIAKKAHKEGLTLKESAIQTGYVTEEQFEA
                     WIKPEDMVDPH"
     gene            complement(7784..8605)
                     /locus_tag="RPH49_002350"
     CDS             complement(7784..8605)
                     /locus_tag="RPH49_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDY5125470.1"
                     /translation="MKFKIPENFNDLSLRDIFQQLKVPKKDLHHLNMSKDITINDKPA
                     RLMDKVHTGDDVFVPTTDEKSNYVPSYRYAQIKYEDDDMAIVMKPKGVKTHPNDLKES
                     NTLMNHVIYTVDSDYVEPIHRLDQETVGLLIVAKNPLMKKILDRMLEDNDITRIYKAN
                     VKALLPLKPQTIDMPIGKDKFHSNKRRVSPTGQRAITHILTSKMIKETVCQLEIKLDT
                     GRTHQIRVHLAEIGHPVIGDPLYGDSTLRQLELESYKIEFVHPLTKEVISVSLDD"
     gene            8768..9880
                     /locus_tag="RPH49_002351"
     CDS             8768..9880
                     /locus_tag="RPH49_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing sensor histidine kinase"
                     /protein_id="HDY5125471.1"
                     /translation="MEQRTRLALLKEIAEFLNEETEMYSMTQGALKYLIEGSNFTTGW
                     IFFINSVGEHELVSHVALPQSLTADHCHYIKDGSCWCVKAFNQGRLMKASNIVNCSRI
                     NLASKAFPSQNDNITHHATVPLKSGQEQFGILNVASPNTEIYSDEDLELLESVAFQLG
                     SAIKRIYLTDREKEAAKINERNRLARDLHDSVNQMLFSVKLTAHAAYGVSNESIAKQA
                     FKTIEETSQNAVNEMRALIWQLKPVGLEQGLIHALTAYSKLMHIQLNVNVEGLIDLSN
                     EIEENIYRALQECINNVKKHADTNKMDLTLKQMNDILYIDVIDYGQGFEIDNVQIASS
                     HGINNIKQRVKLLRGKVTFHSQPTKGTQIQFTIPIK"
     gene            9902..10525
                     /locus_tag="RPH49_002352"
     CDS             9902..10525
                     /locus_tag="RPH49_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5125472.1"
                     /translation="MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGETFLEYLK
                     EHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVLVLTSYVDDEHVISAINKGADGY
                     EMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
                     GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI"
BASE COUNT         3823 a         1507 c         1945 g         3306 t
ORIGIN      
        1 taagaagcaa gttgattttt cagattcata tatgatgact aaaaatatca tgcttgtaaa
       61 gaaagataaa gttaatgaat ataaagatat caaagacttt aataataaaa aagtaggggc
      121 acaaaaggga actgaacaag aaaaaatcgc tcaaaccgaa attgaaaatg catctattac
      181 ttcattaagc cgtttaccag acgttatatt agctctgaaa agtggaaagg ttgaaggtgc
      241 tgtagttgaa aaacctgtag cagaagcata tttaaaacaa aatcctaaat taggaatttc
      301 caatgtgaaa tttaatgaag aagaaaaaga tacagtgata gcagtgccaa aagattcacc
      361 aaaattattg tcacaaatta ataaaacgat taaagaggtt aaagataaag gattaatcga
      421 taaatatatg actaatgctg caaatgcgat gaatgatgac agtggtttta tttctaagta
      481 tggtagtttt ttcttgaaag gaattaagat tacaatatta atttcactta tcggtgttgc
      541 attaggttct attttaggtg cattcgttgc gttaatgaaa ttaagtaaaa taaaaattat
      601 ttcatggatt gcttctatct atatcgaaat attaagagga acaccaatgt tagttcaagt
      661 atttatcgta ttctttggta taactgctgc attaggacta gacatttcag ctcttgtttg
      721 tggaacaatt gcattagtta ttaattcttc agcttacatt gctgaaatta ttcgtgcagg
      781 tataaatgct gttgataaag gccaaatgga agccgcacgt agtctaggtt tgaattatag
      841 acaaacgatg aaaagtgtaa ttatgccaca agcaattaaa aatattttac cagctttagg
      901 taatgaattt gtcactttaa ttaaagaatc atctattgtg tcaacaattg gagttggcga
      961 aattatgttt aatgcacaag tggttcaagg tatttcattt gacccattca caccattact
     1021 agtggcagca gcattatact ttgtcttaac atttgtactt acacgcatta tgaacatgat
     1081 tgaagggaga ttgaatgcca gtgattaaaa taaacaatct taataaagtt tttggagata
     1141 atgaagtttt aaaagatatc aatcttgaaa tcaatcaagg ggaagtagta gcaataatag
     1201 gtccatctgg tagtggtaaa agtacattgt taagatgtat gaatttatta gaagtaccca
     1261 ctaaaggtca agtgattttt gaaggcaatg acttaacgga aaaagggaca caagtagata
     1321 aactacgaca aaaaatgggt atggtatttc aaaacttcaa cctatttcca cataaaaaag
     1381 ttgtcgataa tattatttta gctcctaaat tattaaagaa agataataac gatgaattgc
     1441 ataaggaagc attgtcgtta ttagataaag tgggattaaa agaaaaagca gatgtatatc
     1501 cgaatcaatt atcaggtggt caaaaacaaa gggtagcaat tgcaagagct ttagcaatgc
     1561 atccagatgt tattttattc gatgaaccaa cttcagcatt agatcctgag gtggttggtg
     1621 atgtattaaa agtaatgaaa gacctagcca aagaaggtat gaccatggtg gttgtgacac
     1681 atgaaatggg atttgccaaa gatgtaagtg acaaagttat atttatggca gatggcgttg
     1741 tcgtagagtc aggcacacca gtcgaaatat ttgaacaacc gcaacatgaa agaacacaaa
     1801 atttcttagc aagagtatta taacaaccta acgaagcttg aatatatgat gcgcaccaca
     1861 aagttatatc atatattcaa gctttttatt attaaaatca tggaaatgaa acctcaatat
     1921 gaataatggt tgtgttaaaa taacatagta ttattttatg gggggcatac gattggatac
     1981 aaagcagtta aagcaagata tcattgacta tgcatataca attggtatcg acagtattgg
     2041 atttactact gccgatccct ttgatgaatt gaagcaaaag ctagaagcat atcatgcaaa
     2101 tggttatgcc tcaggatttg aagaatctga tattgcttta cgaacggagc ctaaattatc
     2161 tttaccaaca gcaaggtcaa tcatagcaat tgcagttggt tatcctaaca aactgaaagg
     2221 tgcacctaag agtgttagag gtgatcgcag aggcttattt gctagagcat cgtggggtca
     2281 agattatcat acaattatgc gtaaacgatt agacatgtta gctgcattta ttgaatctaa
     2341 agttccagat gttgaaatca aatctatggt agatacgggt gtattatcag atagggcagt
     2401 agcagaacgt gcaggtttag gatttgttgg tcgtaatggc tttgtcatca atcctaaact
     2461 aggaacatgg acatacctcg gtgaaatgtt agtcagtata ccttttgaac ctgatgatcc
     2521 attattagat agctgtggtg attgtacaat ttgtgttgat cgttgtccaa caagtgcatt
     2581 agttggaaat ggccaattaa atagtcagaa atgcattagt tttttaacac aaacaaaagg
     2641 ctatatgcct gaccaatatc gttataaaat tgggaataga ttatatggtt gcgatacgtg
     2701 tcaacaagtt tgcccgaaaa atagaggtat taataccgaa caagatgaca tcattttgga
     2761 accagaaatt ttaaagccaa gattggtacc tttactacgt atgtctaata aagaattcaa
     2821 acaaacatat ggtcaccttg caggtgcttg gcgtggtaaa aagccgatac aacgaaatgc
     2881 tattttagca ttagcgcatt ttaatgaagt ggatgcaatt ccagaattga aaaaagttgc
     2941 aacaacagat gaaagaccga tgattcgagc aactgcttat tgggccattg gtcaaattct
     3001 tggggaagaa gcaagagatt ttatcaatgc taattatgat caagaggatg cagaagttca
     3061 gaatgaaatg ataaaaggat tagacacaag gagagaatag taatatgaca aatcatatcg
     3121 ttttatatca accagaaatc ccagctaata ctggtaacat tgcacgtacg tgtgcaggta
     3181 caaacacaca tttacattta attaaacctc ttggatttag aactgatgat aaaatgttaa
     3241 aaagagccgg tttagattat tgggaatttg tgaatattac gtatcatgat agtattgaag
     3301 cattttttga agccacaaat ggcgagtatt acttattaac aaaatttggt aaaaagactt
     3361 atagtgattt tgatttttca aatcatgaca aagattttta cttcattttt ggaaaagaga
     3421 cgacaggatt accagactgg gtgaaagaga aatatcaaga cacagcatta agaattccta
     3481 tgagtgaaca tattcgttca ttaaatttat caaatactgc tgcgttgtta atttatgaag
     3541 cgttacgtca acaagatttt ccgggattga attaaaattt actcattttc attataaaaa
     3601 tgatgcttaa gtgctatatt tagagtataa gcatgttaaa gttaaatggt ttgatatatt
     3661 gaaagttagg gtataataat tattaatatc gccgttttta tgtaaaatgc aaactaagag
     3721 gagtgtagaa atcatggcaa tgaactttaa agtctttgac aatagtcaac ttgtagcaga
     3781 atatgctgct gatattatta gaaagcaatt taacaataat cctactacaa ttgcaggttt
     3841 tcatttagat acagatcaag cgccagttct agatgaatta aagaaaaatg ttgaaaaaca
     3901 tgctgttgat tttagccaaa taaatatttt agattatgac gataaaaaat catatttcga
     3961 agcgttaggt gtaccagcag gtcaagttta tccaattgct tatgaaaaag atgcaatcga
     4021 attaatcgct gataagatta aaactaaaga aaataaaggg aaattaacat tacaagttgt
     4081 ttctatcgat gagcaaggta agttaaatgt tagtattcgt caaggactaa tggaagcaag
     4141 agaaattttc ttagtagtga caggtgctaa taaacgagat gtagttgaaa aattatatca
     4201 agaaaatggt aaaacaagct tcgaaccagc cgatttaaaa gcacatagaa tggtaaatgt
     4261 tattcttgat aaagaagcgg ctgcaggttt acctgaagat gttaaagctt actttacgtc
     4321 acgctttgct taattaaaaa tctgtgaggt attgattatg tctaaagaca aagatccaaa
     4381 attaaattat catgaagaag aaaacagtat ggtaactgat tttgaagatt taaaagaatt
     4441 aagtaaagaa atggaacaaa tttccgatca aaatgatcaa gaaaaaaatt ctgaagaaga
     4501 cagtcagtaa agtattataa ttgtgtaata ttcagctatt tatcatgtaa acaatgtata
     4561 gtatagaaca tatatcaaat aggattgatt atcttgaata tgaagttagg tagcattttg
     4621 ttacctagct tttttataat attcatagaa gctgactttc cgccagcttc tgtgttgggg
     4681 caccgccaac tcgcacgtta ttgtaaggtg actttccgcc agcttctgtg tttttggccc
     4741 gtttccccaa cttgcattgt ttgtagaaat tgaggattca atttcactat gttggggccc
     4801 cgccaacttg cattgtctgt ataaattgga aatccgattt cgctatgttg tggccccgcc
     4861 aacttgcatg ttattgtaag ctgactttcc accagttcct gtgttgtggc cgtttcccca
     4921 acttgcatca tctgtagaaa tagagaatcc aatttcaatg tgtttgtggc ccgtttcccc
     4981 aacttgcatc atctgtagaa attagaaatc cgatttcact atgttgggcc tcgccaactt
     5041 gcatgaaata gtaagctgac tttccgccag cttctatgtt tgtggcccgc agtcaactac
     5101 tgccaatata actttgtaga gaatagaaca ttgatttgtg caccagacat agtaatatat
     5161 caaaagttca attttaaata ttaaaacacc atttaaacgg aattgataat taattactcc
     5221 agacataatt gaaagaagtc atctatcagt aatattttta acgaaatcat taaaccgcgt
     5281 ttcttaatat gccaagatta tgatatgcta ttgaagaatg aaattagagg agatttatat
     5341 atttatgtta ggaaaatact ggattcaatt attgatagca acagttatta taagtttaat
     5401 atcaattaaa gcttttccat tggcaattgg ggcattatat ttacctgtta ttttcaaagt
     5461 aataaaatta caactcaatt tatcaaaagg attaatcgat gatgttaatg cgcaaacatt
     5521 cattaaaagt aatcaatcag gtattgtaat aagtgttatt tgttgtttat taataacagg
     5581 aatattgtat tatacacttg atgggtttta tgcgagttta acaggagttt taggtacgct
     5641 tgttgcttta aatccatata cgacaattgt tagtgctgta ttatatatac ttacagctat
     5701 tgctacggtt gaagctacta aaacaaagta tcgtaattaa acttagttca acaataacta
     5761 aataatgata gataacacac taatcgtatg accgtatcac tgtaataaag ggtgagtacg
     5821 tgcgattagt gtatttttat ttcaaattat gaaaacgttt taatcataaa ttgctcaatt
     5881 aaattattta atgatatact acagttaaat aaacagtgat aaggggagaa attgaatgtc
     5941 agtaagaatt gaacatgata cttttggaga aatagaagta cctgcagata aatattgggg
     6001 tgctcaaaca gaaagaagta aacgcaattt cccagttggt aaagagcgta tgccaatcga
     6061 agtagtttat ggttttgcac aactaaagcg tgcagcagca ttagctaatt ttgatttagg
     6121 aaaattaagc gaggcaaaga aagatgccat tgtatacgca tgtgatcaaa ttttatcagg
     6181 tgaattagat gaacacttcc cactagttgt atggcaaaca ggaagcggta cacaaagtaa
     6241 tatgaatgtg aacgaagtag taagttatgt tgctaatatg tatttaaaag atcatcaaag
     6301 tgatgaaagt atccacccaa atgatgatgt aaataaatca caaagttcga atgatacatt
     6361 cccaactgct atgcacgttg cattatatca agaggttgaa acaaaattag aacctgcatt
     6421 aaaactttta agaaatactt tgaaagaaaa agaagacaaa tttgattcaa ttattaaaat
     6481 tggtcgtaca catttacaag atgcaacgcc gatcaaacta ggacaagaga ttagtggctg
     6541 gcgttatatg cttgaccgtt gcgaaataat gttatctgaa tctaagaagc acattttaaa
     6601 tctagccatt ggtggtacgg ctgttggtac tggtattaat gcgcatcctg aatttggtga
     6661 taaagtggca cagtatattt ctgaaaatac gggttatcca tttgtatctt ctgaaaataa
     6721 attccatgca ttaacagcac atgatgaagt agtacaacta catggaacat tgaaggcgct
     6781 agcaggagac ttaatgaaaa ttgctaatga tgtgagatgg ttggcttcag ggccacgagc
     6841 tggtttggca gaaatttcta tccctgaaaa tgaaccaggt tcatcaatta tgcctggtaa
     6901 agttaatcct acacaatgtg aaatgttaac aatggttgca gtccaagtaa tgggtaatga
     6961 tacagttgtt ggcttcgcaa gttcacaagg taactttgaa ttgaatgttt ataaaccagt
     7021 tattatgcat aatacactac aatcaattta ccttttagct gatggtatgg aaacatttaa
     7081 taacaattgt gcagtgggca ttgaaccaat cgaagagaat attgataatt atttaaatca
     7141 atcattaatg ttagttactg cattaaatcc acatattggt tatgaaaaag ctgctcaaat
     7201 tgctaagaaa gcccataaag aaggtttaac tttaaaagaa tctgcaattc aaactggata
     7261 tgttacagaa gaacaatttg aagcatggat taaaccagaa gatatggtag atcctcatta
     7321 attaaatatt aatataaaat aaagtttggg cattacaggt agatgtagtg ttcaagcttt
     7381 attttttgtc tatgtcaaat tgaacttata agtctgattt gatatagagc catgaaaagg
     7441 aaaaactttt catggagtcc gttttattat agaacctatt ttttatatga tgaattgttg
     7501 tacatgtatt ggccaaacaa cctgtgataa aaatcttatg atgtcatgta ttgtccatag
     7561 atacacgtaa cgcagttgaa aaagactaca agtcattatc caaggatgtt ataaaatgaa
     7621 taattactaa aatatcaaaa tataaaatct taagcatcgt aaaaaacaaa aaaaccgaac
     7681 atctgaaaaa attaataatt ttccatctat ccgatttaag ttgatacttg atttagttac
     7741 aatgcggtat tgcatgttta aatatcatgc aaaactaatc aaattagtca tccaaagaaa
     7801 cggaaatgac ttccttagtt aagggatgca caaactctat tttgtaactt tcaagttcta
     7861 attgtcttaa cgttgaatca ccgtataaag gatcaccaat aactgggtga ccaatttcag
     7921 ctaaatgcac acgaatttga tgagtacgtc cagtatccaa cttgatttca agttggcaca
     7981 cagtttcttt tatcattttt gaagttaaaa tgtgtgtaat tgcacgctgt ccagtaggag
     8041 acacacgtcg tttattcgaa tggaatttat ctttaccaat tggcatatca atcgtttgtg
     8101 gttttaaagg taaaagtgct ttaacatttg ctttgtatat ccgcgtaata tcattgtctt
     8161 ctaacatgcg atcaagaatt tttttcatta aaggattttt agcaacaatt aataatccta
     8221 ctgtttcctg gtccagtcga tgaattggtt cgacataatc gctatcaacc gtgtaaatca
     8281 catgattcat taaagtattg ctttctttta aatcattagg gtgggtctta acacctttag
     8341 gtttcattac gattgccata tcatcgtctt cgtatttaat ttgtgcataa cgataacttg
     8401 gaacataatt acttttttca tcggtggttg ggacaaatac atcgtcgcca gtatgcactt
     8461 tatccattaa tcgcgcaggt ttatcattaa tagtaatatc tttagacata tttaaatgat
     8521 gtaaatcttt tttaggtacc ttaagttgtt ggaaaatatc tcgtaaactt aagtcattaa
     8581 agttttctgg tattttaaat ttcataaaat cctcctatag tctttaatat catatcacaa
     8641 atcagttctc cgaaatataa ctattaagta atcaaggcca ttttatcatg ttcacgtcta
     8701 agatttaaaa atataataac tcaatgtata atagttaata cacgtaaaaa tgaattggag
     8761 cgatttgatg gaacaaagga cgcgactagc tttattaaaa gagattgccg aatttttaaa
     8821 cgaagaaact gaaatgtata gcatgaccca aggtgcgtta aaatatttaa ttgagggcag
     8881 taatttcacg acaggctgga tatttttcat caatagcgta ggtgaacatg aacttgtatc
     8941 acatgtggct ttaccacaat ctttgacagc agaccactgt cactatatta aagatgggtc
     9001 ttgttggtgt gtgaaagcat ttaatcaagg taggctaatg aaagcgtcga atatcgtcaa
     9061 ttgttctcgt attaacttag cctctaaagc atttcctagc caaaatgaca atattacaca
     9121 tcatgcaacg gtaccactta aatcgggtca agaacaattc ggcattttaa atgtagcgtc
     9181 accaaatact gaaatatata gtgatgaaga tttagagttg ctagagtctg tcgcatttca
     9241 attagggtca gccatcaaac gtatttattt aacagaccgt gaaaaagaag cagcaaaaat
     9301 taatgaacgt aatcgtttag ctagagattt acatgattca gtaaatcaaa tgttattttc
     9361 tgtaaaacta acagcacatg ctgcgtatgg cgtgtcaaac gaatccatcg ctaaacaagc
     9421 attcaagacg attgaggaaa cgagtcaaaa tgccgttaat gaaatgcgtg cattgatttg
     9481 gcaacttaag ccagttggac ttgagcaagg tttaattcat gctttgacag catatagtaa
     9541 attaatgcat atacaattaa atgtaaatgt agaaggttta atcgatttat ctaatgaaat
     9601 cgaagaaaac atatacagag cattacaaga gtgtattaat aatgttaaga aacatgctga
     9661 tacgaataaa atggatctta cattaaaaca aatgaacgat atactatata ttgacgtgat
     9721 tgattatggt caaggatttg agatcgataa tgttcagata gcttcatcac acggtataaa
     9781 taacataaaa caaagagtta aattattaag aggtaaagtg acctttcatt ctcagccaac
     9841 aaagggtaca caaatacaat tcacaattcc tataaaatag cttgatttaa ggagataacc
     9901 catgaacaaa gtaatattag tagatgacca ttatattgtg cgacaaggat tgcgattttt
     9961 attatccacg attgaaaaca tagaagtttt acaagacttt gcagatggag aaacattttt
    10021 agaatattta aaagagcatg agcaccctga tattgtgcta ttagatttag tgatgcctgg
    10081 catgaatggt attgaaatta cggaatatat taaggcacat tatccggata taaaagtttt
    10141 ggtattaaca agttatgttg atgatgaaca tgtaatttca gcaatcaata aaggtgctga
    10201 tggttatgaa atgaaagacg ttgagcctca gcaattaatt gaaactatta gacgagttat
    10261 gaacggtgaa aaaatgatac atcctaaggc acaagatgta ttcgaaacag ttagccaaaa
    10321 accacactac acgaataagt tgtcaaagag agaaattgaa gtgttacgtg aaatggttaa
    10381 aggtaaaaca aataaagaga ttgcagaaac tttatttgta tctgaaaaaa caattaaaac
    10441 acatgtcagt catatattta gtaaattaca agttagcgat cgtacacaag cagcaattta
    10501 tgcaatggaa aataagttga tttagaatga gcttttaaat atttgtcgaa aattagacaa
    10561 tttttaatct gattttgatg a
//
LOCUS       DAPSKH010000075        10229 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPSKH010000075 DAPSKH010000000
VERSION     DAPSKH010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 10229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10229
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.075"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            138..407
                     /gene="rpsN"
                     /locus_tag="RPH49_002353"
     CDS             138..407
                     /gene="rpsN"
                     /locus_tag="RPH49_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009384394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDY5125473.1"
                     /translation="MAKKSKIAKERKREELVNKYYELRKELKAKGDYEALRKLPRDSS
                     PTRLTRRCKVTGRPRGVLRKFEMSRIAFREHAHKGQIPGVKKSSW"
     gene            564..1541
                     /gene="guaC"
                     /locus_tag="RPH49_002354"
     CDS             564..1541
                     /gene="guaC"
                     /locus_tag="RPH49_002354"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDY5125474.1"
                     /translation="MKIFDYEDIQLIPNKCIVESRSECDTTIQFGPKKFKLPVVPANM
                     QTVMNEKLAKWFAENDYFYIMHRFDEEARIPFIKHMQNSGLFASISVGVKKAEFDFIE
                     KLAQEKLIPEYITIDIAHGHSDSVINMIKHIKNHIPDSFVIAGNVGTPKGVRELENAG
                     ADATKVGIGPGRVCITKIKTGFGTGGWQLAALNICSKAARKPLIADGGIRTHGDIAKS
                     IRFGASMVMIGSLFAAHEESPGETVELDGKQYKEYFGSASEFQKGEHKNVEGKKMFVE
                     HKGSLMDTLKEMQQDLQSSISYAGGKDLKSLRTVDYVIVRNSIFNGDRD"
     gene            1563..2579
                     /locus_tag="RPH49_002355"
     CDS             1563..2579
                     /locus_tag="RPH49_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001789887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CAP domain-containing protein"
                     /protein_id="HDY5125475.1"
                     /translation="MKKFIVTVVAFLSIIIIAPITEFKPFIHLQNEVRQYIDIHINKE
                     TISAENKLDTPKKQQFAFNNIQMNMSKSDVEKTLNKPKRVTFNEYGTKWYTYYDDDYN
                     NFIMVSYIKDKVNALYTNQNIITSKSKIKYNTPKSVVIQRLGEPETEIVKGRVRYEQN
                     NKEYDVFHKNHIYTTVFYDKHRRNNVTAVLQVSDAMENRLKEQYGAPSKSLADSFELQ
                     NFDLVNAERKQHQLSTLKYSKQNSETARKHSKDMANNHYFDHTNLKGQSPFDRLKKDG
                     ITFNSAGENLAYGQVSSIYAHQGLMNSIGHRKNILNDTFKILGVGVDFNDEKQPFWTE
                     NYTG"
     gene            complement(2958..3581)
                     /gene="lexA"
                     /locus_tag="RPH49_002356"
     CDS             complement(2958..3581)
                     /gene="lexA"
                     /locus_tag="RPH49_002356"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDY5125476.1"
                     /translation="MRELTKRQSEIYNYIKQVVQMKGYPPSVREIGEAVGLASSSTVH
                     GHLSRLEEKGYIRRDPTKPRAIEIVSDQTSDNINMEETIHVPVIGKVTAGVPITAVEN
                     IEEYFPLPEHLTSTHNSDIFILNVVGDSMIEAGILDGDKVIVRSQTIAENGDIIVAMT
                     EEDEATVKRFYKEKNRYRLQPENSTMEPIYLDNVAVIGKVIGLYREM"
     gene            3724..3957
                     /locus_tag="RPH49_002357"
     CDS             3724..3957
                     /locus_tag="RPH49_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125477.1"
                     /translation="MFYNKYKNVSTYIIIFLVSSAAFAIFLLSANISAHSEQVYEMTD
                     HQIKNNTINKAYEHKDPTNNSEQRDGKVFALIN"
     gene            4093..4332
                     /locus_tag="RPH49_002358"
     CDS             4093..4332
                     /locus_tag="RPH49_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 domain-containing protein"
                     /protein_id="HDY5125478.1"
                     /translation="MSNSDLNIERINELAKKKKEVGLTQEEAKEQTALRKAYLESFRK
                     GFKQQIENTKVIDPEGNDVTPEKIKEIQQKRDNKN"
     gene            4453..6441
                     /gene="tkt"
                     /locus_tag="RPH49_002359"
     CDS             4453..6441
                     /gene="tkt"
                     /locus_tag="RPH49_002359"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001661967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDY5125479.1"
                     /translation="MFNEKDQLAVDTLRALSIDTIEKANSGHPGLPMGAAPMAYTLWT
                     RHLNFNPQSKDYFNRDRFVLSAGHGSALLYSLLHVSGSLELEELKQFRQWGSKTPGHP
                     EYRHTDGVEVTTGPLGQGFAMSVGLALAEDHLAGKFNKEGYNVVDHYTYVLASDGDLM
                     EGISHEAASFAGHNKLSKLVVLYDSNDISLDGELNKAFSENTKARFEAYGWNYLLVKD
                     GNDLEEIDKAITTAKSQEGPTIIEVKTTIGFGSPNKAGTNGVHGAPLGEVERKLTFEN
                     YGLDPEKRFNVSEEVYEIFQNTMLKRANEDESQWNSLLEKYAETYPELAEEFKLAISG
                     KLPKNYKDELPRFELGHNGASRADSGTVIQAISKTVPSFFGGSADLAGSNKSNVNDAT
                     DYSSETPEGKNVWFGVREFAMGAAVNGMAAHGGLHPYGATFFVFSDYLKPALRLSSIM
                     GLNATFIFTHDSIAVGEDGPTHEPIEQLAGLRAIPNMNVIRPADGNETRVAWEVALES
                     ESTPTSLVLTRQNLPVLDVPEDVVEEGVRKGAYTVYGSEETPEFLLLASGSEVSLAVE
                     AAKDLEKQGKSVRVVSMPNWNAFEQQSEEYKESVIPSSVTKRVAIEMASPLGWHKYVG
                     TAGKVIAIDGFGASAPGDLVVEKYGYTKENILNQVMSL"
     gene            6719..6961
                     /locus_tag="RPH49_002360"
     CDS             6719..6961
                     /locus_tag="RPH49_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011275855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDY5125480.1"
                     /translation="MATWLAIIFIVAALILGLIGGFLLARKYMMDYLKKNPPINEEML
                     RMMMMQMGQKPSQKKINQMMTMMNKNMDQNMKSAKK"
     gene            6948..7046
                     /locus_tag="RPH49_002361"
     CDS             6948..7046
                     /locus_tag="RPH49_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125481.1"
                     /translation="MRKSKFAIDRGYFPDMEMASFYNQINKNKYVY"
     gene            7140..7607
                     /locus_tag="RPH49_002362"
     CDS             7140..7607
                     /locus_tag="RPH49_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CcdC family protein"
                     /protein_id="HDY5125482.1"
                     /translation="MLYLIFSIIVALFMGTIVIVIRMKAQNYPVNEKKIVLPPFFMAT
                     GALMYVVPYFRLTGSEMLEAFIIGLLFSTVLIWTSRFEVKGTEIYMKRSKAFPVILIS
                     LLIIRTVMKIFISNEIDPGELGGMFFLLAFCMIVPWRAAMLYKYKKLKKTLIN"
     gene            7731..8852
                     /locus_tag="RPH49_002363"
     CDS             7731..8852
                     /locus_tag="RPH49_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDY5125483.1"
                     /translation="MKIIHTADWHLGKILNGKQLLEDQAYILDMFVEKMKEEEPDIIV
                     IAGDLYDTTYPSKDAIMLLEQAIGKLNLELRIPIIIISGNHDGKERLNYGASWFEHNQ
                     LFIRTDFTSINSPIEINGVNFYTLPYATVSEMKHYFEDDTIETHQQGITRCIETIAPE
                     IDEDAVNILISHLTVQGGKTSDSERPLTIGTVESVQKGVFDIFDYVMLGHLHHPFSIE
                     DDKIKYSGSLLQYSFSEAGQAKGYRRVTINDGIINDVFIPLKPLRQLEIISGEYNDVI
                     NEKVHVKNKDNYLHFKLKNMSHITDPMMSLKQIYPNTLALTNETFNYNEENNAIEISE
                     KDDMSIIEMFYKHITDKELSDIQSKKIKNILENELRKED"
     gene            8856..>10229
                     /locus_tag="RPH49_002364"
     CDS             8856..>10229
                     /locus_tag="RPH49_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDY5125484.1"
                     /translation="MKPLHLKLNNFGPFLKEEIDFSKIDNNELFLISGKTGSGKTMIF
                     DAMTYALFGKASTEQREENDLRSHFADGKQPMSVTFEFQLNHRIYKVHRQGPYIKEGN
                     TTKTNAKFDVFEMVDGKYEIRESKVISGTQFIIELLGVNADQFRQLFILPQGEFKRFL
                     ISNSREKQGILRTLFDSEKFEAIREILKEEVKKEKAQIENRYQQIDLLWQEIESFDDD
                     NIKGLLEVATQQIDKLIENIPLLQARSKEILASVNESKETAIKEFEIIEKKTLENNIL
                     KDNINQLNKNKIDFVQLKEQQPEIEGIEAKLKLLQDITNLLNYIENREKIETKIANSK
                     KDISKTNNKILNLDCDKRNIDKEKKMLEENGDLIESKISFIDKTRVLFNDINKYQQSY
                     LNIERLRTEGEQLGDELNDLIKGLETVEDSIGNNESDYEKIIELNNTITNINNEINII
                     KENEKAKA"
BASE COUNT         3882 a         1337 c         1823 g         3187 t
ORIGIN      
        1 tacactttaa tcttaaatat gatggtttag aaaatgattt aacaaagaaa tgaaacttta
       61 ctgttgaatt atgtgaggat tgtgttatta tataaatcgt aataattacg atttgataaa
      121 aagtgaggta actatatatg gctaagaaat ctaaaatagc aaaagagaga aaaagagaag
      181 agttagtaaa taaatattac gaattacgta aagagttaaa agcaaaaggt gattacgaag
      241 cgttaagaaa attaccaaga gattcatcac ctacacgttt aactagaaga tgtaaagtaa
      301 ctggaagacc tagaggtgta ttacgtaaat ttgaaatgtc tcgtattgcg tttagagaac
      361 atgcgcacaa agggcaaatt ccaggtgtta aaaaatcaag ttggtaaaat caaatttcgt
      421 actttagccc atttacaata tcaataaaac aatgtacagt atatacgaat gctataaact
      481 gaatgttttc tcatattaat aaggaaacat tcggttttta atttgcattt aaaaaaaatt
      541 agtttttaaa ggggctattt aaagtgaaaa tatttgatta cgaagatatt caattaatac
      601 ctaataaatg catagttgaa agtaggtctg aatgtgatac aacaatccaa tttggtccga
      661 aaaaattcaa gctacctgta gttcctgcaa atatgcaaac agttatgaat gagaaattag
      721 cgaaatggtt tgctgaaaat gattactttt atatcatgca tcgttttgat gaagaagcaa
      781 gaataccttt tataaaacat atgcaaaatt caggcttatt tgcatctatt tcagttggtg
      841 taaagaaagc ggaatttgat tttattgaaa agttagctca agaaaaatta atccccgaat
      901 atattacaat agatattgcg catggtcact cagattcagt gataaacatg attaaacata
      961 taaaaaacca tatacctgat agttttgtta ttgctggtaa tgttggtacg ccaaaaggtg
     1021 ttagagaatt agaaaatgct ggtgctgatg ctaccaaagt cggtataggt cctggtagag
     1081 tttgtattac aaagattaaa acaggttttg gtactggtgg ttggcagtta gcggcattaa
     1141 acatatgtag taaagcagct cgtaaacctt tgattgccga tggtggtata agaacgcatg
     1201 gcgacattgc taaatcaatt agatttggtg catcaatggt catgattggt tcattatttg
     1261 cggcacacga agaatcacct ggtgaaactg tagaacttga tggtaaacag tataaagaat
     1321 attttggtag tgcatctgaa tttcaaaaag gcgaacataa aaatgtagaa ggtaaaaaaa
     1381 tgtttgtaga acataagggt tcattaatgg ataccttaaa agaaatgcaa caagatttac
     1441 aaagctcaat ttcatatgcc ggtggaaaag acttgaaatc attacgtact gtagattatg
     1501 ttattgttag aaactctatt ttcaacggtg atagagatta atatttatag taggtgatgt
     1561 aaattaaaaa attcatagta actgttgttg cgtttttatc aattattatt attgcgccaa
     1621 taacagaatt taaaccattc attcatttac aaaatgaagt aagacaatat attgacattc
     1681 acatcaataa agaaacaatt tctgcggaaa ataaattgga tacgcctaag aaacaacaat
     1741 ttgcctttaa taatattcag atgaatatgt caaagtcaga tgttgagaaa acattgaata
     1801 aaccaaaaag agttacattt aatgaatatg gcacgaagtg gtatacgtat tatgatgacg
     1861 attacaataa ttttatcatg gtaagctata ttaaagataa agtaaatgcg ttatatacaa
     1921 atcaaaatat cattacttca aaatcaaaaa ttaaatacaa tacaccgaaa tcggttgtaa
     1981 tacaaagatt aggcgaacca gagacagaga ttgttaaagg tagagtgcgt tacgaacaaa
     2041 ataataaaga atatgatgtt ttccataaaa atcacattta tacgacggta ttttatgata
     2101 agcatcgacg taataatgta acagctgttt tacaagtaag tgatgctatg gaaaatagat
     2161 taaaagaaca atatggagca ccttcgaaat cgcttgcaga tagttttgaa ctacaaaatt
     2221 ttgatttagt taatgctgaa agaaaacaac atcaattatc tacattgaag tattctaaac
     2281 agaattctga aactgctcgt aagcatagta aagatatggc caacaatcat tattttgatc
     2341 atacaaattt aaaaggtcaa tcaccatttg atcgattgaa aaaagatggt attacattta
     2401 actcagccgg agagaattta gcatatggtc aagttagtag tatctatgca catcaaggat
     2461 taatgaattc tattggtcac agaaaaaata ttttaaatga tacgtttaaa atattaggtg
     2521 ttggtgttga ttttaatgat gaaaaacaac ctttttggac agaaaattat actggttaat
     2581 gtttttggca tgagattaaa gggtaatgtt tgtctgtaag gaagtagata aacatgatga
     2641 caacagataa accaaaagat gcggatatag ttgaacgcgt caaagatata cttaataaaa
     2701 aagaaagaaa aaataataat ggctcgctcc tgtaaattat tacgggggcg agttttaatt
     2761 tgtgtaacat tttgcagaaa tctgtaattc aaaatttata ttaaagaatg agattatcta
     2821 acaattcgca atttctgttt gaactgaatt tagattagaa taaataaaac ctcttgaaaa
     2881 cgtaactttt tcaagaggtc caaaatttat aaaaatgagg gcttaacaat tacgataata
     2941 tataacggtt taaaatatta catttcgcgg tacaaaccaa ttactttccc aattacagca
     3001 acattgtcta ggtaaattgg ctccattgta ctattttcag gttgtaatcg ataacgattt
     3061 ttttctttat agaagcgttt gacagttgct tcatcttcct cggtcatagc aacaataatg
     3121 tctccatttt ctgctatggt ttgactgcga acaattactt tgtctccgtc taatatacca
     3181 gcctcaatca tactgtcgcc tacgacgttt aatatgaata tgtcgctatt gtgtgtcgat
     3241 gttaagtgtt caggtaatgg aaaatattct tcaatatttt ctactgcggt aataggaaca
     3301 cctgctgtga ctttaccaat aactggcaca tgaatcgttt cttccatatt aatattatca
     3361 cttgtttgat cacttacaat ttctatagca cgtggtttcg tcggatctct tcttatatag
     3421 cctttttctt caagacgtga aaggtgacca tgaacagttg aactggatgc taagccaact
     3481 gcttcaccaa tttcgcgaac actaggcgga taacctttca tttgaacaac ttgtttaata
     3541 tagttatata tttcgctttg tcgttttgtt aattctctca tatataggca ctccctaaat
     3601 taatttatat acagtatatc attaattcac aaccaaaaca aacatttgtt cgttaaaata
     3661 ttgacagaga acataagttc tgataaatta ctaatacaaa caaatgttct aggagtgaaa
     3721 atgatgtttt acaataaata taaaaacgta tcaacatata tcatcatatt tttagtttca
     3781 agtgcagcct ttgcaatatt cttgttaagt gcgaacatta gtgctcactc ggaacaagtg
     3841 tacgaaatga ctgaccatca aattaagaac aatacgataa ataaagcata cgaacataaa
     3901 gaccctacaa acaatagcga acaaagagat gggaaagtgt tcgctttaat aaattgatac
     3961 attgtcacaa cgttattttg cctatttttg cgaaatagcg ttttttatta cttttttgct
     4021 gatcttaaat ttgttatatt ttgttaaagt attataatga ttgaataaac aaattgaagg
     4081 taggtttttt aattgagtaa ttctgatttg aatatcgaaa gaattaacga gttagctaaa
     4141 aagaaaaaag aagtaggatt aactcaagaa gaagcaaagg agcaaacagc cttaagaaaa
     4201 gcttatcttg agagttttag aaaagggttt aaacaacaaa ttgaaaatac taaagtaatt
     4261 gatccagaag gtaatgatgt aacacctgaa aaaattaaag agatacaaca aaaaagagat
     4321 aataaaaatt aaatcacaaa tctgtaaaga attttctgac attataactt gaaataagta
     4381 ttttacttat ctttttattt taaaataagt tataatgtat ttgataaaat tgaagaaggg
     4441 aagatacaca agatgtttaa tgaaaaagat caattagctg ttgatacgct acgtgcacta
     4501 agtatcgaca caatcgaaaa agcgaattct ggtcatccag gattacctat gggagctgcc
     4561 ccaatggctt acactttgtg gacacgtcat ctgaatttta atccacaatc taaagattac
     4621 ttcaatagag accgtttcgt attatctgca gggcatggtt cagcattatt gtatagcttg
     4681 ttacatgttt ctggtagttt agaattagaa gaattaaagc aatttagaca atggggttct
     4741 aaaacaccag gtcatcctga atacagacat acagatggtg tagaagttac taccggacca
     4801 cttggacaag gttttgctat gtcagtagga ttagctttag cagaagatca cctagcaggg
     4861 aaatttaata aagaaggata taatgttgta gatcattaca catatgtatt agcttctgac
     4921 ggtgatttaa tggaaggtat atcgcatgaa gcagcttcat ttgctggaca taataaatta
     4981 agtaaattag ttgttttata cgattcaaat gatatttcat tagatggcga attaaacaaa
     5041 gctttttctg aaaacacaaa agctcgtttt gaagcatatg gttggaatta cttactagtt
     5101 aaagatggta atgatttaga agaaattgat aaagcgatta ctacagctaa atctcaagaa
     5161 ggaccaacga ttattgaagt taaaacaaca atcggatttg gttcaccgaa taaagcagga
     5221 actaatggtg ttcatggggc acctttaggt gaagttgaaa gaaaattaac attcgaaaat
     5281 tacggtttag atcctgaaaa acgttttaat gtttcagaag aggtatacga aattttccaa
     5341 aatactatgt taaaacgtgc taatgaagat gaatctcaat ggaattcatt attagaaaaa
     5401 tatgcagaaa catatcctga attagcagaa gaatttaaat tagcgattag tggtaaattg
     5461 cctaaaaatt ataaggatga attaccacgt tttgaactgg gtcataatgg tgcatctcgt
     5521 gctgattctg gtactgttat tcaagcaatc agtaaaactg tcccttcatt ctttggtgga
     5581 tcagcagacc ttgctggttc aaacaaatcc aatgtaaatg atgcaactga ttatagttct
     5641 gaaacacctg aaggtaaaaa tgtgtggttt ggtgtacgtg aatttgctat gggtgctgct
     5701 gtaaatggta tggctgcaca tggaggttta catccatatg gtgcaacatt cttcgtattt
     5761 agtgattatt taaaaccagc gttacgttta tcatcaatta tgggattaaa tgcaacgttc
     5821 atcttcacac atgattcaat tgcagtaggt gaagatggtc ctactcatga accaattgag
     5881 caattagctg gattaagagc cattccaaat atgaatgtta tccgtcctgc tgatggtaat
     5941 gaaacaagag tagcatggga agttgcctta gaatctgaat ctacacctac ttcattagta
     6001 ttgacacgtc aaaacttacc ggtattagat gtaccagaag atgtagttga agaaggcgtt
     6061 cgaaaaggtg cctatacagt ttatggctct gaagagacac cagaattcct attattagct
     6121 tcaggttcag aagttagtct tgcagttgaa gctgctaaag atcttgaaaa acaaggtaaa
     6181 tcagtacgtg ttgtttcaat gcctaactgg aatgcatttg aacaacaatc tgaagaatat
     6241 aaagaatcag ttattccatc aagcgtaaca aaacgtgttg cgattgaaat ggcttcaccg
     6301 cttggatggc ataaatatgt aggtactgca ggtaaagtta ttgctattga cggctttggc
     6361 gcaagtgcac ctggcgattt agtagttgaa aaatatggat atacaaaaga aaatatctta
     6421 aaccaagtta tgagcttata agaataattt ataaagcgag tatgtttaga agtctaggat
     6481 gcataatctt aggcttcttt taaagtgttg aaatttagag tatagcactt aaactacatc
     6541 ataagtgata agttatgaaa gtatactatt tcagattaat ctttaaaagc tctgttataa
     6601 cagcatgatt tttgatatta tttttagtat cgatattaaa atacttgaat aaactagttc
     6661 ttgaaataat gtgatgaatt tagtaaaatt cagtaggata aagaaagcgg gtgaaacaat
     6721 ggcgacttgg ttagcaatta tttttatagt agctgcatta attttaggtt taattggagg
     6781 tttcctttta gctagaaaat atatgatgga ctacttgaag aaaaacccac caatcaacga
     6841 agaaatgctt cgtatgatga tgatgcaaat gggtcaaaaa ccttctcaga agaaaattaa
     6901 tcaaatgatg acgatgatga ataaaaatat ggatcaaaat atgaagagtg cgaaaaagta
     6961 aattcgcaat tgatagaggc tattttccag atatggaaat ggcctctttt tataatcaaa
     7021 ttaataagaa taaatatgtt tattaaaatt aaagttaaca aaatgacgaa tagactgaga
     7081 aatgctataa ttcattttgt atgatttaca gagagtttat ttaacgagaa ggtgtctgcg
     7141 tgctctattt aatattttca atcattgtag ctttatttat gggaactata gttatagtta
     7201 ttcgtatgaa agctcaaaat tatccggtaa atgagaaaaa aatagttttg ccaccgtttt
     7261 ttatggcgac cggtgcattg atgtacgtcg ttccatattt taggctaaca ggatcggaaa
     7321 tgctagaagc ctttataatt ggtttgcttt tttctacagt tctaatttgg acttctcgat
     7381 ttgaagtcaa aggtacagaa atttatatga aacgatctaa agcatttcca gttattttga
     7441 tttcattact tatcattcgt actgtgatga aaatattcat tagtaatgaa atagatcctg
     7501 gagaattagg cggcatgttc tttttattag cattctgtat gattgttcct tggagagcag
     7561 caatgctata taagtacaaa aaactaaaga aaacattaat caattaatta cttttaaaac
     7621 cacttgtgat cgacttctaa atcagtcaat gagtggtttt aattttactt gaaaaggtga
     7681 aatgattata ttaaaataaa agcgaacaaa tgttctatat ggaggcagta atgaaaatta
     7741 tacatacagc agactggcac ttagggaaaa tattaaatgg caaacagctt ttagaagatc
     7801 aagcgtatat tttagatatg ttcgtagaaa aaatgaaaga agaagaacct gatatcattg
     7861 tgatagctgg agatttatat gacacaacat atccaagtaa agatgcaatc atgttattag
     7921 aacaagcgat tggaaagtta aatttagaac tgcgtatacc aataattatt attagtggaa
     7981 atcacgatgg taaagagagg ttaaactatg gggcgagttg gtttgaacat aatcagttat
     8041 ttataagaac agattttaca tcgattaatt caccaataga gataaatggg gttaattttt
     8101 atacactccc ttatgctact gtgagcgaaa tgaaacacta ctttgaagat gacaccattg
     8161 aaacacatca acagggaatt acgcgctgta ttgaaacaat agcaccggaa attgatgaag
     8221 atgccgtcaa tattttaatt agtcatctga ctgttcaagg tggaaagaca tctgattctg
     8281 aaagaccatt aactattgga acggttgaat cagttcagaa aggtgttttt gatatatttg
     8341 attatgtcat gctaggtcac ttgcatcatc catttagtat agaagacgac aaaattaaat
     8401 atagtggctc cttattgcag tattcatttt cggaagcggg tcaagctaaa gggtatagac
     8461 gtgtaacaat taatgatggc attattaacg atgtatttat tcctcttaag ccacttagac
     8521 aattggaaat tatctcaggc gaatataatg atgttattaa tgaaaaagtt catgtgaaaa
     8581 ataaagataa ttatttacat tttaaactta aaaatatgtc tcatattact gatccaatga
     8641 tgagtttaaa acaaatttat cctaatactt tagcgctgac gaatgaaact tttaattaca
     8701 atgaagaaaa taatgctata gaaataagtg aaaaagatga catgtcaatt atcgaaatgt
     8761 tttataaaca tataactgat aaagaattat cggatatcca atctaaaaag ataaaaaata
     8821 ttttagaaaa cgaattgaga aaggaggatt aatgaatgaa accattacat ttaaagttga
     8881 ataatttcgg ccccttttta aaagaagaaa ttgatttttc taaaattgat aataatgaat
     8941 tgtttttaat aagtggtaag actggatcgg gtaaaacaat gatttttgat gcaatgactt
     9001 atgccttgtt tggtaaagca tcaactgaac aaagagaaga aaatgatttg agaagtcatt
     9061 tcgctgatgg taaacagccg atgtcagtaa catttgaatt tcaattaaat catcgaattt
     9121 ataaagtgca tagacaaggc ccttatatca aagaaggtaa tacaacaaaa acgaacgcta
     9181 aatttgatgt atttgagatg gtggatggca agtatgaaat tagagaaagt aaagtaattt
     9241 caggtaccca attcattatt gaattattag gagtaaatgc agatcaattc cgacaattgt
     9301 ttattttgcc tcaaggtgaa ttcaaacgct ttttaatatc aaacagtcgt gaaaagcaag
     9361 ggatattaag aacactgttt gacagtgaaa aatttgaagc tatacgagaa atattaaaag
     9421 aagaagtaaa aaaagaaaaa gctcaaatcg agaatagata tcaacaaatt gaccttttat
     9481 ggcaagaaat tgaatcattt gatgatgaca atataaaagg cttattagag gttgccactc
     9541 aacagataga caaattgatt gaaaatatac cacttttaca agctaggtcg aaagaaatac
     9601 tagcatctgt aaatgaaagt aaagaaactg ctattaaaga atttgaaata atagaaaaga
     9661 aaacattaga aaataatata ttaaaagata atattaatca actcaacaaa aataaaattg
     9721 atttcgttca attgaaagaa caacaacctg aaatagaggg aattgaagct aagttaaagt
     9781 tgttacaaga tattacaaac ctattgaatt atattgaaaa tagagaaaaa attgaaacta
     9841 aaattgctaa tagcaaaaaa gatatttcta aaaccaataa taaaatattg aatcttgatt
     9901 gtgataagcg aaacatagac aaagagaaaa aaatgttaga agaaaatgga gatttaattg
     9961 aaagtaaaat ctcttttatt gataaaacta gagtattatt taacgatatt aataagtatc
    10021 aacaaagtta tctcaatatt gaacgcttga gaactgaggg tgaacaatta ggtgatgaat
    10081 taaatgatct aattaaaggt ttagaaacgg tcgaagattc aataggtaat aacgaaagtg
    10141 attacgagaa aattatcgaa ctaaataata cgataacgaa cataaataat gaaattaata
    10201 taattaaaga aaatgaaaaa gctaaagct
//
LOCUS       DAPSKH010000076         9896 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPSKH010000076 DAPSKH010000000
VERSION     DAPSKH010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9896)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9896)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9896
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.076"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            83..376
                     /gene="esxA"
                     /locus_tag="RPH49_002365"
     CDS             83..376
                     /gene="esxA"
                     /locus_tag="RPH49_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WXG100 family type VII secretion effector EsxA"
                     /protein_id="HDY5125485.1"
                     /translation="MAMIKMSPEEIRAKSQSYGQGSDQIRQILSDLTRAQGEISANWE
                     GQAFSRFEEQFQQLSPKVEKFAQLLEEIKQQLNSTADAVQEQDQQLSNNFGLQ"
     gene            459..3488
                     /gene="esaA"
                     /locus_tag="RPH49_002366"
     CDS             459..3488
                     /gene="esaA"
                     /locus_tag="RPH49_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EsaA"
                     /protein_id="HDY5125486.1"
                     /translation="MKKKNWIYALIVTLIIIIAIVSMIFFVQTKYGDQSEKGSQSVSN
                     KNNKIHIAIVNEDQPTTYNGKKVELGQAFIKRLANEKNYKFETVTRNVAESGLKNGGY
                     QVMIVIPENFSKLAMQLDAKTPSKISLQYKTAVGQKEEVAKNTEKVVSNVLNDFNKNL
                     VEIYLTSIIDNLHNAQKNVGAIMTREHGVNSKFSNYLLNPINDFPELFTDTLVNSISA
                     NKDITKWFQTYNKSLLSANSDTFRVNTDYNVSTLIEKQNSLFDEHNTAMDKMLQDYKS
                     QKDSVELDNYINALKQMDSQIDQQSSMQDTGKEEYKQTVKENLDKLREIIQSQESPFS
                     KGMIEDYRKQLTESLQDELANNKDLQDALNSIKMNNAQFAENLEKQLHDDIVKEPDTD
                     TTFIYNMSKQDFIAAGLNEDEANKYEAIVKEAKRYKNEYNLKKPLAEHINLTDYDNQV
                     AQDTSSLINDGVKVQRTETIKSNDINQLTVATDPHFNFEGDIKINGKKYDIKDQSVQL
                     DTSNKEYKVEVNGVAKLKKDAEKDFLKDKTMHLQLLFGQANRQDEPNDKKATSVVDVT
                     LNHNLDGRLSKDALSQQLSALSRFDAHYKMYTDTKGREDKPFDNKRLIDMMVDQVIND
                     MESFKDDKVAVLHQIDSMEENSDKLIDDILNNKKNTTKNKEDISKLIDQLENVKKTFA
                     EEPQEPKIDKGKNDEFNTMSSNLDKEISRISEKSTQLLSDTQESKSIADSVSGQLNQV
                     DNNVNKLHATGRALGVRANDLNRQMAKNDKENDLFAKEFKKVLQNSKDGDRQNQALKA
                     FMSNPVQKKNLENVLANNGNTDVISPTLFVLLMYLLSMITAYIFYSYERAKGQMNFIK
                     DDYSSKNHLWNNVITSGVIGTTGLIEGLIVGLIAMNKFHVLAGYRAKFILMVILTMMV
                     FVLINTYLLRQVKSIGMFLMIAALGLYFVAMNNLKAAGQGVTNKISPLSYIDNMFFNY
                     LNAEHPIGLALVILTVLVIIGFVLNMFVKHFKKERLI"
     gene            3488..3946
                     /gene="essA"
                     /locus_tag="RPH49_002367"
     CDS             3488..3946
                     /gene="essA"
                     /locus_tag="RPH49_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssA"
                     /protein_id="HDY5125487.1"
                     /translation="MLMNSVIALTFLTASSNNGGLNIDVQQEEEKRINNDLNQYDTTL
                     FNKDSKAVNDAIAKQKKERQQQIKNDMFQNQASHSTRLNETKKVLFSKSNLEKTSESD
                     KSPYIQNKQEKKIFPYILMSVGAFLTLGFVIFSIHKGRRTKNESARKSNI"
     gene            3918..4160
                     /gene="esaB"
                     /locus_tag="RPH49_002368"
     CDS             3918..4160
                     /gene="esaB"
                     /locus_tag="RPH49_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EsaB"
                     /protein_id="HDY5125488.1"
                     /translation="MNQHVKVTFDFTNYNYGTYDLAVPAYLPIKNLIALVLDSLDISI
                     FDVNTQIKVMTKGQLLVENDRLIDYQIADGDILKLL"
     gene            4173..5507
                     /gene="essB"
                     /locus_tag="RPH49_002369"
     CDS             4173..5507
                     /gene="essB"
                     /locus_tag="RPH49_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssB"
                     /protein_id="HDY5125489.1"
                     /translation="MVKNHNPKNEMQDMLTPLDAEEAAKTKLRLDMREIPKSSIKPEH
                     FHLMYLLEQHSPYFIDAELTELRDSFQIHYDINDNHTPFDNIKSFTKNEKLRYLLNIK
                     NLEEVNRTRYTFVLAPDELFFTRDGLPIAKTRGLQNVVDPLPMSEAEFLTRYKALVIC
                     AFNEKQSFDALVEGNLELHKGTPFETKVIEAATLDLLTSFLDEQYQKQEQDYSENYAY
                     VRKVGHTVFKWVAIGMTTLSVLLIAFLAFLYFSVMKHNERIEKGYQAFVKDDYTQVLN
                     TYDDLDGKKLDKEALYIYAKSYIQTNKQGLEKDKKENLLNNVTPNSNKDYLLYWMELG
                     QGHLDEAIDIATYLDDNDITKLALINKLNEIKNNGDLSNDKRSEETKKYNDKLQDILD
                     KEKQVKDEKAKSEEEKAKAKDEKLKQQEENEKKQKEQAQKDKEKRQEAERKK"
     gene            5529..>9896
                     /gene="essC"
                     /locus_tag="RPH49_002370"
     CDS             5529..>9896
                     /gene="essC"
                     /locus_tag="RPH49_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VII secretion protein EssC"
                     /protein_id="HDY5125490.1"
                     /translation="MHKLIIKYNKQLKMLNLRDGKTYTISEDERADITLKSLGEVIHL
                     EQNNQGTWQANHTSINKVLVRKGDLDDITLQLYTEADYASFAYPSIQDTMTIGPNAYD
                     DMVIQSLMNAIIIKDFQSIQESQYVRIVHDKNTDVYINYELQEQLTNKAYIGDHIYVE
                     GIWLEVQADGLNVLSQNTVASSLIRLTQEMPHAQADDYNTYHRSPRIIHREPTDDIKI
                     ERPPQPIQKNNTVIWRSIIPPLVMIALTVVIFLVRPIGIYILMMIGMSTVTIVFGITT
                     YFSEKKKYNKDVEKREKDYKAYLDNKSKEINKAIKAQRFSLNYHYPTVAEIKDIVETK
                     APRIYEKTSHHHDFLYYKLGIANVEKSFKLDYQEEEFNQRRDELFDDAKELYEFYTDV
                     EQAPLINDLNHGPIAYIGARHLILEELEKMLIQLSTFHSYHDLEFLFVTREDEVETLK
                     WARWLPHMTLRGQNIRGFVYNQRTRDQILTSIYSMIKERIQAVRERSRSNEQIIFTPQ
                     LVFVITDMSLIIDHVILEYVNQDLSEYGISLIFVEDVIESLPEHVDTIIDIKSRTEGE
                     LITKEKELVQLKFTPENIDNVDKEYIARRLANLIHVEHLKNAIPDSITFLEMYNVKEV
                     DQLDVVNRWRQNETYKTMAVPLGVRGKDDILSLNLHEKAHGPHGLVAGTTGSGKSEII
                     QSYILSLAINFHPHEVAFLLIDYKGGGMANLFKDLVHLVGTITNLDGDEAMRALTSIK
                     AELRKRQRLFGEHDVNHINQYHKLFKEGIATEPMPHLFIISDEFAELKSEQPDFMKEL
                     VSTARIGRSLGIHLILATQKPSGVVDDQIWSNSKFKLALKVQDRQDSNEILKTPDAAD
                     ITLPGRAYLQVGNNEIYELFQSAWSGATYNIEGDKLEVEDKTIYMINDYGQLQAINKD
                     LSGLEDEETKENQTELEAVIDHIESITTRLEIEEVKRPWLPPLPENVYQEDLVETDFR
                     KLWSDDAKEVELTLGLKDVPEEQYQGPMVLQLKKAGHIALIGSPGYGRTTFLHNIIFD
                     VARHHRPDQAHMYLFDFGTNGLMPVTDIPHVADYFTVDQEDKIAKAIRKIHDIISERK
                     RLLSQERVVNIEQYNKETGNSIPNIFLIIDNYDTVKESPFMEGYEEMMSKVTREGLAL
                     GVYIILSGSRSSAIKSAIFTNIKTRVALYLFENNELTNIIGSYKKGVKDVKGRAAIND
                     DNFTQFQIAQPFELAEGQTYNERIKNEVAQMKEFYVGDYPKHIPMMPDKVLMDDIQET
                     YDLEKIIHEEHKLPLGLDFEDVELVGFDLSQTNIFTSVKPVDIDNGLTLLEKQLNIIS
                     NEYEIATLDTKGILKNTGYEDYLYCGDKKEIISFKNELVSFIKNVEPRKKWIVVISDF
                     KEFINIASPNNDEIKTIFLDGPKNNVFPIIYGLYQETIGGFSSQIKLLKEIVSSAFVG
                     ISISEQELIKVRYKVNEKNL"
BASE COUNT         3911 a         1391 c         1769 g         2825 t
ORIGIN      
        1 atttgagtaa ggagcacttt ttcaaaaaat agtgtcccta aaaagttttg ataaacttaa
       61 aatattcagg aggtttctag ttatggcaat gattaagatg agtccagagg aaatcagagc
      121 aaaatcgcaa tcttacgggc aaggttcaga ccaaatccgt caaattttat ctgatttaac
      181 acgtgcacaa ggtgaaattt cagcgaactg ggaaggtcaa gctttcagcc gtttcgaaga
      241 gcaattccaa caacttagtc ctaaagtaga aaaatttgca caattattag aagaaattaa
      301 acaacaattg aatagcactg ctgatgccgt tcaagagcaa gaccaacaac tttctaataa
      361 tttcggtttg caataagcat tctgaaattg gcaaagtcac attttctaat gtggctttgc
      421 ttatcatttt ttaagaaaac aactgaaagg aaataagcat gaaaaagaaa aattggattt
      481 atgcattaat tgtcacttta attattataa ttgccatagt tagtatgata ttttttgttc
      541 aaacaaaata tggagatcaa tcagaaaaag gatcccaaag tgtaagtaat aaaaataata
      601 aaatacatat cgcaattgtt aacgaggatc aaccaacgac atataacggt aaaaaggttg
      661 agctgggtca agcatttatt aaaaggttag caaatgagaa aaactataaa tttgaaacag
      721 taacacgaaa cgttgctgag tctggtttga aaaatggtgg ataccaagtc atgattgtta
      781 tcccagaaaa cttttcaaaa ttggcaatgc aattagacgc taaaacacca tcgaaaatat
      841 cactacagta taaaacagct gtaggacaaa aagaagaagt agctaaaaac acagaaaaag
      901 ttgtaagtaa tgtacttaat gactttaaca aaaacttggt cgaaatttat ttaacaagca
      961 tcattgataa tttacataat gcacaaaaaa atgttggcgc tattatgacg cgtgaacatg
     1021 gtgtgaatag taaattctcg aattacttat taaatccaat taacgacttc ccggaattat
     1081 ttacagatac gcttgtaaat tcaatttctg caaacaaaga tattacaaaa tggttccaaa
     1141 catacaataa atcattattg agtgcgaatt cagatacgtt cagagtgaac acagattata
     1201 atgtttcgac tttaattgaa aaacaaaatt cattatttga cgagcacaat acagcgatgg
     1261 ataaaatgct acaagattat aaatcgcaaa aagatagcgt ggaacttgat aactatatca
     1321 atgcattaaa acagatggac agccaaattg atcaacaatc aagtatgcaa gatacaggta
     1381 aagaagaata taaacaaact gttaaagaaa acttagataa attaagagaa atcattcaat
     1441 cacaagagtc accattttca aaaggtatga ttgaagacta tcgtaagcaa ttaacagaat
     1501 cactgcaaga tgagcttgca aataacaaag acttacaaga tgcgctaaat agcattaaaa
     1561 tgaacaatgc tcaattcgct gaaaacttag aaaaacaact tcatgatgat attgtcaaag
     1621 aacctgatac agatacaaca tttatctata acatgtctaa acaagacttt atagctgcag
     1681 gtttaaatga ggatgaagct aataaatacg aagcaattgt caaagaagca aaacgttata
     1741 aaaacgaata taatttgaaa aaaccgttag cagaacacat taatttaaca gattacgata
     1801 accaagttgc gcaagacaca agtagtttga ttaatgatgg tgtcaaagtg caacgtactg
     1861 aaacgattaa aagtaatgat attaatcaat taactgttgc aacagatcct cattttaatt
     1921 ttgaaggcga cattaaaatt aatggtaaaa aatatgacat taaggatcaa agtgttcaac
     1981 tcgatacatc taacaaggaa tataaagttg aagtcaatgg cgttgctaaa ttgaaaaagg
     2041 atgctgagaa agatttctta aaagataaaa caatgcattt acaattgtta tttggacaag
     2101 caaatcgtca agatgaacca aatgataaga aagcaacgag tgttgtggat gtaacattga
     2161 atcataacct tgatggtcgc ttatcgaaag atgcattaag ccagcaattg agtgcattat
     2221 ctagatttga tgcacattat aaaatgtaca cagatacaaa aggcagagaa gataaaccat
     2281 tcgataacaa acgtttaatt gatatgatgg ttgaccaagt tatcaatgac atggaaagtt
     2341 tcaaagacga taaagtagct gtgttacatc aaattgattc aatggaagaa aactcagaca
     2401 aactgattga tgacatttta aataacaaaa agaatacaac caaaaataaa gaagatattt
     2461 ctaagctgat tgatcagtta gaaaacgtta aaaagacatt tgctgaagag ccacaagaac
     2521 caaaaattga taaaggcaaa aatgatgaat ttaatacgat gtcttcaaat ttagataaag
     2581 aaattagtag aatttctgaa aagagtacgc aattgctatc agatacacaa gaatcaaaat
     2641 caattgcaga ttctgttagt ggccaattaa atcaagtcga caataatgtt aataagctac
     2701 atgcgacagg tcgagcatta ggcgtaagag cgaatgactt gaaccgtcaa atggctaaaa
     2761 acgataaaga aaatgattta ttcgctaaag agtttaaaaa agtattacaa aattctaaag
     2821 atggcgacag acaaaaccaa gcattaaaag catttatgag taatccggtt caaaagaaaa
     2881 acttagaaaa tgttttagct aataatggta atacagacgt gatttcaccg acattattcg
     2941 tattattgat gtacttacta tcaatgatta cagcatatat tttctatagt tatgaacgtg
     3001 ccaaaggaca aatgaatttc attaaagatg attatagtag taaaaatcat ctttggaata
     3061 atgtcattac gtcaggtgtt attggtacaa ctggtttgat agaaggatta attgtcggtt
     3121 taattgcaat gaataagttc catgtattag ctggctatag agcgaaattc atcttaatgg
     3181 tgattttaac tatgatggtc ttcgtactta ttaatacgta tttactaaga caggtaaaat
     3241 ctatcggtat gttcttaatg attgctgcat tgggtctata ctttgtagct atgaataatt
     3301 tgaaagcagc tggacaaggt gtgactaata aaatttcacc attatcttat atcgataaca
     3361 tgttcttcaa ttatttaaat gcagagcatc ctataggctt ggcgctagta atattaacag
     3421 tacttgtgat tattggcttc gtactgaaca tgtttgtaaa acactttaag aaagagagat
     3481 taatctaatg ttgatgaata gcgtgattgc tttaactttt ttaacagcat ctagcaataa
     3541 tggcggactt aatattgacg tgcaacaaga agaggaaaag cgaatcaata atgatttaaa
     3601 tcaatatgat acaacgctat ttaataaaga cagcaaagcg gttaatgatg cgattgctaa
     3661 gcagaaaaaa gaaagacaac aacaaataaa aaatgatatg tttcaaaatc aagcgagtca
     3721 ctcgactcgc ttgaatgaaa ctaaaaaagt gttattttcc aaatctaact tagaaaagac
     3781 ttcggagagt gataaaagcc cctatattca aaacaagcag gagaaaaaaa tattcccgta
     3841 cattttgatg tctgtagggg cttttttgac tttaggattt gtcatttttt caattcataa
     3901 agggagacga acgaaaaatg aatcagcacg taaaagtaac atttgatttt actaattata
     3961 attacggcac atatgactta gcagtaccag catatttacc gattaagaat ctaatagcat
     4021 tagtgttaga cagtttggat atttcgattt tcgatgtgaa tacacaaatt aaagtgatga
     4081 cgaaaggtca attacttgtt gaaaacgacc gacttattga ttatcaaatc gctgatggag
     4141 atattttgaa gttactatag gaggaaaaat agatggttaa aaatcataac cctaaaaatg
     4201 aaatgcaaga tatgttaaca cctttagatg ccgaagaagc agctaaaaca aaattacgtt
     4261 tagatatgag agagattcct aagtcttcaa ttaaaccaga acattttcat ttaatgtact
     4321 tattagaaca acattctcca tattttatag atgctgaact aactgaacta cgtgatagtt
     4381 tccaaataca ttatgacatt aatgacaatc atacaccttt tgataatatt aaatcattta
     4441 ctaaaaatga aaaattacgt tacttactta atatcaaaaa tttagaagaa gtaaatcgta
     4501 cacgctacac atttgtgttg gcaccagatg aattattttt cacaagagat ggattgccga
     4561 ttgccaaaac gagaggatta caaaatgttg ttgacccttt gccaatgtcg gaagctgaat
     4621 ttttaacaag atataaagca ctggttatat gtgcattcaa tgagaaacaa tcatttgacg
     4681 cattagttga aggaaactta gaactacata aaggaacacc atttgaaact aaagttattg
     4741 aagcggcaac gttagactta ttaacttcgt ttttagatga acaatatcag aaacaagaac
     4801 aagattatag tgaaaattat gcatatgttc gtaaagtagg gcataccgtt tttaaatggg
     4861 tcgctatcgg tatgacaacg ttaagtgtgt tattaattgc atttttagct tttttatatt
     4921 tttcagtaat gaagcataat gagcgcattg aaaaaggata ccaagcattt gtaaaggatg
     4981 attatacgca agtactaaat acgtatgatg atttagatgg taaaaaatta gacaaagaag
     5041 cgctttacat ttatgccaaa agctatatcc aaacgaacaa acaaggttta gaaaaagata
     5101 agaaagaaaa cttgcttaat aatgtgacgc caaattcgaa caaagattac ttattatatt
     5161 ggatggaatt aggacaagga catcttgatg aagcgattga cattgcaaca tatttagatg
     5221 ataacgatat tacgaaatta gcgttgatta ataaattaaa tgagattaaa aataatggtg
     5281 atttatcgaa tgataaacgt tctgaagaaa ctaaaaaata taacgataaa ttgcaagata
     5341 ttttagataa agaaaagcaa gttaaagatg aaaaagcaaa atctgaagaa gagaaagcaa
     5401 aagcgaaaga tgagaaatta aagcaacaag aagagaacga aaagaaacaa aaagaacaag
     5461 cacaaaaaga taaagaaaaa cgtcaagaag ctgaaagaaa aaaatagtat aggactgagg
     5521 caaagacaat gcataaattg attataaaat ataacaaaca attgaagatg ctcaatttgc
     5581 gagatggtaa gacatatact attagcgaag acgagcgtgc agatattacg ttgaaatcgt
     5641 taggcgaagt cattcattta gaacaaaata atcaaggtac ttggcaagcg aatcatactt
     5701 ctattaataa ggtgcttgtt agaaaaggtg accttgatga cattacatta caactttata
     5761 cagaagctga ttatgcatca tttgcttatc cttcaattca agatacgatg acaattgggc
     5821 caaatgcgta tgatgatatg gttattcaaa gcttgatgaa tgccatcatt attaaagatt
     5881 ttcaatcaat acaagaatca caatacgtac gcattgtgca cgataaaaat acagatgtgt
     5941 atattaacta tgaactacaa gagcaattaa caaacaaagc ttacattggt gatcatattt
     6001 atgttgaagg gatatggctc gaagtacaag ctgatggttt aaatgtattg agtcagaata
     6061 cagtggcatc gtcattaatt cgcttaacac aagagatgcc acatgcacag gcagatgatt
     6121 acaatacgta ccatcgttcg ccaaggatta ttcaccgtga accgaccgat gatattaaga
     6181 ttgaaagacc accacagcca atacagaaga acaatacagt gatatggcgt tccattatac
     6241 cgccattagt aatgattgct ttaactgttg tcatcttttt agtgagacca attggtattt
     6301 atattttaat gatgattggt atgagtacag taacgatagt atttggtatt acaacgtatt
     6361 tctctgaaaa gaaaaagtat aacaaagatg ttgaaaaacg agagaaagat tacaaagctt
     6421 atttggataa taaatctaaa gaaattaata aagcgattaa agcacaacgt tttagtttga
     6481 attatcatta tccaacggtt gctgaaatta aagatatcgt tgaaacgaaa gcaccaagaa
     6541 tatatgaaaa aacatcgcat catcacgatt tcttatatta taagttaggt attgcgaatg
     6601 tagaaaagtc attcaaatta gattaccaag aagaagaatt taaccaacgt cgtgatgaac
     6661 tattcgacga tgctaaagaa ttgtatgaat tttacacaga tgtagaacaa gcaccattaa
     6721 tcaatgattt aaatcatggg ccaattgcat atattggtgc acgacatctc attttagaag
     6781 aattggagaa aatgctaatc caattgtcaa cgttccatag ttatcatgat ttagagtttc
     6841 tatttgtgac acgtgaagat gaagttgaaa cattgaaatg ggcacgttgg ttgccacata
     6901 tgacattgag aggtcaaaac attagagggt ttgtttacaa tcaacgaaca cgtgaccaaa
     6961 ttttaacgtc aatttatagc atgattaaag aacgtatcca agctgtgcgt gaacgcagca
     7021 gaagtaatga gcaaattatt ttcacaccgc aattagtgtt tgtcattaca gatatgtcat
     7081 taattattga tcacgtcatt ttagaatatg taaaccaaga tttatcagaa tatggtattt
     7141 cattaatctt tgttgaagat gtgattgaaa gtttgccaga gcatgtagat accattattg
     7201 atatcaagtc tcgtactgaa ggcgaactga ttacgaaaga aaaagaatta gttcaattga
     7261 aatttacacc tgaaaatatt gataacgtcg ataaagaata tatcgcgcga cgtttggcga
     7321 atttgataca cgtcgaacat ttgaaaaatg caattcctga tagtattaca tttttagaaa
     7381 tgtataacgt gaaagaagta gatcagcttg atgtggttaa tcgatggaga caaaacgaaa
     7441 catacaaaac gatggcagta cctttaggtg taagaggtaa agatgacatt ttatcattga
     7501 acttacatga aaaagcacac ggaccacatg gtttagttgc tggtaccact ggttcaggga
     7561 aatctgagat tatccaatca tacattttat ctttagctat taattttcac ccgcatgaag
     7621 ttgcattcct attgattgac tataaaggtg ggggtatggc gaacttattt aaagatttag
     7681 tccatttagt tggtacgatt acaaacttag atggcgatga agcgatgcgt gccttaacat
     7741 caatcaaagc cgaattgaga aaacgtcaac gtttattcgg agagcatgat gttaaccata
     7801 ttaatcaata ccataagtta tttaaagaag gtattgcgac agaaccaatg ccacatttat
     7861 tcattatttc cgatgaattt gccgaattaa aatcagaaca acctgatttt atgaaagaac
     7921 ttgtatcaac ggcacgtatt ggacgttcgt taggtattca tttaatactt gcgacacaaa
     7981 aaccatcggg tgttgttgat gaccaaattt ggtctaactc taaatttaaa ttggcattaa
     8041 aagtacaaga tagacaagac agtaatgaaa ttttaaaaac accagatgca gcagacatta
     8101 cattaccagg tcgcgcgtat ttacaagttg gtaataatga aatttatgaa ttgttccaat
     8161 ctgcatggag tggagcaaca tataacatcg aaggcgataa attagaagtt gaagataaga
     8221 cgatttacat gattaatgac tatggtcaac ttcaagcaat caacaaagac ttgagtggac
     8281 ttgaagatga agaaacgaaa gaaaatcaaa ctgagttaga agcggttatc gatcatatcg
     8341 aatctattac aacacgatta gaaattgaag aagttaagcg tccatggtta ccaccattac
     8401 cagaaaatgt atatcaagaa gatttagtag aaacagattt cagaaaatta tggtcagatg
     8461 atgcaaaaga agtggaatta acattaggac ttaaagacgt accagaagaa caatatcaag
     8521 ggccgatggt attacaattg aaaaaagctg gtcacatcgc gttaatcgga agtccaggat
     8581 atggtagaac aacgttctta cacaacatta ttttcgatgt tgcaagacac catcgtcctg
     8641 atcaagcaca catgtacttg ttcgatttcg gaactaatgg tttgatgcca gtcacagaca
     8701 taccacatgt tgctgattat tttacagtag atcaagaaga caagattgcg aaggcgatac
     8761 gtaagataca tgatattatt tctgagcgaa aaagactatt aagtcaagag agagtagtta
     8821 atatagagca atataataaa gaaactggaa attcaattcc aaatattttc ttaattatcg
     8881 ataactacga cacggtgaaa gaatcaccat ttatggaagg atatgaagaa atgatgtcta
     8941 aggtaacacg tgaaggttta gcattagggg tatacatcat tctttcagga tcaagatcaa
     9001 gtgcaataaa atcagctata tttactaaca ttaaaacaag agttgcacta tacctctttg
     9061 aaaataatga attaacaaat attattggtt cttataaaaa aggtgtgaaa gatgttaaag
     9121 gtagagctgc aataaatgat gataacttca cacagttcca aattgcgcaa ccatttgaat
     9181 tagcagaagg acaaacatat aacgagcgca ttaaaaatga agtagcacaa atgaaagaat
     9241 tctatgtagg agattatcca aaacatatcc caatgatgcc agataaggta ttaatggatg
     9301 atattcaaga aacatatgat ttggaaaaaa tcattcatga agaacacaaa ttaccattag
     9361 gattagactt tgaggatgtg gaactagttg gtttcgactt aagtcaaaca aatattttca
     9421 cttcagttaa acctgttgat atagataatg gtttaacttt attagagaaa cagctaaata
     9481 taatttcaaa tgaatatgaa attgcaactt tagacacaaa aggcatatta aaaaatacag
     9541 ggtatgaaga ttatttgtac tgtggagata agaaagaaat tattagtttt aaaaatgaat
     9601 tagtgagttt tataaaaaat gtagaaccac gaaaaaaatg gatagtagtt atatcggatt
     9661 ttaaagaatt tataaatatt gcatcaccaa ataatgatga aataaaaact atatttttag
     9721 acggaccaaa gaataatgtc tttccaatta tttacggatt gtatcaagaa acaattggag
     9781 gatttagttc tcaaataaag ttacttaagg aaatagtcag tagcgctttt gtaggaatta
     9841 gtattagcga acaagaatta ataaaagttc gttataaagt aaatgaaaaa aacctt
//
LOCUS       DAPSKH010000077         9824 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPSKH010000077 DAPSKH010000000
VERSION     DAPSKH010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9824
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.077"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            129..962
                     /locus_tag="RPH49_002371"
     CDS             129..962
                     /locus_tag="RPH49_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDY5125491.1"
                     /translation="MNKTVKDLILVVLGSFIFAAGVNAFIISGNLGEGGVTGLAIILY
                     YAFHISPAITNFLVNAVLIAIGYKFLSKRSMYLTILVTILISIFLSLTESWQVETGNS
                     IVNAIFGGVSVGLGIGVIILAGGTTAGTTILARIATKYLDVSTPYALLFFDMIVVAIS
                     LTVIPLDKVLVTVISLYIGTKVMEYVIEGLNTKKAMTIISTNPDKLAKAIDEQIGRGL
                     TILNGHGYYTREEKDVLYVVISKTQVSKAKRLIKQIDKDAFLVIHDVRDVYGNGFLAD
                     E"
     gene            1243..2040
                     /locus_tag="RPH49_002372"
     CDS             1243..2040
                     /locus_tag="RPH49_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125492.1"
                     /translation="MNRLHGQQVKIGYGDNTIINKLDVEIPDGKVTSIIGPNGCGKST
                     LLKALSRLLAVKEGEVFLDGENIHTQSTKEIAKKIAILPQSPEVADGLTVGELVSYGR
                     FPHQKGFGRLTAEDKKEIDWAMEVTGTDTFRHRSINDLSGGQRQRVWIAMALAQRTDI
                     IFLDEPTTYLDICHQLEILELVQKLNQEQGCTIVMVLHDINQAIRFSDHLIAMKEGDI
                     IATGSTEDVLTQEILEKVFNIDVVLSKDPKTGKPLLVTYDLCRRAYS"
     gene            2076..3080
                     /locus_tag="RPH49_002373"
     CDS             2076..3080
                     /locus_tag="RPH49_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDY5125493.1"
                     /translation="MTNRENPTPLKFLYYIIGLSMILLIILFISTLIGDAKIQASTII
                     EAIFNYNPSNQQQNIINEIRIPRNIAAVIVGMALAVSGAIIQGVTRNGLADPALIGLN
                     SGASFALALTYAVLPNTSFLILMFAGFLGAILGGAIVLMIGRSRRDGFNPMRIILAGA
                     AVSAMLTALSQGIALAFRLNQTVTFWTAGGVSGTTWSHLKWAIPLIGIALFIILTISK
                     QLTILNLGESLAKGLGQNVTMIRGICLIIAMILAGIAVAIAGQVAFVGLMVPHIARFL
                     IGTDYAKILPLTALLGGILVLVADVIARYLGEAPVGAIISFIGVPYFLYLVKKGGRSI
                     "
     gene            3077..4093
                     /locus_tag="RPH49_002374"
     CDS             3077..4093
                     /locus_tag="RPH49_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDY5125494.1"
                     /translation="MISSNNKRRRWIALAVFSILLFLGCTWSITSGEYNIPVERFFKT
                     LIGQGDAIDELILLDFRLPRMMITILAGAALSISGAIVQSVTKNPIAEPGILGINAGG
                     GFAIALFIAIGKINADNFVYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGV
                     GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFK
                     SNTLNIIHTGDNIARGLGVRLSRERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAK
                     RIVGPRHQLFLPIAILVGACLLVIADTIGKIVLQPGGVPAGIVVAIIGAPYFLYLMYK
                     TKNV"
     gene            4327..5295
                     /gene="dhaK"
                     /locus_tag="RPH49_002375"
     CDS             4327..5295
                     /gene="dhaK"
                     /locus_tag="RPH49_002375"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDY5125495.1"
                     /translation="MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKDKKEHG
                     VAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVV
                     KNYAGDVMNFEMAQELAEMEGINVETVIVRDDIAVTNEAQRRGVAGTVFVHKLAGYLS
                     EKGLALGEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKG
                     IHREEVKDIDHIVRTLLDELYKEVTANEVIVMVNGMGGTPLSELNIVTKYIQQNLTAR
                     TVNVVKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQYFK"
     gene            5337..5921
                     /gene="dhaL"
                     /locus_tag="RPH49_002376"
     CDS             5337..5921
                     /gene="dhaL"
                     /locus_tag="RPH49_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDY5125496.1"
                     /translation="MKVNDMKARLLNLEETFKKHESELTELDRAIGDGDHGVNMVRGF
                     SSLKEKLDDSSMQSLFKSTGMALMSNVGGASGPLYGFSFVKMSAVTKDDMDNQDFTTL
                     IQAFAEAVESRGKVTLNEKTMYDVVARAAEKLKNGETLTFNDLQQLADNTKDMVATKG
                     RAAYFGEESKGYIDPGAQSMVYILNALIGDEDNA"
     gene            5914..6276
                     /locus_tag="RPH49_002377"
     CDS             5914..6276
                     /locus_tag="RPH49_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDY5125497.1"
                     /translation="MPKIILVSHSKEIANGTKSLLKQMAGDVDIIPIGGLPDGSIGTS
                     FDIIQEALTELDDDAMCFYDIGSSEMNVDMAIEMYDGNHRVLKVDAPIVEGSFIAAVK
                     LSIGGSIDDALAEIKQSF"
     gene            6392..6889
                     /locus_tag="RPH49_002378"
     CDS             6392..6889
                     /locus_tag="RPH49_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125498.1"
                     /translation="MQHLIKKHVLNGEFDLVRQLMSETDFMEFEEAYISSAHEVESMM
                     FYTCILDMIKYEESSEMHDLAFLLLVYPLSEYEGALDSAYYHADASIKLTDGKEVKSL
                     LQMLLLHAIPTPVISDKKAFDIAKQILKLDPNNNVARNVLKDTAKRMDNVVVDINELH
                     QRNAR"
     gene            7346..8413
                     /locus_tag="RPH49_002379"
     CDS             7346..8413
                     /locus_tag="RPH49_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125499.1"
                     /translation="MMMNKEATKIGFAYVGIVVGAGFSTGQEVMQFFTKYGLWAYLGV
                     IISGFILAFIGRQVAKIGTAFEATNHESTLQYVFGEKFSKVFDYILIFFLFGIAVTMI
                     AGAGATFEESYNIPTWLGALIMTLAIYVTLLLDFNKIVRALGVVTPFLIVLVVLIAGV
                     YLFKGHVSLAEVNQVVPEASIWKGIWFGTIYGGLAFSVGFSTIVAIGGDTEKRTVSGA
                     GAMYGGIIYTVLLALINFALQSEYPTIKNASIPTLTLANNIHPLIATVLSVIMLAVMY
                     NTILGLMYSFAARFTEPYSKNYHIFIIIMMVAGYLLSFVGFAELINKLYTIMGYVGLF
                     IVVAVIIKYFKRKNADKKHIA"
     gene            8564..9607
                     /locus_tag="RPH49_002380"
     CDS             8564..9607
                     /locus_tag="RPH49_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDY5125500.1"
                     /translation="MNRDNKWTMITALFITVISVLLAFHLKQHYDQTTNENHANKDKI
                     NIKNKNVRIYQNLTYNRVFPNSKLDIITPVDMSSNAKLPVIFWMHGGGYIAGDKQYKN
                     PLLAKIAEQGYIVVNVNYALAPQYKYPTPLIQMNQATQFIKENKMNLPIDFNQVVIGG
                     DSAGAQLASQFTAIQTNDRLRKAMKFDQSFKPSQIKGAILFGGFYNMQTVRETEFPRI
                     QLFMKSYTGEEDWEKSFKNISQMSTVKQSTKNYPPTFLSVGDSDPFESQNIEFSKKLQ
                     ELNVPVDTLFYDGTHHLHHQYQFHLNKPESIDNIKKVLLFLSRNTSSSGIQTEEKPQI
                     ENPSNELPLNPLN"
BASE COUNT         3341 a         1369 c         1875 g         3239 t
ORIGIN      
        1 aaagctattt ttcatataaa ttagttaaat agtaaatctt tgttagaact ctttccatag
       61 agttgtgaca gcatttttgt tgtgctacta tttttatagt ctaataaata tataaagggg
      121 atggtttcgt gaataaaacg gttaaagatt taatactagt tgtcttaggt tcatttatct
      181 ttgctgcagg tgtaaatgca tttattattt ctggtaactt aggtgaaggc ggggttacag
      241 gtttagcaat tattttatat tatgcgtttc atatttcacc agccatcact aacttcttgg
      301 tcaacgcagt attgattgcc ataggttata aatttttgag taagagaagt atgtacttaa
      361 ctattcttgt aacaattctt atttcaatat ttttgagttt aacagaatca tggcaagttg
      421 aaactggaaa cagcattgtg aatgccattt ttggtggtgt aagcgttgga ctaggaatcg
      481 gagtaattat ccttgcaggc ggtacaacag caggtacaac aattttggcg agaattgcaa
      541 cgaaatacct cgatgtaagc acgccatatg ctttgctttt cttcgatatg atcgttgttg
      601 caatttcact tacagttatt ccacttgata aagtattagt aacagtaata tcactttata
      661 taggaacaaa agtgatggaa tatgtcatag aaggtttaaa cactaaaaaa gctatgacga
      721 ttatttcaac taatcccgac aaacttgcca aagcaataga cgagcaaatt ggaagaggtt
      781 taaccatttt aaacggacat ggctattata cgcgtgaaga aaaagatgtc ttatacgttg
      841 ttatttctaa aacacaagtt tcaaaagcaa agcgattaat taaacaaatc gataaagatg
      901 cattccttgt aattcatgat gtaagagatg tctatggtaa tggctttctt gcagatgaat
      961 aaataaatgg tatgagcaca catacttaaa tagaagtcca cggacaagtt tttgaactat
     1021 gaagacttat ctgtgggcgt tttttatttt ataaaagtaa tatacaagac atgacaaatc
     1081 gagctatcca atttaaaaag taatgttagt caataagatt gaaaaatgtt ataatgatgt
     1141 tcatgataat cattatcaat tggggtgcct ttgaaaattg ataatttaaa aatagaaatt
     1201 attttttata aacagaaaga atttaatgaa agtagggaaa ttatgaatcg tttgcatgga
     1261 caacaagtta aaattggtta cggggataac acgattataa ataaattaga tgttgaaata
     1321 ccagatggca aagtgacgtc aatcattggt cctaacggct gcgggaaatc tactttgcta
     1381 aaggcattgt cacgtttatt ggcagttaaa gaaggtgaag tatttttaga tggtgaaaat
     1441 attcatacac aatctacgaa agagattgca aaaaaaatag ctattttacc tcaatcacct
     1501 gaagtagcag atggcttaac tgttggagaa ttagtttcat atggtcgttt tccacatcaa
     1561 aaaggatttg gtagattaac tgctgaggat aagaaagaaa ttgattgggc aatggaagtt
     1621 acaggaactg atacatttcg acaccgttca atcaatgatt taagtggtgg tcaaagacaa
     1681 cgtgtttgga ttgcaatggc attagcacaa agaactgata ttatcttttt agacgaacca
     1741 acaacatatt tagatatctg tcatcaatta gaaatactag aattagttca gaagttaaat
     1801 caggaacaag gttgtacaat tgtcatggtt cttcatgata ttaaccaagc gattcgtttc
     1861 tcagatcatc ttattgcgat gaaagaaggc gatatcatcg ctacaggttc aacagaagac
     1921 gtattaacac aggaaatttt agaaaaagtt tttaatattg atgttgtttt aagtaaagat
     1981 cctaaaactg gaaaaccttt actggtaact tatgacttat gtcgcagagc ttattcttaa
     2041 ttaagtaagt taatatgata aaaaggacaa ttaacatgac aaatagagag aatccaacgc
     2101 cattgaagtt tttatactat attataggtt taagtatgat actactaatc atactattta
     2161 tttctacatt aataggtgac gccaaaattc aagcctctac aattatagag gctattttta
     2221 attataatcc tagcaatcag cagcaaaaca tcatcaatga gattaggatt cccagaaata
     2281 tagcagcagt aattgtgggt atggcgcttg cagtttctgg tgcgattata caaggtgtta
     2341 ctcgtaatgg tcttgctgat ccggcgctca taggtttaaa ttcaggtgct tcatttgctt
     2401 tagcattaac atatgcagtt ttaccaaaca cttcattttt aatattgatg tttgctggat
     2461 ttttaggtgc tattctagga ggggctattg tattaatgat aggccgatct agacgtgatg
     2521 gatttaatcc gatgcgtatt attttagcgg gtgcagcagt aagtgctatg ttaacagcgc
     2581 taagtcaagg tattgcatta gcttttagac taaatcaaac agtaacattt tggactgctg
     2641 gaggcgtttc aggcacaaca tggtcacacc ttaagtgggc aattccatta attggaattg
     2701 cgttattcat tatattaaca attagtaaac aacttaccat tttaaatctt ggtgaatcat
     2761 tagctaaagg tttaggtcaa aatgtaacaa tgatcagagg catatgttta attattgcta
     2821 tgattctagc aggtatagca gttgctatcg ctggacaagt tgcatttgta ggtttgatgg
     2881 tacctcatat agcaagattt ttaattggaa ctgattatgc taaaattcta ccattaacag
     2941 ccttgttggg tgggatactc gtgcttgttg ccgatgtgat agcacgatat ttaggagaag
     3001 cgcctgttgg tgcaatcatt tcatttatcg gtgttcctta ctttttatat ttagttaaaa
     3061 aaggaggacg ctcaatatga ttagttcaaa taataaacgc agacgatgga ttgcactggc
     3121 tgtttttagc attctactat ttctaggttg tacttggagt atcacctcag gtgaatacaa
     3181 cataccagtt gaaagatttt tcaaaacttt aattggacaa ggtgatgcca ttgatgagct
     3241 aatcttatta gatttcaggt tacctcggat gatgattact attttggcag gcgcagcgct
     3301 tagtattagt ggtgcaatag tgcaaagtgt cacaaaaaat ccaatagctg aacccggtat
     3361 attaggtatt aatgcaggcg gcggatttgc aatcgcatta tttattgcaa ttggtaaaat
     3421 taatgctgac aactttgttt atgtactgcc gttaataagt atactaggtg gtatcaccgc
     3481 tgcattgatt atttttattt tcagttttaa taaaaatgaa ggtgttacac ctgcgagtat
     3541 ggtattaata ggtgtaggtt tacaaacagc attgtatggt ggctcaatta caattatgtc
     3601 aaaatttgat gataagcaat ctgatttcat cgctgcttgg tttgcaggta atatttgggg
     3661 tgacgaatgg ccatttgtca ttgcattttt accgtgggtg ttgattatta ttccttactt
     3721 actatttaaa tcgaatacac taaatattat tcatacgggt gataatattg cacgaggtct
     3781 aggtgtaagg ttaagcagag aacgtttaat attattcttt atcgcagtga tgttatcatc
     3841 tgctgctgta gcagtagcag gttcaatttc gtttatcgga ttaatgggcc cgcatattgc
     3901 caaacgtatc gttggaccac gtcaccagtt gtttttacca attgccattt tagtaggggc
     3961 atgtttactt gttatagctg atacaattgg caaaattgta ttacaaccag gtggggttcc
     4021 agcaggtatt gtcgtagcaa ttattggtgc accgtatttc ttatatttaa tgtacaaaac
     4081 gaaaaacgta tagtgtcaaa ggacacaaca tattgctatg aaaggcactt tattataagg
     4141 cttttcatag cattttttat ttaatgagtc actcaagact atttactttt tcaataatga
     4201 accattaagt tatcaagagg atcttatcaa aaatatattt gataacggta tcaggttaac
     4261 cctttatgat agcgcattca tttattctgt tttatactat gactgataat accaaggagg
     4321 tacaacatga tgaaaaagtt aatcaataaa aaagaaacat ttttaactga tatgcttgaa
     4381 ggattgttaa ttgcgcaccc agagttagat ctgattgcta atacagttat tgtaaaaaaa
     4441 gataagaaag aacatggtgt agcaatagtc tctggaggtg gaagcggaca tgaacctgcg
     4501 catgccggtt ttgttgcaga aggtatgcta gatgcagcgg tttgtggcga ggtatttact
     4561 tcacctacac cagataaaat attagaagct attaaagcag tagatacagg tgatggtgta
     4621 ttactagttg tgaaaaacta tgcaggtgac gtgatgaatt ttgaaatggc acaagagctt
     4681 gcagaaatgg aaggtataaa tgttgaaaca gttattgttc gtgacgacat tgctgtgaca
     4741 aatgaagcac aacgtcgtgg tgttgcagga acagtgtttg ttcataagct tgccggttat
     4801 ctttcagaaa aagggctcgc attaggcgag attaaatcgc gtgtagaagc gttgttacct
     4861 gaaattaaaa gtattggtat ggcaattgag ccaccgcttg ttccaactac tggaaaatat
     4921 ggctttgata ttgaagacga caaaatggaa attggcattg gtatacatgg tgaaaaaggt
     4981 attcataggg aagaagtaaa ggatattgat catattgtta gaacattatt agacgaattg
     5041 tataaagaag ttactgccaa tgaggtcata gtaatggtaa atggaatggg aggtacgccg
     5101 ttatctgaat taaatatcgt aactaaatat attcaacaaa atttaactgc aagaacggtt
     5161 aatgttgtta aatggtttgt tggtgattat atgacatctt tagacatgca aggtttttct
     5221 ataactatcg tgcctaataa accagaatat ctggaagcat ttttagcacc aacaacaagt
     5281 caatacttta aataagcagt gaatatgaat aaatatacat ttatgaggtg gcacaaatga
     5341 aagtgaatga tatgaaagcg cgtttattaa atttagaaga aacgtttaaa aaacatgaat
     5401 ctgaattaac tgaattagat cgagcaattg gtgatggtga ccacggggtt aacatggttc
     5461 gagggtttag tagtcttaaa gaaaaacttg atgatagctc aatgcaatca ttgttcaaat
     5521 cgactggtat ggcattgatg tcaaatgttg gcggtgcatc aggaccactg tatggcttta
     5581 gctttgttaa aatgtctgca gttactaaag atgatatgga taatcaagat ttcactacac
     5641 taattcaagc atttgccgaa gcggtcgaat cacgtgggaa agttacttta aatgaaaaga
     5701 caatgtatga tgtagtagca cgagcagcag agaagcttaa aaatggtgaa actttaacat
     5761 ttaatgattt acaacaatta gcagataata caaaagatat ggtagcaacg aaaggtagag
     5821 ctgcatattt tggagaagaa tcaaaaggtt atatagatcc aggtgctcaa agtatggttt
     5881 atattttaaa cgctttgata ggagatgaag ataatgccta aaattatact tgttagccat
     5941 agtaaagaaa ttgcaaatgg tacaaaatct ttgttaaagc aaatggctgg tgacgttgat
     6001 attataccaa tcgggggatt accagatggt tcaattggaa cttcatttga tatcattcaa
     6061 gaagctttaa ctgaattaga tgatgatgca atgtgttttt acgatattgg atcttcagaa
     6121 atgaatgtag atatggcaat tgaaatgtat gatggtaatc atcgtgtgtt aaaagttgat
     6181 gcaccaattg ttgaaggcag ttttatcgca gcagtaaagc tgtcaatcgg cggttcaatt
     6241 gatgatgcat tagcagaaat caaacaatca ttttagttaa aatttactaa taatgaaaaa
     6301 tgtaaacctt tttcaaatga aactttataa aaaatatgat agtatatatg taaatgttta
     6361 ataaaatctg gagaaatagg aggacattgc catgcaacac cttataaaaa aacatgtatt
     6421 gaatggcgag tttgatttag tacgacaatt gatgtccgaa acagatttta tggaatttga
     6481 agaagcatat atttcaagtg cgcatgaagt agaaagtatg atgttttata catgtatttt
     6541 agatatgatt aagtacgaag aatcatctga aatgcatgac ttagcatttt tattgcttgt
     6601 gtatccacta agtgaatatg aaggtgcttt ggattctgct tattatcatg cagacgcttc
     6661 cataaaactt actgacggca aagaagttaa aagtttgtta caaatgttat tattgcatgc
     6721 gataccaaca cctgttattt cagataagaa ggcttttgat atcgccaagc aaattttaaa
     6781 attagatcct aataataatg ttgctcgtaa cgtcttaaaa gacactgcca aacgtatgga
     6841 caacgttgtt gttgatataa atgaattaca ccaacgtaat gcacgttaat tacatttcaa
     6901 ttatattagc ttaataatag ttttaacatt tggttgggtt gggacatatg ttccagcctt
     6961 tttttatact taaaaactaa cgaagtgtac ttgtgtgcac aaatggtttt tatacaacat
     7021 tttataaatt tatacatttt aataaagaac atacgataga tggtttaaac cttattaact
     7081 gagagatttt gatatgtatt tttcgaaatt taactaaaaa tacgtaagtt aagaagcaca
     7141 attattaatc atttttccta tacaaaggtt cgtatgactg cattataaaa gcataaattt
     7201 ataatttttt taaatgtcat tgaacgtgat aatgtgaatg gattgagcaa ttttgaaaaa
     7261 gtgaaaaata acctatgtga cttgcaatta attttcagta cgttataatg cacactgtgc
     7321 aaaattaagg aggtctatta ttcacatgat gatgaataaa gaagcaacaa aaattggatt
     7381 tgcctacgtc ggcattgtag tgggcgcagg attttcaaca ggacaagaag ttatgcaatt
     7441 tttcactaaa tatggcttgt gggcttattt gggtgtgatt atatctggtt ttattttagc
     7501 ttttattggg cgccaagtag caaaaattgg tactgccttt gaagcgacaa accatgaatc
     7561 aacattacaa tacgtattcg gtgaaaagtt tagtaaagtc tttgattata ttttaatctt
     7621 cttcttattt ggtatagctg taaccatgat agctggtgca ggcgcaacat ttgaagaaag
     7681 ttataacata cctacatggc taggtgcatt aattatgaca ttagcaattt atgtaacatt
     7741 gctattagac tttaataaga tagtacgtgc ccttggtgtt gttacaccat ttttaattgt
     7801 tttagttgta ttaatcgctg gcgtttattt atttaaaggt catgtttcat tagcagaagt
     7861 taaccaagta gtgcctgaag caagtatctg gaagggaatc tggtttggta caatatatgg
     7921 tggattagct ttttctgtag gttttagtac catcgtagca atcggtgggg atactgaaaa
     7981 acgtacagtg tcaggtgcag gcgcgatgta tggtggtatt atctatactg tattactagc
     8041 attgatcaac tttgctttac aaagtgaata tcctacaatt aaaaatgcat caattccaac
     8101 attaacatta gccaataaca ttcatccgtt aatagcaacc gtgttatctg ttattatgct
     8161 tgcggttatg tataatacta ttctaggact aatgtattca tttgcagcac gttttacaga
     8221 accatacagt aaaaattatc atatctttat tattataatg atggtagcag gttatttatt
     8281 aagtttcgta ggatttgctg aattaattaa taagttatat acaattatgg gatatgtagg
     8341 cttatttatt gtagtagctg taattattaa atatttcaaa cgtaaaaatg cggataaaaa
     8401 acatattgct taatatcata tgatggatat ccgaaacttt acaattgaat cactttgttt
     8461 taaccttaaa agcaattcgt ctctactctt attgggcgaa ttgcttttta tatttattca
     8521 gtctattaat atgagcgtct aacaaataga gaggtacgat gtaatgaata gagataataa
     8581 atggacgatg ataactgcgc tttttataac tgtaatcagt gtattgttag catttcatct
     8641 gaaacaacat tatgaccaaa ctacaaatga gaaccatgct aataaagaca aaattaatat
     8701 taaaaataaa aatgtgcgca tttatcaaaa tcttacatac aatagagttt tccctaacag
     8761 taaattagat attattacac ctgttgatat gtcttctaat gccaaactgc cagttatttt
     8821 ttggatgcac ggtggtggtt atattgcggg tgataagcag tataaaaacc cattattagc
     8881 gaaaattgct gaacaagggt acattgttgt gaatgtaaat tatgcattgg cgccacaata
     8941 taaatatccc acaccattaa ttcaaatgaa tcaagcaact caattcatta aagaaaataa
     9001 aatgaattta cctattgatt ttaatcaagt agttattggc ggtgattctg ctggcgcaca
     9061 actggctagt caatttacgg caatacagac gaatgatcgc ttaagaaaag ccatgaaatt
     9121 tgatcagtca ttcaaaccat cgcaaattaa aggtgctata ctatttggtg gtttttataa
     9181 tatgcaaaca gttagagaaa ctgagtttcc aagaatacag ttatttatga aaagttatac
     9241 tggcgaagaa gattgggaaa agagttttaa aaacatttca caaatgtcga cagtaaaaca
     9301 atcgacaaaa aattatccac caacattttt atctgttgga gatagcgatc cattcgaaag
     9361 tcaaaatata gaattcagta agaaattaca agaattgaat gtaccagtag atactttgtt
     9421 ttatgatggt acgcatcatt tacatcatca gtatcaattt caccttaata aacctgaatc
     9481 gatagataat atcaaaaaag tgttactgtt cttaagtcgt aatacatctt ctagtggtat
     9541 tcaaactgaa gagaaaccac aaatagaaaa tccgagtaat gaattaccgt taaatccttt
     9601 aaactaataa taaacagtag taatttatta cttaaacaac atttaagacc ttcaaattga
     9661 aaacgaagaa tttaaaacat gtggggctaa tgtgtaagag tctgagatat aataaattgt
     9721 tagcggttct ttatcatttc tatctcactc tattatgatg tgacatttat tttacaaact
     9781 aatttgtttt aaacctgaaa ataacttttt acaactaaat agtc
//
LOCUS       DAPSKH010000078         9792 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPSKH010000078 DAPSKH010000000
VERSION     DAPSKH010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9792)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9792)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9792
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.078"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            236..391
                     /locus_tag="RPH49_002381"
                     /pseudo
     CDS             236..391
                     /locus_tag="RPH49_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499365.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            399..920
                     /locus_tag="RPH49_002382"
     CDS             399..920
                     /locus_tag="RPH49_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125501.1"
                     /translation="MINIISAIGSIGTFIMALFYFVSVSVQLYQMKISFLPALGFNQI
                     LLEREGDQLNIMNSATEEHHHKDYIKLYNLGGGAAKKIAIEVLLGNDKVIQKKYVNIL
                     PSKEGYMLPINKNVYEELERTIENNGYEADLNVRMTYYHNVSRKQQEVILKGQIDRFN
                     TYNNKEIYDLQFI"
     gene            1059..1589
                     /locus_tag="RPH49_002383"
     CDS             1059..1589
                     /locus_tag="RPH49_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDY5125502.1"
                     /translation="MQIRQIHQHDFAQVDQLIRTAFENSEHGYGNESELVDQIRLSDT
                     YDNNLEIVAVLQNEVVGHGLLSEVYLDNGAQREIGLVLAPVSVDIHHQNKGIGKRLIQ
                     ALEREAILKGYNFISVLGWPTYYANLGYQRASMYDIYPPYDGIPDEAFLIKELKVNSL
                     AGKTGTINYTSAFEKI"
     gene            1852..4665
                     /gene="clfA"
                     /locus_tag="RPH49_002384"
     CDS             1852..4665
                     /gene="clfA"
                     /locus_tag="RPH49_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin clumping factor ClfA"
                     /protein_id="HDY5125503.1"
                     /translation="MNMKKKEKHAIRKKSIGVASVLVGTLIGFGLLSSKEADASENSV
                     TQSDSASNESKSNDSSSVSAAPKTVDTNVSDTKTTSNTNSGETSVAQNPAQQETTQSA
                     STNATTEETPATGEATTTATNQANTPATTQSSNTNAEELVNQTNNETTSNDTNTVSSV
                     NSPQNSTNAENVSTTQDTSTEATPSNNESAPQSTDASNKDVVNQAVNTSAPRMRAFSL
                     AAVAADAPAAGTDITNQLTDVKVTIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFK
                     ITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVDNKENVTANIT
                     MPAYIDPENVTKTGNVTLTTGIGTNTASKTVLIDYEKYGQFHNLSIKGTIDQIDKTNN
                     TYRQTIYVNPSGDNVVLPALTGNLIPNTKSNALIDAKNTDIKVYRVDNANDLSESYYV
                     NPSDFEDVTNQVRISFPNANQYKVEFPTDDDQITTPYIVVVNGHIDPASTGDLALRST
                     FYGYDSNFIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPEDSDSDPG
                     SDSGSDSNSDSGSDSGSDSTSDSGSDSASDSDSASDSDSASDSDSASDSDSASDSDSA
                     SDSDSASDSDSASDSDSASDSDSASDSDSASDSDSDSDSDSDSDSDSDSDSDSDSDSD
                     SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD
                     SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSD
                     SDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSESDSDSDSDSDSD
                     SDSDSESDSDSDSGSNNNVVPPNSPKNGTNASNKNEAKDSKEPLPDTGSEDEANTSLI
                     WGLLASLGSLLLFRRKKENKDKK"
     gene            4886..6394
                     /gene="vwb"
                     /locus_tag="RPH49_002385"
     CDS             4886..6394
                     /gene="vwb"
                     /locus_tag="RPH49_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000791704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="von Willebrand factor binding protein Vwb"
                     /protein_id="HDY5125504.1"
                     /translation="MKNKLLVLSLGALCVSQIWESNYASAVVSGEKNPYVSKALSIKG
                     QKTNSWNLGQYKDSLRTVMCTSEINKNDGYDEPEYKEAMDTYRKKLFAELDALNKFLD
                     EERKIESSKKNNNQVANGVLGLTHQRYLAIHEAIKENKNEFERKTQDIESRNPDLKKF
                     DRDKDYEVRVKLNELENKVLMLGHAFPNKHEARENLYNKLDLIVGRSDDEREERHPQN
                     DRLSKERVEDLESIIDEFFVEINENRPLNIPALIESNEENIVMAKKLKADTEEAKANT
                     SKRSKRSLNTQNHKSKINEVTEEQKANYEKKFKEIKERFLAKQKNKNNTPVVSLEYDE
                     DDNENDKKLVVSEPSKKPTTPPTYTETTTQVPMPTVERQTQQQIIYNAPKQLAGLNGE
                     SHDFTTTHQSPTTSNHTHNHLIEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIK
                     REHVREAQKLVDNYKDTHSYKDRLNAQQKVNTLSEGHQKRFNKQINKVYNGK"
     gene            6747..7769
                     /gene="emp"
                     /locus_tag="RPH49_002386"
     CDS             6747..7769
                     /gene="emp"
                     /locus_tag="RPH49_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular matrix protein-binding adhesin
                     Emp"
                     /protein_id="HDY5125505.1"
                     /translation="MKKKLLVLTMSTLFATQIMNSNHAKASVTESVDKKFVVPESGIN
                     KIIPAYDEFKSAPKVNVSNLTDNKNFVVSEGKLNKISDPSAASKIVDKNFVVPESKLG
                     NIVPEYKEINNRVNVATNNPASQQVDKHFVAKGPEVNRFITQNKVNHHFITTQTHYKK
                     VITSYKSTHVHKHVNHAKDSINKHFIVKPSESPRYTHPSQSLIIKHHFAVPGYHAHKF
                     VTPGHASIKINHFCVVPQINSFKVIPPYGHNSHRMHVPSFQNNTTATHQNAKVNKAYD
                     YKYYYSYKVVKGVKKYFSFSQSNGFKTGKPALNIKNVNYQYAVPSYSPTHVVPEFKGI
                     LPAPRV"
     gene            8099..8620
                     /locus_tag="RPH49_002387"
     CDS             8099..8620
                     /locus_tag="RPH49_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001627793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125506.1"
                     /translation="MKRKVLVLTMGVLCATQLWHSNHANALVTESVETNFVVKDSGNN
                     NILQTHTEITTEEKFSIVEKSQLNTLKSLSNDNYIEYDLHTNQTGIKKGWLYGYSEID
                     SSHFTDCDKRAIRRDHVKEAQSLINDYKDTQSYEDLAKATAKVSTLSQSHQNYLNKQI
                     DKVNNKIEKTEKR"
     gene            8961..9647
                     /locus_tag="RPH49_002388"
     CDS             8961..9647
                     /locus_tag="RPH49_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDY5125507.1"
                     /translation="MTEYLLSAGICMAIVSILLIGMAISNVSKGQYAKRFFFFATSCL
                     VLTLVVVSSLSSSANASQTDNGVNRIGSEDSTVYSATSTKKLHKEPATLIKAIDGDTV
                     KLMYKGQPMTFRLLLVDTPETKHPKKGVEKYGPEASAFTKKMVENAKKIEVEFDKGQR
                     TDKYGRGLAYIYADGKMVNEALVRQGLAKVAYVYKPNNTHEQLLRKSEAQAKKEKLNI
                     WSEDNADSGQ"
BASE COUNT         3801 a         1424 c         1729 g         2838 t
ORIGIN      
        1 atatattact tttttaaaaa acttgtaata tatcgaaaga tttaaatgta aaattttgat
       61 ttgttaagaa attgcgttta taaaaataaa aaaatcaact tatttgtatg agatgaatat
      121 gtattgaaga agacgtgtta ttaatttgga aaatactggt caaagatgga agctctcaaa
      181 agcgttattg tattctttag tcaatgcaaa tagattgccg taataataat cgtacttgat
      241 ggttaaaaaa ttacttaagg ctttaaagca aaacttttta tatgagtagt cgaatataac
      301 gtttaaaatg attgtttttg gatataaacg attaagtaaa atgctttttc agtttgtaat
      361 taatcatata aatttcttat gggaaggttg atatcttaat gattaatatt atttcagcta
      421 taggatctat tgggacattt attatggctt tattttattt tgtatcagtt tcagttcaac
      481 tttatcaaat gaaaattagc tttctgccag ctttaggttt taaccaaatt ttattagaaa
      541 gggagggtga tcaacttaat ataatgaatt cggcaacaga agagcatcat cataaagatt
      601 atattaaact atataattta ggtggcggtg ctgctaaaaa aattgcaata gaggttttat
      661 tgggtaatga taaagtcatt cagaaaaaat acgtgaatat tttacctagt aaagaagggt
      721 acatgttacc aattaataaa aatgtgtacg aagaattaga aagaacgatt gagaacaatg
      781 gttatgaagc tgatttgaat gtacgtatga cttattatca taatgtaagt cgcaaacaac
      841 aggaagttat attaaaaggt caaatcgacc gttttaatac ttataataat aaagaaattt
      901 atgatttgca gtttatctaa aaattgattt aagagggtag ttgtttattg cgaaaaatat
      961 cattcaattt taatgaaata atggcgtcat tactataaaa tattacttta tgttgtaaag
     1021 catttttcta taagatagaa ctaaaaggag gggcaaagat gcaaattaga caaatacatc
     1081 aacatgactt tgctcaagtt gaccagttaa ttagaacggc atttgaaaat agtgaacatg
     1141 gttatggtaa tgaatcagag ctagtagacc aaattcgtct aagtgatacg tatgacaata
     1201 acttagaaat agtagctgtt cttcaaaacg aagttgtagg gcacggttta ctaagtgaag
     1261 tttatcttga taacggagca caacgggaaa ttggattagt gttagcacct gtatctgttg
     1321 atattcatca tcaaaataaa ggtataggga agcgattgat tcaagcatta gaacgagaag
     1381 caatattaaa aggatataat tttatcagtg tattaggatg gccgacgtat tatgccaatc
     1441 taggatatca acgcgcaagt atgtacgaca tttatccacc atatgatggt ataccagacg
     1501 aagcgttttt aattaaagaa ttaaaagtga acagtttagc gggaaaaaca ggtaccataa
     1561 attacacatc tgcttttgaa aaaatatgat ttcaagatag gattacatta ggcagagttc
     1621 atattaataa tacaaattgt tcgcaatgaa atcgcacgtt gtcgtttgca atttataaaa
     1681 tagcaataaa taaaatgttt gttaggaaag tattattgtg gataataaaa aatcgataca
     1741 aattaattgc tataatgcaa ttttagtgta taattgcatt aatggagatt aaatatatct
     1801 ttaaagggta tacagttaat ataaaatgac tttttaaaaa gagggaataa aatgaatatg
     1861 aagaaaaaag aaaaacacgc aattcggaaa aaatcgattg gcgtggcttc agtgcttgta
     1921 ggtacgttaa tcggttttgg actactcagc agtaaagaag cagatgcaag tgaaaatagt
     1981 gttacgcaat ccgatagcgc aagtaacgaa agcaaaagta atgattcaag tagcgttagt
     2041 gctgcaccta aaacagtcga cacaaacgtg agtgatacta aaacaacgtc aaacactaat
     2101 agtggcgaaa caagtgtggc gcaaaatccg gcacaacagg aaacgacaca atcagcatca
     2161 acaaatgcaa ctacggaaga aactccggca actggtgaag ctactactac ggcaacgaat
     2221 caagctaata caccggcaac aactcaatca agcaatacaa atgcggagga attagtgaat
     2281 caaacaaata atgaaacgac ttctaatgat actaatacag tatcatctgt aaattcacct
     2341 caaaattcta caaatgcgga aaatgtttca acaacgcaag atacttcaac tgaagcaaca
     2401 ccttcaaaca atgaatcagc tccacagagt acagatgcaa gtaataaaga tgtagttaat
     2461 caagcggtta atacaagtgc gcctagaatg agagcattta gtttagcggc agtagctgca
     2521 gatgcaccgg ctgctggcac agatattacg aatcagttga cagatgtgaa agttactatt
     2581 gactctggta cgactgtgta tccgcaccaa gcaggttatg tcaaactgaa ttatggtttt
     2641 tcagtcccta attctgctgt taaaggtgac acattcaaaa taactgtacc taaagaatta
     2701 aacttaaatg gtgtaacttc aactgctaag gtgccaccaa ttatggccgg agatcaagta
     2761 ttggcaaatg gtgtaatcga tagtgatggt aatgttattt atacatttac agactatgtt
     2821 gataataaag aaaatgtaac agctaatatt actatgccag cttatattga ccctgaaaat
     2881 gttacaaaga caggtaatgt gacattgaca actggcatag gaaccaatac tgctagtaag
     2941 acagtattaa tcgactatga gaaatatgga caattccata atttatcaat taaaggtacg
     3001 attgatcaaa tcgataaaac aaataatacg tatcgccaaa caatttatgt caatccaagc
     3061 ggagataacg ttgtgttacc tgccttaaca ggtaatttaa ttcctaatac aaagagtaat
     3121 gcgttaatag atgcaaaaaa cactgatatt aaagtttata gagtcgataa tgctaatgat
     3181 ttatctgaaa gttattatgt gaatcctagc gattttgaag atgtaactaa tcaagttaga
     3241 atttcatttc caaatgctaa tcaatacaaa gtagaatttc ctacggacga tgaccaaatt
     3301 acaacaccgt atattgtagt tgttaatggc catattgatc ctgctagtac aggtgattta
     3361 gcactacgtt cgacatttta tggttatgat tctaatttta tatggagatc tatgtcatgg
     3421 gacaacgaag tagcatttaa taacggatca ggctctggtg acggtatcga taaaccagtt
     3481 gttcctgaac aacctgatga gcctggtgaa attgaaccaa ttccagagga ttcagattct
     3541 gacccaggtt cagattctgg cagcgattct aattcagata gcggttcaga ttcgggtagt
     3601 gattctacat cagatagtgg ttcagattca gcaagcgatt cagattcagc aagtgattca
     3661 gattcagcaa gtgattcaga ctcagcaagt gattcagatt cagcaagtga ttcagattca
     3721 gcaagtgatt cagactcagc aagtgattca gattcagcaa gtgattcaga ctcagcaagt
     3781 gattcagatt cagcgagcga ttcagattca gcgagtgatt cagattcaga cagcgattca
     3841 gactcagaca gtgactcaga ttccgatagt gactcagact cagatagcga ctcagattcc
     3901 gatagtgact ccgactcaga cagcgattca gattcagata gtgattcaga ttcagatagc
     3961 gattcggatt cagatagtga ctcagattca gatagcgact cagattcaga tagcgattca
     4021 gattccgaca gtgactcaga ttccgacagc gattcagatt ccgacagtga ctcagactca
     4081 gacagtgatt cggattcaga tagcgattca gactcagaca gtgactcgga ttcagatagc
     4141 gattcagact cagacagtga ctcggattca gatagcgatt ccgactcaga cagtgattca
     4201 gactcagaca gcgattcaga ttccgacagt gactccgact cagacagcga ttccgactca
     4261 gacagtgact cggattcaga tagcgattct gactcagata gtgactccga ctcagacagc
     4321 gactcagatt cagatagcga ttcagattcc gacagtgact cagattcgga tagcgattca
     4381 gaatcagata gtgactccga ctcagacagc gactcagatt cagatagcga ttcagaatca
     4441 gatagtgact ccgactcagg ttctaacaat aatgtagtgc cgcctaattc acctaaaaat
     4501 ggtactaatg cttctaataa aaatgaggct aaagatagta aagagccatt accagataca
     4561 ggttctgaag atgaagcgaa tacgtcacta atttggggat tattagcatc attaggttca
     4621 ttactacttt tcagaagaaa aaaagaaaat aaagataaga aataagtaat aatgatatta
     4681 aattaataat atgattcatg aagaagccac cttaaaaggt ggctttttta cttggatttt
     4741 ccaaatatat tgtttgaata taattaataa ttaattcatc aacagttaat tattttaaaa
     4801 aggtagatgt tatataattt ggcttggcga aaaaataggg tgtaaggtag gttgttaatt
     4861 agggaaaatt aaggagaaaa tacagttgaa aaataaattg ctagttttat cattgggagc
     4921 attatgtgta tcacaaattt gggaaagtaa ttatgcgagt gcagtggttt ctggggagaa
     4981 gaatccatat gtatcaaaag ctttatcaat taaaggtcaa aagacaaatt catggaattt
     5041 aggtcaatat aaagatagtc ttcgaacagt tatgtgcaca tcagaaatta ataaaaatga
     5101 tggatatgat gaacctgaat ataaagaggc gatggatact taccgaaaaa aattatttgc
     5161 tgaattagat gcgcttaaca agtttttaga tgaagagaga aaaatagaaa gtagtaaaaa
     5221 aaataacaac caagttgcaa atggtgtatt gggcttaaca catcaaaggt atttagctat
     5281 tcatgaagca ataaaggaaa ataaaaatga gtttgaaaga aagacacaag atatcgaaag
     5341 tagaaatcct gatttgaaaa aatttgatag agataaagat tacgaagtta gagtaaaatt
     5401 aaatgaacta gaaaataaag tattaatgct tggacacgct tttccaaata aacatgaagc
     5461 aagagagaat ctttataata aattagattt gattgttggc cgtagtgatg atgagagaga
     5521 agaaaggcat cctcaaaatg ataggttatc taaagaacga gttgaagatt tagaatcaat
     5581 tattgatgaa ttttttgttg aaatcaatga aaataggccg ttgaatatac cggcgttaat
     5641 tgaaagtaat gaagaaaata tagtaatggc aaaaaaacta aaagcagata cagaagaagc
     5701 taaagcgaat acatctaaaa gaagtaaaag aagtttaaat actcaaaatc acaaatctaa
     5761 aataaacgaa gtaactgaag aacaaaaagc taattatgaa aagaaattta aagaaataaa
     5821 agaacgattt ttagctaaac aaaaaaataa aaataacaca ccagttgtat cgttagaata
     5881 tgacgaagac gacaacgaaa acgacaagaa acttgtggtt tctgagccat caaagaaacc
     5941 aacaacaccg cctacatata ctgaaacaac gacacaggta cctatgccta cagttgagcg
     6001 tcaaactcag caacaaatta tttataatgc accaaaacaa ttggctggat taaatggtga
     6061 aagtcatgat ttcacaacaa cgcatcaatc accaacaact tcaaatcata cgcataatca
     6121 tcttattgaa tttgaagaaa cgtctgcttt acctggtaga aaatcaggat cactggttgg
     6181 tataagtcaa attgattctt ctcatctaac tgaacgtgag aagcgtgtaa ttaagcgtga
     6241 acacgttaga gaagctcaaa agttagttga taattataaa gatacacata gttataaaga
     6301 ccgattaaat gcacaacaaa aagtaaatac tttaagtgaa ggtcatcaaa aacgttttaa
     6361 taaacaaatc aataaagtat acaatggcaa ataatattaa tgcatggctg caaagcaaat
     6421 aatgagtttg tcgtaaaaat cacaacattt taaactagca ataaataata tcaaagtcat
     6481 caattcaatg atgcaatcta gtatagtcca cattctaaac aggtgtggac tattactttt
     6541 ttcactttat attacgaaaa aattattatg cttaactatc aatatcaata attaatttta
     6601 agctgaaaaa caataaaaat gttaagacaa cgtttacttc aagttaatta ttatactgaa
     6661 aattctggta tataatgctg ttagtgaata taacaggaaa attaaattgg ttataatatt
     6721 gagtctatat aaaggagaaa taacagatga aaaagaaatt attagtttta actatgagca
     6781 cgctatttgc tacacaaatt atgaattcaa atcacgctaa agcatcagtg acagagagtg
     6841 ttgacaaaaa atttgtagtt ccagaatcag gtattaataa aattattcca gcttacgatg
     6901 aatttaagag tgcaccaaaa gtaaatgtta gtaatttaac tgacaataaa aattttgtag
     6961 tttctgaagg caaattgaat aagatttcag atccttcagc agcaagtaaa attgtagata
     7021 aaaactttgt cgtaccagaa tcaaagttag gaaacattgt gccagagtac aaagaaatca
     7081 ataatcgcgt gaatgtagca acaaacaatc cagcttcaca acaagttgat aagcattttg
     7141 ttgctaaagg cccagaagta aatagattta ttacgcaaaa caaagtaaac caccacttca
     7201 ttactacgca aacccactac aagaaagtta ttacttcata caaatcaaca catgtacata
     7261 aacatgtaaa tcatgcaaag gattctatta ataaacactt tattgttaaa ccatcagaat
     7321 cgcctagata tacacatcca tctcaatctt taattatcaa gcatcatttt gcagttcctg
     7381 gatatcacgc gcataaattt gttacaccag ggcatgctag cattaaaatt aatcactttt
     7441 gtgttgtgcc acaaataaat agtttcaagg taattccacc atatggtcac aattctcacc
     7501 gtatgcatgt accaagtttc caaaataaca caacagcaac acatcaaaat gctaaagtaa
     7561 ataaagcata tgactataaa tactactatt cttataaagt agttaaaggt gtgaaaaaat
     7621 atttctcatt ttcacaatct aatggtttta aaactggtaa accagcatta aatatcaaaa
     7681 atgtaaatta tcaatatgct gttccaagtt atagccctac acacgttgtt cctgaattta
     7741 agggcatttt accagcacca cgagtataaa aattggcact aagtttacga gatatgataa
     7801 atacctatta ttttaaatat agtctgcaat ctatgaggtt gtaggctatg ttttttgcaa
     7861 tttagcaatc aacacccatc aacaaattat accgtttttc tactttcaaa gttggaagta
     7921 acataatctt aaataaatat attattaatt aagataaata taagactcaa gattattgtt
     7981 aatagtttgt tcatcgcaag ttaattatta tttctaaaaa attggtatat aatttcgatg
     8041 gcgaagaaaa cagggtgaaa aagtcggttt tacaatcaat gcaaataagg agtaaaaaat
     8101 gaaaaggaaa gtactagtat taacaatggg cgtactttgt gcgacgcaat tatggcattc
     8161 taatcacgca aacgcattag tgacagagag tgttgaaact aattttgttg taaaagattc
     8221 gggtaataat aatattttac aaacccatac tgaaattact actgaggaga aattttcaat
     8281 agtagaaaag agccaattaa atacactaaa atcactatct aatgacaact acatagaata
     8341 tgatttacat actaatcaaa caggcattaa aaaaggttgg ttatatggct atagtgaaat
     8401 tgactcatca catttcacag actgtgacaa acgcgctatt agacgtgatc atgttaaaga
     8461 agcacaaagc ttaattaacg attataaaga tacacaaagt tatgaagatc tcgctaaggc
     8521 aactgcaaaa gtaagtacac ttagtcagtc tcatcaaaat tatttgaata aacaaattga
     8581 taaagtgaat aataagatag agaaaactga aaaacgctaa tccaaagtaa attataagtt
     8641 atacatctcg tttttaaatg acaatttatc cccgtaaata ttataaataa tcttttcaaa
     8701 ttccacatag atatagagac actaataaac ctctttgtct cgatatgata gtctgcaacg
     8761 attcatgttg taggcttttt aattttacaa ataaggctaa atatataagt tctgacacct
     8821 aaaatataga aaatacataa aagtaagtat agttatttta ttataattat taaattttta
     8881 ttaattaatt gtaaaaatgt agaattataa ttaattaacg tttaatatta aaattaacta
     8941 aaaagaaaga ggtgttagtt atgacagaat acttattaag tgctggcata tgtatggcaa
     9001 ttgtttcaat attacttata gggatggcta tcagtaatgt ttcgaaaggg caatacgcaa
     9061 agaggttttt ctttttcgct actagttgct tagtgttaac tttagttgta gtttcaagtc
     9121 taagtagctc agcaaatgca tcacaaacag ataacggcgt aaatagaatt ggttctgaag
     9181 attcaacagt atatagtgca acttcaacta aaaaattaca taaagaacct gcgacattaa
     9241 ttaaagcgat tgatggtgat acggttaaat taatgtacaa aggtcaacca atgacattca
     9301 gactattatt agttgataca cctgaaacaa agcatcctaa aaaaggtgta gagaaatatg
     9361 gccctgaagc aagtgcattt acgaaaaaaa tggtagaaaa tgcaaagaaa attgaagtcg
     9421 agtttgacaa aggtcaaaga actgataaat atggacgtgg cttagcgtat atttatgctg
     9481 atggaaaaat ggtaaacgaa gctttagttc gtcaaggctt ggctaaagtt gcttatgttt
     9541 ataaacctaa caatacacat gaacaacttt taagaaaaag tgaagcacaa gcgaaaaaag
     9601 agaaattaaa tatttggagc gaagacaacg ctgattcagg tcaataatgc tcattgtaaa
     9661 agtgtcactg ctgctagtgg cacttttata atttttagat cacgatatga tttattatca
     9721 attcagaatt aaaaaagtaa atagtatcaa aagcaagtgt atttaatatt agaaaataaa
     9781 aattttaaat tt
//
LOCUS       DAPSKH010000079         9736 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPSKH010000079 DAPSKH010000000
VERSION     DAPSKH010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9736)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9736)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9736
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.079"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(90..794)
                     /locus_tag="RPH49_002389"
     CDS             complement(90..794)
                     /locus_tag="RPH49_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="queuosine precursor transporter"
                     /protein_id="HDY5125508.1"
                     /translation="MYNEILGLVTFIATFVLMVLMYRFFGKQGLIAWVAIGTIIANIQ
                     VIKTVEIFGISATLGNVMFASIYLATDILNDIYGRRVAKRAVWLGFSSTLIMIIVMQL
                     SLHFIPAPEDMAQKALHAIFDVVPRIALGSIVAYIIGQHIDVFIFSLIKKVFSSDKTF
                     FIRAYGSTFLSSIIDTALFVAIAFIGSLPGTVVFEIFITTYVLKLASTVFNVPFGYIA
                     KSFYRKGKIDKLDQGY"
     gene            1039..1233
                     /locus_tag="RPH49_002390"
     CDS             1039..1233
                     /locus_tag="RPH49_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002439757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-finger domain-containing protein"
                     /protein_id="HDY5125509.1"
                     /translation="MSRILTFSEQNALAKIDDLMNTYCNQCPIKTRLRKLEGKTKSHH
                     FCINECSIGKEIKQLGNELQ"
     gene            1245..1496
                     /locus_tag="RPH49_002391"
     CDS             1245..1496
                     /locus_tag="RPH49_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NifU N-terminal domain-containing protein"
                     /protein_id="HDY5125510.1"
                     /translation="MQIISISETPNHNTMKITLSESREGMTSDTYTKVDDSQPAFIND
                     ILKVEGVKSIFHVMDFISVDKENDANWETVLPKVEAVFE"
     gene            1534..2658
                     /locus_tag="RPH49_002392"
     CDS             1534..2658
                     /locus_tag="RPH49_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor"
                     /protein_id="HDY5125511.1"
                     /translation="MEILRIEPTPSPNTMKVVLSYTREDKLSNTYKKVEENQPRFINQ
                     LLSIDGITSIFHVMNFLAVDKAPKADWEVILPDIKAAFSGESQVLESGKDPQIDKHFG
                     EIKAELLTFKGIPYQIKLTSADQELREQLPQTYVDHMTQAQTEHDNIVFMRKWLDLGN
                     RYGNIEEVMDGVLEEVLATYPESQLPVLVKHALEENHAANNYHFYRHVSLDEYHATDN
                     WKTRLRMLNHFPKPTFEDIPLLDLALSDEKVPVRRQAIVLLGMIESKEILPYLYKGLR
                     DKSPAVRRTAGDCISDLGYPEALPEMVLLLDDSQKIVRWRAAMFIFDEGNAEQLPALK
                     AHINDNAFEVKLQIEMAISRIENGDEALGSVWKQMANRTI"
     gene            2674..3111
                     /locus_tag="RPH49_002393"
     CDS             2674..3111
                     /locus_tag="RPH49_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA/BrxB family bacilliredoxin"
                     /protein_id="HDY5125512.1"
                     /translation="MNAYDAYMKEIAQQMRGELTQNGFTSLETSEAVLEYMNQVNADD
                     TTFVVINSTCGCAAGLARPAAVAVATQNEHRPTNTVTVFAGQDKEATATMREFIQQVP
                     SSPSYALFKGQDLVYFMPREFIEGRDINDIAMDLKDAFDENCK"
     gene            3535..4491
                     /locus_tag="RPH49_002394"
     CDS             3535..4491
                     /locus_tag="RPH49_002394"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDY5125513.1"
                     /translation="MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGAISKFGHQLRFDLS
                     KGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYKGP
                     DMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKD
                     GNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQL
                     YQRSADIFLGVPYNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLA
                     RESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV"
     gene            4691..5170
                     /locus_tag="RPH49_002395"
     CDS             4691..5170
                     /locus_tag="RPH49_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDY5125514.1"
                     /translation="MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMG
                     RKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEM
                     IDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVTSSVEGKLDEKNTIPHTFLHLIRKK"
     gene            5185..6024
                     /gene="fakB2"
                     /locus_tag="RPH49_002396"
     CDS             5185..6024
                     /gene="fakB2"
                     /locus_tag="RPH49_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase binding subunit FakB2"
                     /protein_id="HDY5125515.1"
                     /translation="MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGVSYVDQVDI
                     TSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQA
                     SQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIG
                     QLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEF
                     IGDHEIKSVGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVV
                     LKK"
     gene            6110..6643
                     /gene="msrA"
                     /locus_tag="RPH49_002397"
     CDS             6110..6643
                     /gene="msrA"
                     /locus_tag="RPH49_002397"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDY5125516.1"
                     /translation="MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYE
                     QVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYH
                     DEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQR
                     GSGRKAFIESHWGNQNA"
     gene            6636..7064
                     /gene="msrB"
                     /locus_tag="RPH49_002398"
     CDS             6636..7064
                     /gene="msrB"
                     /locus_tag="RPH49_002398"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDY5125517.1"
                     /translation="MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKIS
                     GKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFN
                     DGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK"
     gene            7076..7576
                     /locus_tag="RPH49_002399"
     CDS             7076..7576
                     /locus_tag="RPH49_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDY5125518.1"
                     /translation="MFKKLFGKGKEVQKDIAIYAPLTGEYVKIEDIPDPVFAQKMMGE
                     GFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVL
                     VSSGDEVNVGDPLVRFNLEFINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKV
                     IDVTMN"
     gene            7576..7797
                     /locus_tag="RPH49_002400"
     CDS             7576..7797
                     /locus_tag="RPH49_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDY5125519.1"
                     /translation="MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILS
                     DYIETHGDFTLPMSVFDDLYEEYTEWLKF"
     gene            7986..9476
                     /locus_tag="RPH49_002401"
     CDS             7986..9476
                     /locus_tag="RPH49_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDY5125520.1"
                     /translation="MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILI
                     GTILITAVITVVAYIFINQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKA
                     AIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
                     ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREK
                     IHVKSVEYKKKDKVGVITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLD
                     EAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDISILVNEGSASASEVF
                     TGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPD
                     VTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQV
                     KAFQQTNKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK"
BASE COUNT         3622 a         1405 c         1726 g         2983 t
ORIGIN      
        1 ttgccggggt gggacgacga aataaatttt gcgaaaatat catttctgtc ccactccctt
       61 aaaacttatt ctattatgta gtaagtgcgt taataacctt gatctaattt atcaatcttg
      121 cctttacgat aaaatgattt agcaatatat ccaaatggta cattgaaaac tgttgaagct
      181 aattttagta cgtacgttgt aataaatatt tcaaatacaa ctgtaccagg taaacttccg
      241 ataaatgcga tagctacaaa taaagctgta tcaattattg agcttaaaaa tgtactacca
      301 tatgcacgga tgaaaaacgt tttatcagaa ctaaatactt ttttaattag tgaaaagata
      361 aatacatcaa tatgttgacc aataatatat gcgacgattg agcctaaagc aatgcgtggc
      421 acaacatcaa agattgcgtg taaagctttt tgtgccatat cttctggtgc aggaataaaa
      481 tgtaatgaca attgcataac aataatcata attaatgttg atgaaaagcc taaccaaact
      541 gctctttttg caactctacg cccataaata tcgtttaata tatctgttgc taaataaata
      601 gaagcaaaca tgacattacc taaagttgct gaaataccaa agatttctac agttttaatt
      661 acttgtatgt tggcaatgat tgtgccaatt gcaacccatg caattaaacc ttgtttacca
      721 aaaaagcgat acataagtac cataagcacg aacgttgcaa taaacgtaac tagtcctaaa
      781 atttcattat acatattaaa atgtcctcct aaattttgat catgcgggtg tttagaaacc
      841 gctcaataaa taacttactc attttactga aaaatcgttt gcgatgcaat agcatttgaa
      901 tataaataca ttttacgtat agaattgtaa aaggtttcat tcaaatctta gggtcaaaaa
      961 tgttataata tttttatgtc aaatttaaag cagtaacact tatttacaag gttgcaatat
     1021 tttgaagtaa taaaggaagt gtcgcgtatt ttaacttttt cagagcaaaa tgcactcgcg
     1081 aaaatagatg atttaatgaa tacttattgc aatcaatgtc caatcaaaac tcgtctgcgt
     1141 aaattagagg ggaaaacgaa gtcgcatcat ttttgtatca atgagtgttc aatagggaaa
     1201 gaaataaaac aattaggaaa tgaacttcaa taggaggaag taaaatgcaa attatatcta
     1261 tatcagaaac accgaaccac aacacaatga agattacact tagtgaaagc agagaaggta
     1321 tgacatcaga tacgtatact aaagttgatg attcacagcc agcatttatt aatgacatct
     1381 taaaggttga aggcgttaaa tcaattttcc atgttatgga ctttatttca gtagataaag
     1441 aaaatgacgc aaattgggaa acagtattgc caaaagtaga ggctgtattc gaataaattt
     1501 ttcatcaact agtattcggg gggaataaag tatatggaaa ttttacgtat agagccaacg
     1561 ccaagtccaa atacaatgaa agttgttttg tcatatacaa gagaagacaa gttatctaat
     1621 acttataaaa aagtagaaga aaatcaacca agatttataa atcagttgtt atctatagat
     1681 ggtatcactt ccatttttca tgtcatgaac ttcttagctg ttgataaggc accaaaagct
     1741 gattgggaag tcatattacc tgatattaaa gctgcttttt ctggtgaaag tcaggtattg
     1801 gaatctggaa aagacccaca aattgataaa cattttggtg aaattaaagc tgaattatta
     1861 acttttaagg gtataccgta tcaaattaag ctaacttctg ctgaccagga attaagagaa
     1921 caattaccac aaacatacgt tgatcatatg actcaagcgc aaacagaaca tgacaatatt
     1981 gtttttatgc gtaaatggct agatttagga aatcgctatg gaaatattga agaagtaatg
     2041 gatggtgtcc tagaagaagt gttagctacc tatccagaat cacagttgcc cgtattggta
     2101 aaacatgctt tagaagaaaa tcacgcagct aataattatc atttctatcg acatgtctct
     2161 ttggatgaat atcatgcgac tgataattgg aagactcgat tgcgaatgtt aaaccatttt
     2221 ccaaagccga cttttgaaga tataccgctg cttgatttag ctttatctga tgaaaaagta
     2281 ccggttagac gtcaagcgat tgtattatta ggcatgattg aaagtaaaga aattttaccg
     2341 tatttatata agggacttcg cgataaaagt cctgctgtaa gaaggacagc aggggattgc
     2401 ataagtgatt tagggtatcc agaggcacta ccagaaatgg tgctactttt agatgattca
     2461 cagaagatcg ttaggtggcg tgctgctatg tttatctttg atgaaggtaa tgcagagcag
     2521 cttcccgcac ttaaagccca tattaatgac aatgcgtttg aagttaaatt acaaattgaa
     2581 atggccatat ctcgtattga aaacggagat gaagcacttg gttcagtatg gaaacaaatg
     2641 gcaaacagaa caatttaatt ggaggaatta aatatgaatg catatgatgc ttatatgaaa
     2701 gaaattgcgc aacaaatgcg tggcgaatta actcaaaatg gttttacaag tttagaaacg
     2761 agcgaagcag tattagagta tatgaaccaa gtaaatgctg atgacacaac ttttgtagtt
     2821 attaactcta catgcggctg tgcagctgga ttagcaagac cagctgcagt agctgttgca
     2881 acacaaaatg aacatagacc aacaaataca gttacagttt ttgcagggca agataaagaa
     2941 gcaactgcta ctatgcgaga attcattcag caggtaccat ctagtccttc gtatgcttta
     3001 ttcaaaggtc aagatttagt ttattttatg cctagagaat ttatcgaagg tagagatatt
     3061 aatgacattg caatggactt aaaggatgcc tttgacgaaa attgtaaata gtacacataa
     3121 ataaatataa aggttaacac attctataat attaaaaatg gtgtctgtca ttgaaaatag
     3181 agaatttagt tgtattctat ttgttatata aagtccgtac acttcaacta tattttctat
     3241 aaatttaact gttttaatag gacatcaaac ataatattca aatcatgtgt taacctcttt
     3301 tttaaaattt tttagcatta aagttataga tttgggtaaa caattagcaa ttggaaacat
     3361 ttatcacttt acgatgtggt aggtacttaa tcagcatttt ataaattaag taacggaatc
     3421 catgatatta atatcacatt cctaaaatga gtgataacaa aatgctacat aaagttaaat
     3481 tatatcaaac taaatataca tactataaat aatgaaaatg aggtgttatc gcatatgttg
     3541 aattcatttg atgcagcata tcacagtctt tgtgaagaag ttttagaaat aggaaataca
     3601 cgaaatgatc gcacaaatac aggtgcgatt tcgaaatttg gtcatcaact tcgctttgac
     3661 ttatctaaag gatttccact attaacgaca aagaaagttt cttttaaatt agtagcaacc
     3721 gaattattat ggttcattaa aggagataca aacatccaat acttattaaa atataataat
     3781 aatatttgga acgaatgggc ttttgaaaat tatattaaat cagacgagta taaaggtcca
     3841 gatatgacag atttcggaca tcgtgcattg agtgatcctg aatttaacga acaatataaa
     3901 gaacaaatga aacaatttaa gcaacgtatt cttgaagatg atacatttgc gaagcaattc
     3961 ggtgatttag gaaatgttta tggtaaacaa tggcgagatt gggttgataa agatggtaat
     4021 cattttgatc aacttaaaac agtaattgaa caaattaagc ataatccaga ttcaagacga
     4081 cacatcgtat ctgcatggaa tccaacagaa attgatacaa tggcacttcc gccttgtcat
     4141 acaatgttcc agttttatgt ccaagatggt aagttaagtt gccagttata ccaacgtagc
     4201 gcagatatct ttttaggtgt gccatataat atcgcaagct acgctttatt gacacacctt
     4261 attgccaaag aatgtggact tgaagtaggt gaatttgtgc atacatttgg agatgcacat
     4321 atttattcaa atcatattga tgcaattcaa actcaattag cgcgtgaaag tttcaatcct
     4381 ccaacattaa aaattaacag tgacaagtct attttcgaca taaattatga agatttggaa
     4441 attgttgact atgaatcgca tccagcaata aaagctccaa tagcagtgta gtcattgcat
     4501 agttagctaa ccatatagac atcaaaatga catcatagta ttttcaagtg caaaaaagta
     4561 cttttttgtg ttaaacgttt tcataaatta tgcaaaatca ttatttctat cacactttat
     4621 gataaaaatt gtgttaaatt aaagataact tagtaataaa aaatgaaatg atagaagaag
     4681 gaggataatt atgactttat ccattctagt tgcacatgac ttgcaacgag taattggttt
     4741 tgaaaatcaa ttaccttggc acctaccaaa tgatttgaag catgttaaaa aactatcaac
     4801 aggtcatact ttagtaatgg gtcgtaagac atttgaatcg attggtaaac cactaccgaa
     4861 tcgtcgaaat gttgtactta cttcagatac aagtttcaac gtagagggcg ttgatgtgat
     4921 tcattctatt gaagatattt accaactacc gggacatgtt ttcatatttg gagggcaaac
     4981 attatttgaa gaaatgattg ataaagtgga cgacatgtat attactgtta ttgaaggtaa
     5041 attccgtggt gatacgttct tcccacctta tacatttgaa gactgggaag ttacctcttc
     5101 agttgaaggt aaactagatg agaaaaatac aattccacat acctttctac atttaattcg
     5161 taaaaaataa gggggaaaac gaccatgaca aaacagatta tagtaacaga ctcaacatcc
     5221 gatttatcta aagaatattt agaagcaaac aacattcatg taattccttt aagtttaact
     5281 attgaaggag tttcatacgt tgaccaagta gatattacat cagaagaatt tattaatcat
     5341 attgaaaatg atgaagatgt aaagacaagt cagccagcca taggtgaatt tatatctgct
     5401 tatgaagaac taggaaaaga tggctccgaa atcataagta ttcatctttc ttcaggatta
     5461 agtggtacat ataacactgc ttaccaagca agtcaaatgg tagatgctaa tgtaactgtt
     5521 attgattcaa aatctatttc ttttggttta gggtatcaaa tacaacacct agtagagctt
     5581 gtaaaagaag gtgtctcaac ttctgaaata gttaaaaagt taaatcattt aagagaaaac
     5641 attaaattat ttgtagttat agggcaattg aatcaattaa ttaaaggtgg cagaattagt
     5701 aaaacaaaag gtttgattgg taatcttatg aaaatcaaac caattggtac actagatgat
     5761 ggtcgcttag agcttgtgca caatgcgaga actcaaaatt ctagtatcca atacttgaaa
     5821 aaggaaattg ctgaatttat aggagatcat gaaatcaaat ccgttggtgt cgcacatgct
     5881 aacgttattg aatatgttga taaattgaag aaagttttta atgaagcttt tcatgtgaat
     5941 aattacgata taaatgtaac tacaccagtt atttctgcac atactggtca aggtgcgatt
     6001 ggcctcgtag tccttaagaa gtaaatttaa tcttttcagt gttaattact tccatttcaa
     6061 tcctttatag actaaattta taattagata gatagaggag gtaattcata tgacaaaaga
     6121 atatgcaaca ttagcaggag gatgtttctg gtgcatggtt aaaccattta catcatatcc
     6181 aggcatcaag tcagtcgtat ctggttatag tggcggtcat gttgacaacc caacttatga
     6241 acaggtatgt acgaatcaaa ccggccatgt cgaagcagta caaattacgt ttgatccaga
     6301 ggttacttcc tttgaaaata tattagacat atatttcaaa acatttgacc caaccgatga
     6361 tcaagggcaa tttttcgata gaggcgaaag ctatcaacca gtcattttct atcatgatga
     6421 gcatcagaaa aaggctgctg agtttaaaaa gcaacaatta aatgaacaag gtattttcaa
     6481 gaaaccagtg attacaccta ttaaaccata taaaaatttc tatccagctg aagactacca
     6541 tcaagattat tacaaaaaga acccggtaca ttattaccaa tatcaacgtg gttcaggtag
     6601 aaaagcgttt atagaatcac attgggggaa tcaaaatgct taaaaaagat aaaagcgaac
     6661 taacagatat agaatatatt gttacacaag aaaatggtac tgaaccacca tttatgaatg
     6721 aatattggaa tcattttgct aaagggattt acgtagataa gatttctggt aaacctttat
     6781 ttacatctga agaaaagttt cattctgagt gcggatggcc tagcttttcc aaagcgcttg
     6841 atgacgatga aattatagaa ttagtcgaca aatcatttgg tatggtaaga actgaagtcc
     6901 gttcagaaga atcaaatagt catttaggac acgtctttaa tgatggacct aaagaaagtg
     6961 gcggcttaag atactgtatc aattccgctg caattcaatt tattccatat gaaaaattag
     7021 aagaattggg ttatggcgat ttaatatcac attttgataa gtaggagtgg aaagtatgtt
     7081 taaaaaatta ttcggaaaag gcaaagaagt tcagaaagat atcgcaattt atgcaccatt
     7141 aactggagaa tacgtgaaaa ttgaagatat tccagatcct gtattcgcac aaaaaatgat
     7201 gggcgaaggt tttggtatta atccaactga aggagaagtt gtgtctccaa ttgcaggacg
     7261 tgttgacaat gtctttccaa ctaagcatgc gattgggtta aaagcagata acggattaga
     7321 attattagtt catatcggtt tagacacagt tcaattagac ggtgaaggat ttgaagtgtt
     7381 agtgtctagt ggtgacgaag ttaacgtcgg agatccatta gtaagattca accttgaatt
     7441 tattaataat aacgctaaat ctgttatttc accaattata attacaaaca ctgatcaagc
     7501 agcttcaatt aatatttatg atgaaaatgc tgtgattaaa ggtgaaacaa aagtgattga
     7561 tgtgacaatg aactaatgaa aaactattcg ttttatcaat ttgtcatgac agttcgtggt
     7621 cgacacgacg ataaaggtcg tctagcagaa gagatatttg acgatcttgc tttcccaaaa
     7681 cacgatgatg attttaacat actgtctgat tatattgaga cacatggtga tttcacattg
     7741 ccaatgtctg tatttgatga tttatatgaa gaatatacgg aatggctaaa attttaacat
     7801 aatatttaat aatagttaga accagggtga tgcaatttgt tatcctggtt ttaatttaaa
     7861 ataaactaag ttgtgactaa aaattaatca attatagtga aatatggtgc gctatcttgc
     7921 ataaattgat atgattaact acacagaatt taaaagtaca taatacataa taaggaagtg
     7981 atacaatgga tgataagcaa cacacatctt catccgatga tgaacgcgct gaaattgcaa
     8041 caagcaatca agaccaacaa actaattcat cgaaacgcgt tcacttaaaa cgttggcaat
     8101 tcatatcaat tttaattggt acaatcctaa taacagctgt catcacagtt gttgcatata
     8161 tttttataaa tcaaaaaata agtggtttaa acaaaactga tcaagcaaac ttaaataaaa
     8221 ttgaaaatgt gtataaaatc ttaaatagtg attattacaa aaaacaggac tctgacaagt
     8281 taagtaaagc tgcaattgat ggcatggtca aagaattaaa agatccttat tctgaatatt
     8341 taacaaaaga acaaacgaaa tcctttaatg aaggtgtttc aggtgatttt gtaggtattg
     8401 gtgcagaaat gcaaaagaaa aatgatcaaa ttatggttac tagtcctatg aagggatctc
     8461 cagcagaacg tgctggcatt cgtcctaaag atgtcattac taaagtaaat ggaaaatcaa
     8521 ttaaaggtaa agcattagat gaagttgtca aagatgttcg tggtaaagaa aacactgaag
     8581 taactttaac tgttcaacga ggcagtgaag aaaaagacgt taagattaaa cgtgaaaaaa
     8641 ttcatgttaa aagtgttgag tataagaaaa aagataaggt tggagttatt actattaata
     8701 aattccagaa tgatacatca ggtgaattga aagatgcagt tcttaaagct cacaaagatg
     8761 gtttgaaaaa gattgtttta gatttaagaa ataatcctgg tggactacta gatgaagctg
     8821 ttaaaatggc aaatattttt atcgataaag gaaaaactgt tgttaaacta gaaaaaggta
     8881 aagatactga agcaattcaa acttctaatg actcgttaaa agaagcgaaa gacatggata
     8941 tatccatctt agtgaatgaa ggttcagcta gcgcttctga agtatttact ggtgcgctaa
     9001 aggactataa taaagctaaa gtttatgggt caaaaacatt cggtaaaggt gtcgtacaaa
     9061 ctacaagaga gtttaaggac ggttcattgt taaaatatac tgaaatgaaa tggttaacgc
     9121 cagatggtca ttatattcac ggtaaaggca ttaaaccaga cgttactatt gacacaccta
     9181 aatatcaatc tttaaatgtc attcctaata cgaaaacatt taaagttgga gacgatgata
     9241 aaaatattaa aactattaaa attggtttat cagctttagg ttataaagtt gataatgaat
     9301 caacgcaatt tgatcaagct ttagaaaatc aagttaaagc tttccaacaa acgaataaac
     9361 tcgaggtaac tggtgaattt aataaagaaa cgaataataa atttactgag ttattagttg
     9421 aaaaagctaa taaacatgat gatgttctcg ataaattgat taatatttta aaataagtga
     9481 tacacactgc taaaattgtt ttattatgtt aatgacacgc ctcctaaatt tgcaaagata
     9541 gcaatttagg aggcgtgttt atttttattg acgtctaact ctaaaagata taaattagac
     9601 atttacaaat gatgtaaata acgcaatttc tatcatcgct gttaacaatt catgctttaa
     9661 tatagtatga gcatatactt tttaaatagt attattcact agttttaaca atcgattaat
     9721 tggtatatga tacttt
//
LOCUS       DAPSKH010000080         9514 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPSKH010000080 DAPSKH010000000
VERSION     DAPSKH010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9514
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.080"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(104..1153)
                     /locus_tag="RPH49_002402"
     CDS             complement(104..1153)
                     /locus_tag="RPH49_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP synthase"
                     /protein_id="HDY5125521.1"
                     /translation="MIPTLEEIIDKYGNLVDYLKFDVTVEVYEDLLLLRSLSDLNEHQ
                     KMDRVSFIKKHLNSNFDYLLDDTEFRSINKIYSNLNIMTHINSQNNNFKRNPFINEEQ
                     LKSLLAIKKVDAHMSYDSNITSKALAEINKTQKRLVTKIDTLYNQSKKENEYVRLGEK
                     ISYTKLENHWKYLYNEIQFYNLNNQLISYVALEQEYAWAFLNELFYLIELYLKAFKGQ
                     KKTDYEFGKKLNEFIQSYVIILLIDIRLPVVRLYIIRDIVDTCEGEKDNYKRITLIEE
                     SIKKYRYVKDQIKRFKNGLEESLLNATLSIEQNMLKVKIDYYKAYCFPREKTKHNNIE
                     YNVSLFFKALDALKK"
     gene            1292..1582
                     /locus_tag="RPH49_002403"
     CDS             1292..1582
                     /locus_tag="RPH49_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125522.1"
                     /translation="MNKKSKQQEKLYNFIIAKSFQQPVGSTFTYGELRKKYNVVCSTN
                     DQREVGRRFAYWIKYTPGLPFKIVGTKNGSLLYQKIGINPCNNSTPLKGGDC"
     gene            1582..3369
                     /locus_tag="RPH49_002404"
     CDS             1582..3369
                     /locus_tag="RPH49_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001573627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HDY5125523.1"
                     /translation="MSYTLFEIGPFALDSFGWKETIPPKKDGDSEKVVRMASPIIVNA
                     RFSDPITGVEKLIITNNNGKKDIFESDILTTRNLPSLIKYGYSINEKYIRSLSYALQL
                     MRDRLPLSELYEGVGILETPFGYLISLDKVLKSIQFNQSSPSYPIVDSAYDLTPKGTF
                     DNWFNMYIDEVKGHLLLELAVIFGISALVTSFLKHKHEIEFAGILFSFTGQSSTGKST
                     AAALAVSVAGNPTKGNETLFRSWNATRNALEGYLSNNYGIPIVFDELSSTTLRDTTGL
                     LYSIAEGQGRQRSNVHGEVKTPKNWGTSVISTSEYSIFNDSAQNDGLRVRTIEINEQF
                     TTNATNADNIKKAVALNYGHVLPLVAKYLINREDEVIQWFYKEVDWFEAKLKDETNNT
                     GIRMFKRYAVITTSAKILGRVLSTDIDIANIRDYFIDYHTHTVSERSLADKAIDVIIQ
                     FVAQNRGKFSDEGALKNMFENYGLISLKDDHIEVKMIANVFKQMLNNHQFQDVNNVVN
                     ALRDKGFILADRGRQTTKRSVKDNSGKKQSLVFYHLKLDVEFASILGLTKDKSLIQNW
                     TPANDNKAAKELFKSANEGIGPSGVHEDF"
     gene            3603..4952
                     /locus_tag="RPH49_002405"
     CDS             3603..4952
                     /locus_tag="RPH49_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDY5125524.1"
                     /translation="MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQ
                     SGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRNLKNALKLIKLCQTYRVHILSVH
                     DGYFDMDQAFDRLKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYDYH
                     NGTFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYC
                     GRVNNQYGQFDNMFPSIVSTSIYEQAQRLRLQKQTKQTSSDNQLKQKIKCPCCNATLT
                     NMTIRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEVCRDFYQNQRIYTKI
                     KGAIDKRIKRQRNIEKHHILTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSING
                     HQIQHTIQNIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQAMQSSIA"
     gene            4974..6602
                     /locus_tag="RPH49_002406"
     CDS             4974..6602
                     /locus_tag="RPH49_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDY5125525.1"
                     /translation="MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFE
                     VKDIYADRGISGKSMNRPELQRMLKDAKEGNIDCVMIYKTNRLARNTSDLLKIVEDLH
                     KQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
                     LPLGYDKIPDSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPF
                     SISSITYILANPFYIGKIQFAKYKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQ
                     MRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKDGTKKRIRYYSCSNF
                     RNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVARVNQENKVDGAALHHDI
                     AYKQQQYDEVQTKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNE
                     DKSLFDAKQISKLLQHIFQDIKHMEKSRLKALYLSVIDRINIRKDGNHKKQFYVTLKL
                     NNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI"
     gene            7124..7474
                     /locus_tag="RPH49_002407"
     CDS             7124..7474
                     /locus_tag="RPH49_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002502216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125526.1"
                     /translation="MKTITQELKQYITHLFQLSNNEAWECEALEEAAENILPERFIND
                     SPLVHLTLETYTYYNDELHELSIYPFLMYANNQLISVGYLDHFDMDFLYLTDTQNIII
                     DERHLLKQGGQDHE"
     gene            7561..7872
                     /locus_tag="RPH49_002408"
     CDS             7561..7872
                     /locus_tag="RPH49_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002505017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDY5125527.1"
                     /translation="MKINRYITRGINESIPLDLQILLWHMVEKKDNQPHTDYLHIFKL
                     QEDENILSITHEQEQPTYKLEYHYTNYEKNQNALPKKVYVIREDDVDAFYYVMLLPEE
                     Y"
     gene            7887..8393
                     /locus_tag="RPH49_002409"
     CDS             7887..8393
                     /locus_tag="RPH49_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001092170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HDY5125528.1"
                     /translation="MNTIKSTIHTEAIFSDDEQHRYLLKKTWDEKKAACTVITMYPHL
                     DGVLSLDLTTVLILNQLANSERYGAVYLVNLFSNIRTPENLKHIKNPYDEHTDIHLMK
                     AISESDTVILAYGAYAKRPVVIDRVEQVMEMLKPHKKKVKKLINPVTNEIMHPLNPKA
                     RQKWILKS"
     gene            8445..9514
                     /locus_tag="RPH49_002410"
                     /pseudo
     CDS             8445..9514
                     /locus_tag="RPH49_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002494449.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         3553 a         1610 c         1476 g         2875 t
ORIGIN      
        1 gatttccaca acatttttcg tatttcagaa cgattaagac tacattatcc tggcttaata
       61 ttaattaatt ttaattatat ctataaatat tttcagtgaa aaactatttc tttaaggcat
      121 ctaatgcttt aaaaaacaac gatacattgt actcaatatt gttatgcttt gttttttctc
      181 taggaaagca gtaggcttta taataatcaa ttttaacttt caacatattt tgttcaatag
      241 ataaagttgc atttaataac gattcttcta atccattttt aaatctttta atctgatctt
      301 ttacgtatct atacttttta atagattctt ctatcagtgt aattcttttg taattatctt
      361 tttctccttc acatgtatct acaatgtctc taataatata taatctaaca acaggtaatc
      421 gtatatctat aagtaaaata atgacatatg attgaataaa ttcgtttaat tttttcccaa
      481 actcataatc tgttttcttt tgtcctttaa atgccttcaa atacaattct atcaaataaa
      541 atagttcatt taaaaaagcc caagcatatt cctgttctaa tgcaacataa ctaatcaatt
      601 gattattaag attataaaac tgaatctcat tatataaata tttccaatga ttctccaatt
      661 ttgtatacga tattttttct cctaaccgta catattcatt ttcttttttt gactgattat
      721 agagtgtgtc tatctttgta actaatcttt tttgcgtttt gtttatttct gccaatgctt
      781 ttgaagtaat atttgaatca taactcatat gtgcatctac tttctttatc gcgagtagtg
      841 atttcaattg ttcttcattt ataaatggat tacgtttaaa attattattt tgactattga
      901 tatgcgtcat gatatttaaa ttactgtaaa tcttattgat acttctaaac tcagtatcat
      961 ctaataaata atcgaaattt gagtttaaat gtttttttat aaatgaaact ctatccatct
     1021 tttgatgttc atttaaatcg cttaaacttc ttaataacaa caaatcttca taaacctcaa
     1081 ctgttacatc aaatttcaaa taatcaacta agtttccata cttatcaata atttcttcta
     1141 gcgtaggtat caatatatac cccccctccc cattttttgt tccgcgtcta atcataatgc
     1201 ttcatttatg cttattatag caatcaattg aagatagttt aacctatatg atattgattg
     1261 actccttaaa aattattgga ggaattttaa aatgaataag aaatctaagc agcaagaaaa
     1321 gctttataat tttataattg ctaaatcttt tcaacaacca gttggaagta cgttcactta
     1381 tggtgaatta agaaagaaat ataatgtggt ttgtagcacg aatgatcaac gtgaagtagg
     1441 acgtcgtttt gcttactgga ttaagtacac gccaggatta ccatttaaaa ttgtaggaac
     1501 aaaaaatggc agtttattat atcagaaaat agggataaac ccatgcaata atagcacgcc
     1561 tttgaaagga ggtgattgct aatgagttac acattgtttg aaattggccc atttgcttta
     1621 gattccttcg gttggaaaga aacgatacca cctaaaaaag atggtgacag tgaaaaagtg
     1681 gttagaatgg ctagccctat tattgttaat gcaagatttt ctgatccaat tactggtgtt
     1741 gaaaagttga ttattactaa caacaatggt aaaaaagaca tttttgagtc tgatatctta
     1801 acaacacgaa acttaccttc tttaattaaa tatggctaca gtattaacga gaagtatatt
     1861 agatcattga gttatgcctt gcaattgatg cgagatagat taccactttc tgaattatat
     1921 gagggtgtag gtatactaga gacacctttt ggctacttga tatcgctaga taaagttctc
     1981 aaatctattc aatttaatca gtcctcacct tcatacccta ttgtagatag tgcttatgac
     2041 ttaactccta aaggtacatt tgataattgg tttaacatgt atattgacga ggttaaaggt
     2101 catcttcttt tagaattggc agtcatattt gggatttctg ccttagtgac aagttttctg
     2161 aagcataaac atgaaatcga atttgcagga attctcttta gttttacagg tcaatcctca
     2221 accggtaagt caaccgcagc tgctttagct gtatcagtcg ctggtaaccc taccaaaggt
     2281 aatgaaactc tttttagaag ttggaatgcc acacgaaacg cacttgaagg ttatttgagt
     2341 aacaattatg gcattcctat agtatttgat gagctttcat ctacgacact tagagatacc
     2401 acgggtttgt tatattccat cgctgaaggt caaggtcgtc aacgttcaaa cgttcatgga
     2461 gaagttaaaa cgcctaagaa ttggggtact tctgtcattt caacgtcaga atacagtatt
     2521 tttaatgatt cagctcaaaa cgatggatta cgtgtaagaa ccatcgagat taatgaacaa
     2581 ttcactacaa atgcgaccaa tgctgacaat attaaaaaag ctgtagcact aaactatggt
     2641 catgttttac cgttagtagc taaatatctt ataaatcgtg aagatgaagt tattcaatgg
     2701 ttttacaagg aagtagattg gtttgaagct aaattgaaag atgaaacaaa caatacaggt
     2761 attcgtatgt ttaagcgtta tgcagtcatt acaacatctg cgaaaatatt aggtcgtgtt
     2821 ttatctacag atattgatat cgctaatata agagactact ttattgatta tcatactcat
     2881 acagtctctg aacgctcatt agctgataaa gctattgatg tcatcattca atttgtggca
     2941 caaaacagag gtaagttttc agatgaaggt gctttgaaaa atatgtttga gaactatgga
     3001 ttaatctcat taaaagatga ccatatcgaa gtaaaaatga ttgcgaacgt ttttaaacag
     3061 atgctaaaca atcatcaatt tcaagatgtt aataatgttg tcaacgcctt aagagataaa
     3121 ggtttcatat tagctgaccg tggacgccaa acaactaaaa gaagtgtcaa agataatagc
     3181 ggtaaaaaac aatcacttgt attttaccat ctaaaattag atgtagagtt tgcatctatc
     3241 ctgggattaa ctaaagataa gtcgttaatt caaaattgga caccggcaaa tgataacaaa
     3301 gctgcgaaag aactttttaa atccgctaat gaggggatag gcccttcagg agttcacgaa
     3361 gatttctgat tgtctttatc atacaaccgt gaagcatcaa actgaataat cgacgtattg
     3421 aagatagaac aaataacgga gtgaaaaaca tggatgaact tatcgagata ttagccgatt
     3481 tggtaattga agaaatcaat caaacgaatg actaatatgg acgcccaaca tctcattgat
     3541 gttgggctta tatatcaatt catctataaa tatatattat cactgtgaaa ggaggagccg
     3601 atatgaaaca agttataggc tatttacgtc aaagtacgat gaaacaacaa tctcttgcag
     3661 cacagaaaca agctatcgaa gcaatagccg aaaaacatca tattcaacat atcaactttt
     3721 atagcgacaa acaatcagga cgcaaagata atcgtagtgg gtatcgacaa atgacacaat
     3781 taattcaaca aggacaatgt gacatattat gctgttatcg tcttaatagg ttgcatcgta
     3841 atttgaaaaa tgcattaaaa ctcatcaaat tatgtcaaac atatcgtgtt catatcttaa
     3901 gtgtacatga tggttacttt gatatggatc aagctttcga ccgactcaag cttaatatct
     3961 tcatcagttt agccgaactt gaatcggata acattggaga acaagtcaga aatgggcttc
     4021 aagaaaaagc aaagcaaggt cgattgatta caacccatgc gccctttggt tacgattatc
     4081 acaacggaac attcatcatc aatcaaaatg agtcaccaac ggtaaaggct gtattcaatt
     4141 attacattaa aggtcatggt tataagaaaa ttgcacagtt attagaagaa gataacacgt
     4201 atatcaatcg acaaccctat caagttcgta acattatcat caatcctaat tattgtggtc
     4261 gtgtcaacaa tcaatatggt caattcgaca atatgtttcc ttctattgtt tccacaagta
     4321 tatatgagca agcgcagaga cttcgattgc aaaaacaaac caaacagaca tcttcggata
     4381 atcaactcaa acaaaaaatc aaatgcccat gttgtaatgc aacacttaca aatatgacca
     4441 ttagaaaaaa gaatcataca ttacgttact acgtctgtcc taaaaacatg aatgcttcac
     4501 gctttgtctg tgattttaaa ggcatcaatg cacaaacact tgaagataaa gtattagaag
     4561 tgtgccgaga cttttatcaa aatcaacgca tctacacaaa aattaaaggt gcgattgaca
     4621 aacgcatcaa aagacaaaga aacatagaaa aacatcacat attgactcaa gaacaactga
     4681 tagaaaagtt ggcacaaggc atcattgatg cagaaacgtt cagagaacaa acgcaatcat
     4741 tacgtcaaca accgcaacgc actacatcta taaatgggca tcaaatacaa cacaccattc
     4801 aaaatattat tcaaaaacgt ttcacgttaa acatattgta cccctatatt gaaaccattc
     4861 acattacgaa agataaaaat cttataggaa tctatttcaa aaatgaacca ctcaatatcg
     4921 tcaatcaagc catgcaatca tcgattgcat aaatgaagaa aggatgtaac ataatgcaac
     4981 aacttaaaac aaaacgtgtc ggtatctatg tacgtgtatc aacagaaatg caaagcacag
     5041 aaggttatag tatcgacgga caaatcaatc aaatcaaaga atactgtgac ttccatcatt
     5101 ttgaagttaa agatatatac gctgatcgtg gtatttcagg taaatctatg aacagacctg
     5161 agctccaacg tatgttgaaa gatgcaaaag aaggcaatat agattgtgtt atgatctaca
     5221 aaacaaaccg attagctcgt aatacatcgg atcttctgaa aatcgtcgaa gatttgcata
     5281 aacaaaatgt cgaatttttc agtttatcag agcgtatgga agtcaatact tcttctggta
     5341 aactcatgtt acaaatactt gcgagtttct cagaattcga acgtaataac attgtcgaga
     5401 atgtatttat ggggcaaacg agacgtgccc aagaaggcta ttatcaaggc aatttaccac
     5461 taggttatga caaaatacca gatagtaaac acgagctaat gattaaccaa catgaagcta
     5521 atattgtaaa atatatattc gagtcctatg ccaaaggaca tggctatcgt aaaatagcca
     5581 atgcattgaa tcacaaaggc tatgtcacta aaaagggtaa accttttagt attagttcta
     5641 tcacatatat attagctaac ccattctata tcggcaaaat tcaatttgcg aaatacaaag
     5701 attggagtga aaaacgtcgt aaagggctga atgataaacc agtgatagct gaaggtaagc
     5761 attcccccat tattaatcaa gatttatggg ataaagtaca aatgcgtaaa aaacaagtca
     5821 gtcaaaaacc ccaagttcat ggtaaaggaa cgaatctgct tacaggcatt atccattgtc
     5881 cccaatgtgg cgcacctatg gcagcaagca atacaacgaa tacacttaaa gatgggacca
     5941 agaaacgtat tcgttactat tcatgtagta attttcggaa caagggttcc aaagtatgtt
     6001 cggcaaacag tgtaagagct gatgtgattg aagattatgt aatgaagcaa atactcgaaa
     6061 tagtcaaaag tgataaagtc attcaacgcg ttgtagcacg tgttaatcaa gaaaataaag
     6121 ttgatggcgc tgcacttcat cacgatattg cttataagca acaacaatat gatgaagtac
     6181 aaaccaaact aaataacttg attaaaacca tagaggataa tccggactta acatcagtaa
     6241 tcagaccaag tattcaaaaa tatgaaaagc aactcaatga cattacgaat caaatcaacc
     6301 aactcaaaaa tcaacaaaat gaagataagt ctttatttga tgccaaacaa atcagtaaac
     6361 tattacaaca catctttcaa gatattaagc acatggaaaa atctcgactc aaagcattgt
     6421 acctatcagt gattgatcgt attaatatta gaaaagatgg taatcataaa aaacaattct
     6481 atgtcacact caaacttaat aacgaaatca ttaaacaact tttcaataat aaacaactcg
     6541 acgaagtgca tctcagcact tcgtctttat ttttgcccca aacactatat cttactattt
     6601 agctaataga atcattgtta taacaataat tttcactata ttctttcgct tattttatct
     6661 aactattttc aagaattgct ctttatcaat ttcaataaca cttatctaat gaaacagtta
     6721 ttgtcgtaat tttttcataa ctatacgatg cttatattga aattgctaaa gaacatccca
     6781 caatgatttt ttatcgggaa atgattggga tttgcagatt cgaagaaaca gaaggattgt
     6841 gcaagcacaa tcccaaaatc ccgttacttt ttataaataa ataatatata taaggaagca
     6901 gagacacaac cctatcatca atacttataa ataatgagtt gattgtttgt caaaataggc
     6961 ggaatttcag gatttccttg gcataccaac gtttgtagcg ggtttttata tggaattttc
     7021 tcttattccc accgggattc gtaataaatg acaaatcaaa tatatattat ctcaatgatg
     7081 tatatgaact acatcactat tacactatct aggaggcaat aatatgaaaa ccatcactca
     7141 agaactcaaa caatatataa cccacctatt ccaactatct aataacgaag cttgggaatg
     7201 tgaagcgctg gaggaagcag cagaaaatat tctaccggaa cgttttatta atgattctcc
     7261 actggtacat ctcacactcg agacttatac ctactataat gatgaactac atgagctaag
     7321 tatctatcca tttctaatgt atgccaataa ccaactcatc agtgtcggat acttagacca
     7381 ttttgacatg gactttctgt accttacaga tactcaaaat atcattattg atgaacgtca
     7441 tttactaaaa caaggaggtc aggaccatga ataattggat catagttgct caattatccg
     7501 tcacagttat caacgaaatc atcgacatca tgaaagaaaa gcagaaggga gggaaatagc
     7561 atgaaaatca atcgatacat cacaagagga attaatgaaa gtattccact agaccttcaa
     7621 atcttacttt ggcacatggt agaaaaaaaa gataaccagc ctcatacaga ttacctacac
     7681 atttttaaat tacaagaaga tgagaatata ctctcaatca cacatgaaca agaacaaccc
     7741 acatacaaat tggaatatca ctatacaaac tatgaaaaaa atcaaaatgc attacctaag
     7801 aaagtctacg tcattcgtga agatgacgtg gacgcttttt attatgtgat gcttttacca
     7861 gaagaatact aaaggaagtg acgatgatga atacaatcaa aagtacgata cacacagaag
     7921 ccatatttag cgatgatgaa cagcaccgct atttactcaa gaaaacatgg gatgaaaaga
     7981 aagctgcatg cacagtgata acgatgtatc ctcatttaga cggtgtatta tcactcgatc
     8041 tcacaactgt tcttatcctc aaccaattag ccaattcaga acgatacggt gctgtatatc
     8101 ttgtaaatct attctctaat attagaacac ccgaaaacct caaacatatc aaaaatccat
     8161 acgatgagca cactgatatt catttgatga aagcgattag tgaaagtgac acagtgattc
     8221 ttgcttatgg tgcctatgcg aagcgaccag ttgttatcga ccgtgtcgaa caagtgatgg
     8281 aaatgttaaa acctcataaa aagaaagtaa aaaagctcat caatccagta acaaatgaaa
     8341 ttatgcatcc actcaaccct aaggcacgtc aaaaatggat tttgaaatca tagcaaatac
     8401 atggaggtca atatggaaac aaaacaaatc aacatcgttt tactgtaaat gatattgttg
     8461 aaacaattcc tgacaatgaa ttcgacgaat tcagacatca ccgtggtgca acttcgtacc
     8521 atcctaaaat gatgttaaaa gtgattctat atgcctacac acaatctgta ttctcaggtc
     8581 gtaaaataga aaaaatgctt aatgatagca tccgaatgat gtggctatca caaaatcaaa
     8641 aaccttctta taaaataatt aatcgattta gagtaaatcc aaaagtagat gctttattag
     8701 aatctttatt tattcaattt tacagtcagt gtgtaaaaca aaatcttata gatgataaag
     8761 ctatttttat tgatggtaca aaaattgaag caaatgccaa tcgatataca tttgtatgga
     8821 aaaagagtat tcaaaaccat gaattaaaga tgaatgagga ttctaaagcc ctctaccatg
     8881 aattggtaac caataaaatc ataccggaaa ttaaagaaaa tcatgataat gaattaacaa
     8941 aagaagaaat agatttgatt ggtagtcact tagataaaga aatcgaagat ttaaaccaac
     9001 atatcaacaa tgaaaaatgt actaaaacaa gaaaacaaat acgtctcaaa agaactaaaa
     9061 tcaaaaaata caaaaagcaa atcaatgatt attttgagcg aaagtatcga tacgaatttc
     9121 aaaaatctat tttaaaggat agaaatagtt attctaagac agattatgat gcgacattta
     9181 tgagaatgaa agaagatcac atgaaaaatg gacaacttaa gccagggtat aatttacaaa
     9241 tagcaacaaa ttcccaattt gttttatctt ataatgtgta tcaaaatcca acggatacta
     9301 gaacgatgat tccattttta aattcaattc aagagaccta cggtcattta cctgaatata
     9361 ttgtagctga tgcaggttat ggtagtgaat caaattataa ggcaattata gatgacttta
     9421 atcgaacgcc actcataaca tatggaatgt ttataaaaga taaaactaaa aaatataaaa
     9481 gtgacatctt taatactcaa aattgtaact atga
//
LOCUS       DAPSKH010000081         9154 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPSKH010000081 DAPSKH010000000
VERSION     DAPSKH010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 9154)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9154)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9154
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.081"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            127..939
                     /gene="tagG"
                     /locus_tag="RPH49_002411"
     CDS             127..939
                     /gene="tagG"
                     /locus_tag="RPH49_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acids export ABC transporter permease
                     subunit TagG"
                     /protein_id="HDY5125529.1"
                     /translation="MSAIGTVFKEHVKNFYLIQRLAQFQVKIINHSNYLGVAWELINP
                     VMQIMVYWMVFGLGIRSNAPIHGVPFVYWLLVGISMWFFINQGILEGTKAITQKFNQV
                     SKMNFPLSIIPTYIVTSRFYGHLGLLLLVIIACMFTGIYPSIHIIQLLIYVPFCFFLT
                     ASVTLLTSTLGVLVRDTQMLMQAILRILFYFSPILWLPKNHGISGLIHEMMKYNPVYF
                     IAESYRAAILYHEWYFMDHWKLMLYNFGIVAIFFAIGAYLHMKYRDQFADFL"
     gene            1038..2141
                     /locus_tag="RPH49_002412"
     CDS             1038..2141
                     /locus_tag="RPH49_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HDY5125530.1"
                     /translation="MNVLIKKFYHLVVRILSKMITPQVIDKPHIVFMMTFPEDIKPII
                     KALNNSSYQKTVLTTPKQAPYLSELSDDVDVIEMTNRTLVKQIKALKSAQMIIIDNYY
                     LLLGGYNKTSNQHIVQTWHASGALKNFGLTDHQVDVSDKGMVQQYRKVYQATDFYLVG
                     CEQMSQCFKQSLGATEEQMLYFGLPRINKYYTADRATVKAELKHKYGITNKLALYVPT
                     YREDKADNRAIDKAYFENCLPGYTLINKLHPSIEHSDIDDVSSIDTSTLMLMSDIIIS
                     DYSSLPIEASLLNIPTIFYVYDEEAYDKVRGLNQFYKAIPDSYKVYTEEDLIMTIQEK
                     EHLLSPLFKDWHKYNTDKSLHQLTEYIDKMVTK"
     gene            2138..3199
                     /locus_tag="RPH49_002413"
     CDS             2138..3199
                     /locus_tag="RPH49_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDY5125531.1"
                     /translation="MRLTIIIPTCNNEATIRQLLISIESKEHYRILCIDGGSTDQTIP
                     MIERLQRELKHISLIQLQNASIATCINKGLMDIKMTDPHDSDAFMVINPTSIVLPGKL
                     DSLTAAFKNNDNIDMVIGQRAYNYHGEWKLKSADEFIKDNRIVTLMEQPDLLSMMSFD
                     GKLFSAKFAELQCDETLANTYNHAILVKAMQKATDIHLVSQMIVGDNDIDTHATSNDE
                     DFNRYITEIMKIRQRVMEMLLLPEQRLLYSDMVDRILFNNSLKYYMNEHPAVTHTTIQ
                     LVKDYIMSMQHSDYVSQNMFDIINTVEFIGENWDREIYELWRQTLIQVGINRPTYKKF
                     LIQLKGRKFAHRTKSMLKR"
     gene            3262..3660
                     /gene="tagD"
                     /locus_tag="RPH49_002414"
     CDS             3262..3660
                     /gene="tagD"
                     /locus_tag="RPH49_002414"
                     /EC_number="2.7.7.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate cytidylyltransferase"
                     /protein_id="HDY5125532.1"
                     /translation="MKRVITYGTYDLLHYGHIELLRRAREMGDYLIVALSTDEFNQIK
                     HKKSYYDYEQRKMMLESIRYVDLVIPEKGWGQKEDDVEKFDVDVFVMGHDWEGEFDFL
                     KDKCEVIYLKRTEGISTTKIKQELYGKDAK"
     gene            complement(3777..5072)
                     /gene="pbp4"
                     /locus_tag="RPH49_002415"
     CDS             complement(3777..5072)
                     /gene="pbp4"
                     /locus_tag="RPH49_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein PBP4"
                     /protein_id="HDY5125533.1"
                     /translation="MKNLISIIIILCLTLSIMTPYAQAANSDVTPVQAANQYGYAGLS
                     AAYEPTSAVNVSQTGQLLYQYNIDTKWNPASMTKLMTMYLTLEAVNKGQLSLDETVTM
                     TNKEYIMSTLPELSNTKLYPGQVWTIADLLQITVSNSSNAAALILAKKVSKNTSDFVD
                     LMNNKAKAIGMKNTHFVNPTGAENSRLRTFAPTKYKDQERTVTTARDYAILDLHVIKE
                     TPKILDFTKQLAPTTHAVTYYTFNFSLEGAKMSLPGTDGLKTGSSDTANYNHTITTKR
                     GKFRINQVIMGAGDYKNLGGEKQRNMMGNALMERSFDQYKYVKILSKGEQRINGKKYY
                     VENDLYDVLPSDFSKKDYKLVVEDGKVHADYPREFINKDYGPPTVEVHQPIIQKANTV
                     AKSMWAEHPLFTIIGGACLVAGLALIVHMIINRLFRKRK"
     gene            5493..7220
                     /locus_tag="RPH49_002416"
     CDS             5493..7220
                     /locus_tag="RPH49_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125534.1"
                     /translation="MKRENPLFFLFKKLSWPVGLIVAAITISSLGSLSGLLVPLFTGR
                     IVDKFSVSHINWNLIALFGGIFVINALLSGLGLYLLSKIGEKIIYAIRSVLWEHIIQL
                     KMPFFDKNESGQLMSRLTDDTKVINEFISQKLPNLLPSIVTLVGSLIMLFILDWKMTL
                     LTFITIPIFVLIMIPLGRIMQKISTNTQSEIANFSGLLGRVLTEMRLVKISNTERLEL
                     DNAHKNLNEIYKLGLKQAKIAAVVQPISGIVMLLTIAIILGFGALEIATGAITAGTLI
                     AMIFYVIQLSMPLINLSTLVTDYKKAVGASSRIYEIMQEPIEPTEALEDSENVLIDDG
                     VLSFEHVDFKYDVKKILDDVSFQIPQGQVSAFVGPSGSGKSTIFNLIERMYEIESGDI
                     KYGLESVYDIPLSKWRRKIGYVMQSNSMMSGTIRDNILYGINRHVSDEELINYAKLAN
                     CHDFIMQFDEGYDTLVGERGLKLSGGQRQRIDIARSFVKNPDILLLDEATANLDSESE
                     LKIQEALETLMEGRTTIVIAHRLSTIKKAGQIIFLDKGQVTGKGTHSELMASHAKYKN
                     FVVSQKLTD"
     gene            7579..8808
                     /locus_tag="RPH49_002417"
     CDS             7579..8808
                     /locus_tag="RPH49_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDY5125535.1"
                     /translation="MFLLINIIGLIVFLGIAVLFSRDRKNIQWQSIGILVVLNLFLAW
                     FFIYFDWGQKAVRGAANGIAWVVQSAHAGTGFAFASLTNVKMMDMAVAALFPILLIVP
                     LFDILMYFNILPKIIGGIGWLLAKVTRQPKFESFFGIEMMFLGNTEALAVSSEQLKRM
                     NEMRVLTIAMMSMSSVSGAIVGAYVQMVPGELVLTAIPLNIVNAIIVSCLLNPVSVEE
                     KEDIIYSLKNNEVERQPFFSFLGDSVLAAGKLVLIIIAFVISFVALADLFDRFINLIT
                     GLIAGWIGIKGSFGLNQILGVFMYPFALLLGLPYDEAWLVAQQMAKKIVTNEFVVMGE
                     ISKDIASYTPHHRAVITTFLISFANFSTIGMIIGTLKGIVDKKTSDFVSKYVPMMLLS
                     GILVSLLTAAFVGLFAW"
     gene            9063..>9154
                     /locus_tag="RPH49_002418"
     CDS             9063..>9154
                     /locus_tag="RPH49_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125536.1"
                     /translation="MFCYYKQHKGDNFSIEEVKNIIADNEMKVN"
BASE COUNT         3137 a         1297 c         1635 g         3085 t
ORIGIN      
        1 attttaaaga actagacaat aattttgata gcatccatgt atagtgatag tatttacaac
       61 aattattata atactattta gttaagtaga gaaatagtta aacatttgaa agtgtggttt
      121 aatggaatgt cagcaatagg aacagttttt aaagaacatg taaagaactt ttatttaatt
      181 caaagactgg ctcagtttca agttaaaatt attaatcata gtaactattt aggtgtggct
      241 tgggaattaa ttaaccctgt tatgcaaatt atggtttact ggatggtttt tggattagga
      301 ataagaagta atgcaccaat tcatggtgta ccttttgttt attggttatt ggttggtatc
      361 agtatgtggt tcttcatcaa ccaaggtatt ttagaaggta ctaaagcaat tacacaaaag
      421 tttaatcaag tatcgaaaat gaacttcccg ttatcgataa taccgacata tattgtgaca
      481 agtagatttt atggacattt aggcttactt ttacttgtga taattgcatg tatgtttact
      541 ggtatttatc catcaataca tatcattcaa ttattgatat atgtaccgtt ttgttttttc
      601 ttaactgcct cggtgacgtt attaacatca acactcggtg tgttagttag agatacacaa
      661 atgttaatgc aagcaatatt aagaatatta ttttactttt caccaatttt gtggctacca
      721 aagaaccatg gtatcagtgg tttaattcat gaaatgatga aatataatcc agtttacttt
      781 attgctgaat cataccgtgc agcaatttta tatcacgaat ggtatttcat ggatcattgg
      841 aaattaatgt tatacaattt cggtattgtt gccattttct ttgcaattgg tgcgtactta
      901 cacatgaaat atagagatca atttgcagat ttcttgtaat atatttatat gacgaaaccc
      961 cgctaaccat taataaatgg aagtggggtt catttttgtt tataatttaa gtaaataaca
     1021 tattaagttg gtgtattatg aacgttttaa taaagaaatt ttatcatttg gtagttcgaa
     1081 tactttctaa aatgattacg cctcaagtga ttgataaacc gcatatcgta tttatgatga
     1141 cttttccaga agatattaag cctatcatca aagcattaaa taattcgtcg tatcagaaaa
     1201 ctgttttaac aacaccaaaa caagcgcctt atttatctga acttagcgac gatgttgatg
     1261 tgatagaaat gactaatcga acattggtaa aacaaattaa ggctttgaaa agcgcgcaga
     1321 tgattattat cgataattat tacctattac taggtggata taataagact tctaatcaac
     1381 acattgttca aacgtggcat gcaagtggtg cattaaaaaa ctttggatta acagatcatc
     1441 aagtcgatgt gtctgacaag ggaatggttc agcagtaccg taaagtttat caagcgacgg
     1501 atttttactt agtgggttgt gaacaaatgt cacaatgttt taaacagtct ttaggtgcaa
     1561 cagaagagca aatgttgtat tttgggcttc cgagaattaa taaatattac acagctgata
     1621 gagcaacggt taaggcagag ttaaagcata aatatggaat tacaaataag ttggcattat
     1681 atgtaccaac atatagagaa gataaagcag ataatagggc tattgataaa gcttattttg
     1741 aaaactgttt accaggatat acactgatta ataaattaca tccatcaatt gaacattcag
     1801 acattgatga cgtatcttca atcgacacgt ctacattaat gctaatgtca gatataatta
     1861 ttagcgacta tagttcgctg ccaatagaag ctagcttgtt aaatattcca actatatttt
     1921 atgtgtatga tgaagaggca tatgataaag tgagaggcct gaatcaattt tacaaagcaa
     1981 taccggatag ctacaaagtg tatactgaag aagatttaat aatgacgata caagaaaaag
     2041 aacatctatt aagtccgtta tttaaagatt ggcataagta taatactgat aaaagtttac
     2101 atcagctcac agaatatata gataagatgg tgacaaaatg aggcttacga taatcatacc
     2161 tacatgtaat aatgaggcaa caattcgaca attgttaata tctattgaga gtaaagaaca
     2221 ctatagaatc ctttgtattg atggaggttc taccgatcaa acaattccta tgattgaacg
     2281 gttacaaaga gaactcaagc atatttcatt aatacaatta caaaatgctt cgatagctac
     2341 gtgtattaat aaaggtttga tggatatcaa aatgacagat ccacatgata gtgacgcatt
     2401 tatggtcata aatccaacat caatcgtatt gccaggtaaa ttagatagtc taactgcagc
     2461 tttcaaaaat aatgataata ttgatatggt aatagggcag cgagcttaca attaccatgg
     2521 tgaatggaaa ttgaaaagtg ctgatgagtt tattaaagac aatcgaatcg ttacattaat
     2581 ggaacaacca gatttgttat caatgatgtc ttttgacgga aagttattca gtgctaaatt
     2641 tgctgaatta cagtgtgacg aaactttagc taacacatac aatcacgcaa tacttgtcaa
     2701 ggcgatgcaa aaagctacgg atatacattt agtttcacag atgattgtcg gagataacga
     2761 tatagataca catgctacaa gtaacgatga agattttaat agatatatca cagaaattat
     2821 gaaaataaga caacgagtca tggaaatgtt actattacct gaacaaaggc tattatatag
     2881 tgatatggtt gatcgtattt tattcaataa ttcattaaaa tattatatga atgaacaccc
     2941 agcagtaacg cacacgacaa ttcaactcgt aaaagactat attatgtcta tgcagcattc
     3001 tgattatgta tcgcaaaaca tgtttgacat tataaataca gttgaattta ttggtgagaa
     3061 ttgggataga gaaatatacg aattgtggcg acaaacatta attcaagtgg gcattaatag
     3121 gccgacttat aaaaaattct tgatacaact taaagggaga aagtttgcac atcgaacaaa
     3181 atcaatgtta aaacgataac gtgtacattg atgaccataa actgcaatcc tatgatgtga
     3241 caatatgagg aggataactt aatgaaacgt gtaataacat atggcacata tgacttactt
     3301 cactatggtc atatcgaatt gcttcgtcgt gcaagagaga tgggcgatta tttaatagta
     3361 gcattatcaa cagatgaatt taatcaaatt aaacataaaa aatcttatta tgattatgaa
     3421 caacgaaaaa tgatgcttga atcaatacgc tatgtcgatt tagtcattcc agaaaagggc
     3481 tggggacaaa aagaagacga tgtcgaaaaa tttgatgtag atgtttttgt tatgggacat
     3541 gactgggaag gtgaattcga cttcttaaag gataaatgtg aagtcattta tttaaaacgt
     3601 acagaaggca tttcgacgac taaaatcaaa caagaattat atggtaaaga tgctaaataa
     3661 attatataga actatcgata ctaaacgata aattaacgta ggttattata aaataaatat
     3721 aaaacggaca agtttcgcag ctttataatg tgcaacttgt ccgtttttag tatgttttat
     3781 tttctttttc taaataaacg attgattatc atatgaacaa ttagtgctaa tccagcgact
     3841 aggcatgcac caccaatgat agtgaataat ggatgttctg cccacatact tttagcaaca
     3901 gtatttgcct tttgaataat tggctgatga acttctacag ttggaggtcc ataatcttta
     3961 ttaataaatt ctcttggata gtccgcgtgt actttaccat cttcgactac aagtttataa
     4021 tcttttttac taaaatcact tggtaaaaca tcgtaaagat cgttttcaac ataatatttc
     4081 ttaccattta tcctttgctc acctttagac aatattttta catatttata ctgatcaaat
     4141 gagcgttcca ttaatgcatt ccccatcata ttacgttgct tctcgccacc aaggttttta
     4201 tagtctcccg cacccatgat aacttgatta attctaaatt tacctcgttt ggtagtaatc
     4261 gtatggttgt aatttgctgt atcacttgat ccagttttta aaccatctgt accaggcaaa
     4321 ctcatttttg caccttccaa tgaaaagttg aatgtgtaat acgtaactgc atgcgttgtt
     4381 ggtgctaact gctttgtaaa gtctaatatt ttaggtgtct ctttaatcac gtgtaaatct
     4441 aaaatggcat agtctctagc agtcgttaca gtacgttctt ggtctttata ctttgttggt
     4501 gcaaatgtac gtaatcttga attttcagca cccgttggat tgacgaaatg tgtatttttc
     4561 attccgatag ctttagcttt gttattcatt aaatcaacga aatcgctggt gttttttgat
     4621 accttcttag ctaaaattaa tgccgcggca ttactagaat tagatactgt aatttgtaat
     4681 aggtctgcga ttgtccatac ttgtccagga tatagtttcg tattactcaa ctcaggtagt
     4741 gtagacataa tatattcttt gttcgtcatt gtgacagttt catcaagtga aagctgcccc
     4801 ttatttacag cttccaatgt taagtacatt gtcattaatt tagtcataga cgctggattc
     4861 cacttagtat cgatattgta ttgatacagt aattgtccag tttgactaac attaacagca
     4921 ctcgtcggtt cgtatgcagc cgacaaacct gcataaccat attgatttgc tgcttgtaca
     4981 ggggttacgt cactgttagc agcttgtgca tatggtgtca taatacttaa tgttaaacat
     5041 aaaatgatga taatagatat taaatttttc ataaagcgtt aatcttccct tttccaattc
     5101 ttaaatattc cctaaaagca atggtcattc ctaattacgg aaatcattgc taattcactt
     5161 caccttaatt aaattgttga aaattaagtt tcttgcggtt tatttgaaaa ataatgcaaa
     5221 tatattacgt gtgtagctaa aggtgttata atgtttgtac gaagagcaaa cttactcaaa
     5281 agcgattaat tatcatgttt taatataaaa actttgagaa gttattacaa aaaatgcaat
     5341 agaaatattc tatcatataa atgttatgaa cggtattttg gggcaatact ttatttgatt
     5401 tttaaagttt tgttgggaga aagtatatga tagaaatgca tgtatctatc taaatgaatt
     5461 aactataaat ttcaaacaaa agaggtaaaa ctatgaaacg agaaaatcca ttgtttttct
     5521 tatttaaaaa actatcatgg ccagtgggtc ttatcgttgc agctatcact atttcatcac
     5581 tagggagctt aagtggacta ttagtgccac tgtttactgg acgaattgta gataaatttt
     5641 ccgtgagcca tatcaattgg aatctaatcg cattatttgg tggtatcttt gtcatcaatg
     5701 ctttattaag cggattaggt ttatatttat taagtaaaat tggtgaaaaa attatttacg
     5761 cgatacgctc agttttatgg gagcatatca tacaattaaa aatgccattc tttgataaaa
     5821 atgaaagtgg tcaattaatg agtcgattaa ctgacgatac gaaagtgata aatgaattta
     5881 tttcacaaaa gctacccaac ttattaccat caatcgttac attagttggg tcactaatca
     5941 tgttatttat tttagattgg aaaatgacat tattaacatt tataacgata ccgatatttg
     6001 ttttaattat gattcctcta ggacgtatta tgcaaaaaat atcgacaaat acacaatctg
     6061 aaattgcaaa ctttagtggt ttgttagggc gtgtcctaac tgaaatgcgt cttgttaaaa
     6121 tatcaaatac agagcgactt gaattagata atgcacataa aaatttgaat gaaatatata
     6181 aattaggttt gaaacaggct aaaattgcgg cagttgtaca accaatttca ggtattgtta
     6241 tgttgctaac aattgcaatt attttaggtt ttggtgcatt agaaattgcg actggtgcaa
     6301 tcactgcagg tacattaatt gcaatgatat tttatgttat tcaattatcg atgcctttaa
     6361 tcaatctttc aacgttagtt acagactata aaaaggcagt cggtgcaagt agtagaatat
     6421 acgaaatcat gcaagaacct attgaaccga cagaagctct tgaagattct gaaaatgtat
     6481 taattgatga cggtgtgttg tcatttgaac atgtagactt taaatatgat gtgaagaaaa
     6541 tattagatga tgtgtcgttc caaatcccac aagggcaagt gagtgctttt gtaggtcctt
     6601 ctggatctgg taaaagtacg atatttaatc tgatagaacg tatgtatgaa attgagtcag
     6661 gtgatattaa atatggcctt gaaagtgtct atgatatccc gttatctaag tggcgacgca
     6721 aaattggata tgttatgcaa tcaaattcga tgatgagtgg tacaattaga gacaatattt
     6781 tatacggaat taatcgtcat gtttcagatg aagaacttat taattatgct aaattagcga
     6841 actgtcatga ttttatcatg caatttgatg aaggatatga cacgcttgta ggtgaacgag
     6901 gattgaaact gtctggcgga caacgtcaac gtattgatat tgctagaagt tttgttaaaa
     6961 atcccgatat tttgttactt gatgaagcaa cagctaatct cgatagtgaa agtgaattga
     7021 aaattcaaga agctttagaa acattgatgg aaggtagaac aacgattgtc attgcgcatc
     7081 gtttgtctac aattaaaaaa gccggtcaaa ttatattctt agacaaagga caggtaacag
     7141 gtaaaggtac gcattcagaa ctaatggcat cacatgcgaa gtataaaaac tttgtagtgt
     7201 ctcaaaaatt aacagattaa ttttatatat ataagtaagc ttggagcaag tacagatata
     7261 ccatcgagga aattaaagcg tggcacattg atggatatag atgttaataa attgcttcaa
     7321 gcttttgtct attttaaatc atttgagaag ttacgacata ataattctta aattaatgaa
     7381 atcgatattt taagaaaaaa atgctcatgg tataatacaa gttataagca aacatacata
     7441 tattaaatac tgtagccacg agtcataatt cttcatattt tacatagcaa tttaactgat
     7501 tttagagtcc acggtacaga agtttgatat ttcaatgttt ctaaattttt aaaaaattaa
     7561 atcataggtg ggtgccaaat gtttttatta atcaacatta ttggtctaat tgtatttctt
     7621 ggtattgcgg tattattttc aagagatcgc aaaaatatcc aatggcaatc aattgggatc
     7681 ttagttgttt taaacctgtt tttagcatgg ttctttattt attttgattg gggtcaaaaa
     7741 gcagtaagag gagcagccaa tggtatcgct tgggtagttc agtcagcgca tgctggtaca
     7801 ggttttgcat ttgcaagttt gacaaatgtt aaaatgatgg atatggctgt tgcagcctta
     7861 ttcccaatat tattaatagt gccattattt gatatcttaa tgtactttaa tattttaccg
     7921 aaaattattg gaggtattgg ttggttacta gctaaagtaa caagacaacc taaattcgag
     7981 tcattctttg ggatagaaat gatgttctta ggaaatactg aagcattagc cgtatcaagt
     8041 gagcaactaa aacgtatgaa tgaaatgcgt gtattaacaa tcgcaatgat gtcaatgagc
     8101 tctgtatcgg gagctattgt aggtgcgtat gtacaaatgg taccaggaga actggtacta
     8161 acggcaattc cactaaatat cgttaacgcg attattgtgt catgcttgtt gaatccagta
     8221 agtgttgaag agaaagaaga tattatttac agtcttaaaa acaatgaagt tgaacgtcaa
     8281 ccattcttct cattccttgg agattctgta ttagcagcag gtaaattagt attaatcatc
     8341 atcgcatttg ttattagttt tgtagcgtta gctgatctat ttgatcgttt tatcaatttg
     8401 attacaggat tgatagcagg atggataggc ataaaaggta gtttcggttt aaaccaaatt
     8461 ttaggtgtgt ttatgtatcc atttgcgcta ttactcggtt taccttatga tgaagcgtgg
     8521 ttggtagcac aacaaatggc taagaaaatt gttacaaatg aatttgttgt tatgggtgaa
     8581 atttctaaag atattgcatc gtatacacca caccatcgtg cggttattac aacattctta
     8641 atttcatttg caaacttctc aacgattggt atgattatcg gtacattgaa aggcattgtt
     8701 gataaaaaga catcagactt tgtatctaaa tatgtgccta tgatgctatt atcaggtatc
     8761 ctagtttcat tattaacagc agctttcgtt ggtttatttg catggtaata tgttgaagtg
     8821 tgacttcgat aatacatttt aactaataaa tatgttcagg catgtcgtct attgatatag
     8881 gtgagatgct tggacttttt tattattgat ataaagatat ttaaatattt ttaaagttac
     8941 cgaaattgaa gcattataaa aaccaagtgc acatggtaat acacttggct tttatgggaa
     9001 atgaatatta ttgtacatat gacagtaagg actaggtaca gtcatagtac ttcgagcaaa
     9061 atttgttttg ttattataaa caacacaaag gagataactt ctctattgaa gaagttaaaa
     9121 acattatagc agacaatgaa atgaaagtaa atta
//
LOCUS       DAPSKH010000082         8907 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPSKH010000082 DAPSKH010000000
VERSION     DAPSKH010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8907
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.082"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            22..1545
                     /locus_tag="RPH49_002419"
     CDS             22..1545
                     /locus_tag="RPH49_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125537.1"
                     /translation="MSKKLKIIIPIIIVLLLIGGIAWGVYAFFANTPKNTYLKSEQQT
                     AKMYKDYFNDRFENEVKFQEKMKDNSFLSSLELSADASDEIVKGLGIPKSVVNASKIK
                     MSYGHDPKKEKSMINLEPTIADSELGNFQLAADKDKHYFESPLFKGKYSVNNSDLLST
                     YSKLTGEDEETAKENGITNQQLNLNTLFSNAQAQQSDYSKIAEKYSELIVDKLDDDNF
                     DKGKKEEIKVNGEKYKVRPVTLTLSRADTKKITLAVLEEAKKDKDLKKLMEEQGATKD
                     FEKDIKKAIDDVKETKKDEFAKIQSKIYTEKHTIVKREITITDKENNKTKIKGTNTLE
                     DNKLKLDYALDFDQDKYTYAEAKYTIKGVSSKEKDNKYSDKYEFGKKTEYDESKIKLD
                     NQEKVDGTKRQDKGKITVALDKYSDENEFTFENNIDSDVKNNTQKSTLNIGIKYAEEP
                     INFILKSSTKLKADIDFDDSGAKDFNSLSSKDREKLEKEIEKNGGKMFESILKKASK"
     gene            1613..2779
                     /locus_tag="RPH49_002420"
     CDS             1613..2779
                     /locus_tag="RPH49_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125538.1"
                     /translation="MKTIHLFRIYHSFLLKKWYLIIYLLFILAALVITLTTIQHVTED
                     DNHFNIGVVDKDQSSETKLILNSIGKGSNLGKNVSIKAYDDKQAHTLLKKHKLQGYFV
                     FDKGMTKAFYKQGELPISVYTYDQQSMKSVVLSQLTDSVYQRLMRSMGGILAFQDLAP
                     KASHSDSINVMTDLLITGLNRSGAFNLEPIHLYDTGSYYAITGFLTTVFIFALSLFTV
                     LKMNQDTVLKARLKMFHFSKERLLIIRALITWFYTMLWSIVGVVWIVFSIPNTFELYN
                     WPTLAIHLSYYVTFLILWLLLIELLTTGLLNSISKVILAIVILVLSGLTIPTIFLQHI
                     ANGVFNIQPFAVVTNQLLEIILNNYILELHPSFYLSFIALLIINLAVLVWRYRQ"
     gene            2776..3696
                     /locus_tag="RPH49_002421"
     CDS             2776..3696
                     /locus_tag="RPH49_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125539.1"
                     /translation="MKPYIQLVVFKQWLQYILLVTTIVIALVLIGIGYRVAHDNFKIP
                     ITIQDLDQTTASKSFVNKIKQSDYVTIKKVDEDESYIEDDVTKKEAILSMQIPKGFSQ
                     KLKENRLKETIQLYGRDDFIGGIAVEIVSSSLYEQQIPNIIYEHLEDMKQHQSIDAIN
                     KSYHKHTPESKIKFVSLTKQAQHSISISLIFAVILFVSAVQVVLHYRLNQQAALQRLS
                     QYHLSRFKLYSTYVMTHTILLLLVLLAVSLYLSQPLSLIFYLKSLLLILIYEIGIVFI
                     LFHIQTISHRLFMTFIYALAMGIVYLTIFM"
     gene            3710..4369
                     /locus_tag="RPH49_002422"
     CDS             3710..4369
                     /locus_tag="RPH49_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125540.1"
                     /translation="MIEINNLSKRYRNKQIFNHLTMSFDSNRLTVLLGDNGAGKSTLL
                     RMIAGIEKANDGTINYFGEKWNQRQIQNHIGYVPQDIALFEHMTVAENIKFFKSLCKN
                     PINDTTINEYLQQLNFDDTSAKVSTLSGGNKRKINILVGLLGKPRILILDEPTVGIDL
                     KSRHDIHQLLNIMKSKCLIILTTHHLDEVEALADDIKLIGQDPFYQHVLEDKQWTYTY
                     Y"
     gene            complement(4421..5368)
                     /gene="lytM"
                     /locus_tag="RPH49_002423"
     CDS             complement(4421..5368)
                     /gene="lytM"
                     /locus_tag="RPH49_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine-glycine endopeptidase LytM"
                     /protein_id="HDY5125541.1"
                     /translation="MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSAQSQD
                     VSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANAN
                     GSGQTYVNPATTGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNQAYNSHDGNG
                     KVNYPNGTSNQNGGSASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPE
                     NSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQ
                     IAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPMSYLQSR"
     gene            complement(5694..6686)
                     /locus_tag="RPH49_002424"
     CDS             complement(5694..6686)
                     /locus_tag="RPH49_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="linear amide C-N hydrolase"
                     /protein_id="HDY5125542.1"
                     /translation="MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTG
                     TTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKADAMNITQNE
                     IVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGQSVEVSFKEGE
                     VVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATANLLEGVTIEPLGNEAGTFGLP
                     GGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMY
                     QTVINLTTRTLYIKYYGSNEIVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ"
     gene            6920..8296
                     /locus_tag="RPH49_002425"
     CDS             6920..8296
                     /locus_tag="RPH49_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDY5125543.1"
                     /translation="MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTS
                     PAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALL
                     IIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIAT
                     NFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLT
                     QGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVL
                     NSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLII
                     GPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVG
                     LATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYM
                     IIPKTVKS"
     gene            complement(8424..8816)
                     /locus_tag="RPH49_002426"
     CDS             complement(8424..8816)
                     /locus_tag="RPH49_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125544.1"
                     /translation="MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFG
                     DTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLM
                     LTDFQKENYNKYIQGQKQRVIFENGHFV"
BASE COUNT         2983 a         1527 c         1399 g         2998 t
ORIGIN      
        1 aaataattgg gaggaagcaa aatgtctaaa aagttaaaaa ttataattcc tattattatt
       61 gtcttattat taataggtgg aatcgcatgg ggagtttatg cattttttgc aaacacaccg
      121 aaaaatacat acttaaaaag tgaacaacaa actgcaaaaa tgtataaaga ttattttaat
      181 gaccgttttg aaaacgaagt gaagttccaa gaaaagatga aagataattc atttttatct
      241 tcattagaat taagcgcaga tgcatcagat gaaattgtta aggggcttgg tattcctaaa
      301 tctgttgtta atgcttcgaa aattaaaatg tcatatggac atgatcctaa aaaagagaaa
      361 tcaatgatta atcttgaacc aacaatagca gactctgaat tagggaattt ccagttagct
      421 gcagataaag ataagcatta tttcgaatca ccattattta aagggaaata tagtgttaat
      481 aattctgatt tattatcaac ttattcaaaa cttacaggtg aagatgaaga aacagcaaaa
      541 gaaaatggta ttacaaacca acaactaaat ttaaatactc tttttagtaa tgctcaagca
      601 caacaaagtg actacagcaa aattgccgaa aaatattccg aacttattgt cgacaaatta
      661 gatgacgata attttgataa aggtaaaaaa gaagaaatta aggttaatgg tgaaaagtac
      721 aaagttagac ctgtcacgtt aacacttagc agagctgaca ctaaaaaaat tacattagct
      781 gtattagaag aagctaaaaa ggataaagac cttaaaaaat taatggaaga acaaggtgct
      841 acaaaagact ttgaaaaaga catcaaaaaa gcaattgacg atgtcaaaga aactaaaaaa
      901 gatgaatttg ctaaaattca atctaaaatt tataccgaaa aacatacgat tgtaaaacga
      961 gaaattacta ttacagacaa agaaaataat aaaactaaaa tcaaaggtac taatacttta
     1021 gaagacaata agttaaaact agattacgca cttgatttcg atcaagataa atacacgtat
     1081 gctgaagcga aatatacaat taaaggcgta tcttctaagg aaaaagacaa taaatacagt
     1141 gataaatacg aatttggtaa aaagacagaa tatgatgaat caaaaatcaa attagataac
     1201 caagagaaag tagatggcac aaaacgtcaa gataaaggta aaattactgt cgcattagat
     1261 aaatatagcg acgaaaatga attcactttt gaaaataata tagattctga cgtaaaaaat
     1321 aacactcaga aatctacgtt aaatatcggc atcaaatatg ctgaagaacc aattaatttc
     1381 attttaaaat ctagcacaaa attgaaagca gatattgatt ttgatgatag tggtgcgaaa
     1441 gatttcaata gtctatcttc aaaagatcgt gaaaaacttg aaaaagaaat cgaaaaaaat
     1501 ggcggcaaaa tgtttgaatc aattttaaaa aaggcatcta aataactaaa atataaaaat
     1561 aagattggaa ggtcatcttg cctttcaatc ttatcattgg aggagtggtt aaatgaaaac
     1621 aatacatttg tttcgcatct accactcttt tttattgaaa aagtggtatt tgattatcta
     1681 tttactattt atattagcgg cactcgttat tacattaacg acaatccaac atgtaacaga
     1741 agatgacaat cattttaata taggtgtcgt agataaagat caatcaagtg aaacgaaatt
     1801 aatcttaaac tctattggta aagggagtaa cctaggaaaa aatgtgagca ttaaagcata
     1861 tgatgataag caagcacata ctttgttaaa aaaacataaa cttcaaggtt attttgtttt
     1921 tgataaaggt atgaccaagg cattttataa acaaggcgaa ctaccaattt cagtatatac
     1981 atatgatcaa caatccatga aaagtgtcgt gctatctcag ctaacagatt ctgtttacca
     2041 acgtcttatg cgatcaatgg gtggcatctt agcttttcaa gacttagcac cgaaagcatc
     2101 acattctgac agtatcaatg ttatgactga tttgctgatt acaggattaa accgttcagg
     2161 tgcatttaac ttagaaccga ttcatttata cgatacgggc agttattatg caattacagg
     2221 atttttaaca acggtattca tctttgcact atctttattt acagttttga aaatgaatca
     2281 agatactgta ttgaaagcgc gattgaaaat gtttcatttt tctaaagagc gtttgttaat
     2341 cattcgtgcg ttgattacat ggttttatac tatgttatgg agtatcgttg gtgtagtttg
     2401 gattgtgttc agtattccga atacctttga attatataat tggccaacgt tagccattca
     2461 tttaagctat tatgttacct ttttaatact gtggttatta ctcatcgaac ttttaactac
     2521 aggcttgttg aatagtatta gtaaagtcat attagctatt gtcatcctgg tgttatctgg
     2581 tttaacaata cctacgattt ttttacaaca tatagcaaat ggcgttttca atattcaacc
     2641 gttcgcagtt gtaacaaatc aattgttaga aattatttta aacaactaca ttttagaact
     2701 gcaccctagt ttctatctta gcttcatcgc acttttgata attaatttag ctgtattggt
     2761 ttggaggtat cgtcaatgaa gccttatata caacttgttg tgttcaagca atggttacaa
     2821 tacatcttgc tcgtaacaac cattgtcatc gcactcgtac ttattggtat cggttaccgt
     2881 gtagcacatg acaacttcaa aataccgatt accattcaag atttagacca aaccactgca
     2941 tcaaaatcat tcgtcaataa aattaaacaa tctgactatg taactattaa aaaagtcgat
     3001 gaagatgaaa gctatattga agatgatgtt actaaaaagg aagctatttt aagtatgcaa
     3061 attcctaaag gtttctctca aaaattaaaa gagaaccgtt taaaagaaac gatacagtta
     3121 tatggtagag atgactttat aggtggtatt gctgtagaaa ttgttagtag ttcattatat
     3181 gagcagcaaa ttcctaacat tatttatgaa caccttgagg atatgaaaca gcatcaatcc
     3241 atcgatgcta tcaacaagtc ctatcataaa catacacctg aatctaaaat caaatttgtg
     3301 tcgcttacta aacaagcaca acactctatt tcaattagct taatctttgc ggtgatttta
     3361 tttgttagcg ctgttcaagt agtacttcat tatcgtttaa accaacaagc agcattgcaa
     3421 cgattatcac aatatcattt aagccgtttc aaactatata gtacttatgt aatgacacat
     3481 acgattttgt tattgttggt actattggca gttagtctat atttgtctca accactcagc
     3541 ttaatatttt acttaaaatc actgttactt atattgattt atgagatagg tatcgtcttt
     3601 atcttattcc atattcaaac aataagtcat cgattattca tgacatttat atatgcactt
     3661 gctatgggta tcgtatactt gaccattttc atgtaaagga gcgtaactga tgatagaaat
     3721 taataacctt tcaaagcgtt accgtaacaa acagattttc aatcatttaa ccatgtcctt
     3781 tgatagtaat cgattaaccg tattacttgg tgataatggc gctggaaaat caacattact
     3841 tcgtatgatt gctggtattg aaaaagctaa tgatggaact atcaactatt tcggcgaaaa
     3901 atggaatcaa agacaaatac aaaatcacat cggttatgtg ccacaagaca ttgcgttatt
     3961 tgaacacatg acagtggctg aaaacattaa attttttaaa tcactttgta aaaatccaat
     4021 taacgataca actatcaacg aatatttaca gcaattaaat tttgatgata cgtctgccaa
     4081 agtatctaca ttgtccggtg ggaataaacg taaaattaat atattagtag gtttactagg
     4141 taaacctcga attctcattt tagatgaacc gacagttggt attgatttaa aatctagaca
     4201 tgacatccac caactactta acattatgaa atctaaatgt ttaattatat taactaccca
     4261 tcatttagat gaagttgaag cacttgcaga tgatatcaag ttaattggcc aagatccttt
     4321 ttatcaacat gttttagagg acaaacaatg gacttatacc tattattaaa acgaaaaaat
     4381 cccaagctgc gtatgatatc gcaacttggg attttctgta ttatctactt tgcaagtatg
     4441 acattgggtc tactgcatat tgattaccga tgccaccaga catacgttgg aagtgtacgt
     4501 gaggcgctgt tgaattaccc gtactacctg aatatgcaat ttggtcacca gctttgactt
     4561 tatcaccagc tgaaacagtt aaacgattat tatgcatata ccattggtag ttattactgt
     4621 tcgcttcttt aatcgttact tgattaccac caccatagtt actccaacct gcttgtacta
     4681 ctgtaccatc agttaatgag taaactggtg aattttcagg cattgcatag tcgacaccgt
     4741 aatgcgcacc accaccgtga tattgtccat atggttgtag ttgtttacga cttgttaacc
     4801 agcttgcgtc tttcgcatga ccactagctg tcgctttact tgctgatccg ccattttgat
     4861 tagacgtgcc attagggtaa ttgacctttc cattaccatc atggctgtta tacgcttggt
     4921 tgttactatg tgaataatag ctcgcgtctg gacctacatt tgattgataa ccatattgat
     4981 taatgtgctg ttggctttga ctcgctgtgt agtcattgtt atctcctgtt gttgctggat
     5041 tcacatatgt ttgaccgctt ccattggcat ttgcattttt tggataacag ttataaaaat
     5101 aatgcgtatg tccttgagca tctacgaatg tatagctata ttctttatta tcaaacattg
     5161 cttgattcca gttaccatca ggtgtgtgat gataatcccc attagaatca attgtataat
     5221 aagtaccata agatacgtct tgtgattgtg ctgacatttg tgtatgtgct tgttgggtgt
     5281 ttgtcgtttc tgctgcatct gcttgatgcg ccattgtaaa tgtagcgaag cccatcgttg
     5341 caatcgctgc tgctgttaat tttttcatgt ataaaacatc ctccattaaa gttaaagtta
     5401 gttttcaatt aaactgtact gcacatacta aaagaattag acaactgagt aaaggattta
     5461 attctcattt tccaactatt taatattccc gaaatgtttt actaaactca ttacattgtc
     5521 attacaaaat agccatacat tgatattaaa atgacatctc tcactgcatt cgtttaacct
     5581 tttataaatt ttcaaaacta acaactaatc attcgtccat gttcgcggtt caacgctaat
     5641 gtatgatagt aatcatccat caaatcatat caaccaaatt ccattatcaa tcgctattga
     5701 ttgtcattca actttctaat agtgatatgc ttctcaggct taaaaatcgt catatctttt
     5761 ctattaatta aatcatctgt gagctttaat gctactattt cattgctacc ataatactta
     5821 atatataacg ttcttgtagt taaatttatt acggtctgat acatcgtata gtgattgtca
     5881 gcatcatgcg gacgtacaat tccaatcggt atatttaccg catctaataa ataaaatgca
     5941 ttcattaaat ccatttcttt atcattgttt tgagcaatgt ttgctttcat aaatgccatt
     6001 ctcacaaagc gctcagttga agtaaatcca cctggcaatc caaatgtacc tgcttcattg
     6061 cctaaaggtt caatcgttac accttccaat aaatttgctg ttgctggata aggagaaata
     6121 ttgatatatt gccttaaatt actataatgc caatctaagt ctggatgatt tgttaagaca
     6181 ccaatagggt tatcttttat aaccacttca ccctctttaa atgaaacttc gactgattgt
     6241 ccagttgcat cggaaacatg ataatgcaat ggcggaactt caccgatatc atttaaatat
     6301 acagctacaa catgtatttg ggatgcttgt tgtttcatat cttcaatgct tgttgtatat
     6361 cccaaaatcc atgttacaat ttcattttgc gtaatattca tcgcgtccgc tttgtgtgtt
     6421 gatccatatg aactataacc tcggaaatat tgtgttgaaa tggcaacgcc atgttcatta
     6481 acaccatcac cataaataaa accttccata tctgttcctg tgccaataaa gccatattgc
     6541 gtttggcctg tcgtgccagt gcgagatgtc caacgataat ttctaggcgt cactgctggc
     6601 gaaccatcta atggataatc ataatccatc gtgcgtccaa gaagtacttg attatttaaa
     6661 gtttgtattg tgaatcctgt gcacattgtt ctcactcctc tgtaccttca tttactttaa
     6721 tcactttcaa ataaagctgt ttcacttaaa catactataa aaaatcaatc atacaagcaa
     6781 ttaattgata ttcattctca ataactgtgg tatgatatgt aaggaaatca tgacttatgt
     6841 gtgagtgaac gatcatctat acatccgttc acttcatctc atgactttct atatttaatt
     6901 tttacaagga gtgacatctg tgaataacac acaatcttca ccacgcagta atattattat
     6961 tgcgattatg ttgtctgcat taacatattg gttgtttgca caatcattta ttaatatagg
     7021 acctctcgtt ggtcaaacgt atcaaacctc tcctgccgtg ttaaatttat ctattagttt
     7081 aacttccttc gccacaggta tcttcatggt ggctgcaggt gatattgctg ataaaatagg
     7141 acaactgaga atgacataca tgggtctcat aatcagtatg tttgcatctc ttctattaat
     7201 tatatcggac atcactgcac tgctcatcat cggtagaatt ttacaaggtc tatcagcagc
     7261 tatcttgtta ccttcaacag ttggcgtttt aaataatcaa tttaaaggag aacatttaag
     7321 acgagcgatt agttatctaa tgattagtac tgttggtggc atcggcctag ctggtgttat
     7381 cggcggttta atcgccacaa atttcggatg gcaaacgaat ttcatcatta gtatagtcat
     7441 tgctttcatt gccatattgc ttctaaaagg cacacctgaa aaagtaagtc aacatagcca
     7501 tcgtcatcca ttcgattaca aaggtatgtc gattttcgct gttatgattg gtagctttac
     7561 attattgtta acacaaggat tcgaacaagg ttggtttagt acattttcat tcatttgtct
     7621 gagcattttt atcatcacta cgttgatatt catcatcatc gaacgtcgac atgaagtacc
     7681 ttttattgat ttttcagtat tacgcaaccg tccgttcatt ggtgcatttt taaataactt
     7741 tgttttaaat agcggtctag gcgtaacagt ggtctttttc atatatgctc aaacacacct
     7801 tggtttatca gctgcgcaat ctggacttgt tacattgcca tatgccattg tggcagttgc
     7861 gatgattcgt ttaggtgaaa aagcaacatt acgtttcggt ggcaaattga tgctcatcat
     7921 tggtccgttg ttccctgtca tcggcatcac tattattagc atgactcaat tatcggcatc
     7981 acaatatgtc attgcagtta tcattggttt cgtcatttgc gcaattggaa atggtttagt
     8041 cgcaacaccc ggccttacaa ttgcaatttt cagtatgcca aatgaaaaag ttggtttagc
     8101 tacaggatta tataaaatga gtggtacatt aggtggcgcc tttggtatag cactaagtac
     8161 tacagttttc agtatgttac aactaaacta tgcaccaagt gtagctgcaa ccgtaacatt
     8221 tatcgtcagc attgtattga tgatccttgg ctcattgtct gcatacatga tcattccaaa
     8281 aacagttaaa tcttaaatat aatagaagaa ttatgtttcg aaatatcttt atcactttaa
     8341 aatgatatac aagaaattca agaaaaataa gcgaagaacg tttttctctg ttcttcgctt
     8401 actctaatta tattcactat caattagaca aaatggccat tttcaaatat cacgcgttgt
     8461 ttctgacctt gaatatattt attataattc tctttttgaa aatcagttaa cattaattta
     8521 gatgtaccgt attttaacac tttttgcatt gtttctattc tcatttttct aaataaccat
     8581 ccatctttta acacaatacg attaacagca tcatatgata attctactgt ttctttaatt
     8641 tcaaatgtct tgaatgaaat aatcgtgcac attaaaaacg tatcaccaaa gtaataaaca
     8701 tctaaatcat cacgtttatg ttgtccaact aacaaacgac catattcgaa ctctttttct
     8761 ggatatttca attctaaaaa actaataatc tcttcttctt ttaatttgaa ttgcatttaa
     8821 aaacatcctc tcttaagttt taacaagcct taattaaaaa ttttttcaat cacatagttc
     8881 aatatacatc atttcgttat atttttt
//
LOCUS       DAPSKH010000083         8508 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPSKH010000083 DAPSKH010000000
VERSION     DAPSKH010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8508
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.083"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            66..1595
                     /gene="aur"
                     /locus_tag="RPH49_002427"
     CDS             66..1595
                     /gene="aur"
                     /locus_tag="RPH49_002427"
                     /EC_number="3.4.24.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloproteinase aureolysin"
                     /protein_id="HDY5125545.1"
                     /translation="MRKFSRYAFTSMATVTLLSSLTPAALASDTNHKPATSDINFEIT
                     QKSDAVKALKELPKSENVKNHYQDYSVTDVKTDKKGFTHYTLQPSVDGVHAPDKEVKV
                     HADKSGKVVLINGDTDAKKVKPTNKVTLSKDEAADKAFNAVKIDKNKAKNLQDDVIKE
                     NKVEIDGDSNKYIYNIELITVTPEISHWKVKIDTDTGAVVEKTNLVKEAAETGTGKGV
                     LGDTKNININSIDGGFSLEDLTHQGKLSAYNFNDQTGQATLITNEDENFVKDEQRAGV
                     DANYYAKQTYDYYKNTFGRESYDNHGSPIVSLTHVNHYGGQDNRNNAAWIGDKMIYGD
                     GDGRTFTNLSGANDVVAHELTHGVTQETANLEYKDQSGALNESFSDVFGYFVDDEDFL
                     MGEDVYTPGKEGDALRSMSNPEQFGQPSHMKDYVYTEKDNGGVHTNSGIPNKAAYNVI
                     QAIGKSKSEQIYYRALTEYLTSNSNFKDCKDALYQAAKDLYDEQTAEQVYEAWNEVGV
                     E"
     gene            1962..2411
                     /locus_tag="RPH49_002428"
     CDS             1962..2411
                     /locus_tag="RPH49_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDY5125546.1"
                     /translation="MKKSKRLEIVSTIVKKHKIYKKEQIISYIEEYFGVRYSATTIAK
                     DLKELNIYRVPIDCETWIYKAINNQTEQEMREKFRHYCEHEVLSSIINGSYIIVKTSP
                     GFAQGINYFIDQLNIEEILGTVSGNDTTLILTASNDMAEYVYAKLFK"
     gene            2414..2581
                     /locus_tag="RPH49_002429"
     CDS             2414..2581
                     /locus_tag="RPH49_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125547.1"
                     /translation="MYQMNNENLFRITCTQVSYQILTCVRVFLWKERIHSHSFDCIKN
                     FIQHVFMGIFE"
     gene            2758..3993
                     /gene="arcA"
                     /locus_tag="RPH49_002430"
     CDS             2758..3993
                     /gene="arcA"
                     /locus_tag="RPH49_002430"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDY5125548.1"
                     /translation="MTDGPIKVNSEIGALKTVLLKRPGKELENLVPDYLDGLLFDDIP
                     YLEVAQKEHDHFAQVLREEGVEVLYLEKLAAESIENPQVRSEFIDDVLAESKKTILGH
                     EEEIKALFATLSNQELVDKIMSGVRKEEINPKCTHLVEYMDDKYPFYLDPMPNLYFTR
                     DPQASIGHGITINRMFWRARRRESIFIQYIVKHHPRFKDANIPIWLDRDCPFNIEGGD
                     ELVLSKDVLAIGVSERTSAQAIEKLARRIFENPQATFKKVVAIEIPTSRTFMHLDTVF
                     TMIDYDKFTMHSAILKAEGNMNIFIIEYDDVNKDIAIKQSSHLKDTLEDVLGIDDIQF
                     IPTGNGDVIDGAREQWNDGSNTLCIRPGVVVTYDRNYVSNDLLRQKGIKVIEISGSEL
                     VRGRGGPRCMSQPLFREDI"
     gene            4026..5036
                     /gene="argF"
                     /locus_tag="RPH49_002431"
     CDS             4026..5036
                     /gene="argF"
                     /locus_tag="RPH49_002431"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDY5125549.1"
                     /translation="MTEIQKPYDLKGRSLLKESDFTKAEFEGLIDFAITLKEYKKNGI
                     KHHYLSGKNIALLFEKNSTRTRAAFTVASIDLGAHPEFLGKNDIQLGKKESVEDTAKV
                     LGRMFDGIEFRGFSQQAVEDLAKFSGVPVWNGLTDDWHPTQMLADFMTIKENFGYLEG
                     INLTYVGDGRNNIAHSLMVAGAMLGVNVRICTPKSLNPKEAYVDIAKEKASQYGGSVM
                     ITDNIAEAVENTDAIYTDVWVSMGEESEFEQRINLLKDYQVNQQMFDLTGKDSTIFLH
                     CLPAFHDTNTLYGQEIYEKNGLAEMEVTDQIFRSEHSKVFDQAENRMHTIKAVMAATL
                     GS"
     gene            5127..6557
                     /gene="arcD"
                     /locus_tag="RPH49_002432"
     CDS             5127..6557
                     /gene="arcD"
                     /locus_tag="RPH49_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDY5125550.1"
                     /translation="MNESGDNKLSKSSLIGLVIGSMIGGGAFNIMSDMGGKAGGLAII
                     IGWIITAIGMISLAFVFQNLTNERPELDGGIYSYAQAGFGDFVGFISAWGYWFSAFLG
                     NVAYATLLMSAVGNFFPIFKGGNTLSSIIVASILLWGVHFLILKGVETAAFINSIVTV
                     AKLIPILLVIICMIIAFNFDTFKTGFFGMTSEGVLPFSWASTMSQVKSTMLVTVWVFI
                     GIEGAVIFSSRAKNKKDVGSATVIGLISVLIIYFLLTVLAQGVILQNHISQLDSPSMA
                     QVLATIVGGWGSTLVNIGLIISVLGAWLGWTLLAGELPFIVAKDGLFPKWFAKENKNG
                     APVNALLITNILVQLFLISMLFKQSAYQFAFSLASSAILYPYMFSAFYQVKYTLEHRQ
                     QATTKQWTIGIIASIYAIWLIYAAGINYLLLTMLLYIPALLVYSIVQKNNQTRLIKSD
                     YILFMIIIVLAVIGLIKLLMGTINVF"
     gene            6574..7515
                     /gene="arcC"
                     /locus_tag="RPH49_002433"
     CDS             6574..7515
                     /gene="arcC"
                     /locus_tag="RPH49_002433"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDY5125551.1"
                     /translation="MKEKIVIALGGNAIQTKEATAEAQQTAIRRAMQNLKPLFDSPAR
                     IVISHGNGPQIGSLLIQQAKSNSDTTPAMPLDTCGAMSQGMIGYWLETEINRILTEMN
                     SDRTVGTIVTRVEVDKDDPRFNNPTKPIGPFYTKEEVEELQKEQPDSVFKEDAGRGYR
                     KVVASPLPQSILEHQLIRTLADGKNIVIACGGGGIPVIKKENTYEGVEAVIDKDFASE
                     KLATLIEADTLMILTNVENVFINFNEPNQQQIDDIDVATLKKYAAQGKFAEGSMLPKI
                     EAAIRFVESGENKKVIITNLEQAYEALIGNKGTHIHM"
     gene            7614..8318
                     /locus_tag="RPH49_002434"
     CDS             7614..8318
                     /locus_tag="RPH49_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDY5125552.1"
                     /translation="MTENFILGRNNKLEHELKALADYINIPYSILQPYQSECFVRHYT
                     KGQVIYFSPQESSNIYFLIEGNIIREHYNQNGDVYRYFNKEQVLFPISNLFHPKEVNE
                     LCTALTDCTVLGLPRELMAFLCKANDDIFLTLFALINDNEQQHMNYNMALTSKFAKDR
                     IIKLLCHLCQTVGYDQDEFYEIKQFLTIQLMSDMAGISRETAGHIIHELKDEKLVVKD
                     HKNWLVSKHLFNDVCV"
BASE COUNT         3114 a         1183 c         1640 g         2571 t
ORIGIN      
        1 tttctgaaaa attaaattaa tattttattt ataagctgtt tttaaaattt caggaggaat
       61 gaaatgtgag gaaattttca agatatgcat ttacaagtat ggcgacagta acgttgctga
      121 gctctttgac acctgcagca ctagcgagtg atacgaatca caaaccagca acttcagata
      181 ttaattttga aatcacacaa aagagtgatg cagttaaagc attaaaagag ttacctaaat
      241 ctgaaaatgt gaaaaatcat tatcaagatt actctgttac agatgtaaaa acagataaga
      301 aaggatttac gcattacacg ttacaaccga gtgtggatgg tgttcatgca cctgacaaag
      361 aagtgaaagt acacgcagac aaatcaggaa aagtcgtttt aatcaacggt gatactgacg
      421 caaagaaagt aaagccgaca aataaagtga cattaagcaa ggatgaagcg gctgacaaag
      481 catttaacgc agttaagatt gataaaaata aagctaaaaa cctccaagat gacgttatca
      541 aagaaaataa agtcgaaatc gacggtgaca gtaataaata catttacaat attgaattaa
      601 ttacagtaac accagaaatt tcacattgga aagttaaaat tgataccgac acaggagcag
      661 ttgttgaaaa aacgaactta gttaaagaag cggcagaaac tggtacaggt aaaggagtac
      721 tcggcgatac aaaaaatatc aatatcaata gtattgacgg tggatttagc ctagaagatt
      781 taacgcatca aggtaaatta tcagcataca attttaatga tcaaacaggt caagcaacat
      841 tgattactaa tgaagatgaa aacttcgtca aagatgagca acgtgctggt gtagatgcga
      901 attattatgc taaacaaaca tatgattact acaaaaatac atttggtcgt gagtcttacg
      961 ataaccatgg tagtccaatt gtctcattaa cacatgtaaa tcattatggt ggacaagata
     1021 acagaaataa cgctgcatgg attggagaca aaatgattta tggtgatggc gatggccgca
     1081 cgtttacaaa tttatcaggt gcaaatgacg tagtagcaca tgagttaaca catggcgtga
     1141 cacaagaaac ggcgaattta gagtataaag atcaatctgg tgcgttaaat gaaagctttt
     1201 cagatgtttt tggatacttt gtagatgatg aggatttctt gatgggtgaa gatgtttaca
     1261 caccaggaaa agagggagat gctttacgaa gcatgtcaaa cccagaacaa tttggtcaac
     1321 catctcatat gaaagactat gtatacactg aaaaagataa cggtggtgtg catacgaatt
     1381 ctggcattcc aaataaagca gcttataacg taattcaagc aatagggaaa tctaaatcag
     1441 aacaaattta ctaccgagca ttaacggaat acttaacaag taattcaaac ttcaaagatt
     1501 gtaaagatgc attataccaa gcggctaaag atttatatga cgagcaaaca gctgaacagg
     1561 tgtatgaagc atggaatgaa gtaggcgtgg agtaaaaata tataaacaag aagaagtaat
     1621 gttaaacact tataaataat taaattttaa atacagctta tatatggggt atacctacat
     1681 tgataattga ctttgtaggt ataccctctc tttgtaatta gatgagagga gtgtgagggt
     1741 tgtctgccga aagactactc ggcagtctaa aatcattaca agtagtagat atgtgataat
     1801 taaatgctga cttagaatac aaaattcatt ttaaaagttg tcacaaaaaa tttacatgta
     1861 tttttattat cttttgcaaa acaaagtgtt aaattataaa tgaaacatgc atgaatttat
     1921 tttttaatac aagaaacgta actaccaaag gagtttacaa tatgaagaaa agtaaacgat
     1981 tagaaattgt ttctacaata gttaaaaagc ataagattta taaaaaagaa caaatcattt
     2041 catatattga agaatatttt ggtgtaagat atagtgcaac aacaattgct aaagacttga
     2101 aagaacttaa tatatatcgt gtccctatcg attgtgaaac atggatttat aaagctatta
     2161 ataatcaaac agaacaagag atgagagaaa agtttagaca ctattgtgaa catgaagttc
     2221 taagttcaat catcaatggt tcatacatta tcgttaaaac ctcacctggt ttcgcccaag
     2281 gcataaacta ttttatcgat cagctaaata tagaagagat attaggtacg gtgagtggaa
     2341 atgacactac attaatctta actgcctcaa atgatatggc agaatacgta tatgcaaaat
     2401 tatttaaata gacatgtatc aaatgaataa tgaaaatttg tttcgtatca cgtgtactca
     2461 agttagttac caaatattaa cttgtgtacg cgttttttta tggaaagaaa gaattcatag
     2521 tcattcattt gactgtataa aaaactttat acaacatgtt tttatgggta tttttgaata
     2581 aaaaatgtat atttcgaccc aaaacacctt tatttatgta taaaaatcca ttattatgta
     2641 ttgtataaca aaaagatatg aaattttcga ctttctttat gtgaatataa tcacatgtaa
     2701 gcgtttgaag attgtctata ctctaaatga attcaaagat aaaaggagga aatagacatg
     2761 acagatggtc caattaaagt aaatagcgaa attggagctt taaaaactgt gttacttaag
     2821 cgtcctggaa aagaattaga aaatttagta cctgattatt tagatggatt actatttgat
     2881 gatattccat atttagaagt agctcaaaaa gagcatgacc attttgcaca ggtgctaaga
     2941 gaagagggtg ttgaagtact ttaccttgag aagttagcag ctgaaagtat tgaaaatcct
     3001 caagtaagaa gtgaatttat tgatgatgta ttagcagagt ctaaaaaaac aatattaggt
     3061 catgaagaag aaattaaggc attatttgcg acactttcta atcaagaact tgtagataaa
     3121 ataatgtcag gggtacgtaa ggaagaaatt aatccgaaat gtacacatct agtagagtat
     3181 atggatgata agtatccatt ctatttagat ccaatgccaa acctttattt tactagagat
     3241 ccacaagcct caataggaca cggtataaca atcaatcgga tgttctggag agcacgacga
     3301 cgagaatcaa tatttattca atatattgta aagcatcatc ctagatttaa agatgcgaat
     3361 attccaatct ggttagatcg agattgccca ttcaatattg aaggcggcga tgaacttgtt
     3421 ttatctaaag atgtcttggc tataggcgtt tcagaacgta catctgcaca agctattgaa
     3481 aagttagcgc gacgtatttt tgaaaatccg caggcgacgt ttaaaaaagt agtagcaatt
     3541 gaaattccaa ctagtcgaac ttttatgcac ttagatacag tatttacaat gatagattat
     3601 gacaaattta caatgcattc agccatttta aaggcagaag gcaatatgaa tatatttatt
     3661 attgaatatg atgacgtaaa taaagatatt gccatcaaac aatctagtca tttaaaagat
     3721 actttagaag acgtactagg tatagatgat atccaattca ttccaacagg aaatggtgat
     3781 gtcattgatg gtgctagaga gcaatggaat gatggctcaa atacattatg tataagacca
     3841 ggcgttgtag tgacttacga tagaaactat gtatcgaatg atttattgag acaaaaaggc
     3901 attaaagtca ttgaaatatc tggtagcgag ttggtacgtg gacgtggggg tcctagatgt
     3961 atgagtcaac cactattcag agaagacatt taacgtaata aattatagaa acgagggtga
     4021 aaataatgac agaaattcaa aaaccgtatg atttaaaagg cagatcatta ttaaaagaaa
     4081 gtgattttac caaagcagaa ttcgaaggac ttattgattt tgcaattaca ttaaaagagt
     4141 ataagaaaaa cggtattaag catcactact tatctggaaa aaatattgca ctactattcg
     4201 aaaagaattc gacgagaacg cgtgcagcgt ttacagttgc gtctattgat ttaggtgcgc
     4261 atccagaatt tttagggaaa aatgatattc aattaggcaa aaaagaatct gtagaggata
     4321 ctgcgaaagt attaggtaga atgttcgatg gtattgaatt ccgtggtttt tcacaacaag
     4381 ctgttgaaga tttagcgaag ttctctggtg taccggtgtg gaatggatta acagacgatt
     4441 ggcatcctac acaaatgtta gctgatttta tgacaataaa agagaatttt ggatatctag
     4501 aaggaataaa cttaacttac gttggagatg gacgtaataa tattgcgcat tcattaatgg
     4561 tagcaggtgc tatgttaggt gttaatgtaa gaatttgtac acctaaatca ttaaatccaa
     4621 aagaggcata tgttgatatt gcaaaagaaa aagcgagtca atatggtggt tcagtcatga
     4681 ttacggataa tattgcagaa gcagttgaaa atacagatgc tatatataca gatgtttggg
     4741 tatcgatggg tgaagaaagt gaatttgaac aacgtattaa tttattaaaa gactatcaag
     4801 tgaatcaaca gatgtttgat ttaacaggta aagattcaac gatattctta cattgtttac
     4861 cagcattcca tgatacaaat acactttatg gacaagaaat ttatgaaaaa aatggattag
     4921 ctgaaatgga agttacagac caaatcttta gaagtgaaca ttcaaaagtg tttgatcaag
     4981 ctgaaaatag aatgcataca attaaggcag taatggcagc aacattgggg agttaatcac
     5041 taaatggaat gatatgaata tgatgtgtct gatgatataa gtgtcatgta cagacacctc
     5101 atattggtat taaaggagaa atgaatatga acgaatcagg agataacaaa ctcagtaaat
     5161 cttctttaat tggactagtt ataggatcca tgattggtgg cggtgcgttc aatataatgt
     5221 ctgatatggg cggtaaagcc ggtggattag ccattattat tggttggatt attacagcta
     5281 taggaatgat ttcattagcg ttcgtatttc aaaatttaac caatgaacgg ccggagctag
     5341 acggtggtat ttatagttat gctcaagcag gatttggcga ttttgtaggc tttatcagtg
     5401 cttggggata ttggttctca gcgtttttag gcaatgttgc ctatgcaaca ctattgatgt
     5461 cagcagtagg taactttttc ccgattttta aaggaggcaa cacattatca agtattattg
     5521 tcgcatctat attactttgg ggtgtgcatt tcctaatttt aaaaggtgtt gaaacagcag
     5581 cctttatcaa tagtattgtt actgttgcaa agttaatacc gattttactt gtaatcatat
     5641 gcatgataat tgcattcaat tttgacactt ttaaaacagg ctttttcggt atgacgtcag
     5701 agggtgtatt gccatttagt tgggcgagca caatgagcca agttaaaagt acgatgctag
     5761 tgacagtttg ggtgtttatc ggtatcgaag gtgcagtaat tttttctagt agagctaaaa
     5821 ataaaaaaga tgtaggtagt gccacggtta taggacttat atcagtttta attatctatt
     5881 tcttattaac tgtattagct caaggcgtga ttttgcaaaa tcatatttct caattagatt
     5941 cgccaagtat ggcacaggtg cttgcaacta ttgtaggtgg ttggggatct acacttgtaa
     6001 atattggttt aattatttcg gtactaggtg catggttagg atggacattg cttgctggtg
     6061 aattaccttt cattgttgca aaagatggat tatttccaaa atggtttgct aaagaaaata
     6121 aaaatggagc acctgtaaat gcactgctta ttaccaatat attagtacaa ttatttttaa
     6181 taagtatgct atttaaacag agtgcgtatc aatttgcatt ttcactagca tcaagtgcta
     6241 ttttataccc ttacatgttc agtgcatttt accaagttaa atacacttta gagcatcgac
     6301 agcaagcaac tactaaacaa tggacgattg gtatcatagc ctcaatttat gctatatggc
     6361 ttatatatgc agcaggtatc aattacttat tattgacgat gttactttat attccagctc
     6421 ttcttgttta ttcaatcgtt caaaagaata atcagacacg tttgattaaa tcagactata
     6481 tcctttttat gattattatc gtacttgcag ttatcgggtt aattaagtta ttgatgggaa
     6541 cgataaatgt tttttaaaag gagcgacaaa aatatgaaag agaaaattgt cattgcatta
     6601 ggcggtaatg cgatacagac aaaagaagca acagctgaag cacaacaaac agctattaga
     6661 cgtgcgatgc aaaaccttaa acctttattt gattcaccag cgcgtattgt catttcacat
     6721 ggtaatggcc cacaaattgg aagtttatta atccaacaag ctaaatcgaa cagtgacaca
     6781 acgccggcaa tgccattgga tacttgtggt gcaatgtcac agggtatgat aggctattgg
     6841 ttggaaactg aaatcaatcg cattttaact gaaatgaata gtgatagaac tgtaggcaca
     6901 atcgttacac gtgtggaagt agataaagat gatccacgat tcaataaccc aaccaaacca
     6961 attggtcctt tttatacgaa agaagaagtt gaagaattac aaaaagaaca gccagactca
     7021 gtctttaaag aagatgcagg acgtggttat agaaaagttg ttgcgtcacc actacctcaa
     7081 tctatactag aacaccagtt aattcgaact ttagcagacg gtaaaaatat tgtcattgca
     7141 tgcggtggtg gcggtattcc agttataaaa aaagaaaata cctatgaagg tgttgaagcg
     7201 gttatagata aagattttgc tagtgagaaa ttagcaacgc tgattgaagc agatacctta
     7261 atgattctta cgaatgtaga aaatgtattt attaacttta atgaacctaa tcaacaacaa
     7321 atcgatgata ttgatgtagc aacactgaaa aaatacgcgg cacaaggtaa gtttgcggaa
     7381 ggatcgatgt tgccaaaaat agaagctgcg atacgatttg ttgaaagtgg ggaaaacaaa
     7441 aaagttatca ttaccaattt agagcaggca tacgaagctt tgattggtaa taaaggtaca
     7501 cacattcaca tgtagcactt tatcacgcga caaaacatta aatatgtttc tccgttgatt
     7561 caaatgaaaa agttgtctgc tgacactttg caaggtttga aggagtttaa cttatgacag
     7621 aaaactttat tttgggtaga aataataaat tagaacatga actaaaggca ttagcagatt
     7681 acattaatat cccatatagt atattacaac catatcaaag tgaatgtttt gtcagacatt
     7741 atacgaaagg ccaagttatt tatttttcgc cacaagaaag tagcaatatt tactttttaa
     7801 ttgaaggtaa cattattaga gaacattaca atcaaaatgg agatgtatat cgttatttta
     7861 ataaagagca agtattattt ccaatcagta acttatttca tccgaaagag gttaacgaat
     7921 tgtgtacagc actaaccgat tgtacagttc ttggattgcc tagagaattg atggcctttt
     7981 tgtgcaaagc taatgatgat atatttttga cactttttgc attaataaat gataatgagc
     8041 agcaacacat gaactataac atggcattaa caagtaaatt tgctaaagat cgaattatca
     8101 aattgttatg ccatctatgt cagacagtag gatacgatca agatgaattt tatgaaatca
     8161 aacagttttt aactattcaa ctcatgagtg atatggctgg gatttcccgg gaaacagctg
     8221 gtcatattat tcatgaactt aaagatgaaa aacttgttgt taaagatcat aaaaattggt
     8281 tagtaagcaa acatttattc aatgatgtat gtgtttaata tacaatgtaa aatgaataag
     8341 ttgaacatga ggtctaacgt acatttatac gttaggcctt ttttgctagc atgatgatta
     8401 atttaatatg ttagttaaat ttgattgttg aaattacagt aaaatttaag gtgatgaaaa
     8461 atttagaact tctaagtttt tgaaaagtaa aacatttgca atagtgta
//
LOCUS       DAPSKH010000084         8466 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPSKH010000084 DAPSKH010000000
VERSION     DAPSKH010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8466
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.084"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..315
                     /locus_tag="RPH49_002435"
     CDS             <1..315
                     /locus_tag="RPH49_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125553.1"
                     /translation="TLEKDIDNLQKENKELKDKKEKLQQEKEKLADKQKDLEKEVKDL
                     KPSKEDNKDDKKDEDKNKDKDKEASQDKQSKDQTKSSDKDNHKKPTSTDKDQKANDKH
                     QS"
     gene            453..752
                     /locus_tag="RPH49_002436"
     CDS             453..752
                     /locus_tag="RPH49_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125554.1"
                     /translation="MHEQDFRILEGQDITLPELGRELENITGRTIADSTGEIKRVIAH
                     LPNFESDTDTFVATYRLNHQQDFIDATFTALKSDRARLKEVPVHVELISYISKSK"
     gene            832..1374
                     /locus_tag="RPH49_002437"
     CDS             832..1374
                     /locus_tag="RPH49_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125555.1"
                     /translation="MIYCETERLILRDWHEDDLLPFQKMNANYDVRKYFPSLLSYRRS
                     ELDMRTMDAVIKDYGIGLFAVEDKESHQWIGFIGLNYIPETSDYPFKELPLYEIGWRL
                     LPEFWGKGLATEGAKVALKLAEQHQIYDVYSFTAEANKASQRVMEKIGMTVYDHFELP
                     NLSKYHLLKRQVRYYINLRK"
     gene            complement(1470..2036)
                     /locus_tag="RPH49_002438"
     CDS             complement(1470..2036)
                     /locus_tag="RPH49_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDY5125556.1"
                     /translation="MKRIAVYCGASKGHDPSYVQKAYDLGKYFAEQGYELVFGAGSIG
                     IMGAIQDGVLDHGGKAIGVMPKMLDEHEITSQRLTELILVDSMHERKNKMAELADAFV
                     MAPGGAGSLEEFFEMYSWAQIGIHEKPIAIYNINGFFNPLQTMIDHMIEEGFIDPKYR
                     ALAPLCDTKESLIESILNFKPLGTRSYD"
     gene            complement(2038..2496)
                     /locus_tag="RPH49_002439"
     CDS             complement(2038..2496)
                     /locus_tag="RPH49_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDY5125557.1"
                     /translation="MTHIIIDGDACPVVDSIIDLTTETGIFVTIIRSFSHFSNQLYPP
                     HVSTLYVDDGPDAVDYKIVQLSTKDDIVVTQDYGLASLLVDKVLIVMHHNGKIYNSKN
                     IQQLLDKRYMNAQIRKQGGRHKGPPPFTKQDQKVFEQSLLKVIHRIKELD"
     gene            complement(2499..3182)
                     /locus_tag="RPH49_002440"
     CDS             complement(2499..3182)
                     /locus_tag="RPH49_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125558.1"
                     /translation="MDKKKVIKFMINVLPIVLVPLIVERKRIKQHPDVQKVTDATSKV
                     ASKTSAAISNTASDVKEYVGDKKQDFENKRELKKFAREHDPAYIEKKGEKLAKQNRKD
                     ADKMNKILQKNIEKRHKEEQKAREKNEIQRVKDMKKSQKYEEKAGLTPNKLDEKTEKK
                     GDKLAEKNRKEIAKMNKKLQKNIEKRHKEEQKRQQEADKARIKSFKKYKDYVAKSASQ
                     QNKENNTEA"
     gene            complement(3354..4229)
                     /locus_tag="RPH49_002441"
     CDS             complement(3354..4229)
                     /locus_tag="RPH49_002441"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDY5125559.1"
                     /translation="MFIIELIKGIILGVVEGLTEFAPVSSTGHMILVDDMWLKSSEFL
                     GSQSAFTFKIVIQLGSVFAAAWVFRERFLEILHIGKHKHVEGENDQQRRSKPRRLNLL
                     HVLVGMVPAGILGLLFDDFIEEHLFSVPTVMIGLFVGAIYMIIADKYSAKVKNPQTVD
                     QINYFQAFVIGISQAVAMWPGFSRSGSTISTGVLMKLNHKAASDFTFIMAVPIMLAAS
                     GLSLLKHYQDIQIADIPFYILGFLAAFTVGLIAIKTFLHLINKIKLIPFAIYRIVLVI
                     FIAILYFGFGIGKGI"
     gene            4448..6079
                     /locus_tag="RPH49_002442"
     CDS             4448..6079
                     /locus_tag="RPH49_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HDY5125560.1"
                     /translation="MKKLTTILFQYKIFPVLMFMVSTGLGILVITQNILIADFLAKII
                     RHQFQGLWIVLFILLGVLLLRATVQFLNQWLGDTLAFKVKHMLRQRVIYKNNGHPIGE
                     QMTILTENIDGLAPFYKSYLPQVFKSMMVPLIIIIAMFFIHFNTALIMLITAPFIPLF
                     YIIFGLKTRDESKDQMTYLNQFSQRFLNIAKGLVTLKLFNRTEQTEKHIYDDSTQFRT
                     LTMRILRSAFLSGLMLEFISMLGIGLVALEATLSLVVFHNIDFKTAAIAIILAPEFYN
                     AIKDLGQAFHTGKQSEGASDVVFEFLEQPNNNNEFLLKYEENQKPFIQLTDISFRYDD
                     SDRLVLNDLNLEIFKGDQIALVGPSGAGKSTLTHLIAGVYQPTIGTISTNKRDLNIGI
                     LSQQPYIFSASIKENITMFKDIENNTIEEVLDEVGLLDKVQSFTQGINTIIGEGGEML
                     SGGQMRRIELCRLLVMKPDLVIFDEPATGLDIQTEHMIQNVLFQHFKDTTMIVIAHRD
                     NTIRHLQRRLYIENGRLIADDRNISVNITENGDDL"
     gene            6076..7749
                     /locus_tag="RPH49_002443"
     CDS             6076..7749
                     /locus_tag="RPH49_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding/permease
                     protein"
                     /protein_id="HDY5125561.1"
                     /translation="MKTRLKFQVDKDLLLAIVVGVCGSLVALAMFFLSGYMVTQSALG
                     APLYALMILVVTVKLFGFLRAITRYVERLISHKATFTMLRDIRVQFFGKLVNVIPNVY
                     RKLSSSDLISRMISRVEALQNIYLRVYYPPVVIGLTALVTVIVLAFISISHALLIMVS
                     MLFTLLVVPWLSSKKARTLKKHAANEQARFLNHFYDYKAGMDELRRFNQINHYRDNLM
                     AKLNHFDKLQLKEQRFLTIYDFILNIIAMLSIFGSLVLGLIQINAGQLNIIYMTSIVL
                     MVLTLFEQAVPMTNVAYYKADTDQALHDINEVISVPSTNGKNRLNDKYDATNIYEVKD
                     ASFKYWNQQTYVLSDINFNVNRGEKIAIVGPSGSGKSTLLQIMAGLYQLDSGSIRFEN
                     MDMFEIDDKDKFESLNVLLQSQQLFDGTIRQNLFTDEKDEAVQAIFKQLDLEHLALER
                     QIDLDGHTLSGGEIQRLAIARMLLKDTVSTWILDEPTTALDKQNSLKVMDLIEAHAET
                     LIVATHDLTLLSRFETIIVMINGKIVEKGNYQQLLANQGALWNMIQYNA"
     gene            complement(7876..8319)
                     /gene="mgrA"
                     /locus_tag="RPH49_002444"
     CDS             complement(7876..8319)
                     /gene="mgrA"
                     /locus_tag="RPH49_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MgrA"
                     /protein_id="HDY5125562.1"
                     /translation="MSDQHNLKEQLCFSLYNAQRQVNRYYSNKVFKKYNLTYPQFLVL
                     TILWDESPVNVKKVVTELALDTGTVSPLLKRMEQVDLIKRERSEVDQREVFIHLTDKS
                     ETIRPELSNASDKVASASSLSQDEVKELNRLLGKVIHAFDETKEK"
BASE COUNT         2839 a         1268 c         1437 g         2922 t
ORIGIN      
        1 actctggaaa aggacatcga taatttacaa aaagaaaata aagaattaaa agataaaaaa
       61 gaaaagcttc aacaagaaaa agaaaaatta gcagataagc aaaaagacct tgaaaaagaa
      121 gtgaaagatt taaaaccttc aaaagaagat aacaaggatg ataaaaaaga cgaagacaaa
      181 aataaagata aagataaaga ggcatcacaa gataagcaat caaaagatca aactaagtca
      241 tcggataaag ataatcacaa aaagcctaca tcaacagata aagatcaaaa agctaatgac
      301 aaacaccaat cataattgaa ttgctttctt gttatagatg aaaggtacag cgttttaaac
      361 cttattttaa gggtatgtat taattaaaat gtggtcatga ttgaaacaga atgtaaaaat
      421 agacaacgta attaataaag gagagaaacg gcatgcatga acaagatttt agaattttag
      481 agggtcaaga tattactttg ccagaattag gtagagaatt agaaaatatt acaggacgca
      541 cgattgctga ttctactggc gaaattaagc gtgtaattgc acatttacca aactttgagt
      601 ccgatacaga tacttttgtt gctacatatc gtttaaacca tcaacaagat tttatagatg
      661 ctacttttac tgcgctgaaa tcagatagag cacgtttaaa agaagtgcca gttcatgttg
      721 aacttataag ttatatttct aaatcaaaat aaactgctat ctaaaacgca aagttgatca
      781 aaatatcgat tttgtgtttt ttattgagaa attatatagg agtgtcaatc gatgatttat
      841 tgtgaaacag agcgtttaat attaagagac tggcatgaag atgatctgtt accttttcaa
      901 aaaatgaatg cgaattatga cgtacgtaaa tattttccaa gtttattgag ttatcgtcgt
      961 tcagaattag atatgagaac tatggatgcg gttattaaag attatggcat tggattattt
     1021 gctgtagaag ataaagagtc ccatcaatgg ataggcttta taggtttgaa ttatattcca
     1081 gaaacaagcg attatccatt taaagaatta ccgctttatg aaataggttg gcgcttgttg
     1141 ccagaatttt ggggaaaagg attagcaact gaaggcgcaa aggtagcgtt gaagttagca
     1201 gaacaacatc aaatatacga tgtctatagt tttacagcag aagcaaataa agcttcacaa
     1261 cgtgtaatgg aaaaaattgg catgacagtg tatgatcatt tcgaattacc caatctaagt
     1321 aagtatcatt tattaaaaag gcaagtgcgc tattacatta atcttcgaaa gtgaaaaatt
     1381 tatacataag cgtaacaaac acccctaata ttgtttagct gatgataaca atattagggg
     1441 tgtttgttta ttttttaacc ttagaatgat taatcgtatg aacgagtacc tagaggtttg
     1501 aaattcaata tagattctat taatgattcc ttagtgtcac ataacggtgc aagtgcacga
     1561 tacttaggat caataaaacc ttcctcaatc atatggtcaa tcattgtttg tagtggattg
     1621 aaaaagccat taatattata aatggcaata ggcttttcat ggataccaat ttgagcccaa
     1681 ctatacattt cgaaaaattc ttctagtgaa cctgcgccgc cgggagccat gacaaatgca
     1741 tctgcaagtt ctgccatttt atttttacgt tcatgcatag aatcaactag aattaattca
     1801 gttaaacgtt ggcttgtgat ttcatgttca tctaacattt taggcatgac gccaatagct
     1861 ttgccgccat gatctaatac accatcttga atggcaccca taataccaat tgaccctgca
     1921 ccaaatacta attcataacc ttgttcagca aaatatttac ctaaatcgta tgctttttgt
     1981 acatatgaag ggtcatgacc tttgcttgca ccacaataaa ctgcgattcg tttcatgtta
     2041 atccagctcc ttaattcgat gaatgacttt taatagtgat tgttcaaaca ctttttgatc
     2101 ttgctttgta aaaggtgggg gacctttgtg gcgaccacct tgttttctaa tttgtgcatt
     2161 catatatcgt ttatctaata gttgttgaat atttttggaa ttgtatatct tcccattatg
     2221 atgcatgaca attaagactt tgtcgactaa taaacttgcg agtccataat cttgagtgac
     2281 tacgatatca tctttcgttg ataattgaac aattttgtaa tcaactgcat ctggtccatc
     2341 atcaacatat aatgttgata catgcggggg atataattgg ttcgaaaaat ggctgaagct
     2401 ccgaataatt gtcacaaaaa tgcctgtctc agttgttaaa tctataatag aatcaacaac
     2461 aggacaagca tctccatcaa taataatatg tgtcacaatt atgcctcagt attgttttct
     2521 ttattttgtt gagaggcgct tttggcaaca taatctttat attttttaaa tgacttgatg
     2581 cgtgctttat cagcttcttg ttggcgtttt tgttcttctt tgtgtcgttt ttcaatattt
     2641 ttttgtaact ttttattcat tttagcgatt tctttgcgat ttttttcagc tagtttatcg
     2701 ccttttttct cagttttctc atctaattta ttaggtgtta agcctgcttt ttcttcgtat
     2761 ttttgtgatt ttttcatatc tttaacacgt tgtatttcat tcttttcgcg ggctttttgc
     2821 tcttctttat gacgcttttc gatatttttt tgaagtattt tattcatttt atcagcgtct
     2881 ttacgatttt gtttagctaa tttttcgcct tttttctcaa tataggcagg atcatgttct
     2941 ctagcaaact ttttaagttc acgcttattt tcaaaatctt gttttttatc gccgacatat
     3001 tctttaacat cactcgctgt gttactgatt gctgcagatg tttttgaagc aactttactt
     3061 gtagcatctg taactttttg tacgtccgga tgttgtttga tacgtttacg ttcaacaatt
     3121 aacggtacca atacaattgg taatacatta atcataaatt tgatgacttt tttcttatcc
     3181 atagatcttg cctccataat tactttatta attttacata ccctatgata catcaatata
     3241 aacgatgata gtagtgaatc actattaagt atttcagatg ttttttaaaa gaagacaata
     3301 aaaactgcca atcaagtggt tccttaattg acagtctata ttttaaaagg aaattaaata
     3361 cctttaccaa tgccaaatcc gaagtaaagt atagcaataa agattactaa tacaattctg
     3421 taaatggcaa atggaattag tttgattttg ttaattagat gcaagaatgt tttgattgca
     3481 attagtccaa cagtaaatgc agctaaaaag cctaaaatat aaaaaggtat atcagcaatc
     3541 tgaatatctt gataatgttt taataaagat aaaccactag ctgctaacat aattggaaca
     3601 gccataataa atgtgaagtc tgatgcagct ttatgattta atttcattaa taccccagtt
     3661 gaaattgttg agcctgaacg gctgaaacca ggccacatag ctactgcttg agagatacca
     3721 attacaaacg cttggaaata attgatttga tctactgttt gtgggttttt aactttagct
     3781 gagtatttat cagcaataat catatagata gcacctacga ataagccaat cataacagtt
     3841 ggcacactaa ataaatgttc ttcgatgaaa tcatcaaata gtaagcctaa aatacctgct
     3901 ggcaccatac ccactaatac atgtaataaa tttaaacgtc ttggctttga acgtctttgt
     3961 tgatcgtttt ctccttcaac atgtttgtgt ttaccaatat gtaaaatctc taagaagcgt
     4021 tcgcggaata cccatgctgc tgcaaagacg gatcctaatt ggatgacgat tttaaatgta
     4081 aatgctgatt gagaacctaa aaattcagat gattttaacc acatatcatc aactagaatc
     4141 atatgtccag tagaggaaac aggtgcaaat tctgttaatc cttcgacgac ccctaagata
     4201 atacctttta ttaattcaat gataaacata atgtacccac tttcattact caatttaatt
     4261 tatttaaata tcaaaattac catatcatga tagcatattc atttaaagac atgctagtta
     4321 tagttataat actagactaa agatgtatat attcattttc ttttacatgt aaaactacaa
     4381 tattttattg agctatttaa tttgatttta aggaaaacct tttataatag gtttaggtga
     4441 tataattgtg aaaaaattaa caacaatact gtttcaatat aaaatttttc cggtactcat
     4501 gttcatggtc agtactggtc tcggcatact cgttataacg caaaatattt taatagcaga
     4561 ttttttagct aaaattataa gacatcaatt tcaaggttta tggattgtat tatttatttt
     4621 attaggtgtt ttacttttaa gagcaactgt gcaatttcta aatcaatggt taggtgatac
     4681 attagcattt aaagttaagc atatgcttag acagcgggtt atttataaaa ataatggtca
     4741 tccaatcggt gaacaaatga ctatactcac agaaaacatt gatggtctag caccttttta
     4801 taagagttat ttgcctcaag tgttcaaatc aatgatggtt ccgctcatca taatcattgc
     4861 aatgtttttc atccatttca ataccgcatt aattatgtta ataactgcac catttattcc
     4921 tttgttttat attattttcg gtttgaaaac gcgagatgag tcaaaagatc aaatgactta
     4981 tttgaatcaa tttagtcaac ggtttttaaa tattgctaaa ggtttagtga cgttaaagct
     5041 atttaatcgt acagagcaaa cagagaagca tatttacgac gatagtactc agtttagaac
     5101 tttaacaatg cgcattttac gcagtgcttt tttatcggga ttaatgctcg aatttataag
     5161 tatgttaggt attggattgg ttgcattgga agcaacgcta agcttagtag tatttcataa
     5221 tattgatttt aaaactgcgg caattgcgat tattttagcg cctgaatttt ataatgcaat
     5281 taaggactta gggcaagcgt tccatactgg aaaacaaagt gaaggtgcca gtgacgttgt
     5341 gtttgagttt ttagaacaac cgaacaataa taatgaattt ctattaaagt atgaggaaaa
     5401 tcaaaagcca tttattcagt taacagacat atcatttcga tatgatgatt ctgatagatt
     5461 ggtattaaat gatttaaatt tggaaatatt taaaggtgat caaattgcac ttgtaggtcc
     5521 aagcggggca ggtaaatcca ctttgacaca tcttattgca ggtgtttatc agccaacaat
     5581 aggtactata agtacaaaca agcgtgattt aaatatagga atacttagtc aacagccata
     5641 tattttcagt gcttctataa aagagaatat tacgatgttt aaagatatag aaaataatac
     5701 tattgaagaa gtgctagacg aagtaggttt attagacaaa gtgcaatctt tcacacaagg
     5761 cattaacaca ataataggtg aaggaggcga aatgttatct ggtggacaga tgagacgcat
     5821 agaactttgc cgtcttttag ttatgaagcc agatctcgtt atatttgatg agcctgcaac
     5881 tggtttagat attcaaacag aacacatgat tcagaacgtt ctgtttcaac attttaaaga
     5941 tacaacgatg attgtcattg cacatagaga taatacaatt cgccatttac aacgacgttt
     6001 gtatatagaa aatggaagac tgattgctga tgatcgcaat atttcagtaa atataacaga
     6061 aaatggtgat gacttatgaa aacacgacta aaatttcaag tagataagga tttattgtta
     6121 gctatagttg ttggtgtttg tggaagttta gttgcgctcg ccatgttttt cttaagtggt
     6181 tatatggtga cacaaagtgc acttggtgcg ccactatacg ctctgatgat tttagtcgta
     6241 acagtaaaat tgtttgggtt tttaagagct attactcgat acgtagagcg tcttatttct
     6301 cataaagcta catttacaat gctacgtgat attcgggtac agtttttcgg taaattagta
     6361 aatgtcattc ctaatgttta ccgtaaactg agttctagtg atttaatttc acgtatgatt
     6421 agtcgtgttg aggcattaca aaatatatat ttacgtgttt attatccgcc agtcgttatc
     6481 ggtttgacag cgctagttac agtaatagtt ttggcgttca tttcaatcag ccatgcgcta
     6541 ttgattatgg ttagcatgtt gtttacttta ctcgttgttc cttggttaag ctcaaaaaaa
     6601 gcacgtactt taaagaaaca tgcagctaat gaacaggccc gttttttaaa tcatttttat
     6661 gattataaag ctggtatgga tgaactacgt cgatttaatc aaattaatca ttatcgagat
     6721 aatttgatgg ctaaattaaa tcattttgat aaattacaac ttaaagagca acgcttttta
     6781 acgatttatg attttatatt aaatattatt gctatgcttt cgatttttgg tagtttagtt
     6841 ctaggattaa ttcaaattaa tgcaggccaa ctaaatatta tttatatgac gagtatagtt
     6901 ttaatggtct taactttatt tgaacaagct gtaccaatga caaatgtcgc gtattataaa
     6961 gcggatactg accaagcatt gcatgatatt aatgaagtga tatctgtacc ttctactaat
     7021 ggaaaaaacc gtcttaatga taagtatgat gcaacgaaca tttatgaagt taaggacgct
     7081 agttttaagt attggaacca gcaaacgtat gtgttgtcgg atattaattt taatgttaat
     7141 agaggcgaaa agattgcgat tgtgggtcct tctggttcag gaaaaagtac attactacaa
     7201 attatggctg ggttatatca attagatagt ggctctattc gtttcgaaaa tatggatatg
     7261 tttgaaatag atgacaaaga taagtttgaa tcgttaaatg tcttgctaca atctcaacaa
     7321 ttatttgatg gtacaatacg tcaaaattta tttaccgatg aaaaagatga agcggtgcaa
     7381 gcaatattta agcaattaga tttagaacat ttggcactag aacgtcaaat tgacttagat
     7441 ggtcatacat tatctggcgg agaaattcag cgtttagcga ttgcgaggat gttattaaaa
     7501 gatactgtat caacatggat tttagatgaa ccaacaactg cattagataa acaaaatagt
     7561 ttaaaagtta tggatttaat tgaagcacat gcagaaacat taattgttgc tacacacgat
     7621 ttaactttat tgtcacgttt cgagaccatc attgtgatga taaatggtaa aatagttgaa
     7681 aagggaaact atcaacaatt actcgctaat caaggtgctt tatggaatat gattcaatat
     7741 aatgcataaa aaaactgctt gataggctaa gaaacctttc aagcagtttt ttaactaaca
     7801 agcttacgcg tgctaattgt ttttctattc ttaataaatt ctaaacatta ctttaattgt
     7861 catgacaaaa gttaattatt tttcctttgt ttcatcaaat gcatgaatga ctttacctaa
     7921 taagcgatta agttctttaa cttcatcttg agataaagaa gaagctgaag cgactttgtc
     7981 agatgcatta cttaattctg gtctaatagt ttcacttttg tcagtcaagt gaataaatac
     8041 ttcacgttga tcgacttcgg aacgttcacg cttaattaag tctacttgtt ccattcgttt
     8101 taataatggt gatactgtac cagtatcgag tgctaattca gttacgactt tcttgacgtt
     8161 tacaggagat tcatcccata aaattgttaa gacaagaaat tgtgggtatg ttagattgta
     8221 cttcttaaaa actttgttag agtagtagcg attaacttgt ctttgagcat tgtacaaact
     8281 aaagcatagc tgttctttta aattatgttg atcagacatt aaagttctcc tccagacata
     8341 ctatccgttt ttttctcttt tcggattggt aatcattaaa aagttgattg tttattaatt
     8401 cacaactttc tttgattcaa tgccatgcta aaattaaagt atgtttaaag tttagaagat
     8461 attttt
//
LOCUS       DAPSKH010000085         8465 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPSKH010000085 DAPSKH010000000
VERSION     DAPSKH010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8465)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8465)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8465
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.085"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..850)
                     /locus_tag="RPH49_002445"
     CDS             complement(<1..850)
                     /locus_tag="RPH49_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exonuclease"
                     /protein_id="HDY5125563.1"
                     /translation="MPNKILLVDGMALLFRHFYATSLHKQFMYNSQGVPTNGIQGFVR
                     HIFSAIHEIRPTHVAVCWDMGQSTFRNDMFDGYKQNRSAPPEELIPQFDYVKEISEQF
                     GFVNIGVKNYEADDVIGTLAQQYSTDNDVYIITGDKDLLQCINDNVEVWLIKKGFNIY
                     NRYTLHRFNEEYDLEPQQLIDIKAFMGDTADGYAGVKGIGEKTAIKLIQQYQSVENVV
                     ENIDALSAGQRNKINDNLDELYLSKRLAEIHTQVPIDSEALFEKMSFATTLNHILSIC
                     NEHELHV"
     gene            complement(870..4310)
                     /locus_tag="RPH49_002446"
     CDS             complement(870..4310)
                     /locus_tag="RPH49_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HDY5125564.1"
                     /translation="MINKEQLDLLYKLKKEVEKSRNEALLHTINQVIKKVYLQQYTCS
                     FVGHFSAGKSTLINLLIEQDILPSSPVPTTSNTAIVSVSDNHDIIANLPNQTYAKLSN
                     YDEVREMNRQNVDVESVEINFQSTKFENGFTLQDTPGVDSNVASHQSITEQYMYTSNM
                     IFYTVDYNHVQSELNFKFMKHINDVGIPVVFIINQIDKHQDDELSFSTFKSRVEKSIA
                     DWGIKLERIFYVSKFDHPENELEVLSTYLVSLDQHRETIEDYTLRTVEYITEAQLDYI
                     QSEIQEVLEDLGIEEAEFEQAFLNSQQHQAISEEAQLLNNPDELMAFLKNKRKNILEN
                     AYIMPHNMREMLRSYLESMSQDFNVGGFFNKKKKKLQIQQQRLLTATDALQEHVNQQI
                     RQPMREDMSFVTRFINKKEASDKVLNQHYDVKSEMIEALYQPQTSISNTYVLTFSDEV
                     VKAIKKYVEQQSTPIFKEIIENVQADELPTEESDDLKEYQRYTELNELRQSLTTKNYR
                     HYYIHLDESLDKLVDRQETTYQVATDNAQGNRDNQQLNQNTATTNMSIDIQKALDIIS
                     DVPLFKRTKQDIHETLTRIDNKLIKIGVFGTFSAGKSSLINALLGEHILVSSPNPTTA
                     ATTEISYGDESYITLKSQSQLLDEINAVVEYQDISFSTIEDFINSDLEKLKSHLNKNQ
                     LAFVHAVEKHYKLYVSMLENGEKHAINQQELKKWSAEDEYATFVKTVHIALMHDWLKG
                     KIIVDSLGLHSNNQRHTNETEQILTSSDLILYVSYFNHSFTDNDKAFIEHMKDMNQLN
                     ENQAFKMVINAADLAESQDDLEAVETYVSDALRQVHLQSDIFAVSSRNALQAEDKGID
                     QLKQSIQQFVDVDSKSILEQQMIHQLQQMDRSYVEMITEFETNKADISRRQQRLTDYK
                     DKQRLQHQLIDATLQHTDNEVEEQVYHLNARLKLQLLDDVKSVFNSQMTQNSDFNEEK
                     KVSTKVYLDQIHQRLFLEQSLITERIKKYFNKQLTEQIAPIVQQLADLHVIVNPQFNF
                     ESANIEQPLLHIDFNDMLNALPKQLTKRKILNPNGQRDIHESICQSTLGLLQPQMGLL
                     RQQLELYVKQMAVEAESQFESFEANIQTQINDLLAFDLDTTLINQLKDKHQQLKTILY
                     "
     gene            4614..5954
                     /locus_tag="RPH49_002447"
     CDS             4614..5954
                     /locus_tag="RPH49_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDY5125565.1"
                     /translation="MKNTFNPLQRLHFYAAIFIAPLLITLTISGIGYLFFPEVENNIY
                     KNKFFGDSDVKTHQTLNDAVHQVEQQYEGFFVSKVSILDEPYNKRITLSDMAGNQRYV
                     FLDRNNQFVADQNAKHTYSNVMRSIHSSLFTENTIINYLVELTACWTIFMILSGTYLL
                     IKKHLISNKSKALRWQKWHAMIGVIIAIPVFVLVITGLPWSGFMGSKIAGMMDTNGDL
                     GQGELAINPPKSDLNELPWATRKNKQPASSEKGSSGHHGNAAMPQTKLDYQISIDKVV
                     EQAQKSGIKKPFSIVYPSDRNGAFIVSNTSNSGVTGLDVSPYKEQTLYFDQYSGKKLG
                     TIKYDDYGIIAKWFTWGIPLHEGHLFGILNKIINLFVCIALLVAIGMGFVSWIKRTKN
                     TAVKVPHRVKKPASISLIICLIVLGLLMPLFGLSLILVFIIELILYIKDRRAKQ"
     gene            complement(6163..6495)
                     /locus_tag="RPH49_002448"
     CDS             complement(6163..6495)
                     /locus_tag="RPH49_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4889 domain-containing protein"
                     /protein_id="HDY5125566.1"
                     /translation="MGKKMGLGLSIALVVIGIAVVCLMIFSSQKTTYFGYMNSNTNAE
                     KVVSEKDGLVKHNIKVEPSNDFKPKKGDFVKLVSKDGGKTFYKQEIVKHDDVPHGLMM
                     KIHDMHMN"
     gene            complement(6579..7724)
                     /locus_tag="RPH49_002449"
     CDS             complement(6579..7724)
                     /locus_tag="RPH49_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDY5125567.1"
                     /translation="MFQLLAVCPMGLEAVVAREIQELGYETNVENGRIFFEGDASAIV
                     KANLWLRTADRIKIVVGRFNATTFDELFEQTKALPWESIIDKEGNFPVQGRSVKSTLH
                     SVPDCQAITKKAIVERLRRAYNEKGWLNESGAKYPVEVAILKDNVLLTIDTSGSGLNR
                     RGYRLAQGEAPIKETLAASLIRLANWKGDTPLIDPFCGSGTIAIEACLIAQNIAPGFN
                     REFVSEQWNIMPANIYDDYRDEADKMADYDKEIEVYASDIDPEMVEIAKRNAEEVGLS
                     DIIKFSVKDVNTLTIDTEEPVALIGNPPYGERIGDREEVEEMYRYIGKLMKQHPFLST
                     YILTSNKEFEYLVDRKATKRRKLFNGYIECTYYQYWGKKTERKTIEN"
     gene            complement(7933..8312)
                     /gene="rnpB"
                     /locus_tag="RPH49_002450"
     ncRNA           complement(7933..8312)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RPH49_002450"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            complement(8375..>8465)
                     /locus_tag="RPH49_002451"
     CDS             complement(8375..>8465)
                     /locus_tag="RPH49_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDY5125568.1"
                     /translation="SNNTTTNTSSNNVDILKRISNLEKAVFGK"
BASE COUNT         2625 a         1468 c         1237 g         3135 t
ORIGIN      
        1 aaacatgtaa ttcatgttcg ttgcaaattg ataaaatatg attaagcgtt gttgcaaatg
       61 acattttctc aaaaagcgct tcactatcaa ttggtacttg tgtgtgaatt tcagccagtc
      121 gcttcgataa atatagttca tctaaattgt cattaatctt attacgttgt ccagctgata
      181 atgcatcaat gttttcaacc acattttcaa cgctttgata ttgctgaatt aacttaatag
      241 ccgttttctc accaattcct ttaacacctg catatccatc tgctgtatca cccataaacg
      301 ctttaatatc gattagttgt tgtggttcaa ggtcatattc ttcgttaaaa cgatgtaatg
      361 tatatctatt ataaatgtta aaaccttttt taattagcca aacttcaaca ttgtcattaa
      421 tacattgcag taaatctttg tcgcccgtaa taatatagac atcgttatca gttgaatatt
      481 gttgtgctaa tgtacctata acatcatccg cttcatagtt tttaacgcca atatttacaa
      541 agccaaattg ctctgaaatt tctttaacat aatcaaattg tggtatcaat tcttctggtg
      601 gtgcagaacg attttgctta taaccatcaa acatatcatt tctaaaagtt gattgtccca
      661 tatcccaaca tacagctaca tgtgtagggc gtatttcatg tattgccgaa aagatatgac
      721 gcacaaatcc ttgtattcca tttgtaggta caccttgtga attgtacata aattgtttat
      781 gaagacttgt agcgtagaaa tgtctaaata atagcgccat accatctaca agtaatattt
      841 tatttggcat ttaaaacgtt ccttctttct taatataaaa tagttttcag ttgttgatgt
      901 ttatctttca attgattgat aagtgttgta tctaaatcaa atgctaataa atcgtttatt
      961 tgcgtttgaa tattagcttc aaaactttca aattgcgatt cagcttctac agccatttgc
     1021 tttacatata attcaagctg ttgcctcaat aatcccattt gtggttgtaa taatcctaac
     1081 gtactttgac aaattgattc atgtatatct ctttgcccat ttggattcaa aattttacgt
     1141 tttgttaatt gtttaggcaa tgcatttagc atatcattga aatcgatgtg caataatggt
     1201 tgctctatat tagctgattc aaagttaaac tgaggattaa caatgacatg taaatctgct
     1261 aattgttgaa cgattggggc aatttgctca gtgagttgct tattaaagta tttttttata
     1321 cgttctgtaa ttaaagattg ctctaaaaac aatcgttgat gaatttgatc taagtatact
     1381 ttcgtagaca ctttcttttc ttcattaaaa tcactatttt gcgtcatttg agaattaaac
     1441 actgatttaa catcgtcaag tagttgtaat tttaaacgtg catttaaatg ataaacttgt
     1501 tcttcaactt cgttgtctgt atgttgtagc gtcgcatcaa ttaattgatg ttgtaaacgc
     1561 tgtttatctt tatagtctgt taacctttgt tggcgacgtg aaatatcagc tttatttgtt
     1621 tcgaattctg taatcatctc tacataagaa cgatccattt gctgaagctg atgaatcatt
     1681 tgttgttcta aaattgattt agaatcaaca tcaacaaatt gttgtatgct ttgttttaat
     1741 tgatcaatgc ccttatcttc agcttgcaat gcatttcgac ttgatacagc aaaaatgtct
     1801 gattgtaagt gtacttgtct taatgcatct gatacatatg tttcaaccgc ttcaagatca
     1861 tcttgacttt ctgctaaatc agcagcatta attaccattt taaatgcttg gttttcattc
     1921 aactggttca tatctttcat gtgttctata aacgccttgt cattatcagt aaatgaatga
     1981 ttaaaataac tcacatacaa tattaagtct gaagaagtta aaatttgctc tgtttcattt
     2041 gtatgccttt ggttatttga gtgtagccct aaggaatcaa caattatttt accttttaac
     2101 caatcatgca ttaatgcaat gtgtactgtt ttaacaaatg ttgcatattc atcttctgca
     2161 ctccactttt tcaattcttg ttgattaatg gcatgttttt ctccgttttc caacatactg
     2221 acatacaatt tataatgttt ttcaactgca tgaacaaaag cgagttgatt tttatttaaa
     2281 tgtgatttta acttttctaa atctgaatta ataaagtctt ctatagttga aaaagatata
     2341 tcttggtatt caactactgc attaatttca tctaataatt gcgattgtga ttttagcgtt
     2401 atataactct cgtctccata agatatttct gtagtagctg ctgtagtagg atttggagaa
     2461 ctgactaaaa tatgctcgcc taataatgca tttatcaaac tacttttacc cgcactaaat
     2521 gttccaaata cgcctatttt tattaattta ttatctatac gtgttaatgt ttcgtggata
     2581 tcctgctttg tacgcttgaa caaaggcaca tccgaaatta tatcaagtgc tttttgaata
     2641 tctatagaca tatttgttgt agcggtattc tgatttagct gttgattatc tcgattaccc
     2701 tgagcattat cagtagccac ttgatatgtt gtctcttgtc gatctactaa tttatctaga
     2761 gattcatcta aatgaatata gtagtgacga taattcttag tcgtcaatga ctgacgcagc
     2821 tcatttaatt ctgtataacg ttgatattct tttaaatcat cactttcttc tgttggtaat
     2881 tcatctgcct gcacattttc tataatttct ttaaaaatcg gtgttgactg ttgttcaacg
     2941 tatttcttaa tggctttaac cacttcgtct gaaaatgtaa gtacataagt attgctgatt
     3001 gatgtttgtg gttgatataa agcttcaatc atttccgact taacgtcata atgctgattt
     3061 aatactttat ctgaagcttc ttttttattg ataaaacgtg taacaaatga catatcttct
     3121 cgcattggtt gacgaatttg ttgattaaca tgttcttgta acgcatctgt cgctgttaat
     3181 aatcgctgtt gttgaatttg tagctttttc ttctttttat taaaaaatcc gccaacatta
     3241 aagtcttgag acatactttc caaataactt cgtaacattt ctctcatatt atgcggcata
     3301 atgtatgcat tttctaaaat atttttacgc ttattcttta aaaatgccat taattcatct
     3361 ggattattta aaagttgtgc ctcttcacta attgcttgat gctgttgact atttaaaaat
     3421 gcttgttcaa actctgcttc ttcgataccc aaatcttcta atacttcctg aatttcagac
     3481 tgaatataat ctagctgagc ttcggtaata tattcaaccg ttcttaatgt ataatcctct
     3541 attgtttctc tatgttgatc taatgaaact agataagttg ataatacttc aagttcattt
     3601 tcagggtgat caaatttaga tacataaaag atgcgttcta atttaatgcc ccaatcagca
     3661 attgattttt caactcgaga tttaaacgta gagaatgaca attcatcgtc ttgatgcttg
     3721 tcaatttgat taatgataaa cacaacaggt attccaacat catttatatg cttcataaac
     3781 ttaaagttaa gttcagattg aacgtggtta tagtcaaccg tataaaatat catattgctt
     3841 gtatacatat attgttctgt tattgactga tgtgatgcaa catttgaatc aacacctggt
     3901 gtatcttgca acgtaaaccc attttcaaat ttagttgatt gaaaattaat ttctacagat
     3961 tcaacgtcga cattttggcg attcatttcc cttacttcat cataattaga taatttggca
     4021 tacgtttgat tcggcaaatt agcaataata tcgtgattgt ctgaaactga cacgatagca
     4081 gtattacttg tcgttggtac aggtgaactt ggtaagatat cttgttcaat taataaattt
     4141 atcagtgtcg atttacctgc agaaaaatgt ccaacgaacg aacatgtata ttgctgcaaa
     4201 tatactttct taattacttg gttaattgta tgtaaaagtg cttcatttcg cgacttttca
     4261 acttcttttt ttaatttata taaaagatct aattgttctt tattaatcat gttactttcc
     4321 cctttggttc gttcacatag aaatgcttgc ttgttaaaac gaattcatac aatatcgata
     4381 tccatttaaa caaagatcgt tgaatggctc gcattgtatt atgtttaaat tttatcatag
     4441 ctgcttgata aaacatacga ataatcaatt ttcttcaaac attccaactt aaaagttcat
     4501 ttttctaaat atcacaaatc atcgttaaat ttttctagaa aataaatatt gtcacagttt
     4561 gttcacacac gtcacagaat tgacaccgta taatagccaa ttgggaggga aatatgaaaa
     4621 atacatttaa tccattacaa agattacatt tctatgcagc aatatttatt gctccactgt
     4681 taatcacttt aaccatttcg ggcattggtt acttgttctt tccagaagtt gaaaataata
     4741 tttataagaa taagtttttt ggtgacagtg atgtaaaaac gcatcaaaca ttaaatgatg
     4801 cagtacatca agttgaacaa caatatgaag gattctttgt aagtaaagtt agcatacttg
     4861 atgaaccata taacaaacga attacactga gtgatatggc aggaaatcaa cgttacgtct
     4921 ttctagatcg taacaatcaa tttgttgcag atcaaaatgc gaaacatacg tattctaatg
     4981 tgatgcgaag tatacatagt tctttgttta ctgaaaatac tattattaat tatttagtag
     5041 agttaaccgc atgttggacg atattcatga ttttatctgg tacttattta ctcattaaga
     5101 agcatttaat ttctaacaaa agtaaggcac ttcgttggca aaagtggcac gcaatgattg
     5161 gagttatcat tgcaattcca gtatttgtat tagtcataac tggattgcca tggtctggtt
     5221 ttatgggtag taaaattgcc ggtatgatgg acacaaacgg tgaccttggt caaggtgaat
     5281 tagcgattaa tccacctaaa tcagatttga acgaattacc ttgggctaca cgtaaaaata
     5341 aacagccagc ttcatccgaa aaaggttcaa gtggtcatca tggtaatgca gcaatgcctc
     5401 aaaccaaatt agattatcaa atatctattg ataaggtcgt tgaacaggcg caaaaatctg
     5461 gtattaaaaa gccgttttca atcgtatatc caagtgatag aaatggtgcc tttattgtat
     5521 ctaatactag taattcaggt gttactgggc tagatgtatc accttacaag gaacaaacac
     5581 tttatttcga tcaatatagc ggtaaaaagt taggtacgat taaatatgat gactacggta
     5641 ttattgctaa atggtttaca tggggcattc cgcttcacga aggtcattta ttcggcattt
     5701 taaataaaat cattaattta tttgtatgta tcgctttatt agtagccatt ggcatggggt
     5761 ttgtctcttg gataaagcgt acaaaaaata ctgcagtaaa agtaccacat cgcgtaaaaa
     5821 aaccagcatc tatatcactc ataatatgtt taattgtatt aggattatta atgccattat
     5881 ttggattatc acttatcctt gtatttataa ttgaattaat attatatatt aaagatcgtc
     5941 gtgctaaaca ataatgcact taaagttttg aactgacgaa atttacaaaa tgattctcga
     6001 cactataatt acttaaaacg ggttctataa taaatcgtac tgatgaaaaa gttttttact
     6061 tttccatcag tacgattttt tgaatttgaa gataaaaaag catctaaaac gcataagaag
     6121 ataactctac ttcttccaaa ttacgttata gatgcttttt tattaattca tatgcatgtc
     6181 gtgaattttc atcattaaac cgtgtgggac gtcatcatgt ttaacaatct cttgtttata
     6241 aaatgtcttc ccaccatctt tagaaactaa ttttacaaag tctccttttt tcggcttgaa
     6301 atcattagat ggttctactt tgatattatg tttgactaat ccatcttttt cactgacaac
     6361 tttttctgca tttgtattac tattcatata accaaaataa gtcgtttttt gactagaaaa
     6421 aatcattaaa catacaacgg caataccaat aacaaccaat gctatagata aacctagacc
     6481 cattttttta cccatttata gactcctcca tttttcaaaa atacctatta tcatgagaac
     6541 ataattatta ctaattttag tcacgcatta taaacacttt agttttcgat agttttacgt
     6601 tctgtctttt taccccagta ttgataataa gtacattcta tatatccatt aaataactta
     6661 cgtcgcttcg ttgctttacg atctactaaa tattcaaatt ctttattact tgttaaaatg
     6721 tatgtagata aaaatggatg ttgtttcatt agtttaccaa tataacggta catttcttca
     6781 acttcttcac gatcaccaat acgttcacca tatggaggat ttccaattaa cgccaccggt
     6841 tcttctgtat caattgttaa tgtattgaca tcttttacac taaatttaat aatatcagac
     6901 aacccaactt cttcagcatt acgcttagca atctctacca tttctggatc aatatcagaa
     6961 gcatatactt cgatttcctt atcataatca gccatcttat ccgcttcatc acggtaatca
     7021 tcataaatat ttgctggcat gatgttccat tgctctgata cgaattcgcg attaaaacca
     7081 ggtgcgatat tttgagcaat taaacaagct tctatagcta tagtacctga accgcaaaat
     7141 ggatcaatta aaggtgtatc acctttccag tttgcgagac ggattaaact tgctgccaac
     7201 gtttctttaa ttggtgcttc accttgtgct aatctatatc cacgtctgtt caaaccagaa
     7261 cctgatgtgt cgatggtcaa taatacatta tcttttaaaa tggcaacttc aacagggtat
     7321 ttggcacctg attcatttaa ccaacccttt tcgttatatg cacgacgtaa tcgttcaaca
     7381 atagctttct tagttatcgc ctgacaatct ggcacactat gtagtgttga tttaacgctt
     7441 ctaccttgaa ctgggaagtt accttcttta tcaataatag attcccaagg gagcgctttg
     7501 gtttgttcga ataattcgtc aaacgttgtt gcgttaaaac gtccaacaac aattttgatt
     7561 cggtctgctg tgcgcaacca taaatttgcc tttacaattg cacttgcgtc tccttcaaaa
     7621 aatatacgac cattttcaac atttgtttca tagcctaatt cttgaatttc cctagcaaca
     7681 acagcttcta atcccatcgg acaaactgca agtaattgaa acatatatga ttctcctttt
     7741 atacaggtat tttattctta gcttgtgttt tttatacatt tccaacaaat ttaatcgctg
     7801 atacattaac gcattcgctt attattttaa aacaaggcag tgtcattata tcaagacaag
     7861 gcgttaattt taagtgttct tttcatgaaa aaagctctcc atcatctagg agagctaaac
     7921 tagtagtgat atttctataa gccatgttct gttccatcgt actcatcacg tgcactagtc
     7981 acactggtac tcaggtgata accatctgtc tacaccactt catttcgcga agtgtgtctc
     8041 gtttatacgt tgaattccgt taaacaagtg ctcctaccaa atttggattg ctcactcgag
     8101 gggtttaccg cgttccacct tttatatttc tataaaagct acgtcactgt ggcactttca
     8161 aattactcta tccatatcga aagacttagg atatttcatt gccgtcaaat taatgccttg
     8221 atttattgtt tcatcaagca cgaacactac aatcatctca gactgtgtga gcatggactt
     8281 tcctctatat aatatagcga ttacccaaaa tatcactttt aaaattataa catagtcatt
     8341 attagtaaga cagttaaact tttatattta gtaattattt accaaataca gctttttcta
     8401 agtttgaaat acgttttaaa atatctacat tatttgaaga tgtatttgtt gttgtattat
     8461 tcgaa
//
LOCUS       DAPSKH010000086         8341 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPSKH010000086 DAPSKH010000000
VERSION     DAPSKH010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8341
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.086"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            73..1251
                     /gene="deoB"
                     /locus_tag="RPH49_002452"
     CDS             73..1251
                     /gene="deoB"
                     /locus_tag="RPH49_002452"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDY5125569.1"
                     /translation="MTRPFNRVHLIVMDSVGIGEAPDAADFKDEGSHTLRHTLEGFDQ
                     TLPNLEKLGLGNIDKLPVVNAVEQPEAYYTKLSEASVGKDTMTGHWEIMGLNIMQPFK
                     VYPNGFPEELIQQIEEMTGRKVVANKPASGTQIIDEWGEHQMKTGDLIVYTSADPVLQ
                     IAAHEDIIPLEELYDICEKVRELTKDPKYLIGRIIARPYVGEPGNFTRTSNRHDYALK
                     PFGKTVLDHLKDGGYDVIAIGKINDIYDGEGVTEAVRTKSNMDGMDQLMKIVKKDFTG
                     ISFLNLVDFDALYGHRRDKPGYAQAIKDFDDRLPELFSNLKEDDLVIITADHGNDPTA
                     PGTDHTREYIPVIMYSPKFKGGHALESDTTFSSIGATIADNFNVTLPEFGKSYLKELK
                     "
     gene            complement(1382..2197)
                     /gene="phnE"
                     /locus_tag="RPH49_002453"
     CDS             complement(1382..2197)
                     /gene="phnE"
                     /locus_tag="RPH49_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDY5125570.1"
                     /translation="MTQEIAKYNVHTKAHKRKLIKRWLIAIVVLAIIIWAFAGVPSLE
                     LKSKSLEILKSIFSGLFHPDISYIYIPDGEDLLRGLLETFAIAVVGTFIAAIICIPLA
                     FLGANNMVKLRPVSGVSKFILSVIRVFPEIVMALIFIKAVGPGSFSGVLALGIHSVGM
                     LGKLLAEDIEGLDFSAVESLKASGANKIKTLVFAVIPQIMPAFLSLILYRFELNLRSA
                     SILGLIGAGGIGTPLIFAIQTRSWDRVGIILIGLVLMVAIVDLISGSIRKRIV"
     gene            complement(2194..2994)
                     /gene="phnE"
                     /locus_tag="RPH49_002454"
     CDS             complement(2194..2994)
                     /gene="phnE"
                     /locus_tag="RPH49_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDY5125571.1"
                     /translation="MPLEIPTKYDSLLKKKVSLKTSFTFMLIIVLIIWSFIYTGFNFG
                     DLMIGIPQIGDLFKQMIPPDFEYLQQITTPMLDTIRMAIVSTVLGSIVSIPIALLCAS
                     NIVHQKWISIPSRFILNIVRTIPDLLLAAIFVAVFGIGQIPGILALFILTICIIGKLL
                     YESLETIDPGPMEAMTAVGANKIKWIVFGVVPQAISSFMSYVLYAFEVNIRASAVLGL
                     VGAGGIGLFYDQTLGLFQYPKTATIILFTLVIVVVIDYISTKVRAHLA"
     gene            complement(2996..3769)
                     /gene="phnC"
                     /locus_tag="RPH49_002455"
     CDS             complement(2996..3769)
                     /gene="phnC"
                     /locus_tag="RPH49_002455"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDY5125572.1"
                     /translation="MSQIEFKNVSKVYPNGHVGLKNINLNIEKGEFAVIVGLSGAGKS
                     TLLRSVNRLHDITSGEIFIQGKSITKAHGKALLEMRRNIGMIFQHFNLVKRSSVLRNV
                     LSGRVGYHPTWKMVLGLFPKEDKIKAMDALERVNILDKYNQRSDELSGGQQQRISIAR
                     ALCQESEIILADEPVASLDPLTTKQVMDDLRKINQELGITILINLHFVDLAKEYGTRI
                     IGLRDGEVVYDGPASEATDDVFSEIYGRTIKEDEKLGVN"
     gene            complement(3983..4939)
                     /locus_tag="RPH49_002456"
     CDS             complement(3983..4939)
                     /locus_tag="RPH49_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDY5125573.1"
                     /translation="MKNFKCLFVLMLAVIVFAAACGNSSSLDNQKNASNDSDSKSGGY
                     KPKELTVQFVPSQNAGTLEAKAKPLEKLLSKELGIPVKVSVSTNYNTIVEAMKSKKVD
                     VGFLPPTAYTLAHDQKAADLLLQAQRFGVKEDGSASKELVDSYKSEILVKKDSKIKSL
                     KDLKGKKIALQDVTSTAGYTFPLAMLKNEAGINATKDMKIVNVKGHDQAVISLLNGDV
                     DAAAVFNDARNTVKKDQPNVFKDTRILKLTQAIPNDTISVRPDMDKDFQEKLKKAFID
                     IAKSKEGHKIISEVYSHEGYTETKDSNFDIVREYEKLVKDMK"
     gene            5168..6712
                     /locus_tag="RPH49_002457"
     CDS             5168..6712
                     /locus_tag="RPH49_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDY5125574.1"
                     /translation="MKKIYKSLTVSAIVATISLSVLPQSLAITHESQHTKQQRTVLFD
                     RSHGQTAGAADWVSDGAFSDYADSIQKQGYDVKAIDGHSNITEASLKSSKIFVIPEAN
                     IPFKESEQAAIVNYVKHGGNVVFISDHYNADRNLNRIDSSEAMNGYRRGAYEDMSKGM
                     NAEEKSSTAMQGVKSSDWLSTNFGVRFRYNALGDLNTSNIVSSKESFGITEGVKSVSM
                     HAGSTLAITNPEKAKGIVYTPEQLPAKSKWSHAVDQGIYNGGGKAEGPYVAISKVGKG
                     KAAFIGDSSLVEDSSPKYVREDNGEKKKTYDGFKEQDNGKLLNNITVWMSKDNDGKSL
                     KASGLTLDTKTKLLDFERPERSTEPEKEPWSQPPSGYKWYDPTTFKVGSYGSEKGADP
                     QPNTPDDHTPPNQNEKVSFDIPQNVSVNEPFEVTIHLKGFEANQTLENLRVGIYKEGG
                     RQIGQFSSKDNDYNPPGYSTLPTVKADENGNATIKVNAKVLESMEGSKIRLKLGDKTL
                     ITTDFK"
     gene            6763..8298
                     /locus_tag="RPH49_002458"
     CDS             6763..8298
                     /locus_tag="RPH49_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDY5125575.1"
                     /translation="MSNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRR
                     QYDQSFKIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNYGLPY
                     LKDTLRRLNYPVLCANIYENDSTLTDNGVQYFQVGGQTVGVIGLTTQFIPHWEQPEHI
                     QSLTFHSAFETLQQHLPEMKRHADIIVVCYHGGFEKDLESGTPTEVLTGENEGYAMLE
                     AFSKDIDIFITGHQHRQIAERFKQTAVIQPGTRGTTVGKVVLSTDEYENLSVESCELL
                     PVIDDSTFTIDEDDQHLRKQLEDWLDYEITTLPYDMTINHAFEARVAPHPFTNFMNYA
                     LLEKSDADVACTALFDSASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSA
                     EYFDVKNDKVSVSADFLEPKPQHFNYDIYGGVSYTINVGRPKGQRVSNMMIQGHAVDL
                     KQTYTICVNNYRAVGGGQYDMYIDAPVVKDIQVEGAQLLIDFLSNNNLMRIPQVVDFK
                     VEK"
BASE COUNT         2787 a         1382 c         1538 g         2634 t
ORIGIN      
        1 ggtgttcaaa ttatgcaagg tttagaagca gattcagatt actaatatat ataaaatttg
       61 ggagtgatag ctatgacaag accatttaat cgtgtacatt taatcgtaat ggattcagta
      121 ggtattggtg aagcgccaga cgcagctgat tttaaagatg aaggttcaca tactttaaga
      181 cataccttag aaggcttcga tcaaacttta ccaaaccttg aaaagttagg tctagggaac
      241 atcgataaat taccagtagt aaatgcagtt gaacaaccag aagcatacta tactaaattg
      301 agtgaagctt cagttggtaa agatacaatg actggtcact gggaaattat gggattaaat
      361 attatgcagc cttttaaagt ataccctaat ggattccctg aagagttaat tcaacaaatt
      421 gaagaaatga caggtcgtaa agttgttgct aacaaaccgg catcgggtac gcaaattatc
      481 gatgagtggg gcgagcacca aatgaaaact ggtgacttaa ttgtttatac aagtgcagac
      541 ccagtattgc aaattgctgc acatgaagac attatcccat tagaagagtt atatgatatt
      601 tgtgaaaagg ttcgtgagtt gacaaaagac cctaaatatt taattggtcg tattatcgca
      661 cgtccatatg ttggtgaacc aggaaacttt acacgtacat ctaatcgaca tgactatgcg
      721 ttaaaacctt ttggtaaaac tgtcttagat catttgaaag acggtggtta tgatgttatt
      781 gccatcggta aaattaatga catttatgat ggtgaaggtg taacagaagc ggttcgtacg
      841 aagagtaaca tggacggtat ggatcaattg atgaaaattg ttaagaaaga tttcacaggt
      901 attagcttct taaacttagt agactttgat gcattatacg gtcatcgtcg tgataaacca
      961 ggttatgcac aagcaattaa agatttcgat gatcgcttgc cagaactgtt tagcaactta
     1021 aaagaagacg atttagtaat tattacagca gaccatggta atgacccgac agcgccaggt
     1081 acggaccata cgagagaata tatcccagta attatgtaca gtccgaaatt taaaggtggt
     1141 catgcactag aaagtgatac tacattcagt tctatcggtg caactatagc agataatttc
     1201 aacgtaacat taccagagtt cggtaaaagt tatttaaagg aattgaaata gaataaattt
     1261 agatattata aaaacagcag tgaagttaac tataacaata gttttcttca ctgctgtttt
     1321 tattataata gagaaacgta agacggtagg acctcttatt taggagtatc ctgatttaat
     1381 gttaaacaat acgttttcgg attgaaccgg aaattaaatc gacaattgcg accattagta
     1441 ctaaaccgat taatataata cctacacggt cccaagaacg tgtttgaatg gcaaatatga
     1501 gtggtgtccc gataccacca gccccaatta gccccagtat agaagctgaa cgtaagttta
     1561 gttcaaagcg ataaagtatg agtgatagaa aggcaggcat aatttgtggt atgactgcaa
     1621 atacgagtgt tttaatctta ttcgcaccac tggcctttaa tgattctaca gcactgaaat
     1681 ctagaccttc aatatcttca gctaaaagtt tcccaagcat acctacagaa tggataccta
     1741 aagctaatac acctgaaaat gaacctgggc caacagcttt gataaatata agtgccatta
     1801 caatttctgg gaagacacgt ataacactta aaataaattt gctaacacct gaaaccgggc
     1861 gtaactttac catattattt gcacctaaaa atgctaatgg aatacagata attgcggcga
     1921 tgaaagtacc tacaacggct atcgcaaagg tttcaagtaa accacgtaat aagtcttcgc
     1981 catctggtat atagatatag ctaatatctg gatggaataa tccgctgaat atggatttta
     2041 agatttctaa tgatttactt ttaagttcta aacttggtac acctgcaaat gcccagatga
     2101 taatagctaa gacgacaatt gcaataagcc atcttttaat caattttcgt ttgtgtgctt
     2161 ttgtgtgaac attatatttt gctatttcct gtgtcatgcg agatgtgccc tcactttcgt
     2221 actgatgtaa tcaatgacga cgacgataac taaagtaaat aaaataatcg ttgctgtttt
     2281 tggatattga aataaaccaa gtgtttgatc ataaaacaat ccaataccgc cagcgccgac
     2341 taatccaagc acagctgaag cacgtatatt tacttcaaat gcatataata cgtatgacat
     2401 aaatgacgat atggcttgtg gtacaacacc gaaaacaatc cattttattt tattagcgcc
     2461 aacagccgtc attgcttcca ttggacctgg atctatcgtt tccaatgatt catataataa
     2521 ttttccaata atacagatag ttaaaataaa caatgctaat atccctggaa tttgaccgat
     2581 tccaaataca gccacaaaga ttgctgctaa taacaaatct ggaatagtac gaactatatt
     2641 taaaataaag cgcgagggta ttgaaatcca cttttgatga acgatattgc tagcacataa
     2701 taacgcaatt ggtattgaaa cgatgctacc taatactgta cttacgatag ccattcgaat
     2761 ggtatctaac attggcgttg taatttgttg taaatactcg aaatcaggtg gaatcatttg
     2821 tttgaataga tcacctattt gaggtattcc tatcattaaa tctccaaaat taaaccccgt
     2881 ataaatgaag ctccaaatga taagcacaat gattaacatg aaggtaaaac tcgtttttaa
     2941 agaaaccttt ttctttaaaa gggagtcata ctttgtaggt atttctaaag gcatgttagt
     3001 tcactcctag cttttcatct tctttaattg tacgtccata tatttcacta aatacgtcat
     3061 ctgttgcttc agatgcagga ccatcataga caacttcacc atcacgtaaa ccaatgatgc
     3121 gtgtgccata ttcttttgcc aagtcaacaa aatgtaaatt aattaaaatt gtgatgccta
     3181 attcttggtt gatttttctt aaatcatcca taacctgttt cgttgttaat gggtctaatg
     3241 aagcaactgg ttcatctgca agaataattt cggattcttg gcatagcgca cgtgcaatag
     3301 atatacgttg ttgttggcca cctgataatt catcagagcg ttgattatat ttatctaaga
     3361 tattgacgcg ttctagtgca tccattgctt taattttgtc ttcttttggg aataaaccta
     3421 ataccatttt ccaagtaggg tgataaccta cacgtccact tagtacattt cgtaatacac
     3481 ttgaccgttt aactaaatta aaatgttgga aaatcatacc tatatttcgg cgcatttcta
     3541 ataatgcttt accatgggct ttagtgatgg atttgccttg gatgaaaatt tcacctgacg
     3601 tgatatcatg caaacgattt acagatctta ataacgtgga tttcccagca ccagatagtc
     3661 cgacaataac tgcaaattca cctttttcaa tatttaagtt aatatttttc aagcctacat
     3721 gaccgttagg atagacttta ctgacgtttt taaattcgat ttgactcatg tttgacacct
     3781 ttctttaata aagaaaagcc aaggtaaact gaaatatcat agacattggg tttctgtgta
     3841 caaatggttt caaatgtaca gcgacacctt tctatatctg tttcagttta gcgcctagct
     3901 tttcaatatt aatctagaat atatctattg aacgaaagct tttaatacca aattcgctaa
     3961 tgattcattt gttaaataat gattatttca tatctttaac taatttttcg tactctctta
     4021 caatgtcgaa atttgaatct ttcgtttctg tgtatccttc atgtgaataa acttcgctaa
     4081 taattttgtg accttctttt gatttagcaa tgtctataaa agcttttttc aatttttctt
     4141 gaaaatcttt atccatatct ggtcttacag aaattgtgtc attcggaata gcttgtgtta
     4201 attttaaaat tcgtgtgtct ttaaatacat ttggttggtc ttttttcaca gtattacgtg
     4261 catcattaaa tacagccgca gcatctacat ctccatttaa taatgagata actgcttggt
     4321 catgaccttt aacattcaca attttcatat ctttagttgc attaatacct gcttcgtttt
     4381 ttaacatcgc aagtgggaat gtatatccag cagttgatgt tacatcttgt aaggcaattt
     4441 tcttaccttt taaatctttc aagcttttaa tttttgagtc ttttttaaca agaatttctg
     4501 atttataact atctacaagt tctttacttg ctgaaccatc ttcttttaca ccaaaacgtt
     4561 gtgcttgtaa taataaatca gctgcttttt gatcatgtgc taatgtgtat gccgttggtg
     4621 gtaagaaacc aacatcaact tttttagact tcatagcttc aacaattgta ttgtagttag
     4681 ttgatacaga cactttaact ggaattccta attctttaga tagtaatttt tctaatggtt
     4741 ttgctttagc ctctaatgtt ccagcatttt gcgaaggtac aaattgtact gttaattctt
     4801 taggtttgta tcctcctgat ttagaatccg aatcattact agcgttcttt tgattatcta
     4861 aagaacttga gtttccacat gctgctgcaa aaacaatgac tgctaacatt aatacaaata
     4921 aacacttaaa atttttcatt tgataactgt ccccttcaca ttcttaatcg tgtaatatgt
     4981 atgcaatgaa attacactta tagcgtacca catttaaatg cgaaaaagta ttttataaaa
     5041 atgaatttta ataactttct ttaagagtgt gataagattt tgtaaacttt tcgttaaatt
     5101 gctcatatgc aacgaatttt tatcttataa ttcaagaaca aatttatttt aaaaggagcc
     5161 tcaaaaaatg aaaaaaatat ataagtcatt aactgtctct gcaattgttg caacgatatc
     5221 attaagtgtg ctaccgcaat ctttagctat aacgcatgaa tcgcaacata caaagcaaca
     5281 gcgaacggta ttattcgatc gttctcatgg tcaaacagct ggtgctgcag attgggttag
     5341 tgatggtgca ttttcagatt atgcggattc aatacaaaaa caaggttatg acgttaaagc
     5401 tattgatggt cattcgaaca taacagaagc aagtttgaaa agttccaaaa tatttgtaat
     5461 tcctgaggct aacattcctt tcaaagaatc agaacaggca gcaattgtta actatgtgaa
     5521 acatggtggc aatgttgtct ttatttcaga tcattacaat gctgaccgaa atttaaatcg
     5581 tattgattca tcagaggcaa tgaatggtta tcgacgtgga gcgtatgaag atatgtcgaa
     5641 aggtatgaat gcagaagaaa aaagttctac tgcaatgcaa ggtgtgaaaa gttcagattg
     5701 gttatctaca aactttggcg tacgttttcg atataatgca ctaggtgatt taaatacgag
     5761 caatattgtt tcttcaaaag aaagtttcgg tattactgaa ggtgtgaaat ctgtatctat
     5821 gcatgccgga tcgacattag caattactaa tccagagaaa gcaaaaggta ttgtgtatac
     5881 accagaacaa ttgccagcga aaagtaaatg gtcacatgct gtagatcaag gtatttataa
     5941 tgggggcggt aaagcagaag gtccctatgt agcaatttct aaagttggaa aaggtaaagc
     6001 agcatttatc ggtgattcat cacttgtgga agatagttcg cccaaatatg taagagaaga
     6061 taatggagaa aagaagaaaa catatgatgg ttttaaagaa caagacaacg gtaagctgtt
     6121 aaataatata acggtttgga tgtctaaaga taatgatggg aaatcactta aggcgagtgg
     6181 cctaacatta gatacaaaga ctaagttgct tgattttgaa cgaccagagc gttcaactga
     6241 gcctgaaaaa gagccatggt cacaaccgcc gagtggttat aaatggtatg atccaacaac
     6301 atttaaagta ggtagttatg gcagcgaaaa aggcgcagat cctcagccaa acacaccaga
     6361 tgatcatacg ccaccaaatc agaacgaaaa agtatcattt gatatcccgc aaaatgtttc
     6421 tgtaaatgag ccatttgaag tgacaataca tttaaaagga tttgaagcaa atcaaacact
     6481 tgaaaatctt agagttggta tttacaaaga aggcggacgt caaatcggac aattttcaag
     6541 taaagataac gattataacc cgccaggtta cagtactttg ccaacagtta aagcagatga
     6601 aaacggaaat gccacaatta aggtcaatgc caaagtactc gaaagtatgg aaggttcaaa
     6661 gattcgttta aaactcggtg acaaaacctt gattacaaca gacttcaaat aaatatataa
     6721 tagaaataag aaagatgttt gtgattgaag gagtgagtga ggatgtcaaa catagcattt
     6781 tatgtcgtga gtgacgtaca cggttatatt ttcccaacag attttacgag tagaaatcaa
     6841 tatcaaccta tgggattgtt actagcgaat catgttatag aacaagacag aaggcagtat
     6901 gaccaaagtt ttaaaataga taatggtgat tttttgcaag ggtcaccatt ttgtaattac
     6961 ttaatcgcgc atagcggcag tagccagcct ttagttgatt tttataatcg aatggcattc
     7021 gactttggta cgcttggtaa tcatgaattt aattatggat taccatactt aaaagacact
     7081 ttacgcagac tcaattatcc agttttgtgc gctaatattt atgaaaatga tagtacattg
     7141 actgataacg gtgtgcagta ttttcaggtt ggaggtcaaa cggttggtgt gataggttta
     7201 acgacacaat ttattcccca ttgggaacaa ccagagcata ttcagtcact tacgtttcat
     7261 agtgcttttg aaacacttca acaacacttg cctgaaatga agcgacatgc agatatcatt
     7321 gtggtttgtt accatggtgg atttgaaaag gatttagaaa gtggtacgcc gaccgaagtg
     7381 ttaacgggtg aaaatgaagg atatgccatg ttagaagcgt tttctaaaga tatagatatc
     7441 tttattacgg gtcaccaaca tcgacaaatt gctgaaaggt ttaagcaaac ggctgtgatt
     7501 caacctggta cgagaggaac aactgtaggc aaagtagtct tgagtactga tgaatatgaa
     7561 aatctatccg ttgaatcatg tgaattactt cctgttatag atgattccac atttactatt
     7621 gatgaagatg accaacattt acgaaagcag ttagaggact ggttagatta cgaaattact
     7681 acattgccat atgatatgac gattaatcat gcatttgagg cacgtgtggc accgcatcct
     7741 tttacaaatt ttatgaatta tgctttatta gaaaaaagtg acgcagatgt tgcctgtaca
     7801 gctttgtttg attctgctag tggtttcaag caagtcgtga cgatgcgaga tgtgattaac
     7861 aattacccat ttccaaatac atttaaagtt ttagctgtaa gtggtgccaa acttaaagaa
     7921 gccattgaac gatcagcaga atattttgac gtgaaaaatg ataaagtaag tgtgagcgca
     7981 gacttccttg aacccaaacc acaacacttt aattatgata tatatggtgg cgtaagttat
     8041 accattaatg ttggcagacc aaagggacaa cgtgtgagta atatgatgat tcaaggtcac
     8101 gcagttgatt taaagcagac atatacaatt tgtgtaaata attatcgtgc agttggcggt
     8161 ggtcagtatg atatgtatat cgacgcgcca gttgtaaaag atattcaagt tgaaggcgca
     8221 caattactta ttgatttttt atcaaataat aatttgatgc gcatcccgca agttgttgat
     8281 tttaaagttg aaaagtgacg gatatatgta aaacttactt gattttaatc gggtaagttt
     8341 t
//
LOCUS       DAPSKH010000087         8163 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPSKH010000087 DAPSKH010000000
VERSION     DAPSKH010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 8163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8163
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.087"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            152..1099
                     /gene="hlgC"
                     /locus_tag="RPH49_002459"
     CDS             152..1099
                     /gene="hlgC"
                     /locus_tag="RPH49_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgCB subunit C"
                     /protein_id="HDY5125576.1"
                     /translation="MLKNKILATTISVSLLAPLANPLLENAKAANDTEDIGKGNDVEI
                     IKRTEDKTSNKWGVTQNIQFDFVKDKKYNKDALILKMQGFISSRTTYYNYKNTNHIKS
                     MRWPFQYNIGLKTNDPNVSLINYLPKNKIESTNVSQTLGYNIGGNFQSAPSLGGNGSF
                     NYSKSISYTQQNYVSEVEQQNSKSVLWGVKANSFVTASGQKSAFDSDLFVGYKPNSKD
                     PRDYFVPDSELPPLVQSGFNPSFIATVSHEKGSGDTSEFEITYGRNMDVTHAIKRSTH
                     YGNSYLDGHRVHNAFKNRNYTVKYEVNWKTHEIKVKGQN"
     gene            1101..2078
                     /gene="hlgB"
                     /locus_tag="RPH49_002460"
     CDS             1101..2078
                     /gene="hlgB"
                     /locus_tag="RPH49_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component gamma-hemolysin HlgAB/HlgCB subunit
                     B"
                     /protein_id="HDY5125577.1"
                     /translation="MNMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTL
                     YKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKAAGNINSGYERPNPKDYDFSKI
                     YWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNG
                     NTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNEI
                     FLAGRQSSSYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMD
                     LYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLGTKETENNK"
     gene            complement(2130..2597)
                     /locus_tag="RPH49_002461"
     CDS             complement(2130..2597)
                     /locus_tag="RPH49_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDY5125578.1"
                     /translation="MTSKDITQISVIAAILTILAVLKIPSIIPGLDFQLSAPAALLIL
                     AFFGIKKYFLGGLLSSLLLLVFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLAS
                     VLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR"
     gene            complement(2608..3300)
                     /locus_tag="RPH49_002462"
     CDS             complement(2608..3300)
                     /locus_tag="RPH49_002462"
                     /EC_number="6.2.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxyhexanoate--CoA ligase"
                     /protein_id="HDY5125579.1"
                     /translation="MYSIKMRSSNQDVHISGAETICEFDKIEQTVRRFYNKGFFHENG
                     QPDFLNIKIQKIMEPIQQIKALQITEDDKANLQHLTQECGVTEQALNQGMTYIKNETV
                     YTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPY
                     VKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFL
                     ESTPKQVVYETV"
     gene            complement(3311..4426)
                     /locus_tag="RPH49_002463"
     CDS             complement(3311..4426)
                     /locus_tag="RPH49_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase
                     family protein"
                     /protein_id="HDY5125580.1"
                     /translation="MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSND
                     YLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYNACTILN
                     SGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLAE
                     YPNQNIQKIIISDSVFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGI
                     DILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLIN
                     ADDRRTKLNSLIKYFNQKLKTLNVNYNSSNSPIKFIEFDDIEAAKNIHQTLLKHHVFT
                     SYLRYPTVTKPMLRISLSYFHTEQDVDRLFEILHQED"
     gene            complement(4404..5411)
                     /gene="bioB"
                     /locus_tag="RPH49_002464"
     CDS             complement(4404..5411)
                     /gene="bioB"
                     /locus_tag="RPH49_002464"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDY5125581.1"
                     /translation="MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYF
                     GKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGT
                     YCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYN
                     HNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFAL
                     KEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNL
                     RSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRA
                     N"
     gene            complement(5413..6771)
                     /gene="bioA"
                     /locus_tag="RPH49_002465"
     CDS             complement(5413..6771)
                     /gene="bioA"
                     /locus_tag="RPH49_002465"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDY5125582.1"
                     /translation="MNYTQQLKQKDSEYVWHPFTQMGVYSKEEAIIIEKGKGSYLYDT
                     NGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEI
                     TPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNYGYHGDTIGAV
                     SVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIA
                     GFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHED
                     VQPDIMCLGKAITGGYLPLAVTLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVA
                     LENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKT
                     PLEIEKVERIVRNCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDR
                     KC"
     gene            complement(6749..7435)
                     /gene="bioD"
                     /locus_tag="RPH49_002466"
     CDS             complement(6749..7435)
                     /gene="bioD"
                     /locus_tag="RPH49_002466"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dethiobiotin synthase"
                     /protein_id="HDY5125583.1"
                     /translation="MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCVFKPFQTEERQ
                     DGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMADQIFLNKQRVLDKVKVLDK
                     EFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDY
                     VNQNVSASNFLIMNRYTDSYIEKDNQMTIGKLTNKTVYTFEEHATYENFSEAFLKQLI
                     GVKNELHTTT"
     gene            complement(7490..7657)
                     /locus_tag="RPH49_002467"
     CDS             complement(7490..7657)
                     /locus_tag="RPH49_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125584.1"
                     /translation="MQLLILTDIFYRIAVYICPNSVRSLSHFNSKVKILPKFIVILRS
                     LNSCFLEKHAP"
     gene            complement(7823..8163)
                     /locus_tag="RPH49_002468"
                     /pseudo
     CDS             complement(7823..8163)
                     /locus_tag="RPH49_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2747 a         1476 c         1150 g         2790 t
ORIGIN      
        1 ggttaaatcg aacggaatta tgacattttt aaagccattg taaaaaaagt tgataatggt
       61 caattgttaa tgaacagtta attataataa cgttcaaaat atattattat ttaattaagt
      121 taaataaaat tatagaaaga aagtgaaact tatgcttaaa aataaaatat tagctacaac
      181 tatatctgta agcttacttg cccctcttgc caatccgtta ttagaaaatg ctaaagctgc
      241 caatgatact gaagacatcg gtaaaggaaa cgatgtagaa attatcaaaa ggacagaaga
      301 taaaacaagt aataaatggg gagtgactca aaatatccaa ttcgactttg tgaaggataa
      361 aaaatataac aaagatgctt tgatcctaaa gatgcaagga ttcattagct ctcgaacaac
      421 atattataac tataaaaata caaatcatat taaatctatg cgttggccct tccaatataa
      481 tattgggtta aaaacaaatg atccaaatgt ttctttaatc aattatttac cgaaaaataa
      541 aattgaatct acaaatgtga gccagacatt aggatacaat atcggcggta atttccaatc
      601 agccccatca ctcggtggta atggatcctt taactactct aaatcgatta gctatacaca
      661 acaaaattat gtcagtgaag tggaacaaca aaactcaaaa agtgttttat ggggtgtcaa
      721 agcgaattca ttcgtcactg catcaggtca aaagtcagca tttgatagtg atttattcgt
      781 aggatacaaa ccaaatagca aagatccaag agattatttt gttccagaca gcgaattacc
      841 acctcttgtg caaagtggat ttaacccttc atttatcgca acagtatctc atgaaaaagg
      901 ttcaggcgac acgagcgaat ttgaaatcac ttatggaaga aatatggatg tcactcatgc
      961 cattaaaaga tcaacacatt atggcaacag ttatttagat ggtcacagag tccataatgc
     1021 atttaaaaat agaaactaca ctgtgaaata tgaagtcaat tggaagacac acgaaatcaa
     1081 agtgaaagga cagaattgat atgaacatga ataaattagt caaatcatcc gttgctacat
     1141 ctatggcatt attattactt tctggtactg ctaatgctga aggcaaaatc acaccagtta
     1201 gcgtcaaaaa agtagatgat aaagttactt tatacaaaac tacagctaca gcagattcag
     1261 ataaattcaa aatttcacag attttaacat ttaatttcat caaagataaa agttatgata
     1321 aagatacttt agtacttaaa gctgcaggta atattaactc aggttatgaa agaccaaacc
     1381 ctaaagacta tgacttttca aaaatatatt ggggtgcaaa atacaatgtg tctatcagtt
     1441 cacaatctaa tgattcggtt aatgtagtag actatgcacc taaaaatcaa aatgaagaat
     1501 ttcaagtgca aaacacttta ggatacacat ttggtggtga catcagtatc tctaatggtt
     1561 tatctggtgg acttaacgga aacactgctt tttctgaaac aattaactac aaacaagaaa
     1621 gttacagaac aactttaagt cgcaacacaa attataaaaa tgtcggttgg ggtgtagaag
     1681 cacataaaat tatgaataat ggttggggcc cctatggccg agatagcttc catccaacat
     1741 atggcaatga aatcttctta gctggtagac aaagcagttc atatgcaggc caaaacttca
     1801 tagcgcaaca ccaaatgcca ttattatcta gaagtaactt caatccagaa tttttaagcg
     1861 tactatcaca cagacaagat ggcgctaaaa aatctaaaat tacagtaact tatcaacgtg
     1921 aaatggattt ataccaaatt cgttggaatg ggttctactg ggcaggcgca aattataaaa
     1981 actttaaaac tagaacattt aaatcaacat atgaaattga ttgggaaaat cacaaagtga
     2041 aattgttagg tacaaaagaa actgaaaaca ataaatagct agtaaaacac ggtcgccaac
     2101 aataattgtg acgaccgtgt tttgatttat tatcttagta agactgccat tctttttctc
     2161 aatgtgagat ataaaggaat agctacaatt aaagtgaata ttacgcctgg aatcgcgttt
     2221 aataacacta cccacacagg taaatttaaa ataatagata atagtagcct agataccaaa
     2281 ctgcctaata cacttgctaa aactaatgat agtacattta ttttcaataa ataaacaact
     2341 gcaatagcta taactctaaa tataatagag ataatcacat taattggatt aaatacacca
     2401 aatactagta ataataggct agataataat ccacctaaaa agtacttttt aattccaaag
     2461 aaagctaata tcaataatgc tgccggtgca gataattgaa aatctaaacc tggtataatg
     2521 gatggtattt tcaaaactgc caaaatggtt aaaatcgcag caatgacact aatttgagta
     2581 atatcttttg atgtcatact aaaaccccta taccgtttca taaacaactt gcttcggtgt
     2641 gctttctaaa aatgatatgt aatgatttaa atcaatacga tcgtccacaa atattattct
     2701 gcctccatat ctcgtattaa ctggtttaat atcaaataat cgatggtaac caattttagc
     2761 agaggcaaaa taacctgtcg tatacgttaa gtcatcggac acacaaagtt ctcctttgac
     2821 atatggatgc gcattgatac aactagcaat tgctaaggca tcagtcactc tttcattaag
     2881 atcaccttta ttatttatat cttcaaacga aaaatgcgtt gccctaatcc ctctttgtcc
     2941 aaatgaatct aaacgtttac cagatatagc agatagaata atagctcctg tataaaccgt
     3001 ttcattttta atatatgtca tcccttgatt tagcgcttgt tcagtgacac cacattcttg
     3061 tgttaaatgt tggagatttg ctttatcatc ctcagtaatt tgtaatgctt ttatttgttg
     3121 aatcggttcc atgatttttt gtatttttat attgagaaaa tccggttgcc cattttcatg
     3181 aaaaaaacct ttattataaa accttcgtac cgtctgttct attttgtcaa actcacaaat
     3241 cgtttcagca ccactaatat gaacatcttg attgctagaa cgcattttta tactatacat
     3301 gacgatcacc tcaatcttct tgatgcaaaa tttcaaacaa cctatctaca tcttgttcag
     3361 tatgaaaata cgacaatgat attcttaaca ttggcttagt cacagttgga taccttaaat
     3421 aacttgtaaa cacatgatgc tttaataatg tttgatgaat gttcttagcc gcttctatgt
     3481 catcaaactc aataaactta atcggcgagt ttgaactatt ataattaaca ttgagtgttt
     3541 ttaacttttg gttaaaatat ttaatcaaac tatttaattt agtgcgtcta tcatcagcat
     3601 ttattaactt ttcaatattt ctttttataa aatacaaatt ataaattggc aaactacttg
     3661 agtagatgag tggtctaccg tgattaatta acatatcctt cacatcattt gaacttaaaa
     3721 tcacaccccc gtatgcacca catgctttag ataaactaga agtgagtata tctatgcctt
     3781 gataattcga gtaattctct attccaaaac tatgtgaaac atcgagtatc agtgttgcgt
     3841 tatatttatg ctttaatgag actaattgac caatgtccac aacgtcgcca ttcgttgaaa
     3901 atacactatc agatatgatt attttttgta tattttgatt agggtattcc gctaaccttt
     3961 tttctaaatc agcaatatct agatgcttat atatcacttt ttctaaacca cttaacttaa
     4021 taccgtcaat aatactcgca tgattttctt gatctgaaaa cacgacacaa tttgtatttt
     4081 tgaaaatatt aaataacgcc aaattagcat cataaccact atttaagata gtacatgcat
     4141 tatatccgag ccaacctgct aacattgttt caatctcttc ataagctgtc gaacttccac
     4201 taattaatct tgaacttgat aagtgataac tatacttccg cataaatctt tcgaaatcat
     4261 ccttatcaaa cgctatttgt cctaatccta aataatcatt agatgtatag ttcgtacatc
     4321 gcttattttc tacttcaata tactgtctat ctatataccc taccgattta agcgaccgat
     4381 ataacccttt ctgttgtaat aaatcaattt gctcttgaaa catcattctt gttttcctta
     4441 ttttcacaag tgtcataatc aatttcaaag cccaaatcat taatcatatc gtagtctaat
     4501 tggttcggtt gcccaccagt aattagataa tcaccgacaa atattgaatt cgccgctttt
     4561 aatgctaatg gctgtaacga acgtaagttg acctctcttc ctccagcaat acgaatttct
     4621 ttcgtaggat tgattaatcg gaataatgct acgattctta aacatttcat tggtgttaaa
     4681 tcatccatgc taccgaactt tgtaccttta attggatgta aaaaattaat cggaatactg
     4741 tcggcatcca tttctttcaa agcaaatgcc atatcaacaa tatcttgatt agattctccc
     4801 ataccacaaa tcacgccaga acatggtgat atattattcg ctttcattag ttctatcgta
     4861 tctgttctat ctttataact atgcgttgtc acgacgttat catggtaatt ttcacttgta
     4921 ttaatattgt ggttatatct gtctacacca gcagacttaa gtttcttagc ttgttcgtca
     4981 ttcgttaatc ctaaacatgc acatattttt agttgcgggt gttgagattt aatcgttctt
     5041 acagtgttac taatatgatc aacttcttta tcgctcggcc ctctaccact cataacaata
     5101 caatatgttc caatatgatt atcatgtgct acctttgctc catcgataat ttgttcctct
     5161 ggaattaaag catatcgctg tttttgttta atatctcgtg attgtccaca gtacccacaa
     5221 ttctcaggac atataccact tttagcattt aaaatcatat ttaattttac ttttttaccg
     5281 aaataatgtt ttcttaaaat gtacgcctca tttaataaat ctaaggtatc aatattagta
     5341 tcctcataaa ttttcaatac agtctctttt gttaattgtt ccccttgtaa tatgcgttta
     5401 gccaaattca tattaacact tcctatctaa aatgttatgt actgcctttt taaaaatacg
     5461 taccatcgtt ttcacttctt tatttgacat acttaacact ggcacaaacg taatgacatt
     5521 ttctaaattt ctaatcatta gcccattttc tttacaatta cgtacaatac gttcaacttt
     5581 ttcaatttct aacggcgttt tactatcttt atctgtaacc aattcaactc caaacattaa
     5641 gcctcgtcct cttacatcac caacatttcg atgacgcttc agcgcatgta actgtttctc
     5701 aagtgttgat gatgtcgttt caatatgtga caataactta cgtttttcat aaagtcttat
     5761 attttctaat gcaaccgtac aaacgatttg atttccggtg tatgtatgac catggaaaaa
     5821 ggtattcaca ccatgcgaat cacttaaaaa tgcattgtat attttttgag atgtcaatgt
     5881 aactgcaagt ggtaagtagc cacctgtaat cgccttacct aaacacataa tatccggttg
     5941 aacatcttca tgattacatg caaacatctt tccagttctc ccaaaaccaa cagctacctc
     6001 atcacaaatt aataagacat cgtatttttt gcacaatttc tcgacttctt tcaaaaagcc
     6061 tttaggatga acaaacaagc ctgtcgcacc ttgaatcaac ggttccaata taaaccctgc
     6121 gatttcatca tttctttcaa ttagaatttg ctctatattc gttaaaatag ctgtcatcat
     6181 ttcattttca gtatcgtaat tactgcgata gaaagatggg ctttctactt gaatattctc
     6241 aaatattaag tctttaaata ttttatgaaa ggtcttgata ccaccaacac ttaccgcacc
     6301 aatcgtatcc ccatgataac cgtaatttag cgttataaac ttgtttttct tggcatattt
     6361 ttctctatca atatttttcc aatactgata tgccatcttt attgcgattt caacagacgc
     6421 actgcctgta tcagaataaa atacttttct tagattactt ggcgtgattt cgattaattt
     6481 ttccgcaagt tctattgacg gaatatttga tgatcctagc agcgtagaat gggcaatttt
     6541 attgagttgc tttttaatta ccttatttaa gtatttatta ttatgaccat gcacattgac
     6601 ccacaacgat gcataaccat ctaaatattt attgccattc gtatcgtaaa ggtagctacc
     6661 ctttcctttt tcaatgatga ttgcttcttc tttgctatat acacccattt gtgtaaatgg
     6721 atgccaaaca tattctgagt ctttttgttt aagttgttgt gtgtaattca tttttaactc
     6781 ctattaattg ttttaaaaat gcttctgaga aattttcata cgtggcatgt tcttcaaatg
     6841 tatagactgt tttatttgtt aattttccaa tcgtcatttg attgtctttt tcaatatagc
     6901 tgtctgtata gcgattcatt attaaaaaat tactcgctga tacattctga ttaacataat
     6961 cttggtgaac aatggcatcg ctaatagcac ctaattttga tggcaacaca ctgatgacac
     7021 aatctgcaca atcattgatt agatctttag tcatgtagaa atcatctgta ccttcatata
     7081 ttggtacggc aattccccca gccccctcaa ttaagataaa atcaaattcc ttatctaaaa
     7141 cttttacctt atctaataca cgctgcttat ttagaaaaat ttgatctgcc attttaaatg
     7201 caaggtgtgg tgatacaggt tgcttaaaag tataaagtga cgttatgtca tagcttaaat
     7261 cacattcatt tttaaatact tctaaatctg gaaatgtccc gtcttggcgt tcctcagttt
     7321 gaaatggttt aaaaacacaa acacgatgac cacgtgtttt caaagcatgg tataaatgct
     7381 ttgtaacata ggttttgcct acatcagtat tcgtacttgt aataaaaatc ctcataaaaa
     7441 ataagcacct caatccgaat gtaaactttt ataattaata agtttacatt taaggcgcat
     7501 gtttttcaag aaaacatgaa tttaaacttc tcagtataac tataaatttt ggcaaaattt
     7561 tgaccttgct attgaaatga ctaaggcttc ttacggaatt cgggcagata taaacagcga
     7621 ttcgataaaa tatgtcagtt aaaattaata attgcattat ttcttaataa aaagacatcc
     7681 tagctttacc atgttgtgaa acaatccatt aattgtaata ttacgttgag cgccttgttc
     7741 atcaatgata taattagtta cataataaat tgaacatcta aatacaccaa atcccctcac
     7801 tattgcccta gtgaggggat ttatactccg gtaaataacc gaaggtattt tgaatcattg
     7861 ttaaaaatgg aattaaagtt ctagtatctg tcgggttttg aaataggtca taggataaaa
     7921 caaattgaga atttgtcgct atttgtaaat tgtatcctgg cttaagttgg ccgtttttca
     7981 tatagtcttc cttcattctc ataaaagttg catcatgatc agttttagaa aagctatttc
     8041 tatctttaag aatcgatttt tgttcttcat atttactttt tctttcggaa taatcatcaa
     8101 atttcttttt gaacttctta atctcagttc tttttttacg ggtctgtttt ctaatttgag
     8161 cac
//
LOCUS       DAPSKH010000088         7616 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPSKH010000088 DAPSKH010000000
VERSION     DAPSKH010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7616
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.088"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            10..855
                     /locus_tag="RPH49_002469"
     CDS             10..855
                     /locus_tag="RPH49_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5125585.1"
                     /translation="MKQLVGIPESMLIPLIARAKEYENEKPIIKDALSKKIFDGLDDM
                     YKNVTCDDMSQIGISIRTVIIDCVTKRLIKDNKDLIVVNIGCGLDTRFQRFNKEKISW
                     IDLDVPESIEIRKTFFKESNSYKMISKSMLDYSWIDDVKNYKFFNSKSDILFIIEGVL
                     MYFDESVMTQLLDTIIKKMGDHNLTFAIEFCSKTIANNTKRHQSVSKLSSQPVFKYGY
                     NDLKKLNEILPNTIRVIHEYNYFDYYKNRWGLFGYCRFIPYLKKRLNNKIVLMKYKVP
                     KRQRH"
     gene            complement(1227..2450)
                     /locus_tag="RPH49_002470"
     CDS             complement(1227..2450)
                     /locus_tag="RPH49_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDY5125586.1"
                     /translation="MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLTDLFDKYDIKS
                     EILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRG
                     TTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDG
                     LIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSE
                     LKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLE
                     FNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVAS
                     SYVEQDDIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKY
                     IDIFKEASIQYLKEK"
     gene            2885..3937
                     /gene="lukH"
                     /locus_tag="RPH49_002471"
     CDS             2885..3937
                     /gene="lukH"
                     /locus_tag="RPH49_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukGH subunit H"
                     /protein_id="HDY5125587.1"
                     /translation="MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVD
                     KSQQKEKRNVTNKDKNSTAPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYD
                     KNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNPKTEILDQLPKNK
                     ISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHW
                     SVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLT
                     YLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKEGQRLIVTYEVDWKNKT
                     VKVVDKYSDNKSFREG"
     gene            3959..4975
                     /gene="lukG"
                     /locus_tag="RPH49_002472"
     CDS             3959..4975
                     /gene="lukG"
                     /locus_tag="RPH49_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bi-component leukocidin LukGH subunit G"
                     /protein_id="HDY5125588.1"
                     /translation="MIKQLYKNITICTLALSTTFTVLPATSYAKINSEIKAVSEKNLD
                     GDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGY
                     WNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGG
                     LTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAYLINNMGHDHTRQLTND
                     SDNRTKSEIFSLTRNGNLWAKDNFTPKNKMPVTVSEGFNPEFLAVMSHDKKDEGKSKF
                     VVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHNVKFVKVLND
                     NEKK"
     gene            complement(5213..6043)
                     /gene="sph"
                     /locus_tag="RPH49_002473"
                     /pseudo
     CDS             complement(5213..6043)
                     /gene="sph"
                     /locus_tag="RPH49_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239616.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sphingomyelin phosphodiesterase"
     gene            complement(6094..7131)
                     /locus_tag="RPH49_002474"
     CDS             complement(6094..7131)
                     /locus_tag="RPH49_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDY5125589.1"
                     /translation="MKTRCYDGKKWQYEFKHEGKRYRKKGFRTKREANSAGLDKLNEL
                     RSGFNIDNYITLAEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINR
                     QVYQKFINDYSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSE
                     QEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFI
                     DERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSAC
                     RVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEE
                     DKKTTKILESM"
     gene            7239..>7616
                     /locus_tag="RPH49_002475"
     CDS             7239..>7616
                     /locus_tag="RPH49_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDY5125590.1"
                     /translation="MTQFLGALLLTGVLGYIPYKYLTMIGLVSEKNKIINTPVLLIFS
                     IETCLIWFYTFIIFNNVDLKNLSLLQLLTGLKANIWFLIIFVLTVLVFNPLIVKFIIW
                     LINETRKFMNLDCISLLDKRDKLF"
BASE COUNT         2660 a         1088 c         1207 g         2661 t
ORIGIN      
        1 agtgattaaa tgaagcaact ggttggaatt cccgaatcaa tgttaattcc tttgatagct
       61 cgagcaaaag agtacgaaaa cgaaaaacca ataataaaag acgcactatc taaaaaaata
      121 tttgatggtt tagatgatat gtacaaaaat gttacatgtg atgacatgtc tcaaattgga
      181 attagtatac gtactgtgat aatagattgt gttactaaga ggcttatcaa ggataataaa
      241 gatttaatcg tggtcaatat aggttgtggc ttagatacaa ggtttcaaag atttaataaa
      301 gaaaaaatat catggataga tttagatgta ccagaatcaa tagaaatacg aaaaacattt
      361 tttaaagaaa gtaatagtta taagatgata tctaaatcta tgctagatta cagttggatt
      421 gatgatgtca aaaattataa attttttaat agtaagtcag atatattgtt tattattgaa
      481 ggtgtattga tgtattttga tgagagtgta atgactcaat tattggacac tattatcaaa
      541 aagatgggag atcataattt gacatttgcg attgaatttt gctcaaaaac aattgcgaat
      601 aatacaaaga gacatcaatc ggtatcaaag ttatcctcac aacctgtttt taaatatggt
      661 tacaatgatt taaaaaaatt gaatgaaatt ttaccaaata caataagagt aatacatgaa
      721 tataattatt ttgactatta taagaatcga tggggcttat ttggatattg tagatttata
      781 ccttatttaa aaaaaaggtt aaacaataaa atagtactta tgaaatataa agttccaaag
      841 agacagagac attaagttct tagacaatgt aaaaaagctg atttctataa attatttgat
      901 agaaatcagc ttttttcaaa tgtatttgat aatttacagc tcgttgagct gctgttttct
      961 agggatttat gtcccattcc ttttacgaga aggtttttac gagttttatg taactattag
     1021 aagctatctt tttatatgac cattagtcaa tatatgtatg acaaatcagc acaataattt
     1081 cagttttaca tcacttaatc aatgaaaatg tgcttgttga tatttgaata tttacattca
     1141 aacaatattc atcgttattt ctatcaactt aaaattcgca ataaaaaact gccagcacgc
     1201 gaatagggca gctgacagca tcgttcttat ttctctttta aatattgaat ggaagcttct
     1261 ttaaaaatat caatatattt cagatacata tctttttcaa tatattcatc gatttgatgt
     1321 gccattaatg gattacctgg tccaaaaatg gctaaatcaa cattgtcctt attatcacct
     1381 aagaaactag aggcatctgt tgcacctaca agcgccgaaa caaatatatc gtcttgttct
     1441 acataactag aagctacatc tttaatcgta gtaattaatt tgctattttt atcgcttgtt
     1501 acaggtcggt gattgcttgg aatatcgagt gaaagcttat tgctatccac atcattaatg
     1561 atattttgga aaaacgattc tataaagtcg ttatcatact caggaactgg tcttacgtta
     1621 aattcaagtg aagcttcatc tggtacagag ttaaattgtt tgccgccatt tataatcgaa
     1681 catacagctg taagaccaga tgcataattt gcatcctctt cagaaatttc ttttcctatc
     1741 aatgatttga acatgggtgc aacatctaat tcatgtttag tatcatgttt tttaagctct
     1801 gaatattttt ctttaaattg attataaaat tcaagcagtg tatcaattgc attgtcacca
     1861 ataaatggaa ctgagctatg gacagctttg ccagttgcag ttactttaca tgacatagac
     1921 cctttatgtg cataataaat tccagatcca gttggttcag caataattaa gccatctaca
     1981 tcgtctaaat agcctttatc agccaataat ttggcacctt cttgttcttt ctcttcgcca
     2041 gcagtagcta gtaatcttat cgttccttga ggcaattgat tttgttcttt taattcaatg
     2101 agtgtgatga ccaaagccat cagaccgcct ttcatatccg ttgtgcctcg accgtataat
     2161 ttgccagctt tttctgtgag ttgaaaaggg ggataagtcc aattatcttg atttcctgca
     2221 tcaacaacat ccatatgacc actcaatgcg agtataggtg agccgttacc gatttctgca
     2281 acgatattgg cgcggtgttc attaactttc aaaatttcag atttaatatc atacttgtcg
     2341 aataaatctg ttaaataatt acaaacgtct atttcattat tattttcagt ttgtagttca
     2401 acaatatctg ctagtaattg aattttttct ttttcactaa aagttgtcat taagctcaca
     2461 cctttcaaag tagtatatat atttatataa acataatttt tattcttaaa cataatttaa
     2521 aatgcagaaa gtagtgtgtt atttgatttc gttctatgaa attaactgtc tagtatcaac
     2581 gatcttatta acgctgatat cggatatgct taattttata gtaaattgta tgagaaagat
     2641 gcaggatatt atttagctaa taattatata taaatttcaa atcgatggtt attaactact
     2701 aaataaaaat atttgctaaa ttaatgactt tgtacacaca ttatttttaa agaggataaa
     2761 gtatttaata atattaacaa aatcatttaa taaatagtta aatatatatt ctctgttttt
     2821 gtgatattat tcacatgtcg atacatatca acaaatatca atcatacgaa agaaggttat
     2881 aacaatgaaa aataaaaaac gtgttttaat agcgtcatca ttatcatgtg caattttatt
     2941 gttatcagca gcaacgactc aagcaaattc agctcataaa gactcgcaag accaaaataa
     3001 gaaagaacat gttgataagt ctcaacaaaa agagaaacgt aatgttacta ataaagataa
     3061 aaattcaaca gcaccggatg atattgggaa aaacggtaaa atcacaaaac gaactgaaac
     3121 agtatatgat gagaaaacaa atatactcca aaatttacaa ttcgacttta tcgatgatcc
     3181 aacttatgac aagaatgtat tacttgttaa aaaacaaggc tcaattcatt caaatttaaa
     3241 gtttgaatct cataaagaag aaaaaaattc aaattggtta aagtatccaa gtgagtacca
     3301 tgtagatttt caagtaaaaa gaaatcctaa aactgaaata ttagaccaat tgccgaaaaa
     3361 taaaatttca actgcgaaag tagacagtac attttcatat agctcaggtg gtaaattcga
     3421 ttcaacgaaa ggtattggac gaacttcatc aaatagctac tccaaaacga ttagttataa
     3481 tcagcaaaat tatgacacaa ttgccagcgg taaaaataat aactggcatg tacactggtc
     3541 agttattgcg aatgacttga agtatggtgg agaagtgaaa aatagaaatg atgaattatt
     3601 attctataga aatacgagaa ttgctactgt tgaaaaccct gaactaagct ttgcttcaaa
     3661 atatagatac ccagcattag taagaagtgg ctttaatcca gaatttttaa cttatttatc
     3721 taatgaaaag tcaaatgaga aaacgcaatt tgaagtaaca tacacacgaa atcaagatat
     3781 tttgaaaaac agacctggaa tacattatgc acctccaatt ttagaaaaaa ataaagaagg
     3841 tcaaagatta attgtcactt atgaagttga ttggaaaaat aaaacagtta aagtcgttga
     3901 taaatactct gataataaat catttagaga aggataaaat cgaagggaag gattacaaat
     3961 gattaaacaa ctatataaaa atatcacaat ttgtacgtta gcactatcga ctactttcac
     4021 tgtattacca gctacttctt atgcaaaaat taattctgaa attaaagctg tttctgagaa
     4081 gaatcttgat ggtgatacta aaatgtatac acgtacagct acaacaagtg atagtcaaaa
     4141 aaatattact caaagcttac aatttaactt cttaactgaa cctaattatg ataaagaaac
     4201 agtatttatt aaagcgaaag gaacaatagg tagtggttta agaattctag acccaaatgg
     4261 ttattggaat agtacattaa gatggcctgg atcttattca gtttcaattc aaaatgttga
     4321 tgacaacaat aatacaaatg tgactgattt tgcaccaaaa aatcaggatg aatcaagaga
     4381 agttaaatat acgtatggtt ataaaacagg tggagatttt tcgattaatc gtggagggtt
     4441 aactggaaat attacaaaag agagtaatta ttcagagacg attagttatc aacaaccatc
     4501 gtatcgtaca ttacttgatc aatctacgtc acataaaggt gtaggttgga aagtagaagc
     4561 atatttgata aataatatgg gacatgacca tacgagacaa ttaactaatg atagtgataa
     4621 tagaactaaa agtgaaatct tttctttaac acgaaatgga aatttatggg cgaaagataa
     4681 ttttacgcct aagaataaga tgcctgtaac tgtttctgaa gggtttaatc cagaattttt
     4741 agctgttatg tcacatgata aaaaagatga aggtaaatca aaatttgttg ttcattataa
     4801 aagatcaatg gatgagttta aaatagattg gaatcgtcat ggtttctggg gctattggtc
     4861 tggtgaaaac catgtagata aaaaagaaga aaaattatca gcattatatg aagttgattg
     4921 gaagacacat aatgtgaagt ttgtaaaagt acttaatgat aatgaaaaga aataagtaat
     4981 aaaagttgcc tgctacatag aatgtagtag gtaactttta tttatatttg agtagataga
     5041 tttattatga tgtgcagtgt atgaatcttg tttgagtgta gagtaaagac ttgtattaat
     5101 gaaaaattaa aattgttaag atgattttat taaaatgtaa gtcaattcaa attttaacaa
     5161 tataactcgc ttcgaccttt tagaacgaag cgagttatta gttagttgag cactatttac
     5221 tataggcttt gattggataa tgatctgaaa aatcattgta aacgtagtaa tatgggaacg
     5281 catatacatc ccatggctta ggtttttcag tcacaacttc attgactaat tgttttggtt
     5341 gtttatgatc tttatctgta aatatatagt ctaaatgttc tggtttacca ttagggtaat
     5401 tatatttcgc aattgaattt gattgagggt cccatgtgct attatgacct gcatatagaa
     5461 catcatttac attcaagttt ttaagcatat ctttgaactc tggagtgcct ttattaacat
     5521 taaggtcgcc accgatatat accgtttcat ctttagggat atttttcttt ttaacaaagt
     5581 cactgatttc tttcatttgt tcagctctaa tttttctatc atgtccagca ccacaacgtg
     5641 aatcttcaga ttgtgtatgt gtaccgataa cgtgaacgtt cttaccgttt ttctctattt
     5701 ttgtataaac aaagcctttg ttgctatcat tatcgaatcc acaaccgctt ttgaaaacat
     5761 gctggatttt ttctttaata ggatatttac ttacaatcgc tacgccacca tcttctgcaa
     5821 cagttgatga gtagctacct tcagttttgt cccaccctga ttgagaacga ccgagtacag
     5881 gtgtttgata aggatattct ttttttacat tacttaataa tttatctgat gcgccattat
     5941 caaatgcttc attgaatatt acgacatcat tatttttaat ataagaagat tgtccgatta
     6001 aatcagcgcg tttatattgc ccccagtttg gatacataga aaccttgtaa caacagtatt
     6061 tattgggttt ggagtcccta atgggtccct aaattacata ctttctaaaa ttttagttgt
     6121 ttttttgtcc tcttcattaa atttttcttc taacaaatga gaatacacgg atgtagttat
     6181 tgctatattt ttatgaccta atcttttaga aatgtaatgt atagatacac cttttgctag
     6241 taaataagaa caatgagtgt gtcttaatgc gtgcgatgta ataattggta tattattgac
     6301 tctacaggct gatttcaaag cattattgat agcctgaagg ttaattatag atccggcttc
     6361 tttgaaaatg taaccatcat agctaattgc aaatgtactt atgacgtcca taatgtgttt
     6421 catatcagat ttagcgatac tgatatatct aggggaagta tcggtttttc gctcgtcaat
     6481 aaatatagtg tttttcactt ggttgatatg ctcaatcttt atatttcttg caccactgac
     6541 acgacaaccc gtacaaatca ttatgaatag cgctaatgat gaacgagttc tcttctttct
     6601 gacgtgatct tttagtattt catattcagt taccgagatg aatttttctt gttctgactt
     6661 cgtaggtttt ccggctttat aattaacttt ataagcgggg tttttaaaaa taagtccatc
     6721 atataatgcg tcatctaaag ctgaccgaat agcaccgttt gtttttctta tagtttcttt
     6781 tgcgtgttct tttgaatagt cgtttatgaa tttctgataa acttgtctat ttatctttga
     6841 taactccatt ttacctattt tatgtttttg tatatgttgt aatgcatttc tataatgacg
     6901 gtaggtattt tctttaacaa caggttgttt atatgtttta atccaatttt cgaagtattc
     6961 tgcaagagtt atatagttat ctatattaaa accacttctt aactcattta acttgtctag
     7021 tccagcagaa ttagcttcac gctttgttct aaaacctttc ttacggtatc tttttccttc
     7081 atgcttaaat tcatattgcc attttttacc atcgtaacaa cgtgttttca tacgttccct
     7141 cctcaaaatt ggcaaaaaat aataagggta ggcgggctac ccaaaattta gtactaggta
     7201 ctaaatatgt tataataaaa taaaaagtag gtgataagat gactcaattt ctaggggcgc
     7261 ttcttcttac aggagtttta ggttacatac catataaata tctaacaatg ataggtttag
     7321 ttagtgaaaa aaacaagatt atcaatactc ctgtattatt gattttttct attgaaacat
     7381 gtttgatatg gttttatact tttataattt ttaataatgt tgatttaaaa aatttgagtt
     7441 tacttcagtt gcttacaggt ctaaaagcaa atatttggtt tctaattatt tttgttttaa
     7501 cagtgcttgt atttaatcct ttaattgtta aattcattat ctggttaatt aatgaaacaa
     7561 gaaagtttat gaatttggat tgtataagct tattagacaa aagagacaag ttgttt
//
LOCUS       DAPSKH010000089         7605 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPSKH010000089 DAPSKH010000000
VERSION     DAPSKH010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7605
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.089"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            322..1623
                     /locus_tag="RPH49_002476"
     CDS             322..1623
                     /locus_tag="RPH49_002476"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDY5125591.1"
                     /translation="MRMIDIIEKKRDGHTLTTEEINFFIDGYVKGDIPDYQASSLAMA
                     IYFQDMNDDERAALTMAMVNSGDMIDLSDIKGVKVDKHSTGGVGDTTTLVLAPLVAAV
                     DVPVAKMSGRGLGHTGGTIDKLEAIDGFHVEIDEATFVKLVNENKVAVVGQSGNLTPA
                     DKKLYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGSGAFMKTLEDAEALA
                     HAMVRIGNNVGRNTMAIISDMNQPLGRAIGNALELQEAIDTLKGHGPKDLTELVLTLG
                     SQMVVLANKAETLEEARALLIEAIDSGAALEKFKTFIKNQGGDETVIDHPERLPQAQY
                     QIEYKAKKSGYVTELVSNDIGVASMMLGAGRLTKEDDIDLAVGIVLNKKIGDKVEEGE
                     SLLTIHSNRQDVDDVVKKLDSSITIADHVVSPTLIHKIITE"
     gene            1637..1987
                     /locus_tag="RPH49_002477"
     CDS             1637..1987
                     /locus_tag="RPH49_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125592.1"
                     /translation="MNILRYLLGIGFSVIGVLHFTRERQFRNIIPKCLPLRKTAVLVT
                     GIFEILFGLALLIKRPSQCLKNTINLFLLAVFPANIYMAVKKLPLGDKQLPTWQLYLR
                     LPMQFVLMGLIKKL"
     gene            complement(2139..2609)
                     /locus_tag="RPH49_002478"
     CDS             complement(2139..2609)
                     /locus_tag="RPH49_002478"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDY5125593.1"
                     /translation="MTKMNVESFNLDHTKVVAPFIRLAGTMEGLNGDVIHKYDIRFKQ
                     PNKEHMDMPGLHSLEHLMAENIRNHSDKVVDLSPMGCQTGFYVSFINHDNYDDVLNIV
                     EATLNDVLKATEVPACNEVQCGWAASHSLEGAKTIAQAFLDKRNEWHDVFGTGK"
     gene            2920..4104
                     /locus_tag="RPH49_002479"
     CDS             2920..4104
                     /locus_tag="RPH49_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDY5125594.1"
                     /translation="MSEKQQILDYIETNKYSYIEISHRIHERPELGNEEIFASRTLID
                     RLKEHDFEIETEIAGHATGFIATYDSGLDGPAIGFLAEYDALPGLGHACGHNIIGTAS
                     VLGAIGLKQVIDQIGGKVVVLGCPAEEGGENGSAKASYVKAGVIDQIDIALMIHPGNE
                     TYKTIDTLAVDVLDVKFYGKSAHASENADEALNALDAMISYFNGVAQLRQHIKKDQRV
                     HGVILDGGKAANIIPDYTHARFYTRAMTRKELDILTEKVNQIARGAAIQTGCDYEFGP
                     IQNGVNEFIKTPKLDDLFAKYAEEVGEAVIDDDFGYGSTDTGNVSHVVPTIHPHIKIG
                     SRNLVGHTHRFREAAASVHGDEALIKGAKIMALMGLELITNQDVYQDIIEEHAHLKGN
                     GK"
     gene            4104..5297
                     /locus_tag="RPH49_002480"
     CDS             4104..5297
                     /locus_tag="RPH49_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HDY5125595.1"
                     /translation="MTNNGNEPNLTLSDLYDKDVVYTSRPSYISNPWLKPDEHQSNFL
                     TGRELLIANQLPVIVHEASATDKLHQLFQVIGKDVPNSIYTFNNQQSYENLIKQLAHK
                     ENKKIYFQYIHDETILNQQYYALDKTLFVALNNKARIPEWTNGKFLPKRKVVKIEQFE
                     NEIKNWEFPFVIKPGDDLPTAGGYGVMICYHDADLQKAITRIKEATAETNSLIIEQKI
                     EEKANYCVQFAYSESLGIQYLGAATQLTDKYGFYNGNENTTNVPEHVIEAGRQIMENG
                     VNQGFFGVAGFDLLVDEDDNVYAIDLNFRQNGSTSMLLLANELNSGYQKFYSYHSKGD
                     NTHFFNTILKYVKEGSLYPLSYYDGDWYGEDKVKSRFGCIWHGDSKETVLENERAFLA
                     ELEHY"
     gene            5696..6367
                     /locus_tag="RPH49_002481"
     CDS             5696..6367
                     /locus_tag="RPH49_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2750 domain-containing protein"
                     /protein_id="HDY5125596.1"
                     /translation="MSYKAYPFFRDILINECIYFASKNKKLVRLNYKSEAYVGVWTEE
                     SVAVSFLTSRDIPFDKVVKMDVDRFATYELDELFDEQDHIIMNQTMEEEGHLLNVVAV
                     TQEVMTELDKIRIKEFVQDVAKYDEVYGLTKKGSKQFILISENDSDEKKPHIMPVWSI
                     KNRALKVRDEDFEECDLITIEGSVFGEWLDELRDDHKAVAIDLKTGVVGTIVSAQKLS
                     NELTF"
     gene            complement(6497..7300)
                     /gene="coaW"
                     /locus_tag="RPH49_002482"
     CDS             complement(6497..7300)
                     /gene="coaW"
                     /locus_tag="RPH49_002482"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II pantothenate kinase"
                     /protein_id="HDY5125597.1"
                     /translation="MKVGIDAGGTLIKIVQEQDNQRTFKTELTKNIDQVVEWLNQQQI
                     EKLCLTGGNAGVIAENINIPAQIFVEFDAASQGLGILLKEQGHDLADYIFANVGTGTS
                     LHYFDGQSQRRVGGIGTGGGMIQGLGYLLSQITDYKQLTDMAQHGDRNTIDLKVRHIY
                     KDTEPPIPGDLTAANFGHVLHHLDADFTPSNKLAAVIGVVGEVVTTMAITVAREFKTE
                     NIVYIGSSFHNNALLRKVVEDYTVLRGCKPYYVENGAFSGAIGALYLGK"
BASE COUNT         2636 a         1068 c         1485 g         2416 t
ORIGIN      
        1 gttcaaatta tgcaaggttt agaagcagat tcagattact aattttataa aaaacatgta
       61 agcatgggac atcgtaacca tatataagta tgtcgatatc agctttaaga catcataaat
      121 gccatgatga ttctaagata atttaatagg gactttgacg ttataaccaa tctatttaag
      181 aataataaca tcgcatttaa attgtgatat taaaaatgaa atcgatagct tgctataata
      241 attttcgctt gtgcttttaa aaatggacta gagaaagcgc agatgctttg tcctaagctt
      301 tttaagaaaa ggatgataaa aatgagaatg atagacatta ttgagaaaaa gcgtgacggt
      361 catacgctaa caacggaaga aattaatttc tttattgacg gctatgttaa aggggatatt
      421 cctgattacc aagcatcaag tttagcaatg gcgatttatt tccaagatat gaatgatgat
      481 gagcgtgcag cattaacgat ggctatggtt aattctggtg atatgataga tttgagtgat
      541 atcaaaggtg tcaaagtaga taagcactca acaggtggtg taggagatac aactacgttg
      601 gttttagcac cattagtagc agctgtagat gttcctgttg caaaaatgag tgggcgtgga
      661 ttaggtcata caggtggtac gattgataaa ttagaagcaa ttgatggttt tcatgttgaa
      721 atagatgaag caacatttgt gaaattggtt aatgaaaata aagtggcagt tgtaggacaa
      781 tcaggaaatt taactcctgc agacaaaaaa ttatatgcct taagggatgt tactggtact
      841 gtcaattcaa taccattaat tgcctcttca attatgagta aaaagattgc tgctggtgca
      901 gatgcaattg tattagatgt aaaaactggt agcggtgcat ttatgaaaac attagaagat
      961 gctgaagcat tagcgcacgc aatggtacgt attggtaata atgtgggacg taatacgatg
     1021 gcgattattt ctgatatgaa tcagccactt ggacgtgcga ttggcaatgc gcttgagtta
     1081 caagaagcaa ttgatacgtt gaaaggacat ggtccgaaag atttaacaga acttgtacta
     1141 acattaggtt ctcaaatggt tgtacttgca aacaaagctg aaacgcttga agaagcgaga
     1201 gcattgctaa ttgaggcaat tgattcaggt gcagcattag aaaaattcaa aacatttatt
     1261 aaaaaccaag gtggcgacga aacagttatt gaccatccag agcgtttgcc acaagctcaa
     1321 tatcaaatcg aatataaagc taaaaaatca ggttatgtga ctgagttagt ctctaacgat
     1381 ataggtgtcg cttcgatgat gttaggagcg ggacgtttaa caaaagagga tgatattgat
     1441 ttagcggttg gtattgtttt aaataaaaaa attggtgata aagtagaaga aggagaatca
     1501 ttattaacga ttcacagtaa tcgccaagat gtagacgatg ttgttaaaaa attagattca
     1561 agcataacaa ttgctgatca tgttgtatcg cctacattaa ttcataaaat cattacagag
     1621 taggagttga agctgattga acatactaag atatttatta ggaataggtt ttagtgtaat
     1681 aggtgtattg cattttacac gagaacgaca atttagaaat atcataccga aatgtttgcc
     1741 acttcgaaaa acagcggttc ttgttacagg aatctttgag atattatttg gacttgcact
     1801 tttaattaaa agaccatctc aatgcttgaa aaatacaatc aatctattct tgctagctgt
     1861 attcccagct aatatctata tggcagttaa aaagttacct ttaggagata aacaattgcc
     1921 aacatggcaa ctatatttaa ggttacctat gcagttcgtg ttaatgggac taattaagaa
     1981 attatagtgg ttcttaaata aatcggacaa atgttaaaga ttttactttt tcatttgttc
     2041 gattttttga ctttgaagca taataaaaag cagttggaca atggcgattg taacatcatt
     2101 gttcgactgc ttttctgatt aacttgatcg actaagattt attttcctgt accgaaaaca
     2161 tcatgccatt cgtttcgttt gtctagaaat gcttgagcga tagttttagc accttctaat
     2221 gaatgacttg ctgcccagcc acattgtact tcattacaag caggcacttc agtagctttt
     2281 agcacatcat ttaaagttgc ttcaacaata tttaatacat catcataatt atcatgatta
     2341 ataaatgata catagaaacc agtttggcaa cccataggac ttaaatcaac aactttgtca
     2401 ctatgatttc taatattttc agccattaaa tgttctaatg aatgtagtcc gggcatatcc
     2461 atatgttctt tgtttggttg tttgaaacga atgtcgtatt tgtgaatgac atctccgttt
     2521 aatccttcca tcgttcccgc taatctaata aatggggcaa ccactttagt atgatctaaa
     2581 ttgaaacttt caacattcat ttttgtcatt ttgaatttcc tcctattaac tactcaaaac
     2641 tataaaacgc ttatgatttg ttgcattata aaacttaagt ttgttgtaag ttgtgtttct
     2701 aacaatactt aaattgtaac aatagggctt atgttttaca atttgaaact gttttataaa
     2761 tttatgaaag gcttttagtt attagaaaat tttgtaaata aagaaaaact agatgacatc
     2821 atgagataaa accgatagaa taagtaataa ttcattttga aagaacaaaa tattgtggat
     2881 gattaaaatg agtgtagggt aaaagggaga tagtaaaaaa tgagtgaaaa acaacaaatt
     2941 ctcgattata tagaaacaaa taaatatagt tatatcgaaa tcagtcatag aattcatgaa
     3001 cgtcctgaac ttggtaatga agaaatattt gcgtctcgaa ctttaataga tcgtttgaaa
     3061 gagcatgatt ttgaaattga aaccgagatt gctgggcatg caactgggtt tatagcgaca
     3121 tatgattcag gtcttgacgg gccagctata ggttttttag cagaatacga tgctttgcca
     3181 ggattgggtc atgcttgtgg tcataatatc attggaactg caagtgtgct tggtgcaatt
     3241 ggtttgaagc aagtgattga ccaaattggt ggtaaagtag tcgttcttgg atgtccagct
     3301 gaagaaggtg gggaaaatgg tagcgctaaa gcttcttatg tcaaggctgg tgtgattgat
     3361 caaatagaca ttgccttaat gattcatccg ggaaatgaaa cttataaaac gattgatact
     3421 ttggcagtgg atgttttaga tgttaaattt tacggaaaaa gtgctcatgc ctctgaaaat
     3481 gcagatgaag cgttaaatgc attagacgct atgattagtt attttaatgg tgtagcacaa
     3541 ctacgacaac atattaaaaa agatcaacgt gtgcatggtg tgattctaga tggcgggaaa
     3601 gcagctaata ttattccaga ctatacacat gctcgttttt atactagagc aatgacgcgt
     3661 aaagaattgg atatattaac agaaaaagta aatcaaatcg cacgtggagc tgcgatacag
     3721 actggttgtg attatgaatt tggtccaatt caaaacggtg tgaatgaatt cattaaaacg
     3781 ccgaaattag atgatttatt tgctaaatat gctgaagaag ttggtgaagc agttattgat
     3841 gatgattttg gttatggctc tacggataca gggaacgtaa gtcatgttgt gccaacaata
     3901 catcctcata ttaaaatagg atcacgtaat ttagtaggac atacgcatag atttagagaa
     3961 gcagctgcga gtgtacatgg tgatgaagca ttaattaaag gtgctaaaat aatggcgttg
     4021 atggggttag agttaattac aaatcaagac gtttatcaag acattattga agagcatgcg
     4081 catttgaaag ggaatgggaa gtaatgacaa ataatggtaa tgagccgaac ttaacgttaa
     4141 gtgatttata tgacaaagat gttgtctata cgtcaagacc ttcgtatata tcgaatccat
     4201 ggttgaaacc ggacgaacat caatctaatt ttttaactgg tagggagtta ttaatagcaa
     4261 atcaattacc tgttattgtt cacgaagcta gtgcgacaga taaattgcat cagctatttc
     4321 aagttattgg taaggatgta ccgaactcaa tttatacatt taacaatcag caatcttacg
     4381 aaaacttgat taaacaattg gcacataagg aaaataaaaa gatttatttt caatatattc
     4441 atgatgaaac aatcttgaat cagcaatatt atgcattaga taaaacgtta tttgttgctt
     4501 taaataataa agcaagaata cctgaatgga caaatgggaa gtttttacca aaaagaaaag
     4561 ttgtaaaaat tgagcaattc gaaaacgaga ttaagaattg ggaattcccg tttgtaatta
     4621 agccgggaga tgatcttccg acagcaggtg gctatggcgt tatgatttgt tatcatgatg
     4681 cagatttaca aaaagcgata acgcgtatta aagaggcaac tgctgaaacg aattcgctta
     4741 ttatcgaaca gaagattgaa gaaaaagcga attattgcgt tcagtttgca tactcggaat
     4801 cgctaggcat tcaatatctt ggtgcggcaa cgcaattaac ggataagtac ggattttata
     4861 acggaaatga aaatactact aatgtaccag agcacgttat agaagcaggt agacaaatta
     4921 tggaaaacgg tgtgaatcaa ggattctttg gtgtagctgg ttttgaccta ctcgtcgatg
     4981 aggatgataa cgtttatgcg attgatttaa actttagaca aaatggttca acgagcatgt
     5041 tattacttgc taatgagttg aattcaggat atcaaaagtt ttatagttat cattcaaaag
     5101 gtgataacac acatttcttc aatacgattt tgaaatatgt caaagaaggt agtttatacc
     5161 cgttatctta ttatgatggt gattggtacg gtgaagataa agttaaatca aggtttggct
     5221 gtatttggca tggagattca aaagaaacag tactggagaa tgaacgcgca tttttagctg
     5281 aacttgaaca ctattagagt tcggaacata aggcgctaca atgttatgtt gccagtagtt
     5341 gactgaatat gcgcttgtaa caagcttttt tcgattctag tcaacaataa ttaaatttat
     5401 gatatggcaa tactttgtaa tactaatatt aaatggcgac ttttatttca ctatgttata
     5461 agagttgcca ttttgttgat aaaggtatac taaaggttat cgttttgaaa tttttagtaa
     5521 ctagatatgt ttcgtgttat agaccgaatt tgtgtatacg taaaatttaa tgctattgaa
     5581 tttttaaaat gaaaaacatg acattaaatt gaattcataa tatgtctaat tgactaactt
     5641 gttggagtca tttactattt tatgtatgac atattttaaa aagtgagggt caagcatgtc
     5701 ttataaagca tatccattct ttagagatat attaataaat gaatgtattt atttcgcctc
     5761 taaaaataaa aaactagtac gcctaaatta taaaagtgaa gcgtatgtag gcgtttggac
     5821 agaagaaagt gtggccgtat catttttaac aagtcgtgat attccatttg ataaagttgt
     5881 aaaaatggac gttgatcgtt ttgctactta tgaattagat gaattgtttg atgaacaaga
     5941 ccatattatt atgaatcaaa caatggaaga agaagggcat ctactaaacg ttgtagctgt
     6001 tacacaagaa gtgatgacgg aattagataa aattagaatc aaagaatttg tccaagatgt
     6061 agcgaaatat gatgaagtat acggcttaac taaaaaaggt agtaagcagt ttattctcat
     6121 tagtgaaaat gatagcgacg aaaaaaagcc gcatattatg cctgtatgga gtattaaaaa
     6181 cagagcgtta aaagttcgag atgaagattt tgaagagtgt gatttaatta cgattgaagg
     6241 ttctgttttc ggagaatggc tagatgaact tagagatgat cataaagccg ttgcgataga
     6301 tttaaaaact ggcgtggttg gtacaattgt ttcagcgcaa aaattgtcta atgaacttac
     6361 attttaattg aattgagttg taagtaatta agtgataata aatggaacaa tacgtattca
     6421 aaacacgtag accataaaat aaaaggccat ttatatagcg tttatttaaa acaacgctca
     6481 tataaatggt ctttttctat tttcctaaat ataatgcacc aatagcacct gaaaatgcgc
     6541 cgttttcaac atagtacggt ttgcaaccgc gtaacacagt ataatcttcc acaactttgc
     6601 gtaataaagc gttattatga aatgaagaac cgatataaac gatattttca gttttaaatt
     6661 cacgtgcaac agtaatggcc attgtcgtaa caacttcgcc aacgacacca ataacggctg
     6721 ctaatttatt gctaggtgta aaatcagcat ctaaatgatg tagtacatga ccaaaattag
     6781 ctgctgttaa atcaccggga atgggtggtt cggtatcttt ataaatatgt ctaaccttta
     6841 aatcgatagt gttacgatca ccgtgttgtg ccatgtcagt taactgttta taatcagtga
     6901 tttgacttag taaataaccg agtccttgaa tcatgccacc acctgtaccg ataccgccta
     6961 cacgacgttg tgattggcca tcgaaataat gtagtgacgt accggtacca acatttgcaa
     7021 aaatataatc tgctaagtca tggccttgct cttttaacaa aatacctagt ccttgagatg
     7081 cagcatcaaa ctctacaaaa atttgtgcag gaatgttgat gttttcagca atgacacctg
     7141 cattacctcc agttaagcat aatttttcaa tttgctgttg gtttaaccat tccacaactt
     7201 gatcaatatt tttagttaat tcagttttaa aagtacgttg gttatcttgc tcttgaacga
     7261 ttttaattag tgtaccgcca gcgtcaatgc caactttcat aagattccca cctcattatt
     7321 aatgtctatc cttaaataat agtatagtaa aatgactaaa aaacaagtaa taatagtaat
     7381 tattaacaaa tttgatgcca ttgtatttca acattgtaag cgtatcgcaa ttaatgtatt
     7441 acaaacgtag acgttaagtt atatatatta ttttctagga attttgaagt tgtataggat
     7501 tgttagttag tgacgcaata ttaaaagtag ttcgtacgca gtgtatttgt aagtctctga
     7561 ttaaaatgat aagtaatgag gaatagcaca ttaattttaa aaatt
//
LOCUS       DAPSKH010000090         7493 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPSKH010000090 DAPSKH010000000
VERSION     DAPSKH010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7493
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.090"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            82..214
                     /locus_tag="RPH49_002483"
                     /pseudo
     CDS             82..214
                     /locus_tag="RPH49_002483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499947.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            476..1135
                     /gene="arlR"
                     /locus_tag="RPH49_002484"
     CDS             476..1135
                     /gene="arlR"
                     /locus_tag="RPH49_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor ArlR"
                     /protein_id="HDY5125598.1"
                     /translation="MTQILIVEDEQNLARFLELELTHENYNVDTEYDGQDGSDKALSH
                     YYDLIILDLMLPSINGLEICRKIRQQQSTPIIIITAKSDTYDKVAGLDYGADDYIVKP
                     FDIEELLARIRAILRRQPQKDIIDVNGITIDKNAFKVTVNGAEIELTKTEYDLLYLLA
                     ENKNHVMQREQILNHVWGYNSEVETNVVDVYIRYLRNKLKPYDRDKMIETVRGVGYVI
                     R"
     gene            1132..2487
                     /gene="arlS"
                     /locus_tag="RPH49_002485"
     CDS             1132..2487
                     /gene="arlS"
                     /locus_tag="RPH49_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase ArlS"
                     /protein_id="HDY5125599.1"
                     /translation="MTKRKLRNNWIIVTTMITFVTIFLFCLIIIFFLKDTLHNSELDD
                     AERSSSDINNLFHSKPVKDISALDLNASLGNFQEIIIYDEHNNKLFETSNDNTVRVEP
                     GYEHRYFDRVIKKRYKGIEYLIIKEPITTQDFKGYSLLIHSLENYDNIVKSLYIIALA
                     FGVIATIITATISYVFSTQITKPLVSLSNKMIEIRRDGFQNKLQLNTNYEEIDNLANT
                     FNEMMSQIEESFNQQRQFVEDASHELRTPLQIIQGHLNLIQRWGKKDPAVLEESLNIS
                     IEEMNRIIKLVEELLELTKGDVNDISSEAQTVHINDEIRSRIHSLKQLHPDYQFDTDL
                     TSKNLEIKMKPHQFEQLFLIFIDNAIKYDVKNKKIKVKTRLKNKQKIIEITDHGIGIP
                     EEDQDFIFDRFYRVDKSRSRSQGGNGLGLSIAQKIIQLNGGSIKIKSEINKGTTFKII
                     F"
     gene            3012..5810
                     /locus_tag="RPH49_002486"
     CDS             3012..5810
                     /locus_tag="RPH49_002486"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDY5125600.1"
                     /translation="MTNERKEVSEAPVNFGANLGLMLDLYDDFLQDPSSVPEDLQVLF
                     STIKNDDSIVPALKSTSSQNSDGTIKRVMRLIDNIRQYGHLKADIYPVNPPKRKHVPK
                     LEIEDFDLDQQTLEGISAGIVSDHFADIYDNAYEAILRMEKRYKGPIAFEYTHINNNT
                     ERGWLKRRIETPYKVTLNNNEKRALFKQLAYVEGFEKYLHKNFVGAKRFSIEGVDALV
                     PMLQRTITIAAKEGIKNIQIGMAHRGRLNVLTHVLEKPYEMMISEFMHTDPMKFLPED
                     GSLQLTAGWTGDVKYHLGGIKTTDSYGTMQRIALANNPSHLEIVAPVVEGRTRAAQDD
                     TQRAGAPTTDHHKAMPIIIHGDAAYPGQGINFETMNLGNLKGYSTGGSLHIITNNRIG
                     FTTEPIDARSTTYSTDVAKGYDVPIFHVNADDVEATIEAIDIAMEFRKEFHKDVVIDL
                     VGYRRFGHNEMDEPSITNPVPYQNIRKHDSVEYVFGKKLVNEGVISEDEMHSFIEQVQ
                     KELRQAHDKINKADKMDNPDMEKPAELALPLQADEQSFTFDHLKEINDALLTYPDGFN
                     ILKKLNKVLEKRHEPFNKEDGLVDWAQAEQLAFATILQDGTPIRLTGQDSERGTFSHR
                     HAVLHDEQTGETYTPLHHVPDQKATFDIHNSPLSEAAVVGFEYGYNVENKKSFNIWEA
                     QYGDFANMSQMIFDNFLFSSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLAA
                     ENNCTVVNLSSSSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSG
                     GFEPILTESYQADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIE
                     ALLAQLPNLEEVSWVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDG
                     EIHKLVQNKIIENALKNN"
     gene            5824..7092
                     /gene="sucB"
                     /locus_tag="RPH49_002487"
     CDS             5824..7092
                     /gene="sucB"
                     /locus_tag="RPH49_002487"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDY5125601.1"
                     /translation="MPEVKVPELAESITEGTIAEWLKNVGDSVEKGEAILELETDKVN
                     VEVVSEEAGVLSEQLASEGDTVEVGQAIAIIGEGSGNASKENSNDNTPQQNEETNNKK
                     EETTNNSVDKAEVNQANDDNQQRINATPSARRYARENGVNLAEVSPKTNDVVRKEDID
                     KKQQAPASTQTTQQAPAKEEKKYNQYPTKPVIREKMSRRKKTAAKKLLEVSNNTAMLT
                     TFNEVDMTNVMELRKRKKEQFMKDHDGTKLGFMSFFTKASVAALKKYPEVNAEIDGDD
                     MITKQYYDIGVAVSTDDGLLVPFVRDCDKKNFAEIEAEIANLAVKAREKKLGLDDMVN
                     GSFTITNGGIFGSMMSTPIINGNQAAILGMHSIITRPIAIDQDTIENRPMMYIALSYD
                     HRIIDGKEAVGFLKTIKELIENPEDLLLES"
BASE COUNT         2817 a         1094 c         1359 g         2223 t
ORIGIN      
        1 attagaatta gaatatttaa aagtgatgag gtttaaaaat tatattgttt acatactcct
       61 tttgaattca tacattaaga aatgttactt gtaagttcaa aatcgcacat tgaaatgatg
      121 tgtgaaaatg tttaaactac ggtcattttg tgaaaataaa gataataact attcatttta
      181 caatagtgaa aagtcagtat atgacaacaa ttaatattgc ggtaaggcct tgtgttacag
      241 tattctatat ttaagtactg caatcagaat taacagaatt ccattaactg atcattaaat
      301 atttgagtta ataaataatt aatgattgta gcttgaaaaa tttaaaacat ggttattgat
      361 ttgtgataaa atttaaacgt aaacaaacta atttaaaaag caactattgt atagaaaaat
      421 acaaaattta aaatatatta ccttattaga aaaagtcgta atatgaggtg tacaaatgac
      481 gcaaatttta atagtagaag atgaacaaaa cttagcaaga tttcttgaat tggaactcac
      541 acatgaaaat tacaatgtgg acactgagta tgatggacaa gacggttcag ataaagcgct
      601 tagccattac tatgatttaa tcatattaga tttaatgttg ccttcaatta atggcttaga
      661 aatttgtcgc aaaattagac aacaacaatc tacacctatc attataatta cagcgaaaag
      721 tgacacgtat gacaaagttg ctgggcttga ttacggtgca gacgattata tagttaagcc
      781 atttgatatt gaagaacttt tagcaagaat tcgtgcgatt ttacgtcgtc agccacaaaa
      841 ggatattatc gatgttaacg gtattacaat tgataagaat gcttttaaag tgacggtaaa
      901 tggcgcagaa attgaattaa caaaaacaga gtatgattta ctatatcttc tagctgaaaa
      961 taaaaaccat gttatgcaac gggaacaaat tttaaatcat gtatggggtt ataatagtga
     1021 agtagaaaca aatgtcgtag atgtttatat aagatattta cgaaacaaat taaaaccata
     1081 cgatcgtgac aaaatgattg aaacagttcg tggcgttggg tatgtgatac gatgacaaaa
     1141 cgtaaattgc gcaataactg gattattgtt accacgatga ttacgtttgt cacgatattt
     1201 ttgttttgtt taattattat ctttttcttg aaagatacac tgcataatag tgagcttgat
     1261 gatgcagaac gaagctcaag cgatattaat aatttatttc attctaagcc tgttaaagat
     1321 atatctgcat tagacttgaa tgcatcttta ggtaattttc aagagattat tatttatgat
     1381 gaacataata ataaattatt tgagacatcg aatgataaca cagtgagagt tgaaccaggt
     1441 tatgaacacc gttattttga ccgcgtaata aaaaaacgct ataaaggcat tgaatattta
     1501 attattaaag aaccaatcac aacgcaagat ttcaaagggt atagcttgtt aattcattca
     1561 ctagaaaatt atgataacat cgtaaaatca ttgtatatca ttgcgctcgc atttggagtg
     1621 attgcaacaa ttataactgc cacaatcagt tatgtatttt caactcaaat tactaaaccg
     1681 cttgtcagtt tatcaaataa aatgattgag attcgacgag atggatttca aaataaattg
     1741 caattaaata caaattatga agaaatagat aatctagcaa atacgtttaa tgagatgatg
     1801 agccaaattg aagaatcatt taatcaacaa agacaatttg ttgaagatgc atcacatgaa
     1861 ttacgaacac cattacaaat tattcaaggt catttaaatt tgattcagcg atggggaaaa
     1921 aaagatccag cagtattaga agaatcgtta aatatttcta ttgaagaaat gaatcgtatc
     1981 ataaaattag tcgaagaatt acttgaattg actaaaggag atgtaaatga catttcttct
     2041 gaagcgcaga ccgtgcatat taatgatgaa attcgctcgc gaatacactc attaaaacaa
     2101 ttacatcctg attatcaatt tgatacggat ctgacatcta aaaatttaga aattaaaatg
     2161 aagcctcatc aatttgaaca attattttta atctttattg ataatgcaat caaatatgat
     2221 gtgaagaata agaaaattaa agttaagaca aggttaaaaa ataagcaaaa aataattgaa
     2281 attacagatc atggaattgg tattccagag gaagatcaag atttcatttt tgatcgcttt
     2341 tatcgagtgg ataaatctcg ttcaagaagt caaggcggta atggactcgg attatctatt
     2401 gctcaaaaaa tcattcaatt aaacggtgga tcgattaaaa ttaaaagtga aattaacaaa
     2461 ggaacaacgt ttaaaatcat attttaatta tgtttgagcc gtcaatcaaa atcataggat
     2521 caatttttta agtgaggctg ggacataaat caatgttcta tgctttacga agttatattg
     2581 gcagtagttg actgaacgaa aatgcgcttg taacaagctt ttttcaattc tagtcagggg
     2641 cccaacacag aagctgacga aaagtcagct tacaataatg tgcaagttgg ggatgggccc
     2701 caacacagag aatttcgaaa agaaattcta caggcaatgc aagttggggt gggacgacga
     2761 aataaatttt gcgaaaatat catttctgtc ccactcccaa gaacgactat aaaacaaata
     2821 aacagtggtt ctttatcatt tctgttgtac gcccaaaatt tacaataaaa tacatctata
     2881 aacctagaag aatcaacgct tttgttgatt cttcttttta gcagataaat aggtaaatct
     2941 actttaacaa ataactaaat agtgatatta ttacattgta agcgtttcaa catttttgtg
     3001 gagggtgtaa aatgactaac gaaagaaaag aagtttcaga ggctcctgta aacttcggtg
     3061 cgaatttagg tctaatgtta gatctatatg atgacttttt acaagatcca tcatctgtac
     3121 cagaagattt acaagtctta ttcagcacaa ttaagaatga tgactcaatt gtaccagctt
     3181 taaaaagtac aagtagtcaa aatagcgacg gcacaattaa acgtgtcatg cgtttaattg
     3241 ataatattcg ccaatacggg catcttaaag ccgatattta tcctgtaaat cctccgaaaa
     3301 ggaaacatgt acctaaatta gagattgaag actttgattt agatcaacag actttggaag
     3361 gtatatcagc aggaattgtt tcagatcact ttgccgacat ttatgataat gcttatgaag
     3421 caattttaag aatggaaaaa cgttacaaag gaccaattgc atttgagtat acacatatta
     3481 ataacaatac cgaacgtggt tggttaaaaa gaagaattga aacgccatat aaagtaacgt
     3541 taaataacaa cgaaaaaagg gcactattta aacaattagc gtatgttgaa gggttcgaaa
     3601 aatatcttca taaaaacttc gttggtgcaa agcgtttttc aattgaaggg gtagacgcac
     3661 tcgtaccgat gttacaacgt actattacga ttgctgcgaa agaaggtatt aaaaatatac
     3721 aaataggcat ggctcaccgt ggacgtttaa acgttttaac gcatgtctta gaaaaaccgt
     3781 acgaaatgat gatttcagaa tttatgcata cagatccaat gaaattctta cctgaagatg
     3841 gtagcttgca gttaactgct ggatggactg gtgatgtgaa atatcacctt ggtggcatta
     3901 aaactactga ttcatacggt acaatgcagc gtattgcact ggctaacaat ccaagtcact
     3961 tggaaattgt tgcacctgtt gttgaggggc gtacgagagc agcacaagat gatacacaac
     4021 gtgctggggc tccgacgact gatcatcata aagcaatgcc aattattata catggcgatg
     4081 ctgcttatcc tggtcaagga attaacttcg aaacaatgaa cttaggaaac ttgaaaggct
     4141 attctacggg tggttcattg catattatta ctaacaatag aattggattt actacagaac
     4201 caattgatgc acgttcaaca acttattcta cagatgtggc caaaggttat gatgtgccaa
     4261 tattccatgt caatgctgat gacgttgaag ctactattga agcaattgat attgcaatgg
     4321 aatttagaaa agagtttcat aaagacgtcg ttattgattt agtaggttat cgtcgtttcg
     4381 gtcataacga aatggatgaa ccatcaatta ctaatccagt tccttatcag aatattcgca
     4441 aacatgactc tgttgaatat gtgtttggta aaaagcttgt taatgaaggt gtcatttcag
     4501 aagatgaaat gcattcattt atagaacaag tccaaaagga actaagacaa gcacatgata
     4561 aaattaataa agctgataaa atggataatc cagatatgga aaaacctgca gaacttgcat
     4621 taccgttaca agcagacgaa caatcattta cgtttgatca tttgaaagaa ataaatgatg
     4681 cattgttaac atatccggat ggctttaaca ttttgaaaaa gttaaacaaa gttcttgaga
     4741 agcgtcatga gccgtttaat aaagaggatg gcttagttga ttgggcacaa gcagaacaac
     4801 ttgcatttgc gacaatttta caagatggta caccgattcg cttaactggt caagatagtg
     4861 aacgtggtac attcagtcat aggcatgccg tgttacatga tgagcaaaca ggtgaaacat
     4921 atacaccttt acatcatgtt cctgatcaaa aagcgacatt tgatatacac aattctccgc
     4981 tttcagaagc agcagtagtt ggttttgaat acggctataa tgtggaaaac aaaaaaagct
     5041 tcaatatttg ggaagcgcaa tatggtgatt ttgcaaatat gtcacaaatg atttttgaca
     5101 acttcttatt cagttctcgc tcaaaatggg gagaacgttc aggattaaca ttattcttac
     5161 ctcatgcata tgagggtcaa ggtcctgaac attcatcagc aagattagag cgatttttac
     5221 aattagctgc tgaaaataat tgcacagttg tcaacttatc tagttcaagt aattatttcc
     5281 acttattgcg tgcacaagca gctagtttag attctgaaca aatgcgacca ttggttgtta
     5341 tgtcaccaaa aagcttactg agaaataaaa cagttgcaaa accaattgat gaatttactt
     5401 ctggtggatt tgagccaatt ttgacagaat catatcaagc ggataaggtt acaaaagtta
     5461 ttttagcaac tggtaaaatg ttcattgatt taaaagaagc attagctaaa aatccagacg
     5521 aatcagtgtt actcgttgcg attgaaagat tgtatccatt cccagaggaa gagattgaag
     5581 cattactagc acaattgcca aaccttgaag aagtgtcatg ggtacaagaa gaacctaaaa
     5641 atcaaggtgc atggttatat gtctatccat atgttaaagt gctagttgca gataaatatg
     5701 atttaagtta tcatggcaga attcaaaggg ctgctccagc tgaaggcgat ggagaaattc
     5761 ataaacttgt tcaaaataaa attatagaaa atgcattaaa aaataactag ggggaaataa
     5821 gtcatgccag aggttaaagt tccagaatta gcagaatcta ttacagaagg taccattgca
     5881 gaatggttga aaaacgtagg ggatagcgta gaaaaaggtg aagctattct tgaattagaa
     5941 actgataaag ttaatgtcga agttgtatct gaagaagcag gtgtattatc tgaacaactt
     6001 gcaagtgaag gcgacactgt agaagttggg caagcaattg ctatcatcgg cgaaggtagt
     6061 ggcaatgctt ctaaagaaaa tagtaacgac aatactccac aacaaaatga agaaacaaat
     6121 aataaaaaag aagaaacaac aaataattcg gtagataaag ctgaagtcaa tcaagcaaat
     6181 gatgacaatc agcaacgtat taatgctacg ccttctgcgc gtcgatatgc tcgtgaaaat
     6241 ggtgtcaatc ttgctgaagt aagtccaaaa acaaatgatg tggttcgtaa agaagatatt
     6301 gataagaaac aacaggcacc ggcatcaaca caaacaacac aacaagcacc tgcaaaagaa
     6361 gagaaaaaat acaatcaata tcctacaaaa ccagtgattc gtgaaaaaat gtcacgcaga
     6421 aagaaaacag ctgccaaaaa attattagag gtatctaata atacagctat gttaacaaca
     6481 tttaacgaag ttgacatgac aaatgttatg gaattgcgta aacgtaagaa agaacaattt
     6541 atgaaagatc atgatggtac taaattagga tttatgtcat tctttactaa agcttcagta
     6601 gcagctttga aaaagtatcc agaagttaat gcagaaatcg acggcgacga catgattacg
     6661 aaacaatatt atgatattgg tgtagctgtt tctacagatg atggattatt agtaccattt
     6721 gtaagagatt gtgataaaaa gaattttgca gaaatcgaag cagaaattgc taatttagct
     6781 gttaaagcac gagagaaaaa acttggctta gatgatatgg ttaatggttc atttacgatt
     6841 acaaatggcg gtatttttgg atcaatgatg agtacgccaa ttatcaatgg taatcaagct
     6901 gcaatcttag gcatgcattc aattattaca agaccaattg cgattgatca agatacaatc
     6961 gaaaatcgtc caatgatgta tattgcatta agctatgatc atagaattat tgacggtaaa
     7021 gaagcagttg gattcttaaa aacaattaaa gaattaattg aaaacccaga agacttatta
     7081 ttagaatctt aatccacaac acaaaatagt ttactattcc taaaaacgta atcaaatcaa
     7141 taacaaacag cagtaagatt attttctagt cgaaatatct tactgctgta ctttattttt
     7201 ataatgcttc gtattaaaat gtgagtttaa ttttgacaac ttaaaaaata tatcattttt
     7261 attgaaatag actcacaata gaaatatagg tggaatggcg tgtttcaata tgctaatgaa
     7321 atcattttag ataataacaa gcgatgaaat ttatgaattc tataagcgcc tttagttaat
     7381 ttaaaatcat ctgaacaaga tgtaaattca ctttatggat acgacatgta tatgtttttt
     7441 atgtactaca taaaacgaaa tattcaattg ctatatacag atactcatta atg
//
LOCUS       DAPSKH010000091         7402 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPSKH010000091 DAPSKH010000000
VERSION     DAPSKH010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7402
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.091"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(112..804)
                     /locus_tag="RPH49_002488"
     CDS             complement(112..804)
                     /locus_tag="RPH49_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDY5125602.1"
                     /translation="MNYSPKQGVRSHGLPHDPFKSSTVPRPIGWISTVSKDGKDNLAP
                     YSQYQNLTWDPPMVMFAANQSVLGDHERKDTVKNAEETGWFVWNMATYDLREAVNLSS
                     KALPPEEDEFEYAGVTKEACIEAPGYRVKESPVHFECEYVQTIRIPTGDLVSTVDIVI
                     GRVAQVHIDDKVILDNGKLDIKSIKPIARLGYYDYTVVNEIFEMKAPSASKEELAGLE
                     GRNFDNQSDDKE"
     gene            1136..1771
                     /locus_tag="RPH49_002489"
                     /pseudo
     CDS             1136..1771
                     /locus_tag="RPH49_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226788.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1758..2060
                     /locus_tag="RPH49_002490"
     CDS             1758..2060
                     /locus_tag="RPH49_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125603.1"
                     /translation="MRTNNHITDLDAIELSSAWNYNSKLVTGKNALLSDSLLRDIKVL
                     SSNAKGDADMLETELHAVINAMSQNEGKSVDALKNSTASLKNNLTKLKEQLDKTTH"
     gene            2211..2570
                     /locus_tag="RPH49_002491"
     CDS             2211..2570
                     /locus_tag="RPH49_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125604.1"
                     /translation="MILRYVTNLKLAKELYQASKPKLQEDKGMIELFEHTFGLQKELV
                     KYVGIAEATTAALYSASFINKNISRIASLSTIGILSVATYKHFEAGQGKKGAQHALDL
                     LGLATLSLLDTFSCNKK"
     gene            complement(2655..3266)
                     /locus_tag="RPH49_002492"
     CDS             complement(2655..3266)
                     /locus_tag="RPH49_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDY5125605.1"
                     /translation="MYTFDAQSLTARENYKLLIGSIIPRPIAFVTTLNQDASVNAAPF
                     SFFNIVNNHPPMIAIAVQRAGGKRKDTALNIERTGDFVVHITDEDNVQDINETAAPLA
                     YGDSELSRTKLSLLTSTTIKTPGIKDAKMRFECKLSQMILLGDVLDGADLIIGEIVTY
                     HIDDSIYEGDFKINPHALQAVSRLAGNDYAKLGGLFTIDRPEK"
     gene            complement(3345..3821)
                     /locus_tag="RPH49_002493"
     CDS             complement(3345..3821)
                     /locus_tag="RPH49_002493"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase"
                     /protein_id="HDY5125606.1"
                     /translation="MAVVYVAGGCLWGVETFFATIPGIIHTEAGRANGRSSKLDGPYD
                     GYAECVKLHFDDRMLTITDIMNYLFEIIDPYSVNQQGNDIGEKYRTGLYSCVDDHLIE
                     ARQFIERRKDRDQIAVEVLPLSNYIKSAEEHQQHLEKYPEDMHMCHISKDLLNKYK"
     gene            complement(3824..4324)
                     /locus_tag="RPH49_002494"
     CDS             complement(3824..4324)
                     /locus_tag="RPH49_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125607.1"
                     /translation="MVLRKVTMQDLDQIIALENIGFSPEEAATPEALKLRIEQIQETF
                     IVAEKNDEVIGYINGPVIKERYISDDLFKNVSTNNSEGGYISVLGLVVAPNYQGQGIA
                     GRLLNYFENLAKNQHRHGVTLTCRESLISFYEKYGYRNEGVSESCHGGIKWYNLVKNI
                     KKDDEV"
     gene            complement(4559..5326)
                     /locus_tag="RPH49_002495"
     CDS             complement(4559..5326)
                     /locus_tag="RPH49_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase"
                     /protein_id="HDY5125608.1"
                     /translation="MIDIHNHILVDIDDGPKTIEKSIALLKQAKDEGVTSIVATPHHL
                     HPRYDNTFQQVLVKLAELRTHPEVQALDIKLFPGQEIRITDSILQGLDNGSIQGINRS
                     KYLLIEFPTGEVPHYTKQLFFEIQSRGYIPIIAHPERNRSIAKNPEILYELVANGALS
                     QLTSSSLVGGFGKNIQKLSLQFIECNLAHFVASDAHSCDQRPFLMQELFHNHKLKKYS
                     NDIEALLRNASSVINDNFVYLDRPTKPGKVKSFLKWF"
     gene            complement(5323..6015)
                     /locus_tag="RPH49_002496"
     CDS             complement(5323..6015)
                     /locus_tag="RPH49_002496"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HDY5125609.1"
                     /translation="MTNTRRSTSSLIVHEQPKSPISEKFRGIRSNIMFANPDSAVQSI
                     VITSEAPGAGKSTIAANLAVAYAQAGYKTLIVDGDMRKPTQHYIFNLPNNEGLSSLLL
                     NWSTYQDSIISTEIEDLDVLTSGPIPPNPSELITSRAFANLYDTLLMNYNFVIIDTPP
                     VNTVTDAQLFSKFTGNVVYVVNSENNNKDEVKKGKELIEATGAKLLGVVLNRMPKDKS
                     ASYYAYYGTDES"
     gene            complement(6032..6694)
                     /locus_tag="RPH49_002497"
     CDS             complement(6032..6694)
                     /locus_tag="RPH49_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CapA"
                     /protein_id="HDY5125610.1"
                     /translation="MKEKFDLVKLLNILKKNIKLLLILPAICLVVSAALTFFVMPDKY
                     TASTQILVNMKKSSSDLAFQNVQSSLQSVNTYTEIIKSPRILDKVSREFDGQYSTAEL
                     NSFLKVTNQTNSQIITVSVTTGNKSESDKIVNKISKVFAHDMPKIMSVDNVTILSSAH
                     DNAVKVSPIVSVNLVISIIVGIVLAILIIFLKELLDKRIKTEEDVESQLGLPILGSIQ
                     KF"
BASE COUNT         2446 a         1327 c         1037 g         2592 t
ORIGIN      
        1 tctttaaaat tataaatata gcgacatatc gcttcccggt tttgaaatat aaaaatacat
       61 cgaaactaat ttcaacgtgt agtttcgatg tattgaaaat gattgaattc attattcctt
      121 gtcatctgat tgattatcaa aatttcttcc ttctaaacct gcaagctctt ctttagaagc
      181 tgatggtgct ttcatttcaa atatttcatt cacaaccgtg taatcataat atcctaacct
      241 cgcaataggt ttaatcgact taatgtctaa tttaccatta tcaagaatga ccttatcgtc
      301 aatatgaacc tgagcaactc ttcctataac aatatcaact gttgatacaa ggtctcctgt
      361 cggaatacga atcgtttgaa cgtactcaca ttcaaaatgt actggcgatt ctttgactcg
      421 ataacctggt gcttctatac atgcttcttt cgtcacacct gcatattcaa attcatcctc
      481 ttcaggtggt agtgccttcg acgataaatt aactgcttct cttaaatcat acgttgccat
      541 attccacaca aaccaccctg tctcttcagc atttttcact gtatctttac gttcgtgatc
      601 accaagaacg gattgatttg ctgcgaacat aaccataggc ggatcccaag ttaagttttg
      661 atactgacta taaggtgcta aattatcttt cccatctttc gatacagtag agatccaccc
      721 tattggacgt ggtactgtac tacttttaaa tggatcgtgt ggtaagccat gactccttac
      781 accttgcttc ggcgaataat tcattctatc ctcacccctt attagtaatt acatttaagg
      841 ttacgccctc tttacataag cgtctaatat aaataatcaa tttatttata agtagaaact
      901 atatatgacg tggtttctta taatttgcgt tcttgattcg aaaatttcag ataaagattt
      961 atgcaattaa tatttatgat atctttttgt aaatttaatt aattatagtt acttcaatca
     1021 tgattagttt ataataatat tgaataacaa tattttagtt tttgtataat ttgcctatca
     1081 actgaaaaaa cagctaatac aaaggagcta atgaagatat gagaaaaatt atgcgaacct
     1141 tattatgcac atcaatcata ttcaactcca attacttttt gttgagtctg gaaatggcat
     1201 aactatttca acatttacac ctggtcatat aaatgaaaca tcagcggcag ttgcagccat
     1261 gatgtacaaa cgttatgaac atgaaattga acaagctcga ttaaaattca aatcagaagt
     1321 tgagaaaaat ggttattatg ccatgaataa aaaacttcaa aagaagcaag aattcaatgg
     1381 tgttactaaa caatttttga atttcaacac agacagtatc gatgacttaa aaaagtttaa
     1441 acaagaattc aaacctgtta tgcacttaaa aggagaagcg tttaatcaac aattacaatc
     1501 tttgattaat aaatatcctc aaatacaaaa aaatatgaaa tcagagttca ttgcttatta
     1561 tgataaagaa aaaaatagag aaacagtaaa aaactatgct tggaaccttc aaaaatctat
     1621 aaatgacgtt atgcaatcat atcctagcac aaaatttgta cagttttata aagatgatat
     1681 ttccccgtca atggtagatg gaaatggccg tttaaaatcg gatactaatg taatttccaa
     1741 cgagggagga aagtatgatg agaacaaata atcatataac cgatttagat gctattgaat
     1801 taagcagtgc ttggaattac aattcgaaat tggtgactgg caaaaatgca ctactatcag
     1861 atagcctttt aagagatatt aaagtattaa gttctaatgc taaaggtgac gcagacatgt
     1921 tagaaactga acttcatgct gttataaacg caatgtctca aaacgaaggt aaatctgttg
     1981 atgcacttaa aaatagtacc gcttctctaa aaaacaatct aaccaaatta aaagagcaac
     2041 tcgataaaac cacacattaa attcatatat tttgagtgaa tagaattata tttccatagc
     2101 aaatattcct gaactacaca tgttacataa gagattcatt tttgaagaaa cgggtaaaat
     2161 gataaagtaa ttatctttca caaaaatcca aatattggga ggaattaaat atgattttac
     2221 gttacgtgac caatttaaaa cttgcgaaag agctatacca agccagtaaa cctaaattgc
     2281 aagaagataa gggtatgatt gaactgtttg agcatacttt tggcttgcaa aaagaacttg
     2341 taaaatacgt cggcattgca gaagcaacta ctgctgcttt atactcagct agctttatca
     2401 ataaaaacat ttctcgcatt gcttcgctat caacaatagg tattttaagt gtagctactt
     2461 acaaacattt cgaagctggc caaggtaaaa aaggtgcaca acatgcatta gatttattag
     2521 gtcttgctac tttaagttta ctagatacat tttcttgtaa taaaaaatag tcttcatttt
     2581 agaagcacat actttagcac ctgtgtactt ttgattcaat tcataaacgg tacaccgcta
     2641 tagcatgtgt tttgttattt ttcaggtcta tctattgtaa ataatcctcc taatttagca
     2701 taatcatttc cggctaaacg agaaacagcc tgtaatgcgt gtggattgat tttaaaatca
     2761 ccctcataaa tactgtcatc aatatgataa gttacaattt cgcctattat taagtcagcc
     2821 ccatctaata catctccaag caatatcatt tgcgatagtt tacattcgaa tctcattttc
     2881 gcgtctttaa ttcctggcgt cttaatcgtt gtagatgtta aaagtgataa ttttgtacga
     2941 ctcaactcac tgtctccata tgctaacggc gctgcagtct cattaatatc ttgaacatta
     3001 tcttcgtctg taatatgcac aacaaagtct ccagtccgtt ctatattcaa tgcagtatct
     3061 tttctcttac ctcctgcacg ttgaactgca atagcaatca ttggcggatg gttattaaca
     3121 atattaaaaa agctaaatgg tgctgcattt actgatgcat cttgatttaa tgttgtaaca
     3181 aatgctatag gtcgtggaat aattgaacca attaataatt tatagttttc tctagcagtt
     3241 aatgattgtg catcaaacgt atacataata cctacctctt ttctaagtat atctaggtat
     3301 ttctccgatt ttggttaatt taaacatcta ttctcctctg aaaatcactt gtatttattt
     3361 agcaaatctt ttgaaatatg acacatatgc atatcttctg gatatttttc taaatgttgc
     3421 tgatgttctt cagcactttt aatgtagtta gacagcggta agacttccac tgcaatttga
     3481 tctctgtctt tacgtcgttc aatgaactga cgcgcttcaa ttaagtggtc atctacacaa
     3541 ctatataaac ccgttcgata cttttctcca atatcatttc cttgttgatt cacactgtaa
     3601 ggatcaatga tttcaaataa ataattcata atgtctgtaa ttgttaacat acgatcatcg
     3661 aaatgaagtt tgacacattc agcataacca tcatacggac cgtctaattt agagcttctt
     3721 ccatttgctc ttcctgcttc tgtatgtata attccaggta ttgttgcaaa aaatgtttca
     3781 acaccccata aacatcctcc tgctacataa acaactgcca tatttacacc tcatcatcct
     3841 tttttatatt tttaacaagg ttataccatt taataccgcc atgacatgat tctgatacac
     3901 cttcattacg atacccatat ttttcataaa aagaaattaa tgattctcga catgttaacg
     3961 ttacaccatg tcgatgttga ttcttagcaa gattttcaaa atagtttagt aagcgacctg
     4021 caataccctg accttgataa tttggtgcta caacaagacc taacacacta atatagccac
     4081 cttcactatt atttgtggag acatttttaa ataaatcatc gctaatgtaa cgctctttta
     4141 tgactggacc attgatgtat ccaattactt catcattctt ttcagctaca ataaaagttt
     4201 cttgaatttg ttcaattctc aatttcaatg cctctggtgt tgcagcttct tccggtgaaa
     4261 aaccaatatt ttcaagtgca ataatttgat ctaagtcctg catggttact tttcttaata
     4321 ccataaaaac acttccttag ccctatatat caaaagtaat accttcatct ttatattcat
     4381 tattttcaag ctaccttcac tataaaaaac gagtcttttt attaaaagcc attcgcctta
     4441 atcaattaga caagttgttt tatacgaatt agcaaataat catgattata attcatttta
     4501 agcatactca aaaagactgg tacatgtata ccagtctaat tcgaaaaaat atatttagtt
     4561 aaaaccattt caaaaacgac ttcacttttc ctggcttagt cggtctgtct aaataaacaa
     4621 aattatcatt gattactgaa ctggcatttc gaagtaatgc ttcaatgtca ttcgaatatt
     4681 tcttcaattt atgattgtga aataattctt gcatcaaaaa tggtctttgg tcacatgaat
     4741 gtgcatctga agctacaaaa tgagccaaat tacattctat aaattgtaat gataactttt
     4801 gaatgttttt tccaaatcca ccaactaaag aactcgatgt taattgactc aatgccccat
     4861 ttgcaacaag ttcatataat atttctggat ttttggcgat acttctattt ctttcaggat
     4921 gtgcaatgat tggtatgtaa cctctcgatt gtatttcaaa aaacaattgt tttgtataat
     4981 gtggtacttc gcccgttgga aattcaatta ataaatattt cgaacgatta ataccttgaa
     5041 tactaccatt atctaagcct tgcagaatcg aatctgtaat tctaatttct tgcccgggaa
     5101 ataatttaat atccaatgct tgaacttctg gatgcgttct taactccgcc aatttcacaa
     5161 gcacttgttg aaatgtatta tcatatctcg gatgcaaatg atgaggtgtc gctacaatac
     5221 ttgttacacc ttcatcctta gcttgcttta atagtgcaat actcttttca attgttttag
     5281 gaccatcatc tatatcaact aatatatggt tatgaatatc aatcatgatt catcagtccc
     5341 ataatatgca tagtaactag cacttttatc tttaggcatt ctatttaaga ctacacctaa
     5401 taatttagca cctgttgctt caataagttc ttttcctttt ttaacttcat ctttattatt
     5461 attttccgaa ttaactacgt agacaacatt gccggtaaac tttgaaaata attgcgcatc
     5521 tgtaactgtg ttcactggcg gcgtatcgat aataacaaag ttataattca tcaataatgt
     5581 gtcatacaaa tttgcaaatg ctcttgatgt gattaactct gatgggtttg gcggaatcgg
     5641 tccagacgtc aggacgtcta aatcttcaat ttcagttgag ataatactgt cttgataagt
     5701 tgaccaattt agcaataaac ttgataggcc ttcattgttt ggtaaattaa aaatatagtg
     5761 ctgcgtaggt ttacgcatat ccccatctac gattaatgtt ttataacctg cttgtgcata
     5821 tgcaactgct aaatttgctg caattgtaga cttacctgcg cctggtgcct ctgaagtgat
     5881 tacaatgctt tgaactgcac tgtcaggatt tgcaaacata atatttgatc ttatgcctcg
     5941 aaatttctcg ctaataggtg actttggttg ttcatggaca attaaacttg atgtacttct
     6001 tcgtgtattc gtcatggtaa ttcctcgtaa attaaaattt ttgtattgaa cctaaaatag
     6061 gtaatcctag ttgcgattca acatcttctt ccgtcttaat acgcttatct aatagttctt
     6121 ttaagaaaat aatcaatatt gctaaaacaa taccaacaat gatgctgatc actaagttga
     6181 cagagactat cggagatact tttacagcat tatcatgcgc tgaggaaagt atcgtaacat
     6241 tatcaacact cataatttta ggcatgtcat gagcaaaaac tttagatatt ttattaacaa
     6301 ttttgtcaga ttcagattta ttcccagttg taactgatac agtaataatt tgagagtttg
     6361 tttgattggt tacttttaaa aacgaattca actcagctgt tgaatactgg ccatcaaact
     6421 ctctagatac tttatctaga attcttggac ttttgataat ttccgtatat gtattaacag
     6481 actgcaaact actttgaaca ttttggaaag ctaaatcact tgaggacttt ttcatgttca
     6541 ctaatatttg agtagaagca gtatatttgt caggcataac aaaaaaggtt aatgccgcac
     6601 ttactacaag acatattgcc ggtaaaataa gcaataattt aatattcttc tttagaatat
     6661 ttaatagttt tactaaatca aacttttctt tcatggtttc ctccacataa tcaatcattg
     6721 tattcattat gtatgtttta taaatcggac aattgtatct agtttaacga ccacaaaaca
     6781 tacacaacta cattttctct aattatttat ataaatattt tatcgtttaa aattatatca
     6841 tgattcttgg gcattatgta taacttattt atatttttgc tcaagatata atattgtcca
     6901 actttaaata tccaaaccta ttaataataa atctagatac catcgtactc tatcatggct
     6961 ttcttataat cgagtagaag catcatcatt acttaattat ttgctcttta caacaccgag
     7021 cgtgcccgta ctcggtagtt caataccttg cgtaatccgt cactgtgaat tgggttaatg
     7081 ataataaagc ccacaccttt taaaaagatg tgggtaattt atataatttt tatttacatt
     7141 ttaaacttat aaaaaatgag cgcctatgtc atgatttacc atcacatagg cgcttatcaa
     7201 taaattatta attattactt tccatttcat ctaatttata cggatttcct gtaattagat
     7261 gacaacttat tcttttcagg ggaacattac acttttataa tattttcaaa gacaaactta
     7321 accattcaca aatataaaga atattattat caaatcattg aacaaatcgt attttgcaac
     7381 aattgatatt tatattaatg ta
//
LOCUS       DAPSKH010000092         6951 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPSKH010000092 DAPSKH010000000
VERSION     DAPSKH010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6951)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6951)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6951
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.093"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            71..499
                     /locus_tag="RPH49_002498"
     CDS             71..499
                     /locus_tag="RPH49_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125611.1"
                     /translation="MTRSALKPFKNKRVMVTGRIQRVLFKNYLDRHSTFKPNVRILLK
                     DVFVSGVSIDHLWLYETNKYYALAMELIHQRVKFSANVVPYYKINRNNNLFVQDYGIK
                     RKGRLITEEAYNQNNQYQDKIYEKLPDIDFRLEDFYSKEN"
     gene            complement(708..1214)
                     /locus_tag="RPH49_002499"
     CDS             complement(708..1214)
                     /locus_tag="RPH49_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125612.1"
                     /translation="MAHIIRRVSIKDVENFISMLAKIYDESPYMFYTPGEYDPSVTSA
                     SKQLEEYITSPHKVIFVAESDEQLVGFAFVNTTPFQRIKHVAKIDLGVKKLYQHRGIG
                     QALLDAIMAWCLNNQIHRIEANVPLNNQPALELFKSADFQIEGVLKDKLFIDGKYYDD
                     YMMAKILN"
     gene            1327..2250
                     /gene="graX"
                     /locus_tag="RPH49_002500"
                     /gene_synonym="apsX"
     CDS             1327..2250
                     /gene="graX"
                     /locus_tag="RPH49_002500"
                     /gene_synonym="apsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="auxiliary protein GraX/ApsX"
                     /protein_id="HDY5125613.1"
                     /translation="MKPKVLLAGGTGYIGKYLSEVIENDAELFAISKYPDNKKTDDVE
                     MTWIQCDIFHYEQVVAAMNQVDIAVFFIDPTKNSAKITQSSARDLTLIAADNFGRAAA
                     INQVKKVIYIPGSRYDNETIERLGAYGTTVETTNLVFKRSLVNVELQVSKYDDVRSTM
                     KVVLPKGWTLKNVVNHFIAWIGYTKGTFVKTEKSHDQFKIYIKNKVRPLAVFKIEETA
                     DGIITLILLSGSLVKKYTVNQGKLEFRLIKESAVVYIHLYDYIPRLFWPIYYFIQAPM
                     QKMMIHGFEVDCRIKDFQSRLKSGENMKYTK"
     gene            2266..2940
                     /gene="graR"
                     /locus_tag="RPH49_002501"
                     /gene_synonym="apsR"
     CDS             2266..2940
                     /gene="graR"
                     /locus_tag="RPH49_002501"
                     /gene_synonym="apsR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor
                     GraR/ApsR"
                     /protein_id="HDY5125614.1"
                     /translation="MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFN
                     PEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSRDNPMDQVMSMELGADDYMQKPF
                     YTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDQTIFLSKTEMIIL
                     EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGK
                     GYMAHE"
     gene            2933..3973
                     /gene="graS"
                     /locus_tag="RPH49_002502"
                     /gene_synonym="apsS"
     CDS             2933..3973
                     /gene="graS"
                     /locus_tag="RPH49_002502"
                     /gene_synonym="apsS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase GraS/ApsS"
                     /protein_id="HDY5125615.1"
                     /translation="MNNLKWVAYFLKSRMNWIFWILFLNLLMLGISLIDYDFPIDSLF
                     YIVSLNLSLTMIFLILTYFKEVKLYKHFDKDKEIEEIKHKDLAETPFQRHTVDYLYRQ
                     ILAHKDKVVDQQLQLNMHEQTITEFVHDIKTPVTAMKLLIDQEENQERKQALLFEWSR
                     INSMLDTQLYITRLESQRKDMYFDYVSLKRMVIDEIQLTRHISQVKGIGFDVDFKVDN
                     HVYTDIKWCRMIIRQILSNALKYSENYNVDISTELIDQHVALIIKDHGRGISKKDMPR
                     IFERGFTSTANRNETTSSGMGLYLVDSVKDQLGIQLQVTSTIGKGTTVKLIFPLQNEI
                     VERMSEVTNLSF"
     gene            4120..4881
                     /gene="vraF"
                     /locus_tag="RPH49_002503"
     CDS             4120..4881
                     /gene="vraF"
                     /locus_tag="RPH49_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein VraF"
                     /protein_id="HDY5125616.1"
                     /translation="MTILEVKQLTKIYGNKKMAQEVLRDINMSVEEGEFIAIMGPSGS
                     GKTTLLNVLSSIDYISQGSITLKGHKLEKLSNKALSDIRKHDIGFIFQEYNLLHTLTV
                     KENIMLPLTVQKLDKDTMLDRYEKVAEALNILDISDKYPSELSGGQRQRTSAARAFIT
                     LPSIIFADEPTGALDSKSTQDLLKRLMKMNEEIKTTIIMVTHDPVAASYANRVVMLKD
                     GQIFTELYQGDDDKHTFFKEIIRVQSVLGGINYEF"
     gene            4871..6760
                     /locus_tag="RPH49_002504"
     CDS             4871..6760
                     /locus_tag="RPH49_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125617.1"
                     /translation="MSFNEIIFKNFRQNLSHYAIYLFSLITSVVLFFSFVALKYTHSI
                     NITETYPIIKEGSQVGSYFLFFIIIAFLLYANLLFLKRRSSELALYQTLGLSKYNIIY
                     ILMFEQLLIFSITAILGITIGIFGSKILLMIVFTLLGIKEKVPIIFSFKAVFETLLLI
                     GVAYFLTAAQNLILVLKQSISELSKHNQAKQMNHNKITFEEVILGILGIILIISGYYY
                     SLRIVHYYDAFGVLMFILFATVIGAYLFFKSSVSLVFKIIKRFKKGVISVNDVMFSSS
                     IMYRIQKNAFSLTVMAIISAITLSVLCFAAISRATLSSEIKYTSPHDVTIKDQQKANQ
                     LASELNNQKIPHFYNYKEVIHTKLYKDDLFDIKAKEPYNVTITSDKYIPNTDLKRGQA
                     DLFVAEGSIKDLVKHKKHGKAVIGTKKHHVDIKLRKDINKIYFMTDVDLGGPTFVLND
                     QDYQEIRKYTKPKHIVSQFGFDLKHKKDMLALEKATNKVDKSIETRSEAISSISSLTG
                     ILLFVTSFLGISFLIAVCCIIYIKQIDETEDELENYSILRKLGFTQKDMAKGLKFKIA
                     FNFGLPLVIALSHAYFTSLAYMKLMGTTNQIPIFIVMGLYICMYAIFAITAYNHSKRT
                     IRHSI"
BASE COUNT         2557 a          890 c         1222 g         2282 t
ORIGIN      
        1 aaagaattca aaagaaaaat taaaatatag attgagcacg aagtgatttg aaataaggtt
       61 gtgaaaggga atgacaaggt cagcattaaa accatttaaa aataaacgcg ttatggttac
      121 tggacgtata caacgtgttt tgtttaaaaa ttatttagat agacatagca catttaagcc
      181 gaatgtaaga atattattaa aagatgtatt tgtttcaggt gtatcaatag atcatttatg
      241 gttatatgag acaaataaat actatgcatt ggcaatggaa cttattcatc aacgagtaaa
      301 atttagtgcg aatgttgtac cgtattacaa aataaataga aataataatt tattcgtaca
      361 agattatgga attaagcgta aaggtaggtt aattactgaa gaagcttaca atcaaaacaa
      421 tcagtatcag gataagatat atgaaaaatt accggatata gattttagac tcgaagattt
      481 ttatagtaag gaaaactaaa caacatatat aaagcaccac taaccgtagt tgatagttaa
      541 tcaattacac attagtggtg ttttattttg aatttaaatt tgataaatga ataagagtat
      601 acgcattcat ttaaaattag atgacattga taaggatgag taatgtatta ggtaaccatt
      661 aaattcgttg ttatgcgatt ctgatacaag attatgataa aatagcttta attaagaatt
      721 ttagccatca tatagtcatc gtaatattta ccatcgataa ataacttatc ttttaaaacg
      781 ccttcgattt gaaaatcggc acttttaaaa agctcgaggg caggttggtt attgagtggt
      841 acatttgctt caattcggtg tatttgattg tttaaacacc aagccataat ggcatcaaga
      901 agtgcttggc caattccacg atgttgatat aatttcttta cacctaaatc aattttagca
      961 acatgtttaa tgcgttgaaa tggtgtcgta ttaacaaagg caaagccaac gagttgttca
     1021 tcactttcag caacaaagat gactttatgt ggagaagtga tatattcttc taattgttta
     1081 ctagccgatg tgacgctagg atcatattct cctggtgtgt aaaacatata cggagattcg
     1141 tcgtatattt tcgctaacat tgaaatgaaa ttttctacat ctttgatact aactctacgt
     1201 ataatatggg ccataaaaag cctccagtat tttgaaattt taaaacattt gctactatta
     1261 taatatatat ttaaccaaaa ggtagagtaa tatgtttttt ggttacagtt taaaggagta
     1321 ttttagatga aacctaaagt tttattagca ggtggaacag ggtatattgg taagtattta
     1381 agtgaagtga ttgaaaatga tgcggaactt tttgctatat caaaatatcc agacaataaa
     1441 aaaacagatg atgttgaaat gacttggatt cagtgtgata tatttcatta cgaacaggtt
     1501 gttgcagcaa tgaatcaagt agatattgct gtattcttta tcgacccaac aaagaactct
     1561 gccaaaataa cacaatcatc agcaagagat ttaacattaa tcgcagcaga taattttggt
     1621 cgagcagctg ctatcaatca agtaaaaaaa gtaatctaca tacctgggag tcgttatgat
     1681 aatgaaacaa ttgaacgcct aggtgcatat ggtacaactg tagaaacaac aaatttagtt
     1741 tttaaacgtt ctttagttaa tgtagaatta caagtttcaa agtatgatga tgttagatca
     1801 acgatgaagg tagttttacc aaagggatgg acattaaaga acgttgtaaa ccattttatt
     1861 gcatggatag gttatactaa aggaactttt gtgaaaacag aaaaatcaca tgatcaattt
     1921 aagatatata ttaagaataa ggtgcgaccg ctcgcagtat ttaaaataga agagacagct
     1981 gatggaataa taactttaat tttattgagt ggaagtttag tgaaaaaata tacagttaat
     2041 caagggaagt tagaatttag attaatcaaa gagtcggcag tcgtttatat acatctatac
     2101 gattatatcc ctcgattatt ttggccgatt tattacttta tacaagcacc aatgcaaaaa
     2161 atgatgattc atggctttga agttgactgc cggattaaag attttcaaag tcgattaaaa
     2221 tcaggagaaa atatgaaata tactaaatga tattgggtga tatggatgca aatactacta
     2281 gtagaagatg acaatacttt gtttcaagaa ttgaaaaaag aattagaaca atgggatttt
     2341 aatgttgctg gtattgaaga tttcggcaaa gtaatggata catttgaaag ttttaatcct
     2401 gaaattgtta tattggatgt tcaattacct aaatatgatg ggttttattg gtgcagaaaa
     2461 atgagagaag tttccaatgt gccaatatta ttcttatcat ctcgtgacaa cccgatggat
     2521 caagtgatga gtatggaact tggcgcagat gattatatgc aaaagccttt ttatacaaat
     2581 gtattaattg ctaaattaca agcgatttat cgtcgtgtct atgagtttac agctgaagaa
     2641 aaacgtacat tgacttggca agatgctgtc gttgatctat caaaagacag tatacaaaaa
     2701 ggtgatcaga cgattttcct gtctaaaaca gaaatgatta ttttagaaat tcttattacc
     2761 aaaaaaaatc aaatcgtttc gagagataca attatcactg cattatggga tgatgaagca
     2821 tttgttagtg ataatacgtt aacagtaaat gtgaatcgtt tacgaaaaaa attatctgaa
     2881 attagtatgg atagtgcaat cgaaacaaaa gtaggaaaag gatatatggc tcatgaataa
     2941 tttgaaatgg gtagcttatt ttttgaaatc tcgcatgaac tggatatttt ggatattgtt
     3001 tttaaacttg cttatgttag gcattagtct tatcgattat gattttccaa tagacagttt
     3061 attttatatt gtttctttga atttaagttt aacaatgatt tttcttatat tgacatattt
     3121 taaagaagta aaattatata agcattttga caaagataaa gaaatagaag aaattaaaca
     3181 taaagattta gcggaaacgc catttcaacg tcatacagtt gattatttat atcgtcaaat
     3241 tttagcgcat aaagataaag tggtcgacca acagttacaa ttgaacatgc atgaacaaac
     3301 cattacagaa tttgtgcacg acataaaaac acctgtgaca gccatgaaat tattaattga
     3361 ccaagaagag aatcaagaaa gaaaacaagc gctattattt gaatggtcac gtattaactc
     3421 gatgttagat acgcaattgt atattacgag attagaatct caacgcaaag atatgtattt
     3481 tgattacgtg tcacttaaac gcatggtcat tgatgaaata caattaacaa gacatattag
     3541 tcaggttaaa ggtattggtt ttgatgttga ctttaaagtg gataatcatg tgtacacgga
     3601 tataaaatgg tgtcgtatga ttattagaca gattttatca aatgctttga aatatagtga
     3661 gaattataat gttgatattt caacggaatt aattgatcaa catgttgcgt taatcatcaa
     3721 ggatcacgga agaggtatta gtaaaaaaga tatgcctcga atatttgaac gtgggtttac
     3781 gtcaacggct aacagaaatg aaacgacatc ctccggcatg ggtctatact tagtggatag
     3841 tgtgaaagat caattaggaa tacaattaca agtcacttcg actattggaa aaggaacaac
     3901 ggttaaattg atcttcccat tacaaaatga aattgttgag cgcatgtcag aagtgacaaa
     3961 tctgtcattt taaacatgcg ttttgttact tagaattgat acatcatgac cacttcaacg
     4021 atataatcaa atagatgtta attaaataca aaattgaagg taagcgtgcc aaattgaata
     4081 taaaggaaat gaagttaaga taaatatagg agtgttaaag tgacaatatt agaagtaaaa
     4141 caattaacaa aaatatatgg caataagaaa atggcacaag aagttctgcg agatatcaat
     4201 atgtctgttg aagaaggtga atttattgct attatgggac cttcaggatc tggtaaaacg
     4261 accttattaa atgttttgag ttcaattgat tatatttcgc aaggttccat cacactaaaa
     4321 ggacacaaac ttgaaaagct ttcaaacaaa gcattatctg atattcgaaa gcatgatatt
     4381 ggttttattt ttcaagaata taatttactg catacattga ctgttaaaga aaatatcatg
     4441 ttaccattaa cggttcagaa attagataag gacacaatgt tagatcgtta tgaaaaagtg
     4501 gcagaagcat taaatatatt agacatcagt gataaatatc catccgaatt gtctggtggt
     4561 caaagacaac gaacatcagc tgccagagca tttataacat tgccttctat tatatttgcc
     4621 gatgaaccta caggtgcact cgattcgaaa agtacacaag atttattaaa gcgattaatg
     4681 aaaatgaatg aagagattaa gacgacgatt attatggtga cacatgatcc ggttgcagct
     4741 agctatgcaa atcgagtagt gatgcttaaa gatgggcaaa tattcacgga gttatatcaa
     4801 ggtgatgatg acaaacatac tttctttaaa gaaatcatac gtgtacaaag tgttttaggt
     4861 ggcattaatt atgagtttta atgagattat atttaaaaat ttccgccaaa atttatcaca
     4921 ttatgccatt tatctttttt cgctaattac aagtgtagtt ttgtttttta gcttcgtagc
     4981 actaaaatat actcatagca ttaacataac tgagacatat cccattatta aagaaggatc
     5041 gcaagtaggt agttactttc tattttttat cattattgcc tttttgctat atgccaattt
     5101 actatttctt aaacgtcgta gttctgaact tgcattatat caaacattag gtttatccaa
     5161 atacaacatt atatatatat tgatgtttga acaattatta atattttcaa taacagctat
     5221 attgggcatt acgattggta tctttggttc taaaatttta ttaatgatag tgtttacttt
     5281 attaggtatc aaagaaaagg ttccaattat tttcagcttt aaagcagtgt ttgagacgct
     5341 attattaatt ggcgttgctt atttcctaac tgcagctcaa aatcttatct tagtattgaa
     5401 acaatctatt tcagaactat caaagcataa tcaggctaag caaatgaatc ataataaaat
     5461 tacatttgaa gaagttatac taggaattct aggtattatt ttaatcatca gtgggtatta
     5521 ctactcttta cgcattgtac attactatga tgcatttggc gtccttatgt ttatattgtt
     5581 tgcgacagta attggggcgt atttattttt taaaagttca gtatccctgg tatttaaaat
     5641 tattaaaagg tttaaaaaag gtgtaataag tgtaaatgat gtcatgtttt cttcatctat
     5701 tatgtatcgt attcagaaaa atgcattttc acttactgtt atggcaatta tttcagctat
     5761 tactttatca gtactttgtt ttgctgctat cagtagagca actttatcaa gtgaaattaa
     5821 gtacacgtca cctcatgatg ttacgattaa agatcaacag aaggcgaatc agttagcaag
     5881 tgaattgaac aaccaaaaaa ttcctcattt ttataattat aaagaagtga ttcatacaaa
     5941 actttataag gatgacttat ttgatataaa agcaaaggaa ccatataatg taacaattac
     6001 tagtgataaa tatattccta atacggattt gaaacgtggt caggctgatt tatttgtagc
     6061 ggaaggctct attaaagatt tagtgaagca taagaaacat ggtaaggcag tgataggaac
     6121 gaaaaagcac catgtggata ttaaattacg taaagatatc aataaaattt actttatgac
     6181 tgatgttgac ttaggtggac cgacatttgt gttaaacgat caagattatc aagagataag
     6241 aaagtatact aagccaaaac acattgtttc tcaatttgga tttgatttaa aacataaaaa
     6301 agatatgtta gctttggaaa aagcaacaaa taaagttgac aaatctattg aaacaagaag
     6361 tgaagccata agttcgatat cgagtttaac gggaatattg ttatttgtaa cctcattttt
     6421 aggaattagt ttcctaattg ccgtatgttg tatcatatac attaaacaaa tagatgaaac
     6481 tgaagacgag ttagaaaatt atagtattct tagaaaactt ggatttacac aaaaagatat
     6541 ggcaaaagga ttaaaattta aaattgcgtt taattttgga ttgccattag tcattgcact
     6601 ttcacatgca tattttacat cattagcata tatgaaattg atggggacaa cgaatcaaat
     6661 accgatattt atagtaatgg gattatatat ttgtatgtat gccatttttg caataacagc
     6721 ttataatcat tctaagcgta caatcagaca ctcaatttaa tatatatagc agctttcagt
     6781 aggctagtga attaagattc atgagctata ctgaaagctt ttatttttgg atagttataa
     6841 atccgggcac gacagtttta atgtatatgt ttcaactttg taaattgtat taaatgtgag
     6901 aaaatagagc cataggcatt gaaagaaata tgaaataaga atagttagaa g
//
LOCUS       DAPSKH010000093         6559 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.094, whole genome shotgun sequence.
ACCESSION   DAPSKH010000093 DAPSKH010000000
VERSION     DAPSKH010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6559
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.094"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..507
                     /locus_tag="RPH49_002505"
     CDS             <1..507
                     /locus_tag="RPH49_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012990921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125618.1"
                     /translation="YVMMNGKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVG
                     YELHDGKQLSISDMMASQLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQS
                     SNTDVIANIEMLYQLATGINEPATELVEGLKLVTEFVQDENATQEDYTALERKLNDLK
                     ASYYSISK"
     gene            1215..1559
                     /locus_tag="RPH49_002506"
     CDS             1215..1559
                     /locus_tag="RPH49_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125619.1"
                     /translation="MSEFEVKEKTYNLPNEHRQVLNVIRNTSNKYITKTKLLNQLGYE
                     VNKANNRWLTQVITSLIINYHYPIGYSYKKDTRGYYIIKTQADKIEAIKSIKGLIEGS
                     QNRLKALEEIEV"
     gene            1594..2172
                     /locus_tag="RPH49_002507"
     CDS             1594..2172
                     /locus_tag="RPH49_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125620.1"
                     /translation="MKTNHLFEKYSDEVKGYKEEINNLESKIENTTKTIEDLSSKYKD
                     YIKVGNDNEADKTFNKISKLEDEKAKDNKRFEIKKELFNSIKREKLIDLLLNRKNIPE
                     LYQEEAQSLARELEGTIKQFNNVIDKINNMNEEYREDMYKFDSLIDQNEMKKDNLFRQ
                     RYGEVIVLYLNNFLINTKSIRFNEHKKLEVKK"
     gene            2172..2348
                     /locus_tag="RPH49_002508"
     CDS             2172..2348
                     /locus_tag="RPH49_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125621.1"
                     /translation="MQFSKTLEAINNAELDENQRLSILEALKEDVNDEEKRNVRDVPT
                     ISDLADKVNIRKNK"
     gene            2401..2928
                     /locus_tag="RPH49_002509"
     CDS             2401..2928
                     /locus_tag="RPH49_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017804627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spore coat protein"
                     /protein_id="HDY5125622.1"
                     /translation="MKLSKSKNVFYYRNSDNKLSEYQLLTQFNPAFINKKIKMCEFQI
                     ESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKARLQNYKNRSISNMVLLKTVL
                     NHYTEKEQKQVVKYMRSNGRYKPFNVIERLQVDLYQASIKQRSERQKQRNTAIENSKI
                     ARVNAYHQSSYVKVV"
     gene            2931..3272
                     /locus_tag="RPH49_002510"
     CDS             2931..3272
                     /locus_tag="RPH49_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125623.1"
                     /translation="MDKKQIKDFVCDYHKRTRSDVLIDDEINTDEFFSIGDENSNEWM
                     ADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYE
                     TLLDKIVEVIE"
     gene            3269..3838
                     /locus_tag="RPH49_002511"
     CDS             3269..3838
                     /locus_tag="RPH49_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDY5125624.1"
                     /translation="MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLK
                     KPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSG
                     KVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGD
                     DEDLDKTVQEVSNANPNHTVIVDDIPLED"
     gene            complement(3993..4697)
                     /gene="tst"
                     /locus_tag="RPH49_002512"
     CDS             complement(3993..4697)
                     /gene="tst"
                     /locus_tag="RPH49_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_111772164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic shock syndrome toxin TSST-1"
                     /protein_id="HDY5125625.1"
                     /translation="MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTND
                     NIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKV
                     DLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFD
                     KKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEK
                     PPINIDEIKTIEAEIN"
     gene            complement(5574..6134)
                     /locus_tag="RPH49_002513"
     CDS             complement(5574..6134)
                     /locus_tag="RPH49_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4888 domain-containing protein"
                     /protein_id="HDY5125626.1"
                     /translation="MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTD
                     NALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINP
                     QNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGK
                     VGEDKSNVSNRYINPKDINEIQITKK"
BASE COUNT         2439 a          812 c         1200 g         2108 t
ORIGIN      
        1 tacgtgatga tgaatgggaa gttattcggt catgtatata ttaaagattg taaagtaagg
       61 caatcatttg aattagcgtc acctaagcac actgaggggc ttataagaag catagaaggt
      121 cattatgtag gttatgaatt acatgatggt aaacagcttt ctattagtga tatgatggcc
      181 agtcaattat ttgaagatga gtattttatg tatggattac aaacatatgc agaatcaaat
      241 aatagtgatg tgtttgagta cctagaaaat ggatttgata cagatacact tgagggcatt
      301 caatcgagta atactgatgt gatagcgaat attgaaatgt tgtatcagtt agctacggga
      361 atcaatgaac cagcaacgga attagtagag ggattaaaat tagtaactga gtttgtacaa
      421 gatgagaatg cgacacaaga ggattacacg gcgttagaac gtaaattgaa tgatctaaaa
      481 gcgtcttatt atagtataag taaataatgt tatgtggggt cacatgtagt gtgtgactcc
      541 ttataaaaaa acggcaaggt ttgtacaagg tatagaagtt taaaatggta aggttttcgg
      601 aaggtgttgg cttttaaaac ccaaaagttt cccaaaggtg cgcagactct gagaacaatg
      661 aaataggaag gtgtacaagg ttaaaaaagc gaggtacaga actttaaaat agtaagtttg
      721 aggtagaaag aaaacaatgt tttataccag ggttgcaaaa tggtgagaaa aggggtaaat
      781 gcgagcaatt gaatcaagaa gaagtgaaaa acccaagctt ttccgtaggt tataagaata
      841 gtgcgatttt agataggtac gaagaattgc gtcaagaagg aaactaaagg taagtggttt
      901 ttggtattga taaaagtaat aaggttttaa taaggtataa aaaatttaaa aagataatat
      961 atgttaatgt ttgttatttt tgaagagggc aaaagttttg ttgttcgtat tttgttcgtg
     1021 taaaaaatgg gaacttaagt tctatagaaa ctactacgtt ttactacgga atttcttttg
     1081 cttattgttt taagagggat aggaatgatg ctaaacacct gatataatgc ggtttatagc
     1141 gaacataagt ttgatttaga tgtgtggaat tggtataatt agagtaagca aacaacagaa
     1201 agcgtggtga gacaatgagt gaatttgaag taaaagaaaa gacgtacaac ttaccgaatg
     1261 aacaccgcca agtactcaat gtgataagaa atacgtctaa taaatatatt actaaaacaa
     1321 agctgcttaa tcaattggga tatgaagtga ataaggctaa caatagatgg ttaacacaag
     1381 tcattacaag cttaatcatt aattatcatt atcctatcgg atatagctat aaaaaagata
     1441 ctagaggcta ttacatcatt aaaacacaag ctgataagat agaagctatc aaaagtatta
     1501 agggcttaat tgagggcagt cagaaccgtt taaaagccct agaagaaatt gaagtgtaac
     1561 atgataacta tgaaatgaaa gagggtaaca taaatgaaaa caaatcattt atttgaaaaa
     1621 tattccgatg aagtaaaagg ctacaaagaa gaaattaata atttagaatc taaaattgaa
     1681 aatactacaa aaactattga agatctatct tccaaatata aagactatat aaaagttggc
     1741 aacgataatg aggctgataa gacgtttaat aagatttcaa aattagaaga tgagaaagca
     1801 aaagataata aaagatttga aattaaaaag gaattattta acagcattaa gcgcgaaaaa
     1861 ctcatagact tattgttgaa taggaagaat attcctgagt tatatcaaga ggaagcacaa
     1921 agtttagcgc gtgaattaga aggtacaatc aaacagttta ataatgttat tgataaaatc
     1981 aacaatatga atgaagaata tcgagaagat atgtataagt tcgattcctt gatagatcaa
     2041 aatgaaatga aaaaagataa tttatttaga caacgatatg gcgaagtgat tgtactttac
     2101 ctcaacaact ttcttattaa tacaaaatca attcgtttca atgaacacaa aaaattggag
     2161 gttaagaaat aatgcaattt agtaaaacat tagaagcaat aaacaatgct gaattagatg
     2221 aaaaccaacg cttatctatt ttagaagcac ttaaagaaga tgtgaacgat gaggaaaaaa
     2281 gaaacgtaag agatgttcca actatttcag atttagctga taaagtaaat attagaaaaa
     2341 acaaatagac aaaagccaag ccttaattgg tttggcttta ttaactagtg gggtggataa
     2401 atgaaactga gtaaatctaa gaacgttttt tattatcgta atagcgacaa taaattatct
     2461 gagtatcaac tattaacgca atttaaccca gcatttatta ataaaaaaat taagatgtgt
     2521 gaattccaaa ttgaaagtat gtaccatatg agtgcgtcga ccacaacatg tgatgaaata
     2581 atgggggtcg tgtctgtctc atatccaatt gaaaaactag ttatcaaaat tattgaaaca
     2641 aaggcaagat tacaaaacta taaaaatcga tctataagta atatggtgtt gttgaaaacg
     2701 gtactaaatc attatacaga aaaagagcag aagcaagttg taaaatatat gcgttcaaat
     2761 ggacgatata agcccttcaa cgtcattgaa cgcttacagg ttgatttgta tcaagcaagt
     2821 attaaacaac gttcagaacg tcaaaaacaa agaaatacag caattgaaaa cagtaagatt
     2881 gcacgagtaa atgcatatca ccaatcttca tatgtaaaag tggtgtaaca atggataaaa
     2941 agcaaataaa agacttcgtt tgtgattatc ataagcgaac tagaagtgat gtgttgatag
     3001 atgatgaaat aaataccgat gaattctttt caataggtga tgaaaattct aatgaatgga
     3061 tggcagacga taacattgat gatcatattg taaagaatca cttagaaatg attgttgacc
     3121 aagtagctaa tgataaagag ttttatattt tcgattcttt aatacaagga cgtagtttta
     3181 aagatattag caatgtctta gagtgttcag aacaatctgt aagattatgg tatgaaacct
     3241 tattagataa aattgtggag gtgatagaat gagtgagtta acggcaaaac aagcgcgttt
     3301 tgtgaatgag tatataagaa cacttaatgt aacacaaagt gccataaaag caggctatag
     3361 cgcaaatagt gcacatgtga caggatgtag gttattaaag aagccacaca tcaagcaata
     3421 tatacaagaa caaaaagata aggttataga tgagaatgta ttaaccgcaa aagagttact
     3481 acatgtgctt acgaatgcgg cagtcggtga tgaaacagaa acgaaagaag ttgtggtcaa
     3541 acgtggagaa tataaagaga atccacaaag tggcaaagta cagttagtct ataacgaaca
     3601 tgttgaactg gtagaggtgc caattaagcc aagtgatcgt ttaaaagctc gtgatatgtt
     3661 gggtaaatac cataagttat ttacagataa gcatgatatt aacgggaatg tgcctatatt
     3721 cattaatatt ggtgaatggg atggcgatga tgaagattta gataagacgg tacaagaggt
     3781 atctaacgct aatcctaatc atactgtgat tgtggatgat ataccgttag aggattgatt
     3841 acagtaaaaa cgattatcat attgagttag tgaggattag tttactaatt caccctagct
     3901 ttatattaaa gcgttataaa gataaaaggg agaacgctta ttataattaa cggactccct
     3961 ttattaataa ttattacaga aaaagtggta aattaattaa tttctgcttc tatagttttt
     4021 atttcatcaa tatttatagg tggtttttca gtattgtatt caaacttttt agataaatca
     4081 ctttgatatg tggatccgtc attcattgtt attttccaat aaccacccgt tttatcgctt
     4141 gaacgatata atccatgtat ttgagttagc tgatgacgaa tttcaaagtc taaagttgat
     4201 atagctaatt gttttttatc gaactttggc caatacttta aggggctatc tttaccatga
     4261 accttaactt ttaaaggtag ttctattgga gtaggtaatt tttcagtatt tgtaacgcca
     4321 cttatttgga aatggatata agttccttcg ctagtatgtt ggcttttttt agttcttttt
     4381 gtgtttaagt caactttttc cccttttgta aaagcagggc tataataagg actcggaaaa
     4441 attataaggc tgatgctgcc atctgtgttt tttatacgca tagatcctaa ggaattatct
     4501 aaaacttcac tatttgtaaa agtgtcagac ccactactat accagtctag caaatccttt
     4561 atattatcgt ttgtagatgc ttttgcagtt ttgattattt gattagatga taagggaaca
     4621 ggggtaaaat ctgtagcgat tgtcgcaagc aacaaagggc ttacgataaa aaaattcatt
     4681 agtaattttt tattcatttt taattctcct tcattcaaat gtgtaaacgt ttacatatag
     4741 aatgtataaa tattatttaa atgaatcaat taaccatctc taaattattg tttaaatata
     4801 tattaattaa aaagtgtttg ttacataggg agctatatca aaaaaatata gatttaaaca
     4861 acattttaaa gttacaaata gcaaaaaaca aagtgtgagt ggtcatttaa agaatattaa
     4921 ttaatataag tttgaattag ttatattctt taaagtcact ttctagtggc gttttttacg
     4981 ctgagaaacg tcctgcgttg cagtaaggga taatattgtg taagtagata tgtttatcgt
     5041 aaatgtggat ccgtgaaata tgactttaaa catcgctggt caatctatct ttgagattgg
     5101 ccgtagatta aaaccatatg aaacaaaatg acttagtgga tggggaattt aggctatggc
     5161 ttgaaaattg gattaagcaa attatcagat aatattttta tgaaaatagc tgaaaatcca
     5221 gaattaaatg tcctaccatt ggaatatatg ggcgcatgta ttttatacta attagcaaca
     5281 ttaccgcaag aagagaaagg ataagagtat ttcactaaag gtgagaagta aaaaaacaat
     5341 tgatatgact aggagagaat tagaatacct taaaaaggaa ttgaaacaac gcgatgaaaa
     5401 aacgcacaac tccaatcaca aatgaaaaag cacaactttt tgaggagata gagagaaagt
     5461 aattaaagga agttaaaggt aaagaatctg aagtaattga gtgttacata gatccagaag
     5521 attatcactg ttcaaaagaa aagaggcagg agtaatctgc ctctcgaaaa aagttatttt
     5581 ttagtgattt gaatttcatt tatatcttta ggattgatgt atctattgct tacgtttgat
     5641 ttatcttctc ctactttacc gaatacagtc tcatctttag ggtctgtact taagattgaa
     5701 acattgtcgc cgttgttcac tatatttttt tctttcaatt tttctgttaa ttttttccat
     5761 gtattattag catcaatatt aggatagttc gaattttttc tagttatatt aatttttgta
     5821 acattttgag ggtttatttt aggattgttt gaagtactaa tattttctaa attagctgtt
     5881 ccttctatgg tattttctcc accattttct attttatacg taaccttgac attttcatta
     5941 tctgttttat cgataatatt cgcgtctttt aaagcgtctc ttacattttt ccacaatgcg
     6001 ttatctgtcg tttgctcagc ttttgcaacg ttattaatac cattataatt tgaagaagaa
     6061 tgaaaacctg aacctactgt tgttaaaact aaagcacttg ctatcaatgt ttttgttaat
     6121 agttttttat tcattttatt tcctcctata acttatttgc aatcaattac aaagtaattt
     6181 tacaattatt atttatgtaa ataaattaaa taattattaa caaatccata aaattttatc
     6241 attaaaatat aataattttg agctagaagt attcgtcatt tatgctataa tcattttaga
     6301 cacagcaatg tgttcaaaat ttcatctatt cgtaagttag ccttcgggct gactttttat
     6361 ttccattatt attcacatgt taatcttgtt gatatttagg caagtacttc ggtacttgcc
     6421 tattattata tctctatacg ataggaatcg actatatgac ttactaagtt ttatagcaaa
     6481 ataggcaatt aacgcatatg gcatttaaca ttgagttgtt atagtagttg tataatatat
     6541 agctagttcc ttataacag
//
LOCUS       DAPSKH010000094         6325 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPSKH010000094 DAPSKH010000000
VERSION     DAPSKH010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6325)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6325)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6325
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.095"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..1333
                     /locus_tag="RPH49_002514"
     CDS             <1..1333
                     /locus_tag="RPH49_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDY5125627.1"
                     /translation="VNMFLYLPNFFQNQNSEDNMYLAQRIMYQVDDILKEDMLNEYYY
                     LPKTLYNTLASPEFDDLKRTDASQVYGQDDTSEDDDNESEKADSKSADSESKGGAYLE
                     MELHEGQNSETLGNDEAREGDATDDMTDMMTKKGKGSNDTLNREEGDAVGQSQAFQLD
                     GVNKNVEIKWQIPEIEPQYVLEYQESKQDVQYEIKDLIQIIKKTIEREQRDARFNLTK
                     GRLQKDLINWFIDDQYKLFYKKQDLSKSFDATFTLLIDASASMHDKMAETKKGVVLFH
                     ETLKALNIKHEILSFSEDAFDSDEHAQPNIINEIINYDYSTFEKDGPRIMALEPQDDN
                     RDGVAIRVASERLMRRNQHQRFLIVFSDGEPSAFNYSQDGIIDTYEAVEMSRKFGIEV
                     FNVFLSQDPITEDVEQTIHNIYGQYAIFVEGVAHLPGHLSPLLKKLLLKSL"
     gene            1558..2901
                     /gene="brnQ"
                     /locus_tag="RPH49_002515"
     CDS             1558..2901
                     /gene="brnQ"
                     /locus_tag="RPH49_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDY5125628.1"
                     /translation="MNKNTWVIGFTLFAMFFGAGNLIFPPNLGLDSGQFFWPAILAFV
                     LTGIGLPLLGVIVGALDKEGYIGALNKISPKFSILFLIIIYLTIGPLFAIPRTASTSF
                     EMTITPIIHSNSSIALFIFTIIYFIVVLYICLNPSKLIDRIGSLLTPLLLITILAMII
                     KGYLDFSGNSAGKGNEALYHSNFSSFAEGFTQGYLTMDAIAAIAFSMIVVNAVKLTGI
                     TKTNQIFKQTLTAGLIAAVALIFIYISLGYIGNHMPVSDMTLDQLKSKDRNIGTYLLT
                     TMASTGFGSFGKYLLGIIVALACLTTACGLIVAVSEYFHRIVPKVSYKAFVLVFILMS
                     FIIANQGLNAVISMSIPVLSIVYPVAITVVLLILIAQFIPTKRITQQIPVIIVFILSI
                     FSVISKLGWLKINFIESLPLRAYSLEWFPVAIIATILGYLVGIFVKQDPIKYQQE"
     gene            complement(2974..4110)
                     /locus_tag="RPH49_002516"
     CDS             complement(2974..4110)
                     /locus_tag="RPH49_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDY5125629.1"
                     /translation="MTENKSFKESHPLDDFISDKELSNNTIQKEKLTIEQQKQVDTIS
                     KQINPLDNEGLLAFGSDLQKQMSQFSHQMLDEVQSKDVGPIGDTLSDLMSKLKSVNPN
                     ELNTDKPSMLKRIFSRAKSSINEIFSRMQSVSAQVDRITIQLQKHQTHLTRDIELLDT
                     LYDKNKQYFDDLSLHIIAAQQKKLQLENEKLPQLQQQAQQSTNQMDIQQVADMQQFID
                     RLDKRIYDLQLSRQIALQTAPQIRMIQNVNQALAEKIQSSILTSIPLWKNQMAIALTL
                     MRQRNAVATQRAVTDTTNDLLTANAEMLKQNAIETATENERGIVDLDTLKRTQRNIIE
                     TIEETLIIQQHGREERQLAEKELQQLEQDLKSHLVNIKGPNKQS"
     gene            complement(4142..4771)
                     /locus_tag="RPH49_002517"
     CDS             complement(4142..4771)
                     /locus_tag="RPH49_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDY5125630.1"
                     /translation="MTVRYNISHIFGVLVGIPVAFLTSIFGMIALDVSFLIDMSIGIV
                     GFLMTYLPIQKLTSRKYLNEIGLTRKDYRYIRNQLNHTHQKLRGILKTYVNIRSIKDF
                     RQINDIYQISRSIYTTVRQRPASFYKVEGFFYSHIDNALNLVDAYTRLAKMPKKSINE
                     QQKLEQTRITLDEVKRTLIADLKRLNEDDYERLDIEMELNKLHQKHHQD"
     gene            complement(4790..5059)
                     /locus_tag="RPH49_002518"
     CDS             complement(4790..5059)
                     /locus_tag="RPH49_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDY5125631.1"
                     /translation="MRHIHLQVFGRVQGVGFRYFTQRIAMNYNIVGTVQNVDDYVEIY
                     AQGDDADIERFIQGVIEGASPASNVTSHQLEELELNQKLSDFRSI"
     gene            5222..5530
                     /locus_tag="RPH49_002519"
     CDS             5222..5530
                     /locus_tag="RPH49_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDY5125632.1"
                     /translation="MWTVTKIRADYEGWWLFSDWPENIVEKYQYQDFDDMFKHYQQLI
                     NQCKVQFDNYVTGKYNIYAFYNNCDMNYCEDCEEDLQIFYSFIVLQNNEVYYKLPIID
                     "
     gene            5701..5901
                     /gene="cspA"
                     /locus_tag="RPH49_002520"
     CDS             5701..5901
                     /gene="cspA"
                     /locus_tag="RPH49_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015900294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspA"
                     /protein_id="HDY5125633.1"
                     /translation="MKQGTVKWFNAEKGFGFIEVEGENDVFVHFSAINQDGYKSLEEG
                     QAVEFEVVEGDRGPQAANVVKL"
     gene            6098..>6325
                     /gene="msa"
                     /locus_tag="RPH49_002521"
     CDS             6098..>6325
                     /gene="msa"
                     /locus_tag="RPH49_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sarA expression modulator protein Msa"
                     /protein_id="HDY5125634.1"
                     /translation="MKYLILSLVANLLVFGVLSAIGLNINILAAMMIVLVIPIMISGI
                     LFFKTNIDKTYIFFNIIFIDFYYYIYNVHLMT"
BASE COUNT         2070 a          918 c         1031 g         2306 t
ORIGIN      
        1 agtaaatatg ttcttatatt tacctaattt tttccaaaat caaaattctg aagataatat
       61 gtatctggct caaagaatta tgtatcaagt agatgatatt ttaaaagaag atatgctaaa
      121 cgaatattat tacttaccta aaacactata taatacatta gctagtccag agtttgatga
      181 tttaaagaga actgatgcaa gtcaagtcta tgggcaagat gatacttcag aagatgatga
      241 taacgaaagt gaaaaagctg actctaaatc tgcagatagt gagtcaaaag gtggcgccta
      301 tttagaaatg gagcttcacg aaggacaaaa tagtgaaaca ttaggtaatg atgaagcacg
      361 tgaaggcgat gctacagatg atatgactga tatgatgacc aaaaagggca aaggatcaaa
      421 cgatacgcta aatcgtgaag aaggcgatgc tgttggtcaa agccaagcat ttcaacttga
      481 tggtgtgaac aaaaatgtag aaataaaatg gcaaattcct gaaattgagc cacaatatgt
      541 tttagaatat caagaatcga aacaagacgt acaatatgaa atcaaagact taattcaaat
      601 tataaagaaa acgattgaac gagaacaacg agatgcacgt tttaatttaa caaaagggcg
      661 attacaaaag gatttaatta attggtttat cgacgatcaa tataaattgt tttacaaaaa
      721 acaagattta agtaaatcat ttgatgcgac atttacattg ttaattgatg cgtcagcaag
      781 tatgcatgat aaaatggctg aaacgaagaa aggtgtagtg ttattccacg agacgttaaa
      841 agcattgaac attaaacatg aaattttatc attcagtgag gatgcctttg attcagacga
      901 gcatgcacaa ccaaatatca ttaatgaaat tattaactat gattactcaa cctttgaaaa
      961 agatggccca cgtattatgg cacttgaacc tcaagatgat aatcgtgatg gtgttgctat
     1021 tagagttgca agtgaacgat taatgcgtcg aaatcaacat caacgatttt taatcgtatt
     1081 ttcagacggc gaaccgtctg catttaatta tagtcaagat ggtattattg atacgtatga
     1141 agctgtagaa atgtcacgta aatttggtat tgaagtattt aatgtatttt tgagtcaaga
     1201 tccaataact gaagatgttg aacaaacaat tcataatatt tatggtcaat atgctatttt
     1261 cgttgaaggt gttgcgcatt tacctggaca tctctctcca ttattaaaaa aattactact
     1321 taaatcttta taaataaatt taaaatatga gtttatatga aattgtgaat aaaagtcatc
     1381 agttactatt taaaaagtgg atttgaagaa ttttattttc tgacataatt tgatttaaac
     1441 aacacatgtg ttttgtttca gctatgtaca acatatttca tatagactct ttattatttt
     1501 ttgtgctaaa atatttactt gtaaattatt tcgtgtttta aaaaaaggag taactctatg
     1561 aataaaaata catgggtcat tgggtttacg ctcttcgcta tgttttttgg cgcaggcaat
     1621 ctaatttttc ctcctaatct cggattggat agtggtcaat ttttctggcc cgccatttta
     1681 gcgtttgttc taactgggat tggtttacca ttattaggtg tgattgtagg tgcacttgat
     1741 aaagaaggat atattggcgc attaaataaa atttcaccta aattttcaat attgttctta
     1801 atcatcattt atttgactat aggaccactt ttcgcaatac ctagaactgc atctacatct
     1861 tttgaaatga caattacacc aattatacat agcaatagta gtatcgcttt atttatattt
     1921 acgattatct acttcatagt cgttttgtat atttgtttaa atccatctaa gttaatcgat
     1981 cgtattggtt cattattaac accattatta ttgattacta ttttagcgat gattattaaa
     2041 ggatacttag actttagcgg taatagtgct ggaaagggca atgaagcact atatcattct
     2101 aatttttcaa gttttgctga aggctttaca caaggctatt taacaatgga tgccattgca
     2161 gcaattgctt tttcaatgat tgttgttaat gcagtaaaac taactggtat tactaaaaca
     2221 aatcaaatat tcaaacaaac tttgactgct ggtttaattg cagccgtagc tttaattttc
     2281 atatatattt cattaggtta tattggtaat catatgccag taagtgacat gacgttagat
     2341 caattgaaat ccaaagatcg aaacattggg acatatttat taacgacaat ggcttcaaca
     2401 ggatttggtt cattcggaaa atatttattg ggcatcattg tggcgctggc atgtctaact
     2461 acagcatgtg ggcttattgt tgcagtttct gaatatttcc atagaatcgt acctaaagta
     2521 tcatacaaag catttgtatt agttttcatt ttaatgagtt ttattattgc taaccaaggt
     2581 ttaaatgccg ttatctcaat gtcaattcct gtattaagca ttgtatatcc agtagcaata
     2641 actgttgtat tattaatttt aattgcccaa ttcataccga caaaacgcat tacacaacaa
     2701 attccagtta ttatcgtatt tatattgtcg attttcagtg ttattagtaa gttaggttgg
     2761 ctgaaaatta actttataga atcattgcct ctaagagcgt attctttaga gtggttccca
     2821 gtagcaatta ttgcaacgat attaggctat ctagtcggca tatttgtaaa acaagatcca
     2881 attaaatatc aacaggaata acgaataata taaaaggaag catctccaat ttaatcgtag
     2941 gatgcttcct ttttgttata tctaattcgt aatttatgat tgtttattcg gtcctttgat
     3001 gttcactaaa tgtgacttta aatcttgttc taattgttgt aattcttttt cagctaattg
     3061 tcgttcttcg cgaccgtgtt gttgaataat taatgtttct tcaattgtct caataatgtt
     3121 acgctgtgta cgtttcaatg tatcaagatc aacaatgcca cgctcatttt ctgttgcagt
     3181 ttcaatcgca ttttgtttca acatttcagc atttgctgtt aataaatcat tagttgtatc
     3241 agtgacagct cgttgtgtag caactgcatt acgctgtctc attaatgtaa gcgcaatggc
     3301 catttgattt ttccatagtg gaatacttgt caaaattgaa ctttgtatct tctcggcaag
     3361 tgcttgatta acattttgaa tcatacgaat ttgtggcgca gtttgcaaag ctatttgtct
     3421 tgaaagctgt aagtcatata tgcgtttatc tagtctatct ataaattgct gcatatctgc
     3481 aacttgttga atatccattt gattagtgga ttgctgcgct tgctgttgca attgtggtag
     3541 cttttcattt tctaattgca actttttttg ctgtgcagca atgatatgca atgataagtc
     3601 atcaaagtat tgtttgtttt tatcatatag cgtatctaat aattcaatat ctcttgttaa
     3661 atgcgtttga tgtttctgca gttgaattgt tatgcgatcg acttgagcac taactgattg
     3721 cattcttgaa aagatttcat tgatagacga ctttgctctg ctaaaaattc tttttaacat
     3781 agatggttta tcagtattta actcatttgg attaactgac tttagttttg acattaaatc
     3841 tgacaaagta tctccaatag gaccaacatc tttactttgt acttcatcca acatttgatg
     3901 tgaaaattga gacatttgtt tctgtaaatc agaaccaaac gccaataaac cttcattgtc
     3961 taaagggtta atttgtttac tgattgtgtc tacctgtttt tgttgttcaa ttgttaattt
     4021 ttctttttga atagtattat tcgataattc tttatcgctt ataaaatcat ctagtggatg
     4081 actttctttg aaacttttat tttcagtcat caatcatctc tccaatagtt gctattttac
     4141 atcaatcttg atgatgtttt tgatgtaact tatttaattc catttcaata tctaaacgtt
     4201 cataatcatc ttcgttgaga cgctttaaat cagcgattaa tgttcgtttg acctcatcca
     4261 aagtaattcg tgtttgttct aacttttgct gttcattaat tgattttttg ggcatttttg
     4321 ctagacgtgt atatgcatca accaaattta aagcattatc aatatgagaa taaaaaaagc
     4381 cttcaacttt ataaaatgat gcaggtctct gtctaactgt cgtataaata gaacgtgaaa
     4441 tttggtatat atcattaatc tgcctaaaat ctttaattga tcttatattg acatacgttt
     4501 ttaaaatacc tctaagtttt tgatgtgtat gatttaactg atttcgaata tagcgatagt
     4561 cttttctagt caaaccaatt tcgtttaaat atttgcgtga agtgagtttt tgtatcggta
     4621 ggtatgtcat taaaaagcca acaataccaa tagacatatc aattaaaaaa gatacatcaa
     4681 gtgcaatcat cccaaatatg cttgttaaaa acgctacagg aattcccact aacaccccaa
     4741 atatatgaga aatattatat ctcactgtca tcttccttta tttagcattt tatattgatc
     4801 gaaaatccga taatttttga tttagttcta actcttcaag ttgatggctt gttacatttg
     4861 atgctggtga ggcaccttca attacacctt gaataaatct ctctatatct gcgtcatccc
     4921 cttgtgcata tatctctaca tagtcatcta cattttgaac agtaccgaca atgttatagt
     4981 tcattgcaat gcgttgtgta aaatatctaa atccgacgcc ttgaacgcgt ccgaatactt
     5041 gtaaatgtat atgtctcatt tttaccacct cataatgtta ttatacgtag ttttacttaa
     5101 aaaaactaat aattactata gttactactt tgtttgtttc aagtcgtcaa acttgatttt
     5161 cagaggataa aggtataaaa ataagtatag agtttttgaa gtatggaagg ggtctttaat
     5221 aatgtggaca gttaccaaaa ttagagccga ttatgaggga tggtggttat tcagtgactg
     5281 gccagaaaac attgttgaaa aatatcaata tcaagatttt gatgacatgt ttaagcacta
     5341 tcaacaattg attaatcaat gtaaagttca gttcgataat tatgtcacag gcaaatataa
     5401 tatttatgca ttttataata attgtgacat gaactattgc gaagattgtg aagaggattt
     5461 acaaatattt tatagtttca ttgttttaca aaataatgaa gtatattata aactaccaat
     5521 aattgattaa atgaatattt tttattattg tattgcaatt tggtaataac tgcactataa
     5581 tacaagttaa gcagatgatt attccatatt gcaaagaata tttgagtgaa atttgcatgt
     5641 attttttgta atatgcgaat aagcatattg aatgaatttt agtcttggag gtttcagatt
     5701 atgaaacaag gtacagttaa atggtttaac gctgaaaaag gattcggctt tatcgaagtt
     5761 gaaggagaaa atgacgtatt cgtacatttt tcagcaatta accaagatgg ttacaaatca
     5821 ttagaagaag gtcaagctgt tgagtttgaa gtagttgaag gcgaccgcgg tccacaagcc
     5881 gcaaacgttg ttaaactata attcttagat ttgaatcatt gattttaact aacaccttac
     5941 caagaagtaa ggtgttttta tatgcttatt acaaatactt aacgcgatga gtttctcaac
     6001 caaattgaga actctttttt tatatcacca acattgtttg caatagaaaa ttatatttat
     6061 ataatataat tatggtgtac aacgacgagg tgattttatg aaatatctta tccttagttt
     6121 agttgctaat ttattagttt tcggtgtatt atctgcaatt ggtttaaata ttaatatttt
     6181 agcagcaatg atgattgtat tagtgattcc gataatgatt tctgggatat tatttttcaa
     6241 aactaatatt gataaaacat acatattttt caacatcata ttcatagact tttattatta
     6301 tatttacaat gtacatttaa tgact
//
LOCUS       DAPSKH010000095         6293 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPSKH010000095 DAPSKH010000000
VERSION     DAPSKH010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6293
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.096"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            64..1554
                     /locus_tag="RPH49_002522"
     CDS             64..1554
                     /locus_tag="RPH49_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000554504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HDY5125635.1"
                     /translation="MHRESKYIEYKKSRKGLSNDIWSTYSAFANTEGGTIYLGIEEKK
                     IEDKKVFVSVGVEDPEKMIEDFWNALYGRSKVSQNILSNKDVKIVNIENKACIEIHVP
                     EAPYSKKPIYVDNKKDLVYKRVDDADRIATEEEYKFMIVNSQDDIDTELLDNYDMSDL
                     NHESIENYRKLLLKNTNDERYANMSQLDLMIDLGAYRKDRSSKDKQYKMTTACLLFFG
                     KYNAISDRFPGFQLDYFKKTNYLDTDWKDRISSGDLGNEDLNVYSFFEKVLIKLTDNI
                     EESFSLNDGLTRQNYARDLKVAIREALVNTLMHAYYDTKQSIKIVNCEDFIEFYNPGN
                     MRINKEDFIHGGHSKDRNSILSTLFRRVGYSEKAGSGGPRIFDVVNRHKLKTPEIELT
                     DMDTNVVLWKQDLMKEFEKYPELDKKVIKYIIDYGSISKGEALKMENMTEYQFRNILK
                     KLKDDNLIKKEGEGPATKYVLIESKEADILRTKKVIKSLESFFRNK"
     gene            complement(1927..3245)
                     /gene="cstB"
                     /locus_tag="RPH49_002523"
                     /pseudo
     CDS             complement(1927..3245)
                     /gene="cstB"
                     /locus_tag="RPH49_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002488497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="persulfide dioxygenase-sulfurtransferase CstB"
     gene            3301..3438
                     /locus_tag="RPH49_002524"
     CDS             3301..3438
                     /locus_tag="RPH49_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001791883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125636.1"
                     /translation="MELKLLNKLDDDQLDLEFLQDNGLKGNVQGPMTLKEPLKSYIQK
                     S"
     gene            3435..3806
                     /locus_tag="RPH49_002525"
     CDS             3435..3806
                     /locus_tag="RPH49_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDY5125637.1"
                     /translation="MKTNILNLDNELENTEYVEGKPYVQYGIKYERNQALRNEAIKIH
                     GTTCKVCGFDFKAKYGDLGEGFIEIHHLKPMFSIKREIKVNPQKDLVPLCSNCHKMIH
                     RNTKKPLTIKELTKIVNYNSK"
     gene            3935..4555
                     /locus_tag="RPH49_002526"
     CDS             3935..4555
                     /locus_tag="RPH49_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125638.1"
                     /translation="MKFTEVEVIEHLVKAYKEAGKPTYPHENLYRGRNHSISGIGEDL
                     LGAYLISRLEGVQIFIDQPLSMIDKSLSTRYPDLLICEDNEIKNILEVKMDLGYQRKD
                     FIDYCRKKEEWISNIVGKQCVLSRKREDKIPMNIADDIKFHVVIYSENNGPKRFDEEI
                     MPIVNETCPHIEVYVLTSGQHPNLVNVNLEGININKDEFEILVNAL"
     gene            4919..6190
                     /locus_tag="RPH49_002527"
     CDS             4919..6190
                     /locus_tag="RPH49_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="HDY5125639.1"
                     /translation="MDNHIRIFDNLFQSNISKFQNLTSKSYIIRNDNEKNSYLPMVQE
                     IRELFGKEGEIFSKSIGTHPDFFGIENTNEYQYICSLFVDISGSTKLALKYSLDKVKL
                     YKNAIISSAIEIFRAFDGHIHRIQGDAVLVYFGHKELEKSDAIINAINAASLMQYFNA
                     TTLKKFFESENLEPLKIRIGIDFGDDSSVLWSKYGIDGINEITSTSIHTDLASKLQNK
                     APSNKIMIGENINKYLDIPKKFRSIKIEKNNGVDVEKRYILNTNNLGRYSMEVFEWEK
                     YLNSFSMLPPFSTENEQFYSPRDLKIRCWIIDEKNQDKYEYIERGSALKKEMNLLFKL
                     EIYNQCLEFKNIKWRVVNYGEEAKKDKELEFEMNQYEGYQYCNQKTAYTGLHFMECYL
                     YDINDKIICHDSFGLFINDNNREVRKLGIED"
BASE COUNT         2385 a          727 c         1114 g         2067 t
ORIGIN      
        1 tatggtagac ggtttgagta aattaatgga gtattttaat atttatggtt tggaggaatt
       61 gcgttgcata gagaaagtaa atatatagag tataagaaat cacgaaaagg attatctaat
      121 gatatttggt ctacgtatag tgcttttgca aatactgaag gtggtactat atatttagga
      181 attgaagaaa aaaagatcga ggacaaaaaa gtctttgttt cagttggtgt tgaagatcca
      241 gagaaaatga ttgaagattt ttggaatgca ctatatggaa gaagtaaagt tagtcaaaat
      301 attttatcaa ataaagatgt taaaattgtt aatattgaaa ataaagcgtg cattgaaatt
      361 catgtaccag aagcgcctta ttcgaagaaa ccgatatatg tagataataa aaaagattta
      421 gtatataaaa gagttgatga tgctgataga attgcgactg aagaagagta taaattcatg
      481 attgtaaatt ctcaagacga tatagataca gaattattag ataactatga catgtctgat
      541 ttaaatcacg aatctatcga aaattatagg aaacttctat taaaaaatac taatgatgag
      601 agatatgcga atatgagcca actggattta atgatagatt taggagcata tagaaaagat
      661 agaagttcga aagacaaaca gtataaaatg actacagcat gtttattatt ctttggtaag
      721 tataatgcga ttagtgatag attcccagga tttcaattag attattttaa gaaaacaaat
      781 tacctagata ctgattggaa agatagaata tcaagtggag atttaggtaa tgaagattta
      841 aacgtgtata gtttttttga aaaagtattg ataaaattaa ctgataacat tgaggaatca
      901 tttagcctaa atgatggttt gactagacaa aattatgcaa gagatttaaa agtagcaatt
      961 cgcgaagcac tggttaatac attaatgcat gcgtattatg atactaagca aagtattaaa
     1021 atagttaatt gtgaagattt tatagagttt tataatccgg gtaatatgag aataaataaa
     1081 gaagatttta ttcatggagg gcattcaaag gacagaaata gtatattatc gacgcttttc
     1141 agaagagtag gatattcaga aaaagctgga tctggaggac caaggatatt cgatgtagtt
     1201 aatagacata agcttaaaac gcctgaaata gaattaacgg acatggacac taatgtagta
     1261 ctttggaaac aagatttaat gaaggagttt gaaaaatatc ctgagttaga caaaaaagta
     1321 ataaagtata ttattgacta tggatcaata agtaagggtg aagccttaaa aatggaaaat
     1381 atgacagaat atcagtttag aaatatttta aaaaaactaa aagatgataa cttgataaaa
     1441 aaagaaggtg aaggtccggc tactaaatat gtgttaatag aatcaaaaga agctgatata
     1501 ttgcgaacta aaaaagtaat taaaagttta gagtctttct ttaggaataa ataaaaaaac
     1561 aagagatagg tgcgaagtgt ttggattata caaatgcttc gcatcttata tttattaata
     1621 aatatcatag aaaaccgtat cattaaccga tacgcagaga tgcggttttt tagacacttc
     1681 ataaagggat tttgaacgta tcagaacata tgaggtttat aggaattgct gttatgtttt
     1741 ttgatcacat caataaacaa aaaaggtatg tactatgtaa aatatttatt aaatgatata
     1801 aagcgagggt atataaatga tttttaaata gatatttatc caataatata aaaaggaact
     1861 ataagctata tctaaaagct atatctaact acttatagtc cttcttcatt agtataaata
     1921 taattattaa gaaaggtata tatctttgta accttcgttt acattaataa tgttgtgata
     1981 acctttgtgt tctaaaatac caatagctat agaacttcta atgccagact gacagtctac
     2041 ataaataaca tcgtttctat tgaaaggtaa atctgtttct aaaagtttgc cgtgtggcac
     2101 atgaaccgct tgggataagt ggccattatt ccattcatta tcattacgta catctaagac
     2161 atgtgcttca ttaccagtta tgtctttact atgaacagat tgtgtttgaa tttgagcttg
     2221 tggtaactga tatccagaca cattatcata tccaataagt tgtaaagtat gttatgtgtt
     2281 gcttttgaaa caaggtgata gtctccaatc aagttaattt cttgattata gtttagatac
     2341 cagccaattt gattgatgaa atttttatca tatggaatat tgattgtacc ttcaatatgt
     2401 ccaccatgat aagcctcctt actgcggaga tcaaaagtta atctgtttgt acttgtagct
     2461 ggataaaccg tataaggttg atataaattc ataccgaatt gattaatttt tttcatttgt
     2521 gcaaaatgat gtggtggtgc aggttggtca gaaatgagtt tatcgataaa ggtagcttca
     2581 ttattttcag aaaaagccca gttcgtttgt ttttcatagc caagcgtaga tgttggaata
     2641 gcacctaaag atttaccaca aggactacca gcgccatgac caggccaaat ttgaatgtag
     2701 tctggcaagt ctttaatact ttcaatagat ttaaacattt gttttgcgcc tatttcagat
     2761 aatccttcta ctttaacagc tttttctagt aaatcaggtc taccgatatc tcctacaaaa
     2821 ataaaatcac cactgaatag tcccattgga acttgtgctc cagcaccttc gtcagtaagt
     2881 aaaaaactta tactttctgg cgtgtgacca ggtgtatgaa gcacttttaa ttttatattt
     2941 cctacataaa tatcatcatt atgttgaaca aaatgagtgt ggttaggcat atttttataa
     3001 cctaacatgt catcactttc gcccgataca taaatactag catttaactt tatagcaaca
     3061 tctctaattc ctgaaacaaa atttgcatgt atatgtgttt cagctgcatg agtaatggtt
     3121 aaactctctt catcggcaac tcgaatatat gaagataagt cacaaatagg atcaatgatc
     3181 atggcttctc cagttttttg acaaccgatt aaataagatg cttgagataa atgtttatca
     3241 taaattgatg atagtcaatt tgttatcaag ggtgataatt atattaacta tggtaattac
     3301 atggaattaa agttattaaa caaacttgat gatgaccaat tagatttaga atttttacaa
     3361 gataatgggt taaaaggtaa tgttcaaggt cctatgactt taaaggaacc tttaaaaagt
     3421 tatatacaaa agtcttgaaa acgaatattt taaatttaga taatgagtta gaaaacactg
     3481 aatatgtcga aggtaaacca tatgtacagt acggtattaa atatgaaaga aatcaggcat
     3541 taagaaatga agctattaaa attcatggaa ctacatgtaa agtatgtgga tttgatttta
     3601 aagctaagta tggcgattta ggtgagggtt ttattgaaat tcatcattta aaaccaatgt
     3661 tttcaataaa aagagaaata aaagtaaatc cacaaaaaga tttagtccca ctatgttcta
     3721 attgccataa aatgattcat agaaatacta aaaaaccttt aacgattaaa gaattaacca
     3781 aaatagttaa ttataatagc aaataattta atattttata aactatcatt caaccctctt
     3841 aatttattag gaggtttttt gtatttatgc tttcaaatgt gtgatatact ttgtttgttg
     3901 aaatatagag tatctataga tagggtgatt gagtatgaaa ttcactgaag tggaagttat
     3961 cgaacatctt gtaaaggcat ataaagaagc aggaaagcct acttatcctc atgaaaattt
     4021 atatcgagga cgtaatcata gtatttcagg tattggagaa gacttgctgg gtgcttattt
     4081 gattagtaga ttggaaggtg tccaaatatt tattgatcag cctttatcta tgattgataa
     4141 atctttaagt acaagatatc cggatttatt aatttgtgaa gataatgaaa ttaaaaatat
     4201 actagaagtt aaaatggact taggatatca aagaaaagat tttatagatt attgccgaaa
     4261 gaaagaagaa tggatttcaa atatcgtagg aaaacagtgt gtattgtcta gaaagagaga
     4321 agacaaaatt cctatgaata tagctgatga tattaaattt catgttgtga tttacagtga
     4381 aaacaatgga ccgaagcggt ttgatgaaga aatcatgcct atcgttaatg aaacatgtcc
     4441 acatattgaa gtatatgtcc taacaagcgg tcaacaccct aatttagtaa atgttaatct
     4501 tgaaggtatt aatattaata aagatgaatt tgaaatatta gtaaatgcgt tataaaaaaa
     4561 tagagcatcc tccacgttat ggaggtgctc tgttttttat tgaaaagtat caagttaatt
     4621 aatttaatat gcttaataag ttctaccttg acctttttct ctagcttctg ttcgatctct
     4681 tatgtactca gtacatactg gattttctgt taattcatca actgtattag tttaatcaga
     4741 agacgtgtct actttgtaag cttctaagaa cttattatat gatatagcgt ttgagttttg
     4801 ttgttcttct ataaatttct gtagttattt ttcaaaaacc gcatcattaa ctgataagca
     4861 gaggcgtatc ataagtaggg gtagtattag ccaatttaat aaataaagag gtgacagaat
     4921 ggacaatcac ataagaattt ttgataattt atttcaaagt aatatttcaa aattccaaaa
     4981 ccttactagt aaatcataca ttataagaaa tgataatgaa aagaatagtt atcttcctat
     5041 ggttcaagag ataagagagt tgtttggaaa agagggagaa attttttcta aaagtatagg
     5101 aacacatcct gacttttttg gaatagaaaa tactaatgaa taccagtaca tttgttccct
     5161 gtttgtagat atatctgggt ctacaaagct agctttgaaa tatagtttgg ataaagttaa
     5221 actttataaa aatgcgataa tttctagtgc tatagaaata tttcgtgcat ttgacggtca
     5281 tattcataga atacaaggag atgcggtgct tgtttatttt ggacataaag aactggaaaa
     5341 aagtgatgca ataattaatg caatcaacgc tgcgtcatta atgcagtatt ttaacgccac
     5401 aacattaaaa aagttttttg aaagtgaaaa tttagagccg ttaaagatta gaataggaat
     5461 tgattttggt gatgattcta gtgtattgtg gtcaaaatat ggaattgatg gaattaatga
     5521 aataacttct accagtatac atactgactt agcatcaaaa ttacaaaaca aagccccttc
     5581 aaataagatt atgattggag aaaatataaa taaatatctt gatattccta aaaagtttag
     5641 aagtataaaa attgagaaga acaatggtgt tgatgttgag aaaagatata ttttaaatac
     5701 aaataatctg ggaagatatt ctatggaagt gtttgaatgg gaaaaatact tgaatagttt
     5761 ttcaatgttg cctccttttt ctacagaaaa tgaacaattt tactcaccta gagatttgaa
     5821 aataagatgt tggattattg atgaaaaaaa tcaggataaa tatgaatata ttgaaagagg
     5881 tagtgcttta aaaaaagaaa tgaatttgtt atttaaatta gaaatttata atcaatgtct
     5941 agaatttaaa aatattaaat ggagagtggt aaactacgga gaggaggcaa aaaaggacaa
     6001 ggaattagaa tttgaaatga atcagtatga agggtatcag tattgtaatc aaaagacagc
     6061 ttatacagga ttacatttta tggaatgtta tttgtacgac atcaatgata aaataatttg
     6121 tcatgatagt tttggtcttt ttataaatga taataataga gaagtgagaa aattaggaat
     6181 agaggattga gtaatgtgaa aaaagatgag tacataaagt tacatcaaag ctatctaaat
     6241 gaatatatta aatttgctga tgccaaggca ttagctatca taagtattaa tgg
//
LOCUS       DAPSKH010000096         6144 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPSKH010000096 DAPSKH010000000
VERSION     DAPSKH010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 6144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6144
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.097"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..167
                     /locus_tag="RPH49_002528"
     CDS             <1..167
                     /locus_tag="RPH49_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125640.1"
                     /translation="ETLELLESNINEFLGSEEATNLKLVNITIKEIEERTFPNNEEEF
                     NAILTLSVNK"
     gene            224..1705
                     /gene="cls"
                     /locus_tag="RPH49_002529"
     CDS             224..1705
                     /gene="cls"
                     /locus_tag="RPH49_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDY5125641.1"
                     /translation="MQFSFSNDLGTLFTIILAIAFIINLVLAFIIIFLERNRRTASST
                     WAWLFVLFVLPLIGFILYLFFGRTVSARKLNKNNGNVLTDFDALLKQQIESFDKGNYG
                     TDNKQVQKHHDLVRMLLMDQDGFLTENNKIDHFIDGNDLYDQVLQDIKNAKEYIHLEY
                     YTFALDGLGQRILKALEEKLKQGLEVKILYDDVGSKKVKMANFDHFKSLGGEVEAFFA
                     SKLPLLNFRMNNRNHRKIIVIDGQLGYVGGFNIGDEYLGLGKLGYWRDTHLRIQGDAV
                     DALQLRFILDWNSQAHRPQFEYDEKYFPKKNKSFGNAPIQIAASGPASDWHQIEYGYT
                     KMIMSAKKSVYLQSPYFIPDNSYINAIKIAAKSGVDVHLMIPCKPDHPLVYWATFSNA
                     SDLLSSGVKIYTYENGFIHSKMCLIDDEIVSVGTANMDFRSFELNFEVNAFVYDENLA
                     KDLRAAYEHDITKSKQLTEESYANRPLSVKFKESLAKLVSPIL"
     gene            1877..2785
                     /locus_tag="RPH49_002530"
     CDS             1877..2785
                     /locus_tag="RPH49_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDY5125642.1"
                     /translation="MIHLIQISNINKSFKKKRVLKNISFDIEKGTCIALIGKNGAGKS
                     TLIDILIGNVNANSGEIFDKDKLLQSENRSIMFQKTMFPDQLKVIEIINLYQSFYENP
                     LPLEEIIELTKFDSSQLNQFVNKLSGGQQRLLDFVLSLIGQPQLILLDEPTSTMDIEI
                     REYFWSIIENLKEDNRTILYTSHYIEEVERMSDKIILIENGEIILNDSTSHIRTNQQS
                     QITLSDEYIRKLKLDKDDLVIQKNHNGTIKIITSNVNDTILYLQQLHINLDDIEIQKV
                     SIVDSYFNNKKQRGSNYDTKLLENRI"
     gene            2754..3485
                     /locus_tag="RPH49_002531"
     CDS             2754..3485
                     /locus_tag="RPH49_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125643.1"
                     /translation="MILSYLKIEFKVIMRKKTTLILSILFPVIFYILFTSILELPEDV
                     KPKFYKEYMYSMTVYSLLSFSLLTFPLDIINEKQNEWRQRLMVTPFTFTSYYISKVVK
                     TMLQFAIAILVIFMVGHFYKGVAMSAVQWLESGIFLWLGASLLITFGILFSLLNDIQK
                     TSALANIVTIGLAVLGGLWFPINTFPNWLQHVAHVLPSYHLRKLGVDIASNHHINLIS
                     FAIILLYALGSILAVYCISHFKRAE"
     gene            3489..4580
                     /locus_tag="RPH49_002532"
     CDS             3489..4580
                     /locus_tag="RPH49_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDY5125644.1"
                     /translation="MKFLKDTSIAEISSILYLIFPIAGIFFNEVYGPKWLYIISVIVF
                     SLSYLILVIVNNRLNTLMFYILLIIHYFIICYFVFSVHPMLSLFFFYSAFAVPFTFKN
                     NVKKTATNFFILTMIICTIITYLFYNNYFVAMMVYYVVISLIMLDNFKKMKNREYQKE
                     IAEKNRHINTLIAEQERHRIGQDLHDTLGHVFASLSLKSELAYKLIDADVEKVKAELL
                     AINKLSRESLNKVREIIDDVKLPSFIEEIDSIRKVLKDADIDFTFENKELAQVLSPTK
                     QSMLVMITREAINNVIKHANASKVHGKLKTVNNHKLLLMIEDDGKGIDSDCEVKSISQ
                     RVQHLNGTLAVDSTNGTKIIIEISTGGIA"
     gene            4577..5179
                     /locus_tag="RPH49_002533"
     CDS             4577..5179
                     /locus_tag="RPH49_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDY5125645.1"
                     /translation="MTSLIIAEDQNMLRQAMVQLIKLHGDFEILADTDNGLDAMKLIE
                     EYNPNVVILDIEMPGMTGLEVLAEIRKKHLNIKVIIVTTFKRPGYFEKAVVNDVDAYV
                     LKERSIEELVETINKVNNGEKEYSATLMTSFFVDKNPLTPKEQIVLREIGNGLSSKEI
                     SEKLFLTDGTVRNYTSVIIDKLFADNRFDAWKKANEKGWI"
     gene            complement(5292..5480)
                     /locus_tag="RPH49_002534"
     CDS             complement(5292..5480)
                     /locus_tag="RPH49_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LapA family protein"
                     /protein_id="HDY5125646.1"
                     /translation="MNISNENTVTLIAVIIAIIIGIFLQIFFKLPLIVTAVLSILLGI
                     FVGFIVYLIVSFYNKRKN"
     gene            5619..>6144
                     /locus_tag="RPH49_002535"
     CDS             5619..>6144
                     /locus_tag="RPH49_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDY5125647.1"
                     /translation="MKSNKSLAMIVVAIIIVGVLAFQFMNHTGPFKKGTNHETVQDLN
                     GKDKVHVQRVVDGDTFIANQNGKEIKVRLIGVDTPETVKPNTPVQPFGKEASNYSKKT
                     LTNQDVYLEYDKEKQDRYGRTLAYVWISKDRMYNKELVEKGLAREKYFSPNGKYRNVF
                     IEAQNKAKQQKLNIW"
BASE COUNT         2291 a          733 c         1027 g         2093 t
ORIGIN      
        1 ctgagacttt agaattatta gaatcaaata tcaacgaatt tttaggttct gaagaagcta
       61 caaatttgaa attagtaaat attacaataa aagaaattga agaaagaaca tttccaaata
      121 atgaagaaga gtttaatgca atattaactc tatctgtaaa taaataatct ggaaagaaag
      181 gtacaaaagt tttttgtgcc tttctttata ggagaaataa actatgcaat tttcattttc
      241 aaatgattta ggaacacttt ttaccatcat tttagcaatt gcctttatca ttaatttagt
      301 tctagcgttt attattattt ttttagaaag aaatagacgt acagccagtt caacatgggc
      361 gtggttattt gtactttttg tcttaccatt gattggtttt atcctttatt tattttttgg
      421 aagaacggtt tctgcgcgta aactaaataa aaataatggg aacgtgttaa cagattttga
      481 tgcgctttta aagcagcaga ttgaaagctt tgataaaggt aattatggta cagataataa
      541 acaagttcaa aagcaccatg atttggtacg tatgttgtta atggatcaag atggcttttt
      601 aactgaaaat aataaaattg atcattttat tgacggaaat gatttatatg atcaagtttt
      661 acaagatatt aaaaatgcta aagaatacat ccatttagag tattatacat tcgctctaga
      721 tggcttaggc caaagaattt taaaagcgtt agaagagaaa ttgaaacaag gtctagaagt
      781 gaaaatttta tatgatgacg ttggttcaaa gaaagttaag atggctaatt ttgatcattt
      841 taaatcgtta ggtggagaag ttgaagcatt ttttgcttct aaattaccgt tattgaattt
      901 cagaatgaat aatagaaatc atagaaaaat catcgtaatc gatggtcaac taggttatgt
      961 cggaggattt aacattggtg atgaatatct aggtttagga aaattagggt attggagaga
     1021 tacgcattta cgtatacaag gcgatgcggt tgatgcactg cagttgcgat ttattttaga
     1081 ctggaattcg caagcacatc gacctcaatt tgaatatgat gaaaaatatt ttcctaaaaa
     1141 gaataaatca ttcggtaatg cgccaatcca gattgctgca agtggtcctg ccagtgactg
     1201 gcatcaaatt gaatatggtt atacaaaaat gattatgagc gctaagaagt cggtatattt
     1261 gcaatcgcct tatttcattc cggataactc atatataaat gccattaaaa ttgcagctaa
     1321 atcaggggta gatgttcatc tgatgattcc atgtaagcca gatcatcctt tagtttattg
     1381 ggcgacattt tcaaatgcct ctgacttatt atcaagtggt gttaaaattt atacgtatga
     1441 aaatggattt atacattcta aaatgtgctt aattgatgat gaaatcgtat cagtcggcac
     1501 agcaaatatg gactttagaa gttttgaatt aaattttgaa gtaaatgcct ttgtatatga
     1561 tgaaaatctt gctaaagatt taagagcggc ttatgaacat gatattacaa aatcaaaaca
     1621 acttactgaa gaatcttatg ctaatagacc attgtctgtt aagtttaaag aatcgttagc
     1681 taaattagtt tcgccaattt tataatttat ttgtaaggag tctcgattat agaggctctt
     1741 tttatttctg caattaatga ctataattgt attatgtaaa ccgtaaaagt gacaaatgtc
     1801 attttgaacc aatgacaaag tatcctattt taaatcgaat aaatttacta atcttaaatt
     1861 aataaaatat taagaggtga ttcatttgat tcaaatatct aatattaata aatcatttaa
     1921 gaaaaagcgt gttttaaaaa acatttcatt tgatattgaa aaaggtacct gtatcgcatt
     1981 aatcggaaaa aatggtgctg gaaaatcaac gttaattgat atattaattg gtaatgttaa
     2041 tgctaattct ggtgagatat ttgataaaga caagttatta caaagtgaaa atcgcagtat
     2101 aatgttccaa aaaacgatgt ttccagatca attaaaagtt attgagatta tcaacttata
     2161 tcaatcattt tacgaaaatc cattaccatt ggaagaaata atagaactga cgaaatttga
     2221 ttctagtcaa ctgaaccaat ttgtaaataa actttctggt ggtcaacaac gattactcga
     2281 ttttgtatta tctttaatcg gacaaccaca attgatctta ttagatgaac caacatcgac
     2341 tatggatata gaaattagag aatatttttg gtcaattatt gaaaatttaa aagaagataa
     2401 tcgaacgata ctctatacat cgcactatat tgaagaagtc gaacgtatgt cagacaaaat
     2461 tattctcatt gaaaatggag aaataatact taatgattca acgtcacata ttagaaccaa
     2521 tcagcaatct cagattacgt tatccgatga atatataaga aagttaaaac tagataaaga
     2581 tgatttagtt attcaaaaaa atcataatgg cactatcaaa attattactt caaatgtaaa
     2641 tgatacgatt ttatatcttc aacaacttca tattaatttg gatgatattg aaatacaaaa
     2701 agtctcaatt gttgattcat acttcaacaa taaaaagcaa aggggatcta attatgatac
     2761 taagttactt gaaaatcgaa tttaaagtta taatgcgtaa aaaaacaaca ttaatattat
     2821 ctattttatt tcctgttata ttctatatat tatttacttc gatattggaa ttgccggaag
     2881 atgttaaacc taaattttat aaagagtata tgtatagtat gacggtttat agtttgttaa
     2941 gttttagttt actaactttt ccattagata ttattaatga aaaacaaaat gaatggcgcc
     3001 aaagattaat ggtaacacca tttactttta ctagttatta tatttcaaaa gtagtgaaaa
     3061 ctatgctgca atttgcaata gcgatattag ttatttttat ggttggacat ttttataaag
     3121 gtgttgcaat gagtgcagtt caatggttag agtcaggaat atttttatgg ttaggtgcgt
     3181 ctctattaat aacttttggc atattatttt ctttgttaaa tgatattcaa aaaacaagtg
     3241 ctttagctaa tatcgtaaca attggtttag cagtattagg tggattgtgg tttccgataa
     3301 acacatttcc aaattggctt caacatgttg ctcatgtttt accgagctat catttgcgta
     3361 aactaggtgt agatattgct tcaaatcatc atatcaattt aatatcattt gctataatac
     3421 tcttgtatgc tttagggagt atattagcag tatattgtat tagtcatttt aaaagggcgg
     3481 aataaaatat gaaattttta aaagatactt caattgctga aatatcgtct atactttatc
     3541 tgatttttcc tattgccggt atatttttta atgaagtata tggtcccaaa tggttgtata
     3601 ttatatcagt cattgtcttt tcgttgtcgt atcttatatt agttatagta aataatagac
     3661 ttaatacatt aatgttttac attttgttga ttattcatta ttttattatt tgttattttg
     3721 ttttcagtgt acatccaatg ctaagtttgt ttttctttta tagtgctttt gccgttccat
     3781 ttacttttaa aaataatgtt aaaaaaacgg caactaattt tttcatacta acaatgatta
     3841 tatgtacaat aataacgtac ttattttata acaactattt tgttgcaatg atggtttatt
     3901 atgtcgttat atcgttaata atgctagata attttaaaaa aatgaaaaac cgtgaatatc
     3961 aaaaagaaat agcagaaaaa aatagacata ttaatacatt aattgctgaa caagagcgac
     4021 atagaattgg tcaagactta catgatacgt tagggcatgt gtttgcaagt ttatcattaa
     4081 aatcagaatt agcttataaa ctaatagatg ctgatgtaga aaaagtaaaa gctgaattat
     4141 tagcaattaa taaattatct cgtgaatcat tgaacaaagt tcgagaaatt attgatgatg
     4201 taaaattacc atcatttatt gaagagattg atagtatacg taaagtttta aaagatgctg
     4261 atattgattt tacatttgaa aataaagaat tagcgcaagt attaagtcct actaaacaat
     4321 ctatgttagt tatgattacg cgtgaagcga taaataatgt tattaaacat gcaaatgctt
     4381 caaaagttca tggtaaatta aaaactgtaa acaatcataa attactgctt atgattgaag
     4441 atgatggcaa aggtatcgat agtgattgtg aggtgaaaag tatttcacag cgtgtacaac
     4501 atttaaatgg aactttagca gtcgactcaa caaatgggac taaaataatc attgaaatct
     4561 caacaggagg aatagcatga catctttaat tattgcagaa gatcaaaata tgttacgaca
     4621 ggcaatggtt caattaatta aactacatgg tgattttgaa attttagcag atactgataa
     4681 tggtctcgat gcaatgaaac ttattgaaga atataatcct aacgttgtta ttttagatat
     4741 agaaatgcca ggcatgactg gacttgaagt tttagcggaa attagaaaaa agcatttgaa
     4801 tattaaagtg attattgtaa caacttttaa aagaccggga tactttgaaa aagcagttgt
     4861 gaatgatgtg gatgcatatg ttttaaaaga acgttctata gaagaattgg tggaaaccat
     4921 taataaagta aataacggag agaaagaata tagcgccaca ttgatgactt cattttttgt
     4981 agataaaaac ccattaacgc ccaaagaaca aattgtatta agggaaattg gcaatggttt
     5041 aagtagtaaa gaaataagtg aaaaattatt tttgacagat ggaacagtta gaaattatac
     5101 atctgttata attgataaat tatttgcaga taatcgtttt gatgcttgga aaaaggcaaa
     5161 tgaaaaaggc tggatctaaa tacaaacaaa aaagtattga gtgttttgat ttaagagact
     5221 tggaaagtga gtcaataatc aaaatcttac tcaatacttt tattttggta ctcgcaattt
     5281 agatttgtta actaattttt tcgcttatta taaaacgaaa caatcaagta aacgataaag
     5341 cctacaaaga tacccaataa aatagatagt actgccgtca ctattaatgg taatttgaaa
     5401 aatatttgta ggaaaatacc aatgataatt gcgataatta ctgcaattaa tgtgactgta
     5461 ttttcatttg aaatgttcat ttattttcac tccttaacaa taacattata tcatgctata
     5521 gctttccaaa atattgaaat atgtagatat ggctattgac gatatttctt aacttttata
     5581 tgattaatcg gaatgaaaaa agagaagtag gtggcaatat gaagtcaaat aaatcgcttg
     5641 ctatgattgt ggtagccatc attattgtag gtgtattagc atttcaattt atgaatcata
     5701 cgggtccttt caaaaagggg acgaatcatg aaactgtaca agatttaaat ggtaaagata
     5761 aagtacatgt tcaaagagtt gtggatggtg atacatttat tgcaaatcaa aatggtaaag
     5821 aaattaaagt taggcttata ggggttgata cgccagaaac ggtgaaaccg aatacgcctg
     5881 tacaaccatt tggcaaagaa gcatcaaatt atagtaagaa gacattaaca aatcaagatg
     5941 tttatttaga atatgataaa gaaaaacaag atcgctatgg tagaacattg gcgtatgtat
     6001 ggataagtaa agatcgtatg tacaataagg aattagtgga aaagggactt gctagagaga
     6061 agtatttttc accaaatggc aaatatagaa atgtatttat agaagcacaa aataaagcta
     6121 aacaacagaa attaaatatt tgga
//
LOCUS       DAPSKH010000097         5724 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPSKH010000097 DAPSKH010000000
VERSION     DAPSKH010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5724
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.098"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            126..365
                     /locus_tag="RPH49_002536"
     CDS             126..365
                     /locus_tag="RPH49_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001656966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125648.1"
                     /translation="MSDNLSLFIDYINDNIIYGSEIKREKLENLFNQFAIKNVEKNIV
                     YDELKSLDITIIESQDSYKNKLKRLFSVLLQSKKI"
     gene            complement(397..1071)
                     /locus_tag="RPH49_002537"
     CDS             complement(397..1071)
                     /locus_tag="RPH49_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS257 family transposase"
                     /protein_id="HDY5125649.1"
                     /translation="MNYFRYKQFNKDVITVAVGYYLRYTLSYRDISEILRERGVNVHH
                     STVYRWVQEYAPILYQIWKKKHKKAYYKWRIDETYIKIKGKWSYLYRAIDAEGHTLDI
                     WLRKQRDNHSAYAFIKRLIKQFGKPQKVITDQAPSTKVAMAKVIKAFKLKPDCHCTSK
                     YLNNLIEQDHRHIKVRKTRYQSINTAKNTLKGIECIYALYKKNRRSLQIYGFSPCHEI
                     SIMLAS"
     gene            1125..1496
                     /locus_tag="RPH49_002538"
                     /pseudo
     CDS             1125..1496
                     /locus_tag="RPH49_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016912861.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase family
                     protein"
     gene            2413..3156
                     /locus_tag="RPH49_002539"
     CDS             2413..3156
                     /locus_tag="RPH49_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase"
                     /protein_id="HDY5125650.1"
                     /translation="MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDE
                     QLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANE
                     YNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIM
                     PQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVN
                     KPARANQLANWGVDGIFTDNADKMVHLSQ"
     gene            3253..3681
                     /locus_tag="RPH49_002540"
     CDS             3253..3681
                     /locus_tag="RPH49_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HDY5125651.1"
                     /translation="MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAE
                     QSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAE
                     ITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS"
     gene            complement(3727..5724)
                     /gene="mecA"
                     /locus_tag="RPH49_002541"
     CDS             complement(3727..5724)
                     /gene="mecA"
                     /locus_tag="RPH49_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP2a family beta-lactam-resistant peptidoglycan
                     transpeptidase MecA"
                     /protein_id="HDY5125652.1"
                     /translation="MKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFKQVYK
                     DSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKIKTNY
                     GNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNNVELA
                     NTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTVKKMD
                     EYLSDFAKKFHLTTNETESRNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDDAVIG
                     KKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQKSIY
                     NNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPLLNKF
                     QITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVVNGNI
                     DLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKNLDNE
                     ILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISKENIN
                     LLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKDNPNM
                     MMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE"
BASE COUNT         1916 a          849 c          943 g         2016 t
ORIGIN      
        1 atattcaagt aattttattg ttttttaatt tgtcgatatt taagttgagt taaatttaaa
       61 gggtgtaatt tgttttacaa tgatgaagat aattagtcta tcaaaataaa ggggttggga
      121 ctgttatgag tgataatttg tcattattca ttgactatat caatgataat ataatctatg
      181 gtagtgaaat caaacgggag aaattagaga atttatttaa tcaatttgct ataaaaaatg
      241 ttgaaaagaa cattgtctat gatgaactga aatctttaga tattacaatc attgagtcac
      301 aggattcata taaaaataaa ttgaagagat tattttcggt tctgttgcaa agtaaaaaaa
      361 tatagctaac cactaattta tcatgtcagt gttcgcttaa cttgctagca tgatgctaat
      421 ttcgtggcat ggcgaaaatc cgtagatctg aagagacctg cggttctttt tatatagagc
      481 gtaaatacat tcaatacctt ttaaagtatt ctttgctgta ttgatacttt gataccttgt
      541 ctttcttact ttaatatgac ggtgatcttg ctcaatgagg ttattcagat atttcgatgt
      601 acaatgacag tcaggtttaa gtttaaaagc tttaattact ttagccattg ctaccttcgt
      661 tgaaggtgcc tgatctgtaa ttaccttttg aggtttacca aattgtttaa tgagacgttt
      721 gataaacgca tatgctgaat gattatctcg ttgcttacgc aaccaaatat ctaatgtatg
      781 tccctctgca tcaatggcac gatataaata gctccatttt ccttttattt tgatgtacgt
      841 ctcatcaata cgccatttgt aataagcttt tttatgcttt ttcttccaaa tttgatacaa
      901 aattggggca tattcttgaa cccaacggta gaccgttgaa tgatgaacgt ttacaccacg
      961 ttcccttaat atttcagata tatcacgata actcaatgta tatcttagat agtagccaac
     1021 ggctacagtg ataacatcct tgttaaattg tttatatctg aaatagttca tacagaagac
     1081 tcctttttgt taaaattata ctataaattc aactttgcaa cagaaccgta ttatggaata
     1141 gagatgttgg taacatttat acaggatcat tatacttaag tttaatttcg ttattacaga
     1201 accacacatt ccaaccagaa gagaaagtat gtctatttag ttatggttca ggagcagtag
     1261 gagaaatctt tagtggttca atcgttaaag gatatgacaa agcattagat aaagagaaac
     1321 acttaaatat gctagaatct agagagcaat tatcagtcga agaatacgaa acattcttta
     1381 acagatttga taatcaagaa tttgatttcg aacgtgaatt gacacaagat ccatattcaa
     1441 aagtatactt atacagtata gaagaccata tcagaacata taagatagag aaataaacta
     1501 gtggccgatt gtgcttgatg agcttgggac ataaatccta actcgaaata aataagcata
     1561 tcactaaact gattttttaa agtttacagt gatatgctta tttttttatc ttacgatttt
     1621 gtacgtgcat gcttgcctag gggtatggct cgagccatta gtctctcgca catactattc
     1681 cctcaggcgt cagcacttac aaaatcggtt gtaattttca tttttatacg cattcttact
     1741 gagattatac taataagagg aatagtaaaa gcaattctaa gtaaaattgc agataagagg
     1801 tttgttaaaa gcagttctaa gtaaaattgc agataagagg tttgttaaaa gcagttctaa
     1861 gtaaaattgc agataagagg tttgttaaaa gcagttctca gtaaaattac agataagagg
     1921 tacgttaaaa gcagttctaa gtaaaattgc agataagagg tttgttaaaa gcagttctaa
     1981 gtaaaattgc agataagagg tacgttaaaa gcaattccat gcaaaattgc tgataagggg
     2041 taagttaaaa gcagttctca gtaaaattgc agataagagg tacgttaaaa gcagttctag
     2101 gcaaaattgc agataagagg tgcgttaaaa gcagttctca gtaaaattgc tgataagggg
     2161 taagttaaaa gcaatcctaa gtaaaattgc agataagggg tacagaaaaa ctagacttga
     2221 ttacaaaatg gagcttggga cataaatgat tttttaaaaa tgagatgaga cgtagattaa
     2281 ctccataatc aatacgaatc tatcgacttc tttatttatg atattcatct ctttttaatg
     2341 gaaataaaag tgcgattaat gtgataatac agttacgtta attaaaaaaa taaaaatgca
     2401 aggagaggta atatgctaac tgtatatgga catagaggat tacctagtaa agctccggaa
     2461 aatacaattg catcatttaa agctgcttca gaagtagaag gtataaactg gttggagtta
     2521 gatgttgcaa ttacaaaaga tgaacaactg attatcattc atgatgatta tttagaacgg
     2581 actacaaata tgtccgggga aataactgaa ttgaattatg atgaaattaa agatgcttct
     2641 gcaggatctt ggtttggtga aaaattcaaa gatgaacatt tgccaacttt cgatgatgta
     2701 gtaaaaatag caaatgaata taatatgaat ttaaatgtag aattaaaagg tattactgga
     2761 ccgaatggac tagcactttc taaaagtatg gttaagcaag tggaagaaca attaacaaac
     2821 ttaaatcaga atcaagaagt gctcatttca agctttaatg ttgtgcttgt taaacttgca
     2881 gaagaaatca tgccacaata taacagagca gttatattcc atacaacttc gtttcgtgaa
     2941 gactggagaa cacttttaga ttactgtaat gctaaaatag taaacactga agatgccaaa
     3001 cttactaaag caaaagtaaa aatggtaaaa gaagcgggtt atgaattgaa cgtatggact
     3061 gtaaacaaac cagcacgtgc aaaccaactt gctaattggg gagttgatgg tatctttaca
     3121 gacaatgcag ataaaatggt gcatttgtct caatagaaag ttagaggtga gtcttacgtt
     3181 tcagtgacgg tagacttacc tttaacatgt tacatactaa aaaattaatt tgaataagaa
     3241 agagagacat atatgaaata cgatgatttt atagtaggag aaacattcaa aacaaaaagc
     3301 cttcatatta cagaagaaga aattatccaa tttgcaacaa cttttgatcc tcaatatatg
     3361 catatagata aagaaaaagc agaacaaagt agatttaaag gtatcattgc atctggcatg
     3421 catacacttt caatatcatt taaattatgg gtagaagaag gtaaatacgg agaagaagtt
     3481 gtagcaggaa cacaaatgaa taacgttaaa tttattaaac ctgtataccc aggtaataca
     3541 ttgtacgtta tcgctgaaat tacaaataag aaatccataa aaaaagaaaa tggactcgtt
     3601 acagtgtcac tttcaacata caatgaaaat gaagaaattg tatttaaggg agaagtaaca
     3661 gcacttatta ataattcata ataaaacagt gaagcaacca tcgttacgga ttgcttcact
     3721 gttttgttat tcatctatat cgtatttttt attaccgttc tcatatagct catcatacac
     3781 tttacctgag attttggcat tgtagctagc cattccttta tcttgtacat ctttaacatt
     3841 aatagccatc atcatgtttg gattatcttt atcatatgat ataaaccacc caatttgtct
     3901 gccagtttct ccttgtttca ttttgagttc tgcagtaccg gatttgccaa ttaagtttgc
     3961 ataagatcta taaatatctt ctttatgtgt tttatttacg acttgttgca taccatcagt
     4021 taatagattg atattttctt tggaaataat atttttcttc caaactttgt ttttcgtgtc
     4081 ttttaataag tgaggtgcgt taatattgcc attattttct aatgcgctat agattgaaag
     4141 gatctgtact gggttaatca gtatttcacc ttgtccgtaa cctgaatcag ctaataatat
     4201 ttcattatct aaatttttgt ttgaaatttg agcattataa aatggataat cacttggtat
     4261 atcttcacca acacctagtt ttttcatgcc tttttcaaat ttcttactgc ctaattcgag
     4321 tgctactcta gcaaagaaaa tgttatctga tgattctatt gcttgtttta agtcgatatt
     4381 accatttacc acttcatatc ttgtaacgtt gtaaccaccc caagatttat ctttttgcca
     4441 acctttacca tcgattttat aacttgtttt atcgtctaat gttttgttat ttaacccaat
     4501 cattgctgtt aatatttttt gagttgaacc tggtgaagtt gtaatctgga acttgttgag
     4561 cagaggttct tttttatctt cggttaattt attatattct tcgttactca tgccatacat
     4621 aaatggatag acgtcatatg aaggtgtgct tacaagtgct aataattcac ctgtttgagg
     4681 gtggatagca gtacctgagc cataatcatt tttcatgttg ttataaatac tcttttgaac
     4741 tttagcatca atagttagtt gaatatcttt gccatctttt ttctttttct ctattaatgt
     4801 atgtgcgatt gtattgctat tatcgtcaac gattgtgaca cgatagccat cttcatgttg
     4861 gagcttttta tcgtaaagtt tttcgagtcc ctttttacca ataactgcat catctttata
     4921 gcctttatat tctttttgtt ttaattcttc agagttaatg ggaccaacat aacctaatag
     4981 atgtgaagtc gcttttccta gaggatagtt acgactttct gtttcattag ttgtaagatg
     5041 aaattttttt gcgaaatcac ttaaatattc atccattttt ttaacggttt taagtggaac
     5101 gaaggtatca tcttgtaccc aattttgatc catttgttgt ttgatatagt cttcagaaat
     5161 acttagttct ttagcgattg ctttataatc ttttttagat acattctttg gaacgatgcc
     5221 tatctcatat gctgttcctg tattggccaa ttccacattg tttcggtcta aaattttacc
     5281 acgttctgat tttaaatttt caatatgtat gctttggtct ttctgcattc ctggaataat
     5341 gacgctatga tcccaatcta acttccacat accatcttct ttaacaaaat taaattgaac
     5401 gttgcgatca atgttaccgt agtttgtttt aattttatat tgagcatcta ctcgtttttt
     5461 atttttagat acttttttta ttttacgatc ctgaatgttt atatctttaa cgcctaaact
     5521 attatatatt tttatcggac gttcagtcat ttctacttca ccattatcgc ttttagaaat
     5581 ataactgcta tctttataaa cttgtttgaa atttttatct tcaattgcat caatagtatt
     5641 attaatttct ttatcttttg aagcataaaa atatatacca aacccgacaa ctacaactat
     5701 taaaataagt ggaacaattt ttat
//
LOCUS       DAPSKH010000098         5055 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPSKH010000098 DAPSKH010000000
VERSION     DAPSKH010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5055
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.100"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            236..1234
                     /locus_tag="RPH49_002542"
     CDS             236..1234
                     /locus_tag="RPH49_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDY5125653.1"
                     /translation="MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSE
                     RLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTAT
                     DLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTN
                     EYQGGQLAAQHLIELGHNNMIVVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTEL
                     SKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAA
                     YVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN"
     gene            1466..2347
                     /gene="rbsU"
                     /locus_tag="RPH49_002543"
     CDS             1466..2347
                     /gene="rbsU"
                     /locus_tag="RPH49_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose transporter RbsU"
                     /protein_id="HDY5125654.1"
                     /translation="MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIF
                     AIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLG
                     ASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLI
                     GEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQII
                     SGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITI
                     IGLVLILVAASVTVFIK"
     gene            2362..2766
                     /gene="rbsD"
                     /locus_tag="RPH49_002544"
     CDS             2362..2766
                     /gene="rbsD"
                     /locus_tag="RPH49_002544"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDY5125655.1"
                     /translation="MKKTAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAV
                     TKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEM
                     KSNLAHPLNKGNIRTGETTPYSNIALESNVTF"
     gene            2794..3708
                     /gene="rbsK"
                     /locus_tag="RPH49_002545"
     CDS             2794..3708
                     /gene="rbsK"
                     /locus_tag="RPH49_002545"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDY5125656.1"
                     /translation="MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGA
                     NQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKTAEAKTGQAFITVN
                     AEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKSHGV
                     TTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKT
                     VLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAID
                     FGNKASSLTVQKHGAQASIPLLEEVNQV"
     gene            complement(3805..3939)
                     /locus_tag="RPH49_002546"
                     /pseudo
     CDS             complement(3805..3939)
                     /locus_tag="RPH49_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498833.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3959..4720
                     /locus_tag="RPH49_002547"
     CDS             3959..4720
                     /locus_tag="RPH49_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDY5125657.1"
                     /translation="MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEV
                     ACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFD
                     DNQFDIVLNEAMLTMLPIAIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSL
                     SAAINVNVSPQTKLGWLDLYHQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTLKIINN
                     ALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKEH"
BASE COUNT         1697 a          914 c          860 g         1584 t
ORIGIN      
        1 tcctcatcac aataaacatt ttaaaattct agttatcata atcattaaaa ggtattaacc
       61 ttaataatat attctctcgc ctcaacctta atcgcatact ataggcgtct gtttgtagac
      121 aataaaagtc attcacgtct tcatatgtca tcaaatgttt atcatgatat gatgaatata
      181 ataatcgggt atataactgt atgattaatt acacaataaa gagaaggaat ataatatgaa
      241 aaaagtgtca attaaagatg ttgctagaga agctggtgta tcagttacaa ctgtgtcaca
      301 tattttaaat cataatgata gtcgtttttc cgcaacaacg ataaaaaacg tacatgctgt
      361 ttcagaacgt ttaggctatg cccctaataa acatgcaaaa caattgcgcg gcagtaaaat
      421 tcaaactatt ggcgtcattt tacctagctt aacaaatccg tttttctcag cactaatgca
      481 aagtattcat gaccataaac catctgatgt tgatttatgc tttttaacat ctacagcaac
      541 tgatttgtat gacaatatta aacatttaat tgatcgaggt attgacggat taattatcgc
      601 acaatacata tcatccccgg acgccctaaa taactatcta aagaaacatc atgtacctta
      661 tgtcgtactg gatcaaaatg accatcaagg ctatacagat tttgttcgga caaatgaata
      721 tcaaggtgga caacttgcag cacaacattt aatagaactc ggtcacaaca atatgatagt
      781 tgttgcacca tatgacatga tggcgaatat gtcgactcgt gtcgctggat ttgtcgatac
      841 tttgcgcgcg aatcaattgc cagaaccaca aatcgtccat actgaattat ctaagcgcgg
      901 tgggctaacc attgttgatg acatcatggt tcaatctgcc actgcaatct tcgctattaa
      961 cgatgaactc gctattggca ttttacgagg actaattgaa catggcatca gtatcccgaa
     1021 agatatctca ttaataggtt atgacgacat tgattatgca gcgtacgtct cgccaccttt
     1081 aactactgtg gcacaaccta taactgatat tggcaaaaca tctttaacct tattacttca
     1141 acgattacag cacttagata aatccattga tatgattgaa ttaccaacga ctttaaaaat
     1201 tcgtgcaaca actggctatc atctttcaaa ctaactacgt atcttccgaa atatactcat
     1261 cattgttagg cccttagcgt tgctttaatg ctgagggttt ttaatcataa ttatttcact
     1321 aagaaattaa aataataatg tatgaatttt taaatatgat ttaaacgttt tcagctttta
     1381 tgaaaacgca tgcattttac aaataaaaat ggtacgatgg cactggtaaa acgttttact
     1441 aaaaacaaat cgtgaggtgt ataacatgag cattgttgca ttacttatcg ggttaggccc
     1501 cttaattggc tggggattct tcccaacagt cgcttcaaag tttggtggta aacctgtaca
     1561 tcaaattatc ggtgctactg taggtacgtt aatcttcgct attatattag ccgtagtcac
     1621 atcaagcggc ttccctactg gaaccaattt gctattcgcc ttattatcag gtgctggttg
     1681 gggattcgga caaatcatta catttaaagc gttcgaatta gtcggttcat ctcgtgccat
     1741 gccagtcaca acagcattcc aattattagg cgcatcttta tggggtgtct ttgcattagg
     1801 aaattggcca ggcattggtc ataaaatcat tggatttaca gctttagtcg ttattctaat
     1861 tggtgcgcgt atgacagttt ggagtgaacg caaagaagca agtaacgcca aaaatttacg
     1921 tcgtgcagtg gtacttctgt taattggtga atttggatac tggttatatt cagctgcacc
     1981 gcaagcaact tctattgatg gcctaactgc ctttttacct caagcaatgg gtatggtaat
     2041 tgttgcagtc atttatggct ttatgaatat gaaagcagag aatccattcc gtaataaaat
     2101 tacgtggtta caaattattt caggtttctt ctttgcattt ggtgccttaa catatcttat
     2161 ttcagcacaa cctaatatga atggtttagc aactggattt attctttctc aaacatccgt
     2221 tgtgcttgct acattaactg gtatttattt cttaaaacaa cataaaacgt caaaagaaat
     2281 ggttattaca atcatcggct tagtactcat tttagtagcc gcttctgtta cagtatttat
     2341 aaaataagga gtgtagatgt catgaaaaaa acagctgttt taaatgaaca tatttcaaaa
     2401 gcaatcgcga caattggtca ttttgatcta ttaacgatta atgacgctgg catgccaatt
     2461 ccaaatgatc atcgtcgtat cgacctagct gtaactaaaa acttaccacg ctttattgat
     2521 gtcttagcta cagtgttaga agaaatggaa atccaaaaaa tatacttagc agaagaaata
     2581 aaagaacata accctacaca attgcaacaa attaaacaat tgatttcatc ggaaatcgaa
     2641 atcattttca ttcctcacga agaaatgaaa agtaacttag ctcacccatt aaataaaggt
     2701 aatattcgta ctggtgaaac aacgccctac tctaatattg cattagaatc gaatgttact
     2761 ttttaaaagt tataacttga aaggagcgta cacatgacca acaaagttgt tattttaggt
     2821 tcaacgaatg tcgatcaatt tttaacagtt gaaagatatg cacaaccagg cgaaacatta
     2881 catgttgaag aagcacaaaa agcattcggc ggaggtaaag gtgccaacca ggctattgcc
     2941 actgcacgca tgcaagcaga cacaacattt attactaaaa ttggcactga tggcgttgct
     3001 gatttcatct tagaagattt taaagcggct catattgata catcatatat tatcaaaaca
     3061 gctgaggcaa aaacgggcca agcctttatc actgtgaatg cagaaggaca aaacaccatc
     3121 tatgtttatg gtggtgcgaa tatgacgatg acacctgaag atgttattaa cgcaaaagac
     3181 gctataatca atgcagactt tgtcgttgca caattagaag tacccatccc ggctattata
     3241 tctgcatttg aaattgccaa gtcacatggt gtgacgacag tattaaatcc tgcaccagcg
     3301 aaagcattac ctaatgaatt attgtcacta atcgatatta ttgtgccaaa cgaaacagaa
     3361 gccgaattgt tatctgggat taaagtaact aatgaacaat ctatgaaaga caatgctaat
     3421 tactttttat ctttaggcat taagactgtt ttgattacgt taggtaagca aggtacatat
     3481 tttgctacta aaaatcaaag ccaacacatc gaagcttata aagtaaatgc gattgataca
     3541 actgctgcag gcgacacatt tattggtgca tttgtcagtc gcttaaacaa gtcgcaagat
     3601 aacttagcag atgctattga ttttggtaat aaagcgagct cactcactgt acaaaaacac
     3661 ggcgcgcaag catctattcc tctactagaa gaagtaaatc aagtttaaat gaatcaaaca
     3721 cagctatgat ttgaaggttt agcatataac atgcaacatt cgtatatcat ggctgtgctt
     3781 tttatcttta taaaacatca tctactagaa ataattttcc actaaaccta tgcttgatga
     3841 ctcatgttta gttataaatg aagtgacaat tttttgtcat ctgtttaact ttcaaattat
     3901 cgcatataaa tatgctatat taatgataat gattatcaat taataaggag gttatgttat
     3961 gtctaaagaa gccggtcata catttttagc taaattagga aaaactcgtc tacgccccgg
     4021 tggtaaagaa gcaacagatt ggttaataca acaaggggca ttttcacaag ataaacaagt
     4081 gttagaagtg gcatgtaata tgtgtacgac atctatttat ctagctcata catatggctg
     4141 tcacattcaa ggcgttgata taaataagaa agcattagaa aaagcacaag aaaatatctc
     4201 agcagcaggt cttgaatcat atattcaagt tcaacaagcg aatgctgtta aattgccctt
     4261 tgatgacaat caattcgata tcgttttaaa tgaagcaatg ttaacaatgt tacccatcgc
     4321 cataaaggaa aaagcattac gcgagtacta ccgagtctta aagcctgggg gtatcttgtt
     4381 aacacatgat attgtcatcg ttaatgaatc acatgccaca catgtagtta aatcattatc
     4441 tgcagcaatt aatgtcaatg tctcaccgca gacgaaactt ggctggttag atttatatca
     4501 tcaagctggt tttaatcatg tacattatca tactggtcca atgagtttaa tgacacctaa
     4561 aggtttaatt tatgatgaag gtattgtcgg aactttaaag attatcaaca atgctttaaa
     4621 aaaagaaaat cgaccaatgt tttgtaaaat gtttaaaacg atgactaaac tgcgaaaaga
     4681 tatgaattat attacttttg tcgctaaaaa agagcactaa atataatgcc actaactgta
     4741 ctttatatct atgtttgact gttactttaa tttctttgtg acactaatca tctacttaac
     4801 aatatcgtta tcgttgatta gtaggtcatc aattttggtt aaagactttt ataaacactc
     4861 aaacattaac actatacata cttagttagt ggcattattt ttttcttaaa attttaacat
     4921 cacgggattg gaacagaaat gatattttcg caaaatttat ttatgtccct ccccaacttg
     4981 cacattattg taagctgact ttccgccagc ttctatgttg gggccccgcc aacttgcaca
     5041 ttattgtaag ctgac
//
LOCUS       DAPSKH010000099         4814 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPSKH010000099 DAPSKH010000000
VERSION     DAPSKH010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4814)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4814)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4814
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.101"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            12..764
                     /gene="sarS"
                     /locus_tag="RPH49_002548"
     CDS             12..764
                     /gene="sarS"
                     /locus_tag="RPH49_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarS"
                     /protein_id="HDY5125658.1"
                     /translation="MKYNNHDKIRDFIIIEAYMFRFKKKVKPEVDMTIKEFILLTYLF
                     HQQENTLPFKKIVSDLCYKQSDLVQHIKVLVKHSYISKVRSKIDERNTYISISEEQRE
                     KIAERVTLFDQIIKQFNLADQSESQMIPKDSKEFLNLMMYTMYFKNIIKKHLTLSFVE
                     FTILAIITSQNKNIVLLKDLIETIHHKYPQTVRALNNLKKQGYLIKERSTEDERKILI
                     HMDDAQQDHAEQLLAQVNQLLADKDHLHLVFE"
     gene            1185..2735
                     /gene="spa"
                     /locus_tag="RPH49_002549"
     CDS             1185..2735
                     /gene="spa"
                     /locus_tag="RPH49_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal protein A"
                     /protein_id="HDY5125659.1"
                     /translation="MKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQ
                     NAFYQVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNK
                     DQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNK
                     KQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNK
                     EQQNAFYEILHLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNK
                     EQQNAFYEILHLPNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNKKP
                     GKEDGNKPGKEDGNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNKPGK
                     EDGNKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNK
                     LADKNIIKPGQELVVDKKQPANHADANKAQALPETGEENPFIGTTVFGGLSLALGAAL
                     LAGRRREL"
     gene            complement(3064..4656)
                     /locus_tag="RPH49_002550"
     CDS             complement(3064..4656)
                     /locus_tag="RPH49_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDY5125660.1"
                     /translation="MTLLTVNPFDNVGLSALVAAVPIILFLLCLTVFKMKGIYAALTT
                     LVVTLIVALFVFELPARVSAGAITEGVVAGIFPIGYIVLMAVWLYKVSIKTGQFSIIQ
                     DSIASISEDQRIQLLLIGFCFNAFLEGAAGFGVPIAICAVLLIQLGFEPLKAAMLCLI
                     ANGAAGAFGAIGLPVSIIDTFNLSGGVTTLDVARYSALTLPILNFIIPFVLVFIVDGM
                     KGIKEILPVILTVSGTYTGLQLLLTIFHGPELADIIPSLATMVVLAFVCRKFKPKNIF
                     RLEASEHKIQKRTPKEIVFAWSPFVILTAFVLVWSAPFFKKLFQPGGALESLVLKMPI
                     PNTVSDLSPKGIALRLDLIGATGTAILLTVIITILITKLKWKSAGALLVEAIKELWLP
                     ILTISAILAIAKVMTYGGLTVAIGQGIAKAGAIFPLFSPVLGWIGVFMTGSVVNNNTL
                     FAPIQATVAQQISTSGSLLVAANTAGGVAAKLISPQSIAIATAAVKKVGEESALLKMT
                     LKYSIIFVAFICIWTFILTLIF"
BASE COUNT         1838 a          881 c          709 g         1386 t
ORIGIN      
        1 gagataaaac aatgaaatat aataaccatg acaaaattag agattttata atcattgaag
       61 catatatgtt tcgttttaag aaaaaagtca agcctgaagt cgatatgact ataaaagaat
      121 ttatattact gacttattta tttcatcagc aagaaaacac acttccattt aagaagattg
      181 tttcagattt atgttataaa caatcggatt tagtacagca tataaaagta cttgtgaaac
      241 attcatatat tagtaaagtt cgaagtaaaa ttgatgagcg taatacttac atttcaatat
      301 ctgaagaaca acgagagaaa attgcagaac gtgttacatt gtttgatcaa atcattaaac
      361 aatttaatct tgcagatcaa agtgaatcac agatgatacc aaaagatagt aaagaatttc
      421 taaacttgat gatgtataca atgtatttca agaatattat caaaaagcat ctaacattaa
      481 gttttgtaga atttacaatt ctagctatta tcacttctca aaataaaaac atcgttcttc
      541 ttaaagattt aattgaaaca atccaccata aataccctca aactgttaga gctctcaata
      601 atttaaaaaa gcaaggctat ctaataaaag aacgctcaac tgaagatgaa agaaaaattt
      661 taattcatat ggatgacgcg cagcaagacc atgctgaaca attattagct caagtgaatc
      721 aattattagc agataaagat catttacatc ttgtttttga ataatatctc tattacgcaa
      781 gtgtgctgta ttctaaagta cacttgtgtt ttctattttt taataaaacc tcagcacatt
      841 atgaacaact ttctattttc tatatctctt aaaaccattt ccgaaattaa acctcagcac
      901 attcaaagcc ccactttatt cttaaaaata ttttttaact tatacgtatt aaaccgcttt
      961 cattataaaa aatatctcta tattttatct gtttttatta atcgaaatag cgtgattttg
     1021 cggttttaag ccttttactt cctgaataaa tctttgagca aaatatttat tttataagtt
     1081 gtaaaactta catttaaatt taattataaa tatagatttt agtattgcaa tacataattc
     1141 gttatattat gatgacttta caaatacata cagggggtat taatttgaaa aagaaaaaca
     1201 tttattcaat tcgtaaacta ggtgtaggta ttgcatctgt aactttaggt acattactta
     1261 tatctggtgg cgtaacacct gctgcaaatg ctgcgcaaca cgatgaagct caacaaaatg
     1321 ctttttatca agtcttaaat atgcctaact taaatgctga tcaacgcaat ggttttatcc
     1381 aaagccttaa agatgatcca agccaaagtg ctaacgtttt aggtgaagct caaaaactta
     1441 atgactctca agctccaaaa gctgatgcgc aacaaaataa cttcaacaaa gatcaacaaa
     1501 gcgccttcta tgaaattttg aacatgccta acttaaacga agcgcaacgc aatggtttca
     1561 ttcaaagtct taaagacgat ccaagccaaa gcactaacgt tttaggtgaa gctaaaaaat
     1621 taaacgaatc tcaagcaccg aaagctgaca acaatttcaa caaaaaacaa caaaatgctt
     1681 tctatgaaat cttgaacatg cctaacttga acgaagaaca acgcaatggt ttcatccaaa
     1741 gcttaaaaga tgacccaagt caaagtgcta acctattgtc agaagctaaa aagttaaatg
     1801 aatctcaagc accgaaagcg gataacaaat tcaacaaaga acaacaaaat gctttctatg
     1861 aaatcttaca tttacctaac ttaaacgaag aacaacgcaa tggtttcatc caaagcctaa
     1921 aagatgaccc aagccaaagc gctaaccttt tagcagaagc taaaaagcta aatgatgcac
     1981 aagcaccaaa agctgacaac aaattcaaca aagaacaaca aaatgctttc tatgaaattt
     2041 tacatttacc taacttaact gaagaacaac gtaacggctt catccaaagc cttaaagacg
     2101 atccttcagt gagcaaagaa attttagcag aagctaaaaa gctaaacgat gctcaagcac
     2161 caaaagagga agacaacaaa aaacctggta aagaagacgg caacaaacct ggtaaagaag
     2221 acggcaacaa acctggcaaa gaagatggca acaaacctgg caaagaagac aacaaaaagc
     2281 ctggcaaaga agacggcaac aagcctggta aagaagatgg caacaaacct ggtaaagaag
     2341 acggcaacaa gcctggtaaa gaagatggca acaaacctgg taaagaagac ggcaacaaac
     2401 ctggtaaaga agatggtaac aaacctggca aagaagacgg caacggggta catgtcgtta
     2461 aacctggtga tacagtaaat gacattgcaa aagcaaacgg cactactgct gacaaaattg
     2521 ctgcagataa caaattagct gacaaaaaca taatcaaacc tggtcaagaa cttgttgttg
     2581 ataagaagca accagcaaac catgcagatg ctaacaaagc tcaagcatta ccagaaactg
     2641 gtgaagaaaa tccattcatc ggtacaactg tatttggtgg attatcatta gcgttaggtg
     2701 cagcgttatt agctggacgt cgtcgcgaac tataaaaaca aacaatacac aacgatagat
     2761 atcattttat ccaaaccaat tttaacttat atacgttgat taacacattc ttatttgaaa
     2821 tgataagaat catctaaatg cactagcaac atcttttgtt gctcagtgca ttttttattt
     2881 tacttacttt tctaaacaac ttctgaaacg cctcaacact ttctactcta attacatata
     2941 cgacattttt agacattaaa aaatcgaact agacaagatg ctcaatgcat ttcgtactag
     3001 ttcgattcat gaataattag atttaaaatg tcatttgaat ccaagtgaca acattattta
     3061 tatttagaat attaacgtta gtataaacgt ccaaatacaa ataaaggcaa caaatataat
     3121 actgtatttt agcgtcattt ttaataatgc tgattcttca ccaacttttt taacagctgc
     3181 agtcgcaatg gcaattgatt gtggtgaaat aagtttcgct gctacaccac ctgcagtgtt
     3241 agctgccaca agtaatgaac cgcttgttga aatttgttgt gccactgtcg cttgaatagg
     3301 tgcgaataaa gtattgttat ttacaactga accagtcata aacacaccaa tccaacctaa
     3361 tactggagag aataatggga aaattgctcc agctttagca ataccttgtc caattgctac
     3421 agtcaaacca ccgtatgtca taactttagc aatagctagg atagctgaaa ttgtaaggat
     3481 cggtaaccat aattctttaa ttgcttcgac caataaagca cctgcacttt tccattttaa
     3541 cttcgtaatt aaaattgtaa taattactgt taataaaatc gctgtcccag ttgcaccaat
     3601 taaatcgaga cgcaacgcaa ttcctttagg cgataaatca ctcacagtat ttggaattgg
     3661 catttttaat actaaacttt caagcgcacc tccaggttgg aataattttt taaagaatgg
     3721 tgcactccat actaatacaa aggcagttaa aattacgaac ggactccaag caaagacaat
     3781 ttctttaggc gttcgttttt gaattttatg ttcagacgct tccaatctga aaatgttttt
     3841 cggtttaaat ttacgacaaa caaatgctaa caccaccatt gttgctagtg atggaataat
     3901 gtctgctagt tctggaccat ggaatattgt taataataat tgtaatccag tatatgtacc
     3961 actcactgtt aaaatgacag gtaaaatttc tttaatacct ttcataccat ctacaatgaa
     4021 tactaaaaca aatggaataa taaagtttaa aattggaagt gttaatgctg agtatctcgc
     4081 aacatctaat gttgtaacgc ctccacttaa gttaaacgta tcaataatac taactggtaa
     4141 accaattgca ccaaaggcac ccgccgcacc attagcaatt aaacataaca tcgctgcttt
     4201 taatggttca aatccaagtt gaattaataa tactgcacaa atcgcaattg gcacaccaaa
     4261 tcctgctgca ccttctaaaa atgcgttgaa acaaaatcca attaataata gttggattct
     4321 ttggtcctct gaaatactag caatactatc ttgaataata gaaaattgtc ctgttttaat
     4381 agaaacttta tataaccaaa ctgccattaa aacgatatat cctattggaa aaataccggc
     4441 aacaacgcct tctgtaatcg cacctgctga tacacgcgct ggtaattcaa atacaaataa
     4501 agccacaatc aatgtaacaa ccaaagttgt caatgctgca taaatgcctt tcattttaaa
     4561 aacggttaag cataataaaa ataaaataat aggtactgct gcaactaagg ctgataatcc
     4621 aacattatcg aatggattta cagtaagtag tgtcataatg actccctctc tttatataaa
     4681 atatttatca ttctgattaa tctacaacct atttcaactt atattttgcg atgatcacat
     4741 atttaaaatg taacactcct atatgtgaca ggcaatcgaa tttttacaaa aagttcacaa
     4801 aatatacaca atat
//
LOCUS       DAPSKH010000100         4737 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPSKH010000100 DAPSKH010000000
VERSION     DAPSKH010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4737
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.102"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            76..402
                     /locus_tag="RPH49_002551"
     CDS             76..402
                     /locus_tag="RPH49_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019468012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma factor antagonist"
                     /protein_id="HDY5125661.1"
                     /translation="MNLNIETTTQDKFYEVKVGGELDVYTVPELEEVLTPMRQDGTRD
                     IYVNLENVSYMDSTGLGLFVGTLKALNQNDKELYILGVSDRIGRLFEITGLKDLMHVN
                     EGTEVE"
     gene            404..883
                     /gene="rsbW"
                     /locus_tag="RPH49_002552"
     CDS             404..883
                     /gene="rsbW"
                     /locus_tag="RPH49_002552"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001190828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma B factor RsbW"
                     /protein_id="HDY5125662.1"
                     /translation="MQSKEDFIEMRVPASAEYVSLIRLTLSGVFSRAGATYDDIEDAK
                     IAVSEAVTNAVKHAYKEKNNVGIINIYFEILEDKIKIVISDKGDSFDYETTKSKIGPY
                     DKDENIDFLREGGLGLFLIESLMDEVTVYKESGVTISMTKYIKKEQVRNNGERVEIS"
     gene            858..1628
                     /gene="sigB"
                     /locus_tag="RPH49_002553"
     CDS             858..1628
                     /gene="sigB"
                     /locus_tag="RPH49_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor SigB"
                     /protein_id="HDY5125663.1"
                     /translation="MAKESKSANEVSPEQINQWIKEHQENKNTDAQDKLVKHYQKLIE
                     SLAYKYSKGQSHHEDLVQVGMVGLIGAINRFDMSFERKFEAFLVPTVIGEIKRYLRDK
                     TWSVHVPRRIKEIGPRIKKVSDELTAELERSPSISEIADRLEVSEEEVLEAMEMGQSY
                     NALSVDHSIEADKDGSTVTLLDIMGQQDDHYDLTEKRMILEKILPILSDREREIIQCT
                     FIEGLSQKETGERIGLSQMHVSRLQRTAIKKLQEAAHK"
     gene            2063..4213
                     /locus_tag="RPH49_002554"
     CDS             2063..4213
                     /locus_tag="RPH49_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDY5125664.1"
                     /translation="MDNQLINSIIEKYQFSKKQIEAVLTLLEEKNTVPFIARYRKEQT
                     GGLDEVQIKQIDDEYQYMVNLQKRKEEVIKNIEQQGLLTEELKNDILKQNKLQRVEDL
                     YRPFKQKKKTRATEAKRKGLEPLAIWMKARKHEVSIEEKAQQFINEEVQSVEDAIKGA
                     QDIIAEQISDNPKYRTKILKDMYHQGVLTSSKKKNAEDEKGIFEMYYKYSEPIKRIAN
                     HRVLAVNRGEKEKVLSVKFEFDTTTVEDFIARQEINHNNVNRSYILEAIKDSLKRLIV
                     PSIEREIHADLTEKAENHAIDVFSENLRNLLLQPPMKGKQILGVDPAFRTGCKLAVIN
                     PFGTFIAKGVIYPHPPVSKKEAAEKDFVQMVKAYDVQLIAIGNGTASRETEHFVADLI
                     KKHQLPVQFIIVNEAGASVYSASEIARDEFPDFQVEERSAVSIGRRVQDPLSELVKID
                     PKSIGVGQYQHDVNQKALENALTFVVETAVNQVGVDVNTASSSLLQYVSGLSSQIAKN
                     IIAYREENGAIKHNKELSKIKRLGAKTFEQSIGFLRIVDGSEPLDNTSIHPESYKVTY
                     QLLDKLGFGGNDLGSDALKAKLNSLDMDELAIELQVGVPTLEDIIKSLKAPNRDPRDE
                     FETPILKSDVLSIEDLKEGMKLSGTVRNVVDFGAFVDIGVKQDGLVHVSKLSKKFVKN
                     PMDIVSVGDIVDVWIYSIDKNKDKVSLTMIDPHE"
     gene            4206..4661
                     /locus_tag="RPH49_002555"
     CDS             4206..4661
                     /locus_tag="RPH49_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDY5125665.1"
                     /translation="MNNDKLQRMVENLSEEKFGRTFQHRAYFNKRLRTTGGRYLLKSH
                     DIEINPKQYEHYGEDAVVKIILHELCHYHLHIAGKGYQHKDRDFKRLSQQVGAPRFCN
                     SIESYQQRANYEYYCTKCHAKYIRIRKVDTTRMRCGHCNGKLRMKKQLK"
BASE COUNT         1812 a          600 c          933 g         1392 t
ORIGIN      
        1 atttgaaata taaatatggt ggatacagcg cttaaaatga agataaatat ttttaataag
       61 taggagtgta atgaaatgaa tcttaatata gaaacaacca ctcaagataa attttacgaa
      121 gttaaagtcg gtggagaatt agatgtttat actgtgcctg aattagaaga ggttttaaca
      181 cctatgagac aagatggaac tcgtgatatt tatgttaatt tagaaaatgt gagttatatg
      241 gattcgacag gtttaggttt attcgtaggt acattaaaag cattaaacca aaatgataaa
      301 gaactataca ttttaggtgt gtcagatcgt atcggtagac tatttgaaat tactggtctt
      361 aaggatttaa tgcatgttaa tgaaggaacg gaggtcgaat aacatgcaat ctaaagaaga
      421 ttttatcgaa atgcgcgtgc cagcatcggc agagtatgta agtttaattc gtttaacact
      481 ttctggcgtt ttttcgagag ctggtgctac atatgatgat attgaagatg ccaagattgc
      541 agttagtgaa gctgtgacaa atgcagttaa acatgcatac aaagaaaaaa acaatgtggg
      601 cattattaac atatattttg aaattttaga agataaaatt aaaattgtta tttctgataa
      661 aggtgacagt tttgattatg aaacaactaa atcaaaaata ggtccatacg ataaagacga
      721 aaatatagac tttttacgcg aaggtggcct aggtttattt ttaatcgaat ctttaatgga
      781 tgaagtgaca gtatataaag aatctggtgt gacaatcagt atgactaagt atataaaaaa
      841 agagcaggtg cgaaataatg gcgaaagagt cgaaatcagc taatgaagtt tcacctgagc
      901 aaattaacca atggattaaa gaacaccaag aaaataagaa tacagatgca caagataagt
      961 tagttaaaca ttaccaaaaa ctaattgagt cattggcata taaatattct aaaggacaat
     1021 cacatcacga agatttagtt caagttggta tggttggttt aataggtgcc ataaatagat
     1081 tcgatatgtc ctttgaacgg aagtttgaag cctttttagt acctactgta atcggtgaaa
     1141 tcaaaagata tctacgagat aaaacttgga gtgtacatgt tccgagacgt attaaagaaa
     1201 ttgggccaag aatcaaaaaa gtgagcgatg aactaaccgc tgaattagag cgttcacctt
     1261 ctatcagtga aatagctgat cgattagaag tttcagaaga agaagtgtta gaagcaatgg
     1321 aaatgggaca aagttataat gcgttaagtg ttgatcattc cattgaagct gataaagatg
     1381 gttcaactgt tacgctatta gatattatgg ggcaacaaga tgaccattat gacttaactg
     1441 aaaaacgtat gattttagaa aaaatattac ctatattatc tgatcgcgaa cgagaaatca
     1501 tacaatgtac gtttattgaa ggattgagtc aaaaagagac aggtgagcgt atcggtttaa
     1561 gtcaaatgca tgtatcacga cttcagagaa cggcaattaa gaaattacaa gaagcagcac
     1621 ataaatagaa tttgcttatt aatgatacgt tttataatga aaaatccata taattatccc
     1681 ttgattatta aattgaaatc gaggggtatt tttaatttaa ttaaggtttt cgaattaatg
     1741 cgttattaac gtagtttaat gtgtatccac ataaatgtcg cgatatagta ttaataattt
     1801 aagtgaagaa gatatctaat tgtcggttta attaagtgga ttgctattag aataaaaaaa
     1861 gtaggcttag attatgaaat ttaggaaatg atggtgtgtc attttcaata atcttagtgc
     1921 attttaaaat gttgtatgac ctaataattc atttttaaag ttttggaagt taaaattgca
     1981 ttaagtatca taccttaata gaagtatttt agaatatgtt aaaataaatg agtaaattta
     2041 agaaaaagtg tgggttaagt aaatggacaa tcaattgatt aattcaatca tagagaaata
     2101 tcaatttagt aaaaaacaaa ttgaagcagt gttaacactg ctagaagaaa aaaatacagt
     2161 accatttatt gcgaggtatc gaaaagagca aactggtgga ctagatgaag ttcaaataaa
     2221 gcaaattgat gacgaatacc aatatatggt caatttacaa aaacgtaaag aagaagttat
     2281 caaaaatata gaacagcaag gattacttac tgaggaatta aagaacgata ttttaaaaca
     2341 gaacaaatta caacgtgttg aagacctata tagacctttt aaacaaaaga aaaagacaag
     2401 ggcaactgag gcgaaacgta aagggttaga accattagcg atatggatga aggcacgtaa
     2461 acatgaagtc tcaattgaag aaaaagcaca acaatttata aatgaagaag tgcaatcggt
     2521 tgaagatgct atcaaaggtg cacaagatat tattgcggaa caaatttcag ataatcctaa
     2581 atatagaaca aaaattttaa aagatatgta tcatcaaggt gtgttaactt catctaaaaa
     2641 gaaaaatgct gaagatgaaa aaggtatttt tgaaatgtac tataaatata gtgagccaat
     2701 taaacgcatt gctaaccata gagttttagc tgttaatcgt ggtgaaaaag agaaagtatt
     2761 atctgtaaag tttgaattcg atacgacaac agtagaggat ttcattgcac gtcaagaaat
     2821 caatcataac aatgtaaatc gcagttatat tttagaggcg attaaagata gcttgaaacg
     2881 cttaattgtc ccttcgatag agcgtgaaat ccatgctgat ttaactgaaa aagctgaaaa
     2941 tcatgcaata gatgttttta gtgaaaactt aagaaatcta ttactgcaac ctccaatgaa
     3001 aggtaaacaa atattaggcg tagatccagc atttagaaca ggttgtaaat tagcagtcat
     3061 taacccattc ggtactttta tagcaaaagg tgtgatttat ccgcatccac cagtttctaa
     3121 aaaagaggca gcagagaagg attttgtaca aatggttaaa gcgtatgatg tgcaattaat
     3181 tgcaattggc aatggtactg caagtcgtga aacagaacat tttgttgcag atttaattaa
     3241 aaagcatcag ttgccagtac aattcatcat tgtcaatgaa gcgggcgctt cagtatactc
     3301 agcatcagaa attgctagag atgaatttcc tgattttcaa gtggaagaaa gaagtgccgt
     3361 atcaattgga cgacgcgttc aagatccatt aagtgaatta gttaaaatcg atcctaaatc
     3421 tattggtgtc ggacaatacc agcatgatgt taatcaaaaa gcactagaaa atgcattaac
     3481 tttcgttgtt gaaacagcag ttaaccaagt aggtgttgat gtcaatacag catcatcatc
     3541 attattacaa tatgtgtctg gtctaagttc gcaaattgct aaaaatataa ttgcatatag
     3601 agaagaaaat ggcgcaataa agcataataa agagttaagc aagattaagc gtttgggtgc
     3661 taaaactttt gagcagagta taggattttt aagaatagta gacgggtcag agccattgga
     3721 taatacatcg attcatcccg aaagctataa agtaacgtat cagttattag ataaactcgg
     3781 atttggtggt aatgatttag gtagtgatgc attaaaagct aaattaaatt cattggatat
     3841 ggatgaactg gcgattgaat tacaagtcgg tgtacctaca ttagaggata ttattaaatc
     3901 cttgaaagca cctaatcgag atccaaggga cgagtttgaa acaccaatcc ttaaatccga
     3961 tgtgctatca attgaagatt taaaagaagg aatgaaattg agtggcacgg ttagaaatgt
     4021 agtagatttt ggagcatttg tagatatagg tgttaaacaa gatggacttg tccatgtttc
     4081 gaaactttct aagaagttcg taaaaaatcc aatggatatt gtcagtgtcg gtgatatcgt
     4141 tgacgtttgg atttacagta ttgacaaaaa taaagacaaa gtatcattaa cgatgattga
     4201 tccacatgaa taatgacaaa cttcagcgaa tggtcgagaa cctttcggaa gaaaaatttg
     4261 gacgtacgtt tcaacatcgt gcatatttta ataaaaggtt acgtacaaca ggcggacgtt
     4321 atcttttaaa gtctcatgat attgagatta atccaaaaca atatgagcat tatggagaag
     4381 atgctgttgt aaaaattata ctgcacgaat tgtgtcatta tcacttgcat attgctggta
     4441 aaggttatca gcataaagat cgagatttta aacgattgag ccaacaggtt ggagcaccta
     4501 gattttgtaa cagcatcgaa agctatcaac aacgggcaaa ttatgaatat tattgcacta
     4561 aatgtcatgc aaaatatata cgtatccgta aagttgatac gactcgtatg cgttgtggac
     4621 attgcaatgg aaaattaaga atgaaaaaac aattgaaata agtacaatac aaatagagct
     4681 aattcatgta tatgtaagat tatttatgag ttgtatggaa tttatataga atttatc
//
LOCUS       DAPSKH010000101         4359 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPSKH010000101 DAPSKH010000000
VERSION     DAPSKH010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4359
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.103"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(267..650)
                     /locus_tag="RPH49_002556"
     CDS             complement(267..650)
                     /locus_tag="RPH49_002556"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015901315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDY5125666.1"
                     /translation="MIRTMMNAKIHRARVTESNLNYVGSITIDSDILEAVDILPNEKV
                     AIVNNNNGARFETYVIAGERGSGKICLNGAASRLVEVGDVVIIMTYAQLNEEEIKNHA
                     PKVAVMNEDNVIIEMIHEKENTIVL"
     gene            complement(652..1503)
                     /locus_tag="RPH49_002557"
     CDS             complement(652..1503)
                     /locus_tag="RPH49_002557"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDY5125667.1"
                     /translation="MTKLITTVKEMQHIVKAAKRSGTTIGFIPTMGALHDGHLTMVRE
                     SVSTNDITVVSVFVNPLQFGPNEDFDAYPRQIDKDLELVSEVGADIVFHPAVEDMYPG
                     ELGIDVKVGPLADVLEGAKRPGHFDGVVTVVNKLFNIVMPDYAYFGKKDAQQLAIVEQ
                     MVKDFNHAVEIIGIDIVREADGLAKSSRNVYLTEQERQEAVHLSKSLLLAQALYQDGE
                     RQSKVIIDRVTEYLESHISGRIEEVAVYSYPQLVEQHEITGRIFISLAVKFSKARLID
                     NIIIGAE"
     gene            complement(1496..2314)
                     /gene="panB"
                     /locus_tag="RPH49_002558"
     CDS             complement(1496..2314)
                     /gene="panB"
                     /locus_tag="RPH49_002558"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDY5125668.1"
                     /translation="MKTVSQLIDMKQKQTKISMVTAYDFPSAKQVEAAGIDMILVGDS
                     LGMTVLGYESTVQVTLADMIHHGRAVRRGAPNTFVVVDMPIGAVGISMTQDLNHALKL
                     YQETNANAIKAEGAHITPFIEKATAIGIPVVAHLGLTPQSVGVMGYKLQGATKEAAEQ
                     LILDAKNVEQAGAVALVLEAIPNDLAEEISKHLTIPVIGIGAGKGTDGQVLVYHDMLN
                     YGVEHKAKFVKQFADFSVGVDGLKQYDQEVKSGAFPSEEYTYKKKIMNEVNNND"
     gene            2387..3247
                     /locus_tag="RPH49_002559"
     CDS             2387..3247
                     /locus_tag="RPH49_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDY5125669.1"
                     /translation="MLSVAIIGPGAVGTTIAYELQQSLPHTTLIGRHAKTITYYTVPH
                     APAQDIVVKGYEDVTNTFDVIIIAVKTHQLDAVIPHLTHLAHEDTLIILAQNGYGQLE
                     HIPFKNICQAVVYISGQKKGDVVTHFRDYQLRIKDNALTRQFRDLVQDSQIDIVLEAN
                     IQQAIWYKLLVNLGINSITALGRQTVAIMHNPEIRTLCRQLLLDGCRVAQAEGLNFSE
                     QTVDTIMTIYQGYPDEMGTSMYYDIVHQQPLEVEAIQGFIYRRAREHNLDTPYLDTIY
                     SFLRAYQQNM"
     gene            complement(3333..4037)
                     /gene="budA"
                     /locus_tag="RPH49_002560"
     CDS             complement(3333..4037)
                     /gene="budA"
                     /locus_tag="RPH49_002560"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDY5125670.1"
                     /translation="MTNVLYQHGTLGTLMAGLLEGTATINELLEHGNLGIATLTGSDG
                     EVIFLDGKAYHANEHKEFIELKGDEKVPYASITNFKASKTFPLQQLSQDDVFAQIKNE
                     MLSENLFSAVKIYGTFKHMHVRMMPAQQPPYTRLIDSARRQPEEKRQDIRGAIVGFFT
                     PELFHGVGSAGFHIHFADDERAYGGHVLDFEVDDVVVEIQNFETFQQHFPVNNETFVK
                     AKIDYKDVAEEIREAE"
BASE COUNT         1324 a          935 c          621 g         1479 t
ORIGIN      
        1 tttttacttc acgaaactaa acaacatgtc attaacttat ctcgttaagt taagaattct
       61 attttctacc aaataaattc tgaatactgt tttagataat caattcgcaa aactatttct
      121 ttataaatat gtccatcatt taacactgat aaaattgcaa cgataatacc tttacttcta
      181 ttacgctaac ccaattggca taaaaataaa aacccctaat ggataactac attgttatct
      241 actagaggtt tctaacttat actattttat aacactatcg tattttcttt ttcatgaatc
      301 atttcaataa tgacattgtc ttcattcatt actgctactt taggtgcatg gtttttaatt
      361 tcttcttcat tcaactgtgc ataagtcatg attatgacta catcgcctac ttcaacaagt
      421 cttgatgctg caccgttcaa acaaatttta ccactacctc tttcaccagc tattacgtat
      481 gtttcaaaac gtgcaccatt attattattc acgatggcta ctttttcatt tggcaagatg
      541 tctaccgctt ccaaaatatc tgaatcaatc gtaatactac ctacataatt taaatttgac
      601 tcagtcactc ttgctctatg aattttagca ttcatcattg ttcttatcac tttattcagc
      661 tccaattatt atattatcta ttaaacgcgc ttttgaaaat ttgacagcta acgagataaa
      721 tatgcgtcca gttatttcgt gttgttctac taattgagga taactataaa cagcaacttc
      781 ttcaatgcgt ccacttatat gtgattcaag atattcagta accctgtcta taattacttt
      841 actttgacgt tcaccgtctt gatacaacgc ttgtgctaat agcaaacttt tacttaaatg
      901 taccgcttct tgtcgttctt gctccgttaa ataaacattt cttgaacttt tcgccaaacc
      961 atctgcttct cgaacgatat caataccaat aatttcaacg gcatgattga agtcttttac
     1021 catttgctcg acaatagcca attgctgggc atctttttta ccaaaataag cataatccgg
     1081 cataacaata ttaaatagct tattaactac tgttaccacc ccatcaaaat gccctggacg
     1141 cttcgctcct tctaacacat cagctaatgg acctactttg acatcaatac ctaattcacc
     1201 tggatacata tcttctactg caggatgaaa aacaatgtcc gcccctactt ctgatactaa
     1261 ttctaaatct ttatcaattt gtctcggata agcatcgaaa tcttcgtttg gaccaaattg
     1321 taatggatta acaaatacac tcacaactgt aatatcattt gtactaactg attcgcgtac
     1381 catcgttaaa tgtccatcat gtaaggcacc cattgttggg ataaaaccaa tcgttgttcc
     1441 tgagcgtttg gctgctttaa caatgtgttg catctctttt accgtagtaa tcagcttagt
     1501 cattgttatt aacctcattc ataattttct ttttatacgt atattcttct gatggaaatg
     1561 caccagattt aacttcttga tcgtattgtt ttaaaccatc cacaccaaca ctaaaatcag
     1621 caaattgctt cacaaatttc gctttatgtt caacaccata atttaacata tcgtgataaa
     1681 ccaatacttg accatctgta ccttttcctg caccaatacc aatgactgga attgttaagt
     1741 gcttgctaat ttcttctgct aaatcatttg gaattgcttc aagtactaac gcaactgcac
     1801 cagcttgttc tacatttttc gcatctaaaa taagttgctc cgctgcttct ttcgttgcac
     1861 cttgtaattt ataccccata acgccaacac tttgaggtgt taatcctaaa tgtgcaacaa
     1921 caggaatacc aattgccgtt gctttttcaa taaatggtgt aatatgcgct ccttctgctt
     1981 taattgcatt tgcattcgtc tcctgataaa gctttagagc atgatttaag tcttgtgtca
     2041 tagagatgcc tactgcacca atcggcatat caacaactac aaatgtattt ggtgcgcctc
     2101 ttcttactgc acgaccgtga tgaatcatat ctgctaacgt cacttgtacg gtactttcat
     2161 aacctaatac agtcatacca agtgaatccc caacaagaat catatcaata cccgctgctt
     2221 ccacttgttt agcacttgga aaatcataag ctgttaccat agaaatttta gtttgctttt
     2281 gtttcatatc tattaattga cttactgttt tcaatgttat tcaacctctt tttgcagtat
     2341 tattagaaat agtataatga atcttttata gaaaggaaag aagaagatgt tatcagttgc
     2401 gattatcggc ccaggcgctg tcggtacaac tattgcctat gaattacaac aatcattgcc
     2461 tcatacaacg cttatcggga gacacgccaa aacaataaca tattatactg taccacatgc
     2521 acctgcacaa gatattgttg tgaaaggtta tgaagatgtc acaaacacat ttgatgttat
     2581 tattattgca gtcaaaacac atcaacttga tgcagttatt cctcatttaa ctcatcttgc
     2641 acatgaggac acgctcatca ttttagccca aaatggttat ggtcaactcg aacatattcc
     2701 atttaaaaac atatgccaag cagttgtcta tataagtggt caaaagaaag gcgatgttgt
     2761 tacgcacttc agagattatc aattacgtat aaaagataat gcattaacac gacaatttag
     2821 agatttggtc caagacagtc aaatcgacat tgtattagaa gcaaatattc agcaagctat
     2881 ttggtataaa ttgttagtta acttgggcat taattctatc acagcactcg gtagacagac
     2941 agttgcaatc atgcataatc ctgaaatacg tacactgtgt agacagctat tactagatgg
     3001 ttgtcgtgtt gcacaggcag aggggttaaa cttttcagaa caaactgtcg atactattat
     3061 gactatatat caaggttatc ccgacgaaat gggaacgagc atgtattacg acattgtgca
     3121 tcagcaacct cttgaagtcg aagcgattca aggctttatt tatcgacgtg cacgtgaaca
     3181 caatcttgac accccatatc ttgatactat ttatagcttt ttacgcgcgt atcaacaaaa
     3241 tatgtaacca catatataat ataaaaagac cttaacgatg catttagaac cacctgttcc
     3301 taatatcgct aaggtctttt aattatatta gactattcag cttctctaat ttcttctgcc
     3361 acatctttat agtctatttt cgctttaaca aacgtctcgt tatttaccgg gaaatgttgt
     3421 tggaatgttt caaagttttg tatctcaacg acaacgtcat ccacttcaaa gtcaagaaca
     3481 tgtccaccat aagctctttc atcatccgca aaatgtatat gaaaaccagc agaccctacg
     3541 ccatgaaata attctggtgt aaaaaatcca acaatggcac cacgaatatc ttgtcttttt
     3601 tcctcaggtt gtctgcgtgc tgaatcaatc aaacgtgtat atggcggttg ctgagcaggc
     3661 atcattcgta catgcatatg tttaaatgtg ccataaattt taacagccga aaataaattc
     3721 tcacttaaca tttcattttt aatttgtgcg aatacatcat cttgtgataa ttgttgcaat
     3781 ggaaatgtct tactcgcttt aaaattagta atcgatgcat agggtacttt ctcatcgcct
     3841 tttaattcta taaattcttt atgctcgtta gcatgatatg ccttcccgtc taaaaatatt
     3901 acttcgccat cagaccctgt taacgttgca atccctaaat tcccatgttc taacaattca
     3961 ttaattgtag ctgttccttc tagtaagcca gccattaacg tacctaatgt accatgttga
     4021 tacaagacat tcgtcattcc aaaaccatct ccctatagtt attcctcgtt gtcatgctct
     4081 acttcgtgat taatgcagaa ctactttcct ttatactcaa tgacgtctcg gcatttcgat
     4141 tcatgtcact aaattttcac gagtcataat actttattca attattattt tacgcaaaag
     4201 tattgcctct atcaatgctt gctaaatcaa aaccacccgt gtgaacgggt ggtttgttct
     4261 gcggctataa gccttcctta ctggccagcc ctaaaagggc actgacaagt cagccaactg
     4321 cactactatt ccagcaaccc taaagggtta ctctttttt
//
LOCUS       DAPSKH010000102         4311 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPSKH010000102 DAPSKH010000000
VERSION     DAPSKH010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4311
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.104"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..853
                     /locus_tag="RPH49_002561"
     CDS             <1..853
                     /locus_tag="RPH49_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-processing protein DprA"
                     /protein_id="HDY5125671.1"
                     /translation="VENIRTELFFLKQFGFNNTLLQEIFIKGLDPIKTIFSNEYLIRA
                     NIGRKFTDKDVLLANDYYKYREFKYYLFNKDEFFRDSKSKIYFKFDETNITKLLPEKI
                     MPLFMYTKGNNSLLDIKKQRVAIIGTRHPSNRAIKITKKITQKFLEDNYVIVSGLAEG
                     IDTISHKTAIKYNGNTIAILPTNFKNIYPKENIELAKEILDKGLLLTSIGPNENTYKS
                     SFLDRNKYIANISDIVVVTETNLKSGTMNTIRSASIAGKKILFVNQGDNLINNKIYEF
                     GGEMIDD"
     gene            846..2027
                     /locus_tag="RPH49_002562"
     CDS             846..2027
                     /locus_tag="RPH49_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosyl transferase"
                     /protein_id="HDY5125672.1"
                     /translation="MTKKNKSILISKLLFFTENNKLIEENLRIADLFYEHDIALGILA
                     RSTTINILRSKIPTDYQEKINFLSRDDKNKKDYIKQNKDLIIAVIGVVNEDAIYSFNC
                     RLPLFNPEKLISKELDISEKVKQYGLPINKFENVIDCLKAYEIHQENYFNIPFNQKFS
                     VISLNNANTYQSPKDEERIKNIFSANLKGSVSERDQEILLILLFHLINEVRTNSYYDS
                     VKYWGTFPSSDPENKNTSISFLKECVRKILNGLPKKGSELLIRQKEMQSKHTTRSTER
                     INIKSNKDFETLIVNPELVNKIEGEVVCIIDDYITNGYSAEAAKHLLLAAGAKEVIFL
                     AFGKFGTKYYSTNYKIKGDVSSNYTYEFESELLCERVYEGKQVYNNGNNSEISRFNEL
                     I"
     gene            complement(2342..2641)
                     /locus_tag="RPH49_002563"
     CDS             complement(2342..2641)
                     /locus_tag="RPH49_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WXG100 family type VII secretion target"
                     /protein_id="HDY5125673.1"
                     /translation="MSSKDAKKSQEEARLQQLKQEMRNSTDNMVSNAKNNVALKSQTL
                     NEIIETINNSSQNLEGTFEGKASEAAQQSINKLKSNNENLKQKFETLLNTMKING"
     gene            complement(2656..4269)
                     /locus_tag="RPH49_002564"
     CDS             complement(2656..4269)
                     /locus_tag="RPH49_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipase"
                     /protein_id="HDY5125674.1"
                     /translation="MLLRDSDARMLSENSYDKLSVDEVYTFSNKKQYKVIEKRDDTQN
                     GFRAYVFAPVIKGKVDKSQLLIGYAGTDPYSLNDIRTDLQLPIHHNTNNLKINNHYKD
                     LKNSTIHKKYNTIKDKNDLFSFSSNLNSKALFGDLWAAKFAPTQMDESDAFTESVKKK
                     YPDSEIHPLGHSLGAFLAQYNLIKHNLDNGTTFAAPNVYHSFTGDFKKDIDNGVYDSK
                     IRNIGHFDDPINNFNFFDHPIGENIIVMPHYDGFITALPLIGQHTIESYNDFDADGTV
                     KEMPELEQFNHDPFLNNRFQLFDPFGINSRFFDSFKIDSSILNRPSENDFDPFAILNK
                     KDKLFESNDLDIEGFNNKPKEDLSIDLNPFDDELNDEDEPLIPKRGDSKKLKAEKKIS
                     VKKGNGGSKNTGKKVKIQPDEVRNIANTIRDRIFLYSQIITALDEYREETISGANRIL
                     DKYQSDLLSGSHEFTTPYDHEQYMEILSVEGSFGNFKFYNSGLMDDLIQELDQNKKDL
                     LQFAEKLEFAANKFEEKDLEESDVFGLFS"
BASE COUNT         1561 a          564 c          635 g         1551 t
ORIGIN      
        1 ggttgaaaac ataagaactg aattattttt tttaaagcag ttcggtttta ataataccct
       61 tttacaagaa atttttataa agggactaga tcctataaaa actattttca gtaatgaata
      121 tctaatacgt gctaatatag gtcgtaaatt tactgataaa gatgtattgt tagccaatga
      181 ttactataaa tatagagaat tcaaatatta tttatttaac aaggatgaat ttttcagaga
      241 tagtaaaagt aaaatatatt ttaaatttga tgaaactaac ataactaagc tattaccaga
      301 aaaaataatg cctctcttta tgtatacaaa agggaataat tcacttttag atattaaaaa
      361 acaaagggta gctataatag gtactcgtca tccttcaaat agagcaataa aaataacgaa
      421 aaaaataact caaaaattct tggaagataa ctatgtaatt gttagtggtt tagcagaagg
      481 tattgatact atatcccata aaactgctat taaatataat ggtaatacaa ttgcaatatt
      541 accaacaaat ttcaaaaata tttatcctaa agaaaatata gagttagcaa aagaaatatt
      601 ggacaaagga ttattgctca catctattgg accaaatgaa aatacttata aatctagttt
      661 tttagataga aataaatata tagcaaatat tagcgatata gtggtagtaa ctgaaacgaa
      721 tttaaaaagt ggaactatga atacaatcag aagtgcgagt atagcaggga aaaagatctt
      781 gttcgtaaat caaggagata atctaattaa taacaaaatt tatgaatttg gtggggaaat
      841 gatagatgac taaaaaaaac aaaagcattt taatatcaaa gttattattt tttacagaaa
      901 acaataaatt aattgaagaa aatttaagaa ttgcagatct gttttatgaa catgatatag
      961 cattggggat tttagctcga tctacaacaa taaatatatt acgctccaaa attccaacag
     1021 attatcaaga gaaaataaat tttttgagta gagatgataa aaataaaaaa gattacataa
     1081 agcaaaacaa agatttaatt attgctgtaa taggagtagt taatgaagat gctatatact
     1141 cttttaactg tagattaccg ttatttaatc cagaaaaatt aattagtaaa gaattggata
     1201 tatctgaaaa agtaaaacaa tatggtttgc ctatcaataa gttcgaaaat gttattgatt
     1261 gtttaaaggc atatgaaatt catcaagaaa attattttaa tataccattt aatcaaaaat
     1321 ttagtgtaat aagtttgaat aatgcaaata catatcaaag tccgaaggat gaagaaagga
     1381 taaagaatat tttttctgca aatttaaaag gtagcgtatc tgagagggat caagaaattt
     1441 tattaatttt actttttcat ttgattaacg aggtaagaac aaatagttat tatgatagtg
     1501 ttaagtattg gggtacattt ccttcttctg atcccgaaaa taaaaataca tctatttcat
     1561 ttttaaagga atgcgttagg aaaattctta atggtttgcc aaaaaaggga tcagaattgc
     1621 taatcagaca aaaagaaatg caatcaaaac atactactag aagtacagaa cgtattaata
     1681 ttaaaagcaa caaagatttt gaaactctaa tagtgaatcc agaactagtt aataaaattg
     1741 aaggagaggt agtttgtatt atagatgatt acataactaa tgggtattca gcggaggcag
     1801 ctaaacattt gcttttagca gcaggagcta aagaagttat ttttcttgca tttggtaaat
     1861 tcggaacgaa atattactcc acaaattata aaataaaagg tgatgtatca agtaattata
     1921 catatgaatt tgaaagtgaa ttactttgcg aaagggttta tgaaggaaag caagtttata
     1981 acaatggtaa taattctgaa atatcacgct ttaatgaatt aatttaaatg aacttagtca
     2041 cttattagtg cagtgtatct tcttagtatt tataaaatgt cagttaatcc catttaatat
     2101 attatgggtg ctcgtttata cttgtgatgt attgcgtgtt gaaatatata gcatctatag
     2161 atatcgtaat taagtataat tttcacagaa gtagaaatta aagaacaatt tatatttacg
     2221 tattaagaat taggaatgac ctacttgccg tcatgaaaat taaaatccct tcactatttg
     2281 tttagcgagg ggattttcgt aatgtataaa aaaatacaga taaattaata atttctcaat
     2341 attatccatt tatcttcatt gtatttaata gggtctcaaa tttttgttta agattttcat
     2401 tattgctttt gagtttattt atactttgtt gggctgcttc gcttgctttt ccttcaaatg
     2461 taccttctaa attttgcgaa gaattattaa ttgtttcaat gatttcattc aatgtttgag
     2521 attttaatgc tacattattt ttagcattgc taaccatatt atcagtacta ttacgcattt
     2581 cttgctttaa ttgttgtaat ctagcttctt cttgactttt ctttgcatct tttgagctca
     2641 tataaattac cctctttaac taaatagtcc aaaaacatcg ctttcttcta agtctttttc
     2701 ttcgaattta tttgcagcaa attctagttt ttcagcaaat tgtagcaagt cttttttgtt
     2761 ttgatctaat tcctgaatta agtcatccat taaaccacta ttataaaact tgaaatttcc
     2821 aaaacttccc tcaactgata aaatctccat atactgttca tgatcataag gtgttgtaaa
     2881 ttcatgtgaa ccgcttagaa ggtccgattg atatttatct aaaatgcgat tagcccctga
     2941 tattgtttct tctctatatt catccaatgc agtaattatt tgactataca aaaatattct
     3001 atcacgaatt gtgttggcga tatttcgcac ctcatcaggc tggattttta ctttcttacc
     3061 tgtatttttg gaaccaccat tacctttttt aacagagatt ttcttttctg cttttaattt
     3121 tttactatct cctcttttgg gaattaatgg ttcgtcctca tcatttaatt catcatcaaa
     3181 aggatttaaa tcaatgctta aatcttcttt tggtttatta ttaaatcctt ctatatcaag
     3241 gtcatttgat tcgaataatt tatctttttt attgagaata gcaaaaggat caaaatcatt
     3301 ttcacttggt ctatttaata tagaactatc gattttgaaa gagtcgaaaa atctgctatt
     3361 tataccaaat gggtcaaata actgaaatct attattaaga aatgggtcat gattaaattg
     3421 ttcaagttct ggcatttcct tcactgtacc atccgcatcg aaatcattgt atgattcaat
     3481 tgtgtgttga ccaattaaag gaagagcagt tataaatcca tcataatgtg gcattacaat
     3541 tatattttca ccaattggat gatcgaagaa gttaaagtta ttaataggat catcaaaatg
     3601 gccaatattg cgtatttttg aatcatatac accattatca atgtcttttt taaagtcgcc
     3661 agtaaatgaa tggtatacgt taggtgctgc aaacgttgta ccgttatcca gattatgttt
     3721 tattaaatta tattgagcta aaaacgcacc taaactatgt cctaatgggt gaatttcact
     3781 atctggatat ttctttttaa ctgattcagt aaaagcatca ctttcgtcca tttgagtcgg
     3841 tgcaaactta gctgcccata gatcaccgaa aagtgcttta ctatttaaat tagaagaaaa
     3901 actaaaaagg tcatttttat cttttattgt attgtatttt ttgtgaatag ttgagttttt
     3961 taaatcttta taatgattat taatttttag attatttgtg ttatgatgaa tgggaagttg
     4021 taaatcagta cgaatatcat ttagactata tgggtcagtg ccagcgtaac ctattaaaag
     4081 ttgactctta tcaactttac ctttgattac tggagcgaaa acatatgctc taaacccatt
     4141 ctgggtgtcg tcgcgttttt cgatgacttt gtattgtttt ttatttgaaa atgtatatac
     4201 ctcatcaact gataacttat catatgaatt ttcggataac attcttgcat cgctatctct
     4261 taataacatg tggaacactc cttataaaaa ataaaaaaga ggtaataata a
//
LOCUS       DAPSKH010000103         4233 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPSKH010000103 DAPSKH010000000
VERSION     DAPSKH010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4233
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.106"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            44..493
                     /locus_tag="RPH49_002565"
     CDS             44..493
                     /locus_tag="RPH49_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis-inhibiting protein CHIPS"
                     /protein_id="HDY5125675.1"
                     /translation="MKKKLATTVLALSFLTAGISTHHHSAKAFTFEPFPTNEEIESNK
                     KLLEKEKAYKESFKNSGLPTTLGKLDERLRNYLKKGTKNSAQFEKMVILTENKGYYTV
                     YLNTPLAEDRKNVELLGKMYKTYFFKKGESKSSYVINGPGKTNEYAY"
     gene            complement(586..920)
                     /locus_tag="RPH49_002566"
                     /pseudo
     CDS             complement(586..920)
                     /locus_tag="RPH49_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500032.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
     gene            complement(1571..2062)
                     /gene="sak"
                     /locus_tag="RPH49_002567"
     CDS             complement(1571..2062)
                     /gene="sak"
                     /locus_tag="RPH49_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylokinase"
                     /protein_id="HDY5125676.1"
                     /translation="MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASY
                     FEPTGPYLMVNVTGVDGKGNELLSPRYVEFPIKPGTTLTKEKIEYYVEWALDATAYKE
                     FRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVI
                     EKK"
     gene            complement(2253..3008)
                     /locus_tag="RPH49_002568"
     CDS             complement(2253..3008)
                     /locus_tag="RPH49_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5125677.1"
                     /translation="MKTYSEARARLRWYQGRYIDFDGWYGYQCADLAVDYIYWLLEIR
                     MWGNAKDAINNDFKNMATVYENTPSFVPQIGDVAVFTKGIYKQYGHIGLVFNGGNTNQ
                     FLILEQNYDGNANTPAKLRWDNYYGCTHFIRPKYKSEGLMNKITNKVKPPAQKAVGKS
                     ASKITVGSKAPYNLKWSKGAYFNAKIDGLGATSATRYGDNRTNYRFDVGQAVYAPGTL
                     IYVFEIIDGWCRIYWNNHNEWIWHERLIVKEVF"
     gene            complement(3020..3274)
                     /locus_tag="RPH49_002569"
     CDS             complement(3020..3274)
                     /locus_tag="RPH49_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDY5125678.1"
                     /translation="MINWKIRMKQKSFWVAILSAIFLFAQNIAKAIGYDIQVYTEQLT
                     DGLNAILGFLVLTGVIQDPTTKGIGDSHQALEYEEPRRKY"
     gene            3326..3433
                     /locus_tag="RPH49_002570"
     CDS             3326..3433
                     /locus_tag="RPH49_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125679.1"
                     /translation="MIFILWCVNLYIEKGQHAQTCYPSEPVKKTVAILD"
     gene            complement(3486..3662)
                     /locus_tag="RPH49_002571"
     CDS             complement(3486..3662)
                     /locus_tag="RPH49_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HDY5125680.1"
                     /translation="MDRWWLSEYKEVVPMLALLKSLERRRLMITISTMLQFGLFLIAL
                     IGLVIKLIELSNKK"
     gene            complement(3814..4110)
                     /locus_tag="RPH49_002572"
     CDS             complement(3814..4110)
                     /locus_tag="RPH49_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2951 domain-containing protein"
                     /protein_id="HDY5125681.1"
                     /translation="MGWFKKHEHEWRIRRLEENDKTMLSTLNEIKLGQKTQEQVNIKL
                     DKTLDAIQKEREIDEKNKKENDKNIRDMKMWVLGLVGTIFGSLIIALLRMLMGI"
BASE COUNT         1424 a          788 c          575 g         1446 t
ORIGIN      
        1 actataaatt taaatataga atttaaggag aattaacatc attatgaaaa agaaattagc
       61 aacaacagtt ttagcattaa gttttttaac ggcaggaatc agtacacacc atcattcagc
      121 gaaagctttt acttttgaac cgtttcctac aaatgaagaa atagaatcaa ataagaaatt
      181 gttagagaaa gaaaaagctt ataaagaatc atttaaaaat agtggtcttc ctacaacact
      241 aggaaaatta gatgaacgtt tgagaaatta tttaaagaaa ggcacaaaaa attctgctca
      301 atttgaaaaa atggttattt taactgaaaa taaaggttac tatacagtat atctgaatac
      361 accacttgct gaagatagaa aaaatgttga gttactaggt aaaatgtata aaacatactt
      421 ctttaaaaaa ggagagtcta aatcatctta tgtaattaat ggtcctggta aaactaatga
      481 atatgcatac taatagtagt tacataaatt aaaaggtagc tatttctttt ttatataaag
      541 gtttggcaga catttcataa cttgccaaac ctttatatat aattatcaaa ctgcgctaaa
      601 attaccaaaa ctgcttattc tattacctgt cttgtctacc tctcctgtcg ctatataacg
      661 acgttgtcca ctattagcaa tataagtaat ccatcttagc cattaatgca atatgcgccg
      721 tcatatttga tcgttgcgtt attgggtaat acacctgtaa ttcttgaatt agttgaatag
      781 ccatccctca cgttattacc tttaacatta gcaactgtgt aataaccagt ctctttttta
      841 tacggtacat tgtttttatc gagtgtataa cctgctggca ctggtgaatt cttttcattt
      901 ttagctggtg ttttaacatt actgatacct gatacacact tccaataaaa ataaccacac
      961 catttaagat gcggtgtagc gactgtaata tttctatgtt gttgagatat atgtatcgag
     1021 tgaagggcaa aaaggatatc aattgcagga taagtgttag gttactaggc cacttaacag
     1081 gctatatagt tcactcctac tatatacagt taattataac ataaaaagca ccccgtaaac
     1141 tattatacgg gaatgctaaa gtcatatata ctacggggga gtagtatgaa aactatgctc
     1201 tctatcataa gaaaaaaaca cccagtgaca tgcttgggtg aacaaggata gatgtaaata
     1261 gttgatgcat gtgtaacaca tcatagcaaa aaactagccc gaaagctagc tataacatac
     1321 aatctaaaaa gacgtccttt gaatacgtct agaaagatta taacataaaa aaataggcaa
     1381 gtaccgaagt acctgcctaa aaaaggatta tccacttttt catcctaact gatttctccc
     1441 cataagtcac ctaatatctg attaggtggg gaagaaccat tcgtgcatga atgagaattt
     1501 gatgaaagat aattttcact acacatattc aatcaagaca ttgctttcta taataaacaa
     1561 ctattttgtt ttatttcttt tctataacaa cctttgtaat taagttgaat ccagggtttt
     1621 taatatgctc tgataaatct gggacaacaa aacctttttc tgttataggg aaagacttcg
     1681 tttcttcttt tttcttattc ttatcataat aagtgacttc gatctttgcg cttggatcta
     1741 attcaactac tctaaactct ttatatgctg tcgcatctaa tgcccattcg acatagtatt
     1801 caattttttc ttttgtaagt gtagtcccag gtttaatagg aaactcgaca taacgagggg
     1861 atagcaattc atttccttta ccatcaactc cagtcacatt taccatcaaa tacgggcctg
     1921 ttggttcaaa ataactcgcg tcatcgcctt ttttatattt tcctttgtcg aatgaacttg
     1981 atgcacttac ctcattagta attgaagaaa atgagaataa taacaataaa acagttaaaa
     2041 ataataaact tcttttgagc atggcgcttc ctccaaatat aatatatttg tttttattta
     2101 tctcttttta tagctaacac ccttatttaa gatgataaat atcaacaact tcattttata
     2161 ttgagaaaat attaaaaatc aataaaatat taaaagaaac taaacttaca ttaaaaaata
     2221 attaacaaat atttaacatt ttaacctaag aattaaaaca cttctttcac aatcaatctc
     2281 tcatgccata tccactcatt atgattgttc caataaatgc gacaccaacc atctataatt
     2341 tcaaacacat atattaatgt tccaggcgcg tatacagcct gtccaacatc gaatctatag
     2401 ttagtacgat tatcaccgta tctagtggct gaagtagcac ctaagccgtc gattttcgca
     2461 ttaaaataag caccttttga ccatttaagg ttataaggcg ctttacttcc aactgttatt
     2521 ttacttgcag atttaccgac tgctttttga gcaggtggtt taactttatt tgtgatctta
     2581 ttcattaagc cctcactttt atacttaggt ctaataaagt gagtacagcc gtaataatta
     2641 tcccaacgta actttgcagg cgtatttgcg ttaccgtcat agttctgttc caaaattaaa
     2701 aattgatttg tattaccacc attaaacact aaaccaatat gaccgtattg tttatatatt
     2761 cctttggtaa atacagccac atcacctatt tgtggaacaa acgatggtgt gttttcatat
     2821 actgttgcca tgtttttaaa atcgttattg attgcatctt ttgcatttcc ccacattcta
     2881 atttctaaca accaataaat gtaatcaact gctaaatctg cacattggta accataccaa
     2941 ccgtcaaaat caatatatct accttgatac caacgtaacc ttgctcttgc ttcactgtat
     3001 gttttcatta ttttacctcc tagtattttc ttcttggttc ttcatattct aaagcttggt
     3061 ggctatcacc tataccttta gtagtcgggt cttgaatcac accagttaat actaaaaatc
     3121 ctaatatagc gtttaaaccg tctgttaatt gctctgtata aacttgaata tcatacccaa
     3181 tagctttggc gatgttttga gcaaataaaa agatagctga caatatcgct acccaaaatg
     3241 atttttgttt cattctaatt ttccaattaa tcatattctt atctcctttt atccaaaata
     3301 aaaagacgac taataagccg tctatttgat atttatatta tggtgtgtta atttatatat
     3361 agaaaaaggg caacatgcgc aaacatgtta ccctagtgag cccgttaaaa agacggtggc
     3421 tattttagat taaagattaa attaataacc atttaaccat cgaaaccagc caaagttagc
     3481 gatggttatt ttttattgct taattcaata agcttgatta ctagacctat caatgcaata
     3541 aggaataaac caaactgcaa catggtacta attgtaatca ttaggcgtct cctttctaaa
     3601 gatttcagta atgccaacat aggcaccacc tccttatact cagatagcca ccatctatcc
     3661 aacttgctca cttctgcata ttaccataat tacaacaata aataaaaagc cagtgccgat
     3721 gcactgacca aaaacattat ttacatttac cgaaccaaaa acatgtccag aaactataac
     3781 caaagattag tttaaacatt ttattcacct ctcttatatg cccataagca tacgcaataa
     3841 tgctataatt agcgacccaa atattgtccc aactaaacca agcacccaca ttttcatatc
     3901 acgtatgttc ttatcatttt ctttcttatt cttttcatct atttctcttt ctttttgaat
     3961 agcatctaag gttttatcta atttaatgtt aacttgctct tgggtttttt gacctaattt
     4021 aatttcgttg agtgtgctga gcattgtttt atcattctct tctaaccttc tgatgcgcca
     4081 ttcatgttcg tgttttttga accaccccaa ttcagtacac ccgctttcta aaagaataaa
     4141 gattatgagt atctaactca tagcttttca tactgtttca gtgttaactg ttacctctgg
     4201 agataaatct gatctttcaa ctacttcttt aac
//
LOCUS       DAPSKH010000104         4189 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPSKH010000104 DAPSKH010000000
VERSION     DAPSKH010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4189)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4189)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4189
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.107"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(294..1940)
                     /locus_tag="RPH49_002573"
     CDS             complement(294..1940)
                     /locus_tag="RPH49_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HDY5125682.1"
                     /translation="MNSSSPENPNGKKYSPVFIYSAIVVAIVVLLGAFLPEQFNYVTN
                     NIKMWITEKLGWYYLILTTIIVFFCIFLIFSPIGKLKLGKPNDKPEFNTISWFAMLFS
                     AGMGIGLVFYGAAEPMAHFATPPTADPKTTEAYTEALRSTFFHWGFHAWAVYGVVALA
                     LAYSQFRKGEPGLLSRTLRPLLGDKVEGPIGIFIDVLSVFATIVGVAVSLGMGALQIN
                     GGLHYLFNVPNNTFVQAIIIIVVTILFIASAWSGLSKGIQYLSNLNIGLGTILMVAAL
                     IVGPTVLILNMLTSSTGSLLNTFLFNSFDTAALNPQKREWMSSWTLYYWGWWLSWSPF
                     VGVFIARVSKGRSIREFISGVLLVPAIVSFVWFSVFGVLGIETGKKHKEIFDMTPETQ
                     LFGVFNHVPFGIVLSLIALLLIASFFITSADSATFVLGMQTTFGSLNPSSMVKVVWGI
                     SQALIAFVLLLAGGGNGAEALNAIQSAAIISAFPFSFVVILMMVSFYKDANQERKFLG
                     LTLTPNKHRLQEYIKSQQEDYESDILEKRQSRRNIEKKDN"
     gene            2144..2506
                     /gene="mscL"
                     /locus_tag="RPH49_002574"
     CDS             2144..2506
                     /gene="mscL"
                     /locus_tag="RPH49_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008530241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDY5125683.1"
                     /translation="MLKEFKEFALKGNVLDLAIAVVMGAAFNKIISSLVENIIMPLIG
                     KIFGSVDFAKEWSFWGIKYGLFIQSVIDFIIIAFALFIFVKIANTLMKKEEAEEEAVV
                     EENVVLLTEIRDLLREKK"
     gene            complement(2577..3446)
                     /locus_tag="RPH49_002575"
     CDS             complement(2577..3446)
                     /locus_tag="RPH49_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDY5125684.1"
                     /translation="MEMSRLNLTDDNDIDEIIAWRGEQEELEQKRDTYKKRYHEFEME
                     IARLESLTKDKELLDSDKLKDEYELKKGKMNTLIDEYSAVHYQCQNNINKTQSIVSHI
                     NYLNQELKDQQEIFQLAEIVSGKNNKNLTLENFVLIYYLDQIIAQANLRLATMSDNRY
                     QLIRREAVSHGLSGLEIDVFDLHSNKSRHISSLSGGETFQSSLALALGLSEIVQQQSG
                     GISLESIFIDEGFGTLDQETLETALDTLLNLKSTGRMVGIISHVSELKNRIPLVLEVK
                     SDQYQSSTRFKRN"
BASE COUNT         1391 a          731 c          586 g         1481 t
ORIGIN      
        1 atagaatatt gatttatgtc ccagcctgag ttaatttttt ataaaagtat agttaatttg
       61 cgtttatacc gtcaaacttc actttagctt tgtcaaaccc ctttctatta agttgtcaga
      121 aataaaccta tcttaaaata taaaaaaatc gagaattcgt agtttaataa cgaaattctc
      181 gttcttatcc ttttgaatat actcaatttt ccacaaaaac aaacaagtag tatatctgtt
      241 ctagctacta gaatgacata ctacttgtta tttaaatact taactaaatt ttattagtta
      301 tcttttttct ctatatttct acgtgactga cgcttttcaa gaatgtcaga ttcataatct
      361 tcttgttgac tcttgatata ttcttgtaag cgatgtttat tcggagtcaa tgttaaacct
      421 aggaatttac gttcctggtt cgcatccttg tagaaactta ccatcatgag tatgacgaca
      481 aaggagaatg ggaatgcact tataattgca gcactttgaa tcgcatttaa agcttcagcg
      541 ccgttaccgc caccagctaa taaaagtaca aatgctatta aggcctgtga aattccccaa
      601 acaactttta ccatactaga tggatttaat gaaccaaatg ttgtttgcat tcctaataca
      661 aatgttgctg agtcagcaga tgtaataaag aatgatgcaa ttaataataa tgcaatcaac
      721 gataaaacaa tgccaaatgg cacatgatta aacactccaa atagctgtgt ttcaggagtc
      781 atatcaaaaa tttctttgtg tttcttacct gtctcgatgc ctaatacacc aaagacacta
      841 aaccaaacaa aactaacaat tgctggaact agcaagacac cagaaatgaa ctctctaatt
      901 gaacgtcctt ttgaaactcg tgcaataaac actccaacga atgggctcca acttaaccac
      961 caaccccagt aataaagtgt ccatgaagac atccattcac gtttttgagg atttaaagct
     1021 gctgtatcaa aactattaaa caagaatgtg tttagtaaac tacccgtaga gctagttaac
     1081 atatttaaaa taagaacagt tggtccaaca attaaagcag ctaccattaa aatagtacct
     1141 aaaccaatgt tcaagttact taagtattga atacctttac ttaatccaga ccatgcactt
     1201 gctataaata agatagtaac aacaatgatg ataatcgctt gtacaaacgt attgtttgga
     1261 acattgaaca agtaatgtaa accaccatta atttgtagag cacccatacc taacgaaacg
     1321 gctaccccaa cgattgtcgc aaatacagat aaaacgtcaa taaaaatccc aataggacct
     1381 tctactttat cacctaaaag aggacgtaaa gttctagata ataaacctgg ttcaccttta
     1441 cggaattgcg aatatgccaa cgctaacgca acaacaccat aaacagccca agcatggaat
     1501 ccccaatgga aaaatgttga acgtagagct tcagtataag cttcagtagt tttgggatct
     1561 gctgtaggtg gcgtagcaaa gtgcgccatc ggttcagctg caccataaaa caccaaacct
     1621 atccccatac cagcactaaa caacatagca aaccatgaaa ttgtattaaa ctcaggtttg
     1681 tcatttggtt tacctagttt aagttttcca ataggactaa aaataaggaa tatacagaag
     1741 aaaacgataa tcgtagtaag aataagataa taccaaccta acttttctgt aatccacatt
     1801 ttaatattat tggtaacata gttgaattgt tcaggtaaaa atgcaccaag taatacgact
     1861 atagcaacaa caattgcact atagatgaag actggtgaat acttctttcc atttggattc
     1921 tctggtgaag aagaattcat aattaattac tcccttcaat tctatattta attttatgta
     1981 gtagaataaa aatattatct aaacatttta ttcaataact cacgcacctt tataggataa
     2041 caaaggtctt tgcgataatc aaattttctt gaataatcta ttttctaatt tttttatttg
     2101 ttgtataatt gaggttacat ttaaaaaaga gaggttgagt gtaatgttaa aagaattcaa
     2161 agagttcgcc ttaaaaggta acgtcttaga tttagcaatt gctgttgtga tgggtgcagc
     2221 tttcaacaag attatatctt cattagtaga aaatatcatt atgccattaa ttggtaaaat
     2281 tttcggatca gttgattttg ctaaagaatg gtcattctgg ggtattaaat acggtttatt
     2341 tatccaatct gttatcgact ttattatcat cgcgtttgct ttattcatct ttgttaagat
     2401 tgcaaataca ttaatgaaga aagaagaagc cgaagaagaa gcagttgtgg aagaaaatgt
     2461 tgtgttatta actgaaatca gagatttatt acgtgagaaa aaataatttt taaataaaaa
     2521 gagatgggct aaggttgttc tatacattcc aaagtaccat ctctattttt tatgttttaa
     2581 tttcttttga atcttgttga actctgatat tgatctgatt tcacttctaa aactaaaggt
     2641 attctatttt tcaattcgct cacatgtgaa ataatcccaa ccattctacc agttgattta
     2701 agatttaata aagtgtctaa cgctgtttca agcgtttctt gatctaatgt accgaatcct
     2761 tcatcaataa atattgattc tagtgaaata cctcctgatt gctgctgtac aatttcgctt
     2821 aaccctaaag ctaatgcaag cgacgattgg aaagtttctc cacctgataa cgagctaata
     2881 tgtctagact tatttgaatg caaatcaaat acatcaattt ctaggccact aagaccatga
     2941 gaaaccgctt ctcgcctaat tagttggtat cgattatctg acattgttgc taatctcaga
     3001 tttgcttgag caataatttg atctaaatag taaattaaga caaagttttc caatgtaaga
     3061 tttttgttat tcttaccact gacaatttca gccaattgaa atatttcttg ttgatccttt
     3121 aattcttgat ttaagtaatt aatatgcgaa actatagatt gtgttttatt aatattattt
     3181 tgacattgat aatgaacagc agagtattca tctatcagtg tattcatctt tccttttttt
     3241 agctcatatt catcttttaa tttatcagag tccaataact ctttatcctt agttaatgat
     3301 tctaacctag ctatttccat ttcaaattca tgataacgtt ttttataagt atcccttttc
     3361 tgctctaatt cctcttgctc gcccctccag gctattattt catctatatc attgtcatca
     3421 gttaaattca gcctcgacat ttccatttca atagactgtt cattcaattc taagtcatta
     3481 ttgtaagttt ctagttgatt ttcataatga tttagattat tttgctcaat tgactttctt
     3541 tgagacaatt gcattaactt atcttcaatc tcctttgaga gttcttgatg ctgattcaca
     3601 tcttgaacat acttcttata atccacctca aaattagtga tattattata tttcgagagt
     3661 gtttcaaatt cagtgatgag atctcgacat aatttcaact cagattcatt tttatttaga
     3721 cgcaattgtt tattatgaat ttgcaacgtt agattatctt tttcttcttt catttgttct
     3781 ataaatttat taagatctct ttgattattc aatgcatttt cattttctag cagacgctta
     3841 ttcaatactt caagtgaaaa atcactttgc gttttaatat taatattcga tattttttca
     3901 ttaacaaatt taatttcaga attatgcaca gcaatattcg attttatagc gtggatattt
     3961 gcttcaattt ctttaatttc attttgacgt ttagcaatac tgtcaaaatc aatatgatgc
     4021 cctaaatcct gaatttcatt accacatatc ggacattgat ctccaatatt tacagcagat
     4081 ttaatttcac ttataaagct ttctttatca tttaagtcca attttgtttt atcgtagcga
     4141 tctaatttta tttcgagatt cttcaatata gatgtttctt cattaattt
//
LOCUS       DAPSKH010000105         3984 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPSKH010000105 DAPSKH010000000
VERSION     DAPSKH010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3984
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.108"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            65..>3984
                     /gene="sdrD"
                     /locus_tag="RPH49_002576"
     CDS             65..>3984
                     /gene="sdrD"
                     /locus_tag="RPH49_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrD"
                     /protein_id="HDY5125685.1"
                     /translation="MLNRENKTAITRKGMVSNRLNKFSIRKYTVGTASILVGTTLIFG
                     LGNQEAKAAESTNKELNEATTSASDNQSSDKVDMQQLNQEDNTKNDNQKEMVSSQGNE
                     TTSNGNKLIEKESVQSTTGNKVEVSTAKSDEQASPKSTNEDLNTKQTISNQEALQPDL
                     QENKSVVNVQPTNEENKKVDAKTESTTLNVKSDAIKSNDETLVDNNSNSNNENNADII
                     LPKSTAPKRLNTRMRIAAVQPSSTEAKNVNDLITSNTTLTVVDADKNNKIVPAQDYLA
                     LKSQIKVDDKVKSGDYFTIKYSDTVQVYGLNPEDIKNIGDIKDPNNGETIATAKHDTA
                     NNLITYTFTDYVDRFNSVQMGINYSIYMDADTIPVSKNDVEFNVTIGNTTTKTTANIQ
                     YPDYVSRDNNSIGSAFTETVSHAGNAEDPGYYIQTVYVNPSEKTLTNAKLKVEAYHKD
                     YPDNVGQINKNVTKIKIYQAPKDYVLNKGYDVNTNQLIDVTEQFKDKITYGTNDSVNV
                     DFGSINNSYVVMVDTKFEFTTSESPTLVQMATLTSDGNRSVSTGNALGFTNNQSGGAG
                     QEVYKIGNYVWEDTNKNGIQELGEVGVKGVTVVAYDNKTNKEVGRTITDEKGGYLIPN
                     LPNGDYRVEFSNLPKGYEVTPSKQGNNEELDSNGLSSVITVNGKDNLSADLGIYKPKY
                     NLGDYVWEDTNKNGIQDQDEKGISGVTVTLKDENGNVLKTVTTDADGKYKFTDLGNGN
                     YKVEFTTPEGYTPTTVTSGSDIEKDSNGLTTTGVINGADNMTLDSGFYKTPKYNLGNY
                     VWEDTNKDGKQDSTEKGISGVTVTLKNENGEVLQTTKTDKDGKYQFTGLENGTYKVEF
                     ETPSGYTPTQVGSGTDEGIDSNGTSTTGVIKDKDNDTIDSGFYKPTYNLGDYVWEDTN
                     KNGVQDKDEKGISGVTVTLKDENDKVLKTVTTDENGKYQFTDLNNGTYKVEFETPSGY
                     TPTSVTSGNDTEKDSNGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQ
                     DSTEKGIKDVKVTLLNEKGEVIGTTTTDENGKYRFDNLDSGKYKVIFEKPAGLTQTGT
                     NTTEDDKDADGCEVDVTITDHDDFTLDNGYFEEDTSDSDSDSDSDSESDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDAGK"
BASE COUNT         1615 a          592 c          734 g         1043 t
ORIGIN      
        1 atatacattt ttgtatttaa aacaattgta ttatttaaaa atttgatgaa ttaggagtaa
       61 tctaatgcta aacagagaaa ataaaacggc aataacaaga aaaggcatgg tatccaatcg
      121 attaaataaa ttttcgatta gaaagtacac agtgggaaca gcatcaattt tagtaggtac
      181 aacattaatt tttggtctgg ggaaccaaga agcaaaggct gcagaaagta ctaataaaga
      241 attgaacgaa gcgacaactt cagcaagtga taatcaatcg agtgataaag ttgatatgca
      301 gcaactaaat caagaagaca atactaaaaa tgataatcaa aaagaaatgg tatcatctca
      361 aggtaatgaa acgacttcaa atgggaataa attaatagaa aaagaaagtg tacaatctac
      421 cactggaaat aaagttgaag tttcaactgc caaatcagat gagcaagctt caccaaaatc
      481 tacgaatgaa gatttaaaca ctaaacaaac tataagtaat caagaagcgt tacaacctga
      541 tttgcaagag aataaatcag tggtaaatgt tcaaccaact aatgaggaaa acaaaaaggt
      601 agatgccaaa actgaatcaa ctacattaaa tgttaaaagt gatgctatca agagtaatga
      661 tgaaactctt gttgataaca atagtaattc aaataatgaa aataatgcag atatcatttt
      721 gccaaaaagt acagcaccta aacgtttgaa tacaagaatg cgtatagcag cagtacagcc
      781 atcatcaaca gaggctaaaa atgttaatga tttaatcaca tcaaatacaa cattaactgt
      841 cgttgatgca gataaaaaca ataaaatcgt accagcacaa gattatctag cattaaaatc
      901 acaaattaaa gttgatgaca aagttaaatc aggtgattat ttcacaataa aatactcaga
      961 tacagtacaa gtatatggat tgaatccgga agatattaaa aatattggag atattaaaga
     1021 tccaaataat ggtgaaacaa ttgcgactgc aaaacatgat actgcaaata atttaattac
     1081 atatacattt acagattatg tagatagatt taattctgta caaatgggaa ttaattattc
     1141 aatttatatg gatgctgata caattcctgt tagtaaaaac gatgttgagt ttaatgttac
     1201 gataggtaat actacaacaa aaacaactgc taacattcaa tatccagatt atgtttctag
     1261 agataataat tctataggtt cagcatttac tgaaactgtt tcacatgcag gtaatgcaga
     1321 agacccgggt tactatatac agactgttta tgtaaatcca tcggaaaaaa ctttaacaaa
     1381 tgctaaatta aaagttgaag cttatcataa ggattatcct gacaatgtag gtcaaataaa
     1441 taaaaatgta actaaaatta aaatttatca agcaccaaaa gactatgttt taaacaaagg
     1501 ttatgatgtt aatacaaatc aacttataga tgtgactgaa caatttaaag ataagattac
     1561 atacggaact aatgacagtg taaatgttga ttttggtagc attaacaatt cttatgtagt
     1621 tatggtggat acaaaatttg aatttacaac tagtgaaagt ccaacacttg ttcaaatggc
     1681 aactttgact tctgatggaa acagatccgt ttctactggc aatgctttag gatttactaa
     1741 taaccaaagt ggtggtgctg gtcaagaagt ctataaaatt ggtaactacg tttgggaaga
     1801 tacaaataaa aatggtattc aagaattagg ggaagttgga gtaaaaggtg taacagtggt
     1861 tgcatatgac aataaaacta ataaagaagt tggaagaacg attactgatg aaaaaggagg
     1921 gtacttgatt ccaaacttac ctaatggaga ttaccgtgta gaattttcaa acttaccaaa
     1981 aggttatgaa gtaacccctt caaaacaagg taataacgaa gaattagatt caaacggctt
     2041 atcttcagtt attacagtta atggcaaaga taacttatct gcagacttag gtatttacaa
     2101 acctaaatac aacttaggtg actatgtatg ggaagataca aataaaaatg gtattcaaga
     2161 tcaagatgaa aaaggtatat ctggcgtaac ggtaacatta aaagatgaaa acggtaacgt
     2221 gttaaaaaca gttacaacag acgctgatgg caaatataaa tttactgatt taggtaatgg
     2281 taattataaa gttgaattta ctacaccaga aggctataca ccgactacag taacatctgg
     2341 tagcgacatt gaaaaagact ctaatggttt aacaacaaca ggtgttatta atggtgctga
     2401 taacatgaca ttagatagtg gattttacaa aacaccaaaa tataatttag gtaattatgt
     2461 atgggaagat acaaataaag atggtaagca ggattcaact gaaaaaggta tttcaggcgt
     2521 aacagttaca ttgaaaaatg aaaacggtga agttttacaa acaactaaaa cagataaaga
     2581 tggtaaatat caatttactg gattagaaaa tggaacttat aaagttgaat tcgaaacacc
     2641 atcaggttac acaccaacac aagtaggttc aggaactgat gaaggtatag attcaaatgg
     2701 tacatcaaca acaggtgtca ttaaagataa agataacgat actattgact ctggtttcta
     2761 caaaccgact tacaacttag gtgactatgt atgggaagat acaaataaaa acggtgttca
     2821 agataaagat gaaaagggta tttcaggtgt aacagttacg ttaaaagatg aaaacgacaa
     2881 agttttaaaa acagttacaa cagatgaaaa tggtaaatat caattcactg atttaaacaa
     2941 tggaacttat aaagttgaat tcgagacacc atcaggttat acaccaactt cagtaacttc
     3001 tggaaatgat actgaaaaag attctaatgg tttaacaaca acaggtgtca ttaaagatgc
     3061 agataacatg acattagaca gtggtttcta taaaacacca aaatatagtt taggtgatta
     3121 tgtttggtac gacagtaata aagacggcaa acaagattca actgaaaaag gtatcaaaga
     3181 tgttaaagtt actttattaa atgaaaaagg cgaagtaatt ggaacaacta caacagatga
     3241 aaatggtaaa tatcgtttcg ataatttaga tagcggtaaa tacaaagtta tttttgaaaa
     3301 gcctgctggc ttaacacaaa caggtacaaa tacaactgaa gatgataaag atgcagatgg
     3361 ttgcgaagtt gacgtaacaa ttacggatca tgatgatttc acacttgata acggatactt
     3421 cgaagaagat acatcagata gcgactcaga ttcagatagc gattcagaat cagatagcga
     3481 ctcagactca gacagcgact cagattcaga tagcgactca gattcagaca gcgactcaga
     3541 ttcagatagc gattcggact cagacagcga ttcagattcg gatagcgact cagactcaga
     3601 tagcgattca gattcagata gcgattcaga ctcagacagc gattcagatt cagacagcga
     3661 ctcagactca gatagcgact cagattcgga cagcgattca gactcagata gcgactcaga
     3721 ctcagatagc gactcagatt cagacagcga ttcagattca gacagtgatt cagattcaga
     3781 cagcgactca gattcagata gcgattcaga ctcagattca gatagcgatt cagactcaga
     3841 ctcagatagc gattcagatt cagacagcga ctcagattcg gacagcgact cagactcaga
     3901 cagtgattca gattcagata gcgactcaga ctcagatagc gactcagatt cagacagtga
     3961 ttcagactca gatgcaggta agca
//
LOCUS       DAPSKH010000106         3920 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPSKH010000106 DAPSKH010000000
VERSION     DAPSKH010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3920)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3920)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3920
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.109"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..721
                     /locus_tag="RPH49_002577"
     CDS             <1..721
                     /locus_tag="RPH49_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125686.1"
                     /translation="LIYFSFLDINGHFSFTNYQQIFTTKYLKMFAYSILYAALITIIT
                     LAISYPAAYYITRSKFQNILLMIMIIPTWINLLLKTYAFIGLLSHDGVINQFFHLFNL
                     PSFNLLFTTGAFLVVASYIYIPFMILPIFNSMKAIPNNLLQASSDLGASPFYTFRKVI
                     MPLTKEGVMTGIQVTFIPSLSLFMITRLIAGNKVINIGTAIEEQFLTIQNYGMGSTIA
                     IFLIVFMAFILIITKSSNGRG"
     gene            727..1536
                     /locus_tag="RPH49_002578"
     CDS             727..1536
                     /locus_tag="RPH49_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDY5125687.1"
                     /translation="MKWYGKLYIGILLAILYIPIFFLMFYSFNSAGNMIHFEHFTLEH
                     YQSLFQNDHLMSVIFNTIAVALLAASISTVIGTFGAIAIYYLRNKKFKVTLLTLNNVL
                     MVSSDVVIGASFLIMFTTIGHFTGLGLGFWTVLISHIAFCIPIVVIIVLPQLYEMNNN
                     MLNAARDLGATEPQLLSNIIIPNILPSIIGGFFMALTYSLDDFTVSFFVTGNGFSVLS
                     VEVYAMARKGISMEINAISTLLFAVIVLGILGYYLIQYVINKKKLIKRGVK"
     gene            1536..2609
                     /locus_tag="RPH49_002579"
     CDS             1536..2609
                     /locus_tag="RPH49_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="HDY5125688.1"
                     /translation="MKRFLQLIIGSLVVGMLCLTLSHWFKSKEQVHTNQKIYVYNWGE
                     YIDPELIKKFEKETGIQVVYETFDSNEAMEAKIRNGGTHYDVAFPSEYTVQKLKRDHL
                     LLPIDHNKVPNIKNLDSDYMNMSFDKGNKYSLPYFFGTVGILYNKEKYPNESFDSWKS
                     LYNPKFKNQILLVDGAREIIGMSLNKLGYNLNDRNSHHLKEAERDLTKLAPQVRGVVG
                     DEITMMLQQNEGNIAVVWSGVAAPLVQEGDKYNYVIPKEGSNLWFDNMVIPKTAQNKE
                     GAYKFMNFLLDAKNNKQNTEFVGYATPNKAARQLLPKEIKDDHRFYPTKKEQERLEVY
                     KDLGPEVLSEYNENFLNFKMSLK"
     gene            2683..3702
                     /locus_tag="RPH49_002580"
     CDS             2683..3702
                     /locus_tag="RPH49_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDY5125689.1"
                     /translation="MTGEQFTQIKRPVSRLTEKVLGWLCWVMLLVLTVITMFIALVSF
                     SNNTSIANLENTLNNNAFIQQLLAGNGYNTTQFVIWLQNGIWAIIVYFIVCLLISFLA
                     LISMNIRILSGFLFLISAIVTIPLVLLIVTLIIPILFFIIAMMLFIRKDKVEMVAPQY
                     YEEYNGPIYDYREPVYERPQPKDDYYDVPKYEKELDKSNTVYDQEQERDKYDQFPKRA
                     VESEYNHDEHTEEEPSVLSRQAKYKQKSTEELGIEDDGYYAEPEVDPKELKAQQKREK
                     AEIKAKKKEKRKAYNQRMKERRKNQPSAVSQRRMNFEERRQIYNNDISEERNSSEVKD
                     KKEQE"
BASE COUNT         1402 a          515 c          655 g         1348 t
ORIGIN      
        1 actcatttat ttttcatttt tagatatcaa tggacatttt agtttcacga attatcaaca
       61 aatttttact acaaaatatt taaaaatgtt tgcatattca attttatatg ccgctttaat
      121 aacaattatt acgttggcta taagttatcc agctgcctat tatattactc gttcgaaatt
      181 tcaaaatatc ttattaatga taatgattat tccaacatgg ataaatttat tgttaaagac
      241 atatgctttt ataggtttat taagtcatga tggcgtgatt aatcaatttt tccacttatt
      301 taatttacca tcattcaatt tgttatttac aactggtgcg tttttagtag tggcaagtta
      361 catttatata ccatttatga ttttacctat atttaatagc atgaaagcaa ttcctaataa
      421 tttattgcag gcctcaagtg atttaggtgc tagtcctttt tatactttta gaaaagtaat
      481 catgccgtta acaaaagaag gtgttatgac tgggattcaa gtaaccttta ttccatcact
      541 ttcattattt atgattacaa gattaattgc aggtaataaa gtcataaata taggtacggc
      601 aatagaggaa caatttttaa caattcaaaa ttatggtatg ggatcaacta tagctatatt
      661 cttaattgta tttatggcat tcattttaat cattacaaaa tcatctaatg ggagagggtg
      721 aatcatatga aatggtatgg aaagctgtat atcgggatac ttttagcgat tttatacatc
      781 ccaatattct ttttaatgtt ctattcattc aattcggctg gtaatatgat tcactttgaa
      841 cattttacat tagagcatta tcaatcatta tttcaaaatg atcatttaat gtcggtcatt
      901 tttaatacga tagctgtagc acttttagca gcctcaattt ctacagttat tggtacattt
      961 ggtgccattg ctatttatta tttaagaaat aaaaagttta aagtaacttt actaacattg
     1021 aataatgtct tgatggtatc atccgacgtt gtcataggtg catcattctt aattatgttt
     1081 acaacgattg gccattttac tggtcttggt ttaggatttt ggacagttct aatatctcat
     1141 attgcatttt gcatacctat agttgtgatt atcgtcttac cacaactgta tgaaatgaat
     1201 aataatatgt taaatgctgc aagagattta ggagcgactg aaccacaatt attaagcaac
     1261 attattattc ctaatatttt accttctatt ataggaggtt tctttatggc tttaacttat
     1321 tcactagacg atttcacagt aagtttcttc gttactggta atggctttag tgtgttatca
     1381 gttgaagttt atgctatggc gagaaaagga attagtatgg aaattaatgc gatttcaaca
     1441 ttattgtttg ctgttattgt attaggaata ctaggatatt atttgattca atacgtgatt
     1501 aataagaaaa aactaatcaa gcgaggtgta aaataatgaa acgtttttta caactcatta
     1561 taggttcatt agttgtgggt atgctttgtc ttactttaag tcattggttt aaatctaaag
     1621 aacaagtgca tacaaatcaa aaaatttacg tatacaattg gggcgaatat attgatccag
     1681 agttaattaa gaaatttgaa aaagaaactg gcattcaagt cgtttatgaa actttcgatt
     1741 caaatgaagc gatggaagcc aaaattcgta atggcggtac acattatgat gttgcttttc
     1801 ctagtgaata tacagttcaa aaattgaaaa gagatcattt attgttacca atagatcata
     1861 ataaggtacc taatattaaa aatttagatt cagattatat gaatatgtca tttgataaag
     1921 gcaataaata ttctttacct tatttctttg gaactgtagg tattttatat aataaagaaa
     1981 agtatccaaa tgaatcattt gatagttgga agtcattgta taatcctaaa tttaaaaacc
     2041 aaattttact agttgacggt gctagagaga ttataggcat gagtttgaat aaacttgggt
     2101 ataatcttaa tgaccgtaat tcgcaccatt taaaagaagc agagcgagat ttaaccaaac
     2161 tagcaccaca agtaagaggt gtcgtaggtg atgaaattac catgatgctt caacaaaatg
     2221 aaggtaacat agcggttgtt tggagtggtg ttgcagcacc tctagtgcaa gaaggggata
     2281 aatataatta tgttattcct aaagaaggat cgaatttatg gttcgacaat atggtaattc
     2341 caaaaacggc acaaaataaa gagggtgcat ataaatttat gaatttttta ttagatgcta
     2401 aaaataacaa gcaaaataca gaattcgtag gctatgcaac gccaaacaag gctgctcgac
     2461 aattgttgcc taaagagatt aaagacgacc atcgtttcta tccgactaag aaagagcaag
     2521 aacgccttga agtttataaa gatttaggac ctgaagtttt aagtgaatac aatgaaaact
     2581 ttttgaattt caaaatgtca ttaaaataaa atcataaata gtagttattt actgtatatt
     2641 tagttataat aacgggataa gtactataag gagttgtaac gaatgactgg agaacaattt
     2701 actcaaatta aacgtccagt aagtagatta actgaaaaag ttctaggttg gttatgttgg
     2761 gtgatgttat tagtgcttac tgtcattacg atgtttatag cacttgtttc attcagtaat
     2821 aacacatcga ttgctaatct tgaaaataca ttaaacaata atgcatttat ccagcaatta
     2881 ttagctggaa atggctataa tacaacacaa tttgtaatat ggttacaaaa tggtatatgg
     2941 gctattatcg tttactttat tgtttgtttg ttgatttcat ttttagctct catatctatg
     3001 aatataagaa tcttgtcagg tttcttattc ttaatatcag caattgtaac gattccttta
     3061 gttttactta tcgttacttt aatcattccg atattattct ttattattgc gatgatgcta
     3121 tttataagaa aagataaagt tgaaatggtt gcgccacaat attatgaaga gtataacgga
     3181 ccgatttatg attatcgtga acctgtgtat gagcgcccac aaccgaaaga tgattattat
     3241 gatgtgccta aatatgaaaa agaattggat aaatcaaata ctgtatatga tcaagaacag
     3301 gaaagagata aatatgatca atttcctaaa cgtgcagttg aaagtgaata taatcatgat
     3361 gagcacactg aggaagaacc atcagtatta tccagacagg ctaaatacaa acaaaaaagt
     3421 actgaagaac taggtattga agatgatggt tattatgcag aacctgaagt tgatccaaaa
     3481 gaattgaaag cacaacaaaa gcgagaaaaa gctgaaatta aagctaagaa aaaagaaaaa
     3541 cgtaaagctt ataaccaacg aatgaaagaa cgtaggaaaa atcaacctag cgcagttagt
     3601 caacgtcgaa tgaattttga agagcgacgt caaatttaca acaatgatat ttctgaagaa
     3661 cgcaattcaa gtgaagttaa ggacaaaaaa gagcaagaat aaatattgat gatacccaga
     3721 tttagtaagt agaggtcttt tgcttattaa tctgggtttt tatatgaggt taattatcga
     3781 taatgtctaa ttaaagtgtt taggtgtcaa aattttaaat gacgatttct cattaccata
     3841 cacctaaatt accatcaatc tgaattcaga tgtttattat aaaaattaga tgaaaaatat
     3901 gttaatatac aagtaaatta
//
LOCUS       DAPSKH010000107         3770 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPSKH010000107 DAPSKH010000000
VERSION     DAPSKH010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3770
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.111"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(1390..2697)
                     /locus_tag="RPH49_002581"
     CDS             complement(1390..2697)
                     /locus_tag="RPH49_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDY5125690.1"
                     /translation="MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFI
                     ASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNR
                     FLIMVTWNIDELGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTS
                     VSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLH
                     SKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIA
                     SINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISD
                     KHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYH
                     GITKIIIIFVMLCGKVGLLTLLRTFIPPKNPKNYRYTKGQIYL"
     gene            2858..3769
                     /locus_tag="RPH49_002582"
     CDS             2858..3769
                     /locus_tag="RPH49_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-hydroxamate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDY5125691.1"
                     /translation="MKRLIGILLCNLFILTACSASVDKTSNSTKTTDYKIENGETLKV
                     PEKPKRVAVLTGFYVGDFIKLGIKPIAVSDITKDSSILKPYLKGVDYIGENDVERVAK
                     AKPDLIVVDAMDKNIKKYQKIAPTIPYTYNKYNHKEILKEIGKLTNNEDKAKKWIEEW
                     DDKTRKDKKEIQSKIGQATASVFEPDEKQIYIYNSTWGRGLDIVHDAFGMPMTKQYKD
                     KLQEDKKGYASISKENISKYAGDYIFLSKPSYGKFDFEKTHTWQNIEAVKKGHVISYK
                     AEDYWFTDPITLEHLRSKLKKEILNKK"
BASE COUNT         1430 a          465 c          587 g         1288 t
ORIGIN      
        1 ctcctataat ttatttgtaa tcgattacaa agtaatttta caactattat ttatgtaaat
       61 ctattaaata attattaaca aatctataaa attttatggt taaaatataa tgattttgag
      121 ctagaaatat tcgtcattta tgctataatt attttagaca cagcaatgtg ttcaaatttt
      181 catctattcg taagttagcc ttcgggctga ctttttattt ccattattca catgttaata
      241 ttgttgttat ttagggaggt acttcggtac ttgcctattt ttttatgtta taatgtaatt
      301 acattaccag taagcaatcc ggcttaaaac cacatttccg gtagtcaatc cggctatgca
      361 gaggacttac ttgcgtaaag cagtaagaag ctgactgcat atttaaacca cccatactag
      421 ttgctgggtg gttatttttt tattcataaa cttctatttc aaaatgatta catgcgataa
      481 taaaaatttt ttcacacgtt gcaggcagtg aatacgtatt tgaatacgtt aattatgaag
      541 tgatgttggg tgcacaaatt tatattgttt tatcaatttt aacatttcac actaacttta
      601 ttaggtgata taagatgctg agagaagcat tatattgcaa tgaaaaatca ttatatggat
      661 aatcatatcg atcattgcaa atatacttat agagatttat gtgtgtaata attggtggtc
      721 ataaattggt cataatgaaa taaaaaaact aaaaaaattg aatgtataaa gaatacacga
      781 tgctgattta ataggatttt tgtatgtgat ttatatctat ttcatactgc ccttaatgcc
      841 gggaatgatg taaaactgta tatagttttg actaattaga aaattacatt atgaacgagt
      901 atgatgtatt ctaagtacaa attagaatgc acgcaaatat attttaatta cgagacgttt
      961 tccatttggt gactagactt atgggaggcg tcttttttat gtgctaattt gtaattgaga
     1021 ttcataatgg tatttaaatc attatggtgc gggagttatg gtattgccat aatatgagag
     1081 tgcatccact tctataagta atgcatattg cgagtgcagg aatgaatgag tgcttgatta
     1141 aaatccttat gggtggttga cataattaaa agaaaccaca tttaaaattt cttaatcaca
     1201 agcggttaac taggtatagt ttagttttga gtaaatcttt ttaaaggtgt acttgtgcat
     1261 tttacttaat taaagacata agacatttaa tgggcctaaa ataaatagaa aaactacctg
     1321 tttaggtagt tttttaaatg taatagatta aaacactagt tcatttcttg ttaaatattg
     1381 atagttatct tatagataaa tttgtccttt agtgtagcgg taatttttag gattttttgg
     1441 tggtataaat gttcttaata aagttaatag tcctacttta ccgcaaagca taacgaatat
     1501 aataattatt ttagtaatac catgatattc tgtggtaagg ttcatactta accctactgt
     1561 tccgaatgca gaaaccactt cgaataataa cttgattaat gatatgttcg gattaattat
     1621 cgataatata aaagtaatga tactgataaa tagaaatgag atattaatgg taacaataga
     1681 tagttttata tgtttgtcag atatttcttt attgaatact gaaacattat tttctttacg
     1741 tatataattt agtacaaaaa taaacgctac tgcaaaagta gttattttaa ttcctccagc
     1801 tgcactgaga ggggcaccac caataaacat aagtagcatt aacattaagg cggtagattt
     1861 gttaatgctt gctatatcta tactgttaaa acccgctgtt cgtgttgtta ctgattggaa
     1921 aaaagaattt ccgatttttt caactagtcc catatgttgc atagtattaa actgttctaa
     1981 taaaaagaat gtaatagctc ctataattat taggatacta gttgtagtta agactaattt
     2041 agaatgtaaa gataatttac tcaatttttt acaattaata aagtctatca cgacaaaatg
     2101 tccaatacct ccaaatatta tgagtattga gattgtaata atgacaattg gatcactaga
     2161 ataatctatt aagttattct taaaaagggc aaatccagca ttattaaaag ctgatactga
     2221 tgtgaataag cttaaaaata aacctttgcc tataccaaat tttggtataa aagataaaca
     2281 caaacaaatc ataccaatta attcagtgac taaactataa atagccaagt gtttaattag
     2341 tttaataaca ccaccaagtt cgtcaatatt ccatgtaacc ataatcaaga atctattttt
     2401 cattgatatc tttctattta aaaatactag tgtcaatagg gttacggtca cgatacccag
     2461 accacctatt tgaattaata atagtattac tatttcacca agtatattaa actgtgatcc
     2521 tatatcaact ggggataggc cagtaactgt aaatgcactt gaagctataa atagggcatc
     2581 taaaaaagat attggctttt taccagtgaa aggtaaatac aataaaagtg cacctatgat
     2641 agttgtagag aagaaaagca ttaaataaaa atataaaggt ttgtggactt tgttcatttt
     2701 aatttcatac tcctttatat tataaattaa taattagata atatcataaa tgaaaataga
     2761 aatgttactg atgtgtatta ctaacaggcg ttgactaatt cttttaatat tttataattg
     2821 aaaatgaata tcaattaaaa aacaaaagga tgatattatg aaaagattaa ttggaatttt
     2881 attatgtaat ttatttattt tgactgcgtg ttcagcatct gtcgataaaa caagtaactc
     2941 gacaaagact acagactata aaattgaaaa tggtgaaaca ctgaaagtac cagagaaacc
     3001 taaaagagtt gctgtattaa ctggatttta tgttggtgat tttataaagt taggaatcaa
     3061 accaattgct gtttcagata taactaaaga ttcttcaatt ttaaaaccct atttaaaagg
     3121 ggttgattat attggagaaa atgatgttga aagagttgct aaagcaaaac cagatttaat
     3181 tgttgtagat gctatggata aaaatataaa aaaataccaa aaaatagcgc caacaatccc
     3241 atatacatac aataaataca atcataaaga aatattaaaa gaaataggca agttgactaa
     3301 taatgaagat aaagctaaaa aatggattga agagtgggac gataaaacta gaaaagataa
     3361 aaaagaaatt caaagtaaaa ttggtcaagc aacagcatct gtgtttgaac cagatgaaaa
     3421 gcaaatatac atatataact ctacatgggg tcgtggtttg gatattgttc atgatgcatt
     3481 cggtatgcca atgacaaagc aatataaaga taaattacaa gaagataaaa aaggctatgc
     3541 ttccatttca aaagaaaata ttagtaaata tgctggtgat tatatatttt taagtaaacc
     3601 ttcgtacgga aaatttgatt ttgaaaaaac acatacatgg cagaatattg aagctgtaaa
     3661 aaaaggacat gtaatttcat ataaagcaga agattattgg ttcacagatc ctattacatt
     3721 agaacatttg agaagtaaat taaaaaaaga aattttaaat aaaaaataat
//
LOCUS       DAPSKH010000108         3666 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPSKH010000108 DAPSKH010000000
VERSION     DAPSKH010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3666
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.112"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            34..324
                     /locus_tag="RPH49_002583"
     CDS             34..324
                     /locus_tag="RPH49_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125692.1"
                     /translation="MGKEIYLDPIEFQNVLEKFEKGSSEISEVSISSIKDAKNEIILE
                     SIVELEKIIDDLSKAMKTYSKMIGSDKEAMDKIASTMQRNDKDNANKIANRN"
     gene            337..1599
                     /locus_tag="RPH49_002584"
     CDS             337..1599
                     /locus_tag="RPH49_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125693.1"
                     /translation="MPRLVNSELEEYFNKTNDVKTKLNEVLYNHYTQCYFLSKTGSIK
                     GKTADSIKKYVESAHISTISRAINLMDKLEASVKHLKELGEKCDKSSNAKIGLQTLNE
                     TKKGVVSKKKEFIDLTSNSPAILSEASEFIDTVSLGKDNVESDYNESSKKIDRTKEKL
                     KTMDQTGKQSLESLSNDVRGLITQINKLNNEYHDKNGIIVSKINSITKENWYKNETNK
                     GEFKKMKADHPVAYAEGDETIGRTQAISKDGHIVGTAEIGKVSGIAYRSDDSMGVKGD
                     AKVAGLDGKVKYENVEGKAGLEVGSVKGSAEISNSHISAIAEAQLIDAEAQLRFGSED
                     NNLHVKGDAKVLSASASGSLGADGVEAKAEAVGANTGVEGGFALSGLNFDFGASIGAQ
                     AGGGVNVGKKGIEVDAKFILGGKIKITW"
     gene            1612..2025
                     /locus_tag="RPH49_002585"
     CDS             1612..2025
                     /locus_tag="RPH49_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5082 family protein"
                     /protein_id="HDY5125694.1"
                     /translation="MSKSSLILEKNYKLQQSAETKTKIAELNDKIERATRIKNKLNDL
                     KKEVKEHRTNSKNIFKEYSYWKGENNSKWEEKSESELISGSITNCIKNIDDNIDRLID
                     KITEMQNEVNSLGSTLSVLENAINSIAAAIEKLTN"
     gene            2036..2509
                     /locus_tag="RPH49_002586"
     CDS             2036..2509
                     /locus_tag="RPH49_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5083 family protein"
                     /protein_id="HDY5125695.1"
                     /translation="MEKIKRINKIFLSFEVIPFAMMILLAFLPVIAGIINNRLQYGRD
                     FGDRVSFYCYISIMVAYAITILLEIIFYFILLKNYQYDQNNIELANRVKVTKVLSILY
                     MIPGLYAIACYFRFIHVRSFRENKKSGQPAYHFWEFFIKPNRKPIELKDFFIKNR"
     gene            2524..2898
                     /locus_tag="RPH49_002587"
     CDS             2524..2898
                     /locus_tag="RPH49_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4467 domain-containing protein"
                     /protein_id="HDY5125696.1"
                     /translation="MKRLIIGVLIIMMSIINYGCGNEQNENKYQSQINKVMKIQQETH
                     KEMVKKSNEVNPEFNKDKVNTYVFDDGKLIIISYKLFKDKDQMFYATYEFKNDKIYYK
                     RDINPKTYVKEHQSDYKDIKVK"
     gene            2916..3305
                     /locus_tag="RPH49_002588"
     CDS             2916..3305
                     /locus_tag="RPH49_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020361182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDY5125697.1"
                     /translation="MEKLIKVTSLIGIIIQSFLTLLFLIFLILSATGIIQPELTTTVN
                     GEQTIQSPETAQATFVTIFAILFVVSLASDLLGIIAMKKLFVNNRASGILYIIGAVIS
                     ANLLTFIAWLISGISVLRYNKIGKEVS"
     gene            3307..>3666
                     /locus_tag="RPH49_002589"
     CDS             3307..>3666
                     /locus_tag="RPH49_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000878106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5084 family protein"
                     /protein_id="HDY5125698.1"
                     /translation="MKYTWWILLTIAGILSLTSVYGFILCLGSFGMLALNVMWLFVYT
                     PHKNSKALESISKPTIILSIIGTYAVFIFMSILFYFVMKARFMEIGIKLYGEPFNMFG
                     IPLFIIGIILFTIGTVFV"
BASE COUNT         1473 a          376 c          694 g         1123 t
ORIGIN      
        1 taattttaaa attaactttg aggaggttta agtatgggga aagaaattta tttagatcca
       61 attgaatttc aaaatgtatt agagaaattt gaaaaaggat caagtgagat tagtgaagtt
      121 tcaatttcta gtataaaaga tgctaaaaat gaaattatat tagaaagtat agttgaacta
      181 gaaaaaataa ttgacgactt atcgaaagcg atgaaaacgt attctaagat gattggcagc
      241 gataaagaag caatggataa aatagcatca acaatgcaac ggaatgataa agataatgca
      301 aataaaattg caaataggaa ttagggaggg gaaaatatgc ctagattagt taattcagag
      361 ttagaagaat attttaataa aacaaatgat gtgaaaacga aattaaatga agtattatat
      421 aatcattaca ctcaatgtta ttttttatct aaaactggta gtataaaagg aaaaacagcg
      481 gatagtataa agaaatatgt tgaatcagca catataagca caatttctag agctattaat
      541 ttaatggata agttggaagc atcagtaaag cacttaaaag aacttggaga aaaatgcgat
      601 aaaagtagta atgccaaaat tggtttacaa actttgaatg aaactaaaaa aggtgtggtc
      661 tcaaaaaaga aggaattcat agatcttaca agtaattccc cagcaattct atctgaagca
      721 tcagaattta ttgatactgt gtctttaggg aaagataatg tagaaagtga ttacaatgaa
      781 agttccaaaa aaatagatag aactaaagaa aaacttaaga ctatggatca aacaggtaag
      841 caatcactag aaagtctaag caatgatgta agaggattaa taactcaaat aaataaattg
      901 aataatgaat atcatgataa aaatggaatt atcgtatcaa agataaactc cattacaaaa
      961 gaaaattggt ataaaaatga aactaacaag ggtgaattta aaaaaatgaa agcggatcat
     1021 cctgttgctt atgcagaagg agatgagaca ataggtagaa ctcaagcaat ttctaaagat
     1081 ggacatatag ttggtacagc tgaaataggt aaagttagtg gaatagcata tcgaagcgac
     1141 gattcgatgg gggttaaagg agatgctaaa gtagctggat tagatggtaa ggtaaagtac
     1201 gagaatgttg aaggtaaggc aggactcgaa gtagggagtg taaaaggttc agctgaaatt
     1261 agtaactcgc atatatctgc tattgcagaa gcgcaattaa ttgatgcgga agcacaatta
     1321 agatttggat cagaagataa taatttgcat gtaaaaggag atgcaaaagt tttgtcagca
     1381 agtgcgagtg gatctttagg tgctgatgga gtagaagcga aagctgaagc agtcggagct
     1441 aatacagggg ttgaaggtgg ttttgcactt agtggattaa attttgattt tggcgcgagt
     1501 attggggctc aagctggggg aggtgtaaat gttggcaaaa aaggaattga agttgatgct
     1561 aaatttatac ttggaggaaa aattaaaatt acatggtaaa ggaagaataa aatgtcgaaa
     1621 tcatctttaa tattggaaaa gaattataaa cttcaacagt cagcagaaac taaaaccaaa
     1681 atagcagaat taaatgataa aatagaaaga gcaacacgaa ttaagaataa attaaatgat
     1741 ttaaaaaagg aagtgaaaga gcatagaaca aattcaaaga atattttcaa agaatattcc
     1801 tattggaagg gagaaaataa ttcgaaatgg gaagagaaaa gtgagagtga actcataagt
     1861 ggttcaataa caaattgtat aaaaaatatt gatgataata tcgatagact catcgataaa
     1921 attaccgaga tgcaaaatga agttaattca ttgggtagta cattatctgt actagaaaat
     1981 gcaataaatt caatagctgc tgctattgaa aaattaacta attaaaggag tagaaatgga
     2041 aaaaataaag agaataaaca aaatattttt atcatttgaa gttattccat ttgcaatgat
     2101 gattttactg gcgtttctac cagttattgc aggtataatt aataatcgtt tgcagtatgg
     2161 tagggatttt ggcgatagag taagctttta ttgttatatt tcaattatgg ttgcatatgc
     2221 aattaccatt ttgttagaaa ttatttttta ctttatttta ttgaaaaact atcaatatga
     2281 tcaaaataat attgaattgg ctaatagagt gaaagttaca aaagtactgt cgattttgta
     2341 tatgattccc ggattatatg cgattgcatg ctattttaga tttatacatg ttcgctcatt
     2401 tagagaaaat aaaaaatctg gacagcctgc ttaccacttt tgggaatttt ttataaaacc
     2461 taatcgaaaa ccgatagagt tgaaagactt ttttattaaa aatagataat taaggagtaa
     2521 ccaatgaaaa gattaattat aggagtgtta attataatga tgagtataat caattatggt
     2581 tgtggtaatg agcaaaatga aaataaatat caaagtcaaa ttaataaagt aatgaaaatt
     2641 caacaagaaa ctcataaaga gatggttaaa aagagtaatg aagttaatcc tgaatttaat
     2701 aaggataaag taaatactta tgtatttgat gatggcaaat taattatcat cagctataag
     2761 ttatttaaag ataaagatca aatgttttac gcgacttacg agtttaaaaa cgacaaaatt
     2821 tattataaga gagatattaa tcctaaaaca tacgtgaaag aacaccaatc agattataaa
     2881 gatattaaag taaaataatt ttaaggagta ggaaaatgga aaaattaatc aaagtgacgt
     2941 ctttaattgg aattattatt caaagttttt taacattgtt atttttaata tttttaattt
     3001 tatcagcaac agggattata cagccagaat tgaccacaac tgttaatggt gaacaaacta
     3061 tacaaagtcc agaaactgct caagcaacat tcgtgacaat atttgcaata ttatttgttg
     3121 tttctttagc ttcagattta ttaggcatta tagctatgaa aaagttgttt gtgaataata
     3181 gagcgagtgg cattttgtat attattggtg cagtaatcag cgccaattta ttaacattta
     3241 ttgcttggtt aataagtggg atttctgttt taagatataa caaaatagga aaagaagtgt
     3301 catagcatga aatatacttg gtggatactt ttaacaattg cagggatttt aagtttaaca
     3361 agtgtttatg gatttatttt atgtttaggt agctttggaa tgttggcact gaatgtcatg
     3421 tggctatttg tttatacacc gcataaaaat tctaaagcac ttgaatctat atcaaaacca
     3481 acgataattt tatcaatcat tgggacatat gcagtattta tatttatgtc tatcttattt
     3541 tacttcgtaa tgaaagctag gtttatggaa attggaataa aactttacgg tgaacctttt
     3601 aatatgtttg gaataccatt attcattatt ggcatcattt tatttacaat cggtacagta
     3661 ttcgtt
//
LOCUS       DAPSKH010000109         3613 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPSKH010000109 DAPSKH010000000
VERSION     DAPSKH010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3613)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3613)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3613
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.113"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            315..1040
                     /locus_tag="RPH49_002590"
     CDS             315..1040
                     /locus_tag="RPH49_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL14"
                     /protein_id="HDY5125699.1"
                     /translation="MKKNIMNKLVLSTALLLLGTTSTQLPKTPISFSSEAKAYNISEN
                     ETNINELIKYYTQPHFSLSGKWLWQKPNGSIHATLQTWVWYSHIQVFGAESWGNINQL
                     RDKYVDIFGTKDEDTVEGYWTYDETFTGGVTPAATSSDKSYKLFLKYSDKQQTIIGGL
                     EFYKGNKPVLTLKELDFRIRQTLINNKKLYNGEFNKGQIKITGGGNNYTIDLSKKLKL
                     TDTNRYVKNPRHAEIEVILEKSN"
     gene            1106..1837
                     /locus_tag="RPH49_002591"
     CDS             1106..1837
                     /locus_tag="RPH49_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL13"
                     /protein_id="HDY5125700.1"
                     /translation="MLNEKNITKKIILSSALLLLGAVSTQLPNTPISSKSEAKAYYIN
                     QEETNVSELIKYYTQQHLTFSNKWLWQKDNGTIHATLLQISWYSHIQVFGPESWGNIN
                     QLRDKYVDIFGIKDQETIDSYALSQETFTGGVTPAAKPNDKHYKLNVTYKDKDETFIG
                     GYPFYTGNKPVLTLKEVDFRIRQTLIKNKKLYQDKYNKGQLTITGDDNNYTIDLSKRL
                     PSTDANKYVKNPQNAKIEVTLEKSN"
     gene            1947..2663
                     /locus_tag="RPH49_002592"
     CDS             1947..2663
                     /locus_tag="RPH49_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superantigen-like protein SSL12"
                     /protein_id="HDY5125701.1"
                     /translation="MKKNITNKIILTATLLILGTSSAQLPNTPIGFSSEAKAYHIGQD
                     ETNINELIKYYTQKPLTFSNRWLYQYDDGNIYVEFKRYSWSAHIRLWGAESWGNINQL
                     RDRYVDVFGLKDKDTRRLWWVYTDTFTGGVTPAASSSDKPYNIYVQYKDKLQTFIGAH
                     KIYQGNKPVLTLKEIDFRVRESLIKNKILYNENRNKGNIHITGGGNNFTIDLSKRLHS
                     DLANVYVKNPQKITVEVLID"
     gene            complement(3057..3281)
                     /locus_tag="RPH49_002593"
     CDS             complement(3057..3281)
                     /locus_tag="RPH49_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125702.1"
                     /translation="MLIEERGLKMKELNEIINAIQFLFESESGYKISKNSGVPYQTVQ
                     DLRNGKTKIEDARFRTIIKLYSYYATLKEQ"
     gene            complement(3238..3384)
                     /locus_tag="RPH49_002594"
     CDS             complement(3238..3384)
                     /locus_tag="RPH49_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125703.1"
                     /translation="MKLFYIAFLIIIWLNIFLGNEIIHTLTVLITTLYIVNRRKRIKN
                     ERVE"
BASE COUNT         1343 a          567 c          518 g         1185 t
ORIGIN      
        1 tttaagtagt aggaaattat taaaataagt actacattta aagtataact aattttcaag
       61 tagttagaaa attcaattat caaacaattt aatgcaattg attagagaat aattttaacg
      121 tgtcgttttt aatatataac tctcgcctac tttattaggt actgtttctg tccaaaaatt
      181 aaaaatgata agttttgctt aaataacact actaactgtt taagtttatt taacatagtt
      241 ttagctttta tttaattccg aatcggtgta aaagcttata tactttgggt aattcacgca
      301 aaggagattt tcatatgaaa aagaacatca tgaataaatt agttttatca acagcattgt
      361 tacttttagg aaccacatca acacaacttc ctaaaacgcc aatcagtttt tcatctgaag
      421 caaaagccta taatatcagt gaaaacgaga ctaatatcaa tgaactaatc aaatattaca
      481 ctcagccgca tttttcatta tctggaaaat ggctatggca aaagcccaat ggtagcattc
      541 atgcaacatt gcaaacgtgg gtttggtata gtcatattca agtatttggt gctgaaagtt
      601 ggggaaacat taatcagtta agagataaat acgttgatat attcggaact aaagatgagg
      661 atacagttga aggttactgg acttatgatg aaacatttac aggtggtgta acacctgcag
      721 ctacatcatc cgataagtct tataaattat ttttaaaata tagcgataaa cagcagacta
      781 tcatcggtgg tctcgaattt tacaaaggaa ataaaccagt attaacttta aaagaactag
      841 atttccgtat ccggcaaaca ttaataaata ataaaaagct atataacgga gaatttaata
      901 aaggtcaaat taagattacg ggtggcggta ataattatac gattgattta agtaagaagt
      961 taaaattaac tgacacaaac cgttatgtta aaaatcctcg acatgcagaa attgaagtca
     1021 ttcttgaaaa atctaattaa ccttaattgc ggagtaaata ctaaaattat ttaagtaacc
     1081 cttatttata aaaaatacaa ggagcatttt aaatgaaaaa aacattacga aaaaaattat
     1141 tttatcatca gcgttgttac tattaggcgc tgtatcaaca caacttccta acacaccaat
     1201 cagttctaaa tctgaagcta aagcttatta tattaatcaa gaggaaacaa atgtaagtga
     1261 gttaatcaag tattacactc agcaacattt aaccttttca aataaatggt tatggcaaaa
     1321 agataatggc acaattcatg caacgttact tcagatatca tggtatagcc atattcaagt
     1381 atttggccct gaaagttggg gtaatattaa tcaattaaga gataaatatg tagatatttt
     1441 cggcataaaa gaccaagaaa ctattgactc atatgcacta tctcaagaaa catttactgg
     1501 tggcgttaca cctgcagcaa aacctaacga taaacactat aaattgaatg taacatataa
     1561 agataaagat gaaacattta ttggtggata tccattttat acaggtaata agccagtttt
     1621 aactttaaaa gaagttgatt tccgtatccg acaaacatta attaaaaaca aaaaattata
     1681 tcaagataaa tataataaag gtcaactcac gattactggt gacgataata attacacaat
     1741 tgatttaagt aagagattac cgtcaactga cgcaaataaa tatgttaaaa atcctcaaaa
     1801 tgccaaaatt gaagttaccc tcgaaaaatc taactagtat cgaaatcgga gtcaacaaat
     1861 aataatctca ttcattatat tgacgccgct cacttttata tttgatattc ctcgcaatga
     1921 taaatccaca gaaaggagat gttcaaatga aaaagaacat cacgaacaaa ataatattaa
     1981 cagcaacatt gttaatatta ggtacttctt cagctcaact tcctaacaca ccaatcggtt
     2041 tttcatctga agctaaagct tatcatattg gccaagacga aacgaacatc aatgaattaa
     2101 tcaaatatta cacacaaaag cctctcacat tttcaaatag atggttatac caatatgatg
     2161 acggcaacat ttatgttgaa tttaagcgtt attcttggtc tgcacatata cgcttatggg
     2221 gtgctgaaag ttggggcaac attaatcaat taagagaccg ctatgtagac gtgtttggtt
     2281 taaaagacaa agacactaga cgattatggt gggtatatac tgatacattt acaggtggtg
     2341 ttacacctgc agcatcgtct tctgataagc cttataatat ttatgtacaa tataaagata
     2401 aactacaaac atttatcggc gcacataaga tatatcaagg taacaaacca gttttaacgt
     2461 taaaagaaat tgatttccga gtacgtgaat cattaataaa aaataaaata ctatataatg
     2521 aaaatcgcaa taaaggtaat attcatatta ccggtggtgg taataacttt acaattgatt
     2581 taagtaaaag attacattct gatcttgcaa atgtttatgt taaaaatcct caaaaaataa
     2641 cagtcgaagt cctcattgat taaataaggt agtatgattt atatcgaaaa tactaaggat
     2701 aaacaataat tgagtaatac tacaaaatgt atcaataata tttacacaat atttaaatta
     2761 gtacacagaa tattaaatgg gatttggagt ctaatagaaa tgcaaaatca ttctctgtgt
     2821 tgggggccgc tccaacttgc attgtctgta gaatttcttt ttgaaattct ctgtgttggg
     2881 gcccatcccc aacttgcaca ttattgtaag ctgacttttc gtcagcttct gtgttggggc
     2941 cccaccccat aattgaaaaa tgtttgttac atgggcattt ttgtttggtc aatatttgtc
     3001 tatataatat tgtagagcct aagacgtggt tacgttttag gctcttaatt caattattac
     3061 tgctctttta atgtagcata ataactatat agttttataa tcgttctaaa tctagcatct
     3121 tctattttcg ttttaccatt cctcaaatct tgcacggtct gatacggcac ccctgaattt
     3181 ttcgatattt tgtagcctga ttcagactca aacaaaaatt gaatagcgtt tattatttca
     3241 ttcaactctt tcatttttaa tcctctttct tctattaaca atatacaatg ttgttattaa
     3301 aacagtcagt gtatggatga tttcatttcc taaaaatata ttcagccata taataattag
     3361 aaatgcaata taaaatagtt tcattataat cccctatcat ttttatattt atcactttcc
     3421 atttagtttc aacattaaaa gctaacctag gtttaagatt atcttataac gcctataact
     3481 agaagtctgc attttatctt gtatataaca ttttataatg ttacactaca cctttttata
     3541 tttttcacaa gaagttttca cgaattatta tatttaaact cacccatatt ccaacacaat
     3601 taatttttct cta
//
LOCUS       DAPSKH010000110         3566 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPSKH010000110 DAPSKH010000000
VERSION     DAPSKH010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3566
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.114"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..67
                     /locus_tag="RPH49_002595"
     CDS             <1..67
                     /locus_tag="RPH49_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDY5125704.1"
                     /translation="NDDDISKFNALFEDVEQFLNI"
     gene            257..973
                     /locus_tag="RPH49_002596"
     CDS             257..973
                     /locus_tag="RPH49_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDY5125705.1"
                     /translation="MGRKWNNIKEKKAQKDKNTSRIYAKFGKEIYVAAKSGEPNPESN
                     QALRLVLERAKTYSVPNHIIEKAIDKAKGAGDENFDHLRYEGFGPSGSMLIVDALTNN
                     VNRTASDVRAAFGKNGGNMGVSGSVAYMFDHVATFGIEGKSVDDILETLMEQDVDVND
                     VIDDNGLTIVYAEPDQFAVVQDALRAAGVEEFKVAEFEMLPQTDIELSEADQVTFEKL
                     IDALEDLEDVQNVFHNVDLK"
     gene            973..1446
                     /locus_tag="RPH49_002597"
     CDS             973..1446
                     /locus_tag="RPH49_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDY5125706.1"
                     /translation="MKTAEQWINELQLESHPEGGFYRETIREVLKDGHRAPFSSIYFL
                     LTDDNISHFHRIDADEVWYYHAGDSLTIHMINPDGEYMTATLGTDIQNGDVLQYVVPK
                     GTIFASSIENSNTFSLVGCMCQPAFEFKQFELFKQSELFDQYPHLKSVIEKYALK"
     gene            1539..1655
                     /locus_tag="RPH49_002598"
     CDS             1539..1655
                     /locus_tag="RPH49_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125707.1"
                     /translation="MLQMFLMKIALNDFENDKSVLFIFLKNHFYEEMCVLSN"
     gene            1800..2447
                     /locus_tag="RPH49_002599"
     CDS             1800..2447
                     /locus_tag="RPH49_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDY5125708.1"
                     /translation="MKVKYIDKRHWRRLIDREYTEVKVNNNRFKGIIGLVTMKKVRDP
                     LEVTVVGQNIIVADDNYKWLQILPEKKRYSITVMFDNKGNPLEYYFDINIKNITQKGN
                     ARTVDLCLDVLALPSGEYELVDEDDLMFALESEQITKKQFHEAYMIAHQIMAELENDF
                     KGFQKKIMYCFNKINAKAQKNHQKPQNKTNFEKSKQIKPKQYNQTKNHQQQKKTK"
     gene            2561..3427
                     /locus_tag="RPH49_002600"
     CDS             2561..3427
                     /locus_tag="RPH49_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDY5125709.1"
                     /translation="MKIEDYRLLITLDETKTLRKAAEILYISQPAVTQRLKAIENAFG
                     VDIFIRTKKQLITTTEGTMIIEHARDMLKRERLFFDKMQAHIGEVNGTISIGCSSLIG
                     QTLLPEVLSLYNAQFPNVEIQVQVGSTEQIKANHRDYHVMITRGNKVMNLANTHLFND
                     DHYFIFPKNRRDDVTKLPFIEFQADPIYINQIKQWYNDNLEQDYHATITVDQVATCKE
                     MLISGVGVTILPEIMMKNISKEQFEFEKVEIDNEPLIRSTFMSYDPSMLQLPQVDSFV
                     NLMASFVEQPKA"
BASE COUNT         1357 a          446 c          662 g         1101 t
ORIGIN      
        1 aaatgatgat gatatatcta aatttaatgc tttatttgaa gatgtagaac aatttttaaa
       61 tatttaattg aaattgagtg tcgaaagcat agaaattgct tatcggcaca tttttaattt
      121 atacatattt taaaactaag taacagattg aagaaatcgt agttcaataa tgttaattgt
      181 gaaaatgtat ataatcataa aaaaatcatg tataatatat gttgttaatt aaacagttcg
      241 aaagcgagat gacattatgg gacgtaaatg gaataacatt aaagaaaaaa aggcccaaaa
      301 ggataaaaat acaagtagaa tatatgcgaa atttggtaag gagatttatg ttgcagcaaa
      361 atctggtgaa ccaaacccag aatctaacca agctttaaga ttggtacttg aacgcgctaa
      421 gacatattca gtaccgaatc atattattga aaaagcaata gataaagcta agggtgctgg
      481 agacgaaaac tttgatcacc taagatatga aggatttggc ccaagcggat caatgcttat
      541 tgttgatgcg ttaacaaaca atgtaaatcg tactgcatct gatgtgcgtg ctgcttttgg
      601 taaaaacggc ggtaatatgg gtgtatctgg atcagttgct tatatgtttg accatgtggc
      661 aacgtttggt attgaaggta aatctgttga cgatatactt gaaacattaa tggaacaaga
      721 tgtagatgta aatgatgtga ttgacgacaa tggattgaca atagtctatg ctgaaccaga
      781 tcaatttgcg gttgttcaag atgcgcttcg tgcagctggt gtagaagaat ttaaagtagc
      841 agaatttgaa atgttacctc aaacagatat tgagctttct gaagcggacc aagtaacatt
      901 tgaaaaatta atcgatgcat tagaagattt agaagatgta caaaacgtat tccataatgt
      961 ggatttgaaa taatgaaaac agcagaacaa tggattaatg aattacaact cgaatcgcat
     1021 cctgaaggtg gtttttatag agagacaatc cgagaagtat taaaagatgg acacagagcg
     1081 ccgtttagca gtatttattt tttacttaca gatgacaata tttcgcattt tcatcgaatt
     1141 gatgctgatg aagtatggta ctatcatgcc ggtgattctc taacaattca tatgataaat
     1201 ccggatggag aatatatgac tgcaacattg ggtactgata tccaaaatgg agatgtattg
     1261 caatatgtag tgcctaaagg aacaattttt gcttcttcaa ttgaaaattc aaatactttt
     1321 agtttagtag gttgtatgtg tcaaccggca tttgagttta agcaatttga attgtttaag
     1381 caatctgaat tatttgatca atatccgcat cttaaatcag taatcgaaaa atatgcttta
     1441 aaataaaaaa gaatcaatga agtggtttga aggttgttaa taaacctttg agtcacttca
     1501 tttttatatg tattcttgat tgaatcagaa tagatttgat gcttcagatg tttttaatga
     1561 aaatagcatt aaatgatttt gaaaacgata agagtgtgtt atttatattt ttgaaaaatc
     1621 acttttatga agaaatgtgt gtactatcta attaatattg tctattttaa gtaaattgaa
     1681 gcgagttgta gtaaaataat aataaatatt ttcatatgat taacaaaaac tataaaactg
     1741 tatcatgaca tgacatcatt tatgtagttt tatataataa tgacaaggag ttggtgactg
     1801 tgaaagtaaa gtatatagat aaacgtcact ggcgtcgcct aattgatagg gaatacacag
     1861 aggtaaaagt taataataat aggtttaagg gtattatagg cttagtcacg atgaaaaagg
     1921 ttcgtgatcc tttagaggtg acggtagttg gacaaaatat cattgtcgca gatgacaatt
     1981 ataaatggtt gcaaatacta cctgaaaaga aacgttatag tataactgta atgtttgata
     2041 ataaaggcaa tccattagaa tattattttg atataaatat caaaaatata acgcaaaaag
     2101 gtaatgcgcg tacagtagat ttatgtttag atgttttagc attaccaagt ggtgaatatg
     2161 agttggtaga tgaagatgat ttaatgtttg cattagaaag tgagcaaatt acaaaaaagc
     2221 aatttcatga agcatatatg attgcacatc aaattatggc agagttagaa aatgatttta
     2281 aaggattcca aaagaaaatc atgtactgct ttaataaaat taatgcaaag gctcaaaaaa
     2341 atcatcaaaa gccacaaaat aaaactaatt ttgaaaaaag caaacaaata aaacctaagc
     2401 aatataatca aactaaaaat caccaacaac aaaagaaaac taagtaattc aagctgcagc
     2461 cataccaata aaattggtga aaattattcg ttagtaatga actcttgaat gctcgtagtc
     2521 atgaaagttc aataattgaa taatttatgg gggggaaatt atgaagattg aagactatcg
     2581 tttactaata acattagacg aaacgaaaac gttacgtaaa gcggctgaaa ttttatatat
     2641 atctcaacct gctgttacac aaagactaaa agctattgaa aatgcttttg gagtagatat
     2701 ttttatcaga acaaaaaaac aattgattac aacaactgaa ggaacaatga ttattgagca
     2761 tgcccgtgac atgttgaaaa gagagcgatt attttttgac aaaatgcagg cacatattgg
     2821 tgaagtgaat ggaacaatat caatcgggtg ttcttctttg attggacaaa ccttacttcc
     2881 tgaagttttg agcctatata atgcccaatt tcctaatgtt gaaatacaag tgcaagttgg
     2941 ttcaactgaa caaattaaag caaatcatag agattatcat gttatgataa ctcgtggaaa
     3001 taaggtaatg aatttagcta acacacactt atttaatgat gatcattatt ttatttttcc
     3061 aaaaaataga cgagatgatg ttacaaagtt accatttata gagtttcaag ctgacccgat
     3121 ttatataaat caaataaaac aatggtataa cgataattta gaacaagatt accatgcaac
     3181 tattacagtg gatcaagtag caacttgcaa agaaatgttg attagtggtg taggtgttac
     3241 aatcttgcca gaaattatga tgaaaaatat cagcaaagaa caatttgagt ttgaaaaagt
     3301 agaaattgat aatgaaccgc tgattcgttc gacatttatg agttatgatc cgagcatgtt
     3361 gcaattgcca caagttgatt cgtttgtaaa tctcatggcg agctttgttg aacaaccaaa
     3421 ggcgtagtct taaactaatt taaggttagt atttaatttt aaactattcg gttaagttga
     3481 acgcagttgt ttgctaatgc accaacagca aaagagcccc taattaataa attaaaaggg
     3541 gacaaaggaa tacagttggt tgctaa
//
LOCUS       DAPSKH010000111         3383 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPSKH010000111 DAPSKH010000000
VERSION     DAPSKH010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3383
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.115"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            128..856
                     /locus_tag="RPH49_002601"
     CDS             128..856
                     /locus_tag="RPH49_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5067 domain-containing protein"
                     /protein_id="HDY5125710.1"
                     /translation="MKKVMGILLASTLILGACGHHQDSAKKESTSHKKKENDNEELNE
                     ELKEFKSKKNMDIKIKGDTIVSDKFEAKIKEPFIINEKDEKKKYIAFKMEITAKKDDK
                     DLNPSSISHDYINITQDDKNTVNKLRDGYLLSDKKYKDWTEHNQDQIKKGKTAQAMFI
                     YELRGDGNINLNVHKYSEDKTVDSKSFKFSKLKTEDFSHRAETREEVEKKEKEFEEEY
                     KKEQEREKEKEKHKDDDHSGLDEV"
     gene            1659..2381
                     /gene="sel"
                     /locus_tag="RPH49_002602"
     CDS             1659..2381
                     /gene="sel"
                     /locus_tag="RPH49_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type L"
                     /protein_id="HDY5125711.1"
                     /translation="MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVN
                     LKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDIFGISYKYGSNSRTI
                     YGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQD
                     EFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLK
                     IYKDNKTVDSTQFHLDVEISKR"
     gene            complement(2548..3348)
                     /gene="sec3"
                     /locus_tag="RPH49_002603"
     CDS             complement(2548..3348)
                     /gene="sec3"
                     /locus_tag="RPH49_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type C3"
                     /protein_id="HDY5125712.1"
                     /translation="MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEF
                     TGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAK
                     KYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLV
                     RVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIEN
                     NGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG"
BASE COUNT         1294 a          486 c          451 g         1152 t
ORIGIN      
        1 ttattacaag aattatttaa tatcatctta gaatctcaca aaatatcaac tttgtttaat
       61 tactcaaaac gataagtcgt ttagagtttt taaaataaat ttttgcgaaa taaaggagac
      121 atgttaaatg aaaaaagtaa tggggatatt attagcaagt acacttatct taggtgcttg
      181 tggacatcat caagatagtg caaaaaaaga gagcactagt cacaaaaaga aagaaaatga
      241 caatgaagaa ttaaatgaag aacttaaaga atttaaaagc aaaaaaaata tggatataaa
      301 aattaaaggc gatactattg ttagtgacaa atttgaagct aaaataaaag aaccgtttat
      361 catcaatgaa aaagatgaga aaaagaaata tatcgctttt aaaatggaaa ttactgctaa
      421 aaaagacgat aaagatttaa atccatcttc tatttctcat gactatatta atatcactca
      481 agatgataaa aatacagtaa ataaattaag agatggttat cttttaagtg ataaaaaata
      541 taaagattgg acagaacata accaagatca aattaaaaaa ggcaaaactg cacaagccat
      601 gtttatctat gaattaagag gtgatggaaa tattaattta aatgtccata aatactcaga
      661 agataaaaca gttgattcta aatcattcaa atttagtaaa cttaaaaccg aagatttttc
      721 tcatagagcg gaaacaagag aagaagtaga aaagaaagaa aaagaatttg aagaagagta
      781 caaaaaagaa caagaacgag agaaagaaaa agaaaagcat aaagatgacg accacagtgg
      841 tttagatgaa gtataaattt atgaatgctc gcattcaacg ttataatctt tactgttatt
      901 attgtcatta tagattagct tacttacact cataatgaca tactaattta attgttaaat
      961 ataataaaaa agagtagctc gcctactctt ttttgttgtt ttgaatgaag aattatctta
     1021 tataaagaat tttttttatg aacaatatta aaactcaaag ctcaactttt ttgacactta
     1081 tttgacacat attctttcaa cccttaacgc aaaatcttat atgtacacaa ctattaattt
     1141 ttcattcatg aaaatttgaa cctaagcaga tactatcata tcaaagtaca cagctaattt
     1201 aaccttcctc acaagaaaag ataaaaaaca taaaaaagag caaggtcaac gtgtcagaaa
     1261 attattttct tgacacatat ttgacacttg ctagattaaa accccattaa atcaaggttt
     1321 ccaagcatat ttttatggag acggcgggag ttcattaaag cgtttatcta ttcatgtata
     1381 actcgctata agcattgtca tatcaacgtt taaattggct actctattgt gtgtaaaatg
     1441 ttaaaattga taaaactata taaatttgtg cacccaacat cacctcataa ttaacgtatt
     1501 caaatacgta ttcactgcct gcaacgtgtg ggatgataca tatttttcta taactcttcc
     1561 tttataacct tttgtatttt ttatgaattt tctaaaattt attattcaac ttatatttat
     1621 aatgttatta taaatataat gaaaaggaag tgcctaatat gaaaaaaaga ttattatttg
     1681 taattgttat tactttattt attttttctt ctaatcatac agtcttatct aacggcgatg
     1741 taggtccagg aaacctaaga aatttttata ctaaatatga atatgtgaat ttaaagaatg
     1801 ttaaagacaa aaattcacca gaatcacacc gcttagaata ctcgtataaa aatgatacat
     1861 tgtatgctga atttgacaat gaatatataa ctagtgatct aaagggaaaa aatgtcgata
     1921 tttttggtat aagctataaa tatggttcta actctcgtac tatatatggt ggtgttacta
     1981 aagcagaaaa caataaatta gattcgccaa gaataatacc tataaattta attatcaatg
     2041 gcaagcatca aacagttaca actaaaagtg tttctacaga taaaaaaatg gttaccgcac
     2101 aagaaataga tgtcaaacta agaaaatact tgcaagatga atttaatatt tatggacaca
     2161 atgatactgg taaaggtaaa gaatacggca cttcttcaaa attttatagc ggttttgata
     2221 aggggagtgt agtattccat atgaatgatg gttctaattt ctcgtatgat ttattttaca
     2281 caggatacgg tcttccagaa agcttcttaa aaatttacaa agataataaa actgttgatt
     2341 caacacaatt tcatctagat gtcgaaattt caaaaagatg attccaatta ttatagttta
     2401 gattcactgt ataaataatc gcactttcta ttaatataga agtgaggttt aatctatata
     2461 tatgcatcct aaaaaggcaa gcaccgaagt acttaccttt caaatatatc taatactttc
     2521 actttttata tcaaaaacgg attaacatta tccattcttt gttgtaaggt ggacttctat
     2581 cttcacactt ttagaatcaa ccgttttatt gtcgttgtac atcattaaat atttagattg
     2641 gtcaaactta tcgcctggtg caggcatcat atcataccaa aaagtattgc cgttattttc
     2701 aataaatttt atatatcctg tttcatatgg tgaactgtta aactcataca aatttttttt
     2761 attaattaaa aaattcctag cttttatgtc tagttcttga gctgttacac ttttcttatc
     2821 agtttgtact tcaaaagaaa ttgtgtttct tttattttca taaactctta caagtacatt
     2881 ttgtaagttc ccattatcaa agtggtttcc ttcatgtttt gttattcctc catacataca
     2941 agttttacca cctgtaactt tacctacatt atctttggat gaaaaatagc agtttacata
     3001 gtaatttgat ccatacacat caactacttc atctttgtac ttctttgcta aatcttcatt
     3061 taataactct gttttcactt tgtcataatt tttcagtttt ttatcactaa tgttataaat
     3121 taaatcatgt gccaaaaatt tatctacaga cttaacttta gttgctgata cataatgatc
     3181 atcatataaa tatttcatat tacccatcgt accagtaaac tcacttgatt tgtgcaaatc
     3241 atctggcata gggtctggtt gactctctgc taaaacgttg ggtgtagaaa taactagtat
     3301 cagtgcgaat atcaaaatta cacgtgaaat aaataatctc ttatacattt tttatctcct
     3361 ttatccaaca ttcccaaaaa gta
//
LOCUS       DAPSKH010000112         3372 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPSKH010000112 DAPSKH010000000
VERSION     DAPSKH010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3372
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.116"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            161..1984
                     /locus_tag="RPH49_002604"
     CDS             161..1984
                     /locus_tag="RPH49_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002489465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDY5125713.1"
                     /translation="MNLEFKYLFLKLIVKEDWSLSNVFNTGAVKLNKIAEFFNEVYPN
                     LNSLLDCDINMLEKYWFSWLTKNNIPIKRKSSTIVFGDYEHKSGLASFLKNMYINLNK
                     FIDKREEWEKDKWDIRNLEKYGLSYNKTLTGNYLNFEKIESIKMRELAKKYLKNRLIT
                     GDIAFATARFYIRVLTRFFQNISKNKETRNSLNELDRCHIEAYIEFLFEYANSKNVQS
                     SRNFVREELKAIRRFLNDIASQNYDIAPSEDIRFLIYPQDFPKREKKNSSQIDYIPDF
                     VLEQLFEHINDLHKDLIPVVWIAFKTGLRISDVLTLKNNCLAKVNGKFSIITDIAKTF
                     VKGHRIPIDNELADIVAVLIANSKIKSTKDNNPNNYIFAIHKGKRKGMPFTQHMVRAH
                     LNHLAKTKNILDEQGEVFHFKTHQFRHTYAVKLLNGGADILTIQELLAHSSPEMTLRY
                     AKLLDDTKRKAFESVIDQGAFSFDVDGKIKNIQHSSELSEKALNSLWQEHKLNAMDNP
                     YGTCHARLSGDCPYMEAPPCLTCNSGKPCKDLAIGFSDLDVEKYELHIKSTVKSIELA
                     KNNNRQDMVEKHTNILNKYEEILGNIKDGNIIFGRSNRIKV"
     gene            1993..2358
                     /locus_tag="RPH49_002605"
     CDS             1993..2358
                     /locus_tag="RPH49_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125714.1"
                     /translation="MGKFNRQEQLKQLHAERKVKTEQKVSKAINELVRKNEEINFNIV
                     AKHSNVSKATLYNNSKIRKRIEELREQSKDIFVHKNNSDGKDALISSLKRRVKSLENE
                     KKRLKDEINTLYNKIYEDI"
     gene            complement(2387..2797)
                     /locus_tag="RPH49_002606"
     CDS             complement(2387..2797)
                     /locus_tag="RPH49_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YolD-like family protein"
                     /protein_id="HDY5125715.1"
                     /translation="MIPNPNAPDEYKYETDYRKIPRKYLNPKIPQGRGKIKWQAFATL
                     PQQFEILEQIIKDQNKIEKPLLTHDSLDNLDQIFQIKIQNDELCTISYWEDGSISNYT
                     GKILKIDTINGYFTFYDSTNTKHTFFNTNVYNIS"
BASE COUNT         1323 a          396 c          527 g         1126 t
ORIGIN      
        1 aaaaggagaa gtgctaataa ctgaaatata tgatgattac tttttaaaaa atgatgaatg
       61 gcacatttca gcttttaaca agttcgagca atttcaagat agtatcaaga actataaaga
      121 caaaagaaaa aatattttct ttaggattaa aagtgaaaat ttgaatttag aatttaaata
      181 cctttttttg aaacttatag ttaaagagga ttggtcttta tctaatgtat ttaatactgg
      241 agcagtgaaa cttaacaaga ttgctgagtt ctttaatgaa gtttatccaa atttaaattc
      301 tttactagat tgtgatatta atatgttaga aaagtactgg tttagttggt tgactaaaaa
      361 taatatacct ataaaaagaa aatcatcaac aatagttttt ggtgattatg aacataaaag
      421 tggactagct tcttttttaa agaatatgta tattaatcta aataaattta ttgataagcg
      481 agaagaatgg gaaaaagata aatgggatat tagaaattta gaaaaatatg gattgagtta
      541 taataaaaca ctaactggta attatttgaa ctttgaaaaa attgagtcaa ttaaaatgcg
      601 agaattagca aaaaaatatt taaaaaatcg tttgataact ggtgatatag catttgctac
      661 agcaagattt tatataagag ttttgactag gttttttcaa aatatatcta aaaataaaga
      721 aacaaggaat agtttaaatg aactagatag atgtcatatc gaagcatata tagaattttt
      781 atttgaatat gctaatagta aaaatgtgca aagttctagg aacttcgtta gagaagaatt
      841 aaaagcaatt agaaggttct taaatgatat tgctagtcaa aattatgata tagccccctc
      901 tgaagatata cgctttttaa tttatcctca agactttcct aagcgcgaaa agaaaaatag
      961 tagccaaatt gattatatcc cagattttgt attggaacag ctttttgagc atataaatga
     1021 tttgcacaaa gatttaatac ctgtagtttg gatagctttt aaaacaggac taagaatttc
     1081 tgatgtatta acattaaaaa ataattgtct tgcaaaagtt aatggaaagt tttcaataat
     1141 tactgatatt gctaaaactt ttgttaaagg acataggata ccaatcgata atgaattagc
     1201 tgatatagta gcagttttaa tagccaattc taaaattaaa agtacaaaag ataacaaccc
     1261 taataattat atttttgcta ttcataaagg aaaaagaaaa ggaatgccct ttacacagca
     1321 tatggtcaga gcacacttaa atcatttagc aaaaacaaaa aatattcttg atgaacaagg
     1381 tgaagtcttc catttcaaaa ctcatcagtt tagacatacc tatgcagtga aattgttaaa
     1441 tggtggagca gatatattaa ccatacaaga attattagca cattcctcac cagaaatgac
     1501 actcagatat gctaagttac ttgatgatac aaaaagaaag gcttttgaat cagttattga
     1561 tcaaggggct tttagttttg atgttgacgg taaaattaaa aatatacagc atagtagtga
     1621 attatcagaa aaagcattga attctttatg gcaagaacat aaattaaacg caatggacaa
     1681 tccttatggt acttgtcatg ctagattgag cggtgattgt ccatatatgg aagctccgcc
     1741 atgcttaact tgtaattctg ggaaaccatg taaggatcta gctattggat tttctgattt
     1801 agatgttgaa aaatatgaat tacatatcaa atcaacggtc aaatctatag aattagctaa
     1861 aaataataat agacaagata tggttgaaaa acatactaat atattaaata aatatgaaga
     1921 aatattaggt aatataaaag atggaaacat tatattcggg agaagtaata gaataaaagt
     1981 atagaggtta agatgggaaa atttaataga caagaacaat taaaacagtt acatgcagaa
     2041 cgaaaagtta aaaccgagca aaaagtttct aaagcaataa atgaattggt tcgaaaaaat
     2101 gaagaaatta actttaatat tgttgctaag cattcaaatg tatctaaagc tactttatat
     2161 aataatagta aaattcgaaa gagaatcgaa gagttacgtg aacaaagtaa agacatattt
     2221 gtacataaaa ataacagtga cggtaaagac gcattaattt cttcattaaa aaggagagta
     2281 aaatctttag aaaatgagaa aaagaggctc aaagatgaaa taaacacatt atataataaa
     2341 atatatgaag atatttaata cacaggtaaa gagaaataat tcaagtttaa gagatattat
     2401 acacattagt attaaaaaaa gtatgtttag tatttgtaga atcgtaaaat gtaaaataac
     2461 cattgattgt atcaattttc aaaatttttc ctgtatagtt tgaaatgctg ccgtcttccc
     2521 aatatgagat tgtacataac tcatcatttt gaatttttat ttgaaaaatc tgatctaaat
     2581 tatctaatga atcatgtgtt agcaatggtt tttctatttt attttgatcc tttataattt
     2641 gttctaaaat ttcaaactgt tgcgggagag tcgcaaaagc ttgccatttg atttttccac
     2701 gcccttgagg gattttaggg tttaaatatt ttcttggtat ttttctataa tcagtttcat
     2761 atttatattc atctggcgca ttaggatttg gaatcatgtt taccacctca tcatcattgt
     2821 agaacgtatg ttcttttttg gcaaggatta tataattttt taatgtgatt aattaattaa
     2881 ttaatttaaa ataagttatt ttttatatgg aaaagttgag taagattatc gagcatttat
     2941 aattatagta actggaatta tgatgtttgg tatgttaata gtattttctc ttttaaaaaa
     3001 tgtgaacata aaaaaataga gtctgggaca taaaccctag agaaatagcc agtaaatgag
     3061 ttttaacaaa ttcatttact ggcttcttta tttacaatac tccgtattgt tggctcgctt
     3121 tcttagggga cagcttcagc ctgtagtctt cagcttgtcc tgttccctca agagtctcgc
     3181 caaaatactt tgtatttata tgtaatttta cattgtaata ctttaaaaaa ataaagcact
     3241 ttcgtataat ttaataaaca tcactaaact aaattaacga ggtgccttat gtataaaaat
     3301 tataacatga ctcaacttac tctaccaatg gaaacttcag ttcttatccc cacaaatgat
     3361 atttcacgac at
//
LOCUS       DAPSKH010000113         3324 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPSKH010000113 DAPSKH010000000
VERSION     DAPSKH010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3324)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3324)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3324
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.117"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(268..717)
                     /gene="ndk"
                     /locus_tag="RPH49_002607"
     CDS             complement(268..717)
                     /gene="ndk"
                     /locus_tag="RPH49_002607"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDY5125716.1"
                     /translation="MERTFLMIKPDAVQRNLIGEVISRIERKGLKLVGGKLMQVPMEL
                     AETHYGEHQGKPFYNDLISFITSAPVFAMVVEGEDAVNVSRHIIGSTNPSEASPGSIR
                     GDLGLTVGRNIIHGSDSLESAEREINLWFNENEITSYASPRDAWLYE"
     gene            complement(809..1768)
                     /locus_tag="RPH49_002608"
     CDS             complement(809..1768)
                     /locus_tag="RPH49_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002463052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDY5125717.1"
                     /translation="MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVR
                     PAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWD
                     QTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
                     YLRRINRKTALLIQLSTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTE
                     KKLGKPVGSDLLNGHITLPILLEMRKNPEFKVKIEQLRRDSERKEFEECIQIIRKSDS
                     IDEAKAVSSKYLSKALDLISELPDGHPKSLLLSLTKKMGSRNT"
     gene            complement(1770..2495)
                     /locus_tag="RPH49_002609"
     CDS             complement(1770..2495)
                     /locus_tag="RPH49_002609"
                     /EC_number="2.1.1.163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="demethylmenaquinone methyltransferase"
                     /protein_id="HDY5125718.1"
                     /translation="MADNKANKEQVHRVFQNISKKYDRLNNIISFEQHKVWRKRVMKD
                     MGVRKGTKALDVCCGTGDWTIALSKAVGPTGEVTGIDFSENMLEVGKEKTASMENVKL
                     VHGDAMELPFEDNSFDYVTIGFGLRNVPDYLVALKEMNRVLKPGGMVVCLETSQPTLP
                     VFKQMYALYFKFVMPIFGKLFAKSKEEYEWLQQSTFNFPGKEELKRMFEEAGFINVRV
                     RSFTGGVAAMHLGYKEKDNTKGD"
     gene            complement(2498..3070)
                     /locus_tag="RPH49_002610"
     CDS             complement(2498..3070)
                     /locus_tag="RPH49_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heptaprenyl diphosphate synthase component 1"
                     /protein_id="HDY5125719.1"
                     /translation="METTVSKLERQIEERLKGVSEYESININHRLGKLLDSYDIPDVA
                     KVACLTIDTSMRHLDDITYNHLSKHSILIGDLISAHFYTLLAEINDLSFQNEISKAIV
                     EINELKSSLHHQALNDYEISQAIVKIETLFPYITLSHFGINIDESEIYNYLFEDMSDY
                     YPSYFKKYNQSEVKHYLHDIQKSYLKSRGN"
BASE COUNT         1039 a          621 c          419 g         1245 t
ORIGIN      
        1 attccattga ttttaagaac attaaaatcc ctaaaataat tgaaataata ttcttcattc
       61 tatcaacccc ttcttttagt ttagtttcat ttgataaaga atattcctct ctttttaata
      121 cgtgttacca aaaaaactat aaaatttttc aagtaattta ctacaacata aaaaacgggc
      181 cttgttatgt ataatcataa tgactaacca cataacaaaa ccctttctac ctttataaat
      241 aaatcgtaaa ggtttacagt ttaaatttta ttcatataac catgcatcac gtggtgaagc
      301 atagctagta atttcatttt cattaaacca tagattaatt tcacgttcag cagactctaa
      361 tgaatctgaa ccgtgaatga tatttctacc aacagttaaa cctaaatcac ctctaattga
      421 tcctggtgaa gcttctgaag gatttgtgct gccaataata tgtctagata cattaactgc
      481 atcttcacct tcaactacca ttgcgaacac tggtgctgat gtaataaatg aaattaaatc
      541 attataaaat ggtttacctt ggtgttcacc ataatgtgtt tcagcaagtt ccattggtac
      601 ttgcattaat ttaccaccga caagttttag tccttttctt tcaattcttg aaattacttc
      661 accaattaga tttctttgta ctgcatctgg tttaatcatt aaaaatgtac gttccacttt
      721 atgtatcccc ctgtgtttaa taggtttatg tatattacta ttatatatta acaggttggt
      781 aaagcgcttt caatactttt cataaatact acgtgtttct tgaacccatt tttttcgtca
      841 aacttaaaag tagtgatttc ggatgtccat ctggtaactc agaaatcaaa tccaaagctt
      901 tacttaaata cttcgaactt actgccttag cctcatcgat gctgtcagat tttctaatga
      961 tttggataca ttcttcaaat tctttacgtt cactatcacg tcgtaattgc tcaattttca
     1021 ctttgaattc tggatttttt ctcatttcca ataaaatagg caaagtaata tgaccattca
     1081 acaaatcact tccgaccggc ttacctaatt tcttttcggt acttgtgaag tctaatacat
     1141 catcaatgat ttggaagctc atacctatat aatgaccaat cattttcaat tttcgtacag
     1201 tctctttatc agattgagat gtaattgcac caacttcagt tgataattga attaacagtg
     1261 ctgttttgcg attgatacgt cgtaagtaat tgataattgt ctgttgactg ttaaattggt
     1321 cttgaaattg gaaaagttcc cctctacaaa catcaactat agattcagat attaattgat
     1381 gtacacgatt atctttaacg gccattaagt gttcaagtcc taatgccaat aaaaaattcc
     1441 cagttaaaat agcagttgtc tgatcccatt tctttgatat ggttaacttg cctcgacgct
     1501 tgtcgctttt atcaataacg tcatcatgaa caagtgttgc catatgaatt aactctaatg
     1561 cgactgcaac ttgatacgtt tgttcagacg tttgttcatc tttgccaaat tggctactca
     1621 gaattacaaa tgctgggcgt actcttttac caccagaaga taataagtgt aatgatgcct
     1681 gttctaatac agaatcttta ctttttattg ccttttcaag tcgttgttcc actttcttaa
     1741 tttcattgtt catgtttaac tttgccacgt taatcacctt tggtattatc tttttcttta
     1801 tagccaaggt gcattgcagc aacgccccct gtaaaactac gtactcttac atttatgaaa
     1861 cccgcttctt caaacatgcg cttcaactct tcttttccag gaaaattaaa cgtagattgc
     1921 tgtaaccatt catattcttc ttttgatttt gcaaataatt tcccaaaaat aggcataaca
     1981 aatttaaagt ataatgcata catttgttta aagactggca aagttggttg gctcgtttca
     2041 agacatacca ccataccacc tggtttaagt actctattca tttcttttaa cgcgactaaa
     2101 tagtctggca cattccttaa tccaaaccca attgttacat aatcaaaaga attgtcttca
     2161 aacggcaatt ccattgcatc accatgaaca agtttaacat tttccattga agcagttttt
     2221 tcttttccta cttctaacat attctcacta aagtcaatac cagtaacttc acctgttggt
     2281 cctacagctt tgcttaatgc gattgtccaa tcaccagtac cacaacaaac atctaatgct
     2341 ttcgtccctt ttctaacacc catgtctttc atgacgcgtt ttctccatac tttatgctgc
     2401 tcaaaactaa taatattatt taatctgtca tatttttttg aaatattttg aaaaacgcga
     2461 tgtacttgct ctttatttgc tttattgtca gccatgctta attacctcta ctttttaaat
     2521 aacttttttg gatatcgtgt aagtaatgct ttacttcact ttgattatat ttcttgaagt
     2581 atgatggata gtaatcagac atatcttcaa ataaataatt atatatttcc gactcatcaa
     2641 tattgatacc gaaatgagat aacgtaatat atgggaaaag tgtttcaatt tttactattg
     2701 cttgagaaat ttcataatca tttaaagctt gatgatgtaa tgaagatttc aattcattaa
     2761 tttcaacaat tgctttacta atttcatttt gaaatgataa atcattgatt tctgctagta
     2821 gcgtataaaa atgtgcacta attaaatctc caatcaaaat ggaatgttta gacaaatgat
     2881 tatatgtaat gtcatcaagg tgtctcattg atgtgtcaat tgtgaggcat gctactttgg
     2941 caacatctgg aatatcatat gaatcaagta acttacctaa ccgatgatta atattaatgg
     3001 attcatattc tgatacaccc tttaatcttt cttctatttg tctttccaat ttgctaacag
     3061 ttgtttccat gtctacacct cacgatatta tcactattca tattaacatt atatgtaaga
     3121 aattaaaatc ttttgaagca ttaagattac ttatcatttt taaatttcaa tttaaactaa
     3181 cagtaattta tgtagctttt gtaattctca taataacctt tacttcattt acattattca
     3241 tctttttaaa taacgtaaaa tactatagta gacatggtta ccttttaagt aaattcaacg
     3301 ctaacaatta atctcattat tcat
//
LOCUS       DAPSKH010000114         3289 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPSKH010000114 DAPSKH010000000
VERSION     DAPSKH010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3289
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.118"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            142..3051
                     /gene="sdrC"
                     /locus_tag="RPH49_002611"
     CDS             142..3051
                     /gene="sdrC"
                     /locus_tag="RPH49_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MSCRAMM family adhesin SdrC"
                     /protein_id="HDY5125720.1"
                     /translation="MNNKKTATNRKGMIPNRLNKFSIRKYSVGTASILVGTTLIFGLS
                     GHEAKAAEHTNGELNQSKNETTGTSENKTTEKVDSRQLKDNTQTATADQPKVTMSDSA
                     TVKETSSNMQSPQNATANQSTTQTSNVTTNDKSSTTYSNETDKSNLTQAKDVSATPKT
                     TTIKPRTLNRMAVNTVAAPQQGTNVNDKVHFSNIDIAIDKGHLNKDTGKTEFWATSSD
                     VLKLKANYTIDDSVKEGDTFTFKYGQYFRPGSVRLPAQNQNLYNAQGNIIAKGIYDSK
                     TNTTTYTFTNYVDQYTNVSGSFEQVSFAKRENATTDKTAYKMEVTLGNDKYSKDVIVD
                     YGNKKGQQLISSTNYINNEDLSRNMTVYVNQPKNKYTKETLVTNLTGYKFNPDAKNFK
                     IYEVTNQNQFVDSFTPDTSKLTDVTDKFKITYSNDNKTATVDLLNGQSSSDKQYIIQQ
                     VAYPDNSSTDNGKIDYTLETQNGKSSWSNSYSNVNGSSTANGDQKKYNLGDYVWEDTN
                     KDGKQDANEKGIKGVYVILKDSNGKELDRTTTDENGKYQFTGLSNGTYSVEFSTPAGY
                     TPTTANAGTDDAVDSDGLTTTGVIKDADNMTLDSGFYKTPKYSLGDYVWYDSNKDGKQ
                     DSTEKGIKGVKVTLQNEKGEVIGTTETDENGKYRFDNLDSGKYKVIFEKPAGLTQTGT
                     NTTEDDKDADGGEVDVTITDHDDFTLDNGYYEEETSDSDSDSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSYSDSDSYSDSDSDSDSDSDSDSDS
                     DSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDRDSDSDR
                     DSDSYSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDSDNDSDSDAGKHT
                     PAKPMSTVKDQHKTAKALPETGSENNNSNNGTLFGGLFAALGSLLLFGRRKKQNK"
BASE COUNT         1325 a          513 c          581 g          870 t
ORIGIN      
        1 agcaaataac attgtaaaat aaagaaaaat aattaaagta ttgcacttta ttgaaattta
       61 tattacgata gtaatgcaga aatttatata tgcaaaatat tatatttatc aaattttgat
      121 attttaaagg agtattatta aatgaataat aaaaagacag caacaaatag aaaaggcatg
      181 ataccaaatc gattaaacaa attttcgata agaaagtatt ctgtaggtac tgcttcaatt
      241 ttagtaggga caacattgat ttttgggtta agtggtcatg aagctaaagc ggcagaacat
      301 acgaatggag aattaaatca atcaaaaaat gaaacgacag gcacaagtga gaataaaaca
      361 actgaaaaag ttgatagtcg tcaactaaaa gacaatacgc aaactgcaac tgcagatcag
      421 cctaaagtga caatgagtga tagtgcaaca gttaaagaaa ctagtagtaa catgcaatca
      481 ccacaaaacg ctacagctaa tcaatctact acacaaacta gcaatgtaac aacaaatgat
      541 aaatcatcaa ctacatatag taatgaaact gataaaagta atttaacaca ggctaaagat
      601 gtttcagcta ctcctaaaac aacgactatt aaaccaagaa cattaaaccg tatggctgtg
      661 aacacagtag cagcaccaca acaaggtaca aatgttaatg ataaagttca tttttcaaat
      721 attgatattg ctattgataa aggacactta aataaagata ctggcaaaac tgaattttgg
      781 gcaacttcaa gtgatgtttt aaaattaaaa gcgaattaca caatcgatga ttctgttaaa
      841 gagggcgata catttacttt taaatatggt caatatttcc gtccaggttc tgtaagatta
      901 cctgcacaaa atcaaaattt atataatgcc caaggtaata ttattgcaaa aggtatttac
      961 gatagtaaaa caaatacaac aacgtatact tttacgaatt atgtagatca atatacaaat
     1021 gttagcggta gctttgaaca agtttcattc gccaaacgtg aaaatgcaac aactgataaa
     1081 actgcttata aaatggaagt tacattagga aacgataaat atagtaaaga cgtcattgtc
     1141 gattatggta ataaaaaagg acaacaactc atttcaagta caaactatat taacaatgaa
     1201 gatttatcac gtaatatgac tgtttatgta aaccaaccta aaaataaata tacaaaagaa
     1261 acattagtaa caaatttaac tggttataaa tttaatccag atgctaaaaa ctttaaaatt
     1321 tatgaagtaa ctaaccaaaa tcagtttgtg gatagtttca ccccagatac ttcaaaactt
     1381 acagatgtca ctgataaatt taaaattaca tacagtaatg ataataagac ggcgacagta
     1441 gatttattga atggtcaatc tagtagtgat aaacaataca tcattcaaca agttgcttat
     1501 ccagataata gttcaacaga taatgggaaa attgattata ctttagaaac acaaaatgga
     1561 aaaagtagtt ggtcaaacag ttattcaaat gtgaatggct catcaactgc taatggcgac
     1621 caaaagaaat ataatctagg tgactatgta tgggaagata caaataaaga tggtaaacaa
     1681 gatgccaatg aaaaagggat taaaggtgtt tatgtcattc ttaaagatag taacggtaaa
     1741 gaattagatc gtacgacaac agatgaaaat ggtaaatatc agttcactgg tttaagcaat
     1801 ggaacttata gtgtagagtt ttcaacacca gccggttata caccgacaac tgcaaatgca
     1861 ggtacagatg atgctgtaga ttctgatgga ctaactacaa caggtgtcat taaagacgct
     1921 gacaacatga cattagatag tggattctac aaaacgccaa aatatagttt aggtgattat
     1981 gtttggtacg acagtaataa agatggtaaa caagattcga ctgaaaaagg aattaaaggt
     2041 gttaaagtta ctttgcaaaa cgaaaaaggc gaagtaattg gtacaactga aacagatgaa
     2101 aatggtaaat accgctttga taatttagat agtggtaaat acaaagttat ctttgaaaaa
     2161 cctgctggct taactcaaac aggtacaaat acaactgaag atgataaaga tgccgatggt
     2221 ggcgaagttg atgtaacaat tacggatcat gatgatttca cacttgataa tggttactac
     2281 gaagaagaaa catcagatag cgactcagat agcgactcag attcggacag cgactcagac
     2341 tcagatagcg actcagattc ggacagcgat tcagactcag atagcgactc agattcagac
     2401 agcgattcag actcagatag cgactcagac tcagatagcg actcagattc ggacagcgat
     2461 tcatactcag atagcgactc atactcagat agcgactcag attcagacag cgactcagat
     2521 tcagatagcg attcagattc agacagcgac tcagactcag acagtgattc agattcagat
     2581 agcgactcag attcagatag cgattcagat tcagatagcg actcagattc agatagcgat
     2641 tcagattcag acagcgactc agattcagat agcgactcag actcagacag agattcagat
     2701 tcagacagag attcagattc atatagcgac tcagactcag atagcgactc agactcggat
     2761 agcgattcag attcagacag cgactcagat tcagacagcg actcagattc agacagcgac
     2821 tcagattcag atagcgattc ggactcagac aacgattcag attcagatgc aggtaaacat
     2881 actccggcta aaccaatgag tacggttaaa gatcagcata aaacagctaa agcattacca
     2941 gaaacaggta gtgaaaataa taattcaaat aatggcacat tattcggtgg attattcgcg
     3001 gcattaggat cattattgtt attcggtcgt cgtaaaaaac aaaataaata atatgattaa
     3061 cttaaccagg tccatgtggc ctggtttttt ctgtttagaa attcccagat ataaaacaaa
     3121 aaatctttaa ggaatagata caatttaatt tgttacagaa atgtaattgt ctatgaatta
     3181 gaaaagctaa gatattaatt ttaagggcaa ataatactat tttttatgat aattaaataa
     3241 agattacaaa actcataaaa atttttattt aaacacgaat gttaaataa
//
LOCUS       DAPSKH010000115         3229 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPSKH010000115 DAPSKH010000000
VERSION     DAPSKH010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3229
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.119"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(88..531)
                     /locus_tag="RPH49_002612"
     CDS             complement(88..531)
                     /locus_tag="RPH49_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125721.1"
                     /translation="MRTLNKDEHNYIKQIANIHETLLSQVESNYKCTKLSIALRYEMI
                     CSRLEHTNDKIYIYENEGQLIAFIWGHFSNEKSMVNTELLYVEPQFRKLGIATQLKIA
                     LEKWAKTMNAKRISSTIHKSNLPMISLNKDLGYQVSHVKMYKDID"
     gene            658..1347
                     /locus_tag="RPH49_002613"
     CDS             658..1347
                     /locus_tag="RPH49_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 family protein"
                     /protein_id="HDY5125722.1"
                     /translation="MKSTAQLTKENNVKSLRLSNTDREIFENYMTYMRSDFRVNPHDT
                     ELIINRILKQLLSAEQHGLLALDFFNHDPKAHAIKELKAMPNETFKNIFKYIYQHIVL
                     LIGIVSFLKGFLGFFMEKSGSNLYFVSFPFSVVVGFFIVFLFIWFSFKTIQLQCFNNS
                     NWIWIFTYLAIILLIVGFFYVFFIPQSLLAFGPYIQVSNWVFIIFSFIVMPIGLRIER
                     NISKKHSHTFL"
     gene            complement(1446..1934)
                     /locus_tag="RPH49_002614"
     CDS             complement(1446..1934)
                     /locus_tag="RPH49_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF456 domain-containing protein"
                     /protein_id="HDY5125723.1"
                     /translation="MTIILWLLIIAAFMLAFVGLIKPIIPSVLVLWVGFLIYQFGFHN
                     QHLSWVFYVSMALLTILILCADFLANKYFVNRFGGSKFGEYAALIGVVIGCFVLPPFG
                     IIIIPFILVFIVELIQGYSFERAVKVSIGSIVAFLTSSIAQAIIMFIMIVWFFIDALL
                     IN"
     gene            complement(1931..3151)
                     /locus_tag="RPH49_002615"
     CDS             complement(1931..3151)
                     /locus_tag="RPH49_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HDY5125724.1"
                     /translation="MDMFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGM
                     TTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTI
                     WLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPF
                     IGAQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKD
                     KTLLLPFIAFILLHIGQWMYTMNMPLFVTDYLKENEQHVGYLASLCAGLEVPFMIILG
                     VSSSRLQTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQ
                     DILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFF
                     TKNQKITKEDVIST"
BASE COUNT         1174 a          544 c          428 g         1083 t
ORIGIN      
        1 actgatgatt aatttcttca tataaaactc cttaacgtca ttaaatcttt tttaatttta
       61 acatgaatta gcaacataat cctaattcta atcaatatct ttatacattt tcacatgact
      121 cacttgataa cctaaatctt tattcaaaga tatcattggt aaattacttt tatgaattgt
      181 actgcttatt cgctttgcat tcatagtttt tgcccatttt tcaagcgcaa tcttcagttg
      241 cgtagctatt cccagtttgc gaaattgtgg ttcaacatat agcagttcag tgttaaccat
      301 acttttttca ttactaaaat gtccccaaat aaacgctatt aattgacctt cattttcata
      361 tatataaatt ttatcatttg tatgttctaa tcttgaacat atcatctcgt acctaagagc
      421 aatactcagt ttagtacatt tatagttgga ttctacttgc gacaataatg tctcatgtat
      481 attagctatt tgcttgatat aattatgttc atctttatta agtgtcctca ttttcctctc
      541 caatattaat cgttatattt atgcgtttaa tatgatatga ttgaccttat taatactata
      601 aaatcatttc cattttaatt tggaattaaa catttttaaa ggagcgctta attaacaatg
      661 aaaagtactg cgcaattaac aaaagaaaat aatgttaaat cattaagatt aagcaatact
      721 gatagagaaa tcttcgagaa ttatatgact tatatgcgct ctgactttcg cgtcaatcct
      781 catgatacag agttaattat taaccgtata cttaaacaat tattaagcgc agaacaacat
      841 ggtttattag ccttagattt tttcaatcac gatccaaaag cacatgcaat aaaagaacta
      901 aaagcgatgc ctaatgaaac atttaaaaat atttttaaat atatatatca gcacatcgtt
      961 ctattaattg ggattgttag ttttctcaaa ggatttttag gatttttcat ggaaaaaagt
     1021 ggaagtaatt tatattttgt ttcgttcccg ttttcagtag tcgtcggatt ctttattgtc
     1081 tttttattta tatggtttag ttttaaaaca atacaattgc agtgttttaa caattcaaat
     1141 tggatatgga tattcaccta tttagcaatc attctactaa ttgtaggatt tttctatgta
     1201 ttctttattc cacaatcatt acttgccttt ggaccatata ttcaggtaag caattgggta
     1261 tttattatat tttcatttat tgttatgcct attggattac gcattgaaag aaatatttcg
     1321 aaaaaacatt ctcatacatt tttataaact aaaagcttat tacatcatat gcgaatttgg
     1381 tactgttcat gataaaatca caaaattaca gttaccgaaa aacatatttt gcaataagct
     1441 ttttattaat taatcaataa agcatctata aagaaccata caatcattat aaacataatg
     1501 attgcttgag ctatactact tgttaaaaat gctacgattg aacctatact tactttaact
     1561 gctctttcaa atgaatagcc ttgtattaat tcaactatga ataccaaaat aaaaggtata
     1621 ataataattc caaatggcgg taaaacaaaa catccaataa ccacaccaat taaagctgca
     1681 tactctccaa acttagaacc accgaagcga ttcacaaaat atttattagc taaaaagtcc
     1741 gcacataaaa ttaatattgt tagcaatgcc atagatacat aaaacaccca tgataaatgc
     1801 tgattatgaa agccaaattg atagattaga aagccaaccc ataatactaa aacagaagga
     1861 ataatcggct taatcaaccc aacaaatgct aacatgaagg cagcaatgat aagtagccat
     1921 aaaataattg tcatgttgat atcacatcct cttttgtaat tttttgattt ttagtaaaga
     1981 atataagtat catacctaac atgattgatg ctgctgatac aaaaaataca ttttccaaac
     2041 ctacccagtg actcatagca ccacctaata agttaccgcc taactgtcca ataaccattg
     2101 cattagaaaa tagtgttgag gcgtatcctg ggaaatctgg taagatatct tgaaaataac
     2161 taataccaat tcctaaaaga accgctaaga aaatagctaa aaacacctgt cctgctaaca
     2221 tcatatagaa gtttttaaat accccaatgc tgaagtagaa taaaccacca aatatcgctc
     2281 cataaatcaa caatgttcga gtctgtaatc tagatgatga aacgccaaga atgatcataa
     2341 atggcacttc taaaccagca cataaactag ctaaataacc gacatgttgc tcattttctt
     2401 ttaaataatc agtaacaaat aaaggcatat tcatcgtata catccattgt ccaatgtgta
     2461 ataaaataaa tgcaataaat ggtaataaaa gtgttttgtc tttaaacata ttaggagcaa
     2521 ttttttcaac atgttgttgc gtactaatag ggtgtttaat gtttaaatcc ttatagaaaa
     2581 acacttgaag tactaaagta aataaaatga tacttattgt tccaccaaac aatccagcat
     2641 agccttttaa tccgattaat tgggcaccaa taaatggacc aaataaaaag cccaatgaga
     2701 acattgaacg taatactgtg ttggcaaatt gagctctatc tttagagctt gaaacattga
     2761 tagattctct agcagatgcg taaagttggg gcattgctgg tgcaaataat ccttggaaaa
     2821 tcgcatatag taatatgaat aaccagattg tatctacaaa aaagtatatt gaaaaaccaa
     2881 gcgcacccat taataatgcg agaataataa taatttttct attaaagtga tgcgtatccg
     2941 aaaatctagc aataattgaa tttactgtaa actggctaat cgctgcagat gctagaagta
     3001 atccatactg atttgttgtc atacctaaat ctttagttgc aaaaagaaca agatatggga
     3061 ccgtaaccgc aatacccata cctagtagaa acatattagc aacaaagagt ttataattct
     3121 ttatttgtaa taacgctgca aacatatcca taaccccact tcttagagcc ccttttaatt
     3181 tattaattag gggctcttat gcagttggtg cgttagcaat caactgtaa
//
LOCUS       DAPSKH010000116         3086 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPSKH010000116 DAPSKH010000000
VERSION     DAPSKH010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3086
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.120"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..557
                     /locus_tag="RPH49_002616"
     CDS             <1..557
                     /locus_tag="RPH49_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HDY5125725.1"
                     /translation="ALSNVAWFWHTSYSHRTEQARIRLYIPLNERISADDYRNYTKVL
                     ANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKGYKQSNDS
                     PNIKGYTRRDSAYWRDIAFGVSEGERNSTLASITGYLLRRYVDPNLVYGLVSAWASVC
                     KPPINQSEVNNTFKSILKKDSKYS"
     gene            574..2043
                     /locus_tag="RPH49_002617"
     CDS             574..2043
                     /locus_tag="RPH49_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence-associated protein E"
                     /protein_id="HDY5125726.1"
                     /translation="MEDVTNEEVFEMIDSRTGVLNANDWKSQLRRSATTQALKKTTTN
                     AEIILCNDESLKGLVQYDAFEKVTKLKRLPYWRSKGDANYYWADIDTTHVISHIDKLY
                     NVQFSRDLIDTVIEKEAYQNRFHPIKSMIESKSWDGIKRIETLFIDYLGAEDNHYNRE
                     VTKKWMMGAVARIYQPGIKYDSMIILYGGQGVGKSTAVSKLGGHWYNQSIKTFKGDEV
                     YKKLQGSWICEIEELSAFQKSTIEDIKGFISAIVDIYRASYGKRTERHPRQCVFVGTT
                     NNYEFLKDQTGNRRFFPITTDKNKATKSPFDDLTPVVVQQMFAEAKVYFDENPTDKAL
                     LLDKEASEMALKVQEAHSEKDALVGEIEEFLERPIPSDYWYRTLEEKRVSAHDVIDQD
                     YIKLYGDGKLIELPNAKPGAYVWRDKVCSMEIWKVMMKRDDQPQQHHLRKIDKALRNT
                     SYCGQSKSRHRFGEGIGRQYGFGINLISYYQGLKSKEQK"
     gene            2329..2691
                     /locus_tag="RPH49_002618"
     CDS             2329..2691
                     /locus_tag="RPH49_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012990923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125727.1"
                     /translation="MNKNQLKSEILEYIKAHVGTSFVEIERVFEENNFDYKGDGAYTS
                     GQHPNVVFWVGWNQEAFDVIAELKKDGHIEMDICEPIVYMVDGKGLDLPIVRSKNIKT
                     DHWLPVTFTISKKETECV"
     gene            2693..2977
                     /locus_tag="RPH49_002619"
     CDS             2693..2977
                     /locus_tag="RPH49_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125728.1"
                     /translation="MNDKEKIYNQLHHDAPIQIIPAPENLFVEYIEADEVWYSPVVCM
                     ALSKAHNINFYDSDDVGCIDKAATCSIKKFNPETGEFEQFSKMAQKEITQ"
     gene            2974..>3086
                     /locus_tag="RPH49_002620"
     CDS             2974..>3086
                     /locus_tag="RPH49_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125729.1"
                     /translation="MNIETVVNEFETRAGTLLRYYTGLLESSRETHFAFKI"
BASE COUNT         1108 a          414 c          670 g          894 t
ORIGIN      
        1 cagctttaag caatgttgca tggttttggc acacaagtta ctcgcacaga actgaacaag
       61 ctagaatacg cctgtatatc cctctaaatg agcgaataag tgcagatgat tatcgtaatt
      121 atacaaaagt attagcgaat aaaattggcc acaaagttga tgaaggttca tatcagccaa
      181 gtagatgttt tgcgttacca gttattcaaa aaggacacat atttattaaa cgagtgaatg
      241 actgtccgat tatgaatgtt gatatgctcg agcagtggtc aaaggggtat aaacaatcaa
      301 atgatagtcc taatatcaaa gggtacacac gacgtgatag tgcgtattgg cgagatatag
      361 cttttggtgt aagtgaggga gagcgcaatt caacattggc ttcaattaca ggttatcttt
      421 tgcgtaggta tgtagatcca aacttagttt atgggttagt gagtgcgtgg gcaagtgtat
      481 gcaaaccacc tattaatcaa agtgaagtaa acaatacttt taaaagtatt ttgaaaaaag
      541 atagtaaata cagttagaaa tggaggtttt tgtttggaag atgttacaaa cgaagaagta
      601 tttgaaatga ttgatagcag aaccggtgtt ttaaatgcta atgattggaa aagtcaatta
      661 aggcgctctg ctactacaca agcattgaaa aaaacgacta caaatgctga aatcatattg
      721 tgtaatgatg agagtttaaa agggctagta caatatgacg cttttgaaaa agtaaccaag
      781 ctgaaacgtc taccgtattg gaggtcaaaa ggggatgcga attattattg ggctgatata
      841 gataccacac atgtgatttc acatattgat aaattgtata atgtgcagtt tagccgcgat
      901 cttattgata ctgtaattga aaaggaagca tatcaaaata gattccaccc tattaaatcg
      961 atgattgaat ctaaatcatg ggatggaatc aaaagaattg aaacgctctt cattgattat
     1021 ttaggtgctg aagataatca ctacaatcga gaagttacaa agaaatggat gatgggtgca
     1081 gttgctagaa tctatcagcc aggtattaaa tatgattcca tgattatttt atatggtggt
     1141 caaggtgttg ggaaatctac ggcagtgagt aaattgggag gtcattggta taaccaaagt
     1201 attaaaacgt ttaaaggtga tgaggtctat aagaaattgc agggttcttg gatatgtgaa
     1261 attgaagaac tgtcggcatt tcaaaagtct actattgaag atattaaggg ttttataagt
     1321 gccattgtag atatttatag agcttcgtat ggtaaacgca cagagcgtca tcctagacag
     1381 tgtgtgtttg tagggacaac caataactat gagtttttaa aagaccaaac aggcaatcgt
     1441 cgttttttcc ctattacgac agataaaaat aaagcaacta aaagcccatt tgacgatcta
     1501 acaccagttg ttgtgcaaca aatgtttgcc gaagctaaag tatattttga tgagaatccg
     1561 acggataaag cattgttgct agataaagaa gcgagtgaaa tggctttaaa agtccaagaa
     1621 gctcattctg aaaaagatgc tttagttgga gaaatagaag aatttcttga acgtcctatt
     1681 ccgtcagact attggtatag aacgttagaa gaaaaaagag tgtctgcgca tgatgttata
     1741 gaccaagact atattaaatt atatggtgat ggtaaattga ttgaattacc gaatgcaaaa
     1801 ccaggtgctt atgtatggcg tgacaaggta tgtagcatgg aaatttggaa agtgatgatg
     1861 aaacgagatg accaaccaca acaacaccat ttaagaaaaa ttgataaagc gttaagaaat
     1921 acaagttatt gtgggcaaag taagtcgcgt catagatttg gtgaaggtat tggtagacaa
     1981 tatggttttg gtattaattt aatatcctat tatcaaggtt taaaaagcaa agaacaaaaa
     2041 taacgggaca acgggacgat tatgggacaa tggtaggaca ccttcaatct cttgtggcag
     2101 tatgcattat gttatgtttg tccctgtgtc ccgcaacttt taccctaaac ttttaaagta
     2161 atatatacac attaaaaaat atataagtgt aggcataaaa cagtgggaca atgggacaga
     2221 taactttaat ccattgggag agtggtgttt gagcattgtc ctgacaatgt cctgaaacat
     2281 attgaaaata gcgaaatggg acacctatca aaaattagga ggaagaaaat gaataaaaat
     2341 caattaaagt cagaaatttt agaatatata aaggcgcatg ttggtacatc atttgtagaa
     2401 atagaacgtg tatttgaaga aaataacttt gattataaag gtgacggcgc atatacaagt
     2461 ggtcaacatc ccaatgttgt gttttgggtt gggtggaatc aagaagcgtt tgatgttatc
     2521 gctgaactta aaaaagatgg acatattgag atggatattt gtgagccaat tgtttatatg
     2581 gttgatggta aaggtttgga tttgcctatt gtaaggtcga aaaacattaa aacagatcat
     2641 tggctacctg tcacgtttac tattagtaag aaagaaacgg agtgtgtcta atatgaatga
     2701 caaagagaaa atttataatc aacttcatca tgatgcacca attcaaatta taccagcacc
     2761 cgaaaattta tttgtcgaat atatagaagc tgatgaagta tggtattcac cagttgtatg
     2821 tatggcttta agtaaagcgc ataatattaa tttttatgac agtgatgatg tggggtgcat
     2881 tgataaagca gccacatgta gcattaaaaa atttaatcct gagacaggtg agtttgaaca
     2941 attcagcaaa atggctcaaa aggagataac gcaatgaaca tagaaactgt agtaaatgaa
     3001 tttgaaacac gagcaggcac gttattaagg tattacacag gtttattaga aagtagtaga
     3061 gaaacgcatt tcgctttcaa aatata
//
LOCUS       DAPSKH010000117         3006 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPSKH010000117 DAPSKH010000000
VERSION     DAPSKH010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3006
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.121"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..473
                     /locus_tag="RPH49_002621"
     CDS             <1..473
                     /locus_tag="RPH49_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001667297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HDY5125730.1"
                     /translation="NERISADDYRNYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGH
                     IFIKRVNDCPIMNADMLEQWSKEFEQSNASPNIKGYTRHDSAYWRELSFGTTEGNRNN
                     ALASLVGHLLRCRVNDYIVYSYALLWGQFACKPPMKEQEINATFQSILNKHYNN"
     gene            487..2187
                     /locus_tag="RPH49_002622"
     CDS             487..2187
                     /locus_tag="RPH49_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001611933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HDY5125731.1"
                     /translation="METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQL
                     IPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISD
                     SRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEV
                     MKDSNIKLFSNDKGFQKLIDSFQSKGTLEGYSKKVFGQIKDLPMVMVMLYASLGSVLL
                     REFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFP
                     MFKDDTRNTHPKFVTSATYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMA
                     DEKAGVSARVVTLQDQPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFE
                     SYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNK
                     TIDKPKQLLEELLQYLDANRNNIAGDGYSSVKNGDTKAIYKRDYLCILGQTVYDKLGH
                     EMQTITGQWDKKGYLITSKDRIQKEVRFNSQKNRGYAIKDEIIKELGFDFSNSHNPYN
                     "
     gene            2517..2897
                     /locus_tag="RPH49_002623"
     CDS             2517..2897
                     /locus_tag="RPH49_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125732.1"
                     /translation="MDKEQLKKYIYDYVKEYKEIPIYQLEDLFKEINHDYIGRTSITH
                     DKDENVVFWSGWNKITMFALIELVKSEQLDLVYRGSFVMRYLLDGRVPNLPLAICYPE
                     DGQQTDVLSWVPMVLRINKEEKIK"
     gene            2894..>3006
                     /locus_tag="RPH49_002624"
     CDS             2894..>3006
                     /locus_tag="RPH49_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012990921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125733.1"
                     /translation="MNIETIVNEFETRAGTLLRYYTGLLEHSKVQPYCFKL"
BASE COUNT         1142 a          434 c          563 g          867 t
ORIGIN      
        1 taaatgagcg aataagtgca gatgattatc gtaattatac aaaagtatta gcgaataaaa
       61 ttggccacaa agttgatgaa ggttcatatc agccaagtag atgttttgcg ttaccagtta
      121 ttcaaaaagg acacatattt attaagcgag tgaatgactg tccaattatg aatgctgata
      181 tgctcgaaca gtggtcaaag gagtttgaac aatcaaatgc tagtcctaat atcaaaggat
      241 acacgcgaca tgatagtgcg tactggcgtg agttaagctt tggaacaacc gaaggcaatc
      301 gtaacaatgc actagctagc ttagttgggc atttattaag atgtcgcgtc aatgattata
      361 ttgtgtattc atatgcttta ttatgggggc aattcgcatg taaaccacct atgaaagaac
      421 aagaaatcaa cgccactttt caatcgatat taaataaaca ctataacaat tagaaagggg
      481 ctttgtatgg aaacaggtaa aagtgatgta cttgataaaa ttgaaaaaat taataaaaaa
      541 gatagtgcct tacaagaaat tataccgaaa ggctatgaaa ttgaacatca tcaatgcggt
      601 gttgccttat atcaacttat accaagtaaa aaagaaggtg aaccagataa aaaggttttt
      661 atcacaaata caatccctca aattactgaa cgctttgaag atattgagag taacgaagtc
      721 agctttaata tgcttttcta tgacaataaa acgcctgtaa atatagcagt gagcgccgaa
      781 gaaatttcag atagtcgtca actcttgaaa ttggttaata aaaagctaga tgtaacatcg
      841 tcgacatcta ctaaacttgt tgactatatt aatgtatcta aacggtataa tccaccatta
      901 aatgttaaag ttgcaacgcg cttgggacat gtgaaaggtt attttattta tccttatcaa
      961 gaagtgatga aagacagcaa tatcaagttg tttagtaatg ataaaggatt tcaaaagtta
     1021 atagactctt ttcaaagcaa aggaacatta gaaggttact ctaaaaaagt gttcggtcaa
     1081 ataaaagatc taccaatggt aatggttatg ttatatgcat ctttaggctc agttttatta
     1141 agagaatttg gattacaacc ctttattgta gaaatatcag gtagtacatc cacaggtaaa
     1201 acattcacac tcaacttagt atcaagtgtt tggggaacca gtgaccttat tacgacatgg
     1261 agttctactc aaaatagtat tgaatcaatg gcatcatttt tgaactcatt tccaatgttt
     1321 aaagatgata cacgtaatac acatcctaag tttgttacca gtgccacata taacttttct
     1381 agtggcgaaa gcaaatcaag aagtaatatt aatttaacgc taaatgctaa aaaagaatgg
     1441 cgaaatattt taatttctac tggtgaatca tctatcgcaa atatggctga tgaaaaagcg
     1501 ggtgtatcag cacgtgtagt tacactacaa gatcaaccat atccagataa ttttgatttt
     1561 accacattag acaaatcgtt tagggagaac tatggaacgt tagggttggc atttattaaa
     1621 caatatgagt ctaaaaaaga cgtgtataag aacgcttttg aaagctatca acggtatttt
     1681 aatcaaaaag gtagtaatga aatcatgcaa cgtttaggac gtgcctttgc gttactacaa
     1741 gttaccggtg aggttttgaa tgatattgat ggatttgaac atgaccattt taaaattatt
     1801 gaacaagcct atgacagcat ggttaaaaac aataagacga ttgataaacc taagcaactg
     1861 ttagaggaac tattacaata tttagatgca aatagaaata atatcgctgg tgatggatat
     1921 agttcagtca aaaatggtga caccaaagct atatataaac gtgattattt atgtatatta
     1981 ggtcaaactg tatacgacaa gttaggtcat gaaatgcaaa ctatcacagg acaatgggac
     2041 aaaaagggct atttaataac tagtaaagac agaatacaaa aagaagttag atttaactct
     2101 caaaagaata gagggtatgc cattaaagat gagattataa aagaattagg gtttgatttt
     2161 tctaattcac ataatccata taattaaaaa gtccccaaag tctccaaaca gtccccacta
     2221 aaaaggaatg attggggact taataaacac tattaccgca atactttaga gagattagtc
     2281 cccaaagtcc ccaataaaaa aacagtgttt atataaaatg atcaaaaaga acattgagtg
     2341 taatttaata tatagctacc atcgtttata aatatggtga ctatggggac tatttctaac
     2401 aaaatcagtt atatcaacgg gtgaaacagt ccccaataaa taattagggt ggggactcac
     2461 tggggactag tcccctacta aaataaaaaa catcaaatta atgctggagg ttacacatgg
     2521 ataaagaaca acttaaaaaa tatatatacg attatgtaaa agaatataag gagataccga
     2581 tatatcagtt agaagatttg tttaaagaaa taaatcacga ctatataggg agaactagta
     2641 tcacacacga taaggatgag aatgtagtgt tttggagtgg atggaacaaa attacaatgt
     2701 ttgcgctgat tgaattagtt aaaagtgaac aacttgattt agtgtataga ggtagttttg
     2761 taatgcgtta tttgttggat ggtagagttc ctaacttacc attagctatt tgttatccag
     2821 aagatggaca acaaactgac gtgctctcat gggtgcctat ggtgttaaga ataaataaag
     2881 aggagaaaat caaatgaaca tagaaactat cgtaaatgaa tttgagacgc gagcaggcac
     2941 gctattaagg tactacacgg gattattaga acatagtaaa gtacaaccgt attgctttaa
     3001 gttata
//
LOCUS       DAPSKH010000118         2907 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPSKH010000118 DAPSKH010000000
VERSION     DAPSKH010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2907
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.122"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            364..2514
                     /locus_tag="RPH49_002625"
     CDS             364..2514
                     /locus_tag="RPH49_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125734.1"
                     /translation="MAKSCLHILTNNEYATTRCQDGIVLFWPIDGEIELQKFRKSKII
                     EDDIYIINHLDVFSIKNNKKTIMLYLSSDWFAELGFTFFNYHYTAKLIKSSYNLKCLL
                     LKLTYRYLDNQPLNDADIRKLQDIIKIIAKEASMDKKIAQNQYRYAYYGDLRDELEYI
                     YQNVNQRLTLKSVADKLFVSKSNLSSQFHLLMGMGFKKYIDTLKIGKSIEILLTTDST
                     ISNISEHLGFSSSSTYSKMFKSYMDITPNEYRNLSKFNKCIMLNPEPLVGGMAQEVKE
                     VILNYIDHYKNHLTDVIHIDEDKFEIPKLFQTVVQINTYTEMKLVFLEGIFKTLLNKN
                     SQVVFFIMPSILKSKNTMSEEEKFTIIKTIIESDLKIAFNINDIETTYYVEEAFMNVI
                     RQLSPNEINHHNNYEVHFVFDLSLMEIRTIYRMILKLHNIMLNVKLGLNITCLFDKPS
                     VFKSLVSQIKRLKFNSLIIDNANLSSPYLMGESDELLLKNILHFKNLKKVINELDIEQ
                     EKLIFLNVENHKLLNNKERDLSNSAPLIYKTLSALYHNFDGFGLNIFDNHQTFNAMHL
                     YDKNGFKTTLGLILEKFIEYVSKPKYENSYYSIFDIENYHCLVIYDWRVIESETIMSN
                     FEDSQVYINFKNNVLNDKYLIVIETLDENSGNINHLISKELRDKYEWNPSLLSKIDNY
                     LKPAIEIKEHNFSNNSLNINVTFNALYIIKIGKK"
     gene            2660..>2907
                     /gene="sarX"
                     /locus_tag="RPH49_002626"
     CDS             2660..>2907
                     /gene="sarX"
                     /locus_tag="RPH49_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SarX"
                     /protein_id="HDY5125735.1"
                     /translation="MNTEKLETLLGFYKQYKALSEYIDKKYKLSLNDLAVLDLTMKYC
                     KDEKVLMQSFLKTAMDELDLSRTKLLVSIRRLIEKERL"
BASE COUNT         1145 a          320 c          447 g          995 t
ORIGIN      
        1 taatgttagt ttgagctcat ctcaaaagta gaatgtgatt taaataagtg tttattttta
       61 aattgaaaat gaatgtaagg ctaacaaaag ataatagtaa tacgttgtag atgtggtcat
      121 ttaaaattat tttgaaaatg ctaaaaagta gtgcgttttc aattagatag tttaattaaa
      181 ctgactacat ctatttttgt aatgtttaaa tgattgatat ataagtttaa aaattaacca
      241 ttatatagtt ttatttattt ttgatttggt attcgtattg tgttaaattt acgtttaatt
      301 aaataagtta aatattatag ggaatgataa aagtggtatt taaatataga aagaggtaaa
      361 gttatggcaa aatcatgctt gcatatactt actaataatg aatatgcgac aacgcgttgc
      421 caagatggca tagtcttatt ttggccaatt gacggggaaa tcgaactaca aaaatttcgt
      481 aaaagtaaaa taattgaaga tgatatatat atcattaatc atctggatgt atttagtatt
      541 aagaataata aaaaaacgat catgttgtat ttgagtagcg attggtttgc ggaattaggc
      601 tttactttct ttaattatca ctatacagca aagttaatta aatcatccta taatttgaaa
      661 tgcttattat taaaattgac atatcgatac cttgataatc agcctcttaa tgacgctgat
      721 attagaaaat tacaggatat tattaaaatc attgcaaaag aagcaagtat ggataaaaag
      781 attgcgcaaa atcaatatcg ttatgcttat tatggtgatt tgcgagatga gctcgaatat
      841 atttatcaaa atgtaaatca acgattgaca ttaaaaagtg tcgctgataa attatttgtt
      901 tcaaagtcaa atctgtcttc gcaattccac ttacttatgg gcatgggttt taaaaaatat
      961 attgatactt tgaaaattgg taaatccata gagattctac ttactacaga tagtactatt
     1021 agcaatataa gtgaacattt aggatttagc agcagctcaa cgtactctaa aatgtttaaa
     1081 agttatatgg atataacacc gaatgaatat cgtaatttat caaaatttaa taaatgtata
     1141 atgcttaatc cagagccact tgtaggcggt atggcccaag aagtaaaaga agtcatattg
     1201 aattatattg atcattataa aaatcaccta actgatgtta tacatattga cgaagacaaa
     1261 tttgaaatac ctaagttatt tcaaacggtt gttcaaatta atacttatac agaaatgaaa
     1321 cttgttttct tagaaggaat ttttaaaacc ttattgaaca agaacagcca agttgtcttt
     1381 ttcatcatgc catcgatttt aaaaagtaaa aataccatgt ccgaagaaga aaagtttaca
     1441 atcattaaaa ccataattga aagtgattta aagatagcat ttaatataaa tgatattgaa
     1501 acgacttatt atgttgaaga agcttttatg aatgttatta gacaattatc tccaaacgaa
     1561 ataaatcatc ataataatta cgaagtgcat tttgtttttg atttatcatt gatggaaatt
     1621 aggacaattt accgtatgat tttaaaacta cataacatca tgttaaatgt gaaattagga
     1681 ttgaatatta cctgtttatt tgataaacct tcagttttta aatcactagt atcacaaata
     1741 aagcgactta aattcaattc gttaataata gataatgcaa atttaagtag cccttatttg
     1801 atgggggaaa gtgatgagtt actattgaaa aatattttgc attttaaaaa tttaaaaaaa
     1861 gttattaacg aattggatat agaacaagaa aagctgattt ttctaaatgt tgaaaatcat
     1921 aaactgctta ataataaaga acgagattta agtaatagtg ctccattaat ttataagaca
     1981 ttaagtgcgc tgtatcataa ctttgatggt tttggattaa acatttttga taatcatcaa
     2041 acatttaatg cgatgcatct atatgataaa aatggattta aaacaacact aggtcttata
     2101 ttagaaaagt ttatcgaata tgtctcgaaa ccaaaatacg aaaacagtta ttattctatt
     2161 tttgatatag agaattatca ttgcctggtt atttatgatt ggcgagtgat tgagagcgag
     2221 acaattatga gcaattttga ggatagtcaa gtttatataa atttcaaaaa taatgtttta
     2281 aacgataaat atctaattgt aatagaaacg ttagatgaaa atagtgggaa cattaatcat
     2341 ttgatttcta aagaattaag agataaatat gaatggaacc ccagtttact ctctaaaatt
     2401 gacaactacc ttaaaccagc aatcgagatt aaagagcata actttagtaa taattcctta
     2461 aacattaacg ttacttttaa tgcgttatac ataattaaaa taggaaaaaa ataacacctt
     2521 gatatgtatt gcaaaattta atttgcattt gttggtaatt ttgacaacgt attaaaaaca
     2581 aatgagaaag acaatggcag aaaaatttaa gataataatg acagaagcat tgtctttata
     2641 tatttggggg tgcaacattt tgaatactga gaaattagaa acattgcttg gcttctataa
     2701 acaatataaa gcattatctg aatatattga taaaaaatat aagttgtcgc taaatgattt
     2761 agcagtctta gatttaacga tgaagtattg caaagatgaa aaagtactta tgcaatcatt
     2821 tttaaaaact gcaatggatg agctagattt aagtaggaca aaattattag tttctataag
     2881 aagactaatt gaaaaagaaa gacttag
//
LOCUS       DAPSKH010000119         2903 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPSKH010000119 DAPSKH010000000
VERSION     DAPSKH010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2903
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.123"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(211..2820)
                     /gene="adhE"
                     /locus_tag="RPH49_002627"
                     /gene_synonym="adhC"
     CDS             complement(211..2820)
                     /gene="adhE"
                     /locus_tag="RPH49_002627"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDY5125736.1"
                     /translation="MLTIPEKENRGSKEQEVAIMIDALADKGKKALEALSKKSQEEID
                     HIVHQMSLAAVDQHMVLAKLAHEETGRGIYEDKAIKNLYASEYIWNSIKDNKTVGIIG
                     EDKEKGLTYVAEPIGVICGVTPTTNPTSTTIFKAMIAIKTGNPIIFAFHPSAQESSKR
                     AAEVVLEAAMKAGAPKDIIQWIEVPSIEATKQLMNHKGIALVLATGGSGMVKSAYSTG
                     KPALGVGPGNVPSYIEKTAHIKRAVNDIIGSKTFDNGMICASEQVVVIDKEIYKDVTN
                     EFKAHQAYFVKKDELQRLENAIMNEQKTGIKPDIVGKSAVEIAELAGIPVPENTKLII
                     AEISGVGSDYPLSREKLSPVLALVKAQSTKQAFQICEDTLHFGGLGHTAVIHTEDETL
                     QKDFGLRMKACRVLVNTPSAVGGIGDMYNELIPSLTLGCGSYGRNSISHNVSATDLLN
                     IKTIAKRRNNTQIFKVPAQIYFEENAIMSLTAMDKIEKVMIVCDPGMVEFGYTKTVEN
                     VLRQRTEQPQIKIFSEVEPNPSTNTVYKGLEMMVDFQPDTIIALGGGSAMDAAKAMWM
                     FFEHPETSFFGAKQKFLDIGKRTYKIGMPENATFICIPTTSGTGSEVTPFAVITDSET
                     NVKYPLADFALTPDVAIIDPQFVMSVPKSVTADTGMDVLTHAMESYVSVMASDYTRGL
                     SLQAIKLTFEYLKSSVEKGDKVSREKMHNASTLAGMAFANAFLGIAHSIAHKIGGEYG
                     IPHGRANAILLPHIIRYNAKDPQKHALFPKYEFFRADTDYADIAKFLGLKGNTTEALV
                     ESLAKAVYELGQSVGIEMNLKSQGVSEEELNESIDRMAELAFEDQCTTANPKEALISE
                     IKDIIQTSYDYKQ"
BASE COUNT          819 a          564 c          464 g         1056 t
ORIGIN      
        1 cacgtagaga tgcatttttt gtaaaaagaa aaccatacgc atagcgtatg gttttctttt
       61 tacaaaaaaa tgattgtcta gtttgtatct ctctgaagat ttggcaataa ataaaagccg
      121 ataaccgtat aatgattatc gacttaaagt ttatgtggca ttttttactt ttgtaatttc
      181 aggtgagtta gatgattatt atcagataga ttattgctta taatcatatg atgtttgaat
      241 gatatctttg atttcactga ttagtgcttc tttaggatta gcagttgtac attgatcttc
      301 aaatgcgagc tctgccattc tatcaattga ctcatttaat tcttcttcag acacaccttg
      361 tgatttcaaa ttcatttcaa ttccgactga ttgacctaat tcgtagacag ctttagctaa
      421 tgattctacg agtgcttctg tcgtattacc ttttaatcct aagaatttgg caatatctgc
      481 ataatctgta tctgctctga agaactcata tttagggaat aatgcatgtt tttgtgggtc
      541 tttggcatta taacggataa tatgcggtag taatatcgca ttcgctctac catgcggaat
      601 accatattcg ccaccaattt tatgcgcaat tgagtgtgca atgcctaaga atgcatttgc
      661 aaatgccata ccagccaaag ttgatgcgtt atgcattttc tctcttgaaa ctttatcacc
      721 cttttcaaca gatgatttta aatattcgaa cgtcaattta atcgcttgta gactcaaacc
      781 tcttgtgtag tctgaagcca ttacagaaac atatgattcc attgcatgcg ttagtacatc
      841 cattcctgta tctgctgtaa cgctttttgg cacactcatc acaaattgag ggtcaataat
      901 tgcaacgtca ggtgttaaag caaaatcagc caacggatat tttacatttg tttcactatc
      961 tgtgataact gcaaatggtg ttacttctga acctgtacct gatgtcgtag ggatacaaat
     1021 gaacgtcgca ttttcaggca tgcctatttt ataagtacgt ttaccgatgt ctaggaactt
     1081 ttgtttagca ccgaagaatg atgtctcagg gtgttcaaag aacatccaca ttgcttttgc
     1141 agcatccatc gctgaaccac caccaagtgc aatgattgta tccggttgga aatcaaccat
     1201 catttccaga cctttatata ctgtattagt tgatgggttc ggttcgactt cgctaaatat
     1261 tttaatttga ggctgttccg ttctttgtct taatacattc tcaaccgttt ttgtataacc
     1321 gaattcgacc ataccagggt cacagacaat catcactttt tcaatcttgt ccattgctgt
     1381 taaactcatg attgcatttt cttcaaaata aatttgagca ggcaccttga aaatttgagt
     1441 attattacgt cgtttagcaa ttgttttaat gtttaataaa tctgtcgcac taacattatg
     1501 tgaaattgag tttctaccgt acgaaccaca acctaatgtt aaagacggaa tcaattcgtt
     1561 atacatatca ccaatacctc caaccgctga tggtgtattt acaagtacac gacaagcttt
     1621 cattcttagt ccaaaatctt tttgtaatgt ttcatcttct gtatggataa cggctgtgtg
     1681 tcctaatcca ccaaaatgta gtgtgtcttc acaaatttga aatgcttgtt ttgtagattg
     1741 ggcttttact aaggctaata ctggagataa tttttcacga gataacggat agtctgaacc
     1801 tacaccgcta atttcagcta tgataagttt tgtattttcg gggacaggta tacctgctaa
     1861 ttcagctatt tcaactgcag atttaccgac aatatcaggc ttaatacctg ttttttgttc
     1921 attcataatt gcattttcta agcgttgtaa ttcatctttt ttaacaaagt atgcttgatg
     1981 tgctttaaat tcattagtaa cgtctttata aatttcttta tcaataacta caacttgttc
     2041 agaagcacaa atcataccat tatcaaatgt ttttgaacca atgatatcat ttactgcacg
     2101 tttaatgtgt gctgtttttt caatgtaaga cggcacgtta cctggtccca cacctaatgc
     2161 cggtttgcca gttgaatatg cagacttaac catgcccgaa ccacctgttg ctagaactaa
     2221 tgcaatacct ttgtgattca ttaattgttt tgttgcttcg atagaaggca cttcaatcca
     2281 ttgaataata tctttaggtg cacctgcctt cattgccgct tctaatacaa cttctgctgc
     2341 acgcttcgac gattcttgcg cacttggatg gaatgcaaaa atgattggat ttcctgtctt
     2401 aattgcaatc atcgctttaa aaatagttgt cgacgtagga tttgttgttg gcgtaacacc
     2461 acaaataaca ccaattggtt ccgctacata cgttaatcct ttttctttat cttcaccaat
     2521 aatccctact gtcttattgt cttttattga attccatata tattcagaag cgtataaatt
     2581 tttaatcgct ttatcttcgt atatacctct tccagtttct tcatgtgcta attttgctag
     2641 caccatatgt tgatcaacag ctgctaagct catttgatga acaatatgat caatttcttc
     2701 ttgtgacttt ttagataatg cttctaatgc ttttttccct ttgtcagcta gagcatcaat
     2761 cataattgcc acttcttgtt ctttcgatcc acgattttct ttttcaggta tagttaacat
     2821 atacaaccac tcctttatac tttgtgaatt atttcacaaa cattatagta catgtctctc
     2881 aggatataaa gaaaattcta tac
//
LOCUS       DAPSKH010000120         2899 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPSKH010000120 DAPSKH010000000
VERSION     DAPSKH010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2899
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.124"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            99..470
                     /locus_tag="RPH49_002628"
     CDS             99..470
                     /locus_tag="RPH49_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDY5125737.1"
                     /translation="MLKKWLGMALITPILTFIIWVFNSHTIITYLNILFYVSLIIFIS
                     IFLILLVQEGIFDATSYGFRRLKYQMSSSKKKKSISDDPFFNPQEVKKEHYFVSTWII
                     PLLLINILYFIMTIVLSLILV"
     gene            complement(525..1769)
                     /gene="fabF"
                     /locus_tag="RPH49_002629"
     CDS             complement(525..1769)
                     /gene="fabF"
                     /locus_tag="RPH49_002629"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDY5125738.1"
                     /translation="MSQNKRVVITGMGALSPIGNDVKTTWENALKGVNGIDKITRIDT
                     EPYSVHLAGELKNFNIEDHIDKKEARRMDRFTQYAIVAAREAVKDAQLDINENTADRI
                     GVWIGSGIGGMETFEIAHKQLMDKGPRRVSPFFVPMLIPDMATGQVSIDLCAKGPNGA
                     TVTACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIET
                     ACRPFQEGRDGFVMGEGAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPE
                     GEGGSRAMQAAMDDAGIEPKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSS
                     TKSMTGHLLGATGGIEAIFSALSIKDSKVAPTIHAVTPDPECDLDIVPNEAQDLDITY
                     AMSNSLGFGGHNAVLVFKKFEA"
     gene            complement(1781..2722)
                     /locus_tag="RPH49_002630"
     CDS             complement(1781..2722)
                     /locus_tag="RPH49_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDY5125739.1"
                     /translation="MNVGIKGFGAYAPEKIIDNAYFEQFLDTSDEWISKMTGIKERHW
                     ADDDQDTSDLAYEASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGK
                     VASMDQLAACSGFMYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDRSTAVLFGDG
                     AGAVIIGEVSEGRGIISYEMGSDGTGGKHLYLDKDTGKLKMNGREVFKFAVRIMGDAS
                     TRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPL
                     SIDQELKNGKLKDDDTIVLVGFGGGLTWGAMTIKWGK"
BASE COUNT          880 a          579 c          431 g         1009 t
ORIGIN      
        1 gaatttcaat aaagctgaag aaattaaaaa atcattcctc aatgtctcat tttaatgtaa
       61 actatgcgta agagttttct ataagtggga gtgatcaaat gttgaaaaaa tggcttggaa
      121 tggcactaat aacgccaata ttaacgttta ttatatgggt ttttaatagc catactatca
      181 ttacatattt aaatatattg ttttatgttt cattaattat ttttattagc atatttttga
      241 ttttacttgt acaagaaggc atttttgatg cgacaagtta tggttttaga agattaaagt
      301 atcaaatgtc atcttcgaaa aagaagaagt ctatctctga tgatccattt ttcaacccac
      361 aagaggtaaa aaaagagcat tactttgttt ctacatggat aatcccctta ttattaataa
      421 atattctata ttttattatg acgattgtgc tgtcgctcat cttagtataa agaaacagaa
      481 aaaatcttca gtaactaaaa caacgttact gaagattttt ataattatgc ttcaaatttc
      541 ttgaatacta atactgcgtt atgtccaccg aatcctaagc tattactcat tgcataagta
      601 atatcaaggt cttgcgcttc atttggaaca atatccaaat cacattctgg gtctggtgtt
      661 accgcatgaa ttgtcggtgc gactttagag tctttaattg aaagcgctga gaagattgct
      721 tcaattccac ctgttgcacc aagtaagtga ccagtcattg attttgttga gctaactttt
      781 aagtgtttag ctgcttcacc aaatgtattt ttaatagctt taacttcatt taagtcacca
      841 acaggagtac ttgtaccatg ggcatttaag tattgtacat ctttaggttc aataccagca
      901 tcatccatag ctgcttgcat tgctctagaa ccgccttcac cttctggagc tggcgctgta
      961 atatgataag catcacctgt agtaccatag ccaactatct cagcataaat attggcacct
     1021 cgagcttgtg ctgattctaa agattcgatt actaaaatac cagcaccttc acccataaca
     1081 aaaccgtctc taccttcttg gaatggacga catgctgttt caatgtcatc atttgtagaa
     1141 agcgctcgac ttgcactgaa accagcaatt gccatatgag taattggtgc ttctgtacca
     1201 ccagtaatca ttgcatctgc atcaccgcgt tgcacaattt taaatgcttc tccgattgaa
     1261 tttgtacctg ttgcacatgc tgtaactgtt gcaccatttg gtccttttgc acataagtca
     1321 attgatactt gcccagttgc catatcagga attaacattg gtacgaaaaa tggactcaca
     1381 cgtcttgggc ctttatccat taattgttta tgtgcaattt caaatgtttc cataccaccg
     1441 ataccagaac caatccatac accgattcga tctgcagtat tttcattgat atctaattgc
     1501 gcatctttaa cagcctctct agctgctaca attgcatatt gagtaaatct atccatacga
     1561 cgcgcttctt ttttgtcgat atgatcttca atattaaagt ttttaagttc tcctgctaag
     1621 tgaacgctat aaggttcagt atcgatacgt gtaattttat cgataccatt tacgcctttt
     1681 agagcattct cccatgttgt tttgacatca ttaccgattg gagaaagggc tcccatacct
     1741 gtaataacta ctcttttatt ttgactcatt cgttatcctc ctattttccc cattttattg
     1801 tcattgcgcc ccaagttagg ccgccaccga atccgacaag aacaattgta tcatcatctt
     1861 tgagtttacc attttttaat tcttgatcga tacttaaagg tattgacgca gctgaagtat
     1921 ttccatattt atttacagaa acactcattt tgtcttttga aatacctaag cgttctctag
     1981 ctgattccat aattctaata ttagcttgat gaggaataaa taaatctata tcatctgatg
     2041 ttaaattcgc tttttcaact acacgtgttg atgcatcacc cataattcta acagcaaatt
     2101 taaatacttc tcgaccattc attttcagtt taccagtatc tttatctaaa tataaatgtt
     2161 taccaccagt gccatcagaa cccatttcat aacttataat acctctgcct tctgaaactt
     2221 caccgataat aaccgcacct gcaccatctc caaatagaac tgcagtagaa cggtcagtta
     2281 aatctgttat tttagataat ttatctgcac cgacaactaa aatattatga taatctccag
     2341 attgaacata ttgtttagct gtaatcattg aatacataaa tcctgaacat gctgcaagtt
     2401 gatccataga ggcaactttg cccgtcccta aacgttcttg caacatattt gcgacagttg
     2461 gaaatggcat atctccagtt gctgtggcaa caattatcat atctatatct tcgggctgaa
     2521 taccagcgtc agcgattgct tttacacttg cttcatatgc taaatctgaa gtatcttgat
     2581 cgtcatctgc ccaatgtctt tctttaattc cagtcatctt agaaatccat tcatcagatg
     2641 tatctaaaaa ttgctcaaaa taggcattgt caataatctt ttctggtgca tatgcaccaa
     2701 aacctttaat acccacgttc atagttgaac accttcttaa taaaattttt aataccaggt
     2761 attaatttaa catagattac tttttaaact caagtcagag gtaggaatat tgactagtta
     2821 ataaaatttt aatgctttat tatcgtcaaa ttccagtatg aaatttgttt taatgtgctt
     2881 aaattagaat agccattca
//
LOCUS       DAPSKH010000121         2649 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPSKH010000121 DAPSKH010000000
VERSION     DAPSKH010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2649)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2649)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2649
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.125"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..499)
                     /locus_tag="RPH49_002631"
     CDS             complement(<1..499)
                     /locus_tag="RPH49_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125740.1"
                     /translation="MSDRFIKFNDEQLDAKQVMMLQDLARLLLKNEQTQVKIQKFPYY
                     NPVQNVLITSWFWSHRPSHIEMAGLKTDVMLAAYGYHMMDVQIVNEVVQDKTFKHPKF
                     YQQLFKLLEDMRVLNSIKVERPSTAKLIDLRLDTRVSYTESQIKVYRTKTQYTDLLFL
                     YLEHAF"
     gene            complement(513..1304)
                     /locus_tag="RPH49_002632"
     CDS             complement(513..1304)
                     /locus_tag="RPH49_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDY5125741.1"
                     /translation="MALKHYKNSDSTVFNDAKALFDLNKNILLKGPTGSGKTKLAETL
                     SEVVDTPMHQVNCSVDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYID
                     EINMAKPETLPVLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLPMNEAL
                     KNRFVVIHVDYIDGDILKNVIKEQSLLQDDKQIEQIIKFNEDLRTMSKQGQISEEAAS
                     IRALLDLCDLITVMPVERAIKRTIIDKLEDEREQQAIYNAVELNF"
     gene            complement(1485..1688)
                     /locus_tag="RPH49_002633"
     CDS             complement(1485..1688)
                     /locus_tag="RPH49_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499941.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125742.1"
                     /translation="MLHETWKERTPIKKVEVINTDAKKFTVSDMLTVGKQYDVINETE
                     EYYQIIDNSGLVGGYYKTYFKEV"
     gene            complement(1717..2526)
                     /locus_tag="RPH49_002634"
     CDS             complement(1717..2526)
                     /locus_tag="RPH49_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDY5125743.1"
                     /translation="MCGLRSITLGTTNIEQTKHFMVDILGLNYEELLENSIRFGDADI
                     SPGTRLQFIQVPSEQLEESHFVGIGLRTPTDSGLEEYAEILSNKDIPFTTVKELNGNK
                     YFSLEDNNGHIFSIYSNENNYGVGLGMPSFESAVNPLHQVQGLGPVILKVNHVDITGQ
                     ILTNIFGLEVFAEYQPFDNADYHVQVFKVGTGGLGGEIHLMPVETEMTMPEYGAVDQV
                     EFETKDADFFNQAKSRLDEVEIPYQTLEQDDIESIRITENSGLSFIFTLQK"
BASE COUNT          818 a          473 c          361 g          997 t
ORIGIN      
        1 aaaatgcatg ttctaaatac aaaaataata aatctgtata ttgtgtttta gtacgataca
       61 ctttaatttg agattccgta tatgataccc gtgtatctaa gcgaagatca attaatttag
      121 cagtacttgg gcgctcaact ttaatagaat ttaatacacg catatcttct aacaatttaa
      181 aaagttgttg ataaaattta gggtgtttaa aagttttatc ttgtactact tcatttacaa
      241 tttgtacatc catcatatga taaccgtaag cagctaacat aacatctgtt tttaaaccag
      301 ccatttcgat atggcttggt cgatgtgacc aaaaccaact cgtaatcaaa acattttgaa
      361 caggattata gtaagggaat ttttggattt taacttgtgt ttgttcattt tttaataaga
      421 gtcgagctaa gtcttgcaac atcattactt gctttgcatc taactgttcg tcgttaaatt
      481 ttatgaaacg atcactcatg ttttatccct ctttaaaagt ttagttctac agcattatat
      541 attgcttgtt gttcacgttc atcttccaat ttatcaatta ttgtacgttt aattgcacgt
      601 tcaactggca ttacagtgat taaatcacac aagtctaata atgcacggat actagcggct
      661 tcttcagaaa tttgtccctg cttagacata gtacgtaaat cttcgttaaa cttaataatt
      721 tgttcgattt gtttatcatc ttgtaataaa ctttgctctt taatcacatt ttttaaaatg
      781 tccccatcaa tatagtcaac gtgaataaca acaaagcgat tttttagtgc ttcattcatt
      841 ggcaatgtac caacataacc ttcatttatc gctgctataa cgttaaatcc tggtacagct
      901 ttgattactt caccagtgta tggattcgta atttgacgac gataatctaa gaccccattt
      961 aatacaggca atgtttcagg tttagccata tttatttcat caatatataa aatatgcccc
     1021 tctttcatag ctttaataac tggaccatct acaaagacaa tttcttgttg tccttccgca
     1081 tttgttttaa ttgttttaaa gcctaataag ctttctgtat ctaaatcaac agaacagttg
     1141 acttgatgca tgggtgtatc aacaacttca cttaatgttt ctgccaactt cgttttccct
     1201 gaacccgttg gacctttaag taaaatattt ttatttaaat caaataatgc cttcgcatca
     1261 ttgaaaactg ttgaatctga attcttataa tgttttagtg ccattttaaa acgttctcct
     1321 ttaaataaat taaaaaacta agacatggaa taagttctcc aaatgcctta gtttactatt
     1381 ctattctgat ataaaacgca atgcttagta tgcgaattgt ttatatttta ccaaatttac
     1441 taattgaaaa tctcatatta ggcttcattt caataattat gcgtttaaac ttctttgaaa
     1501 tatgttttat agtaaccgcc aactaatcca gaattatcta ttatttgata atattcttca
     1561 gtttcgttga taacatcata ttgtttgcca accgttaaca tgtcagaaac tgtaaatttc
     1621 tttgcatctg tattaatgac ttctactttc ttgattggtg tacgttcttt ccaagtttca
     1681 tgtaacataa attttgtcct cactatcgta aaaaaattat ttttgtaaag tgaatataaa
     1741 cgataatcca ctgttttcag taattctaat tgattcaata tcatcttgct caagcgtttg
     1801 atatggtatt tccacttcat ctaagcgcga tttcgcttga ttaaagaaat ctgcatcttt
     1861 cgtttcaaac tcaacttgat cgactgcgcc atattccggc attgtcattt cggtttctac
     1921 aggcattaaa tgtatttcgc cacctagacc acccgttcca actttgaata cttggacatg
     1981 atagtcagca ttgtcgaagg gttggtattc tgcaaatact tcaagtccga atatatttgt
     2041 taaaatttga cctgtaatat ctacatgatt cactttaaga atcactggtc ctaaaccttg
     2101 cacttgatgt aacggattga ccgcactctc aaaagaaggc atacctaaac caacgccata
     2161 attattctcg tttgaatata ttgagaaaat atgaccattg ttatcttcta gactgaaata
     2221 tttattgcca tttaattctt taactgttgt aaatggaata tccttattcg ataatatttc
     2281 cgcatactcc tctaaacctg agtcagttgg tgtacgtaat ccaataccca caaagtgaga
     2341 ttcttctaat tgctcacttg gaacttgtat aaattgaagt cttgttcctg ggcttatatc
     2401 tgcatcgccg aaacgaattg agttttcaag aagttcttca taatttaatc ctaatatgtc
     2461 aaccatgaaa tgttttgtct gttctatatt tgttgtacct aatgttatac ttctaagtcc
     2521 acacattata gccacctcta tctttatctt tactattata ttataactta ttttaatcat
     2581 aaattataga atatcggtca gttgattttg attatagatt aatatgtgaa aaatgtattt
     2641 ctttaaaag
//
LOCUS       DAPSKH010000122         2571 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPSKH010000122 DAPSKH010000000
VERSION     DAPSKH010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2571
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.126"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            92..601
                     /locus_tag="RPH49_002635"
     CDS             92..601
                     /locus_tag="RPH49_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125744.1"
                     /translation="MIRLGKMSDLDQILNLVEEAKELMKEHDNEQWDDQYPLLEHFEE
                     DIAKDYLYVLEENNKIYGFIVVDQDQAEWYDDIDWPVNREGAFVIHRLTGSKEYKGAA
                     TELFNYVIDVVKARGAEVILTDTFALNKPAQGLFAKFGFHKVGEQLMEYPPYDKGEPF
                     YAYYKNLKE"
     gene            613..1683
                     /locus_tag="RPH49_002636"
     CDS             613..1683
                     /locus_tag="RPH49_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDY5125745.1"
                     /translation="MKKIAFTGGGTVGHVSVNLSLIPTALSHGYEALYIGSKNGIERE
                     MIESQLPEIKYYPISSGKLRRYISLENAKDVFKVLKGILDARKVLKKEKPDLLFSKGG
                     FVSVPVVIAAKSLNIPTIIHESDLTPGLANKIALKFAKKIYTTFEETLNYLPKEKADF
                     IGATIREDLKNGNAHNGYQLTGFNENKKVLLVMGGSLGSKKLNSIIRENLDALLQQYQ
                     VIHLTGKGLKDAQVKKSGYIQYEFVKEELTDLLAITDTVISRAGSNAIYEFLTLRIPM
                     LLVPLGLDQSRGDQIDNANHFADKGYAKAIDEEQLTAQILLQELNEMEQERTRIINNM
                     KSYEQSYTKEALFDKMIKDALN"
     gene            1700..2314
                     /locus_tag="RPH49_002637"
     CDS             1700..2314
                     /locus_tag="RPH49_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDY5125746.1"
                     /translation="MSQWKRISLLIVFTLVFGIIAFFHESRLGKWIDNEVYEFIYSSE
                     SFITTSIMLGATKVGEVWAMLCISLLLVAYLMLKRHKIEALFFALTMALSGILNPVLK
                     NIFDRERPTLLRLIDITGFSFPSGHAMGSTAYFGSGIYLLKRLNQGNSKGILIGLCAA
                     MILLISISRVYLGVHYPTDIIAGIIGGVFCIILSTLLLRNKLIN"
     gene            2431..>2571
                     /locus_tag="RPH49_002638"
     CDS             2431..>2571
                     /locus_tag="RPH49_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125747.1"
                     /translation="MTNPTRTKRCGGDVLCGIDNHFQLLLYISENHCQLETKTFFEYF
                     LRI"
BASE COUNT          952 a          330 c          472 g          817 t
ORIGIN      
        1 tcataataaa ggtttaaagc atgttaatag tgtgtaagat taacatgtac tgaaaaacat
       61 gtttaacata acgatataag gagtgacgta catgatccgt ctaggtaaaa tgtcagattt
      121 agatcaaatc ttaaatctag tagaagaagc aaaagaatta atgaaagaac acgacaacga
      181 gcaatgggac gatcagtacc cacttttaga acattttgaa gaagatattg ctaaagatta
      241 tttgtacgta ttagaggaaa ataacaaaat atatggtttt attgttgtcg accaagacca
      301 agcagaatgg tatgatgaca ttgactggcc agtaaataga gaaggcgcct ttgttattca
      361 tcgattaact ggttcgaaag aatataaagg agctgctaca gaattattca attatgttat
      421 tgatgtagtt aaagcacgtg gtgcagaagt tattttaacg gacacctttg cgttaaacaa
      481 acctgcacaa ggtttatttg ccaaatttgg atttcataag gtcggtgaac aattaatgga
      541 atatccgcca tatgataaag gtgaaccatt ttatgcatat tataaaaatt taaaagaata
      601 gaggtaatat taatgaagaa aatcgcattt accggagggg gaacagttgg acacgtatca
      661 gtaaatttaa gtttaattcc aactgcatta tcacatggtt atgaagcgct ttatattggt
      721 tctaaaaatg gtattgaaag agaaatgatt gaatcacaac taccagaaat taagtattat
      781 cctatttcaa gtggtaaatt aagaagatat atttctttag aaaatgccaa agacgtattt
      841 aaagtattga aaggtattct tgatgctcgt aaagttttga aaaaagaaaa acctgatcta
      901 ttattttcaa aaggtggatt tgtatctgtg ccagttgtta ttgcagccaa atcattaaat
      961 ataccaacta ttattcatga atctgactta acaccaggat tagcgaataa gatagcactt
     1021 aaatttgcca agaaaatata tacaacattt gaagaaacgc taaactacct acctaaagag
     1081 aaagctgatt ttattggagc aacaattcga gaagatttaa aaaatggtaa tgcacataat
     1141 ggttatcaat taacaggctt taatgaaaat aaaaaagtgt tactcgttat gggtggaagc
     1201 ttaggaagta aaaaattaaa tagcattatt cgcgaaaact tagatgcatt attacaacaa
     1261 tatcaagtga tacatttaac tggtaaagga ttaaaagatg ctcaagttaa aaaatcagga
     1321 tatatacaat atgaatttgt taaagaggaa ttaacagatt tattagcaat tacggacaca
     1381 gtaataagta gagctggatc aaatgcgatt tatgagttct taacattacg tataccaatg
     1441 ttattagtac cattaggttt agatcaatcc cgaggcgacc aaattgacaa tgcaaatcat
     1501 tttgctgata aaggttatgc taaagcgatt gatgaagaac aattaacagc acaaatttta
     1561 ttacaagaac taaatgaaat ggaacaggaa agaactcgaa ttatcaataa tatgaaatcg
     1621 tatgaacaaa gttatacgaa agaagcttta tttgataaga tgattaaaga cgcattgaat
     1681 taatgggggg taatgcttta tgagtcaatg gaaacgtatc tctttgctca tcgtttttac
     1741 attggttttt ggaattatcg cgtttttcca cgaatcaaga cttgggaaat ggattgataa
     1801 tgaagtttat gagtttatat attcatcaga gagctttatt acgacatcta tcatgcttgg
     1861 agctactaaa gtaggtgaag tctgggcaat gttatgtatt tcattacttc ttgtggcata
     1921 tctcatgtta aagcgccaca aaattgaagc attatttttt gcattaacaa tggcactatc
     1981 tggaattttg aatccagtac taaaaaatat attcgataga gaaagaccta cattgctgcg
     2041 tttaattgat ataacaggat ttagttttcc tagcggtcat gctatgggat caactgcata
     2101 ttttggaagt ggtatctatc tattaaaacg attaaatcaa ggtaattcaa aaggtattct
     2161 tatagggtta tgtgcagcta tgattttatt gatttccata tcacgtgtat atctaggtgt
     2221 gcattatcca acagatatta ttgccggtat tattggtggc gtattttgca ttattttatc
     2281 aacgttatta cttagaaata aattaatcaa ttaaatagta aaaaaacaaa agcagtaaac
     2341 ctaaagtgtc gtaagggttt actgctttta taaaacgttg ttataacgta tattgtcttt
     2401 tacgggcata taaaagggga atatttgaaa atgaccaatc caacaagaac gaaacgttgt
     2461 gggggggatg ttctatgtgg tattgataat cattttcaac tactattata cattagtgag
     2521 aatcattgtc aattagaaac taaaactttt tttgaatatt ttttaagaat a
//
LOCUS       DAPSKH010000123         2348 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPSKH010000123 DAPSKH010000000
VERSION     DAPSKH010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2348
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.127"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..74
                     /locus_tag="RPH49_002639"
     CDS             <1..74
                     /locus_tag="RPH49_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDY5125748.1"
                     /translation="QISMEEYLDPFTGEKNKKRKKKE"
     gene            680..1741
                     /locus_tag="RPH49_002640"
     CDS             680..1741
                     /locus_tag="RPH49_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit IIC"
                     /protein_id="HDY5125749.1"
                     /translation="MSNAKNADNKQFFSKILNSIGAGVVIALVPNALLGEVLKIFKSG
                     NEILELTYQLVILIQSFMAFIIGVLAAHQFKFNGAGAAIVGTSAMIGSGAVVYSNNSF
                     MLKGIGDIINTSLVVIIACLIYMVLQNKLGSFELIILPVLVPIVSGGIGLITLPYIRK
                     ITQAIGNVIHSFTDLNPLLMSILISVAFSLLMVTPISLVAIATAISLNGLGSGAANLG
                     IVAACVTFLFGSLRVNSIGVNAVLLIGAAKMMIPVYLKNLIISIPLTINGIITGIIAY
                     VLQVKGTPLSAGFGYTGLVGPINAFNRMSGDPTMNIILLALGYFVIPFVSAYIVHELC
                     KKFIPIYSNDIYKFEVPKQ"
     gene            2000..>2348
                     /locus_tag="RPH49_002641"
     CDS             2000..>2348
                     /locus_tag="RPH49_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDY5125750.1"
                     /translation="MKCLIRFILVLGLLISSAMVYINPTAHAEQDQTWEKIKERGELR
                     VGLSADYAPMEFEHTVNGKTEYAGVDIDLAKKIAKDNNLKLKIVNMSFDSLLGALKTG
                     KIDIIISGMTSTPE"
BASE COUNT          775 a          286 c          424 g          863 t
ORIGIN      
        1 accaaatctc aatggaagaa tatttagatc ctttcactgg agagaaaaat aaaaaaagaa
       61 agaaaaaaga gtaacccttt agggttgctg gaatagtagt gcagttggct gacttgtcag
      121 tgccctttta gggctggcca gtaaggaagg cttatagccg cagaacaaac cacccgttca
      181 cacgggtggt tttgatttct ctttatacaa tacaaataaa agtggctctc aaatggcaca
      241 ggctttaata ggatctatgt caaattgtac tgatgagttc aatataggaa gttaagcaac
      301 tatagattgt ttaacttctt tttttggtat tacattaatg ataatgacta tattatctgg
      361 ggttatgtat ttgtttaaac ttttctaata aaatatttgt aaaagttcta ttttattgtg
      421 ctttatagca agtcgattca atttatctat cttaatgcca atatggatat tttaatattt
      481 acaatttatt acattattag tcacaggatg taattagtaa tattttaaaa ttaacatgac
      541 attgattagt gagtagattt tcaaatttac tttattcctt ttgtggtttg ttatatttag
      601 attaaattag tcaactaatc attgttaaag ttaattttct ataatatgat gagtttaatg
      661 ttcaaattgg aggtcgttta tgagtaacgc aaagaatgct gataataagc agtttttcag
      721 taagatttta aattctattg gtgctggtgt tgttattgca cttgttccga atgctttatt
      781 aggtgaagta ttaaaaatat ttaaaagtgg taatgaaatt ttagaattaa cgtatcagtt
      841 agtgatacta attcaatcat ttatggcatt tattattggg gttttagctg ctcatcaatt
      901 taaatttaat ggcgcaggtg ctgctatagt aggtacatca gctatgattg gttcaggtgc
      961 tgttgtatat agcaataata gttttatgtt aaaaggtata ggtgacatta taaatacgag
     1021 tttggttgtt attattgcat gtcttatata tatggtatta caaaacaaac ttggatcttt
     1081 tgaattaatt atattaccag ttttagtacc tatcgttagt gggggtatcg gtctaatcac
     1141 attaccttac attcgaaaaa ttactcaagc aattggaaat gtaattcatt cttttacaga
     1201 cttaaatccg ttgttaatgt ctatacttat tagtgtggca ttttcattat taatggtaac
     1261 accaatatcg ttagtagcga ttgcaactgc gattagttta aacggactag gaagtggagc
     1321 agcaaaccta ggtatagtgg ctgcctgtgt tactttctta tttggctcat tgcgtgtcaa
     1381 ttctattggt gtaaatgcag ttttactcat aggagctgca aaaatgatga tcccagttta
     1441 cttgaaaaat ttaattattt cgataccatt gactataaat ggaataatta ctggaatcat
     1501 tgcttacgtt cttcaggtta aaggaacacc attgtctgct ggatttggat acacaggatt
     1561 agttggccca ataaatgcat ttaaccgaat gtcaggtgat ccaacaatga atattatttt
     1621 attagcactt ggttattttg tcataccatt tgtatcggca tatattgttc atgaattgtg
     1681 taaaaaattc attcctatat attctaatga tatttataaa tttgaagttc caaaacaata
     1741 atttatagct tgatgacaag aataagtttt aatatatgat aaatataggc gttactgtca
     1801 ataagatatt gatagtagcg ctttttttga ttgattttat aatgaaagaa ttgttcgcgt
     1861 ataatagacg attttttaag tacagtcttt taaaaagaag cttttcttta tattgataaa
     1921 aatacattta taaaacacta ttgcatcaaa atgtattaat atgtataatt atgaatatta
     1981 attagggagg gctgtataaa tgaagtgttt aattaggttt atattagtat tagggttgtt
     2041 aattagcagt gctatggtgt atatcaatcc cacagcacat gctgaacaag atcaaacatg
     2101 ggagaagatt aaagaacgcg gtgaacttag agtgggtctt tctgcagatt atgcaccaat
     2161 ggaatttgag catacagtta atggtaagac tgagtatgca ggtgtagata ttgatttagc
     2221 taaaaaaatt gcgaaagata ataatttaaa attaaaaatc gtcaatatgt catttgatag
     2281 tttgttagga gctcttaaaa ctggaaaaat tgatattatt atttccggaa tgacttcaac
     2341 gcctgaac
//
LOCUS       DAPSKH010000124         2338 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPSKH010000124 DAPSKH010000000
VERSION     DAPSKH010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2338
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.128"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(334..1341)
                     /locus_tag="RPH49_002642"
     CDS             complement(334..1341)
                     /locus_tag="RPH49_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter"
                     /protein_id="HDY5125751.1"
                     /translation="MSYIIIVTIAVVIFSLIFDFINGFHDTANAVATAVSTRALTPKT
                     AILMAAVMNFIGALTFTGVAGTITKDIVDPFKLENGLVVVLAAILAAIVWNLATWFYG
                     IPSSSSHALIGSIAGAAIASEGSFGVLHYQGFTKIIIVLIVSPIIAFCVGFLMYSIFK
                     VIFKNANLTRANRNFRFFQIFTAALQSFSHGTNDAQKSMGIITLALIVANVQNDGSVE
                     PQLWVKFACATAMGLGTAIGGWKIIKTVGGNIMKIRPANGAAADLSSALTIFVASSLH
                     FPLSTTHVVSSSILGVGASNRAKGVKWSTAQRMIITWVITLPISALLAGLLFYILNLF
                     F"
     gene            complement(1357..1974)
                     /locus_tag="RPH49_002643"
     CDS             complement(1357..1974)
                     /locus_tag="RPH49_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF47 domain-containing protein"
                     /protein_id="HDY5125752.1"
                     /translation="MFSKKKDKFMVQLEEMVFNLDRAAIEFGKMDFNTHLDLKAYSDN
                     IKTYESHGDELVHQVITDLNQTFITPIEREDILSLCDAIDDVLDAIEETAAMFEMYSI
                     EYTDEYMAEFVDNIQKAVAEMKLAVGLLVDKKLSHMRIHSINIKEFETNCDGILRQSI
                     KHIFNSETDPITLIKIKDIYESMEEIADKCQIVANNFETIIMKNS"
BASE COUNT          811 a          407 c          320 g          800 t
ORIGIN      
        1 cagtatttta cgctttttcg tctacatata caaatttata ttaaataaag tccaatacaa
       61 tttaggttaa tcaaacaagt tgatagctat ttaattattc attcattgca gaatataaac
      121 tattaaatca ttattttacg cttacttata ttttaatgac ctaactgttt atgttccatg
      181 gaatacattt ataacttagc ccctaattaa aatgctttgt cttggtcatt ctatgtaaat
      241 tctataaaat atgttatcta tttacataaa aaactgaact tcaataccac cacatttttg
      301 tgatactgaa gttcagttta gttttatttt caattagaaa aataagttaa gtatatagaa
      361 tagtaaacct gctaacaatg ctgaaatagg taatgtaatc acccatgtaa tgatcattcg
      421 ttgcgcagta ctccatttta cacctttagc tcggttagaa gcaccaacac ctaagattga
      481 tgatgacaca acgtgagttg ttgataatgg gaaatgtagc gatgatgcaa caaaaattgt
      541 taatgcagat gataaatcgg ccgcagcacc atttgctgga cgtattttca taatattacc
      601 acctacagtt ttgataattt tccagccacc aattgcagta ccaagcccca ttgctgtcgc
      661 acaggcaaat tttacccata actgtggttc aacgctgcca tcattctgta cattagcaac
      721 aatcaatgcc aacgtaataa tacccattga tttttgcgca tcattcgtac cgtgagagaa
      781 tgattgtaac gctgctgtga aaatttggaa aaatctaaag ttacgattcg ctcttgttaa
      841 atttgcattt ttaaagataa ctttaaaaat tgaatacatc aagaaaccaa cacaaaatgc
      901 gataatcggt gaaacgatta atacaataat aatttttgtg aaaccttggt aatgtaacac
      961 tccaaatgag ccttcagatg cgattgctgc tcccgcaatt gaacctataa gtgcatgtga
     1021 agacgaactt ggaattccgt aaaaccaagt agctaaattc caaacaatag ccgcaagtat
     1081 tgcagctaac acaacaacta agccattttc caatttaaat ggatcgacaa tgtctttagt
     1141 aatggtgcct gcaacgcccg taaatgttaa agcacctata aagttcatca ctgctgccat
     1201 taaaattgcc gttttaggcg ttaacgctct agtagataca gcagtagcta ctgcattggc
     1261 tgtatcatgg aatccattga taaagtcaaa tatcagcgag aaaataacta cagctatagt
     1321 gacgatgatt atatatgaca taaatataaa ctccccttag ctatttttca taataatagt
     1381 ttcaaaatta tttgctacga tttgacattt atcagcgatt tcttccatgc tttcataaat
     1441 atcttttatt ttaattaaag tgattggatc tgtttcgcta ttgaaaatat gtttaattga
     1501 ctgtcttaaa ataccatcac agtttgtttc aaattcttta atattaattg aatgaatacg
     1561 catatgtgat aattttttat cgactaataa gccgacagca agtttcattt ctgcaactgc
     1621 tttttgaatg ttatcaacaa actcagccat atattcatct gtgtattcga ttgaatacat
     1681 ttcaaacata gctgccgttt cttcaattgc atctaaaaca tcatcaattg catcacataa
     1741 tgataaaata tcttcacgtt caattggtgt gataaatgtt tgatttaaat cagtaattac
     1801 ttgatgtact aattcgtcac catgtgactc ataagtttta atgttgtctg agtatgcttt
     1861 taaatctaaa tgagtattga aatccatttt accgaattca atagcagcac gatccagatt
     1921 gaaaaccatc tcttctaatt gaaccataaa cttatctttt ttcttactaa acatttaaaa
     1981 tcctccattt aagcgattgt caccaatcac attcagttat aatttgtttc aaattaagac
     2041 aagtgaattt acaaactaat gatacaaatt tgttattatc aatcgtcagt ataatttaag
     2101 tgtactgata ttaatttcaa aaatgcctca cagtaaacaa tttactgtat ttgcccttat
     2161 atgaaaatag cacaaaattt acaatcccac aattcaattt acaaattttt aacaattccg
     2221 aaacttaact tttacataaa atttaaatag tggtaggcat ttgttttgaa aaacttgata
     2281 tataggcaat ttgttatcta caaaactcta ataattgtaa atggacatag ttggaaat
//
LOCUS       DAPSKH010000125         2332 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPSKH010000125 DAPSKH010000000
VERSION     DAPSKH010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2332
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.129"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            3..392
                     /locus_tag="RPH49_002644"
     CDS             3..392
                     /locus_tag="RPH49_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5125753.1"
                     /translation="MVGYLLHKSKKEHYIETQEKRIDLYFKYNLNNYHSMKVTSFKKN
                     PMGGYFIKGFVNNKKNYKFDAVIFSDTNKQFKGDLGYKEDEIGELFREKNANDRLTVD
                     EIIEKEHLDKSEYEAEPPLFFFSGPLE"
     gene            598..975
                     /locus_tag="RPH49_002645"
     CDS             598..975
                     /locus_tag="RPH49_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1433 domain-containing protein"
                     /protein_id="HDY5125754.1"
                     /translation="MNKKPLVIVFIIIILILGGIFLKMKYDEMKYYDEQKERIILFMK
                     YNVKGFKEIQFEEQKENPMDGYSISGYINNDKKLSFTAGIRSVDDFQFDTDISYTDEL
                     GRKFNKNPKSVSEIKKEQNTSNK"
     gene            1169..1341
                     /locus_tag="RPH49_002646"
                     /pseudo
     CDS             1169..1341
                     /locus_tag="RPH49_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066885.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1319..1420)
                     /locus_tag="RPH49_002647"
     CDS             complement(1319..1420)
                     /locus_tag="RPH49_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125755.1"
                     /translation="MQGFKEKHQELKSALCQIGLMRSISEVRQLNIA"
     gene            complement(1543..1638)
                     /gene="pepA1"
                     /locus_tag="RPH49_002648"
     CDS             complement(1543..1638)
                     /gene="pepA1"
                     /locus_tag="RPH49_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin
                     PepA1"
                     /protein_id="HDY5125756.1"
                     /translation="MMLIFVHIIAPVISGCAIAFFSYWLSRRNTK"
     gene            1783..1887
                     /locus_tag="RPH49_002649"
     CDS             1783..1887
                     /locus_tag="RPH49_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001807442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125757.1"
                     /translation="MVRLYENGKPRNEIIREYDLTPLTLGKWIKQHQK"
     gene            2061..2285
                     /locus_tag="RPH49_002650"
     CDS             2061..2285
                     /locus_tag="RPH49_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDY5125758.1"
                     /translation="MGKVLKILRSTYYDSIKRKDNKITKDDSNVERAVINIFNSNRKV
                     FGTGRIKNNLNDKGLSVSRRKIGRIMKNII"
BASE COUNT          936 a          278 c          374 g          744 t
ORIGIN      
        1 ttatagtagg gtatttgtta cacaaaagta aaaaagaaca ttatattgag acacaagaaa
       61 agcgaataga tttgtatttt aaatataatc ttaacaatta tcattcaatg aaagttacaa
      121 gttttaaaaa gaatccaatg gggggttatt ttataaaagg ctttgtcaat aataaaaaaa
      181 attataaatt tgatgctgtg atattttctg atactaataa acaatttaaa ggagatttag
      241 gttataaaga ggatgaaata ggtgaattat ttagagaaaa aaatgctaat gaccgattaa
      301 ctgtcgatga aataattgaa aaagaacact tggacaaaag tgaatatgaa gccgagccac
      361 cgttattttt cttttcaggt ccacttgaat aaataatatg aatagattag ataatttaat
      421 gatttatatt ttaaaggaaa ctaaatctat attaaagaat atgtaaaact aaaatttact
      481 aatgttaaaa ccattagtca tatgggttgc aacgttttta cattcatcgt aatactctgt
      541 atgcttcatt aatttaaaat gttcgtcaat aaatccaatg aaaaggagat gggttttttg
      601 aataaaaaac ctcttgtgat tgtatttata attataatat tgattctagg cggaatcttt
      661 ttgaagatga aatatgatga aatgaaatat tatgatgagc aaaaagaaag aatcatatta
      721 tttatgaaat ataatgttaa agggtttaaa gaaatacaat tcgaggaaca aaaagaaaac
      781 ccaatggatg gttattctat tagtggttat ataaataatg ataaaaagtt atcatttaca
      841 gctggtataa gatctgttga tgattttcaa tttgataccg atatttctta tacagatgaa
      901 ttgggtagaa aatttaataa aaatcctaag tcagtttctg aaataaagaa agagcaaaat
      961 acgtccaata aataattgtt catattgtga tgaaacaaaa atataagtca ttagatgaat
     1021 ttaactatgt tataaatatt tgtagtatct ataaaaatct cgacactatt aaaatgatat
     1081 agtgccgagg ttttcttact tatttagtta attcaaagtt tatgccagat tcataagaat
     1141 ttgtgacact tttaatagtg taaccattga ttattacaat ttatcaaatg gtcctttaga
     1201 agggataaac aacaaaattt aattaaacgt acatcttttg gttaaggaag ttataatcat
     1261 ttgcgaaatc gaatattatt atgtttaaaa ctttacgctc caaaaagtaa aaaggaagct
     1321 aagcaatgtt tagttgccta acttcggata ttgaacgcat cagtccaatt tggcatagag
     1381 cactctttag ttcttgatgt ttctctttaa aaccttgcat attttacaaa aagaaaaatt
     1441 agcagtataa ttgagataac gaaaataagt atttacttat acaccaatcc cctcactatt
     1501 tgcggtagtg aggggatttt tattggtgcg gctatatgtc acctattttg tattgcgtct
     1561 acttagccaa taagaaaaaa acgcaatggc acagccactg atgactggtg ctatgatgtg
     1621 aacgaaaata agcatcacct tatacacctc ctctctgcgt ctaaattgac gcctgagaga
     1681 taggcgactc tactattata tcatctaatt ggacaaattc tatgagagta gattttgtta
     1741 atttaagaaa gaagaacatt tagttcagag tttaagttat aaatggttag attatatgaa
     1801 aatggtaagc caagaaatga aattatacgc gagtatgatt taacaccttt gacgttagga
     1861 aaatggataa agcaacatca aaaataaggt tcattcaatc atcaagataa cttaacagat
     1921 gaagaaaaag agctgattaa attacacaaa gaagttcaac atttaaaaat ggagaacgat
     1981 attttaaagc aagcagcgct gattatggga cgaaaataga agtcattcaa aagaatgcac
     2041 atcaatattc agtatcagca atgggtaaag tcttaaaaat actaagaagt acctattatg
     2101 attctataaa aagaaaagat aataaaatca ctaaagatga ttcaaacgta gaacgtgccg
     2161 tcataaatat ttttaattct aatagaaaag tctttggtac aggacgaatt aaaaataatt
     2221 taaatgataa gggtctctct gtatcaagac gaaagatagg tcgtatcatg aaaaacataa
     2281 tctagtttct gtttatacga aagctaaata caaaaatcat ctaaaagaaa ct
//
LOCUS       DAPSKH010000126         2239 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPSKH010000126 DAPSKH010000000
VERSION     DAPSKH010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2239)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2239)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2239
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.130"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..199
                     /locus_tag="RPH49_002651"
     CDS             <1..199
                     /locus_tag="RPH49_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125759.1"
                     /translation="KMTKKEFIDIPVLFDDEGNFRIKQVIDYKKIIGKSYVNGKYIET
                     KLGKVHYSKTGFHVVPYIKKE"
     gene            206..397
                     /locus_tag="RPH49_002652"
     CDS             206..397
                     /locus_tag="RPH49_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LSM domain protein"
                     /protein_id="HDY5125760.1"
                     /translation="MNLQSYIGKLVKLTLTNNKILIGKVIDFDDKVDNFDGYNSIEID
                     TGRITYDISENKIKTIVLQ"
     gene            complement(946..1971)
                     /locus_tag="RPH49_002653"
     CDS             complement(946..1971)
                     /locus_tag="RPH49_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low specificity L-threonine aldolase"
                     /protein_id="HDY5125761.1"
                     /translation="MISFENDYLEGAHEKVLKRLVDTNLVQASGYGFDQFTNQAIEKI
                     KDTIDCPNATIRFLVGGTQTNQVVINSMLESYEGVISADTGHVAVHEGGAIEYSGHKV
                     ITIPSKEGKVSASDVETYMETFKSDFKKDHMVFPGMVYISHPTEYGTLYSKSELEELC
                     KVCKQYQLPLFMDGARLGYGLMSDQSDMTIKDIAKYCDVFYIGGTKIGALCGEAIVFT
                     KNNEPKQFTTRIKHHGALLAKGRLTGIQFLELFTDNLYFNISRHAIEMANKMKDGFKN
                     KGYRLYFDSPTNQQFFILSNEKIAELEQKVKFAVWEKYDDQHRVVRFATSWATTEENL
                     NKLLELI"
BASE COUNT          812 a          358 c          290 g          779 t
ORIGIN      
        1 aaagatgact aaaaaagaat ttattgatat tccagttttg tttgatgatg aagggaattt
       61 tagaataaaa caagttatag attataaaaa gataataggt aaatcttatg tgaatggtaa
      121 atatattgaa acgaaattag gtaaggttca ttattctaaa actggttttc atgtagttcc
      181 gtatattaaa aaggagtgat taaatatgaa tttacagtca tacataggca aattagtcaa
      241 attaacgctt actaataata aaatattaat tggaaaagtg atagactttg atgataaagt
      301 tgataatttt gatggttata attcgataga aattgataca ggtagaatta catatgatat
      361 atcagaaaat aaaattaaaa ctattgtttt acaataatag catcctttct acacagataa
      421 agagaaagcg gtgctatttt ttgcgctttt ataacaacta aggatacaag acacataact
      481 tcaacaatat cctcatctaa acctattgat ttcctaagtt caattttaaa cacaaagttt
      541 atttgtaaag atgcacacct ataaaaatct taatcatcga aatgtcacaa acatctccat
      601 attaaaaact taaatagtgc attccattta aactaaacat cgatattcct accaaaatag
      661 atttagtaat tcaaatgata ttacatcact ttcataaaat aactacaacc atcataatac
      721 ttttcaaatc tcgtcaaatt aaagtaaata cagcacaaat taacattttt aaatttataa
      781 aataaaacaa gatactcaat aatctgtagt atcttgtttt ggaataatgt aattttatat
      841 catcaacggc ttcaaatgag cagtttcata tataaataaa cacaactact caactgaact
      901 tgattaatta ataaatgatt tgccagatga catataacag cattattaga ttaattctaa
      961 tagtttattt aaattttctt cggttgtcgc ccagctggtt gcgaatctaa caacacgatg
     1021 ttgatcatcg tatttttccc aaacagcaaa tttaactttt tgttctaact ctgctatttt
     1081 ctcgttactt aaaataaaaa attgttgatt ggttggagaa tcaaagtaaa gacgatagcc
     1141 tttattttta aacccgtctt tcatcttatt tgccatttcg atagcatgtc tgcttatatt
     1201 aaaatataaa ttgtccgtaa ataattctaa aaattgtatg cctgttaacc gtccttttgc
     1261 taaaagggca ccgtgatgct tgattcgagt ggtaaattgt ttcggttcat tatttttcgt
     1321 aaaaacaatg gcttccccgc ataatgcacc tatcttcgta ccacctatat aaaatacatc
     1381 acaatattta gcgatgtctt taatagtcat atctgattgg tcactcatca atccataccc
     1441 taatcgtgca ccatccataa ataatggaag ctgatattgc ttacatactt tgcataactc
     1501 ttccaattct gatttagagt ataatgtgcc atattctgta ggatgagaaa tatataccat
     1561 tcctgggaat accatatggt cctttttaaa atcactttta aatgtctcca tgtaagtttc
     1621 aacatctgaa gcactaactt ttccttcctt agagggtata gtaattactt tatgtccact
     1681 atattcaatt gcaccgccct catgcacagc aacatgacca gtgtctgctg aaataacccc
     1741 ttcgtaactt tctaacattg aattaataac aacctgattg gtttgcgttc cacctactaa
     1801 aaaacggata gtagcatttg gacagtcaat tgtatcctta atcttttcaa ttgcctgatt
     1861 tgtgaattga tcaaagccat atcccgaagc ttgtacaaga tttgtatcta ctaatctttt
     1921 taatactttt tcatgagcgc cttctaaata atcattttca aatgaaatca ctacatttcc
     1981 ccctaaaact aatatcaaca ttttaataag ataaaccaat ttcaaaacta gttcgatatt
     2041 taaaatgtat tatgaatggt taaagtttgt atcgcattat cgcgaagttg aataaatata
     2101 ttatacatca aacaatacat taataaaatt aattaatttt taatcatagc gacttttcgt
     2161 gctggaacac atatattaat gattgaattt tactgttaaa agttctatga tttaggaaat
     2221 agagaaaaga ggggattta
//
LOCUS       DAPSKH010000127         2227 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.131, whole genome shotgun sequence.
ACCESSION   DAPSKH010000127 DAPSKH010000000
VERSION     DAPSKH010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2227)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2227)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2227
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.131"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            242..1018
                     /gene="seg"
                     /locus_tag="RPH49_002654"
     CDS             242..1018
                     /gene="seg"
                     /locus_tag="RPH49_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type G"
                     /protein_id="HDY5125762.1"
                     /translation="MKKLSTVIIILILEIVFHNMNYVNAQPDPKLDELNKVSDYKNNK
                     GTMGNVMNLYTSPPVEGRGVINSRQFLSHDLIFPIEYKSYNEVKTELENTELANNYKD
                     KKVDIFGVPYFYTCIIPKSEPDINQNFGGCCMYGGLTFNSSENERDKLITVQVTIDNR
                     QSLGFTITTNKNMVTIQELDYKARHWLTKEKKLYEFDGSAFESGYIKFTEKNNTSFWF
                     DLFPKKELVPFVPYKFLNIYGDNKVVDSKSIKMEVFLNTH"
     gene            complement(1570..>2227)
                     /locus_tag="RPH49_002655"
     CDS             complement(1570..>2227)
                     /locus_tag="RPH49_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001561168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1828 domain-containing protein"
                     /protein_id="HDY5125763.1"
                     /translation="FIRIYADTLPNNEICLSDDGLTINELEMLGIDINTKTRTKLIQN
                     ILNQFNLKLVDKEITADVKNESFAQSKHNLIQGILKIYDLTLTTKSNVTNIFYEEVFE
                     FLYDQEIRGLAQVSVSGESGLKYSIDYIVSETKSQPEKLVNFTNNLNFNKITNEAYIY
                     RDIKPNRPSRNKLEPIMLIIVNDVDHPINERAQTVAEHENLEILKWSNKSKIIETLTS
                     "
BASE COUNT          781 a          257 c          333 g          856 t
ORIGIN      
        1 atatgagagg aaaatgattt gaattgtagt aaaatttgaa atttatatat tatcttgaat
       61 acggattcaa aattatttgt tgtaattagt aataatgata aatagaattt taatttattc
      121 tgctagtgaa tttttagttt taaaacaatg ctatcgacac actacaacct gaactatcta
      181 taagcgtgaa tttataataa ggttcattgt caaatagact gaataagtta gaggaggttt
      241 tatgaagaaa ttatctactg taattattat tttgattcta gaaatagttt ttcataatat
      301 gaattatgtg aatgctcaac ccgatcctaa attagacgaa ctaaataaag taagtgatta
      361 taaaaataat aagggaacta tgggtaatgt aatgaatctt tatacgtctc cacctgttga
      421 aggaagagga gttattaatt ctagacagtt tttatctcat gatttaattt ttccaattga
      481 gtataagagt tataatgagg ttaaaactga attagaaaat acagaattag ctaacaatta
      541 taaagataaa aaagtagaca tttttggcgt tccatatttt tatacatgta taatacctaa
      601 atctgaaccg gatataaacc aaaattttgg aggttgttgt atgtatggtg gtcttacatt
      661 taatagttca gaaaatgaaa gagataaatt aattactgta caggtaacaa tcgacaatag
      721 acaatcactt ggatttacaa taactacaaa taagaatatg gttactattc aggaactaga
      781 ttacaaagca agacactggc tcactaaaga aaaaaagcta tacgagtttg atggttctgc
      841 atttgaatct ggatatataa aatttactga aaagaacaat acaagttttt ggtttgactt
      901 atttcctaaa aaagaactag taccttttgt tccatataag tttttaaata tttacggaga
      961 taataaagtt gttgattcta agagtattaa aatggaagta tttcttaata ctcactgata
     1021 agtatatttg atatcactat acaatcataa agtgcgtttt tcgaactttt gttctaagtg
     1081 ttttatagat tcatgtaaat agttagttta ttgccggtta aattatttaa tttttctaaa
     1141 tgatttattc taaatatgtt ttatgtcaat agcggtttaa aaatgctgtt ttatggcggt
     1201 ttgaaaatga cgtgctttta aatgtatttt tacttttata atcttttagt cgacatgatt
     1261 ctccagtgga aatgataatt taataacgta catttatgat tgtttaagaa tgtacaattt
     1321 tttaacactc tagaggtaaa tctatctagg taatccgaat tctccgttaa tttaacggaa
     1381 atacaatgaa ttgttagttt tcttaaaaga gcaagtgtca aatacgtatc aagaaaaagt
     1441 ttttctgact ctttgacctt gttctttttt gttctaaaat aaaacgtgca aataaaaaag
     1501 ttatctgctt ttctatttgc acgatatggt ttggaaatta aagaatataa ataagggact
     1561 actgctaatt tatgaggtta aagtttcaat gatttttgat ttattagacc attttaatat
     1621 ctcaaggttt tcatgttctg ctacagtttg tgctctttca tttatcggat gatctacatc
     1681 atttacaatt atcaacatga taggttctaa tttgtttctg gatggtctgt ttggtttgat
     1741 atcacggtaa atataagctt cattagttat tttgttgaaa tttaagttgt ttgtaaagtt
     1801 aactagtttt tctggttgtg attttgtttc agaaacaata taatcaatag aatattttaa
     1861 acctgattct ccagaaacag aaacttgtgc taaacctctt atttcttggt catataagaa
     1921 ttcaaatact tcttcataga atatgtttgt aacgttagat ttagtagtta aagtaaggtc
     1981 ataaattttc aatatgcctt gaattaaatt atgtttagac tgagcaaaac tctcattttt
     2041 aacatccgct gtaatttctt tatcaactaa ttttaaatta aattgattta aaatattttg
     2101 tataagttta gttctcgttt ttgtgtttat atcaataccc aacatttcta attcattaat
     2161 cgtcaatccg tcatctgata gacaaatttc attattaggt agtgtatcag catatattct
     2221 aataaaa
//
LOCUS       DAPSKH010000128         2165 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPSKH010000128 DAPSKH010000000
VERSION     DAPSKH010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2165)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2165)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2165
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.132"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(158..256)
                     /locus_tag="RPH49_002656"
                     /pseudo
     CDS             complement(158..256)
                     /locus_tag="RPH49_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429703.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="head morphogenesis protein"
     gene            complement(232..339)
                     /locus_tag="RPH49_002657"
     CDS             complement(232..339)
                     /locus_tag="RPH49_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125764.1"
                     /translation="MCPKRADDILKASMEYQSTDYKRRYISWKTMIAMK"
     gene            complement(414..1700)
                     /gene="ltrA"
                     /locus_tag="RPH49_002658"
     CDS             complement(414..1700)
                     /gene="ltrA"
                     /locus_tag="RPH49_002658"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020219999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDY5125765.1"
                     /translation="MYRESPSMMELVVREHNIQKAIKKVKKNKGAPGIDGMKVSEIQG
                     HFAQYFPKIKQKLLEGTYKPQAVKKVEIPKANGKKRVLGIPVVRDRVIQQAIKQVIEP
                     SIDRTFSKHSHGFRPNRSTGTALKECASYYEAGYTIAVDCDLKQCFDNINHDKLMYLF
                     ERHIKDKAVSTFIRRRLQVGAIDLSGEVAERKIGAPQGGVISPLLCNIYLHELDKELE
                     KRNHRFVRYADDFVIFVKTKRAGERVMDSIKTFIHKTLKLEVNNDKSKVGSPTRLKFL
                     SCLMSKVNGTYRFRPTTEAKRNLKRNLKWLTRRSRPGSFQDIITEINRVTRGWINYFG
                     KGFIKRFLKELEPWLNRRIRQLILKRWKKIKTKYKMLRKYGLDHDSAMRIASSRKKYW
                     RLSSTHEVHRALTTKRLRKWGLLSLTQLAETAYARY"
BASE COUNT          542 a          463 c          362 g          798 t
ORIGIN      
        1 ttacttgtcc cttattagta acgattgtca ttgattttat tgatggatgc ttaaaaaatg
       61 taaataaatc atattctgaa aatcctgact gtccaggatg gttatgtaac ataacaattg
      121 aattcagttt actgttaaat aataattcgg ttgcttgtta ccctggcaca aaagatacac
      181 tatcttgatt gacatatact tttgtaaatt taccatcttt taacaaataa gctacttcat
      241 tgctatcatt gttttccatg agatatacct ccgtttatag tctgtcgact gatattccat
      301 acttgctttt aaaatgtcat cagcacgttt tggacaaatc gagtaggaga ataatcatta
      361 cttgattatt cgtcctctca caccaccgag cgtacggttc cgtactcggc ggttcaatat
      421 cttgcgtaag ccgtctctgc gagttgggtt agtgataata acccccactt gcggagacgt
      481 tttgttgtaa gtgcacgatg aacctcatgc gtagatgata aacgccagta tttctttctt
      541 gagctcgcga ttctcattgc gctatcgtgg tctagaccat acttgcgcaa catcttatat
      601 tttgttttaa tcttcttcca tcttttgagt atgagttgcc taatgcggcg atttagccaa
      661 ggttctaatt ctttaagaaa tctttttatg aatccttttc caaaatagtt aatccatcct
      721 cgtgtcacac gattaatttc tgttataata tcttggaatg aacctggtct acttcgtctg
      781 gttaaccact ttaagttgcg ttttaaattt ctttttgctt ccgtagtggg tctgaaacga
      841 taagtgccat ttactttgct cattagacaa ctcaagaact ttaaacgggt aggagaaccc
      901 accttacttt tatcattatt gacttcaagt ttgagggttt tgtgtatgaa tgttttaata
      961 ctatccatca cacgttcacc tgcacgtttc gtcttgacaa agatgacgaa gtcatctgca
     1021 tatctcacaa aacgatgatt acgtttttcg agctctttat ccagttcatg tagatatatg
     1081 ttacagagta atggtgatat cacaccacct tgcggtgcac ctatctttct ttctgcgact
     1141 tcgccagata ggtcaatggc accaacttgt aaccttctac ggataaatgt cgataccgct
     1201 ttatctttaa tgtggcgctc aaataaatac atgagtttat catgatttat gttgtcaaag
     1261 cattgtttta aatcacaatc tacggctatc gtgtaacctg cttcatagta agacgcacat
     1321 tctttcagtg ctgttcctgt actacgatta ggtctaaagc catgactgtg tttagagaag
     1381 gtacgatcga tactaggttc aatcacttgt ttaattgctt gttgtatcac tctgtctctt
     1441 acgacaggta taccaagcac acgctttttc ccatttgctt tgggaatttc aactttctta
     1501 actgcttgag gtttgtatgt accttcaagc agtttttgtt ttatttttgg aaagtattgc
     1561 gcaaagtgac cttgtatttc actcactttc atgccatcaa tgccaggggc acctttattc
     1621 tttttaactt tcttaattgc cttttgaatg ttgtgttctc ttacaacaag ctccatcatc
     1681 gatggagact cacgatacat ttctttcatt tcacctaaga tttaccatgc gcacttattt
     1741 accctttttc gttccactac ttatctctct atatgttgcc aactagttcg ttgttttctg
     1801 catgatgtaa atctataacc tccattcttt actttgtatg aatattgttc cgtccttcgg
     1861 tacattttcc ctactatgac gtctgctgac ttctcattat tcgttgttac tacggtatgt
     1921 gcaccgctaa tgagacctcc ctgggtaagg tgcaaccact ttccactcat ctcatcgcat
     1981 catttaccat ataaaattcg ggtagtattg gacttcatct tgtttagcag actcatccgt
     2041 tttatatggc cttattatga tgtttctgtt cgtcaatgcg agtgtttgcg tccgacttcc
     2101 ttcagattcc acttcacaat ggacaccctt gtctttcgct aacagttcct actaccaagc
     2161 ctgta
//
LOCUS       DAPSKH010000129         2150 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPSKH010000129 DAPSKH010000000
VERSION     DAPSKH010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2150
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.133"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            102..1337
                     /gene="istA"
                     /locus_tag="RPH49_002659"
     CDS             102..1337
                     /gene="istA"
                     /locus_tag="RPH49_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDY5125766.1"
                     /translation="MRHDIYEGVLFYIMKGIKPNYAELGRQYNCDPRTVKKYYEAGKE
                     NELERLKKRQQNKKASKLDPFKEIINKKIELGCTAMAIFKYIEKKGYEGKYTILREYC
                     KNKKQNETKKATIRVETNPGIAAQVDWKEDMVMHDKFGRTYQFNIFLYVLHYSKMKYI
                     TLTWDRKQDTLFECLKDAFEYTEGVPKEIWFDNMRTVVDRPRTQYKKVVFNNLFYQFS
                     KDANFEPIACRPYRPQTKGSVESLAKFVEQRLRPYDYEFYDAVELIGLVNDLCHELNH
                     LEISQATEQRPIDVFNYEEKEHLNSFNAKLLDTYIENECIRIVSKESMINFRKGKYSV
                     PTKYIGEEVQVIFNNSTDELLIYYDGELIRRHNLSERKFNYIVEDMSEILKSDVFKHK
                     DDKEILTYIENSLLLYDEI"
     gene            1349..2116
                     /gene="istB"
                     /locus_tag="RPH49_002660"
     CDS             1349..2116
                     /gene="istB"
                     /locus_tag="RPH49_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HDY5125767.1"
                     /translation="MNTNHQKLLNNFEILKLKKFKDYYPNYIELLSKNEKSLTEILID
                     LTEKEIEYQSELKFKRAVNSARFPKIKYLHDFDFMFQPSINQQEILTLKSMHFLEDSI
                     NICFLGNSGVGKTHLAISLGIEACKQNIKTRFYTFKELIDLLTVSDSKGIINKTLKQL
                     SRIELLIIDEIGYTPITKEQADLFYQLMSLRYEWKSTIITTNIPFSSWGESFSNKIVS
                     AAIIDRLVHHSKVFKITGESYRLKDYKTEKSLNIRQS"
BASE COUNT          868 a          287 c          331 g          664 t
ORIGIN      
        1 gtaggaaaat ggcgaaatga aaatgctgtt tttcctacat tttttctttt ttaaattata
       61 taatcatgtc ttaactcaat cttcgattgg aggttatttg attgagacat gacatttatg
      121 aaggagtgct attttacatt atgaaaggta ttaaaccaaa ttatgccgag cttggtcgac
      181 aatataattg tgatccaaga acagttaaaa aatattatga agcaggaaaa gaaaatgaat
      241 tagaacgatt gaagaaaaga caacaaaata agaaagcatc aaaactagat ccatttaaag
      301 aaattattaa taaaaaaatt gaattaggat gtacagctat ggccattttt aaatatatag
      361 agaaaaaggg ttatgaaggt aaatatacta ttctacgaga atactgtaaa aataaaaaac
      421 aaaatgagac taaaaaagca actatacgcg tagaaactaa tcccggtata gctgctcaag
      481 tagactggaa agaagatatg gtaatgcatg ataagtttgg cagaacttat caattcaaca
      541 tctttcttta cgttctacac tattcaaaaa tgaagtatat cacattaact tgggatagaa
      601 aacaagatac cttatttgaa tgtttaaaag acgcttttga atacaccgaa ggggttccaa
      661 aagaaatctg gttcgataat atgagaactg tagttgatcg acctagaaca caatataaaa
      721 aagtcgtctt taataattta ttttatcaat ttagtaagga tgccaacttt gaacctattg
      781 cttgtagacc ctatcgtcct caaacaaaag ggtctgttga atcattagct aaatttgttg
      841 aacagcgttt aagaccatac gattatgaat tttatgatgc tgtagaactt attgggctag
      901 taaacgattt atgtcacgaa ttgaatcact tagaaatttc acaagcaaca gaacaacgac
      961 ctatcgacgt tttcaattat gaagaaaaag aacatttaaa ttcttttaat gccaagttac
     1021 tagatactta catcgaaaat gagtgtataa gaatcgtttc taaagaatcg atgattaact
     1081 ttagaaaagg taaatactcg gtacctacta aatacattgg tgaagaagta caagtgatat
     1141 tcaataattc tactgatgaa ttgctgattt attatgatgg tgaattaata agacggcata
     1201 atctatccga aagaaaattt aattatatcg ttgaagatat gagtgaaata ttaaaatcag
     1261 atgtatttaa acataaggat gacaaagaaa ttcttacgta tatagaaaat tcattattac
     1321 tgtatgacga aatttaggag gactttcgat gaatacgaac catcaaaaat tacttaataa
     1381 ctttgaaata ttaaaactaa aaaaattcaa agattattat ccaaactata ttgaattact
     1441 ttctaaaaat gagaaatctt taactgaaat attgattgat ttaacggaaa aagaaataga
     1501 atatcaatca gaattaaaat ttaaacgtgc tgtgaattca gcacgtttcc ctaaaataaa
     1561 atatttacat gattttgatt tcatgtttca acctagtata aatcaacaag aaatactcac
     1621 tttaaaatct atgcattttt tagaagatag tataaatatt tgtttcttag gtaatagtgg
     1681 tgttggtaaa acacacctag caatctcatt aggaatagag gcatgtaagc aaaatataaa
     1741 gactagattc tatactttca aagaattaat agacttatta actgtctcag attccaaagg
     1801 aatcattaat aaaacattaa agcaattaag cagaatagag ttacttatca ttgatgaaat
     1861 tggttatact cccatcacca aagaacaagc tgatttattc taccagttaa tgtcactaag
     1921 gtatgagtgg aaatcaacaa taattacgac taatattcca ttttcgagtt ggggagagtc
     1981 atttagtaat aagattgtat cagcagctat aattgatcgg ttagttcacc attcaaaagt
     2041 atttaaaatt actggagaat catatcgatt aaaagattat aaaaccgaaa aatcattaaa
     2101 tatacgacaa tcttaaaccg ctaaaaaacg acattttcaa accgccataa
//
LOCUS       DAPSKH010000130         2042 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPSKH010000130 DAPSKH010000000
VERSION     DAPSKH010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 2042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2042
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.134"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..399
                     /locus_tag="RPH49_002661"
     CDS             <1..399
                     /locus_tag="RPH49_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding protein"
                     /protein_id="HDY5125768.1"
                     /translation="GPREKKPVSINHNIVEYNDGTFKYQSRPKFNSTPKYIKFRHDYN
                     IVEYNDGTFGYGPRPHFNKPAAKTDATIKKEQKLIQAQNLVREFEKTHTVSAHRKAQK
                     AVNLVSFEYNVKKMILQERIDEVLKQGLVR"
     gene            551..901
                     /locus_tag="RPH49_002662"
     CDS             551..901
                     /locus_tag="RPH49_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN family protein"
                     /protein_id="HDY5125769.1"
                     /translation="MKIKKYIVAGTLAVLLSTTAVSTLNGNKAEASSYDNYLTQSKYH
                     DKKIAEELKSLLRQSNVYDLAAGSLNRYYKRTIMMNEYRAKAALKKNDFKSMAEAKVG
                     LENIYKEIDEIINR"
     gene            complement(1154..1339)
                     /locus_tag="RPH49_002663"
     CDS             complement(1154..1339)
                     /locus_tag="RPH49_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125770.1"
                     /translation="MNKHINKKTTKHLEDYKKVQQRNSEETNRGCLKSVAMLIVLFLF
                     IIFGIVACSTHVNFFFQ"
BASE COUNT          819 a          254 c          302 g          667 t
ORIGIN      
        1 ggtccaagag aaaagaaacc agtgagtatt aatcacaata tcgtagagta caatgatggt
       61 acttttaaat atcaatctag accaaaattt aactcaacac ctaaatatat taagtttaga
      121 catgattata acattgtgga atataatgac ggtacatttg gatatggacc acgtccgcat
      181 tttaataaac cagcagcgaa aactgatgca actataaaaa aagaacaaaa attgattcaa
      241 gctcaaaatc ttgtgagaga atttgaaaag acccatactg tgagcgcaca tagaaaagca
      301 caaaaggcag tcaacttagt atcatttgaa tacaatgtta agaaaatgat attgcaagag
      361 cgaattgatg aagtattaaa gcaaggatta gtgagataat acttctgtca ttattataag
      421 ttcaaaataa tttaatctaa tattaatttc tattaataaa aagactatgc tatttaatag
      481 taggttaatg taactttcct aaaattgact atataatcat taagtatcaa tttttaaagg
      541 agaatttaca atgaaaatta aaaaatatat agtagcagga acattagcag tactattatc
      601 aacaacagca gtatcaacgt taaacgggaa caaagcagaa gcaagtagtt atgacaatta
      661 tttaactcaa agtaaatatc acgataaaaa aattgctgaa gagttgaaat cactacttag
      721 acaatcgaac gtatatgact tggctgcagg tagcttaaat cgatattaca aacgtacgat
      781 tatgatgaat gaatatagag caaaagcagc actaaagaaa aatgatttca aatcaatggc
      841 tgaagctaaa gttggattag aaaacattta caaagaaatt gatgaaatta taaatagata
      901 ataaagaaaa caggttgaga caataaatat cattgtcttc gcctgttttt taatttgtat
      961 agttaaaaat tctacaattt aatatttatg tatgagcaat gaatatacaa taatagggga
     1021 gactaataca aatataatag ttagaaatgt tatgcacaaa attgctttgt acaatctaaa
     1081 aaatatttat aatgctccca tagataaaat caaatgctgt aagaaacgta gtgaatatta
     1141 ctcaatcagc atattattgg aagaaaaagt taacgtgtgt agaacatgcc acaataccaa
     1201 atataatgaa taaaaataag acgataagca tggcgacact ttttaaacaa cctctatttg
     1261 tttcttccga atttctttgt tgaacctttt tataatcttc aagatgcttt gtggtctttt
     1321 tatttatatg tttattcatg atgtttactc cttaatctaa atgtaaattg cattaaaata
     1381 gttgaaaaca taccttgaaa taaagatata aagctaaagt tgagaagagt gttattttaa
     1441 atttaagcaa aattaactgt aaataagtta atttgatgat aacatgtttc gcttattttt
     1501 aaaattgata gtttttaaac tgacgcatta aaatattaat gaaacactag aacacataaa
     1561 tgaataataa aggtgcgcag tatagaatta ttaatgcaac actaagtata aatattgtta
     1621 actgtaaact atctttagtt ttaatataaa caattaagat aagcagtgtt aaaagaacca
     1681 tatatattaa tgacgaagat gtccatacaa aatctgcgtc tgtcgtagtt aacagcggta
     1741 ctataattag tccgaagtta atcatgcatg ctatatatac aatgatgtta tacacaatgt
     1801 taatttttgg tcaccacctt agctgttata ttttaaatgc ttggaaatcg tgcattttta
     1861 agtgtaatga ttatctgaat ctttgattac cgtttgtttt tcgtttaaaa gactatatat
     1921 agtatgcctt tatatttcta aatgtttttt aatatttaat tctcgtcaat atttggatta
     1981 tgaatcatca attcaagtac tttgttagat gagtcaattg taaattcaga tccatagtta
     2041 ac
//
LOCUS       DAPSKH010000131         1992 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPSKH010000131 DAPSKH010000000
VERSION     DAPSKH010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1992
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.135"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..641)
                     /locus_tag="RPH49_002664"
     CDS             complement(<1..641)
                     /locus_tag="RPH49_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDY5125771.1"
                     /translation="MSQNTNHSYFQQNQHAQSISKVWLYFMYYWIIFGIGCYLGQFLP
                     LSWRQPLSFGLLIIILATLVFERARRFGLIISHIYAVVIGLLSYATFTTYLQNLGPDI
                     FYKNIALAIFAFIAFGIIGYFFVGDASSIGKYLFVTLITLIIASLIGIFLHNPIFYTV
                     ITVVSLLLFLLYTLYDFNRLKRGDYSPREMGFNLFINLLNIIKDILYLANMFR"
     gene            1002..1799
                     /locus_tag="RPH49_002665"
     CDS             1002..1799
                     /locus_tag="RPH49_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDY5125772.1"
                     /translation="MKKLAFAITATSGAAAFLTHHDAQASTQHTVQSGESLWSIAQKY
                     NTSVESIKQNNQLDNNLVFPGQVISVGGSDAQNTSNTSPQAGSASSHTVQAGESLNII
                     ASRYGVSVDQLMAANNLRGYLIMPNQTLQIPNGGSGGTTPTATTGSNGNASSFNHQNL
                     YTAGQCTWYVFDRRAQAGSPISTYWSDAKYWAGNAANDGYQVNNTPSVGSIMQSTPGP
                     YGHVAYVERVNGDGSILISEMNYTYGPYNMNYRTIPASEVSSYAFIH"
BASE COUNT          746 a          337 c          284 g          625 t
ORIGIN      
        1 cttctgaaca tattagcaag ataaagtata tccttaataa tattcaacaa attaataaat
       61 agattaaatc ccatttctct tggtgaatag tcacctcttt ttaaacgatt aaaatcatac
      121 aaagtataaa gtagaaataa caacagacta acgacggtaa taacagtata aaaaatagga
      181 ttatgcagaa aaataccaat tagactcgca ataattaaag ttattaatgt aacgaataaa
      241 tacttaccta tacttgatgc atctccaacg aagaaataac caataatacc aaatgctata
      301 aatgcaaaaa ttgctaatgc gatattttta tagaaaatat ctggtcctaa attttgtaaa
      361 tacgtggtaa acgttgcgta tgacaataag ccaattacta cagcgtaaat atgtgaaatg
      421 attaaaccga accgtctcgc tctctcaaat acaagtgttg ctaaaataat aatcagtaat
      481 ccaaatgaca agggttgtcg ccaacttaat ggtaaaaact gacctagata gcatcctatg
      541 ccaaatataa tccagtaata cataaaataa agccacactt tacttattga ttgagcatgc
      601 tggttttgct gaaaatatga atgatttgta ttttgcgaca aaataattcc tccttctact
      661 gtcgttttat gcgtcaaatt ttacagtaaa ttttgcttca tcaaaagaaa taacctttaa
      721 caagtacagt aattttacat tttacaatgt tacaaaatat aaatttttat aattagttaa
      781 aatcactaaa acgcttttat acactatcaa atcagcattt ataaaaatat gaaccgatat
      841 cctaaaatgt taataatatt acaagataat aacaaaccac acaaagctac ttatttttga
      901 taatatggaa agcgtaatat aaaacgaaaa cttaatttac tatataaatt gtcttaataa
      961 tttttaaaag tagtaaatct taattttaag gaggagtccc tttgaaaaaa ttagcatttg
     1021 caataacagc aacatctggt gcagctgcat ttttaacgca tcatgatgca caagcttcta
     1081 cacaacatac agtacaatct ggtgaatcat tatggagtat tgctcaaaaa tacaacactt
     1141 cagtagagag tattaaacaa aataaccaat tagataacaa cttggtattc cctggtcaag
     1201 ttatctcagt aggtggaagt gatgcacaaa atacgtcaaa cacttctcca caagctggtt
     1261 cagcatcatc tcatactgta caagctggtg aatcattaaa tatcattgct agcagatatg
     1321 gtgtttcagt tgatcaatta atggcagcca ataacttacg tggttattta attatgccta
     1381 accaaacatt acaaattcct aatggtggat caggtggtac aacaccaaca gctacaacag
     1441 gtagcaatgg caatgcatca tcttttaatc accaaaattt atacactgct ggtcaatgta
     1501 catggtacgt gtttgaccgt cgtgctcaag ctggtagtcc aattagcaca tattggtcag
     1561 acgctaagta ttgggctggt aacgcagcta atgatggtta ccaagtaaac aacacaccat
     1621 cagttggttc aattatgcaa agcacacctg gcccatatgg tcatgttgct tatgttgaac
     1681 gtgtcaatgg tgatggtagt atcttgattt ctgaaatgaa ttacacatat ggtccataca
     1741 atatgaacta ccgtacaatt ccagcttcag aagtttctag ctatgcattc atccattaat
     1801 taaataaatt gtactgatat atactagcaa ttcacatcat gtgagattgc tagtttttta
     1861 tttttgaaaa aaattttcat tttggtacaa aaaattatct cacccttccc tatcatactt
     1921 atttatattt tgtatgaatg gtagttaggt aaaaaataat aacctaccta tttgattaaa
     1981 ttaaatgcat aa
//
LOCUS       DAPSKH010000132         1965 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPSKH010000132 DAPSKH010000000
VERSION     DAPSKH010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1965)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1965)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1965
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.136"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>1965
                     /locus_tag="RPH49_002666"
     rRNA            <1..>1965
                     /locus_tag="RPH49_002666"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          553 a          394 c          582 g          436 t
ORIGIN      
        1 tcgattccct tagtagcggc gagcgaaacg ggaagagccc aaaccaacaa gcttgcttgt
       61 tggggttgta ggacactcta tacggagtta caaaggacga cattagacga atcatctgga
      121 aagatgaatc aaagaaggta ataatcctgt agtcgaaaat gttgtctctc ttgagtggat
      181 cctgagtacg acggagcacg tgaaattccg tcggaatctg ggaggaccat ctcctaaggc
      241 taaatactct ctagtgaccg atagtgaacc agtaccgtga gggaaaggtg aaaagcaccc
      301 cggaagggga gtgaaataga acctgaaacc gtgtgcttac aagtagtcag agcccgttaa
      361 tgggtgatgg cgtgcctttt gtagaatgaa ccggcgagtt acgatttgat gcaaggttaa
      421 gcagtaaatg tggagccgta gcgaaagcga gtctgaatag ggcgtttagt atttggtcgt
      481 agacccgaaa ccaggtgatc tacccttggt caggttgaag ttcaggtaac actgaatgga
      541 ggaccgaacc gacttacgtt gaaaagtgag cggatgaact gagggtagcg gagaaattcc
      601 aatcgaacct ggagatagct ggttctctcc gaaatagctt tagggctagc ctcaagtgat
      661 gattattgga ggtagagcac tgtttggacg aggggcccct ctcgggttac cgaattcaga
      721 caaactccga atgccaatta atttaacttg ggagtcagaa catgggtgat aaggtccgtg
      781 ttcgaaaggg aaacagccca gaccaccagc taaggtccca aaatatatgt taagtggaaa
      841 aggatgtggc gttgcccaga caactaggat gttggcttag aagcagccat catttaaaga
      901 gtgcgtaata gctcactagt cgagtgacac tgcgccgaaa atgtaccggg gctaaacata
      961 ttaccgaagc tgtggattgt cctttggaca atggtaggag agcgttctaa gggcgttgaa
     1021 gcatgatcgt aaggacatgt ggagcgctta gaagtgagaa tgccggtgtg agtagcgaaa
     1081 gacgggtgag aatcccgtcc accgattgac taaggtttcc agaggaaggc tcgtccgctc
     1141 tgggttagtc gggtcctaag ctgaggccga caggcgtagg cgatggataa caggttgata
     1201 ttcctgtacc acctataatc gttttaatcg atggggggac gcagtaggat aggcgaagcg
     1261 tgcgattgga ttgcacgtct aagcagtaag gctgagtatt aggcaaatcc ggtactcgtt
     1321 aaggctgagc tgtgatgggg agaagacatt gtgtcttcga gtcgttgatt tcacactgcc
     1381 gagaaaagcc tctagataga aaataggtgc ccgtaccgca aaccgacaca ggtagtcaag
     1441 atgagaattc taaggtgagc gagcgaactc tcgttaagga actcggcaaa atgaccccgt
     1501 aacttcggga gaaggggtgc tctttagggt taacgcccag aagagccgca gtgaataggc
     1561 ccaagcgact gtttatcaaa aacacaggtc tctgctaaac cgtaaggtga tgtatagggg
     1621 ctgacgcctg cccggtgctg gaaggttaag aggagtggtt agcttctgcg aagctacgaa
     1681 tcgaagcccc agtaaacggc ggccgtaact ataacggtcc taaggtagcg aaattccttg
     1741 tcgggtaagt tccgacccgc acgaaaggcg taacgatttg ggcactgtct caacgagaga
     1801 ctcggtgaaa tcatagtacc tgtgaagatg caggttaccc gcgacaggac ggaaagaccc
     1861 cgtggagctt tactgtagcc tgatattgaa attcggcaca gcttgtacag gataggtagg
     1921 agcctttgaa acgtgagcgc tagcttacgt ggaggcgctg gtggg
//
LOCUS       DAPSKH010000133         1943 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPSKH010000133 DAPSKH010000000
VERSION     DAPSKH010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1943
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.137"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            57..1013
                     /locus_tag="RPH49_002667"
     CDS             57..1013
                     /locus_tag="RPH49_002667"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDY5125773.1"
                     /translation="MYNPFDEAYHGLCEEILEIGNRRDDRTHTGTISKFGHQLRFDLT
                     KGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYVQSDDYHGP
                     DMTDFGHRSQQDPEFNEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKN
                     GNHYDQLKSVIQQIKTNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQL
                     YQRSADIFLGVPFNIASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLS
                     RDSYLPPQLKINTDKSIFDINYEDLELINYESHPAIKAPIAV"
     gene            1055..1540
                     /gene="dfrC"
                     /locus_tag="RPH49_002668"
     CDS             1055..1540
                     /gene="dfrC"
                     /locus_tag="RPH49_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrC"
                     /protein_id="HDY5125774.1"
                     /translation="MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHIKQLTTGNTLVMA
                     RKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLYEAM
                     IDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKG
                     K"
     gene            1550..>1943
                     /locus_tag="RPH49_002669"
     CDS             1550..>1943
                     /locus_tag="RPH49_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDY5125775.1"
                     /translation="MAKQIIVTDSTSDLSHEYLKQHNIHVIPLSLTIDGKSYTDQVDI
                     SSSEYIDHIENDADVKTSQPPIGRFIETYEQLAQDDVEIISIHLSSGLSGTYNTAVQA
                     SHMVDGNITVIDSKSISFGLGYQIKQIVE"
BASE COUNT          708 a          308 c          334 g          593 t
ORIGIN      
        1 cttttctagt ataatgttta ttaatatagt acatattttt ataaggagtt gtacgcatgt
       61 ataatccatt cgacgaagct tatcatggct tatgcgaaga gatattagaa atagggaata
      121 gacgcgatga tcgcacacat accgggacaa tttccaaatt tgggcatcaa ttgcgtttcg
      181 atttaaccaa agggtttcct ttacttacaa ccaaaaaggt ttcttttaaa ttagtagcaa
      241 ctgaattatt atggtttatt aaaggagata caaacattca atacctactt aaatataata
      301 acaatatatg gaatgaatgg gcatttgaaa attatgttca gtctgatgat tatcatggac
      361 cagacatgac agattttgga catcgttccc agcaagaccc tgaatttaac gagcagtata
      421 aagaagaaat gaaaaaattt aaagaacgta ttctaaacga tgatgcattt gctaaaaaat
      481 atggcaactt agggaatgtt tatggtaaac aatggagaga ttgggaagat aaaaatggaa
      541 atcattacga tcaattaaaa tcagttatac aacaaattaa aaccaatcca aactctcgac
      601 gtcacattgt ttcagcatgg aatcctactg aaatcgattc aatggcatta ccaccttgcc
      661 acacaatgtt tcaattttac gtacaagagg gtaaattaaa ttgtcaatta tatcaaagaa
      721 gtgctgatat atttttaggt gttcctttca atattgcaag ttatgcttta ctgacacatc
      781 ttgttgcaaa agaatgtgga cttgaggtgg gtgaattcat tcatacattt ggagatgcac
      841 atatttattc caatcatatg gatgcaatac atacacaatt atcaagagat agttatctac
      901 cacctcaatt aaaaattaat acagataaat caatttttga tattaattat gaagatttag
      961 aattgataaa ttatgaatca caccctgcta ttaaagcacc tattgcggta taaaaagatg
     1021 cattaatatt tcgcatacag aaaggaggta taccatgaca ttatcaataa ttgtcgctca
     1081 cgataaacaa agagtcattg ggtaccaaaa tcaattacct tggcacttac caaatgattt
     1141 aaagcatatt aaacaactga ccactgggaa tacacttgta atggcacgga aaacttttaa
     1201 ttctataggg aagccattgc caaatagacg taacgtcgta ctcactaacc aagcttcatt
     1261 tcaccatgaa ggggtagatg ttataaactc tcttgatgaa attaaagagt tatctggtca
     1321 tgtttttata tttggaggac aaacgttata cgaagcaatg attgaccagg tagatgatat
     1381 gtatatcaca gtaatagatg gaaagtttca aggagacaca ttctttccac catacacatt
     1441 cgaaaactgg gaagtcgaat cttcagtaga aggtcaacta gatgaaaaaa atactatacc
     1501 gcatacattc ttacatttag tgcgtagaaa agggaaatag gaggcaatta tggctaaaca
     1561 aattatcgtc acggattcaa cctctgattt atcacatgaa tatttaaaac aacataacat
     1621 tcatgttata ccattaagcc tgacaatcga cgggaaatct tacactgatc aagttgatat
     1681 ctcttcaagt gagtatatcg atcatattga aaatgatgca gacgtcaaaa caagtcaacc
     1741 acctattggt cgatttattg aaacatatga gcaattagct caagatgacg ttgaaattat
     1801 aagtattcat ctttcgtcag gcttaagtgg tacttataat actgctgttc aagcgagcca
     1861 tatggtagat ggtaatatta cagtgattga ttctaaatct atttcgtttg ggttaggtta
     1921 tcaaattaag caaattgttg aat
//
LOCUS       DAPSKH010000134         1841 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPSKH010000134 DAPSKH010000000
VERSION     DAPSKH010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1841
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.138"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            180..974
                     /gene="tagH"
                     /locus_tag="RPH49_002670"
     CDS             180..974
                     /gene="tagH"
                     /locus_tag="RPH49_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acids export ABC transporter
                     ATP-binding subunit TagH"
                     /protein_id="HDY5125776.1"
                     /translation="MNVSVNIKNVTKEYRIYRTNKERMKDALIPKHKNKTFFALDDIS
                     LKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNGEVSVIAISAGLSGQLTG
                     IENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITV
                     NPDILVIDEALSVGDQTFAQKCLDKIYEFKEQNKTIFFVSHNLGQVRQFCTKIAWIEG
                     GKLKDYGELDDVLPKYEAFLNDFKKKSKAEQKEFRNKLDESRFVIK"
     gene            complement(1035..1799)
                     /locus_tag="RPH49_002671"
     CDS             complement(1035..1799)
                     /locus_tag="RPH49_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HDY5125777.1"
                     /translation="MTVEERSNTAKVDILGVDFDNTTMLQMVENIKTFFANQSTNNLF
                     IVTANPEIVNYATTYQAYLELINQASYIVADGTGVVKASHRLKQPLAHRIPGIELMDE
                     CLKIAHVNHQKVFLLGATNEVVEAAQYALQQRYPNISFAHHHGYIDLEDETVVKRIKL
                     FKPDYIFVGMGFPKQEEWIMTHENQFESTVMMGVGGSLEVFAGAKKRAPYIFRKLNIE
                     WIYRALIDWKRIGRLKSIPIFMYKIAKAKRKIKKAK"
BASE COUNT          607 a          308 c          297 g          629 t
ORIGIN      
        1 gttgaaataa gtttagtttt taaatatcat tgttatcatt gatgattaac attttgtgtc
       61 aaaacaccaa ctctgataat aacaaaatct tctatacact ttacaacagg ttttaaaatt
      121 taacaactgt tgagtagtat attataatct agataaatgt gaataaggaa ggtctacaaa
      181 tgaacgtttc ggtaaacatt aaaaatgtaa caaaagaata tcgtatttat cgtacaaata
      241 aagaacgtat gaaagatgcg ctcattccca aacataaaaa caaaacattt ttcgctttag
      301 atgacattag tttaaaagca tatgaaggtg acgtcatagg gcttgttggc atcaatggtt
      361 ccggcaaatc aacgttgagc aatatcattg gcggttcttt gtcgcctact gttggcaaag
      421 tggatcgtaa tggtgaagtc agcgttatcg caattagtgc tggcttgagt ggacaactta
      481 cagggattga aaatatcgaa tttaaaatgt tatgtatggg ctttaagcga aaagaaatta
      541 aagcgatgac acctaagatt attgaattta gtgaacttgg tgagtttatt tatcaaccag
      601 ttaaaaagta ttcaagtggt atgcgtgcaa aacttggttt ttcaattaat atcacagtta
      661 atccagatat cttagtcatt gacgaagctt tatctgtagg tgaccaaact tttgcacaaa
      721 aatgtttaga taaaatttac gagtttaaag agcaaaacaa aaccatcttt ttcgttagtc
      781 ataacttagg ccaagtgaga caattttgta ctaagattgc ttggattgaa ggcggaaagt
      841 taaaagatta cggtgaactt gatgatgtat tacctaaata tgaagctttc ctaaacgatt
      901 ttaaaaagaa atccaaagcc gaacaaaaag aatttagaaa caaactcgat gagtcccgct
      961 tcgttattaa ataaaccgaa aaaaccgaga atctccattt aaggatttcc tcggttttat
     1021 ttttgtcatc atgattattt cgcctttttt atttttcttt ttgctttggc tattttatac
     1081 ataaatatag gaatactctt taatctacca atacgtttcc aatctattaa tgctctatat
     1141 atccattcaa tgtttaattt tctaaagata tagggcgctc tctttttagc cccagcaaat
     1201 acttcaagag aaccacctac gcccatcatc actgtagatt caaattggtt ttcatgtgtc
     1261 ataatccatt cttcttgttt agggaatccc atacctacaa atatgtaatc aggtttaaac
     1321 agtttaattc gtttcactac tgtctcatct tccaaatcaa tataaccgtg atgatgtgca
     1381 aacgatatgt ttggatatct ttgttgtaat gcatattgtg ccgcttctac aacttcatta
     1441 gttgccccta gcaaaaatac tttttgatga tttacatgag caattttcaa acattcatcc
     1501 atcaactcaa taccaggtat acgatgcgct agaggttgct ttaaacgatg cgaagctttg
     1561 actactcctg tcccatcagc aacaatatag ctcgcttgat ttattaactc taaatacgct
     1621 tgatatgtcg tcgcgtaatt cactatttca gggttggctg ttactataaa aagattattc
     1681 gttgattgat ttgcaaaaaa ggttttaata ttttcaacca tttgcaacat tgttgtatta
     1741 tcaaaatcga cccctaaaat gtcaactttg gctgtattgg atctttcttc aacagtcata
     1801 acaggaatct cctatcttat ttcattatta tgttagtgta a
//
LOCUS       DAPSKH010000135         1827 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPSKH010000135 DAPSKH010000000
VERSION     DAPSKH010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1827)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1827)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1827
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.139"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            398..583
                     /locus_tag="RPH49_002672"
     CDS             398..583
                     /locus_tag="RPH49_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125778.1"
                     /translation="MSEYKKKIIELIESNLTGYEISKKTGVSQYVLSQLRQGKREVDN
                     LTLNTTEKLYEYANKVL"
     gene            1095..1199
                     /locus_tag="RPH49_002673"
     CDS             1095..1199
                     /locus_tag="RPH49_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125779.1"
                     /translation="MFKVNYSILSYYPEYNIAVSWQRLREGKTIKNKI"
     gene            1328..1579
                     /locus_tag="RPH49_002674"
     CDS             1328..1579
                     /locus_tag="RPH49_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125780.1"
                     /translation="MLTLIKLKEDEQVIIYEYIPEDDISNGKGSVTFNKKDAEVIDFS
                     LSEIENEEYFMLYRNKSFSVVRDFIEKQEFPENYKIAWY"
     gene            1655..1827
                     /locus_tag="RPH49_002675"
                     /pseudo
     CDS             1655..1827
                     /locus_tag="RPH49_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002485350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
BASE COUNT          760 a          200 c          293 g          574 t
ORIGIN      
        1 ccggaaaaat taaattctaa agatatctca atatctcaaa tttaatagac tactggagtt
       61 agtagtttga atattgaaag acactaatct aataaaaata cataaaaggt taaactttag
      121 aagtggctgt aaacttcaat gaatactaaa cattgaagtt ttgtaaaagg cgtaaggtat
      181 acaagacaaa tcgtttatct ttgacaaagt aattgatgat gaaaagtcgt taatatgtag
      241 aaacaaaaat tgaaaatata aaatttaact attatgaagt gatgatagcc attaatgaat
      301 agaaaaataa taaaatcatt tatagataaa aaatacgtta agttcacaga atttcgaaaa
      361 aaagcagaaa acattgtaca gatatggaga tgaaaaaatg tcagaataca agaaaaaaat
      421 aattgaatta attgaaagta atttaacagg atatgaaatt tctaaaaaaa ctggagtttc
      481 tcaatacgta ctttcacaat taagacaggg caaacgcgaa gtagataatc taaccctgaa
      541 tacaacagaa aaattatatg aatatgccaa taaagttttg taatttaact aatgtataaa
      601 ttaatcaagc tatgtttatt tgatttaact attaataaaa atcatatggt gaatggatat
      661 tataataatt aaaatacaaa aatagtagat tccaatttgt gaaaaaggag tatgtcgttt
      721 catttagaat ttattgcacg aaattagcat cgaataaggg aaaataagtg ttaagtttta
      781 aatgataaaa aagattggaa tggatcgtct tgaaatgctc ccttcaaagt tttcattttt
      841 tcaatgtcga cttcgaaggg ggcattttca ttaaattgtt atagcttttt atatttgtat
      901 aatgaacata taagtttaag aaggtgcgag tgaaggaaat aaaaaagctc aaatgtacca
      961 aattgttaat cttaataaat ctctacttta taaagattga atggacattc gagcgttaat
     1021 cagtcaggag ggactttccc tcctacaatt taataataat acttgcttca ccactataca
     1081 aggagtgagt tgttatgttc aaagtgaatt attcgatttt aagttattat ccagaatata
     1141 atatcgcagt aagttggcaa cgtttaagag aaggaaaaac aataaaaaac aagatttaat
     1201 actgctgcgt catgaggcgc ttgaacatta tttgatgaat aagtataatt tcaactatga
     1261 ttatgcacat aaaattgtat caaaaaaata cgattattca atttttataa aaaagaaggt
     1321 ggattaaatg cttacattaa taaaattgaa agaagatgaa caggttataa tatatgaata
     1381 tatacctgaa gatgatataa gtaacggtaa aggttcagta acttttaata aaaaagatgc
     1441 agaggttata gatttctcat tatctgaaat agaaaatgaa gaatatttta tgttatatcg
     1501 taataagtct ttttctgtag taagagactt tatcgagaag caagaatttc ccgaaaatta
     1561 taaaatagca tggtattaaa gcatcctttc tacacagata aagagaaagc gatgctattt
     1621 ttatatgctt ttttcattat tcgttgaaaa agaagagtca caaaagttaa catatttaaa
     1681 agaacttggt gaagatggcg aatataaata tgttgccaaa atagatagta aaacatctaa
     1741 attatgtcat tcactcaacg gaaaaatatt taaagttaaa gatatgatac caggtgtgaa
     1801 tgcgccacct atgcatcctt ggtgtag
//
LOCUS       DAPSKH010000136         1802 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPSKH010000136 DAPSKH010000000
VERSION     DAPSKH010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1802
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.140"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            50..844
                     /locus_tag="RPH49_002676"
     CDS             50..844
                     /locus_tag="RPH49_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tandem-type lipoprotein"
                     /protein_id="HDY5125781.1"
                     /translation="MIHSKKLTLGICLVLLIILIVGYVIMTKTNGRNAQIKDTFNQTL
                     KLYPTKNLDDFYDKEGFRDQEFKKGDKGTWIVNSEMVIEPKGKDMETRGMVLYINRNT
                     RTTKGYYFISEMTDDSNGRPKDDEKRYPVKMEHNKIIPTKPLPNDKLRKEIENFKFFV
                     QYGDFKDINDYKDGDISYNPNVPSYSAKYQLKNDDYNVKQLRKRYDIPTNKAPKLLIK
                     GDGDLKGSSVGSKNLEFTFVENKEENIYFTDSVQYTPSEGTSYESN"
     gene            complement(848..970)
                     /locus_tag="RPH49_002677"
     CDS             complement(848..970)
                     /locus_tag="RPH49_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125782.1"
                     /translation="MSYIIKFTFKFFEMATYISQLTLDIELVSSELLVILPGFI"
     gene            1405..1596
                     /locus_tag="RPH49_002678"
     CDS             1405..1596
                     /locus_tag="RPH49_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_501241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125783.1"
                     /translation="MRKEIEALIFSDVSSYDIYVNTGVNQGLIGDIKDGYLTIDSMPY
                     IDAERLYHFAMERKSLVTN"
BASE COUNT          700 a          254 c          310 g          538 t
ORIGIN      
        1 gtaaatatta aaaactgagt caatattaaa aatataaggt ggagaaatga tgattcattc
       61 aaagaaatta acgctcggta tatgcttggt attactcatt atattgattg taggttatgt
      121 cattatgaca aaaacaaatg gtcgaaacgc ccaaattaaa gacacattta atcaaacatt
      181 aaaattatat ccaaccaaaa atctcgatga tttttacgat aaagaaggct ttcgagatca
      241 agaatttaaa aagggtgata aaggtacttg gatagttaat tctgaaatgg taatcgagcc
      301 aaaaggtaag gatatggaaa cgagaggaat ggtgctctat atcaatcgca atactagaac
      361 cacaaaaggg tattatttta taagtgaaat gacagatgac agtaacggca ggccaaagga
      421 tgatgaaaaa aggtatccgg taaaaatgga acataataaa atcataccaa cgaagccact
      481 accgaatgac aagttaagaa aagaaatcga aaactttaaa ttctttgtac aatacggtga
      541 ctttaaagat attaatgatt ataaagatgg tgacatttca tataatccta atgttccaag
      601 ttattccgca aaatatcaat tgaaaaacga tgactacaat gtgaagcaac ttcgaaaaag
      661 atatgatatt ccaaccaaca aagctccgaa attattaata aaaggtgatg gtgatttaaa
      721 aggctcatct gtaggatcaa aaaatctaga atttaccttt gtagaaaata aagaagaaaa
      781 catttatttt acagattctg tacaatatac tccaagtgag ggtacaagtt atgagtcaaa
      841 ctgaatatca aataaaacct ggtaatataa caagtaactc tgaagaaaca agttcgatat
      901 ctaaagtgag ctgtgaaata taggtagcca tttcaaaaaa tttaaaggtg aatttgataa
      961 tgtagctcaa ggagattggg ttaaaaaggc gaagaatgaa ctggatgata ttagtaagaa
     1021 ataaaaaaat attcaaagaa cggaagttta atattctagc cgattcctga aactaagaca
     1081 gcttgtgttc attcatgcca ttatcaatat aatcactaca acaaaaaagc ttctaatgtg
     1141 atacaggaac ctcatattcc gtatcatgtt agaagctttt aatgtctaaa gaacatctac
     1201 attttatcat attttcttac ttattaaact tttatataat taaatatttc ttaattttcc
     1261 aaaatagtga taaatttgtg aaatacatca caaatccctt tatttatttg gaaattcatg
     1321 taatattaga cttgtaagaa gttaataaat agagagagac gagagagttt atataaataa
     1381 tatataaaca ttggagtgat gattatgaga aaagagattg aagcgcttat tttctcagac
     1441 gtaagtagct atgatattta cgtgaacact ggtgtaaatc aaggattaat tggtgacatc
     1501 aaagatggtt acctaactat tgattctatg ccttacattg atgctgagcg tttgtatcac
     1561 tttgctatgg aacgtaaatc gttagtcact aactagttct tattgccaat gattactacc
     1621 cctagtcggc ggcaattgaa gtgtgattga tgtaacttgc cctcgttggt gagcaattga
     1681 gggcagaccc ctttaattaa gtaaacccta actccccaca aatctggaac gatactaaaa
     1741 gccacgtcct atattggatg tggctttagt catgcttata ttatttttaa aacgattacc
     1801 ta
//
LOCUS       DAPSKH010000137         1784 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPSKH010000137 DAPSKH010000000
VERSION     DAPSKH010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.141"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            503..853
                     /gene="scn"
                     /locus_tag="RPH49_002679"
     CDS             503..853
                     /gene="scn"
                     /locus_tag="RPH49_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement inhibitor SCIN-A"
                     /protein_id="HDY5125784.1"
                     /translation="MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNE
                     KLANELKSLLDELNVNELATGSLNTYYKRTIKISGLKAMYALKSKDFKKMSEAKYQLQ
                     KIYNEIDEALKSKY"
     gene            complement(906..1166)
                     /locus_tag="RPH49_002680"
     CDS             complement(906..1166)
                     /locus_tag="RPH49_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125785.1"
                     /translation="MCIVIYLIYSLIVYFICIINFFIMAAPFLMTNADYVWTPMTTVT
                     LFILSLIIFLIFIKTKDVVHLTIFILNLLFSILYCLPILFYL"
     gene            complement(1477..1656)
                     /locus_tag="RPH49_002681"
     CDS             complement(1477..1656)
                     /locus_tag="RPH49_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125786.1"
                     /translation="MKFKTTKECKSNNIFKRSQEINNRESEKGCLWGISMLILLFLLI
                     LFGITACSSSIHFIN"
BASE COUNT          703 a          227 c          235 g          619 t
ORIGIN      
        1 aattgaaatg atctaaaaaa cgctataatt tttctattaa tagtaattaa tatgtgctat
       61 atttatctta gacacagcaa tgtgttcaaa ttttcatcta ttcataagct agccttcggg
      121 ctagtttttt tgtgctatat atttgtttta attaaataaa attagataat gcaatagtag
      181 ccattttatg ttaatattac cttgggcgtt ttcaaggagc gcctttcatt ttttatgtat
      241 tgctcccctt cgggctagta tattaaattt atttttgcgc tttccaaatc aatgtatatg
      301 tgttatattg tttatgggaa gtaggtaagc atttcggtgc ttaccttttt ttgtttttct
      361 ataaatacaa taaggtatgt caatttgata atttattaat tttcatttaa taagaagatc
      421 tatatagtta atgaataatt aatgtacttt ttttagttag tcattaaaat aaattagtac
      481 taattactaa ggagaataaa aaatgaaaat tagaaaatct atacttgcgg gaactttagc
      541 aatcgtttta gcatcaccac tagtaactaa tctagataaa aatgaggcac aagctagcac
      601 aagcttgcca acatcgaatg aatatcaaaa cgaaaagtta gctaatgaat taaaatcgtt
      661 attagatgaa ctaaatgtta atgaattagc tactggaagt ttaaacactt attataagcg
      721 aactataaaa atttcaggtc taaaagcaat gtatgctctt aagtcaaaag actttaagaa
      781 aatgtcagaa gcaaaatatc aacttcaaaa gatttataac gaaattgacg aagcactaaa
      841 aagtaaatat taaaaaaacc acccttttac gggtggtttt aattttctag ataatataaa
      901 agtgttcata aataaaacag tataggcaaa caataaagta ttgaaaaaag taagtttaat
      961 atgaaaattg ttaaatgaac gacatctttt gtttttataa atatcaagaa aataatcaaa
     1021 ctcaaaataa ataacgtaac tgtagtcata ggcgtccata cataatcagc attagtcatt
     1081 aagaatggtg cagccattat gaaaaaattt ataatgcaga tgaaatagac aattagacta
     1141 taaattaggt aaataacaat acacaccctt cataaataaa taatttaaat cctatatatt
     1201 ttaacaaaag taaaacacag aagtgtagaa aataaaaaat attggtaaat aaaatcaata
     1261 agtttaacca atatgttgct cgcttcatac cgtatattgc aacaaaaatt ccgatcaaga
     1321 aaaatatagc ccctatgata aaacagaaat ccgatgctga actattaaaa aatgaggtgt
     1381 ttagagttag aaaatgagtt aatgagttga ctataactaa taagatatta attatatttg
     1441 tatggttctt cacatgatac ctccaagtaa aaaaatctaa ttaataaagt gaatgcttga
     1501 tgaacaagca gttattccaa acagaatcaa taagaaaagt agaatcaaca tgctaatgcc
     1561 ccataaacaa cccttttcac tttctctatt attaatttct tgacttcttt taaagatatt
     1621 attactttta cattctttag ttgttttaaa tttcacgttt ttattacttc cttttgtcta
     1681 aaagtttaca atgaattttt gattataata atatattcaa aatagtacta tctagtttga
     1741 tatgtcaagc aatattatta taaaattgga attctgagtt gtct
//
LOCUS       DAPSKH010000138         1778 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPSKH010000138 DAPSKH010000000
VERSION     DAPSKH010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1778
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.142"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            1..1143
                     /gene="scpA"
                     /locus_tag="RPH49_002682"
     CDS             1..1143
                     /gene="scpA"
                     /locus_tag="RPH49_002682"
                     /EC_number="3.4.22.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019235796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine protease staphopain A"
                     /protein_id="HDY5125787.1"
                     /translation="MALSLIISLSITPIANAESNSNIKAKDKKHVQVNVEDKSVPTDV
                     RNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVLNTEGNIDY
                     IVTISPKVTKDSSSSSKYTINVSSFLSKALNQYKDQQITILTNSKGYYVVTQNHKAKL
                     VLKTPRLEDKKVKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQYVNKLENF
                     KIRETQGNNGWCAGYTMSALLNATYNTNKYHAEAVMRFLHPNLQGQQFQFTGLTPREM
                     IYFGQTQGRNPQLLNRMTTYNEVDNLTKNNKGIAILGSRVESRNGMHAGHAMAVVGNA
                     KLDNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYRWYSSIYGY"
     gene            1174..1500
                     /locus_tag="RPH49_002683"
     CDS             1174..1500
                     /locus_tag="RPH49_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphostatin A"
                     /protein_id="HDY5125788.1"
                     /translation="MEQIELFSIDKFKCNSEAKYYLNIIEGEWHPQDLNDSPLKFILS
                     TSDDSDYICKYINTEHKQLTLYNKNNSSIVIEIFIPNDNKILLTIMNTEALGTSPRMT
                     FIKHKS"
BASE COUNT          696 a          262 c          270 g          550 t
ORIGIN      
        1 atagctttaa gtttaataat ttctttaagt attaccccta ttgcaaacgc cgagagcaat
       61 tcaaatatca aagcaaaaga taagaagcat gtgcaagtta atgtcgagga caagagtgtt
      121 cctactgacg tacgtaattt agcgcaaaaa gactatcttt cttatgttac ttcacttgat
      181 aaaatctata ataaagagaa agcctcgtat acacttggtg aaccttttaa aatttacaaa
      241 ttcaacaaaa agagtgatgg taattattat tttcctgttt tgaacactga aggtaatatc
      301 gattatatag ttacaatttc accaaaagtc actaaggatt ctagttcatc ttctaaatac
      361 acaatcaatg tttcttcatt tttatctaaa gccttaaatc aatataaaga tcaacaaatt
      421 actattttga caaactcaaa aggttactat gtggttactc aaaatcataa agcaaaatta
      481 gtactaaaaa caccacgtct agaagataaa aaggtaaaaa agaccgagag tatacctact
      541 ggcaataatg taacgcaact aaagcaaaaa gcttctgtca ctatgccaac tagtcaattt
      601 aaaagtaata attatactta caacgagcaa tatgtaaata aacttgagaa tttcaagata
      661 agagaaactc aaggtaacaa tggttggtgt gcaggctata cgatgtctgc attactaaat
      721 gcaacttata atactaacaa atatcatgca gaagctgtga tgagattttt acacccaaac
      781 ttacaaggac aacaattcca atttactggt ttaacgccaa gagagatgat ttattttgga
      841 caaactcagg gaagaaatcc acaacttctt aatagaatga ctacatataa tgaagttgac
      901 aatcttacta aaaataataa aggaattgct attttaggta gtagagtaga atcaagaaat
      961 ggtatgcacg cagggcatgc catggcagtt gttgggaatg ctaaattaga caatggacaa
     1021 gaggttataa ttatatggaa tccatgggat aatggtttta tgactcaaga tgctaaaaac
     1081 aatgttattc cagtatccaa tggcgaccat tatcgatggt attcatctat ttatggttat
     1141 taaaatttgt attttagaaa ggtaaataat attatggaac aaattgaatt atttagtatt
     1201 gataaattca aatgtaattc agaggctaag tattatctta atattattga gggagaatgg
     1261 catcctcaag atttaaatga tagtccttta aaatttattc tcagtacctc agacgattct
     1321 gattacattt gcaaatatat aaatacagaa cacaaacaac tcacattata taataaaaat
     1381 aatagctcaa ttgttattga aatatttata ccaaatgata ataaaatact actaacaatt
     1441 atgaacacag aagctttggg aacttctcct agaatgactt tcattaagca taagtcataa
     1501 gactatctag atatgattaa gtaaactatt aatcttatta aaggtctcta ggaagaaaaa
     1561 atttcatgcg atgagattgt tttagaaaaa gcgacgatat atataattta acaatgattt
     1621 taaaatatta agaagaggct gggacataaa tccctaaaaa acagcagtaa gataattttc
     1681 aattagaaaa tatcttactg ctgttctcta cttatacaat acttcgtatt gaatggcttc
     1741 gctttgcccg tctggcacat tactgtaaaa ttctataa
//
LOCUS       DAPSKH010000139         1757 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPSKH010000139 DAPSKH010000000
VERSION     DAPSKH010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1757
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.143"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            33..1019
                     /locus_tag="RPH49_002684"
     CDS             33..1019
                     /locus_tag="RPH49_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer MecR1"
                     /protein_id="HDY5125789.1"
                     /translation="MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVL
                     VSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFET
                     SNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
                     HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQ
                     LYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKS
                     QHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT"
     gene            991..1251
                     /locus_tag="RPH49_002685"
     CDS             991..1251
                     /locus_tag="RPH49_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3387 domain-containing protein"
                     /protein_id="HDY5125790.1"
                     /translation="MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRD
                     SAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQQ"
     gene            complement(1242..>1757)
                     /locus_tag="RPH49_002686"
     CDS             complement(1242..>1757)
                     /locus_tag="RPH49_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125791.1"
                     /translation="CPNNKRLGFKRYAYRHDKYGYKRDFKLYECDDCSECPLKNQCMN
                     FNSKTNKKIMKNYNWEYFKSQINKKLSEPETKNIYSQRKIDVEPVFGFMKAILGFTRM
                     SVRGLNKVKRELGFVLMALNIRKVVAQRAENNQKIYKKDNFYIISIEIVFFHLSKNFM
                     SRTHYDLFFYC"
BASE COUNT          606 a          248 c          285 g          618 t
ORIGIN      
        1 gttataattt ttgtgatatg gaggtgtaga aggtgttatc atctttttta atgttaagta
       61 taatcagttc attgctcacg atatgtgtaa tttttttagt gagaatgctc tatataaaat
      121 atactcaaaa tattatgtca cataagattt ggttattagt gctcgtctcc acgttaattc
      181 cattaatacc attttacaaa atatcgaatt ttacattttc aaaagatatg atgaatcgaa
      241 atgtatctga cacgacttct tcggttagtc atatgttaga tggtcaacaa tcatctgtta
      301 cgaaagactt agcaattaat gttaatcagt ttgagacctc aaatataacg tatatgattc
      361 ttttgatatg ggtatttggt agtttgttgt gcttatttta tatgattaag gcattccgac
      421 aaattgatgt tattaaaagt tcgtcattgg aatcgtcata tcttaatgaa cgacttaaag
      481 tatgtcaaag taagatgcag ttctacaaaa agcatataac aattagttat agttcaaaca
      541 ttgataatcc gatggtattt ggtttagtga aatcccaaat tgtactacca actgtcgtag
      601 tcgaaaccat gaatgacaaa gaaattgaat atattattct acatgaacta tcacatgtga
      661 aaagtcatga cttaatattc aaccagcttt atgttgtttt taaaatgata ttctggttta
      721 atcctgcact atatataagt aaaacaatga tggacaatga ctgtgaaaaa gtatgtgata
      781 gaaacgtttt aaaaattttg aatcgccatg aacatatacg ttatggtgaa tcgatattaa
      841 aatgctctat tttaaaatct cagcacataa ataatgtggc agcacaatat ttactaggtt
      901 ttaattcaaa tattaaagaa cgtgttaagt atattgcact ttatgattca atgcctaaac
      961 ctaatcgaaa caagcgtatt gttgcgtata ttgtatgtag tatatcgagc ttcacatgaa
     1021 acagctaaag aagctttggg cgataaagag ttaagagcca ttgcacatga gttaactaaa
     1081 acagttaagg ataacatgag tgttgattgg tctaaacgag acagtgctaa agctaaaatg
     1141 agagttcaag ttagacgcct attaaagaaa tatggctatc caccagatct tcaaaaaatg
     1201 gctgtggaac aagttgtaga gcaagcagaa ttaatggcaa gtcagcaata aaaaaataaa
     1261 tcataatgag tccgggacat aaagttcttg gataagtgaa aaaagacaat ttctattgaa
     1321 ataatataga aattgtcttt tttataaatt ttttgattat tttcagctcg ttgagctact
     1381 acttttctta tattaagtgc cattaataca aaaccaagtt ctcttttgac tttattgagt
     1441 cctcggacag acatccgagt gaaacccaaa atagccttca taaatccaaa aacaggttcc
     1501 acatcaattt ttctttgact gtagatattt tttgtttctg gttctgaaag ctttttgtta
     1561 atttgggatt taaaatattc ccagttataa ttcttcatta tttttttgtt tgtttttgaa
     1621 ttgaagttca tacattgatt tttcagagga cattctgaac aatcatcaca ttcatataat
     1681 ttgaagtctc gcttataacc atacttatca tgacgatagg catatctttt aaaacctagc
     1741 cgtttattat tcggaca
//
LOCUS       DAPSKH010000140         1669 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPSKH010000140 DAPSKH010000000
VERSION     DAPSKH010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1669
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.145"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(75..803)
                     /gene="sei"
                     /locus_tag="RPH49_002687"
     CDS             complement(75..803)
                     /gene="sei"
                     /locus_tag="RPH49_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type I"
                     /protein_id="HDY5125792.1"
                     /translation="MKKFKYSFILVFILLFNIKDHTYAQGDIGVGNLRNFYTKHDYID
                     LKGVTDKNLPIANQLEFSTGTNDLISESNNWDEISKFKGKKLDIFGIDYNGPCKSKYM
                     YGGATLSGQYLNSARKIPINLWVNGKHKTISTDKIATNKKLVTAQEIDVKLRRYLQEE
                     YNIYGHNNTGKGKEYGYKSKFYSGFNNGKVLFHLNNEKSFSYDLFYTGDGLPVSFLKI
                     YEDNKIIESEKFHLDVEISYVDSN"
     gene            complement(838..1557)
                     /gene="sem"
                     /locus_tag="RPH49_002688"
     CDS             complement(838..1557)
                     /gene="sem"
                     /locus_tag="RPH49_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_058008129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type M"
                     /protein_id="HDY5125793.1"
                     /translation="MKRILIIVVLLFCYSQNHIATADVGVLNLRNYYGSYPIEDHQSI
                     NPENNHLSHQLVFSMDNSTVTAEFKNVDDVKKFKNHAVDVYGLSYSGYCLKNKYIYGG
                     VTLAGDYLEKSRRIPINLWVNGEHQTISTDKVSTNKKLVTAQEIDTKLRRYLQEEYNI
                     YGFNDTNKGRKYGNKSKFSSGFNAGKILFHLNDGSSFSYDLFDTGTGQAESFLKIYND
                     NKTVETEKFHLDVEISYKDES"
BASE COUNT          553 a          261 c          180 g          675 t
ORIGIN      
        1 ctttaaaatt taaatagtta atacatatat taatttcgta taaattcgca ttttagtgtt
       61 aaaactaatt atcattagtt actatctaca tatgatattt cgacatcaag atgaaatttt
      121 tcagattcta ttattttatt atcttcataa attttcaaaa aacttacagg cagtccatct
      181 cctgtataaa acaaatcata tgaaaatgat ttttcattat ttaaatgaaa taaaactttc
      241 ccattattaa aacctgaata aaatttagat ttatatccat attctttgcc tttaccagtg
      301 ttattatgac catagatatt gtattcttct tgaagatatc ttcttaattt aacatcaatt
      361 tcttgagctg ttactagttt tttattagtt gctattttgt cagtagaaat tgttttatgt
      421 ttgccattaa cccaaagatt aatagggatt tttctagcag aatttaagta ttgtcctgat
      481 aaagtggccc ctccatacat gtatttagat ttacaaggac cattataatc aatgccaaaa
      541 atatccagtt tctttccttt aaatttactt atttcgtccc aattattaga ttctgagatc
      601 aaatcattgg tacctgttga aaattcgagt tgatttgcaa taggtaggtt tttatctgtg
      661 acgcctttta aatctatata atcatgtttt gtatagaaat ttcttaagtt acctacacca
      721 atatcacctt gagcatacgt atgatcttta atgttaaaaa gtaatataaa aactaatata
      781 aaactatatt taaatttttt catggcattt cctttactaa gttatgattg aaatacttca
      841 actttcgtcc ttataagata tttctacatc taaatggaat ttttcagttt cgacagtttt
      901 gttgtcatta tatattttta agaaactttc agcttgtcct gttccagtat caaataagtc
      961 ataagaaaat gatgaaccat cattcaaatg aaataatatt tttcctgcat taaatccaga
     1021 actaaatttt gacttattac catattttct tcctttattt gtatcattaa agccataaat
     1081 attatattct tcttgtagat atcttcttaa tttagtatca atttcttgag ctgttactaa
     1141 ctttttatta gttgatactt tgtcagtaga tatagtttga tgttctccat taacccaaag
     1201 attaatagga atacgtctag atttctctaa ataatcacct gctaatgtaa ctccaccgta
     1261 tatatatttg tttttcaaac aatatccact ataacttaga ccatatacat ctacagcatg
     1321 atttttgaat ttctttacat catcaacgtt cttaaattca gctgttactg tcgaattatc
     1381 catagaaaaa actaattgat gcgaaagatg attattttca ggattaatac tttggtggtc
     1441 ttcaattgga tagctaccat aatagttcct aagattcaaa actccgacat cagcggttgc
     1501 gatatgattt tgcgaatagc aaaacaataa aacaacaatg ataagtattc ttttcatatt
     1561 ttatttctcc tatatttaaa cttctctatc tttattatct tttattgtaa aaataaccaa
     1621 ttcttcttaa atcatcatga ttctatccca cttatatatt attactcgt
//
LOCUS       DAPSKH010000141         1609 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPSKH010000141 DAPSKH010000000
VERSION     DAPSKH010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1609
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.146"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..563)
                     /locus_tag="RPH49_002689"
     CDS             complement(<1..563)
                     /locus_tag="RPH49_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDY5125794.1"
                     /translation="MLCEVIAIYKNPKYRIIKYNDEYLMVNIINNWLVLFIPLLNWLT
                     PKRYIKISQEELESLNTFKPAKNNAFWPALGSSVLFSVTFRKYMPLFNVRLEKTIVIA
                     IFFVVFLGILFFYLNLNRRLALSVFTMNKEKSQKMILLPNLKHFFFIIFAYLYFGGFS
                     FFTLYALITIDVQNIIIFICWGAVTMF"
     gene            complement(703..1323)
                     /locus_tag="RPH49_002690"
     CDS             complement(703..1323)
                     /locus_tag="RPH49_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000882081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 domain-containing protein"
                     /protein_id="HDY5125795.1"
                     /translation="MLCESKIINKNPKYRIIKYNDEYLMIDIISTWISLFFPFINWFI
                     TKRYVKISREEFENLNIVKPAKKNVFWPVAGSSALLGVALRKYTHLLDVQLDKKLVIA
                     ICCITFIGILIFYVRLIKKSSLNIYNTKNKRSKIFLIPTLKNVCFTLFGYILFGGLTM
                     LFLDALLSMSYQNIIVYFAWITAIMGFFLVNIALIIDKNIHVILKN"
     gene            complement(1370..>1609)
                     /locus_tag="RPH49_002691"
     CDS             complement(1370..>1609)
                     /locus_tag="RPH49_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HDY5125796.1"
                     /translation="KNNELKLRLLPSFKNMCFTIFYYLFTGFMSYGAFYLLVFENVQN
                     LILYISWLFMTMLFMLMNMHSIIDKKVHIFLKSNK"
BASE COUNT          629 a          228 c          174 g          578 t
ORIGIN      
        1 aaaaacatag ttactgcacc ccaacagata aatataatta tattttgaac atctatagtt
       61 atcagggcat ataaagtgaa aaatgaaaaa ccaccgaaat ataaatatgc aaatattata
      121 aagaaaaaat gttttaaatt aggtagcaat atcattttct gacttttttc tttattcata
      181 gtaaaaacac ttaatgctag cctacgattt aaatttaggt agaaaaataa aataccaaga
      241 aatacaacaa aaaatatggc tattactatt gttttttcca atctaacatt aaataaaggc
      301 atatactttc taaaagtcac actaaataaa actgaactac ctaatgctgg ccaaaatgca
      361 ttgtttttag caggtttgaa agtatttaaa ctttctaatt cttcttgact gatcttgatg
      421 tatctttttg gtgtcaacca attaagcaat ggaatgaata aaactaacca attatttatt
      481 atattcacca tcaaatattc atcattatat ttaataattc tatatttggg atttttgtat
      541 atagctatta cctcgcaaag caatgtctcc acatcccttt aattttatgt gtaatacatt
      601 tttcgatact tcaaaagaca ttaaaatatt atcaacttac tatcattaaa aattttattc
      661 attgttattt gcatatcttt aatctgaatt tattactacc acttaatttt taagtatgac
      721 atgaatgttt ttatctataa ttaaagctat attcactaga aaaaaaccca ttattgctgt
      781 aatccaagca aaatatacta ttatgttttg ataactcatt gataatagag catctaggaa
      841 tagcatagtc aatccgccaa ataaaatata tccaaataat gtgaaacaaa cattttttag
      901 tgtaggtatt aaaaaaattt ttgacctttt atttttagta ttataaatat ttaaagatga
      961 ttttttaatt aggcgtacat aaaatattaa aatccctata aatgtgatgc aacatatggc
     1021 aataactaat tttttatcaa gttgaacgtc aagtaaatgt gtatattttc ttaatgcaac
     1081 tcccagcaaa gcagagctac ctgcaactgg ccaaaaaaca ttctttttag caggtttaac
     1141 aatatttaaa ttttcaaact cttctctact aattttgacg tatcttttgg tgatgaacca
     1201 attaataaaa ggaaaaaaca aactaatcca agtgcttatt atatcgatca ttaagtactc
     1261 atcattatat ttaataattc tatatttagg atttttattg atgattttag attcgcacag
     1321 caatgtttac accccctaat tagcaattga aaaccaacta aatttgtaac tatttattag
     1381 actttaaaaa tatatgtact tttttatcta taattgaatg catattcatt aacataaata
     1441 gcatagtcat gaaaagccaa gaaatatata agattaaatt ttgtacattt tcaaacacca
     1501 acaagtaaaa tgccccataa gacatgaaac cagtaaagag gtaataaaaa attgtgaaac
     1561 acatattttt aaaggagggt aataatctta atttaagttc attattttt
//
LOCUS       DAPSKH010000142         1558 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPSKH010000142 DAPSKH010000000
VERSION     DAPSKH010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1558
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.148"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            59..1264
                     /locus_tag="RPH49_002692"
     CDS             59..1264
                     /locus_tag="RPH49_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDY5125797.1"
                     /translation="MWIEKFKNKNNETKYRYYEKYKDPYTDKWKRVSVVLNKNTKQSQ
                     KEAMFRLEEKIKEKLNNKSSSELKTLTFHALLDEWLEYHIKTSGSKLTTLNNIKIRIK
                     NIKRYCSENLLLNKLDTKYMQIFINKLSDIYSQNQVTRQLGDMKGAIKYAVKFYNYPN
                     EYLLTNVKIPKRRKTIEDIEKDESKMYNYLEMNQVLQIRDHILNDNKLHKRNRILIAS
                     ILEVQALTGMRIGELQALQEKDIDLLNKTINITGTIHRIKYEEGFGYKDTTKTISSKR
                     SISINSRTVEIFKKIILENKMLKRWNSSYVDRGFIFTTKKGNPLCNNQIAGVLKKTTK
                     ALNMNKKVTTHTFRHTHITLLVEMNVSLKAIMKRVGHVDEKTTIRIYTHVTEKMDREL
                     TQKLENIPS"
     gene            complement(1307..1516)
                     /locus_tag="RPH49_002693"
     CDS             complement(1307..1516)
                     /locus_tag="RPH49_002693"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125798.1"
                     /translation="MLEVLKNKLKNLDEFLNNLKIASPILENHLDDIVRNMKPLIVNQ
                     IFEPSHYDDMFISRKALTPVFSSVL"
BASE COUNT          653 a          230 c          220 g          455 t
ORIGIN      
        1 ctacccttat tattttttaa tattttatag aacatacgtt cttgcaggag gtataaacat
       61 gtggattgaa aaatttaaaa acaaaaataa cgaaactaaa tacagatact acgagaagta
      121 taaagatcca tacacagata aatggaagcg cgtaagtgtt gtgttgaaca agaatacaaa
      181 acaatcacaa aaagaagcaa tgtttcgttt agaagaaaaa ataaaagaaa aactaaacaa
      241 caagtcgtca agcgaattaa aaactttgac ttttcacgcg ctattagatg aatggcttga
      301 atatcatata aaaacatcag gttcaaagtt gactactctt aataatataa aaataagaat
      361 taaaaacatt aaacgatact gctctgagaa cttgctttta aacaaacttg atacaaaata
      421 tatgcagata tttattaata aattatcaga tatctattct caaaatcaag taacccgtca
      481 actcggagat atgaaaggag ctattaaata tgcagttaaa ttttacaatt atccaaatga
      541 atatttgtta actaatgtca aaattcctaa aagaagaaaa acaatagagg atatcgaaaa
      601 agatgaatct aaaatgtaca actatttaga aatgaaccaa gtcctacaga tacgtgatca
      661 tatactaaat gataataagt tacacaagcg aaatcgcatt ttaattgcca gcatcttaga
      721 agtacaggct ttaactggta tgcgcatagg agaactacaa gcactgcagg aaaaagatat
      781 agatttatta aacaaaacta tcaatataac aggtacaatt caccgcatta aatacgagga
      841 aggattcgga tacaaagaca ctacaaagac tataagttca aaaagaagta tcagcatcaa
      901 ttctagaacc gtagaaattt ttaaaaagat aatactggaa aacaaaatgt tgaaaagatg
      961 gaattcgagc tatgttgaca gagggttcat attcacaaca aaaaaaggga atcctttatg
     1021 taataatcaa atcgcaggtg tgcttaagaa aactacaaaa gctttaaata tgaataagaa
     1081 agttaccacg cacacattta gacatacaca cataacttta ttagtagaaa tgaatgtttc
     1141 tttaaaagca attatgaaaa gggtaggaca tgtagatgaa aaaacaacca ttcgcatata
     1201 tactcatgta actgaaaaaa tggatagaga actaactcaa aaactcgaaa acattccaag
     1261 ttagcttaaa tctgcccttt ttttgccctt atatttttta caagctttat aaaacgcttg
     1321 agaacactgg cgttaaagct tttcttgaaa taaacatatc atcataatgt gatggttcaa
     1381 aaatctgatt aacaattaac ggtttcatat ttctaactat atcatctaag tgattttcta
     1441 aaatcggcga agctattttt aaattattta aaaattcgtc taagttttta agtttatttt
     1501 ttaaaacttc aagcatttta tcaatttcgt caacatttat tcccattgcc tttatctt
//
LOCUS       DAPSKH010000143         1534 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPSKH010000143 DAPSKH010000000
VERSION     DAPSKH010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1534
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.149"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            266..1225
                     /gene="hyl"
                     /locus_tag="RPH49_002694"
     CDS             266..1225
                     /gene="hyl"
                     /locus_tag="RPH49_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hemolysin"
                     /protein_id="HDY5125799.1"
                     /translation="MKTRIVSSVTTTLLLGSILMNPVANAADSDINIKTGTTDIGSNT
                     IVKTGDLVTYDKENGMHKKVFYSFIDDKNHNKKILVIRTKGTIAGQYRVYSEEGANKS
                     GLAWPSAFKVQLQLPDNEVAQISDYYPRNSIDTKEYMSTLTYGFNGNVTGDDSGKIGG
                     LIGANVSIGHTLKYVQPDFKTILESPTDKKVGWKVIFNNMVNQNWGPYDRDSWNPVYG
                     NQLFMKTRNGSMKAADNFLDPNKASSLLSSGFSPDFATVITMDRKATKQQSNIDVIYE
                     RVRDDYQLHWTSTNWKGTNTKDKWTDRSSERYKIDWEKEEMTN"
BASE COUNT          586 a          227 c          234 g          487 t
ORIGIN      
        1 ttgtcttttc cttggttcat aaagagttca ttcaactttg actaagcctc gaaattgaaa
       61 tgcttccttt caaatattaa ttaaaagtta aaaacatatt cttaaaatat tcactcatca
      121 tcactcaatc atttaacagt tgctacatta aatatactaa tataaacgat gataaatatt
      181 tgatatgtct caactgcatt attctaaatt gacatattga ttattgtttc ctcaaatcgt
      241 tttaaaaaat agaaggatga tgaaaatgaa aacacgtata gtcagctcag taacaacaac
      301 actattgcta ggttccatat taatgaatcc tgtcgctaat gccgcagatt ctgatattaa
      361 tattaaaacc ggtactacag atataggaag caatactata gtaaaaacag gtgatttagt
      421 cacttatgat aaagaaaatg gcatgcacaa aaaagtattt tatagtttta tcgatgataa
      481 aaatcacaat aaaaaaatat tagtcatcag aacgaaaggt accattgctg gtcagtatag
      541 agtttatagc gaagaaggcg ctaataaaag tggtttagcc tggccttcag cctttaaggt
      601 acagttgcaa ctacctgata atgaagtagc acaaatttct gattactatc ctagaaattc
      661 aattgatact aaagaatata tgagtacatt aacttatgga ttcaacggta atgtgactgg
      721 tgatgattct ggaaaaattg gcggtttgat tggtgcaaat gtttcaattg gtcatacact
      781 caaatatgtt caaccagatt tcaaaacaat tttagaaagt ccaactgata aaaaagtagg
      841 ttggaaagtt atatttaaca atatggtgaa tcaaaattgg ggaccatacg acagagattc
      901 ttggaaccca gtatacggca atcaactttt catgaaaaca agaaacggtt caatgaaagc
      961 agcagataac ttccttgatc ctaacaaagc aagttctcta ttatcttcag ggttttcacc
     1021 agacttcgct acagttatta ctatggatag gaaagcaacc aaacaacaat caaatataga
     1081 tgtaatatac gaacgagttc gtgatgacta tcaattacat tggacttcaa caaattggaa
     1141 aggtactaat actaaagata aatggacgga tcgttcttca gaaagatata aaatcgattg
     1201 ggaaaaagaa gaaatgacaa attaatggtc atgcacactc aaatattcaa attttaacat
     1261 tagccgataa catcagaaat gatgtgtgtc ggctatttta gttgcagtat aaaattaaac
     1321 atcgatgaat agtaatatat atattatgct tttcaatata tattcatgct tataaacacg
     1381 atataagatt taatttttca gtttcaaaca tttttaattc atattgtcaa accctttatt
     1441 taaaagtttt gaaattgttc aaaacttatc gaacacatta tgtgttaata tatttgcaga
     1501 attattttaa aatcgtttta aaactatact gaaa
//
LOCUS       DAPSKH010000144         1525 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPSKH010000144 DAPSKH010000000
VERSION     DAPSKH010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1525
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.151"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            8..1447
                     /locus_tag="RPH49_002695"
                     /note="aph(2'')-Ia"
     CDS             8..1447
                     /locus_tag="RPH49_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDY5125800.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          656 a          108 c          258 g          503 t
ORIGIN      
        1 taaataaatg aatatagttg aaaatgaaat atgtataaga actttaatag atgatgattt
       61 tcctttgatg ttaaaatggt taactgatga aagagtatta gaattttatg gtggtagaga
      121 taaaaaatat acattagaat cattaaaaaa acattataca gagccttggg aagatgaagt
      181 ttttagagta attattgaat ataacaatgt tcctattgga tatggacaaa tatataaaat
      241 gtatgatgag ttatatactg attatcatta tccaaaaact gatgagatag tctatggtat
      301 ggatcaattt ataggagagc caaattattg gagtaaagga attggtacaa gatatattaa
      361 attgattttt gaatttttga aaaaagaaag aaatgctaat gcagttattt tagaccctca
      421 taaaaataat ccaagagcaa taagggcata ccaaaaatct ggttttagaa ttattgaaga
      481 tttgccagaa catgaattac acgagggcaa aaaagaagat tgttatttaa tggaatatag
      541 atatgatgat aatgccacaa atgttaaggc aatgaaatat ttaattgagc attactttga
      601 taatttcaaa gtagatagta ttgaaataat cggtagtggt tatgatagtg tggcatattt
      661 agttaataat gaatacattt ttaaaacaaa atttagtact aataagaaaa aaggttatgc
      721 aaaagaaaaa gcaatatata attttttaaa tacaaattta gaaactaatg taaaaattcc
      781 taatattgaa tattcgtata ttagtgatga attatctata ctaggttata aagaaattaa
      841 aggaactttt ttaacaccag aaatttattc tactatgtca gaagaagaac aaaatttgtt
      901 aaaacgagat attgccagtt ttttaagaca aatgcacggt ttagattata cagatattag
      961 tgaatgtact attgataata aacaaaatgt attagaagag tatatattgt tgcgtgaaac
     1021 tatttataat gatttaactg atatagaaaa agattatata gaaagtttta tggaaagact
     1081 aaatgcaaca acagtttttg agggtaaaaa gtgtttatgc cataatgatt ttagttgtaa
     1141 tcatctattg ttagatggca ataatagatt aactggaata attgattttg gagattctgg
     1201 aattatagat gaatattgtg attttatata cttacttgaa gatagtgaag aagaaatagg
     1261 aacaaatttt ggagaagata tattaagaat gtatggaaat atagatattg agaaagcaaa
     1321 agaatatcaa gatatagttg aagaatatta tcctattgaa actattgttt atggaattaa
     1381 aaatattaaa caggaattta tcgaaaatgg tagaaaagaa atttataaaa ggacttataa
     1441 agattgatta tataatatat gaaaagctat tataaaagac attagtatta aatagtttaa
     1501 aaaaatgaaa aataataaag gaagt
//
LOCUS       DAPSKH010000145         1494 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPSKH010000145 DAPSKH010000000
VERSION     DAPSKH010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1494
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.152"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(190..417)
                     /locus_tag="RPH49_002696"
     CDS             complement(190..417)
                     /locus_tag="RPH49_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125801.1"
                     /translation="MKNYYHLLSFDDDLANDAANDLLKEGWDIVHVGTKLVKILDNGQ
                     AYYNTEYVLGGTKNQYEKYLEDCQQSELDYF"
     gene            473..799
                     /locus_tag="RPH49_002697"
     CDS             473..799
                     /locus_tag="RPH49_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125802.1"
                     /translation="MNIQKVMKLILKKIHEMREILKKFNKNIRHKDLIVIKVKDENSV
                     PLVIYKGGELKSKRVVKFLWVTRNGNYEGGYDINIEHYAKSEKGRPGRYEKSGFRSLF
                     FKEDSQ"
     gene            796..1014
                     /locus_tag="RPH49_002698"
     CDS             796..1014
                     /locus_tag="RPH49_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125803.1"
                     /translation="MNKLCKTTLLITMAVVTWKVWKIEKHTRKPVISSRALSDYLNNK
                     SLTIPKDAENSTESARRLLKFAEQTISK"
     gene            1044..1307
                     /locus_tag="RPH49_002699"
     CDS             1044..1307
                     /locus_tag="RPH49_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5125804.1"
                     /translation="MPKIIVPPTPENTYRGEEKFVKKLYATPTQIHQLFGVCRSTVYN
                     WLKYYRKDNLGVENLYIDYSPTGTLINISKLEEYLIRKHKKWY"
     gene            1319..1456
                     /locus_tag="RPH49_002700"
     CDS             1319..1456
                     /locus_tag="RPH49_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1270 family protein"
                     /protein_id="HDY5125805.1"
                     /translation="MSDTYKSYLLAVLCFTVLAIVLMPFLYFTTAWSIAGFASIVEMI
                     I"
BASE COUNT          588 a          227 c          257 g          422 t
ORIGIN      
        1 aagatatgaa agaactttat tctttaaaaa tccaaaagaa gaatttaaat aataaacaaa
       61 agaatttaat gtctgtaatt aatcaatgta ttgaactaga aaagttttct tacactgaaa
      121 ttaaaaaagt tctctaccta attgatagag aacaaaagta tttagctaat aaccgcagaa
      181 aaacataagt taaaaataat ctaactcgga ctgctggcaa tcttctaaat atttttcata
      241 ctgattttta gttccgccca gaacgtattc agtattgtag tacgcttgtc cattatccaa
      301 aattttaact aattttgtac caacatgaac gatatcccaa ccttctttta acagatcgtt
      361 ggctgcatca ttagctaaat cgtcatcgaa agacaaaagg tgatagtagt ttttcataat
      421 atacacctcc ttaggtggat aactaaatta tacacgaaaa gagatgtaac aaatgaacat
      481 tcaaaaagta atgaaattaa tattgaaaaa aattcatgag atgagggaga ttttaaaaaa
      541 gttcaacaaa aatatcagac acaaagatct aattgtcatc aaagtgaaag atgaaaacag
      601 cgttccatta gtcatttata aaggtggaga gctgaagagc aaacgagtag ttaaattttt
      661 atgggtaact agaaacggaa attacgaagg tggttacgac ataaacatag agcattatgc
      721 aaagagtgaa aaaggcagac ccggtagata tgaaaaatca ggatttagaa gtttgttttt
      781 taaggaggat tcacagtgaa caaattgtgt aaaacaaccc tcctcatcac aatggcagtt
      841 gtgacgtgga aggtttggaa gattgagaag cacactagaa aacctgtgat tagtagcagg
      901 gcgttgagtg actatctaaa caacaaatct ttaaccatac cgaaagatgc tgaaaattct
      961 actgaatctg ctcgtcgcct tttgaagttc gccgaacaaa ctattagcaa ataacaacat
     1021 tatacacgaa aggaaagata gaaatgccaa aaatcatagt accaccaaca ccagaaaaca
     1081 catatagagg cgaagaaaaa tttgtgaaaa agttatacgc aacacctaca caaatccatc
     1141 aattgtttgg agtatgtaga agtacagtat acaactggtt gaaatattac cgcaaagata
     1201 atttaggtgt agaaaattta tacattgatt attcaccaac aggcactctg attaatattt
     1261 ctaaattgga agagtatttg atcagaaagc ataaaaaatg gtattaggag gatattaaat
     1321 gagcgacaca tataaaagct acctattagc agtactatgc ttcacagtct tagcgattgt
     1381 actcatgccg tttctatact tcactacagc gtggtcaatt gcgggattcg caagtattgt
     1441 ggaaatgata atttaataat gtacactttt gattgtttaa acatgtacaa tttt
//
LOCUS       DAPSKH010000146         1456 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPSKH010000146 DAPSKH010000000
VERSION     DAPSKH010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.153"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..403
                     /locus_tag="RPH49_002701"
     CDS             <1..403
                     /locus_tag="RPH49_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000277741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125806.1"
                     /translation="DFKLYERDDCSACSLRHQCMKPNLKSNKKIMKNYNWEYFKAQIN
                     QKLSKPETKKIYSQRKIDVEPVFGFMKAILGFTRMSVRGINKVKRELGFVLMALNIRK
                     IAAQRAVHYKIHIKKADFYQIINRNQLFYIA"
     gene            complement(429..1418)
                     /gene="trpS"
                     /locus_tag="RPH49_002702"
     CDS             complement(429..1418)
                     /gene="trpS"
                     /locus_tag="RPH49_002702"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDY5125807.1"
                     /translation="METLFSGIQPSGIPTIGNYIGALKQFVDVQNDYDCYFCIVDQHA
                     ITMPQDRLKLRKQTRQLAAIYLASGIDPDKATLFIQSEVPAHVQAGWMLTTIASVGEL
                     ERMTQYKDKAQKAVEGIPAGLLTYPPLMAADIVLYNTNIVPVGDDQKQHIELTRNLVD
                     RFNSRYNDVLVKPEIRMPKVGGRVMSLQDPTRKMSKSDDNTKNFISLLDEPNVAAKKI
                     KSAVTDSDGIIKFDRDNKPGITNLISIYAGLTDMPIKDIEAKYEGEGYGKFKGDLAEI
                     VKAFLVEFQEKYESFYNSDKLDDILDQGRDKAHKVSFKTVKKMEKAMGLGRKR"
BASE COUNT          463 a          254 c          227 g          512 t
ORIGIN      
        1 tgacttcaag ctatatgaac gcgatgactg ttcagcatgt tctttgagac atcaatgcat
       61 gaagccaaat ttgaaatcca ataagaaaat catgaagaat tataattggg aatactttaa
      121 agcccaaatt aatcaaaagc tttctaaacc agaaacgaaa aaaatctata gtcaaagaaa
      181 aattgatgta gagcctgttt ttggatttat gaaggctatt ttgggtttca ctcgaatgtc
      241 agttcgagga ataaataaag ttaaacgaga gctaggtttt gtattaatgg cacttaatat
      301 aaggaaaata gcagctcaac gagctgtaca ttataaaata catatcaaaa aagctgattt
      361 ctatcaaata attaatagaa atcagctttt ttacattgcc taagaactta atgtcccaag
      421 ctcttatttt atctcttacg tcctaaaccc atcgcttttt ccattttttt gacagtttta
      481 aatgaaactt tgtgtgcttt atctctacct tgatctaaaa tatcatcaag tttatctgag
      541 ttatagaaac tttcgtattt ttcttggaat tctactaaaa atgctttaac tatttcagca
      601 aggtcgcctt taaatttacc gtaaccttca ccttcatatt ttgcctcaat atctttaata
      661 ggcatgtctg ttaatccagc gtatattgaa attaaatttg taatacctgg tttattgtcg
      721 cggtcgaatt taataatacc gtctgaatca gtcacagcac ttttaatttt tttagcagca
      781 acatttggtt cgtctaataa tgaaatgaag tttttagtat tatcatcact cttactcatt
      841 tttcttgttg ggtcttgtaa actcatgaca cgtccaccaa ctttaggcat acgaatttca
      901 ggtttcacaa gcacatcatt atagcgacta ttaaatctat ctacaaggtt acgagtcaat
      961 tcgatatgct gcttttggtc atcgccaact ggaacgatat tagtattgta aagaacaata
     1021 tcagctgcca ttaaaggtgg atatgttaat agaccagctg gtataccttc aactgctttc
     1081 tgagctttat ctttgtattg cgtcatacgc tctaattctc caacagaagc aatcgtagtt
     1141 aacatccatc ctgcttgtac gtgtgcaggg acttcagatt gtatgaacaa tgttgctttg
     1201 tctggatcta taccagaagc taaataaatc gctgctaatt gtctagtttg tttacgtaat
     1261 tttaagcgat cttgtggcat tgtaattgca tgttgatcta cgatacagaa ataacaatca
     1321 tagtcatttt gcacatcaac aaattgtttt agtgcgccaa tataatttcc aatagtagga
     1381 attccactag gttggatgcc tgaaaataat gtctccattt aaatgcctac tttcttagta
     1441 atattttaat aattat
//
LOCUS       DAPSKH010000147         1404 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPSKH010000147 DAPSKH010000000
VERSION     DAPSKH010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.154"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..762
                     /locus_tag="RPH49_002703"
     CDS             <1..762
                     /locus_tag="RPH49_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125808.1"
                     /translation="SKHSSDSDGESNSHISIGYGTVNHPFNSSAIGHKKKLDQDDEID
                     PLHMRHFGDRIGNVIKNALGVVGISGLLASFWFFIAKRRRKEDEEEELEIRDNSKDKK
                     KGSIEGTKHLPLLLAKRRRKEDEEDAIVEEKDSLNNNESLDKVKHTPFFLPKRRRKED
                     EEDVEVTNENTDEKVLQDNEHSPLLIAKRRKDKEVDVETTPSIESNEDDAPLLLAKKK
                     NQKDNQSKGKKSASKKPSKKLVAKKKKKKSKKNKK"
     gene            complement(821..1222)
                     /locus_tag="RPH49_002704"
     CDS             complement(821..1222)
                     /locus_tag="RPH49_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDY5125809.1"
                     /translation="MAKINFDAATKGNPGISTCAVVIKEDDQHYTYTHELGEMDNHTA
                     EWAACIYALKHARELNVSNALLYTDSKLIADSVNAGYVKNAKFKPYFDQLEIFEQDFD
                     LLFVKWIPREQNKEANQNAQQALYKLIKKNK"
BASE COUNT          519 a          236 c          234 g          415 t
ORIGIN      
        1 agcaagcatt catcagattc ggacggtgaa tctaatagtc atataagcat tggatatgga
       61 actgtaaacc atccattcaa tagttcggct attggacata aaaagaaatt ggatcaagat
      121 gatgaaatcg atccacttca tatgcgtcat ttcggtgacc gaattggtaa tgttatcaaa
      181 aacgcacttg gcgttgttgg tatttccgga ttacttgcta gcttctggtt cttcattgcg
      241 aaacgtcgtc gtaaagagga tgaagaggaa gaattggaaa ttagagataa tagcaaagac
      301 aagaagaaag gttcaataga aggtactaaa catttaccac ttttattagc gaaacgtcgc
      361 agaaaagaag atgaagaaga tgctattgtt gaagaaaaag attcgctaaa caataacgag
      421 tcactcgata aagttaaaca tacgccgttc ttcttaccta aacgtcgtcg caaagaagat
      481 gaagaagatg tggaagttac aaatgaaaac acagatgaaa aagtgttgca agataacgaa
      541 cattcaccac tcttaatcgc aaaacgacgc aaagataaag aggtagatgt tgaaacaaca
      601 cctagtattg aatctaatga agatgacgca cctttattat tggctaaaaa gaaaaatcaa
      661 aaagataacc aatccaaagg gaaaaagtcg gcatcaaaaa aaccttctaa aaagctagta
      721 gctaaaaaga agaaaaagaa atctaaaaaa aataaaaaat aatttgtttc ttcgataaaa
      781 agaggagcac cgattgaaat tatgtcagtc ggtgctcctt ttatttgttc tttttaatta
      841 atttgtacaa tgcttgctgt gcgttttgat tcgcttcttt gttttgttct ctcggaatcc
      901 atttaacaaa taataaatca aaatcttgtt caaatatttc caattgatca aaataaggtt
      961 taaattttgc attttttaca taaccagcgt taacactatc cgcaattaac ttagagtcag
     1021 tgtacaacaa cgcattgcta acgtttaatt cacgggcgtg tttcaatgca tagatacaag
     1081 cagcccattc tgcagtgtga ttatccattt cgcctaactc atgtgtatat gtataatgct
     1141 gatcatcttc tttgattaca acggcacacg tacttatgcc tggatttcct ttcgtcgcag
     1201 catcaaaatt tattttcgcc ataataaacc tactttctat tcaatactta gttaaagtta
     1261 ctattactgt aatacaaaat atattaaaca atctattaaa aaacacgcat cacttaaata
     1321 agtaacacgt gtttaaaata cttgctgatt caaagatgat tttctaatac gtagtactgt
     1381 aatatacttc ctaaaaaaat catc
//
LOCUS       DAPSKH010000148         1346 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPSKH010000148 DAPSKH010000000
VERSION     DAPSKH010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1346
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.155"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            71..185
                     /gene="rrf"
                     /locus_tag="RPH49_002705"
     rRNA            71..185
                     /gene="rrf"
                     /locus_tag="RPH49_002705"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            197..272
                     /locus_tag="RPH49_002706"
     tRNA            197..272
                     /locus_tag="RPH49_002706"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:230..232,aa:Val,seq:tac)
     gene            289..364
                     /locus_tag="RPH49_002707"
     tRNA            289..364
                     /locus_tag="RPH49_002707"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:322..324,aa:Thr,seq:tgt)
     gene            370..445
                     /locus_tag="RPH49_002708"
     tRNA            370..445
                     /locus_tag="RPH49_002708"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:403..405,aa:Lys,seq:ttt)
     gene            449..530
                     /locus_tag="RPH49_002709"
     tRNA            449..530
                     /locus_tag="RPH49_002709"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:483..485,aa:Leu,seq:tag)
     gene            534..608
                     /locus_tag="RPH49_002710"
     tRNA            534..608
                     /locus_tag="RPH49_002710"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:566..568,aa:Gly,seq:gcc)
     gene            619..707
                     /locus_tag="RPH49_002711"
     tRNA            619..707
                     /locus_tag="RPH49_002711"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:653..655,aa:Leu,seq:taa)
     gene            726..799
                     /locus_tag="RPH49_002712"
     tRNA            726..799
                     /locus_tag="RPH49_002712"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:760..762,aa:Arg,seq:acg)
     gene            809..882
                     /locus_tag="RPH49_002713"
     tRNA            809..882
                     /locus_tag="RPH49_002713"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:843..845,aa:Pro,seq:tgg)
     gene            900..975
                     /locus_tag="RPH49_002714"
     tRNA            900..975
                     /locus_tag="RPH49_002714"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:933..935,aa:Ala,seq:tgc)
     gene            997..1070
                     /locus_tag="RPH49_002715"
     tRNA            997..1070
                     /locus_tag="RPH49_002715"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Met,seq:cat)
     gene            1099..1172
                     /locus_tag="RPH49_002716"
     tRNA            1099..1172
                     /locus_tag="RPH49_002716"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1133..1135,aa:Ile,seq:cat)
     gene            1182..1271
                     /locus_tag="RPH49_002717"
     tRNA            1182..1271
                     /locus_tag="RPH49_002717"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1218..1220,aa:Ser,seq:tga)
BASE COUNT          307 a          315 c          359 g          365 t
ORIGIN      
        1 taaatgtttt gcgaagcaaa atcactttta cttactatct agttttgaat gtataattta
       61 cattcatatg tctggtgact atagcaagga ggtcacacct gttcccatgc cgaacacaga
      121 agttaagctc cttagcgtcg atggtagtcg aacttacgtt ccgctagagt agaacgttgc
      181 caggcagttt taaatcggag aattagctca gctgggagag catctgcctt acaagcagag
      241 ggtcggcggt tcgaacccgt cattctccac catttattct tacatattgc cggcctagct
      301 caattggtag agcaactgac ttgtaatcag taggttgggg gttcaagtcc tctggccggc
      361 accatggaag agccattagc tcagttggta gagcatctga cttttaatca gagggtcaga
      421 ggttcgaatc ctctatggct caccatttgc gggtgtggcg gaattggcag acgcactaga
      481 cttaggatct agcgccttac ggcgtggggg ttcgactccc ttcacccgca tatgcagaag
      541 tagttcagcg gtagaataca accttgccaa ggttggggtc gcgggttcga atcccgtctt
      601 ctgctccatt tttatagtgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      661 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcaccattt tcaataaaaa
      721 catatgcgcc cgtagctcaa ttggatagag cgtttgacta cggatcaaga ggttatgggt
      781 tcgactccta tcgggcgcgt taattatacg ggaagtagct cagcttggta gagcacttgg
      841 tttgggacca aggggtcgca ggttcgaatc ctgtcttccc gatatactgt aattattatg
      901 ggggcttagc tcagctggga gagcgcctgc tttgcacgca ggaggtcagc ggttcgatcc
      961 cgctagtctc caccatatta tttacaaact atataaggcg gtgtagctca gctggctaga
     1021 gcgtacggtt catacccgtg aggtcggggg ttcgatcccc tccaccgcca ctatttatta
     1081 gttgtaaaat tatatttagg acctttagct cagttggtta gagctaacgg ctcataaccg
     1141 ttcggtcgca ggttcgagtc ctgcaaggtc catataattt tggaggaata cccaagtccg
     1201 gctgaaggga tcggtcttga aaaccgacag gggcttaacg gctcgcgggg gttcgaatcc
     1261 ctcttcctcc gttttactaa tggtctcgta gtgtagcggt taacacgcct gcctgtcacg
     1321 caggagatcg cgggttcgat tcccgt
//
LOCUS       DAPSKH010000149         1296 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPSKH010000149 DAPSKH010000000
VERSION     DAPSKH010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1296
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.156"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            89..226
                     /locus_tag="RPH49_002718"
     CDS             89..226
                     /locus_tag="RPH49_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125810.1"
                     /translation="MILIMLDSQLDGNVTAKELSESFKELVEEFESIEKAKKNSNSKD
                     K"
     gene            288..548
                     /locus_tag="RPH49_002719"
                     /pseudo
     CDS             288..548
                     /locus_tag="RPH49_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282612.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
     gene            597..944
                     /locus_tag="RPH49_002720"
                     /pseudo
     CDS             597..944
                     /locus_tag="RPH49_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002456552.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            955..1149
                     /locus_tag="RPH49_002721"
     CDS             955..1149
                     /locus_tag="RPH49_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125811.1"
                     /translation="MRIEDAYRKDVIITLLNNEEYEGFVTDYENEFESETGNLVVDIQ
                     TDFAVYSFDETEIKSIRLLK"
BASE COUNT          563 a          126 c          225 g          382 t
ORIGIN      
        1 ttacgcatat taatatcatt aatgatagcc atattgaaaa attattgaaa aaactttata
       61 gtataaatat gattaaatat aaagtgagat gattttaatt atgttagatt cacaattaga
      121 tggaaatgta actgcaaaag aattgagtga atcttttaaa gaattagttg aagaatttga
      181 aagtatagaa aaagcgaaaa agaattcaaa ttcaaaagat aaatagcatc ctttttagac
      241 agataaagag aaagtggtgc tatttttata cgctttttta actatttact gaaaatgcag
      301 aagcacaaaa gttaacatat ttaaaagaac ttggtgaaga tggcgaatat aaatatgttg
      361 ccaaaataga tagtaaaaca tctaaattat gtcattcact taacggaaaa atatttaaag
      421 ttaaagatat gataccaggt gtgaatgcgc cacctatgca tccttggtgt agaagtacca
      481 cagtgccaca tgttggcaat tggcgggaca agttctttaa agagcgtgaa ggtaaatatc
      541 aagtagaagt aaaagaagca taattacagg aaaaagctaa aaaccagatg aaagaaatga
      601 ttaaaaatgg taaaataaaa atagaaataa attgcggaaa ataaaataga tatatgttag
      661 gtcatcacct atataatgaa aataaaaaaa gagccatttt aaataataag aaattgccta
      721 gctatacaat actttctata gatttattga atgaattgtt aagagaaaaa atgtcaacag
      781 gcaatctaat attaagtgat gagcgatttg atttgaaaga gattattaat tttaatcaaa
      841 ttattggaaa aatacatatc gaaaatgtgt atattgaaac cagaaaggga aaagtgcatt
      901 attcgaagac aggtgctcat atagtacctt atattgataa gtaggtgaaa agtattgaga
      961 attgaagatg catatcgtaa agatgttatt atcacgcttt tgaataatga agaatacgaa
     1021 gggtttgtaa ctgactatga aaatgaattc gagagcgaaa caggaaatct tgttgtagat
     1081 atacagactg attttgctgt ttattcgttt gatgaaactg agataaaaag tattagatta
     1141 ttaaaataat tacaaaatag catcctttct acaaaaagct aaaaaagaaa tgcttgaaat
     1201 gataagtaat ggtaaaatga cgatgaaatt gaataatgtt aagcaaaagc gtcatatttt
     1261 atgcacaaat gaatataata ataagaaaaa taattc
//
LOCUS       DAPSKH010000150         1234 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPSKH010000150 DAPSKH010000000
VERSION     DAPSKH010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1234)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1234)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1234
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.157"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(24..962)
                     /locus_tag="RPH49_002722"
     CDS             complement(24..962)
                     /locus_tag="RPH49_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDY5125812.1"
                     /translation="MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQ
                     AINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQP
                     EYLKQQVENSLKRLQTDYIDLYYIHFPDDNTPKDQAVAALQELKEQGKIKAIGVSNFT
                     LDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDE
                     NTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVII
                     PGAKLAEQVVENIKAADIVLSDDEIQYIDELFPIED"
BASE COUNT          392 a          232 c          175 g          435 t
ORIGIN      
        1 tatcaccatt aaatacaatt catttagtct tcaatcggaa acagttcatc gatatattga
       61 atctcatcat ctgataaaac gatatctgca gctttaatat tttcaacgac ttgttctgca
      121 agttttgcac caggaataat cacatcgata gctggtctcg ttaaataaaa tgctaataca
      181 atgttcgcaa ttgaagtttg atgtgctgca gctatgcttt ccaaagcttt tacgcgacgc
      241 acattttctt caaatacacc tggtttaaaa tcacgacgtg tagtacgatg gtcactaaat
      301 ttagtgttct catcatattt tccagctaaa ataccggatg ctaatgggaa atatggaata
      361 aatgtgattt ggtgatcaac acaatattgt aatactgcct cattttcgcg atgcaataaa
      421 ttatattcta actgtacaac atcaacgtaa ccatctttat ttgcttcttt aagttgatct
      481 aatgtgaaat ttgatacacc aatggcttta atcttccctt gttccttaag ctcttgtaat
      541 gctgcaactg cttgatcttt cggagtgttg tcatccggaa aatgaatata atataaatcg
      601 atataatcag tttgtagacg tttcaaacta ttctcaactt gttgttttaa atattcaggt
      661 tgattgttct gatgtacttc ttgattttca tcaaattcat gagacccttt tgtagcaatt
      721 ttaatttgct ctcgcggata ttctttaaca acttctccaa ccaattcttc tgatcgttct
      781 ggcccataaa tatatgccgt atctaataaa ttaataccat gattaatggc ttgacgaaca
      841 acatcttttc cttgttcttc atctaagttc ggatataaat tatgcccacc tactgcgttc
      901 gtcccaagtg cgattggaaa cacttcaaca tcagatttac ctaagtttac aaattgcttc
      961 attagaccca gctccttatc tttataactt ttccactatc acactaccat gatttaatac
     1021 aacttccaaa tgttagaatt agagcttgaa tttaagcggt gtaataggaa aacgttatat
     1081 aaaactcagt taaaataagt attgcttaaa ttgatatgca tatagcgcga ttgctcgttg
     1141 acctttaaat tacatgtact tttgaatcag aaattgaaaa acatttaaga acgacaacat
     1201 taaagccatt acaaatttaa ttagaaatac tata
//
LOCUS       DAPSKH010000151         1208 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPSKH010000151 DAPSKH010000000
VERSION     DAPSKH010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1208
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.158"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(250..1143)
                     /locus_tag="RPH49_002723"
     CDS             complement(250..1143)
                     /locus_tag="RPH49_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDY5125813.1"
                     /translation="MKKTILLTMTTLTLFSMSPNSAQAYTNDSKTLEEAKKAHPNAQF
                     KVNKDTGAYTYTYDKNNAPNNNHQNQSRTNDNHQHANQRDFNNNQYHSSLSGQYTHIN
                     DAIDSHTPPQTSPSNPLTPAIPNVEDNDDELNNAFSKDNKGLITGIDLDELYDELQIA
                     EFNDKAKTADGKPLALGNGKIIDQPLITSKNNLYTAGQCTWYVFDKRAKDGHTISTFW
                     GDAKNWAGQASSNGFKVDRHPTRGSILQTVNGPFGHVAYVEKVNIDGSILISEMNWIG
                     EYIVSSRTISASEVSSYSYIH"
BASE COUNT          346 a          185 c          223 g          454 t
ORIGIN      
        1 aattaataga attttagtta taataatgtt taataagtta ttgaaaatct aataaactac
       61 aaaaaatagt ttgattacat aatgattctt gaaaaatgtc ggttaacttt aaggtgacaa
      121 gttattgcaa ttttgaaggt aaacatcata ttttataatc gaataacata caaaataaag
      181 cgaccaattt tgcagtgtta cgaattgtaa actgcgaact ggtcgctttt tattgatgtc
      241 atgattaatt taatggatgt aactatatga tgaaacttct gaagcagaga tggttcttga
      301 tgaaacgata tattcaccaa tccaattcat ttctgaaatt agaatacttc catcaatatt
      361 aactttctca acgtaggcta catgaccaaa tggaccgttt actgtttgta aaattgatcc
      421 tcgtgttggg tgtctatcta ctttgaagcc attgcttgaa gcttggcctg cccagttttt
      481 agcatctccc caaaatgtac taatcgtgtg tccatctttg gcacgtttat caaagacata
      541 ccatgtacat tgtccagcag tatataagtt gttcttactt gtgataagag gctgatcaat
      601 gattttaccg ttacctaatg ctaaaggttt accgtcagca gtctttgctt tgtcattaaa
      661 ttcggcgatt tgtaattcgt catacaattc gtctaaatcg atgcctgtaa taagcccttt
      721 gttatctttt gaaaaagcgt tatttaattc atcgtcattg tcttcgacat tcggtatggc
      781 tggtgtcaaa ggattgcttg gtgacgtttg aggcggtgtg tgtgaatcaa ttgcgtcatt
      841 aatgtgcgta tactgaccac ttaatgaaga atggtactga ttgttgttaa aatcacgttg
      901 atttgcgtgt tgatgattgt cgtttgtacg tgactgattt tgatgattgt tgtttggcgc
      961 gttgtttttg tcataagtat aagtatacgc gccggtgtct ttattcactt tgaactgtgc
     1021 gtttgggtgt gctttctttg cttcttctaa tgttttgcta tcattcgtgt atgcttgagc
     1081 cgagttaggc gacatactaa ataaagtaag agttgtcatc gtcagtaaaa ttgttttctt
     1141 cataataacc atttaatcct ttatgtattt aatttaattt tagtatacac atttatatta
     1201 caaaaatg
//
LOCUS       DAPSKH010000152         1175 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPSKH010000152 DAPSKH010000000
VERSION     DAPSKH010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1175
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.159"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            49..>1175
                     /locus_tag="RPH49_002724"
     CDS             join(49..295,295..>1175)
                     /locus_tag="RPH49_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558209.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDY5125814.1"
                     /translation="MTRERRSFSSEFKLQMVRLYENGKPRNEIIREYDLTPSALGKWR
                     KQHQNTGTFNHQDNLSDEEKELIKLRKEVQHLKMENDIFKASSADHGTKIEVIQKNAH
                     QYSVSAMCKVLKIPRSTYYDSIKRRDNKNTKDDSNVERAVINIFNSNRKVFGTRRIKN
                     NLNDKGLTVSRRKIARIMKKHNLVSVYTKAKYKNHPKETNEKRIKNHLNRAFNREQPM
                     ETLVSDLTYVKVGGTWHYICLFIDLFNREIVGYSAGKNKDANLVSKAISRINHNLEQI
                     KLFHTNRGKEFDNHLIDEVLETFKIKRSLSTKGCPYDNAVAEATMKAMKTEFVKQMQF
                     ENLEQLETELFDYVNWYNNFRPHSSLQYLTPVAFKNLHMKTV"
BASE COUNT          498 a          155 c          200 g          322 t
ORIGIN      
        1 ttctatgaga atagatattg ttaatttaag aaagtaggcg attttattat gacaagagaa
       61 agaagatcat ttagttcaga gtttaagtta caaatggtta gattatatga aaatggtaag
      121 cctaggaatg aaattatacg cgagtatgat ttaacacctt cggcgttagg aaaatggaga
      181 aagcaacatc aaaacacggg tacattcaat caccaagata acttatcaga tgaagaaaaa
      241 gagctgatta aattacgtaa agaagttcaa catttaaaaa tggagaacga tattttaaag
      301 caagcagcgc tgatcatggg acgaaaatag aagtcattca aaagaatgca catcaatatt
      361 cagtatcagc aatgtgtaaa gtcctaaaaa taccaagaag tacttattat gattctataa
      421 aaagaagaga taataaaaac actaaagatg attcaaacgt agaacgtgct gtcataaata
      481 tttttaattc taatagaaaa gtctttggta caagacgaat taaaaataat ttaaatgaca
      541 agggtcttac tgtatcaagg cgaaagatag ctcgtatcat gaaaaaacat aatctagttt
      601 ctgtttatac gaaagctaaa tacaaaaatc atccaaaaga aactaatgaa aaacgaatta
      661 aaaatcattt gaatcgcgct tttaatagag aacaaccaat ggagacatta gtaagtgatt
      721 tgacatatgt aaaagtcgga ggaacatggc attacatatg tttatttata gatctattta
      781 atagagaaat tgttggttac agtgcaggta aaaataagga cgcaaattta gtatcaaaag
      841 caatcagcag aataaatcat aatcttgaac aaatcaaact attccacact aatagaggca
      901 aagaatttga taatcatttg atagatgaag tcctagaaac atttaaaatc aaacgttcat
      961 taagtaccaa aggttgtcct tatgataacg cagttgcgga agcaacgatg aaagcaatga
     1021 aaaccgaatt tgtaaaacaa atgcaatttg aaaacttaga acagttagaa acagaattat
     1081 ttgattatgt aaattggtac aacaatttta gaccacattc ttcattacag tatttgacgc
     1141 cagtggcatt taaaaatcta cacatgaaaa ctgtc
//
LOCUS       DAPSKH010000153         1105 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPSKH010000153 DAPSKH010000000
VERSION     DAPSKH010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1105
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.160"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..>1105)
                     /locus_tag="RPH49_002725"
     rRNA            complement(<1..>1105)
                     /locus_tag="RPH49_002725"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          242 a          326 c          239 g          298 t
ORIGIN      
        1 gcacgtgtgt agcccaaatc ataaggggca tgatgatttg acgtcatccc caccttcctc
       61 cggtttgtca ccggcagtca acttagagtg cccaacttaa tgatggcaac taagcttaag
      121 ggttgcgctc gttgcgggac ttaacccaac atctcacgac acgagctgac gacaaccatg
      181 caccacctgt cactttgtcc cccgaagggg aaggctctat ctctagagtt gtcaaaggat
      241 gtcaagattt ggtaaggttc ttcgcgttgc ttcgaattaa accacatgct ccaccgcttg
      301 tgcgggtccc cgtcaattcc tttgagtttc aaccttgcgg tcgtactccc caggcggagt
      361 gcttaatgcg ttagctgcag cactaagggg cggaaacccc ctaacactta gcactcatcg
      421 tttacggcgt ggactaccag ggtatctaat cctgtttgat ccccacgctt tcgcacatca
      481 gcgtcagtta cagaccagaa agtcgccttc gccactggtg ttcctccata tctctgcgca
      541 tttcaccgct acacatggaa ttccactttc ctcttctgca ctcaagtttt ccagtttcca
      601 atgaccctcc acggttgagc cgtgggcttt cacatcagac ttaaaaaacc gcctacgcgc
      661 gctttacgcc caataattcc ggataacgct tgccacctac gtattaccgc ggctgctggc
      721 acgtagttag ccgtggcttt ctgattaggt accgtcaaga tgtgcacagt tacttacaca
      781 tatgttcttc cctaataaca gagttttacg atccgaagac cttcatcact cacgcggcgt
      841 tgctccgtca ggctttcgcc cattgcggaa gattccctac tgctgcctcc cgtaggagtc
      901 tggaccgtgt ctcagttcca gtgtggccga tcaccctctc aggtcggcta tgcatcgttg
      961 ccttggtaag ccgttacctt accaactagc taatgcagcg cggatccatc tataagtgac
     1021 agcaagaccg tctttcactt ttgaaccatg cggttcaaaa tattatccgg tattagctcc
     1081 ggtttcccga agttatccca gtctt
//
LOCUS       DAPSKH010000154         1084 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPSKH010000154 DAPSKH010000000
VERSION     DAPSKH010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1084
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.162"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..100)
                     /locus_tag="RPH49_002726"
     CDS             complement(<1..100)
                     /locus_tag="RPH49_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding protein"
                     /protein_id="HDY5125815.1"
                     /translation="MKNKLIAKSLLAIAAIGITTTTIASTADASEGY"
     gene            complement(359..865)
                     /locus_tag="RPH49_002727"
     CDS             complement(359..865)
                     /locus_tag="RPH49_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125816.1"
                     /translation="MIIKILTILLLLCILSYLVTNRKKPFLFLKTLFMGVVFIFIGYI
                     SLAISAVIIYGIIQFITIDFGSFFLMGIILILISSIFQLFIVRLLFRKKNVDLTEVVV
                     LEHLIQWFLVYFAIYQAVNEKMDINDINIDNFQSVFFDVSNLNLVILPTLIISWVTIF
                     NYRMRSYK"
BASE COUNT          411 a          171 c          116 g          386 t
ORIGIN      
        1 cgtatccttc gctcgcatct gctgttgacg caattgtagt tgtagtaata ccaattgccg
       61 ctattgctaa taaagatttt gctatcaatt tatttttcat gttaattatc ctccaaatca
      121 ttatcttaca tttattaagt tatcctattt atacaacttt tgaaattaac taattattaa
      181 ttaactataa acactttata atatagacaa aatatagcta tctatcttgt gactcatcag
      241 cacttataca ctagtcaaaa aattcatgcc tctacttttt cgaatttcaa aaataaaacc
      301 acacaacaaa aaagacacca tttgaatgtt ggtgtctgat ggtataattt catagatttt
      361 atttgtaact tctcattcta tagttaaata ttgtgaccca gctaatgatt aacgttggta
      421 gaattactaa attcaaatta gacacgtcaa aaaagacaga ttggaaattg tcgatattaa
      481 tatcattaat gtccattttt tcatttactg cttgatagat cgcaaagtaa actaagaacc
      541 attgaattaa atgttctaaa acgacaacct ctgtcaaatc tacattcttt tttctaaaaa
      601 gtaatctaac tataaataat tggaatatac ttgaaatcaa gatcaatata atacccatta
      661 agaaaaaact accaaaatca attgtgataa attgaataat accataaata attacggcag
      721 atattgccag tgaaatatat cctataaaga taaataccac acccataaag agtgtcttta
      781 agaacagaaa aggcttcttt ctatttgtaa ccaaatagct caatatacaa agtagtaata
      841 gaattgttaa aattttaatt atcatcgttt gacctcaata tatttattta tatctttatt
      901 attgaccacg aaaaaataac aatcacttaa gtgattgcca ataatactca atgcctactc
      961 tatagtaatc ttggcacgtg attttacact attttatcta tttaaaaatg taagtgttga
     1021 attatgctta cttcgaaaat gcataattca actaaatagt ataattttta acttatatat
     1081 taat
//
LOCUS       DAPSKH010000155         1064 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPSKH010000155 DAPSKH010000000
VERSION     DAPSKH010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1064
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.163"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            404..1051
                     /locus_tag="RPH49_002728"
     CDS             404..1051
                     /locus_tag="RPH49_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002504895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDY5125817.1"
                     /translation="MKNILKVKEPKKKLEVLTNVEVKKLLGAANNIRDKFLIQLLYET
                     GLRIGEVLSLRIDDIKFDFRKGHQIVLKNRFNSNGTYLKTGERKIFISQSLIDLYDDY
                     VYEIIDELSICSDYLFVKIKGRNVGEAMHYSDIYSLFKRLKHKTSINVHPHLFRHTHA
                     TVFYNETKDIKQVQERLGHSNIQTTINLYVHPTEEDIREDWNKVKHQFQVFNKGE"
BASE COUNT          428 a          121 c          165 g          350 t
ORIGIN      
        1 tgaacctata gtagatgcag taagatattt gaagtatctg gatagtgtta ataaaagttt
       61 aaataccaag aaaacctatg cctatgcact aaaaaaattt tttgtttact tagaaagtaa
      121 aaagatatgc tataaagaag ttagttttga taactttgtt gattttataa gatggatgaa
      181 aacacctttt gaatatgaga atgtcctctc ttatcaccga aaaggaaaaa gcattagtcc
      241 taagacaatt aatctgacta ttactgtagt atctaatttt tatgattatc tctataggag
      301 caaaaaatta gatgttaatt tctatgattt tatacatacg gaaagtaaat actctaaaaa
      361 atataaaagt ttcatgcatc acgtaaacaa ggactatgga atgttgaaaa atattttgaa
      421 agtaaaagaa ccaaagaaaa aactagaagt gttaaccaat gttgaggtta agaaattatt
      481 aggagcagct aataatatta gagataaatt cttaatacaa ttattatatg aaacaggatt
      541 gcgtataggt gaggtattat cattacgcat tgatgatatc aaatttgatt ttagaaaagg
      601 tcaccaaata gttttgaaaa atagatttaa tagcaatggt acttatttaa aaactggtga
      661 aagaaaaata tttatttctc aatcgttaat tgatttatat gacgattatg tgtacgaaat
      721 aattgacgaa ctttccatat gttctgatta tctttttgta aaaataaagg gtagaaatgt
      781 aggagaagct atgcattata gtgatatata ttcattattt aaaaggctaa aacataaaac
      841 atctataaat gttcaccccc atttatttcg ccatacacat gcaactgttt tttataatga
      901 aactaaggat attaaacaag ttcaagaaag actcggtcat agtaatatac aaacgactat
      961 taatttatat gttcatccca ctgaagaaga tatacgtgaa gattggaata aagttaagca
     1021 tcaatttcaa gtttttaata aaggggaata actatgtcaa tacc
//
LOCUS       DAPSKH010000156         1035 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPSKH010000156 DAPSKH010000000
VERSION     DAPSKH010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1035
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.164"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(63..146)
                     /locus_tag="RPH49_002729"
     tRNA            complement(63..146)
                     /locus_tag="RPH49_002729"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(110..112),aa:Leu,seq:caa)
     gene            complement(185..259)
                     /locus_tag="RPH49_002730"
     tRNA            complement(185..259)
                     /locus_tag="RPH49_002730"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(224..226),aa:Gly,seq:tcc)
     gene            complement(363..437)
                     /locus_tag="RPH49_002731"
     tRNA            complement(363..437)
                     /locus_tag="RPH49_002731"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(402..404),aa:Gly,seq:tcc)
     gene            complement(445..518)
                     /locus_tag="RPH49_002732"
     tRNA            complement(445..518)
                     /locus_tag="RPH49_002732"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(484..486),aa:Cys,seq:gca)
     gene            complement(524..595)
                     /locus_tag="RPH49_002733"
     tRNA            complement(524..595)
                     /locus_tag="RPH49_002733"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(561..563),aa:Gln,seq:ttg)
     gene            complement(607..679)
                     /locus_tag="RPH49_002734"
     tRNA            complement(607..679)
                     /locus_tag="RPH49_002734"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(644..646),aa:His,seq:gtg)
     gene            complement(682..755)
                     /locus_tag="RPH49_002735"
     tRNA            complement(682..755)
                     /locus_tag="RPH49_002735"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(721..723),aa:Trp,seq:cca)
     gene            complement(771..851)
                     /locus_tag="RPH49_002736"
     tRNA            complement(771..851)
                     /locus_tag="RPH49_002736"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(815..817),aa:Tyr,seq:gta)
     gene            complement(857..932)
                     /locus_tag="RPH49_002737"
     tRNA            complement(857..932)
                     /locus_tag="RPH49_002737"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(897..899),aa:Thr,seq:tgt)
     gene            complement(940..1012)
                     /locus_tag="RPH49_002738"
     tRNA            complement(940..1012)
                     /locus_tag="RPH49_002738"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(977..979),aa:Phe,seq:gaa)
BASE COUNT          306 a          246 c          238 g          245 t
ORIGIN      
        1 aaaaagaaac cttgttttac aaggtttcta atacgttatg ttatgtaaat aacagttaat
       61 tataccggtg gtcggggtcg aaccgacact ccacaagtgg aacgggattt tgagtcccgc
      121 gcgtctgcca attccgccac accggcttaa tggtaaacaa aaaacttccc tttggaagca
      181 attatggagc ggaagatagg atttacacct atacctcgtt ccgggaagga acgtgttcta
      241 aaagttgaac tactcccgca aatattaaat tatggagcgg aagataggat ttacacctat
      301 acctcattcc aggaaggaat gtattctaag agttgaaata ctcccgcatt attattaaat
      361 tatggagcgg aagataggat ttgcacctat acctcgttcc gggaaggaac gtgttctaaa
      421 agttgaacta ctcccgcata aacctggagg cggcaaccgg atttgaaccg gtgataaagg
      481 ttttgcagac ctctgcctta ccacttggct atgccgccaa taactgggct agctggattc
      541 gaaccaacga gtgacggagt caaagtccgt tgccttaccg cttggctata gcccattaat
      601 aataagggcg gctgaagggg atcgaaccct cgaatgtcgg aaccacaatc cgatgtgtta
      661 accacttcac cacagccgcc atggcagggg cagtaggaat cgaacccaca ccaaaggttt
      721 tggagacctc tattctaccg ttgaactatg cccctattaa aaataataaa tggagggggg
      781 cagattcgaa ctgccgaacc cgaaggagcg gatttacagt ccgccgcgtt tagccacttc
      841 gctacccctc cataaatggt gccggccaga ggacttgaac ccccaaccta ctgattacaa
      901 gtcagttgct ctaccaattg agctaggccg gctaagaaat ggttcaggac agagtcgaac
      961 tgccgacaca tggagcttca atccattgct ctaccaactg agctactgaa ccataataaa
     1021 aatgtaatga tggcg
//
LOCUS       DAPSKH010000157         1028 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPSKH010000157 DAPSKH010000000
VERSION     DAPSKH010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.165"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            7..441
                     /locus_tag="RPH49_002739"
     CDS             7..441
                     /locus_tag="RPH49_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016170817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125818.1"
                     /translation="MKKVIGLLLVSTLALTACGEKEKPKKEENKKSQTQKHKDSKPKT
                     QQEKMKKVEDKNPPNNSIQNNSNNQNQSQNNQLNNNSDPSNNTPANINKNDSQNTNLN
                     DEYVVSPGWTKDEQAKAFEEYKKGKEDEARAGASAVPGANIN"
     gene            470..865
                     /locus_tag="RPH49_002740"
     CDS             470..865
                     /locus_tag="RPH49_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125819.1"
                     /translation="METNKTIDLMNYVEFPKRYTEAKGKLVAQPITTINSARRVENED
                     MTVCYILDQDDDVMDFIFDRDIITVYCPGNGTATDEYFCEIIFNSDDTFTLKRLSNYV
                     TIKDRSYPMSKINDVNITGKVVRLFRDFK"
BASE COUNT          466 a          153 c          166 g          243 t
ORIGIN      
        1 atacatatga aaaaagtaat cggactgcta ctagtaagta cattagcttt aacagcttgt
       61 ggtgaaaaag aaaaaccaaa aaaagaagaa aataaaaagt cacaaacaca aaaacacaaa
      121 gatagcaaac caaaaacgca acaagaaaaa atgaaaaaag ttgaagataa aaatccacct
      181 aataatagca tacaaaataa ttcaaacaat caaaaccaat cacaaaacaa tcaacttaat
      241 aataattcag atccatctaa taatactcct gcaaatataa ataaaaacga ttcacaaaat
      301 actaatttaa atgatgagta tgtcgtttcg cctggctgga ctaaagatga acaagctaaa
      361 gcttttgaag agtacaaaaa aggaaaagaa gacgaagcaa gagctggtgc tagcgcagta
      421 ccaggagcca atattaacta ataaaacaat ataagaaaga agagctaata tggaaacaaa
      481 taaaacaatc gatttaatga attatgtgga atttccaaaa agatacacag aggcaaaagg
      541 caaattagtt gcacaaccaa taactactat aaatagcgca agaagagttg aaaatgaaga
      601 tatgactgtt tgctacattt tagatcagga tgatgatgta atggacttta tctttgacag
      661 agatataatt actgtttact gtcctggaaa cggaactgcg actgatgaat atttttgtga
      721 aattatattt aactcagatg acacatttac cctaaagcga ttatctaatt acgttaccat
      781 taaagataga agctacccaa tgtcaaaaat aaatgacgta aacattacgg gcaaagtcgt
      841 cagattattt agagatttta aataaacttg gctttaatta cgattaaaag tacctatata
      901 gcgtgacgag aaaaaggatt aaaaaaaaat tcaaaaacgc ctactagtgt agacgttgaa
      961 tggtggtgag aattttatgg cggataaaaa caaaaaacaa gaagctaccc gtagtaaccc
     1021 aataaaca
//
LOCUS       DAPSKH010000158         1024 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPSKH010000158 DAPSKH010000000
VERSION     DAPSKH010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1024)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1024)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.166"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..311)
                     /locus_tag="RPH49_002741"
     CDS             complement(<1..311)
                     /locus_tag="RPH49_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDY5125820.1"
                     /translation="MAKLLIMSIVSFCFIFLLLLFFRYILKRYFNYMLNYKVWYLTLL
                     AGLIPFIPIKFSFFKFNNLNNQEPTVESNSHNLNPNINTTKPVHEFTTDIHKINWDSI
                     D"
     gene            418..>1024
                     /locus_tag="RPH49_002742"
     CDS             418..>1024
                     /locus_tag="RPH49_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDY5125821.1"
                     /translation="MKKLILLIAIALVLSACNSTSSHAKELNNLEKKYNANIGVYALD
                     TKSGKEVKFNADKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEK
                     YVGKDITLKELIEASMKYSDNTANNKIINEIGGIKKIKKRLKKLGDKVTNPVRYEIEL
                     NYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLM"
BASE COUNT          430 a          116 c          144 g          334 t
ORIGIN      
        1 ttatctattg aatcccaatt aatcttatgg atgtctgttg taaactcatg aacaggttta
       61 gtggtattta tgttaggatt caaattgtgt gaattacttt caactgtggg ctcttgatta
      121 ttcaaattat taaatttaaa aaaagagaat ttaataggga tgaaaggaat taatcctgca
      181 agaagagtta gataccaaac tttataattt aacatataat taaaatagcg ttttaatatg
      241 tacctaaaaa ataataacaa tagaaatata aaacaaaagc ttactatgct cattattaat
      301 aacttagcca tttcaacacc ttctttcaaa taattataat aaactattga cgcgaatatt
      361 acaattgtaa tattattgat ttatagaaat tacaactgta atattggagg gtatattttg
      421 aaaaagttaa tacttttaat tgcaattgct ttagttttaa gtgcatgtaa ttcaaccagt
      481 tcacatgcta aagagttaaa taatttagaa aagaaatata atgctaatat tggtgtctat
      541 gcattagata ctaaaagtgg taaggaagta aaatttaatg ccgataagag atttgcctat
      601 gcttcaactt caaaagcgat aaatagtgct attttgttag aacaagtacc ttataataag
      661 ttaaataaaa aagtacatat taacaaagat gatatagttg cttattctcc tattttagaa
      721 aaatatgtag gaaaagatat cactttaaaa gaacttattg aggcttcaat gaagtatagt
      781 gataatacag caaacaataa aattataaac gaaatcggtg gaatcaaaaa aattaaaaaa
      841 cgtttaaaaa aattgggaga taaagtaaca aatccagtta gatatgaaat agaattaaat
      901 tactattcac caaagagcaa aaaagatact tcaacgcctg ctgctttcgg caagacttta
      961 aataaactta tcgcaaatgg aaaattaagc aaaaaaaata aaaatttctt acttgattta
     1021 atgt
//
LOCUS       DAPSKH010000159         1003 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPSKH010000159 DAPSKH010000000
VERSION     DAPSKH010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.167"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            134..568
                     /locus_tag="RPH49_002743"
     CDS             134..568
                     /locus_tag="RPH49_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAP domain-containing protein"
                     /protein_id="HDY5125822.1"
                     /translation="MKLKSFITVTLALGMIATTGATVASNEVSAAEKDKQPATQKAKE
                     MQNVPYTIAVDGIMAFNQSYLNLPKDSQLSYLDLGNKVKALLYDERGVTPEKIRNAKS
                     AVYTITWKDSSKKEVDLKKDSYTANLFDSNSIKQIDINVKTK"
     gene            complement(825..>1003)
                     /locus_tag="RPH49_002744"
     CDS             complement(825..>1003)
                     /locus_tag="RPH49_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDY5125823.1"
                     /translation="LVTFFWALLLMQMVNFVLNSLVGGDSLNLVNPIIMAVLFTIFTA
                     IFAAVIKPPKDSSQ"
BASE COUNT          392 a          141 c          153 g          317 t
ORIGIN      
        1 atagctttta cattaattaa aatttatttt taaaaacaag taaacaattt acatacttat
       61 aatttttgaa acttttcaat ttgtgttata ttgattttgt aagatacttt aactcacaaa
      121 ggagagagat tatatgaaat taaaatcatt tataactgta actttggcac tgggcatgat
      181 cgcaacgact ggcgctactg tggcaagtaa tgaggtatct gcagcagaaa aggacaaaca
      241 accagcaact caaaaagcta aagaaatgca aaatgttcca tatacaattg cagtagatgg
      301 cattatggct ttcaatcaat cttacttaaa tttaccaaaa gatagccaat tatcatattt
      361 agatttagga aataaagtta aagctttatt atatgatgaa cgcggtgtaa cacctgagaa
      421 gattcgaaat gcaaaatctg ccgtttacac gattacttgg aaagatagta gtaaaaaaga
      481 agtggatctt aagaaagata gctacacagc aaacttgttt gattcaaatt caattaaaca
      541 aattgatatt aatgtaaaaa ctaaataaac acttaaaatt atcaaattca acatgaagca
      601 tttaatttta cagtgatgat tataatataa ttgccttgat acaaagatta ctcgtaaatg
      661 acatctttgt attaaggctt tttctaaatt taaaagtgat gggttagagg tcattgagct
      721 ttaaaatatt caaaatacaa aacattaatg gccaaaaata aaagccgcct ttatctgggc
      781 agcttcaata ataagaaaga catatttcat tttatactaa atagttattg tgatgaatct
      841 ttcggcggtt taattactgc agcaaaaatt gctgtgaaaa tcgtgaacaa tactgccatg
      901 ataattggat tcactaaatt taagctgtct ccacctacta ggctattaag tacaaagtta
      961 accatttgca ttaataataa tgcccaaaag aatgttacga ggt
//
LOCUS       DAPSKH010000160          982 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPSKH010000160 DAPSKH010000000
VERSION     DAPSKH010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..982
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.168"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..496)
                     /locus_tag="RPH49_002745"
     CDS             complement(<1..496)
                     /locus_tag="RPH49_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhB/YbcL family Raf kinase inhibitor-like
                     protein"
                     /protein_id="HDY5125824.1"
                     /translation="MKINTEFKGNNIPYEYAAGADISDLINGNPIKSFPFEITELPKD
                     TKYLAWSLIDYDAIPVCGFAWIHWSVANVSVTRDSISIKPDLSRTKGDYVQGKNSFTS
                     GLLADDFSEIENHYVGPTPPDQDHQYELTVYALDHSLNLKNGFYLNEFLKEVNQHKID
                     QTSIN"
     gene            complement(474..>982)
                     /locus_tag="RPH49_002746"
     CDS             complement(474..>982)
                     /locus_tag="RPH49_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125825.1"
                     /translation="SFLRALILGFFVGFIPINLYIDLKLNNVQFISVLTSYTIMGYIS
                     SRYLTRYLNYKFLSEICLVIFLIIYTFQNIIAITIAILFLGISSGLTRPQTINELSNS
                     SNLAAILNYAETLYFIFNIAFLLIGGYLYSIGTIQYLMLFMSLLTFIYLLTLFYLRRD
                     QHENQHRI"
BASE COUNT          364 a          141 c          134 g          343 t
ORIGIN      
        1 ggttaatact tgtttgatca attttatgtt gatttacttc ttttaaaaat tcattcaagt
       61 agaacccatt cttcaaattt aaagaatgat ctaacgcata aactgttaat tcatattgat
      121 gatcttgatc aggtggtgta ggtcctacat agtgattttc tatttctgaa aaatcatcag
      181 ctaacaaacc actagtgaag ctatttttac cttgtacata gtcgcccttt gttcttgata
      241 aatcaggttt aattgaaatt gaatcacgag tgacacttac attagcaacg ctccaatgaa
      301 tccatgcaaa tccgcaaact ggtattgcat cataatctat cagagaccat gcaagatatt
      361 tagtatcttt tggaagttct gttatttcaa acgggaatga tttaattgga ttgccattta
      421 ttaaatcact tatatctgcg cctgccgcat attcatatgg tatattattt cctttaaatt
      481 ctgtgttgat tttcatgttg atctctcctt aaataaaata atgttagtaa atatataaac
      541 gtcaataatg acataaataa cattaaatat tgaatagttc caattgaata taggtaacca
      601 ccaataagta aaaatgctat attaaaaata aagtacagtg tttccgcgta attaagtata
      661 gctgctaagt tactactatt tgaaagttca ttaattgtct gaggacgagt taagcctgaa
      721 gaaatcccta aaaataaaat agcgattgta attgcaataa tattttggaa tgtatatatt
      781 attaaaaata ttactaaaca aatttcagat agaaatttat aattcaaata tctagtcaag
      841 tagcgggaag aaatgtaacc cattattgta taactagtta atacagatat aaattgaacg
      901 ttattcagtt ttaaatcaat atacaaatta attggaataa atcctacaaa aaaccctaat
      961 attaaagctc ttaaaaaaga at
//
LOCUS       DAPSKH010000161          860 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPSKH010000161 DAPSKH010000000
VERSION     DAPSKH010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..860
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.169"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..390
                     /locus_tag="RPH49_002747"
     CDS             <1..390
                     /locus_tag="RPH49_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125826.1"
                     /translation="IDGYKESKLVSYIACGATGAGIGEELYDDILHEEVFFKEDETPS
                     NADFCILVNGDSMEPMLKQGTYAFIKKEDSIKDGTIALVVLDGVSLIKRVDICEDYIN
                     LVSLNPKYDDIKVASFSDIKVMGKVVL"
     gene            590..772
                     /locus_tag="RPH49_002748"
     CDS             590..772
                     /locus_tag="RPH49_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125827.1"
                     /translation="MKIKNCKIKKETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEF
                     ISQKLDGDKLTKEDSL"
BASE COUNT          334 a           98 c          155 g          273 t
ORIGIN      
        1 atagatggat ataaagagtc taaactagta tcgtatattg catgtggtgc aactggtgct
       61 ggcataggag aagaattata tgatgacata ttgcatgaag aagtattttt taaagaagac
      121 gaaacgccat caaatgctga tttttgtatt ttagttaatg gtgattcaat ggaacctatg
      181 ttaaaacaag gaacatacgc ttttattaag aaagaagatt ctattaaaga tggtacaatt
      241 gcactcgttg tattagatgg agtaagtctt atcaagcgtg tagatatatg cgaagactat
      301 attaatttgg tatctctaaa tccgaagtat gatgatatca aagtcgcttc gtttagtgat
      361 attaaagtaa tgggcaaagt tgtattgtga ttaataacgt atatttagcg ctttaatata
      421 aatataaaca aaggagaaat tgacatgaaa aaagcaatct taactttaag tcttatattt
      481 attacctact acctcacttt taaatatatg tggattaaag aattgaagta ttaatcatgc
      541 ttatttgaaa aagacgtcta tttcagcagt gtttgaaagg aagtttataa tgaaaataaa
      601 aaattgcaaa ataaaaaaag aaactatagt atatgaagtt ttaactagtg gtaatcaacc
      661 attcacttat gagttaccta aagatttatc gtcacataat gcgcgtaaat acttggaatt
      721 tatttcacaa aaattagatg gcgataagtt aaccaaagaa gattcattat gattttacta
      781 aacaaaaaac gcctacaagt gtagacgttg aatggtggtg agaattttat ggcggataaa
      841 aacaaaaaac aagaagctac
//
LOCUS       DAPSKH010000162          811 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPSKH010000162 DAPSKH010000000
VERSION     DAPSKH010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 811)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 811)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..811
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.170"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..425
                     /locus_tag="RPH49_002749"
     CDS             <1..425
                     /locus_tag="RPH49_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125828.1"
                     /translation="WQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAREAK
                     NRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRRREK
                     IIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            482..>811
                     /locus_tag="RPH49_002750"
     CDS             482..>811
                     /locus_tag="RPH49_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDY5125829.1"
                     /translation="MEEVLIDDNMVFDIDNLKGFLNDTSSFGFIAKENNKIIGFAYCY
                     TLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIKEYSKEIGCSEMFLITDKGNPRA
                     CHVYEKLG"
BASE COUNT          298 a          118 c          136 g          259 t
ORIGIN      
        1 gttggcaaag atgccaagtt cacttcctaa gaaatatctt taccaccatt cctaaaaaaa
       61 attcaaaatc tttcagagaa gctgttaaag gaatttttaa gttcacagat attaacttag
      121 cgcgtgaggc taaaaatcga ttgattcatg attatatcga tcaaccaaaa tattcaaaag
      181 cttgcgcatc attggatgat ggattcgaag acgcctttca atataccgta caaggaaatt
      241 cccacaatcg actaaagagt accaatctaa ttgaacgact gaatcaagaa gtacgcagaa
      301 gagaaaagat tattcgcatc ttccccaatc aaacatcagc caatcgctta attggagccg
      361 ttcttatgga cctacatgat gaatggattt attcttcaag aaaatacatc aattttgata
      421 agtagaaatg gtaaaaacat tgtatagcat tttacacagg agtctggact tgactgagtt
      481 tatggaagaa gttttaattg atgataatat ggtttttgat attgataatt taaaaggatt
      541 tcttaatgat accagttcat ttgggtttat agctaaagaa aataataaaa ttataggatt
      601 tgcatattgc tatacacttt taagacctga tggaaaaaca atgttttatt tacactcaat
      661 aggaatgtta cctaactatc aagacaaagg ttatggttca aaattattat cttttattaa
      721 ggaatattct aaagagattg gttgttctga aatgttttta ataactgata aaggtaatcc
      781 tagagcttgc catgtatatg aaaaattagg t
//
LOCUS       DAPSKH010000163          806 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPSKH010000163 DAPSKH010000000
VERSION     DAPSKH010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.171"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            81..>806
                     /locus_tag="RPH49_002751"
     CDS             81..>806
                     /locus_tag="RPH49_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDY5125830.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAI"
BASE COUNT          298 a          146 c          152 g          210 t
ORIGIN      
        1 taaaagtaaa aaggccatat aacagtcctt ttacggtaca atgtttttaa cgacaaaaac
       61 atacccagga ggacttttac atgacccaag tacattttac actgaaaagc gaagagattc
      121 aaagcattat tgaatattct gtaaaggatg acgtttctaa aaatatttta acaacggtat
      181 ttaatcaact aatggaaaat caacgaacag aatatattca agcaaaagaa tatgaacgaa
      241 cagaaaaccg acaaagtcaa cgaaatggct attatgagcg cagctttacg acacgtgtag
      301 gcacgctaga attaaaagta cccagaacac gtgatggcca tttttcaccc acagtgtttg
      361 aacgttatca acgaaacgaa aaagccctca tggcttcaat gttggaaatg tatgtatcag
      421 gcgtttcaac tcgtaaagta tcaaaaattg tggaagaact ttgtggtaaa tccgtctcta
      481 agtccttcgt ttctagctta acagaacagc tagaacctat ggttaacgag tggcagaatc
      541 gtttattatc agaaaaaaat tatccttact taatgaccga tgtactctat ataaaagtac
      601 gagaagaaaa tcgagtactc tcaaaaagct gtcatatagc gattggaata accaaagatg
      661 gcgaccgtga aattatcggc ttcatgattc aaagtggcga aagcgaagag acctggacaa
      721 cattttttga atacctaaaa gaacgcggtt tacaaggtac ggaactcgtt atttctgatg
      781 cgcacaaagg attagtctct gccatt
//
LOCUS       DAPSKH010000164          805 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPSKH010000164 DAPSKH010000000
VERSION     DAPSKH010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.172"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>805
                     /locus_tag="RPH49_002752"
     CDS             <1..>805
                     /locus_tag="RPH49_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HDY5125831.1"
                     /translation="ESNNWTHTWAGLDEKAKGQQVKYTVEELTKVKGYTTHVDNNDMG
                     NLIVTNKYTPETTSISGEKVWDDKDNQDGKRPEKVSVNLLANGEKVETVDVTSETNWK
                     YEFKNLPKYDEGKKIEYTVTEDHVKDYTTDINGTTITNKYTPGETSATVTKNWDDNNN
                     QDGKRPTEIKVELYQDGKATGKTATLNESNNWTHTWAGLDEKAKGQQVKYTVEELTKV
                     KGYTTHVDNNDMGNLIVTNKYTPETTSISGEKVWDDKDNQDGKRPEKVS"
BASE COUNT          368 a          118 c          171 g          148 t
ORIGIN      
        1 atgaatctaa taactggacc catacgtggg caggattaga tgaaaaagca aaaggtcaac
       61 aagtaaaata cacagtcgag gaattaacaa aggtcaaagg ttatacaaca catgtggata
      121 acaatgatat gggcaacttg attgtgacga ataaatatac gccagaaaca acatcaatta
      181 gcggtgaaaa agtatgggac gacaaagata atcaagatgg taagagacca gaaaaagtca
      241 gtgtaaattt attggctaac ggagagaaag tagaaacggt agatgtaaca tctgaaacaa
      301 actggaagta cgaatttaaa aacttaccga agtatgatga aggaaagaaa atagaatata
      361 cagtgaccga agatcacgta aaagactaca caacagacat caacggtacg acaataacga
      421 acaagtatac accaggagag acatcggcaa cagtaacaaa aaattgggat gacaataata
      481 accaagacgg aaaacgacca actgaaatta aagttgagtt atatcaagat ggaaaagcaa
      541 caggaaaaac ggcaacatta aatgaatcta ataactggac ccatacgtgg gcaggattag
      601 atgaaaaagc aaaaggtcaa caagtaaaat acacagttga agaattaaca aaagttaaag
      661 gctatacaac acatgtggat aacaatgata tgggtaactt gattgtgacg aataaatata
      721 cgccagaaac aacatcaatt agcggtgaaa aagtatggga cgacaaagac aatcaagatg
      781 gtaagagacc agaaaaagtc agtat
//
LOCUS       DAPSKH010000165          788 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPSKH010000165 DAPSKH010000000
VERSION     DAPSKH010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..788
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.173"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..62)
                     /locus_tag="RPH49_002753"
     CDS             complement(<1..62)
                     /locus_tag="RPH49_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HDY5125832.1"
                     /translation="MQALQTKSNIGEMFNIQEKE"
     gene            complement(78..320)
                     /locus_tag="RPH49_002754"
     CDS             complement(78..320)
                     /locus_tag="RPH49_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HDY5125833.1"
                     /translation="MIYNFDYSLLYERMAEYRYSQSSLANAIPISRTSINHKLQGKNL
                     FTQWEIKRICELLEIPPTKVGRYFFEQNVQKTVQIS"
     gene            484..>788
                     /locus_tag="RPH49_002755"
     CDS             484..>788
                     /locus_tag="RPH49_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDY5125834.1"
                     /translation="MNSFKDRLKQIMSERKISQSELSRRTGIGRNSISDYLNGKYEAK
                     QDKVFELAKALNVNEAWLMGFDISKNRKIENNDITSIYNKLTPPRQENVLNYANEQL"
BASE COUNT          258 a          128 c          122 g          280 t
ORIGIN      
        1 ttttcttttt cttgtatgtt gaacatttcg ccgatgttcg attttgtttg taatgcttgc
       61 attgttcgtt cctcctttta agatatttgt acagttttct gtacattttg ttcaaaaaaa
      121 tatctaccta cttttgttgg tgggatttct aataattcac agattcgttt tatttcccat
      181 tgtgtgaata aattttttcc ttgcaacttg tgattaatag atgtccttga aatagggatt
      241 gcgttcgcta aagaactttg gctatatcta tactctgcca ttctttcgta cagcaaacta
      301 taatcgaaat tgtatatcat aaactcacct cccttcttgt tcagttttct gtacaaatca
      361 attaaaacac ctttgtttaa ataagtcaac acataaaata catttttctg tacaatattt
      421 gttaaaaatt attgataatc gtcattgtac gtagtattat attcttagga ggtgttcaga
      481 aatatgaaca gttttaagga tagattaaag caaattatgt ctgaacggaa gatatctcaa
      541 tcagagctat caagaaggac tggtattggc agaaactcaa ttagcgatta tttaaatgga
      601 aaatatgaag cgaaacaaga caaagtcttt gaactagcaa aggctttaaa cgttaacgaa
      661 gcgtggctta tgggttttga tatttctaag aatagaaaaa ttgaaaataa cgacatcact
      721 tccatataca acaaactcac acctccccgc caagaaaacg tacttaacta tgcaaatgag
      781 caattaga
//
LOCUS       DAPSKH010000166          773 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPSKH010000166 DAPSKH010000000
VERSION     DAPSKH010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..773
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.174"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(32..256)
                     /locus_tag="RPH49_002756"
     CDS             complement(32..256)
                     /locus_tag="RPH49_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF739 family protein"
                     /protein_id="HDY5125835.1"
                     /translation="MCYDYSRLSGKIVEKYGTQYNFAIAMKLSERSLSLKLNGKVGWK
                     DSEIWKAIQLLDIPVEKIHLYFFKEKVHVI"
     gene            415..>773
                     /locus_tag="RPH49_002757"
     CDS             415..>773
                     /locus_tag="RPH49_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDY5125836.1"
                     /translation="MREKVSNRLKHIMKIRNLKQVDIINKSKPYQKKLGISLSKSTLS
                     QYINDVQSPDQDRIYLLSKTLNVGEAWLMGYDVDSYRVPDEERQDETIMSKINNIFSQ
                     LTPPRQENVLNYANEQL"
BASE COUNT          270 a          142 c          107 g          254 t
ORIGIN      
        1 gtgatttgtt ccattgtgtc cctccttaag ttcatataac atgaactttt tctttaaaaa
       61 aatataagtg tattttctct accggtatat ctagtagttg tatagctttc catatttcac
      121 tgtctttcca accaacttta ccgttgagtt ttaaggataa acttctctct gacaatttca
      181 tagcaattgc aaaattgtac tgagtgccat acttttctac tattttcccg ctcaaacgtg
      241 agtagtcgta acacataaaa gcacctcctc ttaagttcac gtatcatgaa cttaactata
      301 ctttacacct tgttttgaat caagtcaata caaaaattca tgatttatga acttttttgt
      361 tgaatttttg ttcaacaagc tttattatga agttatcaaa cggaggtgca ctaaatgaga
      421 gaaaaagttt caaatagact taaacacatt atgaaaataa gaaacttaaa acaagtagat
      481 atcattaata aatcgaaacc ttatcaaaag aaactaggta tatctttaag taaaagcact
      541 ttatctcaat atattaacga cgtacaatca cccgaccaag atagaattta cctactttct
      601 aaaactctga acgttggtga agcgtggctt atggggtatg atgtagattc ttatcgagtt
      661 cctgatgaag aacgtcaaga tgaaacgata atgtcaaaaa tcaataacat attttctcaa
      721 ctcacacctc cccgccaaga aaacgtactt aactatgcaa atgaacaatt gga
//
LOCUS       DAPSKH010000167          728 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPSKH010000167 DAPSKH010000000
VERSION     DAPSKH010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.175"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            19..>728
                     /gene="seu"
                     /locus_tag="RPH49_002758"
     CDS             19..>728
                     /gene="seu"
                     /locus_tag="RPH49_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031927818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type C1/U"
                     /protein_id="HDY5125837.1"
                     /translation="MKLFAFIFICVKSCSLLFMLNGNPKPEQLNKASEFTGLMDNMRY
                     LYDDKHVSETNIKSQEKFLQHDLLFKISGSKILKTEFNNKSLSDKYKNKNVDLFGTNY
                     YNQCYFSSDNMELNDGRLIEKTCMYGGVTEHDGNQIDKNNSTDNSHNILIKVYENERN
                     SLSFDIPTNKKNITAQEIDYKVRNYLLKHKNLYEFNSSPYETGYIKFIEGSGHSFWYD
                     LMPESGKKFYPTKYLLIY"
BASE COUNT          290 a           81 c          112 g          245 t
ORIGIN      
        1 aaatatggag ttgttgtaat gaagttattt gcctttatct tcatatgtgt taagtcttgc
       61 agcttactat ttatgttaaa tggcaatcct aaaccagaac aattgaataa agcgagtgaa
      121 ttcactggtc taatggataa tatgaggtat ttgtatgatg ataaacacgt atcagaaaca
      181 aacattaaat cccaagaaaa gtttttacaa catgatttat tatttaaaat aagtggttct
      241 aaaattttaa aaacagaatt taataataaa agcctttcgg ataaatataa aaataaaaac
      301 gtagatttgt ttgggacaaa ctattataat caatgctatt tttcatcgga taatatggaa
      361 ttaaatgatg gtagattaat tgaaaaaacg tgtatgtatg gcggtgtgac cgagcatgat
      421 ggaaatcaaa tagataaaaa taattcaact gataactctc ataatatctt aattaaagtt
      481 tatgaaaacg agagaaattc attatctttt gatataccta ctaataagaa aaacataaca
      541 gcacaagaaa tagattataa agttagaaac tatttactta agcataaaaa tttatatgaa
      601 tttaacagtt cgccttatga gactggctat ataaagttta tcgaaggaag tggtcattct
      661 ttttggtatg atttgatgcc tgaatctggt aaaaaatttt atccgactaa atatttacta
      721 atttataa
//
LOCUS       DAPSKH010000168          720 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPSKH010000168 DAPSKH010000000
VERSION     DAPSKH010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.176"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>720
                     /locus_tag="RPH49_002759"
     CDS             <1..>720
                     /locus_tag="RPH49_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125838.1"
                     /translation="YLNESYNISQVENSNFGERKHKLKQDFKKIVEVDILEGMSRELT
                     SFKQDVFSAIDDVKKNLVVIILIAPAAGVLILELNTIEEILEDLDKKLQRGIESLHDS
                     LDNVIKEMFKNLDHDFEDGVTEEMMKHLNVVNNNINFVKKQNDVYGEQITDIKNIMSH
                     QDATVMDGNLSINYSGEHMISGQVQSSNYLTRKMTILKNHIDNAVNKISDYVQETYNN
                     YFEPVLNYILEVIHSVETAVRH"
BASE COUNT          290 a           77 c          123 g          230 t
ORIGIN      
        1 tatttgaatg agagctataa tatttcacag gttgaaaatt ctaattttgg agaaagaaaa
       61 cataaactta aacaagattt taaaaagatt gtcgaagttg atatccttga aggaatgagt
      121 agggaattaa cttcttttaa acaggatgta tttagcgcaa ttgatgatgt caaaaaaaat
      181 cttgttgtaa taatcttaat agctccagca gctggagtcc ttattcttga attaaatact
      241 attgaagaaa ttcttgaaga tttagataaa aaattacaac gtggcataga aagtttacat
      301 gattcacttg ataacgtaat taaagaaatg tttaaaaatt tagatcatga ttttgaagat
      361 ggcgtgacag aggaaatgat gaagcattta aatgttgtga ataataatat aaattttgtg
      421 aaaaagcaaa atgatgtata tggagagcag ataaccgata ttaaaaatat aatgtctcat
      481 caagatgcaa cggtaatgga tggaaactta tctattaatt atagcggtga acatatgatt
      541 tcgggtcaag tacaatcttc taattattta accagaaaaa tgacaatttt aaaaaaccat
      601 attgataatg cagttaacaa aattagtgat tatgttcaag aaacttacaa taattatttt
      661 gaaccagtat taaactacat tcttgaagtt atacattcgg tagaaacagc tgtgagacat
//
LOCUS       DAPSKH010000169          663 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPSKH010000169 DAPSKH010000000
VERSION     DAPSKH010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..663
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.177"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>663
                     /locus_tag="RPH49_002760"
     rRNA            <1..>663
                     /locus_tag="RPH49_002760"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          162 a          145 c          211 g          145 t
ORIGIN      
        1 cgtggtggga gacagtgtca ggcgggcagt ttgactgggg cggtcgcctc ctaaaaggta
       61 acggaggcgc tcaaaggttc cctcagaatg gttggaaatc attcatagag tgtaaaggca
      121 taagggagct tgactgcgag acctacaagt cgagcagggt cgaaagacgg acttagtgat
      181 ccggtggttc cgcatggaag ggccatcgct caacggataa aagctacccc ggggataaca
      241 ggcttatctc ccccaagagt tcacatcgac ggggaggttt ggcacctcga tgtcggctca
      301 tcgcatcctg gggctgtagt cggtcccaag ggttgggctg ttcgcccatt aaagcggtac
      361 gcgagctggg ttcagaacgt cgtgagacag ttcggtccct atccgtcgtg ggcgtaggaa
      421 atttgagagg agctgtcctt agtacgagag gaccgggatg gacatacctc tggtgtacca
      481 gttgtcgtgc caacggcata gctgggtagc tatgtgtgga cgggataagt gctgaaagca
      541 tctaagcatg aagcccccct caagatgaga tttcccaact tcggttataa gatccctcaa
      601 agatgatgag gttaataggt tcgaggtgga agcatggtga catgtggagc tgacgaatac
      661 taa
//
LOCUS       DAPSKH010000170          650 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPSKH010000170 DAPSKH010000000
VERSION     DAPSKH010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.178"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            181..576
                     /gene="spxA"
                     /locus_tag="RPH49_002761"
     CDS             181..576
                     /gene="spxA"
                     /locus_tag="RPH49_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDY5125839.1"
                     /translation="MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQ
                     ILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLYSIIQDNPGLLRRPIILDNKRLQ
                     VGYNDDEIRRFLPRKVRTFQLQEAQRMVD"
BASE COUNT          237 a           92 c           92 g          229 t
ORIGIN      
        1 aatctttttt ataagtgtag aaacttatct gaaaaattag gtttttctca tttaatttta
       61 atgttagata gttataataa atagtaacga ttaagaattt tagaaaaaaa tgttttttct
      121 tgatctataa ctaaatttta agcaatgaat tttattcatt caaataggag agtgagatgt
      181 atggtaacat tatttacttc accaagttgc acatcttgcc gtaaagcgaa agcatggtta
      241 caagaacatg acattccgta tacggagcgt aatatttttt ctgaacattt aacaattgat
      301 gaaattaagc aaatattaaa aatgactgaa gacggtactg atgaaatcat ttctacacgt
      361 tctaaaacat accaaaaatt aaatgttgat attgattcac taccattaca agacttatat
      421 tcaatcattc aagataatcc tggcttatta cgtcgtccaa ttattttaga taataaacga
      481 ctacaagttg gttataatga tgacgagatt cgacgtttct tacctagaaa agttcgtacg
      541 ttccaattac aagaagcaca acgtatggtt gactaataac catttaacta tgtgtcatac
      601 tttactaaaa gatatgtcaa gcaacactat ttctatagtg ttgctttttt
//
LOCUS       DAPSKH010000171          572 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPSKH010000171 DAPSKH010000000
VERSION     DAPSKH010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.179"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>572
                     /gene="istA"
                     /locus_tag="RPH49_002762"
     CDS             <1..>572
                     /gene="istA"
                     /locus_tag="RPH49_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HDY5125840.1"
                     /translation="EQKFYYKRILWQYLKDKHGLTCAYSTFRAYILKHDEFNRYFMKG
                     YQQMSPKGTTRFETKAGHQAQFDWKEGINFKTKDNQIVSLNIGVLLLPYSRFVIMQVT
                     MNKSSDVLFNLLTQAFELMGGVPNELVTDNMKTVMDQPRTERTNGQINRRFKQFADDF
                     NFKVKPCIAGRPRTKGKVESIMKILDEIHA"
BASE COUNT          207 a           89 c          108 g          168 t
ORIGIN      
        1 gaacaaaagt tctactataa gcgtattctt tggcaatatt tgaaggataa acatgggtta
       61 acgtgtgcct attctacatt tagagcttat atccttaaac atgatgagtt taatcgttat
      121 tttatgaaag gttatcaaca gatgtcgcct aaaggcacaa cgagattcga gacaaaagcc
      181 ggtcatcaag cacagtttga ctggaaagaa ggtattaact ttaaaacgaa ggataatcaa
      241 atcgtttcac taaatatagg cgtactacta cttccttatt cccgttttgt aatcatgcaa
      301 gtgacaatga ataaatcaag tgatgtctta tttaatttat tgacacaagc gtttgagcta
      361 atgggaggtg tgcctaatga acttgtaacg gataacatga aaacggtcat ggatcaacca
      421 agaacagaac gtacaaatgg tcaaataaat cgcagattta aacaattcgc tgatgatttt
      481 aattttaaag taaaaccttg tattgccggc cgtcctagaa caaagggtaa agttgaatcg
      541 ataatgaaaa tattagatga aattcatgca ta
//
LOCUS       DAPSKH010000172          528 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPSKH010000172 DAPSKH010000000
VERSION     DAPSKH010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 528)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 528)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..528
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.180"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            103..309
                     /locus_tag="RPH49_002763"
     CDS             103..309
                     /locus_tag="RPH49_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125841.1"
                     /translation="MNEIETIISEIEKLLTNNTPYSISKNSGVPRQTVTDLKVGKTKI
                     KEAKFKTIIKLYEYQRTLENKTEC"
BASE COUNT          227 a           57 c           80 g          164 t
ORIGIN      
        1 gaattaacta gtttggcaac tagaaaaaaa caatgtattg ctaaacgtag ttactgcatt
       61 aggattatta taattataaa tagaaagaga gtgtgattaa taatgaatga gattgaaact
      121 attataagtg aaatagaaaa gttattaact aacaatacac catatagtat ttcaaaaaac
      181 tcaggtgtac cacgtcaaac agttactgat ttaaaggtag gtaaaactaa aataaaagaa
      241 gctaaattta aaacgataat caagttatat gaatatcaaa gaacattaga aaataaaaca
      301 gaatgttaac aaaaatattt tgttaggtta ggtggacaag aaattaaatt tctaatgatt
      361 tcatggttgt ctgtccacgt tttgtccacc tcaataagat aatctcttag ttttagaaat
      421 tgtacatggt taaataatca aaaatgcata ttatgaaatt atcattgcca ttaaatcttg
      481 aatgatcttt aagcgatgat ataaaaggct gaacacagta aataagtt
//
LOCUS       DAPSKH010000173          519 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPSKH010000173 DAPSKH010000000
VERSION     DAPSKH010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..519
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.181"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            46..519
                     /locus_tag="RPH49_002764"
     CDS             46..519
                     /locus_tag="RPH49_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDY5125842.1"
                     /translation="MVAYNKGEDIKEPLFISYDKYNEYSSISDKVENGDLLVTGVGTI
                     GVPFLIKDNTPLYFKDGNIIWLKNRGSLDEYFLFYSFINANIQSYIKKVAGVGTVGTY
                     TIANAKKTPIFEPIKLEQLKIGGFFNKIDNLIKLQVHKVEIIKQRKQGLLQKIFM"
BASE COUNT          210 a           59 c           91 g          159 t
ORIGIN      
        1 tcagactggc aatctagtgg agtacccttt ttaagagcaa gagacattgt ggcatataat
       61 aaaggggaag atattaaaga acccctattc atatcttatg ataaatataa tgaatatagc
      121 tcaatatcag ataaagttga aaatggcgat ttattagtaa cgggtgtggg cacaattgga
      181 gtaccatttt taataaaaga taatacgccg ctttacttta aagatggtaa tattatttgg
      241 ttaaagaata gagggagttt ggatgaatat tttctatttt attcttttat aaatgcaaat
      301 attcaaagct atataaaaaa agtggcaggt gtgggtactg ttggcacata cacaatagct
      361 aatgcaaaaa aaacaccaat ttttgaacca ataaaattag aacaattaaa aataggggga
      421 tttttcaata aaatcgataa tttaattaag ttacaagttc acaaagtaga aataattaaa
      481 caacgtaaac aagggttact tcagaaaata tttatgtaa
//
LOCUS       DAPSKH010000174          507 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPSKH010000174 DAPSKH010000000
VERSION     DAPSKH010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..507
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.182"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>507
                     /gene="sen"
                     /locus_tag="RPH49_002765"
     CDS             <1..>507
                     /gene="sen"
                     /locus_tag="RPH49_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="staphylococcal enterotoxin type N"
                     /protein_id="HDY5125843.1"
                     /translation="ESNKISTDQLLNNTIILKNIDISILKTSSLKVEFNSSDLANQFK
                     GKNIDIYGLYFGNKCVGLTEEKTSCLYGGVTIHDGNQLDEEKVIGINVFKDGVQQEGF
                     VIKTKKAKVTVQELDTKVRFKLENLYKIYNKDTGNIQKGCIFFHSHNHQDQSFYYDLY
                     NVKGSVGAE"
BASE COUNT          218 a           55 c           80 g          154 t
ORIGIN      
        1 gagtcaaata aaattagtac agatcaacta ctgaataata ctataatatt aaaaaatatt
       61 gatatatcca tacttaaaac ttctagtttg aaagttgagt ttaactcatc agatttagca
      121 aatcaattta aaggaaaaaa tatagatatt tatggactgt attttggaaa taaatgtgta
      181 ggcttaactg aagaaaaaac atcatgctta tacggaggag ttacgataca tgatggaaat
      241 caattagatg aagagaaagt tataggcatt aatgtattta aagatggtgt ccaacaagaa
      301 ggttttgtta taaaaaccaa aaaggctaaa gtaacagtac aagaattaga cactaaagtt
      361 cgatttaaat tagaaaattt atataaaata tacaataaag ataccggtaa catacaaaaa
      421 ggatgcattt tctttcattc tcataatcat caagatcaat cattttatta tgatttatat
      481 aacgtaaaag gttcagtggg agcagag
//
LOCUS       DAPSKH010000175          486 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.183, whole genome shotgun sequence.
ACCESSION   DAPSKH010000175 DAPSKH010000000
VERSION     DAPSKH010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.183"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            25..237
                     /locus_tag="RPH49_002766"
                     /pseudo
     CDS             25..237
                     /locus_tag="RPH49_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625397.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc peptidase"
BASE COUNT          194 a           54 c           71 g          167 t
ORIGIN      
        1 gtttaaagcg agaaagtatt atctttagac gacgtgattg aaatgtcacg tcctgtcaaa
       61 atgaatagtt tattaaagtt gtattttgat agaaatatac tgacaccaca aaaattattg
      121 aattatttaa aagttgatga aacatttttg aatcatctag caggtattaa tttaaaactc
      181 tttaaggatt atgttaatga aaatagagaa tataatataa cgaatctata taaataaggc
      241 accaatattt aaacctcgag ctgaaaagat catcatttca gttcgaggtt tttatttgta
      301 acatctgttg ataggcatcg acaaggacct tttaatgttg tgttttgtgc gatataacaa
      361 gctttttagg ctattaaaga atattcagaa ttaaatatat aattatgaat aaattatgtc
      421 attgaaaaaa ttatgattat aaaatcattc taaaaacacc gaaataacaa tgatttcatg
      481 aaaaca
//
LOCUS       DAPSKH010000176          477 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPSKH010000176 DAPSKH010000000
VERSION     DAPSKH010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..477
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.184"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..447
                     /locus_tag="RPH49_002767"
     CDS             <1..447
                     /locus_tag="RPH49_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001039417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HDY5125844.1"
                     /translation="ATLNESNNWSHTWTGLDEKAKGQQVKYTVEELTKVKGYTTHVDN
                     NDIGNLIVTNKYTPEKPNKPIYPEKPKDKTPPTKPDHSNKVKPTPPDKPSKVDKADQS
                     KDNKTKPENPLKELPKTGMKIITSWITWVFIGILGLYLILRKRFNS"
BASE COUNT          211 a           77 c           71 g          118 t
ORIGIN      
        1 gcaacattaa atgaatctaa taactggagc catacgtgga caggattaga tgaaaaagca
       61 aaaggtcaac aagtaaaata cacagtcgag gaattaacaa aggtcaaagg ttatacaaca
      121 catgtggata acaatgatat aggtaacttg attgtaacga ataaatatac gccagaaaaa
      181 ccgaataaac caatctatcc tgaaaaacca aaagacaaaa caccaccaac taaacctgat
      241 cattctaata aagttaaacc aactccccca gataagccat caaaagtgga taaggctgat
      301 caatctaaag ataataaaac caaacctgaa aatcctctaa aagaattacc aaaaactggt
      361 atgaagatta taacttcatg gattacatgg gtatttatag gtatattggg attgtattta
      421 attttaagaa aaagatttaa ctcataaacc attataatta tttttataga tatggct
//
LOCUS       DAPSKH010000177          452 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPSKH010000177 DAPSKH010000000
VERSION     DAPSKH010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.185"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>452
                     /locus_tag="RPH49_002768"
     CDS             <1..>452
                     /locus_tag="RPH49_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDY5125845.1"
                     /translation="EQKFYYKRILWQYLKDKHGLMCAYSTFRAYILKHDEFNRYFMKG
                     YQQMSPKGTPRFETKAGHQAQFDWKEGINFKTKDNQIVSLNIGVLLLPYSRFVIMQVT
                     MNKSSDVLFNLLTQAFELMGGVPNELVTDNMKTVMDQPRTERTNGQINR"
BASE COUNT          161 a           75 c           86 g          130 t
ORIGIN      
        1 gaacaaaagt tctactataa gcgtattctt tggcaatatt tgaaggataa acatgggtta
       61 atgtgtgcct attctacatt tagagcttat atccttaaac atgatgagtt taatcgttat
      121 tttatgaaag gttatcaaca gatgtcgcct aaaggcacac cgagattcga gacaaaagcc
      181 ggtcatcaag cacagtttga ctggaaagaa ggcattaact ttaaaacgaa ggataatcaa
      241 atcgtttcac taaatatagg cgtactacta cttccttatt cccgctttgt aatcatgcaa
      301 gtgacaatga ataaatcaag tgatgtctta tttaatttat tgacacaagc gtttgagcta
      361 atgggaggtg tgcctaatga acttgtaaca gataacatga aaacggtcat ggatcaacca
      421 agaacagaac gtacaaatgg tcaaataaat cg
//
LOCUS       DAPSKH010000178          409 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPSKH010000178 DAPSKH010000000
VERSION     DAPSKH010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..409
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.186"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            1..76
                     /locus_tag="RPH49_002769"
                     /pseudo
     CDS             1..76
                     /locus_tag="RPH49_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622381.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
BASE COUNT          173 a           45 c           72 g          119 t
ORIGIN      
        1 aagtaccaca gtgccacatg tcggcaattg gcgagacaag ttctttaaag agcgtgaagg
       61 taaatatcaa gtagaaggtt gttttattga atcaggtgca cttaataata aaagtgatga
      121 atacggtatc aaaaggaaca gacatgctca aatttattat aattcagtta gaaatcgaga
      181 taaacagata gagatttcta aaattgctaa aaatactaat ataaataaaa atttaattca
      241 aagagtttat gaacatatat ttgaaaataa gtatttatta gaaagtggat ttaaacaatt
      301 tgatcctgac ttttatatgg ctcaaagttg gcaacgttta agagaaggga aaaatattaa
      361 aaaaatggat ataataacgt agaaacatga agctcttgaa cactatcta
//
LOCUS       DAPSKH010000179          406 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPSKH010000179 DAPSKH010000000
VERSION     DAPSKH010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.187"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..225
                     /locus_tag="RPH49_002770"
     CDS             <1..225
                     /locus_tag="RPH49_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDY5125846.1"
                     /translation="EQCINKDLKLLDYRVQQILEGVLSESTTYGDARNKLETLKIIAE
                     SHFKTEHASVIYKLALKKLDEKINATPIKE"
     gene            245..382
                     /locus_tag="RPH49_002771"
     CDS             245..382
                     /locus_tag="RPH49_002771"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125847.1"
                     /translation="MFKVLNDIKTSLKNHPWGWKEHLPYLLMLTLSLVALILGVLSAI
                     L"
BASE COUNT          145 a           63 c           70 g          128 t
ORIGIN      
        1 gaacaatgca tcaataaaga cttaaaactt ttagattatc gagttcaaca aattttagaa
       61 ggtgttctat cagaaagtac cacatacggt gatgcaagaa ataaattaga aacattgaaa
      121 attattgctg aatctcattt taaaaccgaa catgcttcag ttatttacaa attagcattg
      181 aaaaagttag acgaaaaaat caacgccact ccaattaaag agtgacggaa agggaggatt
      241 ttaaatgttt aaggttttaa atgatataaa aacttcttta aaaaaccatc cttggggttg
      301 gaaagagcac ttaccttatt tgctgatgtt aactctgtca cttgtggctc tgattctcgg
      361 tgttctgtcc gcgattctat gataacaggc tttatataga ttcctt
//
LOCUS       DAPSKH010000180          405 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPSKH010000180 DAPSKH010000000
VERSION     DAPSKH010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.188"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>405
                     /locus_tag="RPH49_002772"
     CDS             <1..>405
                     /locus_tag="RPH49_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HDY5125848.1"
                     /translation="RELHQALEVKTPYKKWFERMSDYGFEENIDYVVTDIFVHNPLGG
                     RQNQTDHALTLDTAKEIAMIQRSEPGKRARQYFIQVEKAWNSPEMIMQRALKIANNTI
                     NQLETKIERDKPKIVFADAVATTKTSILVGELA"
BASE COUNT          159 a           75 c           75 g           96 t
ORIGIN      
        1 cgagaacttc atcaagcatt agaggttaag actccataca aaaaatggtt tgaaagaatg
       61 agtgattacg gatttgaaga aaatatcgat tatgtagtca cggacatttt tgtccataac
      121 ccactaggag gtcgtcagaa tcaaactgac cacgcactca cactagacac tgcaaaagaa
      181 atcgcaatga ttcaacgcag tgaacctggt aaacgtgcaa gacaatactt catccaagtt
      241 gaaaaagcat ggaacagccc agaaatgatt atgcaacgtg ctttaaaaat tgctaacaac
      301 acaatcaatc aattagaaac aaagattgaa cgtgataaac caaaaattgt atttgcagat
      361 gcagtagcta ctactaagac atcaatttta gttggagagt tagca
//
LOCUS       DAPSKH010000181          391 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPSKH010000181 DAPSKH010000000
VERSION     DAPSKH010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..391
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.189"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            119..>391
                     /locus_tag="RPH49_002773"
     CDS             119..>391
                     /locus_tag="RPH49_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125849.1"
                     /translation="MDIIAICIAIFSFLLTALKYYLDYMKDSLNIDVIPTRSFNYLVD
                     DKSSYNDITFINFTKFPISVIDVEFDIKNKVNEQKTFKPIRYKDKNY"
BASE COUNT          127 a           58 c           55 g          151 t
ORIGIN      
        1 ttttcttttt cttgtatgtt gaacatttcg ccgatgttcg attttgtttt taatgcttgc
       61 atattgttta tgctcctttc gtgtataatg ttgttatcaa cctaaggagg tgataagtat
      121 ggacataatc gcgatttgta tcgcaatttt tagtttctta ctgactgcac ttaaatatta
      181 tttagactat atgaaagatt ctcttaacat cgatgttata cctaccagaa gctttaatta
      241 cttggtcgat gacaaatcaa gttacaacga tataacattt attaatttca caaagtttcc
      301 catttctgtt attgacgttg aatttgatat taaaaataaa gtaaatgaac aaaaaacgtt
      361 caaacctata cgatataaag ataaaaacta c
//
LOCUS       DAPSKH010000182          389 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPSKH010000182 DAPSKH010000000
VERSION     DAPSKH010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 389)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 389)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..389
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.190"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..86
                     /locus_tag="RPH49_002774"
     CDS             <1..86
                     /locus_tag="RPH49_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pathogenicity island protein"
                     /protein_id="HDY5125850.1"
                     /translation="SREKHLELIMKWCAQELKNNFQLEKGE"
     gene            89..>389
                     /locus_tag="RPH49_002775"
     CDS             89..>389
                     /locus_tag="RPH49_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1474 family protein"
                     /protein_id="HDY5125851.1"
                     /translation="MNWEIKDLMCDIEVIKQKINDVATKHAWFVEDRFVKNELETKRE
                     HINFSASYLEHRIQNEHTVELLHVYLKEFGELIQKFHEIEKASSENFGEVSDDAQK"
BASE COUNT          167 a           41 c           73 g          108 t
ORIGIN      
        1 tcagtcgtga aaagcactta gaattgataa tgaaatggtg cgcacaagaa ttaaagaata
       61 attttcaatt agagaaagga gaataaaaat gaattgggaa attaaagatt taatgtgtga
      121 cattgaagtg ataaaacaaa aaattaatga tgtagctacc aaacatgctt ggtttgttga
      181 agatagattt gtaaaaaatg aattagaaac aaaacgggaa catattaatt tttctgctag
      241 ctatttagaa catcggatac aaaatgaaca tacagttgag ttattacatg tgtacttaaa
      301 agaattcggt gaacttatac aaaaatttca tgaaatagaa aaagcatcat ctgagaactt
      361 tggcgaggta tcagatgacg cacaaaaat
//
LOCUS       DAPSKH010000183          386 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPSKH010000183 DAPSKH010000000
VERSION     DAPSKH010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 386)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 386)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..386
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.191"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..100
                     /locus_tag="RPH49_002776"
     CDS             <1..100
                     /locus_tag="RPH49_002776"
                     /inference="COORDINATES: protein motif:HMM:NF012948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDY5125852.1"
                     /translation="ENSGSNNATLFGGLFAALGSLLLFGRRKKQNK"
BASE COUNT          168 a           49 c           48 g          121 t
ORIGIN      
        1 tgaaaatagc ggctcaaata acgcaacgtt atttggcgga ttattcgcag cattaggatc
       61 attattgtta ttcggtcgtc gtaaaaaaca aaataaataa tacagcttat accaggtccg
      121 tgaggcctgg ttttttattt caaaatttat gaaatgtatc ttatgtttga gattaaatag
      181 tgcaattttt taaaaaatat aacataaatc aacataaatt taattcatct ttacattaaa
      241 agtacaaacg aataagaaaa gcaattaaac acagtatcaa accatttaaa acaattgata
      301 taaaaaacaa acgaataatt aaaaattact agaattaatt tattcagacc aaagtgtaaa
      361 ataacagtct tagataaata aattta
//
LOCUS       DAPSKH010000184          366 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPSKH010000184 DAPSKH010000000
VERSION     DAPSKH010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..366
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.192"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
BASE COUNT          151 a           64 c           22 g          129 t
ORIGIN      
        1 taaatcaaac ctcacattct tattagattg caaattcaat agtcctacca gaattgaaat
       61 caaaacattc aaactatttt atcgttttaa cttcctcgac cattttcacc tccttataat
      121 ctatataaat tatgtttacc acacgattct ttacactcga aaaattaatt ttgttaagaa
      181 acatttagcc atgtaacttt gtaataaaaa cattttcaaa taaatgtacc aaaaactttc
      241 atgaaataaa gtatactttt caaatctatt aattttagaa tcataaaacc aaatgctata
      301 ttacaatata attatcacaa atcatcatat atgccaatta cacaatttaa tataaaaaat
      361 tgtcaa
//
LOCUS       DAPSKH010000185          359 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPSKH010000185 DAPSKH010000000
VERSION     DAPSKH010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..359
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.193"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
BASE COUNT          153 a           40 c           64 g          102 t
ORIGIN      
        1 cacttagagg gatgttaatc ataaaaaaag agattttgaa aaatataggc tattatactt
       61 tagaattaca aattataaat cttgccagtg gatatgggag ttcaacatgt cacttacccc
      121 aatttgtgga atgttaaata actataaaga ggaaaggaga aaaaatgata agaatggtta
      181 aagaaaaaga acgaatagca aaattaaatt tcgaatagct gtgacgagct taataattca
      241 agtacttaat tttatcaaat cgttctttta aaaaggtaaa gggcaaaaga cctttaccac
      301 attaaatagg gaggtggtat ttatgacaag agaattaagg aaaaaattaa ctctctatc
//
LOCUS       DAPSKH010000186          346 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.194, whole genome shotgun sequence.
ACCESSION   DAPSKH010000186 DAPSKH010000000
VERSION     DAPSKH010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..346
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.194"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
BASE COUNT          129 a           38 c           50 g          129 t
ORIGIN      
        1 ttgtgtttat aaaatgttta aagccgagat tgtcgtaatt taatacttcg caatctcggc
       61 ttttctactt atgatatagg taatggcata aattgtggct tgataggatg aaattaaatt
      121 gattagatta aaaatcctgg cgtattttag taatgaataa tatataaact ttaccaaatt
      181 aaagctttaa agtggcataa aagataatta tacattttta atgacatttt gattgaactt
      241 ttctattgac tgtacagctt atagttagta tgattaaaca cgctccttaa aaaagaacaa
      301 attaaataaa ctttgatttg aaagacagtc aattctaaat ttaatt
//
LOCUS       DAPSKH010000187          339 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPSKH010000187 DAPSKH010000000
VERSION     DAPSKH010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..339
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.195"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(90..>339)
                     /locus_tag="RPH49_002777"
     CDS             complement(90..>339)
                     /locus_tag="RPH49_002777"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125853.1"
                     /translation="IKEDGDSDLTIEEIDLIGSHLDKEIEDCAQIRKQTRKKELKDET
                     VDAHLFFRTFLRLRMYITFYTHLICKKCFDLYKSYLEK"
BASE COUNT          120 a           54 c           33 g          132 t
ORIGIN      
        1 atataactct catgaaaatt gattaaacta aattaattag ttagccttaa atttaacaaa
       61 ttaaatcaaa ccgaatgagg ctaaattggt tatttttcaa gatatgattt gtataaatca
      121 aaacatttct tacaaatcaa atgtgtataa aatgtgatat acattctcaa ccttaaaaaa
      181 gttctaaaaa aaagatgagc atctactgtc tcatctttca gttctttttt acgggtctgt
      241 tttctaattt gagcacaatc ttcgatttct ttatctaaat gactaccaat taaatctatt
      301 tcttctattg ttaaatcgct atctccatct tcttttatc
//
LOCUS       DAPSKH010000188          327 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.196, whole genome shotgun sequence.
ACCESSION   DAPSKH010000188 DAPSKH010000000
VERSION     DAPSKH010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..327
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.196"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            35..283
                     /locus_tag="RPH49_002778"
     CDS             35..283
                     /locus_tag="RPH49_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125854.1"
                     /translation="MLILKIKEINDKSVTYKYFPNNDENIKPGIIQMDIDSLEVINAE
                     KSSLEKNTRDNYFIHAIDRIYINASKGLFPESELVAWG"
BASE COUNT          137 a           29 c           51 g          110 t
ORIGIN      
        1 ttatagtatt ttaattaatt agaggtggaa atgattgcta atattaaaaa taaaagaaat
       61 taatgataaa agtgttacat ataaatattt tcctaataat gatgaaaata ttaagcctgg
      121 tattattcaa atggatatag atagtcttga agttatcaat gctgaaaaat ctagtttaga
      181 aaaaaataca agagataatt attttattca tgccatagac agaatataca taaatgctag
      241 taaagggcta tttcctgaat ctgaactcgt agcatgggga taaagaaagt ttactttaaa
      301 aattttaacc ttcaaatgtg aaggtta
//
LOCUS       DAPSKH010000189          320 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPSKH010000189 DAPSKH010000000
VERSION     DAPSKH010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.197"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(55..>320)
                     /locus_tag="RPH49_002779"
     rRNA            complement(55..>320)
                     /locus_tag="RPH49_002779"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT           79 a           83 c           71 g           87 t
ORIGIN      
        1 atatgtcacg ttattccgca tcttctgaag aagatgttcc gaatatatcc ttagaaagga
       61 ggtgatccag ccgcaccttc cgatacggct accttgttac gacttcaccc caatcatttg
      121 tcccaccttc gacggctagc tcctaaaagg ttactccacc ggcttcgggt gttacaaact
      181 ctcgtggtgt gacgggcggt gtgtacaaga cccgggaacg tattcaccgt agcatgctga
      241 tctacgatta ctagcgattc cagcttcatg tagtcgagtt gcagactaca atccgaactg
      301 agaacaactt tatgggattt
//
LOCUS       DAPSKH010000190          314 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPSKH010000190 DAPSKH010000000
VERSION     DAPSKH010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..314
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.198"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..>314
                     /locus_tag="RPH49_002780"
     CDS             <1..>314
                     /locus_tag="RPH49_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125855.1"
                     /translation="VGHSKVIFDNGKEINFSNATPIIFAQYLKIELKKRNIIVDINNY
                     FNSTVISFAHDKKYRYKDMYIEKYNEIIKVMSEEDLNEASVLEAKELAKKDMNYNFKI
                     SE"
BASE COUNT          133 a           24 c           53 g          104 t
ORIGIN      
        1 gttggacatt ctaaagttat atttgataac gggaaagaaa ttaatttttc taatgcaacg
       61 ccaattatct tcgcacaata tttgaaaatt gaattgaaaa agagaaatat aattgtagat
      121 attaataatt attttaatag cactgttatt tcatttgcgc atgataaaaa atatagatat
      181 aaggatatgt atattgaaaa atacaatgaa attattaaag tgatgagtga agaagattta
      241 aatgaggcat cggttttaga agctaaagag ttagccaaga aagacatgaa ttataatttt
      301 aaaattagtg agta
//
LOCUS       DAPSKH010000191          300 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.denovo.199, whole genome shotgun sequence.
ACCESSION   DAPSKH010000191 DAPSKH010000000
VERSION     DAPSKH010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.denovo.199"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            113..195
                     /locus_tag="RPH49_002781"
     tRNA            113..195
                     /locus_tag="RPH49_002781"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:146..148,aa:Leu,seq:gag)
     gene            217..290
                     /locus_tag="RPH49_002782"
     tRNA            217..290
                     /locus_tag="RPH49_002782"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:249..251,aa:Gly,seq:tcc)
BASE COUNT          100 a           55 c           61 g           84 t
ORIGIN      
        1 acacaaatta atttaatgta aaaaaacgat taaaagttat tgacaaatat ttttaaacat
       61 aatataataa ataacgttct aaaaaacgaa gatgttttaa atgcctatat ccgcggtcgt
      121 ggcggaatgg cagacgcgct aggttgaggg cctagtggga gaaatcccgt ggaggttcaa
      181 gtcctctcgg ccgcatcaaa attcttaatt aaataagcgg gtgtagttta atggcaaaac
      241 ctcagccttc caagctgatg ttgtgggttc gattcccatc acccgctcca tagataattt
//
LOCUS       DAPSKH010000192         7085 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.092, whole genome shotgun sequence.
ACCESSION   DAPSKH010000192 DAPSKH010000000
VERSION     DAPSKH010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 7085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7085
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.092"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..429
                     /locus_tag="RPH49_002783"
     CDS             <1..429
                     /locus_tag="RPH49_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrxA/BrxB family bacilliredoxin"
                     /protein_id="HDY5125856.1"
                     /translation="YDAYMKEIAQQMRGELTQNGFTSLETSEAVLEYMNQVNADDTTF
                     VVINSTCGCAAGLARPAAVAVATQNEHRPTNTVTVFAGQDKEATATMREFIQQVPSSP
                     SYALFKGQDLVYFMPREFIEGRDINDIAMDLKDAFDENCK"
     gene            853..1809
                     /locus_tag="RPH49_002784"
     CDS             853..1809
                     /locus_tag="RPH49_002784"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDY5125857.1"
                     /translation="MLNSFDAAYHSLCEEVLEIGNTRNDRTNTGAISKFGHQLRFDLS
                     KGFPLLTTKKVSFKLVATELLWFIKGDTNIQYLLKYNNNIWNEWAFENYIKSDEYKGP
                     DMTDFGHRALSDPEFNEQYKEQMKQFKQRILEDDTFAKQFGDLGNVYGKQWRDWVDKD
                     GNHFDQLKTVIEQIKHNPDSRRHIVSAWNPTEIDTMALPPCHTMFQFYVQDGKLSCQL
                     YQRSADIFLGVPYNIASYALLTHLIAKECGLEVGEFVHTFGDAHIYSNHIDAIQTQLA
                     RESFNPPTLKINSDKSIFDINYEDLEIVDYESHPAIKAPIAV"
     gene            2009..2488
                     /locus_tag="RPH49_002785"
     CDS             2009..2488
                     /locus_tag="RPH49_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDY5125858.1"
                     /translation="MTLSILVAHDLQRVIGFENQLPWHLPNDLKHVKKLSTGHTLVMG
                     RKTFESIGKPLPNRRNVVLTSDTSFNVEGVDVIHSIEDIYQLPGHVFIFGGQTLFEEM
                     IDKVDDMYITVIEGKFRGDTFFPPYTFEDWEVTSSVEGKLDEKNTIPHTFLHLIRKK"
     gene            2503..3342
                     /gene="fakB2"
                     /locus_tag="RPH49_002786"
     CDS             2503..3342
                     /gene="fakB2"
                     /locus_tag="RPH49_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid kinase binding subunit FakB2"
                     /protein_id="HDY5125859.1"
                     /translation="MTKQIIVTDSTSDLSKEYLEANNIHVIPLSLTIEGVSYVDQVDI
                     TSEEFINHIENDEDVKTSQPAIGEFISAYEELGKDGSEIISIHLSSGLSGTYNTAYQA
                     SQMVDANVTVIDSKSISFGLGYQIQHLVELVKEGVSTSEIVKKLNHLRENIKLFVVIG
                     QLNQLIKGGRISKTKGLIGNLMKIKPIGTLDDGRLELVHNARTQNSSIQYLKKEIAEF
                     IGDHEIKSVGVAHANVIEYVDKLKKVFNEAFHVNNYDINVTTPVISAHTGQGAIGLVV
                     LKK"
     gene            3428..3961
                     /gene="msrA"
                     /locus_tag="RPH49_002787"
     CDS             3428..3961
                     /gene="msrA"
                     /locus_tag="RPH49_002787"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDY5125860.1"
                     /translation="MTKEYATLAGGCFWCMVKPFTSYPGIKSVVSGYSGGHVDNPTYE
                     QVCTNQTGHVEAVQITFDPEVTSFENILDIYFKTFDPTDDQGQFFDRGESYQPVIFYH
                     DEHQKKAAEFKKQQLNEQGIFKKPVITPIKPYKNFYPAEDYHQDYYKKNPVHYYQYQR
                     GSGRKAFIESHWGNQNA"
     gene            3954..4382
                     /gene="msrB"
                     /locus_tag="RPH49_002788"
     CDS             3954..4382
                     /gene="msrB"
                     /locus_tag="RPH49_002788"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDY5125861.1"
                     /translation="MLKKDKSELTDIEYIVTQENGTEPPFMNEYWNHFAKGIYVDKIS
                     GKPLFTSEEKFHSECGWPSFSKALDDDEIIELVDKSFGMVRTEVRSEESNSHLGHVFN
                     DGPKESGGLRYCINSAAIQFIPYEKLEELGYGDLISHFDK"
     gene            4394..4894
                     /locus_tag="RPH49_002789"
     CDS             4394..4894
                     /locus_tag="RPH49_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDY5125862.1"
                     /translation="MFKKLFGKGKEVQKDIAIYAPLTGEYVKIEDIPDPVFAQKMMGE
                     GFGINPTEGEVVSPIAGRVDNVFPTKHAIGLKADNGLELLVHIGLDTVQLDGEGFEVL
                     VSSGDEVNVGDPLVRFNLEFINNNAKSVISPIIITNTDQAASINIYDENAVIKGETKV
                     IDVTMN"
     gene            4894..5115
                     /locus_tag="RPH49_002790"
     CDS             4894..5115
                     /locus_tag="RPH49_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDY5125863.1"
                     /translation="MKNYSFYQFVMTVRGRHDDKGRLAEEIFDDLAFPKHDDDFNILS
                     DYIETHGDFTLPMSVFDDLYEEYTEWLKF"
     gene            5304..6794
                     /locus_tag="RPH49_002791"
     CDS             5304..6794
                     /locus_tag="RPH49_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S41 family peptidase"
                     /protein_id="HDY5125864.1"
                     /translation="MDDKQHTSSSDDERAEIATSNQDQQTNSSKRVHLKRWQFISILI
                     GTILITAVITVVAYIFINQKISGLNKTDQANLNKIENVYKILNSDYYKKQDSDKLSKA
                     AIDGMVKELKDPYSEYLTKEQTKSFNEGVSGDFVGIGAEMQKKNDQIMVTSPMKGSPA
                     ERAGIRPKDVITKVNGKSIKGKALDEVVKDVRGKENTEVTLTVQRGSEEKDVKIKREK
                     IHVKSVEYKKKDKVGVITINKFQNDTSGELKDAVLKAHKDGLKKIVLDLRNNPGGLLD
                     EAVKMANIFIDKGKTVVKLEKGKDTEAIQTSNDSLKEAKDMDISILVNEGSASASEVF
                     TGALKDYNKAKVYGSKTFGKGVVQTTREFKDGSLLKYTEMKWLTPDGHYIHGKGIKPD
                     VTIDTPKYQSLNVIPNTKTFKVGDDDKNIKTIKIGLSALGYKVDNESTQFDQALENQV
                     KAFQQTNKLEVTGEFNKETNNKFTELLVEKANKHDDVLDKLINILK"
BASE COUNT         2650 a          997 c         1252 g         2186 t
ORIGIN      
        1 tatgatgctt atatgaaaga aattgcgcaa caaatgcgtg gcgaattaac tcaaaatggt
       61 tttacaagtt tagaaacgag cgaagcagta ttagagtata tgaaccaagt aaatgctgat
      121 gacacaactt ttgtagttat taactctaca tgcggctgtg cagctggatt agcaagacca
      181 gctgcagtag ctgttgcaac acaaaatgaa catagaccaa caaatacagt tacagttttt
      241 gcagggcaag ataaagaagc aactgctact atgcgagaat tcattcagca ggtaccatct
      301 agtccttcgt atgctttatt caaaggtcaa gatttagttt attttatgcc tagagaattt
      361 atcgaaggta gagatattaa tgacattgca atggacttaa aggatgcctt tgacgaaaat
      421 tgtaaatagt acacataaat aaatataaag gttaacacat tctataatat taaaaatggt
      481 gtctgtcatt gaaaatagag aatttagttg tattctattt gttatataaa gtccgtacac
      541 ttcaactata ttttctataa atttaactgt tttaatagga catcaaacat aatattcaaa
      601 tcatgtgtta acctcttttt taaaattttt tagcattaaa gttatagatt tgggtaaaca
      661 attagcaatt ggaaacattt atcactttac gatgtggtag gtacttaatc agcattttat
      721 aaattaagta acggaatcca tgatattaat atcacattcc taaaatgagt gataacaaaa
      781 tgctacataa agttaaatta tatcaaacta aatatacata ctataaataa tgaaaatgag
      841 gtgttatcgc atatgttgaa ttcatttgat gcagcatatc acagtctttg tgaagaagtt
      901 ttagaaatag gaaatacacg aaatgatcgc acaaatacag gtgcgatttc gaaatttggt
      961 catcaacttc gctttgactt atctaaagga tttccactat taacgacaaa gaaagtttct
     1021 tttaaattag tagcaaccga attattatgg ttcattaaag gagatacaaa catccaatac
     1081 ttattaaaat ataataataa tatttggaac gaatgggctt ttgaaaatta tattaaatca
     1141 gacgagtata aaggtccaga tatgacagat ttcggacatc gtgcattgag tgatcctgaa
     1201 tttaacgaac aatataaaga acaaatgaaa caatttaagc aacgtattct tgaagatgat
     1261 acatttgcga agcaattcgg tgatttagga aatgtttatg gtaaacaatg gcgagattgg
     1321 gttgataaag atggtaatca ttttgatcaa cttaaaacag taattgaaca aattaagcat
     1381 aatccagatt caagacgaca catcgtatct gcatggaatc caacagaaat tgatacaatg
     1441 gcacttccgc cttgtcatac aatgttccag ttttatgtcc aagatggtaa gttaagttgc
     1501 cagttatacc aacgtagcgc agatatcttt ttaggtgtgc catataatat cgcaagctac
     1561 gctttattga cacaccttat tgccaaagaa tgtggacttg aagtaggtga atttgtgcat
     1621 acatttggag atgcacatat ttattcaaat catattgatg caattcaaac tcaattagcg
     1681 cgtgaaagtt tcaatcctcc aacattaaaa attaacagtg acaagtctat tttcgacata
     1741 aattatgaag atttggaaat tgttgactat gaatcgcatc cagcaataaa agctccaata
     1801 gcagtgtagt cattgcatag ttagctaacc atatagacat caaaatgaca tcatagtatt
     1861 ttcaagtgca aaaaagtact tttttgtgtt aaacgttttc ataaattatg caaaatcatt
     1921 atttctatca cactttatga taaaaattgt gttaaattaa agataactta gtaataaaaa
     1981 atgaaatgat agaagaagga ggataattat gactttatcc attctagttg cacatgactt
     2041 gcaacgagta attggttttg aaaatcaatt accttggcac ctaccaaatg atttgaagca
     2101 tgttaaaaaa ctatcaacag gtcatacttt agtaatgggt cgtaagacat ttgaatcgat
     2161 tggtaaacca ctaccgaatc gtcgaaatgt tgtacttact tcagatacaa gtttcaacgt
     2221 agagggcgtt gatgtgattc attctattga agatatttac caactaccgg gacatgtttt
     2281 catatttgga gggcaaacat tatttgaaga aatgattgat aaagtggacg acatgtatat
     2341 tactgttatt gaaggtaaat tccgtggtga tacgttcttc ccaccttata catttgaaga
     2401 ctgggaagtt acctcttcag ttgaaggtaa actagatgag aaaaatacaa ttccacatac
     2461 ctttctacat ttaattcgta aaaaataagg gggaaaacga ccatgacaaa acagattata
     2521 gtaacagact caacatccga tttatctaaa gaatatttag aagcaaacaa cattcatgta
     2581 attcctttaa gtttaactat tgaaggagtt tcatacgttg accaagtaga tattacatca
     2641 gaagaattta ttaatcatat tgaaaatgat gaagatgtaa agacaagtca gccagccata
     2701 ggtgaattta tatctgctta tgaagaacta ggaaaagatg gctccgaaat cataagtatt
     2761 catctttctt caggattaag tggtacatat aacactgctt accaagcaag tcaaatggta
     2821 gatgctaatg taactgttat tgattcaaaa tctatttctt ttggtttagg gtatcaaata
     2881 caacacctag tagagcttgt aaaagaaggt gtctcaactt ctgaaatagt taaaaagtta
     2941 aatcatttaa gagaaaacat taaattattt gtagttatag ggcaattgaa tcaattaatt
     3001 aaaggtggca gaattagtaa aacaaaaggt ttgattggta atcttatgaa aatcaaacca
     3061 attggtacac tagatgatgg tcgcttagag cttgtgcaca atgcgagaac tcaaaattct
     3121 agtatccaat acttgaaaaa ggaaattgct gaatttatag gagatcatga aatcaaatcc
     3181 gttggtgtcg cacatgctaa cgttattgaa tatgttgata aattgaagaa agtttttaat
     3241 gaagcttttc atgtgaataa ttacgatata aatgtaacta caccagttat ttctgcacat
     3301 actggtcaag gtgcgattgg cctcgtagtc cttaagaagt aaatttaatc ttttcagtgt
     3361 taattacttc catttcaatc ctttatagac taaatttata attagataga tagaggaggt
     3421 aattcatatg acaaaagaat atgcaacatt agcaggagga tgtttctggt gcatggttaa
     3481 accatttaca tcatatccag gcatcaagtc agtcgtatct ggttatagtg gcggtcatgt
     3541 tgacaaccca acttatgaac aggtatgtac gaatcaaacc ggccatgtcg aagcagtaca
     3601 aattacgttt gatccagagg ttacttcctt tgaaaatata ttagacatat atttcaaaac
     3661 atttgaccca accgatgatc aagggcaatt tttcgataga ggcgaaagct atcaaccagt
     3721 cattttctat catgatgagc atcagaaaaa ggctgctgag tttaaaaagc aacaattaaa
     3781 tgaacaaggt attttcaaga aaccagtgat tacacctatt aaaccatata aaaatttcta
     3841 tccagctgaa gactaccatc aagattatta caaaaagaac ccggtacatt attaccaata
     3901 tcaacgtggt tcaggtagaa aagcgtttat agaatcacat tgggggaatc aaaatgctta
     3961 aaaaagataa aagcgaacta acagatatag aatatattgt tacacaagaa aatggtactg
     4021 aaccaccatt tatgaatgaa tattggaatc attttgctaa agggatttac gtagataaga
     4081 tttctggtaa acctttattt acatctgaag aaaagtttca ttctgagtgc ggatggccta
     4141 gcttttccaa agcgcttgat gacgatgaaa ttatagaatt agtcgacaaa tcatttggta
     4201 tggtaagaac tgaagtccgt tcagaagaat caaatagtca tttaggacac gtctttaatg
     4261 atggacctaa agaaagtggc ggcttaagat actgtatcaa ttccgctgca attcaattta
     4321 ttccatatga aaaattagaa gaattgggtt atggcgattt aatatcacat tttgataagt
     4381 aggagtggaa agtatgttta aaaaattatt cggaaaaggc aaagaagttc agaaagatat
     4441 cgcaatttat gcaccattaa ctggagaata cgtgaaaatt gaagatattc cagatcctgt
     4501 attcgcacaa aaaatgatgg gcgaaggttt tggtattaat ccaactgaag gagaagttgt
     4561 gtctccaatt gcaggacgtg ttgacaatgt ctttccaact aagcatgcga ttgggttaaa
     4621 agcagataac ggattagaat tattagttca tatcggttta gacacagttc aattagacgg
     4681 tgaaggattt gaagtgttag tgtctagtgg tgacgaagtt aacgtcggag atccattagt
     4741 aagattcaac cttgaattta ttaataataa cgctaaatct gttatttcac caattataat
     4801 tacaaacact gatcaagcag cttcaattaa tatttatgat gaaaatgctg tgattaaagg
     4861 tgaaacaaaa gtgattgatg tgacaatgaa ctaatgaaaa actattcgtt ttatcaattt
     4921 gtcatgacag ttcgtggtcg acacgacgat aaaggtcgtc tagcagaaga gatatttgac
     4981 gatcttgctt tcccaaaaca cgatgatgat tttaacatac tgtctgatta tattgagaca
     5041 catggtgatt tcacattgcc aatgtctgta tttgatgatt tatatgaaga atatacggaa
     5101 tggctaaaat tttaacataa tatttaataa tagttagaac cagggtgatg caatttgtta
     5161 tcctggtttt aatttaaaat aaactaagtt gtgactaaaa attaatcaat tatagtgaaa
     5221 tatggtgcgc tatcttgcat aaattgatat gattaactac acagaattta aaagtacata
     5281 atacataata aggaagtgat acaatggatg ataagcaaca cacatcttca tccgatgatg
     5341 aacgcgctga aattgcaaca agcaatcaag accaacaaac taattcatcg aaacgcgttc
     5401 acttaaaacg ttggcaattc atatcaattt taattggtac aatcctaata acagctgtca
     5461 tcacagttgt tgcatatatt tttataaatc aaaaaataag tggtttaaac aaaactgatc
     5521 aagcaaactt aaataaaatt gaaaatgtgt ataaaatctt aaatagtgat tattacaaaa
     5581 aacaggactc tgacaagtta agtaaagctg caattgatgg catggtcaaa gaattaaaag
     5641 atccttattc tgaatattta acaaaagaac aaacgaaatc ctttaatgaa ggtgtttcag
     5701 gtgattttgt aggtattggt gcagaaatgc aaaagaaaaa tgatcaaatt atggttacta
     5761 gtcctatgaa gggatctcca gcagaacgtg ctggcattcg tcctaaagat gtcattacta
     5821 aagtaaatgg aaaatcaatt aaaggtaaag cattagatga agttgtcaaa gatgttcgtg
     5881 gtaaagaaaa cactgaagta actttaactg ttcaacgagg cagtgaagaa aaagacgtta
     5941 agattaaacg tgaaaaaatt catgttaaaa gtgttgagta taagaaaaaa gataaggttg
     6001 gagttattac tattaataaa ttccagaatg atacatcagg tgaattgaaa gatgcagttc
     6061 ttaaagctca caaagatggt ttgaaaaaga ttgttttaga tttaagaaat aatcctggtg
     6121 gactactaga tgaagctgtt aaaatggcaa atatttttat cgataaagga aaaactgttg
     6181 ttaaactaga aaaaggtaaa gatactgaag caattcaaac ttctaatgac tcgttaaaag
     6241 aagcgaaaga catggatata tccatcttag tgaatgaagg ttcagctagc gcttctgaag
     6301 tatttactgg tgcgctaaag gactataata aagctaaagt ttatgggtca aaaacattcg
     6361 gtaaaggtgt cgtacaaact acaagagagt ttaaggacgg ttcattgtta aaatatactg
     6421 aaatgaaatg gttaacgcca gatggtcatt atattcacgg taaaggcatt aaaccagacg
     6481 ttactattga cacacctaaa tatcaatctt taaatgtcat tcctaatacg aaaacattta
     6541 aagttggaga cgatgataaa aatattaaaa ctattaaaat tggtttatca gctttaggtt
     6601 ataaagttga taatgaatca acgcaatttg atcaagcttt agaaaatcaa gttaaagctt
     6661 tccaacaaac gaataaactc gaggtaactg gtgaatttaa taaagaaacg aataataaat
     6721 ttactgagtt attagttgaa aaagctaata aacatgatga tgttctcgat aaattgatta
     6781 atattttaaa ataagtgata cacactgcta aaattgtttt attatgttaa tgacacgcct
     6841 cctaaatttg caaagatagc aatttaggag gcgtgtttat ttttattgac gtctaactct
     6901 aaaagatata aattagacat ttacaaatga tgtaaataac gcaatttcta tcatcgctgt
     6961 taacaattca tgctttaata tagtatgagc atatactttt taaatagtat tattcactag
     7021 ttttaacaat cgattaattg gtatatgata cttttattgg ttatttttat cccatagtgt
     7081 gataa
//
LOCUS       DAPSKH010000193         5375 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.099, whole genome shotgun sequence.
ACCESSION   DAPSKH010000193 DAPSKH010000000
VERSION     DAPSKH010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 5375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5375
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.099"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..1286
                     /locus_tag="RPH49_002792"
     CDS             <1..1286
                     /locus_tag="RPH49_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDY5125865.1"
                     /translation="IVIRKAESIHSPITFWYGKYIILIPSLYFKSINDKKLKYIILHE
                     YAHAKNRDTLHLIIFHIFSIAMSYNPLIQIVKRKMIHDNEVEADRFVLNNINKNEFKS
                     YAEAIMDSVLKTPFFNKNILSHSFNGKKSLLKRRLINIKEANLKKQSKLILIFVCIFT
                     FFIMIIQSQFLMGQSLTDYNYKKPLQSDYQILDESKNFGSNSGSFVMYSMKKDKYYIY
                     NEKESRKRYSPDSTYKIYLALFGLDRHIISDKNSRMLWNHNHYPFDSWNKDQDLNTAI
                     QNSVNWYFERISNQISKNYTYDQLKQLNYGNKNLGSYKAYWLEDSLKISNLEQVIVLK
                     NMMEQNNHFSKNEKKQLSSSLLIRKNENYALYGKTGTGIVNGKYNNGWFVGYVITNHD
                     KYYFSTHLSDEKASGENAKLINEKILKEMGVLNGQ"
     gene            1276..1656
                     /gene="blaI"
                     /locus_tag="RPH49_002793"
     CDS             1276..1656
                     /gene="blaI"
                     /locus_tag="RPH49_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillinase repressor BlaI"
                     /protein_id="HDY5125866.1"
                     /translation="MANKQVEITMAEWDVMNIIWNKKSVSANEIVVEIQKNKEVSDKT
                     IRTLITRLYKKEIIKRYKYNNIYFYSSIIKEDDIKMKTAKTFLNKLYGGDMKSLVLNF
                     AKNEELNNKEIEELQDILNDISKK"
     gene            complement(1708..1845)
                     /locus_tag="RPH49_002794"
     CDS             complement(1708..1845)
                     /locus_tag="RPH49_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001805627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125867.1"
                     /translation="MTSYEEETDYRNVPRELLDNNIPMGRGMIKWAAFIICTNLIKNL
                     I"
     gene            2115..3143
                     /locus_tag="RPH49_002795"
     CDS             2115..3143
                     /locus_tag="RPH49_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDY5125868.1"
                     /translation="MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLETGFELEASTYL
                     VRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFE
                     AVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAV
                     TDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAE
                     YNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQH
                     LELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERNKETGKITLCDNTRVA
                     SEGVCVIF"
     gene            complement(3263..4642)
                     /locus_tag="RPH49_002796"
     CDS             complement(3263..4642)
                     /locus_tag="RPH49_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDY5125869.1"
                     /translation="MNIIEQKFYDSKAFFNTQQTKDISFRKEQLKKLSKAIKSYESDI
                     LEALYTDLGKNKVEAYATEIGITLKSIKNARKELKNWTKTKNVDTPLYLFPTKSYIKK
                     EPYGTVLIIAPFNYPFQLVFEPLIGAIAAGNTAIIKPSELTPNVARVIKRLINETFDA
                     NYIEVIEGGIEETQTLIHLPFDYVFFTGSENVGKIVYQAASENLVPVTLEMGGKSPVI
                     VDETANIKVASERICFGKFTNAGQTCVAPDYILVHESVKDDLITALSKTLREFYGQNI
                     QQSPDYGRIVNLKHYHRLTSLLNSEQMNIVFGGHSDEDERYIEPTLLDHVTSDSAIMQ
                     EEIFGPILPILTYQSLDEAIAFIHQRPKPLSLYLFSEDENATQRVINELSFGGGAIND
                     TLMHLANPKLPFGGVGASGMGRYHGKYSFDTFTHEKSYIFKSTRLESGVHLPPYKGKF
                     KYIKAFFKN"
     gene            4694..4867
                     /locus_tag="RPH49_002797"
     CDS             4694..4867
                     /locus_tag="RPH49_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDY5125870.1"
                     /translation="MNVVAVNFKWSFELYMLKVENRAMNRLHNNIYNFNHNEKGRKKT
                     KIYTQHRKYFKKM"
     gene            complement(5062..>5375)
                     /locus_tag="RPH49_002798"
     CDS             complement(5062..>5375)
                     /locus_tag="RPH49_002798"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_500630.1"
                     /note="catalyzes the hydrolysis of pyrophosphate to
                     phosphate; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDY5125871.1"
                     /translation="FTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLF
                     VLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALT
                     K"
BASE COUNT         1967 a          719 c          871 g         1818 t
ORIGIN      
        1 atattgtgat tcgaaaagca gaatctattc attctccaat aactttttgg tatggaaaat
       61 atattatttt gattcccagt ttatatttta aaagtataaa tgacaaaaaa ctaaaatata
      121 taatattgca cgagtatgct catgctaaaa acagagatac tttgcattta attatctttc
      181 atattttttc tattgctatg agttataatc cactaataca aattgtaaaa agaaagatga
      241 ttcatgacaa tgaagtagaa gccgatagat ttgtccttaa taatattaac aaaaatgaat
      301 ttaagtctta tgcggaagct attatggatt ccgtattaaa aaccccattt ttcaacaaaa
      361 atatattaag ccattcattt aatggtaaaa aatcattact caaaagaaga ttaattaata
      421 taaaagaagc caatttgaaa aagcagtcaa aattaattct aatttttgtt tgtattttta
      481 ctttttttat catgataatt caaagccagt ttttaatggg gcaatcctta actgattata
      541 attataaaaa gcccttacaa agcgattacc aaattttaga tgaaagtaaa aattttggtt
      601 caaatagtgg atctttcgtt atgtacagca tgaagaaaga caaatactat atttataatg
      661 aaaaagaaag tagaaaaaga tattctcctg attcaacata caaaatttat ttagcactgt
      721 ttggacttga ccgtcatatt ataagtgata aaaattcacg tatgttatgg aatcataatc
      781 attatccttt cgattcttgg aataaggatc aagatttaaa tacggcaata caaaactctg
      841 ttaattggta cttcgaacgt attagtaatc aaatatcaaa gaactatact tatgatcaac
      901 tcaagcaatt aaattatggt aataaaaatt tgggaagtta taaagcctac tggttggaag
      961 atagtttgaa aatatctaat cttgaacaag taatagtttt gaaaaatatg atggaacaaa
     1021 ataaccattt tagtaaaaat gaaaagaaac aattatcttc ttcgttattg attagaaaaa
     1081 atgaaaatta tgcattgtat gggaaaacag gtacaggtat agtaaacggg aagtacaata
     1141 atgggtggtt tgtaggttac gtaattacaa atcatgataa gtattatttt tctacacatt
     1201 tatcagatga aaaagcctct ggtgaaaatg ctaaattaat aaatgaaaaa atattaaaag
     1261 aaatgggtgt tttaaatggc caataagcaa gttgaaataa ctatggctga atgggatgtt
     1321 atgaatataa tatggaataa aaaatcagta tcagctaatg aaattgtagt tgagattcaa
     1381 aaaaataaag aagttagcga taagacgatt agaacattaa ttacaagact atataaaaaa
     1441 gagattataa aacgatataa atataataat atttattttt actcatcaat tattaaagaa
     1501 gatgatatta aaatgaaaac tgctaaaacc tttcttaata aattgtatgg aggggatatg
     1561 aaaagtttag tgcttaattt tgcgaaaaat gaagaattaa ataacaaaga aattgaagaa
     1621 ttgcaagaca ttttaaatga tattagtaaa aaataaatag atatagggtt caaacataat
     1681 acatatataa attatgtttg aaccctatta aattagattt tttatgagat tagtacatat
     1741 aataaatgca gcccatttaa tcatgcctct tcccataggt atattgttat ctagtaattc
     1801 tcttggaacg ttacgataat cagtttcttc ttcataactt gtcatcctta attcacccca
     1861 atctgataat tacattatac gaacatgtgt tctattttgc aacaaaaatt ttgtggaagc
     1921 ataaacgcgt taataattaa tgctcgtgta agtaaaaaag agggattaat taaaatcgaa
     1981 taatgacata tcacagcaaa tagttctttt aaagtagtta aacagtttta gcgttaagga
     2041 aatgataaat gattgttaat tctagctaaa atttaataaa atgaaaataa gactgacatg
     2101 gaggggtaaa agtaatgaca aatggatata ttggttctta cactaaaaag aatggtaaag
     2161 ggatttatcg ttttgaatta aacgaaaatc agtcacgtat tgatttatta gaaacaggat
     2221 ttgaattaga agcgtctaca tatttggtgc gtaataacga agttttatat ggaatcaaca
     2281 aagaaggaga acaatgcggt gttgcgagtt tgaaaattga tgacaatggt gaattgcatt
     2341 tattaaataa atgtttgtct tcaaaagctg gtacaggttg ttatgtatcg atttcagaag
     2401 ataaacgata tttatttgaa gcggtatatg gtgctggcat catacgtatg tatgaattaa
     2461 atacgcacac aggtgaaatt atacgtctaa ttcaagaact tgcacatgat tttccaacag
     2521 gtacacatga aagacaagat catccacacg cacattatat taatcaaact ccagatggta
     2581 agtacgttgc agtaacagat ttaggtgctg atcgtatcgt tacttataaa tttgatgaca
     2641 acgggtttga attttataaa gaatctttat ttaaagatag tgatgggaca agacatattg
     2701 aatttcatga taatggaaaa tttgcttatg tcgtacacga attatcaaat actgtgagtg
     2761 ttgcagaata taatgacggt aaatttgaag agctcgagcg tcatttaaca attcctgaaa
     2821 actttgatgg agatactaaa cttgcagcag tgcgtttatc tcatgatcaa caattcttat
     2881 atgtatctaa tagagggcat gatagcattg caatttttaa agttcttgat aatggtcaac
     2941 acttagaact agtaacaatt actgaaagtg gtggtcaatt cccaagagat tttaatattg
     3001 cctcatcaga tgacctttta gtttgtgctc atgagcaagg agattcagtt gtaactgttt
     3061 tcgaaagaaa taaagaaaca ggtaaaatta cgctatgtga taacactcgt gtagcatctg
     3121 aaggtgtatg tgtcatattt taatctttaa ttaatcatga taaaaagaaa accatgtttc
     3181 caaaaaattt atgtatacct tgaaatttat tgttttcaag aacatcaaat tatggaagca
     3241 tggtttattt ttggctcaaa aattaatttt taaagaaagc tttgatgtat ttaaatttac
     3301 ctttatatgg tggtaaatgg acacctgatt ctaatcgtgt agatttgaaa atgtagcttt
     3361 tttcatgtgt aaaagtgtcg aatgaatatt taccatgata gcgtcccata cctgaggcgc
     3421 caacaccacc aaatggtaat ttaggattcg ctaggtgcat caatgtatca ttaatagcgc
     3481 cgccgccaaa tgatagctcg tttattacac gttgtgtagc attttcatct tcgctaaata
     3541 aatataaact caaaggtttt ggtctttggt gaataaaggc tattgcttca tccaatgact
     3601 gatacgttaa aatcggtaag ataggaccaa aaatttcttc ttgcataatt gctgaatcac
     3661 ttgtaacgtg atctaacaat gttggttcta tataacgttc atcctcatca ctatgaccac
     3721 caaatacaat attcatttgt tcactgttaa gtaatgaagt cagacgatga taatgtttaa
     3781 ggtttacaat gcggccataa tctggacttt gttgtatatt ttgaccataa aattcacgca
     3841 acgtttttga tagggctgtg attaaatcat cttttacaga ttcgtgtact aaaatgtaat
     3901 ctggtgcaac acatgtttgg ccggcattag tgaatttccc aaaacaaatg cgctcactag
     3961 caactttaat attcgctgtt tcatcaacga tgactggaga tttaccgccc atttctaatg
     4021 tcacaggaac taaattttcg ctggcagctt gataaacgat tttgcctaca ttttcacttc
     4081 ctgtaaagaa gacatagtca aaaggtaagt gaattaacgt ttgcgtttct tcaattcctc
     4141 cctcaataac ttcaatgtaa tttgcatcaa atgtttcatt gattaatcgt ttaatcactc
     4201 gtgcaacatt tggtgtcaac tcagatggtt taataattgc cgtattacct gctgcaatag
     4261 caccgattaa aggttcgaac actagttgaa aaggatagtt aaatggtgca atgatcaaaa
     4321 ctgttccata aggttctttt ttgatatagc tttttgttgg aaataaatat aaaggtgtgt
     4381 ctacattttt tgttttagtc cagtttttaa gttccttacg ggcatttttg atacttttca
     4441 aagttatgcc aatttcagta gcataagctt cgactttatt ttttcctaaa tctgtatata
     4501 gtgcttctaa aatatcgctc tcgtatgatt taatagcttt gcttaacttc tttaattgct
     4561 cttttctaaa actaatatct ttagtttgtt gtgtattgaa aaaagcttta ctgtcataaa
     4621 atttttgctc aataatattc ataatgaaaa gaacctcctt atatgattat tttggaaaaa
     4681 gtgattaatt gatttgaatg ttgtggccgt taattttaaa tggtctttcg aattatatat
     4741 gttgaaagtt gaaaatagag cgatgaatcg tttacataat aatatttata actttaatca
     4801 taacgaaaaa ggtaggaaga aaacaaaaat ttatactcaa catcgcaaat attttaagaa
     4861 aatgtaaaga caaaagggga attgtataga aatcactaat ctgtgggtta gggtagctaa
     4921 aggaatgaaa actactattg aaaaggggtt gtaaattagt caaacgtaaa taaaaaacag
     4981 ttcattgaaa gtgaaataaa ttctacttta atgaactgtt agttaaatac aacatgtcta
     5041 tgattagaca gtaatatagt attattttgt taatgcttca gtgatttgag gtacgatttg
     5101 tttttttcga gaaacaacac cagataagaa ggccatgtca tcttctaatt gaacattgaa
     5161 tgcttcgccg actttatctt tttcagcacc tacaactaaa attttagaat cactattaat
     5221 gatgtcagta acaacaagta caaataagtc atatttttct tgtgcactta cagctaacat
     5281 ttctttttct aaatcttctt tacgatttaa cacttcgtca aggtcaacag cattaacttg
     5341 tgcaatacga gtcacatagt cacccatagt aaatg
//
LOCUS       DAPSKH010000194         4306 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.105, whole genome shotgun sequence.
ACCESSION   DAPSKH010000194 DAPSKH010000000
VERSION     DAPSKH010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 4306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4306
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.105"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            155..754
                     /locus_tag="RPH49_002799"
     CDS             155..754
                     /locus_tag="RPH49_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDY5125872.1"
                     /translation="MAFKLPNLPYAYDALEPYIDQRTMEFHHDKHHNTYVTKLNATVE
                     GTELEHQSLADMIANLDKVPEAMRMSVRNNGGGHFNHSLFWEILSPNSEEKGGVIDDI
                     KAQWGTLDEFKNEFANKATTLFGSGWTWLVVNDGKLEIVTTPNQDNPLTEGKTPILLF
                     DVWEHAYYLKYQNKRPDYMTAFWNIVNWKKVDELYQAAK"
     gene            complement(1097..1852)
                     /locus_tag="RPH49_002800"
     CDS             complement(1097..1852)
                     /locus_tag="RPH49_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDY5125873.1"
                     /translation="MEVVYVTQTQPKFLTIYNTLYKEIQIGKYPSGHALPTEKELCAR
                     FDVSRMTLRQAIKLLAEDGIVESTRGKGHFVIPQTNAQHASSMDQFKHPLDQILLDRV
                     SMSSINYRVDLESEYTNHLFANHPSAVIAMERYYQKKDNHSKQADAFCFTFIPLNVID
                     TFKVNTQNEDDMKTFVEQTIYSNAYQSDLKMSITKAPHFKNHSHVFDGDTHCWLIIET
                     LYAQTPYPIMINKWYIPQEISELTLTRIRQSDY"
     gene            2088..2795
                     /gene="deoD"
                     /locus_tag="RPH49_002801"
     CDS             2088..2795
                     /gene="deoD"
                     /locus_tag="RPH49_002801"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDY5125874.1"
                     /translation="MKSTPHIKPMNDVEIAETVLLPGDPLRAKFIAETYLDDVEQFNT
                     VRNMFGFTGTYKGKKVSVMGSGMGMPSIGIYSYELIHTFGCKKLIRVGSCGAMQENID
                     LYDVIIAQGASTDSNYVQQYQLPGHFAPIASYQLLEKAVETARDKGVRHHVGNVLSSD
                     IFYNADTTASERWMRMGILGVEMESAALYMNAIYAGVEALGVFTVSDHLIHETSTTPE
                     ERERAFTDMIEIALSLV"
     gene            2802..4154
                     /gene="tet(38)"
                     /locus_tag="RPH49_002802"
     CDS             2802..4154
                     /gene="tet(38)"
                     /locus_tag="RPH49_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001100300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(38)"
                     /protein_id="HDY5125875.1"
                     /translation="MNVEYSKIKKAVPILLFLFVFSLVIDNSFKLISVAIADDLNISV
                     TTVSWQATLAGLVIGIGAVVYASLSDAISIRTLFIYGVILIIIGSIIGYIFQHQFALL
                     LVGRIIQTAGLAAAETLYVIYVAKYLSKEDQKTYLGLSTSSYSLSLVIGTLSGGFIST
                     YLHWTNMFLIALIVVFTLPFLFKLLPKENNTNKAHLDFVGLILVATIATTVMLFITNF
                     NWLYMIGALIAIIVFALYIKNAQRPLVNKSFFQNKRYASFLFIVFVMYAIQLGYIFTF
                     PFIMEQIYHLQLDTTSLLLVPGYIVAVIVGALSGKIGEYLNSKQAIITAIILIALSLI
                     LPAFAVGNHISIFVISMIFFAGSFALMYAPLLNEAIKTIDLNMTGVAIGFYNLIINVA
                     VSVGIAIAAALIDFKALNFPGNDALSSHFGIILIILGLMSIVGLVLFVILNRWTQSEK
                     "
     gene            4235..>4306
                     /locus_tag="RPH49_002803"
     CDS             4235..>4306
                     /locus_tag="RPH49_002803"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_498700.1"
                     /note="catalyzes the formation of D-glyceraldehyde
                     3-phosphate and acetaldehyde from
                     2-deoxy-D-ribose-5-phosphate; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-deoxyribose-5-phosphate aldolase"
                     /protein_id="HDY5125876.1"
                     /translation="MKFEKYIDHTLLKPESTRTQIDQI"
BASE COUNT         1439 a          650 c          756 g         1461 t
ORIGIN      
        1 ttaaatgcct ttttgcattc aatattaaat attatatcaa ttccgaatat ttaaatttta
       61 tataattgga tataacaaat aaataataat tattgcaaaa cacacccgaa attaattatt
      121 ataaaagtat attcataaaa ggaggaatat acttatggca tttaaattac caaatttacc
      181 atatgcatat gatgcattgg aaccatatat agatcaaaga acaatggagt ttcatcacga
      241 caaacatcac aatacgtacg tgacgaaatt aaacgcaaca gttgaaggaa cagagttaga
      301 gcatcaatca ctagcggata tgattgctaa cttagacaag gtaccggaag cgatgaggat
      361 gtcagtccgt aataatggcg gtggtcattt taaccattca ttattctggg aaatactatc
      421 acctaattct gaagaaaaag gtggcgtaat agacgacatt aaagcgcagt ggggcacttt
      481 agatgaattt aaaaatgaat ttgcaaataa agcaacaaca ttatttggat caggttggac
      541 ttggttagtt gttaatgatg gaaaattaga aattgtgaca acgccaaacc aagataatcc
      601 attaacagaa ggcaaaacac caatcttact atttgatgtt tgggagcatg cctactatct
      661 gaaatatcaa aataaacgtc cagactatat gactgcattt tggaatattg ttaactggaa
      721 aaaagttgat gaattatacc aagcagcaaa ataatataac ttaatataat tgaggtggag
      781 catctacaag gtgtttcacc ttttttgtat gtatgaggta atcaatttgc tttttgtata
      841 atgggttgga gaatcaaatg taggtaaaac agtacaatca tttacaatga tgaatacttt
      901 acttgtgttc tctgtgcttg tgaactcaat gtttcgagaa gagcgcacat cgaataacaa
      961 aattatttag acaacgttca acaaataaat aaacatcata cgttttaaag tagaaaaaat
     1021 catgtgatta cctgaaagtt attgtcgatt aaacaatagc taaacagtca tcacatgatt
     1081 ttttatttta ataattttaa taatccgatt gtcttatacg tgtcagtgtt aattcagata
     1141 tttcctgtgg aatataccac ttattaatca taattggata aggtgtttgt gcgtacaatg
     1201 tttcaataat cagccaacaa tgtgtatcac catcaaacac gtgactatga tttttgaagt
     1261 ggggcgcttt ggtaatagac atttttaaat ctgattgata tgcattgcta taaatcgtct
     1321 gctcaacgaa cgtcttcatg tcgtcttcgt tttgtgtatt cactttaaat gtgtcaatga
     1381 catttaacgg tataaaggta aaacaaaatg catcagcttg cttagaatga ttgtcctttt
     1441 tttgataata gcgttccatt gcaatgacgg cagaaggatg gtttgcaaac aaatgatttg
     1501 tatattcact ttctaaatca acacgataat taattgatga catagataca cgatctagca
     1561 atatttgatc aagtggatgc ttaaattgat ccatacttga agcgtgttgg gcatttgttt
     1621 gtggaataac gaagtgtccc ttccctcttg tactctctac gatgccatct tcggccaaca
     1681 attttatagc ttggcgcaaa gtcatacgac tgacatcaaa gcgcgcacaa agttcctttt
     1741 cagtaggtaa tgcatggcca ctcggatatt ttcctatttg aatttcttta tataacgtat
     1801 tataaatcgt taaaaatttt ggttgtgttt gcgtcacgta gacaacctcc ataaagttac
     1861 ttaatcactc tcatcataca ataattttta ctcgaattgg aaaaattata aaaattaaac
     1921 atagataggc tttgaaaatt agttttatac aaggttagaa gctataactg taaaatgttc
     1981 ttaatattgt caaaatgtaa tgcttgaaag cgcttttaaa aaatattatt atatacatgg
     2041 ttagacaaat agacaaatca ctatacaaat attgggagga atattttatg aaatcaacac
     2101 cacacattaa gccaatgaat gacgtcgaaa ttgcagaaac ggtgctattg ccaggagatc
     2161 cgttaagagc taagttcatt gcagaaacat atttggacga tgtggaacag ttcaatacag
     2221 tgcgaaacat gtttggtttt accggaacat ataaaggtaa aaaagtttct gtcatgggtt
     2281 caggtatggg tatgccatct attggcattt actcttatga attaattcat acatttggtt
     2341 gtaaaaaatt aattcgcgtt ggttcttgtg gcgcgatgca agaaaacatt gatttatatg
     2401 atgtgattat tgcacaaggt gcctctactg attcaaatta cgttcaacaa tatcaattac
     2461 caggtcattt tgcgccaatt gcttcttatc agttattaga aaaagcagtt gaaacagcac
     2521 gtgacaaagg tgtacgtcat catgtaggta atgtgttatc aagtgatatt ttctataacg
     2581 cggatacaac agcgagtgaa cgttggatgc gtatgggtat tttaggtgta gaaatggaat
     2641 cagctgcatt atacatgaat gcaatttacg ctggtgtcga agcattaggt gtgttcacag
     2701 tgagcgatca tttaattcat gaaacgtcaa caacacctga ggaaagggaa cgtgcattta
     2761 cagatatgat tgaaattgca ctgtcattgg tgtagatgat tatgaatgtt gaatattcta
     2821 aaataaagaa agcagtacct attttattat tcttatttgt attcagtttg gttatagaca
     2881 actcattcaa attgatttct gtagccattg ctgatgactt aaacatttct gtaactacag
     2941 taagttggca agcgacatta gccggtttag taattggtat tggcgctgta gtatacgctt
     3001 cattatctga tgccattagt atacgcacac tatttattta tggcgtgata ttaatcatta
     3061 tcggatcaat tattggttac attttccaac atcaattcgc attactttta gttggacgta
     3121 ttattcaaac tgcaggttta gctgctgcag agacattata tgtgatatat gttgcaaagt
     3181 atctttctaa agaggaccag aagacttacc ttggcttaag tacgagcagt tattccttgt
     3241 cattagttat cggtacatta tcaggtggat ttatttctac gtatttacac tggacaaata
     3301 tgtttttaat tgcattaatc gtagtattta cgttgccatt cctatttaaa ttattaccaa
     3361 aagaaaataa tacaaataaa gctcatttag attttgttgg cttaattcta gtggcaacta
     3421 ttgctacaac agtcatgctg tttattacga actttaattg gttatatatg attggtgctt
     3481 taattgcgat tatcgttttt gcgctatata ttaaaaatgc gcaacgtcca ttagtaaaca
     3541 aatcattttt ccaaaataaa cgttatgctt catttttatt tatagtattc gtaatgtatg
     3601 ctatccaatt gggttatatt tttacgttcc cattcataat ggaacaaatt tatcatcttc
     3661 aactagacac aacatcactg ttattagtac cgggttatat tgtagcagtc atcgttggtg
     3721 cactaagtgg taaaatcggc gaatatctta attcaaaaca agcgattatc acagcaatta
     3781 ttttaatcgc actgagctta attttacctg catttgcagt aggtaatcac atttcaatct
     3841 tcgtcatttc tatgatattc tttgcaggta gctttgcttt aatgtatgca cctttactta
     3901 acgaagccat taaaacaata gatcttaata tgacaggtgt ggctattggt ttttataatt
     3961 taattattaa tgtggcggta tctgtaggta ttgcgattgc tgcggctcta atcgatttta
     4021 aagcattaaa tttcccaggc aatgatgcat taagttcaca tttcggtatt attttaatta
     4081 ttttaggttt aatgagtatt gtcggattag ttttattcgt catcttaaat cgttggacac
     4141 aatctgaaaa ataaatagat ataaattcgc gagatatatt cgtatttata gtaaaattaa
     4201 ataaagagat tatataacac gaggagtagt aagtatgaaa tttgagaaat atatagatca
     4261 cactttattg aagcctgagt caacacgtac gcaaatcgat caaatc
//
LOCUS       DAPSKH010000195         3794 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.110, whole genome shotgun sequence.
ACCESSION   DAPSKH010000195 DAPSKH010000000
VERSION     DAPSKH010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 3794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3794
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.110"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            20..2029
                     /gene="mecA"
                     /locus_tag="RPH49_002804"
     CDS             20..2029
                     /gene="mecA"
                     /locus_tag="RPH49_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001801873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP2a family beta-lactam-resistant peptidoglycan
                     transpeptidase MecA"
                     /protein_id="HDY5125877.1"
                     /translation="MMKKIKIVPLILIVVVVGFGIYFYASKDKEINNTIDAIEDKNFK
                     QVYKDSSYISKSDNGEVEMTERPIKIYNSLGVKDINIQDRKIKKVSKNKKRVDAQYKI
                     KTNYGNIDRNVQFNFVKEDGMWKLDWDHSVIIPGMQKDQSIHIENLKSERGKILDRNN
                     VELANTGTAYEIGIVPKNVSKKDYKAIAKELSISEDYIKQQMDQNWVQDDTFVPLKTV
                     KKMDEYLSDFAKKFHLTTNETESRNYPLGKATSHLLGYVGPINSEELKQKEYKGYKDD
                     AVIGKKGLEKLYDKKLQHEDGYRVTIVDDNSNTIAHTLIEKKKKDGKDIQLTIDAKVQ
                     KSIYNNMKNDYGSGTAIHPQTGELLALVSTPSYDVYPFMYGMSNEEYNKLTEDKKEPL
                     LNKFQITTSPGSTQKILTAMIGLNNKTLDDKTSYKIDGKGWQKDKSWGGYNVTRYEVV
                     NGNIDLKQAIESSDNIFFARVALELGSKKFEKGMKKLGVGEDIPSDYPFYNAQISNKN
                     LDNEILLADSGYGQGEILINPVQILSIYSALENNGNINAPHLLKDTKNKVWKKNIISK
                     ENINLLTDGMQQVVNKTHKEDIYRSYANLIGKSGTAELKMKQGETGRQIGWFISYDKD
                     NPNMMMAINVKDVQDKGMASYNAKISGKVYDELYENGNKKYDIDE"
     gene            complement(2075..2503)
                     /locus_tag="RPH49_002805"
     CDS             complement(2075..2503)
                     /locus_tag="RPH49_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MaoC family dehydratase"
                     /protein_id="HDY5125878.1"
                     /translation="MKYDDFIVGETFKTKSLHITEEEIIQFATTFDPQYMHIDKEKAE
                     QSRFKGIIASGMHTLSISFKLWVEEGKYGEEVVAGTQMNNVKFIKPVYPGNTLYVIAE
                     ITNKKSIKKENGLVTVSLSTYNENEEIVFKGEVTALINNS"
     gene            complement(2600..3343)
                     /locus_tag="RPH49_002806"
     CDS             complement(2600..3343)
                     /locus_tag="RPH49_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphoryl diester phosphodiesterase"
                     /protein_id="HDY5125879.1"
                     /translation="MLTVYGHRGLPSKAPENTIASFKAASEVEGINWLELDVAITKDE
                     QLIIIHDDYLERTTNMSGEITELNYDEIKDASAGSWFGEKFKDEHLPTFDDVVKIANE
                     YNMNLNVELKGITGPNGLALSKSMVKQVEEQLTNLNQNQEVLISSFNVVLVKLAEEIM
                     PQYNRAVIFHTTSFREDWRTLLDYCNAKIVNTEDAKLTKAKVKMVKEAGYELNVWTVN
                     KPARANQLANWGVDGIFTDNADKMVHLSQ"
BASE COUNT         1356 a          606 c          576 g         1256 t
ORIGIN      
        1 gtcttatata aggagtatat tgatgaaaaa gataaaaatt gttccactta ttttaatagt
       61 tgtagttgtc gggtttggta tatattttta tgcttcaaaa gataaagaaa ttaataatac
      121 tattgatgca attgaagata aaaatttcaa acaagtttat aaagatagca gttatatttc
      181 taaaagcgat aatggtgaag tagaaatgac tgaacgtccg ataaaaatat ataatagttt
      241 aggcgttaaa gatataaaca ttcaggatcg taaaataaaa aaagtatcta aaaataaaaa
      301 acgagtagat gctcaatata aaattaaaac aaactacggt aacattgatc gcaacgttca
      361 atttaatttt gttaaagaag atggtatgtg gaagttagat tgggatcata gcgtcattat
      421 tccaggaatg cagaaagacc aaagcataca tattgaaaat ttaaaatcag aacgtggtaa
      481 aattttagac cgaaacaatg tggaattggc caatacagga acagcatatg agataggcat
      541 cgttccaaag aatgtatcta aaaaagatta taaagcaatc gctaaagaac taagtatttc
      601 tgaagactat atcaaacaac aaatggatca aaattgggta caagatgata ccttcgttcc
      661 acttaaaacc gttaaaaaaa tggatgaata tttaagtgat ttcgcaaaaa aatttcatct
      721 tacaactaat gaaacagaaa gtcgtaacta tcctctagga aaagcgactt cacatctatt
      781 aggttatgtt ggtcccatta actctgaaga attaaaacaa aaagaatata aaggctataa
      841 agatgatgca gttattggta aaaagggact cgaaaaactt tacgataaaa agctccaaca
      901 tgaagatggc tatcgtgtca caatcgttga cgataatagc aatacaatcg cacatacatt
      961 aatagagaaa aagaaaaaag atggcaaaga tattcaacta actattgatg ctaaagttca
     1021 aaagagtatt tataacaaca tgaaaaatga ttatggctca ggtactgcta tccaccctca
     1081 aacaggtgaa ttattagcac ttgtaagcac accttcatat gacgtctatc catttatgta
     1141 tggcatgagt aacgaagaat ataataaatt aaccgaagat aaaaaagaac ctctgctcaa
     1201 caagttccag attacaactt caccaggttc aactcaaaaa atattaacag caatgattgg
     1261 gttaaataac aaaacattag acgataaaac aagttataaa atcgatggta aaggttggca
     1321 aaaagataaa tcttggggtg gttacaacgt tacaagatat gaagtggtaa atggtaatat
     1381 cgacttaaaa caagcaatag aatcatcaga taacattttc tttgctagag tagcactcga
     1441 attaggcagt aagaaatttg aaaaaggcat gaaaaaacta ggtgttggtg aagatatacc
     1501 aagtgattat ccattttata atgctcaaat ttcaaacaaa aatttagata atgaaatatt
     1561 attagctgat tcaggttacg gacaaggtga aatactgatt aacccagtac agatcctttc
     1621 aatctatagc gcattagaaa ataatggcaa tattaacgca cctcacttat taaaagacac
     1681 gaaaaacaaa gtttggaaga aaaatattat ttccaaagaa aatatcaatc tattaactga
     1741 tggtatgcaa caagtcgtaa ataaaacaca taaagaagat atttatagat cttatgcaaa
     1801 cttaattggc aaatccggta ctgcagaact caaaatgaaa caaggagaaa ctggcagaca
     1861 aattgggtgg tttatatcat atgataaaga taatccaaac atgatgatgg ctattaatgt
     1921 taaagatgta caagataaag gaatggctag ctacaatgcc aaaatctcag gtaaagtgta
     1981 tgatgagcta tatgagaacg gtaataaaaa atacgatata gatgaataac aaaacagtga
     2041 agcaatccgt aacgatggtt gcttcactgt tttattatga attattaata agtgctgtta
     2101 cttctccctt aaatacaatt tcttcatttt cattgtatgt tgaaagtgac actgtaacga
     2161 gtccattttc tttttttatg gatttcttat ttgtaatttc agcgataacg tacaatgtat
     2221 tacctgggta tacaggttta ataaatttaa cgttattcat ttgtgttcct gctacaactt
     2281 cttctccgta tttaccttct tctacccata atttaaatga tattgaaagt gtatgcatgc
     2341 cagatgcaat gataccttta aatctacttt gttctgcttt ttctttatct atatgcatat
     2401 attgaggatc aaaagttgtt gcaaattgga taatttcttc ttctgtaata tgaaggcttt
     2461 ttgttttgaa tgtttctcct actataaaat catcgtattt catatatgtc tctctttctt
     2521 attcaaatta attttttagt atgtaacatg ttaaaggtaa gtctaccgtc actgaaacgt
     2581 aagactcacc tctaactttc tattgagaca aatgcaccat tttatctgca ttgtctgtaa
     2641 agataccatc aactccccaa ttagcaagtt ggtttgcacg tgctggtttg tttacagtcc
     2701 atacgttcaa ttcataaccc gcttctttta ccatttttac ttttgcttta gtaagtttgg
     2761 catcttcagt gtttactatt ttagcattac agtaatctaa aagtgttctc cagtcttcac
     2821 gaaacgaagt tgtatggaat ataactgctc tgttatattg tggcatgatt tcttctgcaa
     2881 gtttaacaag cacaacatta aagcttgaaa tgagcacttc ttgattctga tttaagtttg
     2941 ttaattgttc ttccacttgc ttaaccatac ttttagaaag tgctagtcca ttcggtccag
     3001 taataccttt taattctaca tttaaattca tattatattc atttgctatt tttactacat
     3061 catcgaaagt tggcaaatgt tcatctttga atttttcacc aaaccaagat cctgcagaag
     3121 catctttaat ttcatcataa ttcaattcag ttatttcccc ggacatattt gtagtccgtt
     3181 ctaaataatc atcatgaatg ataatcagtt gttcatcttt tgtaattgca acatctaact
     3241 ccaaccagtt tataccttct acttctgaag cagctttaaa tgatgcaatt gtattttccg
     3301 gagctttact aggtaatcct ctatgtccat atacagttag catattacct ctccttgcat
     3361 ttttattttt ttaattaacg taactgtatt atcacattaa tcgcactttt atttccatta
     3421 aaaagagatg aatatcataa ataaagaagt cgatagattc gtattgatta tggagttaat
     3481 ctacgtctca tctcattttt aaaaaatcat ttatgtccca agctccattt tgtaatcaag
     3541 tctagttttt ctgtacccct tatctgcaat tttacttagg attgctttta acttacccct
     3601 tatcagcaat tttactgaga actgctttta acgcacctct tatctgcaat tttgcctaga
     3661 actgctttta acgtacctct tatctgcaat tttactgaga actgctttta acttacccct
     3721 tatcagcaat tttgcatgga attgctttta acgtacctct tatctgcaat tttacttaga
     3781 actgctttta acaa
//
LOCUS       DAPSKH010000196         1711 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.144, whole genome shotgun sequence.
ACCESSION   DAPSKH010000196 DAPSKH010000000
VERSION     DAPSKH010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1711
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.144"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            <1..740
                     /locus_tag="RPH49_002807"
     CDS             <1..740
                     /locus_tag="RPH49_002807"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDY5125880.1"
                     /translation="IQYLLKYNNNIWNEWAFENYVQSDDYHGPDMTDFGHRSQQDPEF
                     NEQYKEEMKKFKERILNDDAFAKKYGNLGNVYGKQWRDWEDKNGNHYDQLKSVIQQIK
                     TNPNSRRHIVSAWNPTEIDSMALPPCHTMFQFYVQEGKLNCQLYQRSADIFLGVPFNI
                     ASYALLTHLVAKECGLEVGEFIHTFGDAHIYSNHMDAIHTQLSRDSYLPPQLKINTDK
                     SIFDINYEDLELINYESHPAIKAPIAV"
     gene            782..1267
                     /gene="dfrC"
                     /locus_tag="RPH49_002808"
     CDS             782..1267
                     /gene="dfrC"
                     /locus_tag="RPH49_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001830952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrC"
                     /protein_id="HDY5125881.1"
                     /translation="MTLSIIVAHDKQRVIGYQNQLPWHLPNDLKHIKQLTTGNTLVMA
                     RKTFNSIGKPLPNRRNVVLTNQASFHHEGVDVINSLDEIKELSGHVFIFGGQTLYEAM
                     IDQVDDMYITVIDGKFQGDTFFPPYTFENWEVESSVEGQLDEKNTIPHTFLHLVRRKG
                     K"
     gene            1277..1675
                     /locus_tag="RPH49_002809"
                     /pseudo
     CDS             1277..1675
                     /locus_tag="RPH49_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_499958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
BASE COUNT          633 a          274 c          291 g          513 t
ORIGIN      
        1 acattcaata cctacttaaa tataataaca atatatggaa tgaatgggca tttgaaaatt
       61 atgttcagtc tgatgattat catggaccag acatgacaga ttttggacat cgttcccagc
      121 aagaccctga atttaacgag cagtataaag aagaaatgaa aaaatttaaa gaacgtattc
      181 taaacgatga tgcatttgct aaaaaatatg gcaacttagg gaatgtttat ggtaaacaat
      241 ggagagattg ggaagataaa aatggaaatc attacgatca attaaaatca gttatacaac
      301 aaattaaaac caatccaaac tctcgacgtc acattgtttc agcatggaat cctactgaaa
      361 tcgattcaat ggcattacca ccttgccaca caatgtttca attttacgta caagagggta
      421 aattaaattg tcaattatat caaagaagtg ctgatatatt tttaggtgtt cctttcaata
      481 ttgcaagtta tgctttactg acacatcttg ttgcaaaaga atgtggactt gaggtgggtg
      541 aattcattca tacatttgga gatgcacata tttattccaa tcatatggat gcaatacata
      601 cacaattatc aagagatagt tatctaccac ctcaattaaa aattaataca gataaatcaa
      661 tttttgatat taattatgaa gatttagaat tgataaatta tgaatcacac cctgctatta
      721 aagcacctat tgcggtataa aaagatgcat taatatttcg catacagaaa ggaggtatac
      781 catgacatta tcaataattg tcgctcacga taaacaaaga gtcattgggt accaaaatca
      841 attaccttgg cacttaccaa atgatttaaa gcatattaaa caactgacca ctgggaatac
      901 acttgtaatg gcacggaaaa cttttaattc tatagggaag ccattgccaa atagacgtaa
      961 cgtcgtactc actaaccaag cttcatttca ccatgaaggg gtagatgtta taaactctct
     1021 tgatgaaatt aaagagttat ctggtcatgt ttttatattt ggaggacaaa cgttatacga
     1081 agcaatgatt gaccaggtag atgatatgta tatcacagta atagatggaa agtttcaagg
     1141 agacacattc tttccaccat acacattcga aaactgggaa gtcgaatctt cagtagaagg
     1201 tcaactagat gaaaaaaata ctataccgca tacattctta catttagtgc gtagaaaagg
     1261 gaaataggag gcaattatgg ctaaacaaat tatcgtcacg gattcaacct ctgatttatc
     1321 acatgaatat ttaaaacaac ataacattca tgttatacca ttaagcctga caatcgacgg
     1381 gaaatcttac actgatcaag ttgatatctc ttcaagtgag tatatcgatc atattgaaaa
     1441 tgatgcagac gtcaaaacaa gtcaaccacc tattggtcga tttattgaaa catatgagca
     1501 attagctcaa gatgacgttg aaattataag tattcatctt tcgtcaggct taagtggtac
     1561 ttataatact gctgttcaag cgagccatat ggtagatggt aatattacag tgattgattc
     1621 taaatctatt tcgtttgggt taggttatca aattaagcaa attgttgaat tggttctgtt
     1681 gcaaagtaaa aaaatatagc taaccactaa t
//
LOCUS       DAPSKH010000197         1595 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.147, whole genome shotgun sequence.
ACCESSION   DAPSKH010000197 DAPSKH010000000
VERSION     DAPSKH010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1595
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.147"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            37..1476
                     /locus_tag="RPH49_002810"
                     /note="aph(2'')-Ia"
     CDS             37..1476
                     /locus_tag="RPH49_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDY5125882.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYGGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          681 a          116 c          273 g          525 t
ORIGIN      
        1 gtatatgtat atgattatga aaaaggtgat aaataaatga atatagttga aaatgaaata
       61 tgtataagaa ctttaataga tgatgatttt cctttgatgt taaaatggtt aactgatgaa
      121 agagtattag aattttatgg tggtagagat aaaaaatata cattagaatc attaaaaaaa
      181 cattatacag agccttggga agatgaagtt tttagagtaa ttattgaata taacaatgtt
      241 cctattggat atggacaaat atataaaatg tatgatgagt tatatactga ttatcattat
      301 ccaaaaactg atgagatagt ctatggtatg gatcaattta taggagagcc aaattattgg
      361 agtaaaggaa ttggtacaag atatattaaa ttgatttttg aatttttgaa aaaagaaaga
      421 aatgctaatg cagttatttt agaccctcat aaaaataatc caagagcaat aagggcatac
      481 caaaaatctg gttttagaat tattgaagat ttgccagaac atgaattaca cgagggcaaa
      541 aaagaagatt gttatttaat ggaatataga tatgatgata atgccacaaa tgttaaggca
      601 atgaaatatt taattgagca ttactttgat aatttcaaag tagatagtat tgaaataatc
      661 ggtagtggtt atgatagtgt ggcatattta gttaataatg aatacatttt taaaacaaaa
      721 tttagtacta ataagaaaaa aggttatgca aaagaaaaag caatatataa ttttttaaat
      781 acaaatttag aaactaatgt aaaaattcct aatattgaat attcgtatat tagtgatgaa
      841 ttatctatac taggttataa agaaattaaa ggaacttttt taacaccaga aatttattct
      901 actatgtcag aagaagaaca aaatttgtta aaacgagata ttgccagttt tttaagacaa
      961 atgcacggtt tagattatac agatattagt gaatgtacta ttgataataa acaaaatgta
     1021 ttagaagagt atatattgtt gcgtgaaact atttataatg atttaactga tatagaaaaa
     1081 gattatatag aaagttttat ggaaagacta aatgcaacaa cagtttttga gggtaaaaag
     1141 tgtttatgcc ataatgattt tagttgtaat catctattgt tagatggcaa taatagatta
     1201 actggaataa ttgattttgg agattctgga attatagatg aatattgtga ttttatatac
     1261 ttacttgaag atagtgaaga agaaatagga acaaattttg gagaagatat attaagaatg
     1321 tatggaaata tagatattga gaaagcaaaa gaatatcaag atatagttga agaatattat
     1381 cctattgaaa ctattgttta tggaattaaa aatattaaac aggaatttat cgaaaatggt
     1441 agaaaagaaa tttataaaag gacttataaa gattgattat ataatatatg aaaagctatt
     1501 ataaaagaca ttagtattaa atagtttaaa aaaatgaaaa ataataaagg aagtgagtca
     1561 agtccagact cctgtgtaaa atgctataca atgtt
//
LOCUS       DAPSKH010000198         1526 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.150, whole genome shotgun sequence.
ACCESSION   DAPSKH010000198 DAPSKH010000000
VERSION     DAPSKH010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1526
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.150"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            64..1050
                     /locus_tag="RPH49_002811"
     CDS             64..1050
                     /locus_tag="RPH49_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer MecR1"
                     /protein_id="HDY5125883.1"
                     /translation="MLSSFLMLSIISSLLTICVIFLVRMLYIKYTQNIMSHKIWLLVL
                     VSTLIPLIPFYKISNFTFSKDMMNRNVSDTTSSVSHMLDGQQSSVTKDLAINVNQFET
                     SNITYMILLIWVFGSLLCLFYMIKAFRQIDVIKSSSLESSYLNERLKVCQSKMQFYKK
                     HITISYSSNIDNPMVFGLVKSQIVLPTVVVETMNDKEIEYIILHELSHVKSHDLIFNQ
                     LYVVFKMIFWFNPALYISKTMMDNDCEKVCDRNVLKILNRHEHIRYGESILKCSILKS
                     QHINNVAAQYLLGFNSNIKERVKYIALYDSMPKPNRNKRIVAYIVCSISSFT"
     gene            1022..1282
                     /locus_tag="RPH49_002812"
     CDS             1022..1282
                     /locus_tag="RPH49_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3387 domain-containing protein"
                     /protein_id="HDY5125884.1"
                     /translation="MYVVYRASHETAKEALGDKELRAIAHELTKTVKDNMSVDWSKRD
                     SAKAKMRVQVRRLLKKYGYPPDLQKMAVEQVVEQAELMASQQ"
     gene            complement(1273..>1526)
                     /locus_tag="RPH49_002813"
     CDS             complement(1273..>1526)
                     /locus_tag="RPH49_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011274780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HDY5125885.1"
                     /translation="VFGFMKAILGFTRMSVRGLNKVKRELGFVLMALNIRKVVAQRAE
                     NNQKIYKKDNFYIISIEIVFFHLSKNFMSRTHYDLFFYC"
BASE COUNT          549 a          210 c          253 g          514 t
ORIGIN      
        1 attacaaatg tagtatttat gtcaaaataa tgttataatt tttgtgatat ggaggtgtag
       61 aaggtgttat catctttttt aatgttaagt ataatcagtt cattgctcac gatatgtgta
      121 atttttttag tgagaatgct ctatataaaa tatactcaaa atattatgtc acataagatt
      181 tggttattag tgctcgtctc cacgttaatt ccattaatac cattttacaa aatatcgaat
      241 tttacatttt caaaagatat gatgaatcga aatgtatctg acacgacttc ttcggttagt
      301 catatgttag atggtcaaca atcatctgtt acgaaagact tagcaattaa tgttaatcag
      361 tttgagacct caaatataac gtatatgatt cttttgatat gggtatttgg tagtttgttg
      421 tgcttatttt atatgattaa ggcattccga caaattgatg ttattaaaag ttcgtcattg
      481 gaatcgtcat atcttaatga acgacttaaa gtatgtcaaa gtaagatgca gttctacaaa
      541 aagcatataa caattagtta tagttcaaac attgataatc cgatggtatt tggtttagtg
      601 aaatcccaaa ttgtactacc aactgtcgta gtcgaaacca tgaatgacaa agaaattgaa
      661 tatattattc tacatgaact atcacatgtg aaaagtcatg acttaatatt caaccagctt
      721 tatgttgttt ttaaaatgat attctggttt aatcctgcac tatatataag taaaacaatg
      781 atggacaatg actgtgaaaa agtatgtgat agaaacgttt taaaaatttt gaatcgccat
      841 gaacatatac gttatggtga atcgatatta aaatgctcta ttttaaaatc tcagcacata
      901 aataatgtgg cagcacaata tttactaggt tttaattcaa atattaaaga acgtgttaag
      961 tatattgcac tttatgattc aatgcctaaa cctaatcgaa acaagcgtat tgttgcgtat
     1021 attgtatgta gtatatcgag cttcacatga aacagctaaa gaagctttgg gcgataaaga
     1081 gttaagagcc attgcacatg agttaactaa aacagttaag gataacatga gtgttgattg
     1141 gtctaaacga gacagtgcta aagctaaaat gagagttcaa gttagacgcc tattaaagaa
     1201 atatggctat ccaccagatc ttcaaaaaat ggctgtggaa caagttgtag agcaagcaga
     1261 attaatggca agtcagcaat aaaaaaataa atcataatga gtccgggaca taaagttctt
     1321 ggataagtga aaaaagacaa tttctattga aataatatag aaattgtctt ttttataaat
     1381 tttttgatta ttttcagctc gttgagctac tacttttctt atattaagtg ccattaatac
     1441 aaaaccaagt tctcttttga ctttattgag tcctcggaca gacatccgag tgaaacccaa
     1501 aatagccttc ataaatccaa aaacag
//
LOCUS       DAPSKH010000199         1086 bp    DNA     linear   BCT 26-SEP-2023
DEFINITION  TPA_asm: Staphylococcus aureus isolate M6261
            SAMN36316884-rid18951123.guided.161, whole genome shotgun sequence.
ACCESSION   DAPSKH010000199 DAPSKH010000000
VERSION     DAPSKH010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN36316884
            Sequence Read Archive: SRR25159262
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Staphylococcus aureus
  ORGANISM  Staphylococcus aureus
            Bacteria; Bacillati; Bacillota; Bacilli; Bacillales;
            Staphylococcaceae; Staphylococcus.
REFERENCE   1  (bases 1 to 1086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (01-AUG-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 01-AUG-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001836378.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001836378.1
            Genome Coverage       :: 38x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 08/01/2023 19:32:20
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,815
            CDSs (total)                      :: 2,752
            Genes (coding)                    :: 2,685
            CDSs (with protein)               :: 2,685
            Genes (RNA)                       :: 63
            rRNAs                             :: 3, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 67
            CDSs (without protein)            :: 67
            Pseudo Genes (ambiguous residues) :: 0 of 67
            Pseudo Genes (frameshifted)       :: 31 of 67
            Pseudo Genes (incomplete)         :: 26 of 67
            Pseudo Genes (internal stop)      :: 25 of 67
            Pseudo Genes (multiple problems)  :: 14 of 67
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1086
                     /organism="Staphylococcus aureus"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN36316884-rid18951123.guided.161"
                     /isolate="M6261"
                     /isolation_source="screening"
                     /host="Homo sapiens"
                     /db_xref="taxon:1280"
                     /geo_loc_name="Denmark: Copenhagen"
                     /lat_lon="55.67 N 12.57 E"
                     /collection_date="2017-10-11"
                     /collected_by="general practice"
     gene            complement(<1..342)
                     /locus_tag="RPH49_002814"
     CDS             complement(<1..342)
                     /locus_tag="RPH49_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam sensor/signal transducer BlaR1"
                     /protein_id="HDY5125886.1"
                     /translation="MAKLLIMSIVSFCFIFLLLLFFRYILKRYFNYMLNYKVWYLTLL
                     AGLIPFIPIKFSFFKFNNLNNQEPTVESNSHNLNPNINTTKPVHEFTTDIHKINWDSI
                     DNICTVIWIVLV"
     gene            449..>1086
                     /gene="bla"
                     /locus_tag="RPH49_002815"
     CDS             449..>1086
                     /gene="bla"
                     /locus_tag="RPH49_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase"
                     /protein_id="HDY5125887.1"
                     /translation="MKKLILLIAIALVLSACNSTSSHAKELNNLEKKYNANIGVYALD
                     TKSGKEVKFNADKRFAYASTSKAINSAILLEQVPYNKLNKKVHINKDDIVAYSPILEK
                     YVGKDITLKELIEASMKYSDNTANNKIINEIGGIKKIKKRLKKLGDKVTNPVRYEIEL
                     NYYSPKSKKDTSTPAAFGKTLNKLIANGKLSKKNKNFLLDLMLNNKNGDTLI"
BASE COUNT          462 a          125 c          150 g          349 t
ORIGIN      
        1 aactaaaact atccaaataa ctgtgcagat attatctatt gaatcccaat taatcttatg
       61 gatgtctgtt gtaaactcat gaacaggttt agtggtattt atgttaggat tcaaattgtg
      121 tgaattactt tcaactgtgg gctcttgatt attcaaatta ttaaatttaa aaaaagagaa
      181 tttaataggg atgaaaggaa ttaatcctgc aagaagagtt agataccaaa ctttataatt
      241 taacatataa ttaaaatagc gttttaatat gtacctaaaa aataataaca atagaaatat
      301 aaaacaaaag cttactatgc tcattattaa taacttagcc atttcaacac cttctttcaa
      361 ataattataa taaactattg acgcgaatat tacaattgta atattattga tttatagaaa
      421 ttacaactgt aatattggag ggtatatttt gaaaaagtta atacttttaa ttgcaattgc
      481 tttagtttta agtgcatgta attcaaccag ttcacatgct aaagagttaa ataatttaga
      541 aaagaaatat aatgctaata ttggtgtcta tgcattagat actaaaagtg gtaaggaagt
      601 aaaatttaat gccgataaga gatttgccta tgcttcaact tcaaaagcga taaatagtgc
      661 tattttgtta gaacaagtac cttataataa gttaaataaa aaagtacata ttaacaaaga
      721 tgatatagtt gcttattctc ctattttaga aaaatatgta ggaaaagata tcactttaaa
      781 agaacttatt gaggcttcaa tgaagtatag tgataataca gcaaacaata aaattataaa
      841 cgaaatcggt ggaatcaaaa aaattaaaaa acgtttaaaa aaattgggag ataaagtaac
      901 aaatccagtt agatatgaaa tagaattaaa ttactattca ccaaagagca aaaaagatac
      961 ttcaacgcct gctgctttcg gcaagacttt aaataaactt atcgcaaatg gaaaattaag
     1021 caaaaaaaat aaaaatttct tacttgattt aatgttaaat aataaaaacg gagacacttt
     1081 aattaa
//
